locus-tag	class	description
ITG10_00060	COG2885	chlorophyll binding
ITG10_00070	COG3706	GGDEF domain
ITG10_00075	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ITG10_00080	COG0602	queuosine metabolic process
ITG10_00085	COG0561	phosphatase activity
ITG10_00120	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ITG10_00125	COG0372	Belongs to the citrate synthase family
ITG10_00130	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ITG10_00165	COG4628	conserved protein (DUF2132)
ITG10_00175	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ITG10_00180	COG0363	glucosamine-6-phosphate deaminase activity
ITG10_00185	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ITG10_00190	COG4565	transcriptional regulatory protein
ITG10_00195	COG3290	protein histidine kinase activity
ITG10_00210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ITG10_00225	COG1115	amino acid carrier protein
ITG10_00240	COG1115	amino acid carrier protein
ITG10_00260	COG1280	lysine exporter protein (LysE YggA)
ITG10_00265	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ITG10_00325	COG0730	response to heat
ITG10_00360	COG1247	-acetyltransferase
ITG10_00365	COG4977	sequence-specific DNA binding
ITG10_00390	COG4191	Histidine kinase
ITG10_00390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ITG10_00395	COG0471	metal ion transport
ITG10_00405	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ITG10_00410	COG0494	nUDIX hydrolase
ITG10_00460	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ITG10_00470	COG3033	Beta-eliminating lyase
ITG10_00495	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ITG10_00520	COG2176	DNA-directed DNA polymerase activity
ITG10_00525	COG0517	IMP dehydrogenase activity
ITG10_00530	COG2186	Transcriptional regulator
ITG10_00535	COG1028	Short-chain dehydrogenase reductase Sdr
ITG10_00540	COG2186	Transcriptional regulator
ITG10_00595	COG0840	transmembrane signaling receptor activity
ITG10_00610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ITG10_00620	COG3181	Tripartite tricarboxylate transporter family receptor
ITG10_00635	COG2186	Transcriptional regulator
ITG10_00645	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ITG10_00650	COG3639	organic phosphonate transmembrane transporter activity
ITG10_00675	COG1917	Cupin 2, conserved barrel domain protein
ITG10_00680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ITG10_00685	COG0800	Aldolase
ITG10_00690	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ITG10_00710	COG0010	Belongs to the arginase family
ITG10_00715	COG1166	arginine decarboxylase activity
ITG10_00720	COG2226	methyltransferase
ITG10_00730	COG1309	transcriptional regulator
ITG10_00760	COG3097	Belongs to the UPF0267 family
ITG10_00765	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ITG10_00770	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ITG10_00790	COG4326	sporulation control protein
ITG10_00800	COG1228	amidohydrolase
ITG10_00805	COG0010	Belongs to the arginase family
ITG10_00810	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ITG10_00815	COG2986	histidine ammonia-lyase
ITG10_00830	COG0247	lactate metabolic process
ITG10_00830	COG0277	FAD linked oxidase domain protein
ITG10_00865	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ITG10_00880	COG0281	malic enzyme
ITG10_00885	COG2949	membrane
ITG10_00890	COG0471	metal ion transport
ITG10_00910	COG2203	Gaf domain
ITG10_00910	COG2199	diguanylate cyclase activity
ITG10_00925	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ITG10_00955	COG0492	ferredoxin-NADP+ reductase activity
ITG10_00960	COG4988	ABC transporter
ITG10_00965	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ITG10_00985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ITG10_00990	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ITG10_01015	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ITG10_01040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ITG10_01045	COG3108	Peptidase M15
ITG10_01050	COG2989	Protein conserved in bacteria
ITG10_01075	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ITG10_01085	COG4235	cytochrome complex assembly
ITG10_01085	COG3088	subunit of a heme lyase
ITG10_01095	COG1138	Cytochrome C-type biogenesis protein
ITG10_01100	COG3301	Polysulphide reductase, NrfD
ITG10_01105	COG0437	4 iron, 4 sulfur cluster binding
ITG10_01115	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ITG10_01135	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ITG10_01140	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ITG10_01145	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ITG10_01165	COG0243	molybdopterin cofactor binding
ITG10_01170	COG0437	4 iron, 4 sulfur cluster binding
ITG10_01175	COG3302	dmso reductase anchor subunit
ITG10_01180	COG1058	Belongs to the CinA family
ITG10_01180	COG1546	Belongs to the CinA family
ITG10_01195	COG0019	diaminopimelate decarboxylase activity
ITG10_01235	COG0322	excinuclease ABC activity
ITG10_01240	COG2197	response regulator
ITG10_01245	COG0417	DNA replication proofreading
ITG10_01260	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ITG10_01280	COG1187	pseudouridine synthase activity
ITG10_01285	COG0009	L-threonylcarbamoyladenylate synthase
ITG10_01290	COG0613	PHP domain protein
ITG10_01300	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ITG10_01305	COG0512	Glutamine amidotransferase of anthranilate synthase
ITG10_01310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ITG10_01315	COG0134	indole-3-glycerol-phosphate synthase activity
ITG10_01315	COG0135	phosphoribosylanthranilate isomerase activity
ITG10_01320	COG0133	tryptophan synthase activity
ITG10_01325	COG0159	tryptophan synthase activity
ITG10_01330	COG0330	HflC and HflK could
ITG10_01340	COG1301	dicarboxylic acid transport
ITG10_01350	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ITG10_01360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ITG10_01380	COG2917	probably involved in intracellular septation
ITG10_01385	COG1607	acyl-coa hydrolase
ITG10_01390	COG2350	Protein conserved in bacteria
ITG10_01400	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ITG10_01420	COG1032	radical SAM domain protein
ITG10_01425	COG1396	sequence-specific DNA binding
ITG10_01430	COG3135	benzoate transporter
ITG10_01440	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ITG10_01445	COG0463	Glycosyl transferase, family 2
ITG10_01450	COG0745	RESPONSE REGULATOR receiver
ITG10_01470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ITG10_01475	COG0583	DNA-binding transcription factor activity
ITG10_01490	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ITG10_01515	COG0786	glutamate:sodium symporter activity
ITG10_01530	COG5002	protein histidine kinase activity
ITG10_01530	COG0784	Response regulator, receiver
ITG10_01545	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ITG10_01550	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ITG10_01555	COG2885	chlorophyll binding
ITG10_01560	COG0823	Involved in the tonB-independent uptake of proteins
ITG10_01575	COG0811	peptide transport
ITG10_01580	COG0824	Thioesterase
ITG10_01590	COG4890	Cyd operon protein YbgT
ITG10_01595	COG1294	oxidase, subunit
ITG10_01600	COG1271	oxidase subunit
ITG10_01605	COG2255	four-way junction helicase activity
ITG10_01610	COG0632	four-way junction helicase activity
ITG10_01615	COG0840	transmembrane signaling receptor activity
ITG10_01620	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ITG10_01625	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ITG10_01630	COG1801	Protein of unknown function DUF72
ITG10_01635	COG4106	trans-aconitate 2-methyltransferase activity
ITG10_01640	COG0500	methyltransferase
ITG10_01645	COG0189	ligase activity
ITG10_01645	COG4067	protein conserved in archaea
ITG10_01660	COG3383	formate dehydrogenase (NAD+) activity
ITG10_01665	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ITG10_01670	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
ITG10_01675	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
ITG10_01680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ITG10_01685	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ITG10_01690	COG0745	RESPONSE REGULATOR receiver
ITG10_01695	COG3381	protein complex oligomerization
ITG10_01700	COG1609	Transcriptional regulator
ITG10_01705	COG3070	regulator of competence-specific genes
ITG10_01725	COG0297	glycogen (starch) synthase activity
ITG10_01730	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ITG10_01735	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ITG10_01745	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ITG10_01755	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ITG10_01760	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ITG10_01765	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ITG10_01770	COG0542	response to heat
ITG10_01775	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ITG10_01780	COG1278	Cold shock
ITG10_01800	COG1199	ATP-dependent helicase activity
ITG10_01820	COG2850	peptidyl-arginine hydroxylation
ITG10_01830	COG2814	Major facilitator Superfamily
ITG10_01835	COG1770	oligopeptidase
ITG10_01840	COG0708	Exodeoxyribonuclease III
ITG10_01850	COG4160	amino acid transport
ITG10_01875	COG1882	Formate acetyltransferase
ITG10_01885	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ITG10_01890	COG3013	Belongs to the UPF0304 family
ITG10_01900	COG2766	serine protein kinase
ITG10_01905	COG2718	Belongs to the UPF0229 family
ITG10_01910	COG2719	SpoVR family
ITG10_01920	COG0616	signal peptide processing
ITG10_01925	COG1028	Short-chain dehydrogenase reductase Sdr
ITG10_01930	COG2801	Transposase and inactivated derivatives
ITG10_01935	COG2801	Transposase and inactivated derivatives
ITG10_01940	COG2963	transposase activity
ITG10_01965	COG0835	chemotaxis
ITG10_01965	COG0784	Response regulator, receiver
ITG10_01970	COG1940	carbohydrate kinase activity
ITG10_01975	COG0469	pyruvate kinase activity
ITG10_01980	COG4667	esterase of the alpha-beta hydrolase superfamily
ITG10_01995	COG2801	Transposase and inactivated derivatives
ITG10_02000	COG2801	Transposase and inactivated derivatives
ITG10_02015	COG0084	hydrolase, TatD family'
ITG10_02020	COG0470	DNA polymerase III
ITG10_02025	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ITG10_02030	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ITG10_02035	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ITG10_02060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ITG10_02065	COG0416	fatty acid biosynthetic process
ITG10_02070	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ITG10_02075	COG1399	metal-binding, possibly nucleic acid-binding protein
ITG10_02085	COG0564	pseudouridine synthase activity
ITG10_02090	COG1530	ribonuclease E activity
ITG10_02095	COG0659	secondary active sulfate transmembrane transporter activity
ITG10_02100	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ITG10_02105	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ITG10_02110	COG2982	Protein involved in outer membrane biogenesis
ITG10_02115	COG0572	uridine kinase
ITG10_02120	COG0489	protein tyrosine kinase activity
ITG10_02125	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ITG10_02125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ITG10_02135	COG2186	Transcriptional regulator
ITG10_02140	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ITG10_02145	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ITG10_02150	COG0653	protein targeting
ITG10_02155	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ITG10_02160	COG3706	GGDEF domain
ITG10_02165	COG0366	Alpha amylase catalytic
ITG10_02175	COG3092	negative regulation of chromosome organization
ITG10_02180	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ITG10_02185	COG0857	belongs to the CobB CobQ family
ITG10_02185	COG0280	phosphate acetyltransferase
ITG10_02195	COG0435	Glutathione S-transferase
ITG10_02205	COG0444	Belongs to the ABC transporter superfamily
ITG10_02210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ITG10_02215	COG0601	transmembrane transport
ITG10_02225	COG0314	molybdopterin synthase activity
ITG10_02230	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ITG10_02235	COG0315	cyclic pyranopterin monophosphate synthase activity
ITG10_02240	COG0521	Mo-molybdopterin cofactor biosynthetic process
ITG10_02245	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ITG10_02250	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ITG10_02260	COG2198	Histidine kinase
ITG10_02265	COG2204	response regulator
ITG10_02270	COG0556	nucleotide-excision repair
ITG10_02280	COG4657	Part of a membrane complex involved in electron transport
ITG10_02285	COG2878	Part of a membrane complex involved in electron transport
ITG10_02290	COG4656	Part of a membrane complex involved in electron transport
ITG10_02295	COG4658	electron transport chain
ITG10_02300	COG4659	FMN binding
ITG10_02305	COG4660	Part of a membrane complex involved in electron transport
ITG10_02310	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ITG10_02315	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ITG10_02320	COG0346	lactoylglutathione lyase activity
ITG10_02340	COG2056	Na+-H+ antiporter family
ITG10_02360	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ITG10_02390	COG1012	belongs to the aldehyde dehydrogenase family
ITG10_02390	COG1454	alcohol dehydrogenase
ITG10_02395	COG2095	MarC family integral membrane protein
ITG10_02400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ITG10_02410	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ITG10_02415	COG1757	Na H antiporter
ITG10_02430	COG3081	Nucleoid-associated protein
ITG10_02435	COG3082	Protein of unknown function (DUF1414)
ITG10_02465	COG0582	viral genome integration into host DNA
ITG10_02485	COG4372	Transposase
ITG10_02515	COG2274	protein secretion by the type I secretion system
ITG10_02550	COG2801	Transposase and inactivated derivatives
ITG10_02600	COG0840	transmembrane signaling receptor activity
ITG10_02605	COG0123	including yeast histone deacetylase and acetoin utilization protein
ITG10_02620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ITG10_02625	COG0778	Nitroreductase
ITG10_02630	COG1902	pentaerythritol trinitrate reductase activity
ITG10_02630	COG0446	pyridine nucleotide-disulphide oxidoreductase
ITG10_02635	COG0616	signal peptide processing
ITG10_02640	COG0252	asparaginase activity
ITG10_02645	COG3139	Protein of unknown function (DUF1315)
ITG10_02655	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ITG10_02660	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ITG10_02675	COG2226	methyltransferase
ITG10_02695	COG2983	Belongs to the UPF0260 family
ITG10_02710	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ITG10_02715	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ITG10_02720	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ITG10_02725	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ITG10_02730	COG2832	Protein of unknown function (DUF454)
ITG10_02740	COG0745	RESPONSE REGULATOR receiver
ITG10_02745	COG0583	DNA-binding transcription factor activity
ITG10_02750	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ITG10_02755	COG1286	toxin biosynthetic process
ITG10_02760	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ITG10_02765	COG0285	dihydrofolate synthase activity
ITG10_02770	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ITG10_02775	COG0101	tRNA pseudouridine synthase activity
ITG10_02785	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ITG10_02790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ITG10_02795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ITG10_02805	COG0431	NADPH-dependent FMN reductase
ITG10_02815	COG3101	peptidyl-lysine hydroxylation
ITG10_02825	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ITG10_02830	COG2153	protein acetylation
ITG10_02865	COG2391	methyltransferase activity
ITG10_02940	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ITG10_02950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ITG10_02955	COG0583	DNA-binding transcription factor activity
ITG10_02960	COG2951	lytic endotransglycosylase activity
ITG10_02965	COG3100	YcgL domain-containing protein
ITG10_02970	COG0850	regulation of cytokinetic process
ITG10_02975	COG2894	cell division
ITG10_02980	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ITG10_02985	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ITG10_02990	COG0318	PFAM AMP-dependent synthetase and ligase
ITG10_02995	COG0596	Alpha beta hydrolase
ITG10_03010	COG1214	PFAM Peptidase M22, glycoprotease
ITG10_03015	COG1199	ATP-dependent helicase activity
ITG10_03035	COG0788	formyltetrahydrofolate deformylase activity
ITG10_03040	COG3102	Protein conserved in bacteria
ITG10_03045	COG0018	arginyl-trna synthetase
ITG10_03070	COG1918	ferrous iron import across plasma membrane
ITG10_03080	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ITG10_03085	COG1121	(ABC) transporter
ITG10_03090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ITG10_03100	COG0045	succinate-CoA ligase (ADP-forming) activity
