locus-tag	class	description
J4N43_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J4N43_00010	COG0592	DNA-directed DNA polymerase activity
J4N43_00020	COG0187	DNA topoisomerase II activity
J4N43_00030	COG0071	Belongs to the small heat shock protein (HSP20) family
J4N43_00035	COG3977	Valine--pyruvate aminotransferase
J4N43_00040	COG0366	Alpha amylase catalytic
J4N43_00055	COG2119	membrane
J4N43_00065	COG0425	Belongs to the sulfur carrier protein TusA family
J4N43_00080	COG0604	alcohol dehydrogenase
J4N43_00085	COG0183	Belongs to the thiolase family
J4N43_00100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4N43_00150	COG2132	Multicopper oxidase
J4N43_00170	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J4N43_00175	COG2104	thiamine diphosphate biosynthetic process
J4N43_00190	COG0006	proline dipeptidase activity
J4N43_00190	COG0006	proline dipeptidase activity
J4N43_00220	COG3220	belongs to the UPF0276 family
J4N43_00230	COG0210	DNA helicase
J4N43_00240	COG0405	Gamma-glutamyltransferase
J4N43_00245	COG1280	lysine exporter protein (LysE YggA)
J4N43_00255	COG2962	Rard protein
J4N43_00260	COG0514	ATP-dependent DNA helicase (RecQ)
J4N43_00270	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J4N43_00280	COG0248	Ppx GppA phosphatase
J4N43_00285	COG0513	Belongs to the DEAD box helicase family
J4N43_00290	COG3118	belongs to the thioredoxin family
J4N43_00305	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
J4N43_00310	COG0633	Ferredoxin
J4N43_00355	COG3071	HemY protein
J4N43_00360	COG2959	enzyme of heme biosynthesis
J4N43_00365	COG1587	Uroporphyrinogen-III synthase
J4N43_00370	COG0181	hydroxymethylbilane synthase activity
J4N43_00375	COG3072	Adenylate cyclase
J4N43_00380	COG1965	Belongs to the frataxin family
J4N43_00390	COG0019	diaminopimelate decarboxylase activity
J4N43_00405	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J4N43_00410	COG1011	Hydrolase
J4N43_00415	COG2199	diguanylate cyclase activity
J4N43_00415	COG2200	EAL domain
J4N43_00415	COG3287	FIST C domain
J4N43_00420	COG3148	PFAM DTW domain containing protein
J4N43_00435	COG0561	phosphatase activity
J4N43_00440	COG2267	carboxylic ester hydrolase activity
J4N43_00445	COG1280	lysine exporter protein (LysE YggA)
J4N43_00450	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J4N43_00455	COG0640	Transcriptional regulator
J4N43_00460	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J4N43_00500	COG2095	MarC family integral membrane protein
J4N43_00510	COG0742	ribosomal rna small subunit methyltransferase
J4N43_00515	COG0552	protein localization to endoplasmic reticulum
J4N43_00520	COG2884	Cell division ATP-binding protein ftsE
J4N43_00525	COG2177	Part of the ABC transporter FtsEX involved in
J4N43_00535	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4N43_00540	COG0705	Rhomboid family
J4N43_00545	COG1580	Controls the rotational direction of flagella during chemotaxis
J4N43_00550	COG3161	chorismate lyase activity
J4N43_00555	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
J4N43_00560	COG2937	Belongs to the GPAT DAPAT family
J4N43_00565	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J4N43_00570	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
J4N43_00575	COG0534	Mate efflux family protein
J4N43_00580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N43_00600	COG4206	TonB-dependent receptor
J4N43_00680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4N43_00690	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J4N43_00695	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
J4N43_00695	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
J4N43_00725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J4N43_00730	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J4N43_00735	COG0250	Participates in transcription elongation, termination and antitermination
J4N43_00750	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J4N43_00755	COG0222	ribosome binding
J4N43_00760	COG0085	RNA polymerase activity
J4N43_00765	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J4N43_00770	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
J4N43_00775	COG2816	NAD+ diphosphatase activity
J4N43_00780	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
J4N43_00785	COG1573	uracil-dna glycosylase
J4N43_00795	COG3068	Protein conserved in bacteria
J4N43_00800	COG1253	flavin adenine dinucleotide binding
J4N43_00815	COG0151	Belongs to the GarS family
J4N43_00825	COG0789	Transcriptional regulator
J4N43_00830	COG3710	Transcriptional regulator
J4N43_00835	COG0531	amino acid
J4N43_00840	COG1982	Orn Lys Arg decarboxylase major
J4N43_00890	COG0488	(ABC) transporter
J4N43_00900	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
J4N43_00905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4N43_00910	COG2264	protein methyltransferase activity
J4N43_00915	COG0439	Biotin carboxylase
J4N43_00920	COG0511	ligase activity, forming carbon-carbon bonds
J4N43_00925	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J4N43_00930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J4N43_00945	COG2814	Major facilitator Superfamily
J4N43_00970	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N43_00980	COG3263	regulation of cellular component size
J4N43_00990	COG4232	protein-disulfide reductase activity
J4N43_00995	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J4N43_01000	COG1027	Aspartate ammonia-lyase
J4N43_01005	COG3030	protein affecting phage T7 exclusion by the F plasmid
J4N43_01010	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J4N43_01020	COG2205	protein histidine kinase activity
J4N43_01025	COG0745	RESPONSE REGULATOR receiver
J4N43_01030	COG3678	ATP-independent chaperone mediated protein folding
J4N43_01035	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J4N43_01040	COG0205	6-phosphofructokinase activity
J4N43_01045	COG0534	Mate efflux family protein
J4N43_01055	COG0459	protein refolding
J4N43_01065	COG1285	pathogenesis
J4N43_01070	COG1509	lysine 2,3-aminomutase activity
J4N43_01085	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
J4N43_01090	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
J4N43_01095	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J4N43_01100	COG1053	succinate dehydrogenase
J4N43_01105	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
J4N43_01125	COG4942	peptidase
J4N43_01130	COG1045	serine acetyltransferase
J4N43_01135	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J4N43_01140	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
J4N43_01145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4N43_01150	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J4N43_01160	COG3273	potassium ion transport
J4N43_01160	COG0471	metal ion transport
J4N43_01165	COG0688	phosphatidylethanolamine metabolic process
J4N43_01170	COG1162	GTPase activity
J4N43_01175	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
J4N43_01240	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J4N43_01245	COG0802	atpase or kinase
J4N43_01255	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J4N43_01260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J4N43_01270	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J4N43_01275	COG0330	HflC and HflK could
J4N43_01280	COG0330	HflC and HflK could
J4N43_01285	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
J4N43_01290	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J4N43_01295	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
J4N43_01300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4N43_01300	COG1017	nitric oxide dioxygenase activity
J4N43_01305	COG1959	2 iron, 2 sulfur cluster binding
J4N43_01310	COG0557	exoribonuclease II activity
J4N43_01315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4N43_01320	COG0546	phosphoglycolate phosphatase activity
J4N43_01325	COG0180	Tryptophanyl-tRNA synthetase
J4N43_01340	COG0583	DNA-binding transcription factor activity
J4N43_01345	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J4N43_01350	COG1473	amidohydrolase
J4N43_01360	COG0697	spore germination
J4N43_01370	COG0512	Glutamine amidotransferase of anthranilate synthase
J4N43_01375	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J4N43_01395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N43_01400	COG3954	Phosphoribulokinase
J4N43_01410	COG0429	hydrolase of the alpha beta-hydrolase fold
J4N43_01420	COG0488	(ABC) transporter
J4N43_01425	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N43_01440	COG1047	Peptidyl-prolyl cis-trans
J4N43_01445	COG1446	asparaginase
J4N43_01460	COG0545	Peptidyl-prolyl cis-trans isomerase
J4N43_01465	COG2964	Protein conserved in bacteria
J4N43_01470	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
J4N43_01475	COG2923	Belongs to the DsrF TusC family
J4N43_01495	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J4N43_01500	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J4N43_01515	COG0281	malic enzyme
J4N43_01520	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
J4N43_01525	COG0626	cystathionine gamma-synthase activity
J4N43_01530	COG0460	homoserine dehydrogenase
J4N43_01530	COG0527	aspartate kinase activity
J4N43_01535	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J4N43_01545	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
J4N43_01555	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J4N43_01565	COG0137	argininosuccinate synthase activity
J4N43_01580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N43_01585	COG0678	peroxiredoxin activity
J4N43_01585	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J4N43_01595	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J4N43_01625	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J4N43_01630	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J4N43_01640	COG0338	D12 class N6 adenine-specific DNA methyltransferase
J4N43_01645	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J4N43_01650	COG0360	Binds together with S18 to 16S ribosomal RNA
J4N43_01655	COG2965	DNA replication, synthesis of RNA primer
J4N43_01680	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J4N43_01685	COG0432	Pfam Uncharacterised protein family UPF0047
J4N43_01690	COG0166	Belongs to the GPI family
J4N43_01700	COG0735	belongs to the Fur family
J4N43_01705	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4N43_01725	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J4N43_01730	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4N43_01735	COG0175	sulfate reduction
J4N43_01795	COG0646	methionine synthase
J4N43_01795	COG1410	methionine synthase
J4N43_01800	COG0527	aspartate kinase activity
J4N43_01805	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J4N43_01815	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J4N43_01830	COG0629	single-stranded DNA binding
J4N43_01835	COG2200	EAL domain
J4N43_01835	COG2199	diguanylate cyclase activity
J4N43_01855	COG1450	Type ii and iii secretion system protein
J4N43_01860	COG3409	Peptidoglycan-binding domain 1 protein
J4N43_01860	COG3267	Type II secretory pathway component ExeA
J4N43_01870	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4N43_01875	COG1459	type II secretion system
J4N43_01885	COG2165	general secretion pathway protein
J4N43_01915	COG1077	Cell shape determining protein MreB Mrl
J4N43_01920	COG1792	Involved in formation and maintenance of cell shape
J4N43_01925	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
J4N43_01930	COG0424	maF-like protein
J4N43_01940	COG3164	Protein of unknown function
J4N43_01945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J4N43_01950	COG0312	modulator of DNA gyrase
J4N43_01955	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J4N43_01960	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J4N43_01970	COG0564	pseudouridine synthase activity
J4N43_01975	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J4N43_01980	COG3028	Belongs to the UPF0307 family
J4N43_01985	COG0312	modulator of DNA gyrase
J4N43_01990	COG2239	Acts as a magnesium transporter
J4N43_01995	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N43_02000	COG1660	Displays ATPase and GTPase activities
J4N43_02005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N43_02010	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J4N43_02020	COG1137	ATPase activity
J4N43_02025	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J4N43_02035	COG0517	IMP dehydrogenase activity
J4N43_02035	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J4N43_02045	COG1127	ABC transporter
J4N43_02050	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J4N43_02055	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J4N43_02060	COG2854	intermembrane phospholipid transfer
J4N43_02070	COG5007	Belongs to the BolA IbaG family
J4N43_02075	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J4N43_02080	COG0204	Acyl-transferase
J4N43_02085	COG0251	oxidation-reduction process
J4N43_02090	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
J4N43_02095	COG0540	Belongs to the ATCase OTCase family
J4N43_02125	COG0456	acetyltransferase
J4N43_02140	COG2927	DNA polymerase III (CHI subunit)
J4N43_02145	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J4N43_02150	COG0795	lipopolysaccharide-transporting ATPase activity
J4N43_02155	COG0795	lipopolysaccharide-transporting ATPase activity
J4N43_02170	COG1028	Short-chain dehydrogenase reductase Sdr
J4N43_02180	COG0726	polysaccharide deacetylase
J4N43_02185	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4N43_02190	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4N43_02195	COG1447	Phosphotransferase system cellobiose-specific component IIA
J4N43_02200	COG1486	melibiose metabolic process
J4N43_02205	COG3394	polysaccharide catabolic process
J4N43_02210	COG1609	Transcriptional regulator
J4N43_02215	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J4N43_02290	COG0840	transmembrane signaling receptor activity
J4N43_02335	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
J4N43_02345	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J4N43_02355	COG2066	Belongs to the glutaminase family
J4N43_02360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J4N43_02365	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J4N43_02375	COG1872	DUF167
J4N43_02380	COG0762	integral membrane protein
J4N43_02385	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J4N43_02390	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J4N43_02405	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J4N43_02410	COG1678	Uncharacterized ACR, COG1678
J4N43_02415	COG0189	ligase activity
J4N43_02420	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J4N43_02425	COG2356	endonuclease I
J4N43_02440	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J4N43_02445	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J4N43_02450	COG0583	DNA-binding transcription factor activity
J4N43_02455	COG4771	TonB-dependent receptor
J4N43_02460	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J4N43_02470	COG0191	fructose-bisphosphate aldolase activity
J4N43_02475	COG0668	transmembrane transport
J4N43_02490	COG0583	DNA-binding transcription factor activity
J4N43_02500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4N43_02505	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
J4N43_02510	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J4N43_02520	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
J4N43_02525	COG3079	Belongs to the UPF0149 family
J4N43_02530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N43_02535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N43_02555	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J4N43_02565	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J4N43_02570	COG1595	DNA-templated transcription, initiation
J4N43_02585	COG3086	response to oxidative stress
J4N43_02590	COG0481	GTPase activity
J4N43_02595	COG0681	Belongs to the peptidase S26 family
J4N43_02605	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J4N43_02610	COG1381	Involved in DNA repair and RecF pathway recombination
J4N43_02615	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J4N43_02620	COG0736	holo-[acyl-carrier-protein] synthase activity
J4N43_02630	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J4N43_02635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J4N43_02640	COG3956	TIGRFAM MazG family protein
