locus-tag	class	description
VroAM7_00020	COG0592	DNA-directed DNA polymerase activity
VroAM7_00040	COG0187	DNA topoisomerase II activity
VroAM7_00050	COG0071	Belongs to the small heat shock protein (HSP20) family
VroAM7_00060	COG3977	Valine--pyruvate aminotransferase
VroAM7_00070	COG0366	Alpha amylase catalytic
VroAM7_00100	COG2119	membrane
VroAM7_00120	COG0425	Belongs to the sulfur carrier protein TusA family
VroAM7_00170	COG0604	alcohol dehydrogenase
VroAM7_00180	COG0183	Belongs to the thiolase family
VroAM7_00200	COG1739	Uncharacterized protein family UPF0029
VroAM7_00210	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VroAM7_00250	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
VroAM7_00310	COG0583	DNA-binding transcription factor activity
VroAM7_00320	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
VroAM7_00330	COG2960	long-chain fatty acid transporting porin activity
VroAM7_00340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VroAM7_00350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VroAM7_00360	COG1309	transcriptional regulator
VroAM7_00400	COG4172	Belongs to the ABC transporter superfamily
VroAM7_00410	COG4166	transmembrane transport
VroAM7_00430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VroAM7_00450	COG1609	Transcriptional regulator
VroAM7_00460	COG0583	DNA-binding transcription factor activity
VroAM7_00470	COG2076	Multidrug Resistance protein
VroAM7_00490	COG0129	dihydroxy-acid dehydratase activity
VroAM7_00500	COG3265	gluconokinase activity
VroAM7_00510	COG2610	gluconate transmembrane transporter activity
VroAM7_00520	COG0800	Aldolase
VroAM7_00600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VroAM7_00620	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VroAM7_00640	COG1522	sequence-specific DNA binding
VroAM7_00650	COG5002	protein histidine kinase activity
VroAM7_00650	COG5001	Diguanylate cyclase
VroAM7_00680	COG0697	spore germination
VroAM7_00690	COG0589	response to stress
VroAM7_00700	COG1528	Iron-storage protein
VroAM7_00720	COG2081	HI0933 family
VroAM7_00770	COG0464	growth
VroAM7_00780	COG1404	Belongs to the peptidase S8 family
VroAM7_00820	COG3335	DDE superfamily endonuclease
VroAM7_00830	COG1484	DNA-dependent DNA replication
VroAM7_00960	COG4974	Belongs to the 'phage' integrase family
VroAM7_01020	COG1322	Protein conserved in bacteria
VroAM7_01040	COG3165	ubiquinone biosynthetic process from chorismate
VroAM7_01080	COG0805	protein transport
VroAM7_01100	COG0084	hydrolase, TatD family'
VroAM7_01130	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VroAM7_01130	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VroAM7_01140	COG0218	Necessary for normal cell division and for the maintenance of normal septation
VroAM7_01190	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VroAM7_01200	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VroAM7_01220	COG2204	response regulator
VroAM7_01230	COG3852	Histidine kinase
VroAM7_01250	COG0174	glutamine synthetase
VroAM7_01310	COG1490	D-aminoacyl-tRNA deacylase activity
VroAM7_01320	COG0456	acetyltransferase
VroAM7_01360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VroAM7_01370	COG3031	protein transport across the cell outer membrane
VroAM7_01390	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VroAM7_01400	COG1459	type II secretion system
VroAM7_01410	COG2165	general secretion pathway protein
VroAM7_01420	COG2165	general secretion pathway protein
VroAM7_01430	COG2165	general secretion pathway protein
VroAM7_01440	COG4795	General secretion pathway protein
VroAM7_01450	COG3156	type II secretion system protein K
VroAM7_01460	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VroAM7_01470	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VroAM7_01500	COG1218	3'(2'),5'-bisphosphate nucleotidase
VroAM7_01510	COG0494	nUDIX hydrolase
VroAM7_01550	COG2183	response to ionizing radiation
VroAM7_01570	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VroAM7_01580	COG0745	RESPONSE REGULATOR receiver
VroAM7_01590	COG2205	protein histidine kinase activity
VroAM7_01600	COG2233	PERMEase
VroAM7_01610	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VroAM7_01620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VroAM7_01630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VroAM7_01640	COG1758	RNA polymerase activity
VroAM7_01650	COG0194	GDP metabolic process
VroAM7_01680	COG0848	biopolymer transport protein
VroAM7_01690	COG0811	peptide transport
VroAM7_01730	COG4174	ABC transporter (Permease)
VroAM7_01740	COG4239	(ABC) transporter, permease
VroAM7_01750	COG0747	negative chemotaxis
VroAM7_01760	COG0444	Belongs to the ABC transporter superfamily
VroAM7_01770	COG4608	Belongs to the ABC transporter superfamily
VroAM7_01840	COG1561	YicC-like family, N-terminal region
VroAM7_01850	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
VroAM7_01870	COG1560	Kdo2-lipid A biosynthetic process
VroAM7_01880	COG1309	transcriptional regulator
VroAM7_01890	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
VroAM7_01910	COG2003	Belongs to the UPF0758 family
VroAM7_01920	COG0227	Belongs to the bacterial ribosomal protein bL28 family
VroAM7_01970	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
VroAM7_02000	COG0463	Glycosyl transferase, family 2
VroAM7_02010	COG0859	PFAM glycosyl transferase family 9
VroAM7_02020	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VroAM7_02030	COG3642	lipopolysaccharide core region biosynthetic process
VroAM7_02050	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
VroAM7_02070	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VroAM7_02120	COG1519	Transferase
VroAM7_02130	COG0859	PFAM glycosyl transferase family 9
VroAM7_02150	COG1560	Kdo2-lipid A biosynthetic process
VroAM7_02170	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VroAM7_02240	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VroAM7_02250	COG1459	type II secretion system
VroAM7_02330	COG1450	Type ii and iii secretion system protein
VroAM7_02380	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
VroAM7_02410	COG2089	acid synthase
VroAM7_02430	COG1215	transferase activity, transferring glycosyl groups
VroAM7_02480	COG0367	asparagine synthase
VroAM7_02490	COG0438	transferase activity, transferring glycosyl groups
VroAM7_02500	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VroAM7_02520	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VroAM7_02540	COG1215	transferase activity, transferring glycosyl groups
VroAM7_02600	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
VroAM7_02620	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
VroAM7_02650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
VroAM7_02680	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
VroAM7_02690	COG0149	triose-phosphate isomerase activity
VroAM7_02740	COG1494	fructose-1,6-bisphosphatase
VroAM7_02760	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VroAM7_02770	COG1575	Belongs to the MenA family. Type 1 subfamily
VroAM7_02810	COG1609	Transcriptional regulator
VroAM7_02820	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VroAM7_02860	COG0088	Forms part of the polypeptide exit tunnel
VroAM7_03000	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
VroAM7_03030	COG1841	ribosomal large subunit assembly
VroAM7_03040	COG0200	Binds to the 23S rRNA
VroAM7_03050	COG0201	protein transport
VroAM7_03060	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VroAM7_03070	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VroAM7_03100	COG0203	ribosomal protein L17
VroAM7_03120	COG0545	Peptidyl-prolyl cis-trans isomerase
VroAM7_03150	COG2153	protein acetylation
VroAM7_03160	COG0513	Belongs to the DEAD box helicase family
VroAM7_03180	COG0737	Belongs to the 5'-nucleotidase family
VroAM7_03190	COG1648	precorrin-2 dehydrogenase activity
VroAM7_03190	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VroAM7_03220	COG0471	metal ion transport
VroAM7_03220	COG3273	potassium ion transport
VroAM7_03230	COG0529	Catalyzes the synthesis of activated sulfate
VroAM7_03270	COG1136	(ABC) transporter
VroAM7_03290	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VroAM7_03310	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VroAM7_03320	COG0729	surface antigen
VroAM7_03340	COG2105	PFAM AIG2 family protein
VroAM7_03360	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
VroAM7_03380	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VroAM7_03390	COG0163	prenyltransferase activity
VroAM7_03400	COG4143	(ABC) transporter
VroAM7_03410	COG1178	ABC-type Fe3 transport system permease component
VroAM7_03420	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
VroAM7_03490	COG0142	geranyltranstransferase activity
VroAM7_03500	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VroAM7_03530	COG2966	Psort location CytoplasmicMembrane, score
VroAM7_03540	COG3610	response to peptide
VroAM7_03550	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
VroAM7_03590	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
VroAM7_03600	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VroAM7_03610	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
VroAM7_03620	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VroAM7_03660	COG0473	3-isopropylmalate dehydrogenase activity
VroAM7_03670	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
VroAM7_03710	COG0583	DNA-binding transcription factor activity
VroAM7_03720	COG1022	Amp-dependent synthetase and ligase
VroAM7_03740	COG0028	Belongs to the TPP enzyme family
VroAM7_03750	COG0440	acetolactate synthase activity
VroAM7_03760	COG3706	GGDEF domain
VroAM7_03780	COG0469	pyruvate kinase activity
VroAM7_03790	COG1349	DNA-binding transcription factor activity
VroAM7_03800	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
VroAM7_03830	COG5002	protein histidine kinase activity
VroAM7_03870	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VroAM7_03880	COG0358	DNA primase activity
VroAM7_03890	COG1610	YqeY-like protein
VroAM7_03900	COG0828	Belongs to the bacterial ribosomal protein bS21 family
VroAM7_03910	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
VroAM7_03920	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
VroAM7_03930	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
VroAM7_03940	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
VroAM7_03950	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VroAM7_03980	COG3409	Peptidoglycan-binding domain 1 protein
VroAM7_03980	COG3267	Type II secretory pathway component ExeA
VroAM7_04010	COG4991	sh3 domain protein
VroAM7_04020	COG0306	phosphate transporter
VroAM7_04030	COG1392	Phosphate transport regulator
VroAM7_04040	COG3025	triphosphatase activity
VroAM7_04050	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VroAM7_04070	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VroAM7_04090	COG1538	Outer membrane efflux protein
VroAM7_04100	COG0494	nUDIX hydrolase
VroAM7_04110	COG3151	Protein conserved in bacteria
VroAM7_04130	COG3150	esterase
VroAM7_04140	COG0187	DNA topoisomerase II activity
VroAM7_04150	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
VroAM7_04160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VroAM7_04170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VroAM7_04180	COG3105	Protein conserved in bacteria
VroAM7_04190	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VroAM7_04220	COG0723	plastoquinol--plastocyanin reductase activity
VroAM7_04230	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VroAM7_04240	COG2857	Cytochrome c1
VroAM7_04250	COG0625	glutathione transferase activity
VroAM7_04260	COG2969	positive regulation of protein catabolic process
VroAM7_04270	COG2823	Periplasmic or secreted lipoprotein
VroAM7_04280	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VroAM7_04310	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VroAM7_04330	COG3116	cell division
VroAM7_04340	COG0768	penicillin binding
VroAM7_04350	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VroAM7_04360	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VroAM7_04370	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
VroAM7_04390	COG0772	Belongs to the SEDS family
VroAM7_04420	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VroAM7_04430	COG0849	cell division
VroAM7_04440	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VroAM7_04450	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
VroAM7_04480	COG0494	nUDIX hydrolase
VroAM7_04500	COG0505	Belongs to the CarA family
VroAM7_04510	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VroAM7_04540	COG0730	response to heat
VroAM7_04550	COG0583	DNA-binding transcription factor activity
VroAM7_04560	COG2860	membrane
VroAM7_04610	COG0493	'glutamate synthase
VroAM7_04620	COG0070	glutamate synthase
VroAM7_04620	COG0069	glutamate synthase activity
VroAM7_04620	COG0067	glutamate synthase
VroAM7_04640	COG0067	glutamate synthase
VroAM7_04640	COG0070	glutamate synthase
VroAM7_04640	COG0069	glutamate synthase activity
VroAM7_04650	COG1242	4 iron, 4 sulfur cluster binding
VroAM7_04660	COG2203	Gaf domain
VroAM7_04660	COG3706	GGDEF domain
VroAM7_04660	COG4251	negative regulation of phosphorylation
VroAM7_04660	COG5001	Diguanylate cyclase
VroAM7_04670	COG5002	protein histidine kinase activity
VroAM7_04670	COG0784	Response regulator, receiver
VroAM7_04670	COG2198	Histidine kinase
VroAM7_04690	COG0745	RESPONSE REGULATOR receiver
VroAM7_04710	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VroAM7_04740	COG0083	homoserine kinase activity
VroAM7_04750	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
VroAM7_04820	COG1115	amino acid carrier protein
VroAM7_04830	COG3022	response to hydroperoxide
VroAM7_04860	COG0513	Belongs to the DEAD box helicase family
VroAM7_04890	COG0716	FMN binding
VroAM7_04910	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VroAM7_04920	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VroAM7_04930	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
VroAM7_04970	COG0667	Aldo Keto reductase
VroAM7_05010	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
VroAM7_05020	COG0730	response to heat
VroAM7_05050	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
VroAM7_05090	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
VroAM7_05120	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VroAM7_05130	COG0732	type I restriction modification DNA specificity domain
VroAM7_05140	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
VroAM7_05170	COG2801	Transposase and inactivated derivatives
VroAM7_05250	COG1283	sodium-dependent phosphate transmembrane transporter activity
VroAM7_05270	COG0583	DNA-binding transcription factor activity
VroAM7_05280	COG0640	Transcriptional regulator
VroAM7_05290	COG0268	Binds directly to 16S ribosomal RNA
VroAM7_05300	COG0728	peptidoglycan biosynthetic process
VroAM7_05310	COG0196	riboflavin kinase activity
VroAM7_05340	COG1047	Peptidyl-prolyl cis-trans
VroAM7_05350	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VroAM7_05360	COG3279	Response regulator of the LytR AlgR family
VroAM7_05370	COG3275	phosphorelay sensor kinase activity
VroAM7_05380	COG1966	Carbon starvation protein
VroAM7_05420	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VroAM7_05430	COG1472	Belongs to the glycosyl hydrolase 3 family
VroAM7_05440	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VroAM7_05450	COG1605	Chorismate mutase
VroAM7_05450	COG0287	Prephenate dehydrogenase
VroAM7_05460	COG0739	heme binding
