locus-tag	class	description
VSVS05_00004	COG1573	uracil-dna glycosylase
VSVS05_00005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VSVS05_00006	COG3068	Protein conserved in bacteria
VSVS05_00007	COG1253	flavin adenine dinucleotide binding
VSVS05_00010	COG0151	Belongs to the GarS family
VSVS05_00011	COG0138	bifunctional purine biosynthesis protein purh
VSVS05_00012	COG0789	Transcriptional regulator
VSVS05_00013	COG3706	GGDEF domain
VSVS05_00014	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VSVS05_00017	COG0439	Biotin carboxylase
VSVS05_00018	COG0511	ligase activity, forming carbon-carbon bonds
VSVS05_00019	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VSVS05_00020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VSVS05_00023	COG2814	Major facilitator Superfamily
VSVS05_00026	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VSVS05_00028	COG2095	MarC family integral membrane protein
VSVS05_00030	COG4232	protein-disulfide reductase activity
VSVS05_00031	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VSVS05_00032	COG1027	Aspartate ammonia-lyase
VSVS05_00034	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
VSVS05_00035	COG2205	protein histidine kinase activity
VSVS05_00036	COG0745	RESPONSE REGULATOR receiver
VSVS05_00037	COG3678	ATP-independent chaperone mediated protein folding
VSVS05_00038	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
VSVS05_00042	COG1509	lysine 2,3-aminomutase activity
VSVS05_00044	COG1575	Belongs to the MenA family. Type 1 subfamily
VSVS05_00045	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VSVS05_00046	COG0534	Mate efflux family protein
VSVS05_00050	COG1072	(Pantothenic acid kinase))
VSVS05_00056	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VSVS05_00057	COG0250	Participates in transcription elongation, termination and antitermination
VSVS05_00058	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
VSVS05_00060	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
VSVS05_00062	COG0085	RNA polymerase activity
VSVS05_00063	COG0085	RNA polymerase activity
VSVS05_00065	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
VSVS05_00070	COG4942	peptidase
VSVS05_00073	COG3273	potassium ion transport
VSVS05_00073	COG0471	metal ion transport
VSVS05_00074	COG0688	phosphatidylethanolamine metabolic process
VSVS05_00075	COG1162	GTPase activity
VSVS05_00089	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VSVS05_00090	COG0802	atpase or kinase
VSVS05_00091	COG0860	N-Acetylmuramoyl-L-alanine amidase
VSVS05_00092	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
VSVS05_00095	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VSVS05_00096	COG0330	HflC and HflK could
VSVS05_00097	COG0330	HflC and HflK could
VSVS05_00098	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
VSVS05_00101	COG0545	Peptidyl-prolyl cis-trans isomerase
VSVS05_00102	COG2964	Protein conserved in bacteria
VSVS05_00104	COG2923	Belongs to the DsrF TusC family
VSVS05_00107	COG0049	tRNA binding
VSVS05_00108	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VSVS05_00110	COG2906	2 iron, 2 sulfur cluster binding
VSVS05_00112	COG0360	Binds together with S18 to 16S ribosomal RNA
VSVS05_00113	COG2965	DNA replication, synthesis of RNA primer
VSVS05_00117	COG0305	Participates in initiation and elongation during chromosome replication
VSVS05_00118	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VSVS05_00119	COG0432	Pfam Uncharacterised protein family UPF0047
VSVS05_00128	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VSVS05_00129	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VSVS05_00130	COG0729	surface antigen
VSVS05_00131	COG2911	Protein conserved in bacteria
VSVS05_00132	COG2105	PFAM AIG2 family protein
VSVS05_00135	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
VSVS05_00136	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VSVS05_00137	COG0163	prenyltransferase activity
VSVS05_00139	COG4143	(ABC) transporter
VSVS05_00140	COG1178	ABC-type Fe3 transport system permease component
VSVS05_00141	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
VSVS05_00142	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
VSVS05_00143	COG3028	Belongs to the UPF0307 family
VSVS05_00144	COG0312	modulator of DNA gyrase
VSVS05_00145	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VSVS05_00147	COG0189	ligase activity
VSVS05_00148	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VSVS05_00149	COG2356	endonuclease I
VSVS05_00150	COG3091	SprT-like family
VSVS05_00153	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VSVS05_00154	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VSVS05_00156	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VSVS05_00158	COG0191	fructose-bisphosphate aldolase activity
VSVS05_00159	COG0668	transmembrane transport
VSVS05_00163	COG0469	pyruvate kinase activity
VSVS05_00164	COG1349	DNA-binding transcription factor activity
VSVS05_00168	COG3916	Acyl-homoserine-lactone synthase
VSVS05_00170	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
VSVS05_00171	COG2076	Multidrug Resistance protein
VSVS05_00172	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VSVS05_00177	COG2252	PERMEase
VSVS05_00178	COG3706	GGDEF domain
VSVS05_00180	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VSVS05_00181	COG0358	DNA primase activity
VSVS05_00182	COG1610	YqeY-like protein
VSVS05_00183	COG0828	Belongs to the bacterial ribosomal protein bS21 family
VSVS05_00184	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
VSVS05_00185	COG0596	Alpha beta hydrolase
VSVS05_00186	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
VSVS05_00187	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
VSVS05_00188	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VSVS05_00190	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
VSVS05_00191	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VSVS05_00193	COG0585	pseudouridine synthase activity
VSVS05_00194	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
VSVS05_00196	COG1388	LysM domain
VSVS05_00196	COG4942	peptidase
VSVS05_00197	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VSVS05_00198	COG4536	flavin adenine dinucleotide binding
VSVS05_00199	COG4137	Cytochrome C assembly protein
VSVS05_00200	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VSVS05_00204	COG0335	large ribosomal subunit rRNA binding
VSVS05_00205	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
VSVS05_00206	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
VSVS05_00207	COG0237	dephospho-CoA kinase activity
VSVS05_00209	COG1459	type II secretion system
VSVS05_00210	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VSVS05_00213	COG1546	Belongs to the CinA family
VSVS05_00214	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VSVS05_00215	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
VSVS05_00216	COG0527	aspartate kinase activity
VSVS05_00217	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
VSVS05_00227	COG3630	sodium ion export across plasma membrane
VSVS05_00228	COG0511	ligase activity, forming carbon-carbon bonds
VSVS05_00228	COG5016	pyruvate
VSVS05_00229	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VSVS05_00231	COG1238	metal cluster binding
VSVS05_00232	COG0612	Peptidase, M16
VSVS05_00233	COG2918	glutathione biosynthetic process
VSVS05_00235	COG1854	S-ribosylhomocysteine lyase activity
VSVS05_00243	COG0741	lytic transglycosylase activity
VSVS05_00245	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
VSVS05_00246	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VSVS05_00247	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VSVS05_00248	COG1447	Phosphotransferase system cellobiose-specific component IIA
VSVS05_00249	COG1486	melibiose metabolic process
VSVS05_00250	COG3394	polysaccharide catabolic process
VSVS05_00251	COG1609	Transcriptional regulator
VSVS05_00262	COG0066	3-isopropylmalate dehydratase activity
VSVS05_00264	COG0473	3-isopropylmalate dehydrogenase activity
VSVS05_00268	COG0583	DNA-binding transcription factor activity
VSVS05_00269	COG1022	Amp-dependent synthetase and ligase
VSVS05_00270	COG0028	Belongs to the TPP enzyme family
VSVS05_00272	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VSVS05_00273	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
VSVS05_00274	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
VSVS05_00277	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VSVS05_00278	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VSVS05_00281	COG0354	folic acid binding
VSVS05_00282	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
VSVS05_00284	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VSVS05_00285	COG1595	DNA-templated transcription, initiation
VSVS05_00287	COG3026	antisigma factor binding
VSVS05_00288	COG3086	response to oxidative stress
VSVS05_00289	COG0481	GTPase activity
VSVS05_00290	COG0681	Belongs to the peptidase S26 family
VSVS05_00292	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VSVS05_00293	COG1381	Involved in DNA repair and RecF pathway recombination
VSVS05_00296	COG2205	protein histidine kinase activity
VSVS05_00296	COG3850	Histidine kinase
VSVS05_00296	COG4999	Histidine kinase
VSVS05_00296	COG3437	response regulator, receiver
VSVS05_00297	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VSVS05_00298	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VSVS05_00299	COG3956	TIGRFAM MazG family protein
VSVS05_00301	COG0148	phosphopyruvate hydratase activity
VSVS05_00302	COG0617	tRNA 3'-terminal CCA addition
VSVS05_00303	COG3267	Type II secretory pathway component ExeA
VSVS05_00303	COG3409	Peptidoglycan-binding domain 1 protein
VSVS05_00305	COG4991	sh3 domain protein
VSVS05_00306	COG0306	phosphate transporter
VSVS05_00307	COG1392	Phosphate transport regulator
VSVS05_00308	COG3025	triphosphatase activity
VSVS05_00309	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VSVS05_00311	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VSVS05_00313	COG0745	RESPONSE REGULATOR receiver
VSVS05_00315	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VSVS05_00319	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
VSVS05_00320	COG2860	membrane
VSVS05_00321	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VSVS05_00323	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VSVS05_00324	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VSVS05_00328	COG0534	Mate efflux family protein
VSVS05_00330	COG0737	Belongs to the 5'-nucleotidase family
VSVS05_00335	COG3153	acetyltransferase
VSVS05_00337	COG0456	acetyltransferase
VSVS05_00338	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
VSVS05_00339	COG0513	Belongs to the DEAD box helicase family
VSVS05_00340	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
VSVS05_00342	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
VSVS05_00344	COG2204	response regulator
VSVS05_00345	COG1538	Outer membrane efflux protein
VSVS05_00346	COG0494	nUDIX hydrolase
VSVS05_00347	COG3151	Protein conserved in bacteria
VSVS05_00349	COG3150	esterase
VSVS05_00350	COG0187	DNA topoisomerase II activity
VSVS05_00352	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VSVS05_00353	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VSVS05_00354	COG3105	Protein conserved in bacteria
VSVS05_00355	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VSVS05_00358	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
VSVS05_00359	COG0723	plastoquinol--plastocyanin reductase activity
VSVS05_00360	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VSVS05_00361	COG2857	Cytochrome c1
VSVS05_00362	COG0625	glutathione transferase activity
VSVS05_00363	COG2969	positive regulation of protein catabolic process
VSVS05_00364	COG2823	Periplasmic or secreted lipoprotein
VSVS05_00365	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VSVS05_00366	COG0792	nuclease activity
VSVS05_00367	COG3107	peptidoglycan biosynthetic process
VSVS05_00368	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VSVS05_00370	COG3116	cell division
VSVS05_00371	COG0768	penicillin binding
VSVS05_00372	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VSVS05_00373	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VSVS05_00374	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
VSVS05_00376	COG0772	Belongs to the SEDS family
VSVS05_00377	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
VSVS05_00379	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VSVS05_00380	COG0849	cell division
VSVS05_00381	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VSVS05_00382	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
VSVS05_00385	COG0494	nUDIX hydrolase
VSVS05_00387	COG0505	Belongs to the CarA family
VSVS05_00388	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VSVS05_00389	COG0730	response to heat
VSVS05_00390	COG0583	DNA-binding transcription factor activity
VSVS05_00391	COG3397	chitin binding
VSVS05_00392	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
VSVS05_00394	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
VSVS05_00397	COG1115	amino acid carrier protein
VSVS05_00398	COG3022	response to hydroperoxide
VSVS05_00400	COG0084	hydrolase, TatD family'
VSVS05_00401	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VSVS05_00403	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
VSVS05_00404	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
VSVS05_00405	COG0813	purine-nucleoside phosphorylase activity
VSVS05_00407	COG0560	Phosphoserine phosphatase
VSVS05_00409	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VSVS05_00411	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VSVS05_00412	COG0583	DNA-binding transcription factor activity
VSVS05_00414	COG1022	Amp-dependent synthetase and ligase
VSVS05_00415	COG2169	Transcriptional regulator
VSVS05_00420	COG4964	Belongs to the GSP D family
VSVS05_00431	COG0583	DNA-binding transcription factor activity
VSVS05_00437	COG2171	N-acyltransferase activity
VSVS05_00440	COG0450	alkyl hydroperoxide reductase
VSVS05_00441	COG0583	DNA-binding transcription factor activity
VSVS05_00442	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
VSVS05_00444	COG0517	IMP dehydrogenase activity
VSVS05_00446	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
VSVS05_00449	COG1862	Preprotein translocase
VSVS05_00450	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VSVS05_00451	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VSVS05_00453	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
VSVS05_00455	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VSVS05_00457	COG2974	May be involved in recombination
VSVS05_00459	COG5002	protein histidine kinase activity
VSVS05_00461	COG0248	Ppx GppA phosphatase
VSVS05_00463	COG0581	inorganic phosphate transmembrane transporter activity
VSVS05_00464	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VSVS05_00465	COG0704	Plays a role in the regulation of phosphate uptake
VSVS05_00470	COG3142	Participates in the control of copper homeostasis
