locus-tag	class	description
VspSTUT16_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
VspSTUT16_00020	COG0592	DNA-directed DNA polymerase activity
VspSTUT16_00040	COG0187	DNA topoisomerase II activity
VspSTUT16_00070	COG0071	Belongs to the small heat shock protein (HSP20) family
VspSTUT16_00080	COG3977	Valine--pyruvate aminotransferase
VspSTUT16_00090	COG0366	Alpha amylase catalytic
VspSTUT16_00100	COG0751	glycine-tRNA ligase activity
VspSTUT16_00120	COG2119	membrane
VspSTUT16_00140	COG0425	Belongs to the sulfur carrier protein TusA family
VspSTUT16_00170	COG0604	alcohol dehydrogenase
VspSTUT16_00180	COG0183	Belongs to the thiolase family
VspSTUT16_00200	COG1739	Uncharacterized protein family UPF0029
VspSTUT16_00210	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VspSTUT16_00230	COG2132	Multicopper oxidase
VspSTUT16_00240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
VspSTUT16_00270	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VspSTUT16_00280	COG2104	thiamine diphosphate biosynthetic process
VspSTUT16_00310	COG0006	proline dipeptidase activity
VspSTUT16_00310	COG0006	proline dipeptidase activity
VspSTUT16_00370	COG3220	belongs to the UPF0276 family
VspSTUT16_00390	COG0210	DNA helicase
VspSTUT16_00400	COG0405	Gamma-glutamyltransferase
VspSTUT16_00410	COG1280	lysine exporter protein (LysE YggA)
VspSTUT16_00430	COG2962	Rard protein
VspSTUT16_00440	COG0514	ATP-dependent DNA helicase (RecQ)
VspSTUT16_00460	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
VspSTUT16_00470	COG0248	Ppx GppA phosphatase
VspSTUT16_00480	COG0513	Belongs to the DEAD box helicase family
VspSTUT16_00490	COG3118	belongs to the thioredoxin family
VspSTUT16_00520	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
VspSTUT16_00530	COG0633	Ferredoxin
VspSTUT16_00550	COG3071	HemY protein
VspSTUT16_00560	COG2959	enzyme of heme biosynthesis
VspSTUT16_00570	COG1587	Uroporphyrinogen-III synthase
VspSTUT16_00580	COG0181	hydroxymethylbilane synthase activity
VspSTUT16_00590	COG3072	Adenylate cyclase
VspSTUT16_00600	COG1965	Belongs to the frataxin family
VspSTUT16_00610	COG0019	diaminopimelate decarboxylase activity
VspSTUT16_00620	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
VspSTUT16_00640	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
VspSTUT16_00650	COG1011	Hydrolase
VspSTUT16_00660	COG2199	diguanylate cyclase activity
VspSTUT16_00660	COG2200	EAL domain
VspSTUT16_00660	COG3287	FIST C domain
VspSTUT16_00670	COG3148	PFAM DTW domain containing protein
VspSTUT16_00700	COG0561	phosphatase activity
VspSTUT16_00710	COG2267	carboxylic ester hydrolase activity
VspSTUT16_00720	COG1280	lysine exporter protein (LysE YggA)
VspSTUT16_00730	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VspSTUT16_00740	COG0640	Transcriptional regulator
VspSTUT16_00750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VspSTUT16_00830	COG2095	MarC family integral membrane protein
VspSTUT16_00850	COG0742	ribosomal rna small subunit methyltransferase
VspSTUT16_00860	COG0552	protein localization to endoplasmic reticulum
VspSTUT16_00870	COG2884	Cell division ATP-binding protein ftsE
VspSTUT16_00880	COG2177	Part of the ABC transporter FtsEX involved in
VspSTUT16_00900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VspSTUT16_00910	COG0705	Rhomboid family
VspSTUT16_00920	COG1580	Controls the rotational direction of flagella during chemotaxis
VspSTUT16_00930	COG3161	chorismate lyase activity
VspSTUT16_00940	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
VspSTUT16_00950	COG2937	Belongs to the GPAT DAPAT family
VspSTUT16_00960	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VspSTUT16_00980	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
VspSTUT16_00990	COG0534	Mate efflux family protein
VspSTUT16_01000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VspSTUT16_01070	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VspSTUT16_01130	COG2003	Belongs to the UPF0758 family
VspSTUT16_01220	COG4206	TonB-dependent receptor
VspSTUT16_01260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VspSTUT16_01270	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VspSTUT16_01280	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
VspSTUT16_01280	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
VspSTUT16_01300	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VspSTUT16_01310	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VspSTUT16_01320	COG0250	Participates in transcription elongation, termination and antitermination
VspSTUT16_01350	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
VspSTUT16_01360	COG0222	ribosome binding
VspSTUT16_01370	COG0085	RNA polymerase activity
VspSTUT16_01380	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
VspSTUT16_01390	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
VspSTUT16_01400	COG2816	NAD+ diphosphatase activity
VspSTUT16_01410	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
VspSTUT16_01420	COG1573	uracil-dna glycosylase
VspSTUT16_01440	COG3068	Protein conserved in bacteria
VspSTUT16_01450	COG1253	flavin adenine dinucleotide binding
VspSTUT16_01480	COG0151	Belongs to the GarS family
VspSTUT16_01490	COG0138	bifunctional purine biosynthesis protein purh
VspSTUT16_01500	COG0789	Transcriptional regulator
VspSTUT16_01510	COG3710	Transcriptional regulator
VspSTUT16_01530	COG0531	amino acid
VspSTUT16_01540	COG1982	Orn Lys Arg decarboxylase major
VspSTUT16_01560	COG0488	(ABC) transporter
VspSTUT16_01580	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VspSTUT16_01590	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VspSTUT16_01600	COG2264	protein methyltransferase activity
VspSTUT16_01610	COG0439	Biotin carboxylase
VspSTUT16_01620	COG0511	ligase activity, forming carbon-carbon bonds
VspSTUT16_01630	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VspSTUT16_01640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VspSTUT16_01670	COG2814	Major facilitator Superfamily
VspSTUT16_01730	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VspSTUT16_01750	COG3263	regulation of cellular component size
VspSTUT16_01770	COG4232	protein-disulfide reductase activity
VspSTUT16_01780	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VspSTUT16_01790	COG1027	Aspartate ammonia-lyase
VspSTUT16_01810	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
VspSTUT16_01830	COG2205	protein histidine kinase activity
VspSTUT16_01840	COG0745	RESPONSE REGULATOR receiver
VspSTUT16_01850	COG3678	ATP-independent chaperone mediated protein folding
VspSTUT16_01860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
VspSTUT16_01870	COG0205	6-phosphofructokinase activity
VspSTUT16_01880	COG0534	Mate efflux family protein
VspSTUT16_01900	COG0459	protein refolding
VspSTUT16_01970	COG1285	pathogenesis
VspSTUT16_01980	COG1509	lysine 2,3-aminomutase activity
VspSTUT16_02020	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
VspSTUT16_02030	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VspSTUT16_02040	COG1053	succinate dehydrogenase
VspSTUT16_02050	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
VspSTUT16_02090	COG4942	peptidase
VspSTUT16_02100	COG1045	serine acetyltransferase
VspSTUT16_02110	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
VspSTUT16_02120	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
VspSTUT16_02130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VspSTUT16_02140	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
VspSTUT16_02160	COG0471	metal ion transport
VspSTUT16_02160	COG3273	potassium ion transport
VspSTUT16_02170	COG0688	phosphatidylethanolamine metabolic process
VspSTUT16_02180	COG1162	GTPase activity
VspSTUT16_02190	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
VspSTUT16_02200	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VspSTUT16_02210	COG0802	atpase or kinase
VspSTUT16_02230	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
VspSTUT16_02240	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
VspSTUT16_02260	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VspSTUT16_02270	COG0330	HflC and HflK could
VspSTUT16_02280	COG0330	HflC and HflK could