VroAM7_05480	COG0488	(ABC) transporter
VroAM7_05510	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
VroAM7_05520	COG1605	Chorismate mutase
VroAM7_05520	COG0077	Prephenate dehydratase
VroAM7_05530	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VroAM7_05540	COG0741	lytic transglycosylase activity
VroAM7_05550	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VroAM7_05560	COG0564	pseudouridine synthase activity
VroAM7_05580	COG0542	response to heat
VroAM7_05610	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
VroAM7_05680	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
VroAM7_05700	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VroAM7_05730	COG0745	RESPONSE REGULATOR receiver
VroAM7_05740	COG5002	protein histidine kinase activity
VroAM7_05760	COG0248	Ppx GppA phosphatase
VroAM7_05770	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
VroAM7_05780	COG0573	inorganic phosphate transmembrane transporter activity
VroAM7_05790	COG0581	inorganic phosphate transmembrane transporter activity
VroAM7_05800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VroAM7_05810	COG0704	Plays a role in the regulation of phosphate uptake
VroAM7_05870	COG0450	alkyl hydroperoxide reductase
VroAM7_05880	COG0583	DNA-binding transcription factor activity
VroAM7_05890	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
VroAM7_05910	COG0517	IMP dehydrogenase activity
VroAM7_05960	COG1862	Preprotein translocase
VroAM7_05970	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VroAM7_05980	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VroAM7_05990	COG0483	inositol monophosphate 1-phosphatase activity
VroAM7_06030	COG0822	iron-sulfur transferase activity
VroAM7_06040	COG0316	Belongs to the HesB IscA family
VroAM7_06070	COG0633	Ferredoxin
VroAM7_06080	COG2975	iron-sulfur cluster assembly
VroAM7_06150	COG2976	Protein conserved in bacteria
VroAM7_06160	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VroAM7_06190	COG2199	diguanylate cyclase activity
VroAM7_06190	COG2203	Gaf domain
VroAM7_06210	COG0517	IMP dehydrogenase activity
VroAM7_06210	COG0516	GMP reductase activity
VroAM7_06230	COG1757	Na H antiporter
VroAM7_06250	COG1584	GPR1 FUN34 yaaH family protein
VroAM7_06260	COG1115	amino acid carrier protein
VroAM7_06280	COG0583	DNA-binding transcription factor activity
VroAM7_06300	COG2873	o-acetylhomoserine
VroAM7_06310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
VroAM7_06360	COG1289	transmembrane transporter activity
VroAM7_06370	COG0583	DNA-binding transcription factor activity
VroAM7_06390	COG2867	negative regulation of translational initiation
VroAM7_06400	COG2914	Belongs to the UPF0125 (RnfH) family
VroAM7_06410	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VroAM7_06430	COG0497	DNA recombination
VroAM7_06470	COG1301	dicarboxylic acid transport
VroAM7_06540	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VroAM7_06550	COG0590	tRNA wobble adenosine to inosine editing
VroAM7_06570	COG0047	phosphoribosylformylglycinamidine synthase activity
VroAM7_06570	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VroAM7_06610	COG2195	Cleaves the N-terminal amino acid of tripeptides
VroAM7_06620	COG2252	PERMEase
VroAM7_06670	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
VroAM7_06680	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VroAM7_06690	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VroAM7_06690	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VroAM7_06740	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
VroAM7_06750	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VroAM7_06770	COG0142	geranyltranstransferase activity
VroAM7_06790	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VroAM7_06820	COG0583	DNA-binding transcription factor activity
VroAM7_06840	COG2363	Small membrane protein
VroAM7_06870	COG1611	Belongs to the LOG family
VroAM7_06880	COG0745	RESPONSE REGULATOR receiver
VroAM7_06880	COG3706	GGDEF domain
VroAM7_06920	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
VroAM7_06930	COG0737	Belongs to the 5'-nucleotidase family
VroAM7_06950	COG1464	Belongs to the NlpA lipoprotein family
VroAM7_06960	COG2011	ABC-type metal ion transport system permease component
VroAM7_06970	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
VroAM7_06980	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VroAM7_07000	COG1263	PTS System
VroAM7_07000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VroAM7_07010	COG0366	Alpha amylase catalytic
VroAM7_07020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
VroAM7_07030	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VroAM7_07070	COG1686	Belongs to the peptidase S11 family
VroAM7_07080	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VroAM7_07090	COG0772	Belongs to the SEDS family
VroAM7_07100	COG0768	penicillin binding
VroAM7_07120	COG0799	negative regulation of ribosome biogenesis
VroAM7_07130	COG1466	dna polymerase III delta subunit
VroAM7_07140	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
VroAM7_07160	COG2888	peptidyl-tyrosine sulfation
VroAM7_07170	COG0815	Transfers the fatty acyl group on membrane lipoproteins
VroAM7_07180	COG4535	Mg2 and Co2 transporter CorC
VroAM7_07200	COG1702	phosphate starvation-inducible protein PhoH
VroAM7_07220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VroAM7_07250	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VroAM7_07300	COG2890	protein-(glutamine-N5) methyltransferase activity
VroAM7_07310	COG3094	Invasion gene expression up-regulator, SirB
VroAM7_07320	COG2912	Transglutaminase-like superfamily
VroAM7_07340	COG0737	Belongs to the 5'-nucleotidase family
VroAM7_07350	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
VroAM7_07360	COG1187	pseudouridine synthase activity
VroAM7_07370	COG2840	Smr protein MutS2
VroAM7_07440	COG2217	Heavy metal translocating P-type atpase
VroAM7_07440	COG2608	mercury ion transmembrane transporter activity
VroAM7_07540	COG2747	anti-sigma28 factor FlgM
VroAM7_07560	COG0784	Response regulator, receiver
VroAM7_07560	COG0835	chemotaxis
VroAM7_07570	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VroAM7_07580	COG1815	bacterial-type flagellum-dependent cell motility
VroAM7_07590	COG1558	bacterial-type flagellum-dependent cell motility
VroAM7_07600	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
VroAM7_07610	COG1749	Flagellar hook protein flgE
VroAM7_07620	COG4787	bacterial-type flagellum-dependent cell motility
VroAM7_07630	COG4786	Flagellar basal body rod
VroAM7_07640	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VroAM7_07650	COG1706	bacterial-type flagellum-dependent cell motility
VroAM7_07660	COG3951	Flagellar rod assembly protein muramidase FlgJ
VroAM7_07660	COG1705	Flagellar rod assembly protein muramidase FlgJ
VroAM7_07690	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VroAM7_07700	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VroAM7_07710	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VroAM7_07720	COG2190	(PTS) system
VroAM7_07730	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
VroAM7_07740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VroAM7_07750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VroAM7_07760	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
VroAM7_07830	COG0330	HflC and HflK could
VroAM7_07840	COG2194	sulfuric ester hydrolase activity
VroAM7_07890	COG1215	transferase activity, transferring glycosyl groups
VroAM7_07900	COG1215	transferase activity, transferring glycosyl groups
VroAM7_07910	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
VroAM7_07920	COG0457	Tetratricopeptide repeat
VroAM7_07920	COG3118	belongs to the thioredoxin family
VroAM7_07930	COG3118	belongs to the thioredoxin family
VroAM7_07950	COG0300	oxidoreductase activity
VroAM7_07960	COG1090	epimerase
VroAM7_08020	COG0622	Phosphoesterase
VroAM7_08060	COG3710	Transcriptional regulator
VroAM7_08090	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VroAM7_08100	COG3104	oligopeptide transport
VroAM7_08110	COG0250	Participates in transcription elongation, termination and antitermination
VroAM7_08120	COG0367	asparagine synthase
VroAM7_08130	COG4651	solute:proton antiporter activity
VroAM7_08130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VroAM7_08140	COG1940	carbohydrate kinase activity
VroAM7_08140	COG1846	Transcriptional regulator
VroAM7_08150	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VroAM7_08160	COG2190	(PTS) system
VroAM7_08160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VroAM7_08160	COG1263	PTS System
VroAM7_08190	COG0735	belongs to the Fur family
VroAM7_08230	COG0596	Alpha beta hydrolase
VroAM7_08250	COG0033	Phosphoglucomutase
VroAM7_08270	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VroAM7_08290	COG2009	succinate dehydrogenase
VroAM7_08300	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
VroAM7_08310	COG1053	succinate dehydrogenase
VroAM7_08330	COG0567	Dehydrogenase, E1 component
VroAM7_08340	COG0508	dehydrogenase complex catalyzes the overall conversion of
VroAM7_08370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VroAM7_08380	COG1121	(ABC) transporter
VroAM7_08390	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
VroAM7_08410	COG1918	ferrous iron import across plasma membrane
VroAM7_08470	COG3102	Protein conserved in bacteria
VroAM7_08480	COG0788	formyltetrahydrofolate deformylase activity
VroAM7_08500	COG1199	ATP-dependent helicase activity
VroAM7_08510	COG1214	PFAM Peptidase M22, glycoprotease
VroAM7_08540	COG2267	carboxylic ester hydrolase activity
VroAM7_08550	COG0318	PFAM AMP-dependent synthetase and ligase
VroAM7_08560	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
VroAM7_08570	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
VroAM7_08580	COG2894	cell division
VroAM7_08600	COG3100	YcgL domain-containing protein
VroAM7_08610	COG2951	lytic endotransglycosylase activity
VroAM7_08630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VroAM7_08640	COG2852	Protein conserved in bacteria
VroAM7_08660	COG4974	Belongs to the 'phage' integrase family
VroAM7_08710	COG1028	Short-chain dehydrogenase reductase Sdr
VroAM7_08720	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VroAM7_08780	COG2986	histidine ammonia-lyase
VroAM7_08790	COG1216	Glycosyl transferase, family 2
VroAM7_08830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VroAM7_08840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VroAM7_08900	COG2226	methyltransferase
VroAM7_08960	COG3501	Rhs element vgr protein
VroAM7_09060	COG1181	Belongs to the D-alanine--D-alanine ligase family
VroAM7_09100	COG1716	ATPase activity
VroAM7_09150	COG0515	serine threonine protein kinase
VroAM7_09150	COG3064	Membrane
VroAM7_09150	COG4991	sh3 domain protein
VroAM7_09170	COG2169	Transcriptional regulator
VroAM7_09180	COG1253	flavin adenine dinucleotide binding
VroAM7_09190	COG0513	Belongs to the DEAD box helicase family
VroAM7_09200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VroAM7_09210	COG0569	domain protein
VroAM7_09220	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VroAM7_09250	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VroAM7_09260	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VroAM7_09270	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VroAM7_09340	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VroAM7_09350	COG0776	regulation of translation
VroAM7_09360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VroAM7_09370	COG1555	photosystem II stabilization
VroAM7_09410	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
VroAM7_09420	COG0436	Aminotransferase
VroAM7_09430	COG1169	isochorismate synthase
VroAM7_09450	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
VroAM7_09460	COG1441	menaquinone biosynthetic process
VroAM7_09490	COG2855	membrane
VroAM7_09540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VroAM7_09590	COG1522	sequence-specific DNA binding
VroAM7_09610	COG1946	Acyl-CoA thioesterase
VroAM7_09620	COG3126	Type III secretion system lipoprotein chaperone (YscW)
VroAM7_09660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VroAM7_09670	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
VroAM7_09680	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
VroAM7_09690	COG0517	IMP dehydrogenase activity
VroAM7_09690	COG0516	GMP reductase activity
VroAM7_09710	COG2217	Heavy metal translocating P-type atpase
VroAM7_09750	COG0537	adenosine 5'-monophosphoramidase activity
VroAM7_09810	COG1943	Transposase
VroAM7_09820	COG1252	NADH dehydrogenase
VroAM7_09830	COG3385	transposase activity
VroAM7_09860	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
VroAM7_09880	COG4591	ABC-type transport system involved in lipoprotein release permease component
VroAM7_09890	COG1136	(ABC) transporter
VroAM7_09900	COG4591	ABC-type transport system involved in lipoprotein release permease component
VroAM7_09920	COG0658	competence protein
VroAM7_09920	COG2333	competence protein COMEC
VroAM7_09930	COG1132	(ABC) transporter
VroAM7_09970	COG2719	SpoVR family
VroAM7_09980	COG2718	Belongs to the UPF0229 family
VroAM7_09990	COG2766	serine protein kinase
VroAM7_10010	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VroAM7_10030	COG1882	Formate acetyltransferase
VroAM7_10080	COG4215	(ABC) transporter
VroAM7_10100	COG0708	Exodeoxyribonuclease III
VroAM7_10120	COG3923	Primosomal replication protein n
VroAM7_10130	COG0730	response to heat
VroAM7_10140	COG1199	ATP-dependent helicase activity
VroAM7_10160	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VroAM7_10170	COG1187	pseudouridine synthase activity
VroAM7_10190	COG1278	Cold shock
VroAM7_10210	COG0542	response to heat
VroAM7_10230	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VroAM7_10290	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VroAM7_10300	COG1943	Transposase
VroAM7_10310	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VroAM7_10320	COG0297	glycogen (starch) synthase activity
VroAM7_10360	COG3070	regulator of competence-specific genes
VroAM7_10390	COG0745	RESPONSE REGULATOR receiver
VroAM7_10400	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VroAM7_10420	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VroAM7_10440	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
VroAM7_10450	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
VroAM7_10490	COG4067	protein conserved in archaea
VroAM7_10490	COG0189	ligase activity
VroAM7_10520	COG1801	Protein of unknown function DUF72
VroAM7_10540	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
VroAM7_10560	COG0840	transmembrane signaling receptor activity
VroAM7_10570	COG0632	four-way junction helicase activity
VroAM7_10590	COG1271	oxidase subunit
VroAM7_10600	COG1294	oxidase, subunit
VroAM7_10620	COG0824	Thioesterase
VroAM7_10630	COG0811	peptide transport
VroAM7_10660	COG0823	Involved in the tonB-independent uptake of proteins
VroAM7_10670	COG2885	chlorophyll binding
VroAM7_10680	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
VroAM7_10710	COG3766	membrane
VroAM7_10730	COG0754	glutathionylspermidine amidase activity
VroAM7_10760	COG1858	cytochrome C peroxidase
VroAM7_10800	COG0784	Response regulator, receiver
VroAM7_10800	COG5002	protein histidine kinase activity
VroAM7_10840	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VroAM7_10850	COG0732	type I restriction modification DNA specificity domain
VroAM7_10870	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
VroAM7_10880	COG1401	restriction endodeoxyribonuclease activity
