locus-tag	class	description
J4N42_00010	COG0592	DNA-directed DNA polymerase activity
J4N42_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J4N42_00020	COG0187	DNA topoisomerase II activity
J4N42_00030	COG3977	Valine--pyruvate aminotransferase
J4N42_00035	COG0751	glycine-tRNA ligase activity
J4N42_00040	COG0752	glycyl-tRNA synthetase alpha subunit
J4N42_00045	COG2119	membrane
J4N42_00055	COG0425	Belongs to the sulfur carrier protein TusA family
J4N42_00070	COG0604	alcohol dehydrogenase
J4N42_00080	COG0129	dihydroxy-acid dehydratase activity
J4N42_00085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J4N42_00090	COG3978	acetolactate synthase activity
J4N42_00100	COG0606	chelatase, subunit chli
J4N42_00110	COG0204	Acyl-transferase
J4N42_00115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4N42_00120	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J4N42_00130	COG3084	Protein conserved in bacteria
J4N42_00140	COG4326	sporulation control protein
J4N42_00145	COG1272	protein, Hemolysin III
J4N42_00155	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4N42_00160	COG0569	domain protein
J4N42_00165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J4N42_00165	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J4N42_00180	COG1652	LysM domain
J4N42_00185	COG0758	DNA mediated transformation
J4N42_00200	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J4N42_00205	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J4N42_00210	COG0009	L-threonylcarbamoyladenylate synthase
J4N42_00215	COG0408	coproporphyrinogen oxidase activity
J4N42_00220	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J4N42_00230	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J4N42_00270	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J4N42_00285	COG3852	Histidine kinase
J4N42_00295	COG0174	glutamine synthetase
J4N42_00300	COG1217	gtp-binding protein TYPA
J4N42_00310	COG1295	ribonuclease BN
J4N42_00315	COG1490	D-aminoacyl-tRNA deacylase activity
J4N42_00320	COG0456	acetyltransferase
J4N42_00335	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
J4N42_00340	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J4N42_00345	COG3031	protein transport across the cell outer membrane
J4N42_00355	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4N42_00360	COG1459	type II secretion system
J4N42_00365	COG2165	general secretion pathway protein
J4N42_00370	COG2165	general secretion pathway protein
J4N42_00375	COG2165	general secretion pathway protein
J4N42_00380	COG4795	General secretion pathway protein
J4N42_00385	COG3156	type II secretion system protein K
J4N42_00390	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
J4N42_00395	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
J4N42_00405	COG1218	3'(2'),5'-bisphosphate nucleotidase
J4N42_00410	COG0494	nUDIX hydrolase
J4N42_00425	COG0596	Alpha beta hydrolase
J4N42_00435	COG2183	response to ionizing radiation
J4N42_00440	COG4067	protein conserved in archaea
J4N42_00440	COG0189	ligase activity
J4N42_00465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4N42_00520	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J4N42_00525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4N42_00530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J4N42_00535	COG1758	RNA polymerase activity
J4N42_00540	COG0194	GDP metabolic process
J4N42_00545	COG2252	PERMEase
J4N42_00565	COG1561	YicC-like family, N-terminal region
J4N42_00570	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J4N42_00575	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J4N42_00580	COG1560	Kdo2-lipid A biosynthetic process
J4N42_00585	COG1309	transcriptional regulator
J4N42_00590	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J4N42_00600	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J4N42_00605	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J4N42_00630	COG0859	PFAM glycosyl transferase family 9
J4N42_00635	COG1519	Transferase
J4N42_00640	COG3642	lipopolysaccharide core region biosynthetic process
J4N42_00650	COG0859	PFAM glycosyl transferase family 9
J4N42_00655	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
J4N42_00665	COG1560	Kdo2-lipid A biosynthetic process
J4N42_00670	COG0297	glycogen (starch) synthase activity
J4N42_00730	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J4N42_00735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4N42_00745	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J4N42_00765	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
J4N42_00775	COG0459	protein refolding
J4N42_00785	COG1119	ATPase activity
J4N42_00795	COG1494	fructose-1,6-bisphosphatase
J4N42_00800	COG3074	FtsZ-dependent cytokinesis
J4N42_00805	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J4N42_00810	COG0527	aspartate kinase activity
J4N42_00810	COG0460	homoserine dehydrogenase
J4N42_00815	COG0626	cystathionine gamma-synthase activity
J4N42_00820	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
J4N42_00825	COG0281	malic enzyme
J4N42_00835	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J4N42_00840	COG1609	Transcriptional regulator
J4N42_00850	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
J4N42_00865	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
J4N42_00870	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
J4N42_00875	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J4N42_00880	COG1053	succinate dehydrogenase
J4N42_00885	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
J4N42_00890	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N42_00935	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J4N42_00975	COG0438	transferase activity, transferring glycosyl groups
J4N42_00985	COG0438	transferase activity, transferring glycosyl groups
J4N42_00990	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J4N42_01000	COG3273	potassium ion transport
J4N42_01000	COG0471	metal ion transport
J4N42_01005	COG0175	sulfate reduction
J4N42_01010	COG0529	Catalyzes the synthesis of activated sulfate
J4N42_01015	COG2895	sulfate adenylyltransferase (ATP) activity
J4N42_01020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J4N42_01035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4N42_01050	COG1045	serine acetyltransferase
J4N42_01055	COG1695	Transcriptional regulator
J4N42_01060	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
J4N42_01070	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J4N42_01075	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J4N42_01080	COG0137	argininosuccinate synthase activity
J4N42_01085	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J4N42_01085	COG0165	Argininosuccinate lyase
J4N42_01100	COG0251	oxidation-reduction process
J4N42_01105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N42_01110	COG0678	peroxiredoxin activity
J4N42_01110	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J4N42_01120	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J4N42_01155	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J4N42_01165	COG0338	D12 class N6 adenine-specific DNA methyltransferase
J4N42_01170	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J4N42_01175	COG0546	phosphoglycolate phosphatase activity
J4N42_01180	COG0180	Tryptophanyl-tRNA synthetase
J4N42_01185	COG2755	lipolytic protein G-D-S-L family
J4N42_01185	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J4N42_01195	COG0512	Glutamine amidotransferase of anthranilate synthase
J4N42_01200	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J4N42_01210	COG1012	belongs to the aldehyde dehydrogenase family
J4N42_01220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N42_01225	COG3954	Phosphoribulokinase
J4N42_01230	COG3089	Belongs to the UPF0270 family
J4N42_01235	COG0429	hydrolase of the alpha beta-hydrolase fold
J4N42_01245	COG0488	(ABC) transporter
J4N42_01250	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N42_01265	COG1047	Peptidyl-prolyl cis-trans
J4N42_01270	COG1446	asparaginase
J4N42_01275	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J4N42_01280	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
J4N42_01285	COG0557	exoribonuclease II activity
J4N42_01290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4N42_01295	COG0051	transcription antitermination factor activity, RNA binding
J4N42_01300	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J4N42_01305	COG0088	Forms part of the polypeptide exit tunnel
J4N42_01315	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J4N42_01320	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J4N42_01325	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J4N42_01335	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J4N42_01355	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J4N42_01365	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J4N42_01370	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J4N42_01390	COG1841	ribosomal large subunit assembly
J4N42_01395	COG0200	Binds to the 23S rRNA
J4N42_01400	COG0201	protein transport
J4N42_01405	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J4N42_01410	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J4N42_01415	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J4N42_01425	COG0202	RNA polymerase activity
J4N42_01430	COG0203	ribosomal protein L17
J4N42_01440	COG0545	Peptidyl-prolyl cis-trans isomerase
J4N42_01455	COG2153	protein acetylation
J4N42_01465	COG0737	Belongs to the 5'-nucleotidase family
J4N42_01470	COG0175	sulfate reduction
J4N42_01475	COG2895	sulfate adenylyltransferase (ATP) activity
J4N42_01480	COG0471	metal ion transport
J4N42_01480	COG3273	potassium ion transport
J4N42_01485	COG0529	Catalyzes the synthesis of activated sulfate
J4N42_01520	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
J4N42_01530	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N42_01535	COG0729	surface antigen
J4N42_01545	COG2105	PFAM AIG2 family protein
J4N42_01555	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J4N42_01560	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
J4N42_01565	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J4N42_01570	COG0163	prenyltransferase activity
J4N42_01580	COG1178	ABC-type Fe3 transport system permease component
J4N42_01585	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
J4N42_01590	COG3028	Belongs to the UPF0307 family
J4N42_01595	COG0312	modulator of DNA gyrase
J4N42_01600	COG2239	Acts as a magnesium transporter
J4N42_01605	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N42_01610	COG1660	Displays ATPase and GTPase activities
J4N42_01615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N42_01620	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J4N42_01630	COG1137	ATPase activity
J4N42_01635	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J4N42_01645	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
J4N42_01660	COG1127	ABC transporter
J4N42_01665	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J4N42_01670	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J4N42_01675	COG2854	intermembrane phospholipid transfer
J4N42_01685	COG5007	Belongs to the BolA IbaG family
J4N42_01690	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J4N42_01695	COG0204	Acyl-transferase
J4N42_01750	COG0741	lytic transglycosylase activity
J4N42_01755	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
J4N42_01770	COG2066	Belongs to the glutaminase family
J4N42_01775	COG0527	aspartate kinase activity
J4N42_01780	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J4N42_01790	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J4N42_01805	COG0629	single-stranded DNA binding
J4N42_01810	COG2200	EAL domain
J4N42_01810	COG2199	diguanylate cyclase activity
J4N42_01835	COG3409	Peptidoglycan-binding domain 1 protein
J4N42_01835	COG3267	Type II secretory pathway component ExeA
J4N42_01845	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4N42_01850	COG1459	type II secretion system
J4N42_01860	COG2165	general secretion pathway protein
J4N42_01895	COG1077	Cell shape determining protein MreB Mrl
J4N42_01900	COG1792	Involved in formation and maintenance of cell shape
J4N42_01905	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
J4N42_01910	COG0424	maF-like protein
J4N42_01925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J4N42_01930	COG0312	modulator of DNA gyrase
J4N42_01985	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J4N42_02040	COG0191	fructose-bisphosphate aldolase activity
J4N42_02045	COG0668	transmembrane transport
J4N42_02070	COG3706	GGDEF domain
J4N42_02080	COG0469	pyruvate kinase activity
J4N42_02085	COG1349	DNA-binding transcription factor activity
J4N42_02090	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J4N42_02095	COG0840	transmembrane signaling receptor activity
J4N42_02100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N42_02105	COG3722	fumarate hydratase activity
J4N42_02115	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N42_02115	COG2213	PTS system mannitol-specific
J4N42_02140	COG1610	YqeY-like protein
J4N42_02145	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J4N42_02150	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J4N42_02160	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J4N42_02165	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J4N42_02170	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J4N42_02175	COG1968	undecaprenyl-diphosphatase activity
J4N42_02180	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J4N42_02185	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J4N42_02190	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J4N42_02195	COG0585	pseudouridine synthase activity
J4N42_02210	COG4942	peptidase
J4N42_02210	COG1388	LysM domain
J4N42_02215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J4N42_02220	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J4N42_02225	COG1546	Belongs to the CinA family
J4N42_02235	COG2137	regulation of response to DNA damage stimulus
J4N42_02245	COG0527	aspartate kinase activity
J4N42_02295	COG3630	sodium ion export across plasma membrane
J4N42_02300	COG0511	ligase activity, forming carbon-carbon bonds
J4N42_02300	COG5016	pyruvate
J4N42_02305	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
J4N42_02315	COG1238	metal cluster binding
J4N42_02320	COG0612	Peptidase, M16
J4N42_02325	COG2918	glutathione biosynthetic process
J4N42_02335	COG1854	S-ribosylhomocysteine lyase activity
J4N42_02340	COG4536	flavin adenine dinucleotide binding
J4N42_02345	COG4137	Cytochrome C assembly protein
J4N42_02350	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J4N42_02365	COG0336	Belongs to the RNA methyltransferase TrmD family
J4N42_02380	COG3267	Type II secretory pathway component ExeA
J4N42_02380	COG3409	Peptidoglycan-binding domain 1 protein
J4N42_02390	COG4991	sh3 domain protein
J4N42_02395	COG0306	phosphate transporter
J4N42_02400	COG1392	Phosphate transport regulator
J4N42_02405	COG3025	triphosphatase activity
J4N42_02410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N42_02420	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J4N42_02425	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J4N42_02425	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J4N42_02430	COG1538	Outer membrane efflux protein
J4N42_02435	COG0494	nUDIX hydrolase
J4N42_02440	COG3151	Protein conserved in bacteria
J4N42_02450	COG3150	esterase
J4N42_02465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4N42_02470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4N42_02475	COG3105	Protein conserved in bacteria