VspSTUT16_02290	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VspSTUT16_02300	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
VspSTUT16_02310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VspSTUT16_02310	COG1017	nitric oxide dioxygenase activity
VspSTUT16_02320	COG1959	2 iron, 2 sulfur cluster binding
VspSTUT16_02330	COG0557	exoribonuclease II activity
VspSTUT16_02340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VspSTUT16_02350	COG0546	phosphoglycolate phosphatase activity
VspSTUT16_02360	COG0180	Tryptophanyl-tRNA synthetase
VspSTUT16_02390	COG0512	Glutamine amidotransferase of anthranilate synthase
VspSTUT16_02400	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VspSTUT16_02440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VspSTUT16_02450	COG3954	Phosphoribulokinase
VspSTUT16_02460	COG3089	Belongs to the UPF0270 family
VspSTUT16_02470	COG0429	hydrolase of the alpha beta-hydrolase fold
VspSTUT16_02490	COG0488	(ABC) transporter
VspSTUT16_02500	COG2249	NAD(P)H dehydrogenase (quinone) activity
VspSTUT16_02530	COG1047	Peptidyl-prolyl cis-trans
VspSTUT16_02540	COG1446	asparaginase
VspSTUT16_02570	COG0545	Peptidyl-prolyl cis-trans isomerase
VspSTUT16_02580	COG2964	Protein conserved in bacteria
VspSTUT16_02590	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
VspSTUT16_02600	COG2923	Belongs to the DsrF TusC family
VspSTUT16_02610	COG2168	tRNA wobble position uridine thiolation
VspSTUT16_02640	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VspSTUT16_02650	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VspSTUT16_02670	COG0281	malic enzyme
VspSTUT16_02680	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
VspSTUT16_02690	COG0626	cystathionine gamma-synthase activity
VspSTUT16_02700	COG0527	aspartate kinase activity
VspSTUT16_02700	COG0460	homoserine dehydrogenase
VspSTUT16_02710	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VspSTUT16_02730	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VspSTUT16_02750	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
VspSTUT16_02770	COG0137	argininosuccinate synthase activity
VspSTUT16_02780	COG0165	Argininosuccinate lyase
VspSTUT16_02780	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VspSTUT16_02790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VspSTUT16_02800	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VspSTUT16_02800	COG0678	peroxiredoxin activity
VspSTUT16_02820	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
VspSTUT16_02880	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VspSTUT16_02890	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
VspSTUT16_02910	COG0338	D12 class N6 adenine-specific DNA methyltransferase
VspSTUT16_02920	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VspSTUT16_02930	COG0360	Binds together with S18 to 16S ribosomal RNA
VspSTUT16_02940	COG2965	DNA replication, synthesis of RNA primer
VspSTUT16_02990	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VspSTUT16_03000	COG0432	Pfam Uncharacterised protein family UPF0047
VspSTUT16_03010	COG0166	Belongs to the GPI family
VspSTUT16_03030	COG0735	belongs to the Fur family
VspSTUT16_03040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VspSTUT16_03080	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VspSTUT16_03090	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VspSTUT16_03100	COG0175	sulfate reduction
VspSTUT16_03120	COG1410	methionine synthase
VspSTUT16_03120	COG0646	methionine synthase
VspSTUT16_03130	COG0527	aspartate kinase activity
VspSTUT16_03140	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VspSTUT16_03160	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VspSTUT16_03190	COG0629	single-stranded DNA binding
VspSTUT16_03200	COG2199	diguanylate cyclase activity
VspSTUT16_03200	COG2200	EAL domain
VspSTUT16_03240	COG1450	Type ii and iii secretion system protein
VspSTUT16_03250	COG3409	Peptidoglycan-binding domain 1 protein
VspSTUT16_03250	COG3267	Type II secretory pathway component ExeA
VspSTUT16_03270	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VspSTUT16_03280	COG1459	type II secretion system
VspSTUT16_03300	COG2165	general secretion pathway protein
VspSTUT16_03370	COG1077	Cell shape determining protein MreB Mrl
VspSTUT16_03380	COG1792	Involved in formation and maintenance of cell shape
VspSTUT16_03390	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
VspSTUT16_03400	COG0424	maF-like protein
VspSTUT16_03420	COG3164	Protein of unknown function
VspSTUT16_03430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VspSTUT16_03440	COG0312	modulator of DNA gyrase
VspSTUT16_03450	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
VspSTUT16_03460	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VspSTUT16_03480	COG0564	pseudouridine synthase activity
VspSTUT16_03490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VspSTUT16_03500	COG3028	Belongs to the UPF0307 family
VspSTUT16_03510	COG0312	modulator of DNA gyrase
VspSTUT16_03520	COG2239	Acts as a magnesium transporter
VspSTUT16_03530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VspSTUT16_03540	COG1660	Displays ATPase and GTPase activities
VspSTUT16_03550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VspSTUT16_03560	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VspSTUT16_03580	COG1137	ATPase activity
VspSTUT16_03590	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VspSTUT16_03610	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
VspSTUT16_03610	COG0517	IMP dehydrogenase activity
VspSTUT16_03630	COG1127	ABC transporter
VspSTUT16_03640	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VspSTUT16_03650	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VspSTUT16_03660	COG2854	intermembrane phospholipid transfer
VspSTUT16_03680	COG5007	Belongs to the BolA IbaG family
VspSTUT16_03700	COG0204	Acyl-transferase
VspSTUT16_03710	COG0251	oxidation-reduction process
VspSTUT16_03720	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
VspSTUT16_03730	COG0540	Belongs to the ATCase OTCase family
VspSTUT16_03780	COG0456	acetyltransferase
VspSTUT16_03800	COG0525	valine-tRNA ligase activity
VspSTUT16_03810	COG2927	DNA polymerase III (CHI subunit)
VspSTUT16_03830	COG0795	lipopolysaccharide-transporting ATPase activity
VspSTUT16_03840	COG0795	lipopolysaccharide-transporting ATPase activity
VspSTUT16_03870	COG1028	Short-chain dehydrogenase reductase Sdr
VspSTUT16_03880	COG0726	polysaccharide deacetylase
VspSTUT16_03900	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VspSTUT16_03910	COG1447	Phosphotransferase system cellobiose-specific component IIA
VspSTUT16_03920	COG1486	melibiose metabolic process
VspSTUT16_03930	COG3394	polysaccharide catabolic process
VspSTUT16_03950	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VspSTUT16_03960	COG1012	belongs to the aldehyde dehydrogenase family
VspSTUT16_03990	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
VspSTUT16_04010	COG0220	tRNA (guanine-N7-)-methyltransferase activity
VspSTUT16_04030	COG2066	Belongs to the glutaminase family
VspSTUT16_04040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VspSTUT16_04050	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
VspSTUT16_04070	COG1872	DUF167
VspSTUT16_04080	COG0762	integral membrane protein
VspSTUT16_04090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
VspSTUT16_04100	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
VspSTUT16_04130	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VspSTUT16_04140	COG1678	Uncharacterized ACR, COG1678
VspSTUT16_04150	COG0189	ligase activity
VspSTUT16_04160	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VspSTUT16_04170	COG2356	endonuclease I
VspSTUT16_04210	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VspSTUT16_04220	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VspSTUT16_04230	COG0583	DNA-binding transcription factor activity
VspSTUT16_04240	COG4771	TonB-dependent receptor
VspSTUT16_04250	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VspSTUT16_04260	COG0126	phosphoglycerate kinase activity
VspSTUT16_04270	COG0191	fructose-bisphosphate aldolase activity
VspSTUT16_04280	COG0668	transmembrane transport
