locus-tag	class	description
N5E84_00005	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
N5E84_00010	COG3028	Belongs to the UPF0307 family
N5E84_00020	COG2239	Acts as a magnesium transporter
N5E84_00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N5E84_00075	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
N5E84_00090	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
N5E84_00090	COG0517	IMP dehydrogenase activity
N5E84_00100	COG1127	ABC transporter
N5E84_00105	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
N5E84_00110	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
N5E84_00150	COG0251	oxidation-reduction process
N5E84_00155	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
N5E84_00170	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
N5E84_00180	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N5E84_00200	COG0525	valine-tRNA ligase activity
N5E84_00205	COG2927	DNA polymerase III (CHI subunit)
N5E84_00240	COG3328	transposase activity
N5E84_00290	COG0066	3-isopropylmalate dehydratase activity
N5E84_00300	COG0473	3-isopropylmalate dehydrogenase activity
N5E84_00320	COG3335	DDE superfamily endonuclease
N5E84_00345	COG0737	Belongs to the 5'-nucleotidase family
N5E84_00350	COG1648	precorrin-2 dehydrogenase activity
N5E84_00350	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N5E84_00355	COG0175	sulfate reduction
N5E84_00360	COG2895	sulfate adenylyltransferase (ATP) activity
N5E84_00365	COG0529	Catalyzes the synthesis of activated sulfate
N5E84_00400	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
N5E84_00405	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N5E84_00465	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
N5E84_00475	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N5E84_00480	COG0163	prenyltransferase activity
N5E84_00490	COG1178	ABC-type Fe3 transport system permease component
N5E84_00495	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
N5E84_00500	COG3028	Belongs to the UPF0307 family
N5E84_00505	COG0312	modulator of DNA gyrase
N5E84_00510	COG2239	Acts as a magnesium transporter
N5E84_00515	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N5E84_00520	COG1660	Displays ATPase and GTPase activities
N5E84_00525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N5E84_00530	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
N5E84_00540	COG1137	ATPase activity
N5E84_00545	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
N5E84_00560	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
N5E84_00560	COG0517	IMP dehydrogenase activity
N5E84_00570	COG1127	ABC transporter
N5E84_00575	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
N5E84_00580	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
N5E84_00585	COG2854	intermembrane phospholipid transfer
N5E84_00595	COG5007	Belongs to the BolA IbaG family
N5E84_00600	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N5E84_00605	COG0204	Acyl-transferase
N5E84_00620	COG0251	oxidation-reduction process
N5E84_00675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N5E84_00690	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
N5E84_00700	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
N5E84_00710	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
N5E84_00720	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
N5E84_00750	COG3328	transposase activity
N5E84_00800	COG0066	3-isopropylmalate dehydratase activity
N5E84_00810	COG0473	3-isopropylmalate dehydrogenase activity
N5E84_00830	COG3335	DDE superfamily endonuclease
N5E84_00835	COG0583	DNA-binding transcription factor activity
N5E84_00840	COG1022	Amp-dependent synthetase and ligase
N5E84_00845	COG0028	Belongs to the TPP enzyme family
N5E84_00855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N5E84_00865	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
N5E84_00875	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
N5E84_00880	COG3079	Belongs to the UPF0149 family
N5E84_00885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N5E84_00890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N5E84_00905	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
N5E84_00915	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
N5E84_00920	COG1595	DNA-templated transcription, initiation
N5E84_00935	COG3086	response to oxidative stress
N5E84_00940	COG0481	GTPase activity
N5E84_00950	COG0571	ribonuclease III activity
N5E84_00955	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
N5E84_00960	COG1381	Involved in DNA repair and RecF pathway recombination
N5E84_00965	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
N5E84_00970	COG0736	holo-[acyl-carrier-protein] synthase activity
N5E84_00975	COG4999	Histidine kinase
N5E84_00975	COG2205	protein histidine kinase activity
N5E84_00975	COG3437	response regulator, receiver
N5E84_00975	COG3850	Histidine kinase
N5E84_00980	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N5E84_00985	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N5E84_00990	COG3956	TIGRFAM MazG family protein
N5E84_00995	COG0504	CTP synthase activity
N5E84_01005	COG0617	tRNA 3'-terminal CCA addition
N5E84_01010	COG3267	Type II secretory pathway component ExeA
N5E84_01010	COG3409	Peptidoglycan-binding domain 1 protein
N5E84_01020	COG4991	sh3 domain protein
N5E84_01025	COG0306	phosphate transporter
N5E84_01030	COG1392	Phosphate transport regulator
N5E84_01035	COG3025	triphosphatase activity
N5E84_01045	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
N5E84_01055	COG1538	Outer membrane efflux protein
N5E84_01060	COG0494	nUDIX hydrolase
N5E84_01065	COG3151	Protein conserved in bacteria
N5E84_01075	COG3150	esterase
N5E84_01080	COG0187	DNA topoisomerase II activity
N5E84_01085	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N5E84_01090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N5E84_01095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N5E84_01100	COG3105	Protein conserved in bacteria
N5E84_01105	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
N5E84_01110	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
N5E84_01120	COG0723	plastoquinol--plastocyanin reductase activity
N5E84_01125	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
N5E84_01130	COG2857	Cytochrome c1
N5E84_01135	COG0625	glutathione transferase activity
N5E84_01140	COG2969	positive regulation of protein catabolic process
N5E84_01150	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
N5E84_01155	COG0792	nuclease activity
N5E84_01160	COG3107	peptidoglycan biosynthetic process
N5E84_01165	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
N5E84_01175	COG0275	rRNA processing
N5E84_01180	COG3116	cell division
N5E84_01185	COG0768	penicillin binding
N5E84_01190	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
N5E84_01195	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
N5E84_01205	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
N5E84_01210	COG0772	Belongs to the SEDS family
N5E84_01215	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N5E84_01220	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N5E84_01225	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
N5E84_01230	COG0849	cell division
N5E84_01235	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
N5E84_01240	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
N5E84_01250	COG0653	protein targeting
N5E84_01255	COG0494	nUDIX hydrolase
N5E84_01260	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
N5E84_01265	COG0505	Belongs to the CarA family
N5E84_01270	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
N5E84_01275	COG0730	response to heat
N5E84_01280	COG0583	DNA-binding transcription factor activity
N5E84_01285	COG2860	membrane
N5E84_01290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N5E84_01300	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
N5E84_01310	COG0493	'glutamate synthase
N5E84_01315	COG0070	glutamate synthase
N5E84_01315	COG0067	glutamate synthase
N5E84_01315	COG0069	glutamate synthase activity
N5E84_01325	COG0067	glutamate synthase
N5E84_01325	COG0069	glutamate synthase activity
N5E84_01325	COG0070	glutamate synthase
N5E84_01330	COG1242	4 iron, 4 sulfur cluster binding
N5E84_01335	COG0784	Response regulator, receiver
N5E84_01335	COG2198	Histidine kinase
N5E84_01335	COG5002	protein histidine kinase activity
N5E84_01345	COG0745	RESPONSE REGULATOR receiver
N5E84_01350	COG3335	DDE superfamily endonuclease
N5E84_01355	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N5E84_01375	COG0083	homoserine kinase activity
N5E84_01380	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
N5E84_01385	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
N5E84_01390	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
N5E84_01395	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
N5E84_01410	COG1115	amino acid carrier protein
N5E84_01415	COG3022	response to hydroperoxide
N5E84_01425	COG0084	hydrolase, TatD family'
N5E84_01430	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N5E84_01435	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
N5E84_01440	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
N5E84_01445	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
N5E84_01450	COG0813	purine-nucleoside phosphorylase activity
N5E84_01460	COG0560	Phosphoserine phosphatase
N5E84_01470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
N5E84_01475	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
N5E84_01480	COG4628	conserved protein (DUF2132)
N5E84_01485	COG1022	Amp-dependent synthetase and ligase
N5E84_01490	COG0784	Response regulator, receiver
N5E84_01490	COG3437	response regulator, receiver
N5E84_01505	COG1085	galactose-1-phosphate uridylyltransferase
N5E84_01515	COG2017	converts alpha-aldose to the beta-anomer
N5E84_01520	COG1609	Transcriptional regulator
N5E84_01550	COG2171	N-acyltransferase activity
N5E84_01555	COG3141	response to X-ray
N5E84_01570	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
N5E84_01575	COG1074	ATP-dependent DNA helicase activity
N5E84_01580	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N5E84_01590	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
N5E84_01590	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
N5E84_01600	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
N5E84_01605	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
N5E84_01610	COG2166	iron-sulfur cluster assembly
N5E84_01615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N5E84_01625	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
N5E84_01640	COG1595	DNA-templated transcription, initiation
N5E84_01650	COG2211	Major facilitator Superfamily
N5E84_01670	COG0271	Belongs to the BolA IbaG family
N5E84_01705	COG1477	protein flavinylation
N5E84_01715	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N5E84_01725	COG5001	Diguanylate cyclase
N5E84_01725	COG2203	Gaf domain
N5E84_01725	COG4251	negative regulation of phosphorylation
N5E84_01725	COG3706	GGDEF domain
N5E84_01730	COG0733	neurotransmitter:sodium symporter activity
N5E84_01740	COG0189	ligase activity
N5E84_01745	COG0189	ligase activity
N5E84_01745	COG4067	protein conserved in archaea
N5E84_01750	COG2195	Cleaves the N-terminal amino acid of tripeptides
N5E84_01755	COG2252	PERMEase
N5E84_01760	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
N5E84_01765	COG1073	alpha beta
N5E84_01775	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
N5E84_01780	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
N5E84_01785	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
N5E84_01790	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N5E84_01790	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N5E84_01810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N5E84_01815	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
N5E84_01820	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
N5E84_01830	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
N5E84_01835	COG0024	Methionine aminopeptidase
N5E84_01840	COG0052	Belongs to the universal ribosomal protein uS2 family
N5E84_01845	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
N5E84_01855	COG0233	cytoplasmic translational termination
N5E84_01860	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
N5E84_01865	COG0575	Belongs to the CDS family
N5E84_01870	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
N5E84_01875	COG0750	zinc metalloprotease
N5E84_01885	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
N5E84_01890	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N5E84_01895	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N5E84_01905	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N5E84_01915	COG0587	DNA-directed DNA polymerase activity
N5E84_01920	COG0825	malonyl-CoA metabolic process
N5E84_01925	COG0037	tRNA processing
N5E84_01935	COG0347	Belongs to the P(II) protein family
N5E84_01940	COG3021	interspecies interaction between organisms
N5E84_01950	COG1388	LysM domain
N5E84_01950	COG0741	lytic transglycosylase activity
N5E84_01955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N5E84_01960	COG2226	methyltransferase
N5E84_01965	COG0328	RNA-DNA hybrid ribonuclease activity
N5E84_01985	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
N5E84_01990	COG0121	glutamine amidotransferase
N5E84_01995	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
N5E84_02000	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
N5E84_02005	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
N5E84_02010	COG1187	pseudouridine synthase activity
N5E84_02015	COG3385	transposase activity
N5E84_02040	COG2217	Heavy metal translocating P-type atpase
N5E84_02040	COG2608	mercury ion transmembrane transporter activity
N5E84_02085	COG2747	anti-sigma28 factor FlgM
N5E84_02095	COG0784	Response regulator, receiver
N5E84_02095	COG0835	chemotaxis
N5E84_02105	COG1815	bacterial-type flagellum-dependent cell motility
N5E84_02120	COG1749	Flagellar hook protein flgE
N5E84_02125	COG4787	bacterial-type flagellum-dependent cell motility
N5E84_02135	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
N5E84_02140	COG1706	bacterial-type flagellum-dependent cell motility
N5E84_02145	COG3951	Flagellar rod assembly protein muramidase FlgJ
N5E84_02145	COG1705	Flagellar rod assembly protein muramidase FlgJ
N5E84_02155	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N5E84_02255	COG0193	aminoacyl-tRNA hydrolase activity
N5E84_02260	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N5E84_02270	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
