locus-tag	class	description
J4N45_00010	COG0592	DNA-directed DNA polymerase activity
J4N45_00020	COG0187	DNA topoisomerase II activity
J4N45_00025	COG0071	Belongs to the small heat shock protein (HSP20) family
J4N45_00030	COG3977	Valine--pyruvate aminotransferase
J4N45_00035	COG0366	Alpha amylase catalytic
J4N45_00040	COG0751	glycine-tRNA ligase activity
J4N45_00045	COG0752	glycyl-tRNA synthetase alpha subunit
J4N45_00050	COG2119	membrane
J4N45_00060	COG0425	Belongs to the sulfur carrier protein TusA family
J4N45_00070	COG2863	cytochrome
J4N45_00075	COG3258	Cytochrome c
J4N45_00080	COG0604	alcohol dehydrogenase
J4N45_00085	COG0183	Belongs to the thiolase family
J4N45_00095	COG1739	Uncharacterized protein family UPF0029
J4N45_00100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4N45_00150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4N45_00155	COG0583	DNA-binding transcription factor activity
J4N45_00160	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J4N45_00165	COG2960	long-chain fatty acid transporting porin activity
J4N45_00170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N45_00175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N45_00180	COG1309	transcriptional regulator
J4N45_00225	COG0747	negative chemotaxis
J4N45_00230	COG0601	transmembrane transport
J4N45_00235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N45_00255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N45_00265	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J4N45_00270	COG0339	signal peptide processing
J4N45_00275	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J4N45_00280	COG1522	sequence-specific DNA binding
J4N45_00285	COG0742	ribosomal rna small subunit methyltransferase
J4N45_00300	COG0589	response to stress
J4N45_00305	COG1528	Iron-storage protein
J4N45_00315	COG2081	HI0933 family
J4N45_00320	COG0667	Aldo Keto reductase
J4N45_00330	COG2188	Transcriptional regulator
J4N45_00335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N45_00335	COG1263	PTS System
J4N45_00350	COG1388	LysM domain
J4N45_00350	COG0741	lytic transglycosylase activity
J4N45_00370	COG1815	bacterial-type flagellum-dependent cell motility
J4N45_00375	COG1558	bacterial-type flagellum-dependent cell motility
J4N45_00380	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
J4N45_00385	COG1749	Flagellar hook protein flgE
J4N45_00390	COG4787	bacterial-type flagellum-dependent cell motility
J4N45_00395	COG4786	Flagellar basal body rod
J4N45_00400	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J4N45_00405	COG1706	bacterial-type flagellum-dependent cell motility
J4N45_00415	COG1256	bacterial-type flagellum assembly
J4N45_00420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N45_00445	COG1360	Flagellar Motor Protein
J4N45_00450	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J4N45_00455	COG1191	sigma factor activity
J4N45_00460	COG1580	Controls the rotational direction of flagella during chemotaxis
J4N45_00475	COG1516	flagellar protein fliS
J4N45_00480	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J4N45_00485	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N45_00510	COG1987	bacterial-type flagellum assembly
J4N45_00570	COG1322	Protein conserved in bacteria
J4N45_00575	COG2226	methyltransferase
J4N45_00585	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J4N45_00595	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J4N45_00600	COG0805	protein transport
J4N45_00605	COG0084	hydrolase, TatD family'
J4N45_00615	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4N45_00615	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4N45_00620	COG0218	Necessary for normal cell division and for the maintenance of normal septation
J4N45_00640	COG0534	Mate efflux family protein
J4N45_00645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N45_00660	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J4N45_00665	COG4206	TonB-dependent receptor
J4N45_00675	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J4N45_00780	COG1490	D-aminoacyl-tRNA deacylase activity
J4N45_00785	COG0456	acetyltransferase
J4N45_00800	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
J4N45_00805	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J4N45_00810	COG3031	protein transport across the cell outer membrane
J4N45_00820	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4N45_00825	COG1459	type II secretion system
J4N45_00830	COG2165	general secretion pathway protein
J4N45_00835	COG2165	general secretion pathway protein
J4N45_00840	COG2165	general secretion pathway protein
J4N45_00845	COG4795	General secretion pathway protein
J4N45_00850	COG3156	type II secretion system protein K
J4N45_00855	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
J4N45_00860	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
J4N45_00870	COG1218	3'(2'),5'-bisphosphate nucleotidase
J4N45_00875	COG0494	nUDIX hydrolase
J4N45_00890	COG0596	Alpha beta hydrolase
J4N45_00900	COG2183	response to ionizing radiation
J4N45_00910	COG1253	flavin adenine dinucleotide binding
J4N45_00925	COG0151	Belongs to the GarS family
J4N45_00930	COG0138	bifunctional purine biosynthesis protein purh
J4N45_00935	COG0789	Transcriptional regulator
J4N45_00940	COG0840	transmembrane signaling receptor activity
J4N45_00945	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
J4N45_00950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4N45_00955	COG2264	protein methyltransferase activity
J4N45_00960	COG0439	Biotin carboxylase
J4N45_00965	COG0511	ligase activity, forming carbon-carbon bonds
J4N45_00970	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J4N45_00975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J4N45_00990	COG2814	Major facilitator Superfamily
J4N45_00995	COG2198	Histidine kinase
J4N45_00995	COG0784	Response regulator, receiver
J4N45_00995	COG2205	protein histidine kinase activity
J4N45_01005	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N45_01015	COG2095	MarC family integral membrane protein
J4N45_01025	COG4232	protein-disulfide reductase activity
J4N45_01030	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J4N45_01035	COG1027	Aspartate ammonia-lyase
J4N45_01040	COG3030	protein affecting phage T7 exclusion by the F plasmid
J4N45_01050	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J4N45_01055	COG1560	Kdo2-lipid A biosynthetic process
J4N45_01060	COG1560	Kdo2-lipid A biosynthetic process
J4N45_01065	COG1309	transcriptional regulator
J4N45_01070	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J4N45_01080	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J4N45_01085	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J4N45_01090	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J4N45_01095	COG2866	Carboxypeptidase
J4N45_01100	COG2205	protein histidine kinase activity
J4N45_01105	COG0745	RESPONSE REGULATOR receiver
J4N45_01115	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J4N45_01120	COG0205	6-phosphofructokinase activity
J4N45_01125	COG0149	triose-phosphate isomerase activity
J4N45_01150	COG1494	fructose-1,6-bisphosphatase
J4N45_01155	COG3074	FtsZ-dependent cytokinesis
J4N45_01170	COG4942	peptidase
J4N45_01180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4N45_01185	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
J4N45_01190	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J4N45_01195	COG1045	serine acetyltransferase
J4N45_01200	COG0534	Mate efflux family protein
J4N45_01225	COG1509	lysine 2,3-aminomutase activity
J4N45_01255	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J4N45_01260	COG1053	succinate dehydrogenase
J4N45_01265	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
J4N45_01275	COG0471	metal ion transport
J4N45_01280	COG0688	phosphatidylethanolamine metabolic process
J4N45_01285	COG1162	GTPase activity
J4N45_01360	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J4N45_01365	COG0802	atpase or kinase
J4N45_01375	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J4N45_01380	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J4N45_01390	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J4N45_01395	COG0330	HflC and HflK could
J4N45_01400	COG0330	HflC and HflK could
J4N45_01405	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
J4N45_01410	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J4N45_01415	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
J4N45_01420	COG0557	exoribonuclease II activity
J4N45_01425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4N45_01440	COG0545	Peptidyl-prolyl cis-trans isomerase
J4N45_01445	COG2964	Protein conserved in bacteria
J4N45_01450	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
J4N45_01455	COG2923	Belongs to the DsrF TusC family
J4N45_01475	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J4N45_01500	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J4N45_01505	COG0088	Forms part of the polypeptide exit tunnel
J4N45_01510	COG0089	rRNA binding
J4N45_01515	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J4N45_01520	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J4N45_01525	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J4N45_01535	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J4N45_01545	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J4N45_01555	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J4N45_01565	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J4N45_01570	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J4N45_01575	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J4N45_01590	COG1841	ribosomal large subunit assembly
J4N45_01595	COG0200	Binds to the 23S rRNA
J4N45_01600	COG0201	protein transport
J4N45_01610	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J4N45_01615	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J4N45_01625	COG0202	RNA polymerase activity
J4N45_01630	COG0203	ribosomal protein L17
J4N45_01640	COG0545	Peptidyl-prolyl cis-trans isomerase
J4N45_01650	COG2153	protein acetylation
J4N45_01660	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J4N45_01660	COG1648	precorrin-2 dehydrogenase activity
J4N45_01665	COG0175	sulfate reduction
J4N45_01670	COG2895	sulfate adenylyltransferase (ATP) activity
J4N45_01675	COG3273	potassium ion transport
J4N45_01675	COG0471	metal ion transport
J4N45_01680	COG0529	Catalyzes the synthesis of activated sulfate
J4N45_01710	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
J4N45_01720	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N45_01725	COG0729	surface antigen
J4N45_01745	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J4N45_01750	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
J4N45_01755	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J4N45_01760	COG0163	prenyltransferase activity
J4N45_01765	COG4143	(ABC) transporter
J4N45_01770	COG1178	ABC-type Fe3 transport system permease component
J4N45_01775	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
J4N45_01785	COG0312	modulator of DNA gyrase
J4N45_01795	COG0735	belongs to the Fur family
J4N45_01930	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J4N45_01940	COG0175	sulfate reduction
J4N45_01990	COG0840	transmembrane signaling receptor activity
J4N45_02030	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J4N45_02035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J4N45_02040	COG0762	integral membrane protein
J4N45_02045	COG1872	DUF167
J4N45_02055	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J4N45_02060	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J4N45_02065	COG2066	Belongs to the glutaminase family
J4N45_02070	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J4N45_02075	COG1194	a g-specific adenine glycosylase
J4N45_02080	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
J4N45_02115	COG1410	methionine synthase
J4N45_02115	COG0646	methionine synthase
J4N45_02120	COG4536	flavin adenine dinucleotide binding
J4N45_02125	COG4137	Cytochrome C assembly protein
J4N45_02130	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J4N45_02135	COG0228	four-way junction DNA binding
J4N45_02140	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J4N45_02145	COG0336	Belongs to the RNA methyltransferase TrmD family
J4N45_02150	COG0335	large ribosomal subunit rRNA binding
J4N45_02155	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
J4N45_02160	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
J4N45_02165	COG0237	dephospho-CoA kinase activity
J4N45_02175	COG1459	type II secretion system
J4N45_02180	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4N45_02200	COG2186	Transcriptional regulator
J4N45_02205	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
J4N45_02210	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4N45_02215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N45_02230	COG0288	reversible hydration of carbon dioxide
J4N45_02235	COG0659	secondary active sulfate transmembrane transporter activity
J4N45_02240	COG1131	(ABC) transporter
J4N45_02245	COG0842	Transport permease protein
J4N45_02250	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J4N45_02255	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J4N45_02255	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J4N45_02260	COG1538	Outer membrane efflux protein
J4N45_02265	COG0494	nUDIX hydrolase
J4N45_02270	COG3151	Protein conserved in bacteria
J4N45_02280	COG3150	esterase
J4N45_02295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4N45_02300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4N45_02305	COG3105	Protein conserved in bacteria
J4N45_02310	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J4N45_02320	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J4N45_02325	COG0723	plastoquinol--plastocyanin reductase activity
J4N45_02330	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J4N45_02335	COG2857	Cytochrome c1
J4N45_02340	COG0625	glutathione transferase activity
J4N45_02345	COG2969	positive regulation of protein catabolic process
J4N45_02355	COG0469	pyruvate kinase activity
J4N45_02365	COG0640	Transcriptional regulator
J4N45_02370	COG0640	Transcriptional regulator
J4N45_02375	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J4N45_02395	COG0798	PFAM Bile acid sodium symporter
J4N45_02400	COG2199	diguanylate cyclase activity
J4N45_02400	COG2203	Gaf domain
J4N45_02420	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J4N45_02425	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J4N45_02430	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J4N45_02435	COG0585	pseudouridine synthase activity
J4N45_02445	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J4N45_02450	COG1388	LysM domain
J4N45_02450	COG4942	peptidase
J4N45_02455	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J4N45_02460	COG4991	sh3 domain protein
J4N45_02465	COG0306	phosphate transporter
J4N45_02470	COG1392	Phosphate transport regulator
J4N45_02475	COG3025	triphosphatase activity
J4N45_02480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N45_02500	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J4N45_02510	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J4N45_02520	COG1489	DNA binding
J4N45_02525	COG1643	Atp-dependent helicase
J4N45_02530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4N45_02535	COG1752	Esterase of the alpha-beta hydrolase superfamily
J4N45_02540	COG1049	propionate catabolic process, 2-methylcitrate cycle
J4N45_02555	COG0628	permease
J4N45_02560	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J4N45_02565	COG0316	Belongs to the HesB IscA family
J4N45_02580	COG0028	Belongs to the TPP enzyme family
J4N45_02590	COG2823	Periplasmic or secreted lipoprotein
J4N45_02595	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J4N45_02600	COG0792	nuclease activity
J4N45_02605	COG3107	peptidoglycan biosynthetic process
J4N45_02610	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J4N45_02620	COG0275	rRNA processing
J4N45_02625	COG3116	cell division
J4N45_02630	COG0768	penicillin binding
J4N45_02640	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J4N45_02650	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J4N45_02655	COG0772	Belongs to the SEDS family
J4N45_02665	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J4N45_02670	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J4N45_02675	COG0849	cell division
J4N45_02680	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J4N45_02695	COG0494	nUDIX hydrolase
J4N45_02700	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J4N45_02705	COG0505	Belongs to the CarA family
J4N45_02710	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J4N45_02715	COG0730	response to heat
J4N45_02720	COG0583	DNA-binding transcription factor activity
J4N45_02725	COG1119	ATPase activity
J4N45_02730	COG2860	membrane
J4N45_02735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4N45_02745	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J4N45_02755	COG0493	'glutamate synthase
J4N45_02760	COG0067	glutamate synthase
J4N45_02760	COG0069	glutamate synthase activity
J4N45_02760	COG0070	glutamate synthase
J4N45_02770	COG0067	glutamate synthase
J4N45_02770	COG0069	glutamate synthase activity
J4N45_02770	COG0070	glutamate synthase
J4N45_02775	COG1242	4 iron, 4 sulfur cluster binding
J4N45_02780	COG0784	Response regulator, receiver
J4N45_02780	COG2198	Histidine kinase
J4N45_02780	COG5002	protein histidine kinase activity
J4N45_02790	COG0745	RESPONSE REGULATOR receiver
