locus-tag	class	description
J8Z27_00010	COG0592	DNA-directed DNA polymerase activity
J8Z27_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J8Z27_00020	COG0187	DNA topoisomerase II activity
J8Z27_00030	COG3977	Valine--pyruvate aminotransferase
J8Z27_00040	COG0752	glycyl-tRNA synthetase alpha subunit
J8Z27_00045	COG2119	membrane
J8Z27_00055	COG0425	Belongs to the sulfur carrier protein TusA family
J8Z27_00070	COG0604	alcohol dehydrogenase
J8Z27_00080	COG0129	dihydroxy-acid dehydratase activity
J8Z27_00085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J8Z27_00090	COG3978	acetolactate synthase activity
J8Z27_00100	COG0606	chelatase, subunit chli
J8Z27_00135	COG0464	growth
J8Z27_00140	COG1061	Type III restriction enzyme res subunit
J8Z27_00205	COG0204	Acyl-transferase
J8Z27_00210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J8Z27_00215	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J8Z27_00225	COG3084	Protein conserved in bacteria
J8Z27_00235	COG4326	sporulation control protein
J8Z27_00240	COG1272	protein, Hemolysin III
J8Z27_00250	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J8Z27_00255	COG0569	domain protein
J8Z27_00260	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J8Z27_00260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J8Z27_00275	COG0758	DNA mediated transformation
J8Z27_00280	COG2922	Belongs to the Smg family
J8Z27_00285	COG0551	DNA topoisomerase type I activity
J8Z27_00290	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J8Z27_00295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J8Z27_00305	COG0408	coproporphyrinogen oxidase activity
J8Z27_00320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J8Z27_00385	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J8Z27_00390	COG3300	MHYT domain
J8Z27_00390	COG5001	Diguanylate cyclase
J8Z27_00400	COG3852	Histidine kinase
J8Z27_00405	COG0174	glutamine synthetase
J8Z27_00410	COG1217	gtp-binding protein TYPA
J8Z27_00425	COG1295	ribonuclease BN
J8Z27_00430	COG1490	D-aminoacyl-tRNA deacylase activity
J8Z27_00435	COG0456	acetyltransferase
J8Z27_00445	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
J8Z27_00450	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
J8Z27_00455	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J8Z27_00460	COG3031	protein transport across the cell outer membrane
J8Z27_00470	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J8Z27_00475	COG1459	type II secretion system
J8Z27_00480	COG2165	general secretion pathway protein
J8Z27_00485	COG2165	general secretion pathway protein
J8Z27_00490	COG2165	general secretion pathway protein
J8Z27_00495	COG4795	General secretion pathway protein
J8Z27_00500	COG3156	type II secretion system protein K
J8Z27_00505	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
J8Z27_00510	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
J8Z27_00530	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J8Z27_00540	COG2183	response to ionizing radiation
J8Z27_00555	COG1040	competence protein
J8Z27_00565	COG0494	nUDIX hydrolase
J8Z27_00570	COG1218	3'(2'),5'-bisphosphate nucleotidase
J8Z27_00575	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J8Z27_00580	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J8Z27_00585	COG1561	YicC-like family, N-terminal region
J8Z27_00590	COG2252	PERMEase
J8Z27_00595	COG0194	GDP metabolic process
J8Z27_00600	COG1758	RNA polymerase activity
J8Z27_00605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J8Z27_00610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J8Z27_00615	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J8Z27_00620	COG1560	Kdo2-lipid A biosynthetic process
J8Z27_00625	COG1560	Kdo2-lipid A biosynthetic process
J8Z27_00630	COG1309	transcriptional regulator
J8Z27_00640	COG2003	Belongs to the UPF0758 family
J8Z27_00645	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J8Z27_00665	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
J8Z27_00670	COG0859	PFAM glycosyl transferase family 9
J8Z27_00675	COG0463	Glycosyl transferase, family 2
J8Z27_00680	COG0859	PFAM glycosyl transferase family 9
J8Z27_00685	COG3642	lipopolysaccharide core region biosynthetic process
J8Z27_00735	COG1519	Transferase
J8Z27_00750	COG0859	PFAM glycosyl transferase family 9
J8Z27_00765	COG3307	-O-antigen
J8Z27_00795	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J8Z27_00810	COG1132	(ABC) transporter
J8Z27_00815	COG1086	Polysaccharide biosynthesis protein
J8Z27_00820	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J8Z27_00825	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J8Z27_00830	COG2089	acid synthase
J8Z27_00850	COG1083	cytidylyl-transferase
J8Z27_00885	COG1215	transferase activity, transferring glycosyl groups
J8Z27_00900	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J8Z27_00905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J8Z27_00910	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
J8Z27_00910	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
J8Z27_00915	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J8Z27_00955	COG1494	fructose-1,6-bisphosphatase
J8Z27_00960	COG3074	FtsZ-dependent cytokinesis
J8Z27_00965	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J8Z27_00970	COG0527	aspartate kinase activity
J8Z27_00970	COG0460	homoserine dehydrogenase
J8Z27_00975	COG0626	cystathionine gamma-synthase activity
J8Z27_00980	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
J8Z27_00985	COG0281	malic enzyme
J8Z27_00995	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J8Z27_01000	COG1609	Transcriptional regulator
J8Z27_01005	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J8Z27_01010	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
J8Z27_01030	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
J8Z27_01035	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J8Z27_01040	COG1053	succinate dehydrogenase
J8Z27_01045	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
J8Z27_01050	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J8Z27_01085	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J8Z27_01100	COG1045	serine acetyltransferase
J8Z27_01105	COG1695	Transcriptional regulator
J8Z27_01110	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
J8Z27_01115	COG1573	uracil-dna glycosylase
J8Z27_01120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J8Z27_01130	COG1253	flavin adenine dinucleotide binding
J8Z27_01145	COG0151	Belongs to the GarS family
J8Z27_01150	COG0138	bifunctional purine biosynthesis protein purh
J8Z27_01155	COG0789	Transcriptional regulator
J8Z27_01160	COG2199	diguanylate cyclase activity
J8Z27_01165	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
J8Z27_01170	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J8Z27_01175	COG2264	protein methyltransferase activity
J8Z27_01180	COG0439	Biotin carboxylase
J8Z27_01185	COG0511	ligase activity, forming carbon-carbon bonds
J8Z27_01190	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J8Z27_01195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J8Z27_01210	COG2814	Major facilitator Superfamily
J8Z27_01215	COG0784	Response regulator, receiver
J8Z27_01215	COG2205	protein histidine kinase activity
J8Z27_01220	COG1072	(Pantothenic acid kinase))
J8Z27_01245	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J8Z27_01250	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J8Z27_01255	COG0250	Participates in transcription elongation, termination and antitermination
J8Z27_01270	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J8Z27_01280	COG0085	RNA polymerase activity
J8Z27_01285	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J8Z27_01290	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J8Z27_01295	COG1027	Aspartate ammonia-lyase
J8Z27_01370	COG0512	Glutamine amidotransferase of anthranilate synthase
J8Z27_01375	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J8Z27_01385	COG1012	belongs to the aldehyde dehydrogenase family
J8Z27_01395	COG0688	phosphatidylethanolamine metabolic process
J8Z27_01400	COG1162	GTPase activity
J8Z27_01455	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J8Z27_01460	COG0802	atpase or kinase
J8Z27_01465	COG0860	N-Acetylmuramoyl-L-alanine amidase
J8Z27_01470	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J8Z27_01485	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J8Z27_01490	COG0330	HflC and HflK could
J8Z27_01495	COG0330	HflC and HflK could
J8Z27_01500	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
J8Z27_01505	COG2900	Belongs to the SlyX family
J8Z27_01515	COG0545	Peptidyl-prolyl cis-trans isomerase
J8Z27_01520	COG2964	Protein conserved in bacteria
J8Z27_01525	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
J8Z27_01530	COG2923	Belongs to the DsrF TusC family
J8Z27_01535	COG2168	tRNA wobble position uridine thiolation
J8Z27_01545	COG0049	tRNA binding
J8Z27_01550	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J8Z27_01555	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J8Z27_01560	COG2906	2 iron, 2 sulfur cluster binding
J8Z27_01570	COG0360	Binds together with S18 to 16S ribosomal RNA
J8Z27_01590	COG0305	Participates in initiation and elongation during chromosome replication
J8Z27_01595	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J8Z27_01600	COG0432	Pfam Uncharacterised protein family UPF0047
J8Z27_01625	COG1136	(ABC) transporter
J8Z27_01640	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
J8Z27_01650	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J8Z27_01655	COG0729	surface antigen
J8Z27_01660	COG2911	Protein conserved in bacteria
J8Z27_01665	COG2105	PFAM AIG2 family protein
J8Z27_01670	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J8Z27_01680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J8Z27_01685	COG0163	prenyltransferase activity
J8Z27_01690	COG4143	(ABC) transporter
J8Z27_01695	COG1178	ABC-type Fe3 transport system permease component
J8Z27_01700	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
J8Z27_01710	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J8Z27_01725	COG0629	single-stranded DNA binding
J8Z27_01730	COG2200	EAL domain
J8Z27_01730	COG2199	diguanylate cyclase activity
J8Z27_01755	COG3409	Peptidoglycan-binding domain 1 protein
J8Z27_01755	COG3267	Type II secretory pathway component ExeA
J8Z27_01765	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J8Z27_01770	COG1459	type II secretion system
J8Z27_01780	COG2165	general secretion pathway protein
J8Z27_01785	COG2165	general secretion pathway protein
J8Z27_01815	COG1077	Cell shape determining protein MreB Mrl
J8Z27_01820	COG1792	Involved in formation and maintenance of cell shape
J8Z27_01825	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
J8Z27_01830	COG0424	maF-like protein
J8Z27_01840	COG3164	Protein of unknown function
J8Z27_01845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J8Z27_01850	COG0312	modulator of DNA gyrase
J8Z27_01905	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
J8Z27_01915	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J8Z27_01920	COG2066	Belongs to the glutaminase family
J8Z27_01925	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J8Z27_01930	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J8Z27_01965	COG0762	integral membrane protein
J8Z27_01970	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J8Z27_01975	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J8Z27_01990	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J8Z27_01995	COG1678	Uncharacterized ACR, COG1678
J8Z27_02000	COG0189	ligase activity
J8Z27_02005	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J8Z27_02010	COG2356	endonuclease I
J8Z27_02015	COG3091	SprT-like family
J8Z27_02025	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J8Z27_02030	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J8Z27_02035	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J8Z27_02045	COG0191	fructose-bisphosphate aldolase activity
J8Z27_02050	COG0668	transmembrane transport
J8Z27_02065	COG0583	DNA-binding transcription factor activity
J8Z27_02075	COG3706	GGDEF domain
J8Z27_02085	COG0469	pyruvate kinase activity
J8Z27_02090	COG1349	DNA-binding transcription factor activity
J8Z27_02095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J8Z27_02110	COG0473	3-isopropylmalate dehydrogenase activity
J8Z27_02115	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J8Z27_02130	COG0583	DNA-binding transcription factor activity
J8Z27_02135	COG1022	Amp-dependent synthetase and ligase
J8Z27_02140	COG0028	Belongs to the TPP enzyme family
J8Z27_02145	COG0440	acetolactate synthase activity
J8Z27_02150	COG0584	glycerophosphoryl diester phosphodiesterase
J8Z27_02155	COG2271	Major facilitator Superfamily
J8Z27_02160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J8Z27_02170	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J8Z27_02185	COG3079	Belongs to the UPF0149 family
J8Z27_02190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J8Z27_02195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J8Z27_02210	COG0354	folic acid binding
J8Z27_02215	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J8Z27_02220	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J8Z27_02225	COG1595	DNA-templated transcription, initiation
J8Z27_02235	COG3026	antisigma factor binding
J8Z27_02240	COG3086	response to oxidative stress
J8Z27_02245	COG0481	GTPase activity
J8Z27_02255	COG0571	ribonuclease III activity
J8Z27_02260	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J8Z27_02265	COG1381	Involved in DNA repair and RecF pathway recombination
J8Z27_02270	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J8Z27_02275	COG0736	holo-[acyl-carrier-protein] synthase activity
J8Z27_02280	COG2205	protein histidine kinase activity
J8Z27_02280	COG3437	response regulator, receiver
J8Z27_02280	COG3850	Histidine kinase
J8Z27_02280	COG4999	Histidine kinase
J8Z27_02285	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J8Z27_02290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J8Z27_02295	COG3956	TIGRFAM MazG family protein
J8Z27_02305	COG0148	phosphopyruvate hydratase activity
J8Z27_02310	COG0617	tRNA 3'-terminal CCA addition
J8Z27_02315	COG3267	Type II secretory pathway component ExeA
J8Z27_02315	COG3409	Peptidoglycan-binding domain 1 protein
J8Z27_02325	COG4991	sh3 domain protein
J8Z27_02330	COG0306	phosphate transporter
J8Z27_02335	COG1392	Phosphate transport regulator
J8Z27_02340	COG3025	triphosphatase activity
J8Z27_02345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J8Z27_02355	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J8Z27_02360	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J8Z27_02360	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J8Z27_02365	COG0745	RESPONSE REGULATOR receiver
J8Z27_02375	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J8Z27_02390	COG0083	homoserine kinase activity
J8Z27_02395	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J8Z27_02400	COG2860	membrane