ITG10_03105	COG0508	dehydrogenase complex catalyzes the overall conversion of
ITG10_03110	COG0567	Dehydrogenase, E1 component
ITG10_03115	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ITG10_03120	COG1053	succinate dehydrogenase
ITG10_03125	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ITG10_03140	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ITG10_03155	COG0033	Phosphoglucomutase
ITG10_03160	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ITG10_03165	COG0596	Alpha beta hydrolase
ITG10_03190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ITG10_03195	COG2190	(PTS) system
ITG10_03195	COG1263	PTS System
ITG10_03195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ITG10_03200	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ITG10_03205	COG1846	Transcriptional regulator
ITG10_03205	COG1940	carbohydrate kinase activity
ITG10_03210	COG4651	solute:proton antiporter activity
ITG10_03210	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ITG10_03215	COG0367	asparagine synthase
ITG10_03220	COG0250	Participates in transcription elongation, termination and antitermination
ITG10_03225	COG3104	oligopeptide transport
ITG10_03230	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ITG10_03235	COG0563	adenylate kinase activity
ITG10_03240	COG0326	Molecular chaperone. Has ATPase activity
ITG10_03245	COG3710	Transcriptional regulator
ITG10_03265	COG0622	Phosphoesterase
ITG10_03290	COG1090	epimerase
ITG10_03295	COG0300	oxidoreductase activity
ITG10_03300	COG3118	belongs to the thioredoxin family
ITG10_03305	COG0330	HflC and HflK could
ITG10_03315	COG0789	Transcriptional regulator
ITG10_03335	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ITG10_03340	COG3115	cell septum assembly
ITG10_03345	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
ITG10_03355	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ITG10_03365	COG2190	(PTS) system
ITG10_03370	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ITG10_03375	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ITG10_03380	COG2837	iron assimilation
ITG10_03405	COG1393	Belongs to the ArsC family
ITG10_03410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ITG10_03425	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ITG10_03430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ITG10_03435	COG2716	regulation of RNA biosynthetic process
ITG10_03465	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ITG10_03495	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ITG10_03510	COG4783	chaperone-mediated protein folding
ITG10_03515	COG1393	Belongs to the ArsC family
ITG10_03530	COG2801	Transposase and inactivated derivatives
ITG10_03535	COG2801	Transposase and inactivated derivatives
ITG10_03540	COG2801	Transposase and inactivated derivatives
ITG10_03545	COG2963	transposase activity
ITG10_03565	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ITG10_03570	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ITG10_03575	COG0121	glutamine amidotransferase
ITG10_03580	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ITG10_03585	COG1960	acyl-CoA dehydrogenase activity
ITG10_03595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ITG10_03600	COG0328	RNA-DNA hybrid ribonuclease activity
ITG10_03605	COG2226	methyltransferase
ITG10_03610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ITG10_03615	COG0741	lytic transglycosylase activity
ITG10_03615	COG1388	LysM domain
ITG10_03625	COG3021	interspecies interaction between organisms
ITG10_03635	COG0347	Belongs to the P(II) protein family
ITG10_03645	COG0037	tRNA processing
ITG10_03650	COG0825	malonyl-CoA metabolic process
ITG10_03655	COG0587	DNA-directed DNA polymerase activity
ITG10_03660	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ITG10_03670	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ITG10_03675	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ITG10_03680	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ITG10_03685	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ITG10_03695	COG0750	zinc metalloprotease
ITG10_03705	COG0575	Belongs to the CDS family
ITG10_03710	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ITG10_03715	COG0233	cytoplasmic translational termination
ITG10_03720	COG0528	UMP kinase activity
ITG10_03730	COG0052	Belongs to the universal ribosomal protein uS2 family
ITG10_03735	COG0024	Methionine aminopeptidase
ITG10_03740	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ITG10_03750	COG0564	pseudouridine synthase activity
ITG10_03755	COG3098	single-species biofilm formation
ITG10_03780	COG1671	Belongs to the UPF0178 family
ITG10_03790	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ITG10_03800	COG0254	rRNA binding
ITG10_03805	COG1720	tRNA m6t6A37 methyltransferase activity
ITG10_03810	COG0442	prolyl-tRNA aminoacylation
ITG10_03840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ITG10_03855	COG0366	Alpha amylase catalytic
ITG10_03860	COG1263	PTS System
ITG10_03860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ITG10_03865	COG1609	Transcriptional regulator
ITG10_03875	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ITG10_03885	COG2011	ABC-type metal ion transport system permease component
ITG10_03890	COG1464	Belongs to the NlpA lipoprotein family
ITG10_03900	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
ITG10_03910	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ITG10_03910	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ITG10_03925	COG1611	Belongs to the LOG family
ITG10_03930	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ITG10_03935	COG2963	transposase activity
ITG10_03940	COG2801	Transposase and inactivated derivatives
ITG10_03945	COG2801	Transposase and inactivated derivatives
ITG10_03960	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
ITG10_03975	COG0583	DNA-binding transcription factor activity
ITG10_03985	COG0301	tRNA thio-modification
ITG10_03985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ITG10_03995	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ITG10_04000	COG1722	exodeoxyribonuclease VII activity
ITG10_04005	COG0142	geranyltranstransferase activity
ITG10_04010	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ITG10_04020	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ITG10_04025	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ITG10_04030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ITG10_04050	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ITG10_04050	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ITG10_04055	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ITG10_04060	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ITG10_04075	COG1073	alpha beta
ITG10_04080	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ITG10_04085	COG2252	PERMEase
ITG10_04090	COG2195	Cleaves the N-terminal amino acid of tripeptides
ITG10_04120	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ITG10_04135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ITG10_04145	COG1263	PTS System
ITG10_04145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ITG10_04150	COG1609	Transcriptional regulator
ITG10_04160	COG2017	converts alpha-aldose to the beta-anomer
ITG10_04170	COG1085	galactose-1-phosphate uridylyltransferase
ITG10_04175	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ITG10_04180	COG1609	Transcriptional regulator
ITG10_04190	COG2731	YhcH YjgK YiaL family protein
ITG10_04200	COG0531	amino acid
ITG10_04215	COG3250	beta-galactosidase activity
ITG10_04225	COG0395	ABC-type sugar transport system, permease component
ITG10_04230	COG1175	transmembrane transport
ITG10_04240	COG0534	Mate efflux family protein
ITG10_04250	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ITG10_04260	COG1609	Transcriptional regulator
ITG10_04270	COG0583	DNA-binding transcription factor activity
ITG10_04275	COG2059	Chromate
ITG10_04310	COG4964	Belongs to the GSP D family
ITG10_04345	COG1022	Amp-dependent synthetase and ligase
ITG10_04385	COG0583	DNA-binding transcription factor activity
ITG10_04395	COG0583	DNA-binding transcription factor activity
ITG10_04400	COG4628	conserved protein (DUF2132)
ITG10_04405	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ITG10_04410	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ITG10_04420	COG0560	Phosphoserine phosphatase
ITG10_04430	COG0813	purine-nucleoside phosphorylase activity
ITG10_04435	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ITG10_04440	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ITG10_04445	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ITG10_04450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ITG10_04455	COG0084	hydrolase, TatD family'
ITG10_04465	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ITG10_04480	COG3153	acetyltransferase
ITG10_04485	COG3154	lipid carrier protein
ITG10_04495	COG0826	peptidase U32
ITG10_04500	COG0826	peptidase U32
ITG10_04505	COG0534	Mate efflux family protein
ITG10_04515	COG2963	transposase activity
ITG10_04520	COG2801	Transposase and inactivated derivatives
ITG10_04525	COG2801	Transposase and inactivated derivatives
ITG10_04535	COG1185	polyribonucleotide nucleotidyltransferase activity
ITG10_04540	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ITG10_04545	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ITG10_04550	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ITG10_04555	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ITG10_04560	COG0195	Participates in both transcription termination and antitermination
ITG10_04565	COG0779	Required for maturation of 30S ribosomal subunits
ITG10_04580	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ITG10_04585	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ITG10_04590	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ITG10_04595	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ITG10_04600	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ITG10_04605	COG1534	Rna-binding protein
ITG10_04610	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ITG10_04620	COG2027	D-alanyl-D-alanine carboxypeptidase
ITG10_04630	COG2239	Acts as a magnesium transporter
ITG10_04635	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ITG10_04640	COG0739	heme binding
ITG10_04655	COG0316	Belongs to the HesB IscA family
ITG10_04660	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ITG10_04665	COG0628	permease
ITG10_04670	COG2813	Specifically methylates the guanine in position
ITG10_04680	COG0747	negative chemotaxis
ITG10_04690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ITG10_04695	COG0444	Belongs to the ABC transporter superfamily
ITG10_04700	COG4608	Belongs to the ABC transporter superfamily
ITG10_04710	COG2971	BadF BadG BcrA BcrD
ITG10_04725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ITG10_04730	COG3842	ATPase activity
ITG10_04740	COG1840	ABC-type Fe3 transport system, periplasmic component
ITG10_04745	COG0004	ammonium transporteR
ITG10_04760	COG1049	propionate catabolic process, 2-methylcitrate cycle
ITG10_04765	COG1752	Esterase of the alpha-beta hydrolase superfamily
ITG10_04770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ITG10_04775	COG1643	Atp-dependent helicase
ITG10_04780	COG1489	DNA binding
ITG10_04800	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ITG10_04805	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ITG10_04810	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ITG10_04815	COG0842	Transport permease protein
ITG10_04820	COG1131	(ABC) transporter
ITG10_04825	COG0659	secondary active sulfate transmembrane transporter activity
ITG10_04830	COG0288	reversible hydration of carbon dioxide
ITG10_04850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ITG10_04855	COG0508	dehydrogenase complex catalyzes the overall conversion of
ITG10_04860	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ITG10_04865	COG2186	Transcriptional regulator
ITG10_04875	COG0157	Belongs to the NadC ModD family
ITG10_04885	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ITG10_04890	COG1459	type II secretion system
ITG10_04900	COG0237	dephospho-CoA kinase activity
ITG10_04905	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ITG10_04930	COG0335	large ribosomal subunit rRNA binding
ITG10_04935	COG0336	Belongs to the RNA methyltransferase TrmD family
ITG10_04940	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ITG10_04950	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ITG10_04955	COG4137	Cytochrome C assembly protein
ITG10_04960	COG4536	flavin adenine dinucleotide binding
ITG10_04965	COG1854	S-ribosylhomocysteine lyase activity
ITG10_04975	COG2918	glutathione biosynthetic process
ITG10_04980	COG0612	Peptidase, M16
ITG10_04985	COG1238	metal cluster binding
ITG10_04995	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ITG10_05000	COG0511	ligase activity, forming carbon-carbon bonds
ITG10_05000	COG5016	pyruvate
ITG10_05005	COG3630	sodium ion export across plasma membrane
ITG10_05065	COG0527	aspartate kinase activity
ITG10_05075	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ITG10_05080	COG1546	Belongs to the CinA family
ITG10_05085	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ITG10_05090	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ITG10_05100	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ITG10_05105	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ITG10_05110	COG0585	pseudouridine synthase activity
ITG10_05120	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ITG10_05125	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ITG10_05130	COG0148	phosphopyruvate hydratase activity
ITG10_05135	COG0504	CTP synthase activity
ITG10_05140	COG3956	TIGRFAM MazG family protein
ITG10_05145	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ITG10_05150	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ITG10_05155	COG3850	Histidine kinase
ITG10_05155	COG2205	protein histidine kinase activity
ITG10_05155	COG4999	Histidine kinase
ITG10_05155	COG3437	response regulator, receiver
ITG10_05160	COG0736	holo-[acyl-carrier-protein] synthase activity
ITG10_05165	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ITG10_05170	COG1381	Involved in DNA repair and RecF pathway recombination
ITG10_05175	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ITG10_05180	COG0571	ribonuclease III activity
ITG10_05190	COG0481	GTPase activity
ITG10_05210	COG1595	DNA-templated transcription, initiation
ITG10_05215	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ITG10_05220	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ITG10_05225	COG0354	folic acid binding
ITG10_05240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ITG10_05245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ITG10_05250	COG3079	Belongs to the UPF0149 family
ITG10_05255	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ITG10_05265	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ITG10_05270	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ITG10_05275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ITG10_05300	COG0668	transmembrane transport
ITG10_05305	COG0191	fructose-bisphosphate aldolase activity
ITG10_05320	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ITG10_05325	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ITG10_05335	COG3091	SprT-like family
ITG10_05340	COG2356	endonuclease I
ITG10_05345	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ITG10_05350	COG0189	ligase activity
ITG10_05355	COG1678	Uncharacterized ACR, COG1678
ITG10_05360	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ITG10_05380	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ITG10_05385	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ITG10_05390	COG0762	integral membrane protein
ITG10_05405	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ITG10_05410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ITG10_05415	COG2066	Belongs to the glutaminase family
ITG10_05430	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ITG10_05435	COG0741	lytic transglycosylase activity
ITG10_05475	COG0840	transmembrane signaling receptor activity
ITG10_05595	COG0795	lipopolysaccharide-transporting ATPase activity
ITG10_05600	COG0795	lipopolysaccharide-transporting ATPase activity
ITG10_05605	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ITG10_05610	COG2927	DNA polymerase III (CHI subunit)
ITG10_05615	COG0525	valine-tRNA ligase activity
ITG10_05625	COG0456	acetyltransferase
ITG10_05655	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
ITG10_05660	COG0251	oxidation-reduction process
ITG10_05665	COG0204	Acyl-transferase
ITG10_05670	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ITG10_05675	COG5007	Belongs to the BolA IbaG family
ITG10_05685	COG2854	intermembrane phospholipid transfer
ITG10_05690	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ITG10_05695	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ITG10_05700	COG1127	ABC transporter
ITG10_05710	COG0517	IMP dehydrogenase activity
ITG10_05710	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ITG10_05715	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ITG10_05725	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ITG10_05730	COG1137	ATPase activity