J4N45_02800	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J4N45_02815	COG0083	homoserine kinase activity
J4N45_02820	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J4N45_02830	COG1966	Carbon starvation protein
J4N45_02845	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
J4N45_02850	COG1472	Belongs to the glycosyl hydrolase 3 family
J4N45_02855	COG3279	Response regulator of the LytR AlgR family
J4N45_02860	COG3275	phosphorelay sensor kinase activity
J4N45_02865	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4N45_02870	COG1605	Chorismate mutase
J4N45_02870	COG0287	Prephenate dehydrogenase
J4N45_02895	COG0739	heme binding
J4N45_02900	COG0488	(ABC) transporter
J4N45_02910	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
J4N45_02915	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
J4N45_02925	COG1605	Chorismate mutase
J4N45_02925	COG0077	Prephenate dehydratase
J4N45_02930	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J4N45_02935	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
J4N45_02940	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N45_02945	COG0564	pseudouridine synthase activity
J4N45_02955	COG0542	response to heat
J4N45_03005	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J4N45_03010	COG0826	peptidase U32
J4N45_03015	COG2974	May be involved in recombination
J4N45_03020	COG0745	RESPONSE REGULATOR receiver
J4N45_03025	COG5002	protein histidine kinase activity
J4N45_03035	COG0248	Ppx GppA phosphatase
J4N45_03040	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J4N45_03050	COG0581	inorganic phosphate transmembrane transporter activity
J4N45_03055	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4N45_03060	COG0704	Plays a role in the regulation of phosphate uptake
J4N45_03085	COG0450	alkyl hydroperoxide reductase
J4N45_03090	COG0583	DNA-binding transcription factor activity
J4N45_03095	COG0784	Response regulator, receiver
J4N45_03095	COG2205	protein histidine kinase activity
J4N45_03105	COG2201	protein-glutamate methylesterase activity
J4N45_03110	COG3706	GGDEF domain
J4N45_03125	COG0517	IMP dehydrogenase activity
J4N45_03130	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J4N45_03135	COG0343	queuine tRNA-ribosyltransferase activity
J4N45_03140	COG1862	Preprotein translocase
J4N45_03145	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N45_03150	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N45_03155	COG0483	inositol monophosphate 1-phosphatase activity
J4N45_03160	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
J4N45_03175	COG0822	iron-sulfur transferase activity
J4N45_03180	COG0316	Belongs to the HesB IscA family
J4N45_03190	COG0443	Heat shock 70 kDa protein
J4N45_03195	COG0633	Ferredoxin
J4N45_03200	COG2975	iron-sulfur cluster assembly
J4N45_03205	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J4N45_03220	COG1426	Protein conserved in bacteria
J4N45_03225	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J4N45_03230	COG0124	histidyl-tRNA synthetase
J4N45_03235	COG2976	Protein conserved in bacteria
J4N45_03240	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N45_03245	COG1160	GTP binding
J4N45_03255	COG3300	MHYT domain
J4N45_03255	COG5001	Diguanylate cyclase
J4N45_03265	COG1570	exodeoxyribonuclease VII activity
J4N45_03270	COG0517	IMP dehydrogenase activity
J4N45_03270	COG0516	GMP reductase activity
J4N45_03275	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J4N45_03275	COG0519	Catalyzes the synthesis of GMP from XMP
J4N45_03280	COG1584	GPR1 FUN34 yaaH family protein
J4N45_03285	COG1115	amino acid carrier protein
J4N45_03290	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J4N45_03295	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J4N45_03300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J4N45_03305	COG1116	anion transmembrane transporter activity
J4N45_03320	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J4N45_03345	COG2867	negative regulation of translational initiation
J4N45_03350	COG2914	Belongs to the UPF0125 (RnfH) family
J4N45_03355	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N45_03360	COG0497	DNA recombination
J4N45_03365	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J4N45_03370	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J4N45_03375	COG1301	dicarboxylic acid transport
J4N45_03385	COG0484	heat shock protein binding
J4N45_03415	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J4N45_03420	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
J4N45_03425	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
J4N45_03430	COG0583	DNA-binding transcription factor activity
J4N45_03445	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
J4N45_03450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J4N45_03450	COG0047	phosphoribosylformylglycinamidine synthase activity
J4N45_03470	COG0442	prolyl-tRNA aminoacylation
J4N45_03475	COG1720	tRNA m6t6A37 methyltransferase activity
J4N45_03480	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J4N45_03495	COG0024	Methionine aminopeptidase
J4N45_03520	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J4N45_03525	COG0575	Belongs to the CDS family
J4N45_03535	COG0750	zinc metalloprotease
J4N45_03540	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N45_03545	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
J4N45_03550	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4N45_03555	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J4N45_03575	COG0587	DNA-directed DNA polymerase activity
J4N45_03580	COG0825	malonyl-CoA metabolic process
J4N45_03595	COG0347	Belongs to the P(II) protein family
J4N45_03600	COG3021	interspecies interaction between organisms
J4N45_03610	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J4N45_03625	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
J4N45_03630	COG1053	succinate dehydrogenase
J4N45_03640	COG0567	Dehydrogenase, E1 component
J4N45_03645	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4N45_03660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J4N45_03665	COG1121	(ABC) transporter
J4N45_03670	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
J4N45_03680	COG1984	allophanate hydrolase subunit 2
J4N45_03690	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
J4N45_03695	COG1918	ferrous iron import across plasma membrane
J4N45_03720	COG3102	Protein conserved in bacteria
J4N45_03730	COG0788	formyltetrahydrofolate deformylase activity
J4N45_03735	COG1199	ATP-dependent helicase activity
J4N45_03740	COG1214	PFAM Peptidase M22, glycoprotease
J4N45_03760	COG0318	PFAM AMP-dependent synthetase and ligase
J4N45_03765	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
J4N45_03770	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
J4N45_03775	COG2894	cell division
J4N45_03780	COG0850	regulation of cytokinetic process
J4N45_03790	COG2951	lytic endotransglycosylase activity
J4N45_03795	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N45_03800	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J4N45_03820	COG0513	Belongs to the DEAD box helicase family
J4N45_03835	COG0330	HflC and HflK could
J4N45_03840	COG3118	belongs to the thioredoxin family
J4N45_03845	COG0300	oxidoreductase activity
J4N45_03850	COG1090	epimerase
J4N45_03875	COG0622	Phosphoesterase
J4N45_03880	COG2190	(PTS) system
J4N45_03885	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J4N45_03890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N45_03895	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J4N45_03900	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J4N45_03905	COG4535	Mg2 and Co2 transporter CorC
J4N45_03915	COG1702	phosphate starvation-inducible protein PhoH
J4N45_03920	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J4N45_03925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N45_03930	COG2706	6-phosphogluconolactonase activity
J4N45_04035	COG0193	aminoacyl-tRNA hydrolase activity
J4N45_04040	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J4N45_04045	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J4N45_04050	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
J4N45_04055	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J4N45_04060	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J4N45_04065	COG2890	protein-(glutamine-N5) methyltransferase activity
J4N45_04070	COG3094	Invasion gene expression up-regulator, SirB
J4N45_04075	COG2912	Transglutaminase-like superfamily
J4N45_04080	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J4N45_04090	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J4N45_04095	COG1187	pseudouridine synthase activity
J4N45_04100	COG2840	Smr protein MutS2
J4N45_04120	COG3383	formate dehydrogenase (NAD+) activity
J4N45_04145	COG1175	transmembrane transport
J4N45_04155	COG3842	ATPase activity
J4N45_04160	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J4N45_04165	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J4N45_04170	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N45_04180	COG2204	response regulator
J4N45_04190	COG0544	peptidyl-prolyl cis-trans isomerase activity
J4N45_04200	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J4N45_04205	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J4N45_04210	COG0776	regulation of translation
J4N45_04215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4N45_04220	COG1555	photosystem II stabilization
J4N45_04235	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J4N45_04240	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
J4N45_04245	COG0436	Aminotransferase
J4N45_04250	COG1169	isochorismate synthase
J4N45_04255	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
J4N45_04260	COG0596	Alpha beta hydrolase
J4N45_04265	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
J4N45_04285	COG2855	membrane
J4N45_04290	COG2814	Major facilitator Superfamily
J4N45_04310	COG0280	phosphate acetyltransferase
J4N45_04310	COG0857	belongs to the CobB CobQ family
J4N45_04315	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J4N45_04325	COG2133	pyrroloquinoline quinone binding
J4N45_04335	COG4120	Belongs to the binding-protein-dependent transport system permease family
J4N45_04345	COG0366	Alpha amylase catalytic
J4N45_04350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4N45_04355	COG0653	protein targeting
J4N45_04375	COG2186	Transcriptional regulator
J4N45_04400	COG0572	uridine kinase
J4N45_04405	COG2982	Protein involved in outer membrane biogenesis
J4N45_04415	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
J4N45_04420	COG1438	arginine binding
J4N45_04425	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J4N45_04430	COG0549	Belongs to the carbamate kinase family
J4N45_04440	COG1288	antiporter activity
J4N45_04470	COG1178	ABC-type Fe3 transport system permease component
J4N45_04480	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J4N45_04485	COG0406	alpha-ribazole phosphatase activity
J4N45_04500	COG0395	ABC-type sugar transport system, permease component
J4N45_04510	COG0584	glycerophosphoryl diester phosphodiesterase
J4N45_04515	COG1609	Transcriptional regulator
J4N45_04520	COG0483	inositol monophosphate 1-phosphatase activity
J4N45_04540	COG0366	Alpha amylase catalytic
J4N45_04545	COG1263	PTS System
J4N45_04545	COG2190	(PTS) system
J4N45_04545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N45_04565	COG0582	viral genome integration into host DNA
J4N45_04620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J4N45_04625	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4N45_04630	COG0252	asparaginase activity
J4N45_04635	COG0616	signal peptide processing
J4N45_04640	COG0446	pyridine nucleotide-disulphide oxidoreductase
J4N45_04640	COG1902	pentaerythritol trinitrate reductase activity
J4N45_04645	COG0778	Nitroreductase
J4N45_04650	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4N45_04660	COG0123	including yeast histone deacetylase and acetoin utilization protein
J4N45_04675	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J4N45_04690	COG3083	sulfuric ester hydrolase activity
J4N45_04695	COG3082	Protein of unknown function (DUF1414)
J4N45_04700	COG3081	Nucleoid-associated protein
J4N45_04715	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J4N45_04720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N45_04725	COG2095	MarC family integral membrane protein
J4N45_04730	COG1012	belongs to the aldehyde dehydrogenase family
J4N45_04730	COG1454	alcohol dehydrogenase
J4N45_04735	COG1028	Short-chain dehydrogenase reductase Sdr
J4N45_04750	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J4N45_04755	COG3290	protein histidine kinase activity
J4N45_04755	COG0840	transmembrane signaling receptor activity
J4N45_04765	COG1522	sequence-specific DNA binding
J4N45_04770	COG1454	alcohol dehydrogenase
J4N45_04790	COG2963	transposase activity
J4N45_04795	COG1946	Acyl-CoA thioesterase
J4N45_04845	COG1061	Type III restriction enzyme res subunit
J4N45_04900	COG3706	GGDEF domain
J4N45_04905	COG2197	response regulator
J4N45_04915	COG0784	Response regulator, receiver
J4N45_04915	COG2205	protein histidine kinase activity
J4N45_04920	COG0840	transmembrane signaling receptor activity
J4N45_04930	COG3121	Chaperone
J4N45_04935	COG3188	usher protein
J4N45_05040	COG2814	Major facilitator Superfamily
J4N45_05045	COG2963	transposase activity
J4N45_05070	COG0148	phosphopyruvate hydratase activity
J4N45_05090	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N45_05100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N45_05110	COG2207	Transcriptional regulator
J4N45_05120	COG0702	epimerase
J4N45_05155	COG1566	PFAM secretion protein HlyD family protein
J4N45_05165	COG0741	lytic transglycosylase activity
J4N45_05195	COG0668	transmembrane transport
J4N45_05205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4N45_05220	COG0205	6-phosphofructokinase activity
J4N45_05265	COG0747	negative chemotaxis
J4N45_05270	COG4608	Belongs to the ABC transporter superfamily
J4N45_05275	COG0444	Belongs to the ABC transporter superfamily
J4N45_05280	COG0534	Mate efflux family protein
J4N45_05290	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J4N45_05310	COG1120	ATPase activity
J4N45_05315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N45_05320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N45_05340	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J4N45_05350	COG0523	cobalamin synthesis protein
J4N45_05355	COG2988	succinylglutamate desuccinylase activity
J4N45_05360	COG0513	Belongs to the DEAD box helicase family
J4N45_05370	COG0513	Belongs to the DEAD box helicase family
J4N45_05375	COG0534	Mate efflux family protein
J4N45_05380	COG1278	Cold shock
J4N45_05395	COG4948	Mandelate Racemase Muconate Lactonizing
J4N45_05405	COG0583	DNA-binding transcription factor activity
J4N45_05410	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J4N45_05420	COG5001	Diguanylate cyclase
J4N45_05430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4N45_05430	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
J4N45_05435	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J4N45_05440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4N45_05445	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J4N45_05455	COG0101	tRNA pseudouridine synthase activity
J4N45_05460	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J4N45_05465	COG0285	dihydrofolate synthase activity
J4N45_05470	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
J4N45_05475	COG1286	toxin biosynthetic process
J4N45_05480	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J4N45_05485	COG0583	DNA-binding transcription factor activity
J4N45_05490	COG0745	RESPONSE REGULATOR receiver
J4N45_05495	COG2832	Protein of unknown function (DUF454)
J4N45_05500	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J4N45_05515	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J4N45_05530	COG2983	Belongs to the UPF0260 family
J4N45_05620	COG2226	methyltransferase
J4N45_05625	COG0676	glucose-6-phosphate 1-epimerase activity
J4N45_05630	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J4N45_05635	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N45_05650	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J4N45_05655	COG0539	negative regulation of cytoplasmic translation
J4N45_05660	COG0776	regulation of translation
J4N45_05665	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
J4N45_05670	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
J4N45_05690	COG0583	DNA-binding transcription factor activity
J4N45_05700	COG0686	Belongs to the AlaDH PNT family
J4N45_05705	COG1522	sequence-specific DNA binding
J4N45_05710	COG1674	ftsk spoiiie
J4N45_05720	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J4N45_05730	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J4N45_05735	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J4N45_05740	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J4N45_05745	COG0156	8-amino-7-oxononanoate synthase activity
J4N45_05750	COG2226	methyltransferase
J4N45_05755	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J4N45_05760	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J4N45_05765	COG0297	glycogen (starch) synthase activity
J4N45_05785	COG3070	regulator of competence-specific genes
J4N45_05790	COG1609	Transcriptional regulator
J4N45_05800	COG0745	RESPONSE REGULATOR receiver
J4N45_05805	COG3325	Belongs to the glycosyl hydrolase 18 family
J4N45_05805	COG3469	chitinase activity
