locus-tag	class	description
J4N38_00010	COG0592	DNA-directed DNA polymerase activity
J4N38_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J4N38_00020	COG0187	DNA topoisomerase II activity
J4N38_00030	COG3977	Valine--pyruvate aminotransferase
J4N38_00040	COG0752	glycyl-tRNA synthetase alpha subunit
J4N38_00045	COG2119	membrane
J4N38_00055	COG0425	Belongs to the sulfur carrier protein TusA family
J4N38_00070	COG0604	alcohol dehydrogenase
J4N38_00080	COG0129	dihydroxy-acid dehydratase activity
J4N38_00085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J4N38_00090	COG3978	acetolactate synthase activity
J4N38_00100	COG0606	chelatase, subunit chli
J4N38_00135	COG0464	growth
J4N38_00140	COG1061	Type III restriction enzyme res subunit
J4N38_00205	COG0204	Acyl-transferase
J4N38_00210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4N38_00215	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J4N38_00225	COG3084	Protein conserved in bacteria
J4N38_00235	COG4326	sporulation control protein
J4N38_00240	COG1272	protein, Hemolysin III
J4N38_00250	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4N38_00255	COG0569	domain protein
J4N38_00260	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J4N38_00260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J4N38_00275	COG0758	DNA mediated transformation
J4N38_00280	COG2922	Belongs to the Smg family
J4N38_00285	COG0551	DNA topoisomerase type I activity
J4N38_00290	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J4N38_00295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J4N38_00305	COG0408	coproporphyrinogen oxidase activity
J4N38_00320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J4N38_00385	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J4N38_00390	COG3300	MHYT domain
J4N38_00390	COG5001	Diguanylate cyclase
J4N38_00400	COG3852	Histidine kinase
J4N38_00405	COG0174	glutamine synthetase
J4N38_00410	COG1217	gtp-binding protein TYPA
J4N38_00425	COG1295	ribonuclease BN
J4N38_00430	COG1490	D-aminoacyl-tRNA deacylase activity
J4N38_00435	COG0456	acetyltransferase
J4N38_00445	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
J4N38_00450	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
J4N38_00455	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J4N38_00460	COG3031	protein transport across the cell outer membrane
J4N38_00470	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4N38_00475	COG1459	type II secretion system
J4N38_00480	COG2165	general secretion pathway protein
J4N38_00485	COG2165	general secretion pathway protein
J4N38_00490	COG2165	general secretion pathway protein
J4N38_00495	COG4795	General secretion pathway protein
J4N38_00500	COG3156	type II secretion system protein K
J4N38_00505	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
J4N38_00510	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
J4N38_00530	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4N38_00540	COG2183	response to ionizing radiation
J4N38_00555	COG1040	competence protein
J4N38_00565	COG0494	nUDIX hydrolase
J4N38_00570	COG1218	3'(2'),5'-bisphosphate nucleotidase
J4N38_00575	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J4N38_00580	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J4N38_00585	COG1561	YicC-like family, N-terminal region
J4N38_00590	COG2252	PERMEase
J4N38_00595	COG0194	GDP metabolic process
J4N38_00600	COG1758	RNA polymerase activity
J4N38_00605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J4N38_00610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4N38_00615	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J4N38_00620	COG1560	Kdo2-lipid A biosynthetic process
J4N38_00625	COG1560	Kdo2-lipid A biosynthetic process
J4N38_00630	COG1309	transcriptional regulator
J4N38_00640	COG2003	Belongs to the UPF0758 family
J4N38_00645	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J4N38_00665	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
J4N38_00670	COG0859	PFAM glycosyl transferase family 9
J4N38_00675	COG0463	Glycosyl transferase, family 2
J4N38_00680	COG0859	PFAM glycosyl transferase family 9
J4N38_00685	COG3642	lipopolysaccharide core region biosynthetic process
J4N38_00735	COG1519	Transferase
J4N38_00750	COG0859	PFAM glycosyl transferase family 9
J4N38_00765	COG3307	-O-antigen
J4N38_00795	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J4N38_00810	COG1132	(ABC) transporter
J4N38_00815	COG1086	Polysaccharide biosynthesis protein
J4N38_00820	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J4N38_00825	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J4N38_00830	COG2089	acid synthase
J4N38_00850	COG1083	cytidylyl-transferase
J4N38_00885	COG1215	transferase activity, transferring glycosyl groups
J4N38_00900	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J4N38_00905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4N38_00910	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
J4N38_00910	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
J4N38_00915	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J4N38_00955	COG1494	fructose-1,6-bisphosphatase
J4N38_00960	COG3074	FtsZ-dependent cytokinesis
J4N38_00965	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J4N38_00970	COG0460	homoserine dehydrogenase
J4N38_00970	COG0527	aspartate kinase activity
J4N38_00975	COG0626	cystathionine gamma-synthase activity
J4N38_00980	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
J4N38_00985	COG0281	malic enzyme
J4N38_00995	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J4N38_01000	COG1609	Transcriptional regulator
J4N38_01005	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J4N38_01010	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
J4N38_01030	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
J4N38_01035	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J4N38_01040	COG1053	succinate dehydrogenase
J4N38_01045	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
J4N38_01050	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N38_01085	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4N38_01100	COG1045	serine acetyltransferase
J4N38_01105	COG1695	Transcriptional regulator
J4N38_01110	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
J4N38_01115	COG1573	uracil-dna glycosylase
J4N38_01120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4N38_01130	COG1253	flavin adenine dinucleotide binding
J4N38_01145	COG0151	Belongs to the GarS family
J4N38_01150	COG0138	bifunctional purine biosynthesis protein purh
J4N38_01155	COG0789	Transcriptional regulator
J4N38_01160	COG2199	diguanylate cyclase activity
J4N38_01165	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
J4N38_01170	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4N38_01175	COG2264	protein methyltransferase activity
J4N38_01180	COG0439	Biotin carboxylase
J4N38_01185	COG0511	ligase activity, forming carbon-carbon bonds
J4N38_01190	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J4N38_01195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J4N38_01210	COG2814	Major facilitator Superfamily
J4N38_01215	COG0784	Response regulator, receiver
J4N38_01215	COG2205	protein histidine kinase activity
J4N38_01220	COG1072	(Pantothenic acid kinase))
J4N38_01250	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J4N38_01255	COG0250	Participates in transcription elongation, termination and antitermination
J4N38_01270	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J4N38_01280	COG0085	RNA polymerase activity
J4N38_01285	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J4N38_01290	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J4N38_01295	COG1027	Aspartate ammonia-lyase
J4N38_01370	COG0512	Glutamine amidotransferase of anthranilate synthase
J4N38_01375	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J4N38_01385	COG1012	belongs to the aldehyde dehydrogenase family
J4N38_01395	COG0688	phosphatidylethanolamine metabolic process
J4N38_01400	COG1162	GTPase activity
J4N38_01455	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J4N38_01460	COG0802	atpase or kinase
J4N38_01465	COG0860	N-Acetylmuramoyl-L-alanine amidase
J4N38_01470	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J4N38_01485	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J4N38_01490	COG0330	HflC and HflK could
J4N38_01495	COG0330	HflC and HflK could
J4N38_01500	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
J4N38_01505	COG2900	Belongs to the SlyX family
J4N38_01515	COG0545	Peptidyl-prolyl cis-trans isomerase
J4N38_01520	COG2964	Protein conserved in bacteria
J4N38_01525	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
J4N38_01530	COG2923	Belongs to the DsrF TusC family
J4N38_01535	COG2168	tRNA wobble position uridine thiolation
J4N38_01545	COG0049	tRNA binding
J4N38_01550	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J4N38_01555	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J4N38_01560	COG2906	2 iron, 2 sulfur cluster binding
J4N38_01570	COG0360	Binds together with S18 to 16S ribosomal RNA
J4N38_01590	COG0305	Participates in initiation and elongation during chromosome replication
J4N38_01595	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J4N38_01600	COG0432	Pfam Uncharacterised protein family UPF0047
J4N38_01625	COG1136	(ABC) transporter
J4N38_01640	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
J4N38_01650	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N38_01655	COG0729	surface antigen
J4N38_01660	COG2911	Protein conserved in bacteria
J4N38_01665	COG2105	PFAM AIG2 family protein
J4N38_01670	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J4N38_01680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J4N38_01685	COG0163	prenyltransferase activity
J4N38_01690	COG4143	(ABC) transporter
J4N38_01695	COG1178	ABC-type Fe3 transport system permease component
J4N38_01700	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
J4N38_01710	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J4N38_01725	COG0629	single-stranded DNA binding
J4N38_01730	COG2200	EAL domain
J4N38_01730	COG2199	diguanylate cyclase activity
J4N38_01755	COG3409	Peptidoglycan-binding domain 1 protein
J4N38_01755	COG3267	Type II secretory pathway component ExeA
J4N38_01765	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4N38_01770	COG1459	type II secretion system
J4N38_01780	COG2165	general secretion pathway protein
J4N38_01785	COG2165	general secretion pathway protein
J4N38_01815	COG1077	Cell shape determining protein MreB Mrl
J4N38_01820	COG1792	Involved in formation and maintenance of cell shape
J4N38_01825	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
J4N38_01830	COG0424	maF-like protein
J4N38_01840	COG3164	Protein of unknown function
J4N38_01845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J4N38_01850	COG0312	modulator of DNA gyrase
J4N38_01905	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
J4N38_01915	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J4N38_01920	COG2066	Belongs to the glutaminase family
J4N38_01925	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J4N38_01930	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J4N38_01965	COG0762	integral membrane protein
J4N38_01970	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J4N38_01975	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J4N38_01990	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J4N38_01995	COG1678	Uncharacterized ACR, COG1678
J4N38_02000	COG0189	ligase activity
J4N38_02005	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J4N38_02010	COG2356	endonuclease I
J4N38_02015	COG3091	SprT-like family
J4N38_02025	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J4N38_02035	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J4N38_02045	COG0191	fructose-bisphosphate aldolase activity
J4N38_02050	COG0668	transmembrane transport
J4N38_02065	COG0583	DNA-binding transcription factor activity
J4N38_02075	COG3706	GGDEF domain
J4N38_02085	COG0469	pyruvate kinase activity
J4N38_02090	COG1349	DNA-binding transcription factor activity
J4N38_02095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J4N38_02120	COG0028	Belongs to the TPP enzyme family
J4N38_02125	COG1022	Amp-dependent synthetase and ligase
J4N38_02130	COG0583	DNA-binding transcription factor activity
J4N38_02145	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J4N38_02150	COG0473	3-isopropylmalate dehydrogenase activity
J4N38_02165	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J4N38_02170	COG1349	DNA-binding transcription factor activity
J4N38_02175	COG0469	pyruvate kinase activity
J4N38_02185	COG3706	GGDEF domain
J4N38_02195	COG0583	DNA-binding transcription factor activity
J4N38_02220	COG0191	fructose-bisphosphate aldolase activity
J4N38_02225	COG0668	transmembrane transport
J4N38_02240	COG0583	DNA-binding transcription factor activity
J4N38_02250	COG3706	GGDEF domain
J4N38_02260	COG0469	pyruvate kinase activity
J4N38_02265	COG1349	DNA-binding transcription factor activity
J4N38_02270	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J4N38_02290	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J4N38_02305	COG0583	DNA-binding transcription factor activity
J4N38_02310	COG1022	Amp-dependent synthetase and ligase
J4N38_02315	COG0028	Belongs to the TPP enzyme family
J4N38_02320	COG0440	acetolactate synthase activity
J4N38_02325	COG0584	glycerophosphoryl diester phosphodiesterase
J4N38_02330	COG2271	Major facilitator Superfamily
J4N38_02335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4N38_02345	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J4N38_02360	COG3079	Belongs to the UPF0149 family
J4N38_02365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N38_02370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N38_02385	COG0354	folic acid binding
J4N38_02390	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J4N38_02395	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J4N38_02400	COG1595	DNA-templated transcription, initiation
J4N38_02410	COG3026	antisigma factor binding
J4N38_02415	COG3086	response to oxidative stress
J4N38_02420	COG0481	GTPase activity
J4N38_02430	COG0571	ribonuclease III activity
J4N38_02435	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J4N38_02440	COG1381	Involved in DNA repair and RecF pathway recombination
J4N38_02445	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J4N38_02450	COG0736	holo-[acyl-carrier-protein] synthase activity
J4N38_02455	COG4999	Histidine kinase
J4N38_02455	COG3850	Histidine kinase
J4N38_02455	COG3437	response regulator, receiver
J4N38_02455	COG2205	protein histidine kinase activity
J4N38_02460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J4N38_02465	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J4N38_02470	COG3956	TIGRFAM MazG family protein
J4N38_02480	COG0148	phosphopyruvate hydratase activity
J4N38_02485	COG0617	tRNA 3'-terminal CCA addition
J4N38_02490	COG3267	Type II secretory pathway component ExeA
J4N38_02490	COG3409	Peptidoglycan-binding domain 1 protein