ITG10_05740	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ITG10_05745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ITG10_05750	COG1660	Displays ATPase and GTPase activities
ITG10_05755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ITG10_05760	COG2239	Acts as a magnesium transporter
ITG10_05770	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ITG10_05775	COG0729	surface antigen
ITG10_05780	COG2911	Protein conserved in bacteria
ITG10_05785	COG2105	PFAM AIG2 family protein
ITG10_05800	COG0312	modulator of DNA gyrase
ITG10_05805	COG3028	Belongs to the UPF0307 family
ITG10_05810	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ITG10_05815	COG1178	ABC-type Fe3 transport system permease component
ITG10_05825	COG0163	prenyltransferase activity
ITG10_05830	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ITG10_05835	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ITG10_05850	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ITG10_05885	COG0529	Catalyzes the synthesis of activated sulfate
ITG10_05890	COG3273	potassium ion transport
ITG10_05890	COG0471	metal ion transport
ITG10_05895	COG2895	sulfate adenylyltransferase (ATP) activity
ITG10_05900	COG0175	sulfate reduction
ITG10_05905	COG0737	Belongs to the 5'-nucleotidase family
ITG10_05955	COG2153	protein acetylation
ITG10_05965	COG3061	Opacity-associated protein A
ITG10_05965	COG3266	domain, Protein
ITG10_05970	COG0545	Peptidyl-prolyl cis-trans isomerase
ITG10_05985	COG0203	ribosomal protein L17
ITG10_05990	COG0202	RNA polymerase activity
ITG10_05995	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ITG10_06000	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ITG10_06005	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ITG10_06010	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ITG10_06015	COG0201	protein transport
ITG10_06020	COG0200	Binds to the 23S rRNA
ITG10_06025	COG1841	ribosomal large subunit assembly
ITG10_06030	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ITG10_06035	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ITG10_06040	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ITG10_06045	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ITG10_06050	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ITG10_06055	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ITG10_06060	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ITG10_06065	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ITG10_06070	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ITG10_06080	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ITG10_06085	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ITG10_06095	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ITG10_06100	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ITG10_06105	COG0089	rRNA binding
ITG10_06110	COG0088	Forms part of the polypeptide exit tunnel
ITG10_06115	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ITG10_06130	COG2906	2 iron, 2 sulfur cluster binding
ITG10_06135	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ITG10_06140	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ITG10_06160	COG2923	Belongs to the DsrF TusC family
ITG10_06165	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ITG10_06170	COG2964	Protein conserved in bacteria
ITG10_06175	COG0545	Peptidyl-prolyl cis-trans isomerase
ITG10_06185	COG2900	Belongs to the SlyX family
ITG10_06195	COG1047	Peptidyl-prolyl cis-trans
ITG10_06210	COG2249	NAD(P)H dehydrogenase (quinone) activity
ITG10_06215	COG0488	(ABC) transporter
ITG10_06225	COG0429	hydrolase of the alpha beta-hydrolase fold
ITG10_06230	COG3089	Belongs to the UPF0270 family
ITG10_06235	COG3954	Phosphoribulokinase
ITG10_06240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ITG10_06250	COG1012	belongs to the aldehyde dehydrogenase family
ITG10_06260	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ITG10_06265	COG0512	Glutamine amidotransferase of anthranilate synthase
ITG10_06275	COG0180	Tryptophanyl-tRNA synthetase
ITG10_06280	COG0546	phosphoglycolate phosphatase activity
ITG10_06285	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ITG10_06290	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ITG10_06300	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ITG10_06335	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ITG10_06345	COG0678	peroxiredoxin activity
ITG10_06345	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ITG10_06350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ITG10_06355	COG0251	oxidation-reduction process
ITG10_06365	COG0165	Argininosuccinate lyase
ITG10_06365	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ITG10_06380	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ITG10_06385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ITG10_06390	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ITG10_06400	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ITG10_06405	COG0460	homoserine dehydrogenase
ITG10_06405	COG0527	aspartate kinase activity
ITG10_06410	COG0626	cystathionine gamma-synthase activity
ITG10_06415	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
ITG10_06420	COG0281	malic enzyme
ITG10_06425	COG0254	rRNA binding
ITG10_06430	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ITG10_06435	COG1609	Transcriptional regulator
ITG10_06445	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ITG10_06450	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ITG10_06455	COG1575	Belongs to the MenA family. Type 1 subfamily
ITG10_06460	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ITG10_06465	COG3074	FtsZ-dependent cytokinesis
ITG10_06470	COG1494	fructose-1,6-bisphosphatase
ITG10_06485	COG3152	Membrane
ITG10_06495	COG0149	triose-phosphate isomerase activity
ITG10_06500	COG0205	6-phosphofructokinase activity
ITG10_06505	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ITG10_06515	COG0745	RESPONSE REGULATOR receiver
ITG10_06520	COG2205	protein histidine kinase activity
ITG10_06530	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ITG10_06540	COG1027	Aspartate ammonia-lyase
ITG10_06545	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ITG10_06550	COG1288	antiporter activity
ITG10_06560	COG0549	Belongs to the carbamate kinase family
ITG10_06565	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ITG10_06570	COG0540	Belongs to the ATCase OTCase family
ITG10_06575	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
ITG10_06580	COG1438	arginine binding
ITG10_06585	COG4232	protein-disulfide reductase activity
ITG10_06595	COG3263	regulation of cellular component size
ITG10_06605	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ITG10_06620	COG0784	Response regulator, receiver
ITG10_06620	COG2198	Histidine kinase
ITG10_06620	COG2205	protein histidine kinase activity
ITG10_06625	COG2814	Major facilitator Superfamily
ITG10_06640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ITG10_06650	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ITG10_06655	COG0511	ligase activity, forming carbon-carbon bonds
ITG10_06660	COG0439	Biotin carboxylase
ITG10_06665	COG2264	protein methyltransferase activity
ITG10_06670	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ITG10_06675	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ITG10_06680	COG0789	Transcriptional regulator
ITG10_06685	COG0138	bifunctional purine biosynthesis protein purh
ITG10_06690	COG0151	Belongs to the GarS family
ITG10_06705	COG1253	flavin adenine dinucleotide binding
ITG10_06710	COG3068	Protein conserved in bacteria
ITG10_06720	COG1573	uracil-dna glycosylase
ITG10_06735	COG2816	NAD+ diphosphatase activity
ITG10_06740	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
ITG10_06755	COG0222	ribosome binding
ITG10_06760	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ITG10_06765	COG0081	regulation of translation
ITG10_06775	COG0250	Participates in transcription elongation, termination and antitermination
ITG10_06780	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ITG10_06785	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ITG10_06810	COG1072	(Pantothenic acid kinase))
ITG10_06820	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ITG10_06830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ITG10_06860	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ITG10_06875	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ITG10_06890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ITG10_06895	COG0534	Mate efflux family protein
ITG10_06900	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ITG10_06905	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ITG10_06910	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ITG10_06915	COG2937	Belongs to the GPAT DAPAT family
ITG10_06920	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ITG10_06925	COG3161	chorismate lyase activity
ITG10_06930	COG1580	Controls the rotational direction of flagella during chemotaxis
ITG10_06935	COG0705	Rhomboid family
ITG10_06940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ITG10_06950	COG2177	Part of the ABC transporter FtsEX involved in
ITG10_06955	COG2884	Cell division ATP-binding protein ftsE
ITG10_06960	COG0552	protein localization to endoplasmic reticulum
ITG10_06960	COG0552	protein localization to endoplasmic reticulum
ITG10_06965	COG0742	ribosomal rna small subunit methyltransferase
ITG10_06975	COG2095	MarC family integral membrane protein
ITG10_07015	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ITG10_07020	COG0640	Transcriptional regulator
ITG10_07025	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ITG10_07030	COG1280	lysine exporter protein (LysE YggA)
ITG10_07035	COG2267	carboxylic ester hydrolase activity
ITG10_07040	COG0561	phosphatase activity
ITG10_07055	COG3148	PFAM DTW domain containing protein
ITG10_07065	COG2199	diguanylate cyclase activity
ITG10_07065	COG2200	EAL domain
ITG10_07065	COG3287	FIST C domain
ITG10_07070	COG2199	diguanylate cyclase activity
ITG10_07070	COG2200	EAL domain
ITG10_07070	COG3287	FIST C domain
ITG10_07075	COG1011	Hydrolase
ITG10_07080	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ITG10_07090	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ITG10_07095	COG0019	diaminopimelate decarboxylase activity
ITG10_07105	COG1965	Belongs to the frataxin family
ITG10_07110	COG3072	Adenylate cyclase
ITG10_07115	COG0181	hydroxymethylbilane synthase activity
ITG10_07120	COG1587	Uroporphyrinogen-III synthase
ITG10_07125	COG2959	enzyme of heme biosynthesis
ITG10_07185	COG2871	sodium ion transport
ITG10_07190	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ITG10_07205	COG3118	belongs to the thioredoxin family
ITG10_07210	COG0513	Belongs to the DEAD box helicase family
ITG10_07215	COG0248	Ppx GppA phosphatase
ITG10_07225	COG0861	Integral membrane protein TerC family
ITG10_07235	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ITG10_07245	COG0514	ATP-dependent DNA helicase (RecQ)
ITG10_07250	COG2962	Rard protein
ITG10_07260	COG1280	lysine exporter protein (LysE YggA)
ITG10_07265	COG0405	Gamma-glutamyltransferase
ITG10_07275	COG0210	DNA helicase
ITG10_07285	COG3220	belongs to the UPF0276 family
ITG10_07315	COG0006	proline dipeptidase activity
ITG10_07315	COG0006	proline dipeptidase activity
ITG10_07325	COG2022	thiamine diphosphate biosynthetic process
ITG10_07330	COG2104	thiamine diphosphate biosynthetic process
ITG10_07335	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ITG10_07340	COG0352	thiamine-phosphate diphosphorylase activity
ITG10_07345	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ITG10_07355	COG2132	Multicopper oxidase
ITG10_07400	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ITG10_07410	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ITG10_07415	COG0408	coproporphyrinogen oxidase activity
ITG10_07420	COG0009	L-threonylcarbamoyladenylate synthase
ITG10_07425	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ITG10_07430	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ITG10_07435	COG0551	DNA topoisomerase type I activity
ITG10_07440	COG2922	Belongs to the Smg family
ITG10_07445	COG0758	DNA mediated transformation
ITG10_07455	COG0242	peptide deformylase activity
ITG10_07465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ITG10_07465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ITG10_07470	COG0569	domain protein
ITG10_07475	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ITG10_07485	COG1272	protein, Hemolysin III
ITG10_07490	COG4326	sporulation control protein
ITG10_07500	COG3084	Protein conserved in bacteria
ITG10_07510	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ITG10_07515	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ITG10_07525	COG0606	chelatase, subunit chli
ITG10_07535	COG3978	acetolactate synthase activity
ITG10_07540	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ITG10_07545	COG0129	dihydroxy-acid dehydratase activity
ITG10_07555	COG0583	DNA-binding transcription factor activity
ITG10_07560	COG2814	Major facilitator Superfamily
ITG10_07565	COG3706	GGDEF domain
ITG10_07575	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ITG10_07580	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ITG10_07585	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ITG10_07590	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ITG10_07595	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ITG10_07600	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ITG10_07615	COG3312	ion transport
ITG10_07620	COG1475	DNA binding
ITG10_07625	COG1192	Involved in chromosome partitioning
ITG10_07630	COG0357	Ribosomal RNA small subunit methyltransferase G
ITG10_07635	COG0445	tRNA wobble uridine modification
ITG10_07640	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ITG10_07650	COG0706	membrane insertase activity
ITG10_07655	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ITG10_07660	COG0594	ribonuclease P activity
ITG10_07665	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ITG10_07670	COG1126	abc transporter atp-binding protein
ITG10_07685	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ITG10_07690	COG0592	DNA-directed DNA polymerase activity
ITG10_07695	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ITG10_07700	COG0187	DNA topoisomerase II activity
ITG10_07705	COG0071	Belongs to the small heat shock protein (HSP20) family
ITG10_07710	COG3977	Valine--pyruvate aminotransferase
ITG10_07715	COG0366	Alpha amylase catalytic
ITG10_07720	COG0751	glycine-tRNA ligase activity
ITG10_07725	COG0752	glycyl-tRNA synthetase alpha subunit
ITG10_07730	COG2119	membrane
ITG10_07740	COG0425	Belongs to the sulfur carrier protein TusA family
ITG10_07755	COG0604	alcohol dehydrogenase
ITG10_07760	COG0183	Belongs to the thiolase family
ITG10_07765	COG1024	Enoyl-CoA hydratase
ITG10_07765	COG1250	3-hydroxyacyl-CoA dehydrogenase
ITG10_07770	COG1739	Uncharacterized protein family UPF0029
ITG10_07775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ITG10_07780	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ITG10_07930	COG4964	Belongs to the GSP D family
ITG10_07960	COG0583	DNA-binding transcription factor activity
ITG10_07965	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ITG10_07970	COG2960	long-chain fatty acid transporting porin activity
ITG10_07975	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ITG10_07980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ITG10_07985	COG1309	transcriptional regulator
ITG10_08035	COG0601	transmembrane transport
ITG10_08040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ITG10_08120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ITG10_08125	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ITG10_08135	COG1522	sequence-specific DNA binding
ITG10_08140	COG5002	protein histidine kinase activity
ITG10_08140	COG5001	Diguanylate cyclase
ITG10_08145	COG0742	ribosomal rna small subunit methyltransferase
ITG10_08160	COG0589	response to stress
ITG10_08165	COG1528	Iron-storage protein
ITG10_08175	COG2081	HI0933 family
ITG10_08185	COG1322	Protein conserved in bacteria
ITG10_08190	COG2226	methyltransferase
ITG10_08195	COG3165	ubiquinone biosynthetic process from chorismate
ITG10_08200	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ITG10_08205	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ITG10_08210	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ITG10_08215	COG0805	protein transport
ITG10_08220	COG0084	hydrolase, TatD family'
ITG10_08235	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ITG10_08235	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ITG10_08260	COG3078	GTPase activator activity
ITG10_08285	COG3852	Histidine kinase
ITG10_08295	COG0174	glutamine synthetase
ITG10_08300	COG1217	gtp-binding protein TYPA
ITG10_08325	COG1295	ribonuclease BN
ITG10_08330	COG1490	D-aminoacyl-tRNA deacylase activity
ITG10_08335	COG0456	acetyltransferase
ITG10_08350	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ITG10_08360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ITG10_08365	COG3031	protein transport across the cell outer membrane