N5E84_02275	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
N5E84_02280	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
N5E84_02285	COG2890	protein-(glutamine-N5) methyltransferase activity
N5E84_02295	COG2912	Transglutaminase-like superfamily
N5E84_02300	COG2877	3-deoxy-8-phosphooctulonate synthase activity
N5E84_02310	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
N5E84_02315	COG2233	PERMEase
N5E84_02335	COG1393	Belongs to the ArsC family
N5E84_02340	COG4783	chaperone-mediated protein folding
N5E84_02400	COG3550	peptidyl-serine autophosphorylation
N5E84_02405	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
N5E84_02405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N5E84_02410	COG2433	Pfam Transposase IS66
N5E84_02430	COG2433	Pfam Transposase IS66
N5E84_02470	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
N5E84_02505	COG2433	Pfam Transposase IS66
N5E84_02530	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
N5E84_02550	COG1393	Belongs to the ArsC family
N5E84_02575	COG2837	iron assimilation
N5E84_02600	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
N5E84_02610	COG1516	flagellar protein fliS
N5E84_02630	COG1677	Flagellar hook-basal body complex protein FliE
N5E84_02640	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N5E84_02690	COG1987	bacterial-type flagellum assembly
N5E84_02695	COG1684	flagellar biosynthetic protein fliR
N5E84_02705	COG2840	Smr protein MutS2
N5E84_02710	COG2890	protein-(glutamine-N5) methyltransferase activity
N5E84_02715	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
N5E84_02720	COG2860	membrane
N5E84_02730	COG3101	peptidyl-lysine hydroxylation
N5E84_02740	COG0431	NADPH-dependent FMN reductase
N5E84_02745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N5E84_02745	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
N5E84_02750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N5E84_02755	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N5E84_02760	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
N5E84_02765	COG0735	belongs to the Fur family
N5E84_02775	COG0583	DNA-binding transcription factor activity
N5E84_02785	COG1346	cytolysis
N5E84_02800	COG0596	Alpha beta hydrolase
N5E84_02805	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
N5E84_02810	COG0033	Phosphoglucomutase
N5E84_02820	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
N5E84_02835	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
N5E84_02850	COG0567	Dehydrogenase, E1 component
N5E84_02855	COG0508	dehydrogenase complex catalyzes the overall conversion of
N5E84_02870	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N5E84_02875	COG1121	(ABC) transporter
N5E84_02880	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
N5E84_02885	COG4977	sequence-specific DNA binding
N5E84_02890	COG1918	ferrous iron import across plasma membrane
N5E84_02915	COG3102	Protein conserved in bacteria
N5E84_02920	COG1025	Belongs to the peptidase M16 family
N5E84_02925	COG2062	phosphohistidine phosphatase, SixA
N5E84_02930	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
N5E84_02955	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
N5E84_02960	COG2198	Histidine kinase
N5E84_02960	COG0643	Histidine kinase
N5E84_02960	COG0784	Response regulator, receiver
N5E84_02965	COG2201	protein-glutamate methylesterase activity
N5E84_02970	COG1192	Involved in chromosome partitioning
N5E84_02980	COG0835	chemotaxis
N5E84_02990	COG4133	protoheme IX ABC transporter activity
N5E84_02995	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N5E84_03000	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N5E84_03010	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
N5E84_03015	COG1138	Cytochrome C-type biogenesis protein
N5E84_03020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N5E84_03035	COG2853	Lipoprotein
N5E84_03055	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
N5E84_03105	COG0732	type I restriction modification DNA specificity domain
N5E84_03110	COG1196	nuclear chromosome segregation
N5E84_03120	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
N5E84_03150	COG3501	Rhs element vgr protein
N5E84_03165	COG3335	DDE superfamily endonuclease
N5E84_03210	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
N5E84_03215	COG0243	molybdopterin cofactor binding
N5E84_03230	COG3082	Protein of unknown function (DUF1414)
N5E84_03245	COG3385	transposase activity
N5E84_03250	COG1757	Na H antiporter
N5E84_03255	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
N5E84_03260	COG2095	MarC family integral membrane protein
N5E84_03265	COG1012	belongs to the aldehyde dehydrogenase family
N5E84_03265	COG1454	alcohol dehydrogenase
N5E84_03275	COG1530	ribonuclease E activity
N5E84_03280	COG0564	pseudouridine synthase activity
N5E84_03285	COG0424	maF-like protein
N5E84_03290	COG1399	metal-binding, possibly nucleic acid-binding protein
N5E84_03305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N5E84_03330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N5E84_03335	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N5E84_03340	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
N5E84_03345	COG0470	DNA polymerase III
N5E84_03350	COG0084	hydrolase, TatD family'
N5E84_03355	COG1263	PTS System
N5E84_03355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N5E84_03365	COG0733	neurotransmitter:sodium symporter activity
N5E84_03380	COG4667	esterase of the alpha-beta hydrolase superfamily
N5E84_03390	COG1940	carbohydrate kinase activity
N5E84_03395	COG0784	Response regulator, receiver
N5E84_03395	COG0835	chemotaxis
N5E84_03400	COG1028	Short-chain dehydrogenase reductase Sdr
N5E84_03405	COG0616	signal peptide processing
N5E84_03420	COG0232	Belongs to the dGTPase family. Type 2 subfamily
N5E84_03425	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
N5E84_03430	COG0436	Aminotransferase
N5E84_03435	COG1169	isochorismate synthase
N5E84_03440	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
N5E84_03450	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
N5E84_03460	COG0318	PFAM AMP-dependent synthetase and ligase
N5E84_03495	COG1522	sequence-specific DNA binding
N5E84_03500	COG1946	Acyl-CoA thioesterase
N5E84_03505	COG3126	Type III secretion system lipoprotein chaperone (YscW)
N5E84_03520	COG3706	GGDEF domain
N5E84_03545	COG3335	DDE superfamily endonuclease
N5E84_03565	COG1061	Type III restriction enzyme res subunit
N5E84_03580	COG3335	DDE superfamily endonuclease
N5E84_03590	COG1022	Amp-dependent synthetase and ligase
N5E84_03600	COG0300	oxidoreductase activity
N5E84_03610	COG0745	RESPONSE REGULATOR receiver
N5E84_03615	COG0642	Histidine kinase
N5E84_03625	COG2433	Pfam Transposase IS66
N5E84_03655	COG2985	domain, Protein
N5E84_03665	COG5002	protein histidine kinase activity
N5E84_03665	COG3850	Histidine kinase
N5E84_03680	COG1609	Transcriptional regulator
N5E84_03685	COG0129	dihydroxy-acid dehydratase activity
N5E84_03690	COG3265	gluconokinase activity
N5E84_03695	COG2610	gluconate transmembrane transporter activity
N5E84_03700	COG0800	Aldolase
N5E84_03750	COG1028	Short-chain dehydrogenase reductase Sdr
N5E84_03760	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N5E84_03790	COG1216	Glycosyl transferase, family 2
N5E84_03810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N5E84_03815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N5E84_03840	COG0784	Response regulator, receiver
N5E84_03840	COG5002	protein histidine kinase activity
N5E84_03855	COG0601	transmembrane transport
N5E84_03860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N5E84_03865	COG0444	Belongs to the ABC transporter superfamily
N5E84_03875	COG0435	Glutathione S-transferase
N5E84_03880	COG0280	phosphate acetyltransferase
N5E84_03880	COG0857	belongs to the CobB CobQ family
N5E84_03885	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
N5E84_03890	COG3092	negative regulation of chromosome organization
N5E84_03900	COG4120	Belongs to the binding-protein-dependent transport system permease family
N5E84_03910	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N5E84_03920	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
N5E84_03925	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
N5E84_03935	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N5E84_03940	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
N5E84_03950	COG2226	methyltransferase
N5E84_03955	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
N5E84_03965	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
N5E84_03970	COG2186	Transcriptional regulator
N5E84_03985	COG0537	adenosine 5'-monophosphoramidase activity
N5E84_04010	COG3150	esterase
N5E84_04015	COG1252	NADH dehydrogenase
N5E84_04030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
N5E84_04040	COG4591	ABC-type transport system involved in lipoprotein release permease component
N5E84_04045	COG1136	(ABC) transporter
N5E84_04050	COG4591	ABC-type transport system involved in lipoprotein release permease component
N5E84_04060	COG2333	competence protein COMEC
N5E84_04060	COG0658	competence protein
N5E84_04065	COG1132	(ABC) transporter
N5E84_04080	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
N5E84_04085	COG2719	SpoVR family
N5E84_04090	COG2718	Belongs to the UPF0229 family
N5E84_04095	COG2766	serine protein kinase
N5E84_04100	COG3013	Belongs to the UPF0304 family
N5E84_04110	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
N5E84_04125	COG1882	Formate acetyltransferase
N5E84_04150	COG4160	amino acid transport
N5E84_04155	COG0708	Exodeoxyribonuclease III
N5E84_04175	COG2433	Pfam Transposase IS66
N5E84_04200	COG0840	transmembrane signaling receptor activity
N5E84_04210	COG3923	Primosomal replication protein n
N5E84_04220	COG1199	ATP-dependent helicase activity
N5E84_04235	COG3012	SEC-C Motif Domain Protein
N5E84_04240	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
N5E84_04245	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N5E84_04250	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
N5E84_04255	COG0215	cysteine-tRNA ligase activity
N5E84_04260	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
N5E84_04265	COG0632	four-way junction helicase activity
N5E84_04270	COG2255	four-way junction helicase activity
N5E84_04275	COG1271	oxidase subunit
N5E84_04280	COG1294	oxidase, subunit
N5E84_04285	COG4890	Cyd operon protein YbgT
N5E84_04290	COG3790	cyd operon protein YbgE
N5E84_04295	COG0824	Thioesterase
N5E84_04300	COG0811	peptide transport
N5E84_04315	COG0823	Involved in the tonB-independent uptake of proteins
N5E84_04320	COG2885	chlorophyll binding
N5E84_04325	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
N5E84_04330	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
N5E84_04340	COG5002	protein histidine kinase activity
N5E84_04340	COG0784	Response regulator, receiver
N5E84_04385	COG1960	acyl-CoA dehydrogenase activity
N5E84_04390	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
N5E84_04420	COG0277	FAD linked oxidase domain protein
N5E84_04420	COG0247	lactate metabolic process
N5E84_04435	COG2986	histidine ammonia-lyase
N5E84_04445	COG0010	Belongs to the arginase family
N5E84_04450	COG1228	amidohydrolase
N5E84_04455	COG2188	Transcriptional regulator
N5E84_04460	COG3097	Belongs to the UPF0267 family
N5E84_04465	COG3099	Belongs to the UPF0263 family
N5E84_04470	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
N5E84_04480	COG0417	DNA replication proofreading
N5E84_04485	COG2197	response regulator
N5E84_04490	COG0322	excinuclease ABC activity
N5E84_04530	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
N5E84_04535	COG0072	phenylalanine-tRNA ligase activity
N5E84_04535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N5E84_04540	COG0776	regulation of translation
N5E84_04570	COG5001	Diguanylate cyclase
N5E84_04580	COG1346	cytolysis
N5E84_04585	COG1380	Effector of murein hydrolase LrgA
N5E84_04590	COG2925	Exonuclease
N5E84_04595	COG1823	symporter activity
N5E84_04600	COG0702	epimerase
N5E84_04630	COG2994	toxin metabolic process
N5E84_04635	COG3064	Membrane
N5E84_04635	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
N5E84_04635	COG1073	alpha beta
N5E84_04640	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
N5E84_04645	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
N5E84_04660	COG2988	succinylglutamate desuccinylase activity
N5E84_04665	COG4139	cobalamin transport
N5E84_04670	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
N5E84_04690	COG0583	DNA-binding transcription factor activity
N5E84_04700	COG1451	nucleotide metabolic process
N5E84_04715	COG3063	Type IV pilus biogenesis stability protein PilW
N5E84_04740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N5E84_04755	COG3290	protein histidine kinase activity
N5E84_04760	COG4565	transcriptional regulatory protein
N5E84_04770	COG0784	Response regulator, receiver
N5E84_04770	COG0835	chemotaxis
N5E84_04815	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
N5E84_04895	COG1181	Belongs to the D-alanine--D-alanine ligase family
N5E84_04915	COG1716	ATPase activity
N5E84_04940	COG4991	sh3 domain protein
N5E84_04940	COG3064	Membrane
N5E84_04940	COG0515	serine threonine protein kinase
N5E84_05000	COG3335	DDE superfamily endonuclease
N5E84_05005	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N5E84_05010	COG2200	EAL domain
N5E84_05015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N5E84_05020	COG1263	PTS System
N5E84_05020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N5E84_05030	COG1621	beta-fructofuranosidase activity
N5E84_05035	COG0840	transmembrane signaling receptor activity
N5E84_05045	COG1054	Belongs to the UPF0176 family
N5E84_05050	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
N5E84_05055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N5E84_05065	COG0848	biopolymer transport protein
N5E84_05070	COG0811	peptide transport
N5E84_05075	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
N5E84_05080	COG3721	Heme iron utilization protein
N5E84_05085	COG0748	coenzyme F420 binding
N5E84_05095	COG1940	carbohydrate kinase activity
N5E84_05125	COG2989	Protein conserved in bacteria
N5E84_05130	COG3108	Peptidase M15
N5E84_05135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N5E84_05150	COG1846	Transcriptional regulator
N5E84_05155	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N5E84_05170	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
N5E84_05175	COG1448	Aminotransferase
N5E84_05180	COG3437	response regulator, receiver
N5E84_05180	COG2770	Histidine kinase
N5E84_05185	COG0840	transmembrane signaling receptor activity
