locus-tag	class	description
CCZ37_00005	ENOG4105EAB	amino acid AbC transporter
CCZ37_00010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CCZ37_00015	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CCZ37_00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CCZ37_00025	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CCZ37_00035	ENOG4105JKW	Valine--pyruvate aminotransferase
CCZ37_00040	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
CCZ37_00045	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
CCZ37_00060	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
CCZ37_00075	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
CCZ37_00080	ENOG4105C7B	Threonine dehydratase
CCZ37_00085	ENOG4105C01	Dihydroxy-acid dehydratase
CCZ37_00090	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CCZ37_00095	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
CCZ37_00105	ENOG4105C0P	Mg chelatase subunit ChlI
CCZ37_00115	ENOG4108Z33	Thiol disulfide Interchange Protein
CCZ37_00120	ENOG4105E27	serine threonine protein kinase
CCZ37_00135	ENOG4105PC1	Conserved Protein
CCZ37_00145	ENOG4108UT2	hemolysin iii
CCZ37_00150	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
CCZ37_00155	ENOG4105C1A	potassium transporter peripheral membrane
CCZ37_00160	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CCZ37_00165	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CCZ37_00175	ENOG4108WZM	domain protein
CCZ37_00180	ENOG4105C79	DNA protecting protein DprA
CCZ37_00185	ENOG4108RPN	Protein smg homolog
CCZ37_00190	ENOG4108WI1	Dna topoisomerase
CCZ37_00195	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
CCZ37_00200	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
CCZ37_00205	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CCZ37_00210	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
CCZ37_00215	ENOG4105E2X	shikimate dehydrogenase
CCZ37_00220	ENOG4105SG3	Protein of unknown function (DUF1488)
CCZ37_00225	ENOG4108Z0R	Transferase
CCZ37_00300	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
CCZ37_00305	ENOG4105BZU	Histidine kinase
CCZ37_00310	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CCZ37_00315	ENOG4105CUX	Signal transduction histidine kinase
CCZ37_00325	ENOG4105C5F	glutamine synthetase
CCZ37_00335	ENOG4107S2Z	UPF0761 membrane protein
CCZ37_00340	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
CCZ37_00345	ENOG4105SUU	thioesterase domain
CCZ37_00355	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
CCZ37_00360	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
CCZ37_00365	ENOG4105VEJ	Heat shock protein
CCZ37_00370	ENOG4108XKW	General secretion pathway protein C
CCZ37_00380	ENOG4107QHF	type ii secretion system protein e
CCZ37_00385	ENOG4105D7Q	type ii secretion system
CCZ37_00390	ENOG4108VAU	general secretion pathway protein G
CCZ37_00395	ENOG4105VWV	general secretion pathway protein h
CCZ37_00400	ENOG4105X5Z	General secretion pathway protein I
CCZ37_00405	ENOG4108WWZ	General secretion pathway protein J
CCZ37_00410	ENOG4108RTD	type II secretion system protein K
CCZ37_00415	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
CCZ37_00420	ENOG4105U1E	general secretion pathway protein M
CCZ37_00425	ENOG4105PIC	general secretion pathway protein N
CCZ37_00430	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
CCZ37_00435	ENOG4107RK2	ADP-ribose diphosphatase NudE
CCZ37_00440	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
CCZ37_00445	ENOG4105MJ2	Competence protein
CCZ37_00460	ENOG4105BZM	domain protein
CCZ37_00465	ENOG4108RRZ	Transcription elongation factor GreB
CCZ37_00470	ENOG4105RA2	Membrane
CCZ37_00480	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CCZ37_00485	ENOG4105E0F	Histidine kinase
CCZ37_00490	ENOG4105C2W	permease
CCZ37_00495	ENOG4105CB5	ATP-dependent DNA helicase recG
CCZ37_00500	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CCZ37_00505	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
CCZ37_00510	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CCZ37_00515	ENOG4105EX9	Membrane
CCZ37_00520	ENOG4105C9X	ppx gppa phosphatase
CCZ37_00525	ENOG4105C1J	atp-dependent rna helicase
CCZ37_00530	ENOG4105K63	Thioredoxin
CCZ37_00535	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
CCZ37_00545	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
CCZ37_00555	ENOG4107QK7	reductase
CCZ37_00600	ENOG410601J	HemY protein
CCZ37_00605	ENOG4105ECF	c-methyltransferase
CCZ37_00610	ENOG41076E6	Uroporphyrinogen-III Synthase
CCZ37_00615	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
CCZ37_00620	ENOG4107T0K	Adenylate cyclase
CCZ37_00625	ENOG4105XQ6	frataxin-like protein
CCZ37_00635	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CCZ37_00640	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CCZ37_00650	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CCZ37_00655	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
CCZ37_00660	ENOG4106IUH	DTW domain containing protein
CCZ37_00670	ENOG4105DQF	Hydrolase
CCZ37_00675	ENOG4108EUD	Lysophospholipase
CCZ37_00680	ENOG410829K	Lysine exporter protein (Lyse ygga)
CCZ37_00685	ENOG4105D58	Diguanylate phosphodiesterase
CCZ37_00690	ENOG4108RMU	ferritin dps family protein
CCZ37_00725	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
CCZ37_00735	ENOG4106H78	methyltransferase
CCZ37_00740	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CCZ37_00745	ENOG4105CAK	Cell division ATP-binding protein ftsE
CCZ37_00750	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
CCZ37_00755	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CCZ37_00760	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
CCZ37_00765	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
CCZ37_00770	ENOG4105X6C	Flagellar basal body-associated protein FliL
CCZ37_00775	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
CCZ37_00780	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
CCZ37_00785	ENOG4105E55	glycerol-3-phosphate acyltransferase
CCZ37_00790	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CCZ37_00800	ENOG4107R73	Mate efflux family protein
CCZ37_00805	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
CCZ37_00815	ENOG4108Y73	Membrane
CCZ37_00845	ENOG4105C94	Transporter
CCZ37_00855	ENOG4108UTZ	Dihydroxyacetone kinase
CCZ37_00860	ENOG4105CMT	Dihydroxyacetone kinase
CCZ37_00875	ENOG4108ITV	Inner membrane protein yqcE
CCZ37_00910	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
CCZ37_00915	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CCZ37_00920	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CCZ37_00925	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
CCZ37_00965	ENOG4105JIM	Phosphatidylserine synthase
CCZ37_00975	ENOG4105D4A	Cell wall formation (By similarity)
CCZ37_00980	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
CCZ37_00985	ENOG4105CS9	pantothenic acid kinase
CCZ37_01010	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CCZ37_01015	ENOG4105PM1	preprotein translocase subunit SecE
CCZ37_01020	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
CCZ37_01025	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CCZ37_01030	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CCZ37_01035	ENOG4108VZM	50s ribosomal protein L10
CCZ37_01040	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CCZ37_01045	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CCZ37_01050	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CCZ37_01055	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
CCZ37_01060	ENOG4105E09	nadh pyrophosphatase
CCZ37_01065	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
CCZ37_01070	ENOG41062JF	Transcriptional regulator
CCZ37_01080	ENOG41063SB	peptidase
CCZ37_01085	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CCZ37_01095	ENOG4107QWE	)-transporter
CCZ37_01100	ENOG4105DJ4	phosphatidylserine decarboxylase
CCZ37_01105	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CCZ37_01110	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
CCZ37_01155	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
CCZ37_01160	ENOG4105K8N	protein family UPF0079, ATPase
CCZ37_01165	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CCZ37_01170	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
CCZ37_01175	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CCZ37_01180	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
CCZ37_01185	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CCZ37_01190	ENOG4107QJR	hflk protein
CCZ37_01195	ENOG4105EPW	hflc protein
CCZ37_01205	ENOG41069P5	Protein slyX homolog
CCZ37_01215	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CCZ37_01220	ENOG4105WWK	YheO domain protein
CCZ37_01225	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
CCZ37_01230	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
CCZ37_01240	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CCZ37_01245	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CCZ37_01255	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CCZ37_01260	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
CCZ37_01265	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
CCZ37_01270	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CCZ37_01275	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CCZ37_01285	ENOG4105CDU	Replicative dna helicase
CCZ37_01290	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CCZ37_01295	ENOG4107QP8	phosphohexose isomerase
CCZ37_01305	ENOG4105MYN	Zinc uptake regulation protein
CCZ37_01310	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CCZ37_01330	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
CCZ37_01335	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
CCZ37_01340	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
CCZ37_01420	ENOG4105EEQ	Na H antiporter
CCZ37_01425	ENOG4105C3R	Methionine synthase
CCZ37_01430	ENOG4105CFH	Aspartokinase
CCZ37_01435	ENOG4105C5R	Aminotransferase
CCZ37_01450	ENOG4105CJW	magnesium transporter
CCZ37_01465	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
CCZ37_01470	ENOG41086KC	Transcriptional regulator
CCZ37_01475	ENOG4108UUM	single-stranded DNA-binding protein
CCZ37_01480	ENOG41062P1	Diguanylate cyclase phosphodiesterase
CCZ37_01515	ENOG4107QHF	type ii secretion system protein e
CCZ37_01520	ENOG4105D7Q	type ii secretion system
CCZ37_01535	ENOG4105X0D	Fimbrial protein
CCZ37_01565	ENOG4105DFF	Rod shape-determining protein mreb
CCZ37_01570	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
CCZ37_01575	ENOG4105VQ7	Rod shape-determining protein MreD
CCZ37_01580	ENOG4108Z03	MAF-like protein
CCZ37_01585	ENOG4105C03	ribonuclease
CCZ37_01590	ENOG4105QD6	exported protein
CCZ37_01600	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
CCZ37_01605	ENOG4105CEU	Arginine dihydrolase
CCZ37_01625	ENOG41081QV	Universal stress protein
CCZ37_01645	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
CCZ37_01650	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CCZ37_01655	ENOG4105D5Q	Arginine ornithine antiporter
CCZ37_01660	ENOG4105EAH	synthase
CCZ37_01670	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CCZ37_01675	ENOG4105K46	50S ribosomal protein l27
CCZ37_01680	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CCZ37_01685	ENOG4105DWK	Membrane
CCZ37_01690	ENOG4107XM3	UPF0442 protein
CCZ37_01700	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
CCZ37_01705	ENOG4105NWN	ApaG protein
CCZ37_01710	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CCZ37_01715	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
CCZ37_01720	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
CCZ37_01725	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
CCZ37_01730	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
CCZ37_01780	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
CCZ37_01785	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
CCZ37_01790	ENOG4105CEN	a g-specific adenine glycosylase
CCZ37_01795	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CCZ37_01800	ENOG4105CSV	Glutaminase
CCZ37_01805	ENOG4105CSA	Coproporphyrinogen iii oxidase
CCZ37_01810	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CCZ37_01820	ENOG4105VZ9	UPF0235 protein
CCZ37_01825	ENOG4108VIA	integral membrane protein
CCZ37_01830	ENOG4105II7	pyrroline-5-carboxylate reductase
CCZ37_01835	ENOG4105DFA	alanine racemase domain protein
CCZ37_01840	ENOG4105CZX	twitching motility protein
CCZ37_01845	ENOG4105CZX	twitching motility protein
CCZ37_01850	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CCZ37_01855	ENOG4108UJU	UPF0301 protein
CCZ37_01860	ENOG4105D7Z	glutathione synthase
CCZ37_01865	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
CCZ37_01870	ENOG4105RWS	endonuclease I
CCZ37_01880	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CCZ37_01930	ENOG4105MZU	cell filamentation protein
CCZ37_01940	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CCZ37_01945	ENOG4105BZA	Phosphoglycerate kinase
CCZ37_01955	ENOG4105D2N	Aldolase
CCZ37_01960	ENOG4105D64	Mechanosensitive ion channel
CCZ37_01965	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
CCZ37_01970	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
CCZ37_01980	ENOG4105BZU	Histidine kinase
CCZ37_01990	ENOG4105CA9	Pyruvate kinase
CCZ37_01995	ENOG410804X	Transcriptional regulator
CCZ37_02000	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CCZ37_02025	ENOG4108YZN	class I peptide chain release factor
CCZ37_02030	ENOG4108WC9	type VI secretion system effector, hcp1 family
CCZ37_02035	ENOG4105CS6	Rhs element vgr protein
CCZ37_02105	ENOG4105CAF	HipA N-terminal domain protein
CCZ37_02120	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CCZ37_02125	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CCZ37_02130	ENOG4105KTH	gatB Yqey
CCZ37_02135	ENOG4105VCC	30S ribosomal protein S21
CCZ37_02140	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CCZ37_02150	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
CCZ37_02155	ENOG4107ZVW	dihydroneopterin aldolase
CCZ37_02160	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CCZ37_02165	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CCZ37_02170	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
CCZ37_02175	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
CCZ37_02180	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CCZ37_02185	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
CCZ37_02190	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
