locus-tag	class	description
J4N41_00010	COG0592	DNA-directed DNA polymerase activity
J4N41_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J4N41_00020	COG0187	DNA topoisomerase II activity
J4N41_00030	COG3977	Valine--pyruvate aminotransferase
J4N41_00040	COG0752	glycyl-tRNA synthetase alpha subunit
J4N41_00045	COG2119	membrane
J4N41_00055	COG0425	Belongs to the sulfur carrier protein TusA family
J4N41_00070	COG0604	alcohol dehydrogenase
J4N41_00080	COG0129	dihydroxy-acid dehydratase activity
J4N41_00085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J4N41_00090	COG3978	acetolactate synthase activity
J4N41_00100	COG0606	chelatase, subunit chli
J4N41_00135	COG0464	growth
J4N41_00140	COG1061	Type III restriction enzyme res subunit
J4N41_00205	COG0204	Acyl-transferase
J4N41_00210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4N41_00215	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J4N41_00225	COG3084	Protein conserved in bacteria
J4N41_00235	COG4326	sporulation control protein
J4N41_00240	COG1272	protein, Hemolysin III
J4N41_00250	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4N41_00255	COG0569	domain protein
J4N41_00260	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J4N41_00260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J4N41_00275	COG0758	DNA mediated transformation
J4N41_00280	COG2922	Belongs to the Smg family
J4N41_00285	COG0551	DNA topoisomerase type I activity
J4N41_00290	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J4N41_00295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J4N41_00305	COG0408	coproporphyrinogen oxidase activity
J4N41_00320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J4N41_00385	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J4N41_00390	COG3300	MHYT domain
J4N41_00390	COG5001	Diguanylate cyclase
J4N41_00400	COG3852	Histidine kinase
J4N41_00405	COG0174	glutamine synthetase
J4N41_00410	COG1217	gtp-binding protein TYPA
J4N41_00425	COG1295	ribonuclease BN
J4N41_00430	COG1490	D-aminoacyl-tRNA deacylase activity
J4N41_00435	COG0456	acetyltransferase
J4N41_00445	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
J4N41_00450	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
J4N41_00455	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J4N41_00460	COG3031	protein transport across the cell outer membrane
J4N41_00470	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4N41_00475	COG1459	type II secretion system
J4N41_00480	COG2165	general secretion pathway protein
J4N41_00485	COG2165	general secretion pathway protein
J4N41_00490	COG2165	general secretion pathway protein
J4N41_00495	COG4795	General secretion pathway protein
J4N41_00500	COG3156	type II secretion system protein K
J4N41_00505	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
J4N41_00510	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
J4N41_00530	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4N41_00540	COG2183	response to ionizing radiation
J4N41_00555	COG1040	competence protein
J4N41_00565	COG0494	nUDIX hydrolase
J4N41_00570	COG1218	3'(2'),5'-bisphosphate nucleotidase
J4N41_00575	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J4N41_00580	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J4N41_00585	COG1561	YicC-like family, N-terminal region
J4N41_00590	COG2252	PERMEase
J4N41_00595	COG0194	GDP metabolic process
J4N41_00600	COG1758	RNA polymerase activity
J4N41_00605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J4N41_00610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4N41_00615	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J4N41_00620	COG1560	Kdo2-lipid A biosynthetic process
J4N41_00625	COG1560	Kdo2-lipid A biosynthetic process
J4N41_00630	COG1309	transcriptional regulator
J4N41_00640	COG2003	Belongs to the UPF0758 family
J4N41_00645	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J4N41_00665	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
J4N41_00670	COG0859	PFAM glycosyl transferase family 9
J4N41_00675	COG0463	Glycosyl transferase, family 2
J4N41_00680	COG0859	PFAM glycosyl transferase family 9
J4N41_00685	COG3642	lipopolysaccharide core region biosynthetic process
J4N41_00735	COG1519	Transferase
J4N41_00750	COG0859	PFAM glycosyl transferase family 9
J4N41_00765	COG3307	-O-antigen
J4N41_00795	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J4N41_00810	COG1132	(ABC) transporter
J4N41_00815	COG1086	Polysaccharide biosynthesis protein
J4N41_00820	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J4N41_00825	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J4N41_00830	COG2089	acid synthase
J4N41_00850	COG1083	cytidylyl-transferase
J4N41_00885	COG1215	transferase activity, transferring glycosyl groups
J4N41_00900	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J4N41_00905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4N41_00910	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
J4N41_00910	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
J4N41_00915	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J4N41_00955	COG1494	fructose-1,6-bisphosphatase
J4N41_00960	COG3074	FtsZ-dependent cytokinesis
J4N41_00965	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J4N41_00970	COG0460	homoserine dehydrogenase
J4N41_00970	COG0527	aspartate kinase activity
J4N41_00975	COG0626	cystathionine gamma-synthase activity
J4N41_00980	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
J4N41_00985	COG0281	malic enzyme
J4N41_00995	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J4N41_01000	COG1609	Transcriptional regulator
J4N41_01005	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J4N41_01010	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
J4N41_01030	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
J4N41_01035	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J4N41_01040	COG1053	succinate dehydrogenase
J4N41_01045	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
J4N41_01050	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N41_01085	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4N41_01100	COG1045	serine acetyltransferase
J4N41_01105	COG1695	Transcriptional regulator
J4N41_01110	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
J4N41_01115	COG1573	uracil-dna glycosylase
J4N41_01120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4N41_01130	COG1253	flavin adenine dinucleotide binding
J4N41_01145	COG0151	Belongs to the GarS family
J4N41_01150	COG0138	bifunctional purine biosynthesis protein purh
J4N41_01155	COG0789	Transcriptional regulator
J4N41_01160	COG2199	diguanylate cyclase activity
J4N41_01165	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
J4N41_01170	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4N41_01175	COG2264	protein methyltransferase activity
J4N41_01180	COG0439	Biotin carboxylase
J4N41_01185	COG0511	ligase activity, forming carbon-carbon bonds
J4N41_01190	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J4N41_01195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J4N41_01210	COG2814	Major facilitator Superfamily
J4N41_01215	COG2205	protein histidine kinase activity
J4N41_01215	COG0784	Response regulator, receiver
J4N41_01220	COG1072	(Pantothenic acid kinase))
J4N41_01245	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J4N41_01250	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J4N41_01255	COG0250	Participates in transcription elongation, termination and antitermination
J4N41_01270	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J4N41_01280	COG0085	RNA polymerase activity
J4N41_01285	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J4N41_01290	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J4N41_01295	COG1027	Aspartate ammonia-lyase
J4N41_01370	COG0512	Glutamine amidotransferase of anthranilate synthase
J4N41_01375	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J4N41_01385	COG1012	belongs to the aldehyde dehydrogenase family
J4N41_01395	COG0688	phosphatidylethanolamine metabolic process
J4N41_01400	COG1162	GTPase activity
J4N41_01455	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J4N41_01460	COG0802	atpase or kinase
J4N41_01465	COG0860	N-Acetylmuramoyl-L-alanine amidase
J4N41_01470	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J4N41_01485	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J4N41_01490	COG0330	HflC and HflK could
J4N41_01495	COG0330	HflC and HflK could
J4N41_01500	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
J4N41_01505	COG2900	Belongs to the SlyX family
J4N41_01515	COG0545	Peptidyl-prolyl cis-trans isomerase
J4N41_01520	COG2964	Protein conserved in bacteria
J4N41_01525	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
J4N41_01530	COG2923	Belongs to the DsrF TusC family
J4N41_01535	COG2168	tRNA wobble position uridine thiolation
J4N41_01545	COG0049	tRNA binding
J4N41_01550	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J4N41_01555	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J4N41_01560	COG2906	2 iron, 2 sulfur cluster binding
J4N41_01570	COG0360	Binds together with S18 to 16S ribosomal RNA
J4N41_01590	COG0305	Participates in initiation and elongation during chromosome replication
J4N41_01595	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J4N41_01600	COG0432	Pfam Uncharacterised protein family UPF0047
J4N41_01625	COG1136	(ABC) transporter
J4N41_01640	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
J4N41_01650	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N41_01655	COG0729	surface antigen
J4N41_01660	COG2911	Protein conserved in bacteria
J4N41_01665	COG2105	PFAM AIG2 family protein
J4N41_01670	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J4N41_01680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J4N41_01685	COG0163	prenyltransferase activity
J4N41_01690	COG4143	(ABC) transporter
J4N41_01695	COG1178	ABC-type Fe3 transport system permease component
J4N41_01700	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
J4N41_01710	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J4N41_01725	COG0629	single-stranded DNA binding
J4N41_01730	COG2199	diguanylate cyclase activity
J4N41_01730	COG2200	EAL domain
J4N41_01755	COG3267	Type II secretory pathway component ExeA
J4N41_01755	COG3409	Peptidoglycan-binding domain 1 protein
J4N41_01765	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4N41_01770	COG1459	type II secretion system
J4N41_01780	COG2165	general secretion pathway protein
J4N41_01785	COG2165	general secretion pathway protein
J4N41_01815	COG1077	Cell shape determining protein MreB Mrl
J4N41_01820	COG1792	Involved in formation and maintenance of cell shape
J4N41_01825	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
J4N41_01830	COG0424	maF-like protein
J4N41_01840	COG3164	Protein of unknown function
J4N41_01845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J4N41_01850	COG0312	modulator of DNA gyrase
J4N41_01905	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
J4N41_01915	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J4N41_01920	COG2066	Belongs to the glutaminase family
J4N41_01925	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J4N41_01930	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J4N41_01965	COG0762	integral membrane protein
J4N41_01970	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J4N41_01975	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J4N41_01990	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J4N41_01995	COG1678	Uncharacterized ACR, COG1678
J4N41_02000	COG0189	ligase activity
J4N41_02005	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J4N41_02010	COG2356	endonuclease I
J4N41_02015	COG3091	SprT-like family
J4N41_02025	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J4N41_02035	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J4N41_02045	COG0191	fructose-bisphosphate aldolase activity
J4N41_02050	COG0668	transmembrane transport
J4N41_02065	COG0583	DNA-binding transcription factor activity
J4N41_02075	COG3706	GGDEF domain
J4N41_02085	COG0469	pyruvate kinase activity
J4N41_02090	COG1349	DNA-binding transcription factor activity
J4N41_02095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J4N41_02110	COG0473	3-isopropylmalate dehydrogenase activity
J4N41_02115	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J4N41_02130	COG0583	DNA-binding transcription factor activity
J4N41_02135	COG1022	Amp-dependent synthetase and ligase
J4N41_02140	COG0028	Belongs to the TPP enzyme family
J4N41_02145	COG0440	acetolactate synthase activity
J4N41_02150	COG0584	glycerophosphoryl diester phosphodiesterase
J4N41_02155	COG2271	Major facilitator Superfamily
J4N41_02160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4N41_02170	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J4N41_02185	COG3079	Belongs to the UPF0149 family
J4N41_02190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N41_02195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N41_02210	COG0354	folic acid binding
J4N41_02215	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J4N41_02220	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J4N41_02225	COG1595	DNA-templated transcription, initiation
J4N41_02235	COG3026	antisigma factor binding
J4N41_02240	COG3086	response to oxidative stress
J4N41_02245	COG0481	GTPase activity
J4N41_02255	COG0571	ribonuclease III activity
J4N41_02260	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J4N41_02265	COG1381	Involved in DNA repair and RecF pathway recombination
J4N41_02270	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J4N41_02275	COG0736	holo-[acyl-carrier-protein] synthase activity
J4N41_02280	COG4999	Histidine kinase
J4N41_02280	COG3437	response regulator, receiver
J4N41_02280	COG2205	protein histidine kinase activity
J4N41_02280	COG3850	Histidine kinase
J4N41_02285	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J4N41_02290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J4N41_02295	COG3956	TIGRFAM MazG family protein
J4N41_02305	COG0148	phosphopyruvate hydratase activity
J4N41_02310	COG0617	tRNA 3'-terminal CCA addition
J4N41_02315	COG3267	Type II secretory pathway component ExeA
J4N41_02315	COG3409	Peptidoglycan-binding domain 1 protein
J4N41_02325	COG4991	sh3 domain protein
J4N41_02330	COG0306	phosphate transporter
J4N41_02335	COG1392	Phosphate transport regulator
J4N41_02340	COG3025	triphosphatase activity
J4N41_02345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N41_02355	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J4N41_02360	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J4N41_02360	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J4N41_02365	COG0745	RESPONSE REGULATOR receiver
J4N41_02375	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J4N41_02390	COG0083	homoserine kinase activity
J4N41_02395	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J4N41_02400	COG2860	membrane