J8Z27_02415	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J8Z27_02420	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J8Z27_02440	COG0534	Mate efflux family protein
J8Z27_02445	COG2204	response regulator
J8Z27_02455	COG0667	Aldo Keto reductase
J8Z27_02465	COG3066	DNA modification
J8Z27_02470	COG0494	nUDIX hydrolase
J8Z27_02480	COG0730	response to heat
J8Z27_02485	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J8Z27_02490	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J8Z27_02495	COG1283	sodium-dependent phosphate transmembrane transporter activity
J8Z27_02500	COG0583	DNA-binding transcription factor activity
J8Z27_02505	COG0640	Transcriptional regulator
J8Z27_02510	COG0268	Binds directly to 16S ribosomal RNA
J8Z27_02515	COG0728	peptidoglycan biosynthetic process
J8Z27_02520	COG0196	riboflavin kinase activity
J8Z27_02535	COG1047	Peptidyl-prolyl cis-trans
J8Z27_02540	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J8Z27_02545	COG1966	Carbon starvation protein
J8Z27_02555	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
J8Z27_02560	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
J8Z27_02565	COG2971	BadF BadG BcrA BcrD
J8Z27_02575	COG1737	Transcriptional regulator
J8Z27_02585	COG3279	Response regulator of the LytR AlgR family
J8Z27_02590	COG3275	phosphorelay sensor kinase activity
J8Z27_02595	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J8Z27_02600	COG1605	Chorismate mutase
J8Z27_02600	COG0287	Prephenate dehydrogenase
J8Z27_02605	COG0739	heme binding
J8Z27_02615	COG0488	(ABC) transporter
J8Z27_02620	COG0741	lytic transglycosylase activity
J8Z27_02625	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
J8Z27_02630	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
J8Z27_02635	COG5001	Diguanylate cyclase
J8Z27_02640	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J8Z27_02645	COG0077	Prephenate dehydratase
J8Z27_02645	COG1605	Chorismate mutase
J8Z27_02650	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J8Z27_02655	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
J8Z27_02660	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J8Z27_02665	COG0564	pseudouridine synthase activity
J8Z27_02670	COG1496	oxidoreductase activity
J8Z27_02675	COG0542	response to heat
J8Z27_02720	COG0483	inositol monophosphate 1-phosphatase activity
J8Z27_02725	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
J8Z27_02735	COG1104	cysteine desulfurase activity
J8Z27_02740	COG0822	iron-sulfur transferase activity
J8Z27_02755	COG0443	Heat shock 70 kDa protein
J8Z27_02760	COG0633	Ferredoxin
J8Z27_02765	COG2975	iron-sulfur cluster assembly
J8Z27_02780	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J8Z27_02785	COG0583	DNA-binding transcription factor activity
J8Z27_02795	COG0583	DNA-binding transcription factor activity
J8Z27_02800	COG1022	Amp-dependent synthetase and ligase
J8Z27_02805	COG2169	Transcriptional regulator
J8Z27_02835	COG4964	Belongs to the GSP D family
J8Z27_02885	COG2059	Chromate
J8Z27_02890	COG0583	DNA-binding transcription factor activity
J8Z27_02900	COG2169	Transcriptional regulator
J8Z27_02905	COG1486	melibiose metabolic process
J8Z27_02910	COG2211	Major facilitator Superfamily
J8Z27_02920	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J8Z27_02925	COG1085	galactose-1-phosphate uridylyltransferase
J8Z27_02935	COG2017	converts alpha-aldose to the beta-anomer
J8Z27_02940	COG1609	Transcriptional regulator
J8Z27_02950	COG2211	Major facilitator Superfamily
J8Z27_02975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J8Z27_02975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J8Z27_02975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J8Z27_02985	COG2171	N-acyltransferase activity
J8Z27_02990	COG0450	alkyl hydroperoxide reductase
J8Z27_02995	COG0583	DNA-binding transcription factor activity
J8Z27_03000	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J8Z27_03025	COG0517	IMP dehydrogenase activity
J8Z27_03030	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J8Z27_03040	COG1862	Preprotein translocase
J8Z27_03045	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J8Z27_03050	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J8Z27_03070	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J8Z27_03075	COG0826	peptidase U32
J8Z27_03085	COG0745	RESPONSE REGULATOR receiver
J8Z27_03090	COG5002	protein histidine kinase activity
J8Z27_03100	COG0248	Ppx GppA phosphatase
J8Z27_03105	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J8Z27_03115	COG0581	inorganic phosphate transmembrane transporter activity
J8Z27_03120	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J8Z27_03125	COG0704	Plays a role in the regulation of phosphate uptake
J8Z27_03145	COG3141	response to X-ray
J8Z27_03160	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J8Z27_03165	COG1074	ATP-dependent DNA helicase activity
J8Z27_03170	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J8Z27_03190	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
J8Z27_03195	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J8Z27_03200	COG2166	iron-sulfur cluster assembly
J8Z27_03215	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J8Z27_03220	COG0124	histidyl-tRNA synthetase
J8Z27_03225	COG2976	Protein conserved in bacteria
J8Z27_03230	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J8Z27_03235	COG1160	GTP binding
J8Z27_03240	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J8Z27_03255	COG0517	IMP dehydrogenase activity
J8Z27_03255	COG0516	GMP reductase activity
J8Z27_03270	COG1584	GPR1 FUN34 yaaH family protein
J8Z27_03275	COG1115	amino acid carrier protein
J8Z27_03285	COG0583	DNA-binding transcription factor activity
J8Z27_03300	COG0784	Response regulator, receiver
J8Z27_03300	COG0835	chemotaxis
J8Z27_03305	COG0204	Acyl-transferase
J8Z27_03320	COG0527	aspartate kinase activity
J8Z27_03325	COG2203	Gaf domain
J8Z27_03325	COG3706	GGDEF domain
J8Z27_03325	COG4251	negative regulation of phosphorylation
J8Z27_03325	COG5001	Diguanylate cyclase
J8Z27_03330	COG3706	GGDEF domain
J8Z27_03340	COG2239	Acts as a magnesium transporter
J8Z27_03345	COG0189	ligase activity
J8Z27_03345	COG4067	protein conserved in archaea
J8Z27_03350	COG0189	ligase activity
J8Z27_03370	COG2867	negative regulation of translational initiation
J8Z27_03375	COG2914	Belongs to the UPF0125 (RnfH) family
J8Z27_03380	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J8Z27_03385	COG0497	DNA recombination
J8Z27_03390	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J8Z27_03395	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J8Z27_03405	COG0443	Heat shock 70 kDa protein
J8Z27_03440	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J8Z27_03450	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
J8Z27_03455	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J8Z27_03455	COG0047	phosphoribosylformylglycinamidine synthase activity
J8Z27_03480	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J8Z27_03485	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J8Z27_03490	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J8Z27_03495	COG1187	pseudouridine synthase activity
J8Z27_03500	COG2840	Smr protein MutS2
J8Z27_03525	COG3104	oligopeptide transport
J8Z27_03530	COG0367	asparagine synthase
J8Z27_03535	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J8Z27_03535	COG4651	solute:proton antiporter activity
J8Z27_03540	COG1846	Transcriptional regulator
J8Z27_03540	COG1940	carbohydrate kinase activity
J8Z27_03545	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J8Z27_03550	COG1263	PTS System
J8Z27_03550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J8Z27_03550	COG2190	(PTS) system
J8Z27_03585	COG0330	HflC and HflK could
J8Z27_03590	COG3118	belongs to the thioredoxin family
J8Z27_03595	COG0300	oxidoreductase activity
J8Z27_03600	COG1090	epimerase
J8Z27_03625	COG0622	Phosphoesterase
J8Z27_03645	COG3710	Transcriptional regulator
J8Z27_03650	COG0326	Molecular chaperone. Has ATPase activity
J8Z27_03660	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J8Z27_03670	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J8Z27_03675	COG1611	Belongs to the LOG family
J8Z27_03690	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J8Z27_03690	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J8Z27_03700	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
J8Z27_03715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J8Z27_03720	COG1393	Belongs to the ArsC family
J8Z27_03745	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
J8Z27_03755	COG0437	4 iron, 4 sulfur cluster binding
J8Z27_03760	COG3301	Polysulphide reductase, NrfD
J8Z27_03765	COG1138	Cytochrome C-type biogenesis protein
J8Z27_03770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J8Z27_03775	COG4235	cytochrome complex assembly
J8Z27_03775	COG3088	subunit of a heme lyase
J8Z27_03785	COG2837	iron assimilation
J8Z27_03790	COG2027	D-alanyl-D-alanine carboxypeptidase
J8Z27_03800	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J8Z27_03805	COG0739	heme binding
J8Z27_03820	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J8Z27_03830	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J8Z27_03840	COG1516	flagellar protein fliS
J8Z27_03860	COG1677	Flagellar hook-basal body complex protein FliE
J8Z27_03870	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J8Z27_03920	COG1987	bacterial-type flagellum assembly
J8Z27_03925	COG1684	flagellar biosynthetic protein fliR
J8Z27_03940	COG2890	protein-(glutamine-N5) methyltransferase activity
J8Z27_03945	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J8Z27_03955	COG2860	membrane
J8Z27_03960	COG3101	peptidyl-lysine hydroxylation
J8Z27_03985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J8Z27_03990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J8Z27_03995	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J8Z27_04005	COG0101	tRNA pseudouridine synthase activity
J8Z27_04010	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J8Z27_04015	COG0285	dihydrofolate synthase activity
J8Z27_04020	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
J8Z27_04025	COG1286	toxin biosynthetic process
J8Z27_04030	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J8Z27_04035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J8Z27_04040	COG1121	(ABC) transporter
J8Z27_04045	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
J8Z27_04050	COG4977	sequence-specific DNA binding
J8Z27_04055	COG1918	ferrous iron import across plasma membrane
J8Z27_04060	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J8Z27_04080	COG3102	Protein conserved in bacteria
J8Z27_04085	COG1025	Belongs to the peptidase M16 family
J8Z27_04090	COG2062	phosphohistidine phosphatase, SixA
J8Z27_04120	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
J8Z27_04125	COG2198	Histidine kinase
J8Z27_04125	COG0784	Response regulator, receiver
J8Z27_04125	COG0643	Histidine kinase
J8Z27_04130	COG2201	protein-glutamate methylesterase activity
J8Z27_04135	COG1192	Involved in chromosome partitioning
J8Z27_04145	COG0835	chemotaxis
J8Z27_04155	COG4133	protoheme IX ABC transporter activity
J8Z27_04160	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J8Z27_04165	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J8Z27_04170	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J8Z27_04180	COG1138	Cytochrome C-type biogenesis protein
J8Z27_04185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J8Z27_04200	COG2853	Lipoprotein
J8Z27_04205	COG2067	long-chain fatty acid transport protein
J8Z27_04210	COG2067	long-chain fatty acid transport protein
J8Z27_04225	COG0183	Belongs to the thiolase family
J8Z27_04235	COG0778	Nitroreductase
J8Z27_04240	COG0583	DNA-binding transcription factor activity
J8Z27_04245	COG0745	RESPONSE REGULATOR receiver
J8Z27_04250	COG2832	Protein of unknown function (DUF454)
J8Z27_04255	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J8Z27_04270	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J8Z27_04275	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J8Z27_04300	COG1653	transport
J8Z27_04305	COG1175	transmembrane transport
J8Z27_04315	COG3842	ATPase activity
J8Z27_04320	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J8Z27_04325	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J8Z27_04330	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J8Z27_04340	COG2204	response regulator
J8Z27_04360	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J8Z27_04365	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J8Z27_04370	COG0776	regulation of translation
J8Z27_04375	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J8Z27_04380	COG1555	photosystem II stabilization
J8Z27_04385	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J8Z27_04390	COG0539	negative regulation of cytoplasmic translation
J8Z27_04400	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
J8Z27_04405	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
J8Z27_04410	COG0284	orotidine-5'-phosphate decarboxylase activity
J8Z27_04440	COG4120	Belongs to the binding-protein-dependent transport system permease family
J8Z27_04450	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J8Z27_04465	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J8Z27_04470	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J8Z27_04475	COG0252	asparaginase activity
J8Z27_04480	COG0616	signal peptide processing
J8Z27_04485	COG1902	pentaerythritol trinitrate reductase activity
J8Z27_04485	COG0446	pyridine nucleotide-disulphide oxidoreductase
J8Z27_04490	COG0788	formyltetrahydrofolate deformylase activity
J8Z27_04500	COG1199	ATP-dependent helicase activity
J8Z27_04505	COG1214	PFAM Peptidase M22, glycoprotease
J8Z27_04520	COG0596	Alpha beta hydrolase
J8Z27_04525	COG0318	PFAM AMP-dependent synthetase and ligase
J8Z27_04530	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
J8Z27_04535	COG0659	secondary active sulfate transmembrane transporter activity
J8Z27_04540	COG1530	ribonuclease E activity
J8Z27_04545	COG0564	pseudouridine synthase activity
J8Z27_04555	COG1399	metal-binding, possibly nucleic acid-binding protein
J8Z27_04560	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J8Z27_04570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J8Z27_04595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J8Z27_04600	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J8Z27_04605	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J8Z27_04610	COG0470	DNA polymerase III
J8Z27_04615	COG0084	hydrolase, TatD family'
J8Z27_04620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J8Z27_04620	COG1263	PTS System
J8Z27_04635	COG0733	neurotransmitter:sodium symporter activity
J8Z27_04650	COG4667	esterase of the alpha-beta hydrolase superfamily
J8Z27_04655	COG0702	epimerase
J8Z27_04675	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J8Z27_04680	COG0840	transmembrane signaling receptor activity
J8Z27_04685	COG0632	four-way junction helicase activity
J8Z27_04690	COG2255	four-way junction helicase activity
J8Z27_04695	COG1271	oxidase subunit