J4N42_02480	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J4N42_02490	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J4N42_02495	COG0723	plastoquinol--plastocyanin reductase activity
J4N42_02500	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J4N42_02505	COG2857	Cytochrome c1
J4N42_02510	COG0625	glutathione transferase activity
J4N42_02515	COG2969	positive regulation of protein catabolic process
J4N42_02520	COG2823	Periplasmic or secreted lipoprotein
J4N42_02525	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J4N42_02530	COG0792	nuclease activity
J4N42_02535	COG3107	peptidoglycan biosynthetic process
J4N42_02540	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J4N42_02550	COG0275	rRNA processing
J4N42_02555	COG3116	cell division
J4N42_02560	COG0768	penicillin binding
J4N42_02565	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J4N42_02570	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J4N42_02585	COG0772	Belongs to the SEDS family
J4N42_02590	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J4N42_02600	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J4N42_02605	COG0849	cell division
J4N42_02610	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J4N42_02615	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J4N42_02630	COG0494	nUDIX hydrolase
J4N42_02635	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J4N42_02640	COG0505	Belongs to the CarA family
J4N42_02645	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J4N42_02650	COG0730	response to heat
J4N42_02655	COG0583	DNA-binding transcription factor activity
J4N42_02660	COG2860	membrane
J4N42_02665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4N42_02680	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J4N42_02705	COG0826	peptidase U32
J4N42_02710	COG0826	peptidase U32
J4N42_02720	COG3154	lipid carrier protein
J4N42_02725	COG3153	acetyltransferase
J4N42_02735	COG0456	acetyltransferase
J4N42_02750	COG0840	transmembrane signaling receptor activity
J4N42_02755	COG0513	Belongs to the DEAD box helicase family
J4N42_02775	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J4N42_02780	COG2204	response regulator
J4N42_02790	COG0667	Aldo Keto reductase
J4N42_02800	COG3066	DNA modification
J4N42_02805	COG0494	nUDIX hydrolase
J4N42_02815	COG0730	response to heat
J4N42_02820	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J4N42_02825	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J4N42_02830	COG1283	sodium-dependent phosphate transmembrane transporter activity
J4N42_02835	COG0583	DNA-binding transcription factor activity
J4N42_02840	COG0640	Transcriptional regulator
J4N42_02845	COG0268	Binds directly to 16S ribosomal RNA
J4N42_02850	COG0728	peptidoglycan biosynthetic process
J4N42_02855	COG0196	riboflavin kinase activity
J4N42_02865	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
J4N42_02870	COG1047	Peptidyl-prolyl cis-trans
J4N42_02875	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J4N42_02880	COG1966	Carbon starvation protein
J4N42_02890	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
J4N42_02895	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
J4N42_02905	COG3279	Response regulator of the LytR AlgR family
J4N42_02910	COG3275	phosphorelay sensor kinase activity
J4N42_02915	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4N42_02920	COG0287	Prephenate dehydrogenase
J4N42_02920	COG1605	Chorismate mutase
J4N42_02925	COG0739	heme binding
J4N42_02935	COG0488	(ABC) transporter
J4N42_02945	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
J4N42_02950	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
J4N42_02955	COG5001	Diguanylate cyclase
J4N42_02960	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J4N42_02965	COG0077	Prephenate dehydratase
J4N42_02965	COG1605	Chorismate mutase
J4N42_02970	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J4N42_02975	COG0741	lytic transglycosylase activity
J4N42_02980	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N42_02985	COG0564	pseudouridine synthase activity
J4N42_02990	COG1496	oxidoreductase activity
J4N42_02995	COG0542	response to heat
J4N42_03035	COG0483	inositol monophosphate 1-phosphatase activity
J4N42_03040	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
J4N42_03055	COG0822	iron-sulfur transferase activity
J4N42_03075	COG0633	Ferredoxin
J4N42_03080	COG2975	iron-sulfur cluster assembly
J4N42_03085	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J4N42_03110	COG0124	histidyl-tRNA synthetase
J4N42_03115	COG2976	Protein conserved in bacteria
J4N42_03120	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N42_03125	COG1160	GTP binding
J4N42_03145	COG0516	GMP reductase activity
J4N42_03145	COG0517	IMP dehydrogenase activity
J4N42_03160	COG1584	GPR1 FUN34 yaaH family protein
J4N42_03165	COG1115	amino acid carrier protein
J4N42_03175	COG0583	DNA-binding transcription factor activity
J4N42_03225	COG1253	flavin adenine dinucleotide binding
J4N42_03230	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J4N42_03240	COG0204	Acyl-transferase
J4N42_03295	COG2867	negative regulation of translational initiation
J4N42_03300	COG2914	Belongs to the UPF0125 (RnfH) family
J4N42_03310	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N42_03315	COG0497	DNA recombination
J4N42_03320	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J4N42_03330	COG1301	dicarboxylic acid transport
J4N42_03340	COG0484	heat shock protein binding
J4N42_03375	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J4N42_03390	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
J4N42_03395	COG0047	phosphoribosylformylglycinamidine synthase activity
J4N42_03395	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J4N42_03425	COG1720	tRNA m6t6A37 methyltransferase activity
J4N42_03440	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J4N42_03455	COG1671	Belongs to the UPF0178 family
J4N42_03465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N42_03485	COG0564	pseudouridine synthase activity
J4N42_03495	COG0142	geranyltranstransferase activity
J4N42_03500	COG1722	exodeoxyribonuclease VII activity
J4N42_03505	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J4N42_03515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4N42_03515	COG0301	tRNA thio-modification
J4N42_03520	COG0583	DNA-binding transcription factor activity
J4N42_03530	COG2363	Small membrane protein
J4N42_03540	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4N42_03545	COG1611	Belongs to the LOG family
J4N42_03560	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J4N42_03560	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J4N42_03570	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
J4N42_03575	COG1464	Belongs to the NlpA lipoprotein family
J4N42_03580	COG2011	ABC-type metal ion transport system permease component
J4N42_03585	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J4N42_03590	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J4N42_03600	COG1609	Transcriptional regulator
J4N42_03605	COG1263	PTS System
J4N42_03605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N42_03610	COG0366	Alpha amylase catalytic
J4N42_03640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N42_03670	COG0714	Associated with various cellular activities
J4N42_03685	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J4N42_03695	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J4N42_03705	COG2921	Belongs to the UPF0250 family
J4N42_03710	COG1686	Belongs to the peptidase S11 family
J4N42_03715	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J4N42_03720	COG0772	Belongs to the SEDS family
J4N42_03725	COG0768	penicillin binding
J4N42_03730	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J4N42_03735	COG0799	negative regulation of ribosome biogenesis
J4N42_03740	COG1466	dna polymerase III delta subunit
J4N42_03745	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
J4N42_03750	COG0495	leucyl-tRNA aminoacylation
J4N42_03755	COG2888	peptidyl-tyrosine sulfation
J4N42_03760	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J4N42_03765	COG4535	Mg2 and Co2 transporter CorC
J4N42_03770	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J4N42_03775	COG1702	phosphate starvation-inducible protein PhoH
J4N42_03780	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J4N42_03785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N42_03790	COG2190	(PTS) system
J4N42_03795	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J4N42_03800	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N42_03805	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J4N42_03810	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
J4N42_03815	COG3115	cell septum assembly
J4N42_03820	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J4N42_03845	COG0330	HflC and HflK could
J4N42_03850	COG3118	belongs to the thioredoxin family
J4N42_03855	COG0300	oxidoreductase activity
J4N42_03860	COG1090	epimerase
J4N42_03885	COG0622	Phosphoesterase
J4N42_03905	COG3710	Transcriptional regulator
J4N42_03910	COG0326	Molecular chaperone. Has ATPase activity
J4N42_03920	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J4N42_03925	COG3104	oligopeptide transport
J4N42_03935	COG0367	asparagine synthase
J4N42_03940	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J4N42_03940	COG4651	solute:proton antiporter activity
J4N42_03945	COG1846	Transcriptional regulator
J4N42_03945	COG1940	carbohydrate kinase activity
J4N42_03950	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J4N42_03955	COG1263	PTS System
J4N42_03955	COG2190	(PTS) system
J4N42_03955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N42_03960	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J4N42_03965	COG0735	belongs to the Fur family
J4N42_03975	COG0716	FMN binding
J4N42_03985	COG0596	Alpha beta hydrolase
J4N42_03990	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
J4N42_03995	COG0033	Phosphoglucomutase
J4N42_04005	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J4N42_04020	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
J4N42_04025	COG1053	succinate dehydrogenase
J4N42_04035	COG0567	Dehydrogenase, E1 component
J4N42_04040	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4N42_04055	COG2056	Na+-H+ antiporter family
J4N42_04075	COG0346	lactoylglutathione lyase activity
J4N42_04080	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J4N42_04085	COG4660	Part of a membrane complex involved in electron transport
J4N42_04090	COG4659	FMN binding
J4N42_04095	COG4658	electron transport chain
J4N42_04100	COG4656	Part of a membrane complex involved in electron transport
J4N42_04105	COG2878	Part of a membrane complex involved in electron transport
J4N42_04110	COG4657	Part of a membrane complex involved in electron transport
J4N42_04120	COG0556	nucleotide-excision repair
J4N42_04125	COG2204	response regulator
J4N42_04130	COG2198	Histidine kinase
J4N42_04135	COG0391	Required for morphogenesis under gluconeogenic growth conditions
J4N42_04140	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J4N42_04145	COG0521	Mo-molybdopterin cofactor biosynthetic process
J4N42_04155	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J4N42_04160	COG0314	molybdopterin synthase activity
J4N42_04165	COG3706	GGDEF domain
J4N42_04170	COG0617	tRNA 3'-terminal CCA addition
J4N42_04170	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J4N42_04170	COG0517	IMP dehydrogenase activity
J4N42_04205	COG0489	protein tyrosine kinase activity
J4N42_04210	COG0572	uridine kinase
J4N42_04215	COG2982	Protein involved in outer membrane biogenesis
J4N42_04220	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
J4N42_04225	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J4N42_04245	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J4N42_04250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4N42_04260	COG1881	PFAM PEBP family protein
J4N42_04270	COG0123	including yeast histone deacetylase and acetoin utilization protein
J4N42_04295	COG0745	RESPONSE REGULATOR receiver
J4N42_04315	COG3083	sulfuric ester hydrolase activity
J4N42_04320	COG3082	Protein of unknown function (DUF1414)
J4N42_04325	COG3081	Nucleoid-associated protein
J4N42_04340	COG1757	Na H antiporter
J4N42_04345	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J4N42_04350	COG2165	general secretion pathway protein
J4N42_04355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N42_04360	COG2095	MarC family integral membrane protein
J4N42_04365	COG1012	belongs to the aldehyde dehydrogenase family
J4N42_04365	COG1454	alcohol dehydrogenase
J4N42_04380	COG0659	secondary active sulfate transmembrane transporter activity
J4N42_04385	COG1530	ribonuclease E activity
J4N42_04390	COG0564	pseudouridine synthase activity
J4N42_04395	COG0424	maF-like protein
J4N42_04400	COG1399	metal-binding, possibly nucleic acid-binding protein
J4N42_04405	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J4N42_04415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J4N42_04440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J4N42_04445	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J4N42_04450	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J4N42_04460	COG0084	hydrolase, TatD family'
J4N42_04465	COG1263	PTS System
J4N42_04465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N42_04485	COG4667	esterase of the alpha-beta hydrolase superfamily
J4N42_04490	COG0469	pyruvate kinase activity
J4N42_04495	COG1940	carbohydrate kinase activity
J4N42_04500	COG0784	Response regulator, receiver
J4N42_04500	COG0835	chemotaxis
J4N42_04520	COG1028	Short-chain dehydrogenase reductase Sdr
J4N42_04525	COG0616	signal peptide processing
J4N42_04550	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
J4N42_04555	COG0436	Aminotransferase
J4N42_04560	COG1169	isochorismate synthase
J4N42_04570	COG0596	Alpha beta hydrolase
J4N42_04590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N42_04590	COG2190	(PTS) system
J4N42_04590	COG1263	PTS System
J4N42_04605	COG2855	membrane
J4N42_04645	COG2983	Belongs to the UPF0260 family
J4N42_04665	COG2226	methyltransferase
J4N42_04675	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J4N42_04690	COG3139	Protein of unknown function (DUF1315)
J4N42_04695	COG0252	asparaginase activity
J4N42_04700	COG0616	signal peptide processing
J4N42_04705	COG1902	pentaerythritol trinitrate reductase activity
J4N42_04705	COG0446	pyridine nucleotide-disulphide oxidoreductase
J4N42_04710	COG0788	formyltetrahydrofolate deformylase activity
J4N42_04720	COG1199	ATP-dependent helicase activity
J4N42_04725	COG1214	PFAM Peptidase M22, glycoprotease
J4N42_04740	COG0596	Alpha beta hydrolase
J4N42_04745	COG0318	PFAM AMP-dependent synthetase and ligase
J4N42_04750	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
J4N42_04760	COG2894	cell division
J4N42_04770	COG3100	YcgL domain-containing protein
J4N42_04775	COG2951	lytic endotransglycosylase activity
J4N42_04780	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J4N42_04790	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N42_04795	COG0784	Response regulator, receiver
J4N42_04795	COG2205	protein histidine kinase activity
J4N42_04795	COG5002	protein histidine kinase activity
J4N42_04805	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
J4N42_04820	COG1653	transport
J4N42_04825	COG1175	transmembrane transport
J4N42_04835	COG3842	ATPase activity