ITG10_08375	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ITG10_08380	COG1459	type II secretion system
ITG10_08385	COG2165	general secretion pathway protein
ITG10_08390	COG2165	general secretion pathway protein
ITG10_08395	COG2165	general secretion pathway protein
ITG10_08400	COG4795	General secretion pathway protein
ITG10_08405	COG3156	type II secretion system protein K
ITG10_08410	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ITG10_08415	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ITG10_08425	COG1218	3'(2'),5'-bisphosphate nucleotidase
ITG10_08430	COG0494	nUDIX hydrolase
ITG10_08435	COG0316	Belongs to the HesB IscA family
ITG10_08435	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ITG10_08445	COG0596	Alpha beta hydrolase
ITG10_08455	COG2183	response to ionizing radiation
ITG10_08460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ITG10_08475	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ITG10_08480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ITG10_08485	COG1758	RNA polymerase activity
ITG10_08490	COG0194	GDP metabolic process
ITG10_08495	COG2252	PERMEase
ITG10_08505	COG1278	Cold shock
ITG10_08510	COG1561	YicC-like family, N-terminal region
ITG10_08515	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ITG10_08520	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ITG10_08525	COG1560	Kdo2-lipid A biosynthetic process
ITG10_08530	COG1309	transcriptional regulator
ITG10_08540	COG2003	Belongs to the UPF0758 family
ITG10_08545	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ITG10_08550	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ITG10_08560	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ITG10_08585	COG0859	PFAM glycosyl transferase family 9
ITG10_08590	COG3642	lipopolysaccharide core region biosynthetic process
ITG10_08595	COG1519	Transferase
ITG10_08605	COG0463	Glycosyl transferase, family 2
ITG10_08615	COG1086	Polysaccharide biosynthesis protein
ITG10_08620	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ITG10_08635	COG0107	imidazoleglycerol-phosphate synthase activity
ITG10_08640	COG1083	cytidylyl-transferase
ITG10_08650	COG2089	acid synthase
ITG10_08665	COG1560	Kdo2-lipid A biosynthetic process
ITG10_08685	COG4942	peptidase
ITG10_08690	COG1045	serine acetyltransferase
ITG10_08700	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ITG10_08705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ITG10_08720	COG1091	dTDP-4-dehydrorhamnose reductase activity
ITG10_08760	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ITG10_08785	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ITG10_08805	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ITG10_08810	COG1596	polysaccharide export
ITG10_08835	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ITG10_08840	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ITG10_08880	COG1045	serine acetyltransferase
ITG10_08915	COG0471	metal ion transport
ITG10_08915	COG3273	potassium ion transport
ITG10_08920	COG0175	sulfate reduction
ITG10_08925	COG0529	Catalyzes the synthesis of activated sulfate
ITG10_08935	COG2895	sulfate adenylyltransferase (ATP) activity
ITG10_08940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ITG10_08945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ITG10_09185	COG2433	Pfam Transposase IS66
ITG10_09215	COG3311	Transcriptional regulator
ITG10_09225	COG2161	toxin-antitoxin pair type II binding
ITG10_09270	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ITG10_09285	COG2161	toxin-antitoxin pair type II binding
ITG10_09290	COG4115	mRNA cleavage
ITG10_09300	COG0534	Mate efflux family protein
ITG10_09305	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ITG10_09320	COG0840	transmembrane signaling receptor activity
ITG10_09330	COG1285	pathogenesis
ITG10_09335	COG1509	lysine 2,3-aminomutase activity
ITG10_09340	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ITG10_09350	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ITG10_09355	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ITG10_09360	COG1053	succinate dehydrogenase
ITG10_09365	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ITG10_09375	COG0840	transmembrane signaling receptor activity
ITG10_09380	COG0490	domain, Protein
ITG10_09380	COG0471	metal ion transport
ITG10_09385	COG0688	phosphatidylethanolamine metabolic process
ITG10_09390	COG1162	GTPase activity
ITG10_09480	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ITG10_09485	COG0802	atpase or kinase
ITG10_09490	COG0860	N-Acetylmuramoyl-L-alanine amidase
ITG10_09495	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ITG10_09500	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ITG10_09505	COG1923	regulation of RNA biosynthetic process
ITG10_09510	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ITG10_09515	COG0330	HflC and HflK could
ITG10_09520	COG0330	HflC and HflK could
ITG10_09525	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ITG10_09530	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ITG10_09535	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ITG10_09540	COG0402	S-adenosylhomocysteine deaminase activity
ITG10_09545	COG0557	exoribonuclease II activity
ITG10_09550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ITG10_09565	COG0359	binds to the 23S rRNA
ITG10_09580	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ITG10_09590	COG0432	Pfam Uncharacterised protein family UPF0047
ITG10_09595	COG0166	Belongs to the GPI family
ITG10_09605	COG0735	belongs to the Fur family
ITG10_09625	COG3385	transposase activity
ITG10_09635	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ITG10_09640	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ITG10_09645	COG0175	sulfate reduction
ITG10_09730	COG0527	aspartate kinase activity
ITG10_09735	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ITG10_09750	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ITG10_09760	COG2197	response regulator
ITG10_09765	COG0629	single-stranded DNA binding
ITG10_09770	COG2200	EAL domain
ITG10_09770	COG2199	diguanylate cyclase activity
ITG10_09795	COG3267	Type II secretory pathway component ExeA
ITG10_09795	COG3409	Peptidoglycan-binding domain 1 protein
ITG10_09805	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ITG10_09810	COG1459	type II secretion system
ITG10_09820	COG2165	general secretion pathway protein
ITG10_09825	COG2165	general secretion pathway protein
ITG10_09855	COG1077	Cell shape determining protein MreB Mrl
ITG10_09860	COG1792	Involved in formation and maintenance of cell shape
ITG10_09865	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ITG10_09870	COG0424	maF-like protein
ITG10_09885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ITG10_09890	COG0312	modulator of DNA gyrase
ITG10_09895	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ITG10_09900	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ITG10_09915	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ITG10_09920	COG0589	response to stress
ITG10_09930	COG2358	TRAP transporter, solute receptor (TAXI family
ITG10_09935	COG1438	arginine binding
ITG10_09940	COG0039	L-malate dehydrogenase activity
ITG10_09955	COG0142	geranyltranstransferase activity
ITG10_09960	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ITG10_09965	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ITG10_09970	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ITG10_09975	COG2966	Psort location CytoplasmicMembrane, score
ITG10_09980	COG3610	response to peptide
ITG10_09990	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ITG10_09995	COG2967	ApaG domain
ITG10_10000	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ITG10_10005	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ITG10_10010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ITG10_10015	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ITG10_10020	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ITG10_10035	COG0066	3-isopropylmalate dehydratase activity
ITG10_10045	COG0473	3-isopropylmalate dehydrogenase activity
ITG10_10050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ITG10_10090	COG1022	Amp-dependent synthetase and ligase
ITG10_10095	COG0028	Belongs to the TPP enzyme family
ITG10_10105	COG3706	GGDEF domain
ITG10_10115	COG0469	pyruvate kinase activity
ITG10_10120	COG1349	DNA-binding transcription factor activity
ITG10_10125	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ITG10_10130	COG2873	o-acetylhomoserine
ITG10_10145	COG0358	DNA primase activity
ITG10_10150	COG1610	YqeY-like protein
ITG10_10155	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ITG10_10160	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ITG10_10165	COG0596	Alpha beta hydrolase
ITG10_10170	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ITG10_10175	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ITG10_10185	COG1968	undecaprenyl-diphosphatase activity
ITG10_10195	COG3267	Type II secretory pathway component ExeA
ITG10_10195	COG3409	Peptidoglycan-binding domain 1 protein
ITG10_10205	COG4991	sh3 domain protein
ITG10_10210	COG0306	phosphate transporter
ITG10_10215	COG1392	Phosphate transport regulator
ITG10_10220	COG3025	triphosphatase activity
ITG10_10240	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ITG10_10245	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ITG10_10245	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ITG10_10250	COG1538	Outer membrane efflux protein
ITG10_10255	COG0494	nUDIX hydrolase
ITG10_10260	COG3151	Protein conserved in bacteria
ITG10_10270	COG3150	esterase
ITG10_10285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ITG10_10290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ITG10_10295	COG3105	Protein conserved in bacteria
ITG10_10300	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ITG10_10305	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ITG10_10310	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ITG10_10315	COG0723	plastoquinol--plastocyanin reductase activity
ITG10_10320	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ITG10_10325	COG2857	Cytochrome c1
ITG10_10330	COG0625	glutathione transferase activity
ITG10_10335	COG2969	positive regulation of protein catabolic process
ITG10_10345	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ITG10_10360	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ITG10_10370	COG0275	rRNA processing
ITG10_10375	COG3116	cell division
ITG10_10380	COG0768	penicillin binding
ITG10_10385	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ITG10_10390	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ITG10_10395	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ITG10_10400	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ITG10_10405	COG0772	Belongs to the SEDS family
ITG10_10410	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ITG10_10415	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ITG10_10420	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ITG10_10425	COG0849	cell division
ITG10_10430	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ITG10_10435	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ITG10_10440	COG0653	protein targeting
ITG10_10445	COG0494	nUDIX hydrolase
ITG10_10450	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ITG10_10455	COG0505	Belongs to the CarA family
ITG10_10460	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ITG10_10465	COG0730	response to heat
ITG10_10470	COG0583	DNA-binding transcription factor activity
ITG10_10485	COG2860	membrane
ITG10_10490	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ITG10_10500	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ITG10_10510	COG0493	'glutamate synthase
ITG10_10515	COG0067	glutamate synthase
ITG10_10515	COG0069	glutamate synthase activity
ITG10_10515	COG0070	glutamate synthase
ITG10_10525	COG0067	glutamate synthase
ITG10_10525	COG0069	glutamate synthase activity
ITG10_10525	COG0070	glutamate synthase
ITG10_10530	COG1242	4 iron, 4 sulfur cluster binding
ITG10_10535	COG2203	Gaf domain
ITG10_10535	COG3706	GGDEF domain
ITG10_10535	COG4251	negative regulation of phosphorylation
ITG10_10535	COG5001	Diguanylate cyclase
ITG10_10540	COG0784	Response regulator, receiver
ITG10_10540	COG2198	Histidine kinase
ITG10_10540	COG5002	protein histidine kinase activity
ITG10_10550	COG0745	RESPONSE REGULATOR receiver
ITG10_10555	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ITG10_10570	COG0083	homoserine kinase activity
ITG10_10575	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ITG10_10585	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
ITG10_10590	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ITG10_10595	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ITG10_10610	COG1115	amino acid carrier protein
ITG10_10615	COG3022	response to hydroperoxide
ITG10_10620	COG0513	Belongs to the DEAD box helicase family
ITG10_10625	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ITG10_10635	COG0716	FMN binding
ITG10_10640	COG4974	Belongs to the 'phage' integrase family
ITG10_10645	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ITG10_10650	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ITG10_10660	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ITG10_10685	COG0494	nUDIX hydrolase
ITG10_10695	COG0730	response to heat
ITG10_10700	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ITG10_10705	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ITG10_10715	COG1283	sodium-dependent phosphate transmembrane transporter activity
ITG10_10720	COG0583	DNA-binding transcription factor activity
ITG10_10725	COG0640	Transcriptional regulator
ITG10_10730	COG0268	Binds directly to 16S ribosomal RNA
ITG10_10735	COG0728	peptidoglycan biosynthetic process
ITG10_10740	COG0196	riboflavin kinase activity
ITG10_10745	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ITG10_10755	COG1047	Peptidyl-prolyl cis-trans
ITG10_10760	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ITG10_10765	COG3279	Response regulator of the LytR AlgR family
ITG10_10770	COG3275	phosphorelay sensor kinase activity
ITG10_10775	COG1966	Carbon starvation protein
ITG10_10785	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ITG10_10790	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ITG10_10795	COG2971	BadF BadG BcrA BcrD
ITG10_10805	COG1737	Transcriptional regulator
ITG10_10815	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ITG10_10820	COG0287	Prephenate dehydrogenase
ITG10_10820	COG1605	Chorismate mutase
ITG10_10825	COG0739	heme binding
ITG10_10835	COG0488	(ABC) transporter
ITG10_10845	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
ITG10_10850	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
ITG10_10860	COG0077	Prephenate dehydratase
ITG10_10860	COG1605	Chorismate mutase
ITG10_10865	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ITG10_10870	COG0741	lytic transglycosylase activity
ITG10_10875	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ITG10_10880	COG0564	pseudouridine synthase activity
ITG10_10885	COG1496	oxidoreductase activity
ITG10_10925	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
ITG10_10940	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ITG10_10945	COG0826	peptidase U32
ITG10_10950	COG2974	May be involved in recombination
ITG10_10955	COG0745	RESPONSE REGULATOR receiver
ITG10_10960	COG5002	protein histidine kinase activity
ITG10_10970	COG0248	Ppx GppA phosphatase
ITG10_10975	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ITG10_10985	COG0581	inorganic phosphate transmembrane transporter activity
ITG10_10990	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ITG10_10995	COG0704	Plays a role in the regulation of phosphate uptake
ITG10_11015	COG3142	Participates in the control of copper homeostasis
ITG10_11020	COG0450	alkyl hydroperoxide reductase
ITG10_11025	COG0583	DNA-binding transcription factor activity
ITG10_11040	COG0517	IMP dehydrogenase activity
ITG10_11045	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ITG10_11050	COG0343	queuine tRNA-ribosyltransferase activity
ITG10_11055	COG1862	Preprotein translocase
ITG10_11060	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ITG10_11065	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ITG10_11070	COG0483	inositol monophosphate 1-phosphatase activity
ITG10_11075	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ITG10_11080	COG1959	2 iron, 2 sulfur cluster binding
ITG10_11085	COG1104	cysteine desulfurase activity
ITG10_11090	COG0822	iron-sulfur transferase activity
ITG10_11100	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ITG10_11105	COG0443	Heat shock 70 kDa protein
ITG10_11115	COG2975	iron-sulfur cluster assembly
ITG10_11120	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ITG10_11125	COG0105	UTP biosynthetic process
ITG10_11130	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ITG10_11140	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ITG10_11145	COG0124	histidyl-tRNA synthetase
ITG10_11150	COG2976	Protein conserved in bacteria