J4N43_02645	COG0504	CTP synthase activity
J4N43_02650	COG0148	phosphopyruvate hydratase activity
J4N43_02655	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J4N43_02660	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J4N43_02665	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J4N43_02675	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J4N43_02680	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J4N43_02690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J4N43_02695	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J4N43_02700	COG1546	Belongs to the CinA family
J4N43_02705	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J4N43_02710	COG2137	regulation of response to DNA damage stimulus
J4N43_02715	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J4N43_02720	COG0527	aspartate kinase activity
J4N43_02780	COG3630	sodium ion export across plasma membrane
J4N43_02785	COG0511	ligase activity, forming carbon-carbon bonds
J4N43_02785	COG5016	pyruvate
J4N43_02790	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
J4N43_02800	COG1238	metal cluster binding
J4N43_02805	COG0612	Peptidase, M16
J4N43_02810	COG2918	glutathione biosynthetic process
J4N43_02820	COG1854	S-ribosylhomocysteine lyase activity
J4N43_02825	COG4536	flavin adenine dinucleotide binding
J4N43_02835	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J4N43_02840	COG0228	four-way junction DNA binding
J4N43_02845	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J4N43_02860	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
J4N43_02865	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
J4N43_02870	COG0237	dephospho-CoA kinase activity
J4N43_02880	COG1459	type II secretion system
J4N43_02885	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4N43_02895	COG0157	Belongs to the NadC ModD family
J4N43_02905	COG2186	Transcriptional regulator
J4N43_02910	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
J4N43_02915	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4N43_02920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N43_02935	COG0288	reversible hydration of carbon dioxide
J4N43_02940	COG0659	secondary active sulfate transmembrane transporter activity
J4N43_02945	COG1131	(ABC) transporter
J4N43_02950	COG0842	Transport permease protein
J4N43_02955	COG1560	Kdo2-lipid A biosynthetic process
J4N43_02960	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
J4N43_02965	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J4N43_02970	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J4N43_02980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J4N43_02990	COG1489	DNA binding
J4N43_02995	COG1643	Atp-dependent helicase
J4N43_03000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4N43_03005	COG1752	Esterase of the alpha-beta hydrolase superfamily
J4N43_03010	COG1049	propionate catabolic process, 2-methylcitrate cycle
J4N43_03015	COG3112	Uncharacterised protein family (UPF0231)
J4N43_03025	COG0004	ammonium transporteR
J4N43_03030	COG1840	ABC-type Fe3 transport system, periplasmic component
J4N43_03040	COG3842	ATPase activity
J4N43_03045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4N43_03060	COG2971	BadF BadG BcrA BcrD
J4N43_03070	COG4608	Belongs to the ABC transporter superfamily
J4N43_03075	COG0444	Belongs to the ABC transporter superfamily
J4N43_03080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N43_03090	COG0747	negative chemotaxis
J4N43_03095	COG0784	Response regulator, receiver
J4N43_03095	COG2205	protein histidine kinase activity
J4N43_03105	COG0628	permease
J4N43_03130	COG0739	heme binding
J4N43_03135	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J4N43_03145	COG2027	D-alanyl-D-alanine carboxypeptidase
J4N43_03150	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J4N43_03155	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4N43_03160	COG1534	Rna-binding protein
J4N43_03165	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
J4N43_03170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J4N43_03175	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J4N43_03180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4N43_03185	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J4N43_03200	COG0779	Required for maturation of 30S ribosomal subunits
J4N43_03205	COG0195	Participates in both transcription termination and antitermination
J4N43_03210	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J4N43_03215	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J4N43_03220	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J4N43_03225	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J4N43_03230	COG1185	polyribonucleotide nucleotidyltransferase activity
J4N43_03245	COG0534	Mate efflux family protein
J4N43_03250	COG0826	peptidase U32
J4N43_03255	COG0826	peptidase U32
J4N43_03265	COG3154	lipid carrier protein
J4N43_03270	COG3153	acetyltransferase
J4N43_03300	COG0084	hydrolase, TatD family'
J4N43_03305	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4N43_03310	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
J4N43_03315	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
J4N43_03320	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
J4N43_03325	COG0813	purine-nucleoside phosphorylase activity
J4N43_03335	COG0560	Phosphoserine phosphatase
J4N43_03345	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J4N43_03350	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J4N43_03355	COG0583	DNA-binding transcription factor activity
J4N43_03365	COG1022	Amp-dependent synthetase and ligase
J4N43_03405	COG0583	DNA-binding transcription factor activity
J4N43_03410	COG1609	Transcriptional regulator
J4N43_03430	COG0598	Magnesium transport protein CorA
J4N43_03435	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J4N43_03440	COG1349	DNA-binding transcription factor activity
J4N43_03445	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J4N43_03450	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J4N43_03455	COG2271	Major facilitator Superfamily
J4N43_03460	COG0584	glycerophosphoryl diester phosphodiesterase
J4N43_03465	COG2171	N-acyltransferase activity
J4N43_03480	COG3141	response to X-ray
J4N43_03500	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J4N43_03505	COG1074	ATP-dependent DNA helicase activity
J4N43_03510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J4N43_03520	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J4N43_03520	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J4N43_03530	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
J4N43_03535	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J4N43_03540	COG2166	iron-sulfur cluster assembly
J4N43_03545	COG3706	GGDEF domain
J4N43_03550	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J4N43_03555	COG0693	protein deglycase activity
J4N43_03560	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J4N43_03565	COG3248	Nucleoside-binding outer membrane protein
J4N43_03580	COG1595	DNA-templated transcription, initiation
J4N43_03600	COG3056	Lipoprotein
J4N43_03605	COG2813	Specifically methylates the guanine in position
J4N43_03610	COG0271	Belongs to the BolA IbaG family
J4N43_03615	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J4N43_03620	COG1805	sodium ion transport
J4N43_03625	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J4N43_03630	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J4N43_03635	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J4N43_03640	COG2871	sodium ion transport
J4N43_03645	COG1477	protein flavinylation
J4N43_03665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J4N43_03670	COG0514	ATP-dependent DNA helicase (RecQ)
J4N43_03690	COG0733	neurotransmitter:sodium symporter activity
J4N43_03710	COG0442	prolyl-tRNA aminoacylation
J4N43_03715	COG1720	tRNA m6t6A37 methyltransferase activity
J4N43_03720	COG0254	rRNA binding
J4N43_03730	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J4N43_03755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4N43_03790	COG3098	single-species biofilm formation
J4N43_03795	COG0564	pseudouridine synthase activity
J4N43_03805	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
J4N43_03810	COG0024	Methionine aminopeptidase
J4N43_03815	COG0052	Belongs to the universal ribosomal protein uS2 family
J4N43_03820	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J4N43_03825	COG0528	UMP kinase activity
J4N43_03830	COG0233	cytoplasmic translational termination
J4N43_03835	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J4N43_03840	COG0575	Belongs to the CDS family
J4N43_03845	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J4N43_03850	COG0750	zinc metalloprotease
J4N43_03860	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
J4N43_03865	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4N43_03875	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4N43_03880	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4N43_03890	COG0587	DNA-directed DNA polymerase activity
J4N43_03895	COG0825	malonyl-CoA metabolic process
J4N43_03910	COG0347	Belongs to the P(II) protein family
J4N43_03915	COG3021	interspecies interaction between organisms
J4N43_03930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4N43_03935	COG2226	methyltransferase
J4N43_03940	COG0328	RNA-DNA hybrid ribonuclease activity
J4N43_03980	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J4N43_03985	COG0121	glutamine amidotransferase
J4N43_03990	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J4N43_03995	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J4N43_04000	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J4N43_04005	COG2233	PERMEase
J4N43_04025	COG1393	Belongs to the ArsC family
J4N43_04030	COG4783	chaperone-mediated protein folding
J4N43_04045	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J4N43_04055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J4N43_04060	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
J4N43_04075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J4N43_04080	COG1393	Belongs to the ArsC family
J4N43_04105	COG2837	iron assimilation
J4N43_04110	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N43_04115	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N43_04120	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N43_04125	COG1334	flagellar protein FlaG
J4N43_04130	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J4N43_04140	COG1516	flagellar protein fliS
J4N43_04160	COG1677	Flagellar hook-basal body complex protein FliE
J4N43_04170	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J4N43_04230	COG1987	bacterial-type flagellum assembly
J4N43_04235	COG1684	flagellar biosynthetic protein fliR
J4N43_04270	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
J4N43_04275	COG0643	Histidine kinase
J4N43_04275	COG0784	Response regulator, receiver
J4N43_04275	COG2198	Histidine kinase
J4N43_04280	COG2201	protein-glutamate methylesterase activity
J4N43_04285	COG1192	Involved in chromosome partitioning
J4N43_04295	COG0835	chemotaxis
J4N43_04305	COG4133	protoheme IX ABC transporter activity
J4N43_04310	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4N43_04315	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4N43_04320	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4N43_04325	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
J4N43_04330	COG1138	Cytochrome C-type biogenesis protein
J4N43_04335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4N43_04345	COG4235	cytochrome complex assembly
J4N43_04345	COG3088	subunit of a heme lyase
J4N43_04355	COG2067	long-chain fatty acid transport protein
J4N43_04375	COG0183	Belongs to the thiolase family
J4N43_04380	COG1250	3-hydroxyacyl-CoA dehydrogenase
J4N43_04380	COG1024	Enoyl-CoA hydratase
J4N43_04395	COG2062	phosphohistidine phosphatase, SixA
J4N43_04400	COG2840	Smr protein MutS2
J4N43_04405	COG2890	protein-(glutamine-N5) methyltransferase activity
J4N43_04410	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J4N43_04415	COG2860	membrane
J4N43_04420	COG3101	peptidyl-lysine hydroxylation
J4N43_04430	COG0431	NADPH-dependent FMN reductase
J4N43_04435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4N43_04435	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
J4N43_04440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J4N43_04445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4N43_04450	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J4N43_04460	COG0101	tRNA pseudouridine synthase activity
J4N43_04465	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J4N43_04470	COG0285	dihydrofolate synthase activity
J4N43_04475	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
J4N43_04480	COG1286	toxin biosynthetic process
J4N43_04485	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J4N43_04490	COG0583	DNA-binding transcription factor activity
J4N43_04495	COG0745	RESPONSE REGULATOR receiver
J4N43_04500	COG2832	Protein of unknown function (DUF454)
J4N43_04505	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J4N43_04520	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J4N43_04525	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J4N43_04535	COG2261	transglycosylase associated protein
J4N43_04595	COG0668	transmembrane transport
J4N43_04600	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
J4N43_04605	COG0346	lactoylglutathione lyase activity
J4N43_04615	COG1785	Belongs to the alkaline phosphatase family
J4N43_04630	COG2226	methyltransferase
J4N43_04645	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J4N43_04650	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N43_04660	COG3139	Protein of unknown function (DUF1315)
J4N43_04665	COG0252	asparaginase activity
J4N43_04670	COG0616	signal peptide processing
J4N43_04675	COG0446	pyridine nucleotide-disulphide oxidoreductase
J4N43_04675	COG1902	pentaerythritol trinitrate reductase activity
J4N43_04685	COG0778	Nitroreductase
J4N43_04690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4N43_04705	COG0123	including yeast histone deacetylase and acetoin utilization protein
J4N43_04720	COG3082	Protein of unknown function (DUF1414)
J4N43_04725	COG3081	Nucleoid-associated protein
J4N43_04740	COG1757	Na H antiporter
J4N43_04745	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J4N43_04750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N43_04755	COG2095	MarC family integral membrane protein
J4N43_04760	COG1454	alcohol dehydrogenase
J4N43_04760	COG1012	belongs to the aldehyde dehydrogenase family
J4N43_04780	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J4N43_04800	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J4N43_04910	COG4695	Portal protein
J4N43_05040	COG2056	Na+-H+ antiporter family
J4N43_05045	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J4N43_05050	COG2885	chlorophyll binding
J4N43_05060	COG0346	lactoylglutathione lyase activity
J4N43_05065	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J4N43_05070	COG4660	Part of a membrane complex involved in electron transport
J4N43_05075	COG4659	FMN binding
J4N43_05080	COG4658	electron transport chain
J4N43_05085	COG4656	Part of a membrane complex involved in electron transport
J4N43_05090	COG2878	Part of a membrane complex involved in electron transport
J4N43_05095	COG4657	Part of a membrane complex involved in electron transport
J4N43_05100	COG1882	Formate acetyltransferase
J4N43_05110	COG0556	nucleotide-excision repair
J4N43_05115	COG2204	response regulator
J4N43_05120	COG2198	Histidine kinase
J4N43_05125	COG0391	Required for morphogenesis under gluconeogenic growth conditions
J4N43_05130	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J4N43_05135	COG0521	Mo-molybdopterin cofactor biosynthetic process
J4N43_05140	COG0315	cyclic pyranopterin monophosphate synthase activity
J4N43_05145	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J4N43_05150	COG0314	molybdopterin synthase activity
J4N43_05160	COG0601	transmembrane transport
J4N43_05165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N43_05170	COG0444	Belongs to the ABC transporter superfamily
J4N43_05180	COG0435	Glutathione S-transferase
J4N43_05190	COG0280	phosphate acetyltransferase
J4N43_05190	COG0857	belongs to the CobB CobQ family