J4N42_04845	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J4N42_04850	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J4N42_04855	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N42_04870	COG2204	response regulator
J4N42_04895	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J4N42_04900	COG0776	regulation of translation
J4N42_04905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4N42_04910	COG1555	photosystem II stabilization
J4N42_04915	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J4N42_04920	COG0539	negative regulation of cytoplasmic translation
J4N42_04930	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
J4N42_04935	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
J4N42_04975	COG4120	Belongs to the binding-protein-dependent transport system permease family
J4N42_04990	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4N42_05005	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J4N42_05015	COG3012	SEC-C Motif Domain Protein
J4N42_05020	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J4N42_05025	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4N42_05030	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J4N42_05035	COG0215	cysteine-tRNA ligase activity
J4N42_05045	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J4N42_05050	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
J4N42_05065	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J4N42_05075	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4N42_05085	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J4N42_05090	COG0297	glycogen (starch) synthase activity
J4N42_05110	COG3070	regulator of competence-specific genes
J4N42_05115	COG1609	Transcriptional regulator
J4N42_05125	COG0745	RESPONSE REGULATOR receiver
J4N42_05130	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J4N42_05135	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4N42_05140	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
J4N42_05145	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
J4N42_05150	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J4N42_05180	COG0189	ligase activity
J4N42_05180	COG4067	protein conserved in archaea
J4N42_05185	COG0500	methyltransferase
J4N42_05190	COG4106	trans-aconitate 2-methyltransferase activity
J4N42_05195	COG1801	Protein of unknown function DUF72
J4N42_05205	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J4N42_05210	COG0840	transmembrane signaling receptor activity
J4N42_05215	COG0632	four-way junction helicase activity
J4N42_05225	COG1271	oxidase subunit
J4N42_05230	COG1294	oxidase, subunit
J4N42_05235	COG4890	Cyd operon protein YbgT
J4N42_05245	COG0824	Thioesterase
J4N42_05250	COG0811	peptide transport
J4N42_05265	COG0823	Involved in the tonB-independent uptake of proteins
J4N42_05270	COG2885	chlorophyll binding
J4N42_05275	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
J4N42_05285	COG3397	chitin binding
J4N42_05300	COG0784	Response regulator, receiver
J4N42_05300	COG2205	protein histidine kinase activity
J4N42_05360	COG1104	cysteine desulfurase activity
J4N42_05385	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J4N42_05390	COG3265	gluconokinase activity
J4N42_05395	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J4N42_05395	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N42_05405	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J4N42_05410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N42_05415	COG1482	cell wall glycoprotein biosynthetic process
J4N42_05420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N42_05420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N42_05420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N42_05425	COG2207	Transcriptional regulator
J4N42_05435	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N42_05440	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N42_05460	COG5002	protein histidine kinase activity
J4N42_05460	COG3850	Histidine kinase
J4N42_05465	COG0745	RESPONSE REGULATOR receiver
J4N42_05470	COG0463	Glycosyl transferase, family 2
J4N42_05475	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
J4N42_05490	COG1960	acyl-CoA dehydrogenase activity
J4N42_05495	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J4N42_05505	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J4N42_05510	COG1979	alcohol dehydrogenase
J4N42_05515	COG1737	Transcriptional regulator
J4N42_05520	COG0076	glutamate decarboxylase activity
J4N42_05530	COG2431	L-lysine efflux transmembrane transporter activity
J4N42_05540	COG3070	regulator of competence-specific genes
J4N42_05555	COG4191	Histidine kinase
J4N42_05565	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J4N42_05575	COG1032	radical SAM domain protein
J4N42_05580	COG2203	Gaf domain
J4N42_05580	COG2199	diguanylate cyclase activity
J4N42_05580	COG2200	EAL domain
J4N42_05600	COG0583	DNA-binding transcription factor activity
J4N42_05605	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J4N42_05620	COG2350	Protein conserved in bacteria
J4N42_05650	COG1301	dicarboxylic acid transport
J4N42_05655	COG0159	tryptophan synthase activity
J4N42_05665	COG0135	phosphoribosylanthranilate isomerase activity
J4N42_05665	COG0134	indole-3-glycerol-phosphate synthase activity
J4N42_05670	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J4N42_05675	COG0512	Glutamine amidotransferase of anthranilate synthase
J4N42_05680	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J4N42_05695	COG0009	L-threonylcarbamoyladenylate synthase
J4N42_05700	COG1187	pseudouridine synthase activity
J4N42_05705	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J4N42_05710	COG4988	ABC transporter
J4N42_05715	COG0492	ferredoxin-NADP+ reductase activity
J4N42_05725	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J4N42_05740	COG2949	membrane
J4N42_05750	COG0281	malic enzyme
J4N42_05755	COG1643	Atp-dependent helicase
J4N42_05770	COG1448	Aminotransferase
J4N42_05780	COG3437	response regulator, receiver
J4N42_05780	COG2770	Histidine kinase
J4N42_05790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N42_05800	COG0017	Asparaginyl-tRNA synthetase
J4N42_05805	COG0840	transmembrane signaling receptor activity
J4N42_05810	COG0720	synthase
J4N42_05820	COG0814	amino acid
J4N42_05825	COG3300	MHYT domain
J4N42_05825	COG5001	Diguanylate cyclase
J4N42_05830	COG1760	l-serine dehydratase
J4N42_05835	COG0814	amino acid
J4N42_05850	COG2205	protein histidine kinase activity
J4N42_05850	COG0784	Response regulator, receiver
J4N42_05855	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J4N42_05870	COG3106	COG3106 Predicted ATPase
J4N42_05885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N42_05925	COG2989	Protein conserved in bacteria
J4N42_05930	COG3108	Peptidase M15
J4N42_05935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4N42_05975	COG0247	lactate metabolic process
J4N42_05975	COG0277	FAD linked oxidase domain protein
J4N42_05995	COG2986	histidine ammonia-lyase
J4N42_06005	COG0010	Belongs to the arginase family
J4N42_06010	COG1228	amidohydrolase
J4N42_06020	COG3097	Belongs to the UPF0267 family
J4N42_06030	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J4N42_06040	COG0417	DNA replication proofreading
J4N42_06045	COG2197	response regulator
J4N42_06050	COG0322	excinuclease ABC activity
J4N42_06095	COG2133	pyrroloquinoline quinone binding
J4N42_06105	COG0443	Heat shock 70 kDa protein
J4N42_06110	COG0443	Heat shock 70 kDa protein
J4N42_06155	COG1643	Atp-dependent helicase
J4N42_06185	COG0589	response to stress
J4N42_06195	COG1129	ABC transporter
J4N42_06200	COG1132	(ABC) transporter
J4N42_06215	COG3240	lipase activity
J4N42_06225	COG1131	(ABC) transporter
J4N42_06230	COG0842	Transport permease protein
J4N42_06235	COG1028	Short-chain dehydrogenase reductase Sdr
J4N42_06245	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4N42_06245	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4N42_06255	COG0384	phenazine biosynthesis protein PhzF
J4N42_06260	COG2375	cellular response to nickel ion
J4N42_06285	COG2814	Major facilitator Superfamily
J4N42_06290	COG0583	DNA-binding transcription factor activity
J4N42_06305	COG1309	transcriptional regulator
J4N42_06320	COG0534	Mate efflux family protein
J4N42_06325	COG0444	Belongs to the ABC transporter superfamily
J4N42_06335	COG0747	negative chemotaxis
J4N42_06350	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
J4N42_06365	COG1280	lysine exporter protein (LysE YggA)
J4N42_06370	COG0784	Response regulator, receiver
J4N42_06370	COG3437	response regulator, receiver
J4N42_06375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N42_06375	COG4191	Histidine kinase
J4N42_06385	COG1115	amino acid carrier protein
J4N42_06410	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4N42_06425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N42_06430	COG1609	Transcriptional regulator
J4N42_06445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N42_06450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4N42_06450	COG2207	Transcriptional regulator
J4N42_06465	COG0840	transmembrane signaling receptor activity
J4N42_06470	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
J4N42_06480	COG0583	DNA-binding transcription factor activity
J4N42_06510	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N42_06515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N42_06540	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
J4N42_06540	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J4N42_06545	COG2815	serine threonine protein kinase
J4N42_06545	COG0515	serine threonine protein kinase
J4N42_06550	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4N42_06555	COG2200	EAL domain
J4N42_06565	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
J4N42_06575	COG0625	glutathione transferase activity
J4N42_06585	COG0584	glycerophosphoryl diester phosphodiesterase
J4N42_06600	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N42_06610	COG1349	DNA-binding transcription factor activity
J4N42_06615	COG3842	ATPase activity
J4N42_06620	COG0395	ABC-type sugar transport system, permease component
J4N42_06625	COG1175	transmembrane transport
J4N42_06640	COG0039	L-malate dehydrogenase activity
J4N42_06660	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4N42_06670	COG2116	formate transmembrane transporter activity
J4N42_06675	COG1648	precorrin-2 dehydrogenase activity
J4N42_06675	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J4N42_06685	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J4N42_06690	COG0183	Belongs to the thiolase family
J4N42_06700	COG2205	protein histidine kinase activity
J4N42_06700	COG0784	Response regulator, receiver
J4N42_06700	COG5002	protein histidine kinase activity
J4N42_06705	COG3437	response regulator, receiver
J4N42_06715	COG3290	protein histidine kinase activity
J4N42_06720	COG4565	transcriptional regulatory protein
J4N42_06730	COG0835	chemotaxis
J4N42_06730	COG0784	Response regulator, receiver
J4N42_06765	COG2964	Protein conserved in bacteria
J4N42_06770	COG0251	oxidation-reduction process
J4N42_06780	COG0446	pyridine nucleotide-disulphide oxidoreductase
J4N42_06795	COG0583	DNA-binding transcription factor activity
J4N42_06810	COG1451	nucleotide metabolic process
J4N42_06825	COG3063	Type IV pilus biogenesis stability protein PilW
J4N42_06830	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
J4N42_06845	COG2200	EAL domain
J4N42_06860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N42_06885	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J4N42_06895	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
J4N42_06900	COG0372	Belongs to the citrate synthase family
J4N42_06905	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J4N42_06935	COG0561	phosphatase activity
J4N42_06940	COG0602	queuosine metabolic process
J4N42_06950	COG3706	GGDEF domain
J4N42_06985	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J4N42_06995	COG1254	Belongs to the acylphosphatase family
J4N42_07000	COG2920	part of a sulfur-relay system
J4N42_07005	COG0670	Belongs to the BI1 family
J4N42_07010	COG1126	abc transporter atp-binding protein
J4N42_07015	COG0765	amino acid transport
J4N42_07020	COG4597	amino acid ABC transporter
J4N42_07025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N42_07035	COG1666	GTP binding
J4N42_07040	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4N42_07060	COG2996	Protein conserved in bacteria
J4N42_07065	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
J4N42_07065	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J4N42_07070	COG3008	intermembrane lipid transfer
J4N42_07075	COG2995	paraquat-inducible protein a
J4N42_07080	COG1132	(ABC) transporter
J4N42_07085	COG1956	GAF domain-containing protein
J4N42_07090	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
J4N42_07105	COG0308	aminopeptidase N
J4N42_07115	COG2902	Dehydrogenase
J4N42_07130	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J4N42_07130	COG0116	Belongs to the methyltransferase superfamily
J4N42_07140	COG0488	(ABC) transporter
J4N42_07155	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J4N42_07160	COG1067	ATP-dependent peptidase activity
J4N42_07165	COG3120	sequence-specific DNA binding
J4N42_07180	COG0784	Response regulator, receiver
J4N42_07180	COG2205	protein histidine kinase activity
J4N42_07195	COG3278	Belongs to the heme-copper respiratory oxidase family
J4N42_07210	COG2010	Cytochrome c
J4N42_07220	COG2217	Heavy metal translocating P-type atpase
J4N42_07235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N42_07240	COG0589	response to stress
J4N42_07270	COG3842	ATPase activity
J4N42_07280	COG1177	transmembrane transport
J4N42_07285	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J4N42_07300	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J4N42_07305	COG0004	ammonium transporteR
J4N42_07320	COG0437	4 iron, 4 sulfur cluster binding
J4N42_07325	COG0243	molybdopterin cofactor binding
J4N42_07325	COG3383	formate dehydrogenase (NAD+) activity
J4N42_07355	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J4N42_07360	COG0840	transmembrane signaling receptor activity
J4N42_07370	COG0488	(ABC) transporter
J4N42_07385	COG3852	Histidine kinase
J4N42_07390	COG2204	response regulator
J4N42_07400	COG4662	Binding-protein-dependent transport system inner membrane component
J4N42_07405	COG3842	ATPase activity
J4N42_07410	COG0746	molybdenum cofactor guanylyltransferase activity
J4N42_07415	COG0303	'Molybdopterin
J4N42_07425	COG1940	carbohydrate kinase activity
J4N42_07430	COG3148	PFAM DTW domain containing protein
J4N42_07440	COG0840	transmembrane signaling receptor activity
J4N42_07445	COG0791	NLP P60 protein
J4N42_07455	COG3001	Fructosamine kinase
J4N42_07525	COG2814	Major facilitator Superfamily
J4N42_07570	COG0307	riboflavin synthase, alpha
J4N42_07575	COG0534	Mate efflux family protein
J4N42_07580	COG1793	dna ligase
J4N42_07585	COG1366	Belongs to the anti-sigma-factor antagonist family
J4N42_07615	COG2204	response regulator
J4N42_07620	COG0438	transferase activity, transferring glycosyl groups
J4N42_07645	COG0297	glycogen (starch) synthase activity
J4N42_07655	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J4N42_07670	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
J4N42_07675	COG4139	cobalamin transport
J4N42_07700	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J4N42_07705	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J4N42_07715	COG2814	Major facilitator Superfamily
J4N42_07730	COG2925	Exonuclease