J4N38_02500	COG4991	sh3 domain protein
J4N38_02505	COG0306	phosphate transporter
J4N38_02510	COG1392	Phosphate transport regulator
J4N38_02515	COG3025	triphosphatase activity
J4N38_02520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N38_02530	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J4N38_02535	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J4N38_02535	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J4N38_02540	COG0745	RESPONSE REGULATOR receiver
J4N38_02550	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J4N38_02565	COG0083	homoserine kinase activity
J4N38_02570	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J4N38_02575	COG2860	membrane
J4N38_02590	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J4N38_02595	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J4N38_02615	COG0534	Mate efflux family protein
J4N38_02620	COG2204	response regulator
J4N38_02630	COG0667	Aldo Keto reductase
J4N38_02640	COG3066	DNA modification
J4N38_02645	COG0494	nUDIX hydrolase
J4N38_02655	COG0730	response to heat
J4N38_02660	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J4N38_02665	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J4N38_02670	COG1283	sodium-dependent phosphate transmembrane transporter activity
J4N38_02675	COG0583	DNA-binding transcription factor activity
J4N38_02680	COG0640	Transcriptional regulator
J4N38_02685	COG0268	Binds directly to 16S ribosomal RNA
J4N38_02690	COG0728	peptidoglycan biosynthetic process
J4N38_02695	COG0196	riboflavin kinase activity
J4N38_02710	COG1047	Peptidyl-prolyl cis-trans
J4N38_02715	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J4N38_02720	COG1966	Carbon starvation protein
J4N38_02730	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
J4N38_02735	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
J4N38_02740	COG2971	BadF BadG BcrA BcrD
J4N38_02750	COG1737	Transcriptional regulator
J4N38_02760	COG3279	Response regulator of the LytR AlgR family
J4N38_02765	COG3275	phosphorelay sensor kinase activity
J4N38_02770	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4N38_02775	COG0287	Prephenate dehydrogenase
J4N38_02775	COG1605	Chorismate mutase
J4N38_02780	COG0739	heme binding
J4N38_02790	COG0488	(ABC) transporter
J4N38_02795	COG0741	lytic transglycosylase activity
J4N38_02800	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
J4N38_02805	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
J4N38_02810	COG5001	Diguanylate cyclase
J4N38_02815	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J4N38_02820	COG1605	Chorismate mutase
J4N38_02820	COG0077	Prephenate dehydratase
J4N38_02825	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J4N38_02830	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
J4N38_02835	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N38_02840	COG0564	pseudouridine synthase activity
J4N38_02845	COG1496	oxidoreductase activity
J4N38_02850	COG0542	response to heat
J4N38_02895	COG0483	inositol monophosphate 1-phosphatase activity
J4N38_02900	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
J4N38_02910	COG1104	cysteine desulfurase activity
J4N38_02915	COG0822	iron-sulfur transferase activity
J4N38_02930	COG0443	Heat shock 70 kDa protein
J4N38_02935	COG0633	Ferredoxin
J4N38_02940	COG2975	iron-sulfur cluster assembly
J4N38_02955	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J4N38_02960	COG0583	DNA-binding transcription factor activity
J4N38_02970	COG0583	DNA-binding transcription factor activity
J4N38_02975	COG1022	Amp-dependent synthetase and ligase
J4N38_02980	COG2169	Transcriptional regulator
J4N38_03010	COG4964	Belongs to the GSP D family
J4N38_03060	COG2059	Chromate
J4N38_03065	COG0583	DNA-binding transcription factor activity
J4N38_03075	COG2169	Transcriptional regulator
J4N38_03080	COG1486	melibiose metabolic process
J4N38_03085	COG2211	Major facilitator Superfamily
J4N38_03095	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4N38_03100	COG1085	galactose-1-phosphate uridylyltransferase
J4N38_03110	COG2017	converts alpha-aldose to the beta-anomer
J4N38_03115	COG1609	Transcriptional regulator
J4N38_03125	COG2211	Major facilitator Superfamily
J4N38_03150	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_03150	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_03150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N38_03160	COG2171	N-acyltransferase activity
J4N38_03165	COG0450	alkyl hydroperoxide reductase
J4N38_03170	COG0583	DNA-binding transcription factor activity
J4N38_03175	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J4N38_03200	COG0517	IMP dehydrogenase activity
J4N38_03205	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J4N38_03215	COG1862	Preprotein translocase
J4N38_03220	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N38_03225	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N38_03245	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J4N38_03250	COG0826	peptidase U32
J4N38_03260	COG0745	RESPONSE REGULATOR receiver
J4N38_03265	COG5002	protein histidine kinase activity
J4N38_03275	COG0248	Ppx GppA phosphatase
J4N38_03280	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J4N38_03290	COG0581	inorganic phosphate transmembrane transporter activity
J4N38_03295	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4N38_03300	COG0704	Plays a role in the regulation of phosphate uptake
J4N38_03320	COG3141	response to X-ray
J4N38_03335	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J4N38_03340	COG1074	ATP-dependent DNA helicase activity
J4N38_03345	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J4N38_03365	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
J4N38_03370	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J4N38_03375	COG2166	iron-sulfur cluster assembly
J4N38_03390	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J4N38_03395	COG0124	histidyl-tRNA synthetase
J4N38_03400	COG2976	Protein conserved in bacteria
J4N38_03405	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N38_03410	COG1160	GTP binding
J4N38_03415	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J4N38_03430	COG0517	IMP dehydrogenase activity
J4N38_03430	COG0516	GMP reductase activity
J4N38_03445	COG1584	GPR1 FUN34 yaaH family protein
J4N38_03450	COG1115	amino acid carrier protein
J4N38_03460	COG0583	DNA-binding transcription factor activity
J4N38_03475	COG0784	Response regulator, receiver
J4N38_03475	COG0835	chemotaxis
J4N38_03480	COG0204	Acyl-transferase
J4N38_03495	COG0527	aspartate kinase activity
J4N38_03500	COG3706	GGDEF domain
J4N38_03500	COG2203	Gaf domain
J4N38_03500	COG5001	Diguanylate cyclase
J4N38_03500	COG4251	negative regulation of phosphorylation
J4N38_03505	COG3706	GGDEF domain
J4N38_03515	COG2239	Acts as a magnesium transporter
J4N38_03520	COG0189	ligase activity
J4N38_03520	COG4067	protein conserved in archaea
J4N38_03525	COG0189	ligase activity
J4N38_03545	COG2867	negative regulation of translational initiation
J4N38_03550	COG2914	Belongs to the UPF0125 (RnfH) family
J4N38_03555	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N38_03560	COG0497	DNA recombination
J4N38_03565	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J4N38_03570	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J4N38_03580	COG0443	Heat shock 70 kDa protein
J4N38_03615	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J4N38_03625	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
J4N38_03630	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J4N38_03630	COG0047	phosphoribosylformylglycinamidine synthase activity
J4N38_03655	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J4N38_03660	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J4N38_03665	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J4N38_03670	COG1187	pseudouridine synthase activity
J4N38_03675	COG2840	Smr protein MutS2
J4N38_03700	COG3104	oligopeptide transport
J4N38_03705	COG0367	asparagine synthase
J4N38_03710	COG4651	solute:proton antiporter activity
J4N38_03710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J4N38_03715	COG1940	carbohydrate kinase activity
J4N38_03715	COG1846	Transcriptional regulator
J4N38_03720	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J4N38_03725	COG1263	PTS System
J4N38_03725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N38_03725	COG2190	(PTS) system
J4N38_03760	COG0330	HflC and HflK could
J4N38_03765	COG3118	belongs to the thioredoxin family
J4N38_03770	COG0300	oxidoreductase activity
J4N38_03775	COG1090	epimerase
J4N38_03800	COG0622	Phosphoesterase
J4N38_03820	COG3710	Transcriptional regulator
J4N38_03825	COG0326	Molecular chaperone. Has ATPase activity
J4N38_03835	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J4N38_03845	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4N38_03850	COG1611	Belongs to the LOG family
J4N38_03865	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J4N38_03865	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J4N38_03875	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
J4N38_03890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J4N38_03895	COG1393	Belongs to the ArsC family
J4N38_03920	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
J4N38_03930	COG0437	4 iron, 4 sulfur cluster binding
J4N38_03935	COG3301	Polysulphide reductase, NrfD
J4N38_03940	COG1138	Cytochrome C-type biogenesis protein
J4N38_03945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4N38_03950	COG4235	cytochrome complex assembly
J4N38_03950	COG3088	subunit of a heme lyase
J4N38_03960	COG2837	iron assimilation
J4N38_03965	COG2027	D-alanyl-D-alanine carboxypeptidase
J4N38_03975	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J4N38_03980	COG0739	heme binding
J4N38_03995	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N38_04005	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J4N38_04015	COG1516	flagellar protein fliS
J4N38_04035	COG1677	Flagellar hook-basal body complex protein FliE
J4N38_04045	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J4N38_04095	COG1987	bacterial-type flagellum assembly
J4N38_04100	COG1684	flagellar biosynthetic protein fliR
J4N38_04115	COG2890	protein-(glutamine-N5) methyltransferase activity
J4N38_04120	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J4N38_04130	COG2860	membrane
J4N38_04135	COG3101	peptidyl-lysine hydroxylation
J4N38_04160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J4N38_04165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4N38_04170	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J4N38_04180	COG0101	tRNA pseudouridine synthase activity
J4N38_04185	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J4N38_04190	COG0285	dihydrofolate synthase activity
J4N38_04195	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
J4N38_04200	COG1286	toxin biosynthetic process
J4N38_04205	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J4N38_04210	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J4N38_04215	COG1121	(ABC) transporter
J4N38_04220	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
J4N38_04225	COG4977	sequence-specific DNA binding
J4N38_04230	COG1918	ferrous iron import across plasma membrane
J4N38_04235	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J4N38_04255	COG3102	Protein conserved in bacteria
J4N38_04260	COG1025	Belongs to the peptidase M16 family
J4N38_04265	COG2062	phosphohistidine phosphatase, SixA
J4N38_04295	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
J4N38_04300	COG2198	Histidine kinase
J4N38_04300	COG0643	Histidine kinase
J4N38_04300	COG0784	Response regulator, receiver
J4N38_04305	COG2201	protein-glutamate methylesterase activity
J4N38_04310	COG1192	Involved in chromosome partitioning
J4N38_04320	COG0835	chemotaxis
J4N38_04330	COG4133	protoheme IX ABC transporter activity
J4N38_04335	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4N38_04340	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4N38_04345	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4N38_04355	COG1138	Cytochrome C-type biogenesis protein
J4N38_04360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4N38_04375	COG2853	Lipoprotein
J4N38_04380	COG2067	long-chain fatty acid transport protein
J4N38_04385	COG2067	long-chain fatty acid transport protein
J4N38_04400	COG0183	Belongs to the thiolase family
J4N38_04410	COG0778	Nitroreductase
J4N38_04415	COG0583	DNA-binding transcription factor activity
J4N38_04420	COG0745	RESPONSE REGULATOR receiver
J4N38_04425	COG2832	Protein of unknown function (DUF454)
J4N38_04430	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J4N38_04445	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J4N38_04450	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J4N38_04475	COG1653	transport
J4N38_04480	COG1175	transmembrane transport
J4N38_04490	COG3842	ATPase activity
J4N38_04495	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J4N38_04500	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J4N38_04505	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N38_04515	COG2204	response regulator
J4N38_04535	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J4N38_04540	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J4N38_04545	COG0776	regulation of translation
J4N38_04550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4N38_04555	COG1555	photosystem II stabilization
J4N38_04560	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J4N38_04565	COG0539	negative regulation of cytoplasmic translation
J4N38_04575	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
J4N38_04580	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
J4N38_04585	COG0284	orotidine-5'-phosphate decarboxylase activity
J4N38_04615	COG4120	Belongs to the binding-protein-dependent transport system permease family
J4N38_04625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4N38_04640	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J4N38_04645	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J4N38_04650	COG0252	asparaginase activity
J4N38_04655	COG0616	signal peptide processing
J4N38_04660	COG0446	pyridine nucleotide-disulphide oxidoreductase
J4N38_04660	COG1902	pentaerythritol trinitrate reductase activity
J4N38_04665	COG0788	formyltetrahydrofolate deformylase activity
J4N38_04675	COG1199	ATP-dependent helicase activity
J4N38_04680	COG1214	PFAM Peptidase M22, glycoprotease
J4N38_04695	COG0596	Alpha beta hydrolase
J4N38_04700	COG0318	PFAM AMP-dependent synthetase and ligase
J4N38_04705	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
J4N38_04710	COG0659	secondary active sulfate transmembrane transporter activity
J4N38_04715	COG1530	ribonuclease E activity
J4N38_04720	COG0564	pseudouridine synthase activity
J4N38_04730	COG1399	metal-binding, possibly nucleic acid-binding protein
J4N38_04735	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J4N38_04745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J4N38_04770	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J4N38_04775	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J4N38_04780	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J4N38_04785	COG0470	DNA polymerase III