VroAM7_10900	COG1620	l-lactate permease
VroAM7_10910	COG0247	lactate metabolic process
VroAM7_10920	COG1139	Iron-sulfur cluster binding protein
VroAM7_10930	COG1556	Lactate utilization protein
VroAM7_10940	COG0583	DNA-binding transcription factor activity
VroAM7_10960	COG2824	Alkylphosphonate utilization operon protein PhnA
VroAM7_11030	COG1136	(ABC) transporter
VroAM7_11080	COG2801	Transposase and inactivated derivatives
VroAM7_11110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VroAM7_11120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VroAM7_11190	COG0840	transmembrane signaling receptor activity
VroAM7_11220	COG1943	Transposase
VroAM7_11230	COG3009	Protein conserved in bacteria
VroAM7_11240	COG3008	intermembrane lipid transfer
VroAM7_11240	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VroAM7_11250	COG2995	paraquat-inducible protein a
VroAM7_11260	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VroAM7_11290	COG4232	protein-disulfide reductase activity
VroAM7_11300	COG3118	belongs to the thioredoxin family
VroAM7_11310	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VroAM7_11350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VroAM7_11370	COG1136	(ABC) transporter
VroAM7_11370	COG0577	efflux transmembrane transporter activity
VroAM7_11380	COG0577	efflux transmembrane transporter activity
VroAM7_11380	COG1136	(ABC) transporter
VroAM7_11390	COG1136	(ABC) transporter
VroAM7_11390	COG0577	efflux transmembrane transporter activity
VroAM7_11400	COG2176	DNA-directed DNA polymerase activity
VroAM7_11460	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
VroAM7_11500	COG1172	Belongs to the binding-protein-dependent transport system permease family
VroAM7_11510	COG1172	Belongs to the binding-protein-dependent transport system permease family
VroAM7_11520	COG1129	ABC transporter
VroAM7_11590	COG5002	protein histidine kinase activity
VroAM7_11590	COG3850	Histidine kinase
VroAM7_11600	COG0745	RESPONSE REGULATOR receiver
VroAM7_11610	COG0463	Glycosyl transferase, family 2
VroAM7_11620	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
VroAM7_11640	COG2964	Protein conserved in bacteria
VroAM7_11670	COG0446	pyridine nucleotide-disulphide oxidoreductase
VroAM7_11680	COG1032	radical SAM domain protein
VroAM7_11690	COG2203	Gaf domain
VroAM7_11690	COG5001	Diguanylate cyclase
VroAM7_11690	COG4251	negative regulation of phosphorylation
VroAM7_11690	COG3706	GGDEF domain
VroAM7_11720	COG0583	DNA-binding transcription factor activity
VroAM7_11750	COG2350	Protein conserved in bacteria
VroAM7_11760	COG1607	acyl-coa hydrolase
VroAM7_11800	COG1301	dicarboxylic acid transport
VroAM7_11810	COG0159	tryptophan synthase activity
VroAM7_11830	COG0135	phosphoribosylanthranilate isomerase activity
VroAM7_11830	COG0134	indole-3-glycerol-phosphate synthase activity
VroAM7_11850	COG0512	Glutamine amidotransferase of anthranilate synthase
VroAM7_11860	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VroAM7_11870	COG0613	PHP domain protein
VroAM7_11880	COG0009	L-threonylcarbamoyladenylate synthase
VroAM7_11900	COG1187	pseudouridine synthase activity
VroAM7_11940	COG0417	DNA replication proofreading
VroAM7_11970	COG2197	response regulator
VroAM7_11980	COG0322	excinuclease ABC activity
VroAM7_12020	COG0019	diaminopimelate decarboxylase activity
VroAM7_12060	COG3385	transposase activity
VroAM7_12090	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VroAM7_12100	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VroAM7_12110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VroAM7_12150	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
VroAM7_12170	COG0437	4 iron, 4 sulfur cluster binding
VroAM7_12180	COG3301	Polysulphide reductase, NrfD
VroAM7_12190	COG1138	Cytochrome C-type biogenesis protein
VroAM7_12200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VroAM7_12210	COG4235	cytochrome complex assembly
VroAM7_12210	COG3088	subunit of a heme lyase
VroAM7_12220	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VroAM7_12270	COG2989	Protein conserved in bacteria
VroAM7_12280	COG3108	Peptidase M15
VroAM7_12290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VroAM7_12300	COG1943	Transposase
VroAM7_12330	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VroAM7_12380	COG1846	Transcriptional regulator
VroAM7_12390	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VroAM7_12400	COG0840	transmembrane signaling receptor activity
VroAM7_12440	COG1448	Aminotransferase
VroAM7_12450	COG2770	Histidine kinase
VroAM7_12450	COG3437	response regulator, receiver
VroAM7_12480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VroAM7_12510	COG0017	Asparaginyl-tRNA synthetase
VroAM7_12520	COG0840	transmembrane signaling receptor activity
VroAM7_12530	COG0720	synthase
VroAM7_12540	COG0531	amino acid
VroAM7_12550	COG1280	lysine exporter protein (LysE YggA)
VroAM7_12560	COG1560	Kdo2-lipid A biosynthetic process
VroAM7_12570	COG0471	metal ion transport
VroAM7_12580	COG4191	Histidine kinase
VroAM7_12580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VroAM7_12600	COG3706	GGDEF domain
VroAM7_12610	COG5001	Diguanylate cyclase
VroAM7_12630	COG1280	lysine exporter protein (LysE YggA)
VroAM7_12640	COG1328	CTP reductase activity
VroAM7_12650	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VroAM7_12670	COG0861	Integral membrane protein TerC family
VroAM7_12690	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VroAM7_12700	COG4221	oxidoreductase activity
VroAM7_12710	COG3706	GGDEF domain
VroAM7_12730	COG1454	alcohol dehydrogenase
VroAM7_12740	COG0814	amino acid
VroAM7_12770	COG1120	ATPase activity
VroAM7_12780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VroAM7_12790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VroAM7_12800	COG4774	siderophore transport
VroAM7_12820	COG1132	(ABC) transporter
VroAM7_12830	COG1132	(ABC) transporter
VroAM7_12850	COG0583	DNA-binding transcription factor activity
VroAM7_12860	COG0583	DNA-binding transcription factor activity
VroAM7_13000	COG1368	sulfuric ester hydrolase activity
VroAM7_13010	COG0215	cysteine-tRNA ligase activity
VroAM7_13020	COG0534	Mate efflux family protein
VroAM7_13030	COG2113	Glycine betaine
VroAM7_13040	COG4176	ABC-type proline glycine betaine transport system permease component
VroAM7_13060	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
VroAM7_13080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VroAM7_13090	COG0456	acetyltransferase
VroAM7_13100	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VroAM7_13110	COG0662	Cupin 2, conserved barrel domain protein
VroAM7_13120	COG0527	aspartate kinase activity
VroAM7_13130	COG1858	cytochrome C peroxidase
VroAM7_13190	COG0583	DNA-binding transcription factor activity
VroAM7_13240	COG0443	Heat shock 70 kDa protein
VroAM7_13250	COG0443	Heat shock 70 kDa protein
VroAM7_13270	COG2199	diguanylate cyclase activity
VroAM7_13350	COG0243	molybdopterin cofactor binding
VroAM7_13360	COG0437	4 iron, 4 sulfur cluster binding
VroAM7_13370	COG3302	dmso reductase anchor subunit
VroAM7_13380	COG3381	protein complex oligomerization
VroAM7_13400	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
VroAM7_13410	COG1643	Atp-dependent helicase
VroAM7_13440	COG0813	purine-nucleoside phosphorylase activity
VroAM7_13490	COG2195	Cleaves the N-terminal amino acid of tripeptides
VroAM7_13570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VroAM7_13580	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VroAM7_13590	COG2909	trisaccharide binding
VroAM7_13660	COG1280	lysine exporter protein (LysE YggA)
VroAM7_13680	COG1115	amino acid carrier protein
VroAM7_13730	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
VroAM7_13750	COG0625	glutathione transferase activity
VroAM7_13760	COG1028	Short-chain dehydrogenase reductase Sdr
VroAM7_13800	COG0589	response to stress
VroAM7_13810	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
VroAM7_13820	COG0668	transmembrane transport
VroAM7_13830	COG3247	response to pH
VroAM7_13850	COG1846	Transcriptional regulator
VroAM7_13890	COG0110	maltose O-acetyltransferase activity
VroAM7_13930	COG3850	Histidine kinase
VroAM7_13930	COG2205	protein histidine kinase activity
VroAM7_13930	COG3437	response regulator, receiver
VroAM7_13930	COG4999	Histidine kinase
VroAM7_13950	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VroAM7_13960	COG1215	transferase activity, transferring glycosyl groups
VroAM7_13970	COG0438	transferase activity, transferring glycosyl groups
VroAM7_13990	COG0438	transferase activity, transferring glycosyl groups
VroAM7_14030	COG0438	transferase activity, transferring glycosyl groups
VroAM7_14050	COG2204	response regulator
VroAM7_14110	COG1793	dna ligase
VroAM7_14130	COG0534	Mate efflux family protein
VroAM7_14140	COG0307	riboflavin synthase, alpha
VroAM7_14170	COG2201	protein-glutamate methylesterase activity
VroAM7_14180	COG3706	GGDEF domain
VroAM7_14200	COG0791	NLP P60 protein
VroAM7_14210	COG0840	transmembrane signaling receptor activity
VroAM7_14220	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VroAM7_14220	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VroAM7_14230	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VroAM7_14240	COG1943	Transposase
VroAM7_14260	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
VroAM7_14270	COG0372	Belongs to the citrate synthase family
VroAM7_14290	COG2828	Protein conserved in bacteria
VroAM7_14340	COG0561	phosphatase activity
VroAM7_14350	COG0602	queuosine metabolic process
VroAM7_14370	COG3706	GGDEF domain
VroAM7_14420	COG3047	cAMP biosynthetic process
VroAM7_14420	COG2885	chlorophyll binding
VroAM7_14460	COG0840	transmembrane signaling receptor activity
VroAM7_14470	COG1254	Belongs to the acylphosphatase family
VroAM7_14480	COG2920	part of a sulfur-relay system
VroAM7_14490	COG0670	Belongs to the BI1 family
VroAM7_14500	COG1126	abc transporter atp-binding protein
VroAM7_14510	COG0765	amino acid transport
VroAM7_14520	COG4597	amino acid ABC transporter
VroAM7_14530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VroAM7_14560	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VroAM7_14610	COG3008	intermembrane lipid transfer
VroAM7_14620	COG2995	paraquat-inducible protein a
VroAM7_14640	COG1132	(ABC) transporter
VroAM7_14650	COG1956	GAF domain-containing protein
VroAM7_14660	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
VroAM7_14690	COG0308	aminopeptidase N
VroAM7_14700	COG2902	Dehydrogenase
VroAM7_14780	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VroAM7_14790	COG1067	ATP-dependent peptidase activity
VroAM7_14840	COG2205	protein histidine kinase activity
VroAM7_14840	COG0784	Response regulator, receiver
VroAM7_14870	COG3278	Belongs to the heme-copper respiratory oxidase family
VroAM7_14900	COG2010	Cytochrome c
VroAM7_14920	COG2217	Heavy metal translocating P-type atpase
VroAM7_14950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VroAM7_14960	COG0589	response to stress
VroAM7_15010	COG3842	ATPase activity
VroAM7_15020	COG1176	ABC-type spermidine putrescine transport system, permease component I
VroAM7_15030	COG1177	transmembrane transport
VroAM7_15040	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VroAM7_15050	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VroAM7_15060	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VroAM7_15110	COG3209	COG3209 Rhs family protein
VroAM7_15140	COG0437	4 iron, 4 sulfur cluster binding
VroAM7_15150	COG0243	molybdopterin cofactor binding
VroAM7_15150	COG3383	formate dehydrogenase (NAD+) activity
VroAM7_15170	COG3381	protein complex oligomerization
VroAM7_15210	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VroAM7_15260	COG0488	(ABC) transporter
VroAM7_15300	COG4191	Histidine kinase
VroAM7_15310	COG2204	response regulator
VroAM7_15330	COG4662	Binding-protein-dependent transport system inner membrane component
VroAM7_15340	COG3842	ATPase activity
VroAM7_15360	COG0303	'Molybdopterin
VroAM7_15390	COG1940	carbohydrate kinase activity
VroAM7_15520	COG0730	response to heat
VroAM7_15530	COG0840	transmembrane signaling receptor activity
VroAM7_15550	COG3437	response regulator, receiver
VroAM7_15560	COG1012	belongs to the aldehyde dehydrogenase family
VroAM7_15570	COG3284	Transcriptional regulator
VroAM7_15640	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
VroAM7_15650	COG0363	glucosamine-6-phosphate deaminase activity
VroAM7_15660	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VroAM7_15670	COG4977	sequence-specific DNA binding
VroAM7_15680	COG4774	siderophore transport
VroAM7_15690	COG4565	transcriptional regulatory protein
VroAM7_15700	COG3290	protein histidine kinase activity
VroAM7_15740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VroAM7_15770	COG1320	monovalent cation:proton antiporter activity
VroAM7_15780	COG2212	antiporter activity
VroAM7_15820	COG2111	Na H antiporter
VroAM7_15820	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VroAM7_15840	COG0589	response to stress
VroAM7_16030	COG4245	von Willebrand factor, type A
VroAM7_16040	COG3335	DDE superfamily endonuclease
VroAM7_16070	COG0494	nUDIX hydrolase
VroAM7_16570	COG0681	Belongs to the peptidase S26 family
VroAM7_16690	COG2026	Addiction module toxin, RelE StbE family
VroAM7_16750	COG0242	peptide deformylase activity
VroAM7_16920	COG2314	TM2 domain
VroAM7_16970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VroAM7_17000	COG3106	COG3106 Predicted ATPase
VroAM7_17030	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VroAM7_17040	COG2205	protein histidine kinase activity
VroAM7_17040	COG2198	Histidine kinase
VroAM7_17040	COG0784	Response regulator, receiver
VroAM7_17060	COG0494	nUDIX hydrolase
VroAM7_17070	COG0814	amino acid
VroAM7_17080	COG1760	l-serine dehydratase
VroAM7_17090	COG5001	Diguanylate cyclase
VroAM7_17090	COG3300	MHYT domain
VroAM7_17120	COG2197	response regulator
VroAM7_17150	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
VroAM7_17160	COG3063	Type IV pilus biogenesis stability protein PilW
VroAM7_17200	COG1451	nucleotide metabolic process
VroAM7_17210	COG3475	LICD family
VroAM7_17220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VroAM7_17230	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VroAM7_17270	COG1566	PFAM secretion protein HlyD family protein
VroAM7_17290	COG0583	DNA-binding transcription factor activity
VroAM7_17360	COG4139	cobalamin transport
VroAM7_17410	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
VroAM7_17430	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
VroAM7_17440	COG0702	epimerase
VroAM7_17450	COG2925	Exonuclease
VroAM7_17470	COG1346	cytolysis
VroAM7_17550	COG0072	phenylalanine-tRNA ligase activity
VroAM7_17550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VroAM7_17570	COG3706	GGDEF domain
VroAM7_17570	COG0745	RESPONSE REGULATOR receiver
VroAM7_17620	COG0251	oxidation-reduction process
VroAM7_17660	COG0291	Belongs to the bacterial ribosomal protein bL35 family
VroAM7_17710	COG2188	Transcriptional regulator
VroAM7_17730	COG0010	Belongs to the arginase family
VroAM7_17750	COG2986	histidine ammonia-lyase
VroAM7_17780	COG0247	lactate metabolic process
VroAM7_17780	COG0277	FAD linked oxidase domain protein
VroAM7_17890	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
VroAM7_17900	COG1643	Atp-dependent helicase
VroAM7_17920	COG2949	membrane
VroAM7_17930	COG0471	metal ion transport
VroAM7_17940	COG3706	GGDEF domain
VroAM7_17940	COG0745	RESPONSE REGULATOR receiver
