locus-tag	class	description
J4N37_00010	COG0592	DNA-directed DNA polymerase activity
J4N37_00020	COG0187	DNA topoisomerase II activity
J4N37_00025	COG0071	Belongs to the small heat shock protein (HSP20) family
J4N37_00030	COG3977	Valine--pyruvate aminotransferase
J4N37_00035	COG0366	Alpha amylase catalytic
J4N37_00050	COG2119	membrane
J4N37_00060	COG0425	Belongs to the sulfur carrier protein TusA family
J4N37_00075	COG0604	alcohol dehydrogenase
J4N37_00080	COG0183	Belongs to the thiolase family
J4N37_00090	COG1739	Uncharacterized protein family UPF0029
J4N37_00095	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4N37_00150	COG0583	DNA-binding transcription factor activity
J4N37_00155	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J4N37_00160	COG2960	long-chain fatty acid transporting porin activity
J4N37_00165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N37_00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N37_00175	COG1309	transcriptional regulator
J4N37_00215	COG0546	phosphoglycolate phosphatase activity
J4N37_00230	COG0601	transmembrane transport
J4N37_00235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N37_00245	COG1609	Transcriptional regulator
J4N37_00250	COG0583	DNA-binding transcription factor activity
J4N37_00255	COG2076	Multidrug Resistance protein
J4N37_00265	COG0129	dihydroxy-acid dehydratase activity
J4N37_00270	COG3265	gluconokinase activity
J4N37_00275	COG2610	gluconate transmembrane transporter activity
J4N37_00280	COG0800	Aldolase
J4N37_00285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N37_00295	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J4N37_00305	COG1522	sequence-specific DNA binding
J4N37_00310	COG5001	Diguanylate cyclase
J4N37_00310	COG5002	protein histidine kinase activity
J4N37_00330	COG0589	response to stress
J4N37_00335	COG1528	Iron-storage protein
J4N37_00345	COG2081	HI0933 family
J4N37_00360	COG1322	Protein conserved in bacteria
J4N37_00370	COG3165	ubiquinone biosynthetic process from chorismate
J4N37_00385	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J4N37_00390	COG0805	protein transport
J4N37_00400	COG0084	hydrolase, TatD family'
J4N37_00415	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4N37_00415	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J4N37_00420	COG0218	Necessary for normal cell division and for the maintenance of normal septation
J4N37_00450	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J4N37_00460	COG2204	response regulator
J4N37_00465	COG3852	Histidine kinase
J4N37_00475	COG0174	glutamine synthetase
J4N37_00480	COG1217	gtp-binding protein TYPA
J4N37_00500	COG1490	D-aminoacyl-tRNA deacylase activity
J4N37_00505	COG0456	acetyltransferase
J4N37_00525	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J4N37_00530	COG3031	protein transport across the cell outer membrane
J4N37_00540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4N37_00545	COG1459	type II secretion system
J4N37_00550	COG2165	general secretion pathway protein
J4N37_00555	COG2165	general secretion pathway protein
J4N37_00560	COG2165	general secretion pathway protein
J4N37_00565	COG4795	General secretion pathway protein
J4N37_00570	COG3156	type II secretion system protein K
J4N37_00575	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
J4N37_00580	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
J4N37_00590	COG1218	3'(2'),5'-bisphosphate nucleotidase
J4N37_00595	COG0494	nUDIX hydrolase
J4N37_00605	COG1040	competence protein
J4N37_00620	COG2183	response to ionizing radiation
J4N37_00630	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4N37_00635	COG0840	transmembrane signaling receptor activity
J4N37_00650	COG2233	PERMEase
J4N37_00655	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J4N37_00660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4N37_00665	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J4N37_00670	COG1758	RNA polymerase activity
J4N37_00675	COG0194	GDP metabolic process
J4N37_00690	COG0848	biopolymer transport protein
J4N37_00695	COG0811	peptide transport
J4N37_00715	COG4174	ABC transporter (Permease)
J4N37_00720	COG4239	(ABC) transporter, permease
J4N37_00725	COG0747	negative chemotaxis
J4N37_00730	COG0444	Belongs to the ABC transporter superfamily
J4N37_00735	COG4608	Belongs to the ABC transporter superfamily
J4N37_00755	COG1561	YicC-like family, N-terminal region
J4N37_00760	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J4N37_00765	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J4N37_00770	COG1560	Kdo2-lipid A biosynthetic process
J4N37_00780	COG1309	transcriptional regulator
J4N37_00785	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J4N37_00800	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J4N37_00825	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
J4N37_00830	COG0859	PFAM glycosyl transferase family 9
J4N37_00835	COG0463	Glycosyl transferase, family 2
J4N37_00840	COG0859	PFAM glycosyl transferase family 9
J4N37_00845	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J4N37_00850	COG3642	lipopolysaccharide core region biosynthetic process
J4N37_00855	COG3083	sulfuric ester hydrolase activity
J4N37_00870	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J4N37_00880	COG1086	Polysaccharide biosynthesis protein
J4N37_00885	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J4N37_00890	COG1083	cytidylyl-transferase
J4N37_00910	COG2089	acid synthase
J4N37_00925	COG1519	Transferase
J4N37_00930	COG0859	PFAM glycosyl transferase family 9
J4N37_00935	COG1560	Kdo2-lipid A biosynthetic process
J4N37_00940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4N37_00945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J4N37_00985	COG1091	dTDP-4-dehydrorhamnose reductase activity
J4N37_01005	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4N37_01010	COG1459	type II secretion system
J4N37_01055	COG1450	Type ii and iii secretion system protein
J4N37_01075	COG1216	Glycosyl transferase, family 2
J4N37_01075	COG0438	transferase activity, transferring glycosyl groups
J4N37_01080	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J4N37_01085	COG0175	sulfate reduction
J4N37_01090	COG0471	metal ion transport
J4N37_01090	COG3273	potassium ion transport
J4N37_01095	COG0529	Catalyzes the synthesis of activated sulfate
J4N37_01100	COG2895	sulfate adenylyltransferase (ATP) activity
J4N37_01135	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J4N37_01140	COG0110	maltose O-acetyltransferase activity
J4N37_01145	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J4N37_01155	COG0149	triose-phosphate isomerase activity
J4N37_01180	COG1494	fructose-1,6-bisphosphatase
J4N37_01190	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J4N37_01195	COG1575	Belongs to the MenA family. Type 1 subfamily
J4N37_01215	COG1609	Transcriptional regulator
J4N37_01220	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J4N37_01240	COG0088	Forms part of the polypeptide exit tunnel
J4N37_01310	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J4N37_01325	COG1841	ribosomal large subunit assembly
J4N37_01330	COG0200	Binds to the 23S rRNA
J4N37_01335	COG0201	protein transport
J4N37_01340	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J4N37_01345	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J4N37_01350	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J4N37_01360	COG0202	RNA polymerase activity
J4N37_01365	COG0203	ribosomal protein L17
J4N37_01375	COG0545	Peptidyl-prolyl cis-trans isomerase
J4N37_01390	COG2153	protein acetylation
J4N37_01395	COG0513	Belongs to the DEAD box helicase family
J4N37_01405	COG0737	Belongs to the 5'-nucleotidase family
J4N37_01410	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J4N37_01410	COG1648	precorrin-2 dehydrogenase activity
J4N37_01425	COG0471	metal ion transport
J4N37_01425	COG3273	potassium ion transport
J4N37_01430	COG0529	Catalyzes the synthesis of activated sulfate
J4N37_01450	COG1136	(ABC) transporter
J4N37_01465	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
J4N37_01475	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N37_01480	COG0729	surface antigen
J4N37_01490	COG2105	PFAM AIG2 family protein
J4N37_01500	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J4N37_01510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J4N37_01515	COG0163	prenyltransferase activity
J4N37_01525	COG1178	ABC-type Fe3 transport system permease component
J4N37_01530	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
J4N37_01545	COG2358	TRAP transporter, solute receptor (TAXI family
J4N37_01565	COG0142	geranyltranstransferase activity
J4N37_01570	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J4N37_01585	COG2966	Psort location CytoplasmicMembrane, score
J4N37_01590	COG3610	response to peptide
J4N37_01595	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J4N37_01615	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J4N37_01620	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4N37_01625	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
J4N37_01630	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
J4N37_01650	COG0473	3-isopropylmalate dehydrogenase activity
J4N37_01655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J4N37_01675	COG0583	DNA-binding transcription factor activity
J4N37_01680	COG1022	Amp-dependent synthetase and ligase
J4N37_01685	COG0028	Belongs to the TPP enzyme family
J4N37_01690	COG0440	acetolactate synthase activity
J4N37_01695	COG3706	GGDEF domain
J4N37_01705	COG0469	pyruvate kinase activity
J4N37_01710	COG1349	DNA-binding transcription factor activity
J4N37_01715	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J4N37_01725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N37_01730	COG3722	fumarate hydratase activity
J4N37_01740	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N37_01740	COG2213	PTS system mannitol-specific
J4N37_01775	COG0358	DNA primase activity
J4N37_01780	COG1610	YqeY-like protein
J4N37_01785	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J4N37_01790	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J4N37_01795	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J4N37_01800	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J4N37_01805	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J4N37_01810	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J4N37_01825	COG3409	Peptidoglycan-binding domain 1 protein
J4N37_01825	COG3267	Type II secretory pathway component ExeA
J4N37_01835	COG4991	sh3 domain protein
J4N37_01840	COG0306	phosphate transporter
J4N37_01845	COG1392	Phosphate transport regulator
J4N37_01850	COG3025	triphosphatase activity
J4N37_01855	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J4N37_01865	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J4N37_01875	COG1538	Outer membrane efflux protein
J4N37_01880	COG0494	nUDIX hydrolase
J4N37_01885	COG3151	Protein conserved in bacteria
J4N37_01895	COG3150	esterase
J4N37_01905	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J4N37_01910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4N37_01915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4N37_01920	COG3105	Protein conserved in bacteria
J4N37_01925	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J4N37_01940	COG0723	plastoquinol--plastocyanin reductase activity
J4N37_01945	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J4N37_01950	COG2857	Cytochrome c1
J4N37_01955	COG0625	glutathione transferase activity
J4N37_01960	COG2969	positive regulation of protein catabolic process
J4N37_01965	COG2823	Periplasmic or secreted lipoprotein
J4N37_01970	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J4N37_01985	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J4N37_02000	COG3116	cell division
J4N37_02005	COG0768	penicillin binding
J4N37_02010	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J4N37_02015	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J4N37_02020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J4N37_02030	COG0772	Belongs to the SEDS family
J4N37_02045	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J4N37_02050	COG0849	cell division
J4N37_02055	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J4N37_02060	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J4N37_02075	COG0494	nUDIX hydrolase
J4N37_02085	COG0505	Belongs to the CarA family
J4N37_02090	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J4N37_02105	COG0730	response to heat
J4N37_02110	COG0583	DNA-binding transcription factor activity
J4N37_02115	COG2860	membrane
J4N37_02140	COG0493	'glutamate synthase
J4N37_02145	COG0069	glutamate synthase activity
J4N37_02145	COG0070	glutamate synthase
J4N37_02145	COG0067	glutamate synthase
J4N37_02155	COG0067	glutamate synthase
J4N37_02155	COG0069	glutamate synthase activity
J4N37_02155	COG0070	glutamate synthase
J4N37_02160	COG1242	4 iron, 4 sulfur cluster binding
J4N37_02165	COG5001	Diguanylate cyclase
J4N37_02165	COG3706	GGDEF domain
J4N37_02165	COG2203	Gaf domain
J4N37_02165	COG4251	negative regulation of phosphorylation
J4N37_02170	COG0784	Response regulator, receiver
J4N37_02170	COG2198	Histidine kinase
J4N37_02170	COG5002	protein histidine kinase activity
J4N37_02180	COG0745	RESPONSE REGULATOR receiver
J4N37_02190	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J4N37_02205	COG0083	homoserine kinase activity
J4N37_02210	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J4N37_02245	COG1115	amino acid carrier protein
J4N37_02250	COG3022	response to hydroperoxide
J4N37_02260	COG0513	Belongs to the DEAD box helicase family
J4N37_02275	COG0716	FMN binding
J4N37_02280	COG4974	Belongs to the 'phage' integrase family
J4N37_02285	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4N37_02290	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J4N37_02315	COG0667	Aldo Keto reductase
J4N37_02335	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
J4N37_02340	COG0730	response to heat
J4N37_02355	COG1283	sodium-dependent phosphate transmembrane transporter activity
J4N37_02360	COG0583	DNA-binding transcription factor activity
J4N37_02365	COG0640	Transcriptional regulator
J4N37_02370	COG0268	Binds directly to 16S ribosomal RNA
J4N37_02375	COG0728	peptidoglycan biosynthetic process
J4N37_02380	COG0196	riboflavin kinase activity
J4N37_02395	COG1047	Peptidyl-prolyl cis-trans
J4N37_02400	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J4N37_02405	COG3279	Response regulator of the LytR AlgR family
J4N37_02410	COG3275	phosphorelay sensor kinase activity
J4N37_02415	COG1966	Carbon starvation protein
J4N37_02435	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
J4N37_02445	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4N37_02450	COG1605	Chorismate mutase