J4N42_07735	COG1380	Effector of murein hydrolase LrgA
J4N42_07740	COG1346	cytolysis
J4N42_07745	COG0295	cytidine deaminase activity
J4N42_07765	COG3409	Peptidoglycan-binding domain 1 protein
J4N42_07765	COG3501	Rhs element vgr protein
J4N42_07795	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J4N42_07810	COG0776	regulation of translation
J4N42_07855	COG0204	Acyl-transferase
J4N42_07860	COG0513	Belongs to the DEAD box helicase family
J4N42_07865	COG1454	alcohol dehydrogenase
J4N42_07875	COG1115	amino acid carrier protein
J4N42_07890	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J4N42_07900	COG2188	Transcriptional regulator
J4N42_07905	COG5640	endopeptidase activity
J4N42_07910	COG0531	amino acid
J4N42_07915	COG1901	pseudouridine methyltransferase
J4N42_07945	COG3448	diguanylate cyclase activity
J4N42_07945	COG4175	Glycine betaine
J4N42_07950	COG4176	ABC-type proline glycine betaine transport system permease component
J4N42_07960	COG0861	Integral membrane protein TerC family
J4N42_07990	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J4N42_07995	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J4N42_08000	COG0840	transmembrane signaling receptor activity
J4N42_08020	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N42_08025	COG1846	Transcriptional regulator
J4N42_08035	COG1280	lysine exporter protein (LysE YggA)
J4N42_08045	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4N42_08050	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4N42_08055	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4N42_08070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N42_08090	COG1132	(ABC) transporter
J4N42_08130	COG0019	diaminopimelate decarboxylase activity
J4N42_08160	COG1320	monovalent cation:proton antiporter activity
J4N42_08165	COG2212	antiporter activity
J4N42_08170	COG1863	multisubunit Na H antiporter MnhE subunit
J4N42_08175	COG0651	ATP synthesis coupled electron transport
J4N42_08180	COG1006	Multisubunit Na H antiporter MnhC subunit
J4N42_08185	COG2111	Na H antiporter
J4N42_08190	COG2111	Na H antiporter
J4N42_08190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J4N42_08210	COG1136	(ABC) transporter
J4N42_08215	COG0534	Mate efflux family protein
J4N42_08220	COG0702	epimerase
J4N42_08230	COG2814	Major facilitator Superfamily
J4N42_08240	COG1061	Type III restriction enzyme res subunit
J4N42_08255	COG3290	protein histidine kinase activity
J4N42_08280	COG3501	Rhs element vgr protein
J4N42_08295	COG0463	Glycosyl transferase, family 2
J4N42_08295	COG1216	Glycosyl transferase, family 2
J4N42_08300	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J4N42_08310	COG4191	Histidine kinase
J4N42_08345	COG3397	chitin binding
J4N42_08440	COG4964	Belongs to the GSP D family
J4N42_08465	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
J4N42_08470	COG2824	Alkylphosphonate utilization operon protein PhnA
J4N42_08475	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J4N42_08495	COG2205	protein histidine kinase activity
J4N42_08495	COG0784	Response regulator, receiver
J4N42_08515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N42_08515	COG4191	Histidine kinase
J4N42_08520	COG3122	Protein conserved in bacteria
J4N42_08550	COG3313	Fe-S protein
J4N42_08560	COG4134	Bacterial extracellular solute-binding protein
J4N42_08565	COG4135	transport system, permease component
J4N42_08570	COG4136	ATPase activity
J4N42_08575	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J4N42_08585	COG3047	cAMP biosynthetic process
J4N42_08585	COG2885	chlorophyll binding
J4N42_08635	COG4964	Belongs to the GSP D family
J4N42_08665	COG0116	Belongs to the methyltransferase superfamily
J4N42_08665	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J4N42_08670	COG0564	pseudouridine synthase activity
J4N42_08680	COG0733	neurotransmitter:sodium symporter activity
J4N42_08690	COG0626	cystathionine gamma-synthase activity
J4N42_08700	COG2818	Glycosylase
J4N42_08710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N42_08715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N42_08720	COG1983	PspC domain protein
J4N42_08730	COG1842	Phage shock protein A
J4N42_08735	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
J4N42_08750	COG4171	peptide transport system, permease
J4N42_08760	COG4172	Belongs to the ABC transporter superfamily
J4N42_08775	COG1227	inorganic diphosphatase activity
J4N42_08800	COG0243	molybdopterin cofactor binding
J4N42_08805	COG3005	denitrification pathway
J4N42_08810	COG4459	periplasmic nitrate reductase
J4N42_08815	COG0390	transport system, permease component
J4N42_08820	COG2116	formate transmembrane transporter activity
J4N42_08845	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J4N42_08850	COG0542	response to heat
J4N42_08860	COG1278	Cold shock
J4N42_08875	COG1187	pseudouridine synthase activity
J4N42_08880	COG0140	phosphoribosyl-ATP diphosphatase activity
J4N42_08880	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J4N42_08890	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J4N42_08895	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J4N42_08900	COG0131	Imidazoleglycerol-phosphate dehydratase
J4N42_08900	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J4N42_08905	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J4N42_08910	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J4N42_08920	COG1757	Na H antiporter
J4N42_08925	COG2916	Histone family protein nucleoid-structuring protein H-NS
J4N42_08930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N42_08940	COG0482	sulfurtransferase activity
J4N42_08950	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J4N42_08955	COG0501	Belongs to the peptidase M48B family
J4N42_08965	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J4N42_08970	COG2226	methyltransferase
J4N42_08970	COG1073	alpha beta
J4N42_08975	COG0156	8-amino-7-oxononanoate synthase activity
J4N42_08980	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J4N42_08985	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J4N42_08990	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
J4N42_08995	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J4N42_09000	COG1199	ATP-dependent helicase activity
J4N42_09005	COG0730	response to heat
J4N42_09020	COG2850	peptidyl-arginine hydroxylation
J4N42_09030	COG0840	transmembrane signaling receptor activity
J4N42_09035	COG0708	Exodeoxyribonuclease III
J4N42_09040	COG4160	amino acid transport
J4N42_09065	COG1882	Formate acetyltransferase
J4N42_09080	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J4N42_09090	COG3013	Belongs to the UPF0304 family
J4N42_09100	COG2766	serine protein kinase
J4N42_09105	COG2718	Belongs to the UPF0229 family
J4N42_09110	COG2719	SpoVR family
J4N42_09115	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J4N42_09130	COG1132	(ABC) transporter
J4N42_09135	COG2333	competence protein COMEC
J4N42_09135	COG0658	competence protein
J4N42_09145	COG4591	ABC-type transport system involved in lipoprotein release permease component
J4N42_09150	COG1136	(ABC) transporter
J4N42_09155	COG4591	ABC-type transport system involved in lipoprotein release permease component
J4N42_09165	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J4N42_09180	COG1252	NADH dehydrogenase
J4N42_09185	COG3150	esterase
J4N42_09210	COG0537	adenosine 5'-monophosphoramidase activity
J4N42_09225	COG2186	Transcriptional regulator
J4N42_09230	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J4N42_09240	COG1674	ftsk spoiiie
J4N42_09245	COG1522	sequence-specific DNA binding
J4N42_09250	COG0686	Belongs to the AlaDH PNT family
J4N42_09255	COG3092	negative regulation of chromosome organization
J4N42_09260	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J4N42_09265	COG0280	phosphate acetyltransferase
J4N42_09265	COG0857	belongs to the CobB CobQ family
J4N42_09270	COG0435	Glutathione S-transferase
J4N42_09275	COG3314	Sporulation integral membrane protein YlbJ
J4N42_09285	COG0444	Belongs to the ABC transporter superfamily
J4N42_09290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N42_09295	COG0601	transmembrane transport
J4N42_09325	COG0583	DNA-binding transcription factor activity
J4N42_09340	COG2067	long-chain fatty acid transport protein
J4N42_09370	COG0848	biopolymer transport protein
J4N42_09375	COG0811	peptide transport
J4N42_09380	COG0811	peptide transport
J4N42_09390	COG1120	ATPase activity
J4N42_09395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4N42_09400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N42_09430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4N42_09435	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J4N42_09440	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
J4N42_09470	COG0450	alkyl hydroperoxide reductase
J4N42_09480	COG3706	GGDEF domain
J4N42_09495	COG3126	Type III secretion system lipoprotein chaperone (YscW)
J4N42_09500	COG1946	Acyl-CoA thioesterase
J4N42_09510	COG1522	sequence-specific DNA binding
J4N42_09515	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J4N42_09520	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J4N42_09530	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J4N42_09535	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J4N42_09540	COG2832	Protein of unknown function (DUF454)
J4N42_09545	COG0745	RESPONSE REGULATOR receiver
J4N42_09550	COG0583	DNA-binding transcription factor activity
J4N42_09555	COG0778	Nitroreductase
J4N42_09560	COG1250	3-hydroxyacyl-CoA dehydrogenase
J4N42_09560	COG1024	Enoyl-CoA hydratase
J4N42_09565	COG0183	Belongs to the thiolase family
J4N42_09590	COG2853	Lipoprotein
J4N42_09600	COG4235	cytochrome complex assembly
J4N42_09600	COG3088	subunit of a heme lyase
J4N42_09605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4N42_09610	COG1138	Cytochrome C-type biogenesis protein
J4N42_09625	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4N42_09630	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4N42_09635	COG4133	protoheme IX ABC transporter activity
J4N42_09645	COG0835	chemotaxis
J4N42_09655	COG1192	Involved in chromosome partitioning
J4N42_09660	COG2201	protein-glutamate methylesterase activity
J4N42_09665	COG0643	Histidine kinase
J4N42_09665	COG0784	Response regulator, receiver
J4N42_09665	COG2198	Histidine kinase
J4N42_09670	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
J4N42_09700	COG2062	phosphohistidine phosphatase, SixA
J4N42_09710	COG3102	Protein conserved in bacteria
J4N42_09740	COG4977	sequence-specific DNA binding
J4N42_09745	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
J4N42_09750	COG1121	(ABC) transporter
J4N42_09755	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J4N42_09760	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J4N42_09765	COG1286	toxin biosynthetic process
J4N42_09770	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
J4N42_09775	COG0285	dihydrofolate synthase activity
J4N42_09780	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J4N42_09785	COG0101	tRNA pseudouridine synthase activity
J4N42_09795	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J4N42_09800	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4N42_09805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J4N42_09810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4N42_09810	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
J4N42_09825	COG3101	peptidyl-lysine hydroxylation
J4N42_09830	COG2860	membrane
J4N42_09835	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J4N42_09840	COG2890	protein-(glutamine-N5) methyltransferase activity
J4N42_09855	COG1684	flagellar biosynthetic protein fliR
J4N42_09860	COG1987	bacterial-type flagellum assembly
J4N42_09910	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J4N42_09920	COG1677	Flagellar hook-basal body complex protein FliE
J4N42_09940	COG1516	flagellar protein fliS
J4N42_09950	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J4N42_09960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N42_09975	COG2837	iron assimilation
J4N42_09985	COG3088	subunit of a heme lyase
J4N42_09985	COG4235	cytochrome complex assembly
J4N42_09995	COG1138	Cytochrome C-type biogenesis protein
J4N42_10000	COG3301	Polysulphide reductase, NrfD
J4N42_10005	COG0437	4 iron, 4 sulfur cluster binding
J4N42_10015	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
J4N42_10020	COG0243	molybdopterin cofactor binding
J4N42_10025	COG1648	precorrin-2 dehydrogenase activity
J4N42_10025	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J4N42_10030	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4N42_10035	COG2146	nitrite reductase [NAD(P)H] activity
J4N42_10040	COG2223	nitrite transmembrane transporter activity
J4N42_10070	COG1393	Belongs to the ArsC family
J4N42_10090	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
J4N42_10100	COG2716	regulation of RNA biosynthetic process
J4N42_10105	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J4N42_10110	COG2194	sulfuric ester hydrolase activity
J4N42_10140	COG4783	chaperone-mediated protein folding
J4N42_10145	COG1393	Belongs to the ArsC family
J4N42_10165	COG2233	PERMEase
J4N42_10180	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J4N42_10185	COG2912	Transglutaminase-like superfamily
J4N42_10195	COG2890	protein-(glutamine-N5) methyltransferase activity
J4N42_10200	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J4N42_10205	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J4N42_10210	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
J4N42_10215	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J4N42_10220	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J4N42_10225	COG0193	aminoacyl-tRNA hydrolase activity
J4N42_10315	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N42_10320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N42_10330	COG1705	Flagellar rod assembly protein muramidase FlgJ
J4N42_10330	COG3951	Flagellar rod assembly protein muramidase FlgJ
J4N42_10335	COG1706	bacterial-type flagellum-dependent cell motility
J4N42_10350	COG4787	bacterial-type flagellum-dependent cell motility
J4N42_10355	COG1749	Flagellar hook protein flgE
J4N42_10370	COG1815	bacterial-type flagellum-dependent cell motility
J4N42_10375	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J4N42_10380	COG0835	chemotaxis
J4N42_10380	COG0784	Response regulator, receiver
J4N42_10440	COG2217	Heavy metal translocating P-type atpase
J4N42_10440	COG2608	mercury ion transmembrane transporter activity
J4N42_10480	COG2840	Smr protein MutS2
J4N42_10490	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J4N42_10495	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J4N42_10500	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J4N42_10505	COG0121	glutamine amidotransferase
J4N42_10510	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J4N42_10515	COG1960	acyl-CoA dehydrogenase activity
J4N42_10535	COG2226	methyltransferase
J4N42_10540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4N42_10545	COG1388	LysM domain
J4N42_10545	COG0741	lytic transglycosylase activity
J4N42_10555	COG3021	interspecies interaction between organisms
J4N42_10560	COG0347	Belongs to the P(II) protein family
J4N42_10575	COG0825	malonyl-CoA metabolic process
J4N42_10580	COG0587	DNA-directed DNA polymerase activity
J4N42_10595	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4N42_10600	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J4N42_10605	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4N42_10610	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