N5E84_05190	COG0745	RESPONSE REGULATOR receiver
N5E84_05200	COG2198	Histidine kinase
N5E84_05200	COG0643	Histidine kinase
N5E84_05210	COG0835	chemotaxis
N5E84_05215	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
N5E84_05220	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
N5E84_05225	COG2201	protein-glutamate methylesterase activity
N5E84_05235	COG0017	Asparaginyl-tRNA synthetase
N5E84_05240	COG0840	transmembrane signaling receptor activity
N5E84_05245	COG0720	synthase
N5E84_05250	COG2356	endonuclease I
N5E84_05260	COG1760	l-serine dehydratase
N5E84_05265	COG0814	amino acid
N5E84_05275	COG0494	nUDIX hydrolase
N5E84_05280	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N5E84_05295	COG3106	COG3106 Predicted ATPase
N5E84_05300	COG3768	UPF0283 membrane protein
N5E84_05310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N5E84_05330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N5E84_05355	COG4191	Histidine kinase
N5E84_05355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N5E84_05370	COG1278	Cold shock
N5E84_05375	COG3005	denitrification pathway
N5E84_05380	COG0243	molybdopterin cofactor binding
N5E84_05385	COG0513	Belongs to the DEAD box helicase family
N5E84_05390	COG2723	6-phospho-beta-galactosidase activity
N5E84_05395	COG1609	Transcriptional regulator
N5E84_05425	COG0443	Heat shock 70 kDa protein
N5E84_05440	COG3706	GGDEF domain
N5E84_05460	COG1643	Atp-dependent helicase
N5E84_05475	COG0477	Major facilitator Superfamily
N5E84_05480	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
N5E84_05485	COG1280	lysine exporter protein (LysE YggA)
N5E84_05490	COG1115	amino acid carrier protein
N5E84_05510	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
N5E84_05520	COG0625	glutathione transferase activity
N5E84_05550	COG0811	peptide transport
N5E84_05555	COG0811	peptide transport
N5E84_05560	COG0848	biopolymer transport protein
N5E84_05575	COG4667	esterase of the alpha-beta hydrolase superfamily
N5E84_05580	COG1793	dna ligase
N5E84_05595	COG3001	Fructosamine kinase
N5E84_05605	COG0791	NLP P60 protein
N5E84_05610	COG0840	transmembrane signaling receptor activity
N5E84_05620	COG3148	PFAM DTW domain containing protein
N5E84_05625	COG1940	carbohydrate kinase activity
N5E84_05640	COG0746	molybdenum cofactor guanylyltransferase activity
N5E84_05645	COG3842	ATPase activity
N5E84_05655	COG1840	ABC-type Fe3 transport system, periplasmic component
N5E84_05660	COG2271	Major facilitator Superfamily
N5E84_05675	COG0488	(ABC) transporter
N5E84_05680	COG0004	ammonium transporteR
N5E84_05685	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
N5E84_05695	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
N5E84_05700	COG1177	transmembrane transport
N5E84_05705	COG1176	ABC-type spermidine putrescine transport system, permease component I
N5E84_05710	COG3842	ATPase activity
N5E84_05745	COG2433	Pfam Transposase IS66
N5E84_05805	COG2433	Pfam Transposase IS66
N5E84_05830	COG3278	Belongs to the heme-copper respiratory oxidase family
N5E84_05845	COG2010	Cytochrome c
N5E84_05855	COG2217	Heavy metal translocating P-type atpase
N5E84_05870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N5E84_05875	COG0589	response to stress
N5E84_05880	COG2433	Pfam Transposase IS66
N5E84_05910	COG2433	Pfam Transposase IS66
N5E84_05925	COG3120	sequence-specific DNA binding
N5E84_05930	COG1067	ATP-dependent peptidase activity
N5E84_05935	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N5E84_05950	COG0488	(ABC) transporter
N5E84_05960	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
N5E84_05960	COG0116	Belongs to the methyltransferase superfamily
N5E84_05970	COG0167	dihydroorotate dehydrogenase activity
N5E84_05975	COG2902	Dehydrogenase
N5E84_05985	COG0308	aminopeptidase N
N5E84_06000	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
N5E84_06005	COG1956	GAF domain-containing protein
N5E84_06010	COG1132	(ABC) transporter
N5E84_06015	COG2995	paraquat-inducible protein a
N5E84_06020	COG3008	intermembrane lipid transfer
N5E84_06030	COG2996	Protein conserved in bacteria
N5E84_06045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N5E84_06045	COG0574	Belongs to the PEP-utilizing enzyme family
N5E84_06050	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
N5E84_06055	COG1666	GTP binding
N5E84_06060	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N5E84_06060	COG1648	precorrin-2 dehydrogenase activity
N5E84_06065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N5E84_06070	COG4597	amino acid ABC transporter
N5E84_06075	COG0765	amino acid transport
N5E84_06080	COG1126	abc transporter atp-binding protein
N5E84_06085	COG0670	Belongs to the BI1 family
N5E84_06090	COG2920	part of a sulfur-relay system
N5E84_06095	COG3328	transposase activity
N5E84_06100	COG1254	Belongs to the acylphosphatase family
N5E84_06105	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
N5E84_06135	COG0602	queuosine metabolic process
N5E84_06140	COG0561	phosphatase activity
N5E84_06160	COG2828	Protein conserved in bacteria
N5E84_06165	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
N5E84_06170	COG0372	Belongs to the citrate synthase family
N5E84_06175	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
N5E84_06205	COG0745	RESPONSE REGULATOR receiver
N5E84_06210	COG5002	protein histidine kinase activity
N5E84_06215	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
N5E84_06220	COG1902	pentaerythritol trinitrate reductase activity
N5E84_06225	COG3335	DDE superfamily endonuclease
N5E84_06230	COG0583	DNA-binding transcription factor activity
N5E84_06240	COG1129	ABC transporter
N5E84_06260	COG1342	Belongs to the UPF0251 family
N5E84_06270	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N5E84_06280	COG2207	Transcriptional regulator
N5E84_06285	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N5E84_06285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N5E84_06285	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N5E84_06300	COG0840	transmembrane signaling receptor activity
N5E84_06310	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
N5E84_06315	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N5E84_06320	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N5E84_06350	COG0840	transmembrane signaling receptor activity
N5E84_06370	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
N5E84_06385	COG4181	ATPase activity
N5E84_06390	COG0534	Mate efflux family protein
N5E84_06395	COG0702	epimerase
N5E84_06405	COG2814	Major facilitator Superfamily
N5E84_06410	COG1187	pseudouridine synthase activity
N5E84_06415	COG1061	Type III restriction enzyme res subunit
N5E84_06430	COG2205	protein histidine kinase activity
N5E84_06435	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
N5E84_06450	COG0513	Belongs to the DEAD box helicase family
N5E84_06460	COG0737	Belongs to the 5'-nucleotidase family
N5E84_06470	COG3313	Fe-S protein
N5E84_06480	COG4134	Bacterial extracellular solute-binding protein
N5E84_06485	COG4135	transport system, permease component
N5E84_06490	COG4136	ATPase activity
N5E84_06495	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
N5E84_06505	COG2200	EAL domain
N5E84_06515	COG0564	pseudouridine synthase activity
N5E84_06520	COG0733	neurotransmitter:sodium symporter activity
N5E84_06530	COG0626	cystathionine gamma-synthase activity
N5E84_06535	COG0519	Catalyzes the synthesis of GMP from XMP
N5E84_06550	COG1842	Phage shock protein A
N5E84_06555	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
N5E84_06570	COG4171	peptide transport system, permease
N5E84_06580	COG4172	Belongs to the ABC transporter superfamily
N5E84_06600	COG2433	Pfam Transposase IS66
N5E84_06610	COG3344	reverse transcriptase
N5E84_06635	COG4974	Belongs to the 'phage' integrase family
N5E84_06640	COG2433	Pfam Transposase IS66
N5E84_06690	COG1227	inorganic diphosphatase activity
N5E84_06700	COG0243	molybdopterin cofactor binding
N5E84_06705	COG3005	denitrification pathway
N5E84_06710	COG4459	periplasmic nitrate reductase
N5E84_06715	COG2116	formate transmembrane transporter activity
N5E84_06740	COG1434	Gram-negative-bacterium-type cell wall biogenesis
N5E84_06750	COG1435	thymidine kinase activity
N5E84_06755	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
N5E84_06760	COG1801	Protein of unknown function DUF72
N5E84_06770	COG0500	methyltransferase
N5E84_06775	COG4067	protein conserved in archaea
N5E84_06775	COG0189	ligase activity
N5E84_06790	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
N5E84_06795	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
N5E84_06805	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
N5E84_06810	COG1434	Gram-negative-bacterium-type cell wall biogenesis
N5E84_06815	COG0745	RESPONSE REGULATOR receiver
N5E84_06825	COG1609	Transcriptional regulator
N5E84_06830	COG3070	regulator of competence-specific genes
N5E84_06850	COG0297	glycogen (starch) synthase activity
N5E84_06855	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N5E84_06865	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N5E84_06880	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
N5E84_06885	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
N5E84_06890	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
N5E84_06895	COG0542	response to heat
N5E84_06900	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
N5E84_06905	COG1278	Cold shock
N5E84_06915	COG1187	pseudouridine synthase activity
N5E84_06920	COG0140	phosphoribosyl-ATP diphosphatase activity
N5E84_06920	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
N5E84_06925	COG0107	imidazoleglycerol-phosphate synthase activity
N5E84_06930	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
N5E84_06935	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
N5E84_06940	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
N5E84_06940	COG0131	Imidazoleglycerol-phosphate dehydratase
N5E84_06945	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
N5E84_06950	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
N5E84_06955	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
N5E84_06960	COG1757	Na H antiporter
N5E84_06965	COG2916	Histone family protein nucleoid-structuring protein H-NS
N5E84_06970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N5E84_06980	COG0482	sulfurtransferase activity
N5E84_06985	COG2915	High frequency lysogenization protein hflD homolog
N5E84_06990	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
N5E84_06995	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
N5E84_07005	COG4191	Histidine kinase
N5E84_07005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N5E84_07020	COG3070	regulator of competence-specific genes
N5E84_07030	COG2431	L-lysine efflux transmembrane transporter activity
N5E84_07040	COG0076	glutamate decarboxylase activity
N5E84_07045	COG1737	Transcriptional regulator
N5E84_07055	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
N5E84_07060	COG3273	potassium ion transport
N5E84_07060	COG2985	domain, Protein
N5E84_07065	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
N5E84_07075	COG0281	malic enzyme
N5E84_07085	COG2949	membrane
N5E84_07105	COG0492	ferredoxin-NADP+ reductase activity
N5E84_07110	COG4988	ABC transporter
N5E84_07115	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
N5E84_07120	COG1187	pseudouridine synthase activity
N5E84_07125	COG0009	L-threonylcarbamoyladenylate synthase
N5E84_07130	COG0613	PHP domain protein
N5E84_07140	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N5E84_07145	COG0512	Glutamine amidotransferase of anthranilate synthase
N5E84_07150	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
N5E84_07155	COG0134	indole-3-glycerol-phosphate synthase activity
N5E84_07155	COG0135	phosphoribosylanthranilate isomerase activity
N5E84_07160	COG0133	tryptophan synthase activity
N5E84_07165	COG0159	tryptophan synthase activity
N5E84_07190	COG2350	Protein conserved in bacteria
N5E84_07200	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
N5E84_07205	COG0583	DNA-binding transcription factor activity
N5E84_07230	COG1032	radical SAM domain protein
N5E84_07240	COG2268	Band 7 protein
N5E84_07250	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
N5E84_07265	COG0300	oxidoreductase activity
N5E84_07275	COG0501	Belongs to the peptidase M48B family
N5E84_07285	COG1674	ftsk spoiiie
N5E84_07290	COG1522	sequence-specific DNA binding
N5E84_07295	COG0686	Belongs to the AlaDH PNT family
N5E84_07305	COG0583	DNA-binding transcription factor activity
N5E84_07320	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
N5E84_07325	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
N5E84_07330	COG0776	regulation of translation
N5E84_07335	COG0539	negative regulation of cytoplasmic translation
N5E84_07340	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
N5E84_07345	COG1555	photosystem II stabilization
N5E84_07350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N5E84_07355	COG0776	regulation of translation
N5E84_07360	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
N5E84_07365	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
N5E84_07375	COG0544	peptidyl-prolyl cis-trans isomerase activity
N5E84_07390	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
N5E84_07395	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
N5E84_07400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
N5E84_07405	COG1653	transport
N5E84_07410	COG2205	protein histidine kinase activity
N5E84_07420	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
N5E84_07425	COG1760	l-serine dehydratase
N5E84_07435	COG0513	Belongs to the DEAD box helicase family
N5E84_07445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N5E84_07460	COG4628	conserved protein (DUF2132)
N5E84_07485	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N5E84_07490	COG0583	DNA-binding transcription factor activity
N5E84_07495	COG2951	lytic endotransglycosylase activity
N5E84_07500	COG3100	YcgL domain-containing protein
N5E84_07510	COG2894	cell division
N5E84_07515	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
N5E84_07520	COG3385	transposase activity
N5E84_07525	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
N5E84_07530	COG0318	PFAM AMP-dependent synthetase and ligase
N5E84_07535	COG0596	Alpha beta hydrolase
N5E84_07550	COG1214	PFAM Peptidase M22, glycoprotease
N5E84_07555	COG1199	ATP-dependent helicase activity
N5E84_07565	COG0788	formyltetrahydrofolate deformylase activity
N5E84_07570	COG0446	pyridine nucleotide-disulphide oxidoreductase
N5E84_07570	COG1902	pentaerythritol trinitrate reductase activity
