locus-tag	class	description
CCZ37_00015	COG0592	DNA-directed DNA polymerase activity
CCZ37_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CCZ37_00025	COG0187	DNA topoisomerase II activity
CCZ37_00035	COG3977	Valine--pyruvate aminotransferase
CCZ37_00045	COG0752	glycyl-tRNA synthetase alpha subunit
CCZ37_00050	COG2119	membrane
CCZ37_00075	COG0604	alcohol dehydrogenase
CCZ37_00085	COG0129	dihydroxy-acid dehydratase activity
CCZ37_00090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CCZ37_00095	COG3978	acetolactate synthase activity
CCZ37_00105	COG0606	chelatase, subunit chli
CCZ37_00115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CCZ37_00120	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CCZ37_00135	COG3084	Protein conserved in bacteria
CCZ37_00145	COG1272	protein, Hemolysin III
CCZ37_00150	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CCZ37_00155	COG0569	domain protein
CCZ37_00160	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CCZ37_00160	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CCZ37_00165	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CCZ37_00170	COG0242	peptide deformylase activity
CCZ37_00175	COG1652	LysM domain
CCZ37_00180	COG0758	DNA mediated transformation
CCZ37_00185	COG2922	Belongs to the Smg family
CCZ37_00190	COG0551	DNA topoisomerase type I activity
CCZ37_00195	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CCZ37_00200	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CCZ37_00205	COG0009	L-threonylcarbamoyladenylate synthase
CCZ37_00210	COG0408	coproporphyrinogen oxidase activity
CCZ37_00215	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CCZ37_00225	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CCZ37_00300	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CCZ37_00305	COG5001	Diguanylate cyclase
CCZ37_00305	COG3300	MHYT domain
CCZ37_00315	COG3852	Histidine kinase
CCZ37_00325	COG0174	glutamine synthetase
CCZ37_00340	COG1490	D-aminoacyl-tRNA deacylase activity
CCZ37_00345	COG0456	acetyltransferase
CCZ37_00355	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CCZ37_00360	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CCZ37_00365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CCZ37_00370	COG3031	protein transport across the cell outer membrane
CCZ37_00380	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CCZ37_00385	COG1459	type II secretion system
CCZ37_00390	COG2165	general secretion pathway protein
CCZ37_00395	COG2165	general secretion pathway protein
CCZ37_00400	COG2165	general secretion pathway protein
CCZ37_00405	COG4795	General secretion pathway protein
CCZ37_00410	COG3156	type II secretion system protein K
CCZ37_00415	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CCZ37_00420	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CCZ37_00430	COG1218	3'(2'),5'-bisphosphate nucleotidase
CCZ37_00435	COG0494	nUDIX hydrolase
CCZ37_00440	COG0316	Belongs to the HesB IscA family
CCZ37_00440	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CCZ37_00445	COG1040	competence protein
CCZ37_00450	COG0596	Alpha beta hydrolase
CCZ37_00460	COG2183	response to ionizing radiation
CCZ37_00465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CCZ37_00480	COG0745	RESPONSE REGULATOR receiver
CCZ37_00490	COG2233	PERMEase
CCZ37_00495	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CCZ37_00500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CCZ37_00505	COG1758	RNA polymerase activity
CCZ37_00510	COG0194	GDP metabolic process
CCZ37_00515	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CCZ37_00520	COG0248	Ppx GppA phosphatase
CCZ37_00530	COG3118	belongs to the thioredoxin family
CCZ37_00535	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CCZ37_00545	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CCZ37_00600	COG3071	HemY protein
CCZ37_00605	COG2959	enzyme of heme biosynthesis
CCZ37_00610	COG1587	Uroporphyrinogen-III synthase
CCZ37_00620	COG3072	Adenylate cyclase
CCZ37_00635	COG0019	diaminopimelate decarboxylase activity
CCZ37_00650	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CCZ37_00655	COG1011	Hydrolase
CCZ37_00670	COG0561	phosphatase activity
CCZ37_00675	COG2267	carboxylic ester hydrolase activity
CCZ37_00680	COG1280	lysine exporter protein (LysE YggA)
CCZ37_00685	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CCZ37_00690	COG0783	Belongs to the Dps family
CCZ37_00725	COG2095	MarC family integral membrane protein
CCZ37_00735	COG0742	ribosomal rna small subunit methyltransferase
CCZ37_00740	COG0552	protein localization to endoplasmic reticulum
CCZ37_00745	COG2884	Cell division ATP-binding protein ftsE
CCZ37_00750	COG2177	Part of the ABC transporter FtsEX involved in
CCZ37_00755	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CCZ37_00765	COG0705	Rhomboid family
CCZ37_00770	COG1580	Controls the rotational direction of flagella during chemotaxis
CCZ37_00775	COG3161	chorismate lyase activity
CCZ37_00785	COG2937	Belongs to the GPAT DAPAT family
CCZ37_00800	COG0534	Mate efflux family protein
CCZ37_00845	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CCZ37_00855	COG1461	Dihydroxyacetone kinase
CCZ37_00860	COG2376	Dihydroxyacetone kinase
CCZ37_00875	COG2223	nitrite transmembrane transporter activity
CCZ37_00915	COG4206	TonB-dependent receptor
CCZ37_00920	COG1404	Belongs to the peptidase S8 family
CCZ37_00925	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CCZ37_00965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CCZ37_00975	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CCZ37_00980	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CCZ37_00980	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CCZ37_00985	COG1072	(Pantothenic acid kinase))
CCZ37_01010	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CCZ37_01015	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CCZ37_01020	COG0250	Participates in transcription elongation, termination and antitermination
CCZ37_01030	COG0081	regulation of translation
CCZ37_01035	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CCZ37_01040	COG0222	ribosome binding
CCZ37_01045	COG0085	RNA polymerase activity
CCZ37_01050	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CCZ37_01055	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CCZ37_01060	COG2816	NAD+ diphosphatase activity
CCZ37_01080	COG4942	peptidase
CCZ37_01085	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CCZ37_01095	COG0490	domain, Protein
CCZ37_01095	COG0471	metal ion transport
CCZ37_01105	COG1162	GTPase activity
CCZ37_01110	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CCZ37_01155	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CCZ37_01160	COG0802	atpase or kinase
CCZ37_01165	COG0860	N-Acetylmuramoyl-L-alanine amidase
CCZ37_01170	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CCZ37_01175	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CCZ37_01180	COG1923	regulation of RNA biosynthetic process
CCZ37_01185	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CCZ37_01190	COG0330	HflC and HflK could
CCZ37_01195	COG0330	HflC and HflK could
CCZ37_01200	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CCZ37_01215	COG0545	Peptidyl-prolyl cis-trans isomerase
CCZ37_01220	COG2964	Protein conserved in bacteria
CCZ37_01225	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CCZ37_01230	COG2923	Belongs to the DsrF TusC family
CCZ37_01245	COG0049	tRNA binding
CCZ37_01250	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CCZ37_01255	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CCZ37_01260	COG0360	Binds together with S18 to 16S ribosomal RNA
CCZ37_01265	COG2965	DNA replication, synthesis of RNA primer
CCZ37_01275	COG0359	binds to the 23S rRNA
CCZ37_01285	COG0305	Participates in initiation and elongation during chromosome replication
CCZ37_01290	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CCZ37_01295	COG0166	Belongs to the GPI family
CCZ37_01305	COG0735	belongs to the Fur family
CCZ37_01310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CCZ37_01330	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CCZ37_01340	COG0175	sulfate reduction
CCZ37_01425	COG1410	methionine synthase
CCZ37_01425	COG0646	methionine synthase
CCZ37_01430	COG0527	aspartate kinase activity
CCZ37_01435	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CCZ37_01450	COG2239	Acts as a magnesium transporter
CCZ37_01460	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CCZ37_01475	COG0629	single-stranded DNA binding
CCZ37_01480	COG2199	diguanylate cyclase activity
CCZ37_01480	COG2200	EAL domain
CCZ37_01505	COG3267	Type II secretory pathway component ExeA
CCZ37_01505	COG3409	Peptidoglycan-binding domain 1 protein
CCZ37_01515	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CCZ37_01520	COG1459	type II secretion system
CCZ37_01565	COG1077	Cell shape determining protein MreB Mrl
CCZ37_01570	COG1792	Involved in formation and maintenance of cell shape
CCZ37_01575	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CCZ37_01580	COG0424	maF-like protein
CCZ37_01585	COG1530	ribonuclease E activity
CCZ37_01590	COG3164	Protein of unknown function
CCZ37_01595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CCZ37_01600	COG0312	modulator of DNA gyrase
CCZ37_01605	COG2235	arginine
CCZ37_01625	COG0589	response to stress
CCZ37_01655	COG0531	amino acid
CCZ37_01660	COG0142	geranyltranstransferase activity
CCZ37_01675	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CCZ37_01680	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CCZ37_01685	COG2966	Psort location CytoplasmicMembrane, score
CCZ37_01690	COG3610	response to peptide
CCZ37_01700	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CCZ37_01705	COG2967	ApaG domain
CCZ37_01715	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CCZ37_01720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CCZ37_01725	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CCZ37_01730	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CCZ37_01780	COG0741	lytic transglycosylase activity
CCZ37_01795	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CCZ37_01800	COG2066	Belongs to the glutaminase family
CCZ37_01805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CCZ37_01820	COG1872	DUF167
CCZ37_01825	COG0762	integral membrane protein
CCZ37_01830	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CCZ37_01835	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CCZ37_01855	COG1678	Uncharacterized ACR, COG1678
CCZ37_01865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CCZ37_01870	COG2356	endonuclease I
CCZ37_01875	COG3091	SprT-like family
CCZ37_01880	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CCZ37_01885	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CCZ37_01915	COG2433	Pfam Transposase IS66
CCZ37_01930	COG2184	nucleotidyltransferase activity
CCZ37_01940	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CCZ37_01945	COG0126	phosphoglycerate kinase activity
CCZ37_01955	COG0191	fructose-bisphosphate aldolase activity
CCZ37_01960	COG0668	transmembrane transport
CCZ37_01980	COG3706	GGDEF domain
CCZ37_01990	COG0469	pyruvate kinase activity
CCZ37_01995	COG1349	DNA-binding transcription factor activity
CCZ37_02035	COG3501	Rhs element vgr protein
CCZ37_02085	COG2433	Pfam Transposase IS66
CCZ37_02105	COG3550	peptidyl-serine autophosphorylation
CCZ37_02120	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CCZ37_02125	COG0358	DNA primase activity
CCZ37_02130	COG1610	YqeY-like protein
CCZ37_02155	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CCZ37_02160	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CCZ37_02165	COG1968	undecaprenyl-diphosphatase activity
CCZ37_02170	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CCZ37_02175	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CCZ37_02180	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CCZ37_02185	COG0585	pseudouridine synthase activity
CCZ37_02190	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CCZ37_02195	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CCZ37_02200	COG4942	peptidase
CCZ37_02200	COG1388	LysM domain
CCZ37_02205	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CCZ37_02210	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CCZ37_02230	COG4208	sulfate ABC transporter
CCZ37_02235	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CCZ37_02240	COG1546	Belongs to the CinA family
CCZ37_02245	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CCZ37_02250	COG2137	regulation of response to DNA damage stimulus
CCZ37_02255	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CCZ37_02260	COG0527	aspartate kinase activity