J4N42_10620	COG0750	zinc metalloprotease
J4N42_10625	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J4N42_10630	COG0575	Belongs to the CDS family
J4N42_10635	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J4N42_10640	COG0233	cytoplasmic translational termination
J4N42_10645	COG0528	UMP kinase activity
J4N42_10655	COG0052	Belongs to the universal ribosomal protein uS2 family
J4N42_10660	COG0024	Methionine aminopeptidase
J4N42_10675	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J4N42_10685	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J4N42_10705	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4N42_10705	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4N42_10710	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J4N42_10720	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J4N42_10725	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J4N42_10735	COG1073	alpha beta
J4N42_10740	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
J4N42_10745	COG2252	PERMEase
J4N42_10750	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4N42_10760	COG4067	protein conserved in archaea
J4N42_10760	COG0189	ligase activity
J4N42_10765	COG0189	ligase activity
J4N42_10775	COG0733	neurotransmitter:sodium symporter activity
J4N42_10790	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4N42_10795	COG0514	ATP-dependent DNA helicase (RecQ)
J4N42_10800	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J4N42_10815	COG1477	protein flavinylation
J4N42_10820	COG2871	sodium ion transport
J4N42_10825	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J4N42_10830	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J4N42_10845	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J4N42_10850	COG0271	Belongs to the BolA IbaG family
J4N42_10865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J4N42_10870	COG2211	Major facilitator Superfamily
J4N42_10880	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J4N42_10885	COG0693	protein deglycase activity
J4N42_10890	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J4N42_10895	COG2166	iron-sulfur cluster assembly
J4N42_10900	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J4N42_10905	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
J4N42_10925	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J4N42_10930	COG1074	ATP-dependent DNA helicase activity
J4N42_10935	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J4N42_10945	COG0583	DNA-binding transcription factor activity
J4N42_10950	COG3141	response to X-ray
J4N42_10955	COG3142	Participates in the control of copper homeostasis
J4N42_10995	COG0704	Plays a role in the regulation of phosphate uptake
J4N42_11000	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4N42_11005	COG0581	inorganic phosphate transmembrane transporter activity
J4N42_11015	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J4N42_11020	COG0248	Ppx GppA phosphatase
J4N42_11030	COG5002	protein histidine kinase activity
J4N42_11035	COG0745	RESPONSE REGULATOR receiver
J4N42_11045	COG0826	peptidase U32
J4N42_11050	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J4N42_11065	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N42_11070	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N42_11075	COG1862	Preprotein translocase
J4N42_11080	COG0343	queuine tRNA-ribosyltransferase activity
J4N42_11085	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J4N42_11090	COG0517	IMP dehydrogenase activity
J4N42_11100	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J4N42_11105	COG0583	DNA-binding transcription factor activity
J4N42_11110	COG0450	alkyl hydroperoxide reductase
J4N42_11115	COG2095	MarC family integral membrane protein
J4N42_11120	COG2171	N-acyltransferase activity
J4N42_11125	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J4N42_11135	COG1349	DNA-binding transcription factor activity
J4N42_11140	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J4N42_11155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4N42_11160	COG1609	Transcriptional regulator
J4N42_11165	COG2211	Major facilitator Superfamily
J4N42_11175	COG1609	Transcriptional regulator
J4N42_11180	COG2017	converts alpha-aldose to the beta-anomer
J4N42_11195	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4N42_11200	COG1609	Transcriptional regulator
J4N42_11205	COG3250	beta-galactosidase activity
J4N42_11210	COG2731	YhcH YjgK YiaL family protein
J4N42_11215	COG0531	amino acid
J4N42_11225	COG2207	Transcriptional regulator
J4N42_11235	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
J4N42_11235	COG3408	Glycogen debranching enzyme
J4N42_11245	COG3250	beta-galactosidase activity
J4N42_11255	COG0395	ABC-type sugar transport system, permease component
J4N42_11260	COG1175	transmembrane transport
J4N42_11270	COG0534	Mate efflux family protein
J4N42_11280	COG0583	DNA-binding transcription factor activity
J4N42_11320	COG4964	Belongs to the GSP D family
J4N42_11355	COG1022	Amp-dependent synthetase and ligase
J4N42_11365	COG0583	DNA-binding transcription factor activity
J4N42_11375	COG0583	DNA-binding transcription factor activity
J4N42_11380	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J4N42_11385	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J4N42_11395	COG0560	Phosphoserine phosphatase
J4N42_11405	COG0813	purine-nucleoside phosphorylase activity
J4N42_11410	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
J4N42_11415	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
J4N42_11420	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
J4N42_11425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4N42_11430	COG0084	hydrolase, TatD family'
J4N42_11440	COG3022	response to hydroperoxide
J4N42_11445	COG1115	amino acid carrier protein
J4N42_11460	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J4N42_11470	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
J4N42_11480	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J4N42_11485	COG0083	homoserine kinase activity
J4N42_11500	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J4N42_11510	COG0745	RESPONSE REGULATOR receiver
J4N42_11520	COG2198	Histidine kinase
J4N42_11520	COG5002	protein histidine kinase activity
J4N42_11520	COG0784	Response regulator, receiver
J4N42_11525	COG2203	Gaf domain
J4N42_11525	COG3706	GGDEF domain
J4N42_11525	COG4251	negative regulation of phosphorylation
J4N42_11525	COG5001	Diguanylate cyclase
J4N42_11530	COG1242	4 iron, 4 sulfur cluster binding
J4N42_11535	COG0067	glutamate synthase
J4N42_11535	COG0070	glutamate synthase
J4N42_11535	COG0069	glutamate synthase activity
J4N42_11545	COG0070	glutamate synthase
J4N42_11545	COG0069	glutamate synthase activity
J4N42_11545	COG0067	glutamate synthase
J4N42_11550	COG0493	'glutamate synthase
J4N42_11575	COG0195	Participates in both transcription termination and antitermination
J4N42_11580	COG0779	Required for maturation of 30S ribosomal subunits
J4N42_11595	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J4N42_11605	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J4N42_11610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J4N42_11615	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
J4N42_11620	COG1534	Rna-binding protein
J4N42_11625	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4N42_11635	COG2027	D-alanyl-D-alanine carboxypeptidase
J4N42_11645	COG2832	Protein of unknown function (DUF454)
J4N42_11650	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J4N42_11655	COG0739	heme binding
J4N42_11670	COG0316	Belongs to the HesB IscA family
J4N42_11675	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J4N42_11680	COG0628	permease
J4N42_11685	COG2813	Specifically methylates the guanine in position
J4N42_11705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N42_11710	COG0444	Belongs to the ABC transporter superfamily
J4N42_11715	COG4608	Belongs to the ABC transporter superfamily
J4N42_11725	COG2971	BadF BadG BcrA BcrD
J4N42_11740	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4N42_11745	COG3842	ATPase activity
J4N42_11755	COG1840	ABC-type Fe3 transport system, periplasmic component
J4N42_11760	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4N42_11765	COG0004	ammonium transporteR
J4N42_11780	COG1049	propionate catabolic process, 2-methylcitrate cycle
J4N42_11785	COG1752	Esterase of the alpha-beta hydrolase superfamily
J4N42_11790	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4N42_11795	COG1643	Atp-dependent helicase
J4N42_11805	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J4N42_11810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J4N42_11820	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J4N42_11825	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J4N42_11835	COG0842	Transport permease protein
J4N42_11840	COG1131	(ABC) transporter
J4N42_11845	COG0659	secondary active sulfate transmembrane transporter activity
J4N42_11850	COG0288	reversible hydration of carbon dioxide
J4N42_11865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N42_11870	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4N42_11875	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
J4N42_11880	COG2186	Transcriptional regulator
J4N42_11885	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J4N42_11890	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4N42_11895	COG4974	Belongs to the 'phage' integrase family
J4N42_11900	COG0716	FMN binding
J4N42_11910	COG0157	Belongs to the NadC ModD family
J4N42_11920	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4N42_11925	COG1459	type II secretion system
J4N42_11935	COG0237	dephospho-CoA kinase activity
J4N42_11940	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
J4N42_11950	COG0148	phosphopyruvate hydratase activity
J4N42_11960	COG3956	TIGRFAM MazG family protein
J4N42_11965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J4N42_11970	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J4N42_11975	COG4999	Histidine kinase
J4N42_11975	COG3850	Histidine kinase
J4N42_11975	COG3437	response regulator, receiver
J4N42_11975	COG2205	protein histidine kinase activity
J4N42_12000	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J4N42_12005	COG1381	Involved in DNA repair and RecF pathway recombination
J4N42_12010	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J4N42_12015	COG0571	ribonuclease III activity
J4N42_12030	COG3086	response to oxidative stress
J4N42_12040	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
J4N42_12045	COG1595	DNA-templated transcription, initiation
J4N42_12050	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J4N42_12060	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J4N42_12065	COG0354	folic acid binding
J4N42_12080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N42_12085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N42_12090	COG3079	Belongs to the UPF0149 family
J4N42_12095	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
J4N42_12105	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J4N42_12115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4N42_12125	COG0028	Belongs to the TPP enzyme family
J4N42_12130	COG1022	Amp-dependent synthetase and ligase
J4N42_12135	COG0583	DNA-binding transcription factor activity
J4N42_12160	COG1309	transcriptional regulator
J4N42_12165	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J4N42_12170	COG0473	3-isopropylmalate dehydrogenase activity
J4N42_12250	COG0795	lipopolysaccharide-transporting ATPase activity
J4N42_12255	COG0795	lipopolysaccharide-transporting ATPase activity
J4N42_12265	COG2927	DNA polymerase III (CHI subunit)
J4N42_12270	COG0525	valine-tRNA ligase activity
J4N42_12280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J4N42_12285	COG0564	pseudouridine synthase activity
J4N42_12300	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J4N42_12315	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
J4N42_12320	COG0251	oxidation-reduction process
J4N42_12325	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
J4N42_12330	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
J4N42_12340	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J4N42_12345	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J4N42_12350	COG2967	ApaG domain
J4N42_12365	COG3610	response to peptide
J4N42_12370	COG2966	Psort location CytoplasmicMembrane, score
J4N42_12375	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J4N42_12385	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J4N42_12390	COG0142	geranyltranstransferase activity
J4N42_12395	COG0039	L-malate dehydrogenase activity
J4N42_12400	COG1438	arginine binding
J4N42_12405	COG2358	TRAP transporter, solute receptor (TAXI family
J4N42_12415	COG0589	response to stress
J4N42_12430	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J4N42_12450	COG2356	endonuclease I
J4N42_12455	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J4N42_12460	COG0189	ligase activity
J4N42_12465	COG1678	Uncharacterized ACR, COG1678
J4N42_12470	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J4N42_12485	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J4N42_12490	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J4N42_12495	COG0762	integral membrane protein
J4N42_12510	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J4N42_12515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J4N42_12520	COG0646	methionine synthase
J4N42_12520	COG1410	methionine synthase
J4N42_12585	COG0175	sulfate reduction
J4N42_12595	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J4N42_12620	COG0735	belongs to the Fur family
J4N42_12635	COG0432	Pfam Uncharacterised protein family UPF0047
J4N42_12645	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J4N42_12670	COG2965	DNA replication, synthesis of RNA primer
J4N42_12685	COG2906	2 iron, 2 sulfur cluster binding
J4N42_12690	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J4N42_12695	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J4N42_12710	COG2168	tRNA wobble position uridine thiolation
J4N42_12715	COG2923	Belongs to the DsrF TusC family
J4N42_12720	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
J4N42_12725	COG2964	Protein conserved in bacteria
J4N42_12730	COG0545	Peptidyl-prolyl cis-trans isomerase
J4N42_12740	COG2900	Belongs to the SlyX family
J4N42_12745	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
J4N42_12750	COG0330	HflC and HflK could
J4N42_12755	COG0330	HflC and HflK could
J4N42_12760	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J4N42_12770	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J4N42_12775	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J4N42_12785	COG0802	atpase or kinase
J4N42_12790	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J4N42_12850	COG1162	GTPase activity
J4N42_12860	COG0471	metal ion transport
J4N42_12860	COG0490	domain, Protein
J4N42_12875	COG4942	peptidase
J4N42_12900	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
J4N42_12910	COG0085	RNA polymerase activity
J4N42_12920	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J4N42_12935	COG0250	Participates in transcription elongation, termination and antitermination
J4N42_12940	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J4N42_12945	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J4N42_12970	COG1072	(Pantothenic acid kinase))
J4N42_12985	COG0149	triose-phosphate isomerase activity
J4N42_12995	COG0534	Mate efflux family protein