N5E84_07575	COG0616	signal peptide processing
N5E84_07580	COG0252	asparaginase activity
N5E84_07585	COG3139	Protein of unknown function (DUF1315)
N5E84_07595	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N5E84_07605	COG3385	transposase activity
N5E84_07615	COG2226	methyltransferase
N5E84_07650	COG2433	Pfam Transposase IS66
N5E84_07710	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
N5E84_07725	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N5E84_07730	COG2832	Protein of unknown function (DUF454)
N5E84_07735	COG0745	RESPONSE REGULATOR receiver
N5E84_07740	COG0583	DNA-binding transcription factor activity
N5E84_07745	COG0778	Nitroreductase
N5E84_07750	COG1024	Enoyl-CoA hydratase
N5E84_07750	COG1250	3-hydroxyacyl-CoA dehydrogenase
N5E84_07755	COG0183	Belongs to the thiolase family
N5E84_07760	COG1595	DNA-templated transcription, initiation
N5E84_07770	COG2067	long-chain fatty acid transport protein
N5E84_07775	COG2067	long-chain fatty acid transport protein
N5E84_07780	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
N5E84_07785	COG2982	Protein involved in outer membrane biogenesis
N5E84_07790	COG0572	uridine kinase
N5E84_07795	COG0489	protein tyrosine kinase activity
N5E84_07800	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N5E84_07800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N5E84_07810	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
N5E84_07820	COG3335	DDE superfamily endonuclease
N5E84_07825	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
N5E84_07825	COG0617	tRNA 3'-terminal CCA addition
N5E84_07825	COG0517	IMP dehydrogenase activity
N5E84_07830	COG2199	diguanylate cyclase activity
N5E84_07835	COG0314	molybdopterin synthase activity
N5E84_07840	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
N5E84_07850	COG0521	Mo-molybdopterin cofactor biosynthetic process
N5E84_07855	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
N5E84_07860	COG0391	Required for morphogenesis under gluconeogenic growth conditions
N5E84_07865	COG2198	Histidine kinase
N5E84_07870	COG2204	response regulator
N5E84_07875	COG0556	nucleotide-excision repair
N5E84_07890	COG1028	Short-chain dehydrogenase reductase Sdr
N5E84_07895	COG2814	Major facilitator Superfamily
N5E84_07905	COG1902	pentaerythritol trinitrate reductase activity
N5E84_07910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N5E84_07915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N5E84_07925	COG0583	DNA-binding transcription factor activity
N5E84_07935	COG0657	acetylesterase activity
N5E84_07940	COG4771	TonB-dependent receptor
N5E84_07950	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
N5E84_07955	COG1028	Short-chain dehydrogenase reductase Sdr
N5E84_07960	COG1169	isochorismate synthase
N5E84_07965	COG1021	2,3-dihydroxybenzoate-AMP ligase
N5E84_07970	COG3433	isochorismatase activity
N5E84_07970	COG1535	isochorismatase
N5E84_07990	COG2382	esterase
N5E84_07995	COG1629	transport
N5E84_07995	COG4774	siderophore transport
N5E84_08005	COG4657	Part of a membrane complex involved in electron transport
N5E84_08010	COG2878	Part of a membrane complex involved in electron transport
N5E84_08015	COG4656	Part of a membrane complex involved in electron transport
N5E84_08020	COG4658	electron transport chain
N5E84_08025	COG4659	FMN binding
N5E84_08030	COG4660	Part of a membrane complex involved in electron transport
N5E84_08035	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
N5E84_08055	COG2433	Pfam Transposase IS66
N5E84_08080	COG0346	lactoylglutathione lyase activity
N5E84_08090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N5E84_08095	COG2056	Na+-H+ antiporter family
N5E84_08100	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
N5E84_08105	COG1286	toxin biosynthetic process
N5E84_08110	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
N5E84_08115	COG0285	dihydrofolate synthase activity
N5E84_08120	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
N5E84_08125	COG0101	tRNA pseudouridine synthase activity
N5E84_08135	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N5E84_08140	COG2190	(PTS) system
N5E84_08140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N5E84_08140	COG1263	PTS System
N5E84_08145	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
N5E84_08150	COG1940	carbohydrate kinase activity
N5E84_08150	COG1846	Transcriptional regulator
N5E84_08155	COG4651	solute:proton antiporter activity
N5E84_08155	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N5E84_08160	COG0367	asparagine synthase
N5E84_08170	COG3385	transposase activity
N5E84_08180	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
N5E84_08190	COG0326	Molecular chaperone. Has ATPase activity
N5E84_08195	COG3710	Transcriptional regulator
N5E84_08210	COG0622	Phosphoesterase
N5E84_08215	COG1090	epimerase
N5E84_08220	COG3118	belongs to the thioredoxin family
N5E84_08225	COG0330	HflC and HflK could
N5E84_08235	COG0789	Transcriptional regulator
N5E84_08240	COG3335	DDE superfamily endonuclease
N5E84_08255	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
N5E84_08260	COG3115	cell septum assembly
N5E84_08265	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
N5E84_08270	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N5E84_08275	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N5E84_08280	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N5E84_08285	COG2190	(PTS) system
N5E84_08290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N5E84_08295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N5E84_08300	COG1702	phosphate starvation-inducible protein PhoH
N5E84_08305	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
N5E84_08310	COG4535	Mg2 and Co2 transporter CorC
N5E84_08315	COG0815	Transfers the fatty acyl group on membrane lipoproteins
N5E84_08320	COG2888	peptidyl-tyrosine sulfation
N5E84_08325	COG0495	leucyl-tRNA aminoacylation
N5E84_08330	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
N5E84_08335	COG1466	dna polymerase III delta subunit
N5E84_08340	COG0799	negative regulation of ribosome biogenesis
N5E84_08345	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
N5E84_08350	COG0768	penicillin binding
N5E84_08355	COG0772	Belongs to the SEDS family
N5E84_08360	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
N5E84_08365	COG1686	Belongs to the peptidase S11 family
N5E84_08370	COG2921	Belongs to the UPF0250 family
N5E84_08375	COG0321	lipoyl(octanoyl) transferase activity
N5E84_08380	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N5E84_08410	COG1596	polysaccharide export
N5E84_08415	COG0489	protein tyrosine kinase activity
N5E84_08445	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
N5E84_08465	COG0438	transferase activity, transferring glycosyl groups
N5E84_08470	COG1215	transferase activity, transferring glycosyl groups
N5E84_08485	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
N5E84_08490	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
N5E84_08495	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N5E84_08500	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N5E84_08505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N5E84_08540	COG2205	protein histidine kinase activity
N5E84_08545	COG0745	RESPONSE REGULATOR receiver
N5E84_08550	COG0366	Alpha amylase catalytic
N5E84_08555	COG1263	PTS System
N5E84_08555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N5E84_08570	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
N5E84_08575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N5E84_08580	COG2011	ABC-type metal ion transport system permease component
N5E84_08585	COG1464	Belongs to the NlpA lipoprotein family
N5E84_08590	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
N5E84_08615	COG1611	Belongs to the LOG family
N5E84_08620	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N5E84_08625	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
N5E84_08630	COG2363	Small membrane protein
N5E84_08635	COG0583	DNA-binding transcription factor activity
N5E84_08640	COG0301	tRNA thio-modification
N5E84_08640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N5E84_08650	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
N5E84_08655	COG1722	exodeoxyribonuclease VII activity
N5E84_08660	COG0142	geranyltranstransferase activity
N5E84_08665	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
N5E84_08670	COG0564	pseudouridine synthase activity
N5E84_08675	COG3098	single-species biofilm formation
N5E84_08705	COG0257	Belongs to the bacterial ribosomal protein bL36 family
N5E84_08710	COG0254	rRNA binding
N5E84_08715	COG1720	tRNA m6t6A37 methyltransferase activity
N5E84_08720	COG0442	prolyl-tRNA aminoacylation
N5E84_08725	COG2979	Protein of unknown function (DUF533)
N5E84_08750	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
N5E84_08760	COG0590	tRNA wobble adenosine to inosine editing
N5E84_08765	COG0583	DNA-binding transcription factor activity
N5E84_08775	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
N5E84_08780	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
N5E84_08810	COG0484	heat shock protein binding
N5E84_08815	COG0443	Heat shock 70 kDa protein
N5E84_08820	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
N5E84_08825	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N5E84_08830	COG3033	Beta-eliminating lyase
N5E84_08835	COG0497	DNA recombination
N5E84_08840	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N5E84_08845	COG2914	Belongs to the UPF0125 (RnfH) family
N5E84_08850	COG2867	negative regulation of translational initiation
N5E84_08865	COG0582	viral genome integration into host DNA
N5E84_08875	COG2433	Pfam Transposase IS66
N5E84_08890	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N5E84_08895	COG0732	type I restriction modification DNA specificity domain
N5E84_08900	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
N5E84_08905	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
N5E84_08910	COG1715	Restriction endonuclease
N5E84_08925	COG2433	Pfam Transposase IS66
N5E84_08990	COG2003	Belongs to the UPF0758 family
N5E84_09005	COG1349	DNA-binding transcription factor activity
N5E84_09010	COG1349	DNA-binding transcription factor activity
N5E84_09020	COG2222	sugar isomerase
N5E84_09025	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N5E84_09030	COG3715	PTS system
N5E84_09035	COG3716	PTS system mannose fructose sorbose family IID component
N5E84_09040	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
N5E84_09055	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
N5E84_09060	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
N5E84_09065	COG1737	Transcriptional regulator
N5E84_09070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N5E84_09075	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
N5E84_09080	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
N5E84_09085	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
N5E84_09095	COG1940	carbohydrate kinase activity
N5E84_09100	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
N5E84_09105	COG4409	exo-alpha-(2->6)-sialidase activity
N5E84_09115	COG2003	Belongs to the UPF0758 family
N5E84_09155	COG0582	viral genome integration into host DNA
N5E84_09175	COG2433	Pfam Transposase IS66
N5E84_09215	COG2003	Belongs to the UPF0758 family
N5E84_09270	COG0556	nucleotide-excision repair
N5E84_09300	COG3964	amidohydrolase
N5E84_09315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N5E84_09315	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
N5E84_09340	COG1115	amino acid carrier protein
N5E84_09345	COG1584	GPR1 FUN34 yaaH family protein
N5E84_09355	COG0351	phosphomethylpyrimidine kinase
N5E84_09360	COG0518	GMP synthase (glutamine-hydrolyzing) activity
N5E84_09360	COG0519	Catalyzes the synthesis of GMP from XMP
N5E84_09365	COG0517	IMP dehydrogenase activity
N5E84_09365	COG0516	GMP reductase activity
N5E84_09385	COG1160	GTP binding
N5E84_09390	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N5E84_09395	COG2976	Protein conserved in bacteria
N5E84_09400	COG0124	histidyl-tRNA synthetase
N5E84_09405	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
N5E84_09410	COG1426	Protein conserved in bacteria
N5E84_09425	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
N5E84_09430	COG2975	iron-sulfur cluster assembly
N5E84_09435	COG0633	Ferredoxin
N5E84_09440	COG0443	Heat shock 70 kDa protein
N5E84_09450	COG0316	Belongs to the HesB IscA family
N5E84_09455	COG0822	iron-sulfur transferase activity
N5E84_09465	COG1959	2 iron, 2 sulfur cluster binding
N5E84_09470	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
N5E84_09475	COG0483	inositol monophosphate 1-phosphatase activity
N5E84_09480	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N5E84_09485	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N5E84_09490	COG1862	Preprotein translocase
N5E84_09495	COG0343	queuine tRNA-ribosyltransferase activity
N5E84_09505	COG0517	IMP dehydrogenase activity
N5E84_09515	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
N5E84_09520	COG0583	DNA-binding transcription factor activity
N5E84_09525	COG0450	alkyl hydroperoxide reductase
N5E84_09530	COG3142	Participates in the control of copper homeostasis
N5E84_09535	COG0704	Plays a role in the regulation of phosphate uptake
N5E84_09540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N5E84_09545	COG0581	inorganic phosphate transmembrane transporter activity
N5E84_09555	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
N5E84_09560	COG0248	Ppx GppA phosphatase
N5E84_09570	COG5002	protein histidine kinase activity
N5E84_09575	COG0745	RESPONSE REGULATOR receiver
N5E84_09585	COG0826	peptidase U32
N5E84_09590	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
N5E84_09630	COG0542	response to heat
N5E84_09635	COG1496	oxidoreductase activity
N5E84_09640	COG0564	pseudouridine synthase activity
N5E84_09645	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N5E84_09650	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
N5E84_09655	COG0077	Prephenate dehydratase
N5E84_09655	COG1605	Chorismate mutase
N5E84_09660	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
N5E84_09665	COG5001	Diguanylate cyclase
N5E84_09670	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
N5E84_09675	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
N5E84_09685	COG0488	(ABC) transporter
N5E84_09695	COG1605	Chorismate mutase
N5E84_09695	COG0287	Prephenate dehydrogenase
N5E84_09700	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
N5E84_09705	COG3275	phosphorelay sensor kinase activity