CCZ37_02310	COG3630	sodium ion export across plasma membrane
CCZ37_02315	COG0511	ligase activity, forming carbon-carbon bonds
CCZ37_02315	COG5016	pyruvate
CCZ37_02320	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CCZ37_02325	COG1063	alcohol dehydrogenase
CCZ37_02330	COG1238	metal cluster binding
CCZ37_02335	COG0612	Peptidase, M16
CCZ37_02350	COG4536	flavin adenine dinucleotide binding
CCZ37_02355	COG4137	Cytochrome C assembly protein
CCZ37_02360	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CCZ37_02380	COG0335	large ribosomal subunit rRNA binding
CCZ37_02385	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CCZ37_02390	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CCZ37_02395	COG0237	dephospho-CoA kinase activity
CCZ37_02405	COG1459	type II secretion system
CCZ37_02410	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CCZ37_02420	COG0157	Belongs to the NadC ModD family
CCZ37_02430	COG0716	FMN binding
CCZ37_02435	COG4974	Belongs to the 'phage' integrase family
CCZ37_02440	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CCZ37_02445	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CCZ37_02450	COG2186	Transcriptional regulator
CCZ37_02455	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CCZ37_02460	COG0508	dehydrogenase complex catalyzes the overall conversion of
CCZ37_02465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CCZ37_02480	COG0288	reversible hydration of carbon dioxide
CCZ37_02485	COG0659	secondary active sulfate transmembrane transporter activity
CCZ37_02490	COG1131	(ABC) transporter
CCZ37_02495	COG0842	Transport permease protein
CCZ37_02515	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CCZ37_02525	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CCZ37_02530	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CCZ37_02535	COG1489	DNA binding
CCZ37_02540	COG1643	Atp-dependent helicase
CCZ37_02545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CCZ37_02550	COG1752	Esterase of the alpha-beta hydrolase superfamily
CCZ37_02555	COG1049	propionate catabolic process, 2-methylcitrate cycle
CCZ37_02590	COG1121	(ABC) transporter
CCZ37_02595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CCZ37_02605	COG0745	RESPONSE REGULATOR receiver
CCZ37_02615	COG4771	TonB-dependent receptor
CCZ37_02620	COG1929	Belongs to the glycerate kinase type-1 family
CCZ37_02635	COG0004	ammonium transporteR
CCZ37_02640	COG1840	ABC-type Fe3 transport system, periplasmic component
CCZ37_02650	COG3842	ATPase activity
CCZ37_02655	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CCZ37_02670	COG2971	BadF BadG BcrA BcrD
CCZ37_02680	COG4608	Belongs to the ABC transporter superfamily
CCZ37_02685	COG0444	Belongs to the ABC transporter superfamily
CCZ37_02690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCZ37_02715	COG0628	permease
CCZ37_02720	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CCZ37_02725	COG0316	Belongs to the HesB IscA family
CCZ37_02740	COG0739	heme binding
CCZ37_02745	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CCZ37_02755	COG2027	D-alanyl-D-alanine carboxypeptidase
CCZ37_02760	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CCZ37_02765	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CCZ37_02770	COG1534	Rna-binding protein
CCZ37_02780	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CCZ37_02785	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CCZ37_02790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CCZ37_02795	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CCZ37_02810	COG0779	Required for maturation of 30S ribosomal subunits
CCZ37_02815	COG0195	Participates in both transcription termination and antitermination
CCZ37_02820	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CCZ37_02825	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CCZ37_02830	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CCZ37_02850	COG1846	Transcriptional regulator
CCZ37_02880	COG3153	acetyltransferase
CCZ37_02905	COG0513	Belongs to the DEAD box helicase family
CCZ37_02910	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CCZ37_02925	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CCZ37_02930	COG2204	response regulator
CCZ37_02940	COG0667	Aldo Keto reductase
CCZ37_02945	COG3066	DNA modification
CCZ37_02950	COG0494	nUDIX hydrolase
CCZ37_02960	COG0730	response to heat
CCZ37_02970	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CCZ37_02975	COG1283	sodium-dependent phosphate transmembrane transporter activity
CCZ37_02980	COG0583	DNA-binding transcription factor activity
CCZ37_02985	COG0640	Transcriptional regulator
CCZ37_02995	COG0728	peptidoglycan biosynthetic process
CCZ37_03000	COG0196	riboflavin kinase activity
CCZ37_03010	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CCZ37_03015	COG1047	Peptidyl-prolyl cis-trans
CCZ37_03025	COG1966	Carbon starvation protein
CCZ37_03035	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CCZ37_03040	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CCZ37_03045	COG1472	Belongs to the glycosyl hydrolase 3 family
CCZ37_03050	COG3279	Response regulator of the LytR AlgR family
CCZ37_03055	COG3275	phosphorelay sensor kinase activity
CCZ37_03060	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CCZ37_03065	COG0287	Prephenate dehydrogenase
CCZ37_03065	COG1605	Chorismate mutase
CCZ37_03075	COG0488	(ABC) transporter
CCZ37_03090	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CCZ37_03095	COG5001	Diguanylate cyclase
CCZ37_03100	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CCZ37_03105	COG0077	Prephenate dehydratase
CCZ37_03105	COG1605	Chorismate mutase
CCZ37_03110	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CCZ37_03115	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CCZ37_03120	COG0564	pseudouridine synthase activity
CCZ37_03130	COG0542	response to heat
CCZ37_03170	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CCZ37_03185	COG0745	RESPONSE REGULATOR receiver
CCZ37_03190	COG5002	protein histidine kinase activity
CCZ37_03200	COG0248	Ppx GppA phosphatase
CCZ37_03205	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CCZ37_03215	COG0581	inorganic phosphate transmembrane transporter activity
CCZ37_03220	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CCZ37_03225	COG0704	Plays a role in the regulation of phosphate uptake
CCZ37_03230	COG3142	Participates in the control of copper homeostasis
CCZ37_03235	COG0450	alkyl hydroperoxide reductase
CCZ37_03240	COG0583	DNA-binding transcription factor activity
CCZ37_03245	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CCZ37_03255	COG0517	IMP dehydrogenase activity
CCZ37_03260	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CCZ37_03270	COG1862	Preprotein translocase
CCZ37_03275	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CCZ37_03280	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CCZ37_03285	COG0483	inositol monophosphate 1-phosphatase activity
CCZ37_03290	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CCZ37_03295	COG1959	2 iron, 2 sulfur cluster binding
CCZ37_03305	COG0822	iron-sulfur transferase activity
CCZ37_03310	COG0316	Belongs to the HesB IscA family
CCZ37_03315	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CCZ37_03320	COG0443	Heat shock 70 kDa protein
CCZ37_03325	COG0633	Ferredoxin
CCZ37_03330	COG2975	iron-sulfur cluster assembly
CCZ37_03335	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CCZ37_03355	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CCZ37_03360	COG0124	histidyl-tRNA synthetase
CCZ37_03365	COG2976	Protein conserved in bacteria
CCZ37_03370	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CCZ37_03375	COG1160	GTP binding
CCZ37_03390	COG0517	IMP dehydrogenase activity
CCZ37_03390	COG0516	GMP reductase activity
CCZ37_03395	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CCZ37_03395	COG0519	Catalyzes the synthesis of GMP from XMP
CCZ37_03400	COG0351	phosphomethylpyrimidine kinase
CCZ37_03410	COG1584	GPR1 FUN34 yaaH family protein
CCZ37_03415	COG1115	amino acid carrier protein
CCZ37_03420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCZ37_03440	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CCZ37_03445	COG3711	transcriptional antiterminator
CCZ37_03445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCZ37_03460	COG3964	amidohydrolase
CCZ37_03490	COG0556	nucleotide-excision repair
CCZ37_03515	COG1686	Belongs to the peptidase S11 family
CCZ37_03545	COG2867	negative regulation of translational initiation
CCZ37_03550	COG2914	Belongs to the UPF0125 (RnfH) family
CCZ37_03555	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CCZ37_03560	COG0497	DNA recombination
CCZ37_03570	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CCZ37_03575	COG0443	Heat shock 70 kDa protein
CCZ37_03580	COG0484	heat shock protein binding
CCZ37_03610	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CCZ37_03620	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CCZ37_03645	COG0442	prolyl-tRNA aminoacylation
CCZ37_03650	COG1720	tRNA m6t6A37 methyltransferase activity
CCZ37_03660	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CCZ37_03690	COG3098	single-species biofilm formation
CCZ37_03695	COG0564	pseudouridine synthase activity
CCZ37_03700	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CCZ37_03705	COG0142	geranyltranstransferase activity
CCZ37_03715	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CCZ37_03725	COG0301	tRNA thio-modification
CCZ37_03725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CCZ37_03730	COG0583	DNA-binding transcription factor activity
CCZ37_03735	COG2363	Small membrane protein
CCZ37_03745	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CCZ37_03750	COG1611	Belongs to the LOG family
CCZ37_03755	COG3706	GGDEF domain
CCZ37_03775	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
CCZ37_03780	COG1464	Belongs to the NlpA lipoprotein family
CCZ37_03785	COG2011	ABC-type metal ion transport system permease component
CCZ37_03795	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CCZ37_03810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CCZ37_03810	COG1263	PTS System
CCZ37_03815	COG0366	Alpha amylase catalytic
CCZ37_03845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCZ37_03850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCZ37_03855	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CCZ37_03860	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CCZ37_03865	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CCZ37_03870	COG1045	serine acetyltransferase
CCZ37_03890	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CCZ37_03910	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CCZ37_03950	COG0489	protein tyrosine kinase activity
CCZ37_03955	COG1596	polysaccharide export
CCZ37_03970	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CCZ37_03985	COG0321	lipoyl(octanoyl) transferase activity
CCZ37_03990	COG2921	Belongs to the UPF0250 family
CCZ37_03995	COG1686	Belongs to the peptidase S11 family
CCZ37_04000	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CCZ37_04005	COG0772	Belongs to the SEDS family
CCZ37_04010	COG0768	penicillin binding
CCZ37_04015	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CCZ37_04020	COG0799	negative regulation of ribosome biogenesis
CCZ37_04025	COG1466	dna polymerase III delta subunit
CCZ37_04030	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
CCZ37_04035	COG0495	leucyl-tRNA aminoacylation
CCZ37_04040	COG2888	peptidyl-tyrosine sulfation
CCZ37_04045	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CCZ37_04050	COG4535	Mg2 and Co2 transporter CorC
CCZ37_04055	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CCZ37_04060	COG1702	phosphate starvation-inducible protein PhoH
CCZ37_04065	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CCZ37_04070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCZ37_04075	COG2190	(PTS) system
CCZ37_04080	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CCZ37_04085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCZ37_04090	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CCZ37_04095	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CCZ37_04100	COG3115	cell septum assembly
CCZ37_04120	COG0789	Transcriptional regulator
CCZ37_04130	COG0330	HflC and HflK could
CCZ37_04135	COG3118	belongs to the thioredoxin family
CCZ37_04140	COG1090	epimerase
CCZ37_04145	COG0622	Phosphoesterase
CCZ37_04160	COG3710	Transcriptional regulator
CCZ37_04165	COG0326	Molecular chaperone. Has ATPase activity
CCZ37_04175	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CCZ37_04180	COG3104	oligopeptide transport