J4N37_02450	COG0287	Prephenate dehydrogenase
J4N37_02455	COG0739	heme binding
J4N37_02465	COG0488	(ABC) transporter
J4N37_02480	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
J4N37_02485	COG1605	Chorismate mutase
J4N37_02485	COG0077	Prephenate dehydratase
J4N37_02490	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J4N37_02495	COG0741	lytic transglycosylase activity
J4N37_02500	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N37_02505	COG0564	pseudouridine synthase activity
J4N37_02510	COG1496	oxidoreductase activity
J4N37_02515	COG0542	response to heat
J4N37_02560	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
J4N37_02570	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J4N37_02575	COG0826	peptidase U32
J4N37_02585	COG0745	RESPONSE REGULATOR receiver
J4N37_02590	COG5002	protein histidine kinase activity
J4N37_02600	COG0248	Ppx GppA phosphatase
J4N37_02605	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J4N37_02610	COG0573	inorganic phosphate transmembrane transporter activity
J4N37_02615	COG0581	inorganic phosphate transmembrane transporter activity
J4N37_02620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4N37_02625	COG0704	Plays a role in the regulation of phosphate uptake
J4N37_02655	COG0450	alkyl hydroperoxide reductase
J4N37_02660	COG0583	DNA-binding transcription factor activity
J4N37_02665	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J4N37_02675	COG0517	IMP dehydrogenase activity
J4N37_02700	COG1862	Preprotein translocase
J4N37_02705	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N37_02710	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N37_02715	COG0483	inositol monophosphate 1-phosphatase activity
J4N37_02735	COG0822	iron-sulfur transferase activity
J4N37_02740	COG0316	Belongs to the HesB IscA family
J4N37_02755	COG0633	Ferredoxin
J4N37_02760	COG2975	iron-sulfur cluster assembly
J4N37_02795	COG2976	Protein conserved in bacteria
J4N37_02800	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N37_02815	COG2199	diguanylate cyclase activity
J4N37_02815	COG2203	Gaf domain
J4N37_02830	COG0517	IMP dehydrogenase activity
J4N37_02830	COG0516	GMP reductase activity
J4N37_02840	COG1757	Na H antiporter
J4N37_02850	COG1584	GPR1 FUN34 yaaH family protein
J4N37_02855	COG1115	amino acid carrier protein
J4N37_02865	COG0583	DNA-binding transcription factor activity
J4N37_02895	COG2873	o-acetylhomoserine
J4N37_02900	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J4N37_02920	COG1289	transmembrane transporter activity
J4N37_02925	COG0583	DNA-binding transcription factor activity
J4N37_02940	COG2867	negative regulation of translational initiation
J4N37_02945	COG2914	Belongs to the UPF0125 (RnfH) family
J4N37_02950	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4N37_02960	COG0497	DNA recombination
J4N37_02980	COG1301	dicarboxylic acid transport
J4N37_03020	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J4N37_03025	COG0590	tRNA wobble adenosine to inosine editing
J4N37_03035	COG0047	phosphoribosylformylglycinamidine synthase activity
J4N37_03035	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J4N37_03055	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4N37_03060	COG2252	PERMEase
J4N37_03065	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
J4N37_03070	COG1073	alpha beta
J4N37_03085	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J4N37_03090	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J4N37_03095	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4N37_03095	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4N37_03120	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J4N37_03125	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J4N37_03135	COG0142	geranyltranstransferase activity
J4N37_03145	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J4N37_03160	COG0583	DNA-binding transcription factor activity
J4N37_03170	COG2363	Small membrane protein
J4N37_03190	COG1611	Belongs to the LOG family
J4N37_03215	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
J4N37_03220	COG0737	Belongs to the 5'-nucleotidase family
J4N37_03230	COG1464	Belongs to the NlpA lipoprotein family
J4N37_03235	COG2011	ABC-type metal ion transport system permease component
J4N37_03240	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J4N37_03245	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J4N37_03255	COG1263	PTS System
J4N37_03255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N37_03260	COG0366	Alpha amylase catalytic
J4N37_03275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4N37_03280	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J4N37_03300	COG1686	Belongs to the peptidase S11 family
J4N37_03305	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J4N37_03310	COG0772	Belongs to the SEDS family
J4N37_03315	COG0768	penicillin binding
J4N37_03325	COG0799	negative regulation of ribosome biogenesis
J4N37_03330	COG1466	dna polymerase III delta subunit
J4N37_03335	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
J4N37_03345	COG2888	peptidyl-tyrosine sulfation
J4N37_03350	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J4N37_03355	COG4535	Mg2 and Co2 transporter CorC
J4N37_03365	COG1702	phosphate starvation-inducible protein PhoH
J4N37_03375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N37_03495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J4N37_03520	COG2890	protein-(glutamine-N5) methyltransferase activity
J4N37_03525	COG3094	Invasion gene expression up-regulator, SirB
J4N37_03530	COG2912	Transglutaminase-like superfamily
J4N37_03540	COG0737	Belongs to the 5'-nucleotidase family
J4N37_03545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J4N37_03550	COG1187	pseudouridine synthase activity
J4N37_03555	COG2840	Smr protein MutS2
J4N37_03600	COG2217	Heavy metal translocating P-type atpase
J4N37_03600	COG2608	mercury ion transmembrane transporter activity
J4N37_03650	COG2747	anti-sigma28 factor FlgM
J4N37_03660	COG0784	Response regulator, receiver
J4N37_03660	COG0835	chemotaxis
J4N37_03665	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J4N37_03670	COG1815	bacterial-type flagellum-dependent cell motility
J4N37_03675	COG1558	bacterial-type flagellum-dependent cell motility
J4N37_03685	COG1749	Flagellar hook protein flgE
J4N37_03690	COG4787	bacterial-type flagellum-dependent cell motility
J4N37_03700	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J4N37_03705	COG1706	bacterial-type flagellum-dependent cell motility
J4N37_03710	COG1705	Flagellar rod assembly protein muramidase FlgJ
J4N37_03710	COG3951	Flagellar rod assembly protein muramidase FlgJ
J4N37_03725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N37_03730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N37_03735	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N37_03740	COG2190	(PTS) system
J4N37_03745	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J4N37_03750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N37_03755	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J4N37_03760	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
J4N37_03790	COG0330	HflC and HflK could
J4N37_03795	COG3118	belongs to the thioredoxin family
J4N37_03805	COG0300	oxidoreductase activity
J4N37_03810	COG1090	epimerase
J4N37_03840	COG0622	Phosphoesterase
J4N37_03860	COG3710	Transcriptional regulator
J4N37_03875	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J4N37_03880	COG3104	oligopeptide transport
J4N37_03885	COG0250	Participates in transcription elongation, termination and antitermination
J4N37_03890	COG0367	asparagine synthase
J4N37_03895	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J4N37_03895	COG4651	solute:proton antiporter activity
J4N37_03900	COG1846	Transcriptional regulator
J4N37_03900	COG1940	carbohydrate kinase activity
J4N37_03905	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J4N37_03910	COG1263	PTS System
J4N37_03910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N37_03910	COG2190	(PTS) system
J4N37_03925	COG0735	belongs to the Fur family
J4N37_03945	COG0596	Alpha beta hydrolase
J4N37_03950	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
J4N37_03955	COG0033	Phosphoglucomutase
J4N37_03965	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J4N37_03980	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
J4N37_03985	COG1053	succinate dehydrogenase
J4N37_03995	COG0567	Dehydrogenase, E1 component
J4N37_04000	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4N37_04015	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J4N37_04020	COG1121	(ABC) transporter
J4N37_04025	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
J4N37_04035	COG1918	ferrous iron import across plasma membrane
J4N37_04065	COG3102	Protein conserved in bacteria
J4N37_04070	COG0788	formyltetrahydrofolate deformylase activity
J4N37_04080	COG1199	ATP-dependent helicase activity
J4N37_04085	COG1214	PFAM Peptidase M22, glycoprotease
J4N37_04100	COG2267	carboxylic ester hydrolase activity
J4N37_04105	COG0318	PFAM AMP-dependent synthetase and ligase
J4N37_04110	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
J4N37_04115	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
J4N37_04120	COG2894	cell division
J4N37_04130	COG3100	YcgL domain-containing protein
J4N37_04135	COG2951	lytic endotransglycosylase activity
J4N37_04145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4N37_04150	COG2852	Protein conserved in bacteria
J4N37_04335	COG1181	Belongs to the D-alanine--D-alanine ligase family
J4N37_04355	COG1716	ATPase activity
J4N37_04380	COG3064	Membrane
J4N37_04380	COG4991	sh3 domain protein
J4N37_04380	COG0515	serine threonine protein kinase
J4N37_04390	COG2169	Transcriptional regulator
J4N37_04395	COG1253	flavin adenine dinucleotide binding
J4N37_04400	COG0513	Belongs to the DEAD box helicase family
J4N37_04405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N37_04410	COG0569	domain protein
J4N37_04415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4N37_04430	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J4N37_04435	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J4N37_04440	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J4N37_04470	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J4N37_04475	COG0776	regulation of translation
J4N37_04480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4N37_04485	COG1555	photosystem II stabilization
J4N37_04505	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
J4N37_04510	COG0436	Aminotransferase
J4N37_04515	COG1169	isochorismate synthase
J4N37_04525	COG0596	Alpha beta hydrolase
J4N37_04530	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
J4N37_04545	COG2190	(PTS) system
J4N37_04545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N37_04545	COG1263	PTS System
J4N37_04550	COG0583	DNA-binding transcription factor activity
J4N37_04560	COG2855	membrane
J4N37_04615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N37_04625	COG3385	transposase activity
J4N37_04650	COG1522	sequence-specific DNA binding
J4N37_04660	COG1946	Acyl-CoA thioesterase
J4N37_04665	COG3126	Type III secretion system lipoprotein chaperone (YscW)
J4N37_04690	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J4N37_04695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4N37_04700	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J4N37_04705	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
J4N37_04715	COG0617	tRNA 3'-terminal CCA addition
J4N37_04715	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J4N37_04715	COG0517	IMP dehydrogenase activity
J4N37_04745	COG0537	adenosine 5'-monophosphoramidase activity
J4N37_04775	COG1252	NADH dehydrogenase
J4N37_04790	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J4N37_04800	COG4591	ABC-type transport system involved in lipoprotein release permease component
J4N37_04805	COG1136	(ABC) transporter
J4N37_04810	COG4591	ABC-type transport system involved in lipoprotein release permease component
J4N37_04820	COG0658	competence protein
J4N37_04820	COG2333	competence protein COMEC
J4N37_04825	COG1132	(ABC) transporter
J4N37_04845	COG2719	SpoVR family
J4N37_04850	COG2718	Belongs to the UPF0229 family
J4N37_04855	COG2766	serine protein kinase
J4N37_04875	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J4N37_04885	COG1882	Formate acetyltransferase
J4N37_04915	COG0708	Exodeoxyribonuclease III
J4N37_04920	COG0840	transmembrane signaling receptor activity
J4N37_04930	COG3923	Primosomal replication protein n
J4N37_04935	COG0730	response to heat
J4N37_04940	COG1199	ATP-dependent helicase activity
J4N37_04950	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
J4N37_04955	COG1187	pseudouridine synthase activity
J4N37_04965	COG1278	Cold shock
J4N37_04975	COG0542	response to heat
J4N37_04985	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J4N37_05015	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4N37_05020	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J4N37_05025	COG0297	glycogen (starch) synthase activity
J4N37_05045	COG3070	regulator of competence-specific genes
J4N37_05060	COG0745	RESPONSE REGULATOR receiver
J4N37_05065	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J4N37_05070	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4N37_05080	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
J4N37_05085	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J4N37_05105	COG0189	ligase activity
J4N37_05105	COG4067	protein conserved in archaea
J4N37_05120	COG1801	Protein of unknown function DUF72
J4N37_05130	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J4N37_05135	COG0840	transmembrane signaling receptor activity
J4N37_05140	COG0632	four-way junction helicase activity
J4N37_05150	COG1271	oxidase subunit
J4N37_05155	COG1294	oxidase, subunit
J4N37_05160	COG4890	Cyd operon protein YbgT
J4N37_05170	COG0824	Thioesterase
J4N37_05175	COG0811	peptide transport
J4N37_05190	COG0823	Involved in the tonB-independent uptake of proteins
J4N37_05195	COG2885	chlorophyll binding
J4N37_05200	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
J4N37_05215	COG3766	membrane
J4N37_05225	COG0754	glutathionylspermidine amidase activity
J4N37_05240	COG1858	cytochrome C peroxidase
J4N37_05260	COG5002	protein histidine kinase activity
J4N37_05260	COG0784	Response regulator, receiver
J4N37_05290	COG0789	Transcriptional regulator
J4N37_05295	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J4N37_05300	COG2824	Alkylphosphonate utilization operon protein PhnA
J4N37_05310	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J4N37_05325	COG2076	Multidrug Resistance protein
J4N37_05350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N37_05355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N37_05380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N37_05400	COG2176	DNA-directed DNA polymerase activity