J8Z27_04700	COG1294	oxidase, subunit
J8Z27_04705	COG4890	Cyd operon protein YbgT
J8Z27_04715	COG0824	Thioesterase
J8Z27_04720	COG0811	peptide transport
J8Z27_04735	COG0823	Involved in the tonB-independent uptake of proteins
J8Z27_04740	COG2885	chlorophyll binding
J8Z27_04745	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
J8Z27_04750	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J8Z27_04765	COG2205	protein histidine kinase activity
J8Z27_04765	COG0784	Response regulator, receiver
J8Z27_04780	COG1401	restriction endodeoxyribonuclease activity
J8Z27_04800	COG1902	pentaerythritol trinitrate reductase activity
J8Z27_04805	COG1881	PFAM PEBP family protein
J8Z27_04820	COG1940	carbohydrate kinase activity
J8Z27_04840	COG1960	acyl-CoA dehydrogenase activity
J8Z27_04845	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J8Z27_04855	COG0708	Exodeoxyribonuclease III
J8Z27_04860	COG0840	transmembrane signaling receptor activity
J8Z27_04865	COG2850	peptidyl-arginine hydroxylation
J8Z27_04880	COG0730	response to heat
J8Z27_04885	COG1199	ATP-dependent helicase activity
J8Z27_04900	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J8Z27_04910	COG0156	8-amino-7-oxononanoate synthase activity
J8Z27_04915	COG2226	methyltransferase
J8Z27_04915	COG1073	alpha beta
J8Z27_04920	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J8Z27_04930	COG0501	Belongs to the peptidase M48B family
J8Z27_04940	COG1028	Short-chain dehydrogenase reductase Sdr
J8Z27_04955	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J8Z27_04965	COG2268	Band 7 protein
J8Z27_04975	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J8Z27_04985	COG0482	sulfurtransferase activity
J8Z27_04995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J8Z27_05005	COG1757	Na H antiporter
J8Z27_05015	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J8Z27_05025	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J8Z27_05025	COG0131	Imidazoleglycerol-phosphate dehydratase
J8Z27_05030	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J8Z27_05035	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J8Z27_05045	COG0140	phosphoribosyl-ATP diphosphatase activity
J8Z27_05045	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J8Z27_05050	COG2202	Pas domain
J8Z27_05050	COG2200	EAL domain
J8Z27_05050	COG2199	diguanylate cyclase activity
J8Z27_05055	COG2205	protein histidine kinase activity
J8Z27_05055	COG0784	Response regulator, receiver
J8Z27_05075	COG1227	inorganic diphosphatase activity
J8Z27_05085	COG4172	Belongs to the ABC transporter superfamily
J8Z27_05095	COG4171	peptide transport system, permease
J8Z27_05110	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
J8Z27_05115	COG1842	Phage shock protein A
J8Z27_05145	COG2818	Glycosylase
J8Z27_05155	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J8Z27_05160	COG0626	cystathionine gamma-synthase activity
J8Z27_05170	COG0733	neurotransmitter:sodium symporter activity
J8Z27_05175	COG0564	pseudouridine synthase activity
J8Z27_05180	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J8Z27_05190	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J8Z27_05195	COG4136	ATPase activity
J8Z27_05200	COG4135	transport system, permease component
J8Z27_05205	COG4134	Bacterial extracellular solute-binding protein
J8Z27_05215	COG3313	Fe-S protein
J8Z27_05230	COG2350	Protein conserved in bacteria
J8Z27_05265	COG0776	regulation of translation
J8Z27_05275	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J8Z27_05285	COG0417	DNA replication proofreading
J8Z27_05300	COG2197	response regulator
J8Z27_05305	COG0322	excinuclease ABC activity
J8Z27_05335	COG1902	pentaerythritol trinitrate reductase activity
J8Z27_05345	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J8Z27_05355	COG1032	radical SAM domain protein
J8Z27_05380	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J8Z27_05390	COG1764	response to oxidative stress
J8Z27_05395	COG1846	Transcriptional regulator
J8Z27_05405	COG0583	DNA-binding transcription factor activity
J8Z27_05430	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J8Z27_05480	COG0443	Heat shock 70 kDa protein
J8Z27_05520	COG1643	Atp-dependent helicase
J8Z27_05535	COG0159	tryptophan synthase activity
J8Z27_05545	COG0134	indole-3-glycerol-phosphate synthase activity
J8Z27_05545	COG0135	phosphoribosylanthranilate isomerase activity
J8Z27_05550	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J8Z27_05555	COG0512	Glutamine amidotransferase of anthranilate synthase
J8Z27_05560	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J8Z27_05570	COG0613	PHP domain protein
J8Z27_05575	COG0009	L-threonylcarbamoyladenylate synthase
J8Z27_05590	COG1187	pseudouridine synthase activity
J8Z27_05595	COG0384	phenazine biosynthesis protein PhzF
J8Z27_05600	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J8Z27_05605	COG4988	ABC transporter
J8Z27_05610	COG0492	ferredoxin-NADP+ reductase activity
J8Z27_05625	COG0612	Peptidase, M16
J8Z27_05635	COG2949	membrane
J8Z27_05645	COG0281	malic enzyme
J8Z27_05650	COG1643	Atp-dependent helicase
J8Z27_05665	COG1448	Aminotransferase
J8Z27_05670	COG3437	response regulator, receiver
J8Z27_05670	COG2770	Histidine kinase
J8Z27_05680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J8Z27_05690	COG0017	Asparaginyl-tRNA synthetase
J8Z27_05695	COG0840	transmembrane signaling receptor activity
J8Z27_05700	COG0720	synthase
J8Z27_05705	COG0814	amino acid
J8Z27_05715	COG1760	l-serine dehydratase
J8Z27_05720	COG0814	amino acid
J8Z27_05725	COG0494	nUDIX hydrolase
J8Z27_05740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J8Z27_05755	COG3106	COG3106 Predicted ATPase
J8Z27_05770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Z27_05800	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J8Z27_05825	COG2989	Protein conserved in bacteria
J8Z27_05830	COG3108	Peptidase M15
J8Z27_05835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8Z27_05850	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J8Z27_05880	COG0783	Belongs to the Dps family
J8Z27_05890	COG0531	amino acid
J8Z27_05895	COG2962	Rard protein
J8Z27_05920	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J8Z27_05930	COG1942	4-Oxalocrotonate Tautomerase
J8Z27_06020	COG0346	lactoylglutathione lyase activity
J8Z27_06170	COG0251	oxidation-reduction process
J8Z27_06205	COG1028	Short-chain dehydrogenase reductase Sdr
J8Z27_06270	COG4628	conserved protein (DUF2132)
J8Z27_06480	COG3385	transposase activity
J8Z27_06615	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J8Z27_06660	COG3755	Protein conserved in bacteria
J8Z27_06690	COG0384	phenazine biosynthesis protein PhzF
J8Z27_06745	COG3385	transposase activity
J8Z27_06770	COG1280	lysine exporter protein (LysE YggA)
J8Z27_06775	COG2161	toxin-antitoxin pair type II binding
J8Z27_06780	COG4115	mRNA cleavage
J8Z27_06800	COG0384	phenazine biosynthesis protein PhzF
J8Z27_06880	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
J8Z27_06890	COG0625	glutathione transferase activity
J8Z27_06905	COG2885	chlorophyll binding
J8Z27_06920	COG0247	lactate metabolic process
J8Z27_06920	COG0277	FAD linked oxidase domain protein
J8Z27_06935	COG2986	histidine ammonia-lyase
J8Z27_06945	COG0010	Belongs to the arginase family
J8Z27_06950	COG1228	amidohydrolase
J8Z27_06955	COG2188	Transcriptional regulator
J8Z27_06960	COG4326	sporulation control protein
J8Z27_06980	COG0500	methyltransferase
J8Z27_06985	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J8Z27_06995	COG0295	cytidine deaminase activity
J8Z27_07000	COG1346	cytolysis
J8Z27_07005	COG1380	Effector of murein hydrolase LrgA
J8Z27_07010	COG2925	Exonuclease
J8Z27_07015	COG1823	symporter activity
J8Z27_07020	COG0702	epimerase
J8Z27_07025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J8Z27_07030	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J8Z27_07035	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J8Z27_07055	COG4139	cobalamin transport
J8Z27_07060	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
J8Z27_07085	COG0583	DNA-binding transcription factor activity
J8Z27_07090	COG1119	ATPase activity
J8Z27_07100	COG2205	protein histidine kinase activity
J8Z27_07100	COG0784	Response regulator, receiver
J8Z27_07110	COG1451	nucleotide metabolic process
J8Z27_07130	COG0508	dehydrogenase complex catalyzes the overall conversion of
J8Z27_07130	COG0596	Alpha beta hydrolase
J8Z27_07135	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
J8Z27_07150	COG2200	EAL domain
J8Z27_07165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J8Z27_07190	COG0515	serine threonine protein kinase
J8Z27_07305	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
J8Z27_07310	COG0372	Belongs to the citrate synthase family
J8Z27_07320	COG2828	Protein conserved in bacteria
J8Z27_07340	COG0561	phosphatase activity
J8Z27_07345	COG0602	queuosine metabolic process
J8Z27_07380	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J8Z27_07385	COG0840	transmembrane signaling receptor activity
J8Z27_07390	COG1254	Belongs to the acylphosphatase family
J8Z27_07395	COG2920	part of a sulfur-relay system
J8Z27_07400	COG0670	Belongs to the BI1 family
J8Z27_07405	COG1126	abc transporter atp-binding protein
J8Z27_07410	COG0765	amino acid transport
J8Z27_07415	COG4597	amino acid ABC transporter
J8Z27_07420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J8Z27_07425	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J8Z27_07425	COG1648	precorrin-2 dehydrogenase activity
J8Z27_07435	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J8Z27_07440	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J8Z27_07460	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J8Z27_07460	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
J8Z27_07465	COG3008	intermembrane lipid transfer
J8Z27_07470	COG2995	paraquat-inducible protein a
J8Z27_07475	COG1132	(ABC) transporter
J8Z27_07480	COG1956	GAF domain-containing protein
J8Z27_07485	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
J8Z27_07500	COG0308	aminopeptidase N
J8Z27_07515	COG0167	dihydroorotate dehydrogenase activity
J8Z27_07525	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J8Z27_07525	COG0116	Belongs to the methyltransferase superfamily
J8Z27_07535	COG0488	(ABC) transporter
J8Z27_07550	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J8Z27_07555	COG1067	ATP-dependent peptidase activity
J8Z27_07560	COG3120	sequence-specific DNA binding
J8Z27_07605	COG0840	transmembrane signaling receptor activity
J8Z27_07610	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J8Z27_07750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8Z27_07765	COG3278	Belongs to the heme-copper respiratory oxidase family
J8Z27_07780	COG2010	Cytochrome c
J8Z27_07790	COG2217	Heavy metal translocating P-type atpase
J8Z27_07805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J8Z27_07810	COG0589	response to stress
J8Z27_07835	COG3842	ATPase activity
J8Z27_07845	COG1177	transmembrane transport
J8Z27_07850	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J8Z27_07860	COG2199	diguanylate cyclase activity
J8Z27_07865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J8Z27_07880	COG0583	DNA-binding transcription factor activity
J8Z27_07895	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
J8Z27_07925	COG0488	(ABC) transporter
J8Z27_07935	COG1595	DNA-templated transcription, initiation
J8Z27_07945	COG1910	domain protein
J8Z27_07950	COG0746	molybdenum cofactor guanylyltransferase activity
J8Z27_07955	COG1763	Mo-molybdopterin cofactor biosynthetic process
J8Z27_07985	COG1940	carbohydrate kinase activity
J8Z27_07990	COG3148	PFAM DTW domain containing protein
J8Z27_08000	COG3290	protein histidine kinase activity
J8Z27_08000	COG0840	transmembrane signaling receptor activity
J8Z27_08005	COG0791	NLP P60 protein
J8Z27_08015	COG3001	Fructosamine kinase
J8Z27_08025	COG0307	riboflavin synthase, alpha
J8Z27_08030	COG0534	Mate efflux family protein
J8Z27_08075	COG2204	response regulator
J8Z27_08085	COG0438	transferase activity, transferring glycosyl groups
J8Z27_08120	COG0297	glycogen (starch) synthase activity
J8Z27_08130	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J8Z27_08150	COG1196	nuclear chromosome segregation
J8Z27_08165	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
J8Z27_08210	COG3293	Transposase
J8Z27_08240	COG4774	siderophore transport
J8Z27_08260	COG4615	Cyclic peptide transporter
J8Z27_08270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J8Z27_08275	COG1120	ATPase activity
J8Z27_08280	COG2977	Belongs to the P-Pant transferase superfamily
J8Z27_08285	COG1929	Belongs to the glycerate kinase type-1 family
J8Z27_08290	COG3835	regulator
J8Z27_08295	COG0583	DNA-binding transcription factor activity
J8Z27_08305	COG3385	transposase activity
J8Z27_08310	COG3713	MltA-interacting MipA family protein
J8Z27_08315	COG2205	protein histidine kinase activity
J8Z27_08320	COG0745	RESPONSE REGULATOR receiver
J8Z27_08340	COG2116	formate transmembrane transporter activity
J8Z27_08350	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J8Z27_08355	COG2199	diguanylate cyclase activity
J8Z27_08360	COG2195	Cleaves the N-terminal amino acid of tripeptides
J8Z27_08385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Z27_08390	COG0454	-acetyltransferase
J8Z27_08435	COG3122	Protein conserved in bacteria
J8Z27_08455	COG4565	transcriptional regulatory protein
J8Z27_08460	COG3290	protein histidine kinase activity
J8Z27_08480	COG0848	biopolymer transport protein
J8Z27_08485	COG0811	peptide transport
J8Z27_08490	COG0811	peptide transport
J8Z27_08525	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J8Z27_08530	COG1328	CTP reductase activity
J8Z27_08535	COG0840	transmembrane signaling receptor activity
J8Z27_08545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J8Z27_08550	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J8Z27_08555	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J8Z27_08560	COG0633	Ferredoxin
J8Z27_08585	COG0019	diaminopimelate decarboxylase activity
J8Z27_08610	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J8Z27_08620	COG0577	efflux transmembrane transporter activity
J8Z27_08625	COG1136	(ABC) transporter
J8Z27_08630	COG0534	Mate efflux family protein
J8Z27_08635	COG0702	epimerase
J8Z27_08645	COG2814	Major facilitator Superfamily
J8Z27_08655	COG1061	Type III restriction enzyme res subunit
J8Z27_08695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J8Z27_08700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J8Z27_08715	COG0463	Glycosyl transferase, family 2
J8Z27_08765	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J8Z27_08815	COG0242	peptide deformylase activity
J8Z27_08820	COG0519	Catalyzes the synthesis of GMP from XMP
J8Z27_08830	COG4580	involved in the transport of maltose and maltodextrins
J8Z27_08835	COG3040	lipid binding
J8Z27_08845	COG2824	Alkylphosphonate utilization operon protein PhnA
J8Z27_08900	COG1115	amino acid carrier protein
J8Z27_08905	COG1280	lysine exporter protein (LysE YggA)