J4N38_04790	COG0084	hydrolase, TatD family'
J4N38_04795	COG1263	PTS System
J4N38_04795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N38_04810	COG0733	neurotransmitter:sodium symporter activity
J4N38_04825	COG4667	esterase of the alpha-beta hydrolase superfamily
J4N38_04830	COG0702	epimerase
J4N38_04850	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J4N38_04855	COG0840	transmembrane signaling receptor activity
J4N38_04860	COG0632	four-way junction helicase activity
J4N38_04865	COG2255	four-way junction helicase activity
J4N38_04870	COG1271	oxidase subunit
J4N38_04875	COG1294	oxidase, subunit
J4N38_04880	COG4890	Cyd operon protein YbgT
J4N38_04890	COG0824	Thioesterase
J4N38_04895	COG0811	peptide transport
J4N38_04910	COG0823	Involved in the tonB-independent uptake of proteins
J4N38_04915	COG2885	chlorophyll binding
J4N38_04920	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
J4N38_04925	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J4N38_04940	COG2205	protein histidine kinase activity
J4N38_04940	COG0784	Response regulator, receiver
J4N38_04955	COG1401	restriction endodeoxyribonuclease activity
J4N38_04975	COG1902	pentaerythritol trinitrate reductase activity
J4N38_04980	COG1881	PFAM PEBP family protein
J4N38_04995	COG1940	carbohydrate kinase activity
J4N38_05015	COG1960	acyl-CoA dehydrogenase activity
J4N38_05020	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J4N38_05030	COG0708	Exodeoxyribonuclease III
J4N38_05035	COG0840	transmembrane signaling receptor activity
J4N38_05040	COG2850	peptidyl-arginine hydroxylation
J4N38_05055	COG0730	response to heat
J4N38_05060	COG1199	ATP-dependent helicase activity
J4N38_05075	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J4N38_05085	COG0156	8-amino-7-oxononanoate synthase activity
J4N38_05090	COG1073	alpha beta
J4N38_05090	COG2226	methyltransferase
J4N38_05095	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J4N38_05105	COG0501	Belongs to the peptidase M48B family
J4N38_05115	COG1028	Short-chain dehydrogenase reductase Sdr
J4N38_05130	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J4N38_05140	COG2268	Band 7 protein
J4N38_05150	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J4N38_05160	COG0482	sulfurtransferase activity
J4N38_05170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N38_05180	COG1757	Na H antiporter
J4N38_05190	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J4N38_05200	COG0131	Imidazoleglycerol-phosphate dehydratase
J4N38_05200	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J4N38_05205	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J4N38_05210	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J4N38_05220	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J4N38_05220	COG0140	phosphoribosyl-ATP diphosphatase activity
J4N38_05225	COG2199	diguanylate cyclase activity
J4N38_05225	COG2200	EAL domain
J4N38_05225	COG2202	Pas domain
J4N38_05230	COG0784	Response regulator, receiver
J4N38_05230	COG2205	protein histidine kinase activity
J4N38_05250	COG1227	inorganic diphosphatase activity
J4N38_05260	COG4172	Belongs to the ABC transporter superfamily
J4N38_05270	COG4171	peptide transport system, permease
J4N38_05285	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
J4N38_05290	COG1842	Phage shock protein A
J4N38_05320	COG2818	Glycosylase
J4N38_05330	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J4N38_05335	COG0626	cystathionine gamma-synthase activity
J4N38_05345	COG0733	neurotransmitter:sodium symporter activity
J4N38_05350	COG0564	pseudouridine synthase activity
J4N38_05355	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J4N38_05365	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J4N38_05370	COG4136	ATPase activity
J4N38_05375	COG4135	transport system, permease component
J4N38_05380	COG4134	Bacterial extracellular solute-binding protein
J4N38_05390	COG3313	Fe-S protein
J4N38_05405	COG2350	Protein conserved in bacteria
J4N38_05440	COG0776	regulation of translation
J4N38_05450	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J4N38_05460	COG0417	DNA replication proofreading
J4N38_05475	COG2197	response regulator
J4N38_05480	COG0322	excinuclease ABC activity
J4N38_05510	COG1902	pentaerythritol trinitrate reductase activity
J4N38_05520	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J4N38_05530	COG1032	radical SAM domain protein
J4N38_05555	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J4N38_05565	COG1764	response to oxidative stress
J4N38_05570	COG1846	Transcriptional regulator
J4N38_05580	COG0583	DNA-binding transcription factor activity
J4N38_05605	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J4N38_05655	COG0443	Heat shock 70 kDa protein
J4N38_05695	COG1643	Atp-dependent helicase
J4N38_05710	COG0159	tryptophan synthase activity
J4N38_05720	COG0134	indole-3-glycerol-phosphate synthase activity
J4N38_05720	COG0135	phosphoribosylanthranilate isomerase activity
J4N38_05725	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J4N38_05730	COG0512	Glutamine amidotransferase of anthranilate synthase
J4N38_05735	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J4N38_05745	COG0613	PHP domain protein
J4N38_05750	COG0009	L-threonylcarbamoyladenylate synthase
J4N38_05765	COG1187	pseudouridine synthase activity
J4N38_05770	COG0384	phenazine biosynthesis protein PhzF
J4N38_05775	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J4N38_05780	COG4988	ABC transporter
J4N38_05785	COG0492	ferredoxin-NADP+ reductase activity
J4N38_05800	COG0612	Peptidase, M16
J4N38_05810	COG2949	membrane
J4N38_05820	COG0281	malic enzyme
J4N38_05825	COG1643	Atp-dependent helicase
J4N38_05840	COG1448	Aminotransferase
J4N38_05845	COG2770	Histidine kinase
J4N38_05845	COG3437	response regulator, receiver
J4N38_05855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N38_05865	COG0017	Asparaginyl-tRNA synthetase
J4N38_05870	COG0840	transmembrane signaling receptor activity
J4N38_05875	COG0720	synthase
J4N38_05880	COG0814	amino acid
J4N38_05890	COG1760	l-serine dehydratase
J4N38_05895	COG0814	amino acid
J4N38_05900	COG0494	nUDIX hydrolase
J4N38_05915	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J4N38_05930	COG3106	COG3106 Predicted ATPase
J4N38_05945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N38_05975	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J4N38_06000	COG2989	Protein conserved in bacteria
J4N38_06005	COG3108	Peptidase M15
J4N38_06010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4N38_06025	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J4N38_06055	COG0783	Belongs to the Dps family
J4N38_06065	COG0531	amino acid
J4N38_06070	COG2962	Rard protein
J4N38_06095	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J4N38_06105	COG1942	4-Oxalocrotonate Tautomerase
J4N38_06200	COG0346	lactoylglutathione lyase activity
J4N38_06370	COG0251	oxidation-reduction process
J4N38_06405	COG1028	Short-chain dehydrogenase reductase Sdr
J4N38_06470	COG4628	conserved protein (DUF2132)
J4N38_06680	COG3385	transposase activity
J4N38_06815	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J4N38_06855	COG3755	Protein conserved in bacteria
J4N38_06885	COG0384	phenazine biosynthesis protein PhzF
J4N38_07000	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J4N38_07075	COG0384	phenazine biosynthesis protein PhzF
J4N38_07130	COG3385	transposase activity
J4N38_07155	COG1280	lysine exporter protein (LysE YggA)
J4N38_07160	COG2161	toxin-antitoxin pair type II binding
J4N38_07165	COG4115	mRNA cleavage
J4N38_07185	COG0384	phenazine biosynthesis protein PhzF
J4N38_07265	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
J4N38_07275	COG0625	glutathione transferase activity
J4N38_07290	COG2885	chlorophyll binding
J4N38_07305	COG0247	lactate metabolic process
J4N38_07305	COG0277	FAD linked oxidase domain protein
J4N38_07320	COG2986	histidine ammonia-lyase
J4N38_07330	COG0010	Belongs to the arginase family
J4N38_07335	COG1228	amidohydrolase
J4N38_07340	COG2188	Transcriptional regulator
J4N38_07345	COG4326	sporulation control protein
J4N38_07365	COG0500	methyltransferase
J4N38_07370	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J4N38_07380	COG0295	cytidine deaminase activity
J4N38_07385	COG1346	cytolysis
J4N38_07390	COG1380	Effector of murein hydrolase LrgA
J4N38_07395	COG2925	Exonuclease
J4N38_07400	COG1823	symporter activity
J4N38_07405	COG0702	epimerase
J4N38_07410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J4N38_07415	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J4N38_07420	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J4N38_07440	COG4139	cobalamin transport
J4N38_07445	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
J4N38_07470	COG0583	DNA-binding transcription factor activity
J4N38_07475	COG1119	ATPase activity
J4N38_07485	COG2205	protein histidine kinase activity
J4N38_07485	COG0784	Response regulator, receiver
J4N38_07495	COG1451	nucleotide metabolic process
J4N38_07515	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4N38_07515	COG0596	Alpha beta hydrolase
J4N38_07520	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
J4N38_07535	COG2200	EAL domain
J4N38_07550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N38_07575	COG0515	serine threonine protein kinase
J4N38_07690	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
J4N38_07695	COG0372	Belongs to the citrate synthase family
J4N38_07705	COG2828	Protein conserved in bacteria
J4N38_07725	COG0561	phosphatase activity
J4N38_07730	COG0602	queuosine metabolic process
J4N38_07765	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J4N38_07770	COG0840	transmembrane signaling receptor activity
J4N38_07775	COG1254	Belongs to the acylphosphatase family
J4N38_07780	COG2920	part of a sulfur-relay system
J4N38_07785	COG0670	Belongs to the BI1 family
J4N38_07790	COG1126	abc transporter atp-binding protein
J4N38_07795	COG0765	amino acid transport
J4N38_07800	COG4597	amino acid ABC transporter
J4N38_07805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N38_07810	COG1648	precorrin-2 dehydrogenase activity
J4N38_07810	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J4N38_07820	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4N38_07825	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J4N38_07845	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
J4N38_07845	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J4N38_07850	COG3008	intermembrane lipid transfer
J4N38_07855	COG2995	paraquat-inducible protein a
J4N38_07860	COG1132	(ABC) transporter
J4N38_07865	COG1956	GAF domain-containing protein
J4N38_07870	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
J4N38_07885	COG0308	aminopeptidase N
J4N38_07900	COG0167	dihydroorotate dehydrogenase activity
J4N38_07910	COG0116	Belongs to the methyltransferase superfamily
J4N38_07910	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J4N38_07920	COG0488	(ABC) transporter
J4N38_07935	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J4N38_07940	COG1067	ATP-dependent peptidase activity
J4N38_07945	COG3120	sequence-specific DNA binding
J4N38_07990	COG0840	transmembrane signaling receptor activity
J4N38_07995	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J4N38_08135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4N38_08150	COG3278	Belongs to the heme-copper respiratory oxidase family
J4N38_08165	COG2010	Cytochrome c
J4N38_08175	COG2217	Heavy metal translocating P-type atpase
J4N38_08190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N38_08195	COG0589	response to stress
J4N38_08220	COG3842	ATPase activity
J4N38_08230	COG1177	transmembrane transport
J4N38_08235	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J4N38_08245	COG2199	diguanylate cyclase activity
J4N38_08250	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J4N38_08265	COG0583	DNA-binding transcription factor activity
J4N38_08280	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
J4N38_08315	COG0488	(ABC) transporter
J4N38_08325	COG1595	DNA-templated transcription, initiation
J4N38_08335	COG1910	domain protein
J4N38_08340	COG0746	molybdenum cofactor guanylyltransferase activity
J4N38_08345	COG1763	Mo-molybdopterin cofactor biosynthetic process
J4N38_08375	COG1940	carbohydrate kinase activity
J4N38_08380	COG3148	PFAM DTW domain containing protein
J4N38_08390	COG0840	transmembrane signaling receptor activity
J4N38_08390	COG3290	protein histidine kinase activity
J4N38_08395	COG0791	NLP P60 protein
J4N38_08405	COG3001	Fructosamine kinase
J4N38_08415	COG0307	riboflavin synthase, alpha
J4N38_08420	COG0534	Mate efflux family protein
J4N38_08465	COG2204	response regulator
J4N38_08475	COG0438	transferase activity, transferring glycosyl groups
J4N38_08510	COG0297	glycogen (starch) synthase activity
J4N38_08520	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J4N38_08540	COG1196	nuclear chromosome segregation
J4N38_08555	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
J4N38_08600	COG3293	Transposase
J4N38_08630	COG4774	siderophore transport
J4N38_08650	COG4615	Cyclic peptide transporter
J4N38_08660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4N38_08665	COG1120	ATPase activity
J4N38_08670	COG2977	Belongs to the P-Pant transferase superfamily
J4N38_08675	COG1929	Belongs to the glycerate kinase type-1 family
J4N38_08680	COG3835	regulator
J4N38_08685	COG0583	DNA-binding transcription factor activity
J4N38_08695	COG3385	transposase activity
J4N38_08700	COG3713	MltA-interacting MipA family protein
J4N38_08705	COG2205	protein histidine kinase activity
J4N38_08710	COG0745	RESPONSE REGULATOR receiver
J4N38_08730	COG2116	formate transmembrane transporter activity
J4N38_08740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4N38_08745	COG2199	diguanylate cyclase activity
J4N38_08750	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4N38_08775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N38_08780	COG0454	-acetyltransferase
J4N38_08825	COG3122	Protein conserved in bacteria
J4N38_08845	COG4565	transcriptional regulatory protein
J4N38_08850	COG3290	protein histidine kinase activity
J4N38_08870	COG0848	biopolymer transport protein
J4N38_08875	COG0811	peptide transport
J4N38_08880	COG0811	peptide transport
J4N38_08915	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J4N38_08920	COG1328	CTP reductase activity
J4N38_08925	COG0840	transmembrane signaling receptor activity
J4N38_08935	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4N38_08940	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4N38_08945	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4N38_08950	COG0633	Ferredoxin
J4N38_08975	COG0019	diaminopimelate decarboxylase activity
J4N38_09000	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J4N38_09010	COG0577	efflux transmembrane transporter activity
J4N38_09015	COG1136	(ABC) transporter
J4N38_09020	COG0534	Mate efflux family protein
J4N38_09025	COG0702	epimerase