CCZ37_04190	COG0367	asparagine synthase
CCZ37_04195	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CCZ37_04195	COG4651	solute:proton antiporter activity
CCZ37_04200	COG1846	Transcriptional regulator
CCZ37_04200	COG1940	carbohydrate kinase activity
CCZ37_04205	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CCZ37_04210	COG2190	(PTS) system
CCZ37_04210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CCZ37_04210	COG1263	PTS System
CCZ37_04215	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CCZ37_04235	COG0285	dihydrofolate synthase activity
CCZ37_04240	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CCZ37_04245	COG1286	toxin biosynthetic process
CCZ37_04250	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CCZ37_04255	COG2056	Na+-H+ antiporter family
CCZ37_04260	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CCZ37_04270	COG0346	lactoylglutathione lyase activity
CCZ37_04275	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CCZ37_04295	COG4656	Part of a membrane complex involved in electron transport
CCZ37_04300	COG2878	Part of a membrane complex involved in electron transport
CCZ37_04305	COG4657	Part of a membrane complex involved in electron transport
CCZ37_04315	COG4774	siderophore transport
CCZ37_04315	COG1629	transport
CCZ37_04320	COG2382	esterase
CCZ37_04340	COG3433	isochorismatase activity
CCZ37_04340	COG1535	isochorismatase
CCZ37_04345	COG1021	2,3-dihydroxybenzoate-AMP ligase
CCZ37_04350	COG1169	isochorismate synthase
CCZ37_04355	COG1028	Short-chain dehydrogenase reductase Sdr
CCZ37_04360	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CCZ37_04370	COG4771	TonB-dependent receptor
CCZ37_04425	COG2194	sulfuric ester hydrolase activity
CCZ37_04430	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CCZ37_04435	COG1368	sulfuric ester hydrolase activity
CCZ37_04455	COG5001	Diguanylate cyclase
CCZ37_04455	COG4251	negative regulation of phosphorylation
CCZ37_04455	COG2203	Gaf domain
CCZ37_04455	COG3706	GGDEF domain
CCZ37_04460	COG0784	Response regulator, receiver
CCZ37_04460	COG2205	protein histidine kinase activity
CCZ37_04460	COG5002	protein histidine kinase activity
CCZ37_04475	COG3850	Histidine kinase
CCZ37_04475	COG5002	protein histidine kinase activity
CCZ37_04495	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CCZ37_04510	COG0800	Aldolase
CCZ37_04535	COG0784	Response regulator, receiver
CCZ37_04535	COG5002	protein histidine kinase activity
CCZ37_04550	COG0601	transmembrane transport
CCZ37_04555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCZ37_04560	COG0444	Belongs to the ABC transporter superfamily
CCZ37_04570	COG0435	Glutathione S-transferase
CCZ37_04575	COG0280	phosphate acetyltransferase
CCZ37_04575	COG0857	belongs to the CobB CobQ family
CCZ37_04580	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CCZ37_04585	COG3092	negative regulation of chromosome organization
CCZ37_04595	COG4120	Belongs to the binding-protein-dependent transport system permease family
CCZ37_04605	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CCZ37_04610	COG0653	protein targeting
CCZ37_04620	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CCZ37_04625	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CCZ37_04635	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CCZ37_04650	COG2226	methyltransferase
CCZ37_04655	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CCZ37_04665	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CCZ37_04670	COG2186	Transcriptional regulator
CCZ37_04685	COG0537	adenosine 5'-monophosphoramidase activity
CCZ37_04715	COG1252	NADH dehydrogenase
CCZ37_04730	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CCZ37_04740	COG4591	ABC-type transport system involved in lipoprotein release permease component
CCZ37_04745	COG1136	(ABC) transporter
CCZ37_04750	COG4591	ABC-type transport system involved in lipoprotein release permease component
CCZ37_04760	COG0658	competence protein
CCZ37_04760	COG2333	competence protein COMEC
CCZ37_04765	COG1132	(ABC) transporter
CCZ37_04780	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CCZ37_04785	COG2719	SpoVR family
CCZ37_04790	COG2718	Belongs to the UPF0229 family
CCZ37_04795	COG2766	serine protein kinase
CCZ37_04805	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CCZ37_04820	COG1882	Formate acetyltransferase
CCZ37_04845	COG4215	(ABC) transporter
CCZ37_04850	COG4160	amino acid transport
CCZ37_04855	COG0708	Exodeoxyribonuclease III
CCZ37_04910	COG3923	Primosomal replication protein n
CCZ37_04920	COG1199	ATP-dependent helicase activity
CCZ37_04925	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CCZ37_04930	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CCZ37_04935	COG3012	SEC-C Motif Domain Protein
CCZ37_04940	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CCZ37_04945	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CCZ37_04950	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CCZ37_04955	COG0215	cysteine-tRNA ligase activity
CCZ37_04960	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CCZ37_04965	COG0632	four-way junction helicase activity
CCZ37_04970	COG2255	four-way junction helicase activity
CCZ37_04975	COG1271	oxidase subunit
CCZ37_04980	COG1294	oxidase, subunit
CCZ37_04985	COG4890	Cyd operon protein YbgT
CCZ37_04990	COG3790	cyd operon protein YbgE
CCZ37_04995	COG0824	Thioesterase
CCZ37_05000	COG0811	peptide transport
CCZ37_05020	COG2885	chlorophyll binding
CCZ37_05025	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CCZ37_05040	COG5002	protein histidine kinase activity
CCZ37_05040	COG0784	Response regulator, receiver
CCZ37_05065	COG0747	negative chemotaxis
CCZ37_05075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCZ37_05080	COG0444	Belongs to the ABC transporter superfamily
CCZ37_05085	COG4608	Belongs to the ABC transporter superfamily
CCZ37_05095	COG1609	Transcriptional regulator
CCZ37_05105	COG4580	involved in the transport of maltose and maltodextrins
CCZ37_05120	COG1472	Belongs to the glycosyl hydrolase 3 family
CCZ37_05130	COG1012	belongs to the aldehyde dehydrogenase family
CCZ37_05150	COG1960	acyl-CoA dehydrogenase activity
CCZ37_05155	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CCZ37_05185	COG0277	FAD linked oxidase domain protein
CCZ37_05185	COG0247	lactate metabolic process
CCZ37_05200	COG2986	histidine ammonia-lyase
CCZ37_05210	COG0010	Belongs to the arginase family
CCZ37_05215	COG1228	amidohydrolase
CCZ37_05220	COG2188	Transcriptional regulator
CCZ37_05230	COG3099	Belongs to the UPF0263 family
CCZ37_05235	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CCZ37_05245	COG0417	DNA replication proofreading
CCZ37_05250	COG2197	response regulator
CCZ37_05255	COG0322	excinuclease ABC activity
CCZ37_05295	COG0072	phenylalanine-tRNA ligase activity
CCZ37_05295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCZ37_05310	COG0500	methyltransferase
CCZ37_05320	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CCZ37_05325	COG0295	cytidine deaminase activity
CCZ37_05330	COG1346	cytolysis
CCZ37_05340	COG2925	Exonuclease
CCZ37_05370	COG2994	toxin metabolic process
CCZ37_05375	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CCZ37_05375	COG3064	Membrane
CCZ37_05375	COG1073	alpha beta
CCZ37_05385	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CCZ37_05400	COG2988	succinylglutamate desuccinylase activity
CCZ37_05405	COG4139	cobalamin transport
CCZ37_05430	COG0583	DNA-binding transcription factor activity
CCZ37_05440	COG1451	nucleotide metabolic process
CCZ37_05455	COG3063	Type IV pilus biogenesis stability protein PilW
CCZ37_05480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCZ37_05495	COG3290	protein histidine kinase activity
CCZ37_05500	COG4565	transcriptional regulatory protein
CCZ37_05510	COG0835	chemotaxis
CCZ37_05510	COG0784	Response regulator, receiver
CCZ37_05530	COG3706	GGDEF domain
CCZ37_05530	COG0745	RESPONSE REGULATOR receiver
CCZ37_05545	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CCZ37_05575	COG2116	formate transmembrane transporter activity
CCZ37_05580	COG4459	periplasmic nitrate reductase
CCZ37_05585	COG3005	denitrification pathway
CCZ37_05590	COG0243	molybdopterin cofactor binding
CCZ37_05610	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CCZ37_05615	COG1215	transferase activity, transferring glycosyl groups
CCZ37_05620	COG0438	transferase activity, transferring glycosyl groups
CCZ37_05655	COG0438	transferase activity, transferring glycosyl groups
CCZ37_05665	COG2204	response regulator
CCZ37_05710	COG1227	inorganic diphosphatase activity
CCZ37_05730	COG4172	Belongs to the ABC transporter superfamily
CCZ37_05740	COG4171	peptide transport system, permease
CCZ37_05745	COG4168	peptide transport system, permease
CCZ37_05755	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CCZ37_05760	COG1842	Phage shock protein A
CCZ37_05775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCZ37_05780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCZ37_05790	COG0519	Catalyzes the synthesis of GMP from XMP
CCZ37_05795	COG0626	cystathionine gamma-synthase activity
CCZ37_05805	COG0733	neurotransmitter:sodium symporter activity
CCZ37_05810	COG0564	pseudouridine synthase activity
CCZ37_05820	COG2200	EAL domain
CCZ37_05825	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CCZ37_05830	COG4136	ATPase activity
CCZ37_05835	COG4135	transport system, permease component
CCZ37_05840	COG4134	Bacterial extracellular solute-binding protein
CCZ37_05850	COG3313	Fe-S protein
CCZ37_05865	COG0513	Belongs to the DEAD box helicase family
CCZ37_05880	COG2205	protein histidine kinase activity
CCZ37_05895	COG1061	Type III restriction enzyme res subunit
CCZ37_05900	COG1187	pseudouridine synthase activity
CCZ37_05905	COG2814	Major facilitator Superfamily
CCZ37_05915	COG0702	epimerase
CCZ37_05920	COG0534	Mate efflux family protein
CCZ37_05925	COG4181	ATPase activity
CCZ37_05940	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CCZ37_05960	COG0019	diaminopimelate decarboxylase activity
CCZ37_05990	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CCZ37_05995	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CCZ37_06000	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CCZ37_06010	COG0840	transmembrane signaling receptor activity
CCZ37_06025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CCZ37_06025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCZ37_06025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CCZ37_06030	COG2207	Transcriptional regulator
CCZ37_06040	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CCZ37_06050	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CCZ37_06055	COG5002	protein histidine kinase activity
CCZ37_06060	COG0745	RESPONSE REGULATOR receiver
CCZ37_06090	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CCZ37_06095	COG0372	Belongs to the citrate synthase family
CCZ37_06100	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CCZ37_06105	COG2828	Protein conserved in bacteria
CCZ37_06120	COG0561	phosphatase activity
CCZ37_06125	COG0602	queuosine metabolic process
CCZ37_06195	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CCZ37_06200	COG1254	Belongs to the acylphosphatase family
CCZ37_06205	COG2920	part of a sulfur-relay system
CCZ37_06210	COG0670	Belongs to the BI1 family
CCZ37_06215	COG1126	abc transporter atp-binding protein
CCZ37_06220	COG0765	amino acid transport
CCZ37_06225	COG4597	amino acid ABC transporter
CCZ37_06230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCZ37_06235	COG1648	precorrin-2 dehydrogenase activity
CCZ37_06235	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CCZ37_06245	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CCZ37_06250	COG0574	Belongs to the PEP-utilizing enzyme family
CCZ37_06250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CCZ37_06275	COG3008	intermembrane lipid transfer
CCZ37_06280	COG2995	paraquat-inducible protein a
CCZ37_06285	COG1132	(ABC) transporter
CCZ37_06290	COG1956	GAF domain-containing protein
CCZ37_06310	COG0308	aminopeptidase N
CCZ37_06320	COG2902	Dehydrogenase
CCZ37_06325	COG0167	dihydroorotate dehydrogenase activity
CCZ37_06335	COG0116	Belongs to the methyltransferase superfamily
CCZ37_06335	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CCZ37_06360	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CCZ37_06365	COG1067	ATP-dependent peptidase activity
CCZ37_06370	COG3120	sequence-specific DNA binding
CCZ37_06390	COG3278	Belongs to the heme-copper respiratory oxidase family
CCZ37_06405	COG2010	Cytochrome c
CCZ37_06415	COG2217	Heavy metal translocating P-type atpase