VroAM7_17980	COG0492	ferredoxin-NADP+ reductase activity
VroAM7_17990	COG4988	ABC transporter
VroAM7_18000	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
VroAM7_18020	COG2610	gluconate transmembrane transporter activity
VroAM7_18030	COG0583	DNA-binding transcription factor activity
VroAM7_18060	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VroAM7_18080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VroAM7_18080	COG4191	Histidine kinase
VroAM7_18110	COG3070	regulator of competence-specific genes
VroAM7_18130	COG2431	L-lysine efflux transmembrane transporter activity
VroAM7_18150	COG0076	glutamate decarboxylase activity
VroAM7_18160	COG1737	Transcriptional regulator
VroAM7_18180	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VroAM7_18200	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VroAM7_18270	COG0534	Mate efflux family protein
VroAM7_18280	COG0702	epimerase
VroAM7_18290	COG4667	esterase of the alpha-beta hydrolase superfamily
VroAM7_18310	COG2814	Major facilitator Superfamily
VroAM7_18320	COG1187	pseudouridine synthase activity
VroAM7_18330	COG1061	Type III restriction enzyme res subunit
VroAM7_18350	COG0745	RESPONSE REGULATOR receiver
VroAM7_18360	COG2205	protein histidine kinase activity
VroAM7_18380	COG1216	Glycosyl transferase, family 2
VroAM7_18380	COG0463	Glycosyl transferase, family 2
VroAM7_18450	COG0659	secondary active sulfate transmembrane transporter activity
VroAM7_18500	COG0493	'glutamate synthase
VroAM7_18520	COG0398	Pfam SNARE associated Golgi protein
VroAM7_18530	COG4134	Bacterial extracellular solute-binding protein
VroAM7_18540	COG4135	transport system, permease component
VroAM7_18550	COG4136	ATPase activity
VroAM7_18560	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VroAM7_18580	COG3604	Transcriptional regulator
VroAM7_18590	COG1151	hydroxylamine reductase activity
VroAM7_18600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VroAM7_18620	COG0564	pseudouridine synthase activity
VroAM7_18640	COG0733	neurotransmitter:sodium symporter activity
VroAM7_18660	COG0626	cystathionine gamma-synthase activity
VroAM7_18680	COG2818	Glycosylase
VroAM7_18740	COG1842	Phage shock protein A
VroAM7_18750	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
VroAM7_18770	COG4168	peptide transport system, permease
VroAM7_18780	COG4171	peptide transport system, permease
VroAM7_18800	COG4172	Belongs to the ABC transporter superfamily
VroAM7_18820	COG1227	inorganic diphosphatase activity
VroAM7_18850	COG0243	molybdopterin cofactor binding
VroAM7_18860	COG3005	denitrification pathway
VroAM7_18870	COG4459	periplasmic nitrate reductase
VroAM7_18880	COG0390	transport system, permease component
VroAM7_18900	COG2116	formate transmembrane transporter activity
VroAM7_18950	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VroAM7_18960	COG1435	thymidine kinase activity
VroAM7_18970	COG0215	cysteine-tRNA ligase activity
VroAM7_18980	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VroAM7_18990	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VroAM7_19000	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VroAM7_19010	COG3012	SEC-C Motif Domain Protein
VroAM7_19020	COG0140	phosphoribosyl-ATP diphosphatase activity
VroAM7_19020	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
VroAM7_19030	COG0107	imidazoleglycerol-phosphate synthase activity
VroAM7_19040	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
VroAM7_19050	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VroAM7_19060	COG0131	Imidazoleglycerol-phosphate dehydratase
VroAM7_19060	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VroAM7_19080	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
VroAM7_19110	COG1757	Na H antiporter
VroAM7_19130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VroAM7_19150	COG0482	sulfurtransferase activity
VroAM7_19170	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VroAM7_19190	COG2268	Band 7 protein
VroAM7_19210	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VroAM7_19240	COG0300	oxidoreductase activity
VroAM7_19290	COG2226	methyltransferase
VroAM7_19320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
VroAM7_19330	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
VroAM7_19370	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VroAM7_19390	COG1674	ftsk spoiiie
VroAM7_19410	COG0686	Belongs to the AlaDH PNT family
VroAM7_19430	COG0583	DNA-binding transcription factor activity
VroAM7_19460	COG4166	transmembrane transport
VroAM7_19480	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VroAM7_19490	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
VroAM7_19510	COG0539	negative regulation of cytoplasmic translation
VroAM7_19530	COG0616	signal peptide processing
VroAM7_19540	COG1028	Short-chain dehydrogenase reductase Sdr
VroAM7_19580	COG0835	chemotaxis
VroAM7_19580	COG0784	Response regulator, receiver
VroAM7_19590	COG1940	carbohydrate kinase activity
VroAM7_19600	COG0469	pyruvate kinase activity
VroAM7_19610	COG4667	esterase of the alpha-beta hydrolase superfamily
VroAM7_19630	COG0733	neurotransmitter:sodium symporter activity
VroAM7_19650	COG1263	PTS System
VroAM7_19650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VroAM7_19660	COG0084	hydrolase, TatD family'
VroAM7_19690	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VroAM7_19750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VroAM7_19780	COG1399	metal-binding, possibly nucleic acid-binding protein
VroAM7_19790	COG0424	maF-like protein
VroAM7_19810	COG0564	pseudouridine synthase activity
VroAM7_19820	COG1530	ribonuclease E activity
VroAM7_19840	COG0659	secondary active sulfate transmembrane transporter activity
VroAM7_19850	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VroAM7_19860	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
VroAM7_19890	COG0489	protein tyrosine kinase activity
VroAM7_19920	COG2186	Transcriptional regulator
VroAM7_19930	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VroAM7_19940	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
VroAM7_19960	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VroAM7_19970	COG3706	GGDEF domain
VroAM7_19980	COG0366	Alpha amylase catalytic
VroAM7_19990	COG1122	ATPase activity
VroAM7_20000	COG4120	Belongs to the binding-protein-dependent transport system permease family
VroAM7_20040	COG0280	phosphate acetyltransferase
VroAM7_20040	COG0857	belongs to the CobB CobQ family
VroAM7_20050	COG3174	membrane
VroAM7_20060	COG0435	Glutathione S-transferase
VroAM7_20080	COG0444	Belongs to the ABC transporter superfamily
VroAM7_20090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VroAM7_20100	COG0601	transmembrane transport
VroAM7_20130	COG0314	molybdopterin synthase activity
VroAM7_20140	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VroAM7_20160	COG0521	Mo-molybdopterin cofactor biosynthetic process
VroAM7_20170	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VroAM7_20180	COG0391	Required for morphogenesis under gluconeogenic growth conditions
VroAM7_20190	COG2198	Histidine kinase
VroAM7_20200	COG2204	response regulator
VroAM7_20210	COG0556	nucleotide-excision repair
VroAM7_20220	COG4657	Part of a membrane complex involved in electron transport
VroAM7_20240	COG4656	Part of a membrane complex involved in electron transport
VroAM7_20250	COG4658	electron transport chain
VroAM7_20260	COG4659	FMN binding
VroAM7_20270	COG4660	Part of a membrane complex involved in electron transport
VroAM7_20280	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VroAM7_20290	COG0346	lactoylglutathione lyase activity
VroAM7_20310	COG2885	chlorophyll binding
VroAM7_20330	COG2056	Na+-H+ antiporter family
VroAM7_20350	COG0784	Response regulator, receiver
VroAM7_20350	COG5002	protein histidine kinase activity
VroAM7_20350	COG2205	protein histidine kinase activity
VroAM7_20360	COG3385	transposase activity
VroAM7_20380	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VroAM7_20420	COG1454	alcohol dehydrogenase
VroAM7_20420	COG1012	belongs to the aldehyde dehydrogenase family
VroAM7_20430	COG2095	MarC family integral membrane protein
VroAM7_20440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VroAM7_20460	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VroAM7_20470	COG1757	Na H antiporter
VroAM7_20520	COG3083	sulfuric ester hydrolase activity
VroAM7_20530	COG2214	Heat shock protein DnaJ domain protein
VroAM7_20550	COG0443	Heat shock 70 kDa protein
VroAM7_20560	COG0123	including yeast histone deacetylase and acetoin utilization protein
VroAM7_20590	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VroAM7_20600	COG0778	Nitroreductase
VroAM7_20610	COG0446	pyridine nucleotide-disulphide oxidoreductase
VroAM7_20610	COG1902	pentaerythritol trinitrate reductase activity
VroAM7_20620	COG0616	signal peptide processing
VroAM7_20630	COG0252	asparaginase activity
VroAM7_20640	COG3139	Protein of unknown function (DUF1315)
VroAM7_20660	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VroAM7_20670	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VroAM7_20730	COG2226	methyltransferase
VroAM7_20770	COG1785	Belongs to the alkaline phosphatase family
VroAM7_20810	COG0668	transmembrane transport
VroAM7_20820	COG2261	transglycosylase associated protein
VroAM7_20830	COG2983	Belongs to the UPF0260 family
VroAM7_20850	COG2964	Protein conserved in bacteria
VroAM7_20870	COG0251	oxidation-reduction process
VroAM7_20880	COG0814	amino acid
VroAM7_20890	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VroAM7_20900	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
VroAM7_20910	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
VroAM7_20920	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
VroAM7_20940	COG2832	Protein of unknown function (DUF454)
VroAM7_20950	COG0745	RESPONSE REGULATOR receiver
VroAM7_20960	COG0583	DNA-binding transcription factor activity
VroAM7_20970	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VroAM7_20980	COG1286	toxin biosynthetic process
VroAM7_20990	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
VroAM7_21000	COG0285	dihydrofolate synthase activity
VroAM7_21050	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VroAM7_21060	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VroAM7_21070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VroAM7_21110	COG3101	peptidyl-lysine hydroxylation
VroAM7_21120	COG2860	membrane
VroAM7_21130	COG1028	Short-chain dehydrogenase reductase Sdr
VroAM7_21140	COG0583	DNA-binding transcription factor activity
VroAM7_21160	COG2890	protein-(glutamine-N5) methyltransferase activity
VroAM7_21170	COG2840	Smr protein MutS2
VroAM7_21180	COG2062	phosphohistidine phosphatase, SixA
VroAM7_21220	COG0183	Belongs to the thiolase family
VroAM7_21250	COG2067	long-chain fatty acid transport protein
VroAM7_21260	COG2067	long-chain fatty acid transport protein
VroAM7_21270	COG2853	Lipoprotein
VroAM7_21300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VroAM7_21310	COG1138	Cytochrome C-type biogenesis protein
VroAM7_21340	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VroAM7_21350	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VroAM7_21360	COG4133	protoheme IX ABC transporter activity
VroAM7_21380	COG0835	chemotaxis
VroAM7_21400	COG1192	Involved in chromosome partitioning
VroAM7_21410	COG2201	protein-glutamate methylesterase activity
VroAM7_21420	COG0643	Histidine kinase
VroAM7_21420	COG2198	Histidine kinase
VroAM7_21430	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
VroAM7_21460	COG0455	bacterial-type flagellum organization
VroAM7_21500	COG1684	flagellar biosynthetic protein fliR
VroAM7_21510	COG1987	bacterial-type flagellum assembly
VroAM7_21560	COG1580	Controls the rotational direction of flagella during chemotaxis
VroAM7_21610	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VroAM7_21630	COG1677	Flagellar hook-basal body complex protein FliE
VroAM7_21640	COG2204	response regulator
VroAM7_21650	COG4191	Histidine kinase
VroAM7_21660	COG2204	response regulator
VroAM7_21670	COG1516	flagellar protein fliS
VroAM7_21690	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VroAM7_21700	COG1334	flagellar protein FlaG
VroAM7_21710	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VroAM7_21720	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VroAM7_21730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VroAM7_21740	COG2211	Major facilitator Superfamily
VroAM7_21750	COG1486	melibiose metabolic process
VroAM7_21760	COG2169	Transcriptional regulator
VroAM7_21770	COG2837	iron assimilation
VroAM7_21820	COG1393	Belongs to the ArsC family
VroAM7_21870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VroAM7_21880	COG2716	regulation of RNA biosynthetic process
VroAM7_21890	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VroAM7_21950	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VroAM7_22040	COG0583	DNA-binding transcription factor activity
VroAM7_22050	COG0697	spore germination
VroAM7_22080	COG3706	GGDEF domain
VroAM7_22120	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VroAM7_22150	COG4783	chaperone-mediated protein folding
VroAM7_22160	COG1393	Belongs to the ArsC family
VroAM7_22200	COG2233	PERMEase
VroAM7_22210	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VroAM7_22230	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
VroAM7_22240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VroAM7_22250	COG0121	glutamine amidotransferase
VroAM7_22260	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VroAM7_22270	COG1960	acyl-CoA dehydrogenase activity
VroAM7_22300	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VroAM7_22320	COG2226	methyltransferase
VroAM7_22330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VroAM7_22340	COG0741	lytic transglycosylase activity
VroAM7_22340	COG1388	LysM domain
VroAM7_22370	COG0347	Belongs to the P(II) protein family
VroAM7_22410	COG0587	DNA-directed DNA polymerase activity
VroAM7_22440	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VroAM7_22460	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VroAM7_22470	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
VroAM7_22490	COG0750	zinc metalloprotease
VroAM7_22510	COG0575	Belongs to the CDS family
VroAM7_22520	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
VroAM7_22570	COG0024	Methionine aminopeptidase
VroAM7_22600	COG0564	pseudouridine synthase activity
VroAM7_22610	COG3098	single-species biofilm formation
VroAM7_22680	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VroAM7_22700	COG1720	tRNA m6t6A37 methyltransferase activity
VroAM7_22750	COG0733	neurotransmitter:sodium symporter activity
VroAM7_22770	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VroAM7_22780	COG0514	ATP-dependent DNA helicase (RecQ)
VroAM7_22790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
VroAM7_22800	COG3706	GGDEF domain
VroAM7_22800	COG0745	RESPONSE REGULATOR receiver
VroAM7_22820	COG1477	protein flavinylation
VroAM7_22840	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VroAM7_22890	COG0271	Belongs to the BolA IbaG family
VroAM7_22950	COG1595	DNA-templated transcription, initiation
VroAM7_22980	COG3248	Nucleoside-binding outer membrane protein
VroAM7_22990	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VroAM7_23000	COG0693	protein deglycase activity
VroAM7_23010	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VroAM7_23020	COG2166	iron-sulfur cluster assembly
VroAM7_23030	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VroAM7_23040	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