J4N38_09035	COG2814	Major facilitator Superfamily
J4N38_09045	COG1061	Type III restriction enzyme res subunit
J4N38_09085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N38_09090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N38_09105	COG0463	Glycosyl transferase, family 2
J4N38_09155	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J4N38_09205	COG0242	peptide deformylase activity
J4N38_09210	COG0519	Catalyzes the synthesis of GMP from XMP
J4N38_09220	COG4580	involved in the transport of maltose and maltodextrins
J4N38_09225	COG3040	lipid binding
J4N38_09235	COG2824	Alkylphosphonate utilization operon protein PhnA
J4N38_09285	COG1115	amino acid carrier protein
J4N38_09290	COG1280	lysine exporter protein (LysE YggA)
J4N38_09295	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
J4N38_09300	COG0352	thiamine-phosphate diphosphorylase activity
J4N38_09315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N38_09325	COG1012	belongs to the aldehyde dehydrogenase family
J4N38_09335	COG0583	DNA-binding transcription factor activity
J4N38_09355	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J4N38_09365	COG1609	Transcriptional regulator
J4N38_09370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J4N38_09380	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J4N38_09380	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N38_09395	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N38_09400	COG1609	Transcriptional regulator
J4N38_09415	COG1278	Cold shock
J4N38_09440	COG1538	Outer membrane efflux protein
J4N38_09445	COG1858	cytochrome C peroxidase
J4N38_09450	COG2205	protein histidine kinase activity
J4N38_09450	COG0784	Response regulator, receiver
J4N38_09465	COG0277	FAD linked oxidase domain protein
J4N38_09470	COG0583	DNA-binding transcription factor activity
J4N38_09490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N38_09530	COG0072	phenylalanine-tRNA ligase activity
J4N38_09530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4N38_09560	COG2133	pyrroloquinoline quinone binding
J4N38_09570	COG4191	Histidine kinase
J4N38_09585	COG3070	regulator of competence-specific genes
J4N38_09595	COG2431	L-lysine efflux transmembrane transporter activity
J4N38_09605	COG0076	glutamate decarboxylase activity
J4N38_09610	COG1737	Transcriptional regulator
J4N38_09615	COG1454	alcohol dehydrogenase
J4N38_09615	COG1012	belongs to the aldehyde dehydrogenase family
J4N38_09620	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J4N38_09655	COG1882	Formate acetyltransferase
J4N38_09670	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J4N38_09680	COG3013	Belongs to the UPF0304 family
J4N38_09685	COG2766	serine protein kinase
J4N38_09690	COG2718	Belongs to the UPF0229 family
J4N38_09695	COG2719	SpoVR family
J4N38_09700	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J4N38_09705	COG2835	tetraacyldisaccharide 4'-kinase activity
J4N38_09715	COG1132	(ABC) transporter
J4N38_09720	COG2333	competence protein COMEC
J4N38_09720	COG0658	competence protein
J4N38_09730	COG4591	ABC-type transport system involved in lipoprotein release permease component
J4N38_09735	COG1136	(ABC) transporter
J4N38_09740	COG4591	ABC-type transport system involved in lipoprotein release permease component
J4N38_09750	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J4N38_09765	COG1252	NADH dehydrogenase
J4N38_09770	COG3150	esterase
J4N38_09795	COG0537	adenosine 5'-monophosphoramidase activity
J4N38_09810	COG2186	Transcriptional regulator
J4N38_09815	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J4N38_09825	COG1674	ftsk spoiiie
J4N38_09835	COG0686	Belongs to the AlaDH PNT family
J4N38_09840	COG3092	negative regulation of chromosome organization
J4N38_09845	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J4N38_09850	COG0857	belongs to the CobB CobQ family
J4N38_09850	COG0280	phosphate acetyltransferase
J4N38_09855	COG0435	Glutathione S-transferase
J4N38_09865	COG0444	Belongs to the ABC transporter superfamily
J4N38_09870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N38_09875	COG0601	transmembrane transport
J4N38_09890	COG2067	long-chain fatty acid transport protein
J4N38_09900	COG0840	transmembrane signaling receptor activity
J4N38_09910	COG1404	Belongs to the peptidase S8 family
J4N38_09915	COG0840	transmembrane signaling receptor activity
J4N38_09940	COG0577	efflux transmembrane transporter activity
J4N38_09940	COG1136	(ABC) transporter
J4N38_09950	COG0577	efflux transmembrane transporter activity
J4N38_09960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N38_09975	COG1770	oligopeptidase
J4N38_10065	COG3706	GGDEF domain
J4N38_10080	COG3126	Type III secretion system lipoprotein chaperone (YscW)
J4N38_10085	COG1946	Acyl-CoA thioesterase
J4N38_10090	COG1522	sequence-specific DNA binding
J4N38_10115	COG0477	Major facilitator Superfamily
J4N38_10120	COG2855	membrane
J4N38_10150	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
J4N38_10155	COG1169	isochorismate synthase
J4N38_10160	COG0436	Aminotransferase
J4N38_10165	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
J4N38_10170	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J4N38_10175	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J4N38_10190	COG0513	Belongs to the DEAD box helicase family
J4N38_10200	COG0616	signal peptide processing
J4N38_10205	COG1028	Short-chain dehydrogenase reductase Sdr
J4N38_10210	COG0469	pyruvate kinase activity
J4N38_10215	COG1940	carbohydrate kinase activity
J4N38_10220	COG0784	Response regulator, receiver
J4N38_10220	COG0835	chemotaxis
J4N38_10235	COG0243	molybdopterin cofactor binding
J4N38_10240	COG3005	denitrification pathway
J4N38_10245	COG4459	periplasmic nitrate reductase
J4N38_10250	COG0390	transport system, permease component
J4N38_10260	COG2116	formate transmembrane transporter activity
J4N38_10285	COG0542	response to heat
J4N38_10295	COG1278	Cold shock
J4N38_10305	COG1187	pseudouridine synthase activity
J4N38_10315	COG1801	Protein of unknown function DUF72
J4N38_10325	COG0500	methyltransferase
J4N38_10330	COG0189	ligase activity
J4N38_10330	COG4067	protein conserved in archaea
J4N38_10345	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J4N38_10350	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
J4N38_10360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4N38_10365	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J4N38_10370	COG0745	RESPONSE REGULATOR receiver
J4N38_10385	COG3070	regulator of competence-specific genes
J4N38_10390	COG3385	transposase activity
J4N38_10410	COG0297	glycogen (starch) synthase activity
J4N38_10415	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J4N38_10420	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4N38_10440	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J4N38_10445	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
J4N38_10450	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J4N38_10455	COG1435	thymidine kinase activity
J4N38_10460	COG0215	cysteine-tRNA ligase activity
J4N38_10465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J4N38_10470	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4N38_10475	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J4N38_10480	COG3012	SEC-C Motif Domain Protein
J4N38_10485	COG3139	Protein of unknown function (DUF1315)
J4N38_10495	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N38_10510	COG2226	methyltransferase
J4N38_10525	COG1785	Belongs to the alkaline phosphatase family
J4N38_10530	COG2771	luxR family
J4N38_10540	COG2814	Major facilitator Superfamily
J4N38_10545	COG1028	Short-chain dehydrogenase reductase Sdr
J4N38_10570	COG2951	lytic endotransglycosylase activity
J4N38_10575	COG3100	YcgL domain-containing protein
J4N38_10580	COG0850	regulation of cytokinetic process
J4N38_10585	COG2894	cell division
J4N38_10590	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
J4N38_10595	COG1454	alcohol dehydrogenase
J4N38_10595	COG1012	belongs to the aldehyde dehydrogenase family
J4N38_10600	COG2095	MarC family integral membrane protein
J4N38_10605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N38_10610	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J4N38_10615	COG1757	Na H antiporter
J4N38_10620	COG2188	Transcriptional regulator
J4N38_10625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N38_10625	COG1263	PTS System
J4N38_10630	COG1621	beta-fructofuranosidase activity
J4N38_10640	COG3081	Nucleoid-associated protein
J4N38_10645	COG3082	Protein of unknown function (DUF1414)
J4N38_10650	COG3083	sulfuric ester hydrolase activity
J4N38_10675	COG0123	including yeast histone deacetylase and acetoin utilization protein
J4N38_10685	COG1881	PFAM PEBP family protein
J4N38_10695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4N38_10700	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J4N38_10720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J4N38_10725	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
J4N38_10765	COG0383	alpha-mannosidase activity
J4N38_10785	COG1940	carbohydrate kinase activity
J4N38_10790	COG2982	Protein involved in outer membrane biogenesis
J4N38_10795	COG0572	uridine kinase
J4N38_10800	COG0489	protein tyrosine kinase activity
J4N38_10805	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4N38_10805	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4N38_10835	COG0517	IMP dehydrogenase activity
J4N38_10835	COG0617	tRNA 3'-terminal CCA addition
J4N38_10835	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J4N38_10845	COG3706	GGDEF domain
J4N38_10850	COG0314	molybdopterin synthase activity
J4N38_10855	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J4N38_10860	COG0315	cyclic pyranopterin monophosphate synthase activity
J4N38_10865	COG0521	Mo-molybdopterin cofactor biosynthetic process
J4N38_10870	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J4N38_10875	COG0391	Required for morphogenesis under gluconeogenic growth conditions
J4N38_10880	COG2198	Histidine kinase
J4N38_10890	COG0556	nucleotide-excision repair
J4N38_10920	COG0739	heme binding
J4N38_10985	COG1987	bacterial-type flagellum assembly
J4N38_11010	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N38_11015	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J4N38_11020	COG1516	flagellar protein fliS
J4N38_11035	COG1580	Controls the rotational direction of flagella during chemotaxis
J4N38_11040	COG1191	sigma factor activity
J4N38_11045	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J4N38_11050	COG1360	Flagellar Motor Protein
J4N38_11080	COG1706	bacterial-type flagellum-dependent cell motility
J4N38_11085	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J4N38_11090	COG4786	Flagellar basal body rod
J4N38_11095	COG4787	bacterial-type flagellum-dependent cell motility
J4N38_11100	COG1749	Flagellar hook protein flgE
J4N38_11105	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
J4N38_11110	COG1558	bacterial-type flagellum-dependent cell motility
J4N38_11115	COG1815	bacterial-type flagellum-dependent cell motility
J4N38_11135	COG0741	lytic transglycosylase activity
J4N38_11135	COG1388	LysM domain
J4N38_11140	COG4657	Part of a membrane complex involved in electron transport
J4N38_11150	COG4656	Part of a membrane complex involved in electron transport
J4N38_11155	COG4658	electron transport chain
J4N38_11160	COG4659	FMN binding
J4N38_11165	COG4660	Part of a membrane complex involved in electron transport
J4N38_11170	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J4N38_11175	COG0346	lactoylglutathione lyase activity
J4N38_11195	COG2056	Na+-H+ antiporter family
J4N38_11200	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
J4N38_11210	COG2716	regulation of RNA biosynthetic process
J4N38_11215	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J4N38_11235	COG4783	chaperone-mediated protein folding
J4N38_11240	COG1393	Belongs to the ArsC family
J4N38_11260	COG2233	PERMEase
J4N38_11265	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J4N38_11275	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J4N38_11280	COG2912	Transglutaminase-like superfamily
J4N38_11290	COG2890	protein-(glutamine-N5) methyltransferase activity
J4N38_11295	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J4N38_11310	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J4N38_11315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J4N38_11440	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N38_11450	COG3951	Flagellar rod assembly protein muramidase FlgJ
J4N38_11450	COG1705	Flagellar rod assembly protein muramidase FlgJ
J4N38_11455	COG1706	bacterial-type flagellum-dependent cell motility
J4N38_11460	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J4N38_11470	COG4787	bacterial-type flagellum-dependent cell motility
J4N38_11490	COG1815	bacterial-type flagellum-dependent cell motility
J4N38_11495	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J4N38_11500	COG0784	Response regulator, receiver
J4N38_11500	COG0835	chemotaxis
J4N38_11510	COG2747	anti-sigma28 factor FlgM
J4N38_11540	COG0500	methyltransferase
J4N38_11565	COG2217	Heavy metal translocating P-type atpase
J4N38_11565	COG2608	mercury ion transmembrane transporter activity
J4N38_11575	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
J4N38_11590	COG0583	DNA-binding transcription factor activity
J4N38_11595	COG0301	tRNA thio-modification
J4N38_11595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4N38_11605	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J4N38_11610	COG1722	exodeoxyribonuclease VII activity
J4N38_11615	COG0142	geranyltranstransferase activity
J4N38_11625	COG0564	pseudouridine synthase activity
J4N38_11630	COG3098	single-species biofilm formation
J4N38_11645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N38_11665	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4N38_11670	COG0567	Dehydrogenase, E1 component
J4N38_11680	COG1053	succinate dehydrogenase
J4N38_11685	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
J4N38_11700	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J4N38_11710	COG0033	Phosphoglucomutase
J4N38_11715	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
J4N38_11720	COG0596	Alpha beta hydrolase
J4N38_11730	COG0716	FMN binding
J4N38_11735	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J4N38_11740	COG3115	cell septum assembly
J4N38_11745	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
J4N38_11750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J4N38_11755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N38_11760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J4N38_11765	COG2190	(PTS) system
J4N38_11770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N38_11775	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J4N38_11780	COG1702	phosphate starvation-inducible protein PhoH
J4N38_11785	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J4N38_11790	COG4535	Mg2 and Co2 transporter CorC
J4N38_11795	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J4N38_11800	COG2888	peptidyl-tyrosine sulfation