CCZ37_02195	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CCZ37_02200	ENOG4108K5P	(LipO)protein
CCZ37_02205	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CCZ37_02210	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CCZ37_02215	ENOG4105C6T	cysteine synthase
CCZ37_02220	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
CCZ37_02225	ENOG4108I5D	sulfate abc transporter
CCZ37_02230	ENOG4105ECW	sulfate abc transporter
CCZ37_02235	ENOG4108IJ6	ABC transporter
CCZ37_02240	ENOG4107TH8	cina domain protein
CCZ37_02245	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CCZ37_02250	ENOG4105Y3E	Modulates RecA activity (By similarity)
CCZ37_02255	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CCZ37_02260	ENOG4105CFH	Aspartokinase
CCZ37_02265	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
CCZ37_02315	ENOG4107QSA	Oxaloacetate decarboxylase
CCZ37_02320	ENOG4105D9Q	decarboxylase (Beta subunit)
CCZ37_02325	ENOG4105CPQ	Dehydrogenase
CCZ37_02330	ENOG4105W39	Membrane
CCZ37_02340	ENOG4105D9M	gamma-glutamylcysteine synthetase
CCZ37_02345	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
CCZ37_02350	ENOG4108JU6	CBS domain protein
CCZ37_02355	ENOG4106KVJ	cytochrome C assembly protein
CCZ37_02360	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CCZ37_02365	ENOG4105K5M	30s ribosomal protein S16
CCZ37_02370	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CCZ37_02375	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CCZ37_02380	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CCZ37_02385	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
CCZ37_02390	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
CCZ37_02395	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CCZ37_02400	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
CCZ37_02405	ENOG4105D7Q	type ii secretion system
CCZ37_02410	ENOG4107QHF	type ii secretion system protein e
CCZ37_02415	ENOG4105X0D	Fimbrial protein
CCZ37_02420	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
CCZ37_02430	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
CCZ37_02435	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CCZ37_02440	ENOG4105T95	Thiol disulfide interChange protein
CCZ37_02445	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CCZ37_02450	ENOG41073TP	transcriptional regulator
CCZ37_02455	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
CCZ37_02460	ENOG4107QSN	dihydrolipoamide acetyltransferase
CCZ37_02465	ENOG4107QN2	dihydrolipoyl dehydrogenase
CCZ37_02470	ENOG410630P	Transcriptional regulator
CCZ37_02475	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
CCZ37_02480	ENOG41077A9	carbonic anhydrase
CCZ37_02485	ENOG4105CHH	sulfate transporter
CCZ37_02490	ENOG4105DA5	(ABC) transporter
CCZ37_02495	ENOG4105E3A	(ABC) transporter
CCZ37_02505	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
CCZ37_02510	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CCZ37_02515	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CCZ37_02520	ENOG4105DJ0	Poly(A) Polymerase
CCZ37_02525	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
CCZ37_02530	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CCZ37_02535	ENOG4105PW4	Sugar fermentation stimulation protein homolog
CCZ37_02540	ENOG4105CQ7	ATP-dependent helicase
CCZ37_02545	ENOG4105BZ4	penicillin-binding protein
CCZ37_02550	ENOG4105D78	K07001 NTE family protein
CCZ37_02555	ENOG4107QIJ	Aconitate hydratase 2
CCZ37_02590	ENOG4105DIK	(ABC) transporter
CCZ37_02605	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CCZ37_02610	ENOG410804D	Sensor Signal Transduction Histidine Kinase
CCZ37_02615	ENOG4105D05	Receptor
CCZ37_02620	ENOG4105BZW	Glycerate kinase
CCZ37_02625	ENOG4105XTV	UPF0231 protein
CCZ37_02630	ENOG4108YZA	Nitrogen regulatory protein pii
CCZ37_02650	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CCZ37_02655	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
CCZ37_02665	ENOG4105E2D	ec 3.2.1.52
CCZ37_02670	ENOG4105RD7	BadF BadG BcrA BcrD
CCZ37_02680	ENOG4108JQ7	(ABC) transporter
CCZ37_02685	ENOG4105C3U	ABC transporter
CCZ37_02690	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CCZ37_02705	ENOG4105BZU	Histidine kinase
CCZ37_02710	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
CCZ37_02715	ENOG4105IPI	Membrane
CCZ37_02720	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
CCZ37_02725	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
CCZ37_02740	ENOG4105DR5	peptidase
CCZ37_02745	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CCZ37_02755	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
CCZ37_02760	ENOG4107QE9	Inherit from COG: Membrane
CCZ37_02765	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CCZ37_02770	ENOG4105HBR	Rna-binding protein
CCZ37_02775	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
CCZ37_02780	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CCZ37_02785	ENOG4105EEI	dihydropteroate synthase
CCZ37_02810	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
CCZ37_02815	ENOG4105CHV	Transcription elongation factor NusA
CCZ37_02820	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CCZ37_02825	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CCZ37_02830	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CCZ37_02835	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CCZ37_02840	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CCZ37_02850	ENOG41062A4	Transcriptional regulator
CCZ37_02860	ENOG4106RZ4	Peptidase U32
CCZ37_02865	ENOG4105CFP	Peptidase U32
CCZ37_02870	ENOG4105BZU	Histidine kinase
CCZ37_02875	ENOG4105XPQ	lipid carrier protein
CCZ37_02880	ENOG4108YYD	acetyltransferase
CCZ37_02890	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
CCZ37_02895	ENOG4105BZU	Histidine kinase
CCZ37_02900	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
CCZ37_02905	ENOG4105C1J	atp-dependent rna helicase
CCZ37_02915	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
CCZ37_02925	ENOG4105CRK	lysyL-tRNA synthetase
CCZ37_02930	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CCZ37_02940	ENOG4105CPC	Aldo Keto reductase
CCZ37_02945	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
CCZ37_02950	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CCZ37_02955	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
CCZ37_02960	ENOG4105HF0	Membrane
CCZ37_02965	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CCZ37_02970	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
CCZ37_02980	ENOG41063Z6	transcriptional regulator, lysR family
CCZ37_02985	ENOG41080HT	Transcriptional regulator, arsr family
CCZ37_02990	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
CCZ37_02995	ENOG4105CJR	Integral membrane protein (MviN
CCZ37_03000	ENOG4105DTN	riboflavin biosynthesis protein ribF
CCZ37_03005	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CCZ37_03010	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CCZ37_03015	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
CCZ37_03020	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
CCZ37_03035	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CCZ37_03040	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
CCZ37_03045	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
CCZ37_03050	ENOG4108NEV	two component transcriptional regulator, LytTR family
CCZ37_03055	ENOG4108HRK	Histidine kinase
CCZ37_03060	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CCZ37_03075	ENOG4105C5H	ABC transporter
CCZ37_03080	ENOG4107SC1	transglycosylase
CCZ37_03085	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
CCZ37_03090	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CCZ37_03095	ENOG4108K0B	C-di-gmp phosphodiesterase
CCZ37_03100	ENOG4107XW0	Spermidine putrescine ABC transporter periplasmic spermidine putrescine-binding protein
CCZ37_03110	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
CCZ37_03115	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CCZ37_03120	ENOG4105C34	Pseudouridine synthase
CCZ37_03125	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
CCZ37_03130	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CCZ37_03170	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
CCZ37_03175	ENOG4105CFP	Peptidase U32
CCZ37_03180	ENOG4105DH7	May be involved in recombination (By similarity)
CCZ37_03185	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CCZ37_03190	ENOG4105BZU	Histidine kinase
CCZ37_03200	ENOG4105C9X	ppx gppa phosphatase
CCZ37_03205	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
CCZ37_03210	ENOG4105C8U	phosphate abc transporter
CCZ37_03215	ENOG4105E2Z	phosphate ABC transporter (Permease
CCZ37_03220	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CCZ37_03230	ENOG4106N3A	copper homeostasis protein cutc
CCZ37_03235	ENOG4105D3R	alkyl hydroperoxide reductase
CCZ37_03240	ENOG4105C5Q	Transcriptional regulator
CCZ37_03245	ENOG4107QP3	malate synthase g
CCZ37_03250	ENOG4108I9X	Isocitrate lyase
CCZ37_03255	ENOG4105W87	Cbs domain
CCZ37_03260	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CCZ37_03265	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
CCZ37_03270	ENOG4105VIE	preprotein translocase, subunit YajC
CCZ37_03275	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CCZ37_03280	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CCZ37_03285	ENOG4105ECY	inositol monophosphatase
CCZ37_03290	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
CCZ37_03295	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
CCZ37_03300	ENOG4105C3J	Cysteine desulfurase
CCZ37_03305	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
CCZ37_03310	ENOG4108Z4V	iron-sulfur cluster assembly
CCZ37_03315	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
CCZ37_03320	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
CCZ37_03325	ENOG4108ZIT	Ferredoxin, 2FE-2S
CCZ37_03330	ENOG4105WVQ	Fe-S assembly protein IscX
CCZ37_03335	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CCZ37_03340	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
CCZ37_03355	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
CCZ37_03360	ENOG4105CUT	histidyl-tRNA synthetase
CCZ37_03365	ENOG4105N21	Membrane
CCZ37_03370	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CCZ37_03375	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CCZ37_03385	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CCZ37_03390	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CCZ37_03395	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CCZ37_03400	ENOG4105DWF	phosphomethylpyrimidine kinase
CCZ37_03410	ENOG4106HK8	GPR1 FUN34 yaaH family protein
CCZ37_03415	ENOG4105BZG	amino acid carrier protein
CCZ37_03420	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CCZ37_03440	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
CCZ37_03460	ENOG41069H0	dihydroorotase EC 3.5.2.3
CCZ37_03490	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CCZ37_03515	ENOG4105DZ1	carboxypeptidase
CCZ37_03540	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CCZ37_03545	ENOG4108Z1B	Cyclase dehydrase
CCZ37_03550	ENOG4105VDB	UPF0125 protein
CCZ37_03555	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CCZ37_03560	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
CCZ37_03565	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CCZ37_03575	ENOG4105CFG	Acts as a chaperone (By similarity)
CCZ37_03580	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CCZ37_03610	ENOG4105CFC	Transporter
CCZ37_03620	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
CCZ37_03625	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
CCZ37_03640	ENOG4105W1I	UPF0253 protein
CCZ37_03645	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CCZ37_03650	ENOG4108R96	Methyltransferase, YaeB family
CCZ37_03655	ENOG4105NRA	50s ribosomal protein l31 type b
CCZ37_03665	ENOG4108UPT	UPF0178 protein
CCZ37_03690	ENOG4105WP7	tRNA pseudouridine synthase C
CCZ37_03695	ENOG4105DR9	pseudouridine synthase
CCZ37_03700	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CCZ37_03705	ENOG4105CTB	Polyprenyl synthetase
CCZ37_03710	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CCZ37_03715	ENOG4105E14	MotA TolQ exbB proton channel
CCZ37_03720	ENOG4106VK6	Flagellar motor protein
CCZ37_03730	ENOG4105ETT	transcriptional Regulator, LysR family
CCZ37_03735	ENOG4105M08	Membrane
CCZ37_03740	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
CCZ37_03745	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
CCZ37_03750	ENOG4105EWT	decarboxylase family
CCZ37_03755	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
CCZ37_03765	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
CCZ37_03770	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
CCZ37_03775	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
CCZ37_03780	ENOG4105D01	(LipO)protein
CCZ37_03785	ENOG4108UMI	ABC transporter, permease
CCZ37_03790	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CCZ37_03795	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
CCZ37_03805	ENOG4105D4X	repressor
CCZ37_03810	ENOG4105C5Y	PTS System
CCZ37_03815	ENOG4105CG3	alpha amylase, catalytic region
CCZ37_03845	ENOG410624X	efflux transporter, rnd family, mfp subunit
CCZ37_03850	ENOG4105BZS	acriflavin resistance protein
CCZ37_03855	ENOG4105KJF	protein tyrosine phosphatase
CCZ37_03860	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
CCZ37_03870	ENOG4105D7W	serine acetyltransferase
CCZ37_03890	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CCZ37_03910	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
CCZ37_03925	ENOG4108MA4	Peptidase M66
CCZ37_03950	ENOG4108QV3	biosynthesis protein
CCZ37_03955	ENOG4105DAY	polysaccharide export protein
CCZ37_03970	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CCZ37_03980	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CCZ37_03990	ENOG4108Z43	UPF0250 protein
CCZ37_03995	ENOG4105DZ1	carboxypeptidase
CCZ37_04000	ENOG4105K6T	rare lipoprotein A
CCZ37_04005	ENOG4105CNI	cell division protein FtsW
CCZ37_04010	ENOG4105CJN	penicillin-binding protein
CCZ37_04015	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
CCZ37_04020	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
CCZ37_04025	ENOG4105DJF	DNA polymerase III, delta' subunit
CCZ37_04030	ENOG4108U2H	Rare lipoprotein B
CCZ37_04035	ENOG4105C8T	Leucyl-tRNA synthetase
CCZ37_04040	ENOG4107PAI	alpha helical protein
CCZ37_04045	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