J4N37_05405	COG0517	IMP dehydrogenase activity
J4N37_05410	COG2186	Transcriptional regulator
J4N37_05415	COG1028	Short-chain dehydrogenase reductase Sdr
J4N37_05420	COG2186	Transcriptional regulator
J4N37_05455	COG3568	Endonuclease Exonuclease Phosphatase
J4N37_05470	COG4934	collagen metabolic process
J4N37_05495	COG1917	Cupin 2, conserved barrel domain protein
J4N37_05500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N37_05505	COG0800	Aldolase
J4N37_05510	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N37_05520	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J4N37_05540	COG0840	transmembrane signaling receptor activity
J4N37_05560	COG3009	Protein conserved in bacteria
J4N37_05565	COG3008	intermembrane lipid transfer
J4N37_05565	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J4N37_05570	COG2995	paraquat-inducible protein a
J4N37_05575	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J4N37_05590	COG4232	protein-disulfide reductase activity
J4N37_05595	COG3118	belongs to the thioredoxin family
J4N37_05600	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J4N37_05610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N37_05640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N37_05650	COG0577	efflux transmembrane transporter activity
J4N37_05650	COG1136	(ABC) transporter
J4N37_05655	COG1136	(ABC) transporter
J4N37_05655	COG0577	efflux transmembrane transporter activity
J4N37_05660	COG1136	(ABC) transporter
J4N37_05660	COG0577	efflux transmembrane transporter activity
J4N37_05665	COG1609	Transcriptional regulator
J4N37_05670	COG0366	Alpha amylase catalytic
J4N37_05675	COG2182	Extracellular solute-binding protein
J4N37_05680	COG2176	DNA-directed DNA polymerase activity
J4N37_05700	COG0583	DNA-binding transcription factor activity
J4N37_05740	COG1172	Belongs to the binding-protein-dependent transport system permease family
J4N37_05745	COG1129	ABC transporter
J4N37_05785	COG3850	Histidine kinase
J4N37_05785	COG5002	protein histidine kinase activity
J4N37_05790	COG0745	RESPONSE REGULATOR receiver
J4N37_05795	COG0463	Glycosyl transferase, family 2
J4N37_05800	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
J4N37_05810	COG2964	Protein conserved in bacteria
J4N37_05825	COG0446	pyridine nucleotide-disulphide oxidoreductase
J4N37_05830	COG1032	radical SAM domain protein
J4N37_05835	COG2203	Gaf domain
J4N37_05835	COG4251	negative regulation of phosphorylation
J4N37_05835	COG5001	Diguanylate cyclase
J4N37_05835	COG3706	GGDEF domain
J4N37_05850	COG0583	DNA-binding transcription factor activity
J4N37_05865	COG2350	Protein conserved in bacteria
J4N37_05870	COG1607	acyl-coa hydrolase
J4N37_05895	COG1301	dicarboxylic acid transport
J4N37_05900	COG0159	tryptophan synthase activity
J4N37_05910	COG0135	phosphoribosylanthranilate isomerase activity
J4N37_05910	COG0134	indole-3-glycerol-phosphate synthase activity
J4N37_05920	COG0512	Glutamine amidotransferase of anthranilate synthase
J4N37_05925	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J4N37_05935	COG0613	PHP domain protein
J4N37_05940	COG0009	L-threonylcarbamoyladenylate synthase
J4N37_05950	COG1187	pseudouridine synthase activity
J4N37_05970	COG0417	DNA replication proofreading
J4N37_05985	COG2197	response regulator
J4N37_05990	COG0322	excinuclease ABC activity
J4N37_06030	COG0019	diaminopimelate decarboxylase activity
J4N37_06055	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4N37_06060	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4N37_06065	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4N37_06085	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
J4N37_06095	COG0437	4 iron, 4 sulfur cluster binding
J4N37_06100	COG3301	Polysulphide reductase, NrfD
J4N37_06105	COG1138	Cytochrome C-type biogenesis protein
J4N37_06110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4N37_06115	COG3088	subunit of a heme lyase
J4N37_06115	COG4235	cytochrome complex assembly
J4N37_06125	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J4N37_06150	COG2989	Protein conserved in bacteria
J4N37_06155	COG3108	Peptidase M15
J4N37_06160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4N37_06175	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J4N37_06200	COG1846	Transcriptional regulator
J4N37_06205	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N37_06210	COG0840	transmembrane signaling receptor activity
J4N37_06230	COG1448	Aminotransferase
J4N37_06235	COG2770	Histidine kinase
J4N37_06235	COG3437	response regulator, receiver
J4N37_06250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N37_06265	COG0017	Asparaginyl-tRNA synthetase
J4N37_06270	COG0840	transmembrane signaling receptor activity
J4N37_06275	COG0720	synthase
J4N37_06280	COG0531	amino acid
J4N37_06285	COG1280	lysine exporter protein (LysE YggA)
J4N37_06290	COG1560	Kdo2-lipid A biosynthetic process
J4N37_06295	COG0471	metal ion transport
J4N37_06300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N37_06300	COG4191	Histidine kinase
J4N37_06310	COG3706	GGDEF domain
J4N37_06315	COG5001	Diguanylate cyclase
J4N37_06325	COG1280	lysine exporter protein (LysE YggA)
J4N37_06330	COG1328	CTP reductase activity
J4N37_06335	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J4N37_06345	COG0861	Integral membrane protein TerC family
J4N37_06355	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J4N37_06360	COG4221	oxidoreductase activity
J4N37_06365	COG3706	GGDEF domain
J4N37_06375	COG1454	alcohol dehydrogenase
J4N37_06380	COG0814	amino acid
J4N37_06395	COG1120	ATPase activity
J4N37_06400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4N37_06405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N37_06410	COG4774	siderophore transport
J4N37_06420	COG1132	(ABC) transporter
J4N37_06425	COG1132	(ABC) transporter
J4N37_06505	COG0583	DNA-binding transcription factor activity
J4N37_06530	COG0443	Heat shock 70 kDa protein
J4N37_06535	COG0443	Heat shock 70 kDa protein
J4N37_06545	COG2199	diguanylate cyclase activity
J4N37_06585	COG0243	molybdopterin cofactor binding
J4N37_06590	COG0437	4 iron, 4 sulfur cluster binding
J4N37_06595	COG3302	dmso reductase anchor subunit
J4N37_06610	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J4N37_06615	COG1643	Atp-dependent helicase
J4N37_06630	COG0813	purine-nucleoside phosphorylase activity
J4N37_06655	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4N37_06665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N37_06670	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
J4N37_06675	COG2909	trisaccharide binding
J4N37_06710	COG1280	lysine exporter protein (LysE YggA)
J4N37_06720	COG1115	amino acid carrier protein
J4N37_06745	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
J4N37_06755	COG0625	glutathione transferase activity
J4N37_06800	COG0589	response to stress
J4N37_06805	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
J4N37_06810	COG0668	transmembrane transport
J4N37_06815	COG3247	response to pH
J4N37_06830	COG1846	Transcriptional regulator
J4N37_06850	COG0110	maltose O-acetyltransferase activity
J4N37_06870	COG2205	protein histidine kinase activity
J4N37_06870	COG3437	response regulator, receiver
J4N37_06870	COG3850	Histidine kinase
J4N37_06870	COG4999	Histidine kinase
J4N37_06880	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J4N37_06885	COG1215	transferase activity, transferring glycosyl groups
J4N37_06890	COG0297	glycogen (starch) synthase activity
J4N37_06920	COG0438	transferase activity, transferring glycosyl groups
J4N37_06930	COG2204	response regulator
J4N37_06950	COG2885	chlorophyll binding
J4N37_06960	COG1793	dna ligase
J4N37_06970	COG0534	Mate efflux family protein
J4N37_06975	COG0307	riboflavin synthase, alpha
J4N37_06985	COG3001	Fructosamine kinase
J4N37_06990	COG2201	protein-glutamate methylesterase activity
J4N37_06995	COG3706	GGDEF domain
J4N37_07005	COG0791	NLP P60 protein
J4N37_07010	COG0840	transmembrane signaling receptor activity
J4N37_07015	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J4N37_07015	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J4N37_07125	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
J4N37_07130	COG0372	Belongs to the citrate synthase family
J4N37_07140	COG2828	Protein conserved in bacteria
J4N37_07170	COG0561	phosphatase activity
J4N37_07175	COG0602	queuosine metabolic process
J4N37_07185	COG3706	GGDEF domain
J4N37_07215	COG2885	chlorophyll binding
J4N37_07215	COG3047	cAMP biosynthetic process
J4N37_07235	COG0840	transmembrane signaling receptor activity
J4N37_07240	COG1254	Belongs to the acylphosphatase family
J4N37_07245	COG2920	part of a sulfur-relay system
J4N37_07255	COG0670	Belongs to the BI1 family
J4N37_07260	COG1126	abc transporter atp-binding protein
J4N37_07265	COG0765	amino acid transport
J4N37_07270	COG4597	amino acid ABC transporter
J4N37_07275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N37_07290	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4N37_07315	COG3008	intermembrane lipid transfer
J4N37_07320	COG2995	paraquat-inducible protein a
J4N37_07325	COG1132	(ABC) transporter
J4N37_07330	COG1956	GAF domain-containing protein
J4N37_07335	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
J4N37_07350	COG0308	aminopeptidase N
J4N37_07360	COG2902	Dehydrogenase
J4N37_07385	COG0488	(ABC) transporter
J4N37_07405	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J4N37_07410	COG1067	ATP-dependent peptidase activity
J4N37_07440	COG0784	Response regulator, receiver
J4N37_07440	COG2205	protein histidine kinase activity
J4N37_07455	COG3278	Belongs to the heme-copper respiratory oxidase family
J4N37_07470	COG2010	Cytochrome c
J4N37_07480	COG2217	Heavy metal translocating P-type atpase
J4N37_07495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N37_07500	COG0589	response to stress
J4N37_07525	COG3842	ATPase activity
J4N37_07535	COG1177	transmembrane transport
J4N37_07545	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J4N37_07550	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J4N37_07570	COG3209	COG3209 Rhs family protein
J4N37_07585	COG0437	4 iron, 4 sulfur cluster binding
J4N37_07590	COG3383	formate dehydrogenase (NAD+) activity
J4N37_07590	COG0243	molybdopterin cofactor binding
J4N37_07600	COG3381	protein complex oligomerization
J4N37_07620	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J4N37_07630	COG0488	(ABC) transporter
J4N37_07645	COG4191	Histidine kinase
J4N37_07650	COG2204	response regulator
J4N37_07660	COG4662	Binding-protein-dependent transport system inner membrane component
J4N37_07665	COG3842	ATPase activity
J4N37_07675	COG0303	'Molybdopterin
J4N37_07690	COG1940	carbohydrate kinase activity
J4N37_07695	COG3148	PFAM DTW domain containing protein
J4N37_07760	COG0730	response to heat
J4N37_07770	COG2358	TRAP transporter, solute receptor (TAXI family
J4N37_07775	COG3437	response regulator, receiver
J4N37_07780	COG1012	belongs to the aldehyde dehydrogenase family
J4N37_07785	COG3284	Transcriptional regulator
J4N37_07810	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J4N37_07815	COG0363	glucosamine-6-phosphate deaminase activity
J4N37_07820	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J4N37_07830	COG4774	siderophore transport
J4N37_07835	COG4565	transcriptional regulatory protein
J4N37_07840	COG3290	protein histidine kinase activity
J4N37_07855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N37_07875	COG0583	DNA-binding transcription factor activity
J4N37_07895	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4N37_07900	COG0583	DNA-binding transcription factor activity
J4N37_07910	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
J4N37_07915	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J4N37_07920	COG0697	spore germination
J4N37_07925	COG2207	Transcriptional regulator
J4N37_07960	COG0583	DNA-binding transcription factor activity
J4N37_07965	COG2814	Major facilitator Superfamily
J4N37_07975	COG0702	epimerase
J4N37_07980	COG0583	DNA-binding transcription factor activity
J4N37_07985	COG1404	Belongs to the peptidase S8 family
J4N37_07990	COG1858	cytochrome C peroxidase
J4N37_08005	COG0527	aspartate kinase activity
J4N37_08010	COG0662	Cupin 2, conserved barrel domain protein
J4N37_08015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J4N37_08020	COG0456	acetyltransferase
J4N37_08025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N37_08035	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
J4N37_08040	COG0534	Mate efflux family protein
J4N37_08045	COG0215	cysteine-tRNA ligase activity
J4N37_08050	COG1368	sulfuric ester hydrolase activity
J4N37_08085	COG2801	Transposase and inactivated derivatives
J4N37_08100	COG2801	Transposase and inactivated derivatives
J4N37_08200	COG2801	Transposase and inactivated derivatives
J4N37_08260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N37_08430	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J4N37_08470	COG2801	Transposase and inactivated derivatives
J4N37_08835	COG1280	lysine exporter protein (LysE YggA)
J4N37_08975	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J4N37_09250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N37_09265	COG3106	COG3106 Predicted ATPase
J4N37_09280	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J4N37_09285	COG2205	protein histidine kinase activity
J4N37_09285	COG0784	Response regulator, receiver
J4N37_09295	COG0494	nUDIX hydrolase
J4N37_09300	COG0814	amino acid
J4N37_09305	COG1760	l-serine dehydratase
J4N37_09310	COG3300	MHYT domain
J4N37_09310	COG5001	Diguanylate cyclase
J4N37_09325	COG2197	response regulator
J4N37_09340	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
J4N37_09345	COG3063	Type IV pilus biogenesis stability protein PilW
J4N37_09365	COG1451	nucleotide metabolic process
J4N37_09370	COG3475	LICD family
J4N37_09375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4N37_09380	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J4N37_09410	COG0583	DNA-binding transcription factor activity
J4N37_09440	COG4139	cobalamin transport
J4N37_09465	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J4N37_09475	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J4N37_09480	COG0702	epimerase
J4N37_09485	COG2925	Exonuclease
J4N37_09495	COG1346	cytolysis
J4N37_09540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4N37_09540	COG0072	phenylalanine-tRNA ligase activity
J4N37_09575	COG0251	oxidation-reduction process
J4N37_09595	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J4N37_09620	COG2188	Transcriptional regulator
J4N37_09630	COG0010	Belongs to the arginase family
J4N37_09640	COG2986	histidine ammonia-lyase
J4N37_09655	COG0247	lactate metabolic process