J4N38_11805	COG0495	leucyl-tRNA aminoacylation
J4N38_11810	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
J4N38_11815	COG1466	dna polymerase III delta subunit
J4N38_11820	COG0799	negative regulation of ribosome biogenesis
J4N38_11825	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J4N38_11830	COG0768	penicillin binding
J4N38_11835	COG0772	Belongs to the SEDS family
J4N38_11840	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J4N38_11845	COG1686	Belongs to the peptidase S11 family
J4N38_11850	COG2921	Belongs to the UPF0250 family
J4N38_11860	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J4N38_11875	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J4N38_11885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N38_11890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N38_11915	COG0366	Alpha amylase catalytic
J4N38_11920	COG1263	PTS System
J4N38_11920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N38_11925	COG1609	Transcriptional regulator
J4N38_11935	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J4N38_11940	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J4N38_11945	COG2011	ABC-type metal ion transport system permease component
J4N38_11950	COG1464	Belongs to the NlpA lipoprotein family
J4N38_11955	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J4N38_11965	COG0254	rRNA binding
J4N38_11970	COG1720	tRNA m6t6A37 methyltransferase activity
J4N38_11980	COG0121	glutamine amidotransferase
J4N38_11985	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J4N38_11990	COG1960	acyl-CoA dehydrogenase activity
J4N38_12005	COG0328	RNA-DNA hybrid ribonuclease activity
J4N38_12010	COG2226	methyltransferase
J4N38_12015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4N38_12020	COG1388	LysM domain
J4N38_12020	COG0741	lytic transglycosylase activity
J4N38_12030	COG3021	interspecies interaction between organisms
J4N38_12035	COG0347	Belongs to the P(II) protein family
J4N38_12050	COG0825	malonyl-CoA metabolic process
J4N38_12055	COG0587	DNA-directed DNA polymerase activity
J4N38_12060	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J4N38_12065	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4N38_12075	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J4N38_12080	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4N38_12085	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
J4N38_12090	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N38_12095	COG0750	zinc metalloprotease
J4N38_12105	COG0575	Belongs to the CDS family
J4N38_12110	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J4N38_12115	COG0233	cytoplasmic translational termination
J4N38_12120	COG0528	UMP kinase activity
J4N38_12130	COG0052	Belongs to the universal ribosomal protein uS2 family
J4N38_12135	COG0024	Methionine aminopeptidase
J4N38_12140	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
J4N38_12150	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J4N38_12155	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J4N38_12160	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J4N38_12180	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4N38_12180	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4N38_12185	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J4N38_12190	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J4N38_12195	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J4N38_12205	COG1073	alpha beta
J4N38_12210	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
J4N38_12215	COG2252	PERMEase
J4N38_12220	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4N38_12225	COG0189	ligase activity
J4N38_12225	COG4067	protein conserved in archaea
J4N38_12230	COG0189	ligase activity
J4N38_12240	COG0733	neurotransmitter:sodium symporter activity
J4N38_12255	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4N38_12260	COG0514	ATP-dependent DNA helicase (RecQ)
J4N38_12265	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J4N38_12280	COG1477	protein flavinylation
J4N38_12285	COG2871	sodium ion transport
J4N38_12290	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J4N38_12295	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J4N38_12305	COG1805	sodium ion transport
J4N38_12310	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J4N38_12315	COG0271	Belongs to the BolA IbaG family
J4N38_12320	COG2813	Specifically methylates the guanine in position
J4N38_12350	COG1595	DNA-templated transcription, initiation
J4N38_12365	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J4N38_12370	COG0693	protein deglycase activity
J4N38_12375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J4N38_12380	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J4N38_12390	COG0560	Phosphoserine phosphatase
J4N38_12400	COG0813	purine-nucleoside phosphorylase activity
J4N38_12405	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
J4N38_12410	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
J4N38_12425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4N38_12430	COG0084	hydrolase, TatD family'
J4N38_12440	COG3022	response to hydroperoxide
J4N38_12445	COG1115	amino acid carrier protein
J4N38_12460	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J4N38_12470	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
J4N38_12475	COG0583	DNA-binding transcription factor activity
J4N38_12480	COG0730	response to heat
J4N38_12485	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J4N38_12490	COG0505	Belongs to the CarA family
J4N38_12500	COG0494	nUDIX hydrolase
J4N38_12505	COG0653	protein targeting
J4N38_12510	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J4N38_12515	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J4N38_12520	COG0849	cell division
J4N38_12525	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J4N38_12540	COG0772	Belongs to the SEDS family
J4N38_12545	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J4N38_12555	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J4N38_12560	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J4N38_12565	COG0768	penicillin binding
J4N38_12570	COG3116	cell division
J4N38_12585	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J4N38_12590	COG3107	peptidoglycan biosynthetic process
J4N38_12595	COG0792	nuclease activity
J4N38_12600	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J4N38_12610	COG2969	positive regulation of protein catabolic process
J4N38_12615	COG0625	glutathione transferase activity
J4N38_12620	COG2857	Cytochrome c1
J4N38_12625	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J4N38_12630	COG0723	plastoquinol--plastocyanin reductase activity
J4N38_12645	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J4N38_12650	COG3105	Protein conserved in bacteria
J4N38_12655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4N38_12660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4N38_12675	COG3150	esterase
J4N38_12685	COG3151	Protein conserved in bacteria
J4N38_12690	COG0494	nUDIX hydrolase
J4N38_12695	COG1538	Outer membrane efflux protein
J4N38_12705	COG0784	Response regulator, receiver
J4N38_12705	COG2198	Histidine kinase
J4N38_12705	COG5002	protein histidine kinase activity
J4N38_12710	COG5001	Diguanylate cyclase
J4N38_12710	COG4251	negative regulation of phosphorylation
J4N38_12710	COG3706	GGDEF domain
J4N38_12710	COG2203	Gaf domain
J4N38_12715	COG1242	4 iron, 4 sulfur cluster binding
J4N38_12720	COG0069	glutamate synthase activity
J4N38_12720	COG0070	glutamate synthase
J4N38_12720	COG0067	glutamate synthase
J4N38_12730	COG0067	glutamate synthase
J4N38_12730	COG0069	glutamate synthase activity
J4N38_12730	COG0070	glutamate synthase
J4N38_12735	COG0493	'glutamate synthase
J4N38_12760	COG0195	Participates in both transcription termination and antitermination
J4N38_12765	COG0779	Required for maturation of 30S ribosomal subunits
J4N38_12840	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J4N38_12845	COG3153	acetyltransferase
J4N38_12850	COG3154	lipid carrier protein
J4N38_12860	COG0826	peptidase U32
J4N38_12865	COG0826	peptidase U32
J4N38_12870	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J4N38_12890	COG0513	Belongs to the DEAD box helicase family
J4N38_12905	COG0456	acetyltransferase
J4N38_12915	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4N38_12920	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J4N38_12925	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J4N38_12930	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
J4N38_12935	COG1534	Rna-binding protein
J4N38_12940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4N38_12945	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J4N38_12960	COG0316	Belongs to the HesB IscA family
J4N38_12970	COG0628	permease
J4N38_12975	COG2813	Specifically methylates the guanine in position
J4N38_12980	COG2205	protein histidine kinase activity
J4N38_12980	COG0784	Response regulator, receiver
J4N38_12980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N38_12980	COG2198	Histidine kinase
J4N38_12985	COG0747	negative chemotaxis
J4N38_13000	COG0444	Belongs to the ABC transporter superfamily
J4N38_13005	COG4608	Belongs to the ABC transporter superfamily
J4N38_13015	COG2971	BadF BadG BcrA BcrD
J4N38_13030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4N38_13035	COG3842	ATPase activity
J4N38_13045	COG1840	ABC-type Fe3 transport system, periplasmic component
J4N38_13050	COG0004	ammonium transporteR
J4N38_13060	COG3112	Uncharacterised protein family (UPF0231)
J4N38_13065	COG1049	propionate catabolic process, 2-methylcitrate cycle
J4N38_13070	COG1752	Esterase of the alpha-beta hydrolase superfamily
J4N38_13075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4N38_13150	COG3119	arylsulfatase activity
J4N38_13155	COG1309	transcriptional regulator
J4N38_13185	COG1643	Atp-dependent helicase
J4N38_13195	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J4N38_13210	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J4N38_13215	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J4N38_13225	COG0842	Transport permease protein
J4N38_13230	COG1131	(ABC) transporter
J4N38_13235	COG0659	secondary active sulfate transmembrane transporter activity
J4N38_13240	COG0288	reversible hydration of carbon dioxide
J4N38_13255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N38_13260	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4N38_13265	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
J4N38_13270	COG2186	Transcriptional regulator
J4N38_13275	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J4N38_13280	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4N38_13285	COG4974	Belongs to the 'phage' integrase family
J4N38_13290	COG0716	FMN binding
J4N38_13300	COG0157	Belongs to the NadC ModD family
J4N38_13305	COG4969	Belongs to the N-Me-Phe pilin family
J4N38_13310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4N38_13315	COG1459	type II secretion system
J4N38_13325	COG0237	dephospho-CoA kinase activity
J4N38_13330	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
J4N38_13335	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
J4N38_13345	COG0336	Belongs to the RNA methyltransferase TrmD family
J4N38_13355	COG0228	four-way junction DNA binding
J4N38_13360	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J4N38_13365	COG4137	Cytochrome C assembly protein
J4N38_13370	COG4536	flavin adenine dinucleotide binding
J4N38_13375	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J4N38_13380	COG1388	LysM domain
J4N38_13380	COG4942	peptidase
J4N38_13390	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J4N38_13395	COG0585	pseudouridine synthase activity
J4N38_13400	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J4N38_13405	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J4N38_13410	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J4N38_13415	COG1968	undecaprenyl-diphosphatase activity
J4N38_13420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J4N38_13425	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J4N38_13430	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J4N38_13435	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J4N38_13440	COG3385	transposase activity
J4N38_13445	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J4N38_13450	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J4N38_13455	COG1610	YqeY-like protein
J4N38_13460	COG0358	DNA primase activity
J4N38_13475	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
J4N38_13480	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
J4N38_13485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4N38_13490	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J4N38_13495	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J4N38_13505	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J4N38_13510	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J4N38_13515	COG3610	response to peptide
J4N38_13520	COG2966	Psort location CytoplasmicMembrane, score
J4N38_13525	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J4N38_13535	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J4N38_13540	COG0142	geranyltranstransferase activity
J4N38_13590	COG3437	response regulator, receiver
J4N38_13605	COG0270	DNA (cytosine-5-)-methyltransferase activity
J4N38_13640	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J4N38_13705	COG1854	S-ribosylhomocysteine lyase activity
J4N38_13720	COG0612	Peptidase, M16
J4N38_13725	COG1238	metal cluster binding
J4N38_13735	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
J4N38_13740	COG5016	pyruvate
J4N38_13740	COG0511	ligase activity, forming carbon-carbon bonds
J4N38_13745	COG3630	sodium ion export across plasma membrane
J4N38_13810	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J4N38_13815	COG1546	Belongs to the CinA family
J4N38_13820	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J4N38_13825	COG0795	lipopolysaccharide-transporting ATPase activity
J4N38_13830	COG0795	lipopolysaccharide-transporting ATPase activity
J4N38_13840	COG2927	DNA polymerase III (CHI subunit)
J4N38_13845	COG0525	valine-tRNA ligase activity
J4N38_13855	COG4269	membrane
J4N38_13865	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J4N38_13870	COG0564	pseudouridine synthase activity
J4N38_13885	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J4N38_13900	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
J4N38_13905	COG0251	oxidation-reduction process
J4N38_13915	COG0039	L-malate dehydrogenase activity
J4N38_13920	COG1438	arginine binding
J4N38_13925	COG2358	TRAP transporter, solute receptor (TAXI family
J4N38_13935	COG0589	response to stress
J4N38_13960	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J4N38_13965	COG0527	aspartate kinase activity
J4N38_13970	COG0312	modulator of DNA gyrase
J4N38_13975	COG3028	Belongs to the UPF0307 family
J4N38_13980	COG0204	Acyl-transferase
J4N38_13985	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J4N38_13990	COG5007	Belongs to the BolA IbaG family
J4N38_14000	COG2854	intermembrane phospholipid transfer