VspSTUT16_04310	COG0583	DNA-binding transcription factor activity
VspSTUT16_04330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VspSTUT16_04340	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
VspSTUT16_04350	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
VspSTUT16_04360	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
VspSTUT16_04370	COG3079	Belongs to the UPF0149 family
VspSTUT16_04380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VspSTUT16_04390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VspSTUT16_04420	COG0354	folic acid binding
VspSTUT16_04430	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
VspSTUT16_04440	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VspSTUT16_04450	COG1595	DNA-templated transcription, initiation
VspSTUT16_04480	COG3086	response to oxidative stress
VspSTUT16_04490	COG0481	GTPase activity
VspSTUT16_04500	COG0681	Belongs to the peptidase S26 family
VspSTUT16_04520	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VspSTUT16_04530	COG1381	Involved in DNA repair and RecF pathway recombination
VspSTUT16_04540	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
VspSTUT16_04550	COG0736	holo-[acyl-carrier-protein] synthase activity
VspSTUT16_04570	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VspSTUT16_04580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VspSTUT16_04590	COG3956	TIGRFAM MazG family protein
VspSTUT16_04600	COG0504	CTP synthase activity
VspSTUT16_04610	COG0148	phosphopyruvate hydratase activity
VspSTUT16_04620	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
VspSTUT16_04630	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VspSTUT16_04640	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
VspSTUT16_04660	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
VspSTUT16_04670	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
VspSTUT16_04690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VspSTUT16_04700	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
VspSTUT16_04780	COG1546	Belongs to the CinA family
VspSTUT16_04790	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VspSTUT16_04800	COG2137	regulation of response to DNA damage stimulus
VspSTUT16_04810	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
VspSTUT16_04820	COG0527	aspartate kinase activity
VspSTUT16_04850	COG3630	sodium ion export across plasma membrane
VspSTUT16_04860	COG5016	pyruvate
VspSTUT16_04860	COG0511	ligase activity, forming carbon-carbon bonds
VspSTUT16_04870	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VspSTUT16_04890	COG1238	metal cluster binding
VspSTUT16_04900	COG0612	Peptidase, M16
VspSTUT16_04930	COG1854	S-ribosylhomocysteine lyase activity
VspSTUT16_04940	COG4536	flavin adenine dinucleotide binding
VspSTUT16_04950	COG4137	Cytochrome C assembly protein
VspSTUT16_04960	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VspSTUT16_04970	COG0228	four-way junction DNA binding
VspSTUT16_04980	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
VspSTUT16_05010	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
VspSTUT16_05020	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
VspSTUT16_05030	COG0237	dephospho-CoA kinase activity
VspSTUT16_05050	COG1459	type II secretion system
VspSTUT16_05060	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VspSTUT16_05070	COG4969	Belongs to the N-Me-Phe pilin family
VspSTUT16_05100	COG2186	Transcriptional regulator
VspSTUT16_05110	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VspSTUT16_05120	COG0508	dehydrogenase complex catalyzes the overall conversion of
VspSTUT16_05130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VspSTUT16_05160	COG0288	reversible hydration of carbon dioxide
VspSTUT16_05170	COG0659	secondary active sulfate transmembrane transporter activity
VspSTUT16_05180	COG1131	(ABC) transporter
VspSTUT16_05190	COG0842	Transport permease protein
VspSTUT16_05200	COG1560	Kdo2-lipid A biosynthetic process
VspSTUT16_05210	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
VspSTUT16_05220	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
VspSTUT16_05230	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VspSTUT16_05250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VspSTUT16_05270	COG1489	DNA binding
VspSTUT16_05280	COG1643	Atp-dependent helicase
VspSTUT16_05290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VspSTUT16_05300	COG1752	Esterase of the alpha-beta hydrolase superfamily
VspSTUT16_05310	COG1049	propionate catabolic process, 2-methylcitrate cycle
VspSTUT16_05320	COG3112	Uncharacterised protein family (UPF0231)
VspSTUT16_05330	COG0347	Belongs to the P(II) protein family
VspSTUT16_05340	COG0004	ammonium transporteR
VspSTUT16_05350	COG1840	ABC-type Fe3 transport system, periplasmic component
VspSTUT16_05370	COG3842	ATPase activity
VspSTUT16_05380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VspSTUT16_05410	COG2971	BadF BadG BcrA BcrD
VspSTUT16_05430	COG4608	Belongs to the ABC transporter superfamily
VspSTUT16_05440	COG0444	Belongs to the ABC transporter superfamily
VspSTUT16_05450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VspSTUT16_05470	COG0747	negative chemotaxis
VspSTUT16_05480	COG0784	Response regulator, receiver
VspSTUT16_05480	COG2205	protein histidine kinase activity
VspSTUT16_05490	COG2813	Specifically methylates the guanine in position
VspSTUT16_05500	COG0628	permease
VspSTUT16_05510	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
VspSTUT16_05540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VspSTUT16_05550	COG0739	heme binding
VspSTUT16_05560	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VspSTUT16_05580	COG2027	D-alanyl-D-alanine carboxypeptidase
VspSTUT16_05590	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VspSTUT16_05600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VspSTUT16_05610	COG1534	Rna-binding protein
VspSTUT16_05620	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
VspSTUT16_05630	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VspSTUT16_05640	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
VspSTUT16_05650	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VspSTUT16_05660	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VspSTUT16_05670	COG0779	Required for maturation of 30S ribosomal subunits
VspSTUT16_05680	COG0195	Participates in both transcription termination and antitermination
VspSTUT16_05690	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
VspSTUT16_05700	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
VspSTUT16_05710	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
VspSTUT16_05720	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VspSTUT16_05730	COG1185	polyribonucleotide nucleotidyltransferase activity
VspSTUT16_05820	COG3344	reverse transcriptase
VspSTUT16_05840	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VspSTUT16_05870	COG3550	peptidyl-serine autophosphorylation
VspSTUT16_05930	COG0653	protein targeting
VspSTUT16_06040	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
VspSTUT16_06060	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VspSTUT16_06070	COG0534	Mate efflux family protein
VspSTUT16_06080	COG0826	peptidase U32
VspSTUT16_06090	COG0826	peptidase U32
VspSTUT16_06120	COG3154	lipid carrier protein
VspSTUT16_06130	COG3153	acetyltransferase
VspSTUT16_06170	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
VspSTUT16_06190	COG0084	hydrolase, TatD family'
VspSTUT16_06200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VspSTUT16_06220	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
VspSTUT16_06230	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
VspSTUT16_06240	COG0813	purine-nucleoside phosphorylase activity
VspSTUT16_06260	COG0560	Phosphoserine phosphatase
VspSTUT16_06280	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VspSTUT16_06290	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VspSTUT16_06300	COG0583	DNA-binding transcription factor activity
VspSTUT16_06320	COG1022	Amp-dependent synthetase and ligase
VspSTUT16_06330	COG2169	Transcriptional regulator
VspSTUT16_06380	COG4964	Belongs to the GSP D family
VspSTUT16_06500	COG0583	DNA-binding transcription factor activity