J4N41_02415	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J4N41_02420	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J4N41_02440	COG0534	Mate efflux family protein
J4N41_02445	COG2204	response regulator
J4N41_02455	COG0667	Aldo Keto reductase
J4N41_02465	COG3066	DNA modification
J4N41_02470	COG0494	nUDIX hydrolase
J4N41_02480	COG0730	response to heat
J4N41_02485	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J4N41_02490	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J4N41_02495	COG1283	sodium-dependent phosphate transmembrane transporter activity
J4N41_02500	COG0583	DNA-binding transcription factor activity
J4N41_02505	COG0640	Transcriptional regulator
J4N41_02510	COG0268	Binds directly to 16S ribosomal RNA
J4N41_02515	COG0728	peptidoglycan biosynthetic process
J4N41_02520	COG0196	riboflavin kinase activity
J4N41_02535	COG1047	Peptidyl-prolyl cis-trans
J4N41_02540	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J4N41_02545	COG1966	Carbon starvation protein
J4N41_02555	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
J4N41_02560	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
J4N41_02565	COG2971	BadF BadG BcrA BcrD
J4N41_02575	COG1737	Transcriptional regulator
J4N41_02585	COG3279	Response regulator of the LytR AlgR family
J4N41_02590	COG3275	phosphorelay sensor kinase activity
J4N41_02595	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4N41_02600	COG0287	Prephenate dehydrogenase
J4N41_02600	COG1605	Chorismate mutase
J4N41_02605	COG0739	heme binding
J4N41_02615	COG0488	(ABC) transporter
J4N41_02620	COG0741	lytic transglycosylase activity
J4N41_02625	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
J4N41_02630	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
J4N41_02635	COG5001	Diguanylate cyclase
J4N41_02640	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J4N41_02645	COG1605	Chorismate mutase
J4N41_02645	COG0077	Prephenate dehydratase
J4N41_02650	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J4N41_02655	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
J4N41_02660	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N41_02665	COG0564	pseudouridine synthase activity
J4N41_02670	COG1496	oxidoreductase activity
J4N41_02675	COG0542	response to heat
J4N41_02720	COG0483	inositol monophosphate 1-phosphatase activity
J4N41_02725	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
J4N41_02735	COG1104	cysteine desulfurase activity
J4N41_02740	COG0822	iron-sulfur transferase activity
J4N41_02755	COG0443	Heat shock 70 kDa protein
J4N41_02760	COG0633	Ferredoxin
J4N41_02765	COG2975	iron-sulfur cluster assembly
J4N41_02780	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J4N41_02785	COG0583	DNA-binding transcription factor activity
J4N41_02795	COG0583	DNA-binding transcription factor activity
J4N41_02800	COG1022	Amp-dependent synthetase and ligase
J4N41_02805	COG2169	Transcriptional regulator
J4N41_02835	COG4964	Belongs to the GSP D family
J4N41_02885	COG2059	Chromate
J4N41_02890	COG0583	DNA-binding transcription factor activity
J4N41_02900	COG2169	Transcriptional regulator
J4N41_02905	COG1486	melibiose metabolic process
J4N41_02910	COG2211	Major facilitator Superfamily
J4N41_02920	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4N41_02925	COG1085	galactose-1-phosphate uridylyltransferase
J4N41_02935	COG2017	converts alpha-aldose to the beta-anomer
J4N41_02940	COG1609	Transcriptional regulator
J4N41_02950	COG2211	Major facilitator Superfamily
J4N41_02975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N41_02975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N41_02975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N41_02985	COG2171	N-acyltransferase activity
J4N41_02990	COG0450	alkyl hydroperoxide reductase
J4N41_02995	COG0583	DNA-binding transcription factor activity
J4N41_03000	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J4N41_03025	COG0517	IMP dehydrogenase activity
J4N41_03030	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J4N41_03040	COG1862	Preprotein translocase
J4N41_03045	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N41_03050	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N41_03070	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J4N41_03075	COG0826	peptidase U32
J4N41_03085	COG0745	RESPONSE REGULATOR receiver
J4N41_03090	COG5002	protein histidine kinase activity
J4N41_03100	COG0248	Ppx GppA phosphatase
J4N41_03105	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J4N41_03115	COG0581	inorganic phosphate transmembrane transporter activity
J4N41_03120	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4N41_03125	COG0704	Plays a role in the regulation of phosphate uptake
J4N41_03145	COG3141	response to X-ray
J4N41_03160	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J4N41_03165	COG1074	ATP-dependent DNA helicase activity
J4N41_03170	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J4N41_03190	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
J4N41_03195	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J4N41_03200	COG2166	iron-sulfur cluster assembly
J4N41_03215	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J4N41_03220	COG0124	histidyl-tRNA synthetase
J4N41_03225	COG2976	Protein conserved in bacteria
J4N41_03230	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N41_03235	COG1160	GTP binding
J4N41_03240	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J4N41_03255	COG0516	GMP reductase activity
J4N41_03255	COG0517	IMP dehydrogenase activity
J4N41_03270	COG1584	GPR1 FUN34 yaaH family protein
J4N41_03275	COG1115	amino acid carrier protein
J4N41_03285	COG0583	DNA-binding transcription factor activity
J4N41_03300	COG0784	Response regulator, receiver
J4N41_03300	COG0835	chemotaxis
J4N41_03305	COG0204	Acyl-transferase
J4N41_03320	COG0527	aspartate kinase activity
J4N41_03325	COG5001	Diguanylate cyclase
J4N41_03325	COG4251	negative regulation of phosphorylation
J4N41_03325	COG3706	GGDEF domain
J4N41_03325	COG2203	Gaf domain
J4N41_03330	COG3706	GGDEF domain
J4N41_03340	COG2239	Acts as a magnesium transporter
J4N41_03345	COG0189	ligase activity
J4N41_03345	COG4067	protein conserved in archaea
J4N41_03350	COG0189	ligase activity
J4N41_03370	COG2867	negative regulation of translational initiation
J4N41_03375	COG2914	Belongs to the UPF0125 (RnfH) family
J4N41_03380	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N41_03385	COG0497	DNA recombination
J4N41_03390	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J4N41_03395	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J4N41_03405	COG0443	Heat shock 70 kDa protein
J4N41_03440	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J4N41_03450	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
J4N41_03455	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J4N41_03455	COG0047	phosphoribosylformylglycinamidine synthase activity
J4N41_03480	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J4N41_03485	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J4N41_03490	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J4N41_03495	COG1187	pseudouridine synthase activity
J4N41_03500	COG2840	Smr protein MutS2
J4N41_03525	COG3104	oligopeptide transport
J4N41_03530	COG0367	asparagine synthase
J4N41_03535	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J4N41_03535	COG4651	solute:proton antiporter activity
J4N41_03540	COG1940	carbohydrate kinase activity
J4N41_03540	COG1846	Transcriptional regulator
J4N41_03545	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J4N41_03550	COG1263	PTS System
J4N41_03550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N41_03550	COG2190	(PTS) system
J4N41_03585	COG0330	HflC and HflK could
J4N41_03590	COG3118	belongs to the thioredoxin family
J4N41_03595	COG0300	oxidoreductase activity
J4N41_03600	COG1090	epimerase
J4N41_03625	COG0622	Phosphoesterase
J4N41_03645	COG3710	Transcriptional regulator
J4N41_03650	COG0326	Molecular chaperone. Has ATPase activity
J4N41_03660	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J4N41_03670	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4N41_03675	COG1611	Belongs to the LOG family
J4N41_03690	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J4N41_03690	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J4N41_03700	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
J4N41_03715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J4N41_03720	COG1393	Belongs to the ArsC family
J4N41_03745	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
J4N41_03755	COG0437	4 iron, 4 sulfur cluster binding
J4N41_03760	COG3301	Polysulphide reductase, NrfD
J4N41_03765	COG1138	Cytochrome C-type biogenesis protein
J4N41_03770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4N41_03775	COG3088	subunit of a heme lyase
J4N41_03775	COG4235	cytochrome complex assembly
J4N41_03785	COG2837	iron assimilation
J4N41_03790	COG2027	D-alanyl-D-alanine carboxypeptidase
J4N41_03800	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J4N41_03805	COG0739	heme binding
J4N41_03820	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N41_03830	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J4N41_03840	COG1516	flagellar protein fliS
J4N41_03860	COG1677	Flagellar hook-basal body complex protein FliE
J4N41_03870	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J4N41_03920	COG1987	bacterial-type flagellum assembly
J4N41_03925	COG1684	flagellar biosynthetic protein fliR
J4N41_03940	COG2890	protein-(glutamine-N5) methyltransferase activity
J4N41_03945	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J4N41_03955	COG2860	membrane
J4N41_03960	COG3101	peptidyl-lysine hydroxylation
J4N41_03985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J4N41_03990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4N41_03995	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J4N41_04005	COG0101	tRNA pseudouridine synthase activity
J4N41_04010	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J4N41_04015	COG0285	dihydrofolate synthase activity
J4N41_04020	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
J4N41_04025	COG1286	toxin biosynthetic process
J4N41_04030	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J4N41_04035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J4N41_04040	COG1121	(ABC) transporter
J4N41_04045	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
J4N41_04050	COG4977	sequence-specific DNA binding
J4N41_04055	COG1918	ferrous iron import across plasma membrane
J4N41_04060	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J4N41_04080	COG3102	Protein conserved in bacteria
J4N41_04085	COG1025	Belongs to the peptidase M16 family
J4N41_04090	COG2062	phosphohistidine phosphatase, SixA
J4N41_04120	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
J4N41_04125	COG2198	Histidine kinase
J4N41_04125	COG0784	Response regulator, receiver
J4N41_04125	COG0643	Histidine kinase
J4N41_04130	COG2201	protein-glutamate methylesterase activity
J4N41_04135	COG1192	Involved in chromosome partitioning
J4N41_04145	COG0835	chemotaxis
J4N41_04155	COG4133	protoheme IX ABC transporter activity
J4N41_04160	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4N41_04165	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4N41_04170	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4N41_04180	COG1138	Cytochrome C-type biogenesis protein
J4N41_04185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4N41_04200	COG2853	Lipoprotein
J4N41_04205	COG2067	long-chain fatty acid transport protein
J4N41_04210	COG2067	long-chain fatty acid transport protein
J4N41_04225	COG0183	Belongs to the thiolase family
J4N41_04235	COG0778	Nitroreductase
J4N41_04240	COG0583	DNA-binding transcription factor activity
J4N41_04245	COG0745	RESPONSE REGULATOR receiver
J4N41_04250	COG2832	Protein of unknown function (DUF454)
J4N41_04255	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J4N41_04270	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J4N41_04275	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J4N41_04300	COG1653	transport
J4N41_04305	COG1175	transmembrane transport
J4N41_04315	COG3842	ATPase activity
J4N41_04320	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J4N41_04325	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J4N41_04330	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N41_04340	COG2204	response regulator
J4N41_04360	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J4N41_04365	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J4N41_04370	COG0776	regulation of translation
J4N41_04375	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4N41_04380	COG1555	photosystem II stabilization
J4N41_04385	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J4N41_04390	COG0539	negative regulation of cytoplasmic translation
J4N41_04400	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
J4N41_04405	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
J4N41_04410	COG0284	orotidine-5'-phosphate decarboxylase activity
J4N41_04440	COG4120	Belongs to the binding-protein-dependent transport system permease family
J4N41_04450	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4N41_04465	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J4N41_04470	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J4N41_04475	COG0252	asparaginase activity
J4N41_04480	COG0616	signal peptide processing
J4N41_04485	COG1902	pentaerythritol trinitrate reductase activity
J4N41_04485	COG0446	pyridine nucleotide-disulphide oxidoreductase
J4N41_04490	COG0788	formyltetrahydrofolate deformylase activity
J4N41_04500	COG1199	ATP-dependent helicase activity
J4N41_04505	COG1214	PFAM Peptidase M22, glycoprotease
J4N41_04520	COG0596	Alpha beta hydrolase
J4N41_04525	COG0318	PFAM AMP-dependent synthetase and ligase
J4N41_04530	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
J4N41_04535	COG0659	secondary active sulfate transmembrane transporter activity
J4N41_04540	COG1530	ribonuclease E activity
J4N41_04545	COG0564	pseudouridine synthase activity
J4N41_04555	COG1399	metal-binding, possibly nucleic acid-binding protein
J4N41_04560	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J4N41_04570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J4N41_04595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J4N41_04600	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J4N41_04605	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J4N41_04610	COG0470	DNA polymerase III
J4N41_04615	COG0084	hydrolase, TatD family'
J4N41_04620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N41_04620	COG1263	PTS System
J4N41_04635	COG0733	neurotransmitter:sodium symporter activity
J4N41_04650	COG4667	esterase of the alpha-beta hydrolase superfamily
J4N41_04655	COG0702	epimerase
J4N41_04675	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J4N41_04680	COG0840	transmembrane signaling receptor activity
J4N41_04685	COG0632	four-way junction helicase activity
J4N41_04690	COG2255	four-way junction helicase activity
J4N41_04695	COG1271	oxidase subunit