J4N43_05195	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J4N43_05200	COG3092	negative regulation of chromosome organization
J4N43_05210	COG4120	Belongs to the binding-protein-dependent transport system permease family
J4N43_05215	COG1122	ATPase activity
J4N43_05220	COG0366	Alpha amylase catalytic
J4N43_05225	COG3706	GGDEF domain
J4N43_05230	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4N43_05235	COG3012	SEC-C Motif Domain Protein
J4N43_05235	COG3318	Belongs to the UPF0149 family
J4N43_05240	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
J4N43_05245	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J4N43_05250	COG2186	Transcriptional regulator
J4N43_05275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4N43_05275	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4N43_05285	COG0572	uridine kinase
J4N43_05295	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
J4N43_05300	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J4N43_05305	COG0659	secondary active sulfate transmembrane transporter activity
J4N43_05310	COG1530	ribonuclease E activity
J4N43_05315	COG0564	pseudouridine synthase activity
J4N43_05320	COG0424	maF-like protein
J4N43_05325	COG1399	metal-binding, possibly nucleic acid-binding protein
J4N43_05335	COG0416	fatty acid biosynthetic process
J4N43_05340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J4N43_05370	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J4N43_05375	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J4N43_05380	COG0470	DNA polymerase III
J4N43_05385	COG0084	hydrolase, TatD family'
J4N43_05390	COG1263	PTS System
J4N43_05390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N43_05405	COG0733	neurotransmitter:sodium symporter activity
J4N43_05420	COG4667	esterase of the alpha-beta hydrolase superfamily
J4N43_05425	COG0469	pyruvate kinase activity
J4N43_05430	COG1940	carbohydrate kinase activity
J4N43_05435	COG0784	Response regulator, receiver
J4N43_05435	COG0835	chemotaxis
J4N43_05440	COG0587	DNA-directed DNA polymerase activity
J4N43_05455	COG1028	Short-chain dehydrogenase reductase Sdr
J4N43_05460	COG0616	signal peptide processing
J4N43_05465	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J4N43_05470	COG0539	negative regulation of cytoplasmic translation
J4N43_05480	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
J4N43_05485	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
J4N43_05495	COG4166	transmembrane transport
J4N43_05515	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J4N43_05515	COG3008	intermembrane lipid transfer
J4N43_05520	COG2995	paraquat-inducible protein a
J4N43_05525	COG3258	Cytochrome c
J4N43_05530	COG2863	cytochrome
J4N43_05565	COG4232	protein-disulfide reductase activity
J4N43_05570	COG3118	belongs to the thioredoxin family
J4N43_05580	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J4N43_05595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N43_05605	COG1136	(ABC) transporter
J4N43_05605	COG0577	efflux transmembrane transporter activity
J4N43_05615	COG0577	efflux transmembrane transporter activity
J4N43_05615	COG1136	(ABC) transporter
J4N43_05670	COG3850	Histidine kinase
J4N43_05670	COG5002	protein histidine kinase activity
J4N43_05675	COG0745	RESPONSE REGULATOR receiver
J4N43_05680	COG0463	Glycosyl transferase, family 2
J4N43_05685	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
J4N43_05715	COG5001	Diguanylate cyclase
J4N43_05730	COG0583	DNA-binding transcription factor activity
J4N43_05735	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J4N43_05745	COG2350	Protein conserved in bacteria
J4N43_05755	COG2917	probably involved in intracellular septation
J4N43_05775	COG1301	dicarboxylic acid transport
J4N43_05780	COG0318	PFAM AMP-dependent synthetase and ligase
J4N43_05785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N43_05790	COG0159	tryptophan synthase activity
J4N43_05800	COG0134	indole-3-glycerol-phosphate synthase activity
J4N43_05800	COG0135	phosphoribosylanthranilate isomerase activity
J4N43_05810	COG0512	Glutamine amidotransferase of anthranilate synthase
J4N43_05815	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J4N43_05825	COG0613	PHP domain protein
J4N43_05830	COG0009	L-threonylcarbamoyladenylate synthase
J4N43_05840	COG1187	pseudouridine synthase activity
J4N43_05860	COG0417	DNA replication proofreading
J4N43_05865	COG2197	response regulator
J4N43_05870	COG0322	excinuclease ABC activity
J4N43_05910	COG0019	diaminopimelate decarboxylase activity
J4N43_05940	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4N43_05945	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4N43_05965	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
J4N43_05975	COG0437	4 iron, 4 sulfur cluster binding
J4N43_05980	COG3301	Polysulphide reductase, NrfD
J4N43_05985	COG1138	Cytochrome C-type biogenesis protein
J4N43_05995	COG3088	subunit of a heme lyase
J4N43_05995	COG4235	cytochrome complex assembly
J4N43_06005	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J4N43_06030	COG2989	Protein conserved in bacteria
J4N43_06035	COG3108	Peptidase M15
J4N43_06040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4N43_06055	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J4N43_06085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N43_06090	COG0840	transmembrane signaling receptor activity
J4N43_06110	COG1448	Aminotransferase
J4N43_06125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N43_06135	COG0017	Asparaginyl-tRNA synthetase
J4N43_06140	COG0840	transmembrane signaling receptor activity
J4N43_06145	COG0720	synthase
J4N43_06155	COG2200	EAL domain
J4N43_06160	COG1760	l-serine dehydratase
J4N43_06165	COG0814	amino acid
J4N43_06170	COG0494	nUDIX hydrolase
J4N43_06180	COG2205	protein histidine kinase activity
J4N43_06180	COG0784	Response regulator, receiver
J4N43_06185	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J4N43_06200	COG3106	COG3106 Predicted ATPase
J4N43_06205	COG3768	UPF0283 membrane protein
J4N43_06215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N43_06255	COG1942	4-Oxalocrotonate Tautomerase
J4N43_06275	COG2732	(Barnase) inhibitor
J4N43_06325	COG2026	Addiction module toxin, RelE StbE family
J4N43_06470	COG1335	isochorismatase
J4N43_06685	COG0110	maltose O-acetyltransferase activity
J4N43_06695	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J4N43_06715	COG5507	3-demethylubiquinone-9 3-methyltransferase
J4N43_06720	COG1280	lysine exporter protein (LysE YggA)
J4N43_06725	COG1280	lysine exporter protein (LysE YggA)
J4N43_06735	COG0729	surface antigen
J4N43_06740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4N43_06745	COG2272	Belongs to the type-B carboxylesterase lipase family
J4N43_06770	COG2985	domain, Protein
J4N43_06780	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
J4N43_06795	COG0583	DNA-binding transcription factor activity
J4N43_06810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N43_06825	COG3290	protein histidine kinase activity
J4N43_06830	COG4565	transcriptional regulatory protein
J4N43_06840	COG2207	Transcriptional regulator
J4N43_06845	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J4N43_06850	COG0363	glucosamine-6-phosphate deaminase activity
J4N43_06855	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J4N43_06880	COG3284	Transcriptional regulator
J4N43_06885	COG1012	belongs to the aldehyde dehydrogenase family
J4N43_06955	COG4669	(LipO)protein
J4N43_06975	COG3177	Filamentation induced by cAMP protein fic
J4N43_07005	COG2207	Transcriptional regulator
J4N43_07010	COG4792	protein secretion
J4N43_07015	COG4791	protein targeting
J4N43_07020	COG4794	Type iii secretion
J4N43_07025	COG4790	Type iii secretion
J4N43_07095	COG0457	Tetratricopeptide repeat
J4N43_07110	COG2358	TRAP transporter, solute receptor (TAXI family
J4N43_07115	COG0730	response to heat
J4N43_07150	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
J4N43_07155	COG0372	Belongs to the citrate synthase family
J4N43_07165	COG2828	Protein conserved in bacteria
J4N43_07190	COG0561	phosphatase activity
J4N43_07195	COG0602	queuosine metabolic process
J4N43_07200	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J4N43_07215	COG0583	DNA-binding transcription factor activity
J4N43_07220	COG0583	DNA-binding transcription factor activity
J4N43_07235	COG0583	DNA-binding transcription factor activity
J4N43_07250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N43_07255	COG0765	amino acid transport
J4N43_07260	COG1126	abc transporter atp-binding protein
J4N43_07265	COG1410	methionine synthase
J4N43_07265	COG0646	methionine synthase
J4N43_07280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N43_07285	COG1335	isochorismatase
J4N43_07295	COG0604	alcohol dehydrogenase
J4N43_07305	COG2814	Major facilitator Superfamily
J4N43_07310	COG0583	DNA-binding transcription factor activity
J4N43_07320	COG0583	DNA-binding transcription factor activity
J4N43_07325	COG0656	L-ascorbic acid biosynthetic process
J4N43_07335	COG1414	Transcriptional regulator
J4N43_07340	COG2203	Gaf domain
J4N43_07340	COG2199	diguanylate cyclase activity
J4N43_07365	COG2885	chlorophyll binding
J4N43_07390	COG1254	Belongs to the acylphosphatase family
J4N43_07395	COG2920	part of a sulfur-relay system
J4N43_07405	COG0670	Belongs to the BI1 family
J4N43_07410	COG1126	abc transporter atp-binding protein
J4N43_07415	COG0765	amino acid transport
J4N43_07420	COG4597	amino acid ABC transporter
J4N43_07425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N43_07435	COG1666	GTP binding
J4N43_07440	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4N43_07465	COG3008	intermembrane lipid transfer
J4N43_07470	COG2995	paraquat-inducible protein a
J4N43_07475	COG1132	(ABC) transporter
J4N43_07480	COG1956	GAF domain-containing protein
J4N43_07485	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
J4N43_07500	COG0308	aminopeptidase N
J4N43_07510	COG2902	Dehydrogenase
J4N43_07515	COG0167	dihydroorotate dehydrogenase activity
J4N43_07525	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J4N43_07525	COG0116	Belongs to the methyltransferase superfamily
J4N43_07535	COG0488	(ABC) transporter
J4N43_07550	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J4N43_07555	COG1067	ATP-dependent peptidase activity
J4N43_07560	COG3120	sequence-specific DNA binding
J4N43_07590	COG2205	protein histidine kinase activity
J4N43_07590	COG0784	Response regulator, receiver
J4N43_07605	COG3278	Belongs to the heme-copper respiratory oxidase family
J4N43_07620	COG2010	Cytochrome c
J4N43_07630	COG2217	Heavy metal translocating P-type atpase
J4N43_07645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N43_07650	COG0589	response to stress
J4N43_07675	COG3842	ATPase activity
J4N43_07685	COG1177	transmembrane transport
J4N43_07695	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J4N43_07700	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J4N43_07710	COG0004	ammonium transporteR
J4N43_07745	COG4282	regulation of fungal-type cell wall biogenesis
J4N43_07810	COG0437	4 iron, 4 sulfur cluster binding
J4N43_07815	COG3383	formate dehydrogenase (NAD+) activity
J4N43_07815	COG0243	molybdopterin cofactor binding
J4N43_07825	COG3381	protein complex oligomerization
J4N43_07845	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J4N43_07850	COG0488	(ABC) transporter
J4N43_07855	COG4191	Histidine kinase
J4N43_07860	COG2204	response regulator
J4N43_07875	COG3842	ATPase activity
J4N43_07880	COG0746	molybdenum cofactor guanylyltransferase activity
J4N43_07885	COG0303	'Molybdopterin
J4N43_07895	COG1940	carbohydrate kinase activity
J4N43_07900	COG3148	PFAM DTW domain containing protein
J4N43_07930	COG0791	NLP P60 protein
J4N43_07940	COG3706	GGDEF domain
J4N43_07950	COG3001	Fructosamine kinase
J4N43_07960	COG0307	riboflavin synthase, alpha
J4N43_07965	COG0534	Mate efflux family protein
J4N43_07975	COG1793	dna ligase
J4N43_08005	COG2204	response regulator
J4N43_08010	COG0297	glycogen (starch) synthase activity
J4N43_08015	COG0438	transferase activity, transferring glycosyl groups
J4N43_08045	COG0438	transferase activity, transferring glycosyl groups
J4N43_08050	COG1215	transferase activity, transferring glycosyl groups
J4N43_08055	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J4N43_08065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N43_08080	COG1643	Atp-dependent helicase
J4N43_08085	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J4N43_08135	COG0443	Heat shock 70 kDa protein
J4N43_08155	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
J4N43_08160	COG0583	DNA-binding transcription factor activity
J4N43_08175	COG1132	(ABC) transporter
J4N43_08180	COG1132	(ABC) transporter
J4N43_08190	COG4774	siderophore transport
J4N43_08200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4N43_08205	COG1120	ATPase activity
J4N43_08220	COG0814	amino acid
J4N43_08230	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J4N43_08240	COG0861	Integral membrane protein TerC family
J4N43_08250	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J4N43_08255	COG1328	CTP reductase activity
J4N43_08270	COG3300	MHYT domain
J4N43_08270	COG5001	Diguanylate cyclase
J4N43_08285	COG0471	metal ion transport
J4N43_08310	COG4702	Belongs to the UPF0303 family
J4N43_08315	COG0673	inositol 2-dehydrogenase activity
J4N43_08320	COG1349	DNA-binding transcription factor activity
J4N43_08335	COG1538	Outer membrane efflux protein
J4N43_08360	COG3119	arylsulfatase activity
J4N43_08375	COG0641	radical SAM
J4N43_08390	COG3119	arylsulfatase activity
J4N43_08395	COG0527	aspartate kinase activity
J4N43_08400	COG0662	Cupin 2, conserved barrel domain protein
J4N43_08405	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J4N43_08410	COG0456	acetyltransferase
J4N43_08415	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N43_08435	COG4176	ABC-type proline glycine betaine transport system permease component
J4N43_08440	COG2113	Glycine betaine
J4N43_08445	COG1368	sulfuric ester hydrolase activity
J4N43_08470	COG1115	amino acid carrier protein
J4N43_08480	COG1280	lysine exporter protein (LysE YggA)
J4N43_08485	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
J4N43_08490	COG1560	Kdo2-lipid A biosynthetic process
J4N43_08505	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
J4N43_08510	COG3063	Type IV pilus biogenesis stability protein PilW
J4N43_08550	COG2315	Protein conserved in bacteria
J4N43_08555	COG1846	Transcriptional regulator
J4N43_08565	COG2200	EAL domain
J4N43_08570	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J4N43_08575	COG1012	belongs to the aldehyde dehydrogenase family
J4N43_08580	COG2957	Belongs to the agmatine deiminase family
J4N43_08590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4N43_08595	COG1012	belongs to the aldehyde dehydrogenase family
J4N43_08600	COG1396	sequence-specific DNA binding
J4N43_08600	COG1917	Cupin 2, conserved barrel domain protein
J4N43_08605	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
J4N43_08610	COG0174	glutamine synthetase
J4N43_08615	COG1757	Na H antiporter
J4N43_08630	COG1742	UPF0060 membrane protein
J4N43_08655	COG3755	Protein conserved in bacteria
J4N43_08705	COG0625	glutathione transferase activity
J4N43_08715	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
J4N43_08725	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4N43_08735	COG0601	transmembrane transport
J4N43_08740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N43_08760	COG3291	Pkd domain containing protein
J4N43_08770	COG1177	transmembrane transport
J4N43_08780	COG3842	ATPase activity
J4N43_08785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J4N43_08790	COG2423	ornithine cyclodeaminase activity
J4N43_08805	COG3938	Belongs to the proline racemase family
J4N43_08840	COG1451	nucleotide metabolic process
J4N43_08850	COG0583	DNA-binding transcription factor activity
J4N43_08870	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
J4N43_08875	COG4139	cobalamin transport
J4N43_08880	COG2988	succinylglutamate desuccinylase activity
J4N43_08900	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J4N43_08905	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J4N43_08910	COG0702	epimerase
J4N43_08915	COG1823	symporter activity
J4N43_08920	COG2925	Exonuclease
J4N43_08925	COG1380	Effector of murein hydrolase LrgA
J4N43_08930	COG1346	cytolysis