VspSTUT16_06510	COG0531	amino acid
VspSTUT16_06520	COG2731	YhcH YjgK YiaL family protein
VspSTUT16_06530	COG3250	beta-galactosidase activity
VspSTUT16_06540	COG1609	Transcriptional regulator
VspSTUT16_06550	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VspSTUT16_06570	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
VspSTUT16_06580	COG2017	converts alpha-aldose to the beta-anomer
VspSTUT16_06610	COG2176	DNA-directed DNA polymerase activity
VspSTUT16_06620	COG1609	Transcriptional regulator
VspSTUT16_06630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VspSTUT16_06670	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VspSTUT16_06680	COG1349	DNA-binding transcription factor activity
VspSTUT16_06690	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
VspSTUT16_06700	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VspSTUT16_06720	COG2271	Major facilitator Superfamily
VspSTUT16_06730	COG0584	glycerophosphoryl diester phosphodiesterase
VspSTUT16_06740	COG2171	N-acyltransferase activity
VspSTUT16_06750	COG3141	response to X-ray
VspSTUT16_06790	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VspSTUT16_06810	COG1074	ATP-dependent DNA helicase activity
VspSTUT16_06820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VspSTUT16_06860	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VspSTUT16_06860	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VspSTUT16_06880	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
VspSTUT16_06890	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VspSTUT16_06900	COG2166	iron-sulfur cluster assembly
VspSTUT16_06910	COG3706	GGDEF domain
VspSTUT16_06920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VspSTUT16_06930	COG0693	protein deglycase activity
VspSTUT16_06940	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VspSTUT16_06980	COG1595	DNA-templated transcription, initiation
VspSTUT16_07020	COG3056	Lipoprotein
VspSTUT16_07030	COG2813	Specifically methylates the guanine in position
VspSTUT16_07040	COG0271	Belongs to the BolA IbaG family
VspSTUT16_07060	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VspSTUT16_07070	COG1805	sodium ion transport
VspSTUT16_07080	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VspSTUT16_07090	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VspSTUT16_07100	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VspSTUT16_07110	COG2871	sodium ion transport
VspSTUT16_07120	COG1477	protein flavinylation
VspSTUT16_07150	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
VspSTUT16_07160	COG0514	ATP-dependent DNA helicase (RecQ)
VspSTUT16_07210	COG0733	neurotransmitter:sodium symporter activity
VspSTUT16_07250	COG0442	prolyl-tRNA aminoacylation
VspSTUT16_07260	COG1720	tRNA m6t6A37 methyltransferase activity
VspSTUT16_07270	COG0254	rRNA binding
VspSTUT16_07280	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VspSTUT16_07320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VspSTUT16_07330	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VspSTUT16_07400	COG0564	pseudouridine synthase activity
VspSTUT16_07420	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
VspSTUT16_07430	COG0024	Methionine aminopeptidase
VspSTUT16_07440	COG0052	Belongs to the universal ribosomal protein uS2 family
VspSTUT16_07450	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
VspSTUT16_07460	COG0528	UMP kinase activity
VspSTUT16_07470	COG0233	cytoplasmic translational termination
VspSTUT16_07480	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
VspSTUT16_07490	COG0575	Belongs to the CDS family
VspSTUT16_07500	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
VspSTUT16_07510	COG0750	zinc metalloprotease
VspSTUT16_07530	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
VspSTUT16_07540	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VspSTUT16_07560	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VspSTUT16_07570	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VspSTUT16_07590	COG0587	DNA-directed DNA polymerase activity
VspSTUT16_07600	COG0825	malonyl-CoA metabolic process
VspSTUT16_07630	COG0347	Belongs to the P(II) protein family
VspSTUT16_07640	COG3021	interspecies interaction between organisms
VspSTUT16_07660	COG0741	lytic transglycosylase activity
VspSTUT16_07660	COG1388	LysM domain
VspSTUT16_07670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VspSTUT16_07690	COG0328	RNA-DNA hybrid ribonuclease activity
VspSTUT16_07760	COG1960	acyl-CoA dehydrogenase activity
VspSTUT16_07770	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VspSTUT16_07780	COG0121	glutamine amidotransferase
VspSTUT16_07790	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VspSTUT16_07800	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
VspSTUT16_07810	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VspSTUT16_07820	COG2233	PERMEase
VspSTUT16_07870	COG1393	Belongs to the ArsC family
VspSTUT16_07880	COG4783	chaperone-mediated protein folding
VspSTUT16_07910	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VspSTUT16_07930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VspSTUT16_07940	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
VspSTUT16_07970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VspSTUT16_07980	COG1393	Belongs to the ArsC family
VspSTUT16_08030	COG2837	iron assimilation
VspSTUT16_08040	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VspSTUT16_08050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VspSTUT16_08060	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VspSTUT16_08070	COG1334	flagellar protein FlaG
VspSTUT16_08080	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VspSTUT16_08100	COG1516	flagellar protein fliS
VspSTUT16_08140	COG1677	Flagellar hook-basal body complex protein FliE
VspSTUT16_08160	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VspSTUT16_08260	COG1987	bacterial-type flagellum assembly
VspSTUT16_08270	COG1684	flagellar biosynthetic protein fliR
VspSTUT16_08340	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
VspSTUT16_08350	COG2198	Histidine kinase
VspSTUT16_08350	COG0784	Response regulator, receiver
VspSTUT16_08350	COG0643	Histidine kinase
VspSTUT16_08360	COG2201	protein-glutamate methylesterase activity
VspSTUT16_08370	COG1192	Involved in chromosome partitioning
VspSTUT16_08390	COG0835	chemotaxis
VspSTUT16_08410	COG4133	protoheme IX ABC transporter activity
VspSTUT16_08420	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VspSTUT16_08430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VspSTUT16_08440	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VspSTUT16_08450	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
VspSTUT16_08460	COG1138	Cytochrome C-type biogenesis protein
VspSTUT16_08470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VspSTUT16_08490	COG3088	subunit of a heme lyase
VspSTUT16_08490	COG4235	cytochrome complex assembly
VspSTUT16_08550	COG0183	Belongs to the thiolase family
VspSTUT16_08560	COG1250	3-hydroxyacyl-CoA dehydrogenase
VspSTUT16_08560	COG1024	Enoyl-CoA hydratase
VspSTUT16_08590	COG2062	phosphohistidine phosphatase, SixA
VspSTUT16_08600	COG2840	Smr protein MutS2
VspSTUT16_08610	COG2890	protein-(glutamine-N5) methyltransferase activity
VspSTUT16_08620	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
VspSTUT16_08630	COG2860	membrane
VspSTUT16_08640	COG3101	peptidyl-lysine hydroxylation
VspSTUT16_08660	COG0431	NADPH-dependent FMN reductase
VspSTUT16_08670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VspSTUT16_08670	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
VspSTUT16_08680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VspSTUT16_08690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VspSTUT16_08700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VspSTUT16_08720	COG0101	tRNA pseudouridine synthase activity
VspSTUT16_08730	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VspSTUT16_08740	COG0285	dihydrofolate synthase activity
VspSTUT16_08750	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
VspSTUT16_08760	COG1286	toxin biosynthetic process