J4N41_04700	COG1294	oxidase, subunit
J4N41_04705	COG4890	Cyd operon protein YbgT
J4N41_04715	COG0824	Thioesterase
J4N41_04720	COG0811	peptide transport
J4N41_04735	COG0823	Involved in the tonB-independent uptake of proteins
J4N41_04740	COG2885	chlorophyll binding
J4N41_04745	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
J4N41_04750	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J4N41_04765	COG2205	protein histidine kinase activity
J4N41_04765	COG0784	Response regulator, receiver
J4N41_04780	COG1401	restriction endodeoxyribonuclease activity
J4N41_04800	COG1902	pentaerythritol trinitrate reductase activity
J4N41_04805	COG1881	PFAM PEBP family protein
J4N41_04820	COG1940	carbohydrate kinase activity
J4N41_04840	COG1960	acyl-CoA dehydrogenase activity
J4N41_04845	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J4N41_04855	COG0708	Exodeoxyribonuclease III
J4N41_04860	COG0840	transmembrane signaling receptor activity
J4N41_04865	COG2850	peptidyl-arginine hydroxylation
J4N41_04880	COG0730	response to heat
J4N41_04885	COG1199	ATP-dependent helicase activity
J4N41_04900	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J4N41_04910	COG0156	8-amino-7-oxononanoate synthase activity
J4N41_04915	COG2226	methyltransferase
J4N41_04915	COG1073	alpha beta
J4N41_04920	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J4N41_04930	COG0501	Belongs to the peptidase M48B family
J4N41_04940	COG1028	Short-chain dehydrogenase reductase Sdr
J4N41_04955	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J4N41_04965	COG2268	Band 7 protein
J4N41_04975	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J4N41_04985	COG0482	sulfurtransferase activity
J4N41_04995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N41_05005	COG1757	Na H antiporter
J4N41_05015	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J4N41_05025	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J4N41_05025	COG0131	Imidazoleglycerol-phosphate dehydratase
J4N41_05030	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J4N41_05035	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J4N41_05045	COG0140	phosphoribosyl-ATP diphosphatase activity
J4N41_05045	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J4N41_05050	COG2202	Pas domain
J4N41_05050	COG2200	EAL domain
J4N41_05050	COG2199	diguanylate cyclase activity
J4N41_05055	COG2205	protein histidine kinase activity
J4N41_05055	COG0784	Response regulator, receiver
J4N41_05075	COG1227	inorganic diphosphatase activity
J4N41_05085	COG4172	Belongs to the ABC transporter superfamily
J4N41_05095	COG4171	peptide transport system, permease
J4N41_05110	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
J4N41_05115	COG1842	Phage shock protein A
J4N41_05145	COG2818	Glycosylase
J4N41_05155	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J4N41_05160	COG0626	cystathionine gamma-synthase activity
J4N41_05170	COG0733	neurotransmitter:sodium symporter activity
J4N41_05175	COG0564	pseudouridine synthase activity
J4N41_05180	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J4N41_05190	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J4N41_05195	COG4136	ATPase activity
J4N41_05200	COG4135	transport system, permease component
J4N41_05205	COG4134	Bacterial extracellular solute-binding protein
J4N41_05215	COG3313	Fe-S protein
J4N41_05230	COG2350	Protein conserved in bacteria
J4N41_05265	COG0776	regulation of translation
J4N41_05275	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J4N41_05285	COG0417	DNA replication proofreading
J4N41_05300	COG2197	response regulator
J4N41_05305	COG0322	excinuclease ABC activity
J4N41_05335	COG1902	pentaerythritol trinitrate reductase activity
J4N41_05345	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J4N41_05355	COG1032	radical SAM domain protein
J4N41_05380	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J4N41_05390	COG1764	response to oxidative stress
J4N41_05395	COG1846	Transcriptional regulator
J4N41_05405	COG0583	DNA-binding transcription factor activity
J4N41_05430	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J4N41_05480	COG0443	Heat shock 70 kDa protein
J4N41_05520	COG1643	Atp-dependent helicase
J4N41_05535	COG0159	tryptophan synthase activity
J4N41_05545	COG0134	indole-3-glycerol-phosphate synthase activity
J4N41_05545	COG0135	phosphoribosylanthranilate isomerase activity
J4N41_05550	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J4N41_05555	COG0512	Glutamine amidotransferase of anthranilate synthase
J4N41_05560	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J4N41_05570	COG0613	PHP domain protein
J4N41_05575	COG0009	L-threonylcarbamoyladenylate synthase
J4N41_05590	COG1187	pseudouridine synthase activity
J4N41_05595	COG0384	phenazine biosynthesis protein PhzF
J4N41_05600	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J4N41_05605	COG4988	ABC transporter
J4N41_05610	COG0492	ferredoxin-NADP+ reductase activity
J4N41_05625	COG0612	Peptidase, M16
J4N41_05635	COG2949	membrane
J4N41_05645	COG0281	malic enzyme
J4N41_05650	COG1643	Atp-dependent helicase
J4N41_05665	COG1448	Aminotransferase
J4N41_05670	COG3437	response regulator, receiver
J4N41_05670	COG2770	Histidine kinase
J4N41_05680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N41_05690	COG0017	Asparaginyl-tRNA synthetase
J4N41_05695	COG0840	transmembrane signaling receptor activity
J4N41_05700	COG0720	synthase
J4N41_05705	COG0814	amino acid
J4N41_05715	COG1760	l-serine dehydratase
J4N41_05720	COG0814	amino acid
J4N41_05725	COG0494	nUDIX hydrolase
J4N41_05740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J4N41_05755	COG3106	COG3106 Predicted ATPase
J4N41_05770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N41_05800	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J4N41_05825	COG2989	Protein conserved in bacteria
J4N41_05830	COG3108	Peptidase M15
J4N41_05835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4N41_05850	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J4N41_05880	COG0783	Belongs to the Dps family
J4N41_05890	COG0531	amino acid
J4N41_05895	COG2962	Rard protein
J4N41_05920	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J4N41_05930	COG1942	4-Oxalocrotonate Tautomerase
J4N41_06020	COG0346	lactoylglutathione lyase activity
J4N41_06170	COG0251	oxidation-reduction process
J4N41_06205	COG1028	Short-chain dehydrogenase reductase Sdr
J4N41_06270	COG4628	conserved protein (DUF2132)
J4N41_06480	COG3385	transposase activity
J4N41_06620	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J4N41_06665	COG3755	Protein conserved in bacteria
J4N41_06750	COG3385	transposase activity
J4N41_06775	COG1280	lysine exporter protein (LysE YggA)
J4N41_06780	COG2161	toxin-antitoxin pair type II binding
J4N41_06785	COG4115	mRNA cleavage
J4N41_06805	COG0384	phenazine biosynthesis protein PhzF
J4N41_06885	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
J4N41_06895	COG0625	glutathione transferase activity
J4N41_06910	COG2885	chlorophyll binding
J4N41_06925	COG0247	lactate metabolic process
J4N41_06925	COG0277	FAD linked oxidase domain protein
J4N41_06940	COG2986	histidine ammonia-lyase
J4N41_06950	COG0010	Belongs to the arginase family
J4N41_06955	COG1228	amidohydrolase
J4N41_06960	COG2188	Transcriptional regulator
J4N41_06965	COG4326	sporulation control protein
J4N41_06985	COG0500	methyltransferase
J4N41_06990	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J4N41_07000	COG0295	cytidine deaminase activity
J4N41_07005	COG1346	cytolysis
J4N41_07010	COG1380	Effector of murein hydrolase LrgA
J4N41_07015	COG2925	Exonuclease
J4N41_07020	COG1823	symporter activity
J4N41_07025	COG0702	epimerase
J4N41_07030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J4N41_07035	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J4N41_07040	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J4N41_07060	COG4139	cobalamin transport
J4N41_07065	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
J4N41_07090	COG0583	DNA-binding transcription factor activity
J4N41_07095	COG1119	ATPase activity
J4N41_07105	COG2205	protein histidine kinase activity
J4N41_07105	COG0784	Response regulator, receiver
J4N41_07115	COG1451	nucleotide metabolic process
J4N41_07135	COG0596	Alpha beta hydrolase
J4N41_07135	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4N41_07140	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
J4N41_07155	COG2200	EAL domain
J4N41_07170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N41_07195	COG0515	serine threonine protein kinase
J4N41_07310	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
J4N41_07315	COG0372	Belongs to the citrate synthase family
J4N41_07325	COG2828	Protein conserved in bacteria
J4N41_07345	COG0561	phosphatase activity
J4N41_07350	COG0602	queuosine metabolic process
J4N41_07385	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J4N41_07390	COG0840	transmembrane signaling receptor activity
J4N41_07395	COG1254	Belongs to the acylphosphatase family
J4N41_07400	COG2920	part of a sulfur-relay system
J4N41_07405	COG0670	Belongs to the BI1 family
J4N41_07410	COG1126	abc transporter atp-binding protein
J4N41_07415	COG0765	amino acid transport
J4N41_07420	COG4597	amino acid ABC transporter
J4N41_07425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N41_07430	COG1648	precorrin-2 dehydrogenase activity
J4N41_07430	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J4N41_07440	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4N41_07445	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J4N41_07465	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
J4N41_07465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J4N41_07470	COG3008	intermembrane lipid transfer
J4N41_07475	COG2995	paraquat-inducible protein a
J4N41_07480	COG1132	(ABC) transporter
J4N41_07485	COG1956	GAF domain-containing protein
J4N41_07490	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
J4N41_07505	COG0308	aminopeptidase N
J4N41_07520	COG0167	dihydroorotate dehydrogenase activity
J4N41_07530	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J4N41_07530	COG0116	Belongs to the methyltransferase superfamily
J4N41_07540	COG0488	(ABC) transporter
J4N41_07555	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J4N41_07560	COG1067	ATP-dependent peptidase activity
J4N41_07565	COG3120	sequence-specific DNA binding
J4N41_07610	COG0840	transmembrane signaling receptor activity
J4N41_07615	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J4N41_07750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4N41_07765	COG3278	Belongs to the heme-copper respiratory oxidase family
J4N41_07780	COG2010	Cytochrome c
J4N41_07790	COG2217	Heavy metal translocating P-type atpase
J4N41_07805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N41_07810	COG0589	response to stress
J4N41_07835	COG3842	ATPase activity
J4N41_07845	COG1177	transmembrane transport
J4N41_07850	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J4N41_07860	COG2199	diguanylate cyclase activity
J4N41_07865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J4N41_07880	COG0583	DNA-binding transcription factor activity
J4N41_07895	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
J4N41_07925	COG0488	(ABC) transporter
J4N41_07935	COG1595	DNA-templated transcription, initiation
J4N41_07945	COG1910	domain protein
J4N41_07950	COG0746	molybdenum cofactor guanylyltransferase activity
J4N41_07955	COG1763	Mo-molybdopterin cofactor biosynthetic process
J4N41_07985	COG1940	carbohydrate kinase activity
J4N41_07990	COG3148	PFAM DTW domain containing protein
J4N41_08000	COG3290	protein histidine kinase activity
J4N41_08000	COG0840	transmembrane signaling receptor activity
J4N41_08005	COG0791	NLP P60 protein
J4N41_08015	COG3001	Fructosamine kinase
J4N41_08025	COG0307	riboflavin synthase, alpha
J4N41_08030	COG0534	Mate efflux family protein
J4N41_08075	COG2204	response regulator
J4N41_08085	COG0438	transferase activity, transferring glycosyl groups
J4N41_08120	COG0297	glycogen (starch) synthase activity
J4N41_08130	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J4N41_08150	COG1196	nuclear chromosome segregation
J4N41_08165	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
J4N41_08210	COG3293	Transposase
J4N41_08240	COG4774	siderophore transport
J4N41_08260	COG4615	Cyclic peptide transporter
J4N41_08270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4N41_08275	COG1120	ATPase activity
J4N41_08280	COG2977	Belongs to the P-Pant transferase superfamily
J4N41_08285	COG1929	Belongs to the glycerate kinase type-1 family
J4N41_08290	COG3835	regulator
J4N41_08295	COG0583	DNA-binding transcription factor activity
J4N41_08305	COG3385	transposase activity
J4N41_08310	COG3713	MltA-interacting MipA family protein
J4N41_08315	COG2205	protein histidine kinase activity
J4N41_08320	COG0745	RESPONSE REGULATOR receiver
J4N41_08340	COG2116	formate transmembrane transporter activity
J4N41_08350	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4N41_08355	COG2199	diguanylate cyclase activity
J4N41_08360	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4N41_08385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N41_08390	COG0454	-acetyltransferase
J4N41_08435	COG3122	Protein conserved in bacteria
J4N41_08455	COG4565	transcriptional regulatory protein
J4N41_08460	COG3290	protein histidine kinase activity
J4N41_08480	COG0848	biopolymer transport protein
J4N41_08485	COG0811	peptide transport
J4N41_08490	COG0811	peptide transport
J4N41_08525	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J4N41_08530	COG1328	CTP reductase activity
J4N41_08535	COG0840	transmembrane signaling receptor activity
J4N41_08545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4N41_08550	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4N41_08555	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4N41_08560	COG0633	Ferredoxin
J4N41_08585	COG0019	diaminopimelate decarboxylase activity
J4N41_08610	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J4N41_08620	COG0577	efflux transmembrane transporter activity
J4N41_08625	COG1136	(ABC) transporter
J4N41_08630	COG0534	Mate efflux family protein
J4N41_08635	COG0702	epimerase
J4N41_08645	COG2814	Major facilitator Superfamily
J4N41_08655	COG1061	Type III restriction enzyme res subunit
J4N41_08695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N41_08700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N41_08715	COG0463	Glycosyl transferase, family 2
J4N41_08765	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J4N41_08815	COG0242	peptide deformylase activity
J4N41_08820	COG0519	Catalyzes the synthesis of GMP from XMP
J4N41_08830	COG4580	involved in the transport of maltose and maltodextrins
J4N41_08835	COG3040	lipid binding
J4N41_08845	COG2824	Alkylphosphonate utilization operon protein PhnA
J4N41_08900	COG1115	amino acid carrier protein
J4N41_08905	COG1280	lysine exporter protein (LysE YggA)
J4N41_08910	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