VSVS05_00475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VSVS05_00476	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VSVS05_00477	COG3141	response to X-ray
VSVS05_00478	COG0583	DNA-binding transcription factor activity
VSVS05_00480	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VSVS05_00481	COG1074	ATP-dependent DNA helicase activity
VSVS05_00482	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VSVS05_00486	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
VSVS05_00487	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VSVS05_00488	COG2166	iron-sulfur cluster assembly
VSVS05_00489	COG0820	rRNA (adenine-C2-)-methyltransferase activity
VSVS05_00490	COG1426	Protein conserved in bacteria
VSVS05_00492	COG0124	histidyl-tRNA synthetase
VSVS05_00493	COG2976	Protein conserved in bacteria
VSVS05_00494	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VSVS05_00495	COG1160	GTP binding
VSVS05_00499	COG0516	GMP reductase activity
VSVS05_00499	COG0517	IMP dehydrogenase activity
VSVS05_00501	COG1757	Na H antiporter
VSVS05_00502	COG1584	GPR1 FUN34 yaaH family protein
VSVS05_00503	COG1115	amino acid carrier protein
VSVS05_00504	COG2873	o-acetylhomoserine
VSVS05_00505	COG2354	Protein conserved in bacteria
VSVS05_00506	COG2190	(PTS) system
VSVS05_00506	COG1263	PTS System
VSVS05_00506	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VSVS05_00508	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
VSVS05_00509	COG0840	transmembrane signaling receptor activity
VSVS05_00510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VSVS05_00510	COG3153	acetyltransferase
VSVS05_00512	COG0402	S-adenosylhomocysteine deaminase activity
VSVS05_00514	COG0668	transmembrane transport
VSVS05_00521	COG3335	DDE superfamily endonuclease
VSVS05_00535	COG2003	Belongs to the UPF0758 family
VSVS05_00548	COG2963	transposase activity
VSVS05_00551	COG0582	viral genome integration into host DNA
VSVS05_00553	COG2867	negative regulation of translational initiation
VSVS05_00554	COG2914	Belongs to the UPF0125 (RnfH) family
VSVS05_00555	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VSVS05_00556	COG0497	DNA recombination
VSVS05_00559	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VSVS05_00561	COG1301	dicarboxylic acid transport
VSVS05_00564	COG0484	heat shock protein binding
VSVS05_00570	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VSVS05_00571	COG1253	flavin adenine dinucleotide binding
VSVS05_00572	COG0590	tRNA wobble adenosine to inosine editing
VSVS05_00574	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
VSVS05_00575	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VSVS05_00575	COG0047	phosphoribosylformylglycinamidine synthase activity
VSVS05_00580	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VSVS05_00581	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
VSVS05_00582	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VSVS05_00583	COG1187	pseudouridine synthase activity
VSVS05_00584	COG2840	Smr protein MutS2
VSVS05_00588	COG3104	oligopeptide transport
VSVS05_00589	COG0367	asparagine synthase
VSVS05_00590	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VSVS05_00590	COG4651	solute:proton antiporter activity
VSVS05_00591	COG1940	carbohydrate kinase activity
VSVS05_00591	COG1846	Transcriptional regulator
VSVS05_00592	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VSVS05_00593	COG1263	PTS System
VSVS05_00593	COG2190	(PTS) system
VSVS05_00593	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VSVS05_00597	COG0716	FMN binding
VSVS05_00599	COG0596	Alpha beta hydrolase
VSVS05_00600	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
VSVS05_00601	COG0033	Phosphoglucomutase
VSVS05_00604	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VSVS05_00606	COG2009	succinate dehydrogenase
VSVS05_00607	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
VSVS05_00608	COG1053	succinate dehydrogenase
VSVS05_00609	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VSVS05_00610	COG0567	Dehydrogenase, E1 component
VSVS05_00611	COG0508	dehydrogenase complex catalyzes the overall conversion of
VSVS05_00612	COG0045	succinate-CoA ligase (ADP-forming) activity
VSVS05_00618	COG3098	single-species biofilm formation
VSVS05_00619	COG0564	pseudouridine synthase activity
VSVS05_00621	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
VSVS05_00622	COG0142	geranyltranstransferase activity
VSVS05_00624	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VSVS05_00625	COG1360	Flagellar Motor Protein
VSVS05_00626	COG0301	tRNA thio-modification
VSVS05_00626	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VSVS05_00629	COG0583	DNA-binding transcription factor activity
VSVS05_00631	COG2363	Small membrane protein
VSVS05_00632	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
VSVS05_00633	COG3385	transposase activity
VSVS05_00635	COG1611	Belongs to the LOG family
VSVS05_00636	COG3706	GGDEF domain
VSVS05_00638	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VSVS05_00638	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VSVS05_00640	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
VSVS05_00643	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VSVS05_00644	COG1393	Belongs to the ArsC family
VSVS05_00649	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
VSVS05_00651	COG0437	4 iron, 4 sulfur cluster binding
VSVS05_00652	COG3301	Polysulphide reductase, NrfD
VSVS05_00653	COG1138	Cytochrome C-type biogenesis protein
VSVS05_00655	COG3088	subunit of a heme lyase
VSVS05_00655	COG4235	cytochrome complex assembly
VSVS05_00657	COG2837	iron assimilation
VSVS05_00660	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VSVS05_00661	COG1334	flagellar protein FlaG
VSVS05_00662	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VSVS05_00664	COG1516	flagellar protein fliS
VSVS05_00665	COG2204	response regulator
VSVS05_00666	COG4191	Histidine kinase
VSVS05_00667	COG2204	response regulator
VSVS05_00668	COG1677	Flagellar hook-basal body complex protein FliE
VSVS05_00670	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VSVS05_00680	COG1987	bacterial-type flagellum assembly
VSVS05_00681	COG1684	flagellar biosynthetic protein fliR
VSVS05_00683	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
VSVS05_00684	COG2840	Smr protein MutS2
VSVS05_00685	COG2890	protein-(glutamine-N5) methyltransferase activity
VSVS05_00686	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
VSVS05_00687	COG2860	membrane
VSVS05_00688	COG3101	peptidyl-lysine hydroxylation
VSVS05_00695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VSVS05_00696	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VSVS05_00697	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VSVS05_00702	COG0285	dihydrofolate synthase activity
VSVS05_00703	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
VSVS05_00704	COG1286	toxin biosynthetic process
VSVS05_00705	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VSVS05_00706	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VSVS05_00707	COG1121	(ABC) transporter
VSVS05_00708	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
VSVS05_00710	COG1918	ferrous iron import across plasma membrane
VSVS05_00711	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
VSVS05_00715	COG3102	Protein conserved in bacteria
VSVS05_00716	COG1025	Belongs to the peptidase M16 family
VSVS05_00717	COG2062	phosphohistidine phosphatase, SixA
VSVS05_00720	COG0455	bacterial-type flagellum organization
VSVS05_00723	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
VSVS05_00724	COG0643	Histidine kinase
VSVS05_00724	COG2198	Histidine kinase
VSVS05_00725	COG2201	protein-glutamate methylesterase activity
VSVS05_00726	COG1192	Involved in chromosome partitioning
VSVS05_00728	COG0835	chemotaxis
VSVS05_00730	COG4133	protoheme IX ABC transporter activity
VSVS05_00731	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VSVS05_00732	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VSVS05_00735	COG1138	Cytochrome C-type biogenesis protein
VSVS05_00736	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VSVS05_00737	COG3088	subunit of a heme lyase
VSVS05_00737	COG4235	cytochrome complex assembly
VSVS05_00738	COG4235	cytochrome complex assembly
VSVS05_00740	COG2067	long-chain fatty acid transport protein
VSVS05_00742	COG3335	DDE superfamily endonuclease
VSVS05_00745	COG0183	Belongs to the thiolase family
VSVS05_00746	COG1250	3-hydroxyacyl-CoA dehydrogenase
VSVS05_00746	COG1024	Enoyl-CoA hydratase
VSVS05_00747	COG0778	Nitroreductase
VSVS05_00748	COG0583	DNA-binding transcription factor activity
VSVS05_00749	COG0745	RESPONSE REGULATOR receiver
VSVS05_00752	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
VSVS05_00753	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
VSVS05_00754	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
VSVS05_00756	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VSVS05_00757	COG2188	Transcriptional regulator
VSVS05_00761	COG0667	Aldo Keto reductase
VSVS05_00763	COG2261	transglycosylase associated protein
VSVS05_00765	COG0668	transmembrane transport
VSVS05_00768	COG2226	methyltransferase
VSVS05_00770	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VSVS05_00771	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VSVS05_00773	COG3139	Protein of unknown function (DUF1315)
VSVS05_00774	COG3012	SEC-C Motif Domain Protein
VSVS05_00775	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VSVS05_00777	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VSVS05_00779	COG1435	thymidine kinase activity
VSVS05_00780	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VSVS05_00781	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
VSVS05_00782	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
VSVS05_00783	COG3134	Outer membrane lipoprotein
VSVS05_00784	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
VSVS05_00786	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VSVS05_00787	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VSVS05_00789	COG0596	Alpha beta hydrolase
VSVS05_00792	COG3070	regulator of competence-specific genes
VSVS05_00793	COG1609	Transcriptional regulator
VSVS05_00794	COG3381	protein complex oligomerization
VSVS05_00795	COG0745	RESPONSE REGULATOR receiver
VSVS05_00796	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VSVS05_00797	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VSVS05_00798	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
VSVS05_00799	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
VSVS05_00801	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
VSVS05_00804	COG0189	ligase activity
VSVS05_00804	COG4067	protein conserved in archaea
VSVS05_00806	COG4106	trans-aconitate 2-methyltransferase activity
VSVS05_00807	COG1801	Protein of unknown function DUF72
VSVS05_00808	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
VSVS05_00809	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VSVS05_00810	COG4232	protein-disulfide reductase activity
VSVS05_00811	COG1187	pseudouridine synthase activity
VSVS05_00813	COG1278	Cold shock
VSVS05_00814	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
VSVS05_00815	COG0542	response to heat
VSVS05_00816	COG0542	response to heat
VSVS05_00819	COG0583	DNA-binding transcription factor activity
VSVS05_00823	COG2116	formate transmembrane transporter activity
VSVS05_00825	COG0390	transport system, permease component
VSVS05_00826	COG4459	periplasmic nitrate reductase
VSVS05_00827	COG3005	denitrification pathway
VSVS05_00828	COG0243	molybdopterin cofactor binding
VSVS05_00832	COG2255	four-way junction helicase activity
VSVS05_00833	COG1271	oxidase subunit
VSVS05_00834	COG1294	oxidase, subunit
VSVS05_00835	COG4890	Cyd operon protein YbgT
VSVS05_00837	COG0824	Thioesterase
VSVS05_00838	COG0811	peptide transport
VSVS05_00842	COG2885	chlorophyll binding
VSVS05_00843	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
VSVS05_00844	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
VSVS05_00847	COG2205	protein histidine kinase activity
VSVS05_00847	COG0784	Response regulator, receiver
VSVS05_00853	COG4260	virion core protein, lumpy skin disease virus
VSVS05_00856	COG5413	integral membrane protein
VSVS05_00857	COG0402	S-adenosylhomocysteine deaminase activity
VSVS05_00859	COG0784	Response regulator, receiver
VSVS05_00859	COG2205	protein histidine kinase activity
VSVS05_00860	COG1858	cytochrome C peroxidase
VSVS05_00864	COG5002	protein histidine kinase activity
VSVS05_00864	COG3850	Histidine kinase
VSVS05_00865	COG0745	RESPONSE REGULATOR receiver
VSVS05_00866	COG0463	Glycosyl transferase, family 2
VSVS05_00867	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
VSVS05_00869	COG1309	transcriptional regulator
VSVS05_00870	COG1960	acyl-CoA dehydrogenase activity
VSVS05_00871	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VSVS05_00873	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VSVS05_00875	COG0708	Exodeoxyribonuclease III
VSVS05_00876	COG2850	peptidyl-arginine hydroxylation
VSVS05_00878	COG3923	Primosomal replication protein n
VSVS05_00879	COG0730	response to heat
VSVS05_00880	COG1199	ATP-dependent helicase activity
VSVS05_00883	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
VSVS05_00885	COG0156	8-amino-7-oxononanoate synthase activity
VSVS05_00886	COG2226	methyltransferase
VSVS05_00887	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
VSVS05_00891	COG1028	Short-chain dehydrogenase reductase Sdr
VSVS05_00894	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VSVS05_00899	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VSVS05_00901	COG0482	sulfurtransferase activity
VSVS05_00903	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VSVS05_00904	COG2916	Histone family protein nucleoid-structuring protein H-NS
VSVS05_00905	COG1757	Na H antiporter
VSVS05_00907	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
VSVS05_00908	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VSVS05_00909	COG0131	Imidazoleglycerol-phosphate dehydratase
VSVS05_00909	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VSVS05_00910	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VSVS05_00912	COG0107	imidazoleglycerol-phosphate synthase activity
VSVS05_00915	COG1227	inorganic diphosphatase activity
VSVS05_00916	COG4172	Belongs to the ABC transporter superfamily
VSVS05_00918	COG4171	peptide transport system, permease
VSVS05_00919	COG4168	peptide transport system, permease
VSVS05_00921	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
VSVS05_00922	COG1842	Phage shock protein A
VSVS05_00926	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VSVS05_00927	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VSVS05_00928	COG2818	Glycosylase
VSVS05_00929	COG0626	cystathionine gamma-synthase activity
VSVS05_00931	COG0733	neurotransmitter:sodium symporter activity
VSVS05_00933	COG0564	pseudouridine synthase activity
VSVS05_00936	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VSVS05_00937	COG4136	ATPase activity
VSVS05_00938	COG4135	transport system, permease component