J4N37_09655	COG0277	FAD linked oxidase domain protein
J4N37_09715	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
J4N37_09720	COG1643	Atp-dependent helicase
J4N37_09730	COG2949	membrane
J4N37_09735	COG0471	metal ion transport
J4N37_09760	COG0492	ferredoxin-NADP+ reductase activity
J4N37_09765	COG4988	ABC transporter
J4N37_09770	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J4N37_09780	COG2610	gluconate transmembrane transporter activity
J4N37_09785	COG0583	DNA-binding transcription factor activity
J4N37_09800	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J4N37_09810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N37_09810	COG4191	Histidine kinase
J4N37_09825	COG3070	regulator of competence-specific genes
J4N37_09835	COG2431	L-lysine efflux transmembrane transporter activity
J4N37_09845	COG0076	glutamate decarboxylase activity
J4N37_09850	COG1737	Transcriptional regulator
J4N37_09860	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J4N37_09870	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J4N37_09905	COG0534	Mate efflux family protein
J4N37_09910	COG0702	epimerase
J4N37_09915	COG1609	Transcriptional regulator
J4N37_09925	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N37_09935	COG2814	Major facilitator Superfamily
J4N37_09940	COG1187	pseudouridine synthase activity
J4N37_09945	COG1061	Type III restriction enzyme res subunit
J4N37_09970	COG0463	Glycosyl transferase, family 2
J4N37_09970	COG1216	Glycosyl transferase, family 2
J4N37_10000	COG3313	Fe-S protein
J4N37_10010	COG0659	secondary active sulfate transmembrane transporter activity
J4N37_10035	COG0493	'glutamate synthase
J4N37_10045	COG0398	Pfam SNARE associated Golgi protein
J4N37_10050	COG4134	Bacterial extracellular solute-binding protein
J4N37_10055	COG4135	transport system, permease component
J4N37_10060	COG4136	ATPase activity
J4N37_10065	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J4N37_10075	COG3604	Transcriptional regulator
J4N37_10080	COG1151	hydroxylamine reductase activity
J4N37_10085	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4N37_10095	COG0564	pseudouridine synthase activity
J4N37_10105	COG0733	neurotransmitter:sodium symporter activity
J4N37_10115	COG0626	cystathionine gamma-synthase activity
J4N37_10120	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J4N37_10125	COG5380	lipid catabolic process
J4N37_10130	COG2818	Glycosylase
J4N37_10160	COG1842	Phage shock protein A
J4N37_10165	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
J4N37_10175	COG4168	peptide transport system, permease
J4N37_10180	COG4171	peptide transport system, permease
J4N37_10190	COG4172	Belongs to the ABC transporter superfamily
J4N37_10200	COG1227	inorganic diphosphatase activity
J4N37_10215	COG0243	molybdopterin cofactor binding
J4N37_10220	COG3005	denitrification pathway
J4N37_10225	COG4459	periplasmic nitrate reductase
J4N37_10230	COG0390	transport system, permease component
J4N37_10240	COG2116	formate transmembrane transporter activity
J4N37_10265	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J4N37_10270	COG1435	thymidine kinase activity
J4N37_10275	COG0215	cysteine-tRNA ligase activity
J4N37_10280	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J4N37_10285	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4N37_10290	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J4N37_10295	COG3012	SEC-C Motif Domain Protein
J4N37_10300	COG0140	phosphoribosyl-ATP diphosphatase activity
J4N37_10300	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J4N37_10310	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J4N37_10315	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J4N37_10320	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J4N37_10320	COG0131	Imidazoleglycerol-phosphate dehydratase
J4N37_10330	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J4N37_10345	COG1757	Na H antiporter
J4N37_10355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N37_10365	COG0482	sulfurtransferase activity
J4N37_10375	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J4N37_10395	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J4N37_10410	COG0300	oxidoreductase activity
J4N37_10435	COG2226	methyltransferase
J4N37_10455	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J4N37_10475	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J4N37_10485	COG1674	ftsk spoiiie
J4N37_10495	COG0686	Belongs to the AlaDH PNT family
J4N37_10505	COG0583	DNA-binding transcription factor activity
J4N37_10520	COG4166	transmembrane transport
J4N37_10530	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
J4N37_10535	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
J4N37_10545	COG0539	negative regulation of cytoplasmic translation
J4N37_10555	COG0616	signal peptide processing
J4N37_10560	COG1028	Short-chain dehydrogenase reductase Sdr
J4N37_10580	COG0835	chemotaxis
J4N37_10580	COG0784	Response regulator, receiver
J4N37_10585	COG1940	carbohydrate kinase activity
J4N37_10590	COG0469	pyruvate kinase activity
J4N37_10595	COG4667	esterase of the alpha-beta hydrolase superfamily
J4N37_10610	COG0733	neurotransmitter:sodium symporter activity
J4N37_10625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4N37_10625	COG1263	PTS System
J4N37_10630	COG0084	hydrolase, TatD family'
J4N37_10645	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J4N37_10675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J4N37_10690	COG1399	metal-binding, possibly nucleic acid-binding protein
J4N37_10695	COG0424	maF-like protein
J4N37_10700	COG0564	pseudouridine synthase activity
J4N37_10710	COG1530	ribonuclease E activity
J4N37_10715	COG0659	secondary active sulfate transmembrane transporter activity
J4N37_10720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J4N37_10725	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
J4N37_10740	COG0489	protein tyrosine kinase activity
J4N37_10755	COG2186	Transcriptional regulator
J4N37_10760	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J4N37_10765	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
J4N37_10770	COG0653	protein targeting
J4N37_10775	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4N37_10780	COG3706	GGDEF domain
J4N37_10785	COG0366	Alpha amylase catalytic
J4N37_10790	COG1122	ATPase activity
J4N37_10795	COG4120	Belongs to the binding-protein-dependent transport system permease family
J4N37_10815	COG0280	phosphate acetyltransferase
J4N37_10815	COG0857	belongs to the CobB CobQ family
J4N37_10820	COG3174	membrane
J4N37_10825	COG0435	Glutathione S-transferase
J4N37_10835	COG0444	Belongs to the ABC transporter superfamily
J4N37_10840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N37_10845	COG0601	transmembrane transport
J4N37_10855	COG0314	molybdopterin synthase activity
J4N37_10860	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J4N37_10870	COG0521	Mo-molybdopterin cofactor biosynthetic process
J4N37_10875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J4N37_10880	COG0391	Required for morphogenesis under gluconeogenic growth conditions
J4N37_10885	COG2198	Histidine kinase
J4N37_10890	COG2204	response regulator
J4N37_10895	COG0556	nucleotide-excision repair
J4N37_10905	COG4657	Part of a membrane complex involved in electron transport
J4N37_10915	COG4656	Part of a membrane complex involved in electron transport
J4N37_10920	COG4658	electron transport chain
J4N37_10925	COG4659	FMN binding
J4N37_10930	COG4660	Part of a membrane complex involved in electron transport
J4N37_10935	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J4N37_10940	COG0346	lactoylglutathione lyase activity
J4N37_10950	COG2885	chlorophyll binding
J4N37_10960	COG2056	Na+-H+ antiporter family
J4N37_10970	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J4N37_10990	COG1454	alcohol dehydrogenase
J4N37_10990	COG1012	belongs to the aldehyde dehydrogenase family
J4N37_10995	COG2095	MarC family integral membrane protein
J4N37_11000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N37_11005	COG2165	general secretion pathway protein
J4N37_11010	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J4N37_11015	COG1757	Na H antiporter
J4N37_11040	COG3083	sulfuric ester hydrolase activity
J4N37_11050	COG2214	Heat shock protein DnaJ domain protein
J4N37_11060	COG0443	Heat shock 70 kDa protein
J4N37_11065	COG0123	including yeast histone deacetylase and acetoin utilization protein
J4N37_11080	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4N37_11085	COG0778	Nitroreductase
J4N37_11090	COG1902	pentaerythritol trinitrate reductase activity
J4N37_11090	COG0446	pyridine nucleotide-disulphide oxidoreductase
J4N37_11095	COG0616	signal peptide processing
J4N37_11100	COG0252	asparaginase activity
J4N37_11105	COG3139	Protein of unknown function (DUF1315)
J4N37_11115	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N37_11120	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J4N37_11145	COG2226	methyltransferase
J4N37_11160	COG1785	Belongs to the alkaline phosphatase family
J4N37_11180	COG0668	transmembrane transport
J4N37_11185	COG2261	transglycosylase associated protein
J4N37_11195	COG3501	Rhs element vgr protein
J4N37_11255	COG2964	Protein conserved in bacteria
J4N37_11265	COG0251	oxidation-reduction process
J4N37_11270	COG0814	amino acid
J4N37_11275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J4N37_11280	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J4N37_11290	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J4N37_11300	COG2832	Protein of unknown function (DUF454)
J4N37_11305	COG0745	RESPONSE REGULATOR receiver
J4N37_11310	COG0583	DNA-binding transcription factor activity
J4N37_11315	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J4N37_11320	COG1286	toxin biosynthetic process
J4N37_11325	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
J4N37_11330	COG0285	dihydrofolate synthase activity
J4N37_11350	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J4N37_11355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4N37_11360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J4N37_11380	COG3101	peptidyl-lysine hydroxylation
J4N37_11385	COG2860	membrane
J4N37_11390	COG1028	Short-chain dehydrogenase reductase Sdr
J4N37_11395	COG0583	DNA-binding transcription factor activity
J4N37_11405	COG2890	protein-(glutamine-N5) methyltransferase activity
J4N37_11410	COG2840	Smr protein MutS2
J4N37_11415	COG2062	phosphohistidine phosphatase, SixA
J4N37_11435	COG0183	Belongs to the thiolase family
J4N37_11450	COG2067	long-chain fatty acid transport protein
J4N37_11460	COG2853	Lipoprotein
J4N37_11475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4N37_11480	COG1138	Cytochrome C-type biogenesis protein
J4N37_11495	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4N37_11500	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J4N37_11505	COG4133	protoheme IX ABC transporter activity
J4N37_11515	COG0835	chemotaxis
J4N37_11525	COG1192	Involved in chromosome partitioning
J4N37_11530	COG2201	protein-glutamate methylesterase activity
J4N37_11535	COG0784	Response regulator, receiver
J4N37_11535	COG2198	Histidine kinase
J4N37_11535	COG0643	Histidine kinase
J4N37_11540	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
J4N37_11580	COG1987	bacterial-type flagellum assembly
J4N37_11605	COG1580	Controls the rotational direction of flagella during chemotaxis
J4N37_11630	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J4N37_11640	COG1677	Flagellar hook-basal body complex protein FliE
J4N37_11660	COG1516	flagellar protein fliS
J4N37_11670	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J4N37_11675	COG1334	flagellar protein FlaG
J4N37_11680	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N37_11685	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N37_11690	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N37_11695	COG2211	Major facilitator Superfamily
J4N37_11700	COG1486	melibiose metabolic process
J4N37_11705	COG2169	Transcriptional regulator
J4N37_11710	COG2837	iron assimilation
J4N37_11735	COG1393	Belongs to the ArsC family
J4N37_11755	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
J4N37_11760	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J4N37_11765	COG2716	regulation of RNA biosynthetic process
J4N37_11770	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J4N37_11785	COG4783	chaperone-mediated protein folding
J4N37_11790	COG1393	Belongs to the ArsC family
J4N37_11810	COG2233	PERMEase
J4N37_11815	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J4N37_11820	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J4N37_11825	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J4N37_11830	COG0121	glutamine amidotransferase
J4N37_11835	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J4N37_11840	COG1960	acyl-CoA dehydrogenase activity
J4N37_11855	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J4N37_11865	COG2226	methyltransferase
J4N37_11870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4N37_11875	COG0741	lytic transglycosylase activity
J4N37_11875	COG1388	LysM domain
J4N37_11890	COG0347	Belongs to the P(II) protein family
J4N37_11910	COG0587	DNA-directed DNA polymerase activity
J4N37_11925	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4N37_11935	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4N37_11940	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
J4N37_11950	COG0750	zinc metalloprotease
J4N37_11960	COG0575	Belongs to the CDS family
J4N37_11965	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J4N37_11990	COG0024	Methionine aminopeptidase
J4N37_12005	COG0564	pseudouridine synthase activity
J4N37_12010	COG3098	single-species biofilm formation
J4N37_12045	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J4N37_12060	COG1720	tRNA m6t6A37 methyltransferase activity
J4N37_12085	COG0733	neurotransmitter:sodium symporter activity
J4N37_12095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4N37_12100	COG0514	ATP-dependent DNA helicase (RecQ)
J4N37_12105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J4N37_12120	COG1477	protein flavinylation
J4N37_12130	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J4N37_12155	COG0271	Belongs to the BolA IbaG family
J4N37_12185	COG1595	DNA-templated transcription, initiation
J4N37_12200	COG3248	Nucleoside-binding outer membrane protein
J4N37_12205	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J4N37_12210	COG0693	protein deglycase activity
J4N37_12215	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J4N37_12220	COG2166	iron-sulfur cluster assembly
J4N37_12225	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J4N37_12230	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