N5E84_09710	COG3279	Response regulator of the LytR AlgR family
N5E84_09720	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
N5E84_09725	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
N5E84_09740	COG1966	Carbon starvation protein
N5E84_09745	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
N5E84_09750	COG1047	Peptidyl-prolyl cis-trans
N5E84_09755	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
N5E84_09765	COG0196	riboflavin kinase activity
N5E84_09770	COG0728	peptidoglycan biosynthetic process
N5E84_09775	COG0268	Binds directly to 16S ribosomal RNA
N5E84_09780	COG0640	Transcriptional regulator
N5E84_09785	COG0583	DNA-binding transcription factor activity
N5E84_09790	COG1283	sodium-dependent phosphate transmembrane transporter activity
N5E84_09795	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
N5E84_09805	COG0730	response to heat
N5E84_09810	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
N5E84_09815	COG0494	nUDIX hydrolase
N5E84_09825	COG0667	Aldo Keto reductase
N5E84_09835	COG2204	response regulator
N5E84_09840	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
N5E84_09855	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
N5E84_09860	COG0513	Belongs to the DEAD box helicase family
N5E84_09885	COG3153	acetyltransferase
N5E84_09890	COG3154	lipid carrier protein
N5E84_09900	COG0826	peptidase U32
N5E84_09905	COG0826	peptidase U32
N5E84_09915	COG1846	Transcriptional regulator
N5E84_09930	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
N5E84_09935	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
N5E84_09950	COG0195	Participates in both transcription termination and antitermination
N5E84_09955	COG0779	Required for maturation of 30S ribosomal subunits
N5E84_09970	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N5E84_09975	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N5E84_09980	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
N5E84_09985	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N5E84_09990	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
N5E84_09995	COG1534	Rna-binding protein
N5E84_10000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N5E84_10005	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
N5E84_10010	COG2027	D-alanyl-D-alanine carboxypeptidase
N5E84_10015	COG2239	Acts as a magnesium transporter
N5E84_10020	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N5E84_10025	COG0739	heme binding
N5E84_10040	COG0316	Belongs to the HesB IscA family
N5E84_10045	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
N5E84_10050	COG0628	permease
N5E84_10060	COG2205	protein histidine kinase activity
N5E84_10060	COG0784	Response regulator, receiver
N5E84_10065	COG0747	negative chemotaxis
N5E84_10075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N5E84_10080	COG0444	Belongs to the ABC transporter superfamily
N5E84_10085	COG4608	Belongs to the ABC transporter superfamily
N5E84_10095	COG2971	BadF BadG BcrA BcrD
N5E84_10110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N5E84_10125	COG1840	ABC-type Fe3 transport system, periplasmic component
N5E84_10130	COG0004	ammonium transporteR
N5E84_10140	COG3112	Uncharacterised protein family (UPF0231)
N5E84_10145	COG3835	regulator
N5E84_10150	COG2610	gluconate transmembrane transporter activity
N5E84_10155	COG1929	Belongs to the glycerate kinase type-1 family
N5E84_10160	COG1049	propionate catabolic process, 2-methylcitrate cycle
N5E84_10165	COG1752	Esterase of the alpha-beta hydrolase superfamily
N5E84_10170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N5E84_10175	COG1643	Atp-dependent helicase
N5E84_10180	COG1489	DNA binding
N5E84_10185	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N5E84_10190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N5E84_10200	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
N5E84_10210	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
N5E84_10230	COG4974	Belongs to the 'phage' integrase family
N5E84_10255	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N5E84_10280	COG1131	(ABC) transporter
N5E84_10285	COG0659	secondary active sulfate transmembrane transporter activity
N5E84_10290	COG0288	reversible hydration of carbon dioxide
N5E84_10305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N5E84_10310	COG0508	dehydrogenase complex catalyzes the overall conversion of
N5E84_10315	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
N5E84_10320	COG2186	Transcriptional regulator
N5E84_10325	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N5E84_10330	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N5E84_10335	COG4974	Belongs to the 'phage' integrase family
N5E84_10340	COG0716	FMN binding
N5E84_10350	COG0157	Belongs to the NadC ModD family
N5E84_10355	COG4969	Belongs to the N-Me-Phe pilin family
N5E84_10360	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N5E84_10365	COG1459	type II secretion system
N5E84_10375	COG0237	dephospho-CoA kinase activity
N5E84_10380	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
N5E84_10390	COG0335	large ribosomal subunit rRNA binding
N5E84_10395	COG0336	Belongs to the RNA methyltransferase TrmD family
N5E84_10400	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
N5E84_10405	COG0228	four-way junction DNA binding
N5E84_10410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
N5E84_10415	COG4137	Cytochrome C assembly protein
N5E84_10420	COG4536	flavin adenine dinucleotide binding
N5E84_10425	COG1854	S-ribosylhomocysteine lyase activity
N5E84_10435	COG0612	Peptidase, M16
N5E84_10440	COG1238	metal cluster binding
N5E84_10450	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
N5E84_10455	COG0511	ligase activity, forming carbon-carbon bonds
N5E84_10455	COG5016	pyruvate
N5E84_10460	COG3630	sodium ion export across plasma membrane
N5E84_10505	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
N5E84_10510	COG0527	aspartate kinase activity
N5E84_10515	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
N5E84_10520	COG2137	regulation of response to DNA damage stimulus
N5E84_10525	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
N5E84_10530	COG1546	Belongs to the CinA family
N5E84_10535	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
N5E84_10540	COG4208	sulfate ABC transporter
N5E84_10550	COG4150	thiosulfate binding
N5E84_10560	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
N5E84_10565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N5E84_10570	COG1388	LysM domain
N5E84_10570	COG4942	peptidase
N5E84_10575	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
N5E84_10580	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
N5E84_10585	COG0585	pseudouridine synthase activity
N5E84_10590	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
N5E84_10595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
N5E84_10600	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
N5E84_10605	COG1968	undecaprenyl-diphosphatase activity
N5E84_10610	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
N5E84_10615	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
N5E84_10620	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
N5E84_10630	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
N5E84_10635	COG0828	Belongs to the bacterial ribosomal protein bS21 family
N5E84_10640	COG1610	YqeY-like protein
N5E84_10645	COG0358	DNA primase activity
N5E84_10695	COG3501	Rhs element vgr protein
N5E84_10715	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
N5E84_10720	COG0583	DNA-binding transcription factor activity
N5E84_10730	COG3335	DDE superfamily endonuclease
N5E84_10795	COG1349	DNA-binding transcription factor activity
N5E84_10805	COG3385	transposase activity
N5E84_10810	COG3706	GGDEF domain
N5E84_10830	COG0668	transmembrane transport
N5E84_10835	COG0191	fructose-bisphosphate aldolase activity
N5E84_10840	COG0126	phosphoglycerate kinase activity
N5E84_10845	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N5E84_10850	COG4771	TonB-dependent receptor
N5E84_10855	COG0583	DNA-binding transcription factor activity
N5E84_10860	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
N5E84_10865	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
N5E84_10870	COG3091	SprT-like family
N5E84_10875	COG2356	endonuclease I
N5E84_10880	COG1385	rRNA (uridine-N3-)-methyltransferase activity
N5E84_10890	COG1678	Uncharacterized ACR, COG1678
N5E84_10895	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
N5E84_10910	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
N5E84_10915	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N5E84_10935	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
N5E84_10940	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N5E84_10945	COG2066	Belongs to the glutaminase family
N5E84_10960	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
N5E84_10965	COG0741	lytic transglycosylase activity
N5E84_11015	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
N5E84_11020	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
N5E84_11025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N5E84_11030	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
N5E84_11035	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
N5E84_11040	COG2967	ApaG domain
N5E84_11055	COG3610	response to peptide
N5E84_11060	COG2966	Psort location CytoplasmicMembrane, score
N5E84_11065	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
N5E84_11070	COG0211	Belongs to the bacterial ribosomal protein bL27 family
N5E84_11075	COG0261	This protein binds to 23S rRNA in the presence of protein L20
N5E84_11080	COG0142	geranyltranstransferase activity
N5E84_11085	COG3385	transposase activity
N5E84_11090	COG0531	amino acid
N5E84_11100	COG1438	arginine binding
N5E84_11105	COG2358	TRAP transporter, solute receptor (TAXI family
N5E84_11115	COG0589	response to stress
N5E84_11135	COG2235	arginine
N5E84_11140	COG0312	modulator of DNA gyrase
N5E84_11145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N5E84_11150	COG3164	Protein of unknown function
N5E84_11160	COG0424	maF-like protein
N5E84_11165	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
N5E84_11170	COG1792	Involved in formation and maintenance of cell shape
N5E84_11175	COG1077	Cell shape determining protein MreB Mrl
N5E84_11205	COG2165	general secretion pathway protein
N5E84_11210	COG2165	general secretion pathway protein
N5E84_11220	COG1459	type II secretion system
N5E84_11225	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N5E84_11235	COG3267	Type II secretory pathway component ExeA
N5E84_11235	COG3409	Peptidoglycan-binding domain 1 protein
N5E84_11260	COG2199	diguanylate cyclase activity
N5E84_11260	COG2200	EAL domain
N5E84_11265	COG0629	single-stranded DNA binding
N5E84_11280	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
N5E84_11300	COG2433	Pfam Transposase IS66
N5E84_11305	COG2239	Acts as a magnesium transporter
N5E84_11315	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
N5E84_11320	COG0527	aspartate kinase activity
N5E84_11325	COG1410	methionine synthase
N5E84_11325	COG0646	methionine synthase
N5E84_11400	COG0175	sulfate reduction
N5E84_11410	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N5E84_11430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N5E84_11435	COG0735	belongs to the Fur family
N5E84_11445	COG0166	Belongs to the GPI family
N5E84_11450	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N5E84_11465	COG0359	binds to the 23S rRNA
N5E84_11475	COG2965	DNA replication, synthesis of RNA primer
N5E84_11480	COG0360	Binds together with S18 to 16S ribosomal RNA
N5E84_11485	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
N5E84_11490	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
N5E84_11495	COG0049	tRNA binding
N5E84_11510	COG2923	Belongs to the DsrF TusC family
N5E84_11515	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
N5E84_11520	COG2964	Protein conserved in bacteria
N5E84_11525	COG0545	Peptidyl-prolyl cis-trans isomerase
N5E84_11540	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
N5E84_11545	COG0330	HflC and HflK could
N5E84_11550	COG0330	HflC and HflK could
N5E84_11555	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
N5E84_11565	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
N5E84_11570	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
N5E84_11575	COG0860	N-Acetylmuramoyl-L-alanine amidase
N5E84_11580	COG0802	atpase or kinase
N5E84_11585	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
N5E84_11640	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
N5E84_11645	COG1162	GTPase activity
N5E84_11655	COG0471	metal ion transport
N5E84_11655	COG0490	domain, Protein
N5E84_11670	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
N5E84_11675	COG4942	peptidase
N5E84_11690	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
N5E84_11695	COG2816	NAD+ diphosphatase activity
N5E84_11700	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
N5E84_11705	COG3385	transposase activity
N5E84_11710	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
N5E84_11715	COG0085	RNA polymerase activity
N5E84_11720	COG0222	ribosome binding
N5E84_11725	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
N5E84_11740	COG0250	Participates in transcription elongation, termination and antitermination
N5E84_11745	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N5E84_11750	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
N5E84_11775	COG1072	(Pantothenic acid kinase))
N5E84_11780	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
N5E84_11780	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
N5E84_11785	COG0812	UDP-N-acetylmuramate dehydrogenase activity
N5E84_11795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N5E84_11870	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
N5E84_11885	COG3118	belongs to the thioredoxin family
N5E84_11895	COG0248	Ppx GppA phosphatase
N5E84_11900	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
N5E84_11905	COG0194	GDP metabolic process
N5E84_11910	COG1758	RNA polymerase activity
N5E84_11915	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N5E84_11920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
N5E84_11925	COG2233	PERMEase
N5E84_11955	COG0583	DNA-binding transcription factor activity
N5E84_11975	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N5E84_11980	COG2183	response to ionizing radiation
N5E84_11990	COG0596	Alpha beta hydrolase
N5E84_11995	COG1040	competence protein
N5E84_12000	COG0316	Belongs to the HesB IscA family
N5E84_12000	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