J8Z27_08910	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
J8Z27_08915	COG0352	thiamine-phosphate diphosphorylase activity
J8Z27_08930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J8Z27_08940	COG1012	belongs to the aldehyde dehydrogenase family
J8Z27_08950	COG0583	DNA-binding transcription factor activity
J8Z27_08970	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J8Z27_08980	COG1609	Transcriptional regulator
J8Z27_08985	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J8Z27_08995	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J8Z27_08995	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J8Z27_09010	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J8Z27_09015	COG1609	Transcriptional regulator
J8Z27_09030	COG1278	Cold shock
J8Z27_09055	COG1538	Outer membrane efflux protein
J8Z27_09060	COG1858	cytochrome C peroxidase
J8Z27_09065	COG0784	Response regulator, receiver
J8Z27_09065	COG2205	protein histidine kinase activity
J8Z27_09080	COG0277	FAD linked oxidase domain protein
J8Z27_09085	COG0583	DNA-binding transcription factor activity
J8Z27_09105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J8Z27_09145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J8Z27_09145	COG0072	phenylalanine-tRNA ligase activity
J8Z27_09175	COG2133	pyrroloquinoline quinone binding
J8Z27_09185	COG4191	Histidine kinase
J8Z27_09200	COG3070	regulator of competence-specific genes
J8Z27_09210	COG2431	L-lysine efflux transmembrane transporter activity
J8Z27_09220	COG0076	glutamate decarboxylase activity
J8Z27_09225	COG1737	Transcriptional regulator
J8Z27_09230	COG1454	alcohol dehydrogenase
J8Z27_09230	COG1012	belongs to the aldehyde dehydrogenase family
J8Z27_09235	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J8Z27_09270	COG1882	Formate acetyltransferase
J8Z27_09285	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J8Z27_09295	COG3013	Belongs to the UPF0304 family
J8Z27_09300	COG2766	serine protein kinase
J8Z27_09305	COG2718	Belongs to the UPF0229 family
J8Z27_09310	COG2719	SpoVR family
J8Z27_09315	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J8Z27_09320	COG2835	tetraacyldisaccharide 4'-kinase activity
J8Z27_09330	COG1132	(ABC) transporter
J8Z27_09335	COG0658	competence protein
J8Z27_09335	COG2333	competence protein COMEC
J8Z27_09345	COG4591	ABC-type transport system involved in lipoprotein release permease component
J8Z27_09350	COG1136	(ABC) transporter
J8Z27_09355	COG4591	ABC-type transport system involved in lipoprotein release permease component
J8Z27_09365	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J8Z27_09380	COG1252	NADH dehydrogenase
J8Z27_09385	COG3150	esterase
J8Z27_09410	COG0537	adenosine 5'-monophosphoramidase activity
J8Z27_09425	COG2186	Transcriptional regulator
J8Z27_09430	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J8Z27_09440	COG1674	ftsk spoiiie
J8Z27_09450	COG0686	Belongs to the AlaDH PNT family
J8Z27_09455	COG3092	negative regulation of chromosome organization
J8Z27_09460	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J8Z27_09465	COG0857	belongs to the CobB CobQ family
J8Z27_09465	COG0280	phosphate acetyltransferase
J8Z27_09470	COG0435	Glutathione S-transferase
J8Z27_09480	COG0444	Belongs to the ABC transporter superfamily
J8Z27_09485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J8Z27_09490	COG0601	transmembrane transport
J8Z27_09505	COG2067	long-chain fatty acid transport protein
J8Z27_09515	COG0840	transmembrane signaling receptor activity
J8Z27_09525	COG1404	Belongs to the peptidase S8 family
J8Z27_09530	COG0840	transmembrane signaling receptor activity
J8Z27_09555	COG0577	efflux transmembrane transporter activity
J8Z27_09555	COG1136	(ABC) transporter
J8Z27_09565	COG0577	efflux transmembrane transporter activity
J8Z27_09575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J8Z27_09590	COG1770	oligopeptidase
J8Z27_09680	COG3706	GGDEF domain
J8Z27_09695	COG3126	Type III secretion system lipoprotein chaperone (YscW)
J8Z27_09700	COG1946	Acyl-CoA thioesterase
J8Z27_09705	COG1522	sequence-specific DNA binding
J8Z27_09730	COG0477	Major facilitator Superfamily
J8Z27_09735	COG2855	membrane
J8Z27_09765	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
J8Z27_09770	COG1169	isochorismate synthase
J8Z27_09775	COG0436	Aminotransferase
J8Z27_09780	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
J8Z27_09785	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J8Z27_09790	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J8Z27_09805	COG0513	Belongs to the DEAD box helicase family
J8Z27_09815	COG0616	signal peptide processing
J8Z27_09820	COG1028	Short-chain dehydrogenase reductase Sdr
J8Z27_09825	COG0469	pyruvate kinase activity
J8Z27_09830	COG1940	carbohydrate kinase activity
J8Z27_09835	COG0784	Response regulator, receiver
J8Z27_09835	COG0835	chemotaxis
J8Z27_09850	COG0243	molybdopterin cofactor binding
J8Z27_09855	COG3005	denitrification pathway
J8Z27_09860	COG4459	periplasmic nitrate reductase
J8Z27_09865	COG0390	transport system, permease component
J8Z27_09875	COG2116	formate transmembrane transporter activity
J8Z27_09900	COG0542	response to heat
J8Z27_09910	COG1278	Cold shock
J8Z27_09920	COG1187	pseudouridine synthase activity
J8Z27_09930	COG1801	Protein of unknown function DUF72
J8Z27_09940	COG0500	methyltransferase
J8Z27_09945	COG4067	protein conserved in archaea
J8Z27_09945	COG0189	ligase activity
J8Z27_09960	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J8Z27_09965	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
J8Z27_09975	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J8Z27_09980	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J8Z27_09985	COG0745	RESPONSE REGULATOR receiver
J8Z27_10000	COG3070	regulator of competence-specific genes
J8Z27_10005	COG3385	transposase activity
J8Z27_10025	COG0297	glycogen (starch) synthase activity
J8Z27_10030	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J8Z27_10035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J8Z27_10055	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J8Z27_10060	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
J8Z27_10065	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J8Z27_10070	COG1435	thymidine kinase activity
J8Z27_10075	COG0215	cysteine-tRNA ligase activity
J8Z27_10080	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J8Z27_10085	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J8Z27_10090	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J8Z27_10095	COG3012	SEC-C Motif Domain Protein
J8Z27_10100	COG3139	Protein of unknown function (DUF1315)
J8Z27_10110	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J8Z27_10125	COG2226	methyltransferase
J8Z27_10140	COG1785	Belongs to the alkaline phosphatase family
J8Z27_10145	COG2771	luxR family
J8Z27_10155	COG2814	Major facilitator Superfamily
J8Z27_10160	COG1028	Short-chain dehydrogenase reductase Sdr
J8Z27_10185	COG2951	lytic endotransglycosylase activity
J8Z27_10190	COG3100	YcgL domain-containing protein
J8Z27_10195	COG0850	regulation of cytokinetic process
J8Z27_10200	COG2894	cell division
J8Z27_10205	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
J8Z27_10210	COG1454	alcohol dehydrogenase
J8Z27_10210	COG1012	belongs to the aldehyde dehydrogenase family
J8Z27_10215	COG2095	MarC family integral membrane protein
J8Z27_10220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J8Z27_10225	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J8Z27_10230	COG1757	Na H antiporter
J8Z27_10235	COG2188	Transcriptional regulator
J8Z27_10240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J8Z27_10240	COG1263	PTS System
J8Z27_10245	COG1621	beta-fructofuranosidase activity
J8Z27_10255	COG3081	Nucleoid-associated protein
J8Z27_10260	COG3082	Protein of unknown function (DUF1414)
J8Z27_10265	COG3083	sulfuric ester hydrolase activity
J8Z27_10290	COG0123	including yeast histone deacetylase and acetoin utilization protein
J8Z27_10300	COG1881	PFAM PEBP family protein
J8Z27_10310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J8Z27_10315	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J8Z27_10335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J8Z27_10340	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
J8Z27_10380	COG0383	alpha-mannosidase activity
J8Z27_10400	COG1940	carbohydrate kinase activity
J8Z27_10405	COG2982	Protein involved in outer membrane biogenesis
J8Z27_10410	COG0572	uridine kinase
J8Z27_10415	COG0489	protein tyrosine kinase activity
J8Z27_10420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J8Z27_10420	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J8Z27_10450	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J8Z27_10450	COG0517	IMP dehydrogenase activity
J8Z27_10450	COG0617	tRNA 3'-terminal CCA addition
J8Z27_10460	COG3706	GGDEF domain
J8Z27_10465	COG0314	molybdopterin synthase activity
J8Z27_10470	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J8Z27_10475	COG0315	cyclic pyranopterin monophosphate synthase activity
J8Z27_10480	COG0521	Mo-molybdopterin cofactor biosynthetic process
J8Z27_10485	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J8Z27_10490	COG0391	Required for morphogenesis under gluconeogenic growth conditions
J8Z27_10495	COG2198	Histidine kinase
J8Z27_10505	COG0556	nucleotide-excision repair
J8Z27_10530	COG0739	heme binding
J8Z27_10595	COG1987	bacterial-type flagellum assembly
J8Z27_10620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J8Z27_10625	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J8Z27_10630	COG1516	flagellar protein fliS
J8Z27_10645	COG1580	Controls the rotational direction of flagella during chemotaxis
J8Z27_10650	COG1191	sigma factor activity
J8Z27_10655	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J8Z27_10660	COG1360	Flagellar Motor Protein
J8Z27_10690	COG1706	bacterial-type flagellum-dependent cell motility
J8Z27_10695	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J8Z27_10700	COG4786	Flagellar basal body rod
J8Z27_10705	COG4787	bacterial-type flagellum-dependent cell motility
J8Z27_10710	COG1749	Flagellar hook protein flgE
J8Z27_10715	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
J8Z27_10720	COG1558	bacterial-type flagellum-dependent cell motility
J8Z27_10725	COG1815	bacterial-type flagellum-dependent cell motility
J8Z27_10745	COG0741	lytic transglycosylase activity
J8Z27_10745	COG1388	LysM domain
J8Z27_10750	COG4657	Part of a membrane complex involved in electron transport
J8Z27_10760	COG4656	Part of a membrane complex involved in electron transport
J8Z27_10765	COG4658	electron transport chain
J8Z27_10770	COG4659	FMN binding
J8Z27_10775	COG4660	Part of a membrane complex involved in electron transport
J8Z27_10780	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J8Z27_10785	COG0346	lactoylglutathione lyase activity
J8Z27_10805	COG2056	Na+-H+ antiporter family
J8Z27_10810	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
J8Z27_10820	COG2716	regulation of RNA biosynthetic process
J8Z27_10825	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J8Z27_10845	COG4783	chaperone-mediated protein folding
J8Z27_10850	COG1393	Belongs to the ArsC family
J8Z27_10870	COG2233	PERMEase
J8Z27_10875	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J8Z27_10885	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J8Z27_10890	COG2912	Transglutaminase-like superfamily
J8Z27_10900	COG2890	protein-(glutamine-N5) methyltransferase activity
J8Z27_10905	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J8Z27_10920	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J8Z27_10925	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J8Z27_11050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J8Z27_11060	COG3951	Flagellar rod assembly protein muramidase FlgJ
J8Z27_11060	COG1705	Flagellar rod assembly protein muramidase FlgJ
J8Z27_11065	COG1706	bacterial-type flagellum-dependent cell motility
J8Z27_11070	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J8Z27_11080	COG4787	bacterial-type flagellum-dependent cell motility
J8Z27_11100	COG1815	bacterial-type flagellum-dependent cell motility
J8Z27_11105	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J8Z27_11110	COG0835	chemotaxis
J8Z27_11110	COG0784	Response regulator, receiver
J8Z27_11120	COG2747	anti-sigma28 factor FlgM
J8Z27_11150	COG0500	methyltransferase
J8Z27_11175	COG2608	mercury ion transmembrane transporter activity
J8Z27_11175	COG2217	Heavy metal translocating P-type atpase
J8Z27_11185	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
J8Z27_11200	COG0583	DNA-binding transcription factor activity
J8Z27_11205	COG0301	tRNA thio-modification
J8Z27_11205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J8Z27_11215	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J8Z27_11220	COG1722	exodeoxyribonuclease VII activity
J8Z27_11225	COG0142	geranyltranstransferase activity
J8Z27_11235	COG0564	pseudouridine synthase activity
J8Z27_11240	COG3098	single-species biofilm formation
J8Z27_11255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Z27_11275	COG0508	dehydrogenase complex catalyzes the overall conversion of
J8Z27_11280	COG0567	Dehydrogenase, E1 component
J8Z27_11290	COG1053	succinate dehydrogenase
J8Z27_11295	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
J8Z27_11310	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J8Z27_11320	COG0033	Phosphoglucomutase
J8Z27_11325	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
J8Z27_11330	COG0596	Alpha beta hydrolase
J8Z27_11340	COG0716	FMN binding
J8Z27_11345	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J8Z27_11350	COG3115	cell septum assembly
J8Z27_11355	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
J8Z27_11360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J8Z27_11365	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J8Z27_11370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J8Z27_11375	COG2190	(PTS) system
J8Z27_11380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J8Z27_11385	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J8Z27_11390	COG1702	phosphate starvation-inducible protein PhoH
J8Z27_11395	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J8Z27_11400	COG4535	Mg2 and Co2 transporter CorC
J8Z27_11405	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J8Z27_11410	COG2888	peptidyl-tyrosine sulfation
J8Z27_11415	COG0495	leucyl-tRNA aminoacylation
J8Z27_11420	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
J8Z27_11425	COG1466	dna polymerase III delta subunit
J8Z27_11430	COG0799	negative regulation of ribosome biogenesis
J8Z27_11435	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J8Z27_11440	COG0768	penicillin binding
J8Z27_11445	COG0772	Belongs to the SEDS family
J8Z27_11450	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J8Z27_11455	COG1686	Belongs to the peptidase S11 family
J8Z27_11460	COG2921	Belongs to the UPF0250 family