J4N37_12240	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J4N37_12240	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J4N37_12255	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J4N37_12260	COG1074	ATP-dependent DNA helicase activity
J4N37_12265	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J4N37_12270	COG3083	sulfuric ester hydrolase activity
J4N37_12285	COG3141	response to X-ray
J4N37_12300	COG2171	N-acyltransferase activity
J4N37_12305	COG0584	glycerophosphoryl diester phosphodiesterase
J4N37_12310	COG2271	Major facilitator Superfamily
J4N37_12315	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J4N37_12325	COG1349	DNA-binding transcription factor activity
J4N37_12330	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J4N37_12335	COG3064	Membrane
J4N37_12360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4N37_12365	COG1609	Transcriptional regulator
J4N37_12370	COG2017	converts alpha-aldose to the beta-anomer
J4N37_12380	COG1085	galactose-1-phosphate uridylyltransferase
J4N37_12385	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4N37_12390	COG0768	penicillin binding
J4N37_12395	COG1609	Transcriptional regulator
J4N37_12400	COG3250	beta-galactosidase activity
J4N37_12405	COG2731	YhcH YjgK YiaL family protein
J4N37_12410	COG0531	amino acid
J4N37_12415	COG0583	DNA-binding transcription factor activity
J4N37_12475	COG4964	Belongs to the GSP D family
J4N37_12500	COG2169	Transcriptional regulator
J4N37_12505	COG1022	Amp-dependent synthetase and ligase
J4N37_12515	COG0583	DNA-binding transcription factor activity
J4N37_12520	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J4N37_12525	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J4N37_12535	COG0560	Phosphoserine phosphatase
J4N37_12545	COG0813	purine-nucleoside phosphorylase activity
J4N37_12555	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
J4N37_12560	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
J4N37_12565	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4N37_12570	COG0084	hydrolase, TatD family'
J4N37_12580	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
J4N37_12585	COG3706	GGDEF domain
J4N37_12605	COG3153	acetyltransferase
J4N37_12610	COG3154	lipid carrier protein
J4N37_12620	COG0826	peptidase U32
J4N37_12625	COG0826	peptidase U32
J4N37_12630	COG0534	Mate efflux family protein
J4N37_12650	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J4N37_12670	COG0195	Participates in both transcription termination and antitermination
J4N37_12690	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J4N37_12700	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J4N37_12705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J4N37_12715	COG1534	Rna-binding protein
J4N37_12720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4N37_12725	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J4N37_12730	COG2027	D-alanyl-D-alanine carboxypeptidase
J4N37_12745	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J4N37_12750	COG0739	heme binding
J4N37_12755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N37_12775	COG0628	permease
J4N37_12785	COG2205	protein histidine kinase activity
J4N37_12785	COG0784	Response regulator, receiver
J4N37_12790	COG0747	negative chemotaxis
J4N37_12800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N37_12805	COG0444	Belongs to the ABC transporter superfamily
J4N37_12810	COG4608	Belongs to the ABC transporter superfamily
J4N37_12820	COG2971	BadF BadG BcrA BcrD
J4N37_12835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4N37_12840	COG3842	ATPase activity
J4N37_12850	COG1840	ABC-type Fe3 transport system, periplasmic component
J4N37_12855	COG0004	ammonium transporteR
J4N37_12870	COG1049	propionate catabolic process, 2-methylcitrate cycle
J4N37_12875	COG1752	Esterase of the alpha-beta hydrolase superfamily
J4N37_12880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4N37_12885	COG1643	Atp-dependent helicase
J4N37_12900	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J4N37_12910	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J4N37_12925	COG1560	Kdo2-lipid A biosynthetic process
J4N37_12930	COG0842	Transport permease protein
J4N37_12935	COG1131	(ABC) transporter
J4N37_12940	COG0659	secondary active sulfate transmembrane transporter activity
J4N37_12945	COG0288	reversible hydration of carbon dioxide
J4N37_12965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N37_12970	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4N37_12975	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
J4N37_12980	COG2186	Transcriptional regulator
J4N37_12995	COG4969	Belongs to the N-Me-Phe pilin family
J4N37_13000	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4N37_13005	COG1459	type II secretion system
J4N37_13015	COG0237	dephospho-CoA kinase activity
J4N37_13020	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
J4N37_13025	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
J4N37_13045	COG0228	four-way junction DNA binding
J4N37_13050	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J4N37_13055	COG4137	Cytochrome C assembly protein
J4N37_13060	COG4536	flavin adenine dinucleotide binding
J4N37_13080	COG0612	Peptidase, M16
J4N37_13085	COG1238	metal cluster binding
J4N37_13095	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
J4N37_13100	COG5016	pyruvate
J4N37_13100	COG0511	ligase activity, forming carbon-carbon bonds
J4N37_13105	COG3630	sodium ion export across plasma membrane
J4N37_13170	COG0527	aspartate kinase activity
J4N37_13185	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J4N37_13190	COG1546	Belongs to the CinA family
J4N37_13200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J4N37_13230	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J4N37_13240	COG0148	phosphopyruvate hydratase activity
J4N37_13250	COG3956	TIGRFAM MazG family protein
J4N37_13255	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J4N37_13275	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J4N37_13280	COG1381	Involved in DNA repair and RecF pathway recombination
J4N37_13285	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J4N37_13305	COG3086	response to oxidative stress
J4N37_13320	COG1595	DNA-templated transcription, initiation
J4N37_13325	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J4N37_13330	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J4N37_13350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N37_13355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4N37_13360	COG3079	Belongs to the UPF0149 family
J4N37_13365	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
J4N37_13375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J4N37_13385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4N37_13395	COG0583	DNA-binding transcription factor activity
J4N37_13410	COG0668	transmembrane transport
J4N37_13415	COG0191	fructose-bisphosphate aldolase activity
J4N37_13435	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J4N37_13455	COG2356	endonuclease I
J4N37_13460	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J4N37_13465	COG0189	ligase activity
J4N37_13470	COG1678	Uncharacterized ACR, COG1678
J4N37_13475	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J4N37_13490	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J4N37_13495	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J4N37_13500	COG0762	integral membrane protein
J4N37_13515	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J4N37_13520	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J4N37_13620	COG1012	belongs to the aldehyde dehydrogenase family
J4N37_13660	COG1609	Transcriptional regulator
J4N37_13670	COG1486	melibiose metabolic process
J4N37_13675	COG1447	Phosphotransferase system cellobiose-specific component IIA
J4N37_13685	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4N37_13700	COG1028	Short-chain dehydrogenase reductase Sdr
J4N37_13710	COG0795	lipopolysaccharide-transporting ATPase activity
J4N37_13715	COG0795	lipopolysaccharide-transporting ATPase activity
J4N37_13725	COG2927	DNA polymerase III (CHI subunit)
J4N37_13730	COG0525	valine-tRNA ligase activity
J4N37_13740	COG0456	acetyltransferase
J4N37_13780	COG0251	oxidation-reduction process
J4N37_13785	COG0204	Acyl-transferase
J4N37_13795	COG5007	Belongs to the BolA IbaG family
J4N37_13805	COG2854	intermembrane phospholipid transfer
J4N37_13810	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J4N37_13815	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J4N37_13820	COG1127	ABC transporter
J4N37_13830	COG0517	IMP dehydrogenase activity
J4N37_13830	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J4N37_13840	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J4N37_13845	COG1137	ATPase activity
J4N37_13855	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J4N37_13860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N37_13870	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N37_13875	COG2239	Acts as a magnesium transporter
J4N37_13880	COG0312	modulator of DNA gyrase
J4N37_13890	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J4N37_13895	COG0564	pseudouridine synthase activity
J4N37_13910	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J4N37_13915	COG0312	modulator of DNA gyrase
J4N37_13920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J4N37_13925	COG3164	Protein of unknown function
J4N37_13935	COG0424	maF-like protein
J4N37_13940	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
J4N37_13945	COG1792	Involved in formation and maintenance of cell shape
J4N37_13950	COG1077	Cell shape determining protein MreB Mrl
J4N37_13985	COG2165	general secretion pathway protein
J4N37_13995	COG1459	type II secretion system
J4N37_14000	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4N37_14010	COG3267	Type II secretory pathway component ExeA
J4N37_14010	COG3409	Peptidoglycan-binding domain 1 protein
J4N37_14035	COG2199	diguanylate cyclase activity
J4N37_14035	COG2200	EAL domain
J4N37_14040	COG0629	single-stranded DNA binding
J4N37_14055	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J4N37_14065	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J4N37_14070	COG0527	aspartate kinase activity
J4N37_14075	COG1410	methionine synthase
J4N37_14075	COG0646	methionine synthase
J4N37_14145	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J4N37_14165	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4N37_14170	COG0735	belongs to the Fur family
J4N37_14185	COG0432	Pfam Uncharacterised protein family UPF0047
J4N37_14195	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J4N37_14200	COG0305	Participates in initiation and elongation during chromosome replication
J4N37_14220	COG2965	DNA replication, synthesis of RNA primer
J4N37_14230	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J4N37_14235	COG0338	D12 class N6 adenine-specific DNA methyltransferase
J4N37_14280	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J4N37_14290	COG0678	peroxiredoxin activity
J4N37_14290	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J4N37_14300	COG0165	Argininosuccinate lyase
J4N37_14300	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J4N37_14315	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J4N37_14325	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
J4N37_14335	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J4N37_14340	COG0460	homoserine dehydrogenase
J4N37_14340	COG0527	aspartate kinase activity
J4N37_14345	COG0626	cystathionine gamma-synthase activity
J4N37_14355	COG0281	malic enzyme
J4N37_14365	COG2906	2 iron, 2 sulfur cluster binding
J4N37_14375	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J4N37_14390	COG2168	tRNA wobble position uridine thiolation
J4N37_14395	COG2923	Belongs to the DsrF TusC family
J4N37_14400	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
J4N37_14405	COG2964	Protein conserved in bacteria
J4N37_14410	COG0545	Peptidyl-prolyl cis-trans isomerase
J4N37_14425	COG1446	asparaginase
J4N37_14430	COG1047	Peptidyl-prolyl cis-trans
J4N37_14445	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N37_14450	COG0488	(ABC) transporter
J4N37_14460	COG0429	hydrolase of the alpha beta-hydrolase fold
J4N37_14465	COG3089	Belongs to the UPF0270 family
J4N37_14470	COG3954	Phosphoribulokinase
J4N37_14475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4N37_14495	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J4N37_14505	COG0512	Glutamine amidotransferase of anthranilate synthase
J4N37_14520	COG0546	phosphoglycolate phosphatase activity
J4N37_14525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4N37_14530	COG0557	exoribonuclease II activity
J4N37_14540	COG1017	nitric oxide dioxygenase activity
J4N37_14540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4N37_14545	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
J4N37_14550	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J4N37_14555	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
J4N37_14560	COG0330	HflC and HflK could
J4N37_14565	COG0330	HflC and HflK could
J4N37_14570	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J4N37_14585	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J4N37_14590	COG0860	N-Acetylmuramoyl-L-alanine amidase
J4N37_14595	COG0802	atpase or kinase
J4N37_14600	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J4N37_14670	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
J4N37_14675	COG1162	GTPase activity
J4N37_14685	COG0471	metal ion transport
J4N37_14700	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J4N37_14705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4N37_14720	COG1045	serine acetyltransferase
J4N37_14725	COG4942	peptidase
J4N37_14745	COG1053	succinate dehydrogenase
J4N37_14750	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J4N37_14775	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J4N37_14780	COG1509	lysine 2,3-aminomutase activity
J4N37_14785	COG1285	pathogenesis
J4N37_14805	COG0534	Mate efflux family protein
J4N37_14815	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J4N37_14820	COG3678	ATP-independent chaperone mediated protein folding
J4N37_14825	COG0745	RESPONSE REGULATOR receiver
J4N37_14830	COG2205	protein histidine kinase activity
J4N37_14840	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J4N37_14845	COG3030	protein affecting phage T7 exclusion by the F plasmid
J4N37_14850	COG1027	Aspartate ammonia-lyase
J4N37_14855	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J4N37_14860	COG4232	protein-disulfide reductase activity
J4N37_14870	COG2095	MarC family integral membrane protein
J4N37_14880	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N37_14900	COG2205	protein histidine kinase activity
J4N37_14900	COG0784	Response regulator, receiver
J4N37_14900	COG2198	Histidine kinase
J4N37_14905	COG2814	Major facilitator Superfamily