CCZ37_06430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CCZ37_06435	COG0589	response to stress
CCZ37_06460	COG3842	ATPase activity
CCZ37_06465	COG1176	ABC-type spermidine putrescine transport system, permease component I
CCZ37_06470	COG1177	transmembrane transport
CCZ37_06475	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CCZ37_06480	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CCZ37_06485	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CCZ37_06490	COG0488	(ABC) transporter
CCZ37_06495	COG0746	molybdenum cofactor guanylyltransferase activity
CCZ37_06500	COG1763	Mo-molybdopterin cofactor biosynthetic process
CCZ37_06525	COG0791	NLP P60 protein
CCZ37_06550	COG1793	dna ligase
CCZ37_06555	COG4667	esterase of the alpha-beta hydrolase superfamily
CCZ37_06570	COG0848	biopolymer transport protein
CCZ37_06575	COG0811	peptide transport
CCZ37_06580	COG0811	peptide transport
CCZ37_06605	COG0625	glutathione transferase activity
CCZ37_06615	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CCZ37_06635	COG1115	amino acid carrier protein
CCZ37_06640	COG1280	lysine exporter protein (LysE YggA)
CCZ37_06645	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CCZ37_06650	COG0477	Major facilitator Superfamily
CCZ37_06665	COG1643	Atp-dependent helicase
CCZ37_06685	COG3706	GGDEF domain
CCZ37_06725	COG1609	Transcriptional regulator
CCZ37_06730	COG2723	6-phospho-beta-galactosidase activity
CCZ37_06735	COG0513	Belongs to the DEAD box helicase family
CCZ37_06740	COG0243	molybdopterin cofactor binding
CCZ37_06745	COG3005	denitrification pathway
CCZ37_06750	COG1278	Cold shock
CCZ37_06765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCZ37_06765	COG4191	Histidine kinase
CCZ37_06770	COG0471	metal ion transport
CCZ37_06780	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CCZ37_06795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CCZ37_06800	COG3283	Transcriptional regulator of aromatic amino acids metabolism
CCZ37_06805	COG3768	UPF0283 membrane protein
CCZ37_06810	COG3106	COG3106 Predicted ATPase
CCZ37_06835	COG0814	amino acid
CCZ37_06840	COG1760	l-serine dehydratase
CCZ37_06845	COG0589	response to stress
CCZ37_06850	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CCZ37_06850	COG2111	Na H antiporter
CCZ37_06870	COG2212	antiporter activity
CCZ37_06875	COG1320	monovalent cation:proton antiporter activity
CCZ37_06885	COG2356	endonuclease I
CCZ37_06890	COG0720	synthase
CCZ37_06900	COG0017	Asparaginyl-tRNA synthetase
CCZ37_06910	COG2201	protein-glutamate methylesterase activity
CCZ37_06915	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CCZ37_06920	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CCZ37_06925	COG0835	chemotaxis
CCZ37_06935	COG0643	Histidine kinase
CCZ37_06935	COG2198	Histidine kinase
CCZ37_06945	COG0745	RESPONSE REGULATOR receiver
CCZ37_06955	COG1448	Aminotransferase
CCZ37_06960	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CCZ37_06970	COG0840	transmembrane signaling receptor activity
CCZ37_06980	COG1846	Transcriptional regulator
CCZ37_06995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CCZ37_07000	COG3108	Peptidase M15
CCZ37_07005	COG2989	Protein conserved in bacteria
CCZ37_07035	COG1940	carbohydrate kinase activity
CCZ37_07040	COG1629	transport
CCZ37_07040	COG4771	TonB-dependent receptor
CCZ37_07045	COG3023	N-Acetylmuramoyl-L-alanine amidase
CCZ37_07050	COG0748	coenzyme F420 binding
CCZ37_07055	COG3721	Heme iron utilization protein
CCZ37_07065	COG0811	peptide transport
CCZ37_07070	COG0848	biopolymer transport protein
CCZ37_07080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCZ37_07085	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CCZ37_07105	COG1621	beta-fructofuranosidase activity
CCZ37_07115	COG1263	PTS System
CCZ37_07115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CCZ37_07120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCZ37_07125	COG2200	EAL domain
CCZ37_07130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CCZ37_07135	COG0840	transmembrane signaling receptor activity
CCZ37_07140	COG1294	oxidase, subunit
CCZ37_07145	COG1271	oxidase subunit
CCZ37_07165	COG3220	belongs to the UPF0276 family
CCZ37_07185	COG1294	oxidase, subunit
CCZ37_07195	COG0251	oxidation-reduction process
CCZ37_07265	COG1518	maintenance of DNA repeat elements
CCZ37_07320	COG4790	Type iii secretion
CCZ37_07335	COG3710	Transcriptional regulator
CCZ37_07370	COG4789	Type iii secretion
CCZ37_07450	COG3710	Transcriptional regulator
CCZ37_07455	COG2205	protein histidine kinase activity
CCZ37_07455	COG2198	Histidine kinase
CCZ37_07455	COG0784	Response regulator, receiver
CCZ37_07455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCZ37_07465	COG1435	thymidine kinase activity
CCZ37_07470	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CCZ37_07480	COG0500	methyltransferase
CCZ37_07485	COG0189	ligase activity
CCZ37_07485	COG4067	protein conserved in archaea
CCZ37_07500	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CCZ37_07505	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CCZ37_07515	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CCZ37_07520	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CCZ37_07525	COG0745	RESPONSE REGULATOR receiver
CCZ37_07535	COG1609	Transcriptional regulator
CCZ37_07540	COG3070	regulator of competence-specific genes
CCZ37_07560	COG0297	glycogen (starch) synthase activity
CCZ37_07565	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CCZ37_07570	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CCZ37_07580	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CCZ37_07585	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CCZ37_07590	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CCZ37_07595	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CCZ37_07600	COG0542	response to heat
CCZ37_07605	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CCZ37_07610	COG1278	Cold shock
CCZ37_07620	COG1187	pseudouridine synthase activity
CCZ37_07625	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CCZ37_07625	COG0140	phosphoribosyl-ATP diphosphatase activity
CCZ37_07630	COG0107	imidazoleglycerol-phosphate synthase activity
CCZ37_07635	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CCZ37_07640	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CCZ37_07645	COG0131	Imidazoleglycerol-phosphate dehydratase
CCZ37_07645	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CCZ37_07650	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CCZ37_07655	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CCZ37_07665	COG1757	Na H antiporter
CCZ37_07670	COG2916	Histone family protein nucleoid-structuring protein H-NS
CCZ37_07675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCZ37_07685	COG0482	sulfurtransferase activity
CCZ37_07690	COG2915	High frequency lysogenization protein hflD homolog
CCZ37_07695	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CCZ37_07700	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CCZ37_07710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCZ37_07710	COG4191	Histidine kinase
CCZ37_07725	COG3070	regulator of competence-specific genes
CCZ37_07735	COG2431	L-lysine efflux transmembrane transporter activity
CCZ37_07745	COG0076	glutamate decarboxylase activity
CCZ37_07750	COG1737	Transcriptional regulator
CCZ37_07755	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CCZ37_07765	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CCZ37_07775	COG0281	malic enzyme
CCZ37_07785	COG2949	membrane
CCZ37_07800	COG3706	GGDEF domain
CCZ37_07800	COG0745	RESPONSE REGULATOR receiver
CCZ37_07805	COG0492	ferredoxin-NADP+ reductase activity
CCZ37_07810	COG4988	ABC transporter
CCZ37_07815	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CCZ37_07820	COG1187	pseudouridine synthase activity
CCZ37_07825	COG0009	L-threonylcarbamoyladenylate synthase
CCZ37_07830	COG0613	PHP domain protein
CCZ37_07840	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CCZ37_07845	COG0512	Glutamine amidotransferase of anthranilate synthase
CCZ37_07850	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CCZ37_07855	COG0134	indole-3-glycerol-phosphate synthase activity
CCZ37_07855	COG0135	phosphoribosylanthranilate isomerase activity
CCZ37_07860	COG0133	tryptophan synthase activity
CCZ37_07865	COG0159	tryptophan synthase activity
CCZ37_07885	COG1607	acyl-coa hydrolase
CCZ37_07890	COG2350	Protein conserved in bacteria
CCZ37_07900	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CCZ37_07905	COG0583	DNA-binding transcription factor activity
CCZ37_07920	COG2203	Gaf domain
CCZ37_07920	COG2199	diguanylate cyclase activity
CCZ37_07920	COG2200	EAL domain
CCZ37_07925	COG5640	endopeptidase activity
CCZ37_07930	COG1032	radical SAM domain protein
CCZ37_07940	COG2268	Band 7 protein
CCZ37_07950	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CCZ37_07965	COG0300	oxidoreductase activity
CCZ37_07975	COG0501	Belongs to the peptidase M48B family
CCZ37_07985	COG1674	ftsk spoiiie
CCZ37_07990	COG1522	sequence-specific DNA binding
CCZ37_07995	COG0686	Belongs to the AlaDH PNT family
CCZ37_08005	COG0583	DNA-binding transcription factor activity
CCZ37_08020	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CCZ37_08025	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CCZ37_08035	COG0539	negative regulation of cytoplasmic translation
CCZ37_08040	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CCZ37_08045	COG1555	photosystem II stabilization
CCZ37_08050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CCZ37_08055	COG0776	regulation of translation
CCZ37_08060	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CCZ37_08075	COG0544	peptidyl-prolyl cis-trans isomerase activity
CCZ37_08090	COG1653	transport
CCZ37_08095	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CCZ37_08100	COG1760	l-serine dehydratase
CCZ37_08110	COG0513	Belongs to the DEAD box helicase family
CCZ37_08120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CCZ37_08135	COG4628	conserved protein (DUF2132)
CCZ37_08140	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CCZ37_08150	COG0732	type I restriction modification DNA specificity domain
CCZ37_08155	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CCZ37_08170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CCZ37_08175	COG0583	DNA-binding transcription factor activity
CCZ37_08180	COG2951	lytic endotransglycosylase activity
CCZ37_08185	COG3100	YcgL domain-containing protein
CCZ37_08195	COG2894	cell division
CCZ37_08205	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CCZ37_08210	COG0318	PFAM AMP-dependent synthetase and ligase
CCZ37_08215	COG0596	Alpha beta hydrolase
CCZ37_08230	COG1214	PFAM Peptidase M22, glycoprotease
CCZ37_08235	COG1199	ATP-dependent helicase activity
CCZ37_08245	COG0788	formyltetrahydrofolate deformylase activity
CCZ37_08250	COG1902	pentaerythritol trinitrate reductase activity
CCZ37_08250	COG0446	pyridine nucleotide-disulphide oxidoreductase
CCZ37_08255	COG0616	signal peptide processing
CCZ37_08260	COG0252	asparaginase activity
CCZ37_08265	COG3139	Protein of unknown function (DUF1315)
CCZ37_08275	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CCZ37_08290	COG2226	methyltransferase
CCZ37_08315	COG3706	GGDEF domain
CCZ37_08325	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CCZ37_08335	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CCZ37_08340	COG2832	Protein of unknown function (DUF454)
CCZ37_08350	COG0745	RESPONSE REGULATOR receiver
CCZ37_08355	COG0583	DNA-binding transcription factor activity
CCZ37_08365	COG1250	3-hydroxyacyl-CoA dehydrogenase
CCZ37_08365	COG1024	Enoyl-CoA hydratase
CCZ37_08370	COG0183	Belongs to the thiolase family
CCZ37_08385	COG1595	DNA-templated transcription, initiation
CCZ37_08395	COG2067	long-chain fatty acid transport protein
CCZ37_08400	COG2067	long-chain fatty acid transport protein
CCZ37_08405	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CCZ37_08410	COG2982	Protein involved in outer membrane biogenesis
CCZ37_08415	COG0572	uridine kinase
CCZ37_08420	COG0489	protein tyrosine kinase activity
CCZ37_08425	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCZ37_08425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCZ37_08435	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CCZ37_08445	COG4109	DRTGG domain
CCZ37_08450	COG2199	diguanylate cyclase activity
CCZ37_08455	COG0314	molybdopterin synthase activity
CCZ37_08460	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CCZ37_08470	COG0521	Mo-molybdopterin cofactor biosynthetic process
CCZ37_08475	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CCZ37_08480	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CCZ37_08485	COG2198	Histidine kinase