J4N42_13000	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J4N42_13005	COG1575	Belongs to the MenA family. Type 1 subfamily
J4N42_13015	COG1509	lysine 2,3-aminomutase activity
J4N42_13020	COG1285	pathogenesis
J4N42_13025	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J4N42_13030	COG0205	6-phosphofructokinase activity
J4N42_13045	COG0745	RESPONSE REGULATOR receiver
J4N42_13050	COG2205	protein histidine kinase activity
J4N42_13055	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J4N42_13060	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J4N42_13070	COG1027	Aspartate ammonia-lyase
J4N42_13075	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J4N42_13080	COG1288	antiporter activity
J4N42_13090	COG0549	Belongs to the carbamate kinase family
J4N42_13095	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J4N42_13100	COG0540	Belongs to the ATCase OTCase family
J4N42_13105	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
J4N42_13110	COG1438	arginine binding
J4N42_13115	COG4232	protein-disulfide reductase activity
J4N42_13125	COG3263	regulation of cellular component size
J4N42_13135	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N42_13155	COG0679	Auxin Efflux Carrier
J4N42_13165	COG1461	Dihydroxyacetone kinase
J4N42_13170	COG2376	Dihydroxyacetone kinase
J4N42_13180	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J4N42_13180	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N42_13190	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J4N42_13195	COG0698	ribose 5-phosphate isomerase
J4N42_13200	COG1494	fructose-1,6-bisphosphatase
J4N42_13210	COG2205	protein histidine kinase activity
J4N42_13210	COG0784	Response regulator, receiver
J4N42_13210	COG2198	Histidine kinase
J4N42_13215	COG2814	Major facilitator Superfamily
J4N42_13230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J4N42_13235	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J4N42_13240	COG0511	ligase activity, forming carbon-carbon bonds
J4N42_13245	COG0439	Biotin carboxylase
J4N42_13250	COG2264	protein methyltransferase activity
J4N42_13255	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4N42_13260	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
J4N42_13265	COG0840	transmembrane signaling receptor activity
J4N42_13270	COG0789	Transcriptional regulator
J4N42_13275	COG0138	bifunctional purine biosynthesis protein purh
J4N42_13280	COG0151	Belongs to the GarS family
J4N42_13295	COG1253	flavin adenine dinucleotide binding
J4N42_13310	COG1573	uracil-dna glycosylase
J4N42_13390	COG0724	RNA recognition motif
J4N42_13395	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J4N42_13405	COG4206	TonB-dependent receptor
J4N42_13425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N42_13430	COG0534	Mate efflux family protein
J4N42_13435	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
J4N42_13440	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J4N42_13445	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J4N42_13450	COG2937	Belongs to the GPAT DAPAT family
J4N42_13460	COG3161	chorismate lyase activity
J4N42_13465	COG1580	Controls the rotational direction of flagella during chemotaxis
J4N42_13470	COG0705	Rhomboid family
J4N42_13485	COG2177	Part of the ABC transporter FtsEX involved in
J4N42_13490	COG2884	Cell division ATP-binding protein ftsE
J4N42_13495	COG0552	protein localization to endoplasmic reticulum
J4N42_13500	COG0742	ribosomal rna small subunit methyltransferase
J4N42_13510	COG2095	MarC family integral membrane protein
J4N42_13525	COG1335	isochorismatase
J4N42_13535	COG0583	DNA-binding transcription factor activity
J4N42_13565	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J4N42_13570	COG0640	Transcriptional regulator
J4N42_13575	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J4N42_13580	COG1280	lysine exporter protein (LysE YggA)
J4N42_13585	COG2267	carboxylic ester hydrolase activity
J4N42_13590	COG0561	phosphatase activity
J4N42_13605	COG3148	PFAM DTW domain containing protein
J4N42_13610	COG1011	Hydrolase
J4N42_13615	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J4N42_13625	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J4N42_13630	COG0019	diaminopimelate decarboxylase activity
J4N42_13640	COG1965	Belongs to the frataxin family
J4N42_13655	COG1587	Uroporphyrinogen-III synthase
J4N42_13660	COG2959	enzyme of heme biosynthesis
J4N42_13665	COG3071	HemY protein
J4N42_13715	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
J4N42_13730	COG3118	belongs to the thioredoxin family
J4N42_13740	COG0248	Ppx GppA phosphatase
J4N42_13750	COG1253	flavin adenine dinucleotide binding
J4N42_13760	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J4N42_13770	COG0514	ATP-dependent DNA helicase (RecQ)
J4N42_13775	COG2962	Rard protein
J4N42_13785	COG1280	lysine exporter protein (LysE YggA)
J4N42_13790	COG0405	Gamma-glutamyltransferase
J4N42_13800	COG0210	DNA helicase
J4N42_13810	COG3220	belongs to the UPF0276 family
J4N42_13830	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J4N42_13840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N42_13845	COG0800	Aldolase
J4N42_13850	COG2610	gluconate transmembrane transporter activity
J4N42_13855	COG3265	gluconokinase activity
J4N42_13860	COG0129	dihydroxy-acid dehydratase activity
J4N42_13865	COG1609	Transcriptional regulator
J4N42_13885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N42_13890	COG0601	transmembrane transport
J4N42_13940	COG1309	transcriptional regulator
J4N42_13945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N42_13950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N42_13955	COG2960	long-chain fatty acid transporting porin activity
J4N42_13960	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J4N42_13965	COG0583	DNA-binding transcription factor activity
J4N42_13980	COG3078	GTPase activator activity
J4N42_14000	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4N42_14000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4N42_14015	COG0084	hydrolase, TatD family'
J4N42_14020	COG0805	protein transport
J4N42_14025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J4N42_14040	COG3165	ubiquinone biosynthetic process from chorismate
J4N42_14045	COG2226	methyltransferase
J4N42_14050	COG1322	Protein conserved in bacteria
J4N42_14075	COG2081	HI0933 family
J4N42_14085	COG1528	Iron-storage protein
J4N42_14090	COG0589	response to stress
J4N42_14105	COG0742	ribosomal rna small subunit methyltransferase
J4N42_14110	COG5001	Diguanylate cyclase
J4N42_14110	COG5002	protein histidine kinase activity
J4N42_14115	COG1522	sequence-specific DNA binding
J4N42_14135	COG0006	proline dipeptidase activity
J4N42_14135	COG0006	proline dipeptidase activity
J4N42_14145	COG2022	thiamine diphosphate biosynthetic process
J4N42_14155	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J4N42_14160	COG0352	thiamine-phosphate diphosphorylase activity
J4N42_14165	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
J4N42_14170	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J4N42_14225	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4N42_14230	COG1739	Uncharacterized protein family UPF0029
J4N42_14235	COG1250	3-hydroxyacyl-CoA dehydrogenase
J4N42_14235	COG1024	Enoyl-CoA hydratase
J4N42_14240	COG0183	Belongs to the thiolase family
J4N42_14245	COG0583	DNA-binding transcription factor activity
J4N42_14250	COG2814	Major facilitator Superfamily
J4N42_14260	COG0765	amino acid transport
J4N42_14270	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J4N42_14275	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J4N42_14280	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J4N42_14290	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J4N42_14295	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J4N42_14310	COG3312	ion transport
J4N42_14315	COG1475	DNA binding
J4N42_14320	COG1192	Involved in chromosome partitioning
J4N42_14325	COG0357	Ribosomal RNA small subunit methyltransferase G
J4N42_14330	COG0445	tRNA wobble uridine modification
J4N42_14335	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J4N42_14345	COG0706	membrane insertase activity
J4N42_14350	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J4N42_14355	COG0594	ribonuclease P activity
J4N42_14360	COG0230	Belongs to the bacterial ribosomal protein bL34 family
J4N42_14365	COG1126	abc transporter atp-binding protein
J4N42_14390	COG1444	tRNA N-acetyltransferase activity
J4N42_14400	COG0745	RESPONSE REGULATOR receiver
J4N42_14410	COG0835	chemotaxis
J4N42_14415	COG0835	chemotaxis
J4N42_14420	COG0840	transmembrane signaling receptor activity
J4N42_14425	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J4N42_14470	COG1234	tRNA 3'-trailer cleavage
J4N42_14525	COG2205	protein histidine kinase activity
J4N42_14565	COG2723	6-phospho-beta-galactosidase activity
J4N42_14575	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
J4N42_14580	COG1263	PTS System
J4N42_14580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N42_14585	COG1472	Belongs to the glycosyl hydrolase 3 family
J4N42_14615	COG1280	lysine exporter protein (LysE YggA)
J4N42_14625	COG0702	epimerase
J4N42_14630	COG1132	(ABC) transporter
J4N42_14670	COG0641	radical SAM
J4N42_14675	COG3119	arylsulfatase activity
J4N42_14680	COG1309	transcriptional regulator
J4N42_14730	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J4N42_14750	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J4N42_14765	COG4221	oxidoreductase activity
J4N42_14775	COG0415	Belongs to the DNA photolyase family
J4N42_14790	COG1595	DNA-templated transcription, initiation
J4N42_14800	COG3501	Rhs element vgr protein
J4N42_14820	COG3788	relative of glutathione S-transferase, MAPEG superfamily
J4N42_14850	COG0596	Alpha beta hydrolase
J4N42_14855	COG0471	metal ion transport
J4N42_14860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N42_14865	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J4N42_14870	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
J4N42_14875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N42_14890	COG2188	Transcriptional regulator
J4N42_14895	COG1131	(ABC) transporter
J4N42_14925	COG0259	pyridoxamine-phosphate oxidase activity
J4N42_14935	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J4N42_14960	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N42_14975	COG0739	heme binding
J4N42_14990	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
J4N42_14995	COG1162	GTPase activity
J4N42_15005	COG1999	signal sequence binding
J4N42_15020	COG0786	glutamate:sodium symporter activity
J4N42_15055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4N42_15070	COG2814	Major facilitator Superfamily
J4N42_15075	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N42_15090	COG2329	Antibiotic biosynthesis monooxygenase
J4N42_15110	COG0583	DNA-binding transcription factor activity
J4N42_15120	COG4580	involved in the transport of maltose and maltodextrins
J4N42_15140	COG0363	glucosamine-6-phosphate deaminase activity
J4N42_15165	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
J4N42_15180	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
J4N42_15185	COG3366	ferrous iron transmembrane transporter activity
J4N42_15190	COG0700	Nucleoside recognition
J4N42_15195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J4N42_15200	COG5002	protein histidine kinase activity
J4N42_15200	COG5001	Diguanylate cyclase
J4N42_15210	COG2200	EAL domain
J4N42_15215	COG0840	transmembrane signaling receptor activity
J4N42_15225	COG1301	dicarboxylic acid transport
J4N42_15230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4N42_15260	COG0778	Nitroreductase
J4N42_15280	COG0454	-acetyltransferase
J4N42_15295	COG4667	esterase of the alpha-beta hydrolase superfamily
J4N42_15305	COG1215	transferase activity, transferring glycosyl groups
J4N42_15310	COG0438	transferase activity, transferring glycosyl groups
J4N42_15335	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J4N42_15345	COG0523	cobalamin synthesis protein
J4N42_15350	COG2988	succinylglutamate desuccinylase activity
J4N42_15355	COG0739	heme binding
J4N42_15360	COG2866	Carboxypeptidase
J4N42_15370	COG0671	phosphoesterase, PA-phosphatase related
J4N42_15375	COG0583	DNA-binding transcription factor activity
J4N42_15380	COG0534	Mate efflux family protein
J4N42_15390	COG4413	Urea transporter
J4N42_15395	COG0840	transmembrane signaling receptor activity
J4N42_15405	COG0488	(ABC) transporter
J4N42_15430	COG2199	diguanylate cyclase activity
J4N42_15430	COG2200	EAL domain
J4N42_15430	COG2202	Pas domain
J4N42_15490	COG0783	Belongs to the Dps family
J4N42_15495	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J4N42_15510	COG4948	Mandelate Racemase Muconate Lactonizing
J4N42_15520	COG0583	DNA-binding transcription factor activity
J4N42_15580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N42_15590	COG4175	Glycine betaine
J4N42_15595	COG4176	ABC-type proline glycine betaine transport system permease component
J4N42_15610	COG1012	belongs to the aldehyde dehydrogenase family
J4N42_15615	COG1309	transcriptional regulator
J4N42_15620	COG3383	formate dehydrogenase (NAD+) activity
J4N42_15625	COG5492	domain, Protein
J4N42_15630	COG2197	response regulator
J4N42_15635	COG1902	pentaerythritol trinitrate reductase activity
J4N42_15670	COG0583	DNA-binding transcription factor activity
J4N42_15675	COG0596	Alpha beta hydrolase
J4N42_15685	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4N42_15695	COG0318	PFAM AMP-dependent synthetase and ligase
J4N42_15705	COG0386	Belongs to the glutathione peroxidase family
J4N42_15710	COG1846	Transcriptional regulator
J4N42_15745	COG0753	catalase activity
J4N42_15760	COG2130	NADP-dependent
J4N42_15765	COG1309	transcriptional regulator
J4N42_15775	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4N42_15785	COG1278	Cold shock
J4N42_15795	COG1733	regulation of RNA biosynthetic process
J4N42_15800	COG1028	Short-chain dehydrogenase reductase Sdr
J4N42_15810	COG0110	maltose O-acetyltransferase activity
J4N42_15835	COG0573	inorganic phosphate transmembrane transporter activity
J4N42_15850	COG3300	MHYT domain
J4N42_15850	COG5001	Diguanylate cyclase
J4N42_15860	COG0840	transmembrane signaling receptor activity
J4N42_15870	COG5001	Diguanylate cyclase
J4N42_15870	COG3300	MHYT domain
J4N42_15875	COG2204	response regulator
J4N42_15880	COG1609	Transcriptional regulator
J4N42_15895	COG0395	ABC-type sugar transport system, permease component
J4N42_15900	COG2723	6-phospho-beta-galactosidase activity
J4N42_15905	COG3842	ATPase activity
J4N42_15910	COG3459	Glycosyltransferase 36 associated
J4N42_15915	COG2017	converts alpha-aldose to the beta-anomer
J4N42_15925	COG1609	Transcriptional regulator
J4N42_15945	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J4N42_15950	COG1012	belongs to the aldehyde dehydrogenase family
J4N42_15955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J4N42_15960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N42_15980	COG3314	Sporulation integral membrane protein YlbJ
J4N42_16005	COG0739	heme binding
J4N42_16010	COG5001	Diguanylate cyclase
J4N42_16020	COG2814	Major facilitator Superfamily
J4N42_16035	COG0697	spore germination
J4N42_16040	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J4N42_16050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4N42_16055	COG4232	protein-disulfide reductase activity
J4N42_16065	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J4N42_16075	COG0179	Fumarylacetoacetate (FAA) hydrolase
J4N42_16095	COG1280	lysine exporter protein (LysE YggA)