VroAM7_23060	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VroAM7_23060	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VroAM7_23080	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VroAM7_23090	COG1074	ATP-dependent DNA helicase activity
VroAM7_23100	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VroAM7_23140	COG3141	response to X-ray
VroAM7_23190	COG2171	N-acyltransferase activity
VroAM7_23200	COG0584	glycerophosphoryl diester phosphodiesterase
VroAM7_23210	COG2271	Major facilitator Superfamily
VroAM7_23220	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VroAM7_23240	COG1349	DNA-binding transcription factor activity
VroAM7_23250	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VroAM7_23260	COG3064	Membrane
VroAM7_23300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VroAM7_23310	COG1609	Transcriptional regulator
VroAM7_23320	COG2017	converts alpha-aldose to the beta-anomer
VroAM7_23340	COG1085	galactose-1-phosphate uridylyltransferase
VroAM7_23350	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VroAM7_23360	COG0768	penicillin binding
VroAM7_23370	COG1609	Transcriptional regulator
VroAM7_23380	COG3250	beta-galactosidase activity
VroAM7_23390	COG2731	YhcH YjgK YiaL family protein
VroAM7_23400	COG0531	amino acid
VroAM7_23410	COG0583	DNA-binding transcription factor activity
VroAM7_23420	COG2059	Chromate
VroAM7_23530	COG4964	Belongs to the GSP D family
VroAM7_23590	COG1022	Amp-dependent synthetase and ligase
VroAM7_23610	COG0583	DNA-binding transcription factor activity
VroAM7_23620	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VroAM7_23630	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VroAM7_23650	COG0560	Phosphoserine phosphatase
VroAM7_23670	COG0813	purine-nucleoside phosphorylase activity
VroAM7_23690	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
VroAM7_23700	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
VroAM7_23710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VroAM7_23720	COG0084	hydrolase, TatD family'
VroAM7_23920	COG2003	Belongs to the UPF0758 family
VroAM7_23970	COG0714	Associated with various cellular activities
VroAM7_24010	COG0629	single-stranded DNA binding
VroAM7_24080	COG0681	Belongs to the peptidase S26 family
VroAM7_24110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VroAM7_24360	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VroAM7_24400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VroAM7_24470	COG3706	GGDEF domain
VroAM7_24510	COG3153	acetyltransferase
VroAM7_24570	COG0534	Mate efflux family protein
VroAM7_24610	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VroAM7_24650	COG0195	Participates in both transcription termination and antitermination
VroAM7_24670	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VroAM7_24690	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
VroAM7_24700	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VroAM7_24720	COG1534	Rna-binding protein
VroAM7_24730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VroAM7_24740	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VroAM7_24750	COG2027	D-alanyl-D-alanine carboxypeptidase
VroAM7_24770	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VroAM7_24780	COG0739	heme binding
VroAM7_24790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VroAM7_24810	COG0316	Belongs to the HesB IscA family
VroAM7_24830	COG0628	permease
VroAM7_24860	COG0747	negative chemotaxis
VroAM7_24880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VroAM7_24890	COG0444	Belongs to the ABC transporter superfamily
VroAM7_24900	COG4608	Belongs to the ABC transporter superfamily
VroAM7_24920	COG2971	BadF BadG BcrA BcrD
VroAM7_24950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VroAM7_24960	COG3842	ATPase activity
VroAM7_24980	COG1840	ABC-type Fe3 transport system, periplasmic component
VroAM7_24990	COG0004	ammonium transporteR
VroAM7_25030	COG1049	propionate catabolic process, 2-methylcitrate cycle
VroAM7_25040	COG1752	Esterase of the alpha-beta hydrolase superfamily
VroAM7_25050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VroAM7_25060	COG1643	Atp-dependent helicase
VroAM7_25080	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
VroAM7_25090	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VroAM7_25110	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VroAM7_25140	COG1560	Kdo2-lipid A biosynthetic process
VroAM7_25150	COG0842	Transport permease protein
VroAM7_25160	COG1131	(ABC) transporter
VroAM7_25170	COG0659	secondary active sulfate transmembrane transporter activity
VroAM7_25180	COG0288	reversible hydration of carbon dioxide
VroAM7_25210	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VroAM7_25220	COG0508	dehydrogenase complex catalyzes the overall conversion of
VroAM7_25230	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VroAM7_25240	COG2186	Transcriptional regulator
VroAM7_25280	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VroAM7_25290	COG1459	type II secretion system
VroAM7_25310	COG0237	dephospho-CoA kinase activity
VroAM7_25320	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
VroAM7_25330	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
VroAM7_25380	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VroAM7_25400	COG4137	Cytochrome C assembly protein
VroAM7_25410	COG4536	flavin adenine dinucleotide binding
VroAM7_25450	COG0612	Peptidase, M16
VroAM7_25460	COG1238	metal cluster binding
VroAM7_25480	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VroAM7_25490	COG5016	pyruvate
VroAM7_25490	COG0511	ligase activity, forming carbon-carbon bonds
VroAM7_25520	COG0527	aspartate kinase activity
VroAM7_25550	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VroAM7_25560	COG1546	Belongs to the CinA family
VroAM7_25580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VroAM7_25590	COG1388	LysM domain
VroAM7_25590	COG4942	peptidase
VroAM7_25640	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VroAM7_25660	COG0148	phosphopyruvate hydratase activity
VroAM7_25680	COG3956	TIGRFAM MazG family protein
VroAM7_25690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VroAM7_25730	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
VroAM7_25740	COG1381	Involved in DNA repair and RecF pathway recombination
VroAM7_25750	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VroAM7_25770	COG0681	Belongs to the peptidase S26 family
VroAM7_25790	COG3086	response to oxidative stress
VroAM7_25820	COG1595	DNA-templated transcription, initiation
VroAM7_25840	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VroAM7_25850	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
VroAM7_25890	COG1943	Transposase
VroAM7_25900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VroAM7_25910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VroAM7_25920	COG3079	Belongs to the UPF0149 family
VroAM7_25930	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
VroAM7_25940	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
VroAM7_25960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VroAM7_25980	COG0583	DNA-binding transcription factor activity
VroAM7_26010	COG0668	transmembrane transport
VroAM7_26020	COG0191	fructose-bisphosphate aldolase activity
VroAM7_26060	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VroAM7_26070	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VroAM7_26110	COG2356	endonuclease I
VroAM7_26120	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VroAM7_26130	COG0189	ligase activity
VroAM7_26140	COG1678	Uncharacterized ACR, COG1678
VroAM7_26150	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VroAM7_26180	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
VroAM7_26190	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
VroAM7_26200	COG0762	integral membrane protein
VroAM7_26230	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
VroAM7_26240	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VroAM7_26320	COG1012	belongs to the aldehyde dehydrogenase family
VroAM7_26340	COG1609	Transcriptional regulator
VroAM7_26360	COG1486	melibiose metabolic process
VroAM7_26370	COG1447	Phosphotransferase system cellobiose-specific component IIA
VroAM7_26390	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VroAM7_26400	COG1028	Short-chain dehydrogenase reductase Sdr
VroAM7_26420	COG0795	lipopolysaccharide-transporting ATPase activity
VroAM7_26430	COG0795	lipopolysaccharide-transporting ATPase activity
VroAM7_26450	COG2927	DNA polymerase III (CHI subunit)
VroAM7_26460	COG0525	valine-tRNA ligase activity
VroAM7_26480	COG0456	acetyltransferase
VroAM7_26550	COG0251	oxidation-reduction process
VroAM7_26560	COG0204	Acyl-transferase
VroAM7_26580	COG5007	Belongs to the BolA IbaG family
VroAM7_26600	COG2854	intermembrane phospholipid transfer
VroAM7_26610	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VroAM7_26620	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VroAM7_26630	COG1127	ABC transporter
VroAM7_26650	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
VroAM7_26650	COG0517	IMP dehydrogenase activity
VroAM7_26670	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VroAM7_26680	COG1137	ATPase activity
VroAM7_26700	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VroAM7_26710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VroAM7_26730	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VroAM7_26740	COG2239	Acts as a magnesium transporter
VroAM7_26750	COG0312	modulator of DNA gyrase
VroAM7_26770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VroAM7_26780	COG0564	pseudouridine synthase activity
VroAM7_26810	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
VroAM7_26820	COG0312	modulator of DNA gyrase
VroAM7_26830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VroAM7_26840	COG3164	Protein of unknown function
VroAM7_26850	COG1530	ribonuclease E activity
VroAM7_26860	COG0424	maF-like protein
VroAM7_26870	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
VroAM7_26880	COG1792	Involved in formation and maintenance of cell shape
VroAM7_26890	COG1077	Cell shape determining protein MreB Mrl
VroAM7_26960	COG4969	Belongs to the N-Me-Phe pilin family
VroAM7_26980	COG1459	type II secretion system
VroAM7_26990	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VroAM7_27010	COG3409	Peptidoglycan-binding domain 1 protein
VroAM7_27010	COG3267	Type II secretory pathway component ExeA
VroAM7_27060	COG2199	diguanylate cyclase activity
VroAM7_27060	COG2200	EAL domain
VroAM7_27070	COG0629	single-stranded DNA binding
VroAM7_27100	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VroAM7_27120	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VroAM7_27130	COG0527	aspartate kinase activity
VroAM7_27140	COG0646	methionine synthase
VroAM7_27140	COG1410	methionine synthase
VroAM7_27190	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VroAM7_27230	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VroAM7_27240	COG0735	belongs to the Fur family
VroAM7_27270	COG0432	Pfam Uncharacterised protein family UPF0047
VroAM7_27290	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VroAM7_27300	COG0305	Participates in initiation and elongation during chromosome replication
VroAM7_27320	COG1943	Transposase
VroAM7_27350	COG2965	DNA replication, synthesis of RNA primer
VroAM7_27370	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VroAM7_27380	COG0338	D12 class N6 adenine-specific DNA methyltransferase
VroAM7_27470	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
VroAM7_27490	COG0678	peroxiredoxin activity
VroAM7_27490	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VroAM7_27500	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VroAM7_27500	COG0165	Argininosuccinate lyase
VroAM7_27530	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
VroAM7_27550	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VroAM7_27570	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VroAM7_27580	COG0460	homoserine dehydrogenase
VroAM7_27580	COG0527	aspartate kinase activity
VroAM7_27590	COG0626	cystathionine gamma-synthase activity
VroAM7_27610	COG0281	malic enzyme
VroAM7_27640	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VroAM7_27670	COG2168	tRNA wobble position uridine thiolation
VroAM7_27680	COG2923	Belongs to the DsrF TusC family
VroAM7_27690	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
VroAM7_27700	COG2964	Protein conserved in bacteria
VroAM7_27710	COG0545	Peptidyl-prolyl cis-trans isomerase
VroAM7_27740	COG1446	asparaginase
VroAM7_27750	COG1047	Peptidyl-prolyl cis-trans
VroAM7_27780	COG2249	NAD(P)H dehydrogenase (quinone) activity
VroAM7_27790	COG0488	(ABC) transporter
VroAM7_27810	COG0429	hydrolase of the alpha beta-hydrolase fold
VroAM7_27820	COG3089	Belongs to the UPF0270 family
VroAM7_27830	COG3954	Phosphoribulokinase
VroAM7_27840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VroAM7_27880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VroAM7_27900	COG0512	Glutamine amidotransferase of anthranilate synthase
VroAM7_27930	COG0546	phosphoglycolate phosphatase activity
VroAM7_27940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VroAM7_27950	COG0557	exoribonuclease II activity
VroAM7_27970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VroAM7_27970	COG1017	nitric oxide dioxygenase activity
VroAM7_27980	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
VroAM7_27990	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VroAM7_28000	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
VroAM7_28010	COG0330	HflC and HflK could
VroAM7_28020	COG0330	HflC and HflK could
VroAM7_28030	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VroAM7_28060	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
VroAM7_28070	COG0860	N-Acetylmuramoyl-L-alanine amidase
VroAM7_28080	COG0802	atpase or kinase
VroAM7_28090	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VroAM7_28110	COG1162	GTPase activity
VroAM7_28130	COG0471	metal ion transport
VroAM7_28160	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
VroAM7_28170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VroAM7_28200	COG1045	serine acetyltransferase
VroAM7_28210	COG4942	peptidase
VroAM7_28250	COG1053	succinate dehydrogenase
VroAM7_28260	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VroAM7_28320	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VroAM7_28330	COG1509	lysine 2,3-aminomutase activity
VroAM7_28340	COG1285	pathogenesis
VroAM7_28370	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VroAM7_28380	COG0534	Mate efflux family protein
VroAM7_28400	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
VroAM7_28410	COG3678	ATP-independent chaperone mediated protein folding
VroAM7_28420	COG0745	RESPONSE REGULATOR receiver
VroAM7_28430	COG2205	protein histidine kinase activity
VroAM7_28450	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
VroAM7_28460	COG3030	protein affecting phage T7 exclusion by the F plasmid
VroAM7_28470	COG1027	Aspartate ammonia-lyase
VroAM7_28480	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VroAM7_28490	COG4232	protein-disulfide reductase activity
VroAM7_28510	COG2095	MarC family integral membrane protein
VroAM7_28530	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VroAM7_28570	COG0784	Response regulator, receiver
VroAM7_28570	COG2205	protein histidine kinase activity
VroAM7_28570	COG2198	Histidine kinase
VroAM7_28580	COG2814	Major facilitator Superfamily