J8Z27_11470	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J8Z27_11485	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J8Z27_11495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J8Z27_11500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J8Z27_11525	COG0366	Alpha amylase catalytic
J8Z27_11530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J8Z27_11530	COG1263	PTS System
J8Z27_11535	COG1609	Transcriptional regulator
J8Z27_11545	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J8Z27_11550	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J8Z27_11555	COG2011	ABC-type metal ion transport system permease component
J8Z27_11560	COG1464	Belongs to the NlpA lipoprotein family
J8Z27_11565	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J8Z27_11575	COG0254	rRNA binding
J8Z27_11580	COG1720	tRNA m6t6A37 methyltransferase activity
J8Z27_11590	COG0121	glutamine amidotransferase
J8Z27_11595	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J8Z27_11600	COG1960	acyl-CoA dehydrogenase activity
J8Z27_11615	COG0328	RNA-DNA hybrid ribonuclease activity
J8Z27_11620	COG2226	methyltransferase
J8Z27_11625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8Z27_11630	COG1388	LysM domain
J8Z27_11630	COG0741	lytic transglycosylase activity
J8Z27_11640	COG3021	interspecies interaction between organisms
J8Z27_11645	COG0347	Belongs to the P(II) protein family
J8Z27_11660	COG0825	malonyl-CoA metabolic process
J8Z27_11665	COG0587	DNA-directed DNA polymerase activity
J8Z27_11670	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J8Z27_11675	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J8Z27_11685	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J8Z27_11690	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J8Z27_11695	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
J8Z27_11700	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J8Z27_11705	COG0750	zinc metalloprotease
J8Z27_11715	COG0575	Belongs to the CDS family
J8Z27_11720	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J8Z27_11725	COG0233	cytoplasmic translational termination
J8Z27_11730	COG0528	UMP kinase activity
J8Z27_11740	COG0052	Belongs to the universal ribosomal protein uS2 family
J8Z27_11745	COG0024	Methionine aminopeptidase
J8Z27_11750	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
J8Z27_11760	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J8Z27_11765	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J8Z27_11770	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J8Z27_11790	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J8Z27_11790	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J8Z27_11795	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J8Z27_11800	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J8Z27_11805	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J8Z27_11815	COG1073	alpha beta
J8Z27_11820	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
J8Z27_11825	COG2252	PERMEase
J8Z27_11830	COG2195	Cleaves the N-terminal amino acid of tripeptides
J8Z27_11835	COG4067	protein conserved in archaea
J8Z27_11835	COG0189	ligase activity
J8Z27_11840	COG0189	ligase activity
J8Z27_11850	COG0733	neurotransmitter:sodium symporter activity
J8Z27_11865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J8Z27_11870	COG0514	ATP-dependent DNA helicase (RecQ)
J8Z27_11875	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J8Z27_11890	COG1477	protein flavinylation
J8Z27_11895	COG2871	sodium ion transport
J8Z27_11900	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J8Z27_11905	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J8Z27_11915	COG1805	sodium ion transport
J8Z27_11920	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J8Z27_11925	COG0271	Belongs to the BolA IbaG family
J8Z27_11930	COG2813	Specifically methylates the guanine in position
J8Z27_11960	COG1595	DNA-templated transcription, initiation
J8Z27_11975	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J8Z27_11980	COG0693	protein deglycase activity
J8Z27_11985	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J8Z27_11990	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J8Z27_12000	COG0560	Phosphoserine phosphatase
J8Z27_12010	COG0813	purine-nucleoside phosphorylase activity
J8Z27_12015	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
J8Z27_12020	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
J8Z27_12035	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J8Z27_12040	COG0084	hydrolase, TatD family'
J8Z27_12050	COG3022	response to hydroperoxide
J8Z27_12055	COG1115	amino acid carrier protein
J8Z27_12070	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J8Z27_12080	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
J8Z27_12085	COG0583	DNA-binding transcription factor activity
J8Z27_12090	COG0730	response to heat
J8Z27_12095	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J8Z27_12100	COG0505	Belongs to the CarA family
J8Z27_12110	COG0494	nUDIX hydrolase
J8Z27_12115	COG0653	protein targeting
J8Z27_12120	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J8Z27_12125	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J8Z27_12130	COG0849	cell division
J8Z27_12135	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J8Z27_12150	COG0772	Belongs to the SEDS family
J8Z27_12155	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J8Z27_12165	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J8Z27_12170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J8Z27_12175	COG0768	penicillin binding
J8Z27_12180	COG3116	cell division
J8Z27_12195	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J8Z27_12200	COG3107	peptidoglycan biosynthetic process
J8Z27_12205	COG0792	nuclease activity
J8Z27_12210	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J8Z27_12220	COG2969	positive regulation of protein catabolic process
J8Z27_12225	COG0625	glutathione transferase activity
J8Z27_12230	COG2857	Cytochrome c1
J8Z27_12235	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J8Z27_12240	COG0723	plastoquinol--plastocyanin reductase activity
J8Z27_12255	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J8Z27_12260	COG3105	Protein conserved in bacteria
J8Z27_12265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J8Z27_12270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J8Z27_12285	COG3150	esterase
J8Z27_12295	COG3151	Protein conserved in bacteria
J8Z27_12300	COG0494	nUDIX hydrolase
J8Z27_12305	COG1538	Outer membrane efflux protein
J8Z27_12315	COG0784	Response regulator, receiver
J8Z27_12315	COG5002	protein histidine kinase activity
J8Z27_12315	COG2198	Histidine kinase
J8Z27_12320	COG5001	Diguanylate cyclase
J8Z27_12320	COG4251	negative regulation of phosphorylation
J8Z27_12320	COG3706	GGDEF domain
J8Z27_12320	COG2203	Gaf domain
J8Z27_12325	COG1242	4 iron, 4 sulfur cluster binding
J8Z27_12330	COG0070	glutamate synthase
J8Z27_12330	COG0069	glutamate synthase activity
J8Z27_12330	COG0067	glutamate synthase
J8Z27_12340	COG0069	glutamate synthase activity
J8Z27_12340	COG0070	glutamate synthase
J8Z27_12340	COG0067	glutamate synthase
J8Z27_12345	COG0493	'glutamate synthase
J8Z27_12370	COG0195	Participates in both transcription termination and antitermination
J8Z27_12375	COG0779	Required for maturation of 30S ribosomal subunits
J8Z27_12450	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J8Z27_12455	COG3153	acetyltransferase
J8Z27_12460	COG3154	lipid carrier protein
J8Z27_12470	COG0826	peptidase U32
J8Z27_12475	COG0826	peptidase U32
J8Z27_12480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J8Z27_12500	COG0513	Belongs to the DEAD box helicase family
J8Z27_12515	COG0456	acetyltransferase
J8Z27_12525	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J8Z27_12530	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J8Z27_12535	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J8Z27_12540	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
J8Z27_12545	COG1534	Rna-binding protein
J8Z27_12550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J8Z27_12555	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J8Z27_12570	COG0316	Belongs to the HesB IscA family
J8Z27_12580	COG0628	permease
J8Z27_12585	COG2813	Specifically methylates the guanine in position
J8Z27_12590	COG0784	Response regulator, receiver
J8Z27_12590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J8Z27_12590	COG2198	Histidine kinase
J8Z27_12590	COG2205	protein histidine kinase activity
J8Z27_12595	COG0747	negative chemotaxis
J8Z27_12610	COG0444	Belongs to the ABC transporter superfamily
J8Z27_12615	COG4608	Belongs to the ABC transporter superfamily
J8Z27_12625	COG2971	BadF BadG BcrA BcrD
J8Z27_12640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J8Z27_12645	COG3842	ATPase activity
J8Z27_12655	COG1840	ABC-type Fe3 transport system, periplasmic component
J8Z27_12660	COG0004	ammonium transporteR
J8Z27_12670	COG3112	Uncharacterised protein family (UPF0231)
J8Z27_12675	COG1049	propionate catabolic process, 2-methylcitrate cycle
J8Z27_12680	COG1752	Esterase of the alpha-beta hydrolase superfamily
J8Z27_12685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J8Z27_12760	COG3119	arylsulfatase activity
J8Z27_12765	COG1309	transcriptional regulator
J8Z27_12795	COG1643	Atp-dependent helicase
J8Z27_12805	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J8Z27_12820	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J8Z27_12825	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J8Z27_12835	COG0842	Transport permease protein
J8Z27_12840	COG1131	(ABC) transporter
J8Z27_12845	COG0659	secondary active sulfate transmembrane transporter activity
J8Z27_12850	COG0288	reversible hydration of carbon dioxide
J8Z27_12865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J8Z27_12870	COG0508	dehydrogenase complex catalyzes the overall conversion of
J8Z27_12875	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
J8Z27_12880	COG2186	Transcriptional regulator
J8Z27_12885	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J8Z27_12890	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J8Z27_12895	COG4974	Belongs to the 'phage' integrase family
J8Z27_12900	COG0716	FMN binding
J8Z27_12910	COG0157	Belongs to the NadC ModD family
J8Z27_12915	COG4969	Belongs to the N-Me-Phe pilin family
J8Z27_12920	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J8Z27_12925	COG1459	type II secretion system
J8Z27_12935	COG0237	dephospho-CoA kinase activity
J8Z27_12940	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
J8Z27_12945	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
J8Z27_12955	COG0336	Belongs to the RNA methyltransferase TrmD family
J8Z27_12965	COG0228	four-way junction DNA binding
J8Z27_12970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J8Z27_12975	COG4137	Cytochrome C assembly protein
J8Z27_12980	COG4536	flavin adenine dinucleotide binding
J8Z27_12985	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J8Z27_12990	COG1388	LysM domain
J8Z27_12990	COG4942	peptidase
J8Z27_13000	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J8Z27_13005	COG0585	pseudouridine synthase activity
J8Z27_13010	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J8Z27_13015	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J8Z27_13020	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J8Z27_13025	COG1968	undecaprenyl-diphosphatase activity
J8Z27_13030	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J8Z27_13035	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J8Z27_13040	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J8Z27_13045	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J8Z27_13050	COG3385	transposase activity
J8Z27_13055	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J8Z27_13060	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J8Z27_13065	COG1610	YqeY-like protein
J8Z27_13070	COG0358	DNA primase activity
J8Z27_13085	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
J8Z27_13090	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
J8Z27_13095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J8Z27_13100	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J8Z27_13105	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J8Z27_13115	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J8Z27_13120	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J8Z27_13125	COG3610	response to peptide
J8Z27_13130	COG2966	Psort location CytoplasmicMembrane, score
J8Z27_13135	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J8Z27_13145	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J8Z27_13150	COG0142	geranyltranstransferase activity
J8Z27_13200	COG3437	response regulator, receiver
J8Z27_13215	COG0270	DNA (cytosine-5-)-methyltransferase activity
J8Z27_13250	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J8Z27_13315	COG1854	S-ribosylhomocysteine lyase activity
J8Z27_13330	COG0612	Peptidase, M16
J8Z27_13335	COG1238	metal cluster binding
J8Z27_13345	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
J8Z27_13350	COG0511	ligase activity, forming carbon-carbon bonds
J8Z27_13350	COG5016	pyruvate
J8Z27_13355	COG3630	sodium ion export across plasma membrane
J8Z27_13420	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J8Z27_13425	COG1546	Belongs to the CinA family
J8Z27_13430	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J8Z27_13435	COG0795	lipopolysaccharide-transporting ATPase activity
J8Z27_13440	COG0795	lipopolysaccharide-transporting ATPase activity
J8Z27_13450	COG2927	DNA polymerase III (CHI subunit)
J8Z27_13455	COG0525	valine-tRNA ligase activity
J8Z27_13465	COG4269	membrane
J8Z27_13475	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J8Z27_13480	COG0564	pseudouridine synthase activity
J8Z27_13495	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J8Z27_13510	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
J8Z27_13515	COG0251	oxidation-reduction process
J8Z27_13525	COG0039	L-malate dehydrogenase activity
J8Z27_13530	COG1438	arginine binding
J8Z27_13535	COG2358	TRAP transporter, solute receptor (TAXI family
J8Z27_13545	COG0589	response to stress
J8Z27_13570	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J8Z27_13575	COG0527	aspartate kinase activity
J8Z27_13580	COG0312	modulator of DNA gyrase
J8Z27_13585	COG3028	Belongs to the UPF0307 family
J8Z27_13590	COG0204	Acyl-transferase
J8Z27_13595	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J8Z27_13600	COG5007	Belongs to the BolA IbaG family
J8Z27_13610	COG2854	intermembrane phospholipid transfer
J8Z27_13615	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J8Z27_13620	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J8Z27_13625	COG1127	ABC transporter
J8Z27_13635	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J8Z27_13635	COG0517	IMP dehydrogenase activity
J8Z27_13640	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
J8Z27_13650	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J8Z27_13655	COG1137	ATPase activity
J8Z27_13665	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J8Z27_13670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J8Z27_13675	COG1660	Displays ATPase and GTPase activities