J4N42_16100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4N42_16110	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J4N42_16115	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
J4N42_16140	COG1612	heme a metabolic process
J4N42_16145	COG0109	protoheme IX farnesyltransferase activity
J4N42_16155	COG0765	amino acid transport
J4N42_16160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N42_16170	COG1126	abc transporter atp-binding protein
J4N42_16175	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4N42_16205	COG2267	carboxylic ester hydrolase activity
J4N42_16210	COG2067	long-chain fatty acid transport protein
J4N42_16225	COG0366	Alpha amylase catalytic
J4N42_16240	COG4989	oxidoreductase activity
J4N42_16250	COG1136	(ABC) transporter
J4N42_16255	COG4591	ABC-type transport system involved in lipoprotein release permease component
J4N42_16270	COG3275	phosphorelay sensor kinase activity
J4N42_16275	COG3279	Response regulator of the LytR AlgR family
J4N42_16280	COG4251	negative regulation of phosphorylation
J4N42_16280	COG2203	Gaf domain
J4N42_16280	COG3706	GGDEF domain
J4N42_16280	COG5001	Diguanylate cyclase
J4N42_16305	COG0583	DNA-binding transcription factor activity
J4N42_16315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N42_16350	COG0534	Mate efflux family protein
J4N42_16360	COG3604	Transcriptional regulator
J4N42_16365	COG1017	nitric oxide dioxygenase activity
J4N42_16365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4N42_16380	COG1278	Cold shock
J4N42_16385	COG3036	rescue of stalled ribosome
J4N42_16400	COG1686	Belongs to the peptidase S11 family
J4N42_16415	COG3530	Putative quorum-sensing-regulated virulence factor
J4N42_16450	COG1027	Aspartate ammonia-lyase
J4N42_16455	COG1012	belongs to the aldehyde dehydrogenase family
J4N42_16460	COG0583	DNA-binding transcription factor activity
J4N42_16465	COG0667	Aldo Keto reductase
J4N42_16470	COG0006	proline dipeptidase activity
J4N42_16475	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N42_16480	COG4974	Belongs to the 'phage' integrase family
J4N42_16490	COG1733	regulation of RNA biosynthetic process
J4N42_16500	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J4N42_16520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J4N42_16540	COG0726	polysaccharide deacetylase
J4N42_16545	COG0583	DNA-binding transcription factor activity
J4N42_16555	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J4N42_16570	COG2731	YhcH YjgK YiaL family protein
J4N42_16575	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N42_16585	COG1737	Transcriptional regulator
J4N42_16590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J4N42_16595	COG1869	D-ribose catabolic process
J4N42_16600	COG1129	ABC transporter
J4N42_16605	COG1172	Belongs to the binding-protein-dependent transport system permease family
J4N42_16610	COG1879	ABC-type sugar transport system periplasmic component
J4N42_16615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N42_16630	COG5002	protein histidine kinase activity
J4N42_16635	COG0745	RESPONSE REGULATOR receiver
J4N42_16655	COG0840	transmembrane signaling receptor activity
J4N42_16670	COG2015	COG2015, Alkyl sulfatase and related hydrolases
J4N42_16690	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J4N42_16700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N42_16715	COG1609	Transcriptional regulator
J4N42_16725	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J4N42_16730	COG1028	Short-chain dehydrogenase reductase Sdr
J4N42_16745	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J4N42_16750	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J4N42_16755	COG1845	cytochrome c oxidase, subunit III
J4N42_16760	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J4N42_16790	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J4N42_16800	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
J4N42_16805	COG0513	Belongs to the DEAD box helicase family
J4N42_16815	COG1012	belongs to the aldehyde dehydrogenase family
J4N42_16820	COG3284	Transcriptional regulator
J4N42_16850	COG2207	Transcriptional regulator
J4N42_16860	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J4N42_16865	COG0363	glucosamine-6-phosphate deaminase activity
J4N42_16870	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J4N42_16875	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J4N42_16905	COG0346	lactoylglutathione lyase activity
J4N42_16930	COG0156	8-amino-7-oxononanoate synthase activity
J4N42_17000	COG5001	Diguanylate cyclase
J4N42_17005	COG0798	PFAM Bile acid sodium symporter
J4N42_17085	COG0668	transmembrane transport
J4N42_17090	COG0583	DNA-binding transcription factor activity
J4N42_17100	COG2239	Acts as a magnesium transporter
J4N42_17110	COG0387	Pfam Sodium calcium exchanger
J4N42_17115	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N42_17120	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N42_17140	COG1304	FMN binding
J4N42_17145	COG1620	l-lactate permease
J4N42_17150	COG0583	DNA-binding transcription factor activity
J4N42_17155	COG4172	Belongs to the ABC transporter superfamily
J4N42_17165	COG1067	ATP-dependent peptidase activity
J4N42_17205	COG0831	urea catabolic process
J4N42_17210	COG0832	Belongs to the urease beta subunit family
J4N42_17215	COG0804	urea catabolic process
J4N42_17220	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
J4N42_17235	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
J4N42_17245	COG3706	GGDEF domain
J4N42_17250	COG4251	negative regulation of phosphorylation
J4N42_17250	COG3706	GGDEF domain
J4N42_17250	COG2203	Gaf domain
J4N42_17250	COG5001	Diguanylate cyclase
J4N42_17260	COG2304	oxidoreductase activity
J4N42_17280	COG0714	Associated with various cellular activities
J4N42_17290	COG0418	dihydroorotase activity
J4N42_17295	COG0401	homolog of Blt101
J4N42_17300	COG3217	Mosc domain protein beta barrel domain protein
J4N42_17300	COG0633	Ferredoxin
J4N42_17300	COG3217	Mosc domain protein beta barrel domain protein
J4N42_17300	COG0633	Ferredoxin
J4N42_17335	COG0366	Alpha amylase catalytic
J4N42_17365	COG0745	RESPONSE REGULATOR receiver
J4N42_17375	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J4N42_17375	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J4N42_17385	COG0516	GMP reductase activity
J4N42_17395	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J4N42_17425	COG1566	PFAM secretion protein HlyD family protein
J4N42_17435	COG0628	permease
J4N42_17455	COG0668	transmembrane transport
J4N42_17465	COG2926	Belongs to the UPF0265 family
J4N42_17475	COG3132	Protein of unknown function, DUF480
J4N42_17480	COG2827	Endonuclease containing a URI domain
J4N42_17520	COG1289	transmembrane transporter activity
J4N42_17525	COG0210	DNA helicase
J4N42_17530	COG1803	Methylglyoxal synthase
J4N42_17535	COG1879	ABC-type sugar transport system periplasmic component
J4N42_17540	COG0784	Response regulator, receiver
J4N42_17540	COG2198	Histidine kinase
J4N42_17540	COG2205	protein histidine kinase activity
J4N42_17545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N42_17560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N42_17580	COG0484	heat shock protein binding
J4N42_17590	COG1716	ATPase activity
J4N42_17590	COG5001	Diguanylate cyclase
J4N42_17595	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J4N42_17605	COG4181	ATPase activity
J4N42_17610	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
J4N42_17620	COG1984	allophanate hydrolase subunit 2
J4N42_17630	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
J4N42_17645	COG3447	MASE1 domain protein
J4N42_17645	COG5001	Diguanylate cyclase
J4N42_17645	COG5002	protein histidine kinase activity
J4N42_17650	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4N42_17680	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J4N42_17680	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
J4N42_17685	COG3850	Histidine kinase
J4N42_17690	COG2197	response regulator
J4N42_17695	COG3069	C4-dicarboxylate transmembrane transporter activity
J4N42_17700	COG4943	cyclic-guanylate-specific phosphodiesterase activity
J4N42_17720	COG3038	cytochrome b561
J4N42_17730	COG0583	DNA-binding transcription factor activity
J4N42_17750	COG3593	DNA synthesis involved in DNA repair
J4N42_17755	COG0737	Belongs to the 5'-nucleotidase family
J4N42_17760	COG0420	3'-5' exonuclease activity
J4N42_17765	COG0419	ATPase involved in DNA repair
J4N42_17770	COG0784	Response regulator, receiver
J4N42_17770	COG2205	protein histidine kinase activity
J4N42_17775	COG2067	long-chain fatty acid transport protein
J4N42_17795	COG0156	8-amino-7-oxononanoate synthase activity
J4N42_17805	COG0038	chloride channel
J4N42_17810	COG0523	cobalamin synthesis protein
J4N42_17815	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J4N42_17825	COG0574	Belongs to the PEP-utilizing enzyme family
J4N42_17825	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J4N42_17830	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
J4N42_17835	COG0840	transmembrane signaling receptor activity
J4N42_17845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N42_17850	COG0545	Peptidyl-prolyl cis-trans isomerase
J4N42_17875	COG1522	sequence-specific DNA binding
J4N42_17900	COG2897	thiosulfate sulfurtransferase activity
J4N42_17935	COG0513	Belongs to the DEAD box helicase family
J4N42_17945	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J4N42_17950	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N42_17950	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N42_17955	COG2759	Belongs to the formate--tetrahydrofolate ligase family
J4N42_17965	COG1979	alcohol dehydrogenase
J4N42_17970	COG2207	Transcriptional regulator
J4N42_17980	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J4N42_17985	COG3447	MASE1 domain protein
J4N42_17985	COG5002	protein histidine kinase activity
J4N42_17985	COG5001	Diguanylate cyclase
J4N42_17990	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N42_17990	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N42_17990	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
J4N42_17995	COG1105	Belongs to the carbohydrate kinase PfkB family
J4N42_18000	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N42_18000	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N42_18005	COG1609	Transcriptional regulator
J4N42_18030	COG0745	RESPONSE REGULATOR receiver
J4N42_18040	COG3706	GGDEF domain
J4N42_18055	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J4N42_18060	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
J4N42_18070	COG0745	RESPONSE REGULATOR receiver
J4N42_18085	COG3140	Belongs to the UPF0181 family
J4N42_18140	COG4128	Pfam Zonular occludens toxin
J4N42_18185	COG4128	Pfam Zonular occludens toxin
J4N42_18230	COG4128	Pfam Zonular occludens toxin
J4N42_18235	COG0023	Translation Initiation Factor
J4N42_18260	COG1042	CoA-binding domain protein
J4N42_18260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N42_18260	COG0045	succinate-CoA ligase (ADP-forming) activity
J4N42_18265	COG0583	DNA-binding transcription factor activity
J4N42_18280	COG4533	DNA binding
J4N42_18290	COG2050	protein possibly involved in aromatic compounds catabolism
J4N42_18295	COG0501	Belongs to the peptidase M48B family
J4N42_18300	COG0750	zinc metalloprotease
J4N42_18325	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J4N42_18330	COG3118	belongs to the thioredoxin family
J4N42_18335	COG0477	Major facilitator Superfamily
J4N42_18390	COG2425	protein containing a von Willebrand factor type A (vWA) domain
J4N42_18405	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
J4N42_18420	COG1794	racemase activity, acting on amino acids and derivatives
J4N42_18485	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4N42_18510	COG0625	glutathione transferase activity
J4N42_18545	COG1742	UPF0060 membrane protein
J4N42_18580	COG0561	phosphatase activity
J4N42_18585	COG1028	Short-chain dehydrogenase reductase Sdr
J4N42_18595	COG1024	Enoyl-CoA hydratase
J4N42_18600	COG1024	Enoyl-CoA hydratase
J4N42_18605	COG1960	acyl-CoA dehydrogenase activity
J4N42_18615	COG0183	Belongs to the thiolase family
J4N42_18625	COG1960	acyl-CoA dehydrogenase activity
J4N42_18630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J4N42_18635	COG1024	Enoyl-CoA hydratase
J4N42_18660	COG2197	response regulator
J4N42_18685	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J4N42_18690	COG2159	amidohydrolase
J4N42_18695	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J4N42_18700	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J4N42_18705	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J4N42_18710	COG0673	inositol 2-dehydrogenase activity
J4N42_18720	COG0673	inositol 2-dehydrogenase activity
J4N42_18735	COG0679	Auxin Efflux Carrier
J4N42_18740	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N42_18750	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J4N42_18755	COG0583	DNA-binding transcription factor activity
J4N42_18770	COG0667	Aldo Keto reductase
J4N42_18790	COG1733	regulation of RNA biosynthetic process
J4N42_18815	COG3706	GGDEF domain
J4N42_18820	COG0840	transmembrane signaling receptor activity
J4N42_18825	COG0840	transmembrane signaling receptor activity
J4N42_18840	COG2271	Major facilitator Superfamily
J4N42_18855	COG0641	radical SAM
J4N42_18865	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
J4N42_18870	COG0655	NAD(P)H dehydrogenase (quinone) activity
J4N42_18895	COG0110	maltose O-acetyltransferase activity
J4N42_18900	COG0583	DNA-binding transcription factor activity
J4N42_18930	COG0714	Associated with various cellular activities
J4N42_18940	COG3119	arylsulfatase activity
J4N42_18950	COG2203	Gaf domain
J4N42_18950	COG5001	Diguanylate cyclase
J4N42_18950	COG4251	negative regulation of phosphorylation
J4N42_18950	COG3706	GGDEF domain
J4N42_18955	COG1473	amidohydrolase
J4N42_18960	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J4N42_18975	COG4067	protein conserved in archaea
J4N42_18975	COG0189	ligase activity
J4N42_18985	COG4115	mRNA cleavage
J4N42_18990	COG2161	toxin-antitoxin pair type II binding
J4N42_19025	COG0602	queuosine metabolic process
J4N42_19030	COG1328	CTP reductase activity
J4N42_19050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4N42_19055	COG0813	purine-nucleoside phosphorylase activity
J4N42_19060	COG0402	S-adenosylhomocysteine deaminase activity
J4N42_19080	COG0446	pyridine nucleotide-disulphide oxidoreductase
J4N42_19100	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
J4N42_19110	COG0534	Mate efflux family protein
J4N42_19130	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
J4N42_19135	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J4N42_19140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J4N42_19145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J4N42_19150	COG1116	anion transmembrane transporter activity
J4N42_19155	COG0351	phosphomethylpyrimidine kinase
J4N42_19160	COG0583	DNA-binding transcription factor activity
J4N42_19170	COG2814	Major facilitator Superfamily
J4N42_19185	COG0183	Belongs to the thiolase family
J4N42_19200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N42_19205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N42_19210	COG1309	transcriptional regulator
J4N42_19215	COG0513	Belongs to the DEAD box helicase family
J4N42_19220	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
J4N42_19225	COG0814	amino acid
J4N42_19230	COG0840	transmembrane signaling receptor activity