J4N37_14920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J4N37_14925	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J4N37_14930	COG0511	ligase activity, forming carbon-carbon bonds
J4N37_14935	COG0439	Biotin carboxylase
J4N37_14945	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4N37_14950	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
J4N37_14955	COG5001	Diguanylate cyclase
J4N37_14955	COG3300	MHYT domain
J4N37_15000	COG1982	Orn Lys Arg decarboxylase major
J4N37_15005	COG0531	amino acid
J4N37_15010	COG3710	Transcriptional regulator
J4N37_15015	COG0789	Transcriptional regulator
J4N37_15025	COG0138	bifunctional purine biosynthesis protein purh
J4N37_15030	COG0151	Belongs to the GarS family
J4N37_15045	COG1253	flavin adenine dinucleotide binding
J4N37_15050	COG3068	Protein conserved in bacteria
J4N37_15060	COG1573	uracil-dna glycosylase
J4N37_15070	COG2816	NAD+ diphosphatase activity
J4N37_15075	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
J4N37_15095	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J4N37_15110	COG0250	Participates in transcription elongation, termination and antitermination
J4N37_15115	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J4N37_15155	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J4N37_15165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4N37_15280	COG1309	transcriptional regulator
J4N37_15285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4N37_15290	COG0534	Mate efflux family protein
J4N37_15305	COG2937	Belongs to the GPAT DAPAT family
J4N37_15315	COG3161	chorismate lyase activity
J4N37_15320	COG1580	Controls the rotational direction of flagella during chemotaxis
J4N37_15325	COG0705	Rhomboid family
J4N37_15330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4N37_15340	COG2177	Part of the ABC transporter FtsEX involved in
J4N37_15345	COG2884	Cell division ATP-binding protein ftsE
J4N37_15350	COG0552	protein localization to endoplasmic reticulum
J4N37_15355	COG0742	ribosomal rna small subunit methyltransferase
J4N37_15365	COG2095	MarC family integral membrane protein
J4N37_15410	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J4N37_15415	COG0640	Transcriptional regulator
J4N37_15420	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J4N37_15425	COG1280	lysine exporter protein (LysE YggA)
J4N37_15430	COG2267	carboxylic ester hydrolase activity
J4N37_15435	COG0561	phosphatase activity
J4N37_15450	COG3148	PFAM DTW domain containing protein
J4N37_15455	COG3287	FIST C domain
J4N37_15455	COG2199	diguanylate cyclase activity
J4N37_15455	COG2200	EAL domain
J4N37_15460	COG1011	Hydrolase
J4N37_15480	COG0019	diaminopimelate decarboxylase activity
J4N37_15495	COG3072	Adenylate cyclase
J4N37_15505	COG1587	Uroporphyrinogen-III synthase
J4N37_15510	COG2959	enzyme of heme biosynthesis
J4N37_15515	COG3071	HemY protein
J4N37_15555	COG0633	Ferredoxin
J4N37_15560	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
J4N37_15575	COG3118	belongs to the thioredoxin family
J4N37_15590	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J4N37_15600	COG0514	ATP-dependent DNA helicase (RecQ)
J4N37_15605	COG2962	Rard protein
J4N37_15615	COG1280	lysine exporter protein (LysE YggA)
J4N37_15620	COG0405	Gamma-glutamyltransferase
J4N37_15625	COG0210	DNA helicase
J4N37_15635	COG3220	belongs to the UPF0276 family
J4N37_15655	COG2814	Major facilitator Superfamily
J4N37_15665	COG0006	proline dipeptidase activity
J4N37_15665	COG0006	proline dipeptidase activity
J4N37_15680	COG2104	thiamine diphosphate biosynthetic process
J4N37_15685	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J4N37_15705	COG2132	Multicopper oxidase
J4N37_15745	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J4N37_15770	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J4N37_15775	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J4N37_15780	COG0551	DNA topoisomerase type I activity
J4N37_15790	COG0758	DNA mediated transformation
J4N37_15810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J4N37_15810	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J4N37_15815	COG0569	domain protein
J4N37_15820	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4N37_15830	COG1272	protein, Hemolysin III
J4N37_15835	COG4326	sporulation control protein
J4N37_15845	COG3084	Protein conserved in bacteria
J4N37_15855	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J4N37_15860	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4N37_15865	COG0204	Acyl-transferase
J4N37_15875	COG3706	GGDEF domain
J4N37_15880	COG0606	chelatase, subunit chli
J4N37_15890	COG3978	acetolactate synthase activity
J4N37_15895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J4N37_15900	COG0129	dihydroxy-acid dehydratase activity
J4N37_15910	COG0583	DNA-binding transcription factor activity
J4N37_15915	COG2814	Major facilitator Superfamily
J4N37_15920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N37_15925	COG0765	amino acid transport
J4N37_15935	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J4N37_15945	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J4N37_15975	COG3312	ion transport
J4N37_15980	COG1475	DNA binding
J4N37_15985	COG1192	Involved in chromosome partitioning
J4N37_16000	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J4N37_16030	COG1126	abc transporter atp-binding protein
J4N37_16070	COG0023	Translation Initiation Factor
J4N37_16085	COG3266	domain, Protein
J4N37_16090	COG1042	CoA-binding domain protein
J4N37_16090	COG0045	succinate-CoA ligase (ADP-forming) activity
J4N37_16090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N37_16095	COG0583	DNA-binding transcription factor activity
J4N37_16110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4N37_16115	COG3447	MASE1 domain protein
J4N37_16115	COG5001	Diguanylate cyclase
J4N37_16115	COG5002	protein histidine kinase activity
J4N37_16125	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
J4N37_16130	COG1984	allophanate hydrolase subunit 2
J4N37_16140	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
J4N37_16145	COG4181	ATPase activity
J4N37_16155	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J4N37_16160	COG3300	MHYT domain
J4N37_16160	COG5001	Diguanylate cyclase
J4N37_16170	COG0484	heat shock protein binding
J4N37_16205	COG2050	protein possibly involved in aromatic compounds catabolism
J4N37_16220	COG2067	long-chain fatty acid transport protein
J4N37_16225	COG2267	carboxylic ester hydrolase activity
J4N37_16240	COG1410	methionine synthase
J4N37_16240	COG0646	methionine synthase
J4N37_16255	COG0737	Belongs to the 5'-nucleotidase family
J4N37_16260	COG3593	DNA synthesis involved in DNA repair
J4N37_16270	COG0583	DNA-binding transcription factor activity
J4N37_16275	COG2116	formate transmembrane transporter activity
J4N37_16285	COG3038	cytochrome b561
J4N37_16300	COG4943	cyclic-guanylate-specific phosphodiesterase activity
J4N37_16305	COG0513	Belongs to the DEAD box helicase family
J4N37_16310	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
J4N37_16315	COG0840	transmembrane signaling receptor activity
J4N37_16320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N37_16325	COG0784	Response regulator, receiver
J4N37_16325	COG3437	response regulator, receiver
J4N37_16340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N37_16350	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J4N37_16360	COG2207	Transcriptional regulator
J4N37_16365	COG1979	alcohol dehydrogenase
J4N37_16390	COG2271	Major facilitator Superfamily
J4N37_16395	COG0469	pyruvate kinase activity
J4N37_16400	COG1126	abc transporter atp-binding protein
J4N37_16405	COG0765	amino acid transport
J4N37_16410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N37_16415	COG0765	amino acid transport
J4N37_16420	COG2200	EAL domain
J4N37_16420	COG2203	Gaf domain
J4N37_16420	COG2199	diguanylate cyclase activity
J4N37_16435	COG1609	Transcriptional regulator
J4N37_16440	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N37_16440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N37_16445	COG1105	Belongs to the carbohydrate kinase PfkB family
J4N37_16450	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
J4N37_16450	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N37_16450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N37_16465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N37_16470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N37_16480	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J4N37_16490	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J4N37_16495	COG0509	glycine decarboxylation via glycine cleavage system
J4N37_16520	COG1028	Short-chain dehydrogenase reductase Sdr
J4N37_16530	COG2814	Major facilitator Superfamily
J4N37_16555	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J4N37_16560	COG0583	DNA-binding transcription factor activity
J4N37_16585	COG1733	regulation of RNA biosynthetic process
J4N37_16595	COG1132	(ABC) transporter
J4N37_16630	COG3594	Acyltransferase
J4N37_16755	COG0583	DNA-binding transcription factor activity
J4N37_16770	COG3005	denitrification pathway
J4N37_16785	COG1999	signal sequence binding
J4N37_16790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4N37_16805	COG0628	permease
J4N37_16825	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
J4N37_16840	COG0739	heme binding
J4N37_16845	COG1414	Transcriptional regulator
J4N37_16855	COG1902	pentaerythritol trinitrate reductase activity
J4N37_16880	COG0346	lactoylglutathione lyase activity
J4N37_16885	COG1902	pentaerythritol trinitrate reductase activity
J4N37_16895	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J4N37_16895	COG2755	lipolytic protein G-D-S-L family
J4N37_16905	COG5642	Protein of unknown function (DUF2384)
J4N37_16920	COG1234	tRNA 3'-trailer cleavage
J4N37_16980	COG2962	Rard protein
J4N37_16990	COG0784	Response regulator, receiver
J4N37_16990	COG0835	chemotaxis
J4N37_17005	COG5002	protein histidine kinase activity
J4N37_17005	COG3447	MASE1 domain protein
J4N37_17005	COG5001	Diguanylate cyclase
J4N37_17010	COG1475	DNA binding
J4N37_17015	COG3969	phosphoadenosine phosphosulfate
J4N37_17065	COG2197	response regulator
J4N37_17070	COG3300	MHYT domain
J4N37_17070	COG5001	Diguanylate cyclase
J4N37_17075	COG2205	protein histidine kinase activity
J4N37_17075	COG0784	Response regulator, receiver
J4N37_17080	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J4N37_17105	COG3069	C4-dicarboxylate transmembrane transporter activity
J4N37_17110	COG1704	LemA family
J4N37_17115	COG0501	Belongs to the peptidase M48B family
J4N37_17140	COG0641	radical SAM
J4N37_17160	COG3111	PFAM Bacterial OB fold (BOF) protein
J4N37_17165	COG1597	lipid kinase activity
J4N37_17170	COG0583	DNA-binding transcription factor activity
J4N37_17205	COG0714	Associated with various cellular activities
J4N37_17210	COG0641	radical SAM
J4N37_17215	COG3119	arylsulfatase activity
J4N37_17220	COG0583	DNA-binding transcription factor activity
J4N37_17230	COG3119	arylsulfatase activity
J4N37_17235	COG3119	arylsulfatase activity
J4N37_17255	COG0003	Pfam Anion-transporting ATPase
J4N37_17260	COG0745	RESPONSE REGULATOR receiver
J4N37_17280	COG0443	Heat shock 70 kDa protein
J4N37_17295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4N37_17300	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N37_17360	COG1053	succinate dehydrogenase
J4N37_17360	COG0431	NADPH-dependent FMN reductase
J4N37_17360	COG3976	FMN-binding domain protein
J4N37_17370	COG1538	Outer membrane efflux protein
J4N37_17400	COG4160	amino acid transport
J4N37_17405	COG4215	(ABC) transporter
J4N37_17410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N37_17415	COG1126	abc transporter atp-binding protein
J4N37_17450	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N37_17460	COG1012	belongs to the aldehyde dehydrogenase family
J4N37_17475	COG0446	pyridine nucleotide-disulphide oxidoreductase
J4N37_17475	COG1902	pentaerythritol trinitrate reductase activity
J4N37_17485	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J4N37_17490	COG1845	cytochrome c oxidase, subunit III
J4N37_17495	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J4N37_17500	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J4N37_17505	COG1028	Short-chain dehydrogenase reductase Sdr
J4N37_17515	COG1024	Enoyl-CoA hydratase
J4N37_17520	COG1024	Enoyl-CoA hydratase
J4N37_17535	COG0183	Belongs to the thiolase family
J4N37_17545	COG1960	acyl-CoA dehydrogenase activity
J4N37_17550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J4N37_17555	COG1024	Enoyl-CoA hydratase
J4N37_17585	COG3278	Belongs to the heme-copper respiratory oxidase family
J4N37_17600	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J4N37_17605	COG0513	Belongs to the DEAD box helicase family
J4N37_17610	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
J4N37_17625	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J4N37_17640	COG1119	ATPase activity
J4N37_17645	COG2200	EAL domain
J4N37_17665	COG0513	Belongs to the DEAD box helicase family
J4N37_17675	COG0523	cobalamin synthesis protein
J4N37_17710	COG3530	Putative quorum-sensing-regulated virulence factor
J4N37_17740	COG3186	Phenylalanine-4-hydroxylase
J4N37_17745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J4N37_17750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4N37_17780	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
J4N37_17785	COG1454	alcohol dehydrogenase
J4N37_17790	COG2133	pyrroloquinoline quinone binding
J4N37_17795	COG1619	proteins homologs of microcin C7 resistance protein MccF
J4N37_17820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J4N37_17820	COG2205	protein histidine kinase activity
J4N37_17825	COG2203	Gaf domain
J4N37_17825	COG5001	Diguanylate cyclase
J4N37_17825	COG4251	negative regulation of phosphorylation
J4N37_17825	COG3706	GGDEF domain
J4N37_17840	COG0330	HflC and HflK could
J4N37_17860	COG0517	IMP dehydrogenase activity
J4N37_17860	COG4175	Glycine betaine
J4N37_17865	COG4176	ABC-type proline glycine betaine transport system permease component
J4N37_17905	COG0076	glutamate decarboxylase activity
J4N37_17920	COG0402	S-adenosylhomocysteine deaminase activity
J4N37_17925	COG2165	general secretion pathway protein
J4N37_17940	COG3738	Protein conserved in bacteria
J4N37_17955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N37_17985	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J4N37_17985	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J4N37_18000	COG2197	response regulator
J4N37_18005	COG3850	Histidine kinase
J4N37_18010	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J4N37_18020	COG0243	molybdopterin cofactor binding
J4N37_18030	COG3005	denitrification pathway
J4N37_18050	COG0183	Belongs to the thiolase family