J8Z27_13680	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J8Z27_13685	COG2239	Acts as a magnesium transporter
J8Z27_13690	COG0646	methionine synthase
J8Z27_13690	COG1410	methionine synthase
J8Z27_13760	COG0175	sulfate reduction
J8Z27_13765	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J8Z27_13770	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J8Z27_13795	COG3437	response regulator, receiver
J8Z27_13800	COG5002	protein histidine kinase activity
J8Z27_13800	COG0784	Response regulator, receiver
J8Z27_13800	COG2205	protein histidine kinase activity
J8Z27_13805	COG0735	belongs to the Fur family
J8Z27_13815	COG0529	Catalyzes the synthesis of activated sulfate
J8Z27_13820	COG3273	potassium ion transport
J8Z27_13820	COG0471	metal ion transport
J8Z27_13835	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J8Z27_13835	COG1648	precorrin-2 dehydrogenase activity
J8Z27_13840	COG0737	Belongs to the 5'-nucleotidase family
J8Z27_13850	COG2153	protein acetylation
J8Z27_13865	COG0545	Peptidyl-prolyl cis-trans isomerase
J8Z27_13875	COG0203	ribosomal protein L17
J8Z27_13880	COG0202	RNA polymerase activity
J8Z27_13890	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J8Z27_13895	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J8Z27_13900	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J8Z27_13905	COG0201	protein transport
J8Z27_13910	COG0200	Binds to the 23S rRNA
J8Z27_13915	COG1841	ribosomal large subunit assembly
J8Z27_13930	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J8Z27_13935	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J8Z27_13945	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J8Z27_13960	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J8Z27_13975	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J8Z27_13980	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J8Z27_13985	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J8Z27_14000	COG0088	Forms part of the polypeptide exit tunnel
J8Z27_14005	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J8Z27_14010	COG0051	transcription antitermination factor activity, RNA binding
J8Z27_14015	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J8Z27_14020	COG0557	exoribonuclease II activity
J8Z27_14025	COG0402	S-adenosylhomocysteine deaminase activity
J8Z27_14030	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
J8Z27_14035	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J8Z27_14045	COG1047	Peptidyl-prolyl cis-trans
J8Z27_14060	COG2249	NAD(P)H dehydrogenase (quinone) activity
J8Z27_14065	COG0488	(ABC) transporter
J8Z27_14075	COG0429	hydrolase of the alpha beta-hydrolase fold
J8Z27_14080	COG3089	Belongs to the UPF0270 family
J8Z27_14085	COG3954	Phosphoribulokinase
J8Z27_14090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J8Z27_14095	COG0471	metal ion transport
J8Z27_14095	COG0490	domain, Protein
J8Z27_14110	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J8Z27_14115	COG4942	peptidase
J8Z27_14135	COG2816	NAD+ diphosphatase activity
J8Z27_14140	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
J8Z27_14145	COG1288	antiporter activity
J8Z27_14160	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J8Z27_14165	COG0540	Belongs to the ATCase OTCase family
J8Z27_14170	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
J8Z27_14175	COG1438	arginine binding
J8Z27_14180	COG4232	protein-disulfide reductase activity
J8Z27_14190	COG2095	MarC family integral membrane protein
J8Z27_14200	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J8Z27_14220	COG0149	triose-phosphate isomerase activity
J8Z27_14225	COG0534	Mate efflux family protein
J8Z27_14230	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J8Z27_14235	COG1575	Belongs to the MenA family. Type 1 subfamily
J8Z27_14240	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J8Z27_14245	COG1509	lysine 2,3-aminomutase activity
J8Z27_14255	COG1285	pathogenesis
J8Z27_14265	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J8Z27_14275	COG0745	RESPONSE REGULATOR receiver
J8Z27_14280	COG2205	protein histidine kinase activity
J8Z27_14285	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J8Z27_14290	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J8Z27_14295	COG0180	Tryptophanyl-tRNA synthetase
J8Z27_14300	COG0546	phosphoglycolate phosphatase activity
J8Z27_14305	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J8Z27_14310	COG0338	D12 class N6 adenine-specific DNA methyltransferase
J8Z27_14320	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J8Z27_14355	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J8Z27_14365	COG0678	peroxiredoxin activity
J8Z27_14365	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J8Z27_14370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J8Z27_14375	COG0251	oxidation-reduction process
J8Z27_14385	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J8Z27_14385	COG0165	Argininosuccinate lyase
J8Z27_14390	COG0137	argininosuccinate synthase activity
J8Z27_14395	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J8Z27_14400	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J8Z27_14470	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J8Z27_14480	COG4206	TonB-dependent receptor
J8Z27_14500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J8Z27_14505	COG0534	Mate efflux family protein
J8Z27_14515	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J8Z27_14520	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J8Z27_14525	COG2937	Belongs to the GPAT DAPAT family
J8Z27_14530	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
J8Z27_14535	COG3161	chorismate lyase activity
J8Z27_14540	COG1580	Controls the rotational direction of flagella during chemotaxis
J8Z27_14545	COG0705	Rhomboid family
J8Z27_14550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J8Z27_14555	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J8Z27_14560	COG2177	Part of the ABC transporter FtsEX involved in
J8Z27_14565	COG2884	Cell division ATP-binding protein ftsE
J8Z27_14570	COG0552	protein localization to endoplasmic reticulum
J8Z27_14575	COG0742	ribosomal rna small subunit methyltransferase
J8Z27_14585	COG2095	MarC family integral membrane protein
J8Z27_14630	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J8Z27_14635	COG0640	Transcriptional regulator
J8Z27_14640	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J8Z27_14645	COG1280	lysine exporter protein (LysE YggA)
J8Z27_14650	COG2267	carboxylic ester hydrolase activity
J8Z27_14655	COG0561	phosphatase activity
J8Z27_14670	COG3148	PFAM DTW domain containing protein
J8Z27_14675	COG1011	Hydrolase
J8Z27_14690	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J8Z27_14695	COG0019	diaminopimelate decarboxylase activity
J8Z27_14705	COG1965	Belongs to the frataxin family
J8Z27_14710	COG3072	Adenylate cyclase
J8Z27_14715	COG0181	hydroxymethylbilane synthase activity
J8Z27_14720	COG1587	Uroporphyrinogen-III synthase
J8Z27_14725	COG2959	enzyme of heme biosynthesis
J8Z27_14730	COG3071	HemY protein
J8Z27_14765	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
J8Z27_14780	COG3118	belongs to the thioredoxin family
J8Z27_14790	COG0248	Ppx GppA phosphatase
J8Z27_14795	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J8Z27_14805	COG0514	ATP-dependent DNA helicase (RecQ)
J8Z27_14810	COG2962	Rard protein
J8Z27_14820	COG1280	lysine exporter protein (LysE YggA)
J8Z27_14825	COG0405	Gamma-glutamyltransferase
J8Z27_14830	COG0210	DNA helicase
J8Z27_14840	COG3220	belongs to the UPF0276 family
J8Z27_14860	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J8Z27_14865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J8Z27_14880	COG0644	oxidoreductase
J8Z27_14890	COG3527	Alpha-acetolactate decarboxylase
J8Z27_14905	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J8Z27_14910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J8Z27_14920	COG2207	Transcriptional regulator
J8Z27_14925	COG3537	Alpha-1,2-mannosidase
J8Z27_14935	COG3537	Alpha-1,2-mannosidase
J8Z27_14940	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J8Z27_14945	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J8Z27_14945	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J8Z27_14945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J8Z27_14965	COG0477	Major facilitator Superfamily
J8Z27_14985	COG2197	response regulator
J8Z27_15000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J8Z27_15005	COG0601	transmembrane transport
J8Z27_15050	COG0210	DNA helicase
J8Z27_15055	COG1309	transcriptional regulator
J8Z27_15060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J8Z27_15065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J8Z27_15070	COG2960	long-chain fatty acid transporting porin activity
J8Z27_15075	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J8Z27_15080	COG0583	DNA-binding transcription factor activity
J8Z27_15085	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J8Z27_15115	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J8Z27_15115	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J8Z27_15130	COG0084	hydrolase, TatD family'
J8Z27_15135	COG0805	protein transport
J8Z27_15140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J8Z27_15145	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J8Z27_15150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J8Z27_15160	COG2226	methyltransferase
J8Z27_15165	COG1322	Protein conserved in bacteria
J8Z27_15175	COG1639	'signal transduction protein
J8Z27_15195	COG2081	HI0933 family
J8Z27_15205	COG1528	Iron-storage protein
J8Z27_15210	COG0589	response to stress
J8Z27_15225	COG0742	ribosomal rna small subunit methyltransferase
J8Z27_15230	COG5001	Diguanylate cyclase
J8Z27_15230	COG5002	protein histidine kinase activity
J8Z27_15235	COG1522	sequence-specific DNA binding
J8Z27_15255	COG0006	proline dipeptidase activity
J8Z27_15255	COG0006	proline dipeptidase activity
J8Z27_15265	COG2022	thiamine diphosphate biosynthetic process
J8Z27_15275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J8Z27_15280	COG0352	thiamine-phosphate diphosphorylase activity
J8Z27_15295	COG2132	Multicopper oxidase
J8Z27_15340	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J8Z27_15345	COG1739	Uncharacterized protein family UPF0029
J8Z27_15355	COG0183	Belongs to the thiolase family
J8Z27_15360	COG0583	DNA-binding transcription factor activity
J8Z27_15365	COG2814	Major facilitator Superfamily
J8Z27_15375	COG0765	amino acid transport
J8Z27_15385	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J8Z27_15390	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J8Z27_15395	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J8Z27_15400	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J8Z27_15405	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J8Z27_15410	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J8Z27_15425	COG3312	ion transport
J8Z27_15430	COG1475	DNA binding
J8Z27_15435	COG1192	Involved in chromosome partitioning
J8Z27_15440	COG0357	Ribosomal RNA small subunit methyltransferase G
J8Z27_15445	COG0445	tRNA wobble uridine modification
J8Z27_15450	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J8Z27_15460	COG0706	membrane insertase activity
J8Z27_15475	COG0230	Belongs to the bacterial ribosomal protein bL34 family
J8Z27_15480	COG1126	abc transporter atp-binding protein
J8Z27_15505	COG1444	tRNA N-acetyltransferase activity
J8Z27_15520	COG0643	Histidine kinase
J8Z27_15520	COG2198	Histidine kinase
J8Z27_15530	COG0835	chemotaxis
J8Z27_15535	COG0840	transmembrane signaling receptor activity
J8Z27_15540	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J8Z27_15590	COG0583	DNA-binding transcription factor activity
J8Z27_15595	COG1175	transmembrane transport
J8Z27_15615	COG0546	phosphoglycolate phosphatase activity
J8Z27_15620	COG3842	ATPase activity
J8Z27_15625	COG0589	response to stress
J8Z27_15630	COG2723	6-phospho-beta-galactosidase activity
J8Z27_15660	COG0583	DNA-binding transcription factor activity
J8Z27_15675	COG0351	phosphomethylpyrimidine kinase
J8Z27_15680	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J8Z27_15695	COG4977	sequence-specific DNA binding
J8Z27_15710	COG0671	phosphoesterase, PA-phosphatase related
J8Z27_15755	COG0697	spore germination
J8Z27_15790	COG0471	metal ion transport
J8Z27_15800	COG2814	Major facilitator Superfamily
J8Z27_15805	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J8Z27_15845	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
J8Z27_15860	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
J8Z27_15870	COG2207	Transcriptional regulator
J8Z27_15885	COG4999	Histidine kinase
J8Z27_15885	COG2205	protein histidine kinase activity
J8Z27_15885	COG3437	response regulator, receiver
J8Z27_15885	COG3850	Histidine kinase
J8Z27_15890	COG0402	S-adenosylhomocysteine deaminase activity
J8Z27_15900	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J8Z27_15910	COG2186	Transcriptional regulator
J8Z27_15920	COG0402	S-adenosylhomocysteine deaminase activity
J8Z27_15925	COG1404	Belongs to the peptidase S8 family
J8Z27_15955	COG0456	acetyltransferase
J8Z27_15970	COG2909	trisaccharide binding
J8Z27_15975	COG0058	SHG alpha-glucan phosphorylase activity
J8Z27_15980	COG1640	4-alpha-glucanotransferase
J8Z27_15985	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J8Z27_16005	COG1472	Belongs to the glycosyl hydrolase 3 family
J8Z27_16010	COG3876	Protein conserved in bacteria
J8Z27_16025	COG3293	Transposase
J8Z27_16075	COG0561	phosphatase activity
J8Z27_16095	COG0488	(ABC) transporter
J8Z27_16120	COG1733	regulation of RNA biosynthetic process
J8Z27_16125	COG0456	acetyltransferase
J8Z27_16130	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J8Z27_16135	COG0662	Cupin 2, conserved barrel domain protein
J8Z27_16140	COG0527	aspartate kinase activity
J8Z27_16160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J8Z27_16160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J8Z27_16160	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
J8Z27_16165	COG0383	alpha-mannosidase activity
J8Z27_16175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J8Z27_16175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J8Z27_16175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J8Z27_16200	COG0113	porphobilinogen synthase activity
J8Z27_16205	COG0183	Belongs to the thiolase family
J8Z27_16215	COG3246	L-lysine catabolic process to acetate
J8Z27_16245	COG0583	DNA-binding transcription factor activity
J8Z27_16250	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J8Z27_16260	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J8Z27_16265	COG2205	protein histidine kinase activity
J8Z27_16265	COG3437	response regulator, receiver
J8Z27_16265	COG3850	Histidine kinase
J8Z27_16265	COG4999	Histidine kinase
J8Z27_16275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J8Z27_16305	COG0657	acetylesterase activity
J8Z27_16315	COG4175	Glycine betaine
J8Z27_16315	COG3448	diguanylate cyclase activity