VspSTUT16_08770	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VspSTUT16_08780	COG0583	DNA-binding transcription factor activity
VspSTUT16_08790	COG0745	RESPONSE REGULATOR receiver
VspSTUT16_08820	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
VspSTUT16_08850	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
VspSTUT16_08860	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VspSTUT16_08870	COG0814	amino acid
VspSTUT16_08880	COG0251	oxidation-reduction process
VspSTUT16_08890	COG3681	Belongs to the UPF0597 family
VspSTUT16_08920	COG2261	transglycosylase associated protein
VspSTUT16_08930	COG2983	Belongs to the UPF0260 family
VspSTUT16_08940	COG0668	transmembrane transport
VspSTUT16_08950	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
VspSTUT16_08960	COG0346	lactoylglutathione lyase activity
VspSTUT16_08980	COG1785	Belongs to the alkaline phosphatase family
VspSTUT16_09010	COG2226	methyltransferase
VspSTUT16_09040	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VspSTUT16_09050	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VspSTUT16_09070	COG3139	Protein of unknown function (DUF1315)
VspSTUT16_09080	COG0252	asparaginase activity
VspSTUT16_09090	COG0616	signal peptide processing
VspSTUT16_09100	COG0446	pyridine nucleotide-disulphide oxidoreductase
VspSTUT16_09100	COG1902	pentaerythritol trinitrate reductase activity
VspSTUT16_09120	COG0778	Nitroreductase
VspSTUT16_09130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VspSTUT16_09170	COG0123	including yeast histone deacetylase and acetoin utilization protein
VspSTUT16_09190	COG3082	Protein of unknown function (DUF1414)
VspSTUT16_09200	COG3081	Nucleoid-associated protein
VspSTUT16_09230	COG1757	Na H antiporter
VspSTUT16_09240	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VspSTUT16_09250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VspSTUT16_09260	COG2095	MarC family integral membrane protein
VspSTUT16_09270	COG1012	belongs to the aldehyde dehydrogenase family
VspSTUT16_09270	COG1454	alcohol dehydrogenase
VspSTUT16_09310	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VspSTUT16_09320	COG0653	protein targeting
VspSTUT16_09340	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
VspSTUT16_09490	COG4695	Portal protein
VspSTUT16_09690	COG5301	cellulose 1,4-beta-cellobiosidase activity
VspSTUT16_09780	COG2056	Na+-H+ antiporter family
VspSTUT16_09790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VspSTUT16_09800	COG2885	chlorophyll binding
VspSTUT16_09820	COG0346	lactoylglutathione lyase activity
VspSTUT16_09830	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VspSTUT16_09840	COG4660	Part of a membrane complex involved in electron transport
VspSTUT16_09850	COG4659	FMN binding
VspSTUT16_09860	COG4658	electron transport chain
VspSTUT16_09870	COG4656	Part of a membrane complex involved in electron transport
VspSTUT16_09880	COG2878	Part of a membrane complex involved in electron transport
VspSTUT16_09890	COG4657	Part of a membrane complex involved in electron transport
VspSTUT16_09910	COG0556	nucleotide-excision repair
VspSTUT16_09920	COG2204	response regulator
VspSTUT16_09930	COG2198	Histidine kinase
VspSTUT16_09940	COG0391	Required for morphogenesis under gluconeogenic growth conditions
VspSTUT16_09950	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VspSTUT16_09960	COG0521	Mo-molybdopterin cofactor biosynthetic process
VspSTUT16_09970	COG0315	cyclic pyranopterin monophosphate synthase activity
VspSTUT16_09980	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VspSTUT16_09990	COG0314	molybdopterin synthase activity
VspSTUT16_10010	COG0601	transmembrane transport
VspSTUT16_10020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VspSTUT16_10030	COG0444	Belongs to the ABC transporter superfamily
VspSTUT16_10050	COG0435	Glutathione S-transferase
VspSTUT16_10070	COG3174	membrane
VspSTUT16_10080	COG0280	phosphate acetyltransferase
VspSTUT16_10080	COG0857	belongs to the CobB CobQ family
VspSTUT16_10090	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VspSTUT16_10100	COG3092	negative regulation of chromosome organization
VspSTUT16_10120	COG4120	Belongs to the binding-protein-dependent transport system permease family
VspSTUT16_10130	COG1122	ATPase activity
VspSTUT16_10140	COG0366	Alpha amylase catalytic
VspSTUT16_10150	COG3706	GGDEF domain
VspSTUT16_10160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VspSTUT16_10170	COG0653	protein targeting
VspSTUT16_10180	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
VspSTUT16_10190	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VspSTUT16_10200	COG2186	Transcriptional regulator
VspSTUT16_10280	COG0572	uridine kinase
VspSTUT16_10300	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
VspSTUT16_10310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VspSTUT16_10320	COG0659	secondary active sulfate transmembrane transporter activity
VspSTUT16_10330	COG1530	ribonuclease E activity
VspSTUT16_10340	COG0564	pseudouridine synthase activity
VspSTUT16_10350	COG0424	maF-like protein
VspSTUT16_10360	COG1399	metal-binding, possibly nucleic acid-binding protein
VspSTUT16_10380	COG0416	fatty acid biosynthetic process
VspSTUT16_10390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VspSTUT16_10450	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VspSTUT16_10460	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
VspSTUT16_10470	COG0470	DNA polymerase III
VspSTUT16_10480	COG0084	hydrolase, TatD family'
VspSTUT16_10490	COG1263	PTS System
VspSTUT16_10490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VspSTUT16_10510	COG0733	neurotransmitter:sodium symporter activity
VspSTUT16_10530	COG4667	esterase of the alpha-beta hydrolase superfamily
VspSTUT16_10540	COG0469	pyruvate kinase activity
VspSTUT16_10550	COG1940	carbohydrate kinase activity
VspSTUT16_10560	COG0784	Response regulator, receiver
VspSTUT16_10560	COG0835	chemotaxis
VspSTUT16_10570	COG0587	DNA-directed DNA polymerase activity
VspSTUT16_10600	COG1028	Short-chain dehydrogenase reductase Sdr
VspSTUT16_10610	COG0616	signal peptide processing
VspSTUT16_10620	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
VspSTUT16_10630	COG0539	negative regulation of cytoplasmic translation
VspSTUT16_10650	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
VspSTUT16_10660	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VspSTUT16_10680	COG4166	transmembrane transport
VspSTUT16_10710	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VspSTUT16_10710	COG3008	intermembrane lipid transfer
VspSTUT16_10720	COG2995	paraquat-inducible protein a
VspSTUT16_10730	COG3258	Cytochrome c
VspSTUT16_10740	COG2863	cytochrome
VspSTUT16_10820	COG4232	protein-disulfide reductase activity
VspSTUT16_10830	COG3118	belongs to the thioredoxin family
VspSTUT16_10870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VspSTUT16_10890	COG1136	(ABC) transporter
VspSTUT16_10890	COG0577	efflux transmembrane transporter activity
VspSTUT16_10900	COG0577	efflux transmembrane transporter activity
VspSTUT16_10900	COG1136	(ABC) transporter
VspSTUT16_10910	COG0577	efflux transmembrane transporter activity
VspSTUT16_10910	COG1136	(ABC) transporter
VspSTUT16_11010	COG3850	Histidine kinase
VspSTUT16_11010	COG5002	protein histidine kinase activity
VspSTUT16_11020	COG0745	RESPONSE REGULATOR receiver
VspSTUT16_11030	COG0840	transmembrane signaling receptor activity
VspSTUT16_11040	COG0840	transmembrane signaling receptor activity
VspSTUT16_11050	COG1032	radical SAM domain protein
VspSTUT16_11060	COG5001	Diguanylate cyclase
VspSTUT16_11090	COG0583	DNA-binding transcription factor activity
VspSTUT16_11100	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
VspSTUT16_11120	COG2350	Protein conserved in bacteria
VspSTUT16_11150	COG2917	probably involved in intracellular septation
VspSTUT16_11190	COG1301	dicarboxylic acid transport
VspSTUT16_11200	COG0318	PFAM AMP-dependent synthetase and ligase
VspSTUT16_11210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VspSTUT16_11220	COG0159	tryptophan synthase activity
VspSTUT16_11240	COG0135	phosphoribosylanthranilate isomerase activity
VspSTUT16_11240	COG0134	indole-3-glycerol-phosphate synthase activity