J4N37_18060	COG1280	lysine exporter protein (LysE YggA)
J4N37_18070	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N37_18075	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4N37_18120	COG1879	ABC-type sugar transport system periplasmic component
J4N37_18125	COG2827	Endonuclease containing a URI domain
J4N37_18140	COG2926	Belongs to the UPF0265 family
J4N37_18150	COG0673	inositol 2-dehydrogenase activity
J4N37_18155	COG2205	protein histidine kinase activity
J4N37_18155	COG5002	protein histidine kinase activity
J4N37_18155	COG0784	Response regulator, receiver
J4N37_18190	COG0531	amino acid
J4N37_18205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N37_18220	COG2205	protein histidine kinase activity
J4N37_18225	COG0745	RESPONSE REGULATOR receiver
J4N37_18245	COG1566	PFAM secretion protein HlyD family protein
J4N37_18250	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J4N37_18255	COG2239	Acts as a magnesium transporter
J4N37_18260	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J4N37_18265	COG0402	S-adenosylhomocysteine deaminase activity
J4N37_18275	COG1418	mRNA catabolic process
J4N37_18290	COG2814	Major facilitator Superfamily
J4N37_18300	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J4N37_18320	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4N37_18335	COG4221	oxidoreductase activity
J4N37_18345	COG0745	RESPONSE REGULATOR receiver
J4N37_18350	COG2205	protein histidine kinase activity
J4N37_18360	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J4N37_18365	COG2194	sulfuric ester hydrolase activity
J4N37_18380	COG1335	isochorismatase
J4N37_18390	COG2814	Major facilitator Superfamily
J4N37_18410	COG0583	DNA-binding transcription factor activity
J4N37_18415	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N37_18430	COG0583	DNA-binding transcription factor activity
J4N37_18505	COG4989	oxidoreductase activity
J4N37_18525	COG1733	regulation of RNA biosynthetic process
J4N37_18540	COG0798	PFAM Bile acid sodium symporter
J4N37_18555	COG1881	PFAM PEBP family protein
J4N37_18565	COG1301	dicarboxylic acid transport
J4N37_18570	COG1252	NADH dehydrogenase
J4N37_18585	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J4N37_18600	COG5001	Diguanylate cyclase
J4N37_18600	COG4251	negative regulation of phosphorylation
J4N37_18600	COG3706	GGDEF domain
J4N37_18600	COG2203	Gaf domain
J4N37_18605	COG1028	Short-chain dehydrogenase reductase Sdr
J4N37_18610	COG0110	maltose O-acetyltransferase activity
J4N37_18615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N37_18635	COG2197	response regulator
J4N37_18645	COG0840	transmembrane signaling receptor activity
J4N37_18650	COG0714	Associated with various cellular activities
J4N37_18670	COG2304	oxidoreductase activity
J4N37_18685	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4N37_18690	COG0581	inorganic phosphate transmembrane transporter activity
J4N37_18695	COG0573	inorganic phosphate transmembrane transporter activity
J4N37_18705	COG0840	transmembrane signaling receptor activity
J4N37_18725	COG4771	TonB-dependent receptor
J4N37_18730	COG1770	oligopeptidase
J4N37_18735	COG0513	Belongs to the DEAD box helicase family
J4N37_18745	COG1376	ErfK ybiS ycfS ynhG family protein
J4N37_18745	COG1388	LysM domain
J4N37_18750	COG0415	Belongs to the DNA photolyase family
J4N37_18755	COG0789	Transcriptional regulator
J4N37_18760	COG3272	Protein of unknown function (DUF1722)
J4N37_18765	COG0813	purine-nucleoside phosphorylase activity
J4N37_18795	COG1566	PFAM secretion protein HlyD family protein
J4N37_18805	COG1122	ATPase activity
J4N37_18820	COG0348	domain, Protein
J4N37_18825	COG0437	4 iron, 4 sulfur cluster binding
J4N37_18830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N37_18850	COG0840	transmembrane signaling receptor activity
J4N37_18855	COG0840	transmembrane signaling receptor activity
J4N37_18860	COG1067	ATP-dependent peptidase activity
J4N37_18870	COG4172	Belongs to the ABC transporter superfamily
J4N37_18875	COG1505	serine-type exopeptidase activity
J4N37_18880	COG0583	DNA-binding transcription factor activity
J4N37_18885	COG1620	l-lactate permease
J4N37_18890	COG1304	FMN binding
J4N37_18905	COG0668	transmembrane transport
J4N37_18925	COG1063	alcohol dehydrogenase
J4N37_18930	COG0156	8-amino-7-oxononanoate synthase activity
J4N37_18940	COG0745	RESPONSE REGULATOR receiver
J4N37_18965	COG0346	lactoylglutathione lyase activity
J4N37_19015	COG2200	EAL domain
J4N37_19075	COG1987	bacterial-type flagellum assembly
J4N37_19100	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J4N37_19105	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J4N37_19125	COG1580	Controls the rotational direction of flagella during chemotaxis
J4N37_19130	COG1191	sigma factor activity
J4N37_19135	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J4N37_19140	COG1360	Flagellar Motor Protein
J4N37_19175	COG2226	methyltransferase
J4N37_19190	COG3710	Transcriptional regulator
J4N37_19195	COG1253	flavin adenine dinucleotide binding
J4N37_19235	COG1256	bacterial-type flagellum assembly
J4N37_19235	COG4786	Flagellar basal body rod
J4N37_19245	COG1706	bacterial-type flagellum-dependent cell motility
J4N37_19250	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J4N37_19255	COG4786	Flagellar basal body rod
J4N37_19260	COG4787	bacterial-type flagellum-dependent cell motility
J4N37_19265	COG1749	Flagellar hook protein flgE
J4N37_19270	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
J4N37_19275	COG1558	bacterial-type flagellum-dependent cell motility
J4N37_19280	COG1815	bacterial-type flagellum-dependent cell motility
J4N37_19300	COG1388	LysM domain
J4N37_19300	COG0741	lytic transglycosylase activity
J4N37_19325	COG1760	l-serine dehydratase
J4N37_19330	COG3104	oligopeptide transport
J4N37_19355	COG0583	DNA-binding transcription factor activity
J4N37_19360	COG2885	chlorophyll binding
J4N37_19360	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
J4N37_19365	COG2866	Carboxypeptidase
J4N37_19370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J4N37_19395	COG3842	ATPase activity
J4N37_19400	COG1840	ABC-type Fe3 transport system, periplasmic component
J4N37_19410	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J4N37_19430	COG3240	lipase activity
J4N37_19460	COG1011	Hydrolase
J4N37_19505	COG1765	OsmC-like protein
J4N37_19510	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N37_19510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N37_19525	COG3046	protein related to deoxyribodipyrimidine photolyase
J4N37_19530	COG0415	Belongs to the DNA photolyase family
J4N37_19535	COG3706	GGDEF domain
J4N37_19555	COG3706	GGDEF domain
J4N37_19575	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J4N37_19580	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J4N37_19590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4N37_19600	COG4628	conserved protein (DUF2132)
J4N37_19605	COG0583	DNA-binding transcription factor activity
J4N37_19630	COG1686	Belongs to the peptidase S11 family
J4N37_19645	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J4N37_19665	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4N37_19670	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4N37_19685	COG0415	Belongs to the DNA photolyase family
J4N37_19695	COG4667	esterase of the alpha-beta hydrolase superfamily
J4N37_19700	COG0840	transmembrane signaling receptor activity
J4N37_19705	COG2095	MarC family integral membrane protein
J4N37_19730	COG0583	DNA-binding transcription factor activity
J4N37_19760	COG1301	dicarboxylic acid transport
J4N37_19770	COG3339	Conserved Protein
J4N37_19775	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J4N37_19780	COG0700	Nucleoside recognition
J4N37_19785	COG3366	ferrous iron transmembrane transporter activity
J4N37_19800	COG0366	Alpha amylase catalytic
J4N37_19805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4N37_19810	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J4N37_19815	COG1640	4-alpha-glucanotransferase
J4N37_19820	COG0058	SHG alpha-glucan phosphorylase activity
J4N37_19840	COG1999	signal sequence binding
J4N37_19855	COG1162	GTPase activity
J4N37_19860	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
J4N37_19875	COG0531	amino acid
J4N37_19880	COG1982	Orn Lys Arg decarboxylase major
J4N37_19900	COG2356	endonuclease I
J4N37_19930	COG2199	diguanylate cyclase activity
J4N37_19930	COG2203	Gaf domain
J4N37_19940	COG1760	l-serine dehydratase
J4N37_19965	COG1609	Transcriptional regulator
J4N37_19975	COG2814	Major facilitator Superfamily
J4N37_19980	COG3214	Protein conserved in bacteria
J4N37_19990	COG4771	TonB-dependent receptor
J4N37_19995	COG0583	DNA-binding transcription factor activity
J4N37_20000	COG4607	ABC-type enterochelin transport system periplasmic component
J4N37_20005	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N37_20010	COG4605	iron ion homeostasis
J4N37_20015	COG4604	ABC transporter, ATP-binding protein
J4N37_20040	COG0739	heme binding
J4N37_20055	COG0612	Peptidase, M16
J4N37_20060	COG0840	transmembrane signaling receptor activity
J4N37_20065	COG1120	ATPase activity
J4N37_20070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N37_20075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N37_20080	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
J4N37_20085	COG4772	TonB-dependent receptor
J4N37_20110	COG4264	IucA IucC family
J4N37_20115	COG0019	diaminopimelate decarboxylase activity
J4N37_20120	COG0826	peptidase U32
J4N37_20140	COG1355	regulation of microtubule-based process
J4N37_20150	COG1136	(ABC) transporter
J4N37_20155	COG0577	efflux transmembrane transporter activity
J4N37_20180	COG1764	response to oxidative stress
J4N37_20185	COG1846	Transcriptional regulator
J4N37_20195	COG3634	alkyl hydroperoxide reductase activity
J4N37_20225	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
J4N37_20235	COG1522	sequence-specific DNA binding
J4N37_20250	COG2258	MOSC domain
J4N37_20260	COG3713	MltA-interacting MipA family protein
J4N37_20265	COG0513	Belongs to the DEAD box helicase family
J4N37_20270	COG1595	DNA-templated transcription, initiation
J4N37_20280	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J4N37_20285	COG1312	Catalyzes the dehydration of D-mannonate
J4N37_20290	COG2186	Transcriptional regulator
J4N37_20300	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J4N37_20310	COG0246	Mannitol dehydrogenase
J4N37_20315	COG1904	glucuronate isomerase
J4N37_20320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N37_20325	COG0800	Aldolase
J4N37_20345	COG1132	(ABC) transporter
J4N37_20350	COG0259	pyridoxamine-phosphate oxidase activity
J4N37_20360	COG2204	response regulator
J4N37_20420	COG1444	tRNA N-acetyltransferase activity
J4N37_20445	COG4608	Belongs to the ABC transporter superfamily
J4N37_20450	COG0444	Belongs to the ABC transporter superfamily
J4N37_20460	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J4N37_20460	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
J4N37_20485	COG0772	Belongs to the SEDS family
J4N37_20500	COG1566	PFAM secretion protein HlyD family protein
J4N37_20505	COG0583	DNA-binding transcription factor activity
J4N37_20515	COG1136	(ABC) transporter
J4N37_20535	COG3275	phosphorelay sensor kinase activity
J4N37_20540	COG3279	Response regulator of the LytR AlgR family
J4N37_20550	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J4N37_20575	COG0786	glutamate:sodium symporter activity
J4N37_20590	COG1131	(ABC) transporter
J4N37_20595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N37_20600	COG0786	glutamate:sodium symporter activity
J4N37_20635	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
J4N37_20640	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J4N37_20650	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J4N37_20690	COG3123	guanosine phosphorylase activity
J4N37_20700	COG5001	Diguanylate cyclase
J4N37_20710	COG1609	Transcriptional regulator
J4N37_20725	COG0395	ABC-type sugar transport system, permease component
J4N37_20730	COG2723	6-phospho-beta-galactosidase activity
J4N37_20735	COG3842	ATPase activity
J4N37_20740	COG1609	Transcriptional regulator
J4N37_20750	COG0747	negative chemotaxis
J4N37_20760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4N37_20765	COG0444	Belongs to the ABC transporter superfamily
J4N37_20770	COG4608	Belongs to the ABC transporter superfamily
J4N37_20780	COG1609	Transcriptional regulator
J4N37_20800	COG1472	Belongs to the glycosyl hydrolase 3 family
J4N37_20805	COG0534	Mate efflux family protein
J4N37_20835	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4N37_20875	COG0406	alpha-ribazole phosphatase activity
J4N37_20895	COG0564	pseudouridine synthase activity
J4N37_20900	COG0561	phosphatase activity
J4N37_20920	COG3152	Membrane
J4N37_20935	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
J4N37_20940	COG2162	N-hydroxyarylamine O-acetyltransferase activity
J4N37_20950	COG0583	DNA-binding transcription factor activity
J4N37_20955	COG2375	cellular response to nickel ion
J4N37_20985	COG2076	Multidrug Resistance protein
J4N37_21000	COG1357	PFAM Pentapeptide repeats (8 copies)
J4N37_21005	COG3047	cAMP biosynthetic process
J4N37_21010	COG2358	TRAP transporter, solute receptor (TAXI family
J4N37_21025	COG2814	Major facilitator Superfamily
J4N37_21040	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
J4N37_21040	COG3408	Glycogen debranching enzyme
J4N37_21095	COG0546	phosphoglycolate phosphatase activity
J4N37_21120	COG1929	Belongs to the glycerate kinase type-1 family
J4N37_21125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N37_21170	COG0456	acetyltransferase
J4N37_21190	COG1028	Short-chain dehydrogenase reductase Sdr
J4N37_21200	COG0671	phosphoesterase, PA-phosphatase related
J4N37_21215	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J4N37_21220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J4N37_21225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J4N37_21230	COG1116	anion transmembrane transporter activity
J4N37_21235	COG0351	phosphomethylpyrimidine kinase
J4N37_21240	COG0312	modulator of DNA gyrase
J4N37_21245	COG0312	modulator of DNA gyrase
J4N37_21305	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J4N37_21315	COG0584	glycerophosphoryl diester phosphodiesterase
J4N37_21320	COG0039	L-malate dehydrogenase activity
J4N37_21325	COG0745	RESPONSE REGULATOR receiver
J4N37_21345	COG0811	peptide transport
J4N37_21350	COG0811	peptide transport
J4N37_21355	COG0848	biopolymer transport protein
J4N37_21400	COG0803	Belongs to the bacterial solute-binding protein 9 family
J4N37_21405	COG1121	(ABC) transporter
J4N37_21410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J4N37_21425	COG1770	oligopeptidase
J4N37_21430	COG2814	Major facilitator Superfamily