J8Z27_16320	COG4176	ABC-type proline glycine betaine transport system permease component
J8Z27_16340	COG2095	MarC family integral membrane protein
J8Z27_16350	COG0583	DNA-binding transcription factor activity
J8Z27_16375	COG4964	Belongs to the GSP D family
J8Z27_16385	COG2894	cell division
J8Z27_16440	COG1477	protein flavinylation
J8Z27_16455	COG0840	transmembrane signaling receptor activity
J8Z27_16465	COG0573	inorganic phosphate transmembrane transporter activity
J8Z27_16470	COG0581	inorganic phosphate transmembrane transporter activity
J8Z27_16475	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J8Z27_16490	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
J8Z27_16495	COG1162	GTPase activity
J8Z27_16505	COG0363	glucosamine-6-phosphate deaminase activity
J8Z27_16525	COG0454	-acetyltransferase
J8Z27_16550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Z27_16560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J8Z27_16565	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J8Z27_16570	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
J8Z27_16585	COG3655	Transcriptional regulator
J8Z27_16595	COG0137	argininosuccinate synthase activity
J8Z27_16610	COG3608	succinylglutamate desuccinylase aspartoacylase
J8Z27_16630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J8Z27_16640	COG3314	Sporulation integral membrane protein YlbJ
J8Z27_16645	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J8Z27_16650	COG1151	hydroxylamine reductase activity
J8Z27_16660	COG0583	DNA-binding transcription factor activity
J8Z27_16675	COG3604	Transcriptional regulator
J8Z27_16705	COG3046	protein related to deoxyribodipyrimidine photolyase
J8Z27_16715	COG2329	Antibiotic biosynthesis monooxygenase
J8Z27_16720	COG3304	Inner membrane component domain
J8Z27_16730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J8Z27_16785	COG0004	ammonium transporteR
J8Z27_16795	COG3383	formate dehydrogenase (NAD+) activity
J8Z27_16805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J8Z27_16825	COG0739	heme binding
J8Z27_16830	COG3047	cAMP biosynthetic process
J8Z27_16870	COG2271	Major facilitator Superfamily
J8Z27_16875	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J8Z27_16895	COG0431	NADPH-dependent FMN reductase
J8Z27_16900	COG0697	spore germination
J8Z27_16925	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J8Z27_16925	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J8Z27_16930	COG2207	Transcriptional regulator
J8Z27_16930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J8Z27_16935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J8Z27_16940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J8Z27_16950	COG1522	sequence-specific DNA binding
J8Z27_16960	COG0840	transmembrane signaling receptor activity
J8Z27_16970	COG1357	PFAM Pentapeptide repeats (8 copies)
J8Z27_16990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J8Z27_17005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J8Z27_17015	COG1309	transcriptional regulator
J8Z27_17030	COG0745	RESPONSE REGULATOR receiver
J8Z27_17035	COG5002	protein histidine kinase activity
J8Z27_17095	COG1054	Belongs to the UPF0176 family
J8Z27_17110	COG1028	Short-chain dehydrogenase reductase Sdr
J8Z27_17135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J8Z27_17145	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J8Z27_17165	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J8Z27_17175	COG1733	regulation of RNA biosynthetic process
J8Z27_17190	COG3795	YCII-related domain
J8Z27_17195	COG4941	Belongs to the sigma-70 factor family
J8Z27_17200	COG0625	glutathione transferase activity
J8Z27_17205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J8Z27_17210	COG0366	Alpha amylase catalytic
J8Z27_17230	COG2084	Dehydrogenase
J8Z27_17245	COG2130	NADP-dependent
J8Z27_17250	COG1309	transcriptional regulator
J8Z27_17265	COG3097	Belongs to the UPF0267 family
J8Z27_17270	COG0513	Belongs to the DEAD box helicase family
J8Z27_17280	COG1228	amidohydrolase
J8Z27_17305	COG1175	transmembrane transport
J8Z27_17310	COG0395	ABC-type sugar transport system, permease component
J8Z27_17315	COG1554	hydrolase, family 65, central catalytic
J8Z27_17320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J8Z27_17325	COG3842	ATPase activity
J8Z27_17335	COG1621	beta-fructofuranosidase activity
J8Z27_17345	COG1609	Transcriptional regulator
J8Z27_17370	COG3842	ATPase activity
J8Z27_17375	COG1472	Belongs to the glycosyl hydrolase 3 family
J8Z27_17390	COG0110	maltose O-acetyltransferase activity
J8Z27_17415	COG2356	endonuclease I
J8Z27_17430	COG0564	pseudouridine synthase activity
J8Z27_17450	COG0583	DNA-binding transcription factor activity
J8Z27_17455	COG2814	Major facilitator Superfamily
J8Z27_17480	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J8Z27_17490	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J8Z27_17495	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J8Z27_17500	COG0579	oxidoreductase
J8Z27_17520	COG1012	belongs to the aldehyde dehydrogenase family
J8Z27_17525	COG3284	Transcriptional regulator
J8Z27_17550	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J8Z27_17555	COG0363	glucosamine-6-phosphate deaminase activity
J8Z27_17560	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J8Z27_17565	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J8Z27_17575	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J8Z27_17585	COG2271	Major facilitator Superfamily
J8Z27_17590	COG3851	Histidine kinase
J8Z27_17595	COG2197	response regulator
J8Z27_17615	COG0418	dihydroorotase activity
J8Z27_17620	COG3217	Mosc domain protein beta barrel domain protein
J8Z27_17620	COG3217	Mosc domain protein beta barrel domain protein
J8Z27_17620	COG0633	Ferredoxin
J8Z27_17620	COG0633	Ferredoxin
J8Z27_17630	COG1349	DNA-binding transcription factor activity
J8Z27_17650	COG2354	Protein conserved in bacteria
J8Z27_17660	COG0366	Alpha amylase catalytic
J8Z27_17685	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J8Z27_17700	COG0739	heme binding
J8Z27_17715	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
J8Z27_17720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J8Z27_17730	COG0848	biopolymer transport protein
J8Z27_17735	COG0811	peptide transport
J8Z27_17740	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
J8Z27_17750	COG3721	Heme iron utilization protein
J8Z27_17755	COG0748	coenzyme F420 binding
J8Z27_17760	COG2096	Adenosyltransferase
J8Z27_17765	COG3842	ATPase activity
J8Z27_17775	COG1175	transmembrane transport
J8Z27_17780	COG3833	ABC-type maltose transport systems, permease component
J8Z27_17790	COG4533	DNA binding
J8Z27_17830	COG0784	Response regulator, receiver
J8Z27_17830	COG2205	protein histidine kinase activity
J8Z27_17830	COG5002	protein histidine kinase activity
J8Z27_17840	COG0861	Integral membrane protein TerC family
J8Z27_17845	COG0402	S-adenosylhomocysteine deaminase activity
J8Z27_17850	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J8Z27_17855	COG1566	PFAM secretion protein HlyD family protein
J8Z27_17880	COG0745	RESPONSE REGULATOR receiver
J8Z27_17900	COG0121	glutamine amidotransferase
J8Z27_17905	COG0531	amino acid
J8Z27_17925	COG0673	inositol 2-dehydrogenase activity
J8Z27_17930	COG1765	OsmC-like protein
J8Z27_17935	COG3385	transposase activity
J8Z27_17940	COG0110	maltose O-acetyltransferase activity
J8Z27_17965	COG2304	oxidoreductase activity
J8Z27_17970	COG2304	oxidoreductase activity
J8Z27_17985	COG0714	Associated with various cellular activities
J8Z27_18010	COG5002	protein histidine kinase activity
J8Z27_18015	COG0745	RESPONSE REGULATOR receiver
J8Z27_18025	COG0745	RESPONSE REGULATOR receiver
J8Z27_18030	COG2205	protein histidine kinase activity
J8Z27_18035	COG4452	Inner membrane protein CreD
J8Z27_18040	COG0346	lactoylglutathione lyase activity
J8Z27_18050	COG0156	8-amino-7-oxononanoate synthase activity
J8Z27_18055	COG1063	alcohol dehydrogenase
J8Z27_18070	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J8Z27_18075	COG2195	Cleaves the N-terminal amino acid of tripeptides
J8Z27_18100	COG0784	Response regulator, receiver
J8Z27_18100	COG2205	protein histidine kinase activity
J8Z27_18105	COG2205	protein histidine kinase activity
J8Z27_18105	COG0784	Response regulator, receiver
J8Z27_18110	COG0784	Response regulator, receiver
J8Z27_18110	COG5002	protein histidine kinase activity
J8Z27_18110	COG2205	protein histidine kinase activity
J8Z27_18125	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J8Z27_18130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J8Z27_18135	COG3186	Phenylalanine-4-hydroxylase
J8Z27_18175	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J8Z27_18180	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J8Z27_18205	COG1454	alcohol dehydrogenase
J8Z27_18210	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
J8Z27_18225	COG1011	Hydrolase
J8Z27_18255	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J8Z27_18260	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J8Z27_18265	COG1840	ABC-type Fe3 transport system, periplasmic component
J8Z27_18270	COG3842	ATPase activity
J8Z27_18295	COG2866	Carboxypeptidase
J8Z27_18300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J8Z27_18305	COG0583	DNA-binding transcription factor activity
J8Z27_18310	COG1760	l-serine dehydratase
J8Z27_18330	COG3706	GGDEF domain
J8Z27_18335	COG0835	chemotaxis
J8Z27_18335	COG0784	Response regulator, receiver
J8Z27_18340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J8Z27_18360	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
J8Z27_18365	COG0494	nUDIX hydrolase
J8Z27_18370	COG0714	Associated with various cellular activities
J8Z27_18375	COG2425	protein containing a von Willebrand factor type A (vWA) domain
J8Z27_18395	COG3706	GGDEF domain
J8Z27_18400	COG1846	Transcriptional regulator
J8Z27_18405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J8Z27_18430	COG3048	D-serine ammonia-lyase activity
J8Z27_18450	COG0814	amino acid
J8Z27_18460	COG0513	Belongs to the DEAD box helicase family
J8Z27_18465	COG0840	transmembrane signaling receptor activity
J8Z27_18470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J8Z27_18475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J8Z27_18490	COG0546	phosphoglycolate phosphatase activity
J8Z27_18505	COG0243	molybdopterin cofactor binding
J8Z27_18510	COG1648	precorrin-2 dehydrogenase activity
J8Z27_18510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J8Z27_18515	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J8Z27_18525	COG1116	anion transmembrane transporter activity
J8Z27_18525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J8Z27_18530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J8Z27_18535	COG1116	anion transmembrane transporter activity
J8Z27_18540	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J8Z27_18540	COG2146	nitrite reductase [NAD(P)H] activity
J8Z27_18545	COG2146	nitrite reductase [NAD(P)H] activity
J8Z27_18550	COG1858	cytochrome C peroxidase
J8Z27_18575	COG3118	belongs to the thioredoxin family
J8Z27_18580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J8Z27_18585	COG0420	3'-5' exonuclease activity
J8Z27_18590	COG0419	ATPase involved in DNA repair
J8Z27_18595	COG0784	Response regulator, receiver
J8Z27_18595	COG2205	protein histidine kinase activity
J8Z27_18600	COG0156	8-amino-7-oxononanoate synthase activity
J8Z27_18610	COG0038	chloride channel
J8Z27_18615	COG0523	cobalamin synthesis protein
J8Z27_18620	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J8Z27_18645	COG1522	sequence-specific DNA binding
J8Z27_18650	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J8Z27_18655	COG1072	(Pantothenic acid kinase))
J8Z27_18665	COG1063	alcohol dehydrogenase
J8Z27_18670	COG2213	PTS system mannitol-specific
J8Z27_18675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J8Z27_18680	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J8Z27_18685	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J8Z27_18695	COG0583	DNA-binding transcription factor activity
J8Z27_18710	COG2897	thiosulfate sulfurtransferase activity
J8Z27_18715	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J8Z27_18730	COG0513	Belongs to the DEAD box helicase family
J8Z27_18735	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J8Z27_18735	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J8Z27_18765	COG3293	Transposase
J8Z27_18770	COG0800	Aldolase
J8Z27_18775	COG1803	Methylglyoxal synthase
J8Z27_18780	COG1879	ABC-type sugar transport system periplasmic component
J8Z27_18785	COG2205	protein histidine kinase activity
J8Z27_18785	COG2198	Histidine kinase
J8Z27_18785	COG0784	Response regulator, receiver
J8Z27_18795	COG1979	alcohol dehydrogenase
J8Z27_18800	COG2207	Transcriptional regulator
J8Z27_18805	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J8Z27_18815	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J8Z27_18815	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J8Z27_18815	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
J8Z27_18820	COG1105	Belongs to the carbohydrate kinase PfkB family
J8Z27_18825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J8Z27_18825	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J8Z27_18830	COG1609	Transcriptional regulator
J8Z27_18845	COG1492	cobalamin metabolic process
J8Z27_18850	COG0725	ABC transporter, periplasmic molybdate-binding protein
J8Z27_18855	COG4149	molybdate abc transporter
J8Z27_18860	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
J8Z27_18870	COG3706	GGDEF domain
J8Z27_18870	COG5001	Diguanylate cyclase
J8Z27_18870	COG4251	negative regulation of phosphorylation
J8Z27_18870	COG2203	Gaf domain
J8Z27_18875	COG3706	GGDEF domain
J8Z27_18890	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J8Z27_18895	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
J8Z27_18905	COG0745	RESPONSE REGULATOR receiver
J8Z27_18920	COG3140	Belongs to the UPF0181 family
J8Z27_18935	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J8Z27_18975	COG0023	Translation Initiation Factor
J8Z27_18995	COG3266	domain, Protein
J8Z27_19000	COG0045	succinate-CoA ligase (ADP-forming) activity
J8Z27_19000	COG1042	CoA-binding domain protein
J8Z27_19000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Z27_19005	COG0583	DNA-binding transcription factor activity
J8Z27_19010	COG1629	transport
J8Z27_19010	COG4771	TonB-dependent receptor
J8Z27_19015	COG0840	transmembrane signaling receptor activity
J8Z27_19035	COG3706	GGDEF domain
J8Z27_19055	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
J8Z27_19060	COG1028	Short-chain dehydrogenase reductase Sdr
J8Z27_19070	COG1024	Enoyl-CoA hydratase
J8Z27_19075	COG1024	Enoyl-CoA hydratase
J8Z27_19090	COG0183	Belongs to the thiolase family
J8Z27_19100	COG1960	acyl-CoA dehydrogenase activity
J8Z27_19105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J8Z27_19110	COG1024	Enoyl-CoA hydratase
J8Z27_19140	COG2259	Doxx family
J8Z27_19145	COG1741	Belongs to the pirin family
J8Z27_19155	COG1115	amino acid carrier protein
J8Z27_19160	COG0583	DNA-binding transcription factor activity