VSVS05_00939	COG4134	Bacterial extracellular solute-binding protein
VSVS05_00941	COG3313	Fe-S protein
VSVS05_00945	COG2350	Protein conserved in bacteria
VSVS05_00946	COG1607	acyl-coa hydrolase
VSVS05_00954	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VSVS05_00955	COG0417	DNA replication proofreading
VSVS05_00958	COG2197	response regulator
VSVS05_00959	COG0322	excinuclease ABC activity
VSVS05_00966	COG3706	GGDEF domain
VSVS05_00969	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
VSVS05_00971	COG0745	RESPONSE REGULATOR receiver
VSVS05_00971	COG3706	GGDEF domain
VSVS05_00975	COG0072	phenylalanine-tRNA ligase activity
VSVS05_00975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VSVS05_00978	COG0534	Mate efflux family protein
VSVS05_00979	COG0583	DNA-binding transcription factor activity
VSVS05_00982	COG0110	maltose O-acetyltransferase activity
VSVS05_00984	COG2188	Transcriptional regulator
VSVS05_00987	COG1252	NADH dehydrogenase
VSVS05_00988	COG1301	dicarboxylic acid transport
VSVS05_00990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VSVS05_00992	COG0840	transmembrane signaling receptor activity
VSVS05_00994	COG0513	Belongs to the DEAD box helicase family
VSVS05_00997	COG0583	DNA-binding transcription factor activity
VSVS05_00999	COG1012	belongs to the aldehyde dehydrogenase family
VSVS05_01002	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VSVS05_01016	COG0596	Alpha beta hydrolase
VSVS05_01026	COG3341	Caulimovirus viroplasmin
VSVS05_01026	COG0328	RNA-DNA hybrid ribonuclease activity
VSVS05_01031	COG1187	pseudouridine synthase activity
VSVS05_01032	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VSVS05_01033	COG1263	PTS System
VSVS05_01033	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VSVS05_01035	COG2149	membrane
VSVS05_01040	COG2015	COG2015, Alkyl sulfatase and related hydrolases
VSVS05_01042	COG1403	HNH endonuclease
VSVS05_01044	COG2837	iron assimilation
VSVS05_01048	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VSVS05_01049	COG2030	dehydratase
VSVS05_01050	COG4670	ketone body catabolic process
VSVS05_01051	COG0583	DNA-binding transcription factor activity
VSVS05_01052	COG1028	Short-chain dehydrogenase reductase Sdr
VSVS05_01053	COG0183	Belongs to the thiolase family
VSVS05_01054	COG0484	heat shock protein binding
VSVS05_01055	COG0443	Heat shock 70 kDa protein
VSVS05_01057	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VSVS05_01058	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VSVS05_01060	COG0701	Predicted permease
VSVS05_01061	COG1028	Short-chain dehydrogenase reductase Sdr
VSVS05_01062	COG3385	transposase activity
VSVS05_01064	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VSVS05_01066	COG3383	formate dehydrogenase (NAD+) activity
VSVS05_01075	COG5433	transposase activity
VSVS05_01076	COG2226	methyltransferase
VSVS05_01079	COG3620	sequence-specific DNA binding
VSVS05_01083	COG5002	protein histidine kinase activity
VSVS05_01083	COG5001	Diguanylate cyclase
VSVS05_01083	COG3447	MASE1 domain protein
VSVS05_01092	COG0446	pyridine nucleotide-disulphide oxidoreductase
VSVS05_01097	COG0840	transmembrane signaling receptor activity
VSVS05_01103	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VSVS05_01107	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VSVS05_01108	COG1280	lysine exporter protein (LysE YggA)
VSVS05_01109	COG1115	amino acid carrier protein
VSVS05_01115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VSVS05_01115	COG4191	Histidine kinase
VSVS05_01117	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VSVS05_01118	COG1032	radical SAM domain protein
VSVS05_01122	COG0583	DNA-binding transcription factor activity
VSVS05_01123	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
VSVS05_01125	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VSVS05_01155	COG3772	lysozyme
VSVS05_01157	COG4695	Portal protein
VSVS05_01165	COG4386	tail sheath protein
VSVS05_01170	COG1454	alcohol dehydrogenase
VSVS05_01170	COG1012	belongs to the aldehyde dehydrogenase family
VSVS05_01171	COG1737	Transcriptional regulator
VSVS05_01172	COG0076	glutamate decarboxylase activity
VSVS05_01174	COG2431	L-lysine efflux transmembrane transporter activity
VSVS05_01175	COG2431	L-lysine efflux transmembrane transporter activity
VSVS05_01177	COG3070	regulator of competence-specific genes
VSVS05_01181	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VSVS05_01186	COG2195	Cleaves the N-terminal amino acid of tripeptides
VSVS05_01188	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
VSVS05_01189	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
VSVS05_01191	COG0625	glutathione transferase activity
VSVS05_01197	COG0247	lactate metabolic process
VSVS05_01197	COG0277	FAD linked oxidase domain protein
VSVS05_01199	COG4160	amino acid transport
VSVS05_01200	COG4215	(ABC) transporter
VSVS05_01201	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VSVS05_01202	COG1126	abc transporter atp-binding protein
VSVS05_01206	COG2986	histidine ammonia-lyase
VSVS05_01207	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
VSVS05_01209	COG1228	amidohydrolase
VSVS05_01210	COG2188	Transcriptional regulator
VSVS05_01211	COG4326	sporulation control protein
VSVS05_01215	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
VSVS05_01216	COG0471	metal ion transport
VSVS05_01217	COG4191	Histidine kinase
VSVS05_01217	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VSVS05_01221	COG1346	cytolysis
VSVS05_01223	COG2925	Exonuclease
VSVS05_01224	COG0251	oxidation-reduction process
VSVS05_01226	COG0702	epimerase
VSVS05_01227	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
VSVS05_01229	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
VSVS05_01234	COG4139	cobalamin transport
VSVS05_01235	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
VSVS05_01239	COG2814	Major facilitator Superfamily
VSVS05_01240	COG0583	DNA-binding transcription factor activity
VSVS05_01241	COG1914	H( )-stimulated, divalent metal cation uptake system
VSVS05_01244	COG1451	nucleotide metabolic process
VSVS05_01247	COG3063	Type IV pilus biogenesis stability protein PilW
VSVS05_01252	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VSVS05_01256	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VSVS05_01259	COG0840	transmembrane signaling receptor activity
VSVS05_01260	COG0602	queuosine metabolic process
VSVS05_01262	COG3706	GGDEF domain
VSVS05_01269	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VSVS05_01271	COG1254	Belongs to the acylphosphatase family
VSVS05_01272	COG2920	part of a sulfur-relay system
VSVS05_01273	COG0670	Belongs to the BI1 family
VSVS05_01274	COG1126	abc transporter atp-binding protein
VSVS05_01275	COG0765	amino acid transport
VSVS05_01276	COG4597	amino acid ABC transporter
VSVS05_01277	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VSVS05_01279	COG1666	GTP binding
VSVS05_01280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VSVS05_01285	COG3008	intermembrane lipid transfer
VSVS05_01286	COG3008	intermembrane lipid transfer
VSVS05_01287	COG2995	paraquat-inducible protein a
VSVS05_01288	COG1132	(ABC) transporter
VSVS05_01289	COG1956	GAF domain-containing protein
VSVS05_01290	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
VSVS05_01293	COG0308	aminopeptidase N
VSVS05_01298	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VSVS05_01298	COG0116	Belongs to the methyltransferase superfamily
VSVS05_01300	COG0488	(ABC) transporter
VSVS05_01303	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VSVS05_01304	COG1067	ATP-dependent peptidase activity
VSVS05_01305	COG3120	sequence-specific DNA binding
VSVS05_01308	COG3278	Belongs to the heme-copper respiratory oxidase family
VSVS05_01311	COG2010	Cytochrome c
VSVS05_01313	COG2217	Heavy metal translocating P-type atpase
VSVS05_01316	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VSVS05_01317	COG0589	response to stress
VSVS05_01322	COG3842	ATPase activity
VSVS05_01323	COG1176	ABC-type spermidine putrescine transport system, permease component I
VSVS05_01324	COG1177	transmembrane transport
VSVS05_01325	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VSVS05_01326	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VSVS05_01327	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VSVS05_01329	COG0004	ammonium transporteR
VSVS05_01332	COG0437	4 iron, 4 sulfur cluster binding
VSVS05_01333	COG0243	molybdopterin cofactor binding
VSVS05_01333	COG3383	formate dehydrogenase (NAD+) activity
VSVS05_01339	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VSVS05_01341	COG0488	(ABC) transporter
VSVS05_01345	COG4191	Histidine kinase
VSVS05_01346	COG2204	response regulator
VSVS05_01348	COG4662	Binding-protein-dependent transport system inner membrane component
VSVS05_01349	COG1122	ATPase activity
VSVS05_01353	COG1940	carbohydrate kinase activity
VSVS05_01357	COG0791	NLP P60 protein
VSVS05_01361	COG0307	riboflavin synthase, alpha
VSVS05_01362	COG0534	Mate efflux family protein
VSVS05_01363	COG0534	Mate efflux family protein
VSVS05_01366	COG1280	lysine exporter protein (LysE YggA)
VSVS05_01372	COG0583	DNA-binding transcription factor activity
VSVS05_01381	COG0583	DNA-binding transcription factor activity
VSVS05_01385	COG1263	PTS System
VSVS05_01385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VSVS05_01387	COG1737	Transcriptional regulator
VSVS05_01388	COG1793	dna ligase
VSVS05_01393	COG3437	response regulator, receiver
VSVS05_01393	COG4999	Histidine kinase
VSVS05_01393	COG3850	Histidine kinase
VSVS05_01393	COG2205	protein histidine kinase activity
VSVS05_01394	COG2204	response regulator
VSVS05_01396	COG0438	transferase activity, transferring glycosyl groups
VSVS05_01404	COG0297	glycogen (starch) synthase activity
VSVS05_01406	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VSVS05_01409	COG3706	GGDEF domain
VSVS05_01410	COG0724	RNA recognition motif
VSVS05_01411	COG1940	carbohydrate kinase activity
VSVS05_01416	COG1126	abc transporter atp-binding protein
VSVS05_01417	COG0765	amino acid transport
VSVS05_01418	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VSVS05_01419	COG4597	amino acid ABC transporter
VSVS05_01422	COG0848	biopolymer transport protein
VSVS05_01423	COG0811	peptide transport
VSVS05_01424	COG0811	peptide transport
VSVS05_01426	COG4774	siderophore transport
VSVS05_01427	COG2205	protein histidine kinase activity
VSVS05_01428	COG0745	RESPONSE REGULATOR receiver
VSVS05_01431	COG0584	glycerophosphoryl diester phosphodiesterase
VSVS05_01433	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
VSVS05_01435	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VSVS05_01436	COG1328	CTP reductase activity
VSVS05_01437	COG0840	transmembrane signaling receptor activity
VSVS05_01438	COG0840	transmembrane signaling receptor activity
VSVS05_01442	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VSVS05_01443	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VSVS05_01444	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VSVS05_01445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VSVS05_01450	COG0840	transmembrane signaling receptor activity
VSVS05_01451	COG0019	diaminopimelate decarboxylase activity
VSVS05_01457	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VSVS05_01460	COG1136	(ABC) transporter
VSVS05_01461	COG0534	Mate efflux family protein
VSVS05_01462	COG0702	epimerase
VSVS05_01463	COG5001	Diguanylate cyclase
VSVS05_01463	COG5002	protein histidine kinase activity
VSVS05_01464	COG1115	amino acid carrier protein
VSVS05_01467	COG3385	transposase activity
VSVS05_01469	COG2814	Major facilitator Superfamily
VSVS05_01471	COG1061	Type III restriction enzyme res subunit
VSVS05_01474	COG2205	protein histidine kinase activity
VSVS05_01477	COG0586	Pfam SNARE associated Golgi protein
VSVS05_01484	COG0783	Belongs to the Dps family
VSVS05_01486	COG1609	Transcriptional regulator
VSVS05_01488	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VSVS05_01489	COG1447	Phosphotransferase system cellobiose-specific component IIA
VSVS05_01495	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VSVS05_01498	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VSVS05_01499	COG3108	Peptidase M15
VSVS05_01500	COG2989	Protein conserved in bacteria
VSVS05_01506	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VSVS05_01510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VSVS05_01511	COG3283	Transcriptional regulator of aromatic amino acids metabolism
VSVS05_01513	COG3106	COG3106 Predicted ATPase
VSVS05_01517	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VSVS05_01518	COG2205	protein histidine kinase activity
VSVS05_01518	COG0784	Response regulator, receiver
VSVS05_01520	COG0494	nUDIX hydrolase
VSVS05_01521	COG0814	amino acid
VSVS05_01522	COG1760	l-serine dehydratase
VSVS05_01524	COG0720	synthase
VSVS05_01525	COG0840	transmembrane signaling receptor activity
VSVS05_01527	COG0017	Asparaginyl-tRNA synthetase
VSVS05_01531	COG1448	Aminotransferase
VSVS05_01534	COG1643	Atp-dependent helicase
VSVS05_01535	COG0281	malic enzyme
VSVS05_01537	COG2949	membrane
VSVS05_01538	COG3706	GGDEF domain
VSVS05_01538	COG0745	RESPONSE REGULATOR receiver
VSVS05_01542	COG0492	ferredoxin-NADP+ reductase activity
VSVS05_01543	COG4988	ABC transporter
VSVS05_01544	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
VSVS05_01545	COG0006	proline dipeptidase activity
VSVS05_01546	COG1522	sequence-specific DNA binding
VSVS05_01547	COG1012	belongs to the aldehyde dehydrogenase family
VSVS05_01548	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
VSVS05_01553	COG0513	Belongs to the DEAD box helicase family
VSVS05_01566	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VSVS05_01567	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
VSVS05_01568	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
VSVS05_01571	COG0242	peptide deformylase activity
VSVS05_01575	COG3437	response regulator, receiver
VSVS05_01576	COG0784	Response regulator, receiver
VSVS05_01576	COG5002	protein histidine kinase activity
VSVS05_01576	COG2205	protein histidine kinase activity
VSVS05_01577	COG1187	pseudouridine synthase activity
VSVS05_01578	COG0009	L-threonylcarbamoyladenylate synthase
VSVS05_01579	COG0613	PHP domain protein
VSVS05_01580	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VSVS05_01581	COG0512	Glutamine amidotransferase of anthranilate synthase
VSVS05_01582	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
VSVS05_01583	COG0135	phosphoribosylanthranilate isomerase activity
VSVS05_01583	COG0134	indole-3-glycerol-phosphate synthase activity
VSVS05_01584	COG0133	tryptophan synthase activity
VSVS05_01586	COG1301	dicarboxylic acid transport
VSVS05_01589	COG1643	Atp-dependent helicase
VSVS05_01596	COG3706	GGDEF domain
VSVS05_01599	COG0443	Heat shock 70 kDa protein
VSVS05_01601	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VSVS05_01608	COG1136	(ABC) transporter
VSVS05_01609	COG4591	ABC-type transport system involved in lipoprotein release permease component
VSVS05_01612	COG3275	phosphorelay sensor kinase activity