J4N41_08915	COG0352	thiamine-phosphate diphosphorylase activity
J4N41_08930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N41_08940	COG1012	belongs to the aldehyde dehydrogenase family
J4N41_08950	COG0583	DNA-binding transcription factor activity
J4N41_08970	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J4N41_08980	COG1609	Transcriptional regulator
J4N41_08985	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J4N41_08995	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J4N41_08995	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N41_09010	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N41_09015	COG1609	Transcriptional regulator
J4N41_09030	COG1278	Cold shock
J4N41_09055	COG1538	Outer membrane efflux protein
J4N41_09060	COG1858	cytochrome C peroxidase
J4N41_09065	COG2205	protein histidine kinase activity
J4N41_09065	COG0784	Response regulator, receiver
J4N41_09080	COG0277	FAD linked oxidase domain protein
J4N41_09085	COG0583	DNA-binding transcription factor activity
J4N41_09105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N41_09145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4N41_09145	COG0072	phenylalanine-tRNA ligase activity
J4N41_09175	COG2133	pyrroloquinoline quinone binding
J4N41_09185	COG4191	Histidine kinase
J4N41_09200	COG3070	regulator of competence-specific genes
J4N41_09210	COG2431	L-lysine efflux transmembrane transporter activity
J4N41_09220	COG0076	glutamate decarboxylase activity
J4N41_09225	COG1737	Transcriptional regulator
J4N41_09230	COG1454	alcohol dehydrogenase
J4N41_09230	COG1012	belongs to the aldehyde dehydrogenase family
J4N41_09235	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J4N41_09270	COG1882	Formate acetyltransferase
J4N41_09285	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J4N41_09295	COG3013	Belongs to the UPF0304 family
J4N41_09300	COG2766	serine protein kinase
J4N41_09305	COG2718	Belongs to the UPF0229 family
J4N41_09310	COG2719	SpoVR family
J4N41_09315	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J4N41_09320	COG2835	tetraacyldisaccharide 4'-kinase activity
J4N41_09330	COG1132	(ABC) transporter
J4N41_09335	COG0658	competence protein
J4N41_09335	COG2333	competence protein COMEC
J4N41_09345	COG4591	ABC-type transport system involved in lipoprotein release permease component
J4N41_09350	COG1136	(ABC) transporter
J4N41_09355	COG4591	ABC-type transport system involved in lipoprotein release permease component
J4N41_09365	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J4N41_09380	COG1252	NADH dehydrogenase
J4N41_09385	COG3150	esterase
J4N41_09410	COG0537	adenosine 5'-monophosphoramidase activity
J4N41_09425	COG2186	Transcriptional regulator
J4N41_09430	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J4N41_09440	COG1674	ftsk spoiiie
J4N41_09450	COG0686	Belongs to the AlaDH PNT family
J4N41_09455	COG3092	negative regulation of chromosome organization
J4N41_09460	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J4N41_09465	COG0857	belongs to the CobB CobQ family
J4N41_09465	COG0280	phosphate acetyltransferase
J4N41_09470	COG0435	Glutathione S-transferase
J4N41_09480	COG0444	Belongs to the ABC transporter superfamily
J4N41_09485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N41_09490	COG0601	transmembrane transport
J4N41_09505	COG2067	long-chain fatty acid transport protein
J4N41_09515	COG0840	transmembrane signaling receptor activity
J4N41_09525	COG1404	Belongs to the peptidase S8 family
J4N41_09530	COG0840	transmembrane signaling receptor activity
J4N41_09555	COG1136	(ABC) transporter
J4N41_09555	COG0577	efflux transmembrane transporter activity
J4N41_09565	COG0577	efflux transmembrane transporter activity
J4N41_09575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N41_09590	COG1770	oligopeptidase
J4N41_09680	COG3706	GGDEF domain
J4N41_09695	COG3126	Type III secretion system lipoprotein chaperone (YscW)
J4N41_09700	COG1946	Acyl-CoA thioesterase
J4N41_09705	COG1522	sequence-specific DNA binding
J4N41_09730	COG0477	Major facilitator Superfamily
J4N41_09735	COG2855	membrane
J4N41_09765	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
J4N41_09770	COG1169	isochorismate synthase
J4N41_09775	COG0436	Aminotransferase
J4N41_09780	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
J4N41_09785	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J4N41_09790	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J4N41_09805	COG0513	Belongs to the DEAD box helicase family
J4N41_09815	COG0616	signal peptide processing
J4N41_09820	COG1028	Short-chain dehydrogenase reductase Sdr
J4N41_09825	COG0469	pyruvate kinase activity
J4N41_09830	COG1940	carbohydrate kinase activity
J4N41_09835	COG0835	chemotaxis
J4N41_09835	COG0784	Response regulator, receiver
J4N41_09850	COG0243	molybdopterin cofactor binding
J4N41_09855	COG3005	denitrification pathway
J4N41_09860	COG4459	periplasmic nitrate reductase
J4N41_09865	COG0390	transport system, permease component
J4N41_09875	COG2116	formate transmembrane transporter activity
J4N41_09900	COG0542	response to heat
J4N41_09910	COG1278	Cold shock
J4N41_09920	COG1187	pseudouridine synthase activity
J4N41_09930	COG1801	Protein of unknown function DUF72
J4N41_09940	COG0500	methyltransferase
J4N41_09945	COG0189	ligase activity
J4N41_09945	COG4067	protein conserved in archaea
J4N41_09960	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J4N41_09965	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
J4N41_09975	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4N41_09980	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J4N41_09985	COG0745	RESPONSE REGULATOR receiver
J4N41_10000	COG3070	regulator of competence-specific genes
J4N41_10005	COG3385	transposase activity
J4N41_10025	COG0297	glycogen (starch) synthase activity
J4N41_10030	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J4N41_10035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4N41_10055	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J4N41_10060	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
J4N41_10065	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J4N41_10070	COG1435	thymidine kinase activity
J4N41_10075	COG0215	cysteine-tRNA ligase activity
J4N41_10080	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J4N41_10085	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4N41_10090	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J4N41_10095	COG3012	SEC-C Motif Domain Protein
J4N41_10100	COG3139	Protein of unknown function (DUF1315)
J4N41_10110	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N41_10125	COG2226	methyltransferase
J4N41_10140	COG1785	Belongs to the alkaline phosphatase family
J4N41_10145	COG2771	luxR family
J4N41_10155	COG2814	Major facilitator Superfamily
J4N41_10160	COG1028	Short-chain dehydrogenase reductase Sdr
J4N41_10185	COG2951	lytic endotransglycosylase activity
J4N41_10190	COG3100	YcgL domain-containing protein
J4N41_10195	COG0850	regulation of cytokinetic process
J4N41_10200	COG2894	cell division
J4N41_10205	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
J4N41_10210	COG1454	alcohol dehydrogenase
J4N41_10210	COG1012	belongs to the aldehyde dehydrogenase family
J4N41_10215	COG2095	MarC family integral membrane protein
J4N41_10220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N41_10225	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J4N41_10230	COG1757	Na H antiporter
J4N41_10235	COG2188	Transcriptional regulator
J4N41_10240	COG1263	PTS System
J4N41_10240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N41_10245	COG1621	beta-fructofuranosidase activity
J4N41_10255	COG3081	Nucleoid-associated protein
J4N41_10260	COG3082	Protein of unknown function (DUF1414)
J4N41_10265	COG3083	sulfuric ester hydrolase activity
J4N41_10290	COG0123	including yeast histone deacetylase and acetoin utilization protein
J4N41_10300	COG1881	PFAM PEBP family protein
J4N41_10310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4N41_10315	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J4N41_10335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J4N41_10340	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
J4N41_10380	COG0383	alpha-mannosidase activity
J4N41_10400	COG1940	carbohydrate kinase activity
J4N41_10405	COG2982	Protein involved in outer membrane biogenesis
J4N41_10410	COG0572	uridine kinase
J4N41_10415	COG0489	protein tyrosine kinase activity
J4N41_10420	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4N41_10420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4N41_10450	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J4N41_10450	COG0517	IMP dehydrogenase activity
J4N41_10450	COG0617	tRNA 3'-terminal CCA addition
J4N41_10460	COG3706	GGDEF domain
J4N41_10465	COG0314	molybdopterin synthase activity
J4N41_10470	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J4N41_10475	COG0315	cyclic pyranopterin monophosphate synthase activity
J4N41_10480	COG0521	Mo-molybdopterin cofactor biosynthetic process
J4N41_10485	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J4N41_10490	COG0391	Required for morphogenesis under gluconeogenic growth conditions
J4N41_10495	COG2198	Histidine kinase
J4N41_10505	COG0556	nucleotide-excision repair
J4N41_10530	COG0739	heme binding
J4N41_10595	COG1987	bacterial-type flagellum assembly
J4N41_10620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N41_10625	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J4N41_10630	COG1516	flagellar protein fliS
J4N41_10645	COG1580	Controls the rotational direction of flagella during chemotaxis
J4N41_10650	COG1191	sigma factor activity
J4N41_10655	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J4N41_10660	COG1360	Flagellar Motor Protein
J4N41_10690	COG1706	bacterial-type flagellum-dependent cell motility
J4N41_10695	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J4N41_10700	COG4786	Flagellar basal body rod
J4N41_10705	COG4787	bacterial-type flagellum-dependent cell motility
J4N41_10710	COG1749	Flagellar hook protein flgE
J4N41_10715	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
J4N41_10720	COG1558	bacterial-type flagellum-dependent cell motility
J4N41_10725	COG1815	bacterial-type flagellum-dependent cell motility
J4N41_10745	COG0741	lytic transglycosylase activity
J4N41_10745	COG1388	LysM domain
J4N41_10750	COG4657	Part of a membrane complex involved in electron transport
J4N41_10760	COG4656	Part of a membrane complex involved in electron transport
J4N41_10765	COG4658	electron transport chain
J4N41_10770	COG4659	FMN binding
J4N41_10775	COG4660	Part of a membrane complex involved in electron transport
J4N41_10780	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J4N41_10785	COG0346	lactoylglutathione lyase activity
J4N41_10805	COG2056	Na+-H+ antiporter family
J4N41_10810	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
J4N41_10820	COG2716	regulation of RNA biosynthetic process
J4N41_10825	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J4N41_10845	COG4783	chaperone-mediated protein folding
J4N41_10850	COG1393	Belongs to the ArsC family
J4N41_10870	COG2233	PERMEase
J4N41_10875	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J4N41_10885	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J4N41_10890	COG2912	Transglutaminase-like superfamily
J4N41_10900	COG2890	protein-(glutamine-N5) methyltransferase activity
J4N41_10905	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J4N41_10920	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J4N41_10925	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J4N41_11050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N41_11060	COG1705	Flagellar rod assembly protein muramidase FlgJ
J4N41_11060	COG3951	Flagellar rod assembly protein muramidase FlgJ
J4N41_11065	COG1706	bacterial-type flagellum-dependent cell motility
J4N41_11070	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J4N41_11080	COG4787	bacterial-type flagellum-dependent cell motility
J4N41_11100	COG1815	bacterial-type flagellum-dependent cell motility
J4N41_11105	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J4N41_11110	COG0784	Response regulator, receiver
J4N41_11110	COG0835	chemotaxis
J4N41_11120	COG2747	anti-sigma28 factor FlgM
J4N41_11150	COG0500	methyltransferase
J4N41_11175	COG2217	Heavy metal translocating P-type atpase
J4N41_11175	COG2608	mercury ion transmembrane transporter activity
J4N41_11185	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
J4N41_11200	COG0583	DNA-binding transcription factor activity
J4N41_11205	COG0301	tRNA thio-modification
J4N41_11205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4N41_11215	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J4N41_11220	COG1722	exodeoxyribonuclease VII activity
J4N41_11225	COG0142	geranyltranstransferase activity
J4N41_11235	COG0564	pseudouridine synthase activity
J4N41_11240	COG3098	single-species biofilm formation
J4N41_11255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N41_11275	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4N41_11280	COG0567	Dehydrogenase, E1 component
J4N41_11290	COG1053	succinate dehydrogenase
J4N41_11295	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
J4N41_11310	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J4N41_11320	COG0033	Phosphoglucomutase
J4N41_11325	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
J4N41_11330	COG0596	Alpha beta hydrolase
J4N41_11340	COG0716	FMN binding
J4N41_11345	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J4N41_11350	COG3115	cell septum assembly
J4N41_11355	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
J4N41_11360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J4N41_11365	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N41_11370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J4N41_11375	COG2190	(PTS) system
J4N41_11380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N41_11385	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J4N41_11390	COG1702	phosphate starvation-inducible protein PhoH
J4N41_11395	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J4N41_11400	COG4535	Mg2 and Co2 transporter CorC
J4N41_11405	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J4N41_11410	COG2888	peptidyl-tyrosine sulfation
J4N41_11415	COG0495	leucyl-tRNA aminoacylation
J4N41_11420	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
J4N41_11425	COG1466	dna polymerase III delta subunit
J4N41_11430	COG0799	negative regulation of ribosome biogenesis
J4N41_11435	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J4N41_11440	COG0768	penicillin binding
J4N41_11445	COG0772	Belongs to the SEDS family
J4N41_11450	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J4N41_11455	COG1686	Belongs to the peptidase S11 family
J4N41_11460	COG2921	Belongs to the UPF0250 family
J4N41_11470	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J4N41_11485	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J4N41_11495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N41_11500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N41_11525	COG0366	Alpha amylase catalytic