J4N45_05810	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J4N45_05815	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4N45_05820	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
J4N45_05825	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
J4N45_05830	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J4N45_05835	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
J4N45_05850	COG0730	response to heat
J4N45_05855	COG1199	ATP-dependent helicase activity
J4N45_05860	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J4N45_05900	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J4N45_05905	COG0463	Glycosyl transferase, family 2
J4N45_05910	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J4N45_05910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4N45_05915	COG0726	polysaccharide deacetylase
J4N45_05920	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
J4N45_05925	COG2076	Multidrug Resistance protein
J4N45_05930	COG2076	Multidrug Resistance protein
J4N45_05940	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J4N45_05950	COG0438	transferase activity, transferring glycosyl groups
J4N45_05965	COG0110	maltose O-acetyltransferase activity
J4N45_05980	COG2204	response regulator
J4N45_05995	COG2885	chlorophyll binding
J4N45_06005	COG0463	Glycosyl transferase, family 2
J4N45_06005	COG1216	Glycosyl transferase, family 2
J4N45_06015	COG0438	transferase activity, transferring glycosyl groups
J4N45_06020	COG1032	radical SAM domain protein
J4N45_06035	COG3012	SEC-C Motif Domain Protein
J4N45_06040	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J4N45_06045	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4N45_06050	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J4N45_06055	COG0215	cysteine-tRNA ligase activity
J4N45_06065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4N45_06070	COG0583	DNA-binding transcription factor activity
J4N45_06095	COG2116	formate transmembrane transporter activity
J4N45_06105	COG0390	transport system, permease component
J4N45_06110	COG4459	periplasmic nitrate reductase
J4N45_06115	COG3005	denitrification pathway
J4N45_06135	COG1227	inorganic diphosphatase activity
J4N45_06145	COG0671	phosphoesterase, PA-phosphatase related
J4N45_06150	COG3099	Belongs to the UPF0263 family
J4N45_06155	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J4N45_06165	COG0417	DNA replication proofreading
J4N45_06170	COG2197	response regulator
J4N45_06175	COG0322	excinuclease ABC activity
J4N45_06205	COG0307	riboflavin synthase, alpha
J4N45_06220	COG0019	diaminopimelate decarboxylase activity
J4N45_06255	COG3275	phosphorelay sensor kinase activity
J4N45_06275	COG1136	(ABC) transporter
J4N45_06275	COG0577	efflux transmembrane transporter activity
J4N45_06295	COG0625	glutathione transferase activity
J4N45_06305	COG0243	molybdopterin cofactor binding
J4N45_06310	COG0437	4 iron, 4 sulfur cluster binding
J4N45_06315	COG3302	dmso reductase anchor subunit
J4N45_06320	COG3381	protein complex oligomerization
J4N45_06330	COG0513	Belongs to the DEAD box helicase family
J4N45_06345	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J4N45_06370	COG2989	Protein conserved in bacteria
J4N45_06375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4N45_06390	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J4N45_06415	COG1846	Transcriptional regulator
J4N45_06420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N45_06445	COG1448	Aminotransferase
J4N45_06455	COG1349	DNA-binding transcription factor activity
J4N45_06470	COG0577	efflux transmembrane transporter activity
J4N45_06470	COG1136	(ABC) transporter
J4N45_06480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N45_06485	COG0017	Asparaginyl-tRNA synthetase
J4N45_06490	COG0840	transmembrane signaling receptor activity
J4N45_06500	COG0463	Glycosyl transferase, family 2
J4N45_06510	COG1760	l-serine dehydratase
J4N45_06515	COG0814	amino acid
J4N45_06520	COG0494	nUDIX hydrolase
J4N45_06545	COG3300	MHYT domain
J4N45_06545	COG5001	Diguanylate cyclase
J4N45_06560	COG0784	Response regulator, receiver
J4N45_06560	COG5002	protein histidine kinase activity
J4N45_06580	COG3106	COG3106 Predicted ATPase
J4N45_06585	COG3768	UPF0283 membrane protein
J4N45_06590	COG0471	metal ion transport
J4N45_06595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N45_06595	COG4191	Histidine kinase
J4N45_06605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4N45_06610	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J4N45_06610	COG2111	Na H antiporter
J4N45_06615	COG1006	Multisubunit Na H antiporter MnhC subunit
J4N45_06620	COG0651	ATP synthesis coupled electron transport
J4N45_06625	COG1863	multisubunit Na H antiporter MnhE subunit
J4N45_06630	COG2212	antiporter activity
J4N45_06635	COG1320	monovalent cation:proton antiporter activity
J4N45_06650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4N45_06680	COG0628	permease
J4N45_06710	COG0784	Response regulator, receiver
J4N45_06710	COG2205	protein histidine kinase activity
J4N45_06715	COG4181	ATPase activity
J4N45_06720	COG0577	efflux transmembrane transporter activity
J4N45_06745	COG1349	DNA-binding transcription factor activity
J4N45_06750	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J4N45_06755	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
J4N45_06760	COG0247	lactate metabolic process
J4N45_06775	COG4176	ABC-type proline glycine betaine transport system permease component
J4N45_06780	COG4175	Glycine betaine
J4N45_06780	COG3448	diguanylate cyclase activity
J4N45_06790	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J4N45_06795	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J4N45_06800	COG0302	gtp cyclohydrolase
J4N45_06845	COG0110	maltose O-acetyltransferase activity
J4N45_06865	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
J4N45_06870	COG1984	allophanate hydrolase subunit 2
J4N45_06885	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N45_06895	COG0154	amidase activity
J4N45_06905	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J4N45_06915	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J4N45_06950	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J4N45_06955	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J4N45_06960	COG0302	gtp cyclohydrolase
J4N45_06970	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J4N45_06990	COG1061	Type III restriction enzyme res subunit
J4N45_07000	COG2814	Major facilitator Superfamily
J4N45_07010	COG0702	epimerase
J4N45_07015	COG4181	ATPase activity
J4N45_07020	COG0577	efflux transmembrane transporter activity
J4N45_07030	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J4N45_07035	COG1309	transcriptional regulator
J4N45_07040	COG1960	acyl-CoA dehydrogenase activity
J4N45_07045	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J4N45_07050	COG2985	domain, Protein
J4N45_07050	COG3273	potassium ion transport
J4N45_07055	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J4N45_07060	COG1454	alcohol dehydrogenase
J4N45_07060	COG1012	belongs to the aldehyde dehydrogenase family
J4N45_07065	COG1737	Transcriptional regulator
J4N45_07070	COG0076	glutamate decarboxylase activity
J4N45_07080	COG2431	L-lysine efflux transmembrane transporter activity
J4N45_07090	COG3070	regulator of competence-specific genes
J4N45_07105	COG4191	Histidine kinase
J4N45_07105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N45_07115	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J4N45_07120	COG1253	flavin adenine dinucleotide binding
J4N45_07125	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J4N45_07130	COG4988	ABC transporter
J4N45_07135	COG0492	ferredoxin-NADP+ reductase activity
J4N45_07145	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J4N45_07155	COG2949	membrane
J4N45_07165	COG0281	malic enzyme
J4N45_07170	COG1643	Atp-dependent helicase
J4N45_07210	COG0277	FAD linked oxidase domain protein
J4N45_07210	COG0247	lactate metabolic process
J4N45_07215	COG2020	methyltransferase activity
J4N45_07255	COG0814	amino acid
J4N45_07260	COG0251	oxidation-reduction process
J4N45_07270	COG2375	cellular response to nickel ion
J4N45_07280	COG0366	Alpha amylase catalytic
J4N45_07305	COG4964	Belongs to the GSP D family
J4N45_07390	COG4964	Belongs to the GSP D family
J4N45_07460	COG2116	formate transmembrane transporter activity
J4N45_07470	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4N45_07480	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J4N45_07490	COG0840	transmembrane signaling receptor activity
J4N45_07495	COG3706	GGDEF domain
J4N45_07505	COG2814	Major facilitator Superfamily
J4N45_07510	COG0668	transmembrane transport
J4N45_07525	COG0534	Mate efflux family protein
J4N45_07535	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N45_07550	COG0786	glutamate:sodium symporter activity
J4N45_07555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4N45_07565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4N45_07565	COG0072	phenylalanine-tRNA ligase activity
J4N45_07580	COG0500	methyltransferase
J4N45_07585	COG3104	oligopeptide transport
J4N45_07595	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
J4N45_07600	COG4235	cytochrome complex assembly
J4N45_07605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J4N45_07615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4N45_07625	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
J4N45_07630	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
J4N45_07635	COG0437	4 iron, 4 sulfur cluster binding
J4N45_07640	COG3301	Polysulphide reductase, NrfD
J4N45_07645	COG1138	Cytochrome C-type biogenesis protein
J4N45_07650	COG3088	subunit of a heme lyase
J4N45_07650	COG4235	cytochrome complex assembly
J4N45_07670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N45_07685	COG1566	PFAM secretion protein HlyD family protein
J4N45_07725	COG0583	DNA-binding transcription factor activity
J4N45_07730	COG0583	DNA-binding transcription factor activity
J4N45_07750	COG1349	DNA-binding transcription factor activity
J4N45_07755	COG0673	inositol 2-dehydrogenase activity
J4N45_07775	COG2261	transglycosylase associated protein
J4N45_07780	COG0668	transmembrane transport
J4N45_07795	COG0454	-acetyltransferase
J4N45_07810	COG1028	Short-chain dehydrogenase reductase Sdr
J4N45_07825	COG3001	Fructosamine kinase
J4N45_07835	COG0791	NLP P60 protein
J4N45_07840	COG0840	transmembrane signaling receptor activity
J4N45_07850	COG3148	PFAM DTW domain containing protein
J4N45_07855	COG1940	carbohydrate kinase activity
J4N45_07865	COG5654	RES domain protein
J4N45_07870	COG1597	lipid kinase activity
J4N45_07875	COG0561	phosphatase activity
J4N45_07880	COG0602	queuosine metabolic process
J4N45_07895	COG2885	chlorophyll binding
J4N45_07905	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J4N45_07910	COG1254	Belongs to the acylphosphatase family
J4N45_07915	COG2920	part of a sulfur-relay system
J4N45_07920	COG0670	Belongs to the BI1 family
J4N45_07925	COG1126	abc transporter atp-binding protein
J4N45_07930	COG0765	amino acid transport
J4N45_07935	COG4597	amino acid ABC transporter
J4N45_07940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N45_07950	COG1666	GTP binding
J4N45_07955	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4N45_07965	COG1511	domain protein
J4N45_07965	COG3264	Mechanosensitive ion channel
J4N45_07985	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
J4N45_07985	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J4N45_07990	COG3008	intermembrane lipid transfer
J4N45_07995	COG2995	paraquat-inducible protein a
J4N45_08000	COG1132	(ABC) transporter
J4N45_08005	COG1956	GAF domain-containing protein
J4N45_08010	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
J4N45_08025	COG0308	aminopeptidase N
J4N45_08040	COG0167	dihydroorotate dehydrogenase activity
J4N45_08050	COG0116	Belongs to the methyltransferase superfamily
J4N45_08050	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J4N45_08060	COG0488	(ABC) transporter
J4N45_08075	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J4N45_08080	COG1067	ATP-dependent peptidase activity
J4N45_08085	COG3120	sequence-specific DNA binding
J4N45_08120	COG2205	protein histidine kinase activity
J4N45_08120	COG0784	Response regulator, receiver
J4N45_08125	COG1538	Outer membrane efflux protein
J4N45_08130	COG2274	protein secretion by the type I secretion system
J4N45_08135	COG1132	(ABC) transporter
J4N45_08145	COG3278	Belongs to the heme-copper respiratory oxidase family
J4N45_08160	COG2010	Cytochrome c
J4N45_08170	COG2217	Heavy metal translocating P-type atpase
J4N45_08185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N45_08190	COG0589	response to stress
J4N45_08195	COG2963	transposase activity
J4N45_08225	COG3842	ATPase activity
J4N45_08235	COG1177	transmembrane transport
J4N45_08240	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J4N45_08245	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J4N45_08250	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J4N45_08255	COG0004	ammonium transporteR
J4N45_08270	COG0437	4 iron, 4 sulfur cluster binding
J4N45_08275	COG3383	formate dehydrogenase (NAD+) activity
J4N45_08305	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J4N45_08315	COG3136	membrane protein required for alginate biosynthesis
J4N45_08320	COG0488	(ABC) transporter
J4N45_08355	COG3852	Histidine kinase
J4N45_08370	COG4662	Binding-protein-dependent transport system inner membrane component
J4N45_08375	COG3842	ATPase activity
J4N45_08380	COG0746	molybdenum cofactor guanylyltransferase activity
J4N45_08385	COG0303	'Molybdopterin
J4N45_08420	COG1280	lysine exporter protein (LysE YggA)
J4N45_08425	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
J4N45_08435	COG1643	Atp-dependent helicase
J4N45_08465	COG2203	Gaf domain
J4N45_08465	COG2199	diguanylate cyclase activity
J4N45_08480	COG0443	Heat shock 70 kDa protein
J4N45_08505	COG1566	PFAM secretion protein HlyD family protein
J4N45_08520	COG0384	phenazine biosynthesis protein PhzF
J4N45_08535	COG4977	sequence-specific DNA binding
J4N45_08545	COG1566	PFAM secretion protein HlyD family protein
J4N45_08560	COG2985	domain, Protein
J4N45_08570	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
J4N45_08595	COG4628	conserved protein (DUF2132)
J4N45_08600	COG1742	UPF0060 membrane protein
J4N45_08610	COG1418	mRNA catabolic process
J4N45_08625	COG5002	protein histidine kinase activity
J4N45_08625	COG0784	Response regulator, receiver
J4N45_08625	COG2205	protein histidine kinase activity
J4N45_08635	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J4N45_08635	COG0475	glutathione-regulated potassium exporter activity
J4N45_08655	COG0583	DNA-binding transcription factor activity
J4N45_08670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4N45_08685	COG2199	diguanylate cyclase activity
J4N45_08685	COG2200	EAL domain
J4N45_08695	COG2925	Exonuclease
J4N45_08705	COG1346	cytolysis
J4N45_08710	COG0295	cytidine deaminase activity
J4N45_08715	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J4N45_08730	COG1793	dna ligase
J4N45_08745	COG1115	amino acid carrier protein
J4N45_08760	COG2814	Major facilitator Superfamily
J4N45_08785	COG2828	Protein conserved in bacteria
J4N45_08790	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J4N45_08795	COG0372	Belongs to the citrate synthase family
J4N45_08800	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
J4N45_08825	COG4565	transcriptional regulatory protein
J4N45_08830	COG3290	protein histidine kinase activity
J4N45_08845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N45_08860	COG1301	dicarboxylic acid transport
J4N45_08880	COG0183	Belongs to the thiolase family
J4N45_08895	COG2207	Transcriptional regulator
J4N45_08900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N45_08905	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J4N45_08915	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J4N45_08920	COG1882	Formate acetyltransferase
J4N45_08925	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N45_08930	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N45_08935	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J4N45_08935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N45_08935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N45_08940	COG4702	Belongs to the UPF0303 family
J4N45_08945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N45_08960	COG0405	Gamma-glutamyltransferase
J4N45_08975	COG2824	Alkylphosphonate utilization operon protein PhnA
J4N45_08980	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J4N45_08980	COG0678	peroxiredoxin activity
J4N45_09015	COG0456	acetyltransferase
J4N45_09110	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J4N45_09115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N45_09140	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J4N45_09145	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J4N45_09155	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J4N45_09205	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J4N45_09210	COG1366	Belongs to the anti-sigma-factor antagonist family
J4N45_09215	COG2208	phosphoserine phosphatase activity
J4N45_09235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N45_09255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4N45_09270	COG3181	Tripartite tricarboxylate transporter family receptor
J4N45_09295	COG2186	Transcriptional regulator
J4N45_09305	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J4N45_09315	COG0402	S-adenosylhomocysteine deaminase activity