J4N43_08935	COG0295	cytidine deaminase activity
J4N43_08940	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J4N43_08945	COG0500	methyltransferase
J4N43_08955	COG0776	regulation of translation
J4N43_08965	COG0072	phenylalanine-tRNA ligase activity
J4N43_08965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4N43_08970	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
J4N43_09005	COG0393	Putative heavy-metal-binding
J4N43_09015	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J4N43_09025	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J4N43_09040	COG2188	Transcriptional regulator
J4N43_09045	COG1228	amidohydrolase
J4N43_09050	COG0010	Belongs to the arginase family
J4N43_09055	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
J4N43_09060	COG2986	histidine ammonia-lyase
J4N43_09075	COG0247	lactate metabolic process
J4N43_09075	COG0277	FAD linked oxidase domain protein
J4N43_09180	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J4N43_09195	COG1643	Atp-dependent helicase
J4N43_09200	COG0281	malic enzyme
J4N43_09205	COG2949	membrane
J4N43_09210	COG0471	metal ion transport
J4N43_09235	COG0492	ferredoxin-NADP+ reductase activity
J4N43_09240	COG4988	ABC transporter
J4N43_09245	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J4N43_09255	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J4N43_09265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N43_09265	COG4191	Histidine kinase
J4N43_09280	COG3070	regulator of competence-specific genes
J4N43_09290	COG2431	L-lysine efflux transmembrane transporter activity
J4N43_09300	COG0076	glutamate decarboxylase activity
J4N43_09305	COG1737	Transcriptional regulator
J4N43_09315	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J4N43_09320	COG3273	potassium ion transport
J4N43_09320	COG2985	domain, Protein
J4N43_09325	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J4N43_09330	COG1960	acyl-CoA dehydrogenase activity
J4N43_09340	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J4N43_09360	COG0534	Mate efflux family protein
J4N43_09365	COG0702	epimerase
J4N43_09375	COG2814	Major facilitator Superfamily
J4N43_09380	COG1187	pseudouridine synthase activity
J4N43_09385	COG1061	Type III restriction enzyme res subunit
J4N43_09405	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J4N43_09425	COG3313	Fe-S protein
J4N43_09435	COG4134	Bacterial extracellular solute-binding protein
J4N43_09440	COG4135	transport system, permease component
J4N43_09445	COG4136	ATPase activity
J4N43_09450	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J4N43_09460	COG3604	Transcriptional regulator
J4N43_09465	COG1151	hydroxylamine reductase activity
J4N43_09470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4N43_09480	COG0564	pseudouridine synthase activity
J4N43_09485	COG0733	neurotransmitter:sodium symporter activity
J4N43_09495	COG0626	cystathionine gamma-synthase activity
J4N43_09500	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J4N43_09505	COG5380	lipid catabolic process
J4N43_09510	COG2818	Glycosylase
J4N43_09530	COG1983	PspC domain protein
J4N43_09540	COG1842	Phage shock protein A
J4N43_09545	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
J4N43_09560	COG4171	peptide transport system, permease
J4N43_09570	COG4172	Belongs to the ABC transporter superfamily
J4N43_09580	COG1227	inorganic diphosphatase activity
J4N43_09595	COG0243	molybdopterin cofactor binding
J4N43_09600	COG3005	denitrification pathway
J4N43_09605	COG4459	periplasmic nitrate reductase
J4N43_09610	COG0390	transport system, permease component
J4N43_09620	COG2116	formate transmembrane transporter activity
J4N43_09645	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J4N43_09650	COG1435	thymidine kinase activity
J4N43_09655	COG0215	cysteine-tRNA ligase activity
J4N43_09660	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J4N43_09665	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4N43_09670	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J4N43_09675	COG3012	SEC-C Motif Domain Protein
J4N43_09680	COG0140	phosphoribosyl-ATP diphosphatase activity
J4N43_09680	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J4N43_09690	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J4N43_09695	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J4N43_09700	COG0131	Imidazoleglycerol-phosphate dehydratase
J4N43_09700	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J4N43_09710	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J4N43_09720	COG1757	Na H antiporter
J4N43_09730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N43_09745	COG2915	High frequency lysogenization protein hflD homolog
J4N43_09750	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J4N43_09760	COG2268	Band 7 protein
J4N43_09770	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J4N43_09785	COG0300	oxidoreductase activity
J4N43_09805	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J4N43_09825	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J4N43_09830	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J4N43_09850	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J4N43_09860	COG1674	ftsk spoiiie
J4N43_09870	COG0686	Belongs to the AlaDH PNT family
J4N43_09880	COG0583	DNA-binding transcription factor activity
J4N43_09905	COG3568	Endonuclease Exonuclease Phosphatase
J4N43_09930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N43_09935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N43_09955	COG1271	oxidase subunit
J4N43_09960	COG1294	oxidase, subunit
J4N43_10055	COG2433	Pfam Transposase IS66
J4N43_10075	COG1196	nuclear chromosome segregation
J4N43_10090	COG1401	restriction endodeoxyribonuclease activity
J4N43_10125	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
J4N43_10190	COG0582	viral genome integration into host DNA
J4N43_10205	COG0784	Response regulator, receiver
J4N43_10205	COG5002	protein histidine kinase activity
J4N43_10215	COG0754	glutathionylspermidine amidase activity
J4N43_10225	COG3766	membrane
J4N43_10235	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J4N43_10240	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
J4N43_10245	COG2885	chlorophyll binding
J4N43_10250	COG0823	Involved in the tonB-independent uptake of proteins
J4N43_10265	COG0811	peptide transport
J4N43_10270	COG0824	Thioesterase
J4N43_10280	COG4890	Cyd operon protein YbgT
J4N43_10285	COG1294	oxidase, subunit
J4N43_10290	COG1271	oxidase subunit
J4N43_10295	COG2255	four-way junction helicase activity
J4N43_10300	COG0632	four-way junction helicase activity
J4N43_10305	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J4N43_10310	COG0217	transcriptional regulatory protein
J4N43_10320	COG1801	Protein of unknown function DUF72
J4N43_10330	COG0500	methyltransferase
J4N43_10335	COG0189	ligase activity
J4N43_10335	COG4067	protein conserved in archaea
J4N43_10355	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J4N43_10360	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
J4N43_10365	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
J4N43_10370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4N43_10375	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J4N43_10380	COG0745	RESPONSE REGULATOR receiver
J4N43_10385	COG3381	protein complex oligomerization
J4N43_10390	COG1609	Transcriptional regulator
J4N43_10395	COG3070	regulator of competence-specific genes
J4N43_10415	COG0297	glycogen (starch) synthase activity
J4N43_10420	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J4N43_10425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4N43_10445	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J4N43_10450	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
J4N43_10455	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J4N43_10460	COG0542	response to heat
J4N43_10465	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
J4N43_10470	COG1278	Cold shock
J4N43_10480	COG1187	pseudouridine synthase activity
J4N43_10485	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
J4N43_10490	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J4N43_10495	COG1199	ATP-dependent helicase activity
J4N43_10500	COG0730	response to heat
J4N43_10505	COG3923	Primosomal replication protein n
J4N43_10515	COG0708	Exodeoxyribonuclease III
J4N43_10555	COG1882	Formate acetyltransferase
J4N43_10565	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J4N43_10575	COG3013	Belongs to the UPF0304 family
J4N43_10580	COG2766	serine protein kinase
J4N43_10585	COG2718	Belongs to the UPF0229 family
J4N43_10590	COG2719	SpoVR family
J4N43_10610	COG1132	(ABC) transporter
J4N43_10615	COG0658	competence protein
J4N43_10615	COG2333	competence protein COMEC
J4N43_10625	COG4591	ABC-type transport system involved in lipoprotein release permease component
J4N43_10630	COG1136	(ABC) transporter
J4N43_10635	COG4591	ABC-type transport system involved in lipoprotein release permease component
J4N43_10645	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J4N43_10660	COG1252	NADH dehydrogenase
J4N43_10665	COG3150	esterase
J4N43_10690	COG0537	adenosine 5'-monophosphoramidase activity
J4N43_10715	COG0517	IMP dehydrogenase activity
J4N43_10715	COG0516	GMP reductase activity
J4N43_10720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4N43_10765	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J4N43_10785	COG0732	type I restriction modification DNA specificity domain
J4N43_10850	COG3126	Type III secretion system lipoprotein chaperone (YscW)
J4N43_10855	COG1946	Acyl-CoA thioesterase
J4N43_10865	COG1522	sequence-specific DNA binding
J4N43_10870	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J4N43_10885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N43_10890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N43_10935	COG0477	Major facilitator Superfamily
J4N43_10940	COG2855	membrane
J4N43_10960	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
J4N43_10970	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
J4N43_10975	COG1169	isochorismate synthase
J4N43_10980	COG0436	Aminotransferase
J4N43_10985	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
J4N43_10990	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J4N43_11005	COG1555	photosystem II stabilization
J4N43_11010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4N43_11015	COG0776	regulation of translation
J4N43_11020	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J4N43_11025	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J4N43_11035	COG0544	peptidyl-prolyl cis-trans isomerase activity
J4N43_11050	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N43_11055	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J4N43_11060	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J4N43_11065	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
J4N43_11080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4N43_11085	COG0569	domain protein
J4N43_11090	COG0513	Belongs to the DEAD box helicase family
J4N43_11125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4N43_11130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J4N43_11145	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J4N43_11150	COG1216	Glycosyl transferase, family 2
J4N43_11155	COG2986	histidine ammonia-lyase
J4N43_11180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J4N43_11190	COG1028	Short-chain dehydrogenase reductase Sdr
J4N43_11200	COG2226	methyltransferase
J4N43_11210	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J4N43_11215	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4N43_11225	COG2951	lytic endotransglycosylase activity
J4N43_11230	COG3100	YcgL domain-containing protein
J4N43_11235	COG0850	regulation of cytokinetic process
J4N43_11240	COG2894	cell division
J4N43_11245	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
J4N43_11250	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
J4N43_11255	COG0318	PFAM AMP-dependent synthetase and ligase
J4N43_11260	COG2267	carboxylic ester hydrolase activity
J4N43_11265	COG3065	identical protein binding
J4N43_11275	COG1214	PFAM Peptidase M22, glycoprotease
J4N43_11280	COG1199	ATP-dependent helicase activity
J4N43_11285	COG0788	formyltetrahydrofolate deformylase activity
J4N43_11290	COG3102	Protein conserved in bacteria
J4N43_11295	COG0018	arginyl-trna synthetase
J4N43_11320	COG1918	ferrous iron import across plasma membrane
J4N43_11325	COG4977	sequence-specific DNA binding
J4N43_11330	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
J4N43_11335	COG1121	(ABC) transporter
J4N43_11340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J4N43_11350	COG0045	succinate-CoA ligase (ADP-forming) activity
J4N43_11355	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4N43_11360	COG0567	Dehydrogenase, E1 component
J4N43_11365	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J4N43_11370	COG1053	succinate dehydrogenase
J4N43_11375	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
J4N43_11390	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J4N43_11400	COG0033	Phosphoglucomutase
J4N43_11405	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
J4N43_11410	COG0596	Alpha beta hydrolase
J4N43_11420	COG0716	FMN binding
J4N43_11430	COG0735	belongs to the Fur family
J4N43_11435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J4N43_11440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N43_11440	COG2190	(PTS) system
J4N43_11440	COG1263	PTS System
J4N43_11445	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J4N43_11450	COG1940	carbohydrate kinase activity
J4N43_11450	COG1846	Transcriptional regulator
J4N43_11455	COG4651	solute:proton antiporter activity
J4N43_11455	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J4N43_11460	COG0367	asparagine synthase
J4N43_11465	COG0250	Participates in transcription elongation, termination and antitermination
J4N43_11470	COG3104	oligopeptide transport
J4N43_11485	COG0326	Molecular chaperone. Has ATPase activity
J4N43_11490	COG3710	Transcriptional regulator
J4N43_11510	COG0622	Phosphoesterase
J4N43_11540	COG1090	epimerase
J4N43_11545	COG0300	oxidoreductase activity
J4N43_11550	COG3118	belongs to the thioredoxin family
J4N43_11555	COG0330	HflC and HflK could
J4N43_11575	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J4N43_11580	COG3115	cell septum assembly
J4N43_11585	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
J4N43_11590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J4N43_11595	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N43_11600	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J4N43_11605	COG2190	(PTS) system
J4N43_11610	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N43_11620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N43_11625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N43_11635	COG1705	Flagellar rod assembly protein muramidase FlgJ
J4N43_11635	COG3951	Flagellar rod assembly protein muramidase FlgJ
J4N43_11640	COG1706	bacterial-type flagellum-dependent cell motility
J4N43_11645	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J4N43_11655	COG4787	bacterial-type flagellum-dependent cell motility
J4N43_11660	COG1749	Flagellar hook protein flgE
J4N43_11670	COG1558	bacterial-type flagellum-dependent cell motility
J4N43_11675	COG1815	bacterial-type flagellum-dependent cell motility
J4N43_11685	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J4N43_11690	COG0784	Response regulator, receiver
J4N43_11690	COG0835	chemotaxis
J4N43_11745	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
J4N43_11755	COG2217	Heavy metal translocating P-type atpase
J4N43_11755	COG2608	mercury ion transmembrane transporter activity
J4N43_11795	COG2840	Smr protein MutS2
J4N43_11800	COG1187	pseudouridine synthase activity
J4N43_11805	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J4N43_11810	COG0737	Belongs to the 5'-nucleotidase family
J4N43_11815	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J4N43_11820	COG2912	Transglutaminase-like superfamily
J4N43_11825	COG3094	Invasion gene expression up-regulator, SirB
J4N43_11830	COG2890	protein-(glutamine-N5) methyltransferase activity
J4N43_11840	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J4N43_11845	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
J4N43_11850	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J4N43_11855	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J4N43_11860	COG0193	aminoacyl-tRNA hydrolase activity