J4N41_11530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N41_11530	COG1263	PTS System
J4N41_11535	COG1609	Transcriptional regulator
J4N41_11545	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J4N41_11550	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J4N41_11555	COG2011	ABC-type metal ion transport system permease component
J4N41_11560	COG1464	Belongs to the NlpA lipoprotein family
J4N41_11565	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J4N41_11575	COG0254	rRNA binding
J4N41_11580	COG1720	tRNA m6t6A37 methyltransferase activity
J4N41_11590	COG0121	glutamine amidotransferase
J4N41_11595	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J4N41_11600	COG1960	acyl-CoA dehydrogenase activity
J4N41_11615	COG0328	RNA-DNA hybrid ribonuclease activity
J4N41_11620	COG2226	methyltransferase
J4N41_11625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4N41_11630	COG1388	LysM domain
J4N41_11630	COG0741	lytic transglycosylase activity
J4N41_11640	COG3021	interspecies interaction between organisms
J4N41_11645	COG0347	Belongs to the P(II) protein family
J4N41_11660	COG0825	malonyl-CoA metabolic process
J4N41_11665	COG0587	DNA-directed DNA polymerase activity
J4N41_11670	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J4N41_11675	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4N41_11685	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J4N41_11690	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4N41_11695	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
J4N41_11700	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N41_11705	COG0750	zinc metalloprotease
J4N41_11715	COG0575	Belongs to the CDS family
J4N41_11720	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J4N41_11725	COG0233	cytoplasmic translational termination
J4N41_11730	COG0528	UMP kinase activity
J4N41_11740	COG0052	Belongs to the universal ribosomal protein uS2 family
J4N41_11745	COG0024	Methionine aminopeptidase
J4N41_11750	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
J4N41_11760	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J4N41_11765	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J4N41_11770	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J4N41_11790	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4N41_11790	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4N41_11795	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J4N41_11800	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J4N41_11805	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J4N41_11815	COG1073	alpha beta
J4N41_11820	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
J4N41_11825	COG2252	PERMEase
J4N41_11830	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4N41_11835	COG4067	protein conserved in archaea
J4N41_11835	COG0189	ligase activity
J4N41_11840	COG0189	ligase activity
J4N41_11850	COG0733	neurotransmitter:sodium symporter activity
J4N41_11865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4N41_11870	COG0514	ATP-dependent DNA helicase (RecQ)
J4N41_11875	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J4N41_11890	COG1477	protein flavinylation
J4N41_11895	COG2871	sodium ion transport
J4N41_11900	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J4N41_11905	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J4N41_11915	COG1805	sodium ion transport
J4N41_11920	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J4N41_11925	COG0271	Belongs to the BolA IbaG family
J4N41_11930	COG2813	Specifically methylates the guanine in position
J4N41_11960	COG1595	DNA-templated transcription, initiation
J4N41_11975	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J4N41_11980	COG0693	protein deglycase activity
J4N41_11985	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J4N41_11990	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J4N41_12000	COG0560	Phosphoserine phosphatase
J4N41_12010	COG0813	purine-nucleoside phosphorylase activity
J4N41_12015	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
J4N41_12020	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
J4N41_12035	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4N41_12040	COG0084	hydrolase, TatD family'
J4N41_12050	COG3022	response to hydroperoxide
J4N41_12055	COG1115	amino acid carrier protein
J4N41_12070	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J4N41_12080	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
J4N41_12085	COG0583	DNA-binding transcription factor activity
J4N41_12090	COG0730	response to heat
J4N41_12095	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J4N41_12100	COG0505	Belongs to the CarA family
J4N41_12110	COG0494	nUDIX hydrolase
J4N41_12115	COG0653	protein targeting
J4N41_12120	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J4N41_12125	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J4N41_12130	COG0849	cell division
J4N41_12135	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J4N41_12150	COG0772	Belongs to the SEDS family
J4N41_12155	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J4N41_12165	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J4N41_12170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J4N41_12175	COG0768	penicillin binding
J4N41_12180	COG3116	cell division
J4N41_12195	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J4N41_12200	COG3107	peptidoglycan biosynthetic process
J4N41_12205	COG0792	nuclease activity
J4N41_12210	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J4N41_12220	COG2969	positive regulation of protein catabolic process
J4N41_12225	COG0625	glutathione transferase activity
J4N41_12230	COG2857	Cytochrome c1
J4N41_12235	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J4N41_12240	COG0723	plastoquinol--plastocyanin reductase activity
J4N41_12255	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J4N41_12260	COG3105	Protein conserved in bacteria
J4N41_12265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4N41_12270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4N41_12285	COG3150	esterase
J4N41_12295	COG3151	Protein conserved in bacteria
J4N41_12300	COG0494	nUDIX hydrolase
J4N41_12305	COG1538	Outer membrane efflux protein
J4N41_12315	COG5002	protein histidine kinase activity
J4N41_12315	COG0784	Response regulator, receiver
J4N41_12315	COG2198	Histidine kinase
J4N41_12320	COG5001	Diguanylate cyclase
J4N41_12320	COG4251	negative regulation of phosphorylation
J4N41_12320	COG3706	GGDEF domain
J4N41_12320	COG2203	Gaf domain
J4N41_12325	COG1242	4 iron, 4 sulfur cluster binding
J4N41_12330	COG0070	glutamate synthase
J4N41_12330	COG0069	glutamate synthase activity
J4N41_12330	COG0067	glutamate synthase
J4N41_12340	COG0070	glutamate synthase
J4N41_12340	COG0069	glutamate synthase activity
J4N41_12340	COG0067	glutamate synthase
J4N41_12345	COG0493	'glutamate synthase
J4N41_12370	COG0195	Participates in both transcription termination and antitermination
J4N41_12375	COG0779	Required for maturation of 30S ribosomal subunits
J4N41_12450	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J4N41_12455	COG3153	acetyltransferase
J4N41_12460	COG3154	lipid carrier protein
J4N41_12470	COG0826	peptidase U32
J4N41_12475	COG0826	peptidase U32
J4N41_12480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J4N41_12500	COG0513	Belongs to the DEAD box helicase family
J4N41_12515	COG0456	acetyltransferase
J4N41_12525	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4N41_12530	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J4N41_12535	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J4N41_12540	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
J4N41_12545	COG1534	Rna-binding protein
J4N41_12550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4N41_12555	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J4N41_12570	COG0316	Belongs to the HesB IscA family
J4N41_12580	COG0628	permease
J4N41_12585	COG2813	Specifically methylates the guanine in position
J4N41_12590	COG0784	Response regulator, receiver
J4N41_12590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N41_12590	COG2198	Histidine kinase
J4N41_12590	COG2205	protein histidine kinase activity
J4N41_12595	COG0747	negative chemotaxis
J4N41_12610	COG0444	Belongs to the ABC transporter superfamily
J4N41_12615	COG4608	Belongs to the ABC transporter superfamily
J4N41_12625	COG2971	BadF BadG BcrA BcrD
J4N41_12640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4N41_12645	COG3842	ATPase activity
J4N41_12655	COG1840	ABC-type Fe3 transport system, periplasmic component
J4N41_12660	COG0004	ammonium transporteR
J4N41_12670	COG3112	Uncharacterised protein family (UPF0231)
J4N41_12675	COG1049	propionate catabolic process, 2-methylcitrate cycle
J4N41_12680	COG1752	Esterase of the alpha-beta hydrolase superfamily
J4N41_12685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4N41_12765	COG3119	arylsulfatase activity
J4N41_12770	COG1309	transcriptional regulator
J4N41_12805	COG1643	Atp-dependent helicase
J4N41_12815	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J4N41_12830	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J4N41_12835	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J4N41_12845	COG0842	Transport permease protein
J4N41_12850	COG1131	(ABC) transporter
J4N41_12855	COG0659	secondary active sulfate transmembrane transporter activity
J4N41_12860	COG0288	reversible hydration of carbon dioxide
J4N41_12875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N41_12880	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4N41_12885	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
J4N41_12890	COG2186	Transcriptional regulator
J4N41_12895	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J4N41_12900	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4N41_12905	COG4974	Belongs to the 'phage' integrase family
J4N41_12910	COG0716	FMN binding
J4N41_12920	COG0157	Belongs to the NadC ModD family
J4N41_12925	COG4969	Belongs to the N-Me-Phe pilin family
J4N41_12930	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4N41_12935	COG1459	type II secretion system
J4N41_12945	COG0237	dephospho-CoA kinase activity
J4N41_12950	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
J4N41_12955	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
J4N41_12965	COG0336	Belongs to the RNA methyltransferase TrmD family
J4N41_12975	COG0228	four-way junction DNA binding
J4N41_12980	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J4N41_12985	COG4137	Cytochrome C assembly protein
J4N41_12990	COG4536	flavin adenine dinucleotide binding
J4N41_12995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J4N41_13000	COG4942	peptidase
J4N41_13000	COG1388	LysM domain
J4N41_13010	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J4N41_13015	COG0585	pseudouridine synthase activity
J4N41_13020	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J4N41_13025	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J4N41_13030	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J4N41_13035	COG1968	undecaprenyl-diphosphatase activity
J4N41_13040	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J4N41_13045	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J4N41_13050	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J4N41_13055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J4N41_13060	COG3385	transposase activity
J4N41_13065	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J4N41_13070	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J4N41_13075	COG1610	YqeY-like protein
J4N41_13080	COG0358	DNA primase activity
J4N41_13095	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
J4N41_13100	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
J4N41_13105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4N41_13110	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J4N41_13115	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J4N41_13125	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J4N41_13130	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J4N41_13135	COG3610	response to peptide
J4N41_13140	COG2966	Psort location CytoplasmicMembrane, score
J4N41_13145	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J4N41_13155	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J4N41_13160	COG0142	geranyltranstransferase activity
J4N41_13210	COG3437	response regulator, receiver
J4N41_13225	COG0270	DNA (cytosine-5-)-methyltransferase activity
J4N41_13260	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J4N41_13325	COG1854	S-ribosylhomocysteine lyase activity
J4N41_13340	COG0612	Peptidase, M16
J4N41_13345	COG1238	metal cluster binding
J4N41_13355	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
J4N41_13360	COG0511	ligase activity, forming carbon-carbon bonds
J4N41_13360	COG5016	pyruvate
J4N41_13365	COG3630	sodium ion export across plasma membrane
J4N41_13430	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J4N41_13435	COG1546	Belongs to the CinA family
J4N41_13440	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J4N41_13445	COG0795	lipopolysaccharide-transporting ATPase activity
J4N41_13450	COG0795	lipopolysaccharide-transporting ATPase activity
J4N41_13460	COG2927	DNA polymerase III (CHI subunit)
J4N41_13465	COG0525	valine-tRNA ligase activity
J4N41_13475	COG4269	membrane
J4N41_13485	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J4N41_13490	COG0564	pseudouridine synthase activity
J4N41_13505	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J4N41_13520	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
J4N41_13525	COG0251	oxidation-reduction process
J4N41_13535	COG0039	L-malate dehydrogenase activity
J4N41_13540	COG1438	arginine binding
J4N41_13545	COG2358	TRAP transporter, solute receptor (TAXI family
J4N41_13555	COG0589	response to stress
J4N41_13580	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J4N41_13585	COG0527	aspartate kinase activity
J4N41_13590	COG0312	modulator of DNA gyrase
J4N41_13595	COG3028	Belongs to the UPF0307 family
J4N41_13600	COG0204	Acyl-transferase
J4N41_13605	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J4N41_13610	COG5007	Belongs to the BolA IbaG family
J4N41_13620	COG2854	intermembrane phospholipid transfer
J4N41_13625	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J4N41_13630	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J4N41_13635	COG1127	ABC transporter
J4N41_13645	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J4N41_13645	COG0517	IMP dehydrogenase activity
J4N41_13650	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
J4N41_13660	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J4N41_13665	COG1137	ATPase activity
J4N41_13675	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J4N41_13680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N41_13685	COG1660	Displays ATPase and GTPase activities