CCZ37_08490	COG2204	response regulator
CCZ37_08495	COG0556	nucleotide-excision repair
CCZ37_08505	COG3706	GGDEF domain
CCZ37_08530	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CCZ37_08535	COG1946	Acyl-CoA thioesterase
CCZ37_08540	COG1522	sequence-specific DNA binding
CCZ37_08580	COG0318	PFAM AMP-dependent synthetase and ligase
CCZ37_08585	COG1441	menaquinone biosynthetic process
CCZ37_08590	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CCZ37_08600	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CCZ37_08605	COG1169	isochorismate synthase
CCZ37_08615	COG0436	Aminotransferase
CCZ37_08620	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CCZ37_08625	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CCZ37_08640	COG0616	signal peptide processing
CCZ37_08645	COG1028	Short-chain dehydrogenase reductase Sdr
CCZ37_08650	COG0784	Response regulator, receiver
CCZ37_08650	COG0835	chemotaxis
CCZ37_08655	COG1940	carbohydrate kinase activity
CCZ37_08665	COG4667	esterase of the alpha-beta hydrolase superfamily
CCZ37_08680	COG0733	neurotransmitter:sodium symporter activity
CCZ37_08690	COG1263	PTS System
CCZ37_08690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CCZ37_08695	COG0084	hydrolase, TatD family'
CCZ37_08700	COG0470	DNA polymerase III
CCZ37_08705	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CCZ37_08710	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CCZ37_08715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CCZ37_08740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CCZ37_08750	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CCZ37_08755	COG1399	metal-binding, possibly nucleic acid-binding protein
CCZ37_08760	COG0424	maF-like protein
CCZ37_08765	COG0564	pseudouridine synthase activity
CCZ37_08770	COG1530	ribonuclease E activity
CCZ37_08780	COG1012	belongs to the aldehyde dehydrogenase family
CCZ37_08780	COG1454	alcohol dehydrogenase
CCZ37_08785	COG2095	MarC family integral membrane protein
CCZ37_08790	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CCZ37_08795	COG1757	Na H antiporter
CCZ37_08815	COG3083	sulfuric ester hydrolase activity
CCZ37_08825	COG0243	molybdopterin cofactor binding
CCZ37_08830	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CCZ37_08845	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CCZ37_08850	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CCZ37_08870	COG2853	Lipoprotein
CCZ37_08885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CCZ37_08890	COG1138	Cytochrome C-type biogenesis protein
CCZ37_08895	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CCZ37_08905	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CCZ37_08910	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CCZ37_08915	COG4133	protoheme IX ABC transporter activity
CCZ37_08925	COG0835	chemotaxis
CCZ37_08935	COG1192	Involved in chromosome partitioning
CCZ37_08940	COG2201	protein-glutamate methylesterase activity
CCZ37_08950	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CCZ37_08965	COG0455	bacterial-type flagellum organization
CCZ37_08975	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CCZ37_08980	COG2062	phosphohistidine phosphatase, SixA
CCZ37_08985	COG1025	Belongs to the peptidase M16 family
CCZ37_08990	COG3102	Protein conserved in bacteria
CCZ37_09015	COG1918	ferrous iron import across plasma membrane
CCZ37_09020	COG4977	sequence-specific DNA binding
CCZ37_09025	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CCZ37_09030	COG1121	(ABC) transporter
CCZ37_09035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CCZ37_09050	COG0508	dehydrogenase complex catalyzes the overall conversion of
CCZ37_09055	COG0567	Dehydrogenase, E1 component
CCZ37_09070	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CCZ37_09075	COG2009	succinate dehydrogenase
CCZ37_09085	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CCZ37_09095	COG0033	Phosphoglucomutase
CCZ37_09100	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CCZ37_09105	COG0596	Alpha beta hydrolase
CCZ37_09115	COG0716	FMN binding
CCZ37_09120	COG1346	cytolysis
CCZ37_09130	COG0583	DNA-binding transcription factor activity
CCZ37_09140	COG0735	belongs to the Fur family
CCZ37_09145	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CCZ37_09150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CCZ37_09155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CCZ37_09160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCZ37_09160	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CCZ37_09165	COG0431	NADPH-dependent FMN reductase
CCZ37_09175	COG3101	peptidyl-lysine hydroxylation
CCZ37_09180	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CCZ37_09185	COG2890	protein-(glutamine-N5) methyltransferase activity
CCZ37_09190	COG2840	Smr protein MutS2
CCZ37_09200	COG1684	flagellar biosynthetic protein fliR
CCZ37_09205	COG1987	bacterial-type flagellum assembly
CCZ37_09255	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CCZ37_09265	COG1677	Flagellar hook-basal body complex protein FliE
CCZ37_09270	COG2204	response regulator
CCZ37_09275	COG4191	Histidine kinase
CCZ37_09280	COG2204	response regulator
CCZ37_09285	COG1516	flagellar protein fliS
CCZ37_09295	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CCZ37_09320	COG2837	iron assimilation
CCZ37_09345	COG1393	Belongs to the ArsC family
CCZ37_09350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CCZ37_09370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CCZ37_09380	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CCZ37_09400	COG4783	chaperone-mediated protein folding
CCZ37_09405	COG1393	Belongs to the ArsC family
CCZ37_09425	COG2233	PERMEase
CCZ37_09430	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CCZ37_09440	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CCZ37_09445	COG2912	Transglutaminase-like superfamily
CCZ37_09450	COG3094	Invasion gene expression up-regulator, SirB
CCZ37_09455	COG2890	protein-(glutamine-N5) methyltransferase activity
CCZ37_09460	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CCZ37_09465	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CCZ37_09470	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CCZ37_09485	COG0193	aminoacyl-tRNA hydrolase activity
CCZ37_09590	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CCZ37_09600	COG1705	Flagellar rod assembly protein muramidase FlgJ
CCZ37_09600	COG3951	Flagellar rod assembly protein muramidase FlgJ
CCZ37_09605	COG1706	bacterial-type flagellum-dependent cell motility
CCZ37_09610	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CCZ37_09615	COG4786	Flagellar basal body rod
CCZ37_09620	COG4787	bacterial-type flagellum-dependent cell motility
CCZ37_09625	COG1749	Flagellar hook protein flgE
CCZ37_09630	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CCZ37_09635	COG1558	bacterial-type flagellum-dependent cell motility
CCZ37_09640	COG1815	bacterial-type flagellum-dependent cell motility
CCZ37_09650	COG0784	Response regulator, receiver
CCZ37_09650	COG0835	chemotaxis
CCZ37_09660	COG2747	anti-sigma28 factor FlgM
CCZ37_09705	COG2608	mercury ion transmembrane transporter activity
CCZ37_09705	COG2217	Heavy metal translocating P-type atpase
CCZ37_09735	COG1187	pseudouridine synthase activity
CCZ37_09740	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CCZ37_09745	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CCZ37_09750	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CCZ37_09755	COG0121	glutamine amidotransferase
CCZ37_09760	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CCZ37_09775	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CCZ37_09785	COG2226	methyltransferase
CCZ37_09795	COG0741	lytic transglycosylase activity
CCZ37_09795	COG1388	LysM domain
CCZ37_09810	COG0347	Belongs to the P(II) protein family
CCZ37_09815	COG3479	Phenolic acid decarboxylase
CCZ37_09825	COG0037	tRNA processing
CCZ37_09830	COG0825	malonyl-CoA metabolic process
CCZ37_09835	COG0587	DNA-directed DNA polymerase activity
CCZ37_09845	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CCZ37_09855	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CCZ37_09860	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CCZ37_09865	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CCZ37_09875	COG0750	zinc metalloprotease
CCZ37_09880	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CCZ37_09885	COG0575	Belongs to the CDS family
CCZ37_09890	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CCZ37_09895	COG0233	cytoplasmic translational termination
CCZ37_09905	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CCZ37_09910	COG0052	Belongs to the universal ribosomal protein uS2 family
CCZ37_09915	COG0024	Methionine aminopeptidase
CCZ37_09920	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CCZ37_09930	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CCZ37_09935	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CCZ37_09960	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CCZ37_09960	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CCZ37_09970	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CCZ37_09995	COG2252	PERMEase
CCZ37_10000	COG2195	Cleaves the N-terminal amino acid of tripeptides
CCZ37_10005	COG0189	ligase activity
CCZ37_10005	COG4067	protein conserved in archaea
CCZ37_10010	COG0189	ligase activity
CCZ37_10020	COG0733	neurotransmitter:sodium symporter activity
CCZ37_10025	COG5001	Diguanylate cyclase
CCZ37_10025	COG4251	negative regulation of phosphorylation
CCZ37_10025	COG3706	GGDEF domain
CCZ37_10025	COG2203	Gaf domain
CCZ37_10035	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CCZ37_10045	COG1477	protein flavinylation
CCZ37_10055	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CCZ37_10080	COG0271	Belongs to the BolA IbaG family
CCZ37_10100	COG2211	Major facilitator Superfamily
CCZ37_10110	COG1595	DNA-templated transcription, initiation
CCZ37_10125	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CCZ37_10130	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CCZ37_10135	COG2166	iron-sulfur cluster assembly
CCZ37_10140	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CCZ37_10145	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CCZ37_10155	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CCZ37_10155	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CCZ37_10165	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CCZ37_10170	COG1074	ATP-dependent DNA helicase activity
CCZ37_10175	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CCZ37_10190	COG3141	response to X-ray
CCZ37_10195	COG2171	N-acyltransferase activity
CCZ37_10225	COG0784	Response regulator, receiver
CCZ37_10225	COG3437	response regulator, receiver
CCZ37_10235	COG4628	conserved protein (DUF2132)
CCZ37_10240	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CCZ37_10245	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CCZ37_10255	COG0560	Phosphoserine phosphatase
CCZ37_10265	COG0813	purine-nucleoside phosphorylase activity
CCZ37_10270	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CCZ37_10280	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CCZ37_10285	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CCZ37_10290	COG0084	hydrolase, TatD family'
CCZ37_10300	COG1115	amino acid carrier protein
CCZ37_10315	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CCZ37_10325	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
CCZ37_10330	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CCZ37_10335	COG0083	homoserine kinase activity
CCZ37_10355	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CCZ37_10360	COG0745	RESPONSE REGULATOR receiver
CCZ37_10365	COG0784	Response regulator, receiver
CCZ37_10365	COG2198	Histidine kinase
CCZ37_10365	COG5002	protein histidine kinase activity
CCZ37_10370	COG1242	4 iron, 4 sulfur cluster binding
CCZ37_10375	COG0070	glutamate synthase
CCZ37_10375	COG0067	glutamate synthase
CCZ37_10375	COG0069	glutamate synthase activity
CCZ37_10385	COG0069	glutamate synthase activity
CCZ37_10385	COG0070	glutamate synthase
CCZ37_10385	COG0067	glutamate synthase
CCZ37_10390	COG0493	'glutamate synthase
CCZ37_10410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CCZ37_10415	COG2860	membrane
CCZ37_10420	COG0730	response to heat
CCZ37_10435	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CCZ37_10455	COG0505	Belongs to the CarA family
CCZ37_10465	COG0494	nUDIX hydrolase
CCZ37_10470	COG0653	protein targeting
CCZ37_10480	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CCZ37_10485	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CCZ37_10490	COG0849	cell division