J4N38_14005	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J4N38_14010	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J4N38_14015	COG1127	ABC transporter
J4N38_14025	COG0517	IMP dehydrogenase activity
J4N38_14025	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J4N38_14030	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
J4N38_14040	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J4N38_14045	COG1137	ATPase activity
J4N38_14055	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J4N38_14060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N38_14065	COG1660	Displays ATPase and GTPase activities
J4N38_14070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N38_14075	COG2239	Acts as a magnesium transporter
J4N38_14080	COG0646	methionine synthase
J4N38_14080	COG1410	methionine synthase
J4N38_14150	COG0175	sulfate reduction
J4N38_14155	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4N38_14160	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J4N38_14185	COG3437	response regulator, receiver
J4N38_14190	COG0784	Response regulator, receiver
J4N38_14190	COG2205	protein histidine kinase activity
J4N38_14190	COG5002	protein histidine kinase activity
J4N38_14195	COG0735	belongs to the Fur family
J4N38_14205	COG0529	Catalyzes the synthesis of activated sulfate
J4N38_14210	COG3273	potassium ion transport
J4N38_14210	COG0471	metal ion transport
J4N38_14225	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J4N38_14225	COG1648	precorrin-2 dehydrogenase activity
J4N38_14230	COG0737	Belongs to the 5'-nucleotidase family
J4N38_14240	COG2153	protein acetylation
J4N38_14255	COG0545	Peptidyl-prolyl cis-trans isomerase
J4N38_14265	COG0203	ribosomal protein L17
J4N38_14270	COG0202	RNA polymerase activity
J4N38_14280	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J4N38_14285	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J4N38_14290	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J4N38_14295	COG0201	protein transport
J4N38_14300	COG0200	Binds to the 23S rRNA
J4N38_14305	COG1841	ribosomal large subunit assembly
J4N38_14320	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J4N38_14325	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J4N38_14335	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J4N38_14350	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J4N38_14365	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J4N38_14370	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J4N38_14375	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J4N38_14390	COG0088	Forms part of the polypeptide exit tunnel
J4N38_14395	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J4N38_14400	COG0051	transcription antitermination factor activity, RNA binding
J4N38_14405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4N38_14410	COG0557	exoribonuclease II activity
J4N38_14415	COG0402	S-adenosylhomocysteine deaminase activity
J4N38_14420	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
J4N38_14425	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J4N38_14435	COG1047	Peptidyl-prolyl cis-trans
J4N38_14450	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N38_14455	COG0488	(ABC) transporter
J4N38_14465	COG0429	hydrolase of the alpha beta-hydrolase fold
J4N38_14470	COG3089	Belongs to the UPF0270 family
J4N38_14475	COG3954	Phosphoribulokinase
J4N38_14480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N38_14485	COG0490	domain, Protein
J4N38_14485	COG0471	metal ion transport
J4N38_14500	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J4N38_14505	COG4942	peptidase
J4N38_14525	COG2816	NAD+ diphosphatase activity
J4N38_14530	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
J4N38_14535	COG1288	antiporter activity
J4N38_14550	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J4N38_14555	COG0540	Belongs to the ATCase OTCase family
J4N38_14560	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
J4N38_14565	COG1438	arginine binding
J4N38_14570	COG4232	protein-disulfide reductase activity
J4N38_14580	COG2095	MarC family integral membrane protein
J4N38_14590	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N38_14610	COG0149	triose-phosphate isomerase activity
J4N38_14615	COG0534	Mate efflux family protein
J4N38_14620	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J4N38_14625	COG1575	Belongs to the MenA family. Type 1 subfamily
J4N38_14630	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J4N38_14635	COG1509	lysine 2,3-aminomutase activity
J4N38_14645	COG1285	pathogenesis
J4N38_14655	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J4N38_14665	COG0745	RESPONSE REGULATOR receiver
J4N38_14670	COG2205	protein histidine kinase activity
J4N38_14675	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J4N38_14680	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J4N38_14685	COG0180	Tryptophanyl-tRNA synthetase
J4N38_14690	COG0546	phosphoglycolate phosphatase activity
J4N38_14695	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J4N38_14700	COG0338	D12 class N6 adenine-specific DNA methyltransferase
J4N38_14710	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J4N38_14745	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J4N38_14755	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J4N38_14755	COG0678	peroxiredoxin activity
J4N38_14760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N38_14765	COG0251	oxidation-reduction process
J4N38_14775	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J4N38_14775	COG0165	Argininosuccinate lyase
J4N38_14780	COG0137	argininosuccinate synthase activity
J4N38_14785	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J4N38_14790	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J4N38_14860	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J4N38_14870	COG4206	TonB-dependent receptor
J4N38_14890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N38_14895	COG0534	Mate efflux family protein
J4N38_14905	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J4N38_14910	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J4N38_14915	COG2937	Belongs to the GPAT DAPAT family
J4N38_14920	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
J4N38_14925	COG3161	chorismate lyase activity
J4N38_14930	COG1580	Controls the rotational direction of flagella during chemotaxis
J4N38_14935	COG0705	Rhomboid family
J4N38_14940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4N38_14945	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J4N38_14950	COG2177	Part of the ABC transporter FtsEX involved in
J4N38_14955	COG2884	Cell division ATP-binding protein ftsE
J4N38_14960	COG0552	protein localization to endoplasmic reticulum
J4N38_14965	COG0742	ribosomal rna small subunit methyltransferase
J4N38_14975	COG2095	MarC family integral membrane protein
J4N38_15020	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J4N38_15025	COG0640	Transcriptional regulator
J4N38_15030	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J4N38_15035	COG1280	lysine exporter protein (LysE YggA)
J4N38_15040	COG2267	carboxylic ester hydrolase activity
J4N38_15045	COG0561	phosphatase activity
J4N38_15060	COG3148	PFAM DTW domain containing protein
J4N38_15065	COG1011	Hydrolase
J4N38_15080	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J4N38_15085	COG0019	diaminopimelate decarboxylase activity
J4N38_15095	COG1965	Belongs to the frataxin family
J4N38_15100	COG3072	Adenylate cyclase
J4N38_15105	COG0181	hydroxymethylbilane synthase activity
J4N38_15110	COG1587	Uroporphyrinogen-III synthase
J4N38_15115	COG2959	enzyme of heme biosynthesis
J4N38_15120	COG3071	HemY protein
J4N38_15155	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
J4N38_15170	COG3118	belongs to the thioredoxin family
J4N38_15180	COG0248	Ppx GppA phosphatase
J4N38_15185	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J4N38_15195	COG0514	ATP-dependent DNA helicase (RecQ)
J4N38_15200	COG2962	Rard protein
J4N38_15210	COG1280	lysine exporter protein (LysE YggA)
J4N38_15215	COG0405	Gamma-glutamyltransferase
J4N38_15220	COG0210	DNA helicase
J4N38_15230	COG3220	belongs to the UPF0276 family
J4N38_15250	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J4N38_15255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N38_15270	COG0644	oxidoreductase
J4N38_15280	COG3527	Alpha-acetolactate decarboxylase
J4N38_15295	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_15300	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_15310	COG2207	Transcriptional regulator
J4N38_15315	COG3537	Alpha-1,2-mannosidase
J4N38_15325	COG3537	Alpha-1,2-mannosidase
J4N38_15330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_15335	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N38_15335	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_15335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_15355	COG0477	Major facilitator Superfamily
J4N38_15375	COG2197	response regulator
J4N38_15390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N38_15395	COG0601	transmembrane transport
J4N38_15440	COG0210	DNA helicase
J4N38_15445	COG1309	transcriptional regulator
J4N38_15450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N38_15455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N38_15460	COG2960	long-chain fatty acid transporting porin activity
J4N38_15465	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J4N38_15470	COG0583	DNA-binding transcription factor activity
J4N38_15475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J4N38_15505	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4N38_15505	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4N38_15520	COG0084	hydrolase, TatD family'
J4N38_15525	COG0805	protein transport
J4N38_15530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J4N38_15535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J4N38_15540	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J4N38_15550	COG2226	methyltransferase
J4N38_15555	COG1322	Protein conserved in bacteria
J4N38_15565	COG1639	'signal transduction protein
J4N38_15585	COG2081	HI0933 family
J4N38_15595	COG1528	Iron-storage protein
J4N38_15600	COG0589	response to stress
J4N38_15615	COG0742	ribosomal rna small subunit methyltransferase
J4N38_15620	COG5001	Diguanylate cyclase
J4N38_15620	COG5002	protein histidine kinase activity
J4N38_15625	COG1522	sequence-specific DNA binding
J4N38_15645	COG0006	proline dipeptidase activity
J4N38_15645	COG0006	proline dipeptidase activity
J4N38_15655	COG2022	thiamine diphosphate biosynthetic process
J4N38_15665	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J4N38_15670	COG0352	thiamine-phosphate diphosphorylase activity
J4N38_15685	COG2132	Multicopper oxidase
J4N38_15730	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4N38_15735	COG1739	Uncharacterized protein family UPF0029
J4N38_15745	COG0183	Belongs to the thiolase family
J4N38_15750	COG0583	DNA-binding transcription factor activity
J4N38_15755	COG2814	Major facilitator Superfamily
J4N38_15765	COG0765	amino acid transport
J4N38_15775	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J4N38_15780	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J4N38_15785	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J4N38_15790	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J4N38_15795	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J4N38_15800	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J4N38_15815	COG3312	ion transport
J4N38_15820	COG1475	DNA binding
J4N38_15825	COG1192	Involved in chromosome partitioning
J4N38_15830	COG0357	Ribosomal RNA small subunit methyltransferase G
J4N38_15835	COG0445	tRNA wobble uridine modification
J4N38_15840	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J4N38_15850	COG0706	membrane insertase activity
J4N38_15865	COG0230	Belongs to the bacterial ribosomal protein bL34 family
J4N38_15870	COG1126	abc transporter atp-binding protein
J4N38_15895	COG1444	tRNA N-acetyltransferase activity
J4N38_15910	COG0643	Histidine kinase
J4N38_15910	COG2198	Histidine kinase
J4N38_15920	COG0835	chemotaxis
J4N38_15925	COG0840	transmembrane signaling receptor activity
J4N38_15930	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J4N38_15980	COG0583	DNA-binding transcription factor activity
J4N38_15985	COG1175	transmembrane transport
J4N38_16005	COG0546	phosphoglycolate phosphatase activity
J4N38_16010	COG3842	ATPase activity
J4N38_16015	COG0589	response to stress
J4N38_16020	COG2723	6-phospho-beta-galactosidase activity
J4N38_16050	COG0583	DNA-binding transcription factor activity
J4N38_16065	COG0351	phosphomethylpyrimidine kinase
J4N38_16070	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J4N38_16085	COG4977	sequence-specific DNA binding
J4N38_16100	COG0671	phosphoesterase, PA-phosphatase related
J4N38_16145	COG0697	spore germination
J4N38_16180	COG0471	metal ion transport
J4N38_16190	COG2814	Major facilitator Superfamily
J4N38_16195	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J4N38_16235	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
J4N38_16250	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
J4N38_16260	COG2207	Transcriptional regulator
J4N38_16275	COG4999	Histidine kinase
J4N38_16275	COG3850	Histidine kinase
J4N38_16275	COG3437	response regulator, receiver
J4N38_16275	COG2205	protein histidine kinase activity
J4N38_16280	COG0402	S-adenosylhomocysteine deaminase activity
J4N38_16290	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J4N38_16300	COG2186	Transcriptional regulator
J4N38_16310	COG0402	S-adenosylhomocysteine deaminase activity
J4N38_16315	COG1404	Belongs to the peptidase S8 family
J4N38_16345	COG0456	acetyltransferase
J4N38_16360	COG2909	trisaccharide binding
J4N38_16365	COG0058	SHG alpha-glucan phosphorylase activity
J4N38_16370	COG1640	4-alpha-glucanotransferase
J4N38_16375	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J4N38_16395	COG1472	Belongs to the glycosyl hydrolase 3 family
J4N38_16400	COG3876	Protein conserved in bacteria
J4N38_16415	COG3293	Transposase
J4N38_16465	COG0561	phosphatase activity
J4N38_16485	COG0488	(ABC) transporter
J4N38_16510	COG1733	regulation of RNA biosynthetic process
J4N38_16515	COG0456	acetyltransferase
J4N38_16520	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J4N38_16525	COG0662	Cupin 2, conserved barrel domain protein
J4N38_16530	COG0527	aspartate kinase activity
J4N38_16550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_16550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_16550	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
J4N38_16555	COG0383	alpha-mannosidase activity
J4N38_16565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_16565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N38_16565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_16590	COG0113	porphobilinogen synthase activity
J4N38_16595	COG0183	Belongs to the thiolase family
J4N38_16605	COG3246	L-lysine catabolic process to acetate
J4N38_16635	COG0583	DNA-binding transcription factor activity