VspSTUT16_11260	COG0512	Glutamine amidotransferase of anthranilate synthase
VspSTUT16_11270	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VspSTUT16_11280	COG0613	PHP domain protein
VspSTUT16_11290	COG0009	L-threonylcarbamoyladenylate synthase
VspSTUT16_11310	COG1187	pseudouridine synthase activity
VspSTUT16_11350	COG0417	DNA replication proofreading
VspSTUT16_11360	COG2197	response regulator
VspSTUT16_11370	COG0322	excinuclease ABC activity
VspSTUT16_11420	COG0019	diaminopimelate decarboxylase activity
VspSTUT16_11480	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VspSTUT16_11490	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VspSTUT16_11530	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
VspSTUT16_11550	COG0437	4 iron, 4 sulfur cluster binding
VspSTUT16_11560	COG3301	Polysulphide reductase, NrfD
VspSTUT16_11570	COG1138	Cytochrome C-type biogenesis protein
VspSTUT16_11590	COG4235	cytochrome complex assembly
VspSTUT16_11590	COG3088	subunit of a heme lyase
VspSTUT16_11610	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VspSTUT16_11660	COG2989	Protein conserved in bacteria
VspSTUT16_11670	COG3108	Peptidase M15
VspSTUT16_11680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VspSTUT16_11710	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VspSTUT16_11770	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VspSTUT16_11780	COG0840	transmembrane signaling receptor activity
VspSTUT16_11830	COG1448	Aminotransferase
VspSTUT16_11860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VspSTUT16_11880	COG0017	Asparaginyl-tRNA synthetase
VspSTUT16_11890	COG0840	transmembrane signaling receptor activity
VspSTUT16_11900	COG0720	synthase
VspSTUT16_11920	COG2200	EAL domain
VspSTUT16_11930	COG1760	l-serine dehydratase
VspSTUT16_11940	COG0814	amino acid
VspSTUT16_11950	COG0494	nUDIX hydrolase
VspSTUT16_11970	COG0784	Response regulator, receiver
VspSTUT16_11970	COG2205	protein histidine kinase activity
VspSTUT16_11980	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VspSTUT16_12010	COG3106	COG3106 Predicted ATPase
VspSTUT16_12020	COG3768	UPF0283 membrane protein
VspSTUT16_12040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VspSTUT16_12080	COG0456	acetyltransferase
VspSTUT16_12080	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
VspSTUT16_12220	COG0346	lactoylglutathione lyase activity
VspSTUT16_12270	COG0583	DNA-binding transcription factor activity
VspSTUT16_12280	COG4989	oxidoreductase activity
VspSTUT16_12310	COG3344	reverse transcriptase
VspSTUT16_12330	COG1196	nuclear chromosome segregation
VspSTUT16_12340	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VspSTUT16_12350	COG1085	galactose-1-phosphate uridylyltransferase
VspSTUT16_12370	COG2017	converts alpha-aldose to the beta-anomer
VspSTUT16_12380	COG1609	Transcriptional regulator
VspSTUT16_12390	COG1609	Transcriptional regulator
VspSTUT16_12400	COG3250	beta-galactosidase activity
VspSTUT16_12420	COG4580	involved in the transport of maltose and maltodextrins
VspSTUT16_12440	COG2211	Major facilitator Superfamily
VspSTUT16_12480	COG3344	reverse transcriptase
VspSTUT16_12510	COG1733	regulation of RNA biosynthetic process
VspSTUT16_12530	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
VspSTUT16_12760	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VspSTUT16_12790	COG2017	converts alpha-aldose to the beta-anomer
VspSTUT16_12860	COG2186	Transcriptional regulator
VspSTUT16_12870	COG2731	YhcH YjgK YiaL family protein
VspSTUT16_12890	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
VspSTUT16_12900	COG1063	alcohol dehydrogenase
VspSTUT16_12910	COG0246	Mannitol dehydrogenase
VspSTUT16_12930	COG0800	Aldolase
VspSTUT16_12940	COG4948	Mandelate Racemase Muconate Lactonizing
VspSTUT16_12970	COG0534	Mate efflux family protein
VspSTUT16_13000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VspSTUT16_13020	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VspSTUT16_13060	COG0148	phosphopyruvate hydratase activity
VspSTUT16_13090	COG2801	Transposase and inactivated derivatives
VspSTUT16_13130	COG0395	ABC-type sugar transport system, permease component
VspSTUT16_13140	COG1175	transmembrane transport
VspSTUT16_13170	COG2186	Transcriptional regulator
VspSTUT16_13180	COG1012	belongs to the aldehyde dehydrogenase family
VspSTUT16_13200	COG2814	Major facilitator Superfamily
VspSTUT16_13240	COG3250	beta-galactosidase activity
VspSTUT16_13260	COG4580	involved in the transport of maltose and maltodextrins
VspSTUT16_13300	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VspSTUT16_13320	COG1609	Transcriptional regulator
VspSTUT16_13340	COG1929	Belongs to the glycerate kinase type-1 family
VspSTUT16_13350	COG0383	alpha-mannosidase activity
VspSTUT16_13360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VspSTUT16_13360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VspSTUT16_13360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VspSTUT16_13370	COG2188	Transcriptional regulator
VspSTUT16_13790	COG2026	Addiction module toxin, RelE StbE family
VspSTUT16_13940	COG1051	belongs to the nudix hydrolase family
VspSTUT16_14550	COG5507	3-demethylubiquinone-9 3-methyltransferase
VspSTUT16_14560	COG1280	lysine exporter protein (LysE YggA)
VspSTUT16_14610	COG0583	DNA-binding transcription factor activity
VspSTUT16_14630	COG1566	PFAM secretion protein HlyD family protein
VspSTUT16_14640	COG3119	arylsulfatase activity
VspSTUT16_14670	COG0641	radical SAM
VspSTUT16_14700	COG1349	DNA-binding transcription factor activity
VspSTUT16_14710	COG0673	inositol 2-dehydrogenase activity
VspSTUT16_14720	COG4702	Belongs to the UPF0303 family
VspSTUT16_14770	COG0471	metal ion transport
VspSTUT16_14780	COG4191	Histidine kinase
VspSTUT16_14800	COG3300	MHYT domain
VspSTUT16_14800	COG5001	Diguanylate cyclase
VspSTUT16_14830	COG1328	CTP reductase activity
VspSTUT16_14840	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VspSTUT16_14860	COG0861	Integral membrane protein TerC family
VspSTUT16_14880	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VspSTUT16_14900	COG0814	amino acid
VspSTUT16_14930	COG1120	ATPase activity
VspSTUT16_14940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VspSTUT16_14960	COG4774	siderophore transport
VspSTUT16_14980	COG1132	(ABC) transporter
VspSTUT16_14990	COG1132	(ABC) transporter
VspSTUT16_15000	COG2165	general secretion pathway protein
VspSTUT16_15040	COG0443	Heat shock 70 kDa protein
VspSTUT16_15050	COG0443	Heat shock 70 kDa protein
VspSTUT16_15140	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
VspSTUT16_15150	COG1643	Atp-dependent helicase
VspSTUT16_15180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VspSTUT16_15200	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VspSTUT16_15210	COG1215	transferase activity, transferring glycosyl groups
VspSTUT16_15220	COG0438	transferase activity, transferring glycosyl groups
VspSTUT16_15280	COG0438	transferase activity, transferring glycosyl groups
VspSTUT16_15300	COG2204	response regulator
VspSTUT16_15360	COG1793	dna ligase
VspSTUT16_15380	COG0534	Mate efflux family protein
VspSTUT16_15390	COG0307	riboflavin synthase, alpha
VspSTUT16_15410	COG3001	Fructosamine kinase
VspSTUT16_15430	COG3706	GGDEF domain
VspSTUT16_15450	COG0791	NLP P60 protein
VspSTUT16_15510	COG3148	PFAM DTW domain containing protein
VspSTUT16_15520	COG1940	carbohydrate kinase activity
VspSTUT16_15540	COG0303	'Molybdopterin
VspSTUT16_15550	COG0746	molybdenum cofactor guanylyltransferase activity
VspSTUT16_15560	COG3842	ATPase activity
VspSTUT16_15590	COG2204	response regulator
VspSTUT16_15600	COG4191	Histidine kinase
VspSTUT16_15610	COG0488	(ABC) transporter
VspSTUT16_15620	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VspSTUT16_15660	COG3381	protein complex oligomerization
VspSTUT16_15680	COG0243	molybdopterin cofactor binding
VspSTUT16_15680	COG3383	formate dehydrogenase (NAD+) activity
VspSTUT16_15690	COG0437	4 iron, 4 sulfur cluster binding
VspSTUT16_15900	COG4282	regulation of fungal-type cell wall biogenesis
VspSTUT16_15940	COG0004	ammonium transporteR
VspSTUT16_15960	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VspSTUT16_15970	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VspSTUT16_15990	COG1177	transmembrane transport