CCZ37_10495	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CCZ37_10500	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CCZ37_10505	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CCZ37_10510	COG0772	Belongs to the SEDS family
CCZ37_10515	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CCZ37_10520	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CCZ37_10525	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CCZ37_10530	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CCZ37_10535	COG0768	penicillin binding
CCZ37_10540	COG3116	cell division
CCZ37_10555	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CCZ37_10560	COG3107	peptidoglycan biosynthetic process
CCZ37_10570	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CCZ37_10580	COG2969	positive regulation of protein catabolic process
CCZ37_10585	COG0625	glutathione transferase activity
CCZ37_10590	COG2857	Cytochrome c1
CCZ37_10595	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CCZ37_10600	COG0723	plastoquinol--plastocyanin reductase activity
CCZ37_10620	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CCZ37_10625	COG3105	Protein conserved in bacteria
CCZ37_10630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCZ37_10635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCZ37_10640	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CCZ37_10645	COG0187	DNA topoisomerase II activity
CCZ37_10650	COG3150	esterase
CCZ37_10660	COG3151	Protein conserved in bacteria
CCZ37_10665	COG0494	nUDIX hydrolase
CCZ37_10670	COG1538	Outer membrane efflux protein
CCZ37_10680	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CCZ37_10690	COG3025	triphosphatase activity
CCZ37_10695	COG1392	Phosphate transport regulator
CCZ37_10700	COG0306	phosphate transporter
CCZ37_10705	COG4991	sh3 domain protein
CCZ37_10715	COG3267	Type II secretory pathway component ExeA
CCZ37_10715	COG3409	Peptidoglycan-binding domain 1 protein
CCZ37_10720	COG0617	tRNA 3'-terminal CCA addition
CCZ37_10730	COG0504	CTP synthase activity
CCZ37_10735	COG3956	TIGRFAM MazG family protein
CCZ37_10740	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CCZ37_10745	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CCZ37_10750	COG3437	response regulator, receiver
CCZ37_10750	COG3850	Histidine kinase
CCZ37_10750	COG4999	Histidine kinase
CCZ37_10750	COG2205	protein histidine kinase activity
CCZ37_10755	COG0736	holo-[acyl-carrier-protein] synthase activity
CCZ37_10780	COG0681	Belongs to the peptidase S26 family
CCZ37_10785	COG0481	GTPase activity
CCZ37_10790	COG3086	response to oxidative stress
CCZ37_10805	COG1595	DNA-templated transcription, initiation
CCZ37_10810	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CCZ37_10820	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CCZ37_10825	COG0354	folic acid binding
CCZ37_10840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCZ37_10845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCZ37_10855	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CCZ37_10865	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CCZ37_10875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CCZ37_10885	COG0028	Belongs to the TPP enzyme family
CCZ37_10890	COG1022	Amp-dependent synthetase and ligase
CCZ37_10895	COG0583	DNA-binding transcription factor activity
CCZ37_10910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CCZ37_10915	COG0473	3-isopropylmalate dehydrogenase activity
CCZ37_10925	COG0066	3-isopropylmalate dehydratase activity
CCZ37_11025	COG0795	lipopolysaccharide-transporting ATPase activity
CCZ37_11030	COG0795	lipopolysaccharide-transporting ATPase activity
CCZ37_11035	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CCZ37_11040	COG2927	DNA polymerase III (CHI subunit)
CCZ37_11045	COG0525	valine-tRNA ligase activity
CCZ37_11050	COG0564	pseudouridine synthase activity
CCZ37_11060	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CCZ37_11070	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CCZ37_11085	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CCZ37_11090	COG0251	oxidation-reduction process
CCZ37_11095	COG0204	Acyl-transferase
CCZ37_11100	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CCZ37_11105	COG5007	Belongs to the BolA IbaG family
CCZ37_11115	COG2854	intermembrane phospholipid transfer
CCZ37_11120	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CCZ37_11125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CCZ37_11130	COG1127	ABC transporter
CCZ37_11140	COG0517	IMP dehydrogenase activity
CCZ37_11140	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CCZ37_11145	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CCZ37_11155	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CCZ37_11160	COG1137	ATPase activity
CCZ37_11170	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CCZ37_11175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCZ37_11185	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCZ37_11190	COG2239	Acts as a magnesium transporter
CCZ37_11195	COG0312	modulator of DNA gyrase
CCZ37_11200	COG3028	Belongs to the UPF0307 family
CCZ37_11205	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CCZ37_11210	COG1178	ABC-type Fe3 transport system permease component
CCZ37_11215	COG4143	(ABC) transporter
CCZ37_11220	COG0163	prenyltransferase activity
CCZ37_11225	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CCZ37_11230	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CCZ37_11235	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CCZ37_11240	COG2105	PFAM AIG2 family protein
CCZ37_11245	COG2911	Protein conserved in bacteria
CCZ37_11250	COG0729	surface antigen
CCZ37_11255	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CCZ37_11260	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CCZ37_11295	COG0529	Catalyzes the synthesis of activated sulfate
CCZ37_11300	COG2895	sulfate adenylyltransferase (ATP) activity
CCZ37_11310	COG1648	precorrin-2 dehydrogenase activity
CCZ37_11310	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CCZ37_11315	COG0737	Belongs to the 5'-nucleotidase family
CCZ37_11325	COG0513	Belongs to the DEAD box helicase family
CCZ37_11330	COG2153	protein acetylation
CCZ37_11335	COG3061	Opacity-associated protein A
CCZ37_11335	COG3266	domain, Protein
CCZ37_11340	COG0545	Peptidyl-prolyl cis-trans isomerase
CCZ37_11345	COG0203	ribosomal protein L17
CCZ37_11355	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CCZ37_11360	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CCZ37_11365	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CCZ37_11375	COG0201	protein transport
CCZ37_11400	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CCZ37_11405	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CCZ37_11425	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CCZ37_11430	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CCZ37_11455	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CCZ37_11480	COG0051	transcription antitermination factor activity, RNA binding
CCZ37_11485	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CCZ37_11490	COG0557	exoribonuclease II activity
CCZ37_11495	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CCZ37_11505	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CCZ37_11515	COG1047	Peptidyl-prolyl cis-trans
CCZ37_11520	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CCZ37_11530	COG2249	NAD(P)H dehydrogenase (quinone) activity
CCZ37_11535	COG0488	(ABC) transporter
CCZ37_11545	COG0429	hydrolase of the alpha beta-hydrolase fold
CCZ37_11555	COG3954	Phosphoribulokinase
CCZ37_11560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CCZ37_11580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CCZ37_11635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCZ37_11645	COG0583	DNA-binding transcription factor activity
CCZ37_11660	COG0180	Tryptophanyl-tRNA synthetase
CCZ37_11665	COG0546	phosphoglycolate phosphatase activity
CCZ37_11670	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CCZ37_11675	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CCZ37_11690	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CCZ37_11720	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CCZ37_11730	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CCZ37_11730	COG0678	peroxiredoxin activity
CCZ37_11735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CCZ37_11745	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CCZ37_11745	COG0165	Argininosuccinate lyase
CCZ37_11755	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CCZ37_11760	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CCZ37_11780	COG1045	serine acetyltransferase
CCZ37_11795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CCZ37_11800	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CCZ37_11805	COG1053	succinate dehydrogenase
CCZ37_11810	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CCZ37_11815	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CCZ37_11825	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CCZ37_11830	COG1509	lysine 2,3-aminomutase activity
CCZ37_11845	COG0459	protein refolding
CCZ37_11875	COG0149	triose-phosphate isomerase activity
CCZ37_11880	COG0534	Mate efflux family protein
CCZ37_11885	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CCZ37_11890	COG1575	Belongs to the MenA family. Type 1 subfamily
CCZ37_11910	COG1609	Transcriptional regulator
CCZ37_11915	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CCZ37_11925	COG0281	malic enzyme
CCZ37_11935	COG0626	cystathionine gamma-synthase activity
CCZ37_11940	COG0527	aspartate kinase activity
CCZ37_11940	COG0460	homoserine dehydrogenase
CCZ37_11945	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CCZ37_11955	COG1494	fructose-1,6-bisphosphatase
CCZ37_11960	COG0205	6-phosphofructokinase activity
CCZ37_11965	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CCZ37_11975	COG0745	RESPONSE REGULATOR receiver
CCZ37_11980	COG2205	protein histidine kinase activity
CCZ37_11985	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CCZ37_11990	COG1278	Cold shock
CCZ37_12000	COG2199	diguanylate cyclase activity
CCZ37_12005	COG1027	Aspartate ammonia-lyase
CCZ37_12010	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CCZ37_12015	COG1288	antiporter activity
CCZ37_12030	COG0549	Belongs to the carbamate kinase family
CCZ37_12035	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CCZ37_12045	COG0540	Belongs to the ATCase OTCase family
CCZ37_12050	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CCZ37_12055	COG1438	arginine binding
CCZ37_12060	COG4232	protein-disulfide reductase activity
CCZ37_12070	COG3263	regulation of cellular component size
CCZ37_12080	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CCZ37_12085	COG2198	Histidine kinase
CCZ37_12085	COG2205	protein histidine kinase activity
CCZ37_12085	COG0784	Response regulator, receiver
CCZ37_12090	COG2814	Major facilitator Superfamily
CCZ37_12105	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CCZ37_12110	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CCZ37_12115	COG0511	ligase activity, forming carbon-carbon bonds
CCZ37_12120	COG0439	Biotin carboxylase
CCZ37_12125	COG2264	protein methyltransferase activity
CCZ37_12130	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CCZ37_12135	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CCZ37_12145	COG1982	Orn Lys Arg decarboxylase major
CCZ37_12150	COG0531	amino acid
CCZ37_12155	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CCZ37_12160	COG3710	Transcriptional regulator
CCZ37_12165	COG0789	Transcriptional regulator
CCZ37_12175	COG0151	Belongs to the GarS family
CCZ37_12185	COG0776	regulation of translation
CCZ37_12190	COG1253	flavin adenine dinucleotide binding
CCZ37_12200	COG3068	Protein conserved in bacteria
CCZ37_12205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CCZ37_12210	COG0668	transmembrane transport
CCZ37_12215	COG0840	transmembrane signaling receptor activity
CCZ37_12220	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CCZ37_12225	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CCZ37_12230	COG3366	ferrous iron transmembrane transporter activity
CCZ37_12235	COG0700	Nucleoside recognition
CCZ37_12240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CCZ37_12275	COG0438	transferase activity, transferring glycosyl groups
CCZ37_12325	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CCZ37_12355	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CCZ37_12365	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CCZ37_12385	COG1051	belongs to the nudix hydrolase family
CCZ37_12390	COG5433	transposase activity