CCZ37_04050	ENOG4108JU5	Magnesium and cobalt efflux protein
CCZ37_04060	ENOG4105C9A	Phoh family
CCZ37_04065	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CCZ37_04070	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
CCZ37_04075	ENOG4105C5Y	PTS System
CCZ37_04080	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
CCZ37_04085	ENOG4105KZ7	phosphocarrier protein hpr
CCZ37_04090	ENOG4105C6T	cysteine synthase
CCZ37_04095	ENOG4105EXN	Sulfate transport protein CysZ
CCZ37_04100	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
CCZ37_04105	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CCZ37_04110	ENOG41081QG	Porin Gram-negative type
CCZ37_04120	ENOG4108Z6Z	Transcriptional regulator
CCZ37_04130	ENOG4107QX8	SPFH domain, Band 7 family protein
CCZ37_04135	ENOG4107QR8	Thioredoxin
CCZ37_04140	ENOG4105ECP	epimerase
CCZ37_04145	ENOG4108RE9	Phosphodiesterase
CCZ37_04160	ENOG4108DQ1	activator toxR
CCZ37_04165	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CCZ37_04170	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CCZ37_04175	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CCZ37_04180	ENOG4105DUX	Transporter
CCZ37_04185	ENOG4105MDZ	Transcriptional activator rfaH
CCZ37_04190	ENOG4105CAQ	asparagine synthetase
CCZ37_04195	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
CCZ37_04200	ENOG4105E2R	ROK family
CCZ37_04205	ENOG4105CE4	GlcNAc 6-P deacetylase
CCZ37_04210	ENOG4105CI1	PTS System
CCZ37_04215	ENOG4105CX6	glutaminyL-tRNA synthetase
CCZ37_04225	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
CCZ37_04230	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
CCZ37_04235	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CCZ37_04240	ENOG4108S3P	Sporulation domain protein
CCZ37_04245	ENOG4105E96	Colicin v production protein
CCZ37_04250	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
CCZ37_04255	ENOG4105D3Y	Na H antiporter
CCZ37_04260	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
CCZ37_04265	ENOG4105EIY	sodium-type flagellar protein motY
CCZ37_04270	ENOG4108UYE	Lactoylglutathione lyase
CCZ37_04275	ENOG4105CSM	endonuclease III
CCZ37_04280	ENOG4105DZB	Electron transport complex
CCZ37_04285	ENOG4108UQQ	Electron transport complex
CCZ37_04300	ENOG4108R3D	Electron transport complex
CCZ37_04315	ENOG4107RBR	Receptor
CCZ37_04320	ENOG4105E93	esterase
CCZ37_04340	ENOG4105WQI	isochorismatase
CCZ37_04345	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
CCZ37_04350	ENOG4105E4F	Isochorismate synthase
CCZ37_04355	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
CCZ37_04360	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CCZ37_04370	ENOG4105D05	Receptor
CCZ37_04425	ENOG4105DIJ	Phosphoethanolamine transferase
CCZ37_04430	ENOG41080IJ	Diacylglycerol kinase
CCZ37_04435	ENOG4105E0M	Sulfatase
CCZ37_04440	ENOG4105EW9	transcriptional regulator AsnC family
CCZ37_04460	ENOG4105BZU	Histidine kinase
CCZ37_04475	ENOG41062D9	Histidine kinase
CCZ37_04495	ENOG4108I5U	Uridine phosphorylase
CCZ37_04500	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
CCZ37_04510	ENOG4108UHU	Aldolase
CCZ37_04525	ENOG4105RW8	MltA-interacting MipA family protein
CCZ37_04535	ENOG4105BZU	Histidine kinase
CCZ37_04540	ENOG4105BZU	Histidine kinase
CCZ37_04545	ENOG4107QSI	ABC, transporter
CCZ37_04550	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CCZ37_04555	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CCZ37_04560	ENOG4105C3U	ABC transporter
CCZ37_04565	ENOG4108JQ7	(ABC) transporter
CCZ37_04570	ENOG4105CHF	Glutathione S-transferase
CCZ37_04575	ENOG4108DNC	Involved in acetate metabolism (By similarity)
CCZ37_04580	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CCZ37_04585	ENOG4105PQ6	UPF0208 membrane protein
CCZ37_04595	ENOG4105C7J	ABC transporter, permease
CCZ37_04600	ENOG4108JJB	ABC transporter
CCZ37_04605	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
CCZ37_04610	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CCZ37_04620	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
CCZ37_04625	ENOG4105D1H	recombination factor protein RarA
CCZ37_04630	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CCZ37_04635	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
CCZ37_04640	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
CCZ37_04645	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CCZ37_04650	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CCZ37_04655	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
CCZ37_04660	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
CCZ37_04670	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
CCZ37_04685	ENOG4105K59	histidine triad (HIT) protein
CCZ37_04710	ENOG4105D0Y	UPF0227 protein
CCZ37_04715	ENOG4105CEP	NADH dehydrogenase
CCZ37_04720	ENOG4106M3D	hemolysin
CCZ37_04730	ENOG4108JA2	transcriptioN-repair coupling factor
CCZ37_04740	ENOG4105D60	lipoprotein releasing system transmembrane protein
CCZ37_04745	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CCZ37_04750	ENOG4105D60	lipoprotein releasing system transmembrane protein
CCZ37_04760	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
CCZ37_04765	ENOG4105BZ1	(ABC) transporter
CCZ37_04770	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
CCZ37_04775	ENOG4105W49	UPF0434 protein
CCZ37_04780	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
CCZ37_04785	ENOG4105ED1	spovr family
CCZ37_04790	ENOG4106AKX	UPF0229 protein
CCZ37_04795	ENOG4105CYN	Serine protein kinase
CCZ37_04800	ENOG4105XWI	UPF0304 protein
CCZ37_04805	ENOG4105F1A	Pyruvate formate-lyase
CCZ37_04810	ENOG4108NVR	Methyl-accepting chemotaxis
CCZ37_04820	ENOG4105C6N	Formate acetyltransferase
CCZ37_04835	ENOG4108JEH	abc transporter atp-binding protein
CCZ37_04840	ENOG4105E89	ABC transporter
CCZ37_04845	ENOG4105DSP	amino acid AbC transporter
CCZ37_04850	ENOG4106YG3	ABC transporter
CCZ37_04855	ENOG4105CGK	Exodeoxyribonuclease III
CCZ37_04905	ENOG4106428	Protein of unknown function (DUF2496)
CCZ37_04910	ENOG4108URS	primosomal replication protein n''
CCZ37_04920	ENOG4105DVT	helicase
CCZ37_04925	ENOG4105SDR	Outer membrane protein OmpT
CCZ37_04935	ENOG4105K5B	UPF0225 protein
CCZ37_04940	ENOG4105D58	Diguanylate phosphodiesterase
CCZ37_04945	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
CCZ37_04950	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CCZ37_04960	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CCZ37_04965	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CCZ37_04970	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CCZ37_04975	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CCZ37_04980	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CCZ37_04990	ENOG4105KJB	cyd operon protein YbgE
CCZ37_04995	ENOG4107YD3	Thioesterase
CCZ37_05000	ENOG4105E02	MotA TolQ exbB proton channel
CCZ37_05005	ENOG4105M8F	Biopolymer transport protein exbD tolR
CCZ37_05015	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
CCZ37_05020	ENOG4105KCK	Peptidoglycan-associated lipoprotein
CCZ37_05025	ENOG4105UFD	tol-pal system protein YbgF
CCZ37_05030	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
CCZ37_05040	ENOG4105BZU	Histidine kinase
CCZ37_05045	ENOG4108RNS	Exports L-alanine (By similarity)
CCZ37_05065	ENOG4105DEF	Extracellular solute-binding protein, family 5
CCZ37_05075	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CCZ37_05080	ENOG4105C3U	ABC transporter
CCZ37_05085	ENOG4108JQ7	(ABC) transporter
CCZ37_05095	ENOG41060NJ	transcriptional regulator
CCZ37_05105	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
CCZ37_05110	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
CCZ37_05120	ENOG4107RV5	Glycosyl hydrolase family 3 N-terminal domain protein
CCZ37_05130	ENOG4105C26	Dehydrogenase
CCZ37_05145	ENOG41067SE	Tetr family transcriptional regulator
CCZ37_05150	ENOG4107QPN	acyl-Coa dehydrogenase
CCZ37_05185	ENOG4105CQB	FAD linked oxidase domain protein
CCZ37_05200	ENOG4105C84	Histidine ammonia-lyase
CCZ37_05205	ENOG4105CGP	Urocanate hydratase
CCZ37_05210	ENOG41088SP	formiminoglutamate hydrolase
CCZ37_05220	ENOG4105CZE	histidine utilization repressor
CCZ37_05235	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CCZ37_05245	ENOG4105CQ2	DNA polymerase
CCZ37_05250	ENOG4105WH1	Two component transcriptional regulator luxr family
CCZ37_05255	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CCZ37_05290	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CCZ37_05295	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CCZ37_05300	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CCZ37_05310	ENOG4105FQ6	thiopurine methyltransferase
CCZ37_05315	ENOG4107SDU	Methyl-accepting chemotaxis
CCZ37_05320	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
CCZ37_05325	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
CCZ37_05330	ENOG41067MG	lrgb family
CCZ37_05340	ENOG4105CJB	Exodeoxyribonuclease I
CCZ37_05345	ENOG4108ETY	sodium dicarboxylate symporter
CCZ37_05355	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
CCZ37_05360	ENOG4108JJA	ABC, transporter
CCZ37_05370	ENOG4108RC6	RTX toxin
CCZ37_05375	ENOG4105EUK	rtx toxin RtxA
CCZ37_05380	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
CCZ37_05385	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
CCZ37_05390	ENOG4108YZT	Adenosylcobinamide kinase
CCZ37_05405	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
CCZ37_05410	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
CCZ37_05430	ENOG4107RSM	transcriptional regulator
CCZ37_05440	ENOG4108VKG	metal-dependent hydrolase
CCZ37_05455	ENOG41090FY	type IV pilus biogenesis stability protein PilW
CCZ37_05460	ENOG4105CVG	Homoserine O-transsuccinylase
CCZ37_05480	ENOG4107V40	secretion protein, HlyD family
CCZ37_05495	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
CCZ37_05500	ENOG4108V9W	transcriptional regulatory protein
CCZ37_05510	ENOG4107R88	Chemotaxis protein (CheV)
CCZ37_05530	ENOG4105BZU	Histidine kinase
CCZ37_05545	ENOG4105GFG	DUF218 domain
CCZ37_05575	ENOG4105TMB	Formate nitrite transporter
CCZ37_05590	ENOG4108J2R	molybdopterin oxidoreductase
CCZ37_05600	ENOG4105BZU	Histidine kinase
CCZ37_05615	ENOG4105CND	Glycosyl transferase, family 2
CCZ37_05620	ENOG4105CPK	Glycosyl transferase (Group 1
CCZ37_05655	ENOG4107TYR	Glycosyl Transferase
CCZ37_05665	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CCZ37_05680	ENOG4107V1M	polysaccharide export protein
CCZ37_05710	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
CCZ37_05730	ENOG4108JQ2	peptide transport system atp-binding protein
CCZ37_05735	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
CCZ37_05740	ENOG4108EU3	peptide transport system, permease
CCZ37_05745	ENOG4108I5W	peptide transport system, permease protein
CCZ37_05750	ENOG4108J59	Extracellular solute-binding protein, family 5
CCZ37_05755	ENOG4105E51	psp operon transcriptional activator
CCZ37_05760	ENOG41087YS	Phage shock protein A
CCZ37_05765	ENOG4105YYT	phage shock protein B
CCZ37_05775	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CCZ37_05780	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
CCZ37_05790	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CCZ37_05795	ENOG4105C28	cystathionine
CCZ37_05805	ENOG4105C8J	)-transporter
CCZ37_05810	ENOG4108W1A	pseudouridine synthase
CCZ37_05820	ENOG4105CXC	rtn protein
CCZ37_05825	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
CCZ37_05830	ENOG4108VGW	abc transporter atp-binding protein
CCZ37_05835	ENOG4105CXZ	ABC transporter, permease
CCZ37_05840	ENOG4105VNH	ABC transporter solute-binding protein
CCZ37_05850	ENOG4105XZD	Fe-S protein
CCZ37_05865	ENOG4105C1J	atp-dependent rna helicase
CCZ37_05875	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
CCZ37_05880	ENOG4105EB3	Histidine kinase
CCZ37_05895	ENOG4105CFI	type iii restriction protein res subunit
CCZ37_05900	ENOG4105I08	Pseudouridine synthase
CCZ37_05905	ENOG4105C2C	drug resistance transporter, Bcr CflA
CCZ37_05915	ENOG4105CGD	Nad-dependent epimerase dehydratase
CCZ37_05920	ENOG4105UQX	Mate efflux family protein
CCZ37_05925	ENOG4108I0Y	(ABC) transporter
CCZ37_05940	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
CCZ37_05960	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
CCZ37_05990	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CCZ37_05995	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CCZ37_06000	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CCZ37_06005	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CCZ37_06010	ENOG4108N3W	hemolysin secretion protein
CCZ37_06020	ENOG4105EIP	mannose-6-phosphate isomerase
CCZ37_06025	ENOG4105DM4	PTS System
CCZ37_06030	ENOG4108CIP	transcriptional regulator
CCZ37_06040	ENOG4108YRF	PTS System
CCZ37_06050	ENOG41080IJ	Diacylglycerol kinase
CCZ37_06055	ENOG4105GR3	Histidine kinase
CCZ37_06060	ENOG4107EXC	regulatoR
CCZ37_06090	ENOG4105CR4	methylisocitrate lyase
CCZ37_06095	ENOG4105BZN	citrate synthase
CCZ37_06100	ENOG4108I0Z	Aconitate hydratase
CCZ37_06105	ENOG4105C7F	AcnD-accessory protein PrpF
CCZ37_06120	ENOG410667J	hydrolase
CCZ37_06125	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
CCZ37_06130	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
CCZ37_06140	ENOG4105CDV	Ompa motb domain protein
CCZ37_06195	ENOG4105DR4	Methyltransferase
CCZ37_06200	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
CCZ37_06205	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
CCZ37_06210	ENOG4108MN8	Membrane
CCZ37_06215	ENOG4105CDA	abc transporter atp-binding protein
CCZ37_06220	ENOG4105DRP	amino acid AbC transporter
CCZ37_06225	ENOG4105EZ7	amino acid ABC transporter
CCZ37_06230	ENOG4107QXX	ABC transporter
CCZ37_06235	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CCZ37_06245	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CCZ37_06250	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
CCZ37_06270	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CCZ37_06275	ENOG4105DY2	Paraquat-inducible protein b
CCZ37_06280	ENOG4105H2K	paraquat-inducible protein a
CCZ37_06285	ENOG4105BZ1	(ABC) transporter
CCZ37_06290	ENOG4108ZGC	gaf domain protein
CCZ37_06295	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
CCZ37_06300	ENOG4105CN1	protease
CCZ37_06310	ENOG4105CD8	aminopeptidase N
CCZ37_06320	ENOG4105C7I	Dehydrogenase
CCZ37_06325	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
CCZ37_06330	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
CCZ37_06335	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