J4N43_11865	COG0012	GTP binding
J4N43_11970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N43_11975	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J4N43_11980	COG1702	phosphate starvation-inducible protein PhoH
J4N43_11985	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J4N43_11990	COG4535	Mg2 and Co2 transporter CorC
J4N43_11995	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J4N43_12005	COG2888	peptidyl-tyrosine sulfation
J4N43_12010	COG0495	leucyl-tRNA aminoacylation
J4N43_12015	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
J4N43_12020	COG1466	dna polymerase III delta subunit
J4N43_12025	COG0799	negative regulation of ribosome biogenesis
J4N43_12030	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J4N43_12035	COG0768	penicillin binding
J4N43_12040	COG0772	Belongs to the SEDS family
J4N43_12045	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J4N43_12050	COG1686	Belongs to the peptidase S11 family
J4N43_12060	COG0321	lipoyl(octanoyl) transferase activity
J4N43_12065	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J4N43_12070	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J4N43_12075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4N43_12090	COG0366	Alpha amylase catalytic
J4N43_12095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N43_12095	COG1263	PTS System
J4N43_12105	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J4N43_12110	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J4N43_12115	COG2011	ABC-type metal ion transport system permease component
J4N43_12120	COG1464	Belongs to the NlpA lipoprotein family
J4N43_12125	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
J4N43_12135	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J4N43_12135	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J4N43_12150	COG1611	Belongs to the LOG family
J4N43_12155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4N43_12165	COG2363	Small membrane protein
J4N43_12175	COG0583	DNA-binding transcription factor activity
J4N43_12180	COG0301	tRNA thio-modification
J4N43_12180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4N43_12190	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J4N43_12195	COG1722	exodeoxyribonuclease VII activity
J4N43_12200	COG0142	geranyltranstransferase activity
J4N43_12205	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J4N43_12210	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J4N43_12215	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J4N43_12225	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
J4N43_12240	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4N43_12240	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4N43_12245	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J4N43_12250	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J4N43_12255	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J4N43_12265	COG1073	alpha beta
J4N43_12270	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
J4N43_12275	COG2252	PERMEase
J4N43_12280	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4N43_12310	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J4N43_12310	COG0047	phosphoribosylformylglycinamidine synthase activity
J4N43_12315	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
J4N43_12325	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J4N43_12355	COG0484	heat shock protein binding
J4N43_12365	COG1301	dicarboxylic acid transport
J4N43_12370	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J4N43_12375	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J4N43_12385	COG0497	DNA recombination
J4N43_12395	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N43_12400	COG2914	Belongs to the UPF0125 (RnfH) family
J4N43_12405	COG2867	negative regulation of translational initiation
J4N43_12410	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J4N43_12455	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
J4N43_12485	COG0328	RNA-DNA hybrid ribonuclease activity
J4N43_12520	COG0583	DNA-binding transcription factor activity
J4N43_12525	COG3153	acetyltransferase
J4N43_12525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J4N43_12545	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J4N43_12550	COG2873	o-acetylhomoserine
J4N43_12565	COG1115	amino acid carrier protein
J4N43_12570	COG1584	GPR1 FUN34 yaaH family protein
J4N43_12580	COG1757	Na H antiporter
J4N43_12590	COG0516	GMP reductase activity
J4N43_12590	COG0517	IMP dehydrogenase activity
J4N43_12610	COG1160	GTP binding
J4N43_12615	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N43_12620	COG2976	Protein conserved in bacteria
J4N43_12625	COG0124	histidyl-tRNA synthetase
J4N43_12630	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J4N43_12645	COG0105	UTP biosynthetic process
J4N43_12655	COG2975	iron-sulfur cluster assembly
J4N43_12660	COG0633	Ferredoxin
J4N43_12665	COG0443	Heat shock 70 kDa protein
J4N43_12680	COG0822	iron-sulfur transferase activity
J4N43_12685	COG1104	cysteine desulfurase activity
J4N43_12695	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
J4N43_12700	COG0483	inositol monophosphate 1-phosphatase activity
J4N43_12715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N43_12720	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N43_12725	COG1862	Preprotein translocase
J4N43_12735	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J4N43_12745	COG0517	IMP dehydrogenase activity
J4N43_12755	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J4N43_12760	COG0583	DNA-binding transcription factor activity
J4N43_12765	COG0450	alkyl hydroperoxide reductase
J4N43_12770	COG3142	Participates in the control of copper homeostasis
J4N43_12780	COG0704	Plays a role in the regulation of phosphate uptake
J4N43_12785	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4N43_12790	COG0581	inorganic phosphate transmembrane transporter activity
J4N43_12795	COG0573	inorganic phosphate transmembrane transporter activity
J4N43_12800	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J4N43_12805	COG0248	Ppx GppA phosphatase
J4N43_12815	COG5002	protein histidine kinase activity
J4N43_12820	COG0745	RESPONSE REGULATOR receiver
J4N43_12825	COG2974	May be involved in recombination
J4N43_12830	COG0826	peptidase U32
J4N43_12835	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J4N43_12890	COG0542	response to heat
J4N43_12900	COG0564	pseudouridine synthase activity
J4N43_12905	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N43_12915	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J4N43_12920	COG1605	Chorismate mutase
J4N43_12920	COG0077	Prephenate dehydratase
J4N43_12925	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
J4N43_12930	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
J4N43_12940	COG0488	(ABC) transporter
J4N43_12950	COG0739	heme binding
J4N43_12955	COG0287	Prephenate dehydrogenase
J4N43_12955	COG1605	Chorismate mutase
J4N43_12960	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4N43_12965	COG1472	Belongs to the glycosyl hydrolase 3 family
J4N43_12970	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
J4N43_12990	COG1966	Carbon starvation protein
J4N43_12995	COG3275	phosphorelay sensor kinase activity
J4N43_13000	COG3279	Response regulator of the LytR AlgR family
J4N43_13010	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J4N43_13015	COG1047	Peptidyl-prolyl cis-trans
J4N43_13030	COG0196	riboflavin kinase activity
J4N43_13035	COG0728	peptidoglycan biosynthetic process
J4N43_13040	COG0268	Binds directly to 16S ribosomal RNA
J4N43_13050	COG0640	Transcriptional regulator
J4N43_13055	COG0583	DNA-binding transcription factor activity
J4N43_13060	COG1283	sodium-dependent phosphate transmembrane transporter activity
J4N43_13070	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J4N43_13075	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J4N43_13080	COG0730	response to heat
J4N43_13105	COG0667	Aldo Keto reductase
J4N43_13115	COG2204	response regulator
J4N43_13130	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J4N43_13135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4N43_13140	COG4974	Belongs to the 'phage' integrase family
J4N43_13145	COG0716	FMN binding
J4N43_13155	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
J4N43_13160	COG0513	Belongs to the DEAD box helicase family
J4N43_13165	COG3022	response to hydroperoxide
J4N43_13170	COG1115	amino acid carrier protein
J4N43_13185	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J4N43_13190	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
J4N43_13195	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
J4N43_13205	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J4N43_13210	COG0083	homoserine kinase activity
J4N43_13230	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J4N43_13240	COG0745	RESPONSE REGULATOR receiver
J4N43_13250	COG0784	Response regulator, receiver
J4N43_13250	COG2198	Histidine kinase
J4N43_13250	COG5002	protein histidine kinase activity
J4N43_13260	COG1242	4 iron, 4 sulfur cluster binding
J4N43_13265	COG0070	glutamate synthase
J4N43_13265	COG0069	glutamate synthase activity
J4N43_13265	COG0067	glutamate synthase
J4N43_13275	COG0067	glutamate synthase
J4N43_13275	COG0069	glutamate synthase activity
J4N43_13275	COG0070	glutamate synthase
J4N43_13280	COG0493	'glutamate synthase
J4N43_13290	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J4N43_13305	COG2860	membrane
J4N43_13310	COG0583	DNA-binding transcription factor activity
J4N43_13315	COG0730	response to heat
J4N43_13330	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J4N43_13335	COG0505	Belongs to the CarA family
J4N43_13345	COG0494	nUDIX hydrolase
J4N43_13350	COG0653	protein targeting
J4N43_13360	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J4N43_13365	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J4N43_13370	COG0849	cell division
J4N43_13375	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J4N43_13390	COG0772	Belongs to the SEDS family
J4N43_13395	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J4N43_13400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J4N43_13405	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J4N43_13410	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J4N43_13415	COG0768	penicillin binding
J4N43_13420	COG3116	cell division
J4N43_13435	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J4N43_13450	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J4N43_13455	COG2823	Periplasmic or secreted lipoprotein
J4N43_13460	COG2969	positive regulation of protein catabolic process
J4N43_13465	COG0625	glutathione transferase activity
J4N43_13470	COG2857	Cytochrome c1
J4N43_13475	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J4N43_13480	COG0723	plastoquinol--plastocyanin reductase activity
J4N43_13485	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J4N43_13495	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J4N43_13500	COG3105	Protein conserved in bacteria
J4N43_13510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4N43_13515	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J4N43_13525	COG3150	esterase
J4N43_13535	COG3151	Protein conserved in bacteria
J4N43_13540	COG0494	nUDIX hydrolase
J4N43_13545	COG1538	Outer membrane efflux protein
J4N43_13550	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J4N43_13550	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J4N43_13555	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J4N43_13570	COG3025	triphosphatase activity
J4N43_13575	COG1392	Phosphate transport regulator
J4N43_13580	COG0306	phosphate transporter
J4N43_13585	COG4991	sh3 domain protein
J4N43_13590	COG0405	Gamma-glutamyltransferase
J4N43_13600	COG3267	Type II secretory pathway component ExeA
J4N43_13600	COG3409	Peptidoglycan-binding domain 1 protein
J4N43_13610	COG1968	undecaprenyl-diphosphatase activity
J4N43_13615	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J4N43_13620	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J4N43_13625	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J4N43_13630	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J4N43_13635	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J4N43_13640	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J4N43_13645	COG1610	YqeY-like protein
J4N43_13650	COG0358	DNA primase activity
J4N43_13720	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N43_13720	COG2213	PTS system mannitol-specific
J4N43_13730	COG3722	fumarate hydratase activity
J4N43_13745	COG1461	Dihydroxyacetone kinase
J4N43_13750	COG2376	Dihydroxyacetone kinase
J4N43_13760	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J4N43_13765	COG1349	DNA-binding transcription factor activity
J4N43_13770	COG0469	pyruvate kinase activity
J4N43_13785	COG0440	acetolactate synthase activity
J4N43_13790	COG0028	Belongs to the TPP enzyme family
J4N43_13795	COG1022	Amp-dependent synthetase and ligase
J4N43_13800	COG0583	DNA-binding transcription factor activity
J4N43_13820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J4N43_13825	COG0473	3-isopropylmalate dehydrogenase activity
J4N43_13845	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
J4N43_13850	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
J4N43_13855	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4N43_13860	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J4N43_13865	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J4N43_13870	COG2967	ApaG domain
J4N43_13875	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J4N43_13880	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J4N43_13890	COG2966	Psort location CytoplasmicMembrane, score
J4N43_13895	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J4N43_13905	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J4N43_13910	COG0142	geranyltranstransferase activity
J4N43_13930	COG2358	TRAP transporter, solute receptor (TAXI family
J4N43_13945	COG1902	pentaerythritol trinitrate reductase activity
J4N43_13950	COG0583	DNA-binding transcription factor activity
J4N43_13955	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
J4N43_13960	COG1178	ABC-type Fe3 transport system permease component
J4N43_13970	COG0163	prenyltransferase activity
J4N43_13975	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J4N43_13980	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
J4N43_13985	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J4N43_13995	COG2105	PFAM AIG2 family protein
J4N43_14000	COG2911	Protein conserved in bacteria
J4N43_14005	COG0729	surface antigen
J4N43_14010	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N43_14020	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
J4N43_14035	COG4181	ATPase activity
J4N43_14055	COG0529	Catalyzes the synthesis of activated sulfate
J4N43_14060	COG3273	potassium ion transport
J4N43_14060	COG0471	metal ion transport
J4N43_14065	COG2895	sulfate adenylyltransferase (ATP) activity
J4N43_14070	COG0175	sulfate reduction
J4N43_14075	COG1648	precorrin-2 dehydrogenase activity
J4N43_14075	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J4N43_14080	COG0737	Belongs to the 5'-nucleotidase family
J4N43_14090	COG0513	Belongs to the DEAD box helicase family
J4N43_14095	COG2153	protein acetylation
J4N43_14105	COG0545	Peptidyl-prolyl cis-trans isomerase
J4N43_14115	COG0203	ribosomal protein L17
J4N43_14120	COG0202	RNA polymerase activity
J4N43_14130	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J4N43_14135	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J4N43_14140	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J4N43_14145	COG0201	protein transport
J4N43_14150	COG0200	Binds to the 23S rRNA
J4N43_14155	COG1841	ribosomal large subunit assembly
J4N43_14170	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J4N43_14175	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J4N43_14185	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J4N43_14190	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J4N43_14200	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J4N43_14205	COG0255	Belongs to the universal ribosomal protein uL29 family