CCZ37_12430	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CCZ37_12435	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CCZ37_12440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CCZ37_12445	COG0662	Cupin 2, conserved barrel domain protein
CCZ37_12445	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CCZ37_12495	COG0859	PFAM glycosyl transferase family 9
CCZ37_12500	COG1519	Transferase
CCZ37_12505	COG0110	maltose O-acetyltransferase activity
CCZ37_12510	COG1028	Short-chain dehydrogenase reductase Sdr
CCZ37_12515	COG1083	cytidylyl-transferase
CCZ37_12525	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CCZ37_12525	COG0517	IMP dehydrogenase activity
CCZ37_12530	COG0110	maltose O-acetyltransferase activity
CCZ37_12535	COG2089	acid synthase
CCZ37_12540	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CCZ37_12545	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CCZ37_12555	COG3083	sulfuric ester hydrolase activity
CCZ37_12560	COG3642	lipopolysaccharide core region biosynthetic process
CCZ37_12565	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CCZ37_12570	COG0859	PFAM glycosyl transferase family 9
CCZ37_12575	COG0463	Glycosyl transferase, family 2
CCZ37_12580	COG0859	PFAM glycosyl transferase family 9
CCZ37_12585	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CCZ37_12600	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CCZ37_12610	COG2003	Belongs to the UPF0758 family
CCZ37_12620	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CCZ37_12625	COG1309	transcriptional regulator
CCZ37_12630	COG1560	Kdo2-lipid A biosynthetic process
CCZ37_12635	COG1560	Kdo2-lipid A biosynthetic process
CCZ37_12645	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CCZ37_12650	COG1561	YicC-like family, N-terminal region
CCZ37_12660	COG3550	peptidyl-serine autophosphorylation
CCZ37_12665	COG3620	sequence-specific DNA binding
CCZ37_12705	COG1061	Type III restriction enzyme res subunit
CCZ37_12730	COG0612	Peptidase, M16
CCZ37_12745	COG0514	ATP-dependent DNA helicase (RecQ)
CCZ37_12750	COG2962	Rard protein
CCZ37_12755	COG0405	Gamma-glutamyltransferase
CCZ37_12765	COG1280	lysine exporter protein (LysE YggA)
CCZ37_12770	COG0210	DNA helicase
CCZ37_12775	COG0339	signal peptide processing
CCZ37_12780	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CCZ37_12785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CCZ37_12800	COG1566	PFAM secretion protein HlyD family protein
CCZ37_12815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCZ37_12825	COG3008	intermembrane lipid transfer
CCZ37_12825	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CCZ37_12830	COG2995	paraquat-inducible protein a
CCZ37_12860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCZ37_12915	COG1309	transcriptional regulator
CCZ37_12920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCZ37_12925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCZ37_12930	COG2960	long-chain fatty acid transporting porin activity
CCZ37_12940	COG0583	DNA-binding transcription factor activity
CCZ37_12945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CCZ37_12970	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CCZ37_12975	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CCZ37_12975	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CCZ37_12985	COG0084	hydrolase, TatD family'
CCZ37_12995	COG0805	protein transport
CCZ37_13000	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CCZ37_13010	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CCZ37_13025	COG1322	Protein conserved in bacteria
CCZ37_13030	COG0697	spore germination
CCZ37_13040	COG2081	HI0933 family
CCZ37_13055	COG1528	Iron-storage protein
CCZ37_13060	COG0589	response to stress
CCZ37_13065	COG0697	spore germination
CCZ37_13075	COG0742	ribosomal rna small subunit methyltransferase
CCZ37_13080	COG1522	sequence-specific DNA binding
CCZ37_13100	COG0006	proline dipeptidase activity
CCZ37_13100	COG0006	proline dipeptidase activity
CCZ37_13105	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CCZ37_13115	COG2104	thiamine diphosphate biosynthetic process
CCZ37_13125	COG0352	thiamine-phosphate diphosphorylase activity
CCZ37_13145	COG3335	DDE superfamily endonuclease
CCZ37_13185	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CCZ37_13190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CCZ37_13195	COG1739	Uncharacterized protein family UPF0029
CCZ37_13205	COG0183	Belongs to the thiolase family
CCZ37_13210	COG0583	DNA-binding transcription factor activity
CCZ37_13215	COG2814	Major facilitator Superfamily
CCZ37_13225	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CCZ37_13230	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CCZ37_13235	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CCZ37_13240	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CCZ37_13245	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CCZ37_13250	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CCZ37_13260	COG0356	it plays a direct role in the translocation of protons across the membrane
CCZ37_13265	COG3312	ion transport
CCZ37_13270	COG1475	DNA binding
CCZ37_13275	COG1192	Involved in chromosome partitioning
CCZ37_13285	COG0445	tRNA wobble uridine modification
CCZ37_13290	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CCZ37_13300	COG0706	membrane insertase activity
CCZ37_13305	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CCZ37_13320	COG1126	abc transporter atp-binding protein
CCZ37_13340	COG1132	(ABC) transporter
CCZ37_13385	COG0835	chemotaxis
CCZ37_13390	COG0835	chemotaxis
CCZ37_13400	COG0745	RESPONSE REGULATOR receiver
CCZ37_13410	COG1444	tRNA N-acetyltransferase activity
CCZ37_13415	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CCZ37_13455	COG2084	Dehydrogenase
CCZ37_13460	COG0814	amino acid
CCZ37_13490	COG0583	DNA-binding transcription factor activity
CCZ37_13495	COG2910	NAD(P)H-binding
CCZ37_13505	COG3304	Inner membrane component domain
CCZ37_13525	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CCZ37_13550	COG0363	glucosamine-6-phosphate deaminase activity
CCZ37_13560	COG0739	heme binding
CCZ37_13565	COG2213	PTS system mannitol-specific
CCZ37_13565	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCZ37_13570	COG0246	Mannitol dehydrogenase
CCZ37_13575	COG3722	fumarate hydratase activity
CCZ37_13580	COG1301	dicarboxylic acid transport
CCZ37_13585	COG2259	Doxx family
CCZ37_13600	COG1846	Transcriptional regulator
CCZ37_13610	COG3046	protein related to deoxyribodipyrimidine photolyase
CCZ37_13615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CCZ37_13630	COG3842	ATPase activity
CCZ37_13640	COG1176	ABC-type spermidine putrescine transport system, permease component I
CCZ37_13660	COG0513	Belongs to the DEAD box helicase family
CCZ37_13670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CCZ37_13680	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CCZ37_13685	COG1328	CTP reductase activity
CCZ37_13695	COG2130	NADP-dependent
CCZ37_13700	COG1309	transcriptional regulator
CCZ37_13715	COG0745	RESPONSE REGULATOR receiver
CCZ37_13725	COG0564	pseudouridine synthase activity
CCZ37_13810	COG3501	Rhs element vgr protein
CCZ37_13825	COG1869	D-ribose catabolic process
CCZ37_13830	COG1129	ABC transporter
CCZ37_13835	COG1172	Belongs to the binding-protein-dependent transport system permease family
CCZ37_13840	COG1879	ABC-type sugar transport system periplasmic component
CCZ37_13845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCZ37_13850	COG1609	Transcriptional regulator
CCZ37_13870	COG0363	glucosamine-6-phosphate deaminase activity
CCZ37_13875	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CCZ37_13885	COG1067	ATP-dependent peptidase activity
CCZ37_13910	COG3122	Protein conserved in bacteria
CCZ37_13915	COG1230	cation diffusion facilitator family transporter
CCZ37_13925	COG1881	PFAM PEBP family protein
CCZ37_13935	COG1231	oxidoreductase activity
CCZ37_13960	COG1304	FMN binding
CCZ37_13965	COG1620	l-lactate permease
CCZ37_13970	COG0583	DNA-binding transcription factor activity
CCZ37_13975	COG2199	diguanylate cyclase activity
CCZ37_13975	COG2203	Gaf domain
CCZ37_13990	COG3527	Alpha-acetolactate decarboxylase
CCZ37_14000	COG0584	glycerophosphoryl diester phosphodiesterase
CCZ37_14005	COG2271	Major facilitator Superfamily
CCZ37_14010	COG3397	chitin binding
CCZ37_14030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CCZ37_14040	COG2199	diguanylate cyclase activity
CCZ37_14055	COG0659	secondary active sulfate transmembrane transporter activity
CCZ37_14065	COG0739	heme binding
CCZ37_14070	COG5001	Diguanylate cyclase
CCZ37_14075	COG0583	DNA-binding transcription factor activity
CCZ37_14080	COG2814	Major facilitator Superfamily
CCZ37_14100	COG0697	spore germination
CCZ37_14110	COG0179	Fumarylacetoacetate (FAA) hydrolase
CCZ37_14115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CCZ37_14120	COG0765	amino acid transport
CCZ37_14125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCZ37_14130	COG0765	amino acid transport
CCZ37_14140	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CCZ37_14150	COG3123	guanosine phosphorylase activity
CCZ37_14160	COG1741	Belongs to the pirin family
CCZ37_14170	COG5001	Diguanylate cyclase
CCZ37_14200	COG3706	GGDEF domain
CCZ37_14205	COG2315	Protein conserved in bacteria
CCZ37_14210	COG0784	Response regulator, receiver
CCZ37_14210	COG0835	chemotaxis
CCZ37_14215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CCZ37_14225	COG3842	ATPase activity
CCZ37_14240	COG1175	transmembrane transport
CCZ37_14275	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CCZ37_14285	COG0633	Ferredoxin
CCZ37_14285	COG3217	Mosc domain protein beta barrel domain protein
CCZ37_14290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CCZ37_14295	COG2195	Cleaves the N-terminal amino acid of tripeptides
CCZ37_14305	COG3604	Transcriptional regulator
CCZ37_14310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CCZ37_14310	COG1017	nitric oxide dioxygenase activity
CCZ37_14315	COG4681	YaeQ
CCZ37_14320	COG1278	Cold shock
CCZ37_14345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CCZ37_14350	COG0516	GMP reductase activity
CCZ37_14360	COG3335	DDE superfamily endonuclease
CCZ37_14380	COG0714	Associated with various cellular activities
CCZ37_14390	COG2433	Pfam Transposase IS66
CCZ37_14420	COG1132	(ABC) transporter
CCZ37_14425	COG1132	(ABC) transporter
CCZ37_14445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CCZ37_14450	COG1021	2,3-dihydroxybenzoate-AMP ligase
CCZ37_14475	COG2226	methyltransferase
CCZ37_14475	COG3433	isochorismatase activity
CCZ37_14475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCZ37_14480	COG2814	Major facilitator Superfamily
CCZ37_14485	COG4771	TonB-dependent receptor
CCZ37_14490	COG4977	sequence-specific DNA binding
CCZ37_14490	COG1917	Cupin 2, conserved barrel domain protein
CCZ37_14515	COG0589	response to stress
CCZ37_14520	COG0659	secondary active sulfate transmembrane transporter activity
CCZ37_14525	COG0640	Transcriptional regulator
CCZ37_14530	COG0798	PFAM Bile acid sodium symporter
CCZ37_14540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CCZ37_14550	COG0573	inorganic phosphate transmembrane transporter activity
CCZ37_14560	COG0640	Transcriptional regulator
CCZ37_14565	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CCZ37_14600	COG2271	Major facilitator Superfamily
CCZ37_14605	COG3851	Histidine kinase
CCZ37_14610	COG2197	response regulator
CCZ37_14625	COG0346	lactoylglutathione lyase activity
CCZ37_14635	COG0156	8-amino-7-oxononanoate synthase activity
CCZ37_14640	COG1063	alcohol dehydrogenase
CCZ37_14655	COG1063	alcohol dehydrogenase
CCZ37_14695	COG2258	MOSC domain
CCZ37_14710	COG3227	Zinc metalloprotease (Elastase)
CCZ37_14715	COG3530	Putative quorum-sensing-regulated virulence factor
CCZ37_14720	COG1403	HNH endonuclease
CCZ37_14725	COG3706	GGDEF domain
CCZ37_14740	COG2304	oxidoreductase activity
CCZ37_14760	COG0714	Associated with various cellular activities
CCZ37_14775	COG0366	Alpha amylase catalytic
CCZ37_14815	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CCZ37_14825	COG0456	acetyltransferase
CCZ37_14830	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CCZ37_14835	COG0662	Cupin 2, conserved barrel domain protein
CCZ37_14840	COG0527	aspartate kinase activity
CCZ37_14855	COG1166	arginine decarboxylase activity
CCZ37_14860	COG0010	Belongs to the arginase family
CCZ37_14880	COG5001	Diguanylate cyclase
CCZ37_14880	COG3300	MHYT domain
CCZ37_14885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCZ37_14910	COG0484	heat shock protein binding
CCZ37_14920	COG1716	ATPase activity