CCZ37_06345	ENOG4105C5H	ABC transporter
CCZ37_06360	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
CCZ37_06365	ENOG4105DAN	ATP-dependent protease
CCZ37_06370	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
CCZ37_06390	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
CCZ37_06405	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
CCZ37_06415	ENOG4105C59	p-type ATPase
CCZ37_06430	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
CCZ37_06435	ENOG4105Q9Y	Universal stress protein
CCZ37_06440	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
CCZ37_06460	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CCZ37_06465	ENOG4105F38	ABC transporter, permease
CCZ37_06470	ENOG4105D38	putrescine abc transporter
CCZ37_06475	ENOG4107RUE	extracellular solute-binding protein family 1
CCZ37_06480	ENOG4107RUE	extracellular solute-binding protein family 1
CCZ37_06485	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
CCZ37_06490	ENOG4105C5H	ABC transporter
CCZ37_06495	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
CCZ37_06500	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
CCZ37_06510	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
CCZ37_06515	ENOG4106IUH	DTW domain containing protein
CCZ37_06525	ENOG4107TT5	NLP P60 protein
CCZ37_06535	ENOG4105FGM	Fructosamine kinase
CCZ37_06545	ENOG4107QI1	Mate efflux family protein
CCZ37_06555	ENOG4108NRW	Phospholipase, patatin family
CCZ37_06570	ENOG4109015	Biopolymer transport protein exbD tolR
CCZ37_06605	ENOG4108RXX	maleylacetoacetate isomerase
CCZ37_06615	ENOG4105F1J	Homogentisate 1,2-dioxygenase
CCZ37_06620	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
CCZ37_06635	ENOG4105BZG	amino acid carrier protein
CCZ37_06640	ENOG410829K	Lysine exporter protein (Lyse ygga)
CCZ37_06645	ENOG4105CTD	carboxy-peptidase
CCZ37_06650	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CCZ37_06665	ENOG4105CQ7	ATP-dependent helicase
CCZ37_06685	ENOG4105BZU	Histidine kinase
CCZ37_06695	ENOG4105CFG	Acts as a chaperone (By similarity)
CCZ37_06705	ENOG4105C0A	alcohol dehydrogenase
CCZ37_06725	ENOG4105DDV	Transcriptional regulator (LacI family
CCZ37_06730	ENOG4105CS2	ec 3.2.1.21
CCZ37_06735	ENOG4105C1J	atp-dependent rna helicase
CCZ37_06740	ENOG4107QY8	reductase
CCZ37_06745	ENOG4105CUW	cytochrome C-TYPE protein
CCZ37_06750	ENOG4105VEQ	Cold shock protein
CCZ37_06760	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CCZ37_06765	ENOG4105BZU	Histidine kinase
CCZ37_06770	ENOG4105C8P	)-transporter
CCZ37_06775	ENOG4108NVR	Methyl-accepting chemotaxis
CCZ37_06780	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CCZ37_06795	ENOG4105D9U	N-acetyltransferase
CCZ37_06800	ENOG4108JU8	Transcriptional regulator
CCZ37_06805	ENOG4106K28	UPF0283 membrane protein
CCZ37_06810	ENOG4105CM6	amino acid regulated cytosolic protein
CCZ37_06825	ENOG4105CRQ	synthase (Component I)
CCZ37_06830	ENOG4105P8F	nudix hydrolase
CCZ37_06835	ENOG4105C44	Serine transporter
CCZ37_06840	ENOG4105EJQ	L-serine dehydratase
CCZ37_06845	ENOG4105Q9Y	Universal stress protein
CCZ37_06850	ENOG4105D65	subunit l
CCZ37_06855	ENOG4105MKQ	Monovalent cation H antiporter subunit C
CCZ37_06860	ENOG4108JPZ	Monovalent cation H antiporter subunit D
CCZ37_06865	ENOG4105SC1	monovalent cation H antiporter subunit E
CCZ37_06870	ENOG41080TA	Multiple resistance and ph regulation protein f
CCZ37_06875	ENOG4105KJM	monovalent cation h antiporter subunit g
CCZ37_06885	ENOG4108K8S	endonuclease I
CCZ37_06890	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
CCZ37_06895	ENOG4108NVR	Methyl-accepting chemotaxis
CCZ37_06900	ENOG4105C5S	asparaginyl-tRNA synthetase
CCZ37_06910	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CCZ37_06915	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
CCZ37_06920	ENOG4105BZU	Histidine kinase
CCZ37_06925	ENOG4108V3W	Chemotaxis protein, CheW
CCZ37_06935	ENOG4105CBS	Chea signal transduction histidine kinase
CCZ37_06945	ENOG4108VYJ	response regulator receiver protein
CCZ37_06950	ENOG4105C8Q	Methyl-accepting chemotaxis
CCZ37_06955	ENOG4105CGF	Aromatic amino acid aminotransferase
CCZ37_06960	ENOG41080XQ	Signal transduction protein with cbs domains
CCZ37_06970	ENOG4105C8Q	Methyl-accepting chemotaxis
CCZ37_06980	ENOG41067TZ	transcriptional regulator, MarR family
CCZ37_06995	ENOG4105C5X	domain protein
CCZ37_07000	ENOG4105EAQ	(twin-arginine translocation) pathway signal
CCZ37_07005	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
CCZ37_07030	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
CCZ37_07035	ENOG4105DKQ	ROK family
CCZ37_07045	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
CCZ37_07050	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
CCZ37_07055	ENOG41090JE	Utilization Protein
CCZ37_07065	ENOG41090AP	transport protein
CCZ37_07070	ENOG4106GFD	transport protein
CCZ37_07080	ENOG4105EHG	Permease protein
CCZ37_07085	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
CCZ37_07090	ENOG4105C72	UPF0176 protein
CCZ37_07100	ENOG4105C8Q	Methyl-accepting chemotaxis
CCZ37_07105	ENOG4107R3K	hydrolase
CCZ37_07115	ENOG4105C5Y	PTS System
CCZ37_07120	ENOG4105D7K	pfkb domain protein
CCZ37_07125	ENOG4105BZU	Histidine kinase
CCZ37_07135	ENOG4108N3W	hemolysin secretion protein
CCZ37_07140	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CCZ37_07145	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CCZ37_07165	ENOG4105E18	UPF0276 protein
CCZ37_07180	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CCZ37_07185	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CCZ37_07195	ENOG4105M4H	endoribonuclease L-psp
CCZ37_07250	ENOG4105DZX	CRISPR-associated protein, Csy2 family
CCZ37_07255	ENOG4105ENG	CRISPR-associated protein, Csy1 family
CCZ37_07265	ENOG4107SV5	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
CCZ37_07305	ENOG4105K44	type iii secretion
CCZ37_07320	ENOG41075IY	surface presentation of antigens protein SpaP
CCZ37_07335	ENOG4108TU9	TRANSCRIPTIONal
CCZ37_07365	ENOG4105D00	flagellar biosynthetic protein flhB
CCZ37_07450	ENOG4108TU9	TRANSCRIPTIONal
CCZ37_07455	ENOG4105BZU	Histidine kinase
CCZ37_07460	ENOG4107ZHV	Transcriptional regulator
CCZ37_07465	ENOG4107104	thymidine kinase
CCZ37_07470	ENOG4105C9M	aspartyl-trna synthetase
CCZ37_07475	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
CCZ37_07480	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
CCZ37_07485	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
CCZ37_07500	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
CCZ37_07505	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
CCZ37_07510	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
CCZ37_07515	ENOG4106371	Methyltransferase
CCZ37_07520	ENOG4107S90	membrAne
CCZ37_07525	ENOG4106WF9	DNA-binding transcriptional regulator TorR
CCZ37_07530	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
CCZ37_07535	ENOG4105ETE	Transcriptional regulator (LacI family
CCZ37_07540	ENOG4105HP8	regulator of competence-specific genes
CCZ37_07560	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
CCZ37_07565	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
CCZ37_07570	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CCZ37_07575	ENOG4105RKX	Protein of unknown function (DUF2498)
CCZ37_07580	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CCZ37_07585	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
CCZ37_07590	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
CCZ37_07595	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CCZ37_07600	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CCZ37_07605	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
CCZ37_07610	ENOG4105VEQ	Cold shock protein
CCZ37_07620	ENOG4108R99	pseudouridine synthase
CCZ37_07625	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CCZ37_07630	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
CCZ37_07645	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CCZ37_07650	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CCZ37_07655	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
CCZ37_07660	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CCZ37_07665	ENOG4107S6Z	Na H antiporter
CCZ37_07670	ENOG4108SAU	DNA-binding protein H-ns
CCZ37_07675	ENOG4107RE1	Inosine-guanosine kinase
CCZ37_07685	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CCZ37_07690	ENOG41075W9	High frequency lysogenization protein HflD homolog
CCZ37_07695	ENOG4107QTF	adenylosuccinate lyase
CCZ37_07700	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
CCZ37_07710	ENOG4105BZU	Histidine kinase
CCZ37_07735	ENOG4105DWU	Membrane
CCZ37_07745	ENOG4105DY8	decarboxylase
CCZ37_07750	ENOG4106KNT	transcriptional regulator
CCZ37_07755	ENOG41090BQ	Glutaredoxin
CCZ37_07765	ENOG4105C8V	SAICAR synthetase
CCZ37_07775	ENOG4107R1I	NAD-dependent malic enzyme
CCZ37_07785	ENOG4107GZ4	SanA protein
CCZ37_07790	ENOG4105C9B	Cysteine desulfurase
CCZ37_07800	ENOG4105BZU	Histidine kinase
CCZ37_07805	ENOG4105C3M	thioredoxin reductase
CCZ37_07810	ENOG4108JJ9	ABC, transporter
CCZ37_07815	ENOG4108JJ8	(ABC) transporter
CCZ37_07820	ENOG4105FE9	pseudouridine synthase
CCZ37_07825	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
CCZ37_07830	ENOG4105DB7	PHP domain protein
CCZ37_07840	ENOG4105CRQ	synthase (Component I)
CCZ37_07845	ENOG4105DDQ	anthranilate synthase
CCZ37_07850	ENOG4108I0Q	anthranilate phosphoribosyltransferase
CCZ37_07855	ENOG4105DK0	Indole-3-glycerol phosphate synthase
CCZ37_07860	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CCZ37_07870	ENOG4105CK2	sodium dicarboxylate symporter
CCZ37_07880	ENOG4107835	probably involved in intracellular septation (By similarity)
CCZ37_07885	ENOG4105NAU	thioesterase Superfamily protein
CCZ37_07890	ENOG4105K9H	YciI-like protein
CCZ37_07900	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
CCZ37_07905	ENOG4105DZ2	Transcriptional regulator
CCZ37_07920	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
CCZ37_07930	ENOG4105CCT	upf0313 protein
CCZ37_07940	ENOG4105RHG	
CCZ37_07950	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CCZ37_07965	ENOG4105E1F	short-chain dehydrogenase reductase
CCZ37_07975	ENOG4105D0M	Protease HtpX homolog
CCZ37_07985	ENOG4105CNU	cell division protein FtsK
CCZ37_07990	ENOG4105EW9	transcriptional regulator AsnC family
CCZ37_07995	ENOG4105DCF	alanine dehydrogenase
CCZ37_08005	ENOG4107R11	Transcriptional regulator
CCZ37_08015	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
CCZ37_08020	ENOG4105CFV	Tetratricopeptide repeat protein
CCZ37_08025	ENOG4105Q4A	inner membrane protein yciS
CCZ37_08030	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CCZ37_08035	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CCZ37_08040	ENOG4105CAT	Cytidine monophosphate kinase
CCZ37_08045	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
CCZ37_08050	ENOG4105EIN	peptidylprolyl cis-trans isomerase
CCZ37_08055	ENOG4105K70	DNA-binding protein
CCZ37_08060	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CCZ37_08065	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CCZ37_08070	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CCZ37_08075	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CCZ37_08090	ENOG4108JP0	extracellular solute-binding protein family 1
CCZ37_08095	ENOG4105CNG	UPF0061 protein
CCZ37_08100	ENOG4105EJQ	L-serine dehydratase
CCZ37_08110	ENOG4105C1J	atp-dependent rna helicase
CCZ37_08120	ENOG4105C94	Transporter
CCZ37_08125	ENOG4105C3R	Methionine synthase
CCZ37_08135	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
CCZ37_08140	ENOG4105DZR	Type I site-specific deoxyribonuclease
CCZ37_08150	ENOG4105EKX	Restriction modification system DNA (Specificity
CCZ37_08155	ENOG4105CVR	type I restriction-modification system
CCZ37_08165	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CCZ37_08170	ENOG4105D9N	nucleoside
CCZ37_08175	ENOG4105EJC	lysr family transcriptional regulator
CCZ37_08180	ENOG4105CVE	Lytic murein transglycosylase
CCZ37_08190	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
CCZ37_08195	ENOG4107QMS	site-determining protein
CCZ37_08200	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
CCZ37_08205	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
CCZ37_08210	ENOG4105CEY	Amp-dependent synthetase and ligase
CCZ37_08215	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
CCZ37_08230	ENOG41072GX	Peptidase M22 Glycoprotease
CCZ37_08235	ENOG4105DVT	helicase
CCZ37_08245	ENOG4105CIY	formyltetrahydrofolate deformylase
CCZ37_08250	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CCZ37_08255	ENOG4105D07	Signal peptide peptidase, SppA
CCZ37_08260	ENOG4105HDK	L-asparaginase
CCZ37_08265	ENOG4105VUT	cytoplasmic protein
CCZ37_08275	ENOG4105E0X	reductase
CCZ37_08285	ENOG4105DSB	aldose 1-epimerase
CCZ37_08290	ENOG4105DHI	Methyltransferase
CCZ37_08305	ENOG4108ZZ3	UPF0260 protein
CCZ37_08310	ENOG4105KRS	Proteinase inhibitor
CCZ37_08315	ENOG4105BZU	Histidine kinase
CCZ37_08320	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CCZ37_08325	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CCZ37_08330	ENOG4107QMP	dna polymerase iii subunits gamma and tau
CCZ37_08335	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CCZ37_08340	ENOG4105WD1	Membrane
CCZ37_08350	ENOG4105I93	response regulator
CCZ37_08355	ENOG4105EJC	lysr family transcriptional regulator
CCZ37_08365	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CCZ37_08370	ENOG4105CHU	acetyl-coa acetyltransferase
CCZ37_08385	ENOG4108AEY	RNA polymerase sigma factor
CCZ37_08395	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
CCZ37_08400	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
CCZ37_08405	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
CCZ37_08410	ENOG4108GAE	asmA family
CCZ37_08415	ENOG4105DBI	uridine monophosphokinase
CCZ37_08420	ENOG4105D1F	ATP-binding protein
CCZ37_08425	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CCZ37_08435	ENOG4108I5U	Uridine phosphorylase
CCZ37_08450	ENOG4105BZU	Histidine kinase
CCZ37_08455	ENOG4108ZAF	Molybdopterin
CCZ37_08460	ENOG4105M00	molybdopterin converting factor, subunit 1
CCZ37_08465	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CCZ37_08470	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
CCZ37_08475	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CCZ37_08480	ENOG4105CHW	UPF0052 protein
CCZ37_08490	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CCZ37_08495	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CCZ37_08505	ENOG4106TD9	Diguanylate cyclase