J4N45_09330	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J4N45_09340	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
J4N45_09345	COG4266	Belongs to the allantoicase family
J4N45_09365	COG2252	PERMEase
J4N45_09385	COG2084	Dehydrogenase
J4N45_09390	COG3622	Belongs to the hyi family
J4N45_09395	COG3960	tartronate-semialdehyde synthase activity
J4N45_09400	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J4N45_09410	COG1846	Transcriptional regulator
J4N45_09415	COG0697	spore germination
J4N45_09430	COG0583	DNA-binding transcription factor activity
J4N45_09455	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
J4N45_09460	COG4139	cobalamin transport
J4N45_09480	COG2815	serine threonine protein kinase
J4N45_09480	COG0515	serine threonine protein kinase
J4N45_09495	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J4N45_09500	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J4N45_09510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J4N45_09520	COG1823	symporter activity
J4N45_09530	COG0656	L-ascorbic acid biosynthetic process
J4N45_09540	COG1070	Carbohydrate kinase
J4N45_09545	COG2207	Transcriptional regulator
J4N45_09545	COG1609	Transcriptional regulator
J4N45_09800	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J4N45_10040	COG0633	Ferredoxin
J4N45_10355	COG0616	signal peptide processing
J4N45_10525	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J4N45_10715	COG2205	protein histidine kinase activity
J4N45_10720	COG0745	RESPONSE REGULATOR receiver
J4N45_10750	COG0789	Transcriptional regulator
J4N45_10760	COG0784	Response regulator, receiver
J4N45_10760	COG2205	protein histidine kinase activity
J4N45_10780	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N45_10790	COG1061	Type III restriction enzyme res subunit
J4N45_10880	COG2176	DNA-directed DNA polymerase activity
J4N45_11035	COG1988	membrane-bound metal-dependent
J4N45_11220	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J4N45_11505	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J4N45_11510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J4N45_11515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4N45_11525	COG0733	neurotransmitter:sodium symporter activity
J4N45_11540	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4N45_11545	COG2252	PERMEase
J4N45_11550	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
J4N45_11555	COG1073	alpha beta
J4N45_11570	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J4N45_11600	COG3098	single-species biofilm formation
J4N45_11605	COG0564	pseudouridine synthase activity
J4N45_11610	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J4N45_11615	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4N45_11615	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4N45_11635	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J4N45_11640	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J4N45_11645	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J4N45_11650	COG0204	Acyl-transferase
J4N45_11665	COG1024	Enoyl-CoA hydratase
J4N45_11670	COG1574	metal-dependent hydrolase with the TIM-barrel fold
J4N45_11675	COG2239	Acts as a magnesium transporter
J4N45_11710	COG1733	regulation of RNA biosynthetic process
J4N45_11720	COG1846	Transcriptional regulator
J4N45_11730	COG0586	Pfam SNARE associated Golgi protein
J4N45_11735	COG0772	Belongs to the SEDS family
J4N45_11750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4N45_11760	COG2814	Major facilitator Superfamily
J4N45_11765	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N45_11770	COG0210	DNA helicase
J4N45_11810	COG0784	Response regulator, receiver
J4N45_11810	COG0835	chemotaxis
J4N45_11815	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J4N45_11820	COG1815	bacterial-type flagellum-dependent cell motility
J4N45_11840	COG4787	bacterial-type flagellum-dependent cell motility
J4N45_11850	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J4N45_11855	COG1706	bacterial-type flagellum-dependent cell motility
J4N45_11860	COG3951	Flagellar rod assembly protein muramidase FlgJ
J4N45_11860	COG1705	Flagellar rod assembly protein muramidase FlgJ
J4N45_11875	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N45_11880	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N45_11885	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N45_11890	COG1334	flagellar protein FlaG
J4N45_11895	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J4N45_11905	COG1516	flagellar protein fliS
J4N45_11925	COG1677	Flagellar hook-basal body complex protein FliE
J4N45_11935	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J4N45_11985	COG1987	bacterial-type flagellum assembly
J4N45_12000	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J4N45_12025	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
J4N45_12030	COG0643	Histidine kinase
J4N45_12030	COG2198	Histidine kinase
J4N45_12030	COG0784	Response regulator, receiver
J4N45_12035	COG2201	protein-glutamate methylesterase activity
J4N45_12040	COG1192	Involved in chromosome partitioning
J4N45_12050	COG0835	chemotaxis
J4N45_12060	COG4133	protoheme IX ABC transporter activity
J4N45_12065	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4N45_12070	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4N45_12075	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4N45_12085	COG1138	Cytochrome C-type biogenesis protein
J4N45_12090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4N45_12095	COG3088	subunit of a heme lyase
J4N45_12095	COG4235	cytochrome complex assembly
J4N45_12105	COG2853	Lipoprotein
J4N45_12130	COG0183	Belongs to the thiolase family
J4N45_12135	COG1024	Enoyl-CoA hydratase
J4N45_12135	COG1250	3-hydroxyacyl-CoA dehydrogenase
J4N45_12140	COG1025	Belongs to the peptidase M16 family
J4N45_12145	COG2062	phosphohistidine phosphatase, SixA
J4N45_12150	COG2840	Smr protein MutS2
J4N45_12155	COG2890	protein-(glutamine-N5) methyltransferase activity
J4N45_12160	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J4N45_12165	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J4N45_12175	COG2860	membrane
J4N45_12180	COG3101	peptidyl-lysine hydroxylation
J4N45_12195	COG0673	inositol 2-dehydrogenase activity
J4N45_12215	COG0601	transmembrane transport
J4N45_12220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N45_12225	COG0444	Belongs to the ABC transporter superfamily
J4N45_12235	COG0435	Glutathione S-transferase
J4N45_12265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N45_12270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N45_12280	COG2056	Na+-H+ antiporter family
J4N45_12285	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J4N45_12315	COG0346	lactoylglutathione lyase activity
J4N45_12320	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J4N45_12325	COG4660	Part of a membrane complex involved in electron transport
J4N45_12330	COG4659	FMN binding
J4N45_12335	COG4658	electron transport chain
J4N45_12340	COG4656	Part of a membrane complex involved in electron transport
J4N45_12345	COG2878	Part of a membrane complex involved in electron transport
J4N45_12350	COG4657	Part of a membrane complex involved in electron transport
J4N45_12360	COG0556	nucleotide-excision repair
J4N45_12370	COG2198	Histidine kinase
J4N45_12375	COG0391	Required for morphogenesis under gluconeogenic growth conditions
J4N45_12380	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J4N45_12385	COG0521	Mo-molybdopterin cofactor biosynthetic process
J4N45_12390	COG0315	cyclic pyranopterin monophosphate synthase activity
J4N45_12395	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J4N45_12400	COG0314	molybdopterin synthase activity
J4N45_12410	COG0561	phosphatase activity
J4N45_12420	COG0243	molybdopterin cofactor binding
J4N45_12435	COG3707	response regulator
J4N45_12440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J4N45_12440	COG1116	anion transmembrane transporter activity
J4N45_12445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J4N45_12450	COG1116	anion transmembrane transporter activity
J4N45_12455	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4N45_12455	COG2146	nitrite reductase [NAD(P)H] activity
J4N45_12470	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J4N45_12470	COG0617	tRNA 3'-terminal CCA addition
J4N45_12470	COG0517	IMP dehydrogenase activity
J4N45_12485	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
J4N45_12490	COG0019	diaminopimelate decarboxylase activity
J4N45_12495	COG0280	phosphate acetyltransferase
J4N45_12505	COG1012	belongs to the aldehyde dehydrogenase family
J4N45_12510	COG0583	DNA-binding transcription factor activity
J4N45_12530	COG0537	adenosine 5'-monophosphoramidase activity
J4N45_12555	COG3150	esterase
J4N45_12560	COG1252	NADH dehydrogenase
J4N45_12570	COG3139	Protein of unknown function (DUF1315)
J4N45_12575	COG0659	secondary active sulfate transmembrane transporter activity
J4N45_12580	COG1530	ribonuclease E activity
J4N45_12585	COG0564	pseudouridine synthase activity
J4N45_12590	COG0424	maF-like protein
J4N45_12595	COG1399	metal-binding, possibly nucleic acid-binding protein
J4N45_12600	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J4N45_12605	COG0416	fatty acid biosynthetic process
J4N45_12610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J4N45_12635	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J4N45_12640	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J4N45_12645	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J4N45_12650	COG0470	DNA polymerase III
J4N45_12655	COG0084	hydrolase, TatD family'
J4N45_12660	COG1263	PTS System
J4N45_12660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N45_12665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N45_12675	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J4N45_12685	COG4591	ABC-type transport system involved in lipoprotein release permease component
J4N45_12690	COG1136	(ABC) transporter
J4N45_12695	COG4591	ABC-type transport system involved in lipoprotein release permease component
J4N45_12705	COG0658	competence protein
J4N45_12705	COG2333	competence protein COMEC
J4N45_12710	COG1132	(ABC) transporter
J4N45_12715	COG1663	tetraacyldisaccharide 4'-kinase activity
J4N45_12720	COG2835	tetraacyldisaccharide 4'-kinase activity
J4N45_12730	COG2963	transposase activity
J4N45_12740	COG1187	pseudouridine synthase activity
J4N45_12750	COG1278	Cold shock
J4N45_12760	COG0542	response to heat
J4N45_12765	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J4N45_12775	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J4N45_12780	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J4N45_12790	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4N45_12810	COG1028	Short-chain dehydrogenase reductase Sdr
J4N45_12825	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J4N45_12845	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J4N45_12855	COG0482	sulfurtransferase activity
J4N45_12860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N45_12865	COG2916	Histone family protein nucleoid-structuring protein H-NS
J4N45_12870	COG1757	Na H antiporter
J4N45_12885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J4N45_12890	COG0131	Imidazoleglycerol-phosphate dehydratase
J4N45_12890	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J4N45_12895	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J4N45_12900	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J4N45_12905	COG0107	imidazoleglycerol-phosphate synthase activity
J4N45_12910	COG0140	phosphoribosyl-ATP diphosphatase activity
J4N45_12910	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J4N45_12925	COG4667	esterase of the alpha-beta hydrolase superfamily
J4N45_12930	COG1940	carbohydrate kinase activity
J4N45_12935	COG0784	Response regulator, receiver
J4N45_12935	COG0835	chemotaxis
J4N45_12955	COG4667	esterase of the alpha-beta hydrolase superfamily
J4N45_12960	COG2271	Major facilitator Superfamily
J4N45_12965	COG0584	glycerophosphoryl diester phosphodiesterase
J4N45_12970	COG1028	Short-chain dehydrogenase reductase Sdr
J4N45_12975	COG0616	signal peptide processing
J4N45_12990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N45_12995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4N45_12995	COG2207	Transcriptional regulator
J4N45_13005	COG2719	SpoVR family
J4N45_13010	COG2718	Belongs to the UPF0229 family
J4N45_13015	COG2766	serine protein kinase
J4N45_13020	COG3013	Belongs to the UPF0304 family
J4N45_13025	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J4N45_13030	COG0840	transmembrane signaling receptor activity
J4N45_13040	COG1882	Formate acetyltransferase
J4N45_13070	COG4160	amino acid transport
J4N45_13090	COG0840	transmembrane signaling receptor activity
J4N45_13095	COG0189	ligase activity
J4N45_13110	COG0500	methyltransferase
J4N45_13120	COG1801	Protein of unknown function DUF72
J4N45_13130	COG0217	transcriptional regulatory protein
J4N45_13135	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J4N45_13145	COG0632	four-way junction helicase activity
J4N45_13150	COG2255	four-way junction helicase activity
J4N45_13155	COG1271	oxidase subunit
J4N45_13160	COG1294	oxidase, subunit
J4N45_13165	COG4890	Cyd operon protein YbgT
J4N45_13175	COG0824	Thioesterase
J4N45_13180	COG0811	peptide transport
J4N45_13195	COG0823	Involved in the tonB-independent uptake of proteins
J4N45_13200	COG2885	chlorophyll binding
J4N45_13205	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
J4N45_13210	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J4N45_13235	COG5002	protein histidine kinase activity
J4N45_13235	COG0784	Response regulator, receiver
J4N45_13295	COG0564	pseudouridine synthase activity
J4N45_13330	COG0556	nucleotide-excision repair
J4N45_13340	COG0419	ATPase involved in DNA repair
J4N45_13380	COG0318	PFAM AMP-dependent synthetase and ligase
J4N45_13400	COG4095	Psort location CytoplasmicMembrane, score
J4N45_13415	COG2188	Transcriptional regulator
J4N45_13425	COG0583	DNA-binding transcription factor activity
J4N45_13430	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J4N45_13440	COG2350	Protein conserved in bacteria
J4N45_13460	COG1301	dicarboxylic acid transport
J4N45_13465	COG0159	tryptophan synthase activity
J4N45_13475	COG0134	indole-3-glycerol-phosphate synthase activity
J4N45_13475	COG0135	phosphoribosylanthranilate isomerase activity
J4N45_13480	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J4N45_13485	COG0512	Glutamine amidotransferase of anthranilate synthase
J4N45_13490	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J4N45_13495	COG0613	PHP domain protein
J4N45_13500	COG0009	L-threonylcarbamoyladenylate synthase
J4N45_13505	COG1187	pseudouridine synthase activity
J4N45_13510	COG2860	membrane
J4N45_13520	COG0583	DNA-binding transcription factor activity
J4N45_13525	COG4172	Belongs to the ABC transporter superfamily
J4N45_13540	COG4168	peptide transport system, permease
J4N45_13545	COG4166	transmembrane transport
J4N45_13550	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
J4N45_13555	COG1842	Phage shock protein A
J4N45_13595	COG0519	Catalyzes the synthesis of GMP from XMP
J4N45_13640	COG0641	radical SAM
J4N45_13655	COG3119	arylsulfatase activity
J4N45_13660	COG1309	transcriptional regulator
J4N45_13685	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J4N45_13705	COG2076	Multidrug Resistance protein
J4N45_13725	COG2326	polyphosphate kinase activity
J4N45_13735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4N45_13755	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4N45_13760	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4N45_13770	COG1132	(ABC) transporter
J4N45_13775	COG1132	(ABC) transporter
J4N45_13795	COG0626	cystathionine gamma-synthase activity
J4N45_13805	COG0733	neurotransmitter:sodium symporter activity
J4N45_13810	COG0564	pseudouridine synthase activity
J4N45_13830	COG3313	Fe-S protein
J4N45_13850	COG3706	GGDEF domain
J4N45_13865	COG2233	PERMEase
J4N45_13875	COG3842	ATPase activity
J4N45_13885	COG1175	transmembrane transport
J4N45_13890	COG1653	transport
J4N45_13895	COG0584	glycerophosphoryl diester phosphodiesterase
J4N45_13900	COG1349	DNA-binding transcription factor activity
J4N45_13905	COG0784	Response regulator, receiver
J4N45_13905	COG3437	response regulator, receiver
J4N45_13910	COG1522	sequence-specific DNA binding
J4N45_13910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N45_13915	COG2313	pseudouridylate synthase activity
J4N45_13925	COG2991	Protein conserved in bacteria
J4N45_13935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N45_13940	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J4N45_13965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N45_13980	COG2963	transposase activity
J4N45_14000	COG0583	DNA-binding transcription factor activity
J4N45_14005	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N45_14010	COG1760	l-serine dehydratase
J4N45_14015	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N45_14035	COG1609	Transcriptional regulator
J4N45_14040	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J4N45_14045	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J4N45_14060	COG0656	L-ascorbic acid biosynthetic process
J4N45_14070	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J4N45_14075	COG4136	ATPase activity
J4N45_14080	COG4135	transport system, permease component
J4N45_14085	COG4134	Bacterial extracellular solute-binding protein