J4N42_19235	COG3706	GGDEF domain
J4N42_19240	COG2169	Transcriptional regulator
J4N42_19245	COG1486	melibiose metabolic process
J4N42_19250	COG2211	Major facilitator Superfamily
J4N42_19275	COG0443	Heat shock 70 kDa protein
J4N42_19290	COG2814	Major facilitator Superfamily
J4N42_19300	COG2199	diguanylate cyclase activity
J4N42_19300	COG2203	Gaf domain
J4N42_19310	COG4191	Histidine kinase
J4N42_19310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N42_19315	COG0784	Response regulator, receiver
J4N42_19315	COG3437	response regulator, receiver
J4N42_19320	COG0004	ammonium transporteR
J4N42_19325	COG0840	transmembrane signaling receptor activity
J4N42_19340	COG0534	Mate efflux family protein
J4N42_19355	COG0840	transmembrane signaling receptor activity
J4N42_19395	COG0653	protein targeting
J4N42_19410	COG0346	lactoylglutathione lyase activity
J4N42_19420	COG4628	conserved protein (DUF2132)
J4N42_19440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N42_19445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4N42_19445	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4N42_19455	COG0730	response to heat
J4N42_19470	COG1418	mRNA catabolic process
J4N42_19490	COG0673	inositol 2-dehydrogenase activity
J4N42_19500	COG0583	DNA-binding transcription factor activity
J4N42_19505	COG4628	conserved protein (DUF2132)
J4N42_19510	COG0513	Belongs to the DEAD box helicase family
J4N42_19540	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J4N42_19545	COG5001	Diguanylate cyclase
J4N42_19545	COG3300	MHYT domain
J4N42_19550	COG0789	Transcriptional regulator
J4N42_19560	COG0583	DNA-binding transcription factor activity
J4N42_19575	COG5001	Diguanylate cyclase
J4N42_19575	COG1716	ATPase activity
J4N42_19585	COG4172	Belongs to the ABC transporter superfamily
J4N42_19590	COG4239	(ABC) transporter, permease
J4N42_19595	COG4174	ABC transporter (Permease)
J4N42_19600	COG4166	transmembrane transport
J4N42_19635	COG4264	IucA IucC family
J4N42_19650	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J4N42_19660	COG0402	S-adenosylhomocysteine deaminase activity
J4N42_19675	COG0583	DNA-binding transcription factor activity
J4N42_19680	COG3040	lipid binding
J4N42_19700	COG0110	maltose O-acetyltransferase activity
J4N42_19715	COG2814	Major facilitator Superfamily
J4N42_19735	COG1028	Short-chain dehydrogenase reductase Sdr
J4N42_19740	COG0415	Belongs to the DNA photolyase family
J4N42_19745	COG3046	protein related to deoxyribodipyrimidine photolyase
J4N42_19755	COG1280	lysine exporter protein (LysE YggA)
J4N42_19785	COG0583	DNA-binding transcription factor activity
J4N42_19790	COG2015	COG2015, Alkyl sulfatase and related hydrolases
J4N42_19805	COG1929	Belongs to the glycerate kinase type-1 family
J4N42_19810	COG2610	gluconate transmembrane transporter activity
J4N42_19815	COG3835	regulator
J4N42_19820	COG4106	trans-aconitate 2-methyltransferase activity
J4N42_19830	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
J4N42_19835	COG4266	Belongs to the allantoicase family
J4N42_19855	COG2252	PERMEase
J4N42_19915	COG1770	oligopeptidase
J4N42_19925	COG2084	Dehydrogenase
J4N42_19930	COG3622	Belongs to the hyi family
J4N42_19940	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J4N42_19965	COG0366	Alpha amylase catalytic
J4N42_19985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4N42_19990	COG0784	Response regulator, receiver
J4N42_19990	COG0835	chemotaxis
J4N42_20005	COG1429	ligase activity, forming nitrogen-metal bonds
J4N42_20010	COG4771	TonB-dependent receptor
J4N42_20020	COG2315	Protein conserved in bacteria
J4N42_20025	COG1846	Transcriptional regulator
J4N42_20030	COG0697	spore germination
J4N42_20035	COG3706	GGDEF domain
J4N42_20055	COG1760	l-serine dehydratase
J4N42_20060	COG0583	DNA-binding transcription factor activity
J4N42_20090	COG3842	ATPase activity
J4N42_20095	COG1840	ABC-type Fe3 transport system, periplasmic component
J4N42_20100	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J4N42_20105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J4N42_20120	COG1288	antiporter activity
J4N42_20140	COG1011	Hydrolase
J4N42_20150	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
J4N42_20155	COG1454	alcohol dehydrogenase
J4N42_20175	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N42_20180	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N42_20220	COG1028	Short-chain dehydrogenase reductase Sdr
J4N42_20230	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J4N42_20285	COG0393	Putative heavy-metal-binding
J4N42_20295	COG0251	oxidation-reduction process
J4N42_20310	COG0456	acetyltransferase
J4N42_20315	COG0110	maltose O-acetyltransferase activity
J4N42_20370	COG2154	pterin-4-alpha-carbinolamine dehydratase
J4N42_20375	COG3186	Phenylalanine-4-hydroxylase
J4N42_20380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J4N42_20385	COG2226	methyltransferase
J4N42_20400	COG2962	Rard protein
J4N42_20420	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J4N42_20430	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J4N42_20435	COG0509	glycine decarboxylation via glycine cleavage system
J4N42_20460	COG1132	(ABC) transporter
J4N42_20465	COG2188	Transcriptional regulator
J4N42_20470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N42_20470	COG1263	PTS System
J4N42_20475	COG1621	beta-fructofuranosidase activity
J4N42_20485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N42_20505	COG0583	DNA-binding transcription factor activity
J4N42_20515	COG0583	DNA-binding transcription factor activity
J4N42_20520	COG3048	D-serine ammonia-lyase activity
J4N42_20530	COG3153	acetyltransferase
J4N42_20540	COG1733	regulation of RNA biosynthetic process
J4N42_20550	COG4221	oxidoreductase activity
J4N42_20565	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J4N42_20580	COG0784	Response regulator, receiver
J4N42_20580	COG2205	protein histidine kinase activity
J4N42_20580	COG5002	protein histidine kinase activity
J4N42_20585	COG2176	DNA-directed DNA polymerase activity
J4N42_20590	COG0513	Belongs to the DEAD box helicase family
J4N42_20635	COG0800	Aldolase
J4N42_20640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N42_20645	COG4145	pantothenate transmembrane transporter activity
J4N42_20655	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
J4N42_20670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4N42_20675	COG1151	hydroxylamine reductase activity
J4N42_20690	COG2755	lipolytic protein G-D-S-L family
J4N42_20690	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J4N42_20700	COG3833	ABC-type maltose transport systems, permease component
J4N42_20705	COG1175	transmembrane transport
J4N42_20715	COG3842	ATPase activity
J4N42_20720	COG0330	HflC and HflK could
J4N42_20735	COG0748	coenzyme F420 binding
J4N42_20740	COG3721	Heme iron utilization protein
J4N42_20750	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
J4N42_20755	COG0811	peptide transport
J4N42_20760	COG0848	biopolymer transport protein
J4N42_20770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N42_20775	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
J4N42_20815	COG0583	DNA-binding transcription factor activity
J4N42_20830	COG1741	Belongs to the pirin family
J4N42_20835	COG3123	guanosine phosphorylase activity
J4N42_20845	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4N42_20850	COG0569	domain protein
J4N42_20855	COG0668	transmembrane transport
J4N42_20870	COG0840	transmembrane signaling receptor activity
J4N42_20895	COG3829	transcription factor binding
J4N42_20970	COG0583	DNA-binding transcription factor activity
J4N42_20975	COG2814	Major facilitator Superfamily
J4N42_20980	COG1686	Belongs to the peptidase S11 family
J4N42_21000	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
J4N42_21020	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J4N42_21030	COG1228	amidohydrolase
J4N42_21040	COG1765	OsmC-like protein
J4N42_21045	COG0673	inositol 2-dehydrogenase activity
J4N42_21070	COG0531	amino acid
J4N42_21075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4N42_21085	COG0778	Nitroreductase
J4N42_21100	COG4149	molybdate abc transporter
J4N42_21105	COG0725	ABC transporter, periplasmic molybdate-binding protein
J4N42_21110	COG2005	Transcriptional regulator
J4N42_21110	COG3585	molybdate ion transport
J4N42_21130	COG2239	Acts as a magnesium transporter
J4N42_21140	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J4N42_21145	COG0402	S-adenosylhomocysteine deaminase activity
J4N42_21175	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J4N42_21190	COG3206	protein involved in exopolysaccharide biosynthesis
J4N42_21190	COG0489	protein tyrosine kinase activity
J4N42_21195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4N42_21205	COG0438	transferase activity, transferring glycosyl groups
J4N42_21210	COG2244	polysaccharide biosynthetic process
J4N42_21220	COG1215	transferase activity, transferring glycosyl groups
J4N42_21225	COG1215	transferase activity, transferring glycosyl groups
J4N42_21230	COG1215	transferase activity, transferring glycosyl groups
J4N42_21255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N42_21265	COG2197	response regulator
J4N42_21275	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J4N42_21280	COG3246	L-lysine catabolic process to acetate
J4N42_21285	COG2358	TRAP transporter, solute receptor (TAXI family
J4N42_21290	COG0583	DNA-binding transcription factor activity
J4N42_21330	COG0564	pseudouridine synthase activity
J4N42_21335	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4N42_21340	COG0581	inorganic phosphate transmembrane transporter activity
J4N42_21345	COG0573	inorganic phosphate transmembrane transporter activity
J4N42_21355	COG0840	transmembrane signaling receptor activity
J4N42_21360	COG0513	Belongs to the DEAD box helicase family
J4N42_21370	COG1388	LysM domain
J4N42_21370	COG1376	ErfK ybiS ycfS ynhG family protein
J4N42_21375	COG0813	purine-nucleoside phosphorylase activity
J4N42_21405	COG1566	PFAM secretion protein HlyD family protein
J4N42_21420	COG1737	Transcriptional regulator
J4N42_21425	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N42_21430	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J4N42_21435	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J4N42_21440	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
J4N42_21445	COG1940	carbohydrate kinase activity
J4N42_21450	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J4N42_21455	COG0786	glutamate:sodium symporter activity
J4N42_21465	COG2194	sulfuric ester hydrolase activity
J4N42_21475	COG4221	oxidoreductase activity
J4N42_21490	COG0745	RESPONSE REGULATOR receiver
J4N42_21515	COG1823	symporter activity
J4N42_21520	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J4N42_21540	COG1335	isochorismatase
J4N42_21565	COG3033	Beta-eliminating lyase
J4N42_21600	COG1595	DNA-templated transcription, initiation
J4N42_21645	COG1166	arginine decarboxylase activity
J4N42_21650	COG0010	Belongs to the arginase family
J4N42_21655	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J4N42_21660	COG1640	4-alpha-glucanotransferase
J4N42_21665	COG0058	SHG alpha-glucan phosphorylase activity
J4N42_21670	COG2909	trisaccharide binding
J4N42_21675	COG1609	Transcriptional regulator
J4N42_21690	COG2211	Major facilitator Superfamily
J4N42_21695	COG3250	beta-galactosidase activity
J4N42_21730	COG1051	belongs to the nudix hydrolase family
J4N42_21765	COG0384	phenazine biosynthesis protein PhzF
J4N42_21815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N42_21825	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
J4N42_21840	COG0583	DNA-binding transcription factor activity
J4N42_21845	COG2211	Major facilitator Superfamily
J4N42_21870	COG3119	arylsulfatase activity
J4N42_21880	COG0641	radical SAM
J4N42_21895	COG0513	Belongs to the DEAD box helicase family
J4N42_21915	COG2814	Major facilitator Superfamily
J4N42_21925	COG0583	DNA-binding transcription factor activity
J4N42_21935	COG0583	DNA-binding transcription factor activity
J4N42_21940	COG1486	melibiose metabolic process
J4N42_21950	COG0456	acetyltransferase
J4N42_21955	COG3706	GGDEF domain
J4N42_21960	COG4890	Cyd operon protein YbgT
J4N42_21965	COG1294	oxidase, subunit
J4N42_21970	COG1271	oxidase subunit
J4N42_21985	COG3220	belongs to the UPF0276 family
J4N42_22000	COG2188	Transcriptional regulator
J4N42_22005	COG2223	nitrite transmembrane transporter activity
J4N42_22010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N42_22015	COG1397	ADP-ribosylglycohydrolase
J4N42_22020	COG2211	Major facilitator Superfamily
J4N42_22035	COG2015	COG2015, Alkyl sulfatase and related hydrolases
J4N42_22055	COG0583	DNA-binding transcription factor activity
J4N42_22060	COG0745	RESPONSE REGULATOR receiver
J4N42_22065	COG5002	protein histidine kinase activity
J4N42_22075	COG3111	PFAM Bacterial OB fold (BOF) protein
J4N42_22090	COG3321	synthase
J4N42_22090	COG1028	Short-chain dehydrogenase reductase Sdr
J4N42_22090	COG0604	alcohol dehydrogenase
J4N42_22095	COG4604	ABC transporter, ATP-binding protein
J4N42_22100	COG4605	iron ion homeostasis
J4N42_22105	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N42_22110	COG4607	ABC-type enterochelin transport system periplasmic component
J4N42_22120	COG4771	TonB-dependent receptor
J4N42_22125	COG3214	Protein conserved in bacteria
J4N42_22130	COG2814	Major facilitator Superfamily
J4N42_22145	COG0800	Aldolase
J4N42_22150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N42_22155	COG2190	(PTS) system
J4N42_22155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N42_22155	COG1263	PTS System
J4N42_22165	COG2188	Transcriptional regulator
J4N42_22170	COG1028	Short-chain dehydrogenase reductase Sdr
J4N42_22185	COG1609	Transcriptional regulator
J4N42_22210	COG1760	l-serine dehydratase
J4N42_22230	COG1288	antiporter activity
J4N42_22240	COG1802	Transcriptional regulator
J4N42_22245	COG2205	protein histidine kinase activity
J4N42_22245	COG0784	Response regulator, receiver
J4N42_22255	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J4N42_22260	COG1072	(Pantothenic acid kinase))
J4N42_22270	COG1063	alcohol dehydrogenase
J4N42_22275	COG2213	PTS system mannitol-specific
J4N42_22280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N42_22290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N42_22290	COG1263	PTS System
J4N42_22295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J4N42_22305	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J4N42_22315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N42_22320	COG1454	alcohol dehydrogenase
J4N42_22330	COG0561	phosphatase activity
J4N42_22370	COG1473	amidohydrolase
J4N42_22375	COG0729	surface antigen
J4N42_22380	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
J4N42_22390	COG0583	DNA-binding transcription factor activity
J4N42_22395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4N42_22415	COG1566	PFAM secretion protein HlyD family protein
J4N42_22425	COG2272	Belongs to the type-B carboxylesterase lipase family
J4N42_22435	COG2860	membrane
J4N42_22450	COG0405	Gamma-glutamyltransferase
J4N42_22455	COG1357	PFAM Pentapeptide repeats (8 copies)
J4N42_22465	COG0348	domain, Protein
J4N42_22470	COG0437	4 iron, 4 sulfur cluster binding
J4N42_22475	COG1280	lysine exporter protein (LysE YggA)
J4N42_22480	COG0583	DNA-binding transcription factor activity
J4N42_22505	COG2084	Dehydrogenase
J4N42_22535	COG0444	Belongs to the ABC transporter superfamily
J4N42_22540	COG4608	Belongs to the ABC transporter superfamily