CCZ37_08530	ENOG4108MNP	Glycoprotein polysaccharide metabolism
CCZ37_08535	ENOG4105C29	acyl-CoA thioesterase
CCZ37_08540	ENOG4108XM1	transcriptional regulator AsnC family
CCZ37_08580	ENOG4105CEY	Amp-dependent synthetase and ligase
CCZ37_08585	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
CCZ37_08590	ENOG4108IPT	Naphthoate synthase
CCZ37_08600	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
CCZ37_08605	ENOG4105E4F	Isochorismate synthase
CCZ37_08615	ENOG4105CHM	Aminotransferase
CCZ37_08620	ENOG4105DK2	UPF0207 protein
CCZ37_08625	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
CCZ37_08640	ENOG4105ERU	peptidase
CCZ37_08645	ENOG4105UBK	short-chain dehydrogenase reductase
CCZ37_08650	ENOG4107R88	Chemotaxis protein (CheV)
CCZ37_08655	ENOG4105DAG	ROK family
CCZ37_08660	ENOG4105CA9	Pyruvate kinase
CCZ37_08665	ENOG4108NRW	Phospholipase, patatin family
CCZ37_08680	ENOG4105C8J	)-transporter
CCZ37_08690	ENOG4105CI1	PTS System
CCZ37_08695	ENOG4105F8V	Hydrolase, tatD family
CCZ37_08700	ENOG4107QRG	dna polymerase iii
CCZ37_08705	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CCZ37_08710	ENOG4105HHA	aminodeoxychorismate lyase
CCZ37_08715	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
CCZ37_08720	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CCZ37_08725	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CCZ37_08730	ENOG4105CHR	reductase
CCZ37_08735	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
CCZ37_08740	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CCZ37_08745	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
CCZ37_08750	ENOG4105VGS	50s ribosomal protein l32
CCZ37_08755	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
CCZ37_08760	ENOG4108UHJ	MAF-like protein
CCZ37_08765	ENOG4105EI2	Pseudouridine synthase
CCZ37_08770	ENOG4105C03	ribonuclease
CCZ37_08780	ENOG4108EKI	Dehydrogenase
CCZ37_08785	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
CCZ37_08790	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CCZ37_08795	ENOG4105DFD	Na H antiporter
CCZ37_08805	ENOG4106V8H	Nucleoid-associated protein
CCZ37_08815	ENOG4105E68	Sulfatase
CCZ37_08825	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
CCZ37_08830	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
CCZ37_08845	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CCZ37_08850	ENOG4105M2J	Glutaredoxin
CCZ37_08855	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CCZ37_08870	ENOG410903C	(LipO)protein
CCZ37_08880	ENOG4108M1T	Cytochrome c-type biogenesis protein
CCZ37_08885	ENOG4107QX9	Thiol disulfide interChange protein
CCZ37_08890	ENOG4105DA4	cytochrome c-type biogenesis protein
CCZ37_08895	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
CCZ37_08905	ENOG41060IM	Heme exporter protein
CCZ37_08910	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
CCZ37_08925	ENOG4108V3W	Chemotaxis protein, CheW
CCZ37_08935	ENOG4107QJE	Chromosome Partitioning Protein
CCZ37_08940	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CCZ37_08950	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
CCZ37_08955	ENOG4108VYJ	response regulator receiver protein
CCZ37_08960	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CCZ37_08965	ENOG4107R21	site-determining protein
CCZ37_08970	ENOG4105FZW	flagellar biosynthesis regulator FlhF
CCZ37_08975	ENOG4105D7B	Flagellar biosynthesis protein flha
CCZ37_08980	ENOG4108BY2	phosphohistidine phosphatase
CCZ37_08985	ENOG4108JQM	Insulinase (Peptidase family M16)
CCZ37_08990	ENOG4106ZCM	YecM protein
CCZ37_08995	ENOG4105C75	arginyL-tRNA synthetase
CCZ37_09015	ENOG4105XFK	Ferrous iron transport protein A
CCZ37_09020	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
CCZ37_09025	ENOG4105NXV	High-affinity zinc uptake system protein
CCZ37_09030	ENOG4105FDK	ABC transporter
CCZ37_09035	ENOG4105FAV	ABC, transporter
CCZ37_09040	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
CCZ37_09045	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
CCZ37_09050	ENOG4105C7S	Dehydrogenase
CCZ37_09055	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
CCZ37_09060	ENOG4105E33	succinate dehydrogenase
CCZ37_09065	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
CCZ37_09070	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
CCZ37_09075	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
CCZ37_09080	ENOG4105BZN	citrate synthase
CCZ37_09085	ENOG4107QNR	UPF0135 protein
CCZ37_09095	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
CCZ37_09100	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
CCZ37_09105	ENOG4105EV9	Alpha Beta Hydrolase
CCZ37_09115	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
CCZ37_09120	ENOG41067MG	lrgb family
CCZ37_09125	ENOG4105VAW	lrga family
CCZ37_09130	ENOG4105CMU	LysR family (Transcriptional regulator
CCZ37_09140	ENOG41090R7	Ferric uptake
CCZ37_09145	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CCZ37_09150	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
CCZ37_09155	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CCZ37_09160	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
CCZ37_09165	ENOG4105Q8W	reductase
CCZ37_09170	ENOG4105MH2	YfcL protein
CCZ37_09175	ENOG4108BPE	-transporting atpase
CCZ37_09180	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CCZ37_09185	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
CCZ37_09190	ENOG4108DG9	Smr protein MutS2
CCZ37_09195	ENOG4105D00	flagellar biosynthetic protein flhB
CCZ37_09200	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
CCZ37_09205	ENOG4105VS8	Flagellar biosynthetic protein fliq
CCZ37_09210	ENOG4105CN7	Flagellar biosynthetic protein FliP
CCZ37_09215	ENOG4105VTB	flagellar biosynthesis protein fliO
CCZ37_09220	ENOG4105DD5	Flagellar motor switch protein
CCZ37_09225	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CCZ37_09245	ENOG4108JIR	Flagellum-specific ATP synthase
CCZ37_09255	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CCZ37_09260	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
CCZ37_09265	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
CCZ37_09270	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CCZ37_09275	ENOG4105BZU	Histidine kinase
CCZ37_09280	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CCZ37_09285	ENOG4105MQ3	flagellar protein FliS
CCZ37_09295	ENOG4107BRV	flagellar capping protein
CCZ37_09300	ENOG41063QE	flagellar protein FlaG
CCZ37_09305	ENOG4105I03	Flagellin
CCZ37_09310	ENOG4105I03	Flagellin
CCZ37_09315	ENOG4105I03	Flagellin
CCZ37_09320	ENOG4105EZR	dyp-type peroxidase family protein
CCZ37_09325	ENOG4105QZU	Inner membrane protein YfeZ
CCZ37_09345	ENOG4105KUZ	arsenate reductase
CCZ37_09350	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CCZ37_09365	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CCZ37_09370	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CCZ37_09380	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CCZ37_09385	ENOG4105C8Q	Methyl-accepting chemotaxis
CCZ37_09400	ENOG4105ERG	peptidase m48, ste24p
CCZ37_09405	ENOG4105K89	arsenate reductase
CCZ37_09410	ENOG4105CS1	NAD(P)H quinone oxidoreductase
CCZ37_09425	ENOG4105C2W	permease
CCZ37_09430	ENOG4108Z66	YbaK ebsC protein
CCZ37_09435	ENOG4105CGH	5'-nucleotidase
CCZ37_09440	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
CCZ37_09445	ENOG41063JG	Transcriptional regulator
CCZ37_09450	ENOG4108YY7	Invasion gene expression up-regulator SirB
CCZ37_09455	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CCZ37_09460	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CCZ37_09465	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
CCZ37_09475	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
CCZ37_09480	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CCZ37_09485	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CCZ37_09490	ENOG4105C3G	gtp-binding protein
CCZ37_09575	ENOG4105I03	Flagellin
CCZ37_09580	ENOG4105I03	Flagellin
CCZ37_09590	ENOG4105DTJ	flagellar hook-associated protein
CCZ37_09600	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
CCZ37_09605	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CCZ37_09610	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CCZ37_09615	ENOG4105CGA	flagellar basal-body rod protein FlgG
CCZ37_09620	ENOG4108KPB	Flagellar basal-body rod protein FlgF
CCZ37_09625	ENOG4105BZE	flagellar hook protein, FlgE
CCZ37_09630	ENOG4105W00	Flagellar hook capping protein
CCZ37_09635	ENOG4108ZC9	flagellar basal-body rod protein flgc
CCZ37_09640	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
CCZ37_09645	ENOG4105BZU	Histidine kinase
CCZ37_09650	ENOG4107R88	Chemotaxis protein (CheV)
CCZ37_09695	ENOG4105UYK	outer membrane protein a
CCZ37_09700	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CCZ37_09705	ENOG4105C59	p-type ATPase
CCZ37_09715	ENOG4105E2D	ec 3.2.1.52
CCZ37_09735	ENOG4105FE9	pseudouridine synthase
CCZ37_09740	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CCZ37_09745	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CCZ37_09750	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
CCZ37_09755	ENOG4105E7A	Glutamine amidotransferase
CCZ37_09760	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
CCZ37_09765	ENOG4107QPN	acyl-Coa dehydrogenase
CCZ37_09775	ENOG4108JDX	DNA polymerase iii, epsilon subunit
CCZ37_09780	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CCZ37_09785	ENOG4105D1A	Methyltransferase
CCZ37_09790	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CCZ37_09795	ENOG4105E9H	Lytic Murein transglycosylase
CCZ37_09810	ENOG4108YZA	Nitrogen regulatory protein pii
CCZ37_09815	ENOG4105PY6	Phenolic acid decarboxylase
CCZ37_09820	ENOG4105N7H	Cytochrome
CCZ37_09825	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CCZ37_09830	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
CCZ37_09835	ENOG4105C0B	DNA polymerase III (alpha subunit)
CCZ37_09840	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CCZ37_09845	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CCZ37_09850	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CCZ37_09855	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CCZ37_09860	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CCZ37_09865	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
CCZ37_09875	ENOG4105DZP	Membrane-associated zinc metalloprotease
CCZ37_09880	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CCZ37_09885	ENOG4105KNE	Phosphatidate cytidylyltransferase
CCZ37_09890	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CCZ37_09895	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CCZ37_09900	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CCZ37_09905	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CCZ37_09910	ENOG4105CE9	30S ribosomal protein S2
CCZ37_09915	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
CCZ37_09925	ENOG4108T8E	UPF0325 protein
CCZ37_09930	ENOG4108ZAI	phosphatidylglycerophosphatase a
CCZ37_09935	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
CCZ37_09940	ENOG4107YIM	Involved in the transcription termination process (By similarity)
CCZ37_09945	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CCZ37_09960	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CCZ37_09965	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
CCZ37_09970	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CCZ37_09975	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CCZ37_09980	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
CCZ37_09985	ENOG4108DJV	Fermentation respiration switch protein
CCZ37_09990	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
CCZ37_09995	ENOG4105C7N	Xanthine uracil vitamin C permease
CCZ37_10000	ENOG4105CIN	aminoacyl-histidine dipeptidase
CCZ37_10005	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
CCZ37_10010	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
CCZ37_10020	ENOG4105C8J	)-transporter
CCZ37_10035	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CCZ37_10045	ENOG4105CJ2	(LipO)protein
CCZ37_10050	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
CCZ37_10055	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CCZ37_10060	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CCZ37_10065	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CCZ37_10070	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CCZ37_10075	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CCZ37_10080	ENOG4105M85	Bola protein
CCZ37_10085	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
CCZ37_10095	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CCZ37_10100	ENOG4105EYM	Major Facilitator superfamily
CCZ37_10110	ENOG4105K6V	RNA polymerase
CCZ37_10125	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
CCZ37_10130	ENOG4105C9B	Cysteine desulfurase
CCZ37_10135	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
CCZ37_10140	ENOG4105CUZ	uba thif-type nad fad binding protein
CCZ37_10145	ENOG4105CA3	membrane-bound lytic murein transglycosylase
CCZ37_10155	ENOG4107QZM	n-acetylglutamate synthase
CCZ37_10165	ENOG4107QYX	exodeoxyribonuclease v alpha
CCZ37_10170	ENOG4107QKA	exodeoxyribonuclease V beta
CCZ37_10175	ENOG4105DSY	exodeoxyribonuclease V, gamma
CCZ37_10190	ENOG4105X2V	dna damage-inducible protein
CCZ37_10195	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
CCZ37_10225	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CCZ37_10235	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
CCZ37_10245	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
CCZ37_10255	ENOG4105EAC	phosphoserine phosphatase
CCZ37_10265	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
CCZ37_10270	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
CCZ37_10275	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
CCZ37_10285	ENOG4105D9N	nucleoside
CCZ37_10290	ENOG4105EYA	deoxyribonuclease
CCZ37_10295	ENOG4105D1Q	UPF0246 protein
CCZ37_10300	ENOG4105BZG	amino acid carrier protein
CCZ37_10315	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
CCZ37_10320	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
CCZ37_10325	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
CCZ37_10330	ENOG4105D98	threonine synthase
CCZ37_10335	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
CCZ37_10355	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
CCZ37_10360	ENOG41065U4	response regulator
CCZ37_10365	ENOG4105BZU	Histidine kinase
CCZ37_10370	ENOG4105N5T	Radical SAM Protein