VspSTUT16_16010	COG3842	ATPase activity
VspSTUT16_16060	COG0589	response to stress
VspSTUT16_16070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VspSTUT16_16100	COG2217	Heavy metal translocating P-type atpase
VspSTUT16_16120	COG2010	Cytochrome c
VspSTUT16_16150	COG3278	Belongs to the heme-copper respiratory oxidase family
VspSTUT16_16180	COG0784	Response regulator, receiver
VspSTUT16_16180	COG2205	protein histidine kinase activity
VspSTUT16_16210	COG3120	sequence-specific DNA binding
VspSTUT16_16220	COG1067	ATP-dependent peptidase activity
VspSTUT16_16230	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VspSTUT16_16260	COG0488	(ABC) transporter
VspSTUT16_16280	COG0116	Belongs to the methyltransferase superfamily
VspSTUT16_16280	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VspSTUT16_16300	COG0167	dihydroorotate dehydrogenase activity
VspSTUT16_16310	COG2902	Dehydrogenase
VspSTUT16_16330	COG0308	aminopeptidase N
VspSTUT16_16360	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
VspSTUT16_16370	COG1956	GAF domain-containing protein
VspSTUT16_16380	COG1132	(ABC) transporter
VspSTUT16_16390	COG2995	paraquat-inducible protein a
VspSTUT16_16400	COG3008	intermembrane lipid transfer
VspSTUT16_16450	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VspSTUT16_16460	COG1666	GTP binding
VspSTUT16_16480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VspSTUT16_16490	COG4597	amino acid ABC transporter
VspSTUT16_16500	COG0765	amino acid transport
VspSTUT16_16510	COG1126	abc transporter atp-binding protein
VspSTUT16_16520	COG0670	Belongs to the BI1 family
VspSTUT16_16540	COG2920	part of a sulfur-relay system
VspSTUT16_16550	COG1254	Belongs to the acylphosphatase family
VspSTUT16_16620	COG3344	reverse transcriptase
VspSTUT16_16680	COG3706	GGDEF domain
VspSTUT16_16690	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
VspSTUT16_16700	COG0602	queuosine metabolic process
VspSTUT16_16710	COG0561	phosphatase activity
VspSTUT16_16760	COG2828	Protein conserved in bacteria
VspSTUT16_16780	COG0372	Belongs to the citrate synthase family
VspSTUT16_16790	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
VspSTUT16_16860	COG0730	response to heat
VspSTUT16_16870	COG2358	TRAP transporter, solute receptor (TAXI family
VspSTUT16_16910	COG0457	Tetratricopeptide repeat
VspSTUT16_17050	COG4790	Type iii secretion
VspSTUT16_17060	COG4794	Type iii secretion
VspSTUT16_17070	COG4791	protein targeting
VspSTUT16_17080	COG4792	protein secretion
VspSTUT16_17140	COG1028	Short-chain dehydrogenase reductase Sdr
VspSTUT16_17200	COG3177	Filamentation induced by cAMP protein fic
VspSTUT16_17240	COG4669	(LipO)protein
VspSTUT16_17380	COG1012	belongs to the aldehyde dehydrogenase family
VspSTUT16_17390	COG3284	Transcriptional regulator
VspSTUT16_17430	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
VspSTUT16_17440	COG0363	glucosamine-6-phosphate deaminase activity
VspSTUT16_17450	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VspSTUT16_17480	COG4565	transcriptional regulatory protein
VspSTUT16_17490	COG3290	protein histidine kinase activity
VspSTUT16_17520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VspSTUT16_17550	COG1858	cytochrome C peroxidase
VspSTUT16_17560	COG1858	cytochrome C peroxidase
VspSTUT16_17570	COG0527	aspartate kinase activity
VspSTUT16_17580	COG0662	Cupin 2, conserved barrel domain protein
VspSTUT16_17590	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VspSTUT16_17600	COG0456	acetyltransferase
VspSTUT16_17610	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VspSTUT16_17650	COG4176	ABC-type proline glycine betaine transport system permease component
VspSTUT16_17660	COG2113	Glycine betaine
VspSTUT16_17700	COG1028	Short-chain dehydrogenase reductase Sdr
VspSTUT16_17720	COG0745	RESPONSE REGULATOR receiver
VspSTUT16_17730	COG0642	Histidine kinase
VspSTUT16_17740	COG1368	sulfuric ester hydrolase activity
VspSTUT16_17800	COG1115	amino acid carrier protein
VspSTUT16_17820	COG1280	lysine exporter protein (LysE YggA)
VspSTUT16_17830	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VspSTUT16_17840	COG1560	Kdo2-lipid A biosynthetic process
VspSTUT16_17850	COG0531	amino acid
VspSTUT16_17880	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
VspSTUT16_17890	COG3063	Type IV pilus biogenesis stability protein PilW
VspSTUT16_17950	COG0110	maltose O-acetyltransferase activity
VspSTUT16_17980	COG2315	Protein conserved in bacteria
VspSTUT16_17990	COG1846	Transcriptional regulator
VspSTUT16_18010	COG2200	EAL domain
VspSTUT16_18060	COG0625	glutathione transferase activity
VspSTUT16_18080	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
VspSTUT16_18100	COG2195	Cleaves the N-terminal amino acid of tripeptides
VspSTUT16_18120	COG0601	transmembrane transport
VspSTUT16_18130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VspSTUT16_18170	COG3291	Pkd domain containing protein
VspSTUT16_18190	COG1177	transmembrane transport
VspSTUT16_18200	COG1176	ABC-type spermidine putrescine transport system, permease component I
VspSTUT16_18210	COG3842	ATPase activity
VspSTUT16_18220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VspSTUT16_18230	COG2423	ornithine cyclodeaminase activity
VspSTUT16_18260	COG3938	Belongs to the proline racemase family
VspSTUT16_18330	COG1451	nucleotide metabolic process
VspSTUT16_18350	COG0583	DNA-binding transcription factor activity
VspSTUT16_18390	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
VspSTUT16_18400	COG4139	cobalamin transport
VspSTUT16_18410	COG2988	succinylglutamate desuccinylase activity
VspSTUT16_18450	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
VspSTUT16_18460	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
VspSTUT16_18470	COG0702	epimerase
VspSTUT16_18480	COG1823	symporter activity
VspSTUT16_18490	COG2925	Exonuclease
VspSTUT16_18500	COG1380	Effector of murein hydrolase LrgA
VspSTUT16_18510	COG1346	cytolysis
VspSTUT16_18520	COG0295	cytidine deaminase activity
VspSTUT16_18530	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
VspSTUT16_18540	COG0500	methyltransferase
VspSTUT16_18560	COG0776	regulation of translation
VspSTUT16_18580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VspSTUT16_18580	COG0072	phenylalanine-tRNA ligase activity
VspSTUT16_18590	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
VspSTUT16_18650	COG0393	Putative heavy-metal-binding
VspSTUT16_18670	COG0291	Belongs to the bacterial ribosomal protein bL35 family
VspSTUT16_18690	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
VspSTUT16_18720	COG2188	Transcriptional regulator
VspSTUT16_18730	COG1228	amidohydrolase
VspSTUT16_18740	COG0010	Belongs to the arginase family
VspSTUT16_18750	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
VspSTUT16_18760	COG2986	histidine ammonia-lyase
VspSTUT16_18790	COG0247	lactate metabolic process
VspSTUT16_18790	COG0277	FAD linked oxidase domain protein
VspSTUT16_18860	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
VspSTUT16_18890	COG1643	Atp-dependent helicase
VspSTUT16_18900	COG0281	malic enzyme
VspSTUT16_18910	COG2949	membrane
VspSTUT16_18920	COG0471	metal ion transport
VspSTUT16_18970	COG0492	ferredoxin-NADP+ reductase activity
VspSTUT16_18980	COG4988	ABC transporter
VspSTUT16_18990	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
VspSTUT16_19010	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VspSTUT16_19030	COG4191	Histidine kinase
VspSTUT16_19030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VspSTUT16_19060	COG3070	regulator of competence-specific genes
VspSTUT16_19080	COG2431	L-lysine efflux transmembrane transporter activity
VspSTUT16_19100	COG0076	glutamate decarboxylase activity
VspSTUT16_19110	COG1737	Transcriptional regulator
VspSTUT16_19130	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VspSTUT16_19140	COG2985	domain, Protein
VspSTUT16_19140	COG3273	potassium ion transport
VspSTUT16_19150	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VspSTUT16_19160	COG1960	acyl-CoA dehydrogenase activity
VspSTUT16_19180	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VspSTUT16_19220	COG0534	Mate efflux family protein