J8Z27_19165	COG2910	NAD(P)H-binding
J8Z27_19200	COG1132	(ABC) transporter
J8Z27_19205	COG1129	ABC transporter
J8Z27_19225	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J8Z27_19230	COG3300	MHYT domain
J8Z27_19230	COG5001	Diguanylate cyclase
J8Z27_19235	COG0789	Transcriptional regulator
J8Z27_19245	COG2176	DNA-directed DNA polymerase activity
J8Z27_19255	COG4533	DNA binding
J8Z27_19265	COG2050	protein possibly involved in aromatic compounds catabolism
J8Z27_19305	COG0737	Belongs to the 5'-nucleotidase family
J8Z27_19310	COG3593	DNA synthesis involved in DNA repair
J8Z27_19320	COG0583	DNA-binding transcription factor activity
J8Z27_19325	COG2116	formate transmembrane transporter activity
J8Z27_19330	COG2353	YceI-like domain
J8Z27_19335	COG3038	cytochrome b561
J8Z27_19355	COG3069	C4-dicarboxylate transmembrane transporter activity
J8Z27_19360	COG2197	response regulator
J8Z27_19365	COG3850	Histidine kinase
J8Z27_19370	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J8Z27_19380	COG0243	molybdopterin cofactor binding
J8Z27_19400	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J8Z27_19405	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
J8Z27_19415	COG1984	allophanate hydrolase subunit 2
J8Z27_19425	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
J8Z27_19430	COG4181	ATPase activity
J8Z27_19440	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J8Z27_19445	COG1716	ATPase activity
J8Z27_19445	COG5001	Diguanylate cyclase
J8Z27_19455	COG0484	heat shock protein binding
J8Z27_19470	COG1324	tolerance protein
J8Z27_19475	COG0210	DNA helicase
J8Z27_19480	COG1289	transmembrane transporter activity
J8Z27_19500	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J8Z27_19525	COG2827	Endonuclease containing a URI domain
J8Z27_19530	COG3132	Protein of unknown function, DUF480
J8Z27_19540	COG2926	Belongs to the UPF0265 family
J8Z27_19550	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J8Z27_19555	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J8Z27_19560	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J8Z27_19570	COG0247	lactate metabolic process
J8Z27_19590	COG0545	Peptidyl-prolyl cis-trans isomerase
J8Z27_19600	COG4067	protein conserved in archaea
J8Z27_19600	COG0189	ligase activity
J8Z27_19610	COG0602	queuosine metabolic process
J8Z27_19615	COG1328	CTP reductase activity
J8Z27_19650	COG3240	lipase activity
J8Z27_19655	COG2814	Major facilitator Superfamily
J8Z27_19660	COG1794	racemase activity, acting on amino acids and derivatives
J8Z27_19675	COG0183	Belongs to the thiolase family
J8Z27_19685	COG1309	transcriptional regulator
J8Z27_19725	COG1522	sequence-specific DNA binding
J8Z27_19760	COG2815	serine threonine protein kinase
J8Z27_19760	COG0515	serine threonine protein kinase
J8Z27_19785	COG3501	Rhs element vgr protein
J8Z27_19830	COG0739	heme binding
J8Z27_19840	COG0840	transmembrane signaling receptor activity
J8Z27_19865	COG2759	Belongs to the formate--tetrahydrofolate ligase family
J8Z27_19895	COG4172	Belongs to the ABC transporter superfamily
J8Z27_19900	COG4239	(ABC) transporter, permease
J8Z27_19905	COG4174	ABC transporter (Permease)
J8Z27_19910	COG4166	transmembrane transport
J8Z27_19920	COG0840	transmembrane signaling receptor activity
J8Z27_19925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J8Z27_19930	COG1067	ATP-dependent peptidase activity
J8Z27_19940	COG4172	Belongs to the ABC transporter superfamily
J8Z27_19945	COG0583	DNA-binding transcription factor activity
J8Z27_19950	COG1620	l-lactate permease
J8Z27_19955	COG1304	FMN binding
J8Z27_19970	COG4175	Glycine betaine
J8Z27_19970	COG3448	diguanylate cyclase activity
J8Z27_19990	COG1012	belongs to the aldehyde dehydrogenase family
J8Z27_19995	COG1309	transcriptional regulator
J8Z27_20005	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J8Z27_20010	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J8Z27_20025	COG2200	EAL domain
J8Z27_20030	COG2207	Transcriptional regulator
J8Z27_20035	COG2814	Major facilitator Superfamily
J8Z27_20040	COG0583	DNA-binding transcription factor activity
J8Z27_20045	COG3394	polysaccharide catabolic process
J8Z27_20050	COG0633	Ferredoxin
J8Z27_20050	COG3217	Mosc domain protein beta barrel domain protein
J8Z27_20055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J8Z27_20055	COG2205	protein histidine kinase activity
J8Z27_20065	COG0657	acetylesterase activity
J8Z27_20075	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
J8Z27_20075	COG0674	pyruvate-flavodoxin oxidoreductase activity
J8Z27_20080	COG1013	pyruvate-flavodoxin oxidoreductase activity
J8Z27_20105	COG2197	response regulator
J8Z27_20120	COG0516	GMP reductase activity
J8Z27_20125	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J8Z27_20125	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J8Z27_20140	COG3437	response regulator, receiver
J8Z27_20145	COG4999	Histidine kinase
J8Z27_20145	COG2205	protein histidine kinase activity
J8Z27_20145	COG3437	response regulator, receiver
J8Z27_20145	COG3850	Histidine kinase
J8Z27_20155	COG2172	sigma factor antagonist activity
J8Z27_20165	COG1366	Belongs to the anti-sigma-factor antagonist family
J8Z27_20170	COG0840	transmembrane signaling receptor activity
J8Z27_20190	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
J8Z27_20195	COG0513	Belongs to the DEAD box helicase family
J8Z27_20205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J8Z27_20205	COG4191	Histidine kinase
J8Z27_20210	COG0784	Response regulator, receiver
J8Z27_20210	COG3437	response regulator, receiver
J8Z27_20215	COG1609	Transcriptional regulator
J8Z27_20220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J8Z27_20230	COG1172	Belongs to the binding-protein-dependent transport system permease family
J8Z27_20235	COG1129	ABC transporter
J8Z27_20240	COG1869	D-ribose catabolic process
J8Z27_20260	COG0004	ammonium transporteR
J8Z27_20285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J8Z27_20335	COG1609	Transcriptional regulator
J8Z27_20340	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J8Z27_20345	COG3265	gluconokinase activity
J8Z27_20350	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J8Z27_20350	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J8Z27_20360	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J8Z27_20390	COG5001	Diguanylate cyclase
J8Z27_20400	COG3123	guanosine phosphorylase activity
J8Z27_20410	COG0668	transmembrane transport
J8Z27_20430	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J8Z27_20470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J8Z27_20475	COG4232	protein-disulfide reductase activity
J8Z27_20490	COG1280	lysine exporter protein (LysE YggA)
J8Z27_20520	COG0443	Heat shock 70 kDa protein
J8Z27_20525	COG0583	DNA-binding transcription factor activity
J8Z27_20535	COG4948	Mandelate Racemase Muconate Lactonizing
J8Z27_20540	COG1396	sequence-specific DNA binding
J8Z27_20545	COG5001	Diguanylate cyclase
J8Z27_20550	COG0683	leucine binding
J8Z27_20555	COG3706	GGDEF domain
J8Z27_20570	COG1523	belongs to the glycosyl hydrolase 13 family
J8Z27_20590	COG3279	Response regulator of the LytR AlgR family
J8Z27_20595	COG3275	phosphorelay sensor kinase activity
J8Z27_20610	COG4591	ABC-type transport system involved in lipoprotein release permease component
J8Z27_20615	COG1136	(ABC) transporter
J8Z27_20650	COG2249	NAD(P)H dehydrogenase (quinone) activity
J8Z27_20660	COG0583	DNA-binding transcription factor activity
J8Z27_20670	COG3530	Putative quorum-sensing-regulated virulence factor
J8Z27_20685	COG1686	Belongs to the peptidase S11 family
J8Z27_20700	COG3036	rescue of stalled ribosome
J8Z27_20705	COG1278	Cold shock
J8Z27_20720	COG1017	nitric oxide dioxygenase activity
J8Z27_20720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J8Z27_20725	COG3604	Transcriptional regulator
J8Z27_20740	COG2249	NAD(P)H dehydrogenase (quinone) activity
J8Z27_20750	COG0534	Mate efflux family protein
J8Z27_20755	COG0697	spore germination
J8Z27_20775	COG0583	DNA-binding transcription factor activity
J8Z27_20780	COG5001	Diguanylate cyclase
J8Z27_20815	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J8Z27_20825	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J8Z27_20830	COG0509	glycine decarboxylation via glycine cleavage system
J8Z27_20865	COG1132	(ABC) transporter
J8Z27_20870	COG0589	response to stress
J8Z27_20880	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J8Z27_20880	COG2111	Na H antiporter
J8Z27_20885	COG1006	Multisubunit Na H antiporter MnhC subunit
J8Z27_20890	COG0651	ATP synthesis coupled electron transport
J8Z27_20895	COG1863	multisubunit Na H antiporter MnhE subunit
J8Z27_20900	COG2212	antiporter activity
J8Z27_20905	COG1320	monovalent cation:proton antiporter activity
J8Z27_20930	COG0673	inositol 2-dehydrogenase activity
J8Z27_20945	COG5553	Cysteine dioxygenase type I
J8Z27_20950	COG0840	transmembrane signaling receptor activity
J8Z27_20955	COG0840	transmembrane signaling receptor activity
J8Z27_20995	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
J8Z27_21005	COG0438	transferase activity, transferring glycosyl groups
J8Z27_21015	COG1045	serine acetyltransferase
J8Z27_21030	COG0438	transferase activity, transferring glycosyl groups
J8Z27_21035	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
J8Z27_21040	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J8Z27_21045	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J8Z27_21050	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J8Z27_21060	COG4989	oxidoreductase activity
J8Z27_21070	COG0366	Alpha amylase catalytic
J8Z27_21080	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J8Z27_21085	COG1126	abc transporter atp-binding protein
J8Z27_21090	COG0765	amino acid transport
J8Z27_21095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J8Z27_21100	COG0765	amino acid transport
J8Z27_21105	COG0109	protoheme IX farnesyltransferase activity
J8Z27_21110	COG1612	heme a metabolic process
J8Z27_21135	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
J8Z27_21140	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J8Z27_21145	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J8Z27_21150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J8Z27_21165	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
J8Z27_21170	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J8Z27_21170	COG0574	Belongs to the PEP-utilizing enzyme family
J8Z27_21175	COG3314	Sporulation integral membrane protein YlbJ
J8Z27_21185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J8Z27_21210	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J8Z27_21225	COG1741	Belongs to the pirin family
J8Z27_21270	COG2205	protein histidine kinase activity
J8Z27_21275	COG0745	RESPONSE REGULATOR receiver
J8Z27_21300	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J8Z27_21310	COG0523	cobalamin synthesis protein
J8Z27_21315	COG2988	succinylglutamate desuccinylase activity
J8Z27_21325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J8Z27_21330	COG2423	ornithine cyclodeaminase activity
J8Z27_21340	COG3938	Belongs to the proline racemase family
J8Z27_21350	COG2186	Transcriptional regulator
J8Z27_21365	COG0601	transmembrane transport
J8Z27_21370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J8Z27_21385	COG0006	proline dipeptidase activity
J8Z27_21405	COG4934	collagen metabolic process
J8Z27_21415	COG3568	Endonuclease Exonuclease Phosphatase
J8Z27_21425	COG3291	Pkd domain containing protein
J8Z27_21430	COG0513	Belongs to the DEAD box helicase family
J8Z27_21440	COG1388	LysM domain
J8Z27_21440	COG1376	ErfK ybiS ycfS ynhG family protein
J8Z27_21445	COG0415	Belongs to the DNA photolyase family
J8Z27_21450	COG0789	Transcriptional regulator
J8Z27_21455	COG3272	Protein of unknown function (DUF1722)
J8Z27_21460	COG0813	purine-nucleoside phosphorylase activity
J8Z27_21490	COG1566	PFAM secretion protein HlyD family protein
J8Z27_21495	COG0786	glutamate:sodium symporter activity
J8Z27_21510	COG1132	(ABC) transporter
J8Z27_21560	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J8Z27_21570	COG0259	pyridoxamine-phosphate oxidase activity
J8Z27_21600	COG3033	Beta-eliminating lyase
J8Z27_21605	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
J8Z27_21610	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J8Z27_21615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Z27_21625	COG1999	signal sequence binding
J8Z27_21640	COG1671	Belongs to the UPF0178 family
J8Z27_21645	COG0393	Putative heavy-metal-binding
J8Z27_21650	COG0583	DNA-binding transcription factor activity
J8Z27_21655	COG2814	Major facilitator Superfamily
J8Z27_21665	COG0584	glycerophosphoryl diester phosphodiesterase
J8Z27_21670	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J8Z27_21680	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J8Z27_21705	COG3527	Alpha-acetolactate decarboxylase
J8Z27_21710	COG2814	Major facilitator Superfamily
J8Z27_21715	COG0028	Belongs to the TPP enzyme family
J8Z27_21875	COG1301	dicarboxylic acid transport
J8Z27_21880	COG0840	transmembrane signaling receptor activity
J8Z27_21895	COG4266	Belongs to the allantoicase family
J8Z27_21915	COG2252	PERMEase
J8Z27_21930	COG3214	Protein conserved in bacteria
J8Z27_21945	COG2205	protein histidine kinase activity
J8Z27_21995	COG0109	protoheme IX farnesyltransferase activity
J8Z27_22000	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J8Z27_22005	COG1845	cytochrome c oxidase, subunit III
J8Z27_22010	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J8Z27_22015	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J8Z27_22020	COG2706	6-phosphogluconolactonase activity
J8Z27_22040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J8Z27_22055	COG0459	protein refolding
J8Z27_22060	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J8Z27_22065	COG0071	Belongs to the small heat shock protein (HSP20) family
J8Z27_22070	COG0628	permease
J8Z27_22105	COG0668	transmembrane transport
J8Z27_22110	COG1597	lipid kinase activity
J8Z27_22110	COG1803	Methylglyoxal synthase
J8Z27_22140	COG5002	protein histidine kinase activity
J8Z27_22140	COG5001	Diguanylate cyclase
J8Z27_22160	COG2084	Dehydrogenase
J8Z27_22165	COG3622	Belongs to the hyi family
J8Z27_22170	COG3960	tartronate-semialdehyde synthase activity
J8Z27_22175	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J8Z27_22185	COG0583	DNA-binding transcription factor activity
J8Z27_22190	COG1288	antiporter activity
J8Z27_22200	COG1846	Transcriptional regulator
J8Z27_22205	COG0697	spore germination
J8Z27_22210	COG1028	Short-chain dehydrogenase reductase Sdr
J8Z27_22260	COG1192	Involved in chromosome partitioning
J8Z27_22370	COG2200	EAL domain
J8Z27_22410	COG3070	regulator of competence-specific genes
J8Z27_22530	COG3119	arylsulfatase activity
J8Z27_22905	COG1475	DNA binding
J8Z27_22950	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J8Z27_23130	COG0433	COG0433 Predicted ATPase
J8Z27_23140	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J8Z27_23145	COG0210	DNA helicase