VroAM7_28610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VroAM7_28620	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VroAM7_28630	COG0511	ligase activity, forming carbon-carbon bonds
VroAM7_28640	COG0439	Biotin carboxylase
VroAM7_28660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VroAM7_28670	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VroAM7_28680	COG3300	MHYT domain
VroAM7_28680	COG5001	Diguanylate cyclase
VroAM7_28700	COG1982	Orn Lys Arg decarboxylase major
VroAM7_28710	COG0531	amino acid
VroAM7_28720	COG3710	Transcriptional regulator
VroAM7_28730	COG0789	Transcriptional regulator
VroAM7_28760	COG0151	Belongs to the GarS family
VroAM7_28790	COG1253	flavin adenine dinucleotide binding
VroAM7_28800	COG3068	Protein conserved in bacteria
VroAM7_28820	COG1573	uracil-dna glycosylase
VroAM7_28840	COG2816	NAD+ diphosphatase activity
VroAM7_28850	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
VroAM7_28890	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
VroAM7_28920	COG0250	Participates in transcription elongation, termination and antitermination
VroAM7_28930	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VroAM7_28970	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VroAM7_28990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VroAM7_29070	COG1309	transcriptional regulator
VroAM7_29080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VroAM7_29090	COG0534	Mate efflux family protein
VroAM7_29120	COG2937	Belongs to the GPAT DAPAT family
VroAM7_29140	COG3161	chorismate lyase activity
VroAM7_29150	COG1580	Controls the rotational direction of flagella during chemotaxis
VroAM7_29160	COG0705	Rhomboid family
VroAM7_29170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VroAM7_29190	COG2177	Part of the ABC transporter FtsEX involved in
VroAM7_29200	COG2884	Cell division ATP-binding protein ftsE
VroAM7_29210	COG0552	protein localization to endoplasmic reticulum
VroAM7_29210	COG0552	protein localization to endoplasmic reticulum
VroAM7_29220	COG0742	ribosomal rna small subunit methyltransferase
VroAM7_29240	COG2095	MarC family integral membrane protein
VroAM7_29330	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VroAM7_29340	COG0640	Transcriptional regulator
VroAM7_29350	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VroAM7_29360	COG1280	lysine exporter protein (LysE YggA)
VroAM7_29370	COG2267	carboxylic ester hydrolase activity
VroAM7_29380	COG0561	phosphatase activity
VroAM7_29420	COG3287	FIST C domain
VroAM7_29420	COG2199	diguanylate cyclase activity
VroAM7_29420	COG2200	EAL domain
VroAM7_29430	COG1011	Hydrolase
VroAM7_29470	COG0019	diaminopimelate decarboxylase activity
VroAM7_29490	COG3072	Adenylate cyclase
VroAM7_29510	COG1587	Uroporphyrinogen-III synthase
VroAM7_29520	COG2959	enzyme of heme biosynthesis
VroAM7_29530	COG3071	HemY protein
VroAM7_29540	COG1943	Transposase
VroAM7_29560	COG0633	Ferredoxin
VroAM7_29570	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
VroAM7_29590	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
VroAM7_29600	COG3118	belongs to the thioredoxin family
VroAM7_29630	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
VroAM7_29650	COG0514	ATP-dependent DNA helicase (RecQ)
VroAM7_29660	COG2962	Rard protein
VroAM7_29690	COG1280	lysine exporter protein (LysE YggA)
VroAM7_29700	COG0405	Gamma-glutamyltransferase
VroAM7_29710	COG0210	DNA helicase
VroAM7_29730	COG3220	belongs to the UPF0276 family
VroAM7_29770	COG2814	Major facilitator Superfamily
VroAM7_29790	COG0006	proline dipeptidase activity
VroAM7_29790	COG0006	proline dipeptidase activity
VroAM7_29820	COG2104	thiamine diphosphate biosynthetic process
VroAM7_29830	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VroAM7_29870	COG2132	Multicopper oxidase
VroAM7_29880	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
VroAM7_29930	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VroAM7_29940	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
VroAM7_29950	COG0551	DNA topoisomerase type I activity
VroAM7_29970	COG0758	DNA mediated transformation
VroAM7_30010	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VroAM7_30010	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VroAM7_30020	COG0569	domain protein
VroAM7_30030	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VroAM7_30050	COG1272	protein, Hemolysin III
VroAM7_30060	COG4326	sporulation control protein
VroAM7_30080	COG3084	Protein conserved in bacteria
VroAM7_30100	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VroAM7_30110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VroAM7_30120	COG0204	Acyl-transferase
VroAM7_30140	COG0606	chelatase, subunit chli
VroAM7_30210	COG0606	chelatase, subunit chli
VroAM7_30320	COG3978	acetolactate synthase activity
VroAM7_30330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VroAM7_30340	COG0129	dihydroxy-acid dehydratase activity
VroAM7_30360	COG0583	DNA-binding transcription factor activity
VroAM7_30370	COG2814	Major facilitator Superfamily
VroAM7_30380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VroAM7_30390	COG0765	amino acid transport
VroAM7_30410	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VroAM7_30430	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VroAM7_30490	COG3312	ion transport
VroAM7_30500	COG1475	DNA binding
VroAM7_30510	COG1192	Involved in chromosome partitioning
VroAM7_30540	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VroAM7_30590	COG1126	abc transporter atp-binding protein
VroAM7_30610	COG1943	Transposase
VroAM7_30700	COG1051	belongs to the nudix hydrolase family
VroAM7_30710	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VroAM7_30720	COG5001	Diguanylate cyclase
VroAM7_30740	COG1129	ABC transporter
VroAM7_30750	COG1172	Belongs to the binding-protein-dependent transport system permease family
VroAM7_30760	COG1879	ABC-type sugar transport system periplasmic component
VroAM7_30770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VroAM7_30780	COG1609	Transcriptional regulator
VroAM7_30790	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VroAM7_30820	COG4607	ABC-type enterochelin transport system periplasmic component
VroAM7_30830	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VroAM7_30840	COG4605	iron ion homeostasis
VroAM7_30850	COG4604	ABC transporter, ATP-binding protein
VroAM7_30860	COG0789	Transcriptional regulator
VroAM7_30880	COG4206	TonB-dependent receptor
VroAM7_30920	COG2962	Rard protein
VroAM7_30950	COG0671	phosphoesterase, PA-phosphatase related
VroAM7_30980	COG2076	Multidrug Resistance protein
VroAM7_31050	COG2067	long-chain fatty acid transport protein
VroAM7_31060	COG1234	tRNA 3'-trailer cleavage
VroAM7_31080	COG0069	glutamate synthase activity
VroAM7_31080	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
VroAM7_31110	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
VroAM7_31110	COG2755	lipolytic protein G-D-S-L family
VroAM7_31130	COG1902	pentaerythritol trinitrate reductase activity
VroAM7_31140	COG0346	lactoylglutathione lyase activity
VroAM7_31180	COG0739	heme binding
VroAM7_31210	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
VroAM7_31250	COG0628	permease
VroAM7_31290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VroAM7_31300	COG1999	signal sequence binding
VroAM7_31330	COG3005	denitrification pathway
VroAM7_31360	COG0583	DNA-binding transcription factor activity
VroAM7_31380	COG3706	GGDEF domain
VroAM7_31380	COG0745	RESPONSE REGULATOR receiver
VroAM7_31630	COG2816	NAD+ diphosphatase activity
VroAM7_31640	COG1132	(ABC) transporter
VroAM7_31660	COG0583	DNA-binding transcription factor activity
VroAM7_31670	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VroAM7_31710	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VroAM7_31720	COG0583	DNA-binding transcription factor activity
VroAM7_31760	COG0509	glycine decarboxylation via glycine cleavage system
VroAM7_31770	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VroAM7_31790	COG0404	The glycine cleavage system catalyzes the degradation of glycine
VroAM7_31810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VroAM7_31820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VroAM7_31850	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VroAM7_31850	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
VroAM7_31850	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VroAM7_31860	COG1105	Belongs to the carbohydrate kinase PfkB family
VroAM7_31870	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VroAM7_31870	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VroAM7_31880	COG1609	Transcriptional regulator
VroAM7_31930	COG0765	amino acid transport
VroAM7_31940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VroAM7_31950	COG0765	amino acid transport
VroAM7_31960	COG1126	abc transporter atp-binding protein
VroAM7_31980	COG1979	alcohol dehydrogenase
VroAM7_31990	COG2207	Transcriptional regulator
VroAM7_32010	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VroAM7_32030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VroAM7_32060	COG3437	response regulator, receiver
VroAM7_32060	COG0784	Response regulator, receiver
VroAM7_32070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VroAM7_32080	COG0840	transmembrane signaling receptor activity
VroAM7_32100	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
VroAM7_32110	COG0513	Belongs to the DEAD box helicase family
VroAM7_32120	COG4943	cyclic-guanylate-specific phosphodiesterase activity
VroAM7_32150	COG3038	cytochrome b561
VroAM7_32170	COG2116	formate transmembrane transporter activity
VroAM7_32180	COG0583	DNA-binding transcription factor activity
VroAM7_32200	COG3593	DNA synthesis involved in DNA repair
VroAM7_32210	COG0737	Belongs to the 5'-nucleotidase family
VroAM7_32240	COG0646	methionine synthase
VroAM7_32240	COG1410	methionine synthase
VroAM7_32270	COG2267	carboxylic ester hydrolase activity
VroAM7_32280	COG2067	long-chain fatty acid transport protein
VroAM7_32320	COG2050	protein possibly involved in aromatic compounds catabolism
VroAM7_32390	COG0484	heat shock protein binding
VroAM7_32410	COG5001	Diguanylate cyclase
VroAM7_32410	COG3300	MHYT domain
VroAM7_32420	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VroAM7_32440	COG4181	ATPase activity
VroAM7_32450	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
VroAM7_32470	COG1984	allophanate hydrolase subunit 2
VroAM7_32480	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
VroAM7_32500	COG5002	protein histidine kinase activity
VroAM7_32500	COG5001	Diguanylate cyclase
VroAM7_32500	COG3447	MASE1 domain protein
VroAM7_32510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VroAM7_32530	COG0583	DNA-binding transcription factor activity
VroAM7_32540	COG0045	succinate-CoA ligase (ADP-forming) activity
VroAM7_32540	COG1042	CoA-binding domain protein
VroAM7_32540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VroAM7_32550	COG3266	domain, Protein
VroAM7_32580	COG0023	Translation Initiation Factor
VroAM7_32640	COG3140	Belongs to the UPF0181 family
VroAM7_32670	COG0745	RESPONSE REGULATOR receiver
VroAM7_32690	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
VroAM7_32700	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
VroAM7_32730	COG3706	GGDEF domain
VroAM7_32730	COG0745	RESPONSE REGULATOR receiver
VroAM7_32760	COG5001	Diguanylate cyclase
VroAM7_32760	COG4251	negative regulation of phosphorylation
VroAM7_32760	COG3706	GGDEF domain
VroAM7_32760	COG2203	Gaf domain
VroAM7_32770	COG0745	RESPONSE REGULATOR receiver
VroAM7_32790	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
VroAM7_32800	COG4149	molybdate abc transporter
VroAM7_32810	COG0725	ABC transporter, periplasmic molybdate-binding protein
VroAM7_32830	COG3111	PFAM Bacterial OB fold (BOF) protein
VroAM7_32850	COG0189	ligase activity
VroAM7_32850	COG4067	protein conserved in archaea
VroAM7_32880	COG0534	Mate efflux family protein
VroAM7_32900	COG0602	queuosine metabolic process
VroAM7_32910	COG1328	CTP reductase activity
VroAM7_33010	COG2199	diguanylate cyclase activity
VroAM7_33030	COG0745	RESPONSE REGULATOR receiver
VroAM7_33030	COG3706	GGDEF domain
VroAM7_33040	COG0840	transmembrane signaling receptor activity
VroAM7_33080	COG2199	diguanylate cyclase activity
VroAM7_33080	COG2203	Gaf domain
VroAM7_33100	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VroAM7_33110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
VroAM7_33220	COG1570	exodeoxyribonuclease VII activity
VroAM7_33270	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
VroAM7_33290	COG1403	HNH endonuclease
VroAM7_33350	COG0210	DNA helicase
VroAM7_33430	COG0446	pyridine nucleotide-disulphide oxidoreductase
VroAM7_33500	COG2197	response regulator
VroAM7_33510	COG3851	Histidine kinase
VroAM7_33520	COG2271	Major facilitator Superfamily
VroAM7_33530	COG1482	cell wall glycoprotein biosynthetic process
VroAM7_33550	COG0628	permease
VroAM7_33570	COG1566	PFAM secretion protein HlyD family protein
VroAM7_33620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VroAM7_33630	COG3118	belongs to the thioredoxin family
VroAM7_33640	COG2814	Major facilitator Superfamily
VroAM7_33660	COG2205	protein histidine kinase activity
VroAM7_33660	COG0784	Response regulator, receiver
VroAM7_33680	COG2199	diguanylate cyclase activity
VroAM7_33680	COG2202	Pas domain
VroAM7_33680	COG2200	EAL domain
VroAM7_33750	COG0840	transmembrane signaling receptor activity
VroAM7_33760	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VroAM7_33800	COG2116	formate transmembrane transporter activity
VroAM7_33810	COG2146	nitrite reductase [NAD(P)H] activity
VroAM7_33820	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VroAM7_33890	COG0840	transmembrane signaling receptor activity
VroAM7_33930	COG0277	FAD linked oxidase domain protein
VroAM7_33940	COG0583	DNA-binding transcription factor activity
VroAM7_33950	COG2425	protein containing a von Willebrand factor type A (vWA) domain
VroAM7_33980	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
VroAM7_34000	COG1288	antiporter activity
VroAM7_34020	COG2814	Major facilitator Superfamily
VroAM7_34040	COG3040	lipid binding
VroAM7_34100	COG0419	ATPase involved in DNA repair
VroAM7_34110	COG0420	3'-5' exonuclease activity
VroAM7_34140	COG3501	Rhs element vgr protein
VroAM7_34250	COG0631	protein serine/threonine phosphatase activity
VroAM7_34320	COG0515	serine threonine protein kinase
VroAM7_34320	COG2815	serine threonine protein kinase
VroAM7_34370	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
VroAM7_34380	COG2801	Transposase and inactivated derivatives
VroAM7_34450	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VroAM7_34450	COG2146	nitrite reductase [NAD(P)H] activity
VroAM7_34460	COG1116	anion transmembrane transporter activity
VroAM7_34470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
VroAM7_34480	COG1116	anion transmembrane transporter activity
VroAM7_34480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
VroAM7_34500	COG3707	response regulator
VroAM7_34540	COG0243	molybdopterin cofactor binding
VroAM7_34560	COG5002	protein histidine kinase activity
VroAM7_34560	COG5001	Diguanylate cyclase
VroAM7_34570	COG0814	amino acid
VroAM7_34590	COG3706	GGDEF domain
VroAM7_34640	COG1785	Belongs to the alkaline phosphatase family
VroAM7_34660	COG0210	DNA helicase
VroAM7_34670	COG1289	transmembrane transporter activity
VroAM7_34710	COG0784	Response regulator, receiver
VroAM7_34710	COG0835	chemotaxis
VroAM7_34720	COG0778	Nitroreductase