J4N38_16640	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J4N38_16650	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N38_16655	COG4999	Histidine kinase
J4N38_16655	COG3437	response regulator, receiver
J4N38_16655	COG2205	protein histidine kinase activity
J4N38_16655	COG3850	Histidine kinase
J4N38_16665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J4N38_16695	COG0657	acetylesterase activity
J4N38_16705	COG3448	diguanylate cyclase activity
J4N38_16705	COG4175	Glycine betaine
J4N38_16710	COG4176	ABC-type proline glycine betaine transport system permease component
J4N38_16730	COG2095	MarC family integral membrane protein
J4N38_16740	COG0583	DNA-binding transcription factor activity
J4N38_16765	COG4964	Belongs to the GSP D family
J4N38_16775	COG2894	cell division
J4N38_16830	COG1477	protein flavinylation
J4N38_16845	COG0840	transmembrane signaling receptor activity
J4N38_16855	COG0573	inorganic phosphate transmembrane transporter activity
J4N38_16860	COG0581	inorganic phosphate transmembrane transporter activity
J4N38_16865	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4N38_16880	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
J4N38_16885	COG1162	GTPase activity
J4N38_16895	COG0363	glucosamine-6-phosphate deaminase activity
J4N38_16915	COG0454	-acetyltransferase
J4N38_16940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N38_16950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4N38_16955	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J4N38_16960	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
J4N38_16975	COG3655	Transcriptional regulator
J4N38_16985	COG0137	argininosuccinate synthase activity
J4N38_17000	COG3608	succinylglutamate desuccinylase aspartoacylase
J4N38_17020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N38_17030	COG3314	Sporulation integral membrane protein YlbJ
J4N38_17035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4N38_17040	COG1151	hydroxylamine reductase activity
J4N38_17050	COG0583	DNA-binding transcription factor activity
J4N38_17065	COG3604	Transcriptional regulator
J4N38_17095	COG3046	protein related to deoxyribodipyrimidine photolyase
J4N38_17105	COG2329	Antibiotic biosynthesis monooxygenase
J4N38_17110	COG3304	Inner membrane component domain
J4N38_17120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N38_17175	COG0004	ammonium transporteR
J4N38_17185	COG3383	formate dehydrogenase (NAD+) activity
J4N38_17195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4N38_17215	COG0739	heme binding
J4N38_17220	COG3047	cAMP biosynthetic process
J4N38_17260	COG2271	Major facilitator Superfamily
J4N38_17265	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N38_17285	COG0431	NADPH-dependent FMN reductase
J4N38_17290	COG0697	spore germination
J4N38_17315	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J4N38_17315	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J4N38_17320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4N38_17320	COG2207	Transcriptional regulator
J4N38_17325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N38_17330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N38_17340	COG1522	sequence-specific DNA binding
J4N38_17350	COG0840	transmembrane signaling receptor activity
J4N38_17360	COG1357	PFAM Pentapeptide repeats (8 copies)
J4N38_17380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4N38_17395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N38_17405	COG1309	transcriptional regulator
J4N38_17420	COG0745	RESPONSE REGULATOR receiver
J4N38_17425	COG5002	protein histidine kinase activity
J4N38_17485	COG1054	Belongs to the UPF0176 family
J4N38_17500	COG1028	Short-chain dehydrogenase reductase Sdr
J4N38_17525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N38_17535	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J4N38_17555	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J4N38_17565	COG1733	regulation of RNA biosynthetic process
J4N38_17580	COG3795	YCII-related domain
J4N38_17585	COG4941	Belongs to the sigma-70 factor family
J4N38_17590	COG0625	glutathione transferase activity
J4N38_17595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N38_17600	COG0366	Alpha amylase catalytic
J4N38_17620	COG2084	Dehydrogenase
J4N38_17635	COG2130	NADP-dependent
J4N38_17640	COG1309	transcriptional regulator
J4N38_17655	COG3097	Belongs to the UPF0267 family
J4N38_17660	COG0513	Belongs to the DEAD box helicase family
J4N38_17670	COG1228	amidohydrolase
J4N38_17695	COG1175	transmembrane transport
J4N38_17700	COG0395	ABC-type sugar transport system, permease component
J4N38_17705	COG1554	hydrolase, family 65, central catalytic
J4N38_17710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N38_17715	COG3842	ATPase activity
J4N38_17725	COG1621	beta-fructofuranosidase activity
J4N38_17735	COG1609	Transcriptional regulator
J4N38_17760	COG3842	ATPase activity
J4N38_17765	COG1472	Belongs to the glycosyl hydrolase 3 family
J4N38_17780	COG0110	maltose O-acetyltransferase activity
J4N38_17805	COG2356	endonuclease I
J4N38_17820	COG0564	pseudouridine synthase activity
J4N38_17840	COG0583	DNA-binding transcription factor activity
J4N38_17845	COG2814	Major facilitator Superfamily
J4N38_17870	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J4N38_17880	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J4N38_17885	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J4N38_17890	COG0579	oxidoreductase
J4N38_17910	COG1012	belongs to the aldehyde dehydrogenase family
J4N38_17915	COG3284	Transcriptional regulator
J4N38_17940	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J4N38_17945	COG0363	glucosamine-6-phosphate deaminase activity
J4N38_17950	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J4N38_17955	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J4N38_17965	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J4N38_17975	COG2271	Major facilitator Superfamily
J4N38_17980	COG3851	Histidine kinase
J4N38_17985	COG2197	response regulator
J4N38_18005	COG0418	dihydroorotase activity
J4N38_18010	COG0633	Ferredoxin
J4N38_18010	COG3217	Mosc domain protein beta barrel domain protein
J4N38_18010	COG3217	Mosc domain protein beta barrel domain protein
J4N38_18010	COG0633	Ferredoxin
J4N38_18020	COG1349	DNA-binding transcription factor activity
J4N38_18040	COG2354	Protein conserved in bacteria
J4N38_18050	COG0366	Alpha amylase catalytic
J4N38_18075	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J4N38_18090	COG0739	heme binding
J4N38_18105	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
J4N38_18110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N38_18120	COG0848	biopolymer transport protein
J4N38_18125	COG0811	peptide transport
J4N38_18130	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
J4N38_18140	COG3721	Heme iron utilization protein
J4N38_18145	COG0748	coenzyme F420 binding
J4N38_18150	COG2096	Adenosyltransferase
J4N38_18155	COG3842	ATPase activity
J4N38_18165	COG1175	transmembrane transport
J4N38_18170	COG3833	ABC-type maltose transport systems, permease component
J4N38_18180	COG4533	DNA binding
J4N38_18220	COG0784	Response regulator, receiver
J4N38_18220	COG5002	protein histidine kinase activity
J4N38_18220	COG2205	protein histidine kinase activity
J4N38_18230	COG0861	Integral membrane protein TerC family
J4N38_18235	COG0402	S-adenosylhomocysteine deaminase activity
J4N38_18240	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J4N38_18245	COG1566	PFAM secretion protein HlyD family protein
J4N38_18270	COG0745	RESPONSE REGULATOR receiver
J4N38_18290	COG0121	glutamine amidotransferase
J4N38_18295	COG0531	amino acid
J4N38_18315	COG0673	inositol 2-dehydrogenase activity
J4N38_18320	COG1765	OsmC-like protein
J4N38_18325	COG3385	transposase activity
J4N38_18330	COG0110	maltose O-acetyltransferase activity
J4N38_18355	COG2304	oxidoreductase activity
J4N38_18360	COG2304	oxidoreductase activity
J4N38_18375	COG0714	Associated with various cellular activities
J4N38_18405	COG5002	protein histidine kinase activity
J4N38_18410	COG0745	RESPONSE REGULATOR receiver
J4N38_18420	COG0745	RESPONSE REGULATOR receiver
J4N38_18425	COG2205	protein histidine kinase activity
J4N38_18430	COG4452	Inner membrane protein CreD
J4N38_18435	COG0346	lactoylglutathione lyase activity
J4N38_18445	COG0156	8-amino-7-oxononanoate synthase activity
J4N38_18450	COG1063	alcohol dehydrogenase
J4N38_18465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4N38_18470	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4N38_18495	COG2205	protein histidine kinase activity
J4N38_18495	COG0784	Response regulator, receiver
J4N38_18500	COG2205	protein histidine kinase activity
J4N38_18500	COG0784	Response regulator, receiver
J4N38_18505	COG5002	protein histidine kinase activity
J4N38_18505	COG2205	protein histidine kinase activity
J4N38_18505	COG0784	Response regulator, receiver
J4N38_18520	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4N38_18525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J4N38_18530	COG3186	Phenylalanine-4-hydroxylase
J4N38_18570	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N38_18575	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N38_18600	COG1454	alcohol dehydrogenase
J4N38_18605	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
J4N38_18620	COG1011	Hydrolase
J4N38_18650	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J4N38_18655	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J4N38_18660	COG1840	ABC-type Fe3 transport system, periplasmic component
J4N38_18665	COG3842	ATPase activity
J4N38_18690	COG2866	Carboxypeptidase
J4N38_18695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4N38_18700	COG0583	DNA-binding transcription factor activity
J4N38_18705	COG1760	l-serine dehydratase
J4N38_18725	COG3706	GGDEF domain
J4N38_18730	COG0784	Response regulator, receiver
J4N38_18730	COG0835	chemotaxis
J4N38_18735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4N38_18755	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
J4N38_18760	COG0494	nUDIX hydrolase
J4N38_18765	COG0714	Associated with various cellular activities
J4N38_18770	COG2425	protein containing a von Willebrand factor type A (vWA) domain
J4N38_18790	COG3706	GGDEF domain
J4N38_18795	COG1846	Transcriptional regulator
J4N38_18800	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N38_18825	COG3048	D-serine ammonia-lyase activity
J4N38_18845	COG0814	amino acid
J4N38_18855	COG0513	Belongs to the DEAD box helicase family
J4N38_18860	COG0840	transmembrane signaling receptor activity
J4N38_18865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N38_18870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N38_18885	COG0546	phosphoglycolate phosphatase activity
J4N38_18900	COG0243	molybdopterin cofactor binding
J4N38_18905	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J4N38_18905	COG1648	precorrin-2 dehydrogenase activity
J4N38_18910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J4N38_18920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J4N38_18920	COG1116	anion transmembrane transporter activity
J4N38_18925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J4N38_18930	COG1116	anion transmembrane transporter activity
J4N38_18935	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4N38_18935	COG2146	nitrite reductase [NAD(P)H] activity
J4N38_18940	COG2146	nitrite reductase [NAD(P)H] activity
J4N38_18945	COG1858	cytochrome C peroxidase
J4N38_18970	COG3118	belongs to the thioredoxin family
J4N38_18975	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J4N38_18980	COG0420	3'-5' exonuclease activity
J4N38_18985	COG0419	ATPase involved in DNA repair
J4N38_18990	COG0784	Response regulator, receiver
J4N38_18990	COG2205	protein histidine kinase activity
J4N38_18995	COG0156	8-amino-7-oxononanoate synthase activity
J4N38_19005	COG0038	chloride channel
J4N38_19010	COG0523	cobalamin synthesis protein
J4N38_19015	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J4N38_19040	COG1522	sequence-specific DNA binding
J4N38_19045	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J4N38_19050	COG1072	(Pantothenic acid kinase))
J4N38_19060	COG1063	alcohol dehydrogenase
J4N38_19065	COG2213	PTS system mannitol-specific
J4N38_19070	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N38_19075	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J4N38_19080	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J4N38_19090	COG0583	DNA-binding transcription factor activity
J4N38_19105	COG2897	thiosulfate sulfurtransferase activity
J4N38_19110	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J4N38_19125	COG0513	Belongs to the DEAD box helicase family
J4N38_19130	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N38_19130	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N38_19160	COG3293	Transposase
J4N38_19165	COG0800	Aldolase
J4N38_19170	COG1803	Methylglyoxal synthase
J4N38_19175	COG1879	ABC-type sugar transport system periplasmic component
J4N38_19180	COG2205	protein histidine kinase activity
J4N38_19180	COG2198	Histidine kinase
J4N38_19180	COG0784	Response regulator, receiver
J4N38_19190	COG1979	alcohol dehydrogenase
J4N38_19195	COG2207	Transcriptional regulator
J4N38_19200	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J4N38_19210	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
J4N38_19210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_19210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N38_19215	COG1105	Belongs to the carbohydrate kinase PfkB family
J4N38_19220	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N38_19220	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N38_19225	COG1609	Transcriptional regulator
J4N38_19240	COG1492	cobalamin metabolic process
J4N38_19245	COG0725	ABC transporter, periplasmic molybdate-binding protein
J4N38_19250	COG4149	molybdate abc transporter
J4N38_19255	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
J4N38_19265	COG5001	Diguanylate cyclase
J4N38_19265	COG4251	negative regulation of phosphorylation
J4N38_19265	COG2203	Gaf domain
J4N38_19265	COG3706	GGDEF domain
J4N38_19270	COG3706	GGDEF domain
J4N38_19285	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J4N38_19290	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
J4N38_19300	COG0745	RESPONSE REGULATOR receiver
J4N38_19315	COG3140	Belongs to the UPF0181 family
J4N38_19335	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J4N38_19375	COG0023	Translation Initiation Factor
J4N38_19395	COG3266	domain, Protein
J4N38_19400	COG1042	CoA-binding domain protein
J4N38_19400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N38_19400	COG0045	succinate-CoA ligase (ADP-forming) activity
J4N38_19405	COG0583	DNA-binding transcription factor activity
J4N38_19410	COG4771	TonB-dependent receptor
J4N38_19410	COG1629	transport
J4N38_19415	COG0840	transmembrane signaling receptor activity
J4N38_19435	COG3706	GGDEF domain
J4N38_19455	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
J4N38_19460	COG1028	Short-chain dehydrogenase reductase Sdr