J4N45_14100	COG5001	Diguanylate cyclase
J4N45_14105	COG1686	Belongs to the peptidase S11 family
J4N45_14110	COG1451	nucleotide metabolic process
J4N45_14125	COG1028	Short-chain dehydrogenase reductase Sdr
J4N45_14160	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
J4N45_14175	COG0318	PFAM AMP-dependent synthetase and ligase
J4N45_14190	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
J4N45_14210	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4N45_14225	COG0584	glycerophosphoryl diester phosphodiesterase
J4N45_14235	COG3040	lipid binding
J4N45_14265	COG4580	involved in the transport of maltose and maltodextrins
J4N45_14295	COG1653	transport
J4N45_14300	COG1175	transmembrane transport
J4N45_14305	COG0395	ABC-type sugar transport system, permease component
J4N45_14310	COG3842	ATPase activity
J4N45_14320	COG4213	ABC transporter substrate-binding protein
J4N45_14325	COG1129	ABC transporter
J4N45_14330	COG4214	carbohydrate transport
J4N45_14345	COG2115	Belongs to the xylose isomerase family
J4N45_14350	COG2211	Major facilitator Superfamily
J4N45_14355	COG2207	Transcriptional regulator
J4N45_14360	COG1472	Belongs to the glycosyl hydrolase 3 family
J4N45_14370	COG1028	Short-chain dehydrogenase reductase Sdr
J4N45_14385	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J4N45_14640	COG1477	protein flavinylation
J4N45_14645	COG2871	sodium ion transport
J4N45_14650	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J4N45_14665	COG1805	sodium ion transport
J4N45_14670	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J4N45_14675	COG0271	Belongs to the BolA IbaG family
J4N45_14680	COG2813	Specifically methylates the guanine in position
J4N45_14705	COG1595	DNA-templated transcription, initiation
J4N45_14720	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J4N45_14725	COG0693	protein deglycase activity
J4N45_14730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J4N45_14735	COG2166	iron-sulfur cluster assembly
J4N45_14740	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J4N45_14745	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
J4N45_14755	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J4N45_14755	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J4N45_14765	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J4N45_14770	COG1074	ATP-dependent DNA helicase activity
J4N45_14775	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J4N45_14785	COG0583	DNA-binding transcription factor activity
J4N45_14790	COG3141	response to X-ray
J4N45_14795	COG2095	MarC family integral membrane protein
J4N45_14800	COG2171	N-acyltransferase activity
J4N45_14805	COG0250	Participates in transcription elongation, termination and antitermination
J4N45_14810	COG3104	oligopeptide transport
J4N45_14815	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J4N45_14825	COG0326	Molecular chaperone. Has ATPase activity
J4N45_14830	COG3710	Transcriptional regulator
J4N45_14845	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N45_14855	COG2837	iron assimilation
J4N45_14880	COG1393	Belongs to the ArsC family
J4N45_14890	COG1876	peptidase activity
J4N45_14900	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
J4N45_14910	COG2716	regulation of RNA biosynthetic process
J4N45_14915	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J4N45_14930	COG4783	chaperone-mediated protein folding
J4N45_14935	COG1393	Belongs to the ArsC family
J4N45_14955	COG2233	PERMEase
J4N45_14960	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J4N45_14965	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J4N45_14970	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J4N45_14975	COG0121	glutamine amidotransferase
J4N45_14980	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J4N45_14985	COG1960	acyl-CoA dehydrogenase activity
J4N45_15000	COG0328	RNA-DNA hybrid ribonuclease activity
J4N45_15005	COG2226	methyltransferase
J4N45_15010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4N45_15015	COG0741	lytic transglycosylase activity
J4N45_15015	COG1388	LysM domain
J4N45_15030	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J4N45_15035	COG1722	exodeoxyribonuclease VII activity
J4N45_15040	COG0142	geranyltranstransferase activity
J4N45_15045	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J4N45_15055	COG2608	mercury ion transmembrane transporter activity
J4N45_15055	COG2217	Heavy metal translocating P-type atpase
J4N45_15085	COG0789	Transcriptional regulator
J4N45_15115	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
J4N45_15120	COG2888	peptidyl-tyrosine sulfation
J4N45_15125	COG0495	leucyl-tRNA aminoacylation
J4N45_15130	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
J4N45_15135	COG1466	dna polymerase III delta subunit
J4N45_15140	COG0799	negative regulation of ribosome biogenesis
J4N45_15145	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J4N45_15150	COG0768	penicillin binding
J4N45_15155	COG0772	Belongs to the SEDS family
J4N45_15160	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J4N45_15165	COG1686	Belongs to the peptidase S11 family
J4N45_15170	COG2921	Belongs to the UPF0250 family
J4N45_15180	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J4N45_15190	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J4N45_15200	COG0366	Alpha amylase catalytic
J4N45_15205	COG1263	PTS System
J4N45_15205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N45_15210	COG1609	Transcriptional regulator
J4N45_15220	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J4N45_15225	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J4N45_15230	COG2011	ABC-type metal ion transport system permease component
J4N45_15235	COG1464	Belongs to the NlpA lipoprotein family
J4N45_15240	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
J4N45_15250	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J4N45_15250	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J4N45_15265	COG1611	Belongs to the LOG family
J4N45_15270	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4N45_15280	COG2363	Small membrane protein
J4N45_15290	COG0583	DNA-binding transcription factor activity
J4N45_15295	COG0033	Phosphoglucomutase
J4N45_15300	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
J4N45_15305	COG0596	Alpha beta hydrolase
J4N45_15315	COG0716	FMN binding
J4N45_15325	COG0735	belongs to the Fur family
J4N45_15335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N45_15335	COG2190	(PTS) system
J4N45_15335	COG1263	PTS System
J4N45_15340	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J4N45_15345	COG1846	Transcriptional regulator
J4N45_15345	COG1940	carbohydrate kinase activity
J4N45_15350	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J4N45_15350	COG4651	solute:proton antiporter activity
J4N45_15355	COG0367	asparagine synthase
J4N45_15365	COG0534	Mate efflux family protein
J4N45_15370	COG0583	DNA-binding transcription factor activity
J4N45_15375	COG2059	Chromate
J4N45_15395	COG0583	DNA-binding transcription factor activity
J4N45_15400	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J4N45_15405	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J4N45_15415	COG0560	Phosphoserine phosphatase
J4N45_15425	COG0813	purine-nucleoside phosphorylase activity
J4N45_15430	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
J4N45_15435	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
J4N45_15440	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
J4N45_15445	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4N45_15450	COG0084	hydrolase, TatD family'
J4N45_15460	COG1744	ABC transporter substrate-binding protein PnrA-like
J4N45_15465	COG3845	ABC transporter
J4N45_15470	COG4603	Belongs to the binding-protein-dependent transport system permease family
J4N45_15475	COG1079	Belongs to the binding-protein-dependent transport system permease family
J4N45_15480	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
J4N45_15505	COG1028	Short-chain dehydrogenase reductase Sdr
J4N45_15530	COG3154	lipid carrier protein
J4N45_15540	COG0826	peptidase U32
J4N45_15545	COG0826	peptidase U32
J4N45_15570	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J4N45_15575	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J4N45_15590	COG0195	Participates in both transcription termination and antitermination
J4N45_15610	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J4N45_15615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4N45_15620	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J4N45_15625	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J4N45_15635	COG1534	Rna-binding protein
J4N45_15640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4N45_15645	COG2027	D-alanyl-D-alanine carboxypeptidase
J4N45_15655	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J4N45_15660	COG1047	Peptidyl-prolyl cis-trans
J4N45_15665	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
J4N45_15675	COG0196	riboflavin kinase activity
J4N45_15680	COG0728	peptidoglycan biosynthetic process
J4N45_15685	COG0268	Binds directly to 16S ribosomal RNA
J4N45_15690	COG0640	Transcriptional regulator
J4N45_15695	COG0583	DNA-binding transcription factor activity
J4N45_15700	COG1283	sodium-dependent phosphate transmembrane transporter activity
J4N45_15715	COG1028	Short-chain dehydrogenase reductase Sdr
J4N45_15720	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J4N45_15725	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J4N45_15730	COG0730	response to heat
J4N45_15735	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
J4N45_15740	COG0494	nUDIX hydrolase
J4N45_15755	COG0667	Aldo Keto reductase
J4N45_15770	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J4N45_15780	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J4N45_15785	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4N45_15790	COG4974	Belongs to the 'phage' integrase family
J4N45_15795	COG0716	FMN binding
J4N45_15805	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
J4N45_15810	COG0513	Belongs to the DEAD box helicase family
J4N45_15815	COG3022	response to hydroperoxide
J4N45_15820	COG1115	amino acid carrier protein
J4N45_15835	COG0811	peptide transport
J4N45_15840	COG0811	peptide transport
J4N45_15845	COG0848	biopolymer transport protein
J4N45_15865	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J4N45_15875	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
J4N45_15880	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J4N45_15885	COG0739	heme binding
J4N45_15890	COG1022	Amp-dependent synthetase and ligase
J4N45_15895	COG0583	DNA-binding transcription factor activity
J4N45_15925	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J4N45_15930	COG0473	3-isopropylmalate dehydrogenase activity
J4N45_15940	COG0066	3-isopropylmalate dehydratase activity
J4N45_15955	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
J4N45_15960	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
J4N45_15965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4N45_15970	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J4N45_15975	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J4N45_15980	COG2967	ApaG domain
J4N45_15995	COG3610	response to peptide
J4N45_16000	COG2966	Psort location CytoplasmicMembrane, score
J4N45_16005	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J4N45_16015	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J4N45_16020	COG0142	geranyltranstransferase activity
J4N45_16035	COG1438	arginine binding
J4N45_16040	COG2358	TRAP transporter, solute receptor (TAXI family
J4N45_16050	COG0589	response to stress
J4N45_16060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J4N45_16065	COG0564	pseudouridine synthase activity
J4N45_16070	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J4N45_16075	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J4N45_16080	COG0312	modulator of DNA gyrase
J4N45_16085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J4N45_16095	COG1530	ribonuclease E activity
J4N45_16100	COG0424	maF-like protein
J4N45_16105	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
J4N45_16110	COG1792	Involved in formation and maintenance of cell shape
J4N45_16115	COG1077	Cell shape determining protein MreB Mrl
J4N45_16125	COG0457	Tetratricopeptide repeat
J4N45_16130	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
J4N45_16135	COG1215	transferase activity, transferring glycosyl groups
J4N45_16140	COG1215	transferase activity, transferring glycosyl groups
J4N45_16165	COG2194	sulfuric ester hydrolase activity
J4N45_16170	COG2199	diguanylate cyclase activity
J4N45_16170	COG2200	EAL domain
J4N45_16175	COG0629	single-stranded DNA binding
J4N45_16190	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J4N45_16205	COG3267	Type II secretory pathway component ExeA
J4N45_16205	COG3409	Peptidoglycan-binding domain 1 protein
J4N45_16210	COG0617	tRNA 3'-terminal CCA addition
J4N45_16215	COG1968	undecaprenyl-diphosphatase activity
J4N45_16220	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J4N45_16225	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J4N45_16230	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J4N45_16235	COG2267	carboxylic ester hydrolase activity
J4N45_16240	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J4N45_16245	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J4N45_16250	COG1610	YqeY-like protein
J4N45_16255	COG0358	DNA primase activity
J4N45_16275	COG3706	GGDEF domain
J4N45_16290	COG0747	negative chemotaxis
J4N45_16300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N45_16305	COG0444	Belongs to the ABC transporter superfamily
J4N45_16310	COG4608	Belongs to the ABC transporter superfamily
J4N45_16320	COG2971	BadF BadG BcrA BcrD
J4N45_16335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4N45_16340	COG3842	ATPase activity
J4N45_16350	COG1840	ABC-type Fe3 transport system, periplasmic component
J4N45_16355	COG0004	ammonium transporteR
J4N45_16370	COG3835	regulator
J4N45_16375	COG2610	gluconate transmembrane transporter activity
J4N45_16380	COG1929	Belongs to the glycerate kinase type-1 family
J4N45_16405	COG0148	phosphopyruvate hydratase activity
J4N45_16415	COG3956	TIGRFAM MazG family protein
J4N45_16420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J4N45_16425	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J4N45_16430	COG4999	Histidine kinase
J4N45_16430	COG2205	protein histidine kinase activity
J4N45_16430	COG3437	response regulator, receiver
J4N45_16430	COG3850	Histidine kinase
J4N45_16435	COG0736	holo-[acyl-carrier-protein] synthase activity
J4N45_16440	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J4N45_16445	COG1381	Involved in DNA repair and RecF pathway recombination
J4N45_16450	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J4N45_16465	COG0481	GTPase activity
J4N45_16470	COG3086	response to oxidative stress
J4N45_16485	COG1595	DNA-templated transcription, initiation
J4N45_16490	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J4N45_16495	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J4N45_16500	COG0354	folic acid binding
J4N45_16515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N45_16520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N45_16525	COG3079	Belongs to the UPF0149 family
J4N45_16530	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
J4N45_16540	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J4N45_16550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4N45_16560	COG0583	DNA-binding transcription factor activity
J4N45_16565	COG1279	arginine transmembrane transporter activity
J4N45_16575	COG0668	transmembrane transport
J4N45_16580	COG0191	fructose-bisphosphate aldolase activity
J4N45_16585	COG0126	phosphoglycerate kinase activity
J4N45_16590	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J4N45_16600	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J4N45_16605	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J4N45_16620	COG2356	endonuclease I
J4N45_16625	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J4N45_16630	COG0189	ligase activity
J4N45_16635	COG1678	Uncharacterized ACR, COG1678
J4N45_16645	COG1854	S-ribosylhomocysteine lyase activity
J4N45_16650	COG2918	glutathione biosynthetic process
J4N45_16655	COG0612	Peptidase, M16
J4N45_16660	COG1238	metal cluster binding
J4N45_16670	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
J4N45_16675	COG5016	pyruvate
J4N45_16675	COG0511	ligase activity, forming carbon-carbon bonds
J4N45_16680	COG3630	sodium ion export across plasma membrane
J4N45_16730	COG0527	aspartate kinase activity
J4N45_16740	COG2137	regulation of response to DNA damage stimulus
J4N45_16745	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J4N45_16750	COG1546	Belongs to the CinA family
J4N45_16785	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
J4N45_16790	COG0251	oxidation-reduction process
J4N45_16795	COG0204	Acyl-transferase
J4N45_16805	COG5007	Belongs to the BolA IbaG family
J4N45_16815	COG2854	intermembrane phospholipid transfer
J4N45_16820	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J4N45_16825	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J4N45_16830	COG1127	ABC transporter
J4N45_16840	COG0517	IMP dehydrogenase activity
J4N45_16840	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J4N45_16845	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
J4N45_16855	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J4N45_16860	COG1137	ATPase activity