VSVS05_01614	COG4160	amino acid transport
VSVS05_01615	COG4215	(ABC) transporter
VSVS05_01616	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VSVS05_01619	COG1882	Formate acetyltransferase
VSVS05_01621	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VSVS05_01625	COG3713	MltA-interacting MipA family protein
VSVS05_01626	COG2766	serine protein kinase
VSVS05_01628	COG2719	SpoVR family
VSVS05_01629	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
VSVS05_01632	COG1132	(ABC) transporter
VSVS05_01633	COG0658	competence protein
VSVS05_01633	COG2333	competence protein COMEC
VSVS05_01634	COG0658	competence protein
VSVS05_01634	COG2333	competence protein COMEC
VSVS05_01637	COG4591	ABC-type transport system involved in lipoprotein release permease component
VSVS05_01638	COG1136	(ABC) transporter
VSVS05_01639	COG4591	ABC-type transport system involved in lipoprotein release permease component
VSVS05_01641	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
VSVS05_01644	COG1252	NADH dehydrogenase
VSVS05_01650	COG0537	adenosine 5'-monophosphoramidase activity
VSVS05_01653	COG3604	Transcriptional regulator
VSVS05_01654	COG1151	hydroxylamine reductase activity
VSVS05_01655	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VSVS05_01656	COG2186	Transcriptional regulator
VSVS05_01659	COG1674	ftsk spoiiie
VSVS05_01660	COG1522	sequence-specific DNA binding
VSVS05_01661	COG0686	Belongs to the AlaDH PNT family
VSVS05_01662	COG3092	negative regulation of chromosome organization
VSVS05_01664	COG0280	phosphate acetyltransferase
VSVS05_01664	COG0857	belongs to the CobB CobQ family
VSVS05_01666	COG3302	dmso reductase anchor subunit
VSVS05_01667	COG0437	4 iron, 4 sulfur cluster binding
VSVS05_01668	COG0243	molybdopterin cofactor binding
VSVS05_01669	COG3381	protein complex oligomerization
VSVS05_01670	COG2221	Nitrite and sulphite reductase 4Fe-4S
VSVS05_01670	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VSVS05_01679	COG0435	Glutathione S-transferase
VSVS05_01681	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VSVS05_01683	COG0444	Belongs to the ABC transporter superfamily
VSVS05_01684	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VSVS05_01685	COG0601	transmembrane transport
VSVS05_01687	COG4221	oxidoreductase activity
VSVS05_01690	COG5001	Diguanylate cyclase
VSVS05_01690	COG3300	MHYT domain
VSVS05_01694	COG3064	Membrane
VSVS05_01696	COG5002	protein histidine kinase activity
VSVS05_01696	COG5001	Diguanylate cyclase
VSVS05_01700	COG1946	Acyl-CoA thioesterase
VSVS05_01701	COG1522	sequence-specific DNA binding
VSVS05_01702	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VSVS05_01706	COG0477	Major facilitator Superfamily
VSVS05_01707	COG2855	membrane
VSVS05_01709	COG0583	DNA-binding transcription factor activity
VSVS05_01710	COG1263	PTS System
VSVS05_01710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VSVS05_01710	COG2190	(PTS) system
VSVS05_01711	COG0318	PFAM AMP-dependent synthetase and ligase
VSVS05_01712	COG1441	menaquinone biosynthetic process
VSVS05_01713	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
VSVS05_01715	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
VSVS05_01716	COG1169	isochorismate synthase
VSVS05_01717	COG0436	Aminotransferase
VSVS05_01718	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
VSVS05_01722	COG1349	DNA-binding transcription factor activity
VSVS05_01725	COG1278	Cold shock
VSVS05_01726	COG1349	DNA-binding transcription factor activity
VSVS05_01728	COG2222	sugar isomerase
VSVS05_01729	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VSVS05_01730	COG3715	PTS system
VSVS05_01731	COG3716	PTS system mannose fructose sorbose family IID component
VSVS05_01732	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
VSVS05_01735	COG0616	signal peptide processing
VSVS05_01736	COG1028	Short-chain dehydrogenase reductase Sdr
VSVS05_01740	COG0784	Response regulator, receiver
VSVS05_01740	COG0835	chemotaxis
VSVS05_01741	COG1940	carbohydrate kinase activity
VSVS05_01742	COG4667	esterase of the alpha-beta hydrolase superfamily
VSVS05_01746	COG0733	neurotransmitter:sodium symporter activity
VSVS05_01749	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VSVS05_01749	COG1263	PTS System
VSVS05_01751	COG0084	hydrolase, TatD family'
VSVS05_01753	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
VSVS05_01754	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VSVS05_01759	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
VSVS05_01760	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VSVS05_01763	COG1399	metal-binding, possibly nucleic acid-binding protein
VSVS05_01765	COG0564	pseudouridine synthase activity
VSVS05_01766	COG1530	ribonuclease E activity
VSVS05_01767	COG0659	secondary active sulfate transmembrane transporter activity
VSVS05_01768	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VSVS05_01771	COG0318	PFAM AMP-dependent synthetase and ligase
VSVS05_01772	COG2226	methyltransferase
VSVS05_01772	COG1073	alpha beta
VSVS05_01773	COG3065	identical protein binding
VSVS05_01775	COG1214	PFAM Peptidase M22, glycoprotease
VSVS05_01776	COG1199	ATP-dependent helicase activity
VSVS05_01778	COG0788	formyltetrahydrofolate deformylase activity
VSVS05_01780	COG0446	pyridine nucleotide-disulphide oxidoreductase
VSVS05_01780	COG1902	pentaerythritol trinitrate reductase activity
VSVS05_01781	COG0616	signal peptide processing
VSVS05_01782	COG0252	asparaginase activity
VSVS05_01784	COG2171	N-acyltransferase activity
VSVS05_01786	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
VSVS05_01787	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VSVS05_01791	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VSVS05_01792	COG1122	ATPase activity
VSVS05_01793	COG4120	Belongs to the binding-protein-dependent transport system permease family
VSVS05_01796	COG0583	DNA-binding transcription factor activity
VSVS05_01799	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VSVS05_01800	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
VSVS05_01802	COG0539	negative regulation of cytoplasmic translation
VSVS05_01803	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
VSVS05_01804	COG1555	photosystem II stabilization
VSVS05_01805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VSVS05_01806	COG0776	regulation of translation
VSVS05_01807	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VSVS05_01810	COG0544	peptidyl-prolyl cis-trans isomerase activity
VSVS05_01812	COG2204	response regulator
VSVS05_01813	COG1629	transport
VSVS05_01813	COG4771	TonB-dependent receptor
VSVS05_01814	COG0748	coenzyme F420 binding
VSVS05_01815	COG3721	Heme iron utilization protein
VSVS05_01818	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VSVS05_01819	COG0811	peptide transport
VSVS05_01820	COG0848	biopolymer transport protein
VSVS05_01822	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VSVS05_01823	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
VSVS05_01825	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VSVS05_01826	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VSVS05_01827	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VSVS05_01828	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VSVS05_01834	COG0625	glutathione transferase activity
VSVS05_01835	COG0443	Heat shock 70 kDa protein
VSVS05_01838	COG0800	Aldolase
VSVS05_01839	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VSVS05_01841	COG1028	Short-chain dehydrogenase reductase Sdr
VSVS05_01845	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
VSVS05_01847	COG3716	PTS system mannose fructose sorbose family IID component
VSVS05_01848	COG3715	PTS system
VSVS05_01849	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VSVS05_01850	COG1349	DNA-binding transcription factor activity
VSVS05_01854	COG1363	Peptidase, m42
VSVS05_01855	COG0006	proline dipeptidase activity
VSVS05_01856	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VSVS05_01857	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VSVS05_01858	COG1447	Phosphotransferase system cellobiose-specific component IIA
VSVS05_01859	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
VSVS05_01861	COG0415	Belongs to the DNA photolyase family
VSVS05_01862	COG3046	protein related to deoxyribodipyrimidine photolyase
VSVS05_01872	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
VSVS05_01875	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VSVS05_01876	COG1061	Type III restriction enzyme res subunit
VSVS05_01877	COG1002	Type II restriction enzyme, methylase subunits
VSVS05_01880	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VSVS05_01884	COG4974	Belongs to the 'phage' integrase family
VSVS05_01887	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VSVS05_01888	COG0583	DNA-binding transcription factor activity
VSVS05_01889	COG2951	lytic endotransglycosylase activity
VSVS05_01892	COG2894	cell division
VSVS05_01894	COG1012	belongs to the aldehyde dehydrogenase family
VSVS05_01894	COG1454	alcohol dehydrogenase
VSVS05_01895	COG2095	MarC family integral membrane protein
VSVS05_01896	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VSVS05_01898	COG2186	Transcriptional regulator
VSVS05_01899	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VSVS05_01900	COG1757	Na H antiporter
VSVS05_01904	COG3082	Protein of unknown function (DUF1414)
VSVS05_01905	COG3083	sulfuric ester hydrolase activity
VSVS05_01908	COG2964	Protein conserved in bacteria
VSVS05_01909	COG0251	oxidation-reduction process
VSVS05_01911	COG0446	pyridine nucleotide-disulphide oxidoreductase
VSVS05_01913	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VSVS05_01915	COG3037	sugar-specific permease SgaT UlaA
VSVS05_01917	COG3958	Transketolase
VSVS05_01918	COG2188	Transcriptional regulator
VSVS05_01920	COG0626	cystathionine gamma-synthase activity
VSVS05_01922	COG2199	diguanylate cyclase activity
VSVS05_01923	COG0123	including yeast histone deacetylase and acetoin utilization protein
VSVS05_01925	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VSVS05_01926	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VSVS05_01930	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VSVS05_01931	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VSVS05_01933	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VSVS05_01935	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
VSVS05_01938	COG0356	it plays a direct role in the translocation of protons across the membrane
VSVS05_01941	COG2982	Protein involved in outer membrane biogenesis
VSVS05_01942	COG0572	uridine kinase
VSVS05_01943	COG0489	protein tyrosine kinase activity
VSVS05_01944	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VSVS05_01944	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VSVS05_01948	COG0517	IMP dehydrogenase activity
VSVS05_01948	COG0516	GMP reductase activity
VSVS05_01949	COG0314	molybdopterin synthase activity
VSVS05_01950	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VSVS05_01951	COG0315	cyclic pyranopterin monophosphate synthase activity
VSVS05_01952	COG0521	Mo-molybdopterin cofactor biosynthetic process
VSVS05_01953	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VSVS05_01954	COG0391	Required for morphogenesis under gluconeogenic growth conditions
VSVS05_01956	COG2204	response regulator
VSVS05_01957	COG0556	nucleotide-excision repair
VSVS05_01959	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VSVS05_01960	COG4657	Part of a membrane complex involved in electron transport
VSVS05_01961	COG2878	Part of a membrane complex involved in electron transport
VSVS05_01962	COG4656	Part of a membrane complex involved in electron transport
VSVS05_01963	COG4658	electron transport chain
VSVS05_01966	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VSVS05_01967	COG0346	lactoylglutathione lyase activity
VSVS05_01968	COG3385	transposase activity
VSVS05_01972	COG2056	Na+-H+ antiporter family
VSVS05_01974	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VSVS05_01976	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VSVS05_01980	COG4783	chaperone-mediated protein folding
VSVS05_01981	COG1393	Belongs to the ArsC family
VSVS05_01986	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
VSVS05_01989	COG2912	Transglutaminase-like superfamily
VSVS05_01990	COG3094	Invasion gene expression up-regulator, SirB
VSVS05_01991	COG2890	protein-(glutamine-N5) methyltransferase activity
VSVS05_01992	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
VSVS05_01994	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
VSVS05_01996	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VSVS05_01998	COG0012	GTP binding
VSVS05_02015	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VSVS05_02017	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VSVS05_02019	COG1705	Flagellar rod assembly protein muramidase FlgJ
VSVS05_02019	COG3951	Flagellar rod assembly protein muramidase FlgJ
VSVS05_02021	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VSVS05_02022	COG4786	Flagellar basal body rod
VSVS05_02023	COG4787	bacterial-type flagellum-dependent cell motility
VSVS05_02024	COG1749	Flagellar hook protein flgE
VSVS05_02025	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
VSVS05_02026	COG1558	bacterial-type flagellum-dependent cell motility
VSVS05_02027	COG1815	bacterial-type flagellum-dependent cell motility
VSVS05_02028	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VSVS05_02029	COG0835	chemotaxis
VSVS05_02029	COG0784	Response regulator, receiver
VSVS05_02031	COG2747	anti-sigma28 factor FlgM
VSVS05_02038	COG2885	chlorophyll binding
VSVS05_02039	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VSVS05_02042	COG2608	mercury ion transmembrane transporter activity
VSVS05_02042	COG2217	Heavy metal translocating P-type atpase
VSVS05_02045	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VSVS05_02047	COG0326	Molecular chaperone. Has ATPase activity
VSVS05_02048	COG3710	Transcriptional regulator
VSVS05_02052	COG0622	Phosphoesterase
VSVS05_02057	COG1090	epimerase
VSVS05_02058	COG0300	oxidoreductase activity
VSVS05_02059	COG3118	belongs to the thioredoxin family
VSVS05_02060	COG0330	HflC and HflK could
VSVS05_02061	COG1585	Membrane protein implicated in regulation of membrane protease activity
VSVS05_02066	COG3115	cell septum assembly
VSVS05_02067	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
VSVS05_02068	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VSVS05_02069	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VSVS05_02071	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
VSVS05_02072	COG2190	(PTS) system
VSVS05_02073	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VSVS05_02074	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VSVS05_02075	COG1702	phosphate starvation-inducible protein PhoH
VSVS05_02077	COG4535	Mg2 and Co2 transporter CorC
VSVS05_02078	COG0815	Transfers the fatty acyl group on membrane lipoproteins
VSVS05_02079	COG2888	peptidyl-tyrosine sulfation
VSVS05_02081	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