J4N38_19470	COG1024	Enoyl-CoA hydratase
J4N38_19475	COG1024	Enoyl-CoA hydratase
J4N38_19490	COG0183	Belongs to the thiolase family
J4N38_19500	COG1960	acyl-CoA dehydrogenase activity
J4N38_19505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J4N38_19510	COG1024	Enoyl-CoA hydratase
J4N38_19540	COG2259	Doxx family
J4N38_19545	COG1741	Belongs to the pirin family
J4N38_19555	COG1115	amino acid carrier protein
J4N38_19560	COG0583	DNA-binding transcription factor activity
J4N38_19565	COG2910	NAD(P)H-binding
J4N38_19600	COG1132	(ABC) transporter
J4N38_19605	COG1129	ABC transporter
J4N38_19630	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J4N38_19635	COG3300	MHYT domain
J4N38_19635	COG5001	Diguanylate cyclase
J4N38_19640	COG0789	Transcriptional regulator
J4N38_19650	COG2176	DNA-directed DNA polymerase activity
J4N38_19660	COG4533	DNA binding
J4N38_19670	COG2050	protein possibly involved in aromatic compounds catabolism
J4N38_19710	COG0737	Belongs to the 5'-nucleotidase family
J4N38_19715	COG3593	DNA synthesis involved in DNA repair
J4N38_19725	COG0583	DNA-binding transcription factor activity
J4N38_19730	COG2116	formate transmembrane transporter activity
J4N38_19735	COG2353	YceI-like domain
J4N38_19740	COG3038	cytochrome b561
J4N38_19760	COG3069	C4-dicarboxylate transmembrane transporter activity
J4N38_19765	COG2197	response regulator
J4N38_19770	COG3850	Histidine kinase
J4N38_19775	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J4N38_19785	COG0243	molybdopterin cofactor binding
J4N38_19805	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4N38_19810	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
J4N38_19820	COG1984	allophanate hydrolase subunit 2
J4N38_19830	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
J4N38_19835	COG4181	ATPase activity
J4N38_19845	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J4N38_19850	COG1716	ATPase activity
J4N38_19850	COG5001	Diguanylate cyclase
J4N38_19860	COG0484	heat shock protein binding
J4N38_19875	COG1324	tolerance protein
J4N38_19880	COG0210	DNA helicase
J4N38_19885	COG1289	transmembrane transporter activity
J4N38_19905	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J4N38_19930	COG2827	Endonuclease containing a URI domain
J4N38_19935	COG3132	Protein of unknown function, DUF480
J4N38_19945	COG2926	Belongs to the UPF0265 family
J4N38_19955	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J4N38_19960	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J4N38_19965	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J4N38_19975	COG0247	lactate metabolic process
J4N38_19995	COG0545	Peptidyl-prolyl cis-trans isomerase
J4N38_20005	COG4067	protein conserved in archaea
J4N38_20005	COG0189	ligase activity
J4N38_20015	COG0602	queuosine metabolic process
J4N38_20020	COG1328	CTP reductase activity
J4N38_20055	COG3240	lipase activity
J4N38_20060	COG2814	Major facilitator Superfamily
J4N38_20065	COG1794	racemase activity, acting on amino acids and derivatives
J4N38_20080	COG0183	Belongs to the thiolase family
J4N38_20090	COG1309	transcriptional regulator
J4N38_20130	COG1522	sequence-specific DNA binding
J4N38_20165	COG0515	serine threonine protein kinase
J4N38_20165	COG2815	serine threonine protein kinase
J4N38_20190	COG3501	Rhs element vgr protein
J4N38_20230	COG0739	heme binding
J4N38_20240	COG0840	transmembrane signaling receptor activity
J4N38_20265	COG2759	Belongs to the formate--tetrahydrofolate ligase family
J4N38_20295	COG4172	Belongs to the ABC transporter superfamily
J4N38_20300	COG4239	(ABC) transporter, permease
J4N38_20305	COG4174	ABC transporter (Permease)
J4N38_20310	COG4166	transmembrane transport
J4N38_20320	COG0840	transmembrane signaling receptor activity
J4N38_20325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J4N38_20330	COG1067	ATP-dependent peptidase activity
J4N38_20340	COG4172	Belongs to the ABC transporter superfamily
J4N38_20345	COG0583	DNA-binding transcription factor activity
J4N38_20350	COG1620	l-lactate permease
J4N38_20355	COG1304	FMN binding
J4N38_20370	COG3448	diguanylate cyclase activity
J4N38_20370	COG4175	Glycine betaine
J4N38_20390	COG1012	belongs to the aldehyde dehydrogenase family
J4N38_20395	COG1309	transcriptional regulator
J4N38_20405	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J4N38_20410	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J4N38_20425	COG2200	EAL domain
J4N38_20430	COG2207	Transcriptional regulator
J4N38_20435	COG2814	Major facilitator Superfamily
J4N38_20440	COG0583	DNA-binding transcription factor activity
J4N38_20445	COG3394	polysaccharide catabolic process
J4N38_20450	COG3217	Mosc domain protein beta barrel domain protein
J4N38_20450	COG0633	Ferredoxin
J4N38_20455	COG2205	protein histidine kinase activity
J4N38_20455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N38_20465	COG0657	acetylesterase activity
J4N38_20475	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
J4N38_20475	COG0674	pyruvate-flavodoxin oxidoreductase activity
J4N38_20480	COG1013	pyruvate-flavodoxin oxidoreductase activity
J4N38_20505	COG2197	response regulator
J4N38_20520	COG0516	GMP reductase activity
J4N38_20525	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J4N38_20525	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J4N38_20540	COG3437	response regulator, receiver
J4N38_20545	COG3850	Histidine kinase
J4N38_20545	COG2205	protein histidine kinase activity
J4N38_20545	COG3437	response regulator, receiver
J4N38_20545	COG4999	Histidine kinase
J4N38_20555	COG2172	sigma factor antagonist activity
J4N38_20565	COG1366	Belongs to the anti-sigma-factor antagonist family
J4N38_20570	COG0840	transmembrane signaling receptor activity
J4N38_20590	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
J4N38_20595	COG0513	Belongs to the DEAD box helicase family
J4N38_20605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N38_20605	COG4191	Histidine kinase
J4N38_20610	COG0784	Response regulator, receiver
J4N38_20610	COG3437	response regulator, receiver
J4N38_20615	COG1609	Transcriptional regulator
J4N38_20620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N38_20630	COG1172	Belongs to the binding-protein-dependent transport system permease family
J4N38_20635	COG1129	ABC transporter
J4N38_20640	COG1869	D-ribose catabolic process
J4N38_20660	COG0004	ammonium transporteR
J4N38_20685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N38_20735	COG1609	Transcriptional regulator
J4N38_20740	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J4N38_20745	COG3265	gluconokinase activity
J4N38_20750	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N38_20750	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J4N38_20760	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J4N38_20790	COG5001	Diguanylate cyclase
J4N38_20800	COG3123	guanosine phosphorylase activity
J4N38_20810	COG0668	transmembrane transport
J4N38_20830	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J4N38_20870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4N38_20875	COG4232	protein-disulfide reductase activity
J4N38_20890	COG1280	lysine exporter protein (LysE YggA)
J4N38_20920	COG0443	Heat shock 70 kDa protein
J4N38_20925	COG0583	DNA-binding transcription factor activity
J4N38_20935	COG4948	Mandelate Racemase Muconate Lactonizing
J4N38_20940	COG1396	sequence-specific DNA binding
J4N38_20945	COG5001	Diguanylate cyclase
J4N38_20950	COG0683	leucine binding
J4N38_20955	COG3706	GGDEF domain
J4N38_20970	COG1523	belongs to the glycosyl hydrolase 13 family
J4N38_20990	COG3279	Response regulator of the LytR AlgR family
J4N38_20995	COG3275	phosphorelay sensor kinase activity
J4N38_21010	COG4591	ABC-type transport system involved in lipoprotein release permease component
J4N38_21015	COG1136	(ABC) transporter
J4N38_21050	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N38_21060	COG0583	DNA-binding transcription factor activity
J4N38_21070	COG3530	Putative quorum-sensing-regulated virulence factor
J4N38_21085	COG1686	Belongs to the peptidase S11 family
J4N38_21100	COG3036	rescue of stalled ribosome
J4N38_21105	COG1278	Cold shock
J4N38_21120	COG1017	nitric oxide dioxygenase activity
J4N38_21120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4N38_21125	COG3604	Transcriptional regulator
J4N38_21140	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N38_21150	COG0534	Mate efflux family protein
J4N38_21155	COG0697	spore germination
J4N38_21175	COG0583	DNA-binding transcription factor activity
J4N38_21180	COG5001	Diguanylate cyclase
J4N38_21215	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J4N38_21225	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J4N38_21230	COG0509	glycine decarboxylation via glycine cleavage system
J4N38_21265	COG1132	(ABC) transporter
J4N38_21270	COG0589	response to stress
J4N38_21275	COG2111	Na H antiporter
J4N38_21275	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J4N38_21280	COG1006	Multisubunit Na H antiporter MnhC subunit
J4N38_21285	COG0651	ATP synthesis coupled electron transport
J4N38_21290	COG1863	multisubunit Na H antiporter MnhE subunit
J4N38_21295	COG2212	antiporter activity
J4N38_21300	COG1320	monovalent cation:proton antiporter activity
J4N38_21325	COG0673	inositol 2-dehydrogenase activity
J4N38_21340	COG5553	Cysteine dioxygenase type I
J4N38_21345	COG0840	transmembrane signaling receptor activity
J4N38_21350	COG0840	transmembrane signaling receptor activity
J4N38_21390	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
J4N38_21400	COG0438	transferase activity, transferring glycosyl groups
J4N38_21410	COG1045	serine acetyltransferase
J4N38_21425	COG0438	transferase activity, transferring glycosyl groups
J4N38_21430	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
J4N38_21435	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J4N38_21440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J4N38_21445	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J4N38_21455	COG4989	oxidoreductase activity
J4N38_21465	COG0366	Alpha amylase catalytic
J4N38_21475	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4N38_21480	COG1126	abc transporter atp-binding protein
J4N38_21485	COG0765	amino acid transport
J4N38_21490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N38_21495	COG0765	amino acid transport
J4N38_21500	COG0109	protoheme IX farnesyltransferase activity
J4N38_21505	COG1612	heme a metabolic process
J4N38_21530	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
J4N38_21535	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J4N38_21540	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J4N38_21545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4N38_21560	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
J4N38_21565	COG0574	Belongs to the PEP-utilizing enzyme family
J4N38_21565	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J4N38_21570	COG3314	Sporulation integral membrane protein YlbJ
J4N38_21580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4N38_21605	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N38_21620	COG1741	Belongs to the pirin family
J4N38_21665	COG2205	protein histidine kinase activity
J4N38_21670	COG0745	RESPONSE REGULATOR receiver
J4N38_21695	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J4N38_21705	COG0523	cobalamin synthesis protein
J4N38_21710	COG2988	succinylglutamate desuccinylase activity
J4N38_21720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J4N38_21725	COG2423	ornithine cyclodeaminase activity
J4N38_21735	COG3938	Belongs to the proline racemase family
J4N38_21745	COG2186	Transcriptional regulator
J4N38_21760	COG0601	transmembrane transport
J4N38_21765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N38_21780	COG0006	proline dipeptidase activity
J4N38_21800	COG4934	collagen metabolic process
J4N38_21810	COG3568	Endonuclease Exonuclease Phosphatase
J4N38_21820	COG3291	Pkd domain containing protein
J4N38_21825	COG0513	Belongs to the DEAD box helicase family
J4N38_21835	COG1388	LysM domain
J4N38_21835	COG1376	ErfK ybiS ycfS ynhG family protein
J4N38_21840	COG0415	Belongs to the DNA photolyase family
J4N38_21845	COG0789	Transcriptional regulator
J4N38_21850	COG3272	Protein of unknown function (DUF1722)
J4N38_21855	COG0813	purine-nucleoside phosphorylase activity
J4N38_21885	COG1566	PFAM secretion protein HlyD family protein
J4N38_21890	COG0786	glutamate:sodium symporter activity
J4N38_21905	COG1132	(ABC) transporter
J4N38_21955	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J4N38_21965	COG0259	pyridoxamine-phosphate oxidase activity
J4N38_21995	COG3033	Beta-eliminating lyase
J4N38_22000	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
J4N38_22005	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J4N38_22010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N38_22020	COG1999	signal sequence binding
J4N38_22035	COG1671	Belongs to the UPF0178 family
J4N38_22040	COG0393	Putative heavy-metal-binding
J4N38_22045	COG0583	DNA-binding transcription factor activity
J4N38_22050	COG2814	Major facilitator Superfamily
J4N38_22060	COG0584	glycerophosphoryl diester phosphodiesterase
J4N38_22065	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J4N38_22075	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N38_22100	COG3527	Alpha-acetolactate decarboxylase
J4N38_22105	COG2814	Major facilitator Superfamily
J4N38_22110	COG0028	Belongs to the TPP enzyme family
J4N38_22270	COG1301	dicarboxylic acid transport
J4N38_22275	COG0840	transmembrane signaling receptor activity
J4N38_22290	COG4266	Belongs to the allantoicase family
J4N38_22310	COG2252	PERMEase
J4N38_22325	COG3214	Protein conserved in bacteria
J4N38_22340	COG2205	protein histidine kinase activity
J4N38_22390	COG0109	protoheme IX farnesyltransferase activity
J4N38_22395	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J4N38_22400	COG1845	cytochrome c oxidase, subunit III
J4N38_22405	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J4N38_22410	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J4N38_22415	COG2706	6-phosphogluconolactonase activity
J4N38_22435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N38_22450	COG0459	protein refolding
J4N38_22455	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J4N38_22460	COG0071	Belongs to the small heat shock protein (HSP20) family
J4N38_22465	COG0628	permease
J4N38_22500	COG0668	transmembrane transport
J4N38_22505	COG1803	Methylglyoxal synthase
J4N38_22505	COG1597	lipid kinase activity
J4N38_22535	COG5001	Diguanylate cyclase
J4N38_22535	COG5002	protein histidine kinase activity
J4N38_22555	COG2084	Dehydrogenase
J4N38_22560	COG3622	Belongs to the hyi family
J4N38_22565	COG3960	tartronate-semialdehyde synthase activity
J4N38_22570	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J4N38_22580	COG0583	DNA-binding transcription factor activity
J4N38_22585	COG1288	antiporter activity
J4N38_22595	COG1846	Transcriptional regulator
J4N38_22600	COG0697	spore germination
J4N38_22605	COG1028	Short-chain dehydrogenase reductase Sdr