J4N45_16870	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J4N45_16875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N45_16880	COG1660	Displays ATPase and GTPase activities
J4N45_16885	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N45_16890	COG2239	Acts as a magnesium transporter
J4N45_16895	COG0795	lipopolysaccharide-transporting ATPase activity
J4N45_16900	COG0795	lipopolysaccharide-transporting ATPase activity
J4N45_16910	COG2927	DNA polymerase III (CHI subunit)
J4N45_16915	COG0525	valine-tRNA ligase activity
J4N45_16920	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J4N45_16925	COG0527	aspartate kinase activity
J4N45_16975	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J4N45_17005	COG0432	Pfam Uncharacterised protein family UPF0047
J4N45_17010	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J4N45_17045	COG1047	Peptidyl-prolyl cis-trans
J4N45_17060	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N45_17065	COG0488	(ABC) transporter
J4N45_17075	COG1279	arginine transmembrane transporter activity
J4N45_17080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N45_17085	COG0429	hydrolase of the alpha beta-hydrolase fold
J4N45_17095	COG3954	Phosphoribulokinase
J4N45_17100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N45_17110	COG1012	belongs to the aldehyde dehydrogenase family
J4N45_17120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J4N45_17125	COG0512	Glutamine amidotransferase of anthranilate synthase
J4N45_17135	COG0180	Tryptophanyl-tRNA synthetase
J4N45_17140	COG0546	phosphoglycolate phosphatase activity
J4N45_17145	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J4N45_17150	COG0338	D12 class N6 adenine-specific DNA methyltransferase
J4N45_17160	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J4N45_17195	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J4N45_17205	COG0678	peroxiredoxin activity
J4N45_17205	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J4N45_17210	COG0251	oxidation-reduction process
J4N45_17215	COG0165	Argininosuccinate lyase
J4N45_17215	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J4N45_17235	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J4N45_17240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J4N45_17245	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
J4N45_17255	COG2963	transposase activity
J4N45_17265	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J4N45_17270	COG0527	aspartate kinase activity
J4N45_17270	COG0460	homoserine dehydrogenase
J4N45_17275	COG0626	cystathionine gamma-synthase activity
J4N45_17285	COG0281	malic enzyme
J4N45_17290	COG0254	rRNA binding
J4N45_17295	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J4N45_17300	COG1609	Transcriptional regulator
J4N45_17310	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
J4N45_17315	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
J4N45_17325	COG1575	Belongs to the MenA family. Type 1 subfamily
J4N45_17345	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J4N45_17375	COG0110	maltose O-acetyltransferase activity
J4N45_17400	COG1028	Short-chain dehydrogenase reductase Sdr
J4N45_17405	COG1083	cytidylyl-transferase
J4N45_17410	COG0673	inositol 2-dehydrogenase activity
J4N45_17425	COG2089	acid synthase
J4N45_17430	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J4N45_17435	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J4N45_17450	COG2244	polysaccharide biosynthetic process
J4N45_17485	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J4N45_17495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J4N45_17500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J4N45_17580	COG1216	Glycosyl transferase, family 2
J4N45_17625	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
J4N45_17640	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J4N45_17645	COG1596	polysaccharide export
J4N45_17650	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N45_17675	COG0726	polysaccharide deacetylase
J4N45_17680	COG0859	PFAM glycosyl transferase family 9
J4N45_17685	COG0859	PFAM glycosyl transferase family 9
J4N45_17695	COG0463	Glycosyl transferase, family 2
J4N45_17710	COG1519	Transferase
J4N45_17715	COG1216	Glycosyl transferase, family 2
J4N45_17725	COG3642	lipopolysaccharide core region biosynthetic process
J4N45_17730	COG0859	PFAM glycosyl transferase family 9
J4N45_17735	COG0463	Glycosyl transferase, family 2
J4N45_17740	COG0859	PFAM glycosyl transferase family 9
J4N45_17745	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
J4N45_17750	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
J4N45_17755	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J4N45_17760	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J4N45_17765	COG1561	YicC-like family, N-terminal region
J4N45_17770	COG2252	PERMEase
J4N45_17775	COG0194	GDP metabolic process
J4N45_17780	COG1758	RNA polymerase activity
J4N45_17785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J4N45_17790	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4N45_17795	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J4N45_17815	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4N45_17825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4N45_17845	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
J4N45_17855	COG0085	RNA polymerase activity
J4N45_17865	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J4N45_17870	COG0081	regulation of translation
J4N45_17880	COG0250	Participates in transcription elongation, termination and antitermination
J4N45_17885	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J4N45_17915	COG1072	(Pantothenic acid kinase))
J4N45_17920	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
J4N45_17920	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
J4N45_17925	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J4N45_17935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4N45_17940	COG1217	gtp-binding protein TYPA
J4N45_17945	COG0174	glutamine synthetase
J4N45_17955	COG3852	Histidine kinase
J4N45_17990	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J4N45_17995	COG2937	Belongs to the GPAT DAPAT family
J4N45_18000	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
J4N45_18010	COG1580	Controls the rotational direction of flagella during chemotaxis
J4N45_18015	COG0705	Rhomboid family
J4N45_18020	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4N45_18030	COG2177	Part of the ABC transporter FtsEX involved in
J4N45_18035	COG2884	Cell division ATP-binding protein ftsE
J4N45_18040	COG0552	protein localization to endoplasmic reticulum
J4N45_18040	COG0552	protein localization to endoplasmic reticulum
J4N45_18045	COG0742	ribosomal rna small subunit methyltransferase
J4N45_18055	COG2095	MarC family integral membrane protein
J4N45_18085	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J4N45_18090	COG1280	lysine exporter protein (LysE YggA)
J4N45_18100	COG0561	phosphatase activity
J4N45_18120	COG1011	Hydrolase
J4N45_18125	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J4N45_18135	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J4N45_18140	COG0019	diaminopimelate decarboxylase activity
J4N45_18155	COG3072	Adenylate cyclase
J4N45_18165	COG1587	Uroporphyrinogen-III synthase
J4N45_18170	COG2959	enzyme of heme biosynthesis
J4N45_18175	COG3071	HemY protein
J4N45_18225	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
J4N45_18240	COG3118	belongs to the thioredoxin family
J4N45_18250	COG0248	Ppx GppA phosphatase
J4N45_18255	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J4N45_18265	COG0514	ATP-dependent DNA helicase (RecQ)
J4N45_18270	COG2962	Rard protein
J4N45_18275	COG1280	lysine exporter protein (LysE YggA)
J4N45_18280	COG0210	DNA helicase
J4N45_18290	COG3220	belongs to the UPF0276 family
J4N45_18310	COG2814	Major facilitator Superfamily
J4N45_18315	COG0583	DNA-binding transcription factor activity
J4N45_18320	COG0006	proline dipeptidase activity
J4N45_18330	COG2022	thiamine diphosphate biosynthetic process
J4N45_18340	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J4N45_18345	COG0352	thiamine-phosphate diphosphorylase activity
J4N45_18350	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
J4N45_18400	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J4N45_18415	COG0408	coproporphyrinogen oxidase activity
J4N45_18425	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J4N45_18430	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J4N45_18435	COG0551	DNA topoisomerase type I activity
J4N45_18445	COG0758	DNA mediated transformation
J4N45_18455	COG0242	peptide deformylase activity
J4N45_18465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J4N45_18465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J4N45_18470	COG0569	domain protein
J4N45_18475	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4N45_18480	COG1272	protein, Hemolysin III
J4N45_18485	COG4326	sporulation control protein
J4N45_18495	COG3084	Protein conserved in bacteria
J4N45_18505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J4N45_18510	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4N45_18515	COG0204	Acyl-transferase
J4N45_18530	COG0606	chelatase, subunit chli
J4N45_18540	COG3978	acetolactate synthase activity
J4N45_18550	COG0129	dihydroxy-acid dehydratase activity
J4N45_18560	COG3706	GGDEF domain
J4N45_18565	COG0583	DNA-binding transcription factor activity
J4N45_18570	COG2814	Major facilitator Superfamily
J4N45_18580	COG0765	amino acid transport
J4N45_18590	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J4N45_18595	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J4N45_18600	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J4N45_18605	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J4N45_18610	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J4N45_18615	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J4N45_18630	COG3312	ion transport
J4N45_18635	COG1475	DNA binding
J4N45_18640	COG1192	Involved in chromosome partitioning
J4N45_18645	COG0357	Ribosomal RNA small subunit methyltransferase G
J4N45_18650	COG0445	tRNA wobble uridine modification
J4N45_18655	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J4N45_18660	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J4N45_18665	COG0706	membrane insertase activity
J4N45_18670	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J4N45_18680	COG0230	Belongs to the bacterial ribosomal protein bL34 family
J4N45_18685	COG1126	abc transporter atp-binding protein
J4N45_18710	COG1444	tRNA N-acetyltransferase activity
J4N45_18720	COG0789	Transcriptional regulator
J4N45_18735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N45_18760	COG0443	Heat shock 70 kDa protein
J4N45_18770	COG0583	DNA-binding transcription factor activity
J4N45_18810	COG1175	transmembrane transport
J4N45_18815	COG0395	ABC-type sugar transport system, permease component
J4N45_18820	COG1554	hydrolase, family 65, central catalytic
J4N45_18825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N45_18830	COG3842	ATPase activity
J4N45_18840	COG1621	beta-fructofuranosidase activity
J4N45_18860	COG5002	protein histidine kinase activity
J4N45_18860	COG2205	protein histidine kinase activity
J4N45_18860	COG0784	Response regulator, receiver
J4N45_18890	COG2188	Transcriptional regulator
J4N45_18895	COG3624	Phosphonate C-P lyase system protein PhnG
J4N45_18900	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
J4N45_18905	COG3626	phosphonate metabolism
J4N45_18910	COG3627	carbon phosphorus lyase activity
J4N45_18915	COG4107	phosphonate C-P lyase system protein PhnK
J4N45_18920	COG4778	phosphonate C-P lyase system protein PhnL
J4N45_18925	COG3454	Phosphonate metabolism
J4N45_18930	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
J4N45_18935	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J4N45_18965	COG0076	glutamate decarboxylase activity
J4N45_18975	COG0523	cobalamin synthesis protein
J4N45_18980	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
J4N45_18990	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J4N45_18995	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
J4N45_19015	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
J4N45_19020	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J4N45_19055	COG2113	Glycine betaine
J4N45_19080	COG4221	oxidoreductase activity
J4N45_19095	COG4948	Mandelate Racemase Muconate Lactonizing
J4N45_19100	COG1609	Transcriptional regulator
J4N45_19115	COG3568	Endonuclease Exonuclease Phosphatase
J4N45_19120	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J4N45_19135	COG0583	DNA-binding transcription factor activity
J4N45_19140	COG0702	epimerase
J4N45_19145	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N45_19155	COG0583	DNA-binding transcription factor activity
J4N45_19160	COG1024	Enoyl-CoA hydratase
J4N45_19165	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N45_19175	COG2814	Major facilitator Superfamily
J4N45_19200	COG3639	organic phosphonate transmembrane transporter activity
J4N45_19205	COG1357	PFAM Pentapeptide repeats (8 copies)
J4N45_19215	COG2909	trisaccharide binding
J4N45_19220	COG0058	SHG alpha-glucan phosphorylase activity
J4N45_19225	COG1640	4-alpha-glucanotransferase
J4N45_19230	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J4N45_19240	COG3788	relative of glutathione S-transferase, MAPEG superfamily
J4N45_19250	COG0583	DNA-binding transcription factor activity
J4N45_19255	COG1902	pentaerythritol trinitrate reductase activity
J4N45_19285	COG0778	Nitroreductase
J4N45_19290	COG4264	IucA IucC family
J4N45_19305	COG1904	glucuronate isomerase
J4N45_19310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N45_19315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N45_19330	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
J4N45_19340	COG0517	IMP dehydrogenase activity
J4N45_19340	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J4N45_19350	COG1028	Short-chain dehydrogenase reductase Sdr
J4N45_19370	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N45_19375	COG0800	Aldolase
J4N45_19385	COG1917	Cupin 2, conserved barrel domain protein
J4N45_19405	COG0628	permease
J4N45_19460	COG1280	lysine exporter protein (LysE YggA)
J4N45_19470	COG3321	synthase
J4N45_19470	COG4221	oxidoreductase activity
J4N45_19470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4N45_19470	COG0604	alcohol dehydrogenase
J4N45_19480	COG1028	Short-chain dehydrogenase reductase Sdr
J4N45_19490	COG1653	transport
J4N45_19495	COG0395	ABC-type sugar transport system, permease component
J4N45_19500	COG4209	transmembrane transport
J4N45_19505	COG3842	ATPase activity
J4N45_19520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N45_19540	COG2186	Transcriptional regulator
J4N45_19545	COG1028	Short-chain dehydrogenase reductase Sdr
J4N45_19550	COG2186	Transcriptional regulator
J4N45_19555	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J4N45_19555	COG0517	IMP dehydrogenase activity
J4N45_19560	COG2176	DNA-directed DNA polymerase activity
J4N45_19590	COG3070	regulator of competence-specific genes
J4N45_19595	COG0697	spore germination
J4N45_19605	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N45_19620	COG3706	GGDEF domain
J4N45_19630	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
J4N45_19650	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J4N45_19655	COG3706	GGDEF domain
J4N45_19660	COG1805	sodium ion transport
J4N45_19665	COG0415	Belongs to the DNA photolyase family
J4N45_19670	COG3046	protein related to deoxyribodipyrimidine photolyase
J4N45_19685	COG0384	phenazine biosynthesis protein PhzF
J4N45_19740	COG4221	oxidoreductase activity
J4N45_19755	COG4533	DNA binding
J4N45_19780	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J4N45_19790	COG1263	PTS System
J4N45_19790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N45_19800	COG1621	beta-fructofuranosidase activity
J4N45_19805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N45_19810	COG2213	PTS system mannitol-specific
J4N45_19810	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N45_19815	COG0246	Mannitol dehydrogenase
J4N45_19820	COG3722	fumarate hydratase activity
J4N45_19825	COG1349	DNA-binding transcription factor activity
J4N45_19830	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J4N45_19835	COG1609	Transcriptional regulator
J4N45_19845	COG1175	transmembrane transport
J4N45_19850	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
J4N45_19855	COG3842	ATPase activity
J4N45_19860	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
J4N45_19895	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J4N45_19910	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J4N45_19915	COG0254	rRNA binding
J4N45_19935	COG2205	protein histidine kinase activity
J4N45_19940	COG0745	RESPONSE REGULATOR receiver
J4N45_19980	COG0514	ATP-dependent DNA helicase (RecQ)
J4N45_19985	COG0363	glucosamine-6-phosphate deaminase activity
J4N45_19990	COG1764	response to oxidative stress
J4N45_19995	COG1846	Transcriptional regulator
J4N45_20000	COG0583	DNA-binding transcription factor activity
J4N45_20030	COG1454	alcohol dehydrogenase
J4N45_20055	COG3338	carbonate dehydratase activity
J4N45_20060	COG1120	ATPase activity
J4N45_20065	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
J4N45_20070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N45_20095	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
J4N45_20100	COG1757	Na H antiporter
J4N45_20105	COG0174	glutamine synthetase