N5E84_12005	COG0494	nUDIX hydrolase
N5E84_12010	COG1218	3'(2'),5'-bisphosphate nucleotidase
N5E84_12020	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
N5E84_12025	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
N5E84_12030	COG3156	type II secretion system protein K
N5E84_12035	COG4795	General secretion pathway protein
N5E84_12040	COG2165	general secretion pathway protein
N5E84_12045	COG2165	general secretion pathway protein
N5E84_12050	COG2165	general secretion pathway protein
N5E84_12055	COG1459	type II secretion system
N5E84_12060	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N5E84_12070	COG3031	protein transport across the cell outer membrane
N5E84_12075	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
N5E84_12080	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
N5E84_12085	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
N5E84_12095	COG0456	acetyltransferase
N5E84_12100	COG1490	D-aminoacyl-tRNA deacylase activity
N5E84_12105	COG1295	ribonuclease BN
N5E84_12110	COG1217	gtp-binding protein TYPA
N5E84_12115	COG0174	glutamine synthetase
N5E84_12125	COG3852	Histidine kinase
N5E84_12135	COG3300	MHYT domain
N5E84_12135	COG5001	Diguanylate cyclase
N5E84_12140	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
N5E84_12175	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N5E84_12185	COG4206	TonB-dependent receptor
N5E84_12210	COG0210	DNA helicase
N5E84_12220	COG2433	Pfam Transposase IS66
N5E84_12245	COG2433	Pfam Transposase IS66
N5E84_12280	COG3335	DDE superfamily endonuclease
N5E84_12300	COG0742	ribosomal rna small subunit methyltransferase
N5E84_12305	COG0552	protein localization to endoplasmic reticulum
N5E84_12310	COG2884	Cell division ATP-binding protein ftsE
N5E84_12315	COG2177	Part of the ABC transporter FtsEX involved in
N5E84_12320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N5E84_12330	COG0705	Rhomboid family
N5E84_12335	COG1580	Controls the rotational direction of flagella during chemotaxis
N5E84_12340	COG3161	chorismate lyase activity
N5E84_12350	COG2937	Belongs to the GPAT DAPAT family
N5E84_12355	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
N5E84_12365	COG0534	Mate efflux family protein
N5E84_12370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N5E84_12390	COG3250	beta-galactosidase activity
N5E84_12415	COG2433	Pfam Transposase IS66
N5E84_12450	COG0328	RNA-DNA hybrid ribonuclease activity
N5E84_12455	COG2433	Pfam Transposase IS66
N5E84_12505	COG2003	Belongs to the UPF0758 family
N5E84_12535	COG2433	Pfam Transposase IS66
N5E84_12590	COG2433	Pfam Transposase IS66
N5E84_12630	COG0783	Belongs to the Dps family
N5E84_12635	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
N5E84_12640	COG1280	lysine exporter protein (LysE YggA)
N5E84_12645	COG2267	carboxylic ester hydrolase activity
N5E84_12650	COG0561	phosphatase activity
N5E84_12660	COG3148	PFAM DTW domain containing protein
N5E84_12665	COG1011	Hydrolase
N5E84_12670	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
N5E84_12680	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
N5E84_12685	COG0019	diaminopimelate decarboxylase activity
N5E84_12710	COG1587	Uroporphyrinogen-III synthase
N5E84_12715	COG2959	enzyme of heme biosynthesis
N5E84_12720	COG3071	HemY protein
N5E84_12750	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
N5E84_12760	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
N5E84_12765	COG0408	coproporphyrinogen oxidase activity
N5E84_12770	COG0009	L-threonylcarbamoyladenylate synthase
N5E84_12775	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
N5E84_12780	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
N5E84_12785	COG0551	DNA topoisomerase type I activity
N5E84_12790	COG2922	Belongs to the Smg family
N5E84_12795	COG0758	DNA mediated transformation
N5E84_12800	COG1652	LysM domain
N5E84_12805	COG0242	peptide deformylase activity
N5E84_12810	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
N5E84_12815	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
N5E84_12815	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N5E84_12820	COG0569	domain protein
N5E84_12825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N5E84_12835	COG1272	protein, Hemolysin III
N5E84_12845	COG3084	Protein conserved in bacteria
N5E84_12855	COG3385	transposase activity
N5E84_12860	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N5E84_12865	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N5E84_12895	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
N5E84_12895	COG0784	Response regulator, receiver
N5E84_12930	COG2081	HI0933 family
N5E84_12945	COG1528	Iron-storage protein
N5E84_12950	COG0589	response to stress
N5E84_12965	COG0742	ribosomal rna small subunit methyltransferase
N5E84_12970	COG1522	sequence-specific DNA binding
N5E84_12990	COG0006	proline dipeptidase activity
N5E84_12990	COG0006	proline dipeptidase activity
N5E84_12995	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
N5E84_13000	COG2022	thiamine diphosphate biosynthetic process
N5E84_13005	COG2104	thiamine diphosphate biosynthetic process
N5E84_13015	COG0352	thiamine-phosphate diphosphorylase activity
N5E84_13070	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
N5E84_13075	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N5E84_13080	COG1739	Uncharacterized protein family UPF0029
N5E84_13090	COG0183	Belongs to the thiolase family
N5E84_13095	COG0583	DNA-binding transcription factor activity
N5E84_13100	COG2814	Major facilitator Superfamily
N5E84_13110	COG0355	proton-transporting ATP synthase activity, rotational mechanism
N5E84_13115	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
N5E84_13120	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
N5E84_13125	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
N5E84_13130	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
N5E84_13135	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
N5E84_13150	COG3312	ion transport
N5E84_13155	COG1475	DNA binding
N5E84_13160	COG1192	Involved in chromosome partitioning
N5E84_13170	COG0445	tRNA wobble uridine modification
N5E84_13175	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N5E84_13185	COG0706	membrane insertase activity
N5E84_13205	COG1126	abc transporter atp-binding protein
N5E84_13225	COG0592	DNA-directed DNA polymerase activity
N5E84_13230	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N5E84_13235	COG0187	DNA topoisomerase II activity
N5E84_13245	COG0071	Belongs to the small heat shock protein (HSP20) family
N5E84_13260	COG0752	glycyl-tRNA synthetase alpha subunit
N5E84_13265	COG2119	membrane
N5E84_13275	COG0425	Belongs to the sulfur carrier protein TusA family
N5E84_13290	COG0604	alcohol dehydrogenase
N5E84_13305	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N5E84_13310	COG3978	acetolactate synthase activity
N5E84_13345	COG2433	Pfam Transposase IS66
N5E84_13420	COG0697	spore germination
N5E84_13425	COG1322	Protein conserved in bacteria
N5E84_13430	COG2226	methyltransferase
N5E84_13440	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
N5E84_13445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N5E84_13450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N5E84_13455	COG0805	protein transport
N5E84_13460	COG0084	hydrolase, TatD family'
N5E84_13470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N5E84_13470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N5E84_13490	COG3078	GTPase activator activity
N5E84_13510	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
N5E84_13515	COG2960	long-chain fatty acid transporting porin activity
N5E84_13520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N5E84_13525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N5E84_13530	COG1309	transcriptional regulator
N5E84_13580	COG0601	transmembrane transport
N5E84_13585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N5E84_13645	COG1132	(ABC) transporter
N5E84_13650	COG4774	siderophore transport
N5E84_13660	COG4607	ABC-type enterochelin transport system periplasmic component
N5E84_13665	COG4605	iron ion homeostasis
N5E84_13675	COG2433	Pfam Transposase IS66
N5E84_13710	COG2433	Pfam Transposase IS66
N5E84_13750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N5E84_13755	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
N5E84_13760	COG0339	signal peptide processing
N5E84_13765	COG0210	DNA helicase
N5E84_13770	COG1280	lysine exporter protein (LysE YggA)
N5E84_13780	COG2962	Rard protein
N5E84_13785	COG0514	ATP-dependent DNA helicase (RecQ)
N5E84_13805	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
N5E84_13810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N5E84_13810	COG1263	PTS System
N5E84_13815	COG1132	(ABC) transporter
N5E84_13820	COG4774	siderophore transport
N5E84_13825	COG1120	ATPase activity
N5E84_13840	COG2862	Uncharacterized protein family, UPF0114
N5E84_13845	COG0612	Peptidase, M16
N5E84_13865	COG1561	YicC-like family, N-terminal region
N5E84_13870	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
N5E84_13875	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
N5E84_13880	COG1560	Kdo2-lipid A biosynthetic process
N5E84_13885	COG1560	Kdo2-lipid A biosynthetic process
N5E84_13890	COG1309	transcriptional regulator
N5E84_13895	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
N5E84_13900	COG2003	Belongs to the UPF0758 family
N5E84_13905	COG0227	Belongs to the bacterial ribosomal protein bL28 family
N5E84_13910	COG0267	Belongs to the bacterial ribosomal protein bL33 family
N5E84_13920	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
N5E84_13925	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
N5E84_13930	COG0859	PFAM glycosyl transferase family 9
N5E84_13935	COG0463	Glycosyl transferase, family 2
N5E84_13940	COG0859	PFAM glycosyl transferase family 9
N5E84_13945	COG3642	lipopolysaccharide core region biosynthetic process
N5E84_13950	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
N5E84_13950	COG2755	lipolytic protein G-D-S-L family
N5E84_13980	COG1519	Transferase
N5E84_13995	COG0859	PFAM glycosyl transferase family 9
N5E84_14005	COG3307	-O-antigen
N5E84_14040	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
N5E84_14065	COG0367	asparagine synthase
N5E84_14070	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
N5E84_14130	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
N5E84_14140	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N5E84_14175	COG2433	Pfam Transposase IS66
N5E84_14185	COG4372	Transposase
N5E84_14200	COG0668	transmembrane transport
N5E84_14205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N5E84_14210	COG3068	Protein conserved in bacteria
N5E84_14220	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N5E84_14255	COG1253	flavin adenine dinucleotide binding
N5E84_14260	COG0776	regulation of translation
N5E84_14270	COG0151	Belongs to the GarS family
N5E84_14275	COG0138	bifunctional purine biosynthesis protein purh
N5E84_14280	COG0789	Transcriptional regulator
N5E84_14285	COG0840	transmembrane signaling receptor activity
N5E84_14290	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
N5E84_14295	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N5E84_14300	COG2264	protein methyltransferase activity
N5E84_14305	COG0439	Biotin carboxylase
N5E84_14310	COG0511	ligase activity, forming carbon-carbon bonds
N5E84_14315	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
N5E84_14320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N5E84_14340	COG0784	Response regulator, receiver
N5E84_14340	COG2198	Histidine kinase
N5E84_14340	COG2205	protein histidine kinase activity
N5E84_14345	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N5E84_14365	COG4232	protein-disulfide reductase activity
N5E84_14370	COG1438	arginine binding
N5E84_14375	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
N5E84_14380	COG0540	Belongs to the ATCase OTCase family
N5E84_14385	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
N5E84_14390	COG0549	Belongs to the carbamate kinase family
N5E84_14400	COG3335	DDE superfamily endonuclease
N5E84_14405	COG1288	antiporter activity
N5E84_14410	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
N5E84_14415	COG1027	Aspartate ammonia-lyase
N5E84_14420	COG3030	protein affecting phage T7 exclusion by the F plasmid
N5E84_14425	COG1278	Cold shock
N5E84_14430	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
N5E84_14435	COG2205	protein histidine kinase activity
N5E84_14440	COG0745	RESPONSE REGULATOR receiver
N5E84_14450	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
N5E84_14455	COG0205	6-phosphofructokinase activity
N5E84_14460	COG1494	fructose-1,6-bisphosphatase
N5E84_14465	COG3074	FtsZ-dependent cytokinesis
N5E84_14470	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
N5E84_14475	COG3385	transposase activity
N5E84_14480	COG0527	aspartate kinase activity
N5E84_14480	COG0460	homoserine dehydrogenase
N5E84_14485	COG0626	cystathionine gamma-synthase activity
N5E84_14495	COG0281	malic enzyme
N5E84_14505	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
N5E84_14510	COG1609	Transcriptional regulator
N5E84_14520	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
N5E84_14525	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
N5E84_14530	COG1575	Belongs to the MenA family. Type 1 subfamily
N5E84_14535	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N5E84_14610	COG0534	Mate efflux family protein
N5E84_14640	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
N5E84_14645	COG0459	protein refolding
N5E84_14670	COG1509	lysine 2,3-aminomutase activity
N5E84_14675	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
N5E84_14685	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
N5E84_14690	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
N5E84_14695	COG1053	succinate dehydrogenase
N5E84_14700	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
N5E84_14705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N5E84_14715	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
N5E84_14720	COG1045	serine acetyltransferase
N5E84_14730	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
N5E84_14735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N5E84_14740	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
N5E84_14745	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
N5E84_14750	COG0137	argininosuccinate synthase activity
N5E84_14755	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
N5E84_14755	COG0165	Argininosuccinate lyase
N5E84_14765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N5E84_14770	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