J4N43_14215	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J4N43_14220	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J4N43_14225	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J4N43_14230	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J4N43_14240	COG0088	Forms part of the polypeptide exit tunnel
J4N43_14245	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J4N43_14255	COG0254	rRNA binding
J4N43_14260	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J4N43_14265	COG1609	Transcriptional regulator
J4N43_14275	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
J4N43_14280	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
J4N43_14285	COG1575	Belongs to the MenA family. Type 1 subfamily
J4N43_14290	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J4N43_14300	COG1494	fructose-1,6-bisphosphatase
J4N43_14330	COG0149	triose-phosphate isomerase activity
J4N43_14350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J4N43_14360	COG1181	Belongs to the D-alanine--D-alanine ligase family
J4N43_14375	COG0728	peptidoglycan biosynthetic process
J4N43_14380	COG1216	Glycosyl transferase, family 2
J4N43_14380	COG1442	glycosyl transferase family 8
J4N43_14390	COG1083	cytidylyl-transferase
J4N43_14395	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J4N43_14405	COG2089	acid synthase
J4N43_14410	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J4N43_14415	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J4N43_14455	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N43_14465	COG1560	Kdo2-lipid A biosynthetic process
J4N43_14470	COG0859	PFAM glycosyl transferase family 9
J4N43_14475	COG1519	Transferase
J4N43_14490	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J4N43_14510	COG3642	lipopolysaccharide core region biosynthetic process
J4N43_14515	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J4N43_14520	COG0859	PFAM glycosyl transferase family 9
J4N43_14525	COG0463	Glycosyl transferase, family 2
J4N43_14570	COG2003	Belongs to the UPF0758 family
J4N43_14580	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J4N43_14585	COG1309	transcriptional regulator
J4N43_14590	COG1560	Kdo2-lipid A biosynthetic process
J4N43_14600	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J4N43_14605	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J4N43_14610	COG1561	YicC-like family, N-terminal region
J4N43_14620	COG4608	Belongs to the ABC transporter superfamily
J4N43_14625	COG0444	Belongs to the ABC transporter superfamily
J4N43_14630	COG0747	negative chemotaxis
J4N43_14635	COG4239	(ABC) transporter, permease
J4N43_14640	COG4174	ABC transporter (Permease)
J4N43_14660	COG0811	peptide transport
J4N43_14665	COG0848	biopolymer transport protein
J4N43_14680	COG0194	GDP metabolic process
J4N43_14685	COG1758	RNA polymerase activity
J4N43_14690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J4N43_14695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4N43_14700	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J4N43_14705	COG2233	PERMEase
J4N43_14725	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4N43_14735	COG2183	response to ionizing radiation
J4N43_14750	COG1040	competence protein
J4N43_14760	COG0494	nUDIX hydrolase
J4N43_14765	COG1218	3'(2'),5'-bisphosphate nucleotidase
J4N43_14775	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
J4N43_14780	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
J4N43_14785	COG3156	type II secretion system protein K
J4N43_14790	COG4795	General secretion pathway protein
J4N43_14795	COG2165	general secretion pathway protein
J4N43_14800	COG2165	general secretion pathway protein
J4N43_14805	COG2165	general secretion pathway protein
J4N43_14810	COG1459	type II secretion system
J4N43_14815	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4N43_14825	COG3031	protein transport across the cell outer membrane
J4N43_14830	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J4N43_14835	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
J4N43_14840	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
J4N43_14850	COG0456	acetyltransferase
J4N43_14855	COG1490	D-aminoacyl-tRNA deacylase activity
J4N43_14860	COG1295	ribonuclease BN
J4N43_14875	COG1217	gtp-binding protein TYPA
J4N43_14880	COG0174	glutamine synthetase
J4N43_14890	COG3852	Histidine kinase
J4N43_14895	COG2204	response regulator
J4N43_14905	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J4N43_14935	COG0218	Necessary for normal cell division and for the maintenance of normal septation
J4N43_14940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4N43_14940	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4N43_14945	COG0456	acetyltransferase
J4N43_14955	COG0084	hydrolase, TatD family'
J4N43_14960	COG0805	protein transport
J4N43_14965	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J4N43_14975	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J4N43_14980	COG3165	ubiquinone biosynthetic process from chorismate
J4N43_14985	COG2226	methyltransferase
J4N43_14990	COG1322	Protein conserved in bacteria
J4N43_15005	COG0628	permease
J4N43_15035	COG1597	lipid kinase activity
J4N43_15065	COG2081	HI0933 family
J4N43_15075	COG1528	Iron-storage protein
J4N43_15080	COG0589	response to stress
J4N43_15095	COG0742	ribosomal rna small subunit methyltransferase
J4N43_15100	COG5001	Diguanylate cyclase
J4N43_15100	COG5002	protein histidine kinase activity
J4N43_15105	COG1522	sequence-specific DNA binding
J4N43_15115	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J4N43_15120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N43_15145	COG1196	nuclear chromosome segregation
J4N43_15150	COG0583	DNA-binding transcription factor activity
J4N43_15155	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
J4N43_15160	COG0800	Aldolase
J4N43_15165	COG2610	gluconate transmembrane transporter activity
J4N43_15170	COG3265	gluconokinase activity
J4N43_15175	COG0129	dihydroxy-acid dehydratase activity
J4N43_15190	COG0583	DNA-binding transcription factor activity
J4N43_15195	COG1609	Transcriptional regulator
J4N43_15235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N43_15240	COG0601	transmembrane transport
J4N43_15245	COG4166	transmembrane transport
J4N43_15300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N43_15305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N43_15310	COG2960	long-chain fatty acid transporting porin activity
J4N43_15315	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J4N43_15320	COG0583	DNA-binding transcription factor activity
J4N43_15355	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J4N43_15370	COG0408	coproporphyrinogen oxidase activity
J4N43_15375	COG0009	L-threonylcarbamoyladenylate synthase
J4N43_15380	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J4N43_15385	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J4N43_15395	COG0551	DNA topoisomerase type I activity
J4N43_15400	COG2922	Belongs to the Smg family
J4N43_15405	COG0758	DNA mediated transformation
J4N43_15415	COG0242	peptide deformylase activity
J4N43_15420	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J4N43_15425	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J4N43_15425	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J4N43_15430	COG0569	domain protein
J4N43_15435	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4N43_15445	COG1272	protein, Hemolysin III
J4N43_15450	COG4326	sporulation control protein
J4N43_15460	COG3084	Protein conserved in bacteria
J4N43_15470	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J4N43_15475	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4N43_15480	COG0204	Acyl-transferase
J4N43_15490	COG0606	chelatase, subunit chli
J4N43_15500	COG3978	acetolactate synthase activity
J4N43_15505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J4N43_15510	COG0129	dihydroxy-acid dehydratase activity
J4N43_15520	COG0583	DNA-binding transcription factor activity
J4N43_15525	COG2814	Major facilitator Superfamily
J4N43_15535	COG0765	amino acid transport
J4N43_15545	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J4N43_15550	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J4N43_15555	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J4N43_15560	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J4N43_15565	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J4N43_15570	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J4N43_15580	COG0356	it plays a direct role in the translocation of protons across the membrane
J4N43_15585	COG3312	ion transport
J4N43_15590	COG1475	DNA binding
J4N43_15595	COG1192	Involved in chromosome partitioning
J4N43_15600	COG0357	Ribosomal RNA small subunit methyltransferase G
J4N43_15605	COG0445	tRNA wobble uridine modification
J4N43_15610	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J4N43_15620	COG0706	membrane insertase activity
J4N43_15630	COG0594	ribonuclease P activity
J4N43_15640	COG1126	abc transporter atp-binding protein
J4N43_15665	COG1444	tRNA N-acetyltransferase activity
J4N43_15685	COG3340	Belongs to the peptidase S51 family
J4N43_15690	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J4N43_15695	COG1263	PTS System
J4N43_15695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N43_15700	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
J4N43_15715	COG4166	transmembrane transport
J4N43_15760	COG0259	pyridoxamine-phosphate oxidase activity
J4N43_15785	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N43_15820	COG1132	(ABC) transporter
J4N43_15830	COG0513	Belongs to the DEAD box helicase family
J4N43_15835	COG2258	MOSC domain
J4N43_15890	COG3634	alkyl hydroperoxide reductase activity
J4N43_15900	COG1846	Transcriptional regulator
J4N43_15905	COG1764	response to oxidative stress
J4N43_15940	COG0577	efflux transmembrane transporter activity
J4N43_15945	COG1136	(ABC) transporter
J4N43_15955	COG0826	peptidase U32
J4N43_15965	COG0019	diaminopimelate decarboxylase activity
J4N43_15970	COG4264	IucA IucC family
J4N43_15995	COG4772	TonB-dependent receptor
J4N43_16000	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
J4N43_16005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N43_16010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N43_16015	COG1120	ATPase activity
J4N43_16020	COG0840	transmembrane signaling receptor activity
J4N43_16025	COG0612	Peptidase, M16
J4N43_16035	COG0739	heme binding
J4N43_16050	COG2814	Major facilitator Superfamily
J4N43_16055	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J4N43_16060	COG1609	Transcriptional regulator
J4N43_16065	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N43_16080	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J4N43_16080	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N43_16090	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J4N43_16095	COG1609	Transcriptional regulator
J4N43_16105	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J4N43_16145	COG1760	l-serine dehydratase
J4N43_16155	COG4580	involved in the transport of maltose and maltodextrins
J4N43_16175	COG2356	endonuclease I
J4N43_16195	COG1982	Orn Lys Arg decarboxylase major
J4N43_16200	COG0531	amino acid
J4N43_16210	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
J4N43_16215	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
J4N43_16220	COG1162	GTPase activity
J4N43_16225	COG1263	PTS System
J4N43_16225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N43_16230	COG1999	signal sequence binding
J4N43_16245	COG2909	trisaccharide binding
J4N43_16250	COG0058	SHG alpha-glucan phosphorylase activity
J4N43_16255	COG1640	4-alpha-glucanotransferase
J4N43_16260	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J4N43_16265	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4N43_16270	COG0366	Alpha amylase catalytic
J4N43_16285	COG3366	ferrous iron transmembrane transporter activity
J4N43_16290	COG0700	Nucleoside recognition
J4N43_16300	COG3339	Conserved Protein
J4N43_16315	COG1301	dicarboxylic acid transport
J4N43_16340	COG0489	protein tyrosine kinase activity
J4N43_16340	COG3206	protein involved in exopolysaccharide biosynthesis
J4N43_16360	COG2095	MarC family integral membrane protein
J4N43_16365	COG4667	esterase of the alpha-beta hydrolase superfamily
J4N43_16375	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
J4N43_16380	COG0415	Belongs to the DNA photolyase family
J4N43_16390	COG1054	Belongs to the UPF0176 family
J4N43_16400	COG1686	Belongs to the peptidase S11 family
J4N43_16425	COG0583	DNA-binding transcription factor activity
J4N43_16430	COG4628	conserved protein (DUF2132)
J4N43_16450	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
J4N43_16455	COG0628	permease
J4N43_16495	COG2814	Major facilitator Superfamily
J4N43_16505	COG0454	-acetyltransferase
J4N43_16515	COG0745	RESPONSE REGULATOR receiver
J4N43_16520	COG2205	protein histidine kinase activity
J4N43_16535	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J4N43_16540	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J4N43_16545	COG1882	Formate acetyltransferase
J4N43_16575	COG1360	Flagellar Motor Protein
J4N43_16580	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J4N43_16585	COG1191	sigma factor activity
J4N43_16590	COG1580	Controls the rotational direction of flagella during chemotaxis
J4N43_16605	COG1516	flagellar protein fliS
J4N43_16610	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J4N43_16620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N43_16635	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J4N43_16645	COG1987	bacterial-type flagellum assembly
J4N43_16685	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J4N43_16745	COG0346	lactoylglutathione lyase activity
J4N43_16770	COG0745	RESPONSE REGULATOR receiver
J4N43_16795	COG3300	MHYT domain
J4N43_16795	COG5001	Diguanylate cyclase
J4N43_16800	COG0156	8-amino-7-oxononanoate synthase activity
J4N43_16805	COG1063	alcohol dehydrogenase
J4N43_16840	COG0668	transmembrane transport
J4N43_16850	COG1304	FMN binding
J4N43_16855	COG1620	l-lactate permease
J4N43_16860	COG0583	DNA-binding transcription factor activity
J4N43_16865	COG1505	serine-type exopeptidase activity
J4N43_16870	COG4172	Belongs to the ABC transporter superfamily
J4N43_16880	COG1067	ATP-dependent peptidase activity
J4N43_16890	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J4N43_16910	COG1247	-acetyltransferase
J4N43_16915	COG0437	4 iron, 4 sulfur cluster binding
J4N43_16920	COG0348	domain, Protein
J4N43_16940	COG1122	ATPase activity
J4N43_16945	COG4720	Psort location CytoplasmicMembrane, score
J4N43_16950	COG1566	PFAM secretion protein HlyD family protein
J4N43_16975	COG0813	purine-nucleoside phosphorylase activity
J4N43_16980	COG3272	Protein of unknown function (DUF1722)
J4N43_16985	COG0789	Transcriptional regulator
J4N43_16990	COG0415	Belongs to the DNA photolyase family
J4N43_16995	COG1376	ErfK ybiS ycfS ynhG family protein
J4N43_16995	COG1388	LysM domain
J4N43_17005	COG0513	Belongs to the DEAD box helicase family
J4N43_17010	COG1770	oligopeptidase
J4N43_17015	COG4771	TonB-dependent receptor
J4N43_17045	COG0573	inorganic phosphate transmembrane transporter activity
J4N43_17050	COG0581	inorganic phosphate transmembrane transporter activity
J4N43_17055	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4N43_17070	COG2304	oxidoreductase activity
J4N43_17090	COG0714	Associated with various cellular activities
J4N43_17095	COG0840	transmembrane signaling receptor activity
J4N43_17105	COG2197	response regulator
J4N43_17140	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
J4N43_17145	COG1120	ATPase activity
J4N43_17150	COG4774	siderophore transport
J4N43_17155	COG1132	(ABC) transporter
J4N43_17160	COG2205	protein histidine kinase activity
J4N43_17160	COG2205	protein histidine kinase activity
J4N43_17165	COG0745	RESPONSE REGULATOR receiver
J4N43_17170	COG0569	domain protein
J4N43_17175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4N43_17180	COG0583	DNA-binding transcription factor activity
J4N43_17185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N43_17195	COG1012	belongs to the aldehyde dehydrogenase family
J4N43_17200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4N43_17205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4N43_17215	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
J4N43_17220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N43_17250	COG2084	Dehydrogenase
J4N43_17255	COG0753	catalase activity
J4N43_17265	COG2130	NADP-dependent