J4N45_20110	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
J4N45_20115	COG1917	Cupin 2, conserved barrel domain protein
J4N45_20115	COG1396	sequence-specific DNA binding
J4N45_20120	COG1012	belongs to the aldehyde dehydrogenase family
J4N45_20125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4N45_20135	COG2957	Belongs to the agmatine deiminase family
J4N45_20140	COG1012	belongs to the aldehyde dehydrogenase family
J4N45_20145	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J4N45_20165	COG2873	o-acetylhomoserine
J4N45_20170	COG1522	sequence-specific DNA binding
J4N45_20180	COG1482	cell wall glycoprotein biosynthetic process
J4N45_20185	COG0383	alpha-mannosidase activity
J4N45_20195	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N45_20195	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N45_20195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N45_20200	COG2188	Transcriptional regulator
J4N45_20210	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J4N45_20220	COG2358	TRAP transporter, solute receptor (TAXI family
J4N45_20250	COG1234	tRNA 3'-trailer cleavage
J4N45_20310	COG3300	MHYT domain
J4N45_20310	COG5001	Diguanylate cyclase
J4N45_20350	COG0589	response to stress
J4N45_20360	COG0583	DNA-binding transcription factor activity
J4N45_20380	COG1917	Cupin 2, conserved barrel domain protein
J4N45_20380	COG2207	Transcriptional regulator
J4N45_20385	COG0625	glutathione transferase activity
J4N45_20395	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J4N45_20400	COG0612	Peptidase, M16
J4N45_20405	COG0071	Belongs to the small heat shock protein (HSP20) family
J4N45_20410	COG0443	Heat shock 70 kDa protein
J4N45_20415	COG0484	heat shock protein binding
J4N45_20425	COG0583	DNA-binding transcription factor activity
J4N45_20430	COG1566	PFAM secretion protein HlyD family protein
J4N45_20450	COG0813	purine-nucleoside phosphorylase activity
J4N45_20455	COG3272	Protein of unknown function (DUF1722)
J4N45_20460	COG0789	Transcriptional regulator
J4N45_20465	COG0415	Belongs to the DNA photolyase family
J4N45_20470	COG1388	LysM domain
J4N45_20470	COG1376	ErfK ybiS ycfS ynhG family protein
J4N45_20475	COG2963	transposase activity
J4N45_20490	COG0513	Belongs to the DEAD box helicase family
J4N45_20495	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J4N45_20500	COG0573	inorganic phosphate transmembrane transporter activity
J4N45_20505	COG0581	inorganic phosphate transmembrane transporter activity
J4N45_20510	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4N45_20520	COG3604	Transcriptional regulator
J4N45_20555	COG1011	Hydrolase
J4N45_20570	COG3278	Belongs to the heme-copper respiratory oxidase family
J4N45_20585	COG3104	oligopeptide transport
J4N45_20590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N45_20625	COG0583	DNA-binding transcription factor activity
J4N45_20645	COG4221	oxidoreductase activity
J4N45_20655	COG1819	glycosyl
J4N45_20670	COG2207	Transcriptional regulator
J4N45_20685	COG0583	DNA-binding transcription factor activity
J4N45_20695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N45_20705	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J4N45_20710	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J4N45_20715	COG1840	ABC-type Fe3 transport system, periplasmic component
J4N45_20720	COG3842	ATPase activity
J4N45_20745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N45_20750	COG3037	sugar-specific permease SgaT UlaA
J4N45_20785	COG1349	DNA-binding transcription factor activity
J4N45_20790	COG1882	Formate acetyltransferase
J4N45_20795	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J4N45_20820	COG0579	oxidoreductase
J4N45_20835	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J4N45_20860	COG0586	Pfam SNARE associated Golgi protein
J4N45_20865	COG0463	Glycosyl transferase, family 2
J4N45_20870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J4N45_20875	COG3186	Phenylalanine-4-hydroxylase
J4N45_20910	COG1454	alcohol dehydrogenase
J4N45_20915	COG1609	Transcriptional regulator
J4N45_20925	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N45_20930	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4N45_20935	COG1085	galactose-1-phosphate uridylyltransferase
J4N45_20965	COG0418	dihydroorotase activity
J4N45_20970	COG0633	Ferredoxin
J4N45_20970	COG3217	Mosc domain protein beta barrel domain protein
J4N45_20985	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J4N45_21015	COG1785	Belongs to the alkaline phosphatase family
J4N45_21020	COG1785	Belongs to the alkaline phosphatase family
J4N45_21055	COG0534	Mate efflux family protein
J4N45_21090	COG0831	urea catabolic process
J4N45_21095	COG0832	Belongs to the urease beta subunit family
J4N45_21100	COG0804	urea catabolic process
J4N45_21105	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
J4N45_21115	COG0830	nickel cation binding
J4N45_21130	COG0840	transmembrane signaling receptor activity
J4N45_21140	COG1309	transcriptional regulator
J4N45_21145	COG2130	NADP-dependent
J4N45_21195	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J4N45_21200	COG0805	protein transport
J4N45_21205	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J4N45_21220	COG0513	Belongs to the DEAD box helicase family
J4N45_21250	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J4N45_21265	COG1120	ATPase activity
J4N45_21270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N45_21275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N45_21280	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
J4N45_21285	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J4N45_21295	COG0840	transmembrane signaling receptor activity
J4N45_21320	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J4N45_21325	COG3123	guanosine phosphorylase activity
J4N45_21330	COG1741	Belongs to the pirin family
J4N45_21335	COG1940	carbohydrate kinase activity
J4N45_21340	COG1940	carbohydrate kinase activity
J4N45_21345	COG2723	6-phospho-beta-galactosidase activity
J4N45_21350	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J4N45_21365	COG3706	GGDEF domain
J4N45_21375	COG1012	belongs to the aldehyde dehydrogenase family
J4N45_21395	COG1139	Iron-sulfur cluster binding protein
J4N45_21400	COG0247	lactate metabolic process
J4N45_21405	COG1620	l-lactate permease
J4N45_21410	COG0583	DNA-binding transcription factor activity
J4N45_21435	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
J4N45_21440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N45_21455	COG3721	Heme iron utilization protein
J4N45_21460	COG0748	coenzyme F420 binding
J4N45_21470	COG0583	DNA-binding transcription factor activity
J4N45_21475	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4N45_21475	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J4N45_21480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4N45_21485	COG4232	protein-disulfide reductase activity
J4N45_21530	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N45_21535	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N45_21540	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J4N45_21550	COG3005	denitrification pathway
J4N45_21560	COG0243	molybdopterin cofactor binding
J4N45_21570	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J4N45_21570	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
J4N45_21575	COG3850	Histidine kinase
J4N45_21580	COG2197	response regulator
J4N45_21595	COG0733	neurotransmitter:sodium symporter activity
J4N45_21605	COG0745	RESPONSE REGULATOR receiver
J4N45_21610	COG2205	protein histidine kinase activity
J4N45_21625	COG1609	Transcriptional regulator
J4N45_21630	COG3842	ATPase activity
J4N45_21635	COG1175	transmembrane transport
J4N45_21640	COG0395	ABC-type sugar transport system, permease component
J4N45_21650	COG3250	beta-galactosidase activity
J4N45_21655	COG1085	galactose-1-phosphate uridylyltransferase
J4N45_21660	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
J4N45_21665	COG2017	converts alpha-aldose to the beta-anomer
J4N45_21670	COG2199	diguanylate cyclase activity
J4N45_21670	COG2203	Gaf domain
J4N45_21695	COG5001	Diguanylate cyclase
J4N45_21695	COG3300	MHYT domain
J4N45_21710	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J4N45_21715	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J4N45_21725	COG0583	DNA-binding transcription factor activity
J4N45_21735	COG2897	thiosulfate sulfurtransferase activity
J4N45_21745	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J4N45_21755	COG0302	gtp cyclohydrolase
J4N45_21775	COG0038	chloride channel
J4N45_21780	COG0523	cobalamin synthesis protein
J4N45_21790	COG0714	Associated with various cellular activities
J4N45_21810	COG2304	oxidoreductase activity
J4N45_21825	COG0673	inositol 2-dehydrogenase activity
J4N45_21830	COG0456	acetyltransferase
J4N45_21835	COG1253	flavin adenine dinucleotide binding
J4N45_21840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4N45_21845	COG0174	glutamine synthetase
J4N45_21850	COG0174	glutamine synthetase
J4N45_21860	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J4N45_21865	COG3842	ATPase activity
J4N45_21870	COG1176	ABC-type spermidine putrescine transport system, permease component I
J4N45_21875	COG1177	transmembrane transport
J4N45_21895	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4N45_21895	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4N45_21920	COG2354	Protein conserved in bacteria
J4N45_21935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N45_21940	COG1538	Outer membrane efflux protein
J4N45_21955	COG0366	Alpha amylase catalytic
J4N45_21980	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4N45_22000	COG0745	RESPONSE REGULATOR receiver
J4N45_22005	COG2205	protein histidine kinase activity
J4N45_22010	COG0420	3'-5' exonuclease activity
J4N45_22015	COG0419	ATPase involved in DNA repair
J4N45_22020	COG3097	Belongs to the UPF0267 family
J4N45_22025	COG1683	Conserved Protein
J4N45_22040	COG2885	chlorophyll binding
J4N45_22040	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
J4N45_22055	COG1858	cytochrome C peroxidase
J4N45_22075	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J4N45_22075	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J4N45_22080	COG0516	GMP reductase activity
J4N45_22105	COG3706	GGDEF domain
J4N45_22120	COG1028	Short-chain dehydrogenase reductase Sdr
J4N45_22145	COG1566	PFAM secretion protein HlyD family protein
J4N45_22155	COG0300	oxidoreductase activity
J4N45_22160	COG2197	response regulator
J4N45_22165	COG3119	arylsulfatase activity
J4N45_22175	COG0641	radical SAM
J4N45_22190	COG0714	Associated with various cellular activities
J4N45_22210	COG2304	oxidoreductase activity
J4N45_22235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N45_22255	COG0625	glutathione transferase activity
J4N45_22295	COG4989	oxidoreductase activity
J4N45_22300	COG0739	heme binding
J4N45_22305	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J4N45_22320	COG3119	arylsulfatase activity
J4N45_22325	COG3119	arylsulfatase activity
J4N45_22330	COG0210	DNA helicase
J4N45_22335	COG0840	transmembrane signaling receptor activity
J4N45_22340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N45_22345	COG0545	Peptidyl-prolyl cis-trans isomerase
J4N45_22355	COG2885	chlorophyll binding
J4N45_22360	COG2759	Belongs to the formate--tetrahydrofolate ligase family
J4N45_22365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N45_22370	COG2199	diguanylate cyclase activity
J4N45_22385	COG0546	phosphoglycolate phosphatase activity
J4N45_22400	COG0814	amino acid
J4N45_22410	COG2824	Alkylphosphonate utilization operon protein PhnA
J4N45_22415	COG2267	carboxylic ester hydrolase activity
J4N45_22420	COG2067	long-chain fatty acid transport protein
J4N45_22425	COG0501	Belongs to the peptidase M48B family
J4N45_22430	COG2050	protein possibly involved in aromatic compounds catabolism
J4N45_22440	COG4533	DNA binding
J4N45_22465	COG2801	Transposase and inactivated derivatives
J4N45_22465	COG3415	Transposase
J4N45_22470	COG0668	transmembrane transport
J4N45_22475	COG0569	domain protein
J4N45_22480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4N45_22485	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N45_22485	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N45_22490	COG1765	OsmC-like protein
J4N45_22505	COG2267	carboxylic ester hydrolase activity
J4N45_22510	COG0534	Mate efflux family protein
J4N45_22520	COG3118	belongs to the thioredoxin family
J4N45_22525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J4N45_22610	COG3038	cytochrome b561
J4N45_22615	COG2353	YceI-like domain
J4N45_22625	COG2116	formate transmembrane transporter activity
J4N45_22630	COG0583	DNA-binding transcription factor activity
J4N45_22640	COG3593	DNA synthesis involved in DNA repair
J4N45_22645	COG0737	Belongs to the 5'-nucleotidase family
J4N45_22655	COG5507	3-demethylubiquinone-9 3-methyltransferase
J4N45_22675	COG3132	Protein of unknown function, DUF480
J4N45_22685	COG1879	ABC-type sugar transport system periplasmic component
J4N45_22705	COG1289	transmembrane transporter activity
J4N45_22720	COG0583	DNA-binding transcription factor activity
J4N45_22725	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
J4N45_22730	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
J4N45_22735	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J4N45_22770	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J4N45_22805	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N45_22825	COG1328	CTP reductase activity
J4N45_22830	COG0602	queuosine metabolic process
J4N45_22840	COG0189	ligase activity
J4N45_22840	COG4067	protein conserved in archaea
J4N45_22855	COG0725	ABC transporter, periplasmic molybdate-binding protein
J4N45_22860	COG4149	molybdate abc transporter
J4N45_22865	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
J4N45_22875	COG3706	GGDEF domain
J4N45_22885	COG3706	GGDEF domain
J4N45_22900	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J4N45_22905	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
J4N45_22935	COG0023	Translation Initiation Factor
J4N45_22945	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J4N45_22950	COG1181	Belongs to the D-alanine--D-alanine ligase family
J4N45_22960	COG0045	succinate-CoA ligase (ADP-forming) activity
J4N45_22960	COG1042	CoA-binding domain protein
J4N45_22960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N45_22965	COG0583	DNA-binding transcription factor activity
J4N45_22980	COG2963	transposase activity
J4N45_23010	COG2205	protein histidine kinase activity
J4N45_23010	COG2198	Histidine kinase
J4N45_23010	COG0784	Response regulator, receiver
J4N45_23015	COG1879	ABC-type sugar transport system periplasmic component
J4N45_23020	COG1803	Methylglyoxal synthase
J4N45_23035	COG4067	protein conserved in archaea
J4N45_23035	COG0189	ligase activity
J4N45_23045	COG0189	ligase activity
J4N45_23055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N45_23065	COG4181	ATPase activity
J4N45_23075	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J4N45_23080	COG3300	MHYT domain
J4N45_23080	COG5001	Diguanylate cyclase
J4N45_23090	COG0484	heat shock protein binding
J4N45_23100	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4N45_23105	COG0612	Peptidase, M16
J4N45_23170	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N45_23180	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J4N45_23185	COG0515	serine threonine protein kinase
J4N45_23290	COG2814	Major facilitator Superfamily
J4N45_23300	COG0784	Response regulator, receiver
J4N45_23300	COG3437	response regulator, receiver
J4N45_23305	COG4191	Histidine kinase
J4N45_23305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N45_23420	COG2814	Major facilitator Superfamily
J4N45_23430	COG1063	alcohol dehydrogenase
J4N45_23445	COG0346	lactoylglutathione lyase activity
J4N45_23465	COG1874	Beta-galactosidase
J4N45_23465	COG0366	Alpha amylase catalytic
J4N45_23530	COG1028	Short-chain dehydrogenase reductase Sdr
J4N45_23540	COG1024	Enoyl-CoA hydratase
J4N45_23545	COG1024	Enoyl-CoA hydratase
J4N45_23550	COG1960	acyl-CoA dehydrogenase activity
J4N45_23560	COG0183	Belongs to the thiolase family
J4N45_23570	COG1960	acyl-CoA dehydrogenase activity
J4N45_23575	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J4N45_23580	COG1024	Enoyl-CoA hydratase
J4N45_23600	COG2199	diguanylate cyclase activity
J4N45_23605	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J4N45_23610	COG0513	Belongs to the DEAD box helicase family
J4N45_23615	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
J4N45_23625	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J4N45_23630	COG0393	Putative heavy-metal-binding
J4N45_23660	COG0415	Belongs to the DNA photolyase family
J4N45_23675	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4N45_23680	COG2425	protein containing a von Willebrand factor type A (vWA) domain
J4N45_23690	COG2425	protein containing a von Willebrand factor type A (vWA) domain
J4N45_23700	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
J4N45_23710	COG0531	amino acid
J4N45_23725	COG1320	monovalent cation:proton antiporter activity
J4N45_23730	COG2212	antiporter activity
J4N45_23735	COG1863	multisubunit Na H antiporter MnhE subunit
J4N45_23740	COG0651	ATP synthesis coupled electron transport
J4N45_23745	COG1006	Multisubunit Na H antiporter MnhC subunit
J4N45_23750	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J4N45_23750	COG2111	Na H antiporter
J4N45_23760	COG0589	response to stress