J4N41_13690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N41_13695	COG2239	Acts as a magnesium transporter
J4N41_13700	COG1410	methionine synthase
J4N41_13700	COG0646	methionine synthase
J4N41_13770	COG0175	sulfate reduction
J4N41_13775	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4N41_13780	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J4N41_13805	COG3437	response regulator, receiver
J4N41_13810	COG5002	protein histidine kinase activity
J4N41_13810	COG2205	protein histidine kinase activity
J4N41_13810	COG0784	Response regulator, receiver
J4N41_13815	COG0735	belongs to the Fur family
J4N41_13825	COG0529	Catalyzes the synthesis of activated sulfate
J4N41_13830	COG0471	metal ion transport
J4N41_13830	COG3273	potassium ion transport
J4N41_13845	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J4N41_13845	COG1648	precorrin-2 dehydrogenase activity
J4N41_13850	COG0737	Belongs to the 5'-nucleotidase family
J4N41_13860	COG2153	protein acetylation
J4N41_13875	COG0545	Peptidyl-prolyl cis-trans isomerase
J4N41_13885	COG0203	ribosomal protein L17
J4N41_13890	COG0202	RNA polymerase activity
J4N41_13900	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J4N41_13905	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J4N41_13910	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J4N41_13915	COG0201	protein transport
J4N41_13920	COG0200	Binds to the 23S rRNA
J4N41_13925	COG1841	ribosomal large subunit assembly
J4N41_13940	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J4N41_13945	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J4N41_13955	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J4N41_13970	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J4N41_13985	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J4N41_13990	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J4N41_13995	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J4N41_14010	COG0088	Forms part of the polypeptide exit tunnel
J4N41_14015	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J4N41_14020	COG0051	transcription antitermination factor activity, RNA binding
J4N41_14025	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4N41_14030	COG0557	exoribonuclease II activity
J4N41_14035	COG0402	S-adenosylhomocysteine deaminase activity
J4N41_14040	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
J4N41_14045	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J4N41_14055	COG1047	Peptidyl-prolyl cis-trans
J4N41_14070	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N41_14075	COG0488	(ABC) transporter
J4N41_14085	COG0429	hydrolase of the alpha beta-hydrolase fold
J4N41_14090	COG3089	Belongs to the UPF0270 family
J4N41_14095	COG3954	Phosphoribulokinase
J4N41_14100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N41_14105	COG0471	metal ion transport
J4N41_14105	COG0490	domain, Protein
J4N41_14120	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J4N41_14125	COG4942	peptidase
J4N41_14145	COG2816	NAD+ diphosphatase activity
J4N41_14150	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
J4N41_14155	COG1288	antiporter activity
J4N41_14170	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J4N41_14175	COG0540	Belongs to the ATCase OTCase family
J4N41_14180	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
J4N41_14185	COG1438	arginine binding
J4N41_14190	COG4232	protein-disulfide reductase activity
J4N41_14200	COG2095	MarC family integral membrane protein
J4N41_14210	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N41_14230	COG0149	triose-phosphate isomerase activity
J4N41_14235	COG0534	Mate efflux family protein
J4N41_14240	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J4N41_14245	COG1575	Belongs to the MenA family. Type 1 subfamily
J4N41_14250	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J4N41_14255	COG1509	lysine 2,3-aminomutase activity
J4N41_14265	COG1285	pathogenesis
J4N41_14275	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J4N41_14285	COG0745	RESPONSE REGULATOR receiver
J4N41_14290	COG2205	protein histidine kinase activity
J4N41_14295	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J4N41_14300	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J4N41_14305	COG0180	Tryptophanyl-tRNA synthetase
J4N41_14310	COG0546	phosphoglycolate phosphatase activity
J4N41_14315	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J4N41_14320	COG0338	D12 class N6 adenine-specific DNA methyltransferase
J4N41_14330	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J4N41_14365	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J4N41_14375	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J4N41_14375	COG0678	peroxiredoxin activity
J4N41_14380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N41_14385	COG0251	oxidation-reduction process
J4N41_14395	COG0165	Argininosuccinate lyase
J4N41_14395	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J4N41_14400	COG0137	argininosuccinate synthase activity
J4N41_14405	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J4N41_14410	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J4N41_14480	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J4N41_14490	COG4206	TonB-dependent receptor
J4N41_14510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N41_14515	COG0534	Mate efflux family protein
J4N41_14525	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J4N41_14530	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J4N41_14535	COG2937	Belongs to the GPAT DAPAT family
J4N41_14540	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
J4N41_14545	COG3161	chorismate lyase activity
J4N41_14550	COG1580	Controls the rotational direction of flagella during chemotaxis
J4N41_14555	COG0705	Rhomboid family
J4N41_14560	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4N41_14565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J4N41_14570	COG2177	Part of the ABC transporter FtsEX involved in
J4N41_14575	COG2884	Cell division ATP-binding protein ftsE
J4N41_14580	COG0552	protein localization to endoplasmic reticulum
J4N41_14585	COG0742	ribosomal rna small subunit methyltransferase
J4N41_14595	COG2095	MarC family integral membrane protein
J4N41_14640	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J4N41_14645	COG0640	Transcriptional regulator
J4N41_14650	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J4N41_14655	COG1280	lysine exporter protein (LysE YggA)
J4N41_14660	COG2267	carboxylic ester hydrolase activity
J4N41_14665	COG0561	phosphatase activity
J4N41_14680	COG3148	PFAM DTW domain containing protein
J4N41_14685	COG1011	Hydrolase
J4N41_14700	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J4N41_14705	COG0019	diaminopimelate decarboxylase activity
J4N41_14715	COG1965	Belongs to the frataxin family
J4N41_14720	COG3072	Adenylate cyclase
J4N41_14725	COG0181	hydroxymethylbilane synthase activity
J4N41_14730	COG1587	Uroporphyrinogen-III synthase
J4N41_14735	COG2959	enzyme of heme biosynthesis
J4N41_14740	COG3071	HemY protein
J4N41_14775	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
J4N41_14790	COG3118	belongs to the thioredoxin family
J4N41_14800	COG0248	Ppx GppA phosphatase
J4N41_14805	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J4N41_14815	COG0514	ATP-dependent DNA helicase (RecQ)
J4N41_14820	COG2962	Rard protein
J4N41_14830	COG1280	lysine exporter protein (LysE YggA)
J4N41_14835	COG0405	Gamma-glutamyltransferase
J4N41_14840	COG0210	DNA helicase
J4N41_14850	COG3220	belongs to the UPF0276 family
J4N41_14870	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J4N41_14875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N41_14890	COG0644	oxidoreductase
J4N41_14900	COG3527	Alpha-acetolactate decarboxylase
J4N41_14915	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N41_14920	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N41_14930	COG2207	Transcriptional regulator
J4N41_14935	COG3537	Alpha-1,2-mannosidase
J4N41_14945	COG3537	Alpha-1,2-mannosidase
J4N41_14950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N41_14955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N41_14955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N41_14955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N41_14975	COG0477	Major facilitator Superfamily
J4N41_14995	COG2197	response regulator
J4N41_15010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N41_15015	COG0601	transmembrane transport
J4N41_15060	COG0210	DNA helicase
J4N41_15065	COG1309	transcriptional regulator
J4N41_15070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N41_15075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N41_15080	COG2960	long-chain fatty acid transporting porin activity
J4N41_15085	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J4N41_15090	COG0583	DNA-binding transcription factor activity
J4N41_15095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J4N41_15125	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4N41_15125	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4N41_15140	COG0084	hydrolase, TatD family'
J4N41_15145	COG0805	protein transport
J4N41_15150	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J4N41_15155	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J4N41_15160	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J4N41_15170	COG2226	methyltransferase
J4N41_15175	COG1322	Protein conserved in bacteria
J4N41_15185	COG1639	'signal transduction protein
J4N41_15205	COG2081	HI0933 family
J4N41_15215	COG1528	Iron-storage protein
J4N41_15220	COG0589	response to stress
J4N41_15235	COG0742	ribosomal rna small subunit methyltransferase
J4N41_15240	COG5001	Diguanylate cyclase
J4N41_15240	COG5002	protein histidine kinase activity
J4N41_15245	COG1522	sequence-specific DNA binding
J4N41_15265	COG0006	proline dipeptidase activity
J4N41_15265	COG0006	proline dipeptidase activity
J4N41_15275	COG2022	thiamine diphosphate biosynthetic process
J4N41_15285	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J4N41_15290	COG0352	thiamine-phosphate diphosphorylase activity
J4N41_15305	COG2132	Multicopper oxidase
J4N41_15350	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4N41_15355	COG1739	Uncharacterized protein family UPF0029
J4N41_15365	COG0183	Belongs to the thiolase family
J4N41_15370	COG0583	DNA-binding transcription factor activity
J4N41_15375	COG2814	Major facilitator Superfamily
J4N41_15385	COG0765	amino acid transport
J4N41_15395	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J4N41_15400	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J4N41_15405	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J4N41_15410	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J4N41_15415	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J4N41_15420	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J4N41_15435	COG3312	ion transport
J4N41_15440	COG1475	DNA binding
J4N41_15445	COG1192	Involved in chromosome partitioning
J4N41_15450	COG0357	Ribosomal RNA small subunit methyltransferase G
J4N41_15455	COG0445	tRNA wobble uridine modification
J4N41_15460	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J4N41_15470	COG0706	membrane insertase activity
J4N41_15485	COG0230	Belongs to the bacterial ribosomal protein bL34 family
J4N41_15490	COG1126	abc transporter atp-binding protein
J4N41_15515	COG1444	tRNA N-acetyltransferase activity
J4N41_15530	COG0643	Histidine kinase
J4N41_15530	COG2198	Histidine kinase
J4N41_15540	COG0835	chemotaxis
J4N41_15545	COG0840	transmembrane signaling receptor activity
J4N41_15550	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J4N41_15600	COG0583	DNA-binding transcription factor activity
J4N41_15605	COG1175	transmembrane transport
J4N41_15625	COG0546	phosphoglycolate phosphatase activity
J4N41_15630	COG3842	ATPase activity
J4N41_15635	COG0589	response to stress
J4N41_15640	COG2723	6-phospho-beta-galactosidase activity
J4N41_15670	COG0583	DNA-binding transcription factor activity
J4N41_15685	COG0351	phosphomethylpyrimidine kinase
J4N41_15690	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J4N41_15705	COG4977	sequence-specific DNA binding
J4N41_15720	COG0671	phosphoesterase, PA-phosphatase related
J4N41_15765	COG0697	spore germination
J4N41_15810	COG2814	Major facilitator Superfamily
J4N41_15815	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J4N41_15855	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
J4N41_15870	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
J4N41_15880	COG2207	Transcriptional regulator
J4N41_15895	COG4999	Histidine kinase
J4N41_15895	COG2205	protein histidine kinase activity
J4N41_15895	COG3850	Histidine kinase
J4N41_15895	COG3437	response regulator, receiver
J4N41_15900	COG0402	S-adenosylhomocysteine deaminase activity
J4N41_15910	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J4N41_15920	COG2186	Transcriptional regulator
J4N41_15930	COG0402	S-adenosylhomocysteine deaminase activity
J4N41_15935	COG1404	Belongs to the peptidase S8 family
J4N41_15965	COG0456	acetyltransferase
J4N41_15980	COG2909	trisaccharide binding
J4N41_15985	COG0058	SHG alpha-glucan phosphorylase activity
J4N41_15990	COG1640	4-alpha-glucanotransferase
J4N41_15995	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J4N41_16015	COG1472	Belongs to the glycosyl hydrolase 3 family
J4N41_16020	COG3876	Protein conserved in bacteria
J4N41_16035	COG3293	Transposase
J4N41_16085	COG0561	phosphatase activity
J4N41_16105	COG0488	(ABC) transporter
J4N41_16130	COG1733	regulation of RNA biosynthetic process
J4N41_16135	COG0456	acetyltransferase
J4N41_16140	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J4N41_16145	COG0662	Cupin 2, conserved barrel domain protein
J4N41_16150	COG0527	aspartate kinase activity
J4N41_16170	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N41_16170	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N41_16170	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
J4N41_16175	COG0383	alpha-mannosidase activity
J4N41_16185	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N41_16185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N41_16185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N41_16210	COG0113	porphobilinogen synthase activity
J4N41_16215	COG0183	Belongs to the thiolase family
J4N41_16225	COG3246	L-lysine catabolic process to acetate
J4N41_16255	COG0583	DNA-binding transcription factor activity
J4N41_16260	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J4N41_16270	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N41_16275	COG2205	protein histidine kinase activity
J4N41_16275	COG3437	response regulator, receiver
J4N41_16275	COG3850	Histidine kinase
J4N41_16275	COG4999	Histidine kinase
J4N41_16285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J4N41_16315	COG0657	acetylesterase activity
J4N41_16325	COG3448	diguanylate cyclase activity
J4N41_16325	COG4175	Glycine betaine
J4N41_16330	COG4176	ABC-type proline glycine betaine transport system permease component