ITG10_11155	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ITG10_11160	COG1160	GTP binding
ITG10_11170	COG3706	GGDEF domain
ITG10_11210	COG0831	urea catabolic process
ITG10_11215	COG0832	Belongs to the urease beta subunit family
ITG10_11220	COG0804	urea catabolic process
ITG10_11225	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
ITG10_11240	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ITG10_11245	COG1570	exodeoxyribonuclease VII activity
ITG10_11250	COG0516	GMP reductase activity
ITG10_11250	COG0517	IMP dehydrogenase activity
ITG10_11255	COG0519	Catalyzes the synthesis of GMP from XMP
ITG10_11255	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ITG10_11265	COG1757	Na H antiporter
ITG10_11275	COG1584	GPR1 FUN34 yaaH family protein
ITG10_11280	COG1115	amino acid carrier protein
ITG10_11290	COG0204	Acyl-transferase
ITG10_11300	COG2264	protein methyltransferase activity
ITG10_11315	COG0189	ligase activity
ITG10_11315	COG4067	protein conserved in archaea
ITG10_11340	COG1028	Short-chain dehydrogenase reductase Sdr
ITG10_11355	COG1028	Short-chain dehydrogenase reductase Sdr
ITG10_11375	COG1484	DNA-dependent DNA replication
ITG10_11390	COG1396	sequence-specific DNA binding
ITG10_11395	COG3550	peptidyl-serine autophosphorylation
ITG10_11410	COG1396	sequence-specific DNA binding
ITG10_11430	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ITG10_11455	COG0582	viral genome integration into host DNA
ITG10_11470	COG2867	negative regulation of translational initiation
ITG10_11475	COG2914	Belongs to the UPF0125 (RnfH) family
ITG10_11480	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ITG10_11485	COG0497	DNA recombination
ITG10_11490	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ITG10_11495	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ITG10_11515	COG0443	Heat shock 70 kDa protein
ITG10_11520	COG0484	heat shock protein binding
ITG10_11550	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ITG10_11555	COG1253	flavin adenine dinucleotide binding
ITG10_11570	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ITG10_11570	COG0047	phosphoribosylformylglycinamidine synthase activity
ITG10_11580	COG2171	N-acyltransferase activity
ITG10_11585	COG2095	MarC family integral membrane protein
ITG10_11600	COG3141	response to X-ray
ITG10_11615	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ITG10_11620	COG1074	ATP-dependent DNA helicase activity
ITG10_11625	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ITG10_11635	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ITG10_11635	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ITG10_11645	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ITG10_11650	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ITG10_11655	COG2166	iron-sulfur cluster assembly
ITG10_11665	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ITG10_11670	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ITG10_11675	COG3248	Nucleoside-binding outer membrane protein
ITG10_11690	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ITG10_11700	COG2813	Specifically methylates the guanine in position
ITG10_11705	COG0271	Belongs to the BolA IbaG family
ITG10_11710	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ITG10_11715	COG1805	sodium ion transport
ITG10_11725	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ITG10_11730	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ITG10_11735	COG2871	sodium ion transport
ITG10_11740	COG1477	protein flavinylation
ITG10_11745	COG2991	Protein conserved in bacteria
ITG10_11755	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ITG10_11775	COG0733	neurotransmitter:sodium symporter activity
ITG10_11780	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ITG10_11785	COG0321	lipoyl(octanoyl) transferase activity
ITG10_11795	COG1686	Belongs to the peptidase S11 family
ITG10_11800	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ITG10_11805	COG0772	Belongs to the SEDS family
ITG10_11810	COG0768	penicillin binding
ITG10_11815	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ITG10_11820	COG0799	negative regulation of ribosome biogenesis
ITG10_11825	COG1466	dna polymerase III delta subunit
ITG10_11830	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
ITG10_11835	COG0495	leucyl-tRNA aminoacylation
ITG10_11840	COG2888	peptidyl-tyrosine sulfation
ITG10_11845	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ITG10_11850	COG4535	Mg2 and Co2 transporter CorC
ITG10_11855	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ITG10_11860	COG1702	phosphate starvation-inducible protein PhoH
ITG10_11865	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ITG10_11870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ITG10_11875	COG2706	6-phosphogluconolactonase activity
ITG10_11950	COG0193	aminoacyl-tRNA hydrolase activity
ITG10_11955	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ITG10_11960	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ITG10_11965	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ITG10_11970	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ITG10_11975	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ITG10_11980	COG2890	protein-(glutamine-N5) methyltransferase activity
ITG10_11985	COG3094	Invasion gene expression up-regulator, SirB
ITG10_11990	COG2912	Transglutaminase-like superfamily
ITG10_11995	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ITG10_12010	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ITG10_12015	COG1187	pseudouridine synthase activity
ITG10_12020	COG2840	Smr protein MutS2
ITG10_12060	COG2608	mercury ion transmembrane transporter activity
ITG10_12060	COG2217	Heavy metal translocating P-type atpase
ITG10_12080	COG1028	Short-chain dehydrogenase reductase Sdr
ITG10_12115	COG2986	histidine ammonia-lyase
ITG10_12120	COG1216	Glycosyl transferase, family 2
ITG10_12140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ITG10_12145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ITG10_12195	COG3344	reverse transcriptase
ITG10_12210	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
ITG10_12215	COG0784	Response regulator, receiver
ITG10_12215	COG0835	chemotaxis
ITG10_12220	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ITG10_12225	COG1815	bacterial-type flagellum-dependent cell motility
ITG10_12240	COG1749	Flagellar hook protein flgE
ITG10_12245	COG4787	bacterial-type flagellum-dependent cell motility
ITG10_12255	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ITG10_12260	COG1706	bacterial-type flagellum-dependent cell motility
ITG10_12265	COG1705	Flagellar rod assembly protein muramidase FlgJ
ITG10_12265	COG3951	Flagellar rod assembly protein muramidase FlgJ
ITG10_12280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ITG10_12285	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ITG10_12295	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ITG10_12305	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ITG10_12315	COG1516	flagellar protein fliS
ITG10_12335	COG1677	Flagellar hook-basal body complex protein FliE
ITG10_12345	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ITG10_12395	COG1987	bacterial-type flagellum assembly
ITG10_12400	COG1684	flagellar biosynthetic protein fliR
ITG10_12435	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ITG10_12440	COG2198	Histidine kinase
ITG10_12440	COG0643	Histidine kinase
ITG10_12440	COG0784	Response regulator, receiver
ITG10_12445	COG2201	protein-glutamate methylesterase activity
ITG10_12450	COG1192	Involved in chromosome partitioning
ITG10_12460	COG0835	chemotaxis
ITG10_12470	COG4133	protoheme IX ABC transporter activity
ITG10_12475	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ITG10_12480	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ITG10_12485	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ITG10_12490	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
ITG10_12495	COG1138	Cytochrome C-type biogenesis protein
ITG10_12500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ITG10_12505	COG3088	subunit of a heme lyase
ITG10_12505	COG4235	cytochrome complex assembly
ITG10_12510	COG3088	subunit of a heme lyase
ITG10_12510	COG4235	cytochrome complex assembly
ITG10_12515	COG2853	Lipoprotein
ITG10_12520	COG2067	long-chain fatty acid transport protein
ITG10_12540	COG0183	Belongs to the thiolase family
ITG10_12545	COG1024	Enoyl-CoA hydratase
ITG10_12545	COG1250	3-hydroxyacyl-CoA dehydrogenase
ITG10_12555	COG2062	phosphohistidine phosphatase, SixA
ITG10_12565	COG2890	protein-(glutamine-N5) methyltransferase activity
ITG10_12570	COG1280	lysine exporter protein (LysE YggA)
ITG10_12575	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ITG10_12595	COG1175	transmembrane transport
ITG10_12605	COG3842	ATPase activity
ITG10_12610	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ITG10_12615	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ITG10_12615	COG2070	2-Nitropropane dioxygenase
ITG10_12645	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ITG10_12650	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ITG10_12655	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ITG10_12665	COG2204	response regulator
ITG10_12680	COG0544	peptidyl-prolyl cis-trans isomerase activity
ITG10_12685	COG0740	serine-type endopeptidase activity
ITG10_12690	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ITG10_12695	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ITG10_12700	COG0776	regulation of translation
ITG10_12705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ITG10_12710	COG1555	photosystem II stabilization
ITG10_12725	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ITG10_12730	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ITG10_12735	COG0436	Aminotransferase
ITG10_12740	COG1169	isochorismate synthase
ITG10_12745	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ITG10_12750	COG2267	carboxylic ester hydrolase activity
ITG10_12755	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ITG10_12775	COG2855	membrane
ITG10_12845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ITG10_12865	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ITG10_12870	COG1522	sequence-specific DNA binding
ITG10_12880	COG1946	Acyl-CoA thioesterase
ITG10_12885	COG3126	Type III secretion system lipoprotein chaperone (YscW)
ITG10_12930	COG1061	Type III restriction enzyme res subunit
ITG10_12965	COG1479	Protein of unknown function DUF262
ITG10_13000	COG0784	Response regulator, receiver
ITG10_13000	COG2205	protein histidine kinase activity
ITG10_13000	COG5002	protein histidine kinase activity
ITG10_13015	COG0210	DNA helicase
ITG10_13025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ITG10_13065	COG0328	RNA-DNA hybrid ribonuclease activity
ITG10_13065	COG3341	Caulimovirus viroplasmin
ITG10_13070	COG0438	transferase activity, transferring glycosyl groups
ITG10_13075	COG1216	Glycosyl transferase, family 2
ITG10_13075	COG0463	Glycosyl transferase, family 2
ITG10_13120	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ITG10_13140	COG2162	N-hydroxyarylamine O-acetyltransferase activity
ITG10_13150	COG0789	Transcriptional regulator
ITG10_13155	COG3394	polysaccharide catabolic process
ITG10_13160	COG1486	melibiose metabolic process
ITG10_13165	COG0583	DNA-binding transcription factor activity
ITG10_13195	COG3119	arylsulfatase activity
ITG10_13200	COG1609	Transcriptional regulator
ITG10_13215	COG2814	Major facilitator Superfamily
ITG10_13225	COG1760	l-serine dehydratase
ITG10_13230	COG1522	sequence-specific DNA binding
ITG10_13235	COG1280	lysine exporter protein (LysE YggA)
ITG10_13260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ITG10_13260	COG1263	PTS System
ITG10_13260	COG2190	(PTS) system
ITG10_13265	COG0583	DNA-binding transcription factor activity
ITG10_13285	COG3040	lipid binding
ITG10_13290	COG3038	cytochrome b561
ITG10_13305	COG0583	DNA-binding transcription factor activity
ITG10_13310	COG1309	transcriptional regulator
ITG10_13320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ITG10_13325	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ITG10_13330	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ITG10_13335	COG1845	cytochrome c oxidase, subunit III
ITG10_13340	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ITG10_13350	COG0681	Belongs to the peptidase S26 family
ITG10_13375	COG0583	DNA-binding transcription factor activity
ITG10_13380	COG0346	lactoylglutathione lyase activity
ITG10_13385	COG1902	pentaerythritol trinitrate reductase activity
ITG10_13390	COG0697	spore germination
ITG10_13415	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ITG10_13445	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ITG10_13445	COG0617	tRNA 3'-terminal CCA addition
ITG10_13445	COG0517	IMP dehydrogenase activity
ITG10_13455	COG2217	Heavy metal translocating P-type atpase
ITG10_13475	COG0537	adenosine 5'-monophosphoramidase activity
ITG10_13500	COG3150	esterase
ITG10_13505	COG1252	NADH dehydrogenase
ITG10_13520	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ITG10_13530	COG4591	ABC-type transport system involved in lipoprotein release permease component
ITG10_13535	COG1136	(ABC) transporter
ITG10_13540	COG4591	ABC-type transport system involved in lipoprotein release permease component
ITG10_13550	COG2333	competence protein COMEC
ITG10_13550	COG0658	competence protein
ITG10_13555	COG1132	(ABC) transporter
ITG10_13560	COG1663	tetraacyldisaccharide 4'-kinase activity
ITG10_13565	COG2835	tetraacyldisaccharide 4'-kinase activity
ITG10_13570	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ITG10_13575	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ITG10_13580	COG0539	negative regulation of cytoplasmic translation
ITG10_13585	COG0776	regulation of translation
ITG10_13590	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ITG10_13595	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ITG10_13600	COG0284	orotidine-5'-phosphate decarboxylase activity
ITG10_13615	COG0583	DNA-binding transcription factor activity
ITG10_13635	COG0686	Belongs to the AlaDH PNT family
ITG10_13640	COG1522	sequence-specific DNA binding
ITG10_13645	COG1674	ftsk spoiiie
ITG10_13650	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ITG10_13655	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ITG10_13660	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ITG10_13665	COG0745	RESPONSE REGULATOR receiver
ITG10_13675	COG0784	Response regulator, receiver
ITG10_13675	COG2205	protein histidine kinase activity
ITG10_13680	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ITG10_13685	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ITG10_13690	COG0156	8-amino-7-oxononanoate synthase activity
ITG10_13695	COG1073	alpha beta
ITG10_13695	COG2226	methyltransferase
ITG10_13710	COG0501	Belongs to the peptidase M48B family
ITG10_13715	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ITG10_13720	COG2915	High frequency lysogenization protein hflD homolog
ITG10_13735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ITG10_13740	COG2916	Histone family protein nucleoid-structuring protein H-NS
ITG10_13745	COG1757	Na H antiporter
ITG10_13765	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ITG10_13770	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ITG10_13770	COG0131	Imidazoleglycerol-phosphate dehydratase
ITG10_13775	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ITG10_13780	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ITG10_13785	COG0107	imidazoleglycerol-phosphate synthase activity
ITG10_13790	COG0140	phosphoribosyl-ATP diphosphatase activity
ITG10_13790	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ITG10_13795	COG3012	SEC-C Motif Domain Protein
ITG10_13800	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ITG10_13805	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ITG10_13810	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ITG10_13815	COG0215	cysteine-tRNA ligase activity
ITG10_13845	COG2116	formate transmembrane transporter activity
ITG10_13850	COG0390	transport system, permease component
ITG10_13855	COG4459	periplasmic nitrate reductase
ITG10_13860	COG3005	denitrification pathway
ITG10_13875	COG1227	inorganic diphosphatase activity
ITG10_13890	COG4172	Belongs to the ABC transporter superfamily
ITG10_13900	COG4171	peptide transport system, permease
ITG10_13905	COG4168	peptide transport system, permease
ITG10_13910	COG4166	transmembrane transport
ITG10_13915	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ITG10_13920	COG1842	Phage shock protein A
ITG10_13930	COG1983	PspC domain protein
ITG10_13935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ITG10_13940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ITG10_13950	COG2818	Glycosylase
ITG10_13965	COG0626	cystathionine gamma-synthase activity
ITG10_13975	COG0733	neurotransmitter:sodium symporter activity
ITG10_13985	COG0564	pseudouridine synthase activity
ITG10_13990	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ITG10_13990	COG0116	Belongs to the methyltransferase superfamily