VSVS05_02082	COG1466	dna polymerase III delta subunit
VSVS05_02083	COG0799	negative regulation of ribosome biogenesis
VSVS05_02085	COG0768	penicillin binding
VSVS05_02086	COG0772	Belongs to the SEDS family
VSVS05_02087	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VSVS05_02088	COG1686	Belongs to the peptidase S11 family
VSVS05_02093	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VSVS05_02095	COG0366	Alpha amylase catalytic
VSVS05_02096	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VSVS05_02096	COG1263	PTS System
VSVS05_02097	COG1609	Transcriptional regulator
VSVS05_02099	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VSVS05_02101	COG2011	ABC-type metal ion transport system permease component
VSVS05_02102	COG1464	Belongs to the NlpA lipoprotein family
VSVS05_02105	COG1720	tRNA m6t6A37 methyltransferase activity
VSVS05_02108	COG0121	glutamine amidotransferase
VSVS05_02109	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VSVS05_02110	COG1960	acyl-CoA dehydrogenase activity
VSVS05_02112	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VSVS05_02114	COG2226	methyltransferase
VSVS05_02116	COG0741	lytic transglycosylase activity
VSVS05_02116	COG1388	LysM domain
VSVS05_02119	COG0347	Belongs to the P(II) protein family
VSVS05_02121	COG0825	malonyl-CoA metabolic process
VSVS05_02122	COG0587	DNA-directed DNA polymerase activity
VSVS05_02127	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VSVS05_02128	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
VSVS05_02130	COG0750	zinc metalloprotease
VSVS05_02132	COG0575	Belongs to the CDS family
VSVS05_02133	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
VSVS05_02135	COG0528	UMP kinase activity
VSVS05_02138	COG0024	Methionine aminopeptidase
VSVS05_02141	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VSVS05_02147	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VSVS05_02147	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VSVS05_02149	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
VSVS05_02154	COG2252	PERMEase
VSVS05_02155	COG2195	Cleaves the N-terminal amino acid of tripeptides
VSVS05_02156	COG4067	protein conserved in archaea
VSVS05_02156	COG0189	ligase activity
VSVS05_02157	COG0189	ligase activity
VSVS05_02159	COG3385	transposase activity
VSVS05_02160	COG0733	neurotransmitter:sodium symporter activity
VSVS05_02162	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VSVS05_02163	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
VSVS05_02164	COG3706	GGDEF domain
VSVS05_02164	COG0745	RESPONSE REGULATOR receiver
VSVS05_02166	COG1477	protein flavinylation
VSVS05_02168	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VSVS05_02169	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VSVS05_02172	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VSVS05_02173	COG0271	Belongs to the BolA IbaG family
VSVS05_02176	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VSVS05_02177	COG2211	Major facilitator Superfamily
VSVS05_02179	COG1595	DNA-templated transcription, initiation
VSVS05_02181	COG3248	Nucleoside-binding outer membrane protein
VSVS05_02182	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VSVS05_02183	COG0693	protein deglycase activity
VSVS05_02184	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VSVS05_02187	COG2975	iron-sulfur cluster assembly
VSVS05_02188	COG0633	Ferredoxin
VSVS05_02190	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VSVS05_02191	COG0316	Belongs to the HesB IscA family
VSVS05_02192	COG0822	iron-sulfur transferase activity
VSVS05_02193	COG1104	cysteine desulfurase activity
VSVS05_02195	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
VSVS05_02196	COG0483	inositol monophosphate 1-phosphatase activity
VSVS05_02205	COG0542	response to heat
VSVS05_02207	COG0564	pseudouridine synthase activity
VSVS05_02208	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VSVS05_02209	COG0741	lytic transglycosylase activity
VSVS05_02210	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VSVS05_02211	COG0077	Prephenate dehydratase
VSVS05_02211	COG1605	Chorismate mutase
VSVS05_02212	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VSVS05_02213	COG5001	Diguanylate cyclase
VSVS05_02214	COG5001	Diguanylate cyclase
VSVS05_02215	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
VSVS05_02218	COG0488	(ABC) transporter
VSVS05_02220	COG0739	heme binding
VSVS05_02221	COG0287	Prephenate dehydrogenase
VSVS05_02221	COG1605	Chorismate mutase
VSVS05_02222	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VSVS05_02223	COG3275	phosphorelay sensor kinase activity
VSVS05_02224	COG3279	Response regulator of the LytR AlgR family
VSVS05_02226	COG1472	Belongs to the glycosyl hydrolase 3 family
VSVS05_02227	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VSVS05_02229	COG1966	Carbon starvation protein
VSVS05_02230	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VSVS05_02231	COG1047	Peptidyl-prolyl cis-trans
VSVS05_02234	COG0196	riboflavin kinase activity
VSVS05_02235	COG0728	peptidoglycan biosynthetic process
VSVS05_02236	COG0268	Binds directly to 16S ribosomal RNA
VSVS05_02237	COG0640	Transcriptional regulator
VSVS05_02238	COG0583	DNA-binding transcription factor activity
VSVS05_02239	COG1283	sodium-dependent phosphate transmembrane transporter activity
VSVS05_02240	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
VSVS05_02245	COG3066	DNA modification
VSVS05_02247	COG0667	Aldo Keto reductase
VSVS05_02251	COG5002	protein histidine kinase activity
VSVS05_02251	COG0784	Response regulator, receiver
VSVS05_02251	COG2198	Histidine kinase
VSVS05_02252	COG2203	Gaf domain
VSVS05_02252	COG3706	GGDEF domain
VSVS05_02252	COG4251	negative regulation of phosphorylation
VSVS05_02252	COG5001	Diguanylate cyclase
VSVS05_02253	COG1242	4 iron, 4 sulfur cluster binding
VSVS05_02254	COG0069	glutamate synthase activity
VSVS05_02254	COG0070	glutamate synthase
VSVS05_02254	COG0067	glutamate synthase
VSVS05_02261	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
VSVS05_02263	COG0195	Participates in both transcription termination and antitermination
VSVS05_02264	COG0779	Required for maturation of 30S ribosomal subunits
VSVS05_02267	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VSVS05_02268	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VSVS05_02269	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
VSVS05_02270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VSVS05_02271	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
VSVS05_02272	COG1534	Rna-binding protein
VSVS05_02273	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VSVS05_02274	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VSVS05_02275	COG2027	D-alanyl-D-alanine carboxypeptidase
VSVS05_02277	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VSVS05_02278	COG0739	heme binding
VSVS05_02281	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VSVS05_02284	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
VSVS05_02285	COG0628	permease
VSVS05_02286	COG2813	Specifically methylates the guanine in position
VSVS05_02287	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VSVS05_02287	COG0784	Response regulator, receiver
VSVS05_02287	COG2198	Histidine kinase
VSVS05_02287	COG2205	protein histidine kinase activity
VSVS05_02288	COG0747	negative chemotaxis
VSVS05_02290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VSVS05_02291	COG0444	Belongs to the ABC transporter superfamily
VSVS05_02292	COG4608	Belongs to the ABC transporter superfamily
VSVS05_02294	COG2971	BadF BadG BcrA BcrD
VSVS05_02297	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VSVS05_02298	COG0693	protein deglycase activity
VSVS05_02300	COG3842	ATPase activity
VSVS05_02301	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
VSVS05_02302	COG1840	ABC-type Fe3 transport system, periplasmic component
VSVS05_02303	COG0004	ammonium transporteR
VSVS05_02306	COG3835	regulator
VSVS05_02307	COG2610	gluconate transmembrane transporter activity
VSVS05_02308	COG1929	Belongs to the glycerate kinase type-1 family
VSVS05_02309	COG1049	propionate catabolic process, 2-methylcitrate cycle
VSVS05_02310	COG1752	Esterase of the alpha-beta hydrolase superfamily
VSVS05_02311	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VSVS05_02312	COG1643	Atp-dependent helicase
VSVS05_02314	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
VSVS05_02315	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VSVS05_02316	COG0617	tRNA 3'-terminal CCA addition
VSVS05_02317	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VSVS05_02318	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
VSVS05_02320	COG0842	Transport permease protein
VSVS05_02321	COG1131	(ABC) transporter
VSVS05_02322	COG0659	secondary active sulfate transmembrane transporter activity
VSVS05_02323	COG0288	reversible hydration of carbon dioxide
VSVS05_02326	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VSVS05_02327	COG0508	dehydrogenase complex catalyzes the overall conversion of
VSVS05_02328	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VSVS05_02329	COG2186	Transcriptional regulator
VSVS05_02330	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VSVS05_02331	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VSVS05_02333	COG0716	FMN binding
VSVS05_02337	COG0795	lipopolysaccharide-transporting ATPase activity
VSVS05_02338	COG0795	lipopolysaccharide-transporting ATPase activity
VSVS05_02340	COG2927	DNA polymerase III (CHI subunit)
VSVS05_02341	COG0525	valine-tRNA ligase activity
VSVS05_02342	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VSVS05_02343	COG0564	pseudouridine synthase activity
VSVS05_02344	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VSVS05_02345	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
VSVS05_02348	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
VSVS05_02349	COG0251	oxidation-reduction process
VSVS05_02350	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VSVS05_02351	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
VSVS05_02352	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VSVS05_02353	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
VSVS05_02356	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
VSVS05_02358	COG3610	response to peptide
VSVS05_02359	COG2966	Psort location CytoplasmicMembrane, score
VSVS05_02360	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VSVS05_02362	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VSVS05_02363	COG0142	geranyltranstransferase activity
VSVS05_02369	COG0589	response to stress
VSVS05_02379	COG0312	modulator of DNA gyrase
VSVS05_02380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VSVS05_02382	COG1530	ribonuclease E activity
VSVS05_02383	COG0424	maF-like protein
VSVS05_02384	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
VSVS05_02385	COG1792	Involved in formation and maintenance of cell shape
VSVS05_02386	COG1077	Cell shape determining protein MreB Mrl
VSVS05_02388	COG3335	DDE superfamily endonuclease
VSVS05_02397	COG1459	type II secretion system
VSVS05_02398	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VSVS05_02400	COG3409	Peptidoglycan-binding domain 1 protein
VSVS05_02400	COG3267	Type II secretory pathway component ExeA
VSVS05_02405	COG2199	diguanylate cyclase activity
VSVS05_02405	COG2200	EAL domain
VSVS05_02406	COG0629	single-stranded DNA binding
VSVS05_02409	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VSVS05_02411	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VSVS05_02412	COG0527	aspartate kinase activity
VSVS05_02415	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
VSVS05_02416	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
VSVS05_02417	COG0762	integral membrane protein
VSVS05_02418	COG1872	DUF167
VSVS05_02421	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VSVS05_02422	COG2066	Belongs to the glutaminase family
VSVS05_02423	COG0220	tRNA (guanine-N7-)-methyltransferase activity
VSVS05_02425	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
VSVS05_02426	COG0741	lytic transglycosylase activity
VSVS05_02431	COG0840	transmembrane signaling receptor activity
VSVS05_02438	COG0204	Acyl-transferase
VSVS05_02440	COG5007	Belongs to the BolA IbaG family
VSVS05_02442	COG2854	intermembrane phospholipid transfer
VSVS05_02443	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VSVS05_02444	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VSVS05_02445	COG1127	ABC transporter
VSVS05_02447	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
VSVS05_02447	COG0517	IMP dehydrogenase activity
VSVS05_02448	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
VSVS05_02450	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VSVS05_02451	COG1137	ATPase activity
VSVS05_02453	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VSVS05_02454	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VSVS05_02456	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VSVS05_02457	COG2239	Acts as a magnesium transporter
VSVS05_02458	COG1410	methionine synthase
VSVS05_02458	COG0646	methionine synthase
VSVS05_02473	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VSVS05_02478	COG0735	belongs to the Fur family
VSVS05_02480	COG0529	Catalyzes the synthesis of activated sulfate
VSVS05_02481	COG0471	metal ion transport
VSVS05_02481	COG3273	potassium ion transport
VSVS05_02484	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VSVS05_02484	COG1648	precorrin-2 dehydrogenase activity
VSVS05_02485	COG0737	Belongs to the 5'-nucleotidase family
VSVS05_02487	COG2153	protein acetylation
VSVS05_02488	COG0697	spore germination
VSVS05_02490	COG0545	Peptidyl-prolyl cis-trans isomerase
VSVS05_02492	COG0203	ribosomal protein L17
VSVS05_02495	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VSVS05_02498	COG0201	protein transport
VSVS05_02499	COG0200	Binds to the 23S rRNA
VSVS05_02500	COG1841	ribosomal large subunit assembly
VSVS05_02502	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
VSVS05_02503	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
VSVS05_02506	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VSVS05_02507	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
VSVS05_02512	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
VSVS05_02513	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
VSVS05_02518	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
VSVS05_02519	COG0051	transcription antitermination factor activity, RNA binding
VSVS05_02520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VSVS05_02521	COG0557	exoribonuclease II activity
VSVS05_02522	COG0402	S-adenosylhomocysteine deaminase activity
VSVS05_02523	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
VSVS05_02524	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VSVS05_02525	COG1446	asparaginase
VSVS05_02526	COG1047	Peptidyl-prolyl cis-trans
VSVS05_02527	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
VSVS05_02529	COG2249	NAD(P)H dehydrogenase (quinone) activity
VSVS05_02530	COG0488	(ABC) transporter