J4N41_16350	COG2095	MarC family integral membrane protein
J4N41_16360	COG0583	DNA-binding transcription factor activity
J4N41_16385	COG4964	Belongs to the GSP D family
J4N41_16395	COG2894	cell division
J4N41_16450	COG1477	protein flavinylation
J4N41_16465	COG0840	transmembrane signaling receptor activity
J4N41_16475	COG0573	inorganic phosphate transmembrane transporter activity
J4N41_16480	COG0581	inorganic phosphate transmembrane transporter activity
J4N41_16485	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4N41_16500	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
J4N41_16505	COG1162	GTPase activity
J4N41_16515	COG0363	glucosamine-6-phosphate deaminase activity
J4N41_16535	COG0454	-acetyltransferase
J4N41_16560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N41_16570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4N41_16575	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J4N41_16580	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
J4N41_16595	COG3655	Transcriptional regulator
J4N41_16605	COG0137	argininosuccinate synthase activity
J4N41_16620	COG3608	succinylglutamate desuccinylase aspartoacylase
J4N41_16640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N41_16650	COG3314	Sporulation integral membrane protein YlbJ
J4N41_16655	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4N41_16660	COG1151	hydroxylamine reductase activity
J4N41_16670	COG0583	DNA-binding transcription factor activity
J4N41_16685	COG3604	Transcriptional regulator
J4N41_16715	COG3046	protein related to deoxyribodipyrimidine photolyase
J4N41_16725	COG2329	Antibiotic biosynthesis monooxygenase
J4N41_16730	COG3304	Inner membrane component domain
J4N41_16740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N41_16795	COG0004	ammonium transporteR
J4N41_16805	COG3383	formate dehydrogenase (NAD+) activity
J4N41_16815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4N41_16835	COG0739	heme binding
J4N41_16840	COG3047	cAMP biosynthetic process
J4N41_16880	COG2271	Major facilitator Superfamily
J4N41_16885	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N41_16905	COG0431	NADPH-dependent FMN reductase
J4N41_16910	COG0697	spore germination
J4N41_16935	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J4N41_16935	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J4N41_16940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4N41_16940	COG2207	Transcriptional regulator
J4N41_16945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N41_16950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N41_16960	COG1522	sequence-specific DNA binding
J4N41_16970	COG0840	transmembrane signaling receptor activity
J4N41_16980	COG1357	PFAM Pentapeptide repeats (8 copies)
J4N41_17000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4N41_17015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N41_17025	COG1309	transcriptional regulator
J4N41_17040	COG0745	RESPONSE REGULATOR receiver
J4N41_17045	COG5002	protein histidine kinase activity
J4N41_17105	COG1054	Belongs to the UPF0176 family
J4N41_17120	COG1028	Short-chain dehydrogenase reductase Sdr
J4N41_17145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N41_17155	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J4N41_17175	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J4N41_17185	COG1733	regulation of RNA biosynthetic process
J4N41_17200	COG3795	YCII-related domain
J4N41_17205	COG4941	Belongs to the sigma-70 factor family
J4N41_17210	COG0625	glutathione transferase activity
J4N41_17215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N41_17220	COG0366	Alpha amylase catalytic
J4N41_17240	COG2084	Dehydrogenase
J4N41_17255	COG2130	NADP-dependent
J4N41_17260	COG1309	transcriptional regulator
J4N41_17275	COG3097	Belongs to the UPF0267 family
J4N41_17280	COG0513	Belongs to the DEAD box helicase family
J4N41_17290	COG1228	amidohydrolase
J4N41_17315	COG1175	transmembrane transport
J4N41_17320	COG0395	ABC-type sugar transport system, permease component
J4N41_17325	COG1554	hydrolase, family 65, central catalytic
J4N41_17330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N41_17335	COG3842	ATPase activity
J4N41_17345	COG1621	beta-fructofuranosidase activity
J4N41_17355	COG1609	Transcriptional regulator
J4N41_17380	COG3842	ATPase activity
J4N41_17385	COG1472	Belongs to the glycosyl hydrolase 3 family
J4N41_17400	COG0110	maltose O-acetyltransferase activity
J4N41_17425	COG2356	endonuclease I
J4N41_17440	COG0564	pseudouridine synthase activity
J4N41_17460	COG0583	DNA-binding transcription factor activity
J4N41_17465	COG2814	Major facilitator Superfamily
J4N41_17490	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J4N41_17500	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J4N41_17505	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J4N41_17510	COG0579	oxidoreductase
J4N41_17530	COG1012	belongs to the aldehyde dehydrogenase family
J4N41_17535	COG3284	Transcriptional regulator
J4N41_17560	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J4N41_17565	COG0363	glucosamine-6-phosphate deaminase activity
J4N41_17570	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J4N41_17575	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J4N41_17585	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J4N41_17595	COG2271	Major facilitator Superfamily
J4N41_17600	COG3851	Histidine kinase
J4N41_17605	COG2197	response regulator
J4N41_17625	COG0418	dihydroorotase activity
J4N41_17630	COG0633	Ferredoxin
J4N41_17630	COG3217	Mosc domain protein beta barrel domain protein
J4N41_17630	COG0633	Ferredoxin
J4N41_17630	COG3217	Mosc domain protein beta barrel domain protein
J4N41_17640	COG1349	DNA-binding transcription factor activity
J4N41_17660	COG2354	Protein conserved in bacteria
J4N41_17670	COG0366	Alpha amylase catalytic
J4N41_17695	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J4N41_17710	COG0739	heme binding
J4N41_17725	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
J4N41_17730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N41_17740	COG0848	biopolymer transport protein
J4N41_17745	COG0811	peptide transport
J4N41_17750	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
J4N41_17760	COG3721	Heme iron utilization protein
J4N41_17765	COG0748	coenzyme F420 binding
J4N41_17770	COG2096	Adenosyltransferase
J4N41_17775	COG3842	ATPase activity
J4N41_17785	COG1175	transmembrane transport
J4N41_17790	COG3833	ABC-type maltose transport systems, permease component
J4N41_17800	COG4533	DNA binding
J4N41_17840	COG0784	Response regulator, receiver
J4N41_17840	COG2205	protein histidine kinase activity
J4N41_17840	COG5002	protein histidine kinase activity
J4N41_17850	COG0861	Integral membrane protein TerC family
J4N41_17855	COG0402	S-adenosylhomocysteine deaminase activity
J4N41_17860	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J4N41_17865	COG1566	PFAM secretion protein HlyD family protein
J4N41_17890	COG0745	RESPONSE REGULATOR receiver
J4N41_17910	COG0121	glutamine amidotransferase
J4N41_17915	COG0531	amino acid
J4N41_17935	COG0673	inositol 2-dehydrogenase activity
J4N41_17940	COG1765	OsmC-like protein
J4N41_17945	COG3385	transposase activity
J4N41_17950	COG0110	maltose O-acetyltransferase activity
J4N41_17975	COG2304	oxidoreductase activity
J4N41_17980	COG2304	oxidoreductase activity
J4N41_17995	COG0714	Associated with various cellular activities
J4N41_18020	COG5002	protein histidine kinase activity
J4N41_18025	COG0745	RESPONSE REGULATOR receiver
J4N41_18035	COG0745	RESPONSE REGULATOR receiver
J4N41_18040	COG2205	protein histidine kinase activity
J4N41_18045	COG4452	Inner membrane protein CreD
J4N41_18050	COG0346	lactoylglutathione lyase activity
J4N41_18060	COG0156	8-amino-7-oxononanoate synthase activity
J4N41_18065	COG1063	alcohol dehydrogenase
J4N41_18080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4N41_18085	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4N41_18110	COG2205	protein histidine kinase activity
J4N41_18110	COG0784	Response regulator, receiver
J4N41_18115	COG2205	protein histidine kinase activity
J4N41_18115	COG0784	Response regulator, receiver
J4N41_18120	COG0784	Response regulator, receiver
J4N41_18120	COG2205	protein histidine kinase activity
J4N41_18120	COG5002	protein histidine kinase activity
J4N41_18135	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4N41_18140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J4N41_18145	COG3186	Phenylalanine-4-hydroxylase
J4N41_18185	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N41_18190	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N41_18215	COG1454	alcohol dehydrogenase
J4N41_18220	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
J4N41_18235	COG1011	Hydrolase
J4N41_18265	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J4N41_18270	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J4N41_18275	COG1840	ABC-type Fe3 transport system, periplasmic component
J4N41_18280	COG3842	ATPase activity
J4N41_18305	COG2866	Carboxypeptidase
J4N41_18310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4N41_18315	COG0583	DNA-binding transcription factor activity
J4N41_18320	COG1760	l-serine dehydratase
J4N41_18340	COG3706	GGDEF domain
J4N41_18345	COG0835	chemotaxis
J4N41_18345	COG0784	Response regulator, receiver
J4N41_18350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4N41_18370	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
J4N41_18375	COG0494	nUDIX hydrolase
J4N41_18380	COG0714	Associated with various cellular activities
J4N41_18385	COG2425	protein containing a von Willebrand factor type A (vWA) domain
J4N41_18405	COG3706	GGDEF domain
J4N41_18410	COG1846	Transcriptional regulator
J4N41_18415	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N41_18440	COG3048	D-serine ammonia-lyase activity
J4N41_18460	COG0814	amino acid
J4N41_18470	COG0513	Belongs to the DEAD box helicase family
J4N41_18475	COG0840	transmembrane signaling receptor activity
J4N41_18480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N41_18485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N41_18500	COG0546	phosphoglycolate phosphatase activity
J4N41_18515	COG0243	molybdopterin cofactor binding
J4N41_18520	COG1648	precorrin-2 dehydrogenase activity
J4N41_18520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J4N41_18525	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J4N41_18535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J4N41_18535	COG1116	anion transmembrane transporter activity
J4N41_18540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J4N41_18545	COG1116	anion transmembrane transporter activity
J4N41_18550	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4N41_18550	COG2146	nitrite reductase [NAD(P)H] activity
J4N41_18555	COG2146	nitrite reductase [NAD(P)H] activity
J4N41_18560	COG1858	cytochrome C peroxidase
J4N41_18585	COG3118	belongs to the thioredoxin family
J4N41_18590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J4N41_18595	COG0420	3'-5' exonuclease activity
J4N41_18600	COG0419	ATPase involved in DNA repair
J4N41_18605	COG0784	Response regulator, receiver
J4N41_18605	COG2205	protein histidine kinase activity
J4N41_18610	COG0156	8-amino-7-oxononanoate synthase activity
J4N41_18620	COG0038	chloride channel
J4N41_18625	COG0523	cobalamin synthesis protein
J4N41_18630	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J4N41_18655	COG1522	sequence-specific DNA binding
J4N41_18660	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J4N41_18665	COG1072	(Pantothenic acid kinase))
J4N41_18675	COG1063	alcohol dehydrogenase
J4N41_18680	COG2213	PTS system mannitol-specific
J4N41_18685	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N41_18690	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J4N41_18695	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J4N41_18705	COG0583	DNA-binding transcription factor activity
J4N41_18720	COG2897	thiosulfate sulfurtransferase activity
J4N41_18725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J4N41_18740	COG0513	Belongs to the DEAD box helicase family
J4N41_18745	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N41_18745	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N41_18775	COG3293	Transposase
J4N41_18780	COG0800	Aldolase
J4N41_18785	COG1803	Methylglyoxal synthase
J4N41_18790	COG1879	ABC-type sugar transport system periplasmic component
J4N41_18795	COG0784	Response regulator, receiver
J4N41_18795	COG2198	Histidine kinase
J4N41_18795	COG2205	protein histidine kinase activity
J4N41_18805	COG1979	alcohol dehydrogenase
J4N41_18810	COG2207	Transcriptional regulator
J4N41_18815	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J4N41_18825	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N41_18825	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N41_18825	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
J4N41_18830	COG1105	Belongs to the carbohydrate kinase PfkB family
J4N41_18835	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N41_18835	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N41_18840	COG1609	Transcriptional regulator
J4N41_18855	COG1492	cobalamin metabolic process
J4N41_18860	COG0725	ABC transporter, periplasmic molybdate-binding protein
J4N41_18865	COG4149	molybdate abc transporter
J4N41_18870	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
J4N41_18880	COG2203	Gaf domain
J4N41_18880	COG3706	GGDEF domain
J4N41_18880	COG5001	Diguanylate cyclase
J4N41_18880	COG4251	negative regulation of phosphorylation
J4N41_18885	COG3706	GGDEF domain
J4N41_18900	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J4N41_18905	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
J4N41_18915	COG0745	RESPONSE REGULATOR receiver
J4N41_18930	COG3140	Belongs to the UPF0181 family
J4N41_18945	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J4N41_18985	COG0023	Translation Initiation Factor
J4N41_19005	COG3266	domain, Protein
J4N41_19010	COG0045	succinate-CoA ligase (ADP-forming) activity
J4N41_19010	COG1042	CoA-binding domain protein
J4N41_19010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N41_19015	COG0583	DNA-binding transcription factor activity
J4N41_19020	COG1629	transport
J4N41_19020	COG4771	TonB-dependent receptor
J4N41_19025	COG0840	transmembrane signaling receptor activity
J4N41_19045	COG3706	GGDEF domain
J4N41_19065	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
J4N41_19070	COG1028	Short-chain dehydrogenase reductase Sdr
J4N41_19080	COG1024	Enoyl-CoA hydratase
J4N41_19085	COG1024	Enoyl-CoA hydratase
J4N41_19100	COG0183	Belongs to the thiolase family
J4N41_19110	COG1960	acyl-CoA dehydrogenase activity
J4N41_19115	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J4N41_19120	COG1024	Enoyl-CoA hydratase
J4N41_19150	COG2259	Doxx family
J4N41_19155	COG1741	Belongs to the pirin family
J4N41_19165	COG1115	amino acid carrier protein
J4N41_19170	COG0583	DNA-binding transcription factor activity
J4N41_19175	COG2910	NAD(P)H-binding