VspSTUT16_19230	COG0702	epimerase
VspSTUT16_19240	COG3005	denitrification pathway
VspSTUT16_19300	COG2814	Major facilitator Superfamily
VspSTUT16_19310	COG1187	pseudouridine synthase activity
VspSTUT16_19320	COG1061	Type III restriction enzyme res subunit
VspSTUT16_19360	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
VspSTUT16_19430	COG4134	Bacterial extracellular solute-binding protein
VspSTUT16_19440	COG4135	transport system, permease component
VspSTUT16_19450	COG4136	ATPase activity
VspSTUT16_19460	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VspSTUT16_19480	COG3604	Transcriptional regulator
VspSTUT16_19490	COG1151	hydroxylamine reductase activity
VspSTUT16_19500	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VspSTUT16_19520	COG0564	pseudouridine synthase activity
VspSTUT16_19530	COG0733	neurotransmitter:sodium symporter activity
VspSTUT16_19550	COG0626	cystathionine gamma-synthase activity
VspSTUT16_19560	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
VspSTUT16_19570	COG5380	lipid catabolic process
VspSTUT16_19580	COG2818	Glycosylase
VspSTUT16_19620	COG1983	PspC domain protein
VspSTUT16_19640	COG1842	Phage shock protein A
VspSTUT16_19650	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
VspSTUT16_19680	COG4171	peptide transport system, permease
VspSTUT16_19700	COG4172	Belongs to the ABC transporter superfamily
VspSTUT16_19720	COG1227	inorganic diphosphatase activity
VspSTUT16_19750	COG0243	molybdopterin cofactor binding
VspSTUT16_19760	COG3005	denitrification pathway
VspSTUT16_19770	COG4459	periplasmic nitrate reductase
VspSTUT16_19780	COG0390	transport system, permease component
VspSTUT16_19800	COG2116	formate transmembrane transporter activity
VspSTUT16_19850	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VspSTUT16_19860	COG1435	thymidine kinase activity
VspSTUT16_19870	COG0215	cysteine-tRNA ligase activity
VspSTUT16_19880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VspSTUT16_19890	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VspSTUT16_19910	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VspSTUT16_19920	COG3012	SEC-C Motif Domain Protein
VspSTUT16_19930	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
VspSTUT16_19930	COG0140	phosphoribosyl-ATP diphosphatase activity
VspSTUT16_19950	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
VspSTUT16_19960	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VspSTUT16_19970	COG0131	Imidazoleglycerol-phosphate dehydratase
VspSTUT16_19970	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VspSTUT16_19980	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VspSTUT16_19990	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
VspSTUT16_20000	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
VspSTUT16_20020	COG1757	Na H antiporter
VspSTUT16_20040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VspSTUT16_20060	COG0482	sulfurtransferase activity
VspSTUT16_20070	COG2915	High frequency lysogenization protein hflD homolog
VspSTUT16_20080	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VspSTUT16_20100	COG2268	Band 7 protein
VspSTUT16_20120	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VspSTUT16_20150	COG0300	oxidoreductase activity
VspSTUT16_20190	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
VspSTUT16_20200	COG1073	alpha beta
VspSTUT16_20200	COG2226	methyltransferase
VspSTUT16_20240	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
VspSTUT16_20250	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VspSTUT16_20260	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
VspSTUT16_20270	COG1674	ftsk spoiiie
VspSTUT16_20290	COG0686	Belongs to the AlaDH PNT family
VspSTUT16_20310	COG0583	DNA-binding transcription factor activity
VspSTUT16_20340	COG0840	transmembrane signaling receptor activity
VspSTUT16_20360	COG3568	Endonuclease Exonuclease Phosphatase
VspSTUT16_20410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VspSTUT16_20420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VspSTUT16_20430	COG0840	transmembrane signaling receptor activity
VspSTUT16_20450	COG0784	Response regulator, receiver
VspSTUT16_20450	COG5002	protein histidine kinase activity
VspSTUT16_20470	COG0754	glutathionylspermidine amidase activity
VspSTUT16_20490	COG3766	membrane
VspSTUT16_20510	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
VspSTUT16_20520	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
VspSTUT16_20530	COG2885	chlorophyll binding
VspSTUT16_20540	COG0823	Involved in the tonB-independent uptake of proteins
VspSTUT16_20570	COG0811	peptide transport
VspSTUT16_20580	COG0824	Thioesterase
VspSTUT16_20600	COG1294	oxidase, subunit
VspSTUT16_20610	COG1271	oxidase subunit
VspSTUT16_20620	COG2255	four-way junction helicase activity
VspSTUT16_20630	COG0632	four-way junction helicase activity
VspSTUT16_20640	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
VspSTUT16_20650	COG0217	transcriptional regulatory protein
VspSTUT16_20670	COG1801	Protein of unknown function DUF72
VspSTUT16_20690	COG0500	methyltransferase
VspSTUT16_20700	COG4067	protein conserved in archaea
VspSTUT16_20700	COG0189	ligase activity
VspSTUT16_20740	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
VspSTUT16_20750	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
VspSTUT16_20760	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
VspSTUT16_20770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VspSTUT16_20780	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VspSTUT16_20790	COG0745	RESPONSE REGULATOR receiver
VspSTUT16_20800	COG3381	protein complex oligomerization
VspSTUT16_20810	COG1609	Transcriptional regulator
VspSTUT16_20820	COG3070	regulator of competence-specific genes
VspSTUT16_20860	COG0297	glycogen (starch) synthase activity
VspSTUT16_20870	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VspSTUT16_20880	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VspSTUT16_20920	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
VspSTUT16_20930	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
VspSTUT16_20940	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VspSTUT16_20950	COG0542	response to heat
VspSTUT16_20960	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
VspSTUT16_20970	COG1278	Cold shock
VspSTUT16_20990	COG1187	pseudouridine synthase activity
VspSTUT16_21000	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VspSTUT16_21020	COG1199	ATP-dependent helicase activity
VspSTUT16_21030	COG0730	response to heat
VspSTUT16_21040	COG3923	Primosomal replication protein n
VspSTUT16_21060	COG0708	Exodeoxyribonuclease III
VspSTUT16_21140	COG1882	Formate acetyltransferase
VspSTUT16_21160	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VspSTUT16_21180	COG3013	Belongs to the UPF0304 family
VspSTUT16_21190	COG2766	serine protein kinase
VspSTUT16_21200	COG2718	Belongs to the UPF0229 family
VspSTUT16_21210	COG2719	SpoVR family
VspSTUT16_21250	COG1132	(ABC) transporter
VspSTUT16_21260	COG2333	competence protein COMEC
VspSTUT16_21260	COG0658	competence protein
VspSTUT16_21280	COG4591	ABC-type transport system involved in lipoprotein release permease component
VspSTUT16_21290	COG1136	(ABC) transporter
VspSTUT16_21300	COG4591	ABC-type transport system involved in lipoprotein release permease component
VspSTUT16_21320	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
VspSTUT16_21350	COG1252	NADH dehydrogenase
VspSTUT16_21360	COG3150	esterase
VspSTUT16_21410	COG0537	adenosine 5'-monophosphoramidase activity
VspSTUT16_21460	COG0516	GMP reductase activity
VspSTUT16_21460	COG0517	IMP dehydrogenase activity
VspSTUT16_21470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VspSTUT16_21480	COG3293	Transposase
VspSTUT16_21490	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
VspSTUT16_21510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VspSTUT16_21530	COG1902	pentaerythritol trinitrate reductase activity
VspSTUT16_21540	COG1902	pentaerythritol trinitrate reductase activity
VspSTUT16_21580	COG0583	DNA-binding transcription factor activity
VspSTUT16_21590	COG2814	Major facilitator Superfamily
VspSTUT16_21660	