CCZ37_10385	ENOG4105CBC	glutamate synthase
CCZ37_10390	ENOG4105BZ8	glutamate synthase
CCZ37_10400	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
CCZ37_10410	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
CCZ37_10415	ENOG4105EN6	Membrane
CCZ37_10420	ENOG4105EJ9	Membrane
CCZ37_10435	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CCZ37_10440	ENOG4107RRE	RNA-directed DNA polymerase
CCZ37_10450	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CCZ37_10455	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CCZ37_10460	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CCZ37_10465	ENOG4105M6F	mutator MutT protein
CCZ37_10470	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CCZ37_10480	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CCZ37_10485	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CCZ37_10490	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
CCZ37_10495	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
CCZ37_10500	ENOG4105DFU	Cell wall formation (By similarity)
CCZ37_10505	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CCZ37_10515	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CCZ37_10520	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CCZ37_10525	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
CCZ37_10530	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CCZ37_10535	ENOG4105CJN	penicillin-binding protein
CCZ37_10540	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
CCZ37_10545	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CCZ37_10555	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
CCZ37_10560	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
CCZ37_10565	ENOG41082RQ	UPF0102 protein
CCZ37_10570	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
CCZ37_10575	ENOG4105W4M	Transport-associated protein
CCZ37_10580	ENOG4105KB2	stringent starvation protein b
CCZ37_10585	ENOG4107MKT	Stringent starvation protein a
CCZ37_10590	ENOG4105EIX	cytochrome c1
CCZ37_10595	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CCZ37_10600	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CCZ37_10605	ENOG4108UJD	30S ribosomal protein S9
CCZ37_10610	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
CCZ37_10620	ENOG4105D6Z	AFG1 family ATPase
CCZ37_10625	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
CCZ37_10630	ENOG4105C0H	protease
CCZ37_10635	ENOG4105C0H	protease
CCZ37_10640	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CCZ37_10645	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CCZ37_10650	ENOG4105IPS	esterase
CCZ37_10655	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
CCZ37_10660	ENOG4108SX3	cytoplasmic protein
CCZ37_10665	ENOG41087AY	ADP-Ribose pyrophosphatase
CCZ37_10670	ENOG4105DFG	type I secretion outer membrane protein
CCZ37_10680	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
CCZ37_10685	ENOG4105C8Q	Methyl-accepting chemotaxis
CCZ37_10690	ENOG4105I7R	Adenylate cyclase
CCZ37_10695	ENOG4107IX6	phosphate transport regulator
CCZ37_10700	ENOG4105CJ3	phosphate transporter
CCZ37_10705	ENOG4106MWK	domain protein
CCZ37_10720	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CCZ37_10725	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CCZ37_10730	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CCZ37_10735	ENOG4105DXN	mazG family
CCZ37_10740	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CCZ37_10745	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CCZ37_10750	ENOG4105BZU	Histidine kinase
CCZ37_10755	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
CCZ37_10760	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
CCZ37_10765	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
CCZ37_10770	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
CCZ37_10775	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
CCZ37_10780	ENOG4105C3F	Signal peptidase i
CCZ37_10785	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CCZ37_10790	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
CCZ37_10805	ENOG4105EMN	RNA polymerase sigma factor
CCZ37_10810	ENOG4108IYU	L-aspartate oxidase
CCZ37_10820	ENOG4105Y75	tpr repeat protein
CCZ37_10825	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
CCZ37_10840	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
CCZ37_10845	ENOG4105D0A	hydroxylase
CCZ37_10855	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
CCZ37_10865	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
CCZ37_10870	ENOG4105E66	phosphoriboisomerase A
CCZ37_10875	ENOG4108JQ1	Dehydrogenase
CCZ37_10880	ENOG4108ZP8	Acetolactate synthase small subunit
CCZ37_10885	ENOG4105C7K	acetolactate synthase
CCZ37_10890	ENOG4108IQE	Amp-dependent synthetase and ligase
CCZ37_10895	ENOG41064T2	transcriptional regulator, lysR family
CCZ37_10910	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CCZ37_10920	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CCZ37_10925	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CCZ37_11025	ENOG4108K5H	permease YjgP YjgQ family protein
CCZ37_11030	ENOG4108M8S	permease YjgP YjgQ family protein
CCZ37_11035	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CCZ37_11040	ENOG4105MYG	DNA polymerase iii, chi subunit
CCZ37_11045	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
CCZ37_11050	ENOG4105D3G	Pseudouridine synthase
CCZ37_11055	ENOG4105K3M	)-transporter
CCZ37_11060	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
CCZ37_11070	ENOG4108IAB	Phoh family
CCZ37_11075	ENOG4105DBV	ornithine carbamoyltransferase
CCZ37_11080	ENOG4105CXT	aspartate transcarbamylase
CCZ37_11085	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
CCZ37_11090	ENOG4105KME	endoribonuclease L-psp
CCZ37_11095	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
CCZ37_11100	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CCZ37_11105	ENOG4105VFK	BolA family
CCZ37_11115	ENOG4105E3I	toluene tolerance
CCZ37_11120	ENOG4107PE3	Mammalian cell entry related domain protein
CCZ37_11125	ENOG4105CY3	ABC transporter, permease
CCZ37_11130	ENOG4105DHJ	ABC, transporter
CCZ37_11140	ENOG4105C2X	Arabinose 5-phosphate isomerase
CCZ37_11145	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
CCZ37_11155	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
CCZ37_11160	ENOG4108IUZ	ABC transporter
CCZ37_11165	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CCZ37_11170	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
CCZ37_11175	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
CCZ37_11185	ENOG41080Z8	PHOSPHOCARRIER protein
CCZ37_11190	ENOG4105CJW	magnesium transporter
CCZ37_11195	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
CCZ37_11200	ENOG4105N42	UPF0307 protein
CCZ37_11205	ENOG4107T0D	ABC, transporter
CCZ37_11210	ENOG4106SMU	thiamine transporter membrane protein
CCZ37_11215	ENOG4105DP9	ABC transporter
CCZ37_11220	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
CCZ37_11225	ENOG4105DFU	Cell wall formation (By similarity)
CCZ37_11230	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CCZ37_11235	ENOG4105F0N	pyrophosphate phospho-hydrolase
CCZ37_11240	ENOG41066HZ	AIG2-like family
CCZ37_11245	ENOG4105MA0	exported protein
CCZ37_11250	ENOG4105CFU	surface antigen
CCZ37_11255	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CCZ37_11260	ENOG4108UUE	Transcriptional regulator
CCZ37_11295	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
CCZ37_11300	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
CCZ37_11305	ENOG4105C11	sulfate adenylyltransferase), subunit 2
CCZ37_11310	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CCZ37_11315	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
CCZ37_11325	ENOG4105C1J	atp-dependent rna helicase
CCZ37_11330	ENOG4107YB6	acetyltransferase, (GNAT) family
CCZ37_11335	ENOG4108UBT	opacity-associated protein
CCZ37_11340	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CCZ37_11345	ENOG4108ZT0	50S ribosomal protein l17
CCZ37_11350	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CCZ37_11355	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CCZ37_11360	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CCZ37_11365	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CCZ37_11375	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CCZ37_11380	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CCZ37_11385	ENOG4105VPB	50S ribosomal protein L30
CCZ37_11390	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CCZ37_11400	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CCZ37_11405	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CCZ37_11410	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CCZ37_11415	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CCZ37_11425	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CCZ37_11430	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CCZ37_11435	ENOG41083MP	50s ribosomal protein l29
CCZ37_11440	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CCZ37_11445	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CCZ37_11450	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CCZ37_11455	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CCZ37_11460	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CCZ37_11465	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CCZ37_11470	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CCZ37_11475	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CCZ37_11480	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
CCZ37_11485	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CCZ37_11490	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CCZ37_11495	ENOG4108UV7	flagellar protein motX
CCZ37_11505	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CCZ37_11510	ENOG4105D44	asparaginase
CCZ37_11515	ENOG4108YZY	peptidylprolyl cis-trans isomerase
CCZ37_11520	ENOG4105VKU	nucleicacid-binding protein
CCZ37_11530	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
CCZ37_11535	ENOG4105C5H	ABC transporter
CCZ37_11545	ENOG4105DNZ	Alpha Beta Hydrolase
CCZ37_11550	ENOG4105YP7	UPF0270 protein
CCZ37_11555	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
CCZ37_11560	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
CCZ37_11570	ENOG4105C26	Dehydrogenase
CCZ37_11585	ENOG4105DDQ	anthranilate synthase
CCZ37_11635	ENOG4107SCK	Monooxygenase
CCZ37_11645	ENOG4105CR8	Transcriptional regulator
CCZ37_11660	ENOG4105C31	Tryptophanyl-tRNA synthetase
CCZ37_11665	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CCZ37_11670	ENOG4105DJV	ribulose-phosphate 3-epimerase
CCZ37_11675	ENOG4105DFE	Dna adenine methylase
CCZ37_11685	ENOG4105D49	3-dehydroquinate synthase
CCZ37_11690	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
CCZ37_11695	ENOG4105E4G	Type IV pilus
CCZ37_11720	ENOG4108JQC	penicillin-binding protein 1A
CCZ37_11725	ENOG4105C5Q	Transcriptional regulator
CCZ37_11730	ENOG4105EHV	domain protein
CCZ37_11735	ENOG4107QN2	dihydrolipoyl dehydrogenase
CCZ37_11745	ENOG4105CH7	arginosuccinase
CCZ37_11750	ENOG4105CDH	Citrulline--aspartate ligase
CCZ37_11755	ENOG4105CAS	nag kinase
CCZ37_11760	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
CCZ37_11765	ENOG4105CWC	Acetylornithine deacetylase
CCZ37_11770	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
CCZ37_11780	ENOG4105D7W	serine acetyltransferase
CCZ37_11785	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CCZ37_11790	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
CCZ37_11795	ENOG4107YZP	Rhodanese domain protein
CCZ37_11800	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
CCZ37_11815	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
CCZ37_11820	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
CCZ37_11825	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CCZ37_11830	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
CCZ37_11845	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CCZ37_11850	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CCZ37_11875	ENOG4105CP7	Triose-phosphate isomerase
CCZ37_11880	ENOG4107QMU	Mate efflux family protein
CCZ37_11885	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
CCZ37_11890	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
CCZ37_11895	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
CCZ37_11900	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
CCZ37_11910	ENOG4105ETE	Transcriptional regulator (LacI family
CCZ37_11915	ENOG4105C25	Primosomal protein n'
CCZ37_11920	ENOG4105VFB	Binds the 23S rRNA (By similarity)
CCZ37_11925	ENOG4105C6K	Malic enzyme
CCZ37_11930	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
CCZ37_11935	ENOG4105C28	cystathionine
CCZ37_11940	ENOG4105CFH	Aspartokinase
CCZ37_11945	ENOG4105SYT	Methylenetetrahydrofolate reductase
CCZ37_11950	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
CCZ37_11955	ENOG4105CBT	Fructose-1,6-bisphosphatase
CCZ37_11960	ENOG4105CTQ	phosphohexokinase
CCZ37_11965	ENOG41076HS	cation diffusion facilitator family transporter
CCZ37_11975	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CCZ37_11980	ENOG4105E0F	Histidine kinase
CCZ37_11985	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
CCZ37_11990	ENOG4105VEQ	Cold shock protein
CCZ37_12000	ENOG4105BZU	Histidine kinase
CCZ37_12005	ENOG4108IJ0	Aspartate ammonia-lyase
CCZ37_12010	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
CCZ37_12015	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
CCZ37_12025	ENOG4105CEU	Arginine dihydrolase
CCZ37_12035	ENOG4105DBV	ornithine carbamoyltransferase
CCZ37_12045	ENOG4105CXT	aspartate transcarbamylase
CCZ37_12050	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
CCZ37_12055	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
CCZ37_12060	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
CCZ37_12070	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
CCZ37_12080	ENOG4107QN1	sodium solute
CCZ37_12085	ENOG4105BZU	Histidine kinase
CCZ37_12090	ENOG4105D8G	Major Facilitator superfamily
CCZ37_12110	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
CCZ37_12115	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
CCZ37_12120	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CCZ37_12130	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CCZ37_12135	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
CCZ37_12145	ENOG4105CXN	decarboxylase
CCZ37_12150	ENOG4105D5Q	Arginine ornithine antiporter
CCZ37_12155	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