CCZ37_14920	COG5001	Diguanylate cyclase
CCZ37_14925	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CCZ37_14935	COG4181	ATPase activity
CCZ37_14940	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CCZ37_14950	COG1984	allophanate hydrolase subunit 2
CCZ37_14960	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CCZ37_14965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CCZ37_14970	COG0814	amino acid
CCZ37_14975	COG0513	Belongs to the DEAD box helicase family
CCZ37_14985	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CCZ37_15000	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CCZ37_15035	COG3023	N-Acetylmuramoyl-L-alanine amidase
CCZ37_15045	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CCZ37_15050	COG2146	nitrite reductase [NAD(P)H] activity
CCZ37_15060	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CCZ37_15060	COG1648	precorrin-2 dehydrogenase activity
CCZ37_15065	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CCZ37_15085	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CCZ37_15090	COG0247	lactate metabolic process
CCZ37_15095	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CCZ37_15100	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CCZ37_15105	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CCZ37_15110	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CCZ37_15135	COG2827	Endonuclease containing a URI domain
CCZ37_15145	COG1879	ABC-type sugar transport system periplasmic component
CCZ37_15150	COG5002	protein histidine kinase activity
CCZ37_15150	COG0784	Response regulator, receiver
CCZ37_15180	COG1289	transmembrane transporter activity
CCZ37_15185	COG0210	DNA helicase
CCZ37_15190	COG1803	Methylglyoxal synthase
CCZ37_15195	COG1879	ABC-type sugar transport system periplasmic component
CCZ37_15200	COG2205	protein histidine kinase activity
CCZ37_15200	COG2198	Histidine kinase
CCZ37_15200	COG0784	Response regulator, receiver
CCZ37_15205	COG0469	pyruvate kinase activity
CCZ37_15210	COG2271	Major facilitator Superfamily
CCZ37_15220	COG1840	ABC-type Fe3 transport system, periplasmic component
CCZ37_15235	COG1979	alcohol dehydrogenase
CCZ37_15240	COG2207	Transcriptional regulator
CCZ37_15250	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CCZ37_15255	COG3706	GGDEF domain
CCZ37_15265	COG3111	PFAM Bacterial OB fold (BOF) protein
CCZ37_15270	COG1492	cobalamin metabolic process
CCZ37_15275	COG0725	ABC transporter, periplasmic molybdate-binding protein
CCZ37_15280	COG4149	molybdate abc transporter
CCZ37_15285	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CCZ37_15295	COG5001	Diguanylate cyclase
CCZ37_15295	COG2203	Gaf domain
CCZ37_15295	COG3706	GGDEF domain
CCZ37_15295	COG4251	negative regulation of phosphorylation
CCZ37_15320	COG3852	Histidine kinase
CCZ37_15325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCZ37_15325	COG4191	Histidine kinase
CCZ37_15345	COG0640	Transcriptional regulator
CCZ37_15385	COG1328	CTP reductase activity
CCZ37_15390	COG0602	queuosine metabolic process
CCZ37_15400	COG4067	protein conserved in archaea
CCZ37_15400	COG0189	ligase activity
CCZ37_15415	COG4166	transmembrane transport
CCZ37_15420	COG4174	ABC transporter (Permease)
CCZ37_15425	COG4239	(ABC) transporter, permease
CCZ37_15430	COG4172	Belongs to the ABC transporter superfamily
CCZ37_15440	COG3038	cytochrome b561
CCZ37_15445	COG2353	YceI-like domain
CCZ37_15450	COG0840	transmembrane signaling receptor activity
CCZ37_15455	COG0545	Peptidyl-prolyl cis-trans isomerase
CCZ37_15470	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CCZ37_15485	COG2897	thiosulfate sulfurtransferase activity
CCZ37_15490	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CCZ37_15495	COG0303	'Molybdopterin
CCZ37_15500	COG0302	gtp cyclohydrolase
CCZ37_15505	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CCZ37_15505	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CCZ37_15510	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CCZ37_15515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CCZ37_15520	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CCZ37_15530	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CCZ37_15535	COG1011	Hydrolase
CCZ37_15540	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CCZ37_15545	COG2188	Transcriptional regulator
CCZ37_15560	COG2116	formate transmembrane transporter activity
CCZ37_15565	COG0583	DNA-binding transcription factor activity
CCZ37_15575	COG3593	DNA synthesis involved in DNA repair
CCZ37_15580	COG0737	Belongs to the 5'-nucleotidase family
CCZ37_15585	COG0861	Integral membrane protein TerC family
CCZ37_15595	COG2824	Alkylphosphonate utilization operon protein PhnA
CCZ37_15605	COG2050	protein possibly involved in aromatic compounds catabolism
CCZ37_15620	COG0653	protein targeting
CCZ37_15625	COG0583	DNA-binding transcription factor activity
CCZ37_15630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CCZ37_15630	COG1042	CoA-binding domain protein
CCZ37_15630	COG0045	succinate-CoA ligase (ADP-forming) activity
CCZ37_15640	COG1181	Belongs to the D-alanine--D-alanine ligase family
CCZ37_15655	COG0023	Translation Initiation Factor
CCZ37_15660	COG3140	Belongs to the UPF0181 family
CCZ37_15675	COG0745	RESPONSE REGULATOR receiver
CCZ37_15685	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CCZ37_15690	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CCZ37_15705	COG3706	GGDEF domain
CCZ37_15710	COG1278	Cold shock
CCZ37_15720	COG0724	RNA recognition motif
CCZ37_15735	COG2501	S4 domain
CCZ37_15745	COG0488	(ABC) transporter
CCZ37_15790	COG3555	Aspartyl Asparaginyl beta-hydroxylase
CCZ37_15820	COG2433	Pfam Transposase IS66
CCZ37_15835	COG3093	addiction module antidote protein HigA
CCZ37_15840	COG3549	Plasmid maintenance system killer
CCZ37_15985	COG1028	Short-chain dehydrogenase reductase Sdr
CCZ37_16380	COG2433	Pfam Transposase IS66
CCZ37_16500	COG0489	protein tyrosine kinase activity
CCZ37_16855	COG2433	Pfam Transposase IS66
CCZ37_16885	COG2314	TM2 domain
CCZ37_17160	COG0454	-acetyltransferase
CCZ37_17235	COG0384	phenazine biosynthesis protein PhzF
CCZ37_17245	COG0346	lactoylglutathione lyase activity
CCZ37_17310	COG0346	lactoylglutathione lyase activity
CCZ37_17385	COG3040	lipid binding
CCZ37_17455	COG3041	Addiction module toxin RelE StbE family
CCZ37_17495	COG1028	Short-chain dehydrogenase reductase Sdr
CCZ37_17520	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CCZ37_17525	COG0513	Belongs to the DEAD box helicase family
CCZ37_17530	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CCZ37_17560	COG3069	C4-dicarboxylate transmembrane transporter activity
CCZ37_17565	COG2197	response regulator
CCZ37_17570	COG3850	Histidine kinase
CCZ37_17575	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CCZ37_17585	COG0243	molybdopterin cofactor binding
CCZ37_17595	COG3005	denitrification pathway
CCZ37_17615	COG0183	Belongs to the thiolase family
CCZ37_17625	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CCZ37_17630	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CCZ37_17685	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CCZ37_17700	COG1136	(ABC) transporter
CCZ37_17700	COG0577	efflux transmembrane transporter activity
CCZ37_17710	COG1136	(ABC) transporter
CCZ37_17715	COG0523	cobalamin synthesis protein
CCZ37_17720	COG0038	chloride channel
CCZ37_17730	COG0156	8-amino-7-oxononanoate synthase activity
CCZ37_17735	COG0784	Response regulator, receiver
CCZ37_17735	COG2205	protein histidine kinase activity
CCZ37_17740	COG0419	ATPase involved in DNA repair
CCZ37_17745	COG0420	3'-5' exonuclease activity
CCZ37_17750	COG1609	Transcriptional regulator
CCZ37_17755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCZ37_17755	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCZ37_17760	COG1105	Belongs to the carbohydrate kinase PfkB family
CCZ37_17765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CCZ37_17765	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CCZ37_17765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CCZ37_17805	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CCZ37_17830	COG1012	belongs to the aldehyde dehydrogenase family
CCZ37_17865	COG0753	catalase activity
CCZ37_17890	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CCZ37_17895	COG4604	ABC transporter, ATP-binding protein
CCZ37_17900	COG4605	iron ion homeostasis
CCZ37_17905	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCZ37_17910	COG4607	ABC-type enterochelin transport system periplasmic component
CCZ37_17935	COG4412	M6 family metalloprotease domain protein
CCZ37_17935	COG3291	Pkd domain containing protein
CCZ37_17940	COG5380	lipid catabolic process
CCZ37_17945	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CCZ37_17955	COG3240	lipase activity
CCZ37_17960	COG0443	Heat shock 70 kDa protein
CCZ37_17970	COG2814	Major facilitator Superfamily
CCZ37_17975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCZ37_17975	COG4191	Histidine kinase
CCZ37_17985	COG3437	response regulator, receiver
CCZ37_17985	COG0784	Response regulator, receiver
CCZ37_17990	COG0840	transmembrane signaling receptor activity
CCZ37_18000	COG3186	Phenylalanine-4-hydroxylase
CCZ37_18005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CCZ37_18010	COG0583	DNA-binding transcription factor activity
CCZ37_18020	COG0583	DNA-binding transcription factor activity
CCZ37_18035	COG0110	maltose O-acetyltransferase activity
CCZ37_18040	COG1765	OsmC-like protein
CCZ37_18045	COG0673	inositol 2-dehydrogenase activity
CCZ37_18050	COG0642	Histidine kinase
CCZ37_18055	COG0745	RESPONSE REGULATOR receiver
CCZ37_18060	COG2977	Belongs to the P-Pant transferase superfamily
CCZ37_18070	COG2130	NADP-dependent
CCZ37_18100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CCZ37_18125	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCZ37_18130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCZ37_18170	COG3437	response regulator, receiver
CCZ37_18180	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CCZ37_18190	COG2203	Gaf domain
CCZ37_18190	COG5001	Diguanylate cyclase
CCZ37_18190	COG3706	GGDEF domain
CCZ37_18190	COG4251	negative regulation of phosphorylation
CCZ37_18195	COG4989	oxidoreductase activity
CCZ37_18215	COG2267	carboxylic ester hydrolase activity
CCZ37_18220	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CCZ37_18235	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CCZ37_18245	COG0513	Belongs to the DEAD box helicase family
CCZ37_18255	COG1388	LysM domain
CCZ37_18255	COG1376	ErfK ybiS ycfS ynhG family protein
CCZ37_18260	COG0415	Belongs to the DNA photolyase family
CCZ37_18265	COG0789	Transcriptional regulator
CCZ37_18270	COG3272	Protein of unknown function (DUF1722)
CCZ37_18275	COG0813	purine-nucleoside phosphorylase activity
CCZ37_18290	COG3706	GGDEF domain
CCZ37_18300	COG1566	PFAM secretion protein HlyD family protein
CCZ37_18325	COG0786	glutamate:sodium symporter activity
CCZ37_18340	COG1999	signal sequence binding
CCZ37_18350	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CCZ37_18370	COG4580	involved in the transport of maltose and maltodextrins
CCZ37_18405	COG0561	phosphatase activity
CCZ37_18410	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CCZ37_18415	COG3623	hexulose-6-phosphate isomerase
CCZ37_18430	COG1132	(ABC) transporter
CCZ37_18435	COG4399	Belongs to the UPF0754 family
CCZ37_18440	COG0671	phosphoesterase, PA-phosphatase related
CCZ37_18460	COG0840	transmembrane signaling receptor activity
CCZ37_18470	COG1131	(ABC) transporter
CCZ37_18475	COG2188	Transcriptional regulator
CCZ37_18485	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CCZ37_18490	COG0471	metal ion transport
CCZ37_18535	COG3501	Rhs element vgr protein
CCZ37_18545	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CCZ37_18550	COG1640	4-alpha-glucanotransferase
CCZ37_18555	COG0058	SHG alpha-glucan phosphorylase activity
CCZ37_18560	COG2909	trisaccharide binding
CCZ37_18580	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CCZ37_18600	COG0840	transmembrane signaling receptor activity
CCZ37_18635	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CCZ37_18660	COG2274	protein secretion by the type I secretion system
CCZ37_18670	COG0745	RESPONSE REGULATOR receiver
CCZ37_18670	COG3706	GGDEF domain
CCZ37_18690	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CCZ37_18695	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CCZ37_18700	COG0840	transmembrane signaling receptor activity
CCZ37_18705	COG0835	chemotaxis
CCZ37_18710	COG0835	chemotaxis
CCZ37_18720	COG0745	RESPONSE REGULATOR receiver
CCZ37_18730	COG1444	tRNA N-acetyltransferase activity