VroAM7_34730	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
VroAM7_34780	COG3069	C4-dicarboxylate transmembrane transporter activity
VroAM7_34790	COG1704	LemA family
VroAM7_34800	COG0501	Belongs to the peptidase M48B family
VroAM7_34850	COG0641	radical SAM
VroAM7_34890	COG3111	PFAM Bacterial OB fold (BOF) protein
VroAM7_34900	COG1597	lipid kinase activity
VroAM7_34910	COG0583	DNA-binding transcription factor activity
VroAM7_34920	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VroAM7_34920	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VroAM7_34980	COG0714	Associated with various cellular activities
VroAM7_34990	COG0641	radical SAM
VroAM7_35000	COG3119	arylsulfatase activity
VroAM7_35010	COG0583	DNA-binding transcription factor activity
VroAM7_35030	COG3119	arylsulfatase activity
VroAM7_35040	COG3119	arylsulfatase activity
VroAM7_35080	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VroAM7_35080	COG0515	serine threonine protein kinase
VroAM7_35120	COG2205	protein histidine kinase activity
VroAM7_35120	COG2198	Histidine kinase
VroAM7_35120	COG0784	Response regulator, receiver
VroAM7_35130	COG1879	ABC-type sugar transport system periplasmic component
VroAM7_35150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VroAM7_35160	COG0840	transmembrane signaling receptor activity
VroAM7_35200	COG2195	Cleaves the N-terminal amino acid of tripeptides
VroAM7_35230	COG4989	oxidoreductase activity
VroAM7_35280	COG1914	H( )-stimulated, divalent metal cation uptake system
VroAM7_35320	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VroAM7_35350	COG2897	thiosulfate sulfurtransferase activity
VroAM7_35390	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
VroAM7_35400	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VroAM7_35410	COG0840	transmembrane signaling receptor activity
VroAM7_35420	COG2814	Major facilitator Superfamily
VroAM7_35430	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VroAM7_35460	COG1612	heme a metabolic process
VroAM7_35510	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
VroAM7_35540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VroAM7_35560	COG1280	lysine exporter protein (LysE YggA)
VroAM7_35600	COG0179	Fumarylacetoacetate (FAA) hydrolase
VroAM7_35620	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VroAM7_35630	COG0697	spore germination
VroAM7_35670	COG2814	Major facilitator Superfamily
VroAM7_35680	COG0583	DNA-binding transcription factor activity
VroAM7_35690	COG5001	Diguanylate cyclase
VroAM7_35700	COG0739	heme binding
VroAM7_35760	COG0814	amino acid
VroAM7_35770	COG0840	transmembrane signaling receptor activity
VroAM7_35780	COG0366	Alpha amylase catalytic
VroAM7_35790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VroAM7_35800	COG0835	chemotaxis
VroAM7_35800	COG0784	Response regulator, receiver
VroAM7_35820	COG0748	coenzyme F420 binding
VroAM7_35830	COG3721	Heme iron utilization protein
VroAM7_35850	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VroAM7_35860	COG0811	peptide transport
VroAM7_35870	COG0848	biopolymer transport protein
VroAM7_35890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VroAM7_35900	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
VroAM7_35980	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
VroAM7_36000	COG3217	Mosc domain protein beta barrel domain protein
VroAM7_36000	COG0633	Ferredoxin
VroAM7_36000	COG0633	Ferredoxin
VroAM7_36000	COG3217	Mosc domain protein beta barrel domain protein
VroAM7_36010	COG0401	homolog of Blt101
VroAM7_36030	COG2354	Protein conserved in bacteria
VroAM7_36090	COG3833	ABC-type maltose transport systems, permease component
VroAM7_36100	COG1175	transmembrane transport
VroAM7_36120	COG3842	ATPase activity
VroAM7_36130	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VroAM7_36170	COG0438	transferase activity, transferring glycosyl groups
VroAM7_36230	COG1309	transcriptional regulator
VroAM7_36240	COG2130	NADP-dependent
VroAM7_36260	COG0753	catalase activity
VroAM7_36270	COG2084	Dehydrogenase
VroAM7_36290	COG0583	DNA-binding transcription factor activity
VroAM7_36300	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VroAM7_36310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VroAM7_36330	COG2207	Transcriptional regulator
VroAM7_36340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VroAM7_36340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VroAM7_36340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VroAM7_36410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VroAM7_36450	COG1131	(ABC) transporter
VroAM7_36460	COG0842	Transport permease protein
VroAM7_36500	COG3383	formate dehydrogenase (NAD+) activity
VroAM7_36540	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VroAM7_36610	COG0456	acetyltransferase
VroAM7_36640	COG0494	nUDIX hydrolase
VroAM7_36670	COG1858	cytochrome C peroxidase
VroAM7_36690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VroAM7_36700	COG1505	serine-type exopeptidase activity
VroAM7_36710	COG0488	(ABC) transporter
VroAM7_36720	COG1720	tRNA m6t6A37 methyltransferase activity
VroAM7_36760	COG2814	Major facilitator Superfamily
VroAM7_36790	COG0583	DNA-binding transcription factor activity
VroAM7_36800	COG0589	response to stress
VroAM7_36860	COG1846	Transcriptional regulator
VroAM7_36880	COG0523	cobalamin synthesis protein
VroAM7_36890	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
VroAM7_36900	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
VroAM7_36920	COG4667	esterase of the alpha-beta hydrolase superfamily
VroAM7_36930	COG1741	Belongs to the pirin family
VroAM7_36940	COG1278	Cold shock
VroAM7_36970	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VroAM7_37040	COG2226	methyltransferase
VroAM7_37060	COG3706	GGDEF domain
VroAM7_37070	COG1686	Belongs to the peptidase S11 family
VroAM7_37080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VroAM7_37090	COG2249	NAD(P)H dehydrogenase (quinone) activity
VroAM7_37100	COG0583	DNA-binding transcription factor activity
VroAM7_37110	COG0625	glutathione transferase activity
VroAM7_37130	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
VroAM7_37140	COG1621	beta-fructofuranosidase activity
VroAM7_37150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VroAM7_37160	COG1263	PTS System
VroAM7_37160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VroAM7_37200	COG4771	TonB-dependent receptor
VroAM7_37210	COG0583	DNA-binding transcription factor activity
VroAM7_37220	COG1028	Short-chain dehydrogenase reductase Sdr
VroAM7_37270	COG3746	phosphate-selective porin O and P
VroAM7_37310	COG1028	Short-chain dehydrogenase reductase Sdr
VroAM7_37330	COG0583	DNA-binding transcription factor activity
VroAM7_37340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VroAM7_37340	COG2207	Transcriptional regulator
VroAM7_37350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VroAM7_37410	COG0513	Belongs to the DEAD box helicase family
VroAM7_37430	COG0583	DNA-binding transcription factor activity
VroAM7_37470	COG1028	Short-chain dehydrogenase reductase Sdr
VroAM7_37480	COG2814	Major facilitator Superfamily
VroAM7_37500	COG1902	pentaerythritol trinitrate reductase activity
VroAM7_37530	COG3122	Protein conserved in bacteria
VroAM7_37560	COG0583	DNA-binding transcription factor activity
VroAM7_37600	COG0574	Belongs to the PEP-utilizing enzyme family
VroAM7_37600	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
VroAM7_37620	COG2197	response regulator
VroAM7_37630	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VroAM7_37660	COG0583	DNA-binding transcription factor activity
VroAM7_37670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VroAM7_37690	COG1538	Outer membrane efflux protein
VroAM7_37700	COG0786	glutamate:sodium symporter activity
VroAM7_37750	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VroAM7_37760	COG0318	PFAM AMP-dependent synthetase and ligase
VroAM7_37840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VroAM7_37880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VroAM7_37980	COG4948	Mandelate Racemase Muconate Lactonizing
VroAM7_37990	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VroAM7_38010	COG0348	domain, Protein
VroAM7_38020	COG0437	4 iron, 4 sulfur cluster binding
VroAM7_38030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VroAM7_38070	COG0840	transmembrane signaling receptor activity
VroAM7_38080	COG0840	transmembrane signaling receptor activity
VroAM7_38090	COG1067	ATP-dependent peptidase activity
VroAM7_38110	COG4172	Belongs to the ABC transporter superfamily
VroAM7_38120	COG1505	serine-type exopeptidase activity
VroAM7_38130	COG0583	DNA-binding transcription factor activity
VroAM7_38140	COG1620	l-lactate permease
VroAM7_38150	COG1304	FMN binding
VroAM7_38180	COG0668	transmembrane transport
VroAM7_38260	COG1342	Belongs to the UPF0251 family
VroAM7_38280	COG4176	ABC-type proline glycine betaine transport system permease component
VroAM7_38290	COG3448	diguanylate cyclase activity
VroAM7_38290	COG4175	Glycine betaine
VroAM7_38320	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VroAM7_38330	COG0589	response to stress
VroAM7_38340	COG0583	DNA-binding transcription factor activity
VroAM7_38450	COG1335	isochorismatase
VroAM7_38490	COG1349	DNA-binding transcription factor activity
VroAM7_38500	COG0346	lactoylglutathione lyase activity
VroAM7_38510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VroAM7_38510	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VroAM7_38540	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VroAM7_38550	COG2070	2-Nitropropane dioxygenase
VroAM7_38560	COG0531	amino acid
VroAM7_38570	COG4302	ethanolamine ammonia-lyase activity
VroAM7_38590	COG4771	TonB-dependent receptor
VroAM7_38600	COG2382	esterase
VroAM7_38610	COG2207	Transcriptional regulator
VroAM7_38640	COG1280	lysine exporter protein (LysE YggA)
VroAM7_38650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VroAM7_38680	COG3226	Transcriptional regulator
VroAM7_38710	COG0583	DNA-binding transcription factor activity
VroAM7_38750	COG0435	Glutathione S-transferase
VroAM7_38760	COG0431	NADPH-dependent FMN reductase
VroAM7_38770	COG0583	DNA-binding transcription factor activity
VroAM7_38780	COG4628	conserved protein (DUF2132)
VroAM7_38790	COG0488	(ABC) transporter
VroAM7_38800	COG0346	lactoylglutathione lyase activity
VroAM7_38810	COG0384	phenazine biosynthesis protein PhzF
VroAM7_38820	COG0251	oxidation-reduction process
VroAM7_38870	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VroAM7_38880	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
VroAM7_38890	COG2199	diguanylate cyclase activity
VroAM7_38920	COG0454	-acetyltransferase
VroAM7_38940	COG2814	Major facilitator Superfamily
VroAM7_39030	COG0628	permease
VroAM7_39040	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VroAM7_39050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VroAM7_39070	COG3033	Beta-eliminating lyase
VroAM7_39110	COG0579	oxidoreductase
VroAM7_39150	COG1114	Component of the transport system for branched-chain amino acids
VroAM7_39170	COG4191	Histidine kinase
VroAM7_39250	COG0583	DNA-binding transcription factor activity
VroAM7_39290	COG0189	ligase activity
VroAM7_39300	COG0189	ligase activity
VroAM7_39300	COG4067	protein conserved in archaea
VroAM7_39320	COG1166	arginine decarboxylase activity
VroAM7_39330	COG0010	Belongs to the arginase family
VroAM7_39340	COG2814	Major facilitator Superfamily
VroAM7_39350	COG1770	oligopeptidase
VroAM7_39380	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VroAM7_39390	COG1121	(ABC) transporter
VroAM7_39400	COG0803	Belongs to the bacterial solute-binding protein 9 family
VroAM7_39490	COG0848	biopolymer transport protein
VroAM7_39500	COG0811	peptide transport
VroAM7_39510	COG0811	peptide transport
VroAM7_39560	COG0745	RESPONSE REGULATOR receiver
VroAM7_39580	COG0584	glycerophosphoryl diester phosphodiesterase
VroAM7_39600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VroAM7_39640	COG0312	modulator of DNA gyrase
VroAM7_39650	COG0312	modulator of DNA gyrase
VroAM7_39660	COG0351	phosphomethylpyrimidine kinase
VroAM7_39670	COG1116	anion transmembrane transporter activity
VroAM7_39680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
VroAM7_39690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
VroAM7_39700	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
VroAM7_39730	COG0671	phosphoesterase, PA-phosphatase related
VroAM7_39750	COG1028	Short-chain dehydrogenase reductase Sdr
VroAM7_39790	COG0456	acetyltransferase
VroAM7_39800	COG3157	Type VI secretion system effector, Hcp
VroAM7_39880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VroAM7_39890	COG1929	Belongs to the glycerate kinase type-1 family
VroAM7_39960	COG0546	phosphoglycolate phosphatase activity
VroAM7_40070	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
VroAM7_40070	COG3408	Glycogen debranching enzyme
VroAM7_40100	COG2814	Major facilitator Superfamily
VroAM7_40140	COG3047	cAMP biosynthetic process
VroAM7_40150	COG1357	PFAM Pentapeptide repeats (8 copies)
VroAM7_40180	COG0534	Mate efflux family protein
VroAM7_40210	COG2076	Multidrug Resistance protein
VroAM7_40280	COG0583	DNA-binding transcription factor activity
VroAM7_40300	COG0583	DNA-binding transcription factor activity
VroAM7_40320	COG2162	N-hydroxyarylamine O-acetyltransferase activity
VroAM7_40330	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
VroAM7_40360	COG3152	Membrane
VroAM7_40400	COG0561	phosphatase activity
VroAM7_40410	COG0564	pseudouridine synthase activity
VroAM7_40420	COG1522	sequence-specific DNA binding
VroAM7_40450	COG0406	alpha-ribazole phosphatase activity
VroAM7_40540	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VroAM7_40600	COG0534	Mate efflux family protein
VroAM7_40610	COG1472	Belongs to the glycosyl hydrolase 3 family
VroAM7_40660	COG1609	Transcriptional regulator
VroAM7_40680	COG4608	Belongs to the ABC transporter superfamily
VroAM7_40690	COG0444	Belongs to the ABC transporter superfamily
VroAM7_40700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VroAM7_40720	COG0747	negative chemotaxis
VroAM7_40740	COG1609	Transcriptional regulator
VroAM7_40750	COG3842	ATPase activity
VroAM7_40760	COG2723	6-phospho-beta-galactosidase activity
VroAM7_40770	COG0395	ABC-type sugar transport system, permease component
VroAM7_40800	COG1609	Transcriptional regulator
VroAM7_40820	COG5001	Diguanylate cyclase
VroAM7_40840	COG3123	guanosine phosphorylase activity
VroAM7_40930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
VroAM7_40950	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
VroAM7_40960	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
VroAM7_41050	COG0786	glutamate:sodium symporter activity
VroAM7_41060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VroAM7_41070	COG1131	(ABC) transporter
VroAM7_41100	COG0786	glutamate:sodium symporter activity
VroAM7_41170	COG1028	Short-chain dehydrogenase reductase Sdr
VroAM7_41230	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VroAM7_41250	COG3279	Response regulator of the LytR AlgR family
VroAM7_41260	COG3275	phosphorelay sensor kinase activity
VroAM7_41320	COG0583	DNA-binding transcription factor activity
VroAM7_41330	COG1566	PFAM secretion protein HlyD family protein
VroAM7_41350	COG0772	Belongs to the SEDS family
VroAM7_41400	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VroAM7_41400	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
VroAM7_41420	COG0444	Belongs to the ABC transporter superfamily