CCZ37_12160	ENOG4108M3R	transcriptional activator CadC
CCZ37_12165	ENOG4105W1Y	Transcriptional regulator
CCZ37_12170	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CCZ37_12185	ENOG4105K70	DNA-binding protein
CCZ37_12200	ENOG4105R2J	Conserved Protein
CCZ37_12205	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
CCZ37_12210	ENOG4105CUY	Mechanosensitive ion channel
CCZ37_12215	ENOG4105C8Q	Methyl-accepting chemotaxis
CCZ37_12220	ENOG4105CY0	Metallo-Beta-Lactamase
CCZ37_12225	ENOG4105ESV	Glycosyl transferase, family 4
CCZ37_12230	ENOG41074DU	domain protein
CCZ37_12235	ENOG4108P2H	Inner membrane protein YjiG
CCZ37_12240	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CCZ37_12255	ENOG4106ECQ	phosphomannomutase
CCZ37_12260	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
CCZ37_12275	ENOG4108I69	Glycosyl transferases group 1
CCZ37_12325	ENOG4107ZF2	Phosphatase
CCZ37_12330	ENOG4105DAY	polysaccharide export protein
CCZ37_12345	ENOG4108MDC	(LipO)protein
CCZ37_12355	ENOG4105E3R	(LipO)protein
CCZ37_12365	ENOG4105D3Q	Sugar transferase
CCZ37_12385	ENOG4105FGF	GDP-mannose mannosyl hydrolase
CCZ37_12390	ENOG410600T	transposase
CCZ37_12425	ENOG4105MFV	ABC-2 type transporter
CCZ37_12430	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CCZ37_12435	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
CCZ37_12440	ENOG4107QKV	phosphomannomutase
CCZ37_12445	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
CCZ37_12450	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
CCZ37_12460	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
CCZ37_12465	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
CCZ37_12470	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
CCZ37_12495	ENOG4105XA0	heptosyltransferase ii
CCZ37_12500	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
CCZ37_12505	ENOG4105EQK	-acetyltransferase
CCZ37_12515	ENOG4105F0R	Cytidylyltransferase
CCZ37_12525	ENOG4105C2X	Arabinose 5-phosphate isomerase
CCZ37_12530	ENOG4108UW5	maltose o-acetyltransferase
CCZ37_12535	ENOG4105D2T	synthase
CCZ37_12540	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
CCZ37_12545	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CCZ37_12555	ENOG4105E68	Sulfatase
CCZ37_12565	ENOG41080IJ	Diacylglycerol kinase
CCZ37_12570	ENOG4105DKP	glycosyl transferase, family 9
CCZ37_12575	ENOG4106WTF	Glycosyl transferase, family 2
CCZ37_12580	ENOG4105M5K	heptosyltransferase
CCZ37_12585	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CCZ37_12590	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
CCZ37_12600	ENOG4105W0E	50S ribosomal protein L33
CCZ37_12605	ENOG4105KDC	50s ribosomal protein l28
CCZ37_12610	ENOG4105W5Q	DNA repair protein (RadC
CCZ37_12615	ENOG4105C8Q	Methyl-accepting chemotaxis
CCZ37_12620	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
CCZ37_12625	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
CCZ37_12630	ENOG4105D1S	lipid A biosynthesis
CCZ37_12635	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
CCZ37_12640	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CCZ37_12645	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
CCZ37_12650	ENOG4105DSJ	YicC domain protein
CCZ37_12705	ENOG4105CFI	type iii restriction protein res subunit
CCZ37_12730	ENOG4107RAN	Peptidase, M16
CCZ37_12745	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CCZ37_12750	ENOG4105FR1	rard protein
CCZ37_12755	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CCZ37_12765	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
CCZ37_12770	ENOG4105C4R	Atp-dependent dna helicase
CCZ37_12775	ENOG4105DGW	oligopeptidase A
CCZ37_12780	ENOG4105D6S	protein involved in catabolism of external DNA
CCZ37_12785	ENOG4105DC8	reductase
CCZ37_12800	ENOG4105EFX	secretion protein, HlyD family
CCZ37_12815	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
CCZ37_12825	ENOG4105DY2	Paraquat-inducible protein b
CCZ37_12830	ENOG4105F1S	paraquat-inducible protein a
CCZ37_12845	ENOG4108VYJ	response regulator receiver protein
CCZ37_12860	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CCZ37_12865	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CCZ37_12905	ENOG4105MPD	Cytochrome
CCZ37_12910	ENOG4105C4R	Atp-dependent dna helicase
CCZ37_12915	ENOG4107Z3H	Transcriptional regulator, TetR family
CCZ37_12920	ENOG410624X	efflux transporter, rnd family, mfp subunit
CCZ37_12925	ENOG4105BZS	acriflavin resistance protein
CCZ37_12930	ENOG4105W0Z	cytoplasmic protein
CCZ37_12935	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CCZ37_12940	ENOG4105EMY	transcriptional regulator
CCZ37_12945	ENOG4105D4P	Coproporphyrinogen iii oxidase
CCZ37_12950	ENOG4105XCT	Protein of unknown function (DUF2489)
CCZ37_12955	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
CCZ37_12970	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
CCZ37_12975	ENOG4105C2M	dna polymerase I
CCZ37_12980	ENOG4105D52	delta-aminolevulinic acid dehydratase
CCZ37_12995	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
CCZ37_13000	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
CCZ37_13005	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
CCZ37_13010	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
CCZ37_13015	ENOG4105JC1	sterol-binding domain protein
CCZ37_13020	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CCZ37_13025	ENOG4105CGY	Dna recombination protein
CCZ37_13030	ENOG4108TVT	permease
CCZ37_13035	ENOG4105BZU	Histidine kinase
CCZ37_13040	ENOG4105CBX	hi0933 family
CCZ37_13050	ENOG4108V6B	universal stress protein B
CCZ37_13055	ENOG41090A1	ferritin
CCZ37_13060	ENOG4108M6U	Universal stress protein A
CCZ37_13065	ENOG4105EMK	carboxylate amino acid amine transporter
CCZ37_13075	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
CCZ37_13080	ENOG4108VVK	transcriptional Regulator, AsnC
CCZ37_13090	ENOG4105CNH	Multidrug resistance protein MdtL
CCZ37_13095	ENOG4105G2Y	Transcriptional regulator
CCZ37_13100	ENOG4105DC7	peptidase M24
CCZ37_13100	ENOG4105DC7	peptidase M24
CCZ37_13105	ENOG4105D41	biosynthesis protein thiH
CCZ37_13110	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CCZ37_13115	ENOG4105WHD	thiamine biosynthesis protein ThiS
CCZ37_13120	ENOG4105D06	uba thif-type nad fad binding protein
CCZ37_13125	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CCZ37_13130	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
CCZ37_13135	ENOG4105WMR	Protein CrcB homolog
CCZ37_13185	ENOG4108RR8	protoporphyrinogen oxidase
CCZ37_13190	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
CCZ37_13195	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
CCZ37_13200	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CCZ37_13205	ENOG4105CHU	acetyl-coa acetyltransferase
CCZ37_13210	ENOG4105F52	Transcriptional regulator
CCZ37_13215	ENOG4105CZQ	inner membrane transport protein YdhC
CCZ37_13220	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CCZ37_13225	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CCZ37_13230	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CCZ37_13235	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CCZ37_13240	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CCZ37_13245	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CCZ37_13250	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CCZ37_13255	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CCZ37_13260	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
CCZ37_13265	ENOG410684E	atp synthase
CCZ37_13270	ENOG4105FA0	parb-like partition protein
CCZ37_13275	ENOG4107QJE	Chromosome Partitioning Protein
CCZ37_13280	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CCZ37_13285	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
CCZ37_13290	ENOG4105QTB	Flavodoxin
CCZ37_13295	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CCZ37_13300	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CCZ37_13305	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CCZ37_13310	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
CCZ37_13320	ENOG4105CDA	abc transporter atp-binding protein
CCZ37_13325	ENOG4105E5Q	amino acid AbC transporter
CCZ37_13335	ENOG4108JJA	ABC, transporter
CCZ37_13360	ENOG4105C8Q	Methyl-accepting chemotaxis
CCZ37_13385	ENOG4108V3W	Chemotaxis protein, CheW
CCZ37_13390	ENOG4108V3W	Chemotaxis protein, CheW
CCZ37_13395	ENOG4105CBS	Chea signal transduction histidine kinase
CCZ37_13400	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CCZ37_13410	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
CCZ37_13415	ENOG4107RUE	extracellular solute-binding protein family 1
CCZ37_13420	ENOG4106RMF	ParB family
CCZ37_13455	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
CCZ37_13460	ENOG4105C44	Serine transporter
CCZ37_13490	ENOG4105HEI	LysR family (Transcriptional regulator
CCZ37_13495	ENOG4108RYK	Nad-dependent epimerase dehydratase
CCZ37_13505	ENOG410901E	Membrane
CCZ37_13525	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CCZ37_13550	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
CCZ37_13560	ENOG4105DR5	peptidase
CCZ37_13565	ENOG4105CTS	PTS system mannitol-specific
CCZ37_13570	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
CCZ37_13575	ENOG4105E61	Mannitol repressor protein
CCZ37_13580	ENOG4105CK2	sodium dicarboxylate symporter
CCZ37_13585	ENOG4108VGI	doxx family
CCZ37_13595	ENOG4105J12	Multidrug resistance protein mdtN
CCZ37_13600	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
CCZ37_13610	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
CCZ37_13615	ENOG41082J7	Rhodanese domain protein
CCZ37_13630	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CCZ37_13640	ENOG4105F38	ABC transporter, permease
CCZ37_13660	ENOG4105C1J	atp-dependent rna helicase
CCZ37_13670	ENOG4107VXZ	Hydrolase
CCZ37_13680	ENOG41076CZ	activating enzyme
CCZ37_13685	ENOG4105G0K	glycine radical enzyme YjjI family
CCZ37_13695	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
CCZ37_13700	ENOG4108WUH	Transcriptional regulator, TetR family
CCZ37_13715	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CCZ37_13725	ENOG4105D3G	Pseudouridine synthase
CCZ37_13780	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CCZ37_13785	ENOG4108JUB	Transcriptional regulator
CCZ37_13810	ENOG4105CS6	Rhs element vgr protein
CCZ37_13825	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
CCZ37_13830	ENOG4105C2J	ABC transporter
CCZ37_13835	ENOG4105CNN	ABC, transporter
CCZ37_13840	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
CCZ37_13845	ENOG4108RVA	ribokinase
CCZ37_13850	ENOG4105ETE	Transcriptional regulator (LacI family
CCZ37_13875	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
CCZ37_13885	ENOG4105DAN	ATP-dependent protease
CCZ37_13910	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
CCZ37_13915	ENOG4105PGM	cation diffusion facilitator family transporter
CCZ37_13925	ENOG4108V1U	phospholipid-binding protein
CCZ37_13960	ENOG4105DMF	Dehydrogenase
CCZ37_13965	ENOG4105DAA	L-lactate
CCZ37_13970	ENOG4105CC0	LysR family Transcriptional regulator
CCZ37_13975	ENOG410620I	Diguanylate cyclase
CCZ37_13985	ENOG4105C7K	acetolactate synthase
CCZ37_13990	ENOG4107FQX	Alpha-acetolactate decarboxylase
CCZ37_14000	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
CCZ37_14005	ENOG4105CXY	transporter
CCZ37_14010	ENOG4108M1A	Chitin-binding protein
CCZ37_14020	ENOG4105D4Y	metalloprotease
CCZ37_14030	ENOG4108HK0	-acetyltransferase
CCZ37_14040	ENOG4106KTS	Inner membrane protein yeaI
CCZ37_14050	ENOG4105DWD	nucleoside recognition domain protein
CCZ37_14055	ENOG4105CHH	sulfate transporter
CCZ37_14065	ENOG4105DR5	peptidase
CCZ37_14075	ENOG4105EQ2	LysR family Transcriptional regulator
CCZ37_14080	ENOG4105E5M	Multidrug resistance protein D
CCZ37_14100	ENOG4108SXK	Transporter Drug Metabolite Exporter family
CCZ37_14110	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
CCZ37_14120	ENOG4105DRP	amino acid AbC transporter
CCZ37_14125	ENOG4106TNF	Periplasmic binding protein
CCZ37_14130	ENOG4105E5Q	amino acid AbC transporter
CCZ37_14140	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CCZ37_14150	ENOG4105NBK	UPF0345 protein
CCZ37_14160	ENOG4105EUB	pirin domain protein
CCZ37_14170	ENOG4108K0B	C-di-gmp phosphodiesterase
CCZ37_14185	ENOG4105BZU	Histidine kinase
CCZ37_14200	ENOG4106TD9	Diguanylate cyclase
CCZ37_14205	ENOG4105MSB	protein, conserved in bacteria
CCZ37_14210	ENOG4107R88	Chemotaxis protein (CheV)
CCZ37_14215	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
CCZ37_14220	ENOG41086KC	Transcriptional regulator
CCZ37_14225	ENOG4108IJ9	(ABC) transporter
CCZ37_14235	ENOG4107FKK	extracellular solute-binding protein family 1
CCZ37_14240	ENOG4105D56	permease protein
CCZ37_14245	ENOG4105EG2	ABC transporter, permease
CCZ37_14275	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
CCZ37_14280	ENOG4105EKE	dihydroorotase
CCZ37_14285	ENOG4105QVC	MOSC domain-containing protein
CCZ37_14290	ENOG4105D9N	nucleoside
CCZ37_14295	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
CCZ37_14305	ENOG4108JUA	Transcriptional regulator
CCZ37_14310	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
CCZ37_14315	ENOG4108VWS	Yaeq family
CCZ37_14320	ENOG4105VEQ	Cold shock protein
CCZ37_14345	ENOG4105C5I	Dehydrogenase
CCZ37_14350	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CCZ37_14380	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
CCZ37_14420	ENOG4105BZ1	(ABC) transporter
CCZ37_14425	ENOG4105BZ1	(ABC) transporter
CCZ37_14445	ENOG4105C94	Transporter
CCZ37_14450	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
CCZ37_14475	ENOG4105C0W	non-ribosomal peptide synthetase
CCZ37_14480	ENOG4105EYM	Major Facilitator superfamily
CCZ37_14485	ENOG4107ZSV	Receptor
CCZ37_14490	ENOG4105ID8	Transcriptional regulator, ARAC family
CCZ37_14495	ENOG4108W3Q	Transcriptional regulator
CCZ37_14505	ENOG4105BZU	Histidine kinase
CCZ37_14520	ENOG4105CHH	sulfate transporter
CCZ37_14525	ENOG41082YX	Transcriptional regulator, arsr family
CCZ37_14530	ENOG4105D6J	arsenicaL-resistance protein
CCZ37_14535	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
CCZ37_14540	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CCZ37_14550	ENOG4105C8U	phosphate abc transporter
CCZ37_14560	ENOG41082YX	Transcriptional regulator, arsr family
CCZ37_14565	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CCZ37_14585	ENOG4105CPI	Metal Dependent Phosphohydrolase
CCZ37_14600	ENOG4105CXY	transporter
CCZ37_14605	ENOG4105BZU	Histidine kinase
CCZ37_14610	ENOG4108KX4	response regulator