J4N43_17270	COG1309	transcriptional regulator
J4N43_17275	COG3097	Belongs to the UPF0267 family
J4N43_17330	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J4N43_17345	COG1175	transmembrane transport
J4N43_17350	COG3833	ABC-type maltose transport systems, permease component
J4N43_17380	COG2375	cellular response to nickel ion
J4N43_17380	COG1132	(ABC) transporter
J4N43_17385	COG4774	siderophore transport
J4N43_17390	COG4607	ABC-type enterochelin transport system periplasmic component
J4N43_17395	COG4605	iron ion homeostasis
J4N43_17400	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N43_17410	COG2354	Protein conserved in bacteria
J4N43_17415	COG0418	dihydroorotase activity
J4N43_17420	COG0401	homolog of Blt101
J4N43_17425	COG3217	Mosc domain protein beta barrel domain protein
J4N43_17425	COG0633	Ferredoxin
J4N43_17425	COG3217	Mosc domain protein beta barrel domain protein
J4N43_17425	COG0633	Ferredoxin
J4N43_17435	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J4N43_17480	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
J4N43_17485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N43_17495	COG0848	biopolymer transport protein
J4N43_17500	COG0811	peptide transport
J4N43_17505	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
J4N43_17515	COG3721	Heme iron utilization protein
J4N43_17520	COG0748	coenzyme F420 binding
J4N43_17530	COG0784	Response regulator, receiver
J4N43_17530	COG0835	chemotaxis
J4N43_17535	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4N43_17540	COG0534	Mate efflux family protein
J4N43_17545	COG0444	Belongs to the ABC transporter superfamily
J4N43_17550	COG4608	Belongs to the ABC transporter superfamily
J4N43_17555	COG0747	negative chemotaxis
J4N43_17565	COG1349	DNA-binding transcription factor activity
J4N43_17570	COG2084	Dehydrogenase
J4N43_17575	COG3395	kinase activity
J4N43_17580	COG0235	Class ii aldolase
J4N43_17585	COG3622	Belongs to the hyi family
J4N43_17590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4N43_17595	COG2610	gluconate transmembrane transporter activity
J4N43_17615	COG0583	DNA-binding transcription factor activity
J4N43_17620	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J4N43_17630	COG4934	collagen metabolic process
J4N43_17640	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J4N43_17645	COG0789	Transcriptional regulator
J4N43_17650	COG0366	Alpha amylase catalytic
J4N43_17670	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N43_17675	COG0589	response to stress
J4N43_17680	COG0488	(ABC) transporter
J4N43_17685	COG1505	serine-type exopeptidase activity
J4N43_17695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N43_17705	COG2067	long-chain fatty acid transport protein
J4N43_17715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N43_17740	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N43_17760	COG3383	formate dehydrogenase (NAD+) activity
J4N43_17770	COG0842	Transport permease protein
J4N43_17775	COG1131	(ABC) transporter
J4N43_17795	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
J4N43_17805	COG4145	pantothenate transmembrane transporter activity
J4N43_17810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N43_17815	COG0800	Aldolase
J4N43_17825	COG2706	6-phosphogluconolactonase activity
J4N43_17830	COG0251	oxidation-reduction process
J4N43_17840	COG1881	PFAM PEBP family protein
J4N43_17850	COG0798	PFAM Bile acid sodium symporter
J4N43_17865	COG1733	regulation of RNA biosynthetic process
J4N43_17890	COG4989	oxidoreductase activity
J4N43_17915	COG0814	amino acid
J4N43_17930	COG3314	Sporulation integral membrane protein YlbJ
J4N43_17950	COG0739	heme binding
J4N43_17955	COG5001	Diguanylate cyclase
J4N43_17960	COG0583	DNA-binding transcription factor activity
J4N43_17965	COG2814	Major facilitator Superfamily
J4N43_17985	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J4N43_17995	COG0179	Fumarylacetoacetate (FAA) hydrolase
J4N43_18015	COG1280	lysine exporter protein (LysE YggA)
J4N43_18025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4N43_18030	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J4N43_18035	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J4N43_18040	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
J4N43_18045	COG1845	cytochrome c oxidase, subunit III
J4N43_18065	COG1612	heme a metabolic process
J4N43_18070	COG0109	protoheme IX farnesyltransferase activity
J4N43_18075	COG0545	Peptidyl-prolyl cis-trans isomerase
J4N43_18105	COG1278	Cold shock
J4N43_18110	COG3036	rescue of stalled ribosome
J4N43_18115	COG2199	diguanylate cyclase activity
J4N43_18130	COG1132	(ABC) transporter
J4N43_18140	COG1538	Outer membrane efflux protein
J4N43_18145	COG0784	Response regulator, receiver
J4N43_18145	COG2205	protein histidine kinase activity
J4N43_18170	COG0840	transmembrane signaling receptor activity
J4N43_18175	COG0783	Belongs to the Dps family
J4N43_18185	COG2133	pyrroloquinoline quinone binding
J4N43_18190	COG1454	alcohol dehydrogenase
J4N43_18195	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
J4N43_18220	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4N43_18225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J4N43_18230	COG3186	Phenylalanine-4-hydroxylase
J4N43_18255	COG3530	Putative quorum-sensing-regulated virulence factor
J4N43_18305	COG0513	Belongs to the DEAD box helicase family
J4N43_18310	COG4628	conserved protein (DUF2132)
J4N43_18320	COG0133	tryptophan synthase activity
J4N43_18330	COG1278	Cold shock
J4N43_18340	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
J4N43_18350	COG0523	cobalamin synthesis protein
J4N43_18355	COG0513	Belongs to the DEAD box helicase family
J4N43_18375	COG2200	EAL domain
J4N43_18380	COG1119	ATPase activity
J4N43_18415	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
J4N43_18420	COG0513	Belongs to the DEAD box helicase family
J4N43_18430	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J4N43_18440	COG1073	alpha beta
J4N43_18445	COG1073	alpha beta
J4N43_18475	COG0735	belongs to the Fur family
J4N43_18480	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J4N43_18490	COG0523	cobalamin synthesis protein
J4N43_18500	COG0739	heme binding
J4N43_18505	COG0523	cobalamin synthesis protein
J4N43_18520	COG2095	MarC family integral membrane protein
J4N43_18545	COG1024	Enoyl-CoA hydratase
J4N43_18550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J4N43_18555	COG1960	acyl-CoA dehydrogenase activity
J4N43_18565	COG0183	Belongs to the thiolase family
J4N43_18580	COG1024	Enoyl-CoA hydratase
J4N43_18585	COG1024	Enoyl-CoA hydratase
J4N43_18595	COG1028	Short-chain dehydrogenase reductase Sdr
J4N43_18600	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J4N43_18605	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J4N43_18610	COG1845	cytochrome c oxidase, subunit III
J4N43_18615	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J4N43_18620	COG0109	protoheme IX farnesyltransferase activity
J4N43_18625	COG1902	pentaerythritol trinitrate reductase activity
J4N43_18625	COG0446	pyridine nucleotide-disulphide oxidoreductase
J4N43_18640	COG1012	belongs to the aldehyde dehydrogenase family
J4N43_18650	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N43_18680	COG1126	abc transporter atp-binding protein
J4N43_18685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N43_18690	COG4215	(ABC) transporter
J4N43_18695	COG4160	amino acid transport
J4N43_18765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N43_18770	COG2176	DNA-directed DNA polymerase activity
J4N43_18775	COG0517	IMP dehydrogenase activity
J4N43_18780	COG2186	Transcriptional regulator
J4N43_18785	COG2186	Transcriptional regulator
J4N43_18830	COG1917	Cupin 2, conserved barrel domain protein
J4N43_18835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N43_18840	COG0800	Aldolase
J4N43_18850	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J4N43_18855	COG1028	Short-chain dehydrogenase reductase Sdr
J4N43_18860	COG2847	Copper chaperone PCu(A)C
J4N43_18930	COG0814	amino acid
J4N43_18940	COG0243	molybdopterin cofactor binding
J4N43_18970	COG1116	anion transmembrane transporter activity
J4N43_18970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J4N43_18975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J4N43_18980	COG1116	anion transmembrane transporter activity
J4N43_19035	COG2815	serine threonine protein kinase
J4N43_19035	COG0515	serine threonine protein kinase
J4N43_19070	COG0631	protein serine/threonine phosphatase activity
J4N43_19140	COG0420	3'-5' exonuclease activity
J4N43_19145	COG0419	ATPase involved in DNA repair
J4N43_19155	COG3040	lipid binding
J4N43_19165	COG1288	antiporter activity
J4N43_19175	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
J4N43_19190	COG2425	protein containing a von Willebrand factor type A (vWA) domain
J4N43_19205	COG0583	DNA-binding transcription factor activity
J4N43_19210	COG0277	FAD linked oxidase domain protein
J4N43_19225	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J4N43_19275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J4N43_19295	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4N43_19300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4N43_19310	COG2116	formate transmembrane transporter activity
J4N43_19330	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J4N43_19365	COG3118	belongs to the thioredoxin family
J4N43_19370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J4N43_19395	COG2271	Major facilitator Superfamily
J4N43_19400	COG3851	Histidine kinase
J4N43_19405	COG2197	response regulator
J4N43_19415	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J4N43_19420	COG0583	DNA-binding transcription factor activity
J4N43_19425	COG0243	molybdopterin cofactor binding
J4N43_19440	COG0384	phenazine biosynthesis protein PhzF
J4N43_19445	COG1794	racemase activity, acting on amino acids and derivatives
J4N43_19475	COG1328	CTP reductase activity
J4N43_19480	COG0602	queuosine metabolic process
J4N43_19485	COG0534	Mate efflux family protein
J4N43_19490	COG2207	Transcriptional regulator
J4N43_19500	COG4067	protein conserved in archaea
J4N43_19500	COG0189	ligase activity
J4N43_19510	COG3111	PFAM Bacterial OB fold (BOF) protein
J4N43_19520	COG0725	ABC transporter, periplasmic molybdate-binding protein
J4N43_19525	COG4149	molybdate abc transporter
J4N43_19530	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
J4N43_19540	COG2203	Gaf domain
J4N43_19540	COG5001	Diguanylate cyclase
J4N43_19540	COG3706	GGDEF domain
J4N43_19540	COG4251	negative regulation of phosphorylation
J4N43_19560	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J4N43_19565	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
J4N43_19590	COG3140	Belongs to the UPF0181 family
J4N43_19605	COG0583	DNA-binding transcription factor activity
J4N43_19655	COG0023	Translation Initiation Factor
J4N43_19665	COG1181	Belongs to the D-alanine--D-alanine ligase family
J4N43_19675	COG0045	succinate-CoA ligase (ADP-forming) activity
J4N43_19675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N43_19675	COG1042	CoA-binding domain protein
J4N43_19680	COG0583	DNA-binding transcription factor activity
J4N43_19695	COG3447	MASE1 domain protein
J4N43_19695	COG5002	protein histidine kinase activity
J4N43_19695	COG5001	Diguanylate cyclase
J4N43_19700	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
J4N43_19705	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
J4N43_19710	COG1984	allophanate hydrolase subunit 2
J4N43_19720	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
J4N43_19725	COG4181	ATPase activity
J4N43_19735	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J4N43_19775	COG4533	DNA binding
J4N43_19785	COG2050	protein possibly involved in aromatic compounds catabolism
J4N43_19800	COG2067	long-chain fatty acid transport protein
J4N43_19805	COG2267	carboxylic ester hydrolase activity
J4N43_19825	COG0861	Integral membrane protein TerC family
J4N43_19830	COG0737	Belongs to the 5'-nucleotidase family
J4N43_19835	COG3593	DNA synthesis involved in DNA repair
J4N43_19845	COG0583	DNA-binding transcription factor activity
J4N43_19850	COG2116	formate transmembrane transporter activity
J4N43_19855	COG2353	YceI-like domain
J4N43_19860	COG3038	cytochrome b561
J4N43_19880	COG0513	Belongs to the DEAD box helicase family
J4N43_19895	COG0840	transmembrane signaling receptor activity
J4N43_19900	COG0546	phosphoglycolate phosphatase activity
J4N43_19915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N43_19920	COG2759	Belongs to the formate--tetrahydrofolate ligase family
J4N43_19925	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J4N43_19940	COG2207	Transcriptional regulator
J4N43_19945	COG1979	alcohol dehydrogenase
J4N43_19955	COG1126	abc transporter atp-binding protein
J4N43_19960	COG0765	amino acid transport
J4N43_19965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N43_19970	COG0765	amino acid transport
J4N43_19975	COG2199	diguanylate cyclase activity
J4N43_19975	COG2200	EAL domain
J4N43_19975	COG2203	Gaf domain
J4N43_19990	COG1609	Transcriptional regulator
J4N43_19995	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N43_19995	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N43_20000	COG1105	Belongs to the carbohydrate kinase PfkB family
J4N43_20005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N43_20005	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
J4N43_20005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N43_20035	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J4N43_20045	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J4N43_20050	COG0509	glycine decarboxylation via glycine cleavage system
J4N43_20060	COG0346	lactoylglutathione lyase activity
J4N43_20065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4N43_20070	COG0583	DNA-binding transcription factor activity
J4N43_20075	COG0697	spore germination
J4N43_20080	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J4N43_20110	COG2176	DNA-directed DNA polymerase activity
J4N43_20150	COG0242	peptide deformylase activity
J4N43_20185	COG2239	Acts as a magnesium transporter
J4N43_20205	COG0346	lactoylglutathione lyase activity
J4N43_20210	COG1902	pentaerythritol trinitrate reductase activity
J4N43_20220	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J4N43_20220	COG2755	lipolytic protein G-D-S-L family
J4N43_20230	COG5642	Protein of unknown function (DUF2384)
J4N43_20235	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
J4N43_20275	COG2076	Multidrug Resistance protein
J4N43_20295	COG2962	Rard protein
J4N43_20310	COG0835	chemotaxis
J4N43_20310	COG0784	Response regulator, receiver
J4N43_20315	COG2197	response regulator
J4N43_20325	COG3706	GGDEF domain
J4N43_20330	COG2197	response regulator
J4N43_20335	COG5001	Diguanylate cyclase
J4N43_20335	COG3300	MHYT domain
J4N43_20340	COG0784	Response regulator, receiver
J4N43_20340	COG2205	protein histidine kinase activity
J4N43_20345	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J4N43_20365	COG0456	acetyltransferase
J4N43_20365	COG1214	PFAM Peptidase M22, glycoprotease
J4N43_20375	COG3069	C4-dicarboxylate transmembrane transporter activity
J4N43_20400	COG3111	PFAM Bacterial OB fold (BOF) protein
J4N43_20405	COG1597	lipid kinase activity
J4N43_20410	COG0583	DNA-binding transcription factor activity
J4N43_20415	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4N43_20445	COG0714	Associated with various cellular activities
J4N43_20450	COG0641	radical SAM
J4N43_20455	COG3119	arylsulfatase activity
J4N43_20465	COG3119	arylsulfatase activity
J4N43_20470	COG0745	RESPONSE REGULATOR receiver
J4N43_20485	COG2205	protein histidine kinase activity
J4N43_20485	COG0784	Response regulator, receiver
J4N43_20485	COG2198	Histidine kinase
J4N43_20490	COG1879	ABC-type sugar transport system periplasmic component
J4N43_20495	COG1803	Methylglyoxal synthase
J4N43_20500	COG0210	DNA helicase
J4N43_20505	COG1289	transmembrane transporter activity
J4N43_20545	COG4771	TonB-dependent receptor
J4N43_20545	COG1629	transport
J4N43_20555	COG0789	Transcriptional regulator
J4N43_20560	COG4604	ABC transporter, ATP-binding protein
J4N43_20565	COG4605	iron ion homeostasis
J4N43_20570	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N43_20575	COG4607	ABC-type enterochelin transport system periplasmic component