ITG10_13995	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ITG10_14000	COG4136	ATPase activity
ITG10_14005	COG4135	transport system, permease component
ITG10_14010	COG4134	Bacterial extracellular solute-binding protein
ITG10_14020	COG3313	Fe-S protein
ITG10_14040	COG0513	Belongs to the DEAD box helicase family
ITG10_14045	COG1280	lysine exporter protein (LysE YggA)
ITG10_14055	COG2866	Carboxypeptidase
ITG10_14065	COG3005	denitrification pathway
ITG10_14070	COG0243	molybdopterin cofactor binding
ITG10_14090	COG4176	ABC-type proline glycine betaine transport system permease component
ITG10_14095	COG2113	Glycine betaine
ITG10_14100	COG2801	Transposase and inactivated derivatives
ITG10_14115	COG0583	DNA-binding transcription factor activity
ITG10_14125	COG2995	paraquat-inducible protein a
ITG10_14130	COG3008	intermembrane lipid transfer
ITG10_14130	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ITG10_14165	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ITG10_14175	COG0586	Pfam SNARE associated Golgi protein
ITG10_14185	COG0642	Histidine kinase
ITG10_14200	COG1061	Type III restriction enzyme res subunit
ITG10_14210	COG2814	Major facilitator Superfamily
ITG10_14225	COG0702	epimerase
ITG10_14230	COG1858	cytochrome C peroxidase
ITG10_14235	COG0534	Mate efflux family protein
ITG10_14255	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ITG10_14260	COG2885	chlorophyll binding
ITG10_14260	COG3047	cAMP biosynthetic process
ITG10_14280	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ITG10_14285	COG2985	domain, Protein
ITG10_14285	COG3273	potassium ion transport
ITG10_14290	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ITG10_14300	COG1737	Transcriptional regulator
ITG10_14305	COG0076	glutamate decarboxylase activity
ITG10_14315	COG2431	L-lysine efflux transmembrane transporter activity
ITG10_14325	COG3070	regulator of competence-specific genes
ITG10_14335	COG2204	response regulator
ITG10_14340	COG3852	Histidine kinase
ITG10_14350	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ITG10_14370	COG2258	MOSC domain
ITG10_14375	COG2176	DNA-directed DNA polymerase activity
ITG10_14390	COG1448	Aminotransferase
ITG10_14395	COG3437	response regulator, receiver
ITG10_14395	COG2770	Histidine kinase
ITG10_14405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ITG10_14415	COG0017	Asparaginyl-tRNA synthetase
ITG10_14420	COG0659	secondary active sulfate transmembrane transporter activity
ITG10_14430	COG0814	amino acid
ITG10_14435	COG1760	l-serine dehydratase
ITG10_14440	COG0814	amino acid
ITG10_14445	COG0494	nUDIX hydrolase
ITG10_14475	COG3106	COG3106 Predicted ATPase
ITG10_14490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ITG10_14505	COG0443	Heat shock 70 kDa protein
ITG10_14520	COG3706	GGDEF domain
ITG10_14535	COG3038	cytochrome b561
ITG10_14550	COG3710	Transcriptional regulator
ITG10_14590	COG3842	ATPase activity
ITG10_14595	COG3459	Glycosyltransferase 36 associated
ITG10_14610	COG1175	transmembrane transport
ITG10_14615	COG0395	ABC-type sugar transport system, permease component
ITG10_14630	COG1643	Atp-dependent helicase
ITG10_14675	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ITG10_14680	COG0072	phenylalanine-tRNA ligase activity
ITG10_14680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ITG10_14705	COG0596	Alpha beta hydrolase
ITG10_14760	COG0302	gtp cyclohydrolase
ITG10_14765	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ITG10_14770	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ITG10_14770	COG0302	gtp cyclohydrolase
ITG10_14785	COG1464	Belongs to the NlpA lipoprotein family
ITG10_14800	COG1522	sequence-specific DNA binding
ITG10_14805	COG2873	o-acetylhomoserine
ITG10_14840	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ITG10_14870	COG2205	protein histidine kinase activity
ITG10_14890	COG1342	Belongs to the UPF0251 family
ITG10_14920	COG0776	regulation of translation
ITG10_14950	COG2378	regulation of single-species biofilm formation
ITG10_14955	COG0840	transmembrane signaling receptor activity
ITG10_14965	COG0583	DNA-binding transcription factor activity
ITG10_14975	COG2175	clavaminate synthase activity
ITG10_14980	COG0488	(ABC) transporter
ITG10_14985	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ITG10_15000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ITG10_15010	COG2988	succinylglutamate desuccinylase activity
ITG10_15015	COG0523	cobalamin synthesis protein
ITG10_15025	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ITG10_15035	COG0776	regulation of translation
ITG10_15055	COG0500	methyltransferase
ITG10_15060	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ITG10_15065	COG0295	cytidine deaminase activity
ITG10_15070	COG1346	cytolysis
ITG10_15080	COG2925	Exonuclease
ITG10_15125	COG3568	Endonuclease Exonuclease Phosphatase
ITG10_15130	COG3122	Protein conserved in bacteria
ITG10_15155	COG4989	oxidoreductase activity
ITG10_15165	COG1823	symporter activity
ITG10_15170	COG0702	epimerase
ITG10_15175	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ITG10_15180	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ITG10_15185	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ITG10_15205	COG2988	succinylglutamate desuccinylase activity
ITG10_15210	COG4139	cobalamin transport
ITG10_15215	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
ITG10_15235	COG0601	transmembrane transport
ITG10_15240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ITG10_15265	COG1247	-acetyltransferase
ITG10_15285	COG2814	Major facilitator Superfamily
ITG10_15290	COG0583	DNA-binding transcription factor activity
ITG10_15300	COG1451	nucleotide metabolic process
ITG10_15310	COG3063	Type IV pilus biogenesis stability protein PilW
ITG10_15315	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ITG10_15330	COG2195	Cleaves the N-terminal amino acid of tripeptides
ITG10_15335	COG3706	GGDEF domain
ITG10_15385	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ITG10_15415	COG3469	chitinase activity
ITG10_15445	COG0454	-acetyltransferase
ITG10_15470	COG0346	lactoylglutathione lyase activity
ITG10_15540	COG1120	ATPase activity
ITG10_15600	COG0584	glycerophosphoryl diester phosphodiesterase
ITG10_15715	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ITG10_15725	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ITG10_15725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ITG10_15835	COG0583	DNA-binding transcription factor activity
ITG10_15860	COG0653	protein targeting
ITG10_15865	COG0546	phosphoglycolate phosphatase activity
ITG10_15930	COG1126	abc transporter atp-binding protein
ITG10_16050	COG0583	DNA-binding transcription factor activity
ITG10_16075	COG1742	UPF0060 membrane protein
ITG10_16105	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ITG10_16135	COG4160	amino acid transport
ITG10_16140	COG4215	(ABC) transporter
ITG10_16145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ITG10_16150	COG1126	abc transporter atp-binding protein
ITG10_16165	COG0826	peptidase U32
ITG10_16205	COG1028	Short-chain dehydrogenase reductase Sdr
ITG10_16215	COG0546	phosphoglycolate phosphatase activity
ITG10_16220	COG0653	protein targeting
ITG10_16245	COG0583	DNA-binding transcription factor activity
ITG10_16250	COG2249	NAD(P)H dehydrogenase (quinone) activity
ITG10_16265	COG1619	proteins homologs of microcin C7 resistance protein MccF
ITG10_16280	COG1765	OsmC-like protein
ITG10_16295	COG0454	-acetyltransferase
ITG10_16360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ITG10_16360	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ITG10_16370	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ITG10_16390	COG4974	Belongs to the 'phage' integrase family
ITG10_16405	COG0517	IMP dehydrogenase activity
ITG10_16415	COG0110	maltose O-acetyltransferase activity
ITG10_16425	COG1187	pseudouridine synthase activity
ITG10_16465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ITG10_16475	COG0584	glycerophosphoryl diester phosphodiesterase
ITG10_16480	COG2271	Major facilitator Superfamily
ITG10_16500	COG4774	siderophore transport
ITG10_16520	COG4615	Cyclic peptide transporter
ITG10_16530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ITG10_16535	COG1120	ATPase activity
ITG10_16560	COG0589	response to stress
ITG10_16565	COG0415	Belongs to the DNA photolyase family
ITG10_16570	COG3046	protein related to deoxyribodipyrimidine photolyase
ITG10_16590	COG3547	Transposase (IS116 IS110 IS902 family)
ITG10_16595	COG0419	ATPase involved in DNA repair
ITG10_16600	COG0420	3'-5' exonuclease activity
ITG10_16605	COG0346	lactoylglutathione lyase activity
ITG10_16630	COG0454	-acetyltransferase
ITG10_16635	COG2199	diguanylate cyclase activity
ITG10_16645	COG4771	TonB-dependent receptor
ITG10_16655	COG3469	chitinase activity
ITG10_16705	COG2204	response regulator
ITG10_16715	COG4175	Glycine betaine
ITG10_16715	COG3448	diguanylate cyclase activity
ITG10_16720	COG4176	ABC-type proline glycine betaine transport system permease component
ITG10_16740	COG2885	chlorophyll binding
ITG10_16750	COG1793	dna ligase
ITG10_16755	COG0534	Mate efflux family protein
ITG10_16760	COG0307	riboflavin synthase, alpha
ITG10_16770	COG3001	Fructosamine kinase
ITG10_16780	COG0791	NLP P60 protein
ITG10_16785	COG0840	transmembrane signaling receptor activity
ITG10_16795	COG3148	PFAM DTW domain containing protein
ITG10_16800	COG1940	carbohydrate kinase activity
ITG10_16815	COG0303	'Molybdopterin
ITG10_16820	COG0746	molybdenum cofactor guanylyltransferase activity
ITG10_16825	COG3842	ATPase activity
ITG10_16830	COG4662	Binding-protein-dependent transport system inner membrane component
ITG10_16845	COG4191	Histidine kinase
ITG10_16865	COG0488	(ABC) transporter
ITG10_16875	COG4890	Cyd operon protein YbgT
ITG10_16880	COG1294	oxidase, subunit
ITG10_16885	COG1271	oxidase subunit
ITG10_16900	COG3220	belongs to the UPF0276 family
ITG10_16915	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ITG10_16935	COG3381	protein complex oligomerization
ITG10_16945	COG0243	molybdopterin cofactor binding
ITG10_16945	COG3383	formate dehydrogenase (NAD+) activity
ITG10_16950	COG0437	4 iron, 4 sulfur cluster binding
ITG10_16965	COG0004	ammonium transporteR
ITG10_16970	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ITG10_16980	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ITG10_16990	COG1177	transmembrane transport
ITG10_17000	COG3842	ATPase activity
ITG10_17020	COG0037	tRNA processing
ITG10_17025	COG0589	response to stress
ITG10_17030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ITG10_17045	COG2217	Heavy metal translocating P-type atpase
ITG10_17055	COG2010	Cytochrome c
ITG10_17070	COG3278	Belongs to the heme-copper respiratory oxidase family
ITG10_17085	COG2205	protein histidine kinase activity
ITG10_17085	COG0784	Response regulator, receiver
ITG10_17130	COG4128	Pfam Zonular occludens toxin
ITG10_17140	COG0464	growth
ITG10_17180	COG3120	sequence-specific DNA binding
ITG10_17185	COG1067	ATP-dependent peptidase activity
ITG10_17205	COG0488	(ABC) transporter
ITG10_17215	COG0116	Belongs to the methyltransferase superfamily
ITG10_17215	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ITG10_17225	COG0167	dihydroorotate dehydrogenase activity
ITG10_17230	COG2902	Dehydrogenase
ITG10_17240	COG0308	aminopeptidase N
ITG10_17255	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
ITG10_17260	COG1956	GAF domain-containing protein
ITG10_17265	COG1132	(ABC) transporter
ITG10_17270	COG2995	paraquat-inducible protein a
ITG10_17275	COG3008	intermembrane lipid transfer
ITG10_17280	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ITG10_17280	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ITG10_17285	COG2996	Protein conserved in bacteria
ITG10_17300	COG0574	Belongs to the PEP-utilizing enzyme family
ITG10_17300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ITG10_17305	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ITG10_17310	COG1666	GTP binding
ITG10_17320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ITG10_17325	COG4597	amino acid ABC transporter
ITG10_17330	COG0765	amino acid transport
ITG10_17335	COG1126	abc transporter atp-binding protein
ITG10_17340	COG0670	Belongs to the BI1 family
ITG10_17345	COG2920	part of a sulfur-relay system
ITG10_17350	COG1254	Belongs to the acylphosphatase family
ITG10_17355	COG0840	transmembrane signaling receptor activity
ITG10_17380	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ITG10_17390	COG0402	S-adenosylhomocysteine deaminase activity
ITG10_17400	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ITG10_17405	COG0789	Transcriptional regulator
ITG10_17420	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ITG10_17445	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
ITG10_17450	COG4266	Belongs to the allantoicase family
ITG10_17470	COG2252	PERMEase
ITG10_17495	COG0402	S-adenosylhomocysteine deaminase activity
ITG10_17520	COG2084	Dehydrogenase
ITG10_17525	COG3622	Belongs to the hyi family
ITG10_17530	COG3960	tartronate-semialdehyde synthase activity
ITG10_17535	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ITG10_17545	COG1846	Transcriptional regulator
ITG10_17605	COG4964	Belongs to the GSP D family
ITG10_17695	COG1067	ATP-dependent peptidase activity
ITG10_17705	COG4172	Belongs to the ABC transporter superfamily
ITG10_17710	COG1609	Transcriptional regulator
ITG10_17720	COG2017	converts alpha-aldose to the beta-anomer
ITG10_17725	COG3459	Glycosyltransferase 36 associated
ITG10_17730	COG3842	ATPase activity
ITG10_17735	COG2723	6-phospho-beta-galactosidase activity
ITG10_17740	COG0395	ABC-type sugar transport system, permease component
ITG10_17760	COG0840	transmembrane signaling receptor activity
ITG10_17770	COG1505	serine-type exopeptidase activity
ITG10_17775	COG0583	DNA-binding transcription factor activity
ITG10_17780	COG1620	l-lactate permease
ITG10_17785	COG1304	FMN binding
ITG10_17805	COG0747	negative chemotaxis
ITG10_17810	COG4172	Belongs to the ABC transporter superfamily
ITG10_17820	COG0534	Mate efflux family protein
ITG10_17825	COG2207	Transcriptional regulator
ITG10_17825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ITG10_17830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ITG10_17840	COG1054	Belongs to the UPF0176 family
ITG10_17855	COG0745	RESPONSE REGULATOR receiver
ITG10_17875	COG2271	Major facilitator Superfamily
ITG10_17880	COG3851	Histidine kinase
ITG10_17885	COG2197	response regulator
ITG10_17915	COG1741	Belongs to the pirin family
ITG10_17920	COG3123	guanosine phosphorylase activity
ITG10_17935	COG0596	Alpha beta hydrolase
ITG10_17980	COG3788	relative of glutathione S-transferase, MAPEG superfamily
ITG10_17985	COG0700	Nucleoside recognition
ITG10_17990	COG3366	ferrous iron transmembrane transporter activity
ITG10_18005	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ITG10_18015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ITG10_18020	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ITG10_18040	COG0363	glucosamine-6-phosphate deaminase activity
ITG10_18045	COG3722	fumarate hydratase activity
ITG10_18050	COG0246	Mannitol dehydrogenase
ITG10_18055	COG2213	PTS system mannitol-specific
ITG10_18055	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ITG10_18075	COG0446	pyridine nucleotide-disulphide oxidoreductase
ITG10_18080	COG0786	glutamate:sodium symporter activity
ITG10_18095	COG1942	4-Oxalocrotonate Tautomerase
ITG10_18105	COG1595	DNA-templated transcription, initiation
ITG10_18110	COG3806	Anti-sigma factor
ITG10_18120	COG0415	Belongs to the DNA photolyase family
ITG10_18130	COG4221	oxidoreductase activity
ITG10_18145	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ITG10_18170	COG0724	RNA recognition motif
ITG10_18180	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ITG10_18195	COG1263	PTS System
ITG10_18195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ITG10_18200	COG2205	protein histidine kinase activity
ITG10_18215	COG1028	Short-chain dehydrogenase reductase Sdr
ITG10_18220	COG2814	Major facilitator Superfamily
ITG10_18225	COG1902	pentaerythritol trinitrate reductase activity
ITG10_18240	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ITG10_18245	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ITG10_18255	COG0612	Peptidase, M16
ITG10_18260	COG0612	Peptidase, M16
ITG10_18265	COG3279	Response regulator of the LytR AlgR family
ITG10_18270	COG3275	phosphorelay sensor kinase activity
ITG10_18290	COG1136	(ABC) transporter
ITG10_18310	COG0583	DNA-binding transcription factor activity
ITG10_18315	COG2084	Dehydrogenase
ITG10_18330	COG0217	transcriptional regulatory protein
ITG10_18345	COG3186	Phenylalanine-4-hydroxylase
ITG10_18350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ITG10_18365	COG1175	transmembrane transport
ITG10_18375	COG3842	ATPase activity
ITG10_18380	COG1234	tRNA 3'-trailer cleavage
ITG10_18385	COG0483	inositol monophosphate 1-phosphatase activity
ITG10_18390	COG1609	Transcriptional regulator
ITG10_18395	COG0625	glutathione transferase activity
ITG10_18405	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ITG10_18420	COG3842	ATPase activity