CCZ37_14615	ENOG4105CXY	transporter
CCZ37_14625	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
CCZ37_14630	ENOG4105EXG	Transcriptional regulator
CCZ37_14635	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CCZ37_14640	ENOG4105CPQ	Dehydrogenase
CCZ37_14655	ENOG4105CPQ	Dehydrogenase
CCZ37_14695	ENOG4108RPX	mosc domain containing protein
CCZ37_14700	ENOG4105CSW	GntR family transcriptional regulator
CCZ37_14710	ENOG4105D4Y	metalloprotease
CCZ37_14715	ENOG4105VRT	cytoplasmic protein
CCZ37_14720	ENOG4105N1F	Hnh endonuclease
CCZ37_14725	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
CCZ37_14760	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CCZ37_14780	ENOG4105C8Q	Methyl-accepting chemotaxis
CCZ37_14810	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
CCZ37_14815	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
CCZ37_14825	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
CCZ37_14830	ENOG4108JPW	Aminotransferase
CCZ37_14835	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
CCZ37_14840	ENOG4105CZK	Aspartate kinase
CCZ37_14855	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
CCZ37_14860	ENOG4105CYW	agmatinase
CCZ37_14865	ENOG4105C8Q	Methyl-accepting chemotaxis
CCZ37_14880	ENOG4105BZU	Histidine kinase
CCZ37_14885	ENOG4107RE1	Inosine-guanosine kinase
CCZ37_14900	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CCZ37_14910	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CCZ37_14925	ENOG4105RKW	reductase (By
CCZ37_14935	ENOG4108I0Y	(ABC) transporter
CCZ37_14940	ENOG4105CV6	ABC transporter, permease
CCZ37_14960	ENOG4105E7W	lamb ycsf family protein
CCZ37_14965	ENOG4105CMR	udp-glucose 4-epimerase
CCZ37_14970	ENOG4105E0U	tyrosine-specific transport protein
CCZ37_14975	ENOG4105C1J	atp-dependent rna helicase
CCZ37_14985	ENOG4105C5W	Aldolase
CCZ37_15000	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
CCZ37_15035	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
CCZ37_15045	ENOG4107QZF	nitrite reductase NADPH large subunit
CCZ37_15050	ENOG4105WZK	nitrite reductase NADPH small subunit
CCZ37_15060	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CCZ37_15065	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CCZ37_15075	ENOG4105VXR	cytoplasmic protein
CCZ37_15085	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CCZ37_15090	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
CCZ37_15095	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
CCZ37_15100	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
CCZ37_15105	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
CCZ37_15110	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
CCZ37_15120	ENOG41090HJ	UPF0265 protein
CCZ37_15130	ENOG4108YXG	UPF0502 protein
CCZ37_15135	ENOG41082IR	Excinuclease ABC C subunit domain protein
CCZ37_15145	ENOG4108QGH	periplasmic
CCZ37_15150	ENOG4105BZU	Histidine kinase
CCZ37_15160	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
CCZ37_15180	ENOG4105EM2	membrane
CCZ37_15185	ENOG41088T4	Helicase IV
CCZ37_15190	ENOG4108Z5K	methylglyoxal synthase
CCZ37_15195	ENOG4108SV3	Tmao reductase system periplasmic protein tort
CCZ37_15200	ENOG4105BZU	Histidine kinase
CCZ37_15205	ENOG4105CA9	Pyruvate kinase
CCZ37_15210	ENOG4105CXY	transporter
CCZ37_15220	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
CCZ37_15230	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
CCZ37_15235	ENOG4108I6A	alcohol dehydrogenase
CCZ37_15240	ENOG4105CF7	AraC family transcriptional regulator
CCZ37_15250	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
CCZ37_15255	ENOG4105BZU	Histidine kinase
CCZ37_15265	ENOG4105WXI	Bacterial OB fold (BOF) protein
CCZ37_15270	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CCZ37_15275	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
CCZ37_15280	ENOG4105E0C	molybdate abc transporter
CCZ37_15285	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
CCZ37_15305	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CCZ37_15320	ENOG4105BZU	Histidine kinase
CCZ37_15325	ENOG4105BZU	Histidine kinase
CCZ37_15330	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CCZ37_15345	ENOG41080HT	Transcriptional regulator, arsr family
CCZ37_15385	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
CCZ37_15390	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
CCZ37_15395	ENOG4105CGF	Aromatic amino acid aminotransferase
CCZ37_15400	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
CCZ37_15415	ENOG4105E43	Extracellular solute-binding protein, family 5
CCZ37_15420	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
CCZ37_15425	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
CCZ37_15430	ENOG4108JQ5	ABC transporter
CCZ37_15440	ENOG4105DS1	cytochrome b561
CCZ37_15445	ENOG4108YYC	ycei family
CCZ37_15450	ENOG4108N3W	hemolysin secretion protein
CCZ37_15455	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CCZ37_15475	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
CCZ37_15485	ENOG4105KHC	sulfurtransferase
CCZ37_15490	ENOG4105D06	uba thif-type nad fad binding protein
CCZ37_15495	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CCZ37_15505	ENOG4105E0X	reductase
CCZ37_15510	ENOG4105CKU	formyltetrahydrofolate synthetase
CCZ37_15520	ENOG4108Z4U	Ferredoxin
CCZ37_15530	ENOG4105DZ0	fad dependent oxidoreductase
CCZ37_15535	ENOG4105PAD	Hydrolase
CCZ37_15540	ENOG4105NXH	GreA GreB family elongation factor
CCZ37_15545	ENOG4108K85	Transcriptional regulator
CCZ37_15560	ENOG4105TMB	Formate nitrite transporter
CCZ37_15565	ENOG4105DUM	transcriptional regulator, lysR family
CCZ37_15570	ENOG4108UQ5	membrane protein YcdZ
CCZ37_15575	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
CCZ37_15580	ENOG4105CGH	5'-nucleotidase
CCZ37_15585	ENOG4105DU1	integral membrane protein, terc
CCZ37_15595	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
CCZ37_15605	ENOG4105KA0	thioesterase Superfamily protein
CCZ37_15620	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CCZ37_15625	ENOG4105CWB	LysR family transcriptional Regulator
CCZ37_15630	ENOG4105CD5	CoA-binding domain protein
CCZ37_15640	ENOG4105CPF	Cell wall formation (By similarity)
CCZ37_15655	ENOG4108ZJT	translation initiation factor, Sui1
CCZ37_15675	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
CCZ37_15685	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CCZ37_15690	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CCZ37_15705	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
CCZ37_15710	ENOG4105VEQ	Cold shock protein
CCZ37_15720	ENOG4105VFU	Rna-binding protein
CCZ37_15735	ENOG410848D	S4 domain protein YaaA
CCZ37_15745	ENOG4105C5H	ABC transporter
CCZ37_15790	ENOG4105KG1	l-proline 3-hydroxylase
CCZ37_15835	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
CCZ37_15840	ENOG41080ET	plasmid maintenance system killer protein
CCZ37_15985	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
CCZ37_16500	ENOG4105D1F	ATP-binding protein
CCZ37_16690	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CCZ37_16815	ENOG4108MIC	Mg-protoporphyrin IX methyl transferase
CCZ37_16885	ENOG4105YB8	TM2 domain containing protein
CCZ37_17160	ENOG4108HYG	acetyltransferase
CCZ37_17200	ENOG4108RXX	maleylacetoacetate isomerase
CCZ37_17235	ENOG4108S58	Phenazine biosynthesis protein PhzF
CCZ37_17245	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
CCZ37_17310	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
CCZ37_17385	ENOG4105QNF	Outer membrane lipoprotein
CCZ37_17455	ENOG4105VXN	addiction module toxin, RelE StbE family
CCZ37_17485	ENOG4108RXX	maleylacetoacetate isomerase
CCZ37_17495	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
CCZ37_17505	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CCZ37_17510	ENOG41082NX	50s ribosomal protein l35
CCZ37_17515	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CCZ37_17520	ENOG4105C22	threonyL-tRNA synthetase
CCZ37_17525	ENOG4105C1J	atp-dependent rna helicase
CCZ37_17560	ENOG4105CEE	C4-dicarboxylate transporter
CCZ37_17565	ENOG4105WH1	Two component transcriptional regulator luxr family
CCZ37_17570	ENOG4105BZU	Histidine kinase
CCZ37_17585	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CCZ37_17595	ENOG4105CUW	cytochrome C-TYPE protein
CCZ37_17605	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
CCZ37_17615	ENOG4105CHU	acetyl-coa acetyltransferase
CCZ37_17625	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CCZ37_17630	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CCZ37_17685	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
CCZ37_17700	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CCZ37_17710	ENOG4105C19	ABC transporter
CCZ37_17715	ENOG4105CKI	cobalamin synthesis protein
CCZ37_17720	ENOG4105CMQ	Chloride channel
CCZ37_17730	ENOG4107KBT	8-Amino-7-oxononanoate synthase
CCZ37_17735	ENOG4108MGY	Histidine kinase
CCZ37_17740	ENOG4105EYH	Exonuclease
CCZ37_17745	ENOG4107RFY	SbcCD D subunit
CCZ37_17750	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
CCZ37_17755	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
CCZ37_17760	ENOG4105DE4	1-phosphofructokinase
CCZ37_17765	ENOG4105DM4	PTS System
CCZ37_17805	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CCZ37_17810	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
CCZ37_17815	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CCZ37_17830	ENOG4105ES1	acyl-CoA reductase
CCZ37_17835	ENOG4108XDE	Acyl transferase is part of the fatty acid reductase system required for aldehyde biosynthesis
CCZ37_17840	ENOG4108M8W	Monooxygenase
CCZ37_17865	ENOG4105CH6	catalase
CCZ37_17875	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CCZ37_17890	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CCZ37_17895	ENOG4108IPW	abc transporter atp-binding protein
CCZ37_17900	ENOG4105CM4	permease protein
CCZ37_17905	ENOG4105DHS	permease protein
CCZ37_17920	ENOG4105KXC	Collagenase
CCZ37_17935	ENOG4107G87	m6 family metalloprotease domain protein
CCZ37_17945	ENOG4107IFA	Lipase (EC 3.1.1.3)
CCZ37_17950	ENOG4106M3D	hemolysin
CCZ37_17955	ENOG4105KUU	lipolytic protein G-D-S-L family
CCZ37_17960	ENOG4105R8A	Heat shock protein
CCZ37_17970	ENOG4105E5M	Multidrug resistance protein D
CCZ37_17975	ENOG4105BZU	Histidine kinase
CCZ37_17985	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CCZ37_17990	ENOG4105C8Q	Methyl-accepting chemotaxis
CCZ37_17995	ENOG41090A4	Pterin carbinolamine dehydratase
CCZ37_18000	ENOG4105MIR	Phenylalanine 4-monooxygenase
CCZ37_18005	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CCZ37_18020	ENOG4105DUM	transcriptional regulator, lysR family
CCZ37_18035	ENOG4108UW5	maltose o-acetyltransferase
CCZ37_18040	ENOG4108UKZ	OsmC family
CCZ37_18045	ENOG4105EE0	oxidoreductase
CCZ37_18050	ENOG4105DHQ	Histidine kinase
CCZ37_18055	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CCZ37_18060	ENOG4108TSE	Transferase
CCZ37_18070	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
CCZ37_18100	ENOG4105C0W	non-ribosomal peptide synthetase
CCZ37_18115	ENOG4107YWA	deoxycytidylate deaminase
CCZ37_18125	ENOG4108IJF	Heavy metal efflux pump, CzcA
CCZ37_18130	ENOG4107KET	secretion protein, HlyD family
CCZ37_18165	ENOG4105BZU	Histidine kinase
CCZ37_18170	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CCZ37_18180	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
CCZ37_18195	ENOG4107RGM	aldo keto reductase
CCZ37_18210	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
CCZ37_18215	ENOG4108M0H	Extracellular lipase
CCZ37_18220	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
CCZ37_18235	ENOG4106MXH	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CCZ37_18245	ENOG4105C1J	atp-dependent rna helicase
CCZ37_18255	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
CCZ37_18260	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
CCZ37_18265	ENOG4108XDN	Transcriptional regulator
CCZ37_18270	ENOG4107SEY	Conserved Protein
CCZ37_18275	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
CCZ37_18290	ENOG4106TD9	Diguanylate cyclase
CCZ37_18295	ENOG4105KK7	inner membrane protein YiaW
CCZ37_18300	ENOG4105EFX	secretion protein, HlyD family
CCZ37_18320	ENOG4105YE1	PilZ domain
CCZ37_18325	ENOG4105D6U	Sodium Glutamate Symporter
CCZ37_18350	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
CCZ37_18365	ENOG4107W52	maltose operon periplasmic protein
CCZ37_18370	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
CCZ37_18405	ENOG4108K4B	hydrolase
CCZ37_18415	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
CCZ37_18430	ENOG4105BZ1	(ABC) transporter
CCZ37_18435	ENOG4108UH6	UPF0754 membrane protein
CCZ37_18440	ENOG4105EYK	Phosphatidylglycerophosphatase B
CCZ37_18460	ENOG4105C8Q	Methyl-accepting chemotaxis
CCZ37_18470	ENOG4105CZV	ABC transporter
CCZ37_18475	ENOG4105FDP	GntR family transcriptional regulator
CCZ37_18485	ENOG4108Q67	UPF0319 protein
CCZ37_18490	ENOG4105C8P	)-transporter
CCZ37_18535	ENOG4105CS6	Rhs element vgr protein
CCZ37_18540	ENOG4108WC9	type VI secretion system effector, hcp1 family
CCZ37_18545	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CCZ37_18550	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
CCZ37_18555	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
CCZ37_18560	ENOG41061ZR	Transcriptional regulator
CCZ37_18565	ENOG4108YYI	Protein of unknown function (DUF2810)
CCZ37_18570	ENOG4105C8Q	Methyl-accepting chemotaxis
CCZ37_18580	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
CCZ37_18590	ENOG4107RGH	Aldehyde dehydrogenase
CCZ37_18595	ENOG4105EW9	transcriptional regulator AsnC family
CCZ37_18600	ENOG4105C8Q	Methyl-accepting chemotaxis
CCZ37_18610	ENOG4105CK7	Sodium proline symporter
CCZ37_18620	ENOG4105C26	Dehydrogenase
CCZ37_18635	ENOG4105E6M	Sulphatase-modifying factor protein
CCZ37_18640	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
CCZ37_18645	ENOG4107QZV	Type I secretion membrane fusion protein
CCZ37_18660	ENOG4108JJA	ABC, transporter
CCZ37_18670	ENOG4105BZU	Histidine kinase
CCZ37_18680	ENOG4105C8Q	Methyl-accepting chemotaxis
CCZ37_18685	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CCZ37_18695	ENOG4105BZU	Histidine kinase
CCZ37_18700	ENOG4105C8Q	Methyl-accepting chemotaxis
CCZ37_18705	ENOG4108V3W	Chemotaxis protein, CheW
CCZ37_18710	ENOG4108V3W	Chemotaxis protein, CheW
CCZ37_18715	ENOG4105CBS	Chea signal transduction histidine kinase
CCZ37_18720	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CCZ37_18730	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)