N5E84_14770	COG0678	peroxiredoxin activity
N5E84_14780	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
N5E84_14810	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
N5E84_14815	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
N5E84_14825	COG0338	D12 class N6 adenine-specific DNA methyltransferase
N5E84_14830	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
N5E84_14835	COG0546	phosphoglycolate phosphatase activity
N5E84_14840	COG0180	Tryptophanyl-tRNA synthetase
N5E84_14855	COG0583	DNA-binding transcription factor activity
N5E84_14865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N5E84_14880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N5E84_14890	COG1012	belongs to the aldehyde dehydrogenase family
N5E84_14900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N5E84_14905	COG3954	Phosphoribulokinase
N5E84_14915	COG0429	hydrolase of the alpha beta-hydrolase fold
N5E84_14925	COG0488	(ABC) transporter
N5E84_14930	COG2249	NAD(P)H dehydrogenase (quinone) activity
N5E84_14940	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
N5E84_14945	COG1047	Peptidyl-prolyl cis-trans
N5E84_14955	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
N5E84_14960	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
N5E84_14965	COG0557	exoribonuclease II activity
N5E84_14970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N5E84_14975	COG0051	transcription antitermination factor activity, RNA binding
N5E84_14980	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
N5E84_14985	COG0088	Forms part of the polypeptide exit tunnel
N5E84_14995	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
N5E84_15000	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
N5E84_15015	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
N5E84_15025	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
N5E84_15035	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
N5E84_15040	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
N5E84_15045	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
N5E84_15050	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
N5E84_15055	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
N5E84_15065	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
N5E84_15070	COG1841	ribosomal large subunit assembly
N5E84_15075	COG0200	Binds to the 23S rRNA
N5E84_15080	COG0201	protein transport
N5E84_15085	COG0257	Belongs to the bacterial ribosomal protein bL36 family
N5E84_15090	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
N5E84_15095	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
N5E84_15100	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
N5E84_15105	COG0202	RNA polymerase activity
N5E84_15110	COG0203	ribosomal protein L17
N5E84_15115	COG0545	Peptidyl-prolyl cis-trans isomerase
N5E84_15120	COG3266	domain, Protein
N5E84_15120	COG3061	Opacity-associated protein A
N5E84_15125	COG2153	protein acetylation
N5E84_15130	COG0513	Belongs to the DEAD box helicase family
N5E84_15155	COG3335	DDE superfamily endonuclease
N5E84_15185	COG1648	precorrin-2 dehydrogenase activity
N5E84_15185	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N5E84_15190	COG0175	sulfate reduction
N5E84_15195	COG2895	sulfate adenylyltransferase (ATP) activity
N5E84_15200	COG0529	Catalyzes the synthesis of activated sulfate
N5E84_15235	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
N5E84_15240	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N5E84_15245	COG0729	surface antigen
N5E84_15260	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
N5E84_15265	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
N5E84_15270	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N5E84_15285	COG1178	ABC-type Fe3 transport system permease component
N5E84_15290	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
N5E84_15295	COG3028	Belongs to the UPF0307 family
N5E84_15300	COG0312	modulator of DNA gyrase
N5E84_15305	COG2239	Acts as a magnesium transporter
N5E84_15310	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N5E84_15315	COG1660	Displays ATPase and GTPase activities
N5E84_15320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N5E84_15325	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
N5E84_15335	COG1137	ATPase activity
N5E84_15340	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
N5E84_15355	COG0517	IMP dehydrogenase activity
N5E84_15355	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
N5E84_15380	COG2854	intermembrane phospholipid transfer
N5E84_15390	COG5007	Belongs to the BolA IbaG family
N5E84_15395	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N5E84_15400	COG0204	Acyl-transferase
N5E84_15415	COG0251	oxidation-reduction process
N5E84_15420	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
N5E84_15455	COG0564	pseudouridine synthase activity
N5E84_15465	COG0525	valine-tRNA ligase activity
N5E84_15470	COG2927	DNA polymerase III (CHI subunit)
N5E84_15505	COG3328	transposase activity
N5E84_15565	COG0473	3-isopropylmalate dehydrogenase activity
N5E84_15570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N5E84_15630	COG1648	precorrin-2 dehydrogenase activity
N5E84_15630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N5E84_15640	COG2895	sulfate adenylyltransferase (ATP) activity
N5E84_15645	COG2895	sulfate adenylyltransferase (ATP) activity
N5E84_15650	COG2895	sulfate adenylyltransferase (ATP) activity
N5E84_15655	COG2895	sulfate adenylyltransferase (ATP) activity
N5E84_15695	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
N5E84_15700	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N5E84_15705	COG0729	surface antigen
N5E84_15710	COG2911	Protein conserved in bacteria
N5E84_15715	COG2105	PFAM AIG2 family protein
N5E84_15720	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
N5E84_15725	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
N5E84_15740	COG4143	(ABC) transporter
N5E84_15775	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N5E84_15780	COG1660	Displays ATPase and GTPase activities
N5E84_15785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N5E84_15790	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
N5E84_15800	COG1137	ATPase activity
N5E84_15805	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
N5E84_15820	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
N5E84_15820	COG0517	IMP dehydrogenase activity
N5E84_15875	COG0561	phosphatase activity
N5E84_15880	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
N5E84_15885	COG3623	hexulose-6-phosphate isomerase
N5E84_15905	COG1132	(ABC) transporter
N5E84_15915	COG0671	phosphoesterase, PA-phosphatase related
N5E84_15945	COG1131	(ABC) transporter
N5E84_15950	COG2188	Transcriptional regulator
N5E84_15960	COG3335	DDE superfamily endonuclease
N5E84_15965	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
N5E84_15970	COG0471	metal ion transport
N5E84_15995	COG2433	Pfam Transposase IS66
N5E84_16040	COG3501	Rhs element vgr protein
N5E84_16040	COG3409	Peptidoglycan-binding domain 1 protein
N5E84_16065	COG3829	transcription factor binding
N5E84_16090	COG3335	DDE superfamily endonuclease
N5E84_16130	COG3335	DDE superfamily endonuclease
N5E84_16140	COG3335	DDE superfamily endonuclease
N5E84_16145	COG0564	pseudouridine synthase activity
N5E84_16155	COG0745	RESPONSE REGULATOR receiver
N5E84_16170	COG1309	transcriptional regulator
N5E84_16175	COG2130	NADP-dependent
N5E84_16185	COG1328	CTP reductase activity
N5E84_16190	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
N5E84_16200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N5E84_16205	COG0251	oxidation-reduction process
N5E84_16210	COG0513	Belongs to the DEAD box helicase family
N5E84_16230	COG1175	transmembrane transport
N5E84_16240	COG3842	ATPase activity
N5E84_16255	COG1131	(ABC) transporter
N5E84_16260	COG0842	Transport permease protein
N5E84_16265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N5E84_16270	COG3046	protein related to deoxyribodipyrimidine photolyase
N5E84_16280	COG1846	Transcriptional regulator
N5E84_16285	COG1566	PFAM secretion protein HlyD family protein
N5E84_16305	COG2259	Doxx family
N5E84_16310	COG1301	dicarboxylic acid transport
N5E84_16315	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
N5E84_16325	COG3722	fumarate hydratase activity
N5E84_16330	COG0246	Mannitol dehydrogenase
N5E84_16335	COG2213	PTS system mannitol-specific
N5E84_16335	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
N5E84_16340	COG0739	heme binding
N5E84_16350	COG0363	glucosamine-6-phosphate deaminase activity
N5E84_16370	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
N5E84_16375	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N5E84_16395	COG3304	Inner membrane component domain
N5E84_16405	COG2910	NAD(P)H-binding
N5E84_16410	COG0583	DNA-binding transcription factor activity
N5E84_16440	COG0814	amino acid
N5E84_16445	COG2084	Dehydrogenase
N5E84_16485	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
N5E84_16490	COG1444	tRNA N-acetyltransferase activity
N5E84_16500	COG0745	RESPONSE REGULATOR receiver
N5E84_16510	COG0835	chemotaxis
N5E84_16520	COG0840	transmembrane signaling receptor activity
N5E84_16525	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
N5E84_16530	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
N5E84_16555	COG3335	DDE superfamily endonuclease
N5E84_16585	COG0259	pyridoxamine-phosphate oxidase activity
N5E84_16595	COG1262	PFAM Formylglycine-generating sulfatase enzyme
N5E84_16635	COG3335	DDE superfamily endonuclease
N5E84_16665	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N5E84_16670	COG0840	transmembrane signaling receptor activity
N5E84_16690	COG2909	trisaccharide binding
N5E84_16695	COG0058	SHG alpha-glucan phosphorylase activity
N5E84_16700	COG1640	4-alpha-glucanotransferase
N5E84_16705	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
N5E84_16715	COG3501	Rhs element vgr protein
N5E84_16755	COG2433	Pfam Transposase IS66
N5E84_16770	COG1869	D-ribose catabolic process
N5E84_16775	COG1129	ABC transporter
N5E84_16780	COG1172	Belongs to the binding-protein-dependent transport system permease family
N5E84_16785	COG1879	ABC-type sugar transport system periplasmic component
N5E84_16790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N5E84_16795	COG1609	Transcriptional regulator
N5E84_16810	COG0583	DNA-binding transcription factor activity
N5E84_16825	COG0363	glucosamine-6-phosphate deaminase activity
N5E84_16830	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
N5E84_16840	COG1067	ATP-dependent peptidase activity
N5E84_16850	COG2211	Major facilitator Superfamily
N5E84_16885	COG0840	transmembrane signaling receptor activity
N5E84_16895	COG3335	DDE superfamily endonuclease
N5E84_16920	COG3122	Protein conserved in bacteria
N5E84_16925	COG1230	cation diffusion facilitator family transporter
N5E84_16940	COG1881	PFAM PEBP family protein
N5E84_16960	COG1620	l-lactate permease
N5E84_16965	COG0583	DNA-binding transcription factor activity
N5E84_16985	COG3527	Alpha-acetolactate decarboxylase
N5E84_16995	COG0584	glycerophosphoryl diester phosphodiesterase
N5E84_17000	COG2271	Major facilitator Superfamily
N5E84_17040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N5E84_17045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N5E84_17055	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
N5E84_17060	COG0573	inorganic phosphate transmembrane transporter activity
N5E84_17065	COG0581	inorganic phosphate transmembrane transporter activity
N5E84_17070	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N5E84_17090	COG3314	Sporulation integral membrane protein YlbJ
N5E84_17095	COG0659	secondary active sulfate transmembrane transporter activity
N5E84_17105	COG0739	heme binding
N5E84_17110	COG5001	Diguanylate cyclase
N5E84_17115	COG0583	DNA-binding transcription factor activity
N5E84_17120	COG2814	Major facilitator Superfamily
N5E84_17140	COG0697	spore germination
N5E84_17150	COG0179	Fumarylacetoacetate (FAA) hydrolase
N5E84_17170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N5E84_17175	COG0765	amino acid transport
N5E84_17180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N5E84_17185	COG0765	amino acid transport
N5E84_17195	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
N5E84_17205	COG3123	guanosine phosphorylase activity
N5E84_17215	COG1741	Belongs to the pirin family
N5E84_17225	COG5001	Diguanylate cyclase
N5E84_17260	COG3706	GGDEF domain
N5E84_17265	COG3335	DDE superfamily endonuclease
N5E84_17270	COG2315	Protein conserved in bacteria
N5E84_17275	COG0835	chemotaxis
N5E84_17275	COG0784	Response regulator, receiver
N5E84_17280	COG3335	DDE superfamily endonuclease
N5E84_17285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N5E84_17295	COG3842	ATPase activity
N5E84_17305	COG1175	transmembrane transport
N5E84_17310	COG3833	ABC-type maltose transport systems, permease component
N5E84_17335	COG1349	DNA-binding transcription factor activity
N5E84_17340	COG2199	diguanylate cyclase activity
N5E84_17360	COG2354	Protein conserved in bacteria
N5E84_17365	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N5E84_17370	COG0418	dihydroorotase activity
N5E84_17375	COG0633	Ferredoxin
N5E84_17375	COG3217	Mosc domain protein beta barrel domain protein
N5E84_17380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N5E84_17385	COG2195	Cleaves the N-terminal amino acid of tripeptides
N5E84_17400	COG3604	Transcriptional regulator
N5E84_17405	COG1017	nitric oxide dioxygenase activity
N5E84_17405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N5E84_17410	COG4681	YaeQ
N5E84_17415	COG1278	Cold shock
N5E84_17440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N5E84_17445	COG0516	GMP reductase activity
N5E84_17490	COG3501	Rhs element vgr protein
N5E84_17540	COG2204	response regulator
N5E84_17550	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
N5E84_17555	COG0732	type I restriction modification DNA specificity domain
N5E84_17560	COG1196	nuclear chromosome segregation
N5E84_17565	COG3335	DDE superfamily endonuclease
N5E84_17605	COG0714	Associated with various cellular activities
N5E84_17635	COG1132	(ABC) transporter
N5E84_17640	COG1132	(ABC) transporter
N5E84_17645	COG1021	2,3-dihydroxybenzoate-AMP ligase
N5E84_17670	COG2226	methyltransferase
N5E84_17670	COG3433	isochorismatase activity
N5E84_17670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N5E84_17675	COG2814	Major facilitator Superfamily
N5E84_17680	COG4771	TonB-dependent receptor
N5E84_17685	COG4977	sequence-specific DNA binding
N5E84_17685	COG1917	Cupin 2, conserved barrel domain protein