J4N45_23765	COG0513	Belongs to the DEAD box helicase family
J4N45_23770	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
J4N45_23785	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4N45_23800	COG0826	peptidase U32
J4N45_23815	COG0312	modulator of DNA gyrase
J4N45_23820	COG0312	modulator of DNA gyrase
J4N45_23840	COG2814	Major facilitator Superfamily
J4N45_23845	COG1609	Transcriptional regulator
J4N45_23850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N45_23855	COG1879	ABC-type sugar transport system periplasmic component
J4N45_23860	COG1172	Belongs to the binding-protein-dependent transport system permease family
J4N45_23865	COG1129	ABC transporter
J4N45_23870	COG1869	D-ribose catabolic process
J4N45_23880	COG0110	maltose O-acetyltransferase activity
J4N45_23890	COG0625	glutathione transferase activity
J4N45_23900	COG0786	glutamate:sodium symporter activity
J4N45_23910	COG0641	radical SAM
J4N45_23925	COG0583	DNA-binding transcription factor activity
J4N45_23945	COG0519	Catalyzes the synthesis of GMP from XMP
J4N45_23955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J4N45_23965	COG1012	belongs to the aldehyde dehydrogenase family
J4N45_23970	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
J4N45_24005	COG3530	Putative quorum-sensing-regulated virulence factor
J4N45_24020	COG3070	regulator of competence-specific genes
J4N45_24040	COG1355	regulation of microtubule-based process
J4N45_24050	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
J4N45_24055	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J4N45_24065	COG1979	alcohol dehydrogenase
J4N45_24075	COG0149	triose-phosphate isomerase activity
J4N45_24085	COG2376	Dihydroxyacetone kinase
J4N45_24090	COG0698	ribose 5-phosphate isomerase
J4N45_24100	COG3959	Transketolase, thiamine diphosphate binding domain
J4N45_24105	COG3958	Transketolase
J4N45_24130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J4N45_24135	COG2017	converts alpha-aldose to the beta-anomer
J4N45_24140	COG4608	Belongs to the ABC transporter superfamily
J4N45_24145	COG0444	Belongs to the ABC transporter superfamily
J4N45_24150	COG4166	transmembrane transport
J4N45_24155	COG4239	(ABC) transporter, permease
J4N45_24160	COG4174	ABC transporter (Permease)
J4N45_24170	COG1802	Transcriptional regulator
J4N45_24175	COG0431	NADPH-dependent FMN reductase
J4N45_24175	COG1053	succinate dehydrogenase
J4N45_24175	COG3976	FMN-binding domain protein
J4N45_24185	COG0745	RESPONSE REGULATOR receiver
J4N45_24200	COG2828	Protein conserved in bacteria
J4N45_24250	COG2807	transmembrane transport
J4N45_24260	COG2017	converts alpha-aldose to the beta-anomer
J4N45_24275	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4N45_24290	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
J4N45_24300	COG3250	beta-galactosidase activity
J4N45_24320	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
J4N45_24325	COG1063	alcohol dehydrogenase
J4N45_24330	COG0246	Mannitol dehydrogenase
J4N45_24335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N45_24340	COG0800	Aldolase
J4N45_24345	COG4948	Mandelate Racemase Muconate Lactonizing
J4N45_24360	COG0840	transmembrane signaling receptor activity
J4N45_24385	COG1012	belongs to the aldehyde dehydrogenase family
J4N45_24395	COG2186	Transcriptional regulator
J4N45_24400	COG1012	belongs to the aldehyde dehydrogenase family
J4N45_24415	COG1175	transmembrane transport
J4N45_24420	COG0395	ABC-type sugar transport system, permease component
J4N45_24425	COG2814	Major facilitator Superfamily
J4N45_24465	COG0582	viral genome integration into host DNA
J4N45_24485	COG1960	acyl-CoA dehydrogenase activity
J4N45_24495	COG1012	belongs to the aldehyde dehydrogenase family
J4N45_24500	COG3384	dioxygenase
J4N45_24505	COG0679	Auxin Efflux Carrier
J4N45_24535	COG3971	2-oxopent-4-enoate hydratase activity
J4N45_24555	COG1846	Transcriptional regulator
J4N45_24565	COG4221	oxidoreductase activity
J4N45_24575	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J4N45_24585	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
J4N45_24595	COG0765	amino acid transport
J4N45_24615	COG1278	Cold shock
J4N45_24620	COG4681	YaeQ
J4N45_24630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4N45_24630	COG1017	nitric oxide dioxygenase activity
J4N45_24635	COG3604	Transcriptional regulator
J4N45_24645	COG0519	Catalyzes the synthesis of GMP from XMP
J4N45_24655	COG2850	peptidyl-arginine hydroxylation
J4N45_24665	COG3366	ferrous iron transmembrane transporter activity
J4N45_24670	COG0700	Nucleoside recognition
J4N45_24675	COG0840	transmembrane signaling receptor activity
J4N45_24680	COG0583	DNA-binding transcription factor activity
J4N45_24715	COG4172	Belongs to the ABC transporter superfamily
J4N45_24720	COG4239	(ABC) transporter, permease
J4N45_24725	COG4174	ABC transporter (Permease)
J4N45_24730	COG4166	transmembrane transport
J4N45_24735	COG3706	GGDEF domain
J4N45_24750	COG4580	involved in the transport of maltose and maltodextrins
J4N45_24755	COG1609	Transcriptional regulator
J4N45_24765	COG4608	Belongs to the ABC transporter superfamily
J4N45_24770	COG0444	Belongs to the ABC transporter superfamily
J4N45_24775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N45_24795	COG1472	Belongs to the glycosyl hydrolase 3 family
J4N45_24830	COG1472	Belongs to the glycosyl hydrolase 3 family
J4N45_24835	COG1132	(ABC) transporter
J4N45_24840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N45_24855	COG0028	Belongs to the TPP enzyme family
J4N45_24915	COG1609	Transcriptional regulator
J4N45_24920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N45_24920	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N45_24925	COG1105	Belongs to the carbohydrate kinase PfkB family
J4N45_24930	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
J4N45_24930	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N45_24930	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N45_24940	COG2963	transposase activity
J4N45_24955	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J4N45_24965	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J4N45_24970	COG0509	glycine decarboxylation via glycine cleavage system
J4N45_24990	COG0583	DNA-binding transcription factor activity
J4N45_25020	COG4628	conserved protein (DUF2132)
J4N45_25025	COG0513	Belongs to the DEAD box helicase family
J4N45_25030	COG3842	ATPase activity
J4N45_25035	COG0395	ABC-type sugar transport system, permease component
J4N45_25040	COG1175	transmembrane transport
J4N45_25045	COG1653	transport
J4N45_25050	COG1609	Transcriptional regulator
J4N45_25055	COG0366	Alpha amylase catalytic
J4N45_25080	COG4667	esterase of the alpha-beta hydrolase superfamily
J4N45_25095	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J4N45_25100	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J4N45_25135	COG2188	Transcriptional regulator
J4N45_25145	COG2190	(PTS) system
J4N45_25145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N45_25145	COG1263	PTS System
J4N45_25155	COG1902	pentaerythritol trinitrate reductase activity
J4N45_25160	COG0346	lactoylglutathione lyase activity
J4N45_25165	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
J4N45_25170	COG2207	Transcriptional regulator
J4N45_25185	COG2204	response regulator
J4N45_25190	COG2188	Transcriptional regulator
J4N45_25195	COG2723	6-phospho-beta-galactosidase activity
J4N45_25205	COG2176	DNA-directed DNA polymerase activity
J4N45_25240	COG0697	spore germination
J4N45_25245	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4N45_25250	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4N45_25255	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4N45_25260	COG1447	Phosphotransferase system cellobiose-specific component IIA
J4N45_25265	COG1609	Transcriptional regulator
J4N45_25335	COG0366	Alpha amylase catalytic
J4N45_25360	COG3833	ABC-type maltose transport systems, permease component
J4N45_25365	COG1175	transmembrane transport
J4N45_25375	COG3842	ATPase activity
J4N45_25415	COG2197	response regulator
J4N45_25430	COG0714	Associated with various cellular activities
J4N45_25465	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J4N45_25470	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J4N45_25480	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J4N45_25490	COG1288	antiporter activity
J4N45_25495	COG0697	spore germination
J4N45_25505	COG2197	response regulator
J4N45_25510	COG0583	DNA-binding transcription factor activity
J4N45_25515	COG3706	GGDEF domain
J4N45_25525	COG3069	C4-dicarboxylate transmembrane transporter activity
J4N45_25540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N45_25545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N45_25550	COG1858	cytochrome C peroxidase
J4N45_25555	COG2205	protein histidine kinase activity
J4N45_25555	COG0784	Response regulator, receiver
J4N45_25565	COG3706	GGDEF domain
J4N45_25585	COG4145	pantothenate transmembrane transporter activity
J4N45_25595	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
J4N45_25605	COG1737	Transcriptional regulator
J4N45_25605	COG0837	glucose binding
J4N45_25620	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
J4N45_25625	COG0366	Alpha amylase catalytic
J4N45_25635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4N45_25640	COG0813	purine-nucleoside phosphorylase activity
J4N45_25645	COG0402	S-adenosylhomocysteine deaminase activity
J4N45_25650	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4N45_25655	COG0784	Response regulator, receiver
J4N45_25655	COG0835	chemotaxis
J4N45_25665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4N45_25670	COG2814	Major facilitator Superfamily
J4N45_25675	COG0583	DNA-binding transcription factor activity
J4N45_25685	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J4N45_25705	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4N45_25715	COG1126	abc transporter atp-binding protein
J4N45_25720	COG0765	amino acid transport
J4N45_25725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N45_25730	COG0765	amino acid transport
J4N45_25735	COG0109	protoheme IX farnesyltransferase activity
J4N45_25740	COG1612	heme a metabolic process
J4N45_25760	COG1845	cytochrome c oxidase, subunit III
J4N45_25765	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
J4N45_25770	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J4N45_25775	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J4N45_25785	COG0179	Fumarylacetoacetate (FAA) hydrolase
J4N45_25795	COG1228	amidohydrolase
J4N45_25800	COG0010	Belongs to the arginase family
J4N45_25805	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
J4N45_25810	COG2986	histidine ammonia-lyase
J4N45_25815	COG3397	chitin binding
J4N45_25830	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
J4N45_25835	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J4N45_25840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4N45_25845	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J4N45_25850	COG0402	S-adenosylhomocysteine deaminase activity
J4N45_25855	COG1278	Cold shock
J4N45_25865	COG1166	arginine decarboxylase activity
J4N45_25870	COG0010	Belongs to the arginase family
J4N45_25880	COG3122	Protein conserved in bacteria
J4N45_25890	COG0405	Gamma-glutamyltransferase
J4N45_25900	COG1012	belongs to the aldehyde dehydrogenase family
J4N45_25910	COG1012	belongs to the aldehyde dehydrogenase family
J4N45_25915	COG0019	diaminopimelate decarboxylase activity
J4N45_25945	COG1067	ATP-dependent peptidase activity
J4N45_25965	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
J4N45_25980	COG2264	protein methyltransferase activity
J4N45_26005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4N45_26030	COG0641	radical SAM
J4N45_26045	COG3119	arylsulfatase activity
J4N45_26070	COG4604	ABC transporter, ATP-binding protein
J4N45_26075	COG4605	iron ion homeostasis
J4N45_26080	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N45_26085	COG4607	ABC-type enterochelin transport system periplasmic component
J4N45_26090	COG2188	Transcriptional regulator
J4N45_26095	COG2199	diguanylate cyclase activity
J4N45_26110	COG0488	(ABC) transporter
J4N45_26130	COG0739	heme binding
J4N45_26135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N45_26150	COG3314	Sporulation integral membrane protein YlbJ
J4N45_26170	COG1621	beta-fructofuranosidase activity
J4N45_26175	COG1263	PTS System
J4N45_26175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N45_26180	COG2188	Transcriptional regulator
J4N45_26190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N45_26200	COG0348	domain, Protein
J4N45_26205	COG0437	4 iron, 4 sulfur cluster binding
J4N45_26215	COG0739	heme binding
J4N45_26230	COG1131	(ABC) transporter
J4N45_26235	COG0842	Transport permease protein
J4N45_26240	COG0583	DNA-binding transcription factor activity
J4N45_26250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N45_26260	COG1129	ABC transporter
J4N45_26265	COG4211	Belongs to the binding-protein-dependent transport system permease family
J4N45_26290	COG2738	Putative neutral zinc metallopeptidase
J4N45_26295	COG0673	inositol 2-dehydrogenase activity
J4N45_26300	COG3718	enzyme involved in inositol metabolism
J4N45_26305	COG1082	Xylose isomerase domain protein TIM barrel
J4N45_26325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N45_26330	COG0673	inositol 2-dehydrogenase activity
J4N45_26335	COG3962	Belongs to the TPP enzyme family
J4N45_26345	COG2814	Major facilitator Superfamily
J4N45_26345	COG0477	Major facilitator Superfamily
J4N45_26350	COG0583	DNA-binding transcription factor activity
J4N45_26365	COG0183	Belongs to the thiolase family
J4N45_26395	COG4580	involved in the transport of maltose and maltodextrins
J4N45_26420	COG0583	DNA-binding transcription factor activity
J4N45_26430	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
J4N45_26440	COG0471	metal ion transport
J4N45_26460	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
J4N45_26465	COG0352	thiamine-phosphate diphosphorylase activity
J4N45_26480	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
J4N45_26535	COG0783	Belongs to the Dps family
J4N45_26545	COG0583	DNA-binding transcription factor activity
J4N45_26550	COG4989	oxidoreductase activity
J4N45_26560	COG0534	Mate efflux family protein
J4N45_26575	COG0583	DNA-binding transcription factor activity
J4N45_26580	COG1917	Cupin 2, conserved barrel domain protein
J4N45_26580	COG2207	Transcriptional regulator
J4N45_26595	COG2226	methyltransferase
J4N45_26600	COG1741	Belongs to the pirin family
J4N45_26610	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N45_26625	COG1132	(ABC) transporter
J4N45_26630	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J4N45_26640	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
J4N45_26650	COG0625	glutathione transferase activity
J4N45_26660	COG0737	Belongs to the 5'-nucleotidase family
J4N45_26690	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N45_26705	COG1794	racemase activity, acting on amino acids and derivatives
J4N45_26715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4N45_26720	COG2814	Major facilitator Superfamily
J4N45_26735	COG0346	lactoylglutathione lyase activity
J4N45_26745	COG1227	inorganic diphosphatase activity
J4N45_26760	COG1999	signal sequence binding
J4N45_26770	COG1162	GTPase activity
J4N45_26775	COG2205	protein histidine kinase activity
J4N45_26780	COG0745	RESPONSE REGULATOR receiver
J4N45_26800	COG1960	acyl-CoA dehydrogenase activity
J4N45_26815	COG3243	poly(R)-hydroxyalkanoic acid synthase
J4N45_26825	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
J4N45_26835	COG1522	sequence-specific DNA binding
J4N45_26850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N45_26865	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N45_26865	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N45_26865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N45_26870	COG2207	Transcriptional regulator
J4N45_26880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N45_26885	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N45_26895	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N45_26900	COG2207	Transcriptional regulator
J4N45_26905	COG4303	Ethanolamine ammonia lyase large subunit
J4N45_26915	COG0531	amino acid
J4N45_26925	COG1733	regulation of RNA biosynthetic process
J4N45_26935	COG2814	Major facilitator Superfamily
J4N45_26940	COG3135	benzoate transporter
J4N45_26945	COG1396	sequence-specific DNA binding
J4N45_26955	COG0346	lactoylglutathione lyase activity
J4N45_26960	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J4N45_26965	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J4N45_26980	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N45_26995	COG2723	6-phospho-beta-galactosidase activity
J4N45_27000	COG3265	gluconokinase activity
J4N45_27010	COG1609	Transcriptional regulator
J4N45_27015	COG2723	6-phospho-beta-galactosidase activity
J4N45_27020	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4N45_27030	COG1447	Phosphotransferase system cellobiose-specific component IIA
J4N45_27055	COG3842	ATPase activity
J4N45_27095	COG0259	pyridoxamine-phosphate oxidase activity
J4N45_27125	COG2169	Transcriptional regulator
J4N45_27125	COG1917	Cupin 2, conserved barrel domain protein
J4N45_27130	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
J4N45_27135	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J4N45_27150	COG0786	glutamate:sodium symporter activity
J4N45_27165	COG2084	Dehydrogenase