VSVS05_02532	COG0429	hydrolase of the alpha beta-hydrolase fold
VSVS05_02533	COG3089	Belongs to the UPF0270 family
VSVS05_02534	COG3954	Phosphoribulokinase
VSVS05_02538	COG1012	belongs to the aldehyde dehydrogenase family
VSVS05_02539	COG3138	arginine N-succinyltransferase
VSVS05_02540	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VSVS05_02544	COG0546	phosphoglycolate phosphatase activity
VSVS05_02545	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VSVS05_02546	COG0338	D12 class N6 adenine-specific DNA methyltransferase
VSVS05_02555	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
VSVS05_02557	COG0678	peroxiredoxin activity
VSVS05_02557	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VSVS05_02558	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VSVS05_02559	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VSVS05_02559	COG0165	Argininosuccinate lyase
VSVS05_02560	COG0137	argininosuccinate synthase activity
VSVS05_02561	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VSVS05_02562	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
VSVS05_02564	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VSVS05_02566	COG1045	serine acetyltransferase
VSVS05_02568	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
VSVS05_02569	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VSVS05_02571	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
VSVS05_02573	COG1053	succinate dehydrogenase
VSVS05_02574	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VSVS05_02578	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
VSVS05_02582	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VSVS05_02586	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VSVS05_02588	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VSVS05_02590	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VSVS05_02594	COG1086	Polysaccharide biosynthesis protein
VSVS05_02603	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
VSVS05_02605	COG5433	transposase activity
VSVS05_02608	COG1051	belongs to the nudix hydrolase family
VSVS05_02609	COG0250	Participates in transcription elongation, termination and antitermination
VSVS05_02610	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VSVS05_02611	COG1609	Transcriptional regulator
VSVS05_02612	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VSVS05_02614	COG0281	malic enzyme
VSVS05_02617	COG0626	cystathionine gamma-synthase activity
VSVS05_02618	COG0527	aspartate kinase activity
VSVS05_02618	COG0460	homoserine dehydrogenase
VSVS05_02619	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VSVS05_02621	COG1494	fructose-1,6-bisphosphatase
VSVS05_02622	COG3706	GGDEF domain
VSVS05_02623	COG0459	protein refolding
VSVS05_02624	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VSVS05_02627	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VSVS05_02630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VSVS05_02631	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VSVS05_02632	COG1560	Kdo2-lipid A biosynthetic process
VSVS05_02634	COG1519	Transferase
VSVS05_02640	COG3335	DDE superfamily endonuclease
VSVS05_02642	COG1028	Short-chain dehydrogenase reductase Sdr
VSVS05_02643	COG1083	cytidylyl-transferase
VSVS05_02645	COG0673	inositol 2-dehydrogenase activity
VSVS05_02648	COG2089	acid synthase
VSVS05_02649	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VSVS05_02650	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VSVS05_02651	COG1086	Polysaccharide biosynthesis protein
VSVS05_02652	COG3328	transposase activity
VSVS05_02653	COG3328	transposase activity
VSVS05_02654	COG1216	Glycosyl transferase, family 2
VSVS05_02666	COG3083	sulfuric ester hydrolase activity
VSVS05_02668	COG3642	lipopolysaccharide core region biosynthetic process
VSVS05_02669	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VSVS05_02670	COG0859	PFAM glycosyl transferase family 9
VSVS05_02671	COG0463	Glycosyl transferase, family 2
VSVS05_02672	COG0859	PFAM glycosyl transferase family 9
VSVS05_02673	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
VSVS05_02679	COG2003	Belongs to the UPF0758 family
VSVS05_02680	COG0840	transmembrane signaling receptor activity
VSVS05_02681	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
VSVS05_02682	COG1309	transcriptional regulator
VSVS05_02683	COG1560	Kdo2-lipid A biosynthetic process
VSVS05_02686	COG1561	YicC-like family, N-terminal region
VSVS05_02687	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
VSVS05_02689	COG2252	PERMEase
VSVS05_02693	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VSVS05_02694	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VSVS05_02695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VSVS05_02696	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VSVS05_02698	COG1218	3'(2'),5'-bisphosphate nucleotidase
VSVS05_02699	COG0494	nUDIX hydrolase
VSVS05_02700	COG0316	Belongs to the HesB IscA family
VSVS05_02700	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
VSVS05_02701	COG1040	competence protein
VSVS05_02702	COG0596	Alpha beta hydrolase
VSVS05_02704	COG2183	response to ionizing radiation
VSVS05_02705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VSVS05_02706	COG0745	RESPONSE REGULATOR receiver
VSVS05_02707	COG2205	protein histidine kinase activity
VSVS05_02709	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VSVS05_02710	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VSVS05_02711	COG3156	type II secretion system protein K
VSVS05_02712	COG4795	General secretion pathway protein
VSVS05_02713	COG2165	general secretion pathway protein
VSVS05_02714	COG2165	general secretion pathway protein
VSVS05_02715	COG2165	general secretion pathway protein
VSVS05_02716	COG1459	type II secretion system
VSVS05_02717	COG1459	type II secretion system
VSVS05_02718	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VSVS05_02720	COG3031	protein transport across the cell outer membrane
VSVS05_02721	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VSVS05_02722	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
VSVS05_02725	COG0456	acetyltransferase
VSVS05_02731	COG0174	glutamine synthetase
VSVS05_02732	COG3852	Histidine kinase
VSVS05_02733	COG2204	response regulator
VSVS05_02734	COG3300	MHYT domain
VSVS05_02734	COG5001	Diguanylate cyclase
VSVS05_02735	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VSVS05_02743	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
VSVS05_02747	COG0009	L-threonylcarbamoyladenylate synthase
VSVS05_02748	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VSVS05_02752	COG0758	DNA mediated transformation
VSVS05_02754	COG0242	peptide deformylase activity
VSVS05_02756	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VSVS05_02756	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VSVS05_02757	COG0569	domain protein
VSVS05_02758	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VSVS05_02759	COG1272	protein, Hemolysin III
VSVS05_02760	COG4326	sporulation control protein
VSVS05_02761	COG3084	Protein conserved in bacteria
VSVS05_02763	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VSVS05_02764	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VSVS05_02766	COG0606	chelatase, subunit chli
VSVS05_02768	COG3978	acetolactate synthase activity
VSVS05_02769	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VSVS05_02770	COG0129	dihydroxy-acid dehydratase activity
VSVS05_02772	COG0604	alcohol dehydrogenase
VSVS05_02774	COG0425	Belongs to the sulfur carrier protein TusA family
VSVS05_02776	COG0747	negative chemotaxis
VSVS05_02778	COG0751	glycine-tRNA ligase activity
VSVS05_02779	COG3977	Valine--pyruvate aminotransferase
VSVS05_02780	COG0071	Belongs to the small heat shock protein (HSP20) family
VSVS05_02781	COG0187	DNA topoisomerase II activity
VSVS05_02784	COG0592	DNA-directed DNA polymerase activity
VSVS05_02788	COG1126	abc transporter atp-binding protein
VSVS05_02791	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
VSVS05_02793	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
VSVS05_02794	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VSVS05_02795	COG0445	tRNA wobble uridine modification
VSVS05_02796	COG1192	Involved in chromosome partitioning
VSVS05_02797	COG1475	DNA binding
VSVS05_02798	COG3312	ion transport
VSVS05_02801	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
VSVS05_02802	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
VSVS05_02803	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
VSVS05_02804	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VSVS05_02806	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VSVS05_02808	COG2814	Major facilitator Superfamily
VSVS05_02809	COG0583	DNA-binding transcription factor activity
VSVS05_02810	COG0183	Belongs to the thiolase family
VSVS05_02812	COG1739	Uncharacterized protein family UPF0029
VSVS05_02814	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VSVS05_02830	COG0352	thiamine-phosphate diphosphorylase activity
VSVS05_02831	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VSVS05_02832	COG2104	thiamine diphosphate biosynthetic process
VSVS05_02834	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VSVS05_02835	COG0006	proline dipeptidase activity
VSVS05_02835	COG0006	proline dipeptidase activity
VSVS05_02839	COG1522	sequence-specific DNA binding
VSVS05_02840	COG5002	protein histidine kinase activity
VSVS05_02840	COG5001	Diguanylate cyclase
VSVS05_02841	COG0742	ribosomal rna small subunit methyltransferase
VSVS05_02842	COG0697	spore germination
VSVS05_02843	COG0589	response to stress
VSVS05_02844	COG1528	Iron-storage protein
VSVS05_02846	COG2081	HI0933 family
VSVS05_02847	COG1609	Transcriptional regulator
VSVS05_02848	COG0129	dihydroxy-acid dehydratase activity
VSVS05_02849	COG3265	gluconokinase activity
VSVS05_02850	COG2610	gluconate transmembrane transporter activity
VSVS05_02851	COG0800	Aldolase
VSVS05_02853	COG1322	Protein conserved in bacteria
VSVS05_02856	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
VSVS05_02859	COG0805	protein transport
VSVS05_02860	COG0084	hydrolase, TatD family'
VSVS05_02862	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VSVS05_02862	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VSVS05_02863	COG0218	Necessary for normal cell division and for the maintenance of normal septation
VSVS05_02868	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VSVS05_02869	COG0583	DNA-binding transcription factor activity
VSVS05_02871	COG2960	long-chain fatty acid transporting porin activity
VSVS05_02872	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VSVS05_02873	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VSVS05_02874	COG1309	transcriptional regulator
VSVS05_02883	COG0747	negative chemotaxis
VSVS05_02885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VSVS05_02886	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VSVS05_02887	COG2194	sulfuric ester hydrolase activity
VSVS05_02894	COG0840	transmembrane signaling receptor activity
VSVS05_02895	COG0251	oxidation-reduction process
VSVS05_02896	COG0626	cystathionine gamma-synthase activity
VSVS05_02897	COG1301	dicarboxylic acid transport
VSVS05_02900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VSVS05_02901	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VSVS05_02902	COG0339	signal peptide processing
VSVS05_02905	COG3220	belongs to the UPF0276 family
VSVS05_02907	COG0210	DNA helicase
VSVS05_02908	COG1280	lysine exporter protein (LysE YggA)
VSVS05_02910	COG2962	Rard protein
VSVS05_02911	COG0514	ATP-dependent DNA helicase (RecQ)
VSVS05_02913	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
VSVS05_02914	COG0248	Ppx GppA phosphatase
VSVS05_02916	COG3118	belongs to the thioredoxin family
VSVS05_02917	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
VSVS05_02919	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
VSVS05_02929	COG3071	HemY protein
VSVS05_02930	COG2959	enzyme of heme biosynthesis
VSVS05_02931	COG1587	Uroporphyrinogen-III synthase
VSVS05_02933	COG3072	Adenylate cyclase
VSVS05_02934	COG1965	Belongs to the frataxin family
VSVS05_02935	COG0019	diaminopimelate decarboxylase activity
VSVS05_02938	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
VSVS05_02939	COG1011	Hydrolase
VSVS05_02942	COG0561	phosphatase activity
VSVS05_02943	COG2267	carboxylic ester hydrolase activity
VSVS05_02944	COG1280	lysine exporter protein (LysE YggA)
VSVS05_02945	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VSVS05_02946	COG0640	Transcriptional regulator
VSVS05_02947	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VSVS05_02955	COG2095	MarC family integral membrane protein
VSVS05_02957	COG0742	ribosomal rna small subunit methyltransferase
VSVS05_02958	COG0552	protein localization to endoplasmic reticulum
VSVS05_02959	COG2884	Cell division ATP-binding protein ftsE
VSVS05_02960	COG2177	Part of the ABC transporter FtsEX involved in
VSVS05_02962	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VSVS05_02963	COG0705	Rhomboid family
VSVS05_02964	COG1580	Controls the rotational direction of flagella during chemotaxis
VSVS05_02965	COG3161	chorismate lyase activity
VSVS05_02967	COG2937	Belongs to the GPAT DAPAT family
VSVS05_02968	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VSVS05_02969	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VSVS05_02971	COG0534	Mate efflux family protein
VSVS05_02973	COG1309	transcriptional regulator
VSVS05_02975	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VSVS05_02978	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
VSVS05_02982	COG5002	protein histidine kinase activity
VSVS05_02982	COG0784	Response regulator, receiver
VSVS05_02982	COG2205	protein histidine kinase activity
VSVS05_02984	COG0402	S-adenosylhomocysteine deaminase activity
VSVS05_02985	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
VSVS05_02986	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
VSVS05_02988	COG3217	Mosc domain protein beta barrel domain protein
VSVS05_02988	COG0633	Ferredoxin
VSVS05_02988	COG3217	Mosc domain protein beta barrel domain protein
VSVS05_02988	COG0633	Ferredoxin
VSVS05_02989	COG0697	spore germination
VSVS05_02994	COG0366	Alpha amylase catalytic
VSVS05_03002	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
VSVS05_03002	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
VSVS05_03003	COG0516	GMP reductase activity
VSVS05_03006	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VSVS05_03008	COG3437	response regulator, receiver
VSVS05_03009	COG3290	protein histidine kinase activity
VSVS05_03010	COG4565	transcriptional regulatory protein
VSVS05_03016	COG1028	Short-chain dehydrogenase reductase Sdr
VSVS05_03017	COG0471	metal ion transport
VSVS05_03021	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VSVS05_03026	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VSVS05_03030	COG0745	RESPONSE REGULATOR receiver
VSVS05_03031	COG1366	Belongs to the anti-sigma-factor antagonist family
VSVS05_03032	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