VroAM7_41430	COG4608	Belongs to the ABC transporter superfamily
VroAM7_41480	COG1444	tRNA N-acetyltransferase activity
VroAM7_41600	COG2204	response regulator
VroAM7_41620	COG0259	pyridoxamine-phosphate oxidase activity
VroAM7_41630	COG1132	(ABC) transporter
VroAM7_41650	COG1312	Catalyzes the dehydration of D-mannonate
VroAM7_41660	COG3655	Transcriptional regulator
VroAM7_41690	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
VroAM7_41710	COG1595	DNA-templated transcription, initiation
VroAM7_41730	COG0667	Aldo Keto reductase
VroAM7_41740	COG0513	Belongs to the DEAD box helicase family
VroAM7_41750	COG3713	MltA-interacting MipA family protein
VroAM7_41770	COG2258	MOSC domain
VroAM7_41800	COG1522	sequence-specific DNA binding
VroAM7_41830	COG0840	transmembrane signaling receptor activity
VroAM7_41870	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
VroAM7_41880	COG0583	DNA-binding transcription factor activity
VroAM7_41900	COG3634	alkyl hydroperoxide reductase activity
VroAM7_41910	COG0450	alkyl hydroperoxide reductase
VroAM7_41920	COG1846	Transcriptional regulator
VroAM7_41930	COG1764	response to oxidative stress
VroAM7_42000	COG1136	(ABC) transporter
VroAM7_42020	COG1355	regulation of microtubule-based process
VroAM7_42080	COG4772	TonB-dependent receptor
VroAM7_42090	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
VroAM7_42100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VroAM7_42110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VroAM7_42120	COG1120	ATPase activity
VroAM7_42130	COG0840	transmembrane signaling receptor activity
VroAM7_42140	COG0612	Peptidase, M16
VroAM7_42170	COG0739	heme binding
VroAM7_42230	COG4604	ABC transporter, ATP-binding protein
VroAM7_42240	COG4605	iron ion homeostasis
VroAM7_42250	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VroAM7_42260	COG4607	ABC-type enterochelin transport system periplasmic component
VroAM7_42270	COG0583	DNA-binding transcription factor activity
VroAM7_42280	COG4771	TonB-dependent receptor
VroAM7_42300	COG3214	Protein conserved in bacteria
VroAM7_42310	COG2814	Major facilitator Superfamily
VroAM7_42340	COG2203	Gaf domain
VroAM7_42340	COG2199	diguanylate cyclase activity
VroAM7_42400	COG2356	endonuclease I
VroAM7_42450	COG1982	Orn Lys Arg decarboxylase major
VroAM7_42460	COG0531	amino acid
VroAM7_42490	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
VroAM7_42500	COG1162	GTPase activity
VroAM7_42530	COG1999	signal sequence binding
VroAM7_42570	COG0058	SHG alpha-glucan phosphorylase activity
VroAM7_42580	COG1640	4-alpha-glucanotransferase
VroAM7_42590	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
VroAM7_42600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VroAM7_42610	COG0366	Alpha amylase catalytic
VroAM7_42640	COG3366	ferrous iron transmembrane transporter activity
VroAM7_42650	COG0700	Nucleoside recognition
VroAM7_42660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VroAM7_42670	COG3339	Conserved Protein
VroAM7_42680	COG1301	dicarboxylic acid transport
VroAM7_42740	COG0583	DNA-binding transcription factor activity
VroAM7_42790	COG2095	MarC family integral membrane protein
VroAM7_42800	COG0840	transmembrane signaling receptor activity
VroAM7_42820	COG4667	esterase of the alpha-beta hydrolase superfamily
VroAM7_42840	COG0415	Belongs to the DNA photolyase family
VroAM7_42870	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VroAM7_42880	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VroAM7_42940	COG1686	Belongs to the peptidase S11 family
VroAM7_42980	COG0583	DNA-binding transcription factor activity
VroAM7_42990	COG4628	conserved protein (DUF2132)
VroAM7_43010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VroAM7_43050	COG3706	GGDEF domain
VroAM7_43090	COG3706	GGDEF domain
VroAM7_43100	COG0415	Belongs to the DNA photolyase family
VroAM7_43110	COG3046	protein related to deoxyribodipyrimidine photolyase
VroAM7_43130	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VroAM7_43130	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VroAM7_43140	COG1765	OsmC-like protein
VroAM7_43230	COG1011	Hydrolase
VroAM7_43290	COG1511	domain protein
VroAM7_43290	COG3264	Mechanosensitive ion channel
VroAM7_43310	COG3240	lipase activity
VroAM7_43370	COG1840	ABC-type Fe3 transport system, periplasmic component
VroAM7_43390	COG3842	ATPase activity
VroAM7_43440	COG2990	Protein conserved in bacteria
VroAM7_43460	COG2866	Carboxypeptidase
VroAM7_43530	COG1760	l-serine dehydratase
VroAM7_43580	COG1388	LysM domain
VroAM7_43580	COG0741	lytic transglycosylase activity
VroAM7_43620	COG1815	bacterial-type flagellum-dependent cell motility
VroAM7_43630	COG1558	bacterial-type flagellum-dependent cell motility
VroAM7_43640	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
VroAM7_43650	COG1749	Flagellar hook protein flgE
VroAM7_43660	COG4787	bacterial-type flagellum-dependent cell motility
VroAM7_43670	COG4786	Flagellar basal body rod
VroAM7_43680	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VroAM7_43690	COG1706	bacterial-type flagellum-dependent cell motility
VroAM7_43710	COG1256	bacterial-type flagellum assembly
VroAM7_43710	COG4786	Flagellar basal body rod
VroAM7_43850	COG1360	Flagellar Motor Protein
VroAM7_43860	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VroAM7_43870	COG1191	sigma factor activity
VroAM7_43880	COG1580	Controls the rotational direction of flagella during chemotaxis
VroAM7_43920	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VroAM7_43930	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VroAM7_43980	COG1987	bacterial-type flagellum assembly
VroAM7_44030	COG2204	response regulator
VroAM7_44060	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VroAM7_44100	COG2200	EAL domain
VroAM7_44200	COG0346	lactoylglutathione lyase activity
VroAM7_44250	COG0745	RESPONSE REGULATOR receiver
VroAM7_44270	COG0156	8-amino-7-oxononanoate synthase activity
VroAM7_44280	COG1063	alcohol dehydrogenase
VroAM7_44340	COG1122	ATPase activity
VroAM7_44360	COG1566	PFAM secretion protein HlyD family protein
VroAM7_44390	COG3706	GGDEF domain
VroAM7_44420	COG0813	purine-nucleoside phosphorylase activity
VroAM7_44430	COG3272	Protein of unknown function (DUF1722)
VroAM7_44440	COG0789	Transcriptional regulator
VroAM7_44450	COG0415	Belongs to the DNA photolyase family
VroAM7_44460	COG1388	LysM domain
VroAM7_44460	COG1376	ErfK ybiS ycfS ynhG family protein
VroAM7_44650	COG4695	Portal protein
VroAM7_44940	COG0513	Belongs to the DEAD box helicase family
VroAM7_44950	COG1770	oligopeptidase
VroAM7_44960	COG4771	TonB-dependent receptor
VroAM7_45030	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VroAM7_45040	COG0573	inorganic phosphate transmembrane transporter activity
VroAM7_45050	COG0581	inorganic phosphate transmembrane transporter activity
VroAM7_45090	COG2304	oxidoreductase activity
VroAM7_45130	COG0714	Associated with various cellular activities
VroAM7_45140	COG0840	transmembrane signaling receptor activity
VroAM7_45160	COG2197	response regulator
VroAM7_45200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VroAM7_45210	COG0110	maltose O-acetyltransferase activity
VroAM7_45220	COG1028	Short-chain dehydrogenase reductase Sdr
VroAM7_45250	COG2885	chlorophyll binding
VroAM7_45250	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
VroAM7_45260	COG5001	Diguanylate cyclase
VroAM7_45260	COG4251	negative regulation of phosphorylation
VroAM7_45260	COG2203	Gaf domain
VroAM7_45260	COG3706	GGDEF domain
VroAM7_45290	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VroAM7_45300	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
VroAM7_45320	COG1252	NADH dehydrogenase
VroAM7_45330	COG1301	dicarboxylic acid transport
VroAM7_45350	COG1881	PFAM PEBP family protein
VroAM7_45370	COG0798	PFAM Bile acid sodium symporter
VroAM7_45400	COG1733	regulation of RNA biosynthetic process
VroAM7_45450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VroAM7_45460	COG2213	PTS system mannitol-specific
VroAM7_45470	COG1063	alcohol dehydrogenase
VroAM7_45490	COG1072	(Pantothenic acid kinase))
VroAM7_45500	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
VroAM7_45600	COG0583	DNA-binding transcription factor activity
VroAM7_45640	COG0583	DNA-binding transcription factor activity
VroAM7_45690	COG2814	Major facilitator Superfamily
VroAM7_45700	COG1335	isochorismatase
VroAM7_45730	COG2194	sulfuric ester hydrolase activity
VroAM7_45740	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VroAM7_45760	COG2205	protein histidine kinase activity
VroAM7_45770	COG0745	RESPONSE REGULATOR receiver
VroAM7_45790	COG4221	oxidoreductase activity
VroAM7_45820	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VroAM7_45860	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VroAM7_45880	COG2814	Major facilitator Superfamily
VroAM7_45910	COG1418	mRNA catabolic process
VroAM7_45940	COG0402	S-adenosylhomocysteine deaminase activity
VroAM7_45950	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
VroAM7_45960	COG2239	Acts as a magnesium transporter
VroAM7_45970	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
VroAM7_45980	COG1566	PFAM secretion protein HlyD family protein
VroAM7_46020	COG0745	RESPONSE REGULATOR receiver
VroAM7_46030	COG2205	protein histidine kinase activity
VroAM7_46060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VroAM7_46090	COG0531	amino acid
VroAM7_46160	COG5002	protein histidine kinase activity
VroAM7_46160	COG0784	Response regulator, receiver
VroAM7_46160	COG2205	protein histidine kinase activity
VroAM7_46170	COG0673	inositol 2-dehydrogenase activity
VroAM7_46190	COG2926	Belongs to the UPF0265 family
VroAM7_46220	COG2827	Endonuclease containing a URI domain
VroAM7_46230	COG1879	ABC-type sugar transport system periplasmic component
VroAM7_46260	COG1522	sequence-specific DNA binding
VroAM7_46320	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VroAM7_46330	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VroAM7_46350	COG1280	lysine exporter protein (LysE YggA)
VroAM7_46370	COG0183	Belongs to the thiolase family
VroAM7_46410	COG3005	denitrification pathway
VroAM7_46430	COG0243	molybdopterin cofactor binding
VroAM7_46450	COG3850	Histidine kinase
VroAM7_46460	COG2197	response regulator
VroAM7_46490	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
VroAM7_46490	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
VroAM7_46550	COG1061	Type III restriction enzyme res subunit
VroAM7_46630	COG2204	response regulator
VroAM7_46650	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VroAM7_46800	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VroAM7_46810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VroAM7_46850	COG2203	Gaf domain
VroAM7_46850	COG3706	GGDEF domain
VroAM7_46850	COG4251	negative regulation of phosphorylation
VroAM7_46850	COG5001	Diguanylate cyclase
VroAM7_46940	COG2200	EAL domain
VroAM7_46940	COG2199	diguanylate cyclase activity
VroAM7_46960	COG4969	Belongs to the N-Me-Phe pilin family
VroAM7_46980	COG0076	glutamate decarboxylase activity
VroAM7_47040	COG4176	ABC-type proline glycine betaine transport system permease component
VroAM7_47050	COG4175	Glycine betaine
VroAM7_47050	COG0517	IMP dehydrogenase activity
VroAM7_47080	COG0330	HflC and HflK could
VroAM7_47100	COG2202	Pas domain
VroAM7_47100	COG2200	EAL domain
VroAM7_47100	COG2199	diguanylate cyclase activity
VroAM7_47120	COG5001	Diguanylate cyclase
VroAM7_47120	COG3706	GGDEF domain
VroAM7_47120	COG4251	negative regulation of phosphorylation
VroAM7_47120	COG2203	Gaf domain
VroAM7_47130	COG2205	protein histidine kinase activity
VroAM7_47130	COG0784	Response regulator, receiver
VroAM7_47180	COG1619	proteins homologs of microcin C7 resistance protein MccF
VroAM7_47190	COG2133	pyrroloquinoline quinone binding
VroAM7_47200	COG1454	alcohol dehydrogenase
VroAM7_47210	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
VroAM7_47270	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VroAM7_47280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VroAM7_47300	COG3186	Phenylalanine-4-hydroxylase
VroAM7_47370	COG3530	Putative quorum-sensing-regulated virulence factor
VroAM7_47430	COG0523	cobalamin synthesis protein
VroAM7_47440	COG0513	Belongs to the DEAD box helicase family
VroAM7_47490	COG2200	EAL domain
VroAM7_47500	COG1119	ATPase activity
VroAM7_47520	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VroAM7_47550	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
VroAM7_47560	COG0513	Belongs to the DEAD box helicase family
VroAM7_47570	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VroAM7_47620	COG3278	Belongs to the heme-copper respiratory oxidase family
VroAM7_47690	COG1024	Enoyl-CoA hydratase
VroAM7_47700	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
VroAM7_47710	COG1960	acyl-CoA dehydrogenase activity
VroAM7_47730	COG0183	Belongs to the thiolase family
VroAM7_47760	COG1024	Enoyl-CoA hydratase
VroAM7_47770	COG1024	Enoyl-CoA hydratase
VroAM7_47790	COG1028	Short-chain dehydrogenase reductase Sdr
VroAM7_47820	COG1902	pentaerythritol trinitrate reductase activity
VroAM7_47820	COG0446	pyridine nucleotide-disulphide oxidoreductase
VroAM7_47830	COG0583	DNA-binding transcription factor activity
VroAM7_47850	COG1012	belongs to the aldehyde dehydrogenase family
VroAM7_47870	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VroAM7_47930	COG1126	abc transporter atp-binding protein
VroAM7_47940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VroAM7_47950	COG4215	(ABC) transporter
VroAM7_47960	COG4160	amino acid transport
VroAM7_48030	COG1538	Outer membrane efflux protein
VroAM7_48110	COG2249	NAD(P)H dehydrogenase (quinone) activity
VroAM7_48120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VroAM7_48150	COG0443	Heat shock 70 kDa protein
VroAM7_48190	COG0745	RESPONSE REGULATOR receiver
VroAM7_48200	COG0003	Pfam Anion-transporting ATPase
VroAM7_48210	COG0545	Peptidyl-prolyl cis-trans isomerase
VroAM7_48230	COG2885	chlorophyll binding
VroAM7_48270	COG1278	Cold shock
VroAM7_48280	COG3036	rescue of stalled ribosome
VroAM7_48300	COG2203	Gaf domain
VroAM7_48300	COG2199	diguanylate cyclase activity
VroAM7_48340	COG1136	(ABC) transporter
VroAM7_48370	COG0783	Belongs to the Dps family
VroAM7_48570	COG3501	Rhs element vgr protein
VroAM7_48590	COG0666	response to abiotic stimulus
VroAM7_48630	COG3209	COG3209 Rhs family protein
VroAM7_48660	COG3209	COG3209 Rhs family protein
VroAM7_49510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VroAM7_49750	COG0210	DNA helicase
VroAM7_49930	COG1196	nuclear chromosome segregation
VroAM7_49970	COG0330	HflC and HflK could
VroAM7_50010	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
VroAM7_50570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
VroAM7_50640	COG3842	ATPase activity
VroAM7_50850	COG1192	Involved in chromosome partitioning
VroAM7_50870	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
VroAM7_50890	COG0732	type I restriction modification DNA specificity domain
VroAM7_50900	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VroAM7_50950	COG2197	response regulator
VroAM7_51000	COG0583	DNA-binding transcription factor activity
VroAM7_51050	COG2313	pseudouridylate synthase activity
VroAM7_51120	COG4251	negative regulation of phosphorylation
VroAM7_51130	COG2197	response regulator
VroAM7_51150	COG4584	PFAM Integrase catalytic
VroAM7_51160	COG1484	DNA-dependent DNA replication
VroAM7_51170	COG5001	Diguanylate cyclase
VroAM7_51170	COG3300	MHYT domain
VroAM7_51190	COG3706	GGDEF domain