J4N37_21435	COG0010	Belongs to the arginase family
J4N37_21440	COG1166	arginine decarboxylase activity
J4N37_21450	COG4067	protein conserved in archaea
J4N37_21450	COG0189	ligase activity
J4N37_21455	COG0189	ligase activity
J4N37_21475	COG0583	DNA-binding transcription factor activity
J4N37_21510	COG4191	Histidine kinase
J4N37_21530	COG1114	Component of the transport system for branched-chain amino acids
J4N37_21545	COG0579	oxidoreductase
J4N37_21550	COG3179	chitinase
J4N37_21570	COG3033	Beta-eliminating lyase
J4N37_21585	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J4N37_21590	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
J4N37_21595	COG0628	permease
J4N37_21635	COG2988	succinylglutamate desuccinylase activity
J4N37_21650	COG2814	Major facilitator Superfamily
J4N37_21660	COG0454	-acetyltransferase
J4N37_21675	COG2199	diguanylate cyclase activity
J4N37_21680	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J4N37_21685	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J4N37_21690	COG1882	Formate acetyltransferase
J4N37_21700	COG1733	regulation of RNA biosynthetic process
J4N37_21705	COG0840	transmembrane signaling receptor activity
J4N37_21735	COG0384	phenazine biosynthesis protein PhzF
J4N37_21740	COG0346	lactoylglutathione lyase activity
J4N37_21745	COG0488	(ABC) transporter
J4N37_21750	COG4628	conserved protein (DUF2132)
J4N37_21755	COG0583	DNA-binding transcription factor activity
J4N37_21760	COG0431	NADPH-dependent FMN reductase
J4N37_21765	COG0435	Glutathione S-transferase
J4N37_21770	COG0488	(ABC) transporter
J4N37_21785	COG0583	DNA-binding transcription factor activity
J4N37_21795	COG3226	Transcriptional regulator
J4N37_21815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4N37_21820	COG1280	lysine exporter protein (LysE YggA)
J4N37_21835	COG2207	Transcriptional regulator
J4N37_21840	COG2382	esterase
J4N37_21845	COG4771	TonB-dependent receptor
J4N37_21850	COG2207	Transcriptional regulator
J4N37_21860	COG4302	ethanolamine ammonia-lyase activity
J4N37_21865	COG0531	amino acid
J4N37_21870	COG2070	2-Nitropropane dioxygenase
J4N37_21875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N37_21885	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N37_21885	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4N37_21890	COG0346	lactoylglutathione lyase activity
J4N37_21895	COG1349	DNA-binding transcription factor activity
J4N37_21915	COG1335	isochorismatase
J4N37_21965	COG0583	DNA-binding transcription factor activity
J4N37_21990	COG3448	diguanylate cyclase activity
J4N37_21990	COG4175	Glycine betaine
J4N37_21995	COG4176	ABC-type proline glycine betaine transport system permease component
J4N37_22005	COG1342	Belongs to the UPF0251 family
J4N37_22035	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J4N37_22040	COG4948	Mandelate Racemase Muconate Lactonizing
J4N37_22080	COG3710	Transcriptional regulator
J4N37_22125	COG2264	protein methyltransferase activity
J4N37_22130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4N37_22140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N37_22155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N37_22195	COG0318	PFAM AMP-dependent synthetase and ligase
J4N37_22200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N37_22225	COG0786	glutamate:sodium symporter activity
J4N37_22240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N37_22245	COG0583	DNA-binding transcription factor activity
J4N37_22260	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J4N37_22265	COG2197	response regulator
J4N37_22280	COG0574	Belongs to the PEP-utilizing enzyme family
J4N37_22280	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J4N37_22295	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J4N37_22300	COG0583	DNA-binding transcription factor activity
J4N37_22325	COG3122	Protein conserved in bacteria
J4N37_22340	COG1902	pentaerythritol trinitrate reductase activity
J4N37_22350	COG2814	Major facilitator Superfamily
J4N37_22355	COG1028	Short-chain dehydrogenase reductase Sdr
J4N37_22380	COG0583	DNA-binding transcription factor activity
J4N37_22390	COG0583	DNA-binding transcription factor activity
J4N37_22400	COG0513	Belongs to the DEAD box helicase family
J4N37_22425	COG0095	Lipoate-protein ligase
J4N37_22440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4N37_22445	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J4N37_22445	COG2207	Transcriptional regulator
J4N37_22450	COG0583	DNA-binding transcription factor activity
J4N37_22460	COG1028	Short-chain dehydrogenase reductase Sdr
J4N37_22480	COG3746	phosphate-selective porin O and P
J4N37_22505	COG1028	Short-chain dehydrogenase reductase Sdr
J4N37_22520	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J4N37_22530	COG0625	glutathione transferase activity
J4N37_22540	COG2249	NAD(P)H dehydrogenase (quinone) activity
J4N37_22545	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4N37_22550	COG1686	Belongs to the peptidase S11 family
J4N37_22555	COG3706	GGDEF domain
J4N37_22565	COG2226	methyltransferase
J4N37_22595	COG3706	GGDEF domain
J4N37_22600	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J4N37_22615	COG1278	Cold shock
J4N37_22620	COG1741	Belongs to the pirin family
J4N37_22625	COG4667	esterase of the alpha-beta hydrolase superfamily
J4N37_22635	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J4N37_22645	COG0523	cobalamin synthesis protein
J4N37_22685	COG3842	ATPase activity
J4N37_22690	COG0395	ABC-type sugar transport system, permease component
J4N37_22695	COG1175	transmembrane transport
J4N37_22720	COG0589	response to stress
J4N37_22740	COG1720	tRNA m6t6A37 methyltransferase activity
J4N37_22745	COG0488	(ABC) transporter
J4N37_22750	COG1505	serine-type exopeptidase activity
J4N37_22755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J4N37_22765	COG1858	cytochrome C peroxidase
J4N37_22780	COG0494	nUDIX hydrolase
J4N37_22795	COG0456	acetyltransferase
J4N37_22800	COG3321	synthase
J4N37_22800	COG0604	alcohol dehydrogenase
J4N37_22800	COG1028	Short-chain dehydrogenase reductase Sdr
J4N37_22840	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4N37_22860	COG3383	formate dehydrogenase (NAD+) activity
J4N37_22875	COG0842	Transport permease protein
J4N37_22880	COG1131	(ABC) transporter
J4N37_22905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N37_22940	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N37_22940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4N37_22940	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N37_22945	COG2207	Transcriptional regulator
J4N37_22955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N37_22960	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J4N37_22965	COG0583	DNA-binding transcription factor activity
J4N37_22975	COG2084	Dehydrogenase
J4N37_22980	COG0753	catalase activity
J4N37_22990	COG2130	NADP-dependent
J4N37_22995	COG1309	transcriptional regulator
J4N37_23025	COG0438	transferase activity, transferring glycosyl groups
J4N37_23030	COG3206	protein involved in exopolysaccharide biosynthesis
J4N37_23030	COG0489	protein tyrosine kinase activity
J4N37_23045	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J4N37_23050	COG3842	ATPase activity
J4N37_23060	COG1175	transmembrane transport
J4N37_23065	COG3833	ABC-type maltose transport systems, permease component
J4N37_23095	COG2354	Protein conserved in bacteria
J4N37_23105	COG0401	homolog of Blt101
J4N37_23110	COG3217	Mosc domain protein beta barrel domain protein
J4N37_23110	COG0633	Ferredoxin
J4N37_23110	COG0633	Ferredoxin
J4N37_23110	COG3217	Mosc domain protein beta barrel domain protein
J4N37_23120	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J4N37_23160	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
J4N37_23165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N37_23175	COG0848	biopolymer transport protein
J4N37_23180	COG0811	peptide transport
J4N37_23185	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
J4N37_23195	COG3721	Heme iron utilization protein
J4N37_23200	COG0748	coenzyme F420 binding
J4N37_23215	COG0784	Response regulator, receiver
J4N37_23215	COG0835	chemotaxis
J4N37_23220	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4N37_23225	COG0366	Alpha amylase catalytic
J4N37_23230	COG0840	transmembrane signaling receptor activity
J4N37_23235	COG0814	amino acid
J4N37_23245	COG3314	Sporulation integral membrane protein YlbJ
J4N37_23265	COG0739	heme binding
J4N37_23270	COG5001	Diguanylate cyclase
J4N37_23275	COG0583	DNA-binding transcription factor activity
J4N37_23280	COG2814	Major facilitator Superfamily
J4N37_23295	COG0697	spore germination
J4N37_23300	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J4N37_23310	COG0179	Fumarylacetoacetate (FAA) hydrolase
J4N37_23330	COG1280	lysine exporter protein (LysE YggA)
J4N37_23340	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4N37_23355	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
J4N37_23380	COG1612	heme a metabolic process
J4N37_23395	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4N37_23400	COG2814	Major facilitator Superfamily
J4N37_23405	COG0840	transmembrane signaling receptor activity
J4N37_23410	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J4N37_23435	COG2897	thiosulfate sulfurtransferase activity
J4N37_23465	COG1914	H( )-stimulated, divalent metal cation uptake system
J4N37_23490	COG4989	oxidoreductase activity
J4N37_23505	COG2195	Cleaves the N-terminal amino acid of tripeptides
J4N37_23525	COG0840	transmembrane signaling receptor activity
J4N37_23535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4N37_23540	COG0545	Peptidyl-prolyl cis-trans isomerase
J4N37_23550	COG2885	chlorophyll binding
J4N37_23570	COG1278	Cold shock
J4N37_23575	COG3036	rescue of stalled ribosome
J4N37_23585	COG2203	Gaf domain
J4N37_23585	COG2199	diguanylate cyclase activity
J4N37_23605	COG1136	(ABC) transporter
J4N37_23605	COG0577	efflux transmembrane transporter activity
J4N37_23620	COG0783	Belongs to the Dps family
J4N37_23685	COG3829	transcription factor binding
J4N37_23745	COG3501	Rhs element vgr protein
J4N37_23835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4N37_23850	COG2208	phosphoserine phosphatase activity
J4N37_23855	COG1366	Belongs to the anti-sigma-factor antagonist family
J4N37_23860	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J4N37_23940	COG1051	belongs to the nudix hydrolase family
J4N37_23945	COG1794	racemase activity, acting on amino acids and derivatives
J4N37_23955	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J4N37_23960	COG5001	Diguanylate cyclase
J4N37_23970	COG1129	ABC transporter
J4N37_23975	COG1172	Belongs to the binding-protein-dependent transport system permease family
J4N37_23980	COG1879	ABC-type sugar transport system periplasmic component
J4N37_23985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4N37_23990	COG1609	Transcriptional regulator
J4N37_23995	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
J4N37_24010	COG4607	ABC-type enterochelin transport system periplasmic component
J4N37_24015	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4N37_24020	COG4605	iron ion homeostasis
J4N37_24025	COG4604	ABC transporter, ATP-binding protein
J4N37_24030	COG0789	Transcriptional regulator
J4N37_24040	COG4206	TonB-dependent receptor
J4N37_24065	COG1289	transmembrane transporter activity
J4N37_24070	COG0210	DNA helicase
J4N37_24075	COG1803	Methylglyoxal synthase
J4N37_24080	COG1879	ABC-type sugar transport system periplasmic component
J4N37_24085	COG2205	protein histidine kinase activity
J4N37_24085	COG2198	Histidine kinase
J4N37_24085	COG0784	Response regulator, receiver
J4N37_24105	COG0515	serine threonine protein kinase
J4N37_24105	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J4N37_24115	COG1785	Belongs to the alkaline phosphatase family
J4N37_24135	COG3706	GGDEF domain
J4N37_24145	COG0814	amino acid
J4N37_24150	COG5002	protein histidine kinase activity
J4N37_24150	COG5001	Diguanylate cyclase
J4N37_24160	COG0243	molybdopterin cofactor binding
J4N37_24170	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J4N37_24185	COG1116	anion transmembrane transporter activity
J4N37_24185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J4N37_24190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J4N37_24195	COG1116	anion transmembrane transporter activity
J4N37_24200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4N37_24200	COG2146	nitrite reductase [NAD(P)H] activity
J4N37_24255	COG0515	serine threonine protein kinase
J4N37_24255	COG2815	serine threonine protein kinase
J4N37_24290	COG0631	protein serine/threonine phosphatase activity
J4N37_24360	COG0420	3'-5' exonuclease activity
J4N37_24365	COG0419	ATPase involved in DNA repair
J4N37_24375	COG3469	chitinase activity
J4N37_24405	COG3040	lipid binding
J4N37_24415	COG2814	Major facilitator Superfamily
J4N37_24425	COG1288	antiporter activity
J4N37_24435	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
J4N37_24450	COG2425	protein containing a von Willebrand factor type A (vWA) domain
J4N37_24465	COG0583	DNA-binding transcription factor activity
J4N37_24470	COG0277	FAD linked oxidase domain protein
J4N37_24515	COG0840	transmembrane signaling receptor activity
J4N37_24565	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4N37_24575	COG2116	formate transmembrane transporter activity
J4N37_24595	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J4N37_24600	COG0840	transmembrane signaling receptor activity
J4N37_24635	COG3118	belongs to the thioredoxin family
J4N37_24640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J4N37_24665	COG1566	PFAM secretion protein HlyD family protein
J4N37_24675	COG0628	permease
J4N37_24685	COG1482	cell wall glycoprotein biosynthetic process
J4N37_24690	COG2271	Major facilitator Superfamily
J4N37_24695	COG3851	Histidine kinase
J4N37_24700	COG2197	response regulator
J4N37_24760	COG1328	CTP reductase activity
J4N37_24765	COG0602	queuosine metabolic process
J4N37_24770	COG0534	Mate efflux family protein
J4N37_24785	COG4067	protein conserved in archaea
J4N37_24785	COG0189	ligase activity
J4N37_24795	COG3111	PFAM Bacterial OB fold (BOF) protein
J4N37_24805	COG0725	ABC transporter, periplasmic molybdate-binding protein
J4N37_24810	COG4149	molybdate abc transporter
J4N37_24815	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
J4N37_24825	COG2203	Gaf domain
J4N37_24825	COG5001	Diguanylate cyclase
J4N37_24825	COG4251	negative regulation of phosphorylation
J4N37_24825	COG3706	GGDEF domain
J4N37_24855	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J4N37_24860	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
J4N37_24870	COG0745	RESPONSE REGULATOR receiver
J4N37_24885	COG3140	Belongs to the UPF0181 family