VSVS05_03046	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VSVS05_03047	COG3186	Phenylalanine-4-hydroxylase
VSVS05_03051	COG1011	Hydrolase
VSVS05_03052	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VSVS05_03053	COG2146	nitrite reductase [NAD(P)H] activity
VSVS05_03055	COG1648	precorrin-2 dehydrogenase activity
VSVS05_03055	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VSVS05_03056	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VSVS05_03056	COG2199	diguanylate cyclase activity
VSVS05_03062	COG1760	l-serine dehydratase
VSVS05_03065	COG3706	GGDEF domain
VSVS05_03066	COG0835	chemotaxis
VSVS05_03066	COG0784	Response regulator, receiver
VSVS05_03067	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VSVS05_03068	COG1560	Kdo2-lipid A biosynthetic process
VSVS05_03070	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
VSVS05_03073	COG2425	protein containing a von Willebrand factor type A (vWA) domain
VSVS05_03075	COG1846	Transcriptional regulator
VSVS05_03076	COG2315	Protein conserved in bacteria
VSVS05_03089	COG2814	Major facilitator Superfamily
VSVS05_03090	COG3118	belongs to the thioredoxin family
VSVS05_03091	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VSVS05_03093	COG0419	ATPase involved in DNA repair
VSVS05_03094	COG0784	Response regulator, receiver
VSVS05_03094	COG2205	protein histidine kinase activity
VSVS05_03096	COG0038	chloride channel
VSVS05_03097	COG0523	cobalamin synthesis protein
VSVS05_03098	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
VSVS05_03100	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
VSVS05_03101	COG1070	Carbohydrate kinase
VSVS05_03103	COG1070	Carbohydrate kinase
VSVS05_03104	COG0235	Class ii aldolase
VSVS05_03109	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VSVS05_03109	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
VSVS05_03111	COG3716	PTS system mannose fructose sorbose family IID component
VSVS05_03112	COG1349	DNA-binding transcription factor activity
VSVS05_03113	COG3328	transposase activity
VSVS05_03121	COG0328	RNA-DNA hybrid ribonuclease activity
VSVS05_03124	COG2003	Belongs to the UPF0758 family
VSVS05_03126	COG2199	diguanylate cyclase activity
VSVS05_03127	COG0583	DNA-binding transcription factor activity
VSVS05_03128	COG1335	isochorismatase
VSVS05_03131	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
VSVS05_03132	COG1304	FMN binding
VSVS05_03133	COG0549	Belongs to the carbamate kinase family
VSVS05_03135	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
VSVS05_03147	COG0840	transmembrane signaling receptor activity
VSVS05_03149	COG0840	transmembrane signaling receptor activity
VSVS05_03150	COG0835	chemotaxis
VSVS05_03150	COG0784	Response regulator, receiver
VSVS05_03152	COG0840	transmembrane signaling receptor activity
VSVS05_03158	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VSVS05_03159	COG0732	type I restriction modification DNA specificity domain
VSVS05_03160	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
VSVS05_03166	COG0494	nUDIX hydrolase
VSVS05_03168	COG0582	viral genome integration into host DNA
VSVS05_03169	COG1280	lysine exporter protein (LysE YggA)
VSVS05_03172	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VSVS05_03176	COG1620	l-lactate permease
VSVS05_03177	COG0247	lactate metabolic process
VSVS05_03178	COG1139	Iron-sulfur cluster binding protein
VSVS05_03179	COG1556	Lactate utilization protein
VSVS05_03180	COG0583	DNA-binding transcription factor activity
VSVS05_03182	COG2186	Transcriptional regulator
VSVS05_03183	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VSVS05_03184	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VSVS05_03186	COG0246	Mannitol dehydrogenase
VSVS05_03187	COG1904	glucuronate isomerase
VSVS05_03188	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VSVS05_03189	COG0800	Aldolase
VSVS05_03192	COG2731	YhcH YjgK YiaL family protein
VSVS05_03193	COG2113	Glycine betaine
VSVS05_03194	COG4176	ABC-type proline glycine betaine transport system permease component
VSVS05_03195	COG4175	Glycine betaine
VSVS05_03196	COG0456	acetyltransferase
VSVS05_03197	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VSVS05_03198	COG0662	Cupin 2, conserved barrel domain protein
VSVS05_03255	COG3335	DDE superfamily endonuclease
VSVS05_03258	COG2026	Addiction module toxin, RelE StbE family
VSVS05_03270	COG2801	Transposase and inactivated derivatives
VSVS05_03272	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
VSVS05_03274	COG0730	response to heat
VSVS05_03279	COG1418	mRNA catabolic process
VSVS05_03280	COG0653	protein targeting
VSVS05_03284	COG0583	DNA-binding transcription factor activity
VSVS05_03286	COG1067	ATP-dependent peptidase activity
VSVS05_03287	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VSVS05_03288	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
VSVS05_03289	COG4166	transmembrane transport
VSVS05_03290	COG4174	ABC transporter (Permease)
VSVS05_03291	COG4239	(ABC) transporter, permease
VSVS05_03292	COG4172	Belongs to the ABC transporter superfamily
VSVS05_03293	COG3300	MHYT domain
VSVS05_03293	COG5001	Diguanylate cyclase
VSVS05_03295	COG4607	ABC-type enterochelin transport system periplasmic component
VSVS05_03296	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VSVS05_03297	COG4605	iron ion homeostasis
VSVS05_03298	COG4604	ABC transporter, ATP-binding protein
VSVS05_03299	COG0789	Transcriptional regulator
VSVS05_03300	COG2207	Transcriptional regulator
VSVS05_03301	COG4206	TonB-dependent receptor
VSVS05_03302	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VSVS05_03304	COG0514	ATP-dependent DNA helicase (RecQ)
VSVS05_03307	COG0556	nucleotide-excision repair
VSVS05_03309	COG1114	Component of the transport system for branched-chain amino acids
VSVS05_03313	COG0513	Belongs to the DEAD box helicase family
VSVS05_03315	COG0534	Mate efflux family protein
VSVS05_03316	COG1288	antiporter activity
VSVS05_03318	COG0330	HflC and HflK could
VSVS05_03320	COG5001	Diguanylate cyclase
VSVS05_03322	COG0641	radical SAM
VSVS05_03323	COG0583	DNA-binding transcription factor activity
VSVS05_03324	COG3119	arylsulfatase activity
VSVS05_03338	COG3005	denitrification pathway
VSVS05_03342	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VSVS05_03342	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
VSVS05_03343	COG3850	Histidine kinase
VSVS05_03344	COG2197	response regulator
VSVS05_03345	COG3069	C4-dicarboxylate transmembrane transporter activity
VSVS05_03346	COG2200	EAL domain
VSVS05_03349	COG3038	cytochrome b561
VSVS05_03351	COG2116	formate transmembrane transporter activity
VSVS05_03352	COG0583	DNA-binding transcription factor activity
VSVS05_03354	COG3593	DNA synthesis involved in DNA repair
VSVS05_03355	COG0737	Belongs to the 5'-nucleotidase family
VSVS05_03360	COG2824	Alkylphosphonate utilization operon protein PhnA
VSVS05_03361	COG0750	zinc metalloprotease
VSVS05_03363	COG2050	protein possibly involved in aromatic compounds catabolism
VSVS05_03365	COG4533	DNA binding
VSVS05_03367	COG0583	DNA-binding transcription factor activity
VSVS05_03368	COG0045	succinate-CoA ligase (ADP-forming) activity
VSVS05_03368	COG1042	CoA-binding domain protein
VSVS05_03368	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VSVS05_03370	COG1181	Belongs to the D-alanine--D-alanine ligase family
VSVS05_03373	COG0023	Translation Initiation Factor
VSVS05_03379	COG0745	RESPONSE REGULATOR receiver
VSVS05_03382	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
VSVS05_03383	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
VSVS05_03386	COG3706	GGDEF domain
VSVS05_03388	COG3706	GGDEF domain
VSVS05_03388	COG2203	Gaf domain
VSVS05_03388	COG4251	negative regulation of phosphorylation
VSVS05_03388	COG5001	Diguanylate cyclase
VSVS05_03390	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
VSVS05_03391	COG4149	molybdate abc transporter
VSVS05_03392	COG0725	ABC transporter, periplasmic molybdate-binding protein
VSVS05_03393	COG1492	cobalamin metabolic process
VSVS05_03397	COG1609	Transcriptional regulator
VSVS05_03398	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VSVS05_03398	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VSVS05_03399	COG1105	Belongs to the carbohydrate kinase PfkB family
VSVS05_03400	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VSVS05_03400	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VSVS05_03400	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
VSVS05_03402	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VSVS05_03403	COG1979	alcohol dehydrogenase
VSVS05_03406	COG0784	Response regulator, receiver
VSVS05_03406	COG2205	protein histidine kinase activity
VSVS05_03406	COG2198	Histidine kinase
VSVS05_03407	COG1879	ABC-type sugar transport system periplasmic component
VSVS05_03408	COG1803	Methylglyoxal synthase
VSVS05_03409	COG0210	DNA helicase
VSVS05_03410	COG1289	transmembrane transporter activity
VSVS05_03416	COG2827	Endonuclease containing a URI domain
VSVS05_03419	COG2926	Belongs to the UPF0265 family
VSVS05_03424	COG0545	Peptidyl-prolyl cis-trans isomerase
VSVS05_03425	COG4067	protein conserved in archaea
VSVS05_03425	COG0189	ligase activity
VSVS05_03428	COG0602	queuosine metabolic process
VSVS05_03429	COG1328	CTP reductase activity
VSVS05_03434	COG3040	lipid binding
VSVS05_03437	COG0183	Belongs to the thiolase family
VSVS05_03439	COG1309	transcriptional regulator
VSVS05_03440	COG0513	Belongs to the DEAD box helicase family
VSVS05_03441	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
VSVS05_03443	COG0814	amino acid
VSVS05_03445	COG2176	DNA-directed DNA polymerase activity
VSVS05_03446	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VSVS05_03447	COG1846	Transcriptional regulator
VSVS05_03448	COG2814	Major facilitator Superfamily
VSVS05_03451	COG0534	Mate efflux family protein
VSVS05_03457	COG1136	(ABC) transporter
VSVS05_03457	COG0577	efflux transmembrane transporter activity
VSVS05_03469	COG0277	FAD linked oxidase domain protein
VSVS05_03473	COG0513	Belongs to the DEAD box helicase family
VSVS05_03476	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VSVS05_03478	COG2897	thiosulfate sulfurtransferase activity
VSVS05_03482	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VSVS05_03483	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VSVS05_03484	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
VSVS05_03485	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
VSVS05_03486	COG1984	allophanate hydrolase subunit 2
VSVS05_03488	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
VSVS05_03489	COG4181	ATPase activity
VSVS05_03491	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VSVS05_03492	COG5001	Diguanylate cyclase
VSVS05_03492	COG3300	MHYT domain
VSVS05_03498	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VSVS05_03499	COG3437	response regulator, receiver
VSVS05_03499	COG0784	Response regulator, receiver
VSVS05_03502	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VSVS05_03503	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VSVS05_03504	COG0840	transmembrane signaling receptor activity
VSVS05_03505	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
VSVS05_03510	COG0457	Tetratricopeptide repeat
VSVS05_03511	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
VSVS05_03512	COG1215	transferase activity, transferring glycosyl groups
VSVS05_03513	COG1215	transferase activity, transferring glycosyl groups
VSVS05_03517	COG2194	sulfuric ester hydrolase activity
VSVS05_03519	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
VSVS05_03522	COG3706	GGDEF domain
VSVS05_03526	COG3111	PFAM Bacterial OB fold (BOF) protein
VSVS05_03529	COG1629	transport
VSVS05_03530	COG4607	ABC-type enterochelin transport system periplasmic component
VSVS05_03532	COG2814	Major facilitator Superfamily
VSVS05_03537	COG1840	ABC-type Fe3 transport system, periplasmic component
VSVS05_03538	COG2271	Major facilitator Superfamily
VSVS05_03539	COG0469	pyruvate kinase activity
VSVS05_03540	COG2759	Belongs to the formate--tetrahydrofolate ligase family
VSVS05_03541	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VSVS05_03541	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VSVS05_03544	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VSVS05_03545	COG0363	glucosamine-6-phosphate deaminase activity
VSVS05_03546	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
VSVS05_03548	COG3385	transposase activity
VSVS05_03550	COG2095	MarC family integral membrane protein
VSVS05_03554	COG0798	PFAM Bile acid sodium symporter
VSVS05_03555	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VSVS05_03559	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VSVS05_03564	COG0318	PFAM AMP-dependent synthetase and ligase
VSVS05_03570	COG0156	8-amino-7-oxononanoate synthase activity
VSVS05_03574	COG1794	racemase activity, acting on amino acids and derivatives
VSVS05_03586	COG1216	Glycosyl transferase, family 2
VSVS05_03586	COG0463	Glycosyl transferase, family 2
VSVS05_03587	COG0438	transferase activity, transferring glycosyl groups
VSVS05_03589	COG1215	transferase activity, transferring glycosyl groups
VSVS05_03591	COG1596	polysaccharide export
VSVS05_03592	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VSVS05_03593	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VSVS05_03594	COG0581	inorganic phosphate transmembrane transporter activity
VSVS05_03595	COG0573	inorganic phosphate transmembrane transporter activity
VSVS05_03596	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VSVS05_03597	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VSVS05_03598	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VSVS05_03598	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VSVS05_03598	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VSVS05_03599	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VSVS05_03601	COG2207	Transcriptional regulator
VSVS05_03602	COG1482	cell wall glycoprotein biosynthetic process
VSVS05_03603	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VSVS05_03603	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VSVS05_03603	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VSVS05_03604	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VSVS05_03605	COG3708	Transcriptional regulator
VSVS05_03605	COG2207	Transcriptional regulator
VSVS05_03611	COG0579	oxidoreductase
VSVS05_03613	COG0714	Associated with various cellular activities
VSVS05_03616	COG2304	oxidoreductase activity
VSVS05_03617	COG2304	oxidoreductase activity
VSVS05_03620	COG3706	GGDEF domain
VSVS05_03622	COG1765	OsmC-like protein
VSVS05_03623	COG0673	inositol 2-dehydrogenase activity
VSVS05_03627	COG0531	amino acid
VSVS05_03630	COG1566	PFAM secretion protein HlyD family protein
VSVS05_03632	COG1012	belongs to the aldehyde dehydrogenase family
VSVS05_03637	COG3385	transposase activity
VSVS05_03639	COG2190	(PTS) system
VSVS05_03639	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VSVS05_03639	COG1263	PTS System