J4N43_20590	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
J4N43_20600	COG1609	Transcriptional regulator
J4N43_20605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N43_20610	COG1879	ABC-type sugar transport system periplasmic component
J4N43_20615	COG1172	Belongs to the binding-protein-dependent transport system permease family
J4N43_20620	COG1129	ABC transporter
J4N43_20625	COG1869	D-ribose catabolic process
J4N43_20630	COG5001	Diguanylate cyclase
J4N43_20685	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J4N43_20695	COG0784	Response regulator, receiver
J4N43_20695	COG2205	protein histidine kinase activity
J4N43_20710	COG0330	HflC and HflK could
J4N43_20725	COG0517	IMP dehydrogenase activity
J4N43_20725	COG4175	Glycine betaine
J4N43_20730	COG4176	ABC-type proline glycine betaine transport system permease component
J4N43_20745	COG1012	belongs to the aldehyde dehydrogenase family
J4N43_20750	COG1309	transcriptional regulator
J4N43_20760	COG1028	Short-chain dehydrogenase reductase Sdr
J4N43_20775	COG1024	Enoyl-CoA hydratase
J4N43_20780	COG1960	acyl-CoA dehydrogenase activity
J4N43_20790	COG0183	Belongs to the thiolase family
J4N43_20800	COG1960	acyl-CoA dehydrogenase activity
J4N43_20805	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J4N43_20815	COG4770	biotin carboxylase activity
J4N43_20830	COG3264	Mechanosensitive ion channel
J4N43_20830	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J4N43_20835	COG0110	maltose O-acetyltransferase activity
J4N43_20840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N43_20845	COG1271	oxidase subunit
J4N43_20850	COG1294	oxidase, subunit
J4N43_20875	COG3527	Alpha-acetolactate decarboxylase
J4N43_20890	COG0500	methyltransferase
J4N43_20920	COG1022	Amp-dependent synthetase and ligase
J4N43_20945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J4N43_20950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N43_20950	COG1263	PTS System
J4N43_20955	COG1486	melibiose metabolic process
J4N43_20960	COG2188	Transcriptional regulator
J4N43_20965	COG1320	monovalent cation:proton antiporter activity
J4N43_20970	COG2212	antiporter activity
J4N43_20975	COG1863	multisubunit Na H antiporter MnhE subunit
J4N43_20980	COG0651	ATP synthesis coupled electron transport
J4N43_20985	COG1006	Multisubunit Na H antiporter MnhC subunit
J4N43_20990	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J4N43_20990	COG2111	Na H antiporter
J4N43_21000	COG0589	response to stress
J4N43_21005	COG4221	oxidoreductase activity
J4N43_21010	COG0583	DNA-binding transcription factor activity
J4N43_21020	COG2814	Major facilitator Superfamily
J4N43_21090	COG1522	sequence-specific DNA binding
J4N43_21125	COG0515	serine threonine protein kinase
J4N43_21150	COG3501	Rhs element vgr protein
J4N43_21190	COG0739	heme binding
J4N43_21215	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N43_21220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N43_21230	COG2207	Transcriptional regulator
J4N43_21250	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N43_21255	COG3537	Alpha-1,2-mannosidase
J4N43_21260	COG3537	Alpha-1,2-mannosidase
J4N43_21270	COG3537	Alpha-1,2-mannosidase
J4N43_21295	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J4N43_21295	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J4N43_21310	COG4989	oxidoreductase activity
J4N43_21325	COG0038	chloride channel
J4N43_21360	COG2897	thiosulfate sulfurtransferase activity
J4N43_21370	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J4N43_21375	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J4N43_21385	COG2814	Major facilitator Superfamily
J4N43_21390	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4N43_21400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N43_21410	COG0840	transmembrane signaling receptor activity
J4N43_21430	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4N43_21445	COG2197	response regulator
J4N43_21450	COG3850	Histidine kinase
J4N43_21455	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J4N43_21465	COG0243	molybdopterin cofactor binding
J4N43_21475	COG3005	denitrification pathway
J4N43_21485	COG3243	poly(R)-hydroxyalkanoic acid synthase
J4N43_21495	COG0183	Belongs to the thiolase family
J4N43_21505	COG1280	lysine exporter protein (LysE YggA)
J4N43_21515	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N43_21520	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N43_21570	COG1846	Transcriptional regulator
J4N43_21575	COG0784	Response regulator, receiver
J4N43_21575	COG2205	protein histidine kinase activity
J4N43_21580	COG1879	ABC-type sugar transport system periplasmic component
J4N43_21585	COG2827	Endonuclease containing a URI domain
J4N43_21590	COG3132	Protein of unknown function, DUF480
J4N43_21610	COG5002	protein histidine kinase activity
J4N43_21610	COG2205	protein histidine kinase activity
J4N43_21610	COG0784	Response regulator, receiver
J4N43_21635	COG0583	DNA-binding transcription factor activity
J4N43_21645	COG0531	amino acid
J4N43_21660	COG2205	protein histidine kinase activity
J4N43_21665	COG0745	RESPONSE REGULATOR receiver
J4N43_21690	COG1566	PFAM secretion protein HlyD family protein
J4N43_21695	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J4N43_21700	COG2239	Acts as a magnesium transporter
J4N43_21705	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J4N43_21710	COG0402	S-adenosylhomocysteine deaminase activity
J4N43_21715	COG1418	mRNA catabolic process
J4N43_21725	COG2814	Major facilitator Superfamily
J4N43_21735	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J4N43_21755	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4N43_21770	COG0745	RESPONSE REGULATOR receiver
J4N43_21775	COG2205	protein histidine kinase activity
J4N43_21785	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J4N43_21790	COG2194	sulfuric ester hydrolase activity
J4N43_21810	COG4667	esterase of the alpha-beta hydrolase superfamily
J4N43_21815	COG1741	Belongs to the pirin family
J4N43_21820	COG1278	Cold shock
J4N43_21835	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J4N43_21840	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J4N43_21840	COG0678	peroxiredoxin activity
J4N43_21850	COG1686	Belongs to the peptidase S11 family
J4N43_21855	COG0625	glutathione transferase activity
J4N43_21860	COG1621	beta-fructofuranosidase activity
J4N43_21865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N43_21870	COG1263	PTS System
J4N43_21870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N43_21895	COG1028	Short-chain dehydrogenase reductase Sdr
J4N43_21910	COG3746	phosphate-selective porin O and P
J4N43_21930	COG0583	DNA-binding transcription factor activity
J4N43_21935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4N43_21935	COG2207	Transcriptional regulator
J4N43_21940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N43_21975	COG0513	Belongs to the DEAD box helicase family
J4N43_21985	COG0583	DNA-binding transcription factor activity
J4N43_22000	COG1902	pentaerythritol trinitrate reductase activity
J4N43_22005	COG1063	alcohol dehydrogenase
J4N43_22015	COG1028	Short-chain dehydrogenase reductase Sdr
J4N43_22025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N43_22030	COG0006	proline dipeptidase activity
J4N43_22035	COG3608	succinylglutamate desuccinylase aspartoacylase
J4N43_22040	COG1522	sequence-specific DNA binding
J4N43_22045	COG1012	belongs to the aldehyde dehydrogenase family
J4N43_22050	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J4N43_22055	COG3122	Protein conserved in bacteria
J4N43_22070	COG0583	DNA-binding transcription factor activity
J4N43_22075	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J4N43_22080	COG0252	asparaginase activity
J4N43_22085	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
J4N43_22100	COG2197	response regulator
J4N43_22105	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J4N43_22130	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N43_22160	COG3842	ATPase activity
J4N43_22180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N43_22210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4N43_22215	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J4N43_22245	COG0583	DNA-binding transcription factor activity
J4N43_22255	COG4948	Mandelate Racemase Muconate Lactonizing
J4N43_22285	COG1342	Belongs to the UPF0251 family
J4N43_22290	COG4176	ABC-type proline glycine betaine transport system permease component
J4N43_22295	COG3448	diguanylate cyclase activity
J4N43_22295	COG4175	Glycine betaine
J4N43_22300	COG3015	lipoprotein NlpE involved in copper resistance
J4N43_22305	COG3713	MltA-interacting MipA family protein
J4N43_22320	COG0583	DNA-binding transcription factor activity
J4N43_22345	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
J4N43_22355	COG1335	isochorismatase
J4N43_22370	COG1349	DNA-binding transcription factor activity
J4N43_22375	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N43_22375	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N43_22380	COG2070	2-Nitropropane dioxygenase
J4N43_22385	COG0531	amino acid
J4N43_22390	COG4302	ethanolamine ammonia-lyase activity
J4N43_22395	COG4303	Ethanolamine ammonia lyase large subunit
J4N43_22405	COG1309	transcriptional regulator
J4N43_22425	COG1280	lysine exporter protein (LysE YggA)
J4N43_22440	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J4N43_22445	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4N43_22460	COG1304	FMN binding
J4N43_22485	COG1256	bacterial-type flagellum assembly
J4N43_22485	COG4786	Flagellar basal body rod
J4N43_22495	COG1706	bacterial-type flagellum-dependent cell motility
J4N43_22500	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J4N43_22505	COG4786	Flagellar basal body rod
J4N43_22510	COG4787	bacterial-type flagellum-dependent cell motility
J4N43_22525	COG1558	bacterial-type flagellum-dependent cell motility
J4N43_22530	COG1815	bacterial-type flagellum-dependent cell motility
J4N43_22550	COG0741	lytic transglycosylase activity
J4N43_22550	COG1388	LysM domain
J4N43_22555	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J4N43_22575	COG1760	l-serine dehydratase
J4N43_22590	COG0583	DNA-binding transcription factor activity
J4N43_22600	COG2866	Carboxypeptidase
J4N43_22605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4N43_22615	COG2990	Protein conserved in bacteria
J4N43_22640	COG3842	ATPase activity
J4N43_22645	COG1840	ABC-type Fe3 transport system, periplasmic component
J4N43_22655	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J4N43_22665	COG1609	Transcriptional regulator
J4N43_22695	COG3240	lipase activity
J4N43_22700	COG1309	transcriptional regulator
J4N43_22715	COG0577	efflux transmembrane transporter activity
J4N43_22715	COG1136	(ABC) transporter
J4N43_22720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N43_22725	COG2067	long-chain fatty acid transport protein
J4N43_22735	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
J4N43_22750	COG1011	Hydrolase
J4N43_22775	COG0110	maltose O-acetyltransferase activity
J4N43_22780	COG1765	OsmC-like protein
J4N43_22785	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N43_22785	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N43_22800	COG3046	protein related to deoxyribodipyrimidine photolyase
J4N43_22805	COG0415	Belongs to the DNA photolyase family
J4N43_22810	COG3706	GGDEF domain
J4N43_22825	COG3706	GGDEF domain
J4N43_22840	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4N43_22860	COG3033	Beta-eliminating lyase
J4N43_22870	COG1271	oxidase subunit
J4N43_22875	COG1294	oxidase, subunit
J4N43_22895	COG0579	oxidoreductase
J4N43_22915	COG3706	GGDEF domain
J4N43_22945	COG0583	DNA-binding transcription factor activity
J4N43_22965	COG0189	ligase activity
J4N43_22970	COG0189	ligase activity
J4N43_22970	COG4067	protein conserved in archaea
J4N43_22980	COG1166	arginine decarboxylase activity
J4N43_22985	COG0010	Belongs to the arginase family
J4N43_22990	COG2814	Major facilitator Superfamily
J4N43_22995	COG1770	oligopeptidase
J4N43_23010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J4N43_23015	COG1121	(ABC) transporter
J4N43_23020	COG0803	Belongs to the bacterial solute-binding protein 9 family
J4N43_23065	COG0848	biopolymer transport protein
J4N43_23070	COG0811	peptide transport
J4N43_23075	COG0811	peptide transport
J4N43_23095	COG0745	RESPONSE REGULATOR receiver
J4N43_23100	COG0584	glycerophosphoryl diester phosphodiesterase
J4N43_23110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J4N43_23170	COG1901	pseudouridine methyltransferase
J4N43_23175	COG0312	modulator of DNA gyrase
J4N43_23180	COG0312	modulator of DNA gyrase
J4N43_23185	COG0351	phosphomethylpyrimidine kinase
J4N43_23190	COG1116	anion transmembrane transporter activity
J4N43_23195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J4N43_23200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J4N43_23205	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J4N43_23225	COG0243	molybdopterin cofactor binding
J4N43_23230	COG3005	denitrification pathway
J4N43_23235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N43_23240	COG1028	Short-chain dehydrogenase reductase Sdr
J4N43_23255	COG0456	acetyltransferase
J4N43_23275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N43_23280	COG1929	Belongs to the glycerate kinase type-1 family
J4N43_23285	COG2610	gluconate transmembrane transporter activity
J4N43_23290	COG3835	regulator
J4N43_23350	COG3047	cAMP biosynthetic process
J4N43_23355	COG1357	PFAM Pentapeptide repeats (8 copies)
J4N43_23385	COG2375	cellular response to nickel ion
J4N43_23390	COG0583	DNA-binding transcription factor activity
J4N43_23395	COG2162	N-hydroxyarylamine O-acetyltransferase activity
J4N43_23400	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
J4N43_23415	COG2199	diguanylate cyclase activity
J4N43_23425	COG0561	phosphatase activity
J4N43_23430	COG0583	DNA-binding transcription factor activity
J4N43_23445	COG0564	pseudouridine synthase activity
J4N43_23450	COG0534	Mate efflux family protein
J4N43_23465	COG3123	guanosine phosphorylase activity
J4N43_23480	COG0596	Alpha beta hydrolase
J4N43_23505	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4N43_23515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J4N43_23520	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J4N43_23520	COG2169	Transcriptional regulator
J4N43_23530	COG2259	Doxx family
J4N43_23535	COG1741	Belongs to the pirin family
J4N43_23555	COG0363	glucosamine-6-phosphate deaminase activity
J4N43_23565	COG0786	glutamate:sodium symporter activity
J4N43_23570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N43_23575	COG1131	(ABC) transporter
J4N43_23585	COG0786	glutamate:sodium symporter activity
J4N43_23605	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J4N43_23615	COG3279	Response regulator of the LytR AlgR family
J4N43_23620	COG3275	phosphorelay sensor kinase activity
J4N43_23640	COG1136	(ABC) transporter
J4N43_23650	COG0772	Belongs to the SEDS family
J4N43_23675	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J4N43_23675	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
J4N43_23685	COG0444	Belongs to the ABC transporter superfamily
J4N43_23690	COG4608	Belongs to the ABC transporter superfamily
J4N43_23705	COG1192	Involved in chromosome partitioning
J4N43_23805	COG3549	Plasmid maintenance system killer
J4N43_23810	COG3093	addiction module antidote protein HigA
J4N43_23905	COG1629	transport
J4N43_23905	COG4774	siderophore transport
J4N43_23910	COG2382	esterase
J4N43_23940	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J4N43_23945	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
J4N43_23950	COG0247	lactate metabolic process
J4N43_23975	COG1278	Cold shock
J4N43_23990	COG1609	Transcriptional regulator
J4N43_24000	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N43_24005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4N43_24010	COG1085	galactose-1-phosphate uridylyltransferase
J4N43_24025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N43_24050	COG4680	protein conserved in bacteria
J4N43_24055	COG5499	transcription regulator containing HTH domain
J4N43_24105	COG2161	toxin-antitoxin pair type II binding
J4N43_24110	COG4115	mRNA cleavage
J4N43_24225	COG1278	Cold shock
J4N43_24325	COG0776	regulation of translation
J4N43_24355	COG0629	single-stranded DNA binding