ITG10_18455	COG0765	amino acid transport
ITG10_18470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ITG10_18485	COG4221	oxidoreductase activity
ITG10_18495	COG4999	Histidine kinase
ITG10_18495	COG3850	Histidine kinase
ITG10_18495	COG3437	response regulator, receiver
ITG10_18495	COG2205	protein histidine kinase activity
ITG10_18505	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ITG10_18505	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
ITG10_18545	COG2801	Transposase and inactivated derivatives
ITG10_18550	COG2963	transposase activity
ITG10_18560	COG1444	tRNA N-acetyltransferase activity
ITG10_18600	COG0259	pyridoxamine-phosphate oxidase activity
ITG10_18615	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ITG10_18640	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ITG10_18675	COG1132	(ABC) transporter
ITG10_18700	COG2194	sulfuric ester hydrolase activity
ITG10_18730	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ITG10_18740	COG4145	pantothenate transmembrane transporter activity
ITG10_18745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ITG10_18750	COG0800	Aldolase
ITG10_18765	COG2204	response regulator
ITG10_18780	COG0579	oxidoreductase
ITG10_18800	COG2205	protein histidine kinase activity
ITG10_18805	COG0745	RESPONSE REGULATOR receiver
ITG10_18825	COG1309	transcriptional regulator
ITG10_18830	COG1012	belongs to the aldehyde dehydrogenase family
ITG10_18850	COG0517	IMP dehydrogenase activity
ITG10_18850	COG4175	Glycine betaine
ITG10_18855	COG1846	Transcriptional regulator
ITG10_18895	COG0641	radical SAM
ITG10_18900	COG1309	transcriptional regulator
ITG10_18910	COG0456	acetyltransferase
ITG10_18930	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ITG10_18935	COG0800	Aldolase
ITG10_18940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ITG10_18945	COG1263	PTS System
ITG10_18945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ITG10_18955	COG2188	Transcriptional regulator
ITG10_18965	COG2207	Transcriptional regulator
ITG10_18990	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ITG10_19005	COG2207	Transcriptional regulator
ITG10_19010	COG2814	Major facilitator Superfamily
ITG10_19020	COG0604	alcohol dehydrogenase
ITG10_19020	COG3321	synthase
ITG10_19020	COG1028	Short-chain dehydrogenase reductase Sdr
ITG10_19075	COG1609	Transcriptional regulator
ITG10_19080	COG0129	dihydroxy-acid dehydratase activity
ITG10_19085	COG3265	gluconokinase activity
ITG10_19090	COG1263	PTS System
ITG10_19090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ITG10_19095	COG2723	6-phospho-beta-galactosidase activity
ITG10_19100	COG0800	Aldolase
ITG10_19110	COG0300	oxidoreductase activity
ITG10_19120	COG0534	Mate efflux family protein
ITG10_19125	COG0583	DNA-binding transcription factor activity
ITG10_19130	COG2015	COG2015, Alkyl sulfatase and related hydrolases
ITG10_19145	COG0346	lactoylglutathione lyase activity
ITG10_19160	COG2723	6-phospho-beta-galactosidase activity
ITG10_19165	COG1609	Transcriptional regulator
ITG10_19170	COG0110	maltose O-acetyltransferase activity
ITG10_19175	COG2814	Major facilitator Superfamily
ITG10_19180	COG0583	DNA-binding transcription factor activity
ITG10_19185	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ITG10_19190	COG1301	dicarboxylic acid transport
ITG10_19205	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ITG10_19215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ITG10_19240	COG0583	DNA-binding transcription factor activity
ITG10_19250	COG1028	Short-chain dehydrogenase reductase Sdr
ITG10_19255	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ITG10_19260	COG1349	DNA-binding transcription factor activity
ITG10_19265	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ITG10_19270	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ITG10_19280	COG0583	DNA-binding transcription factor activity
ITG10_19285	COG0798	PFAM Bile acid sodium symporter
ITG10_19300	COG1309	transcriptional regulator
ITG10_19305	COG0561	phosphatase activity
ITG10_19320	COG3214	Protein conserved in bacteria
ITG10_19325	COG0583	DNA-binding transcription factor activity
ITG10_19390	COG0561	phosphatase activity
ITG10_19395	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ITG10_19400	COG3623	hexulose-6-phosphate isomerase
ITG10_19410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ITG10_19415	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ITG10_19435	COG3623	hexulose-6-phosphate isomerase
ITG10_19440	COG1414	Transcriptional regulator
ITG10_19445	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ITG10_19460	COG0561	phosphatase activity
ITG10_19470	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ITG10_19475	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ITG10_19480	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ITG10_19490	COG1929	Belongs to the glycerate kinase type-1 family
ITG10_19495	COG0753	catalase activity
ITG10_19500	COG4667	esterase of the alpha-beta hydrolase superfamily
ITG10_19505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ITG10_19510	COG3615	Tellurite resistance protein tehB
ITG10_19515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ITG10_19520	COG0204	Acyl-transferase
ITG10_19540	COG4580	involved in the transport of maltose and maltodextrins
ITG10_19580	COG3258	Cytochrome c
ITG10_19620	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ITG10_19625	COG1162	GTPase activity
ITG10_19635	COG1999	signal sequence binding
ITG10_19650	COG2909	trisaccharide binding
ITG10_19655	COG0058	SHG alpha-glucan phosphorylase activity
ITG10_19660	COG1640	4-alpha-glucanotransferase
ITG10_19665	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ITG10_19680	COG1122	ATPase activity
ITG10_19685	COG4720	Psort location CytoplasmicMembrane, score
ITG10_19690	COG1566	PFAM secretion protein HlyD family protein
ITG10_19720	COG0813	purine-nucleoside phosphorylase activity
ITG10_19725	COG1388	LysM domain
ITG10_19725	COG1376	ErfK ybiS ycfS ynhG family protein
ITG10_19735	COG0513	Belongs to the DEAD box helicase family
ITG10_19740	COG3240	lipase activity
ITG10_19745	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ITG10_19760	COG4771	TonB-dependent receptor
ITG10_19795	COG0573	inorganic phosphate transmembrane transporter activity
ITG10_19800	COG0581	inorganic phosphate transmembrane transporter activity
ITG10_19805	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ITG10_19825	COG2304	oxidoreductase activity
ITG10_19830	COG2304	oxidoreductase activity
ITG10_19845	COG0714	Associated with various cellular activities
ITG10_19850	COG0840	transmembrane signaling receptor activity
ITG10_19860	COG3842	ATPase activity
ITG10_19870	COG1175	transmembrane transport
ITG10_19875	COG3833	ABC-type maltose transport systems, permease component
ITG10_19890	COG4166	transmembrane transport
ITG10_19920	COG0577	efflux transmembrane transporter activity
ITG10_19925	COG1136	(ABC) transporter
ITG10_19940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ITG10_19945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ITG10_19965	COG3706	GGDEF domain
ITG10_19985	COG1028	Short-chain dehydrogenase reductase Sdr
ITG10_20005	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ITG10_20010	COG1904	glucuronate isomerase
ITG10_20030	COG4934	collagen metabolic process
ITG10_20060	COG1012	belongs to the aldehyde dehydrogenase family
ITG10_20065	COG1414	Transcriptional regulator
ITG10_20070	COG0280	phosphate acetyltransferase
ITG10_20075	COG0730	response to heat
ITG10_20105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ITG10_20110	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ITG10_20115	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ITG10_20120	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ITG10_20120	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ITG10_20135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ITG10_20160	COG0418	dihydroorotase activity
ITG10_20170	COG0633	Ferredoxin
ITG10_20170	COG3217	Mosc domain protein beta barrel domain protein
ITG10_20175	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ITG10_20230	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ITG10_20235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ITG10_20245	COG0848	biopolymer transport protein
ITG10_20250	COG0811	peptide transport
ITG10_20255	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ITG10_20265	COG3721	Heme iron utilization protein
ITG10_20270	COG0748	coenzyme F420 binding
ITG10_20275	COG2096	Adenosyltransferase
ITG10_20280	COG0784	Response regulator, receiver
ITG10_20280	COG0835	chemotaxis
ITG10_20285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ITG10_20290	COG0366	Alpha amylase catalytic
ITG10_20300	COG3314	Sporulation integral membrane protein YlbJ
ITG10_20325	COG0739	heme binding
ITG10_20330	COG5001	Diguanylate cyclase
ITG10_20335	COG0583	DNA-binding transcription factor activity
ITG10_20340	COG2814	Major facilitator Superfamily
ITG10_20345	COG0583	DNA-binding transcription factor activity
ITG10_20350	COG2814	Major facilitator Superfamily
ITG10_20365	COG0697	spore germination
ITG10_20385	COG3118	belongs to the thioredoxin family
ITG10_20390	COG4232	protein-disulfide reductase activity
ITG10_20405	COG0668	transmembrane transport
ITG10_20415	COG2197	response regulator
ITG10_20450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ITG10_20455	COG1538	Outer membrane efflux protein
ITG10_20475	COG4989	oxidoreductase activity
ITG10_20485	COG0513	Belongs to the DEAD box helicase family
ITG10_20500	COG2176	DNA-directed DNA polymerase activity
ITG10_20510	COG0513	Belongs to the DEAD box helicase family
ITG10_20535	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ITG10_20540	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ITG10_20545	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ITG10_20550	COG0667	Aldo Keto reductase
ITG10_20565	COG2195	Cleaves the N-terminal amino acid of tripeptides
ITG10_20615	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
ITG10_20620	COG0513	Belongs to the DEAD box helicase family
ITG10_20630	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ITG10_20660	COG0604	alcohol dehydrogenase
ITG10_20690	COG0697	spore germination
ITG10_20705	COG0366	Alpha amylase catalytic
ITG10_20710	COG0583	DNA-binding transcription factor activity
ITG10_20715	COG0534	Mate efflux family protein
ITG10_20720	COG3678	ATP-independent chaperone mediated protein folding
ITG10_20745	COG0516	GMP reductase activity
ITG10_20870	COG0697	spore germination
ITG10_20875	COG0351	phosphomethylpyrimidine kinase
ITG10_20880	COG1116	anion transmembrane transporter activity
ITG10_20885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ITG10_20890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ITG10_20895	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ITG10_20900	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ITG10_20905	COG2801	Transposase and inactivated derivatives
ITG10_20920	COG0352	thiamine-phosphate diphosphorylase activity
ITG10_20930	COG0583	DNA-binding transcription factor activity
ITG10_20955	COG0402	S-adenosylhomocysteine deaminase activity
ITG10_20975	COG3706	GGDEF domain
ITG10_20985	COG1566	PFAM secretion protein HlyD family protein
ITG10_20995	COG0628	permease
ITG10_21030	COG4607	ABC-type enterochelin transport system periplasmic component
ITG10_21035	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ITG10_21040	COG4605	iron ion homeostasis
ITG10_21045	COG4604	ABC transporter, ATP-binding protein
ITG10_21050	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ITG10_21060	COG0573	inorganic phosphate transmembrane transporter activity
ITG10_21065	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ITG10_21070	COG3437	response regulator, receiver
ITG10_21075	COG0784	Response regulator, receiver
ITG10_21075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ITG10_21075	COG2198	Histidine kinase
ITG10_21075	COG2205	protein histidine kinase activity
ITG10_21080	COG0583	DNA-binding transcription factor activity
ITG10_21085	COG2814	Major facilitator Superfamily
ITG10_21105	COG1522	sequence-specific DNA binding
ITG10_21110	COG0840	transmembrane signaling receptor activity
ITG10_21125	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ITG10_21145	COG2897	thiosulfate sulfurtransferase activity
ITG10_21175	COG0302	gtp cyclohydrolase
ITG10_21185	COG4681	YaeQ
ITG10_21190	COG1278	Cold shock
ITG10_21195	COG2133	pyrroloquinoline quinone binding
ITG10_21205	COG1120	ATPase activity
ITG10_21235	COG1024	Enoyl-CoA hydratase
ITG10_21255	COG2985	domain, Protein
ITG10_21265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ITG10_21270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ITG10_21285	COG3710	Transcriptional regulator
ITG10_21295	COG1902	pentaerythritol trinitrate reductase activity
ITG10_21295	COG0446	pyridine nucleotide-disulphide oxidoreductase
ITG10_21320	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ITG10_21350	COG2824	Alkylphosphonate utilization operon protein PhnA
ITG10_21390	COG1280	lysine exporter protein (LysE YggA)
ITG10_21415	COG0765	amino acid transport
ITG10_21425	COG0765	amino acid transport
ITG10_21430	COG1126	abc transporter atp-binding protein
ITG10_21435	COG1979	alcohol dehydrogenase
ITG10_21440	COG2207	Transcriptional regulator
ITG10_21475	COG3059	membrane
ITG10_21495	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ITG10_21505	COG3706	GGDEF domain
ITG10_21520	COG1686	Belongs to the peptidase S11 family
ITG10_21530	COG0583	DNA-binding transcription factor activity
ITG10_21540	COG0564	pseudouridine synthase activity
ITG10_21550	COG2130	NADP-dependent
ITG10_21555	COG1309	transcriptional regulator
ITG10_21560	COG0545	Peptidyl-prolyl cis-trans isomerase
ITG10_21580	COG3604	Transcriptional regulator
ITG10_21585	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ITG10_21585	COG1017	nitric oxide dioxygenase activity
ITG10_21590	COG1609	Transcriptional regulator
ITG10_21600	COG1175	transmembrane transport
ITG10_21605	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ITG10_21615	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ITG10_21625	COG0038	chloride channel
ITG10_21630	COG0523	cobalamin synthesis protein
ITG10_21635	COG0513	Belongs to the DEAD box helicase family
ITG10_21665	COG0745	RESPONSE REGULATOR receiver
ITG10_21720	COG0183	Belongs to the thiolase family
ITG10_21730	COG3243	poly(R)-hydroxyalkanoic acid synthase
ITG10_21755	COG0243	molybdopterin cofactor binding
ITG10_21765	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ITG10_21765	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
ITG10_21770	COG3850	Histidine kinase
ITG10_21775	COG2197	response regulator
ITG10_21780	COG3069	C4-dicarboxylate transmembrane transporter activity
ITG10_21800	COG2067	long-chain fatty acid transport protein
ITG10_21805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ITG10_21810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ITG10_21835	COG2188	Transcriptional regulator
ITG10_21840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ITG10_21840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ITG10_21840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ITG10_21845	COG0383	alpha-mannosidase activity
ITG10_21850	COG1929	Belongs to the glycerate kinase type-1 family
ITG10_21880	COG3706	GGDEF domain
ITG10_21975	COG3706	GGDEF domain
ITG10_21985	COG2197	response regulator
ITG10_22005	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ITG10_22010	COG0494	nUDIX hydrolase
ITG10_22015	COG0714	Associated with various cellular activities
ITG10_22020	COG2425	protein containing a von Willebrand factor type A (vWA) domain
ITG10_22045	COG0840	transmembrane signaling receptor activity
ITG10_22085	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ITG10_22095	COG2116	formate transmembrane transporter activity
ITG10_22100	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ITG10_22100	COG1648	precorrin-2 dehydrogenase activity
ITG10_22115	COG0745	RESPONSE REGULATOR receiver
ITG10_22120	COG2205	protein histidine kinase activity
ITG10_22125	COG1301	dicarboxylic acid transport
ITG10_22130	COG4774	siderophore transport
ITG10_22140	COG0811	peptide transport
ITG10_22145	COG0811	peptide transport
ITG10_22150	COG0848	biopolymer transport protein
ITG10_22195	COG0803	Belongs to the bacterial solute-binding protein 9 family
ITG10_22200	COG1121	(ABC) transporter
ITG10_22205	COG1321	iron dependent repressor
ITG10_22205	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ITG10_22230	COG0534	Mate efflux family protein
ITG10_22260	COG0318	PFAM AMP-dependent synthetase and ligase
ITG10_22270	COG3118	belongs to the thioredoxin family
ITG10_22275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ITG10_22295	COG2391	methyltransferase activity
ITG10_22305	COG1328	CTP reductase activity
ITG10_22310	COG0602	queuosine metabolic process
ITG10_22330	COG4067	protein conserved in archaea
ITG10_22330	COG0189	ligase activity
ITG10_22335	COG0488	(ABC) transporter
ITG10_22340	COG2963	transposase activity
ITG10_22345	COG2801	Transposase and inactivated derivatives
ITG10_22350	COG2801	Transposase and inactivated derivatives
ITG10_22380	COG0725	ABC transporter, periplasmic molybdate-binding protein
ITG10_22385	COG4149	molybdate abc transporter
ITG10_22390	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ITG10_22400	COG2203	Gaf domain
ITG10_22400	COG3706	GGDEF domain
ITG10_22400	COG4251	negative regulation of phosphorylation
ITG10_22400	COG5001	Diguanylate cyclase
ITG10_22410	COG3706	GGDEF domain
ITG10_22425	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ITG10_22430	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ITG10_22455	COG3140	Belongs to the UPF0181 family
ITG10_22460	COG3706	GGDEF domain
ITG10_22470	COG0023	Translation Initiation Factor
ITG10_22485	COG1181	Belongs to the D-alanine--D-alanine ligase family
ITG10_22490	COG3266	domain, Protein
ITG10_22495	COG1042	CoA-binding domain protein
ITG10_22495	COG0045	succinate-CoA ligase (ADP-forming) activity
ITG10_22495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ITG10_22500	COG0583	DNA-binding transcription factor activity
ITG10_22505	COG4771	TonB-dependent receptor
ITG10_22505	COG1629	transport
ITG10_22535	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ITG10_22540	COG1984	allophanate hydrolase subunit 2
ITG10_22550	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ITG10_22555	COG4181	ATPase activity
ITG10_22565	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ITG10_22570	COG1716	ATPase activity
ITG10_22570	COG5001	Diguanylate cyclase
ITG10_22580	COG0768	penicillin binding
ITG10_22610	COG4533	DNA binding
ITG10_22620	COG2050	protein possibly involved in aromatic compounds catabolism
ITG10_22625	COG0501	Belongs to the peptidase M48B family
ITG10_22635	COG2067	long-chain fatty acid transport protein
ITG10_22640	COG2267	carboxylic ester hydrolase activity
ITG10_22655	COG0583	DNA-binding transcription factor activity
ITG10_22670	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ITG10_22700	COG1566	PFAM secretion protein HlyD family protein
ITG10_22720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ITG10_22730	COG0729	surface antigen
ITG10_22735	COG0513	Belongs to the DEAD box helicase family
ITG10_22750	COG0861	Integral membrane protein TerC family
ITG10_22755	COG0737	Belongs to the 5'-nucleotidase family
ITG10_22760	COG3593	DNA synthesis involved in DNA repair
ITG10_22770	COG0583	DNA-binding transcription factor activity
ITG10_22775	COG2116	formate transmembrane transporter activity
ITG10_22780	COG2353	YceI-like domain
ITG10_22785	COG3038	cytochrome b561
ITG10_22800	COG2200	EAL domain
ITG10_22830	COG0513	Belongs to the DEAD box helicase family
ITG10_22835	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
ITG10_22840	COG0814	amino acid
ITG10_22850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ITG10_22855	COG0784	Response regulator, receiver
ITG10_22855	COG3437	response regulator, receiver
ITG10_22870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ITG10_22875	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ITG10_22885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ITG10_22930	COG0509	glycine decarboxylation via glycine cleavage system
ITG10_22950	COG0534	Mate efflux family protein
ITG10_22970	COG1280	lysine exporter protein (LysE YggA)
ITG10_22990	COG3227	Zinc metalloprotease (Elastase)
ITG10_23010	COG2807	transmembrane transport
ITG10_23020	COG1881	PFAM PEBP family protein
ITG10_23070	COG0840	transmembrane signaling receptor activity
ITG10_23120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ITG10_23125	COG2205	protein histidine kinase activity
ITG10_23125	COG0784	Response regulator, receiver
ITG10_23130	COG1538	Outer membrane efflux protein
ITG10_23150	COG0784	Response regulator, receiver
ITG10_23150	COG2205	protein histidine kinase activity
ITG10_23150	COG5002	protein histidine kinase activity
ITG10_23185	COG0840	transmembrane signaling receptor activity
ITG10_23190	COG0405	Gamma-glutamyltransferase
ITG10_23200	COG0641	radical SAM
ITG10_23215	COG1597	lipid kinase activity
ITG10_23220	COG0583	DNA-binding transcription factor activity
ITG10_23250	COG0714	Associated with various cellular activities
ITG10_23265	COG3119	arylsulfatase activity
ITG10_23285	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
ITG10_23305	COG2197	response regulator
ITG10_23310	COG0456	acetyltransferase
ITG10_23320	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ITG10_23355	COG0384	phenazine biosynthesis protein PhzF
ITG10_23365	COG5001	Diguanylate cyclase
ITG10_23365	COG3300	MHYT domain
ITG10_23385	COG3278	Belongs to the heme-copper respiratory oxidase family
ITG10_23425	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ITG10_23435	COG1012	belongs to the aldehyde dehydrogenase family
ITG10_23445	COG0583	DNA-binding transcription factor activity
ITG10_23455	COG0356	it plays a direct role in the translocation of protons across the membrane
ITG10_23470	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ITG10_23480	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ITG10_23490	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ITG10_23500	COG0583	DNA-binding transcription factor activity
ITG10_23520	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ITG10_23530	COG1609	Transcriptional regulator
ITG10_23535	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ITG10_23545	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ITG10_23545	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ITG10_23560	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ITG10_23575	COG0745	RESPONSE REGULATOR receiver
ITG10_23590	COG4608	Belongs to the ABC transporter superfamily
ITG10_23595	COG0444	Belongs to the ABC transporter superfamily
ITG10_23605	COG4239	(ABC) transporter, permease
ITG10_23610	COG4174	ABC transporter (Permease)
ITG10_23615	COG4172	Belongs to the ABC transporter superfamily
ITG10_23620	COG4239	(ABC) transporter, permease
ITG10_23625	COG4174	ABC transporter (Permease)
ITG10_23630	COG4166	transmembrane transport
ITG10_23655	COG1869	D-ribose catabolic process
ITG10_23660	COG1129	ABC transporter
ITG10_23665	COG1172	Belongs to the binding-protein-dependent transport system permease family
ITG10_23670	COG1879	ABC-type sugar transport system periplasmic component
ITG10_23675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ITG10_23680	COG1609	Transcriptional regulator
ITG10_23700	COG0784	Response regulator, receiver
ITG10_23700	COG2205	protein histidine kinase activity
ITG10_23745	COG2026	Addiction module toxin, RelE StbE family
ITG10_23755	COG0243	molybdopterin cofactor binding
ITG10_23760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ITG10_23770	COG2223	nitrite transmembrane transporter activity
ITG10_23775	COG0515	serine threonine protein kinase
ITG10_23775	COG2815	serine threonine protein kinase
ITG10_23780	COG1609	Transcriptional regulator
ITG10_23785	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ITG10_23785	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ITG10_23790	COG1105	Belongs to the carbohydrate kinase PfkB family
ITG10_23795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ITG10_23795	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ITG10_23795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ITG10_23805	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ITG10_23830	COG0745	RESPONSE REGULATOR receiver
ITG10_23835	COG2205	protein histidine kinase activity
ITG10_23850	COG1252	NADH dehydrogenase
ITG10_23855	COG0625	glutathione transferase activity
ITG10_23905	COG2205	protein histidine kinase activity
ITG10_23905	COG2198	Histidine kinase
ITG10_23905	COG0784	Response regulator, receiver
ITG10_23910	COG1879	ABC-type sugar transport system periplasmic component
ITG10_23915	COG1803	Methylglyoxal synthase
ITG10_23920	COG2801	Transposase and inactivated derivatives
ITG10_23925	COG2801	Transposase and inactivated derivatives
ITG10_23930	COG2963	transposase activity
ITG10_23940	COG0210	DNA helicase
ITG10_23945	COG1289	transmembrane transporter activity
ITG10_23965	COG0583	DNA-binding transcription factor activity
ITG10_23970	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ITG10_23975	COG1328	CTP reductase activity
ITG10_24005	COG1011	Hydrolase
ITG10_24015	COG1454	alcohol dehydrogenase
ITG10_24035	COG2249	NAD(P)H dehydrogenase (quinone) activity
ITG10_24065	COG1063	alcohol dehydrogenase
ITG10_24070	COG0156	8-amino-7-oxononanoate synthase activity
ITG10_24075	COG2200	EAL domain
ITG10_24085	COG2211	Major facilitator Superfamily
ITG10_24090	COG0577	efflux transmembrane transporter activity
ITG10_24090	COG1136	(ABC) transporter
ITG10_24095	COG0577	efflux transmembrane transporter activity
ITG10_24095	COG1136	(ABC) transporter
ITG10_24110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ITG10_24120	COG0346	lactoylglutathione lyase activity
ITG10_24140	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ITG10_24145	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ITG10_24160	COG0393	Putative heavy-metal-binding
ITG10_24165	COG0739	heme binding
ITG10_24195	COG1132	(ABC) transporter
ITG10_24200	COG1132	(ABC) transporter
ITG10_24215	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ITG10_24235	COG1760	l-serine dehydratase
ITG10_24240	COG3104	oligopeptide transport
ITG10_24250	COG2375	cellular response to nickel ion
ITG10_24270	COG3842	ATPase activity
ITG10_24280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ITG10_24285	COG1840	ABC-type Fe3 transport system, periplasmic component
ITG10_24295	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ITG10_24310	COG1765	OsmC-like protein
ITG10_24315	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ITG10_24315	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ITG10_24330	COG2801	Transposase and inactivated derivatives
ITG10_24335	COG2963	transposase activity
ITG10_24340	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ITG10_24345	COG0569	domain protein
ITG10_24350	COG0668	transmembrane transport
ITG10_24355	COG0662	Cupin 2, conserved barrel domain protein
ITG10_24355	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ITG10_24370	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ITG10_24380	COG3530	Putative quorum-sensing-regulated virulence factor
ITG10_24400	COG0109	protoheme IX farnesyltransferase activity
ITG10_24405	COG1612	heme a metabolic process
ITG10_24425	COG1845	cytochrome c oxidase, subunit III
ITG10_24435	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ITG10_24440	COG1565	acr, cog1565
ITG10_24440	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ITG10_24445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ITG10_24455	COG1280	lysine exporter protein (LysE YggA)
ITG10_24460	COG0179	Fumarylacetoacetate (FAA) hydrolase
ITG10_24470	COG0443	Heat shock 70 kDa protein
ITG10_24500	COG2827	Endonuclease containing a URI domain
ITG10_24505	COG3132	Protein of unknown function, DUF480
ITG10_24515	COG2926	Belongs to the UPF0265 family
ITG10_24540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ITG10_24545	COG1151	hydroxylamine reductase activity
ITG10_24560	COG1280	lysine exporter protein (LysE YggA)
ITG10_24575	COG0531	amino acid
ITG10_24590	COG4413	Urea transporter
ITG10_24610	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ITG10_24615	COG0402	S-adenosylhomocysteine deaminase activity
ITG10_24620	COG1278	Cold shock
ITG10_24625	COG3706	GGDEF domain
ITG10_24640	COG0513	Belongs to the DEAD box helicase family
ITG10_24655	COG4106	trans-aconitate 2-methyltransferase activity
ITG10_24660	COG2205	protein histidine kinase activity
ITG10_24665	COG0745	RESPONSE REGULATOR receiver
ITG10_24670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ITG10_24690	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ITG10_24705	COG3037	sugar-specific permease SgaT UlaA
ITG10_24710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ITG10_24715	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ITG10_24720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ITG10_24725	COG2205	protein histidine kinase activity
ITG10_24730	COG0745	RESPONSE REGULATOR receiver
ITG10_24740	COG5001	Diguanylate cyclase
ITG10_24755	COG2200	EAL domain
ITG10_24765	COG2186	Transcriptional regulator
ITG10_24770	COG1131	(ABC) transporter
ITG10_24795	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ITG10_24795	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ITG10_24805	COG0564	pseudouridine synthase activity
ITG10_24815	COG2814	Major facilitator Superfamily
ITG10_24835	COG4977	sequence-specific DNA binding
ITG10_24870	COG4533	DNA binding
ITG10_24875	COG0189	ligase activity
ITG10_24880	COG0189	ligase activity
ITG10_24880	COG4067	protein conserved in archaea
ITG10_24900	COG1175	transmembrane transport
ITG10_24905	COG0395	ABC-type sugar transport system, permease component
ITG10_24910	COG3842	ATPase activity
ITG10_24915	COG0584	glycerophosphoryl diester phosphodiesterase
ITG10_24935	COG0673	inositol 2-dehydrogenase activity
ITG10_24945	COG2999	glutathione oxidoreductase activity
ITG10_24950	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ITG10_24960	COG2801	Transposase and inactivated derivatives
ITG10_24995	COG0534	Mate efflux family protein
ITG10_25000	COG0110	maltose O-acetyltransferase activity
ITG10_25005	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ITG10_25015	COG3454	Phosphonate metabolism
ITG10_25020	COG4778	phosphonate C-P lyase system protein PhnL
ITG10_25025	COG4107	phosphonate C-P lyase system protein PhnK
ITG10_25030	COG3627	carbon phosphorus lyase activity
ITG10_25035	COG3626	phosphonate metabolism
ITG10_25040	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
ITG10_25045	COG3624	Phosphonate C-P lyase system protein PhnG
ITG10_25050	COG2188	Transcriptional regulator
ITG10_25055	COG3639	organic phosphonate transmembrane transporter activity
ITG10_25060	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ITG10_25090	COG0446	pyridine nucleotide-disulphide oxidoreductase
ITG10_25290	COG1901	pseudouridine methyltransferase
ITG10_25310	COG1595	DNA-templated transcription, initiation
ITG10_25315	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ITG10_25345	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ITG10_25360	COG1028	Short-chain dehydrogenase reductase Sdr
ITG10_25365	COG1733	regulation of RNA biosynthetic process
ITG10_25370	COG0583	DNA-binding transcription factor activity
ITG10_25375	COG4221	oxidoreductase activity
ITG10_25385	COG3047	cAMP biosynthetic process
ITG10_25390	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ITG10_25395	COG1288	antiporter activity
ITG10_25440	COG3639	organic phosphonate transmembrane transporter activity
ITG10_25445	COG3639	organic phosphonate transmembrane transporter activity
ITG10_25450	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ITG10_25475	COG4948	Mandelate Racemase Muconate Lactonizing
ITG10_25485	COG0583	DNA-binding transcription factor activity
ITG10_25520	COG0583	DNA-binding transcription factor activity
ITG10_25540	COG2801	Transposase and inactivated derivatives
ITG10_25545	COG2801	Transposase and inactivated derivatives
ITG10_25550	COG2801	Transposase and inactivated derivatives
ITG10_25585	COG1757	Na H antiporter
ITG10_25590	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ITG10_25615	COG2814	Major facilitator Superfamily
ITG10_25620	COG0814	amino acid
ITG10_25625	COG0840	transmembrane signaling receptor activity
ITG10_25635	COG0702	epimerase
ITG10_25645	COG3226	Transcriptional regulator
ITG10_25655	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ITG10_25660	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ITG10_25670	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ITG10_25675	COG2207	Transcriptional regulator
ITG10_25680	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ITG10_25680	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ITG10_25680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ITG10_25695	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ITG10_25705	COG0765	amino acid transport
ITG10_25710	COG3842	ATPase activity
ITG10_25715	COG0546	phosphoglycolate phosphatase activity
ITG10_25740	COG0583	DNA-binding transcription factor activity
ITG10_25745	COG4166	transmembrane transport
ITG10_25775	COG3547	Transposase (IS116 IS110 IS902 family)
ITG10_25795	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ITG10_25805	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ITG10_25820	COG1012	belongs to the aldehyde dehydrogenase family
ITG10_25825	COG3284	Transcriptional regulator
ITG10_25830	COG0415	Belongs to the DNA photolyase family
ITG10_25840	COG0625	glutathione transferase activity
ITG10_25845	COG3655	Transcriptional regulator
ITG10_25860	COG1621	beta-fructofuranosidase activity
ITG10_25865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ITG10_25870	COG1263	PTS System
ITG10_25870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ITG10_25910	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ITG10_25915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ITG10_25920	COG1418	mRNA catabolic process
ITG10_25935	COG2186	Transcriptional regulator