VSVS05_03644	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VSVS05_03645	COG1349	DNA-binding transcription factor activity
VSVS05_03647	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VSVS05_03653	COG1501	Belongs to the glycosyl hydrolase 31 family
VSVS05_03654	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VSVS05_03656	COG0583	DNA-binding transcription factor activity
VSVS05_03660	COG3385	transposase activity
VSVS05_03662	COG1609	Transcriptional regulator
VSVS05_03663	COG1621	beta-fructofuranosidase activity
VSVS05_03664	COG1263	PTS System
VSVS05_03664	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VSVS05_03665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VSVS05_03666	COG0784	Response regulator, receiver
VSVS05_03666	COG2205	protein histidine kinase activity
VSVS05_03668	COG1757	Na H antiporter
VSVS05_03680	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VSVS05_03684	COG2963	transposase activity
VSVS05_03685	COG2801	Transposase and inactivated derivatives
VSVS05_03691	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VSVS05_03693	COG1309	transcriptional regulator
VSVS05_03696	COG4989	oxidoreductase activity
VSVS05_03697	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VSVS05_03700	COG1612	heme a metabolic process
VSVS05_03704	COG1845	cytochrome c oxidase, subunit III
VSVS05_03705	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
VSVS05_03706	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
VSVS05_03707	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
VSVS05_03709	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VSVS05_03710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VSVS05_03712	COG1280	lysine exporter protein (LysE YggA)
VSVS05_03721	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VSVS05_03722	COG1278	Cold shock
VSVS05_03724	COG4667	esterase of the alpha-beta hydrolase superfamily
VSVS05_03728	COG2199	diguanylate cyclase activity
VSVS05_03732	COG3530	Putative quorum-sensing-regulated virulence factor
VSVS05_03735	COG1686	Belongs to the peptidase S11 family
VSVS05_03737	COG1278	Cold shock
VSVS05_03740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VSVS05_03740	COG1017	nitric oxide dioxygenase activity
VSVS05_03741	COG3604	Transcriptional regulator
VSVS05_03743	COG0546	phosphoglycolate phosphatase activity
VSVS05_03744	COG2249	NAD(P)H dehydrogenase (quinone) activity
VSVS05_03748	COG0697	spore germination
VSVS05_03751	COG2814	Major facilitator Superfamily
VSVS05_03752	COG0583	DNA-binding transcription factor activity
VSVS05_03753	COG5001	Diguanylate cyclase
VSVS05_03757	COG2197	response regulator
VSVS05_03761	COG0509	glycine decarboxylation via glycine cleavage system
VSVS05_03762	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VSVS05_03762	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VSVS05_03769	COG3122	Protein conserved in bacteria
VSVS05_03774	COG0291	Belongs to the bacterial ribosomal protein bL35 family
VSVS05_03775	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
VSVS05_03778	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VSVS05_03782	COG0583	DNA-binding transcription factor activity
VSVS05_03783	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
VSVS05_03787	COG0564	pseudouridine synthase activity
VSVS05_03788	COG0110	maltose O-acetyltransferase activity
VSVS05_03789	COG1902	pentaerythritol trinitrate reductase activity
VSVS05_03789	COG0446	pyridine nucleotide-disulphide oxidoreductase
VSVS05_03793	COG0488	(ABC) transporter
VSVS05_03794	COG0529	Catalyzes the synthesis of activated sulfate
VSVS05_03795	COG4667	esterase of the alpha-beta hydrolase superfamily
VSVS05_03798	COG0745	RESPONSE REGULATOR receiver
VSVS05_03800	COG1653	transport
VSVS05_03804	COG3706	GGDEF domain
VSVS05_03813	COG0561	phosphatase activity
VSVS05_03815	COG2211	Major facilitator Superfamily
VSVS05_03816	COG0366	Alpha amylase catalytic
VSVS05_03820	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VSVS05_03821	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VSVS05_03823	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VSVS05_03830	COG3706	GGDEF domain
VSVS05_03831	COG0786	glutamate:sodium symporter activity
VSVS05_03832	COG4628	conserved protein (DUF2132)
VSVS05_03833	COG0488	(ABC) transporter
VSVS05_03839	COG1053	succinate dehydrogenase
VSVS05_03839	COG3976	FMN-binding domain protein
VSVS05_03846	COG2814	Major facilitator Superfamily
VSVS05_03850	COG0583	DNA-binding transcription factor activity
VSVS05_03859	COG3842	ATPase activity
VSVS05_03862	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VSVS05_03863	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VSVS05_03863	COG2207	Transcriptional regulator
VSVS05_03864	COG4772	TonB-dependent receptor
VSVS05_03869	COG3681	Belongs to the UPF0597 family
VSVS05_03873	COG1881	PFAM PEBP family protein
VSVS05_03877	COG2860	membrane
VSVS05_03878	COG3335	DDE superfamily endonuclease
VSVS05_03879	COG0076	glutamate decarboxylase activity
VSVS05_03881	COG0531	amino acid
VSVS05_03882	COG0513	Belongs to the DEAD box helicase family
VSVS05_03883	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VSVS05_03884	COG0583	DNA-binding transcription factor activity
VSVS05_03886	COG1982	Orn Lys Arg decarboxylase major
VSVS05_03887	COG0531	amino acid
VSVS05_03889	COG4533	DNA binding
VSVS05_03891	COG4176	ABC-type proline glycine betaine transport system permease component
VSVS05_03892	COG4175	Glycine betaine
VSVS05_03892	COG3448	diguanylate cyclase activity
VSVS05_03905	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VSVS05_03905	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VSVS05_03905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VSVS05_03907	COG0383	alpha-mannosidase activity
VSVS05_03908	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
VSVS05_03908	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VSVS05_03908	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VSVS05_03909	COG1737	Transcriptional regulator
VSVS05_03914	COG2226	methyltransferase
VSVS05_03916	COG0583	DNA-binding transcription factor activity
VSVS05_03917	COG2188	Transcriptional regulator
VSVS05_03919	COG1735	metal-dependent hydrolase with the TIM-barrel fold
VSVS05_03922	COG3457	Alanine racemase
VSVS05_03923	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
VSVS05_03925	COG2258	MOSC domain
VSVS05_03927	COG1342	Belongs to the UPF0251 family
VSVS05_03930	COG2176	DNA-directed DNA polymerase activity
VSVS05_03931	COG0840	transmembrane signaling receptor activity
VSVS05_03937	COG1595	DNA-templated transcription, initiation
VSVS05_03943	COG0456	acetyltransferase
VSVS05_03945	COG1609	Transcriptional regulator
VSVS05_03949	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VSVS05_03950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VSVS05_03951	COG0800	Aldolase
VSVS05_03952	COG2731	YhcH YjgK YiaL family protein
VSVS05_03954	COG0351	phosphomethylpyrimidine kinase
VSVS05_03955	COG0583	DNA-binding transcription factor activity
VSVS05_03959	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
VSVS05_03972	COG4589	Belongs to the CDS family
VSVS05_03978	COG0494	nUDIX hydrolase
VSVS05_03979	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VSVS05_03984	COG3755	Protein conserved in bacteria
VSVS05_03992	COG1882	Formate acetyltransferase
VSVS05_03993	COG3706	GGDEF domain
VSVS05_03993	COG0745	RESPONSE REGULATOR receiver
VSVS05_03995	COG1444	tRNA N-acetyltransferase activity
VSVS05_04000	COG4608	Belongs to the ABC transporter superfamily
VSVS05_04001	COG0444	Belongs to the ABC transporter superfamily
VSVS05_04004	COG0217	transcriptional regulatory protein
VSVS05_04011	COG3152	Membrane
VSVS05_04022	COG0561	phosphatase activity
VSVS05_04024	COG1454	alcohol dehydrogenase
VSVS05_04025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VSVS05_04026	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
VSVS05_04027	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VSVS05_04028	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
VSVS05_04029	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VSVS05_04030	COG1263	PTS System
VSVS05_04030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VSVS05_04032	COG0814	amino acid
VSVS05_04033	COG0814	amino acid
VSVS05_04034	COG0753	catalase activity
VSVS05_04039	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VSVS05_04040	COG1940	carbohydrate kinase activity
VSVS05_04041	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
VSVS05_04042	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VSVS05_04043	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VSVS05_04044	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VSVS05_04045	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VSVS05_04046	COG1737	Transcriptional regulator
VSVS05_04047	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
VSVS05_04048	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
VSVS05_04049	COG0583	DNA-binding transcription factor activity
VSVS05_04053	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
VSVS05_04054	COG0372	Belongs to the citrate synthase family
VSVS05_04060	COG4628	conserved protein (DUF2132)
VSVS05_04061	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VSVS05_04067	COG2824	Alkylphosphonate utilization operon protein PhnA
VSVS05_04073	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
VSVS05_04076	COG0583	DNA-binding transcription factor activity
VSVS05_04078	COG4106	trans-aconitate 2-methyltransferase activity
VSVS05_04080	COG1858	cytochrome C peroxidase
VSVS05_04083	COG1129	ABC transporter
VSVS05_04084	COG1172	Belongs to the binding-protein-dependent transport system permease family
VSVS05_04085	COG3335	DDE superfamily endonuclease
VSVS05_04086	COG1172	Belongs to the binding-protein-dependent transport system permease family
VSVS05_04087	COG1172	Belongs to the binding-protein-dependent transport system permease family
VSVS05_04088	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
VSVS05_04090	COG3385	transposase activity
VSVS05_04094	COG2723	6-phospho-beta-galactosidase activity
VSVS05_04095	COG1263	PTS System
VSVS05_04095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VSVS05_04098	COG3469	chitinase activity
VSVS05_04099	COG3469	chitinase activity
VSVS05_04102	COG2909	trisaccharide binding
VSVS05_04103	COG0058	SHG alpha-glucan phosphorylase activity
VSVS05_04104	COG1640	4-alpha-glucanotransferase
VSVS05_04105	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
VSVS05_04106	COG3788	relative of glutathione S-transferase, MAPEG superfamily
VSVS05_04110	COG0596	Alpha beta hydrolase
VSVS05_04111	COG0471	metal ion transport
VSVS05_04113	COG0010	Belongs to the arginase family
VSVS05_04114	COG1166	arginine decarboxylase activity
VSVS05_04121	COG0513	Belongs to the DEAD box helicase family
VSVS05_04123	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
VSVS05_04124	COG3366	ferrous iron transmembrane transporter activity
VSVS05_04125	COG0700	Nucleoside recognition
VSVS05_04126	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VSVS05_04127	COG3339	Conserved Protein
VSVS05_04128	COG1301	dicarboxylic acid transport
VSVS05_04130	COG2226	methyltransferase
VSVS05_04140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VSVS05_04146	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
VSVS05_04147	COG1162	GTPase activity
VSVS05_04149	COG1999	signal sequence binding
VSVS05_04157	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VSVS05_04160	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VSVS05_04165	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VSVS05_04169	COG1132	(ABC) transporter
VSVS05_04172	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VSVS05_04177	COG1566	PFAM secretion protein HlyD family protein
VSVS05_04179	COG3706	GGDEF domain
VSVS05_04182	COG0813	purine-nucleoside phosphorylase activity
VSVS05_04183	COG3272	Protein of unknown function (DUF1722)
VSVS05_04185	COG0415	Belongs to the DNA photolyase family
VSVS05_04186	COG1388	LysM domain
VSVS05_04186	COG1376	ErfK ybiS ycfS ynhG family protein
VSVS05_04187	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
VSVS05_04188	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VSVS05_04203	COG0842	Transport permease protein
VSVS05_04204	COG1131	(ABC) transporter
VSVS05_04206	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VSVS05_04207	COG2084	Dehydrogenase
VSVS05_04209	COG0513	Belongs to the DEAD box helicase family
VSVS05_04216	COG0739	heme binding
VSVS05_04218	COG1881	PFAM PEBP family protein
VSVS05_04219	COG0772	Belongs to the SEDS family
VSVS05_04220	COG1278	Cold shock
VSVS05_04221	COG0583	DNA-binding transcription factor activity
VSVS05_04222	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VSVS05_04224	COG2249	NAD(P)H dehydrogenase (quinone) activity
VSVS05_04225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VSVS05_04227	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VSVS05_04228	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VSVS05_04235	COG0745	RESPONSE REGULATOR receiver
VSVS05_04235	COG3706	GGDEF domain
VSVS05_04236	COG0745	RESPONSE REGULATOR receiver
VSVS05_04237	COG2205	protein histidine kinase activity
VSVS05_04238	COG4452	Inner membrane protein CreD
VSVS05_04252	COG2233	PERMEase
VSVS05_04254	COG0583	DNA-binding transcription factor activity
VSVS05_04257	COG2721	sulfolactate sulfo-lyase activity
VSVS05_04259	COG4948	Mandelate Racemase Muconate Lactonizing
VSVS05_04260	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
VSVS05_04262	COG1253	flavin adenine dinucleotide binding
VSVS05_04265	COG0583	DNA-binding transcription factor activity
VSVS05_04267	COG0668	transmembrane transport
VSVS05_04284	COG1869	D-ribose catabolic process
VSVS05_04285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VSVS05_04286	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VSVS05_04287	COG0738	Major facilitator superfamily
VSVS05_04289	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VSVS05_04291	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VSVS05_04292	COG1609	Transcriptional regulator
VSVS05_04297	COG0513	Belongs to the DEAD box helicase family
VSVS05_04300	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
VSVS05_04315	COG2003	Belongs to the UPF0758 family
VSVS05_04319	COG1104	cysteine desulfurase activity
VSVS05_04350	COG2916	Histone family protein nucleoid-structuring protein H-NS
VSVS05_04360	COG0776	regulation of translation
VSVS05_04370	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VSVS05_04386	COG2337	Toxic component of a toxin-antitoxin (TA) module
VSVS05_04389	COG3318	Belongs to the UPF0149 family
VSVS05_04389	COG3012	SEC-C Motif Domain Protein
VSVS05_04392	COG3335	DDE superfamily endonuclease
VSVS05_04398	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VSVS05_04413	COG3501	Rhs element vgr protein
VSVS05_04436	COG3081	Nucleoid-associated protein
VSVS05_04437	COG3081	Nucleoid-associated protein
VSVS05_04449	COG1192	Involved in chromosome partitioning
VSVS05_04450	COG1475	DNA binding
VSVS05_04461	COG2003	Belongs to the UPF0758 family