J4N41_19210	COG1132	(ABC) transporter
J4N41_19215	COG1129	ABC transporter
J4N41_19235	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J4N41_19240	COG3300	MHYT domain
J4N41_19240	COG5001	Diguanylate cyclase
J4N41_19245	COG0789	Transcriptional regulator
J4N41_19255	COG2176	DNA-directed DNA polymerase activity
J4N41_19265	COG4533	DNA binding
J4N41_19275	COG2050	protein possibly involved in aromatic compounds catabolism
J4N41_19315	COG0737	Belongs to the 5'-nucleotidase family
J4N41_19320	COG3593	DNA synthesis involved in DNA repair
J4N41_19330	COG0583	DNA-binding transcription factor activity
J4N41_19335	COG2116	formate transmembrane transporter activity
J4N41_19340	COG2353	YceI-like domain
J4N41_19345	COG3038	cytochrome b561
J4N41_19365	COG3069	C4-dicarboxylate transmembrane transporter activity
J4N41_19370	COG2197	response regulator
J4N41_19375	COG3850	Histidine kinase
J4N41_19380	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J4N41_19390	COG0243	molybdopterin cofactor binding
J4N41_19410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4N41_19415	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
J4N41_19425	COG1984	allophanate hydrolase subunit 2
J4N41_19435	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
J4N41_19440	COG4181	ATPase activity
J4N41_19450	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J4N41_19455	COG1716	ATPase activity
J4N41_19455	COG5001	Diguanylate cyclase
J4N41_19465	COG0484	heat shock protein binding
J4N41_19480	COG1324	tolerance protein
J4N41_19485	COG0210	DNA helicase
J4N41_19490	COG1289	transmembrane transporter activity
J4N41_19510	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J4N41_19535	COG2827	Endonuclease containing a URI domain
J4N41_19540	COG3132	Protein of unknown function, DUF480
J4N41_19550	COG2926	Belongs to the UPF0265 family
J4N41_19560	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J4N41_19565	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J4N41_19570	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J4N41_19580	COG0247	lactate metabolic process
J4N41_19600	COG0545	Peptidyl-prolyl cis-trans isomerase
J4N41_19610	COG0189	ligase activity
J4N41_19610	COG4067	protein conserved in archaea
J4N41_19620	COG0602	queuosine metabolic process
J4N41_19625	COG1328	CTP reductase activity
J4N41_19660	COG3240	lipase activity
J4N41_19665	COG2814	Major facilitator Superfamily
J4N41_19670	COG1794	racemase activity, acting on amino acids and derivatives
J4N41_19685	COG0183	Belongs to the thiolase family
J4N41_19695	COG1309	transcriptional regulator
J4N41_19735	COG1522	sequence-specific DNA binding
J4N41_19770	COG0515	serine threonine protein kinase
J4N41_19770	COG2815	serine threonine protein kinase
J4N41_19795	COG3501	Rhs element vgr protein
J4N41_19845	COG0739	heme binding
J4N41_19855	COG0840	transmembrane signaling receptor activity
J4N41_19880	COG2759	Belongs to the formate--tetrahydrofolate ligase family
J4N41_19910	COG4172	Belongs to the ABC transporter superfamily
J4N41_19915	COG4239	(ABC) transporter, permease
J4N41_19920	COG4174	ABC transporter (Permease)
J4N41_19925	COG4166	transmembrane transport
J4N41_19935	COG0840	transmembrane signaling receptor activity
J4N41_19940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J4N41_19945	COG1067	ATP-dependent peptidase activity
J4N41_19955	COG4172	Belongs to the ABC transporter superfamily
J4N41_19960	COG0583	DNA-binding transcription factor activity
J4N41_19965	COG1620	l-lactate permease
J4N41_19970	COG1304	FMN binding
J4N41_19985	COG3448	diguanylate cyclase activity
J4N41_19985	COG4175	Glycine betaine
J4N41_20005	COG1012	belongs to the aldehyde dehydrogenase family
J4N41_20010	COG1309	transcriptional regulator
J4N41_20020	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J4N41_20025	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J4N41_20040	COG2200	EAL domain
J4N41_20045	COG2207	Transcriptional regulator
J4N41_20050	COG2814	Major facilitator Superfamily
J4N41_20055	COG0583	DNA-binding transcription factor activity
J4N41_20060	COG3394	polysaccharide catabolic process
J4N41_20065	COG0633	Ferredoxin
J4N41_20065	COG3217	Mosc domain protein beta barrel domain protein
J4N41_20070	COG2205	protein histidine kinase activity
J4N41_20070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N41_20080	COG0657	acetylesterase activity
J4N41_20090	COG0674	pyruvate-flavodoxin oxidoreductase activity
J4N41_20090	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
J4N41_20095	COG1013	pyruvate-flavodoxin oxidoreductase activity
J4N41_20120	COG2197	response regulator
J4N41_20135	COG0516	GMP reductase activity
J4N41_20140	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J4N41_20140	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J4N41_20155	COG3437	response regulator, receiver
J4N41_20160	COG4999	Histidine kinase
J4N41_20160	COG3850	Histidine kinase
J4N41_20160	COG3437	response regulator, receiver
J4N41_20160	COG2205	protein histidine kinase activity
J4N41_20170	COG2172	sigma factor antagonist activity
J4N41_20180	COG1366	Belongs to the anti-sigma-factor antagonist family
J4N41_20185	COG0840	transmembrane signaling receptor activity
J4N41_20205	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
J4N41_20210	COG0513	Belongs to the DEAD box helicase family
J4N41_20220	COG4191	Histidine kinase
J4N41_20220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N41_20225	COG3437	response regulator, receiver
J4N41_20225	COG0784	Response regulator, receiver
J4N41_20230	COG1609	Transcriptional regulator
J4N41_20235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N41_20245	COG1172	Belongs to the binding-protein-dependent transport system permease family
J4N41_20250	COG1129	ABC transporter
J4N41_20255	COG1869	D-ribose catabolic process
J4N41_20275	COG0004	ammonium transporteR
J4N41_20300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N41_20350	COG1609	Transcriptional regulator
J4N41_20355	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J4N41_20360	COG3265	gluconokinase activity
J4N41_20365	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N41_20365	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J4N41_20375	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J4N41_20405	COG5001	Diguanylate cyclase
J4N41_20415	COG3123	guanosine phosphorylase activity
J4N41_20425	COG0668	transmembrane transport
J4N41_20445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J4N41_20485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4N41_20490	COG4232	protein-disulfide reductase activity
J4N41_20505	COG1280	lysine exporter protein (LysE YggA)
J4N41_20535	COG0443	Heat shock 70 kDa protein
J4N41_20540	COG0583	DNA-binding transcription factor activity
J4N41_20550	COG4948	Mandelate Racemase Muconate Lactonizing
J4N41_20555	COG1396	sequence-specific DNA binding
J4N41_20560	COG5001	Diguanylate cyclase
J4N41_20565	COG0683	leucine binding
J4N41_20570	COG3706	GGDEF domain
J4N41_20585	COG1523	belongs to the glycosyl hydrolase 13 family
J4N41_20605	COG3279	Response regulator of the LytR AlgR family
J4N41_20610	COG3275	phosphorelay sensor kinase activity
J4N41_20625	COG4591	ABC-type transport system involved in lipoprotein release permease component
J4N41_20630	COG1136	(ABC) transporter
J4N41_20665	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N41_20675	COG0583	DNA-binding transcription factor activity
J4N41_20685	COG3530	Putative quorum-sensing-regulated virulence factor
J4N41_20700	COG1686	Belongs to the peptidase S11 family
J4N41_20715	COG3036	rescue of stalled ribosome
J4N41_20720	COG1278	Cold shock
J4N41_20735	COG1017	nitric oxide dioxygenase activity
J4N41_20735	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4N41_20740	COG3604	Transcriptional regulator
J4N41_20755	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N41_20765	COG0534	Mate efflux family protein
J4N41_20770	COG0697	spore germination
J4N41_20790	COG0583	DNA-binding transcription factor activity
J4N41_20795	COG5001	Diguanylate cyclase
J4N41_20830	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J4N41_20840	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J4N41_20845	COG0509	glycine decarboxylation via glycine cleavage system
J4N41_20880	COG1132	(ABC) transporter
J4N41_20885	COG0589	response to stress
J4N41_20895	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J4N41_20895	COG2111	Na H antiporter
J4N41_20900	COG1006	Multisubunit Na H antiporter MnhC subunit
J4N41_20905	COG0651	ATP synthesis coupled electron transport
J4N41_20910	COG1863	multisubunit Na H antiporter MnhE subunit
J4N41_20915	COG2212	antiporter activity
J4N41_20920	COG1320	monovalent cation:proton antiporter activity
J4N41_20945	COG0673	inositol 2-dehydrogenase activity
J4N41_20960	COG5553	Cysteine dioxygenase type I
J4N41_20965	COG0840	transmembrane signaling receptor activity
J4N41_20970	COG0840	transmembrane signaling receptor activity
J4N41_21010	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
J4N41_21020	COG0438	transferase activity, transferring glycosyl groups
J4N41_21030	COG1045	serine acetyltransferase
J4N41_21045	COG0438	transferase activity, transferring glycosyl groups
J4N41_21050	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
J4N41_21055	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J4N41_21060	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J4N41_21065	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J4N41_21075	COG4989	oxidoreductase activity
J4N41_21085	COG0366	Alpha amylase catalytic
J4N41_21095	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4N41_21100	COG1126	abc transporter atp-binding protein
J4N41_21105	COG0765	amino acid transport
J4N41_21110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N41_21115	COG0765	amino acid transport
J4N41_21120	COG0109	protoheme IX farnesyltransferase activity
J4N41_21125	COG1612	heme a metabolic process
J4N41_21150	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
J4N41_21155	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J4N41_21160	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J4N41_21165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4N41_21180	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
J4N41_21185	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J4N41_21185	COG0574	Belongs to the PEP-utilizing enzyme family
J4N41_21190	COG3314	Sporulation integral membrane protein YlbJ
J4N41_21200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4N41_21225	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N41_21240	COG1741	Belongs to the pirin family
J4N41_21285	COG2205	protein histidine kinase activity
J4N41_21290	COG0745	RESPONSE REGULATOR receiver
J4N41_21315	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J4N41_21325	COG0523	cobalamin synthesis protein
J4N41_21330	COG2988	succinylglutamate desuccinylase activity
J4N41_21340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J4N41_21345	COG2423	ornithine cyclodeaminase activity
J4N41_21355	COG3938	Belongs to the proline racemase family
J4N41_21365	COG2186	Transcriptional regulator
J4N41_21380	COG0601	transmembrane transport
J4N41_21385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N41_21400	COG0006	proline dipeptidase activity
J4N41_21420	COG4934	collagen metabolic process
J4N41_21430	COG3568	Endonuclease Exonuclease Phosphatase
J4N41_21440	COG3291	Pkd domain containing protein
J4N41_21445	COG0513	Belongs to the DEAD box helicase family
J4N41_21455	COG1376	ErfK ybiS ycfS ynhG family protein
J4N41_21455	COG1388	LysM domain
J4N41_21460	COG0415	Belongs to the DNA photolyase family
J4N41_21465	COG0789	Transcriptional regulator
J4N41_21470	COG3272	Protein of unknown function (DUF1722)
J4N41_21475	COG0813	purine-nucleoside phosphorylase activity
J4N41_21505	COG1566	PFAM secretion protein HlyD family protein
J4N41_21510	COG0786	glutamate:sodium symporter activity
J4N41_21525	COG1132	(ABC) transporter
J4N41_21575	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J4N41_21585	COG0259	pyridoxamine-phosphate oxidase activity
J4N41_21615	COG3033	Beta-eliminating lyase
J4N41_21620	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
J4N41_21625	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J4N41_21630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N41_21640	COG1999	signal sequence binding
J4N41_21655	COG1671	Belongs to the UPF0178 family
J4N41_21660	COG0393	Putative heavy-metal-binding
J4N41_21665	COG0583	DNA-binding transcription factor activity
J4N41_21670	COG2814	Major facilitator Superfamily
J4N41_21680	COG0584	glycerophosphoryl diester phosphodiesterase
J4N41_21685	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J4N41_21695	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N41_21720	COG3527	Alpha-acetolactate decarboxylase
J4N41_21725	COG2814	Major facilitator Superfamily
J4N41_21730	COG0028	Belongs to the TPP enzyme family
J4N41_21890	COG1301	dicarboxylic acid transport
J4N41_21895	COG0840	transmembrane signaling receptor activity
J4N41_21910	COG4266	Belongs to the allantoicase family
J4N41_21930	COG2252	PERMEase
J4N41_21945	COG3214	Protein conserved in bacteria
J4N41_21960	COG2205	protein histidine kinase activity
J4N41_22010	COG0109	protoheme IX farnesyltransferase activity
J4N41_22015	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J4N41_22020	COG1845	cytochrome c oxidase, subunit III
J4N41_22025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J4N41_22030	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J4N41_22035	COG2706	6-phosphogluconolactonase activity
J4N41_22055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N41_22070	COG0459	protein refolding
J4N41_22075	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J4N41_22080	COG0071	Belongs to the small heat shock protein (HSP20) family
J4N41_22085	COG0628	permease
J4N41_22120	COG0668	transmembrane transport
J4N41_22125	COG1597	lipid kinase activity
J4N41_22125	COG1803	Methylglyoxal synthase
J4N41_22155	COG5002	protein histidine kinase activity
J4N41_22155	COG5001	Diguanylate cyclase
J4N41_22175	COG2084	Dehydrogenase
J4N41_22180	COG3622	Belongs to the hyi family
J4N41_22185	COG3960	tartronate-semialdehyde synthase activity
J4N41_22190	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J4N41_22200	COG0583	DNA-binding transcription factor activity
J4N41_22205	COG1288	antiporter activity
J4N41_22215	COG1846	Transcriptional regulator
J4N41_22220	COG0697	spore germination
J4N41_22225	COG1028	Short-chain dehydrogenase reductase Sdr
J4N41_22275	COG1192	Involved in chromosome partitioning
J4N41_22385	COG2200	EAL domain
J4N41_22425	COG3070	regulator of competence-specific genes
J4N41_22520	COG1309	transcriptional regulator
J4N41_22525	COG3119	arylsulfatase activity
J4N41_22910	COG1475	DNA binding
J4N41_22955	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4N41_23135	COG0433	COG0433 Predicted ATPase
J4N41_23145	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4N41_23150	COG0210	DNA helicase