N5E84_17710	COG0589	response to stress
N5E84_17715	COG0659	secondary active sulfate transmembrane transporter activity
N5E84_17720	COG0640	Transcriptional regulator
N5E84_17725	COG0798	PFAM Bile acid sodium symporter
N5E84_17730	COG0640	Transcriptional regulator
N5E84_17735	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N5E84_17760	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
N5E84_17770	COG2271	Major facilitator Superfamily
N5E84_17775	COG3851	Histidine kinase
N5E84_17780	COG2197	response regulator
N5E84_17795	COG0346	lactoylglutathione lyase activity
N5E84_17805	COG0156	8-amino-7-oxononanoate synthase activity
N5E84_17810	COG1063	alcohol dehydrogenase
N5E84_17850	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
N5E84_17860	COG1368	sulfuric ester hydrolase activity
N5E84_17865	COG3530	Putative quorum-sensing-regulated virulence factor
N5E84_17880	COG3706	GGDEF domain
N5E84_17895	COG2304	oxidoreductase activity
N5E84_17915	COG0714	Associated with various cellular activities
N5E84_17935	COG0366	Alpha amylase catalytic
N5E84_17945	COG3335	DDE superfamily endonuclease
N5E84_17975	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
N5E84_17980	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
N5E84_17990	COG0456	acetyltransferase
N5E84_17995	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
N5E84_18000	COG0662	Cupin 2, conserved barrel domain protein
N5E84_18005	COG0527	aspartate kinase activity
N5E84_18010	COG2239	Acts as a magnesium transporter
N5E84_18025	COG2113	Glycine betaine
N5E84_18030	COG3344	reverse transcriptase
N5E84_18035	COG4176	ABC-type proline glycine betaine transport system permease component
N5E84_18050	COG1166	arginine decarboxylase activity
N5E84_18055	COG0010	Belongs to the arginase family
N5E84_18080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N5E84_18105	COG0484	heat shock protein binding
N5E84_18115	COG1716	ATPase activity
N5E84_18115	COG5001	Diguanylate cyclase
N5E84_18120	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
N5E84_18130	COG4181	ATPase activity
N5E84_18135	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
N5E84_18145	COG1984	allophanate hydrolase subunit 2
N5E84_18155	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
N5E84_18160	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N5E84_18170	COG0814	amino acid
N5E84_18175	COG0513	Belongs to the DEAD box helicase family
N5E84_18185	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
N5E84_18200	COG2425	protein containing a von Willebrand factor type A (vWA) domain
N5E84_18225	COG3328	transposase activity
N5E84_18230	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N5E84_18250	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N5E84_18295	COG2433	Pfam Transposase IS66
N5E84_18310	COG0653	protein targeting
N5E84_18320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N5E84_18325	COG0247	lactate metabolic process
N5E84_18330	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
N5E84_18335	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
N5E84_18340	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
N5E84_18345	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
N5E84_18365	COG3132	Protein of unknown function, DUF480
N5E84_18370	COG2827	Endonuclease containing a URI domain
N5E84_18385	COG5002	protein histidine kinase activity
N5E84_18385	COG0784	Response regulator, receiver
N5E84_18415	COG1289	transmembrane transporter activity
N5E84_18420	COG0210	DNA helicase
N5E84_18425	COG1803	Methylglyoxal synthase
N5E84_18430	COG1879	ABC-type sugar transport system periplasmic component
N5E84_18435	COG2205	protein histidine kinase activity
N5E84_18435	COG2198	Histidine kinase
N5E84_18435	COG0784	Response regulator, receiver
N5E84_18440	COG0469	pyruvate kinase activity
N5E84_18445	COG2271	Major facilitator Superfamily
N5E84_18465	COG1979	alcohol dehydrogenase
N5E84_18470	COG2207	Transcriptional regulator
N5E84_18480	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N5E84_18495	COG3111	PFAM Bacterial OB fold (BOF) protein
N5E84_18500	COG1492	cobalamin metabolic process
N5E84_18505	COG0725	ABC transporter, periplasmic molybdate-binding protein
N5E84_18510	COG4149	molybdate abc transporter
N5E84_18515	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
N5E84_18525	COG4251	negative regulation of phosphorylation
N5E84_18525	COG5001	Diguanylate cyclase
N5E84_18525	COG2203	Gaf domain
N5E84_18525	COG3706	GGDEF domain
N5E84_18550	COG5002	protein histidine kinase activity
N5E84_18560	COG2205	protein histidine kinase activity
N5E84_18565	COG3300	MHYT domain
N5E84_18565	COG5001	Diguanylate cyclase
N5E84_18590	COG2433	Pfam Transposase IS66
N5E84_18600	COG2433	Pfam Transposase IS66
N5E84_18615	COG3041	Addiction module toxin RelE StbE family
N5E84_18630	COG0724	RNA recognition motif
N5E84_18670	COG2433	Pfam Transposase IS66
N5E84_18690	COG3335	DDE superfamily endonuclease
N5E84_18770	COG0023	Translation Initiation Factor
N5E84_18785	COG1181	Belongs to the D-alanine--D-alanine ligase family
N5E84_18795	COG0045	succinate-CoA ligase (ADP-forming) activity
N5E84_18795	COG1042	CoA-binding domain protein
N5E84_18795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N5E84_18800	COG0583	DNA-binding transcription factor activity
N5E84_18830	COG2433	Pfam Transposase IS66
N5E84_18865	COG2433	Pfam Transposase IS66
N5E84_18890	COG3140	Belongs to the UPF0181 family
N5E84_18905	COG0745	RESPONSE REGULATOR receiver
N5E84_18915	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
N5E84_18920	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
N5E84_18940	COG3335	DDE superfamily endonuclease
N5E84_18950	COG1278	Cold shock
N5E84_18960	COG0840	transmembrane signaling receptor activity
N5E84_18975	COG3328	transposase activity
N5E84_18980	COG2501	S4 domain
N5E84_18985	COG0625	glutathione transferase activity
N5E84_19005	COG0488	(ABC) transporter
N5E84_19020	COG2050	protein possibly involved in aromatic compounds catabolism
N5E84_19030	COG2824	Alkylphosphonate utilization operon protein PhnA
N5E84_19045	COG0861	Integral membrane protein TerC family
N5E84_19050	COG0737	Belongs to the 5'-nucleotidase family
N5E84_19055	COG3593	DNA synthesis involved in DNA repair
N5E84_19065	COG0583	DNA-binding transcription factor activity
N5E84_19070	COG2116	formate transmembrane transporter activity
N5E84_19080	COG3104	oligopeptide transport
N5E84_19090	COG2188	Transcriptional regulator
N5E84_19095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N5E84_19100	COG1011	Hydrolase
N5E84_19105	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
N5E84_19110	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
N5E84_19115	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N5E84_19125	COG2759	Belongs to the formate--tetrahydrofolate ligase family
N5E84_19130	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N5E84_19130	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N5E84_19135	COG0302	gtp cyclohydrolase
N5E84_19140	COG0303	'Molybdopterin
N5E84_19145	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N5E84_19150	COG2897	thiosulfate sulfurtransferase activity
N5E84_19170	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
N5E84_19185	COG0545	Peptidyl-prolyl cis-trans isomerase
N5E84_19190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N5E84_19195	COG3335	DDE superfamily endonuclease
N5E84_19200	COG0840	transmembrane signaling receptor activity
N5E84_19205	COG2353	YceI-like domain
N5E84_19210	COG3038	cytochrome b561
N5E84_19225	COG2203	Gaf domain
N5E84_19225	COG3706	GGDEF domain
N5E84_19225	COG4251	negative regulation of phosphorylation
N5E84_19225	COG5001	Diguanylate cyclase
N5E84_19230	COG4172	Belongs to the ABC transporter superfamily
N5E84_19235	COG4239	(ABC) transporter, permease
N5E84_19240	COG4174	ABC transporter (Permease)
N5E84_19245	COG4166	transmembrane transport
N5E84_19255	COG4067	protein conserved in archaea
N5E84_19255	COG0189	ligase activity
N5E84_19300	COG3040	lipid binding
N5E84_19335	COG2433	Pfam Transposase IS66
N5E84_19390	COG3335	DDE superfamily endonuclease
N5E84_19440	COG2433	Pfam Transposase IS66
N5E84_19470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N5E84_19490	COG2433	Pfam Transposase IS66
N5E84_19510	COG1328	CTP reductase activity
N5E84_19515	COG1328	CTP reductase activity
N5E84_19520	COG0602	queuosine metabolic process
N5E84_19550	COG2433	Pfam Transposase IS66
N5E84_19565	COG2433	Pfam Transposase IS66
N5E84_19615	COG4115	mRNA cleavage
N5E84_19620	COG2161	toxin-antitoxin pair type II binding
N5E84_19625	COG2433	Pfam Transposase IS66
N5E84_19660	COG0346	lactoylglutathione lyase activity
N5E84_19670	COG3093	addiction module antidote protein HigA
N5E84_19675	COG3549	Plasmid maintenance system killer
N5E84_19745	COG2433	Pfam Transposase IS66
N5E84_19815	COG0242	peptide deformylase activity
N5E84_19850	COG2433	Pfam Transposase IS66
N5E84_19985	COG2433	Pfam Transposase IS66
N5E84_20040	COG4682	membrane
N5E84_20070	COG2801	Transposase and inactivated derivatives
N5E84_20115	COG0513	Belongs to the DEAD box helicase family
N5E84_20120	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
N5E84_20130	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
N5E84_20155	COG3069	C4-dicarboxylate transmembrane transporter activity
N5E84_20160	COG2197	response regulator
N5E84_20165	COG3850	Histidine kinase
N5E84_20170	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
N5E84_20180	COG0243	molybdopterin cofactor binding
N5E84_20190	COG3005	denitrification pathway
N5E84_20200	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N5E84_20205	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N5E84_20230	COG3730	PTS system glucitol sorbitol-specific
N5E84_20235	COG1349	DNA-binding transcription factor activity
N5E84_20240	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
N5E84_20245	COG1028	Short-chain dehydrogenase reductase Sdr
N5E84_20260	COG3730	PTS system glucitol sorbitol-specific
N5E84_20300	COG3335	DDE superfamily endonuclease
N5E84_20310	COG3675	Pfam Lipase (class 3)
N5E84_20320	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
N5E84_20335	COG1136	(ABC) transporter
N5E84_20335	COG0577	efflux transmembrane transporter activity
N5E84_20345	COG1136	(ABC) transporter
N5E84_20350	COG0523	cobalamin synthesis protein
N5E84_20355	COG0038	chloride channel
N5E84_20365	COG0156	8-amino-7-oxononanoate synthase activity
N5E84_20370	COG2205	protein histidine kinase activity
N5E84_20370	COG0784	Response regulator, receiver
N5E84_20375	COG0419	ATPase involved in DNA repair
N5E84_20380	COG0420	3'-5' exonuclease activity
N5E84_20385	COG1609	Transcriptional regulator
N5E84_20390	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N5E84_20390	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
N5E84_20395	COG1105	Belongs to the carbohydrate kinase PfkB family
N5E84_20400	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N5E84_20400	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N5E84_20400	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
N5E84_20440	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
N5E84_20445	COG0509	glycine decarboxylation via glycine cleavage system
N5E84_20470	COG0697	spore germination
N5E84_20485	COG0861	Integral membrane protein TerC family
N5E84_20510	COG2814	Major facilitator Superfamily
N5E84_20520	COG3344	reverse transcriptase
N5E84_20525	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
N5E84_20530	COG4604	ABC transporter, ATP-binding protein
N5E84_20535	COG4605	iron ion homeostasis
N5E84_20540	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N5E84_20545	COG4607	ABC-type enterochelin transport system periplasmic component
N5E84_20575	COG5380	lipid catabolic process
N5E84_20580	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
N5E84_20590	COG3240	lipase activity
N5E84_20635	COG4191	Histidine kinase
N5E84_20635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N5E84_20645	COG3437	response regulator, receiver
N5E84_20645	COG0784	Response regulator, receiver
N5E84_20650	COG2207	Transcriptional regulator
N5E84_20655	COG0534	Mate efflux family protein
N5E84_20660	COG0840	transmembrane signaling receptor activity
N5E84_20665	COG2154	pterin-4-alpha-carbinolamine dehydratase
N5E84_20670	COG3186	Phenylalanine-4-hydroxylase
N5E84_20675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N5E84_20680	COG0583	DNA-binding transcription factor activity
N5E84_20690	COG0583	DNA-binding transcription factor activity
N5E84_20705	COG0110	maltose O-acetyltransferase activity
N5E84_20710	COG1765	OsmC-like protein
N5E84_20715	COG0673	inositol 2-dehydrogenase activity
N5E84_20735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N5E84_20740	COG1609	Transcriptional regulator
N5E84_20750	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N5E84_20770	COG0745	RESPONSE REGULATOR receiver
N5E84_20800	COG0531	amino acid
N5E84_20810	COG3437	response regulator, receiver
N5E84_20810	COG2205	protein histidine kinase activity
N5E84_20810	COG3850	Histidine kinase
N5E84_20810	COG4999	Histidine kinase
N5E84_20815	COG3437	response regulator, receiver
N5E84_20825	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
N5E84_20835	COG5001	Diguanylate cyclase
N5E84_20835	COG4251	negative regulation of phosphorylation
N5E84_20835	COG2203	Gaf domain
N5E84_20835	COG3706	GGDEF domain
N5E84_20840	COG3279	Response regulator of the LytR AlgR family
N5E84_20845	COG0745	RESPONSE REGULATOR receiver
N5E84_20845	COG2972	Histidine kinase
N5E84_20860	COG0577	efflux transmembrane transporter activity
N5E84_20860	COG1136	(ABC) transporter
N5E84_20865	COG0577	efflux transmembrane transporter activity
N5E84_20865	COG1136	(ABC) transporter
N5E84_20875	COG4989	oxidoreductase activity
N5E84_20880	COG0366	Alpha amylase catalytic
N5E84_20890	COG2267	carboxylic ester hydrolase activity
N5E84_20925	COG0513	Belongs to the DEAD box helicase family
N5E84_20935	COG1376	ErfK ybiS ycfS ynhG family protein
N5E84_20935	COG1388	LysM domain
N5E84_20940	COG0415	Belongs to the DNA photolyase family
N5E84_20945	COG0789	Transcriptional regulator
N5E84_20950	COG3272	Protein of unknown function (DUF1722)
N5E84_20955	COG0813	purine-nucleoside phosphorylase activity
N5E84_20980	COG1566	PFAM secretion protein HlyD family protein
N5E84_21010	COG0786	glutamate:sodium symporter activity
N5E84_21025	COG1999	signal sequence binding
N5E84_21035	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
N5E84_21045	COG0366	Alpha amylase catalytic
N5E84_21060	COG3335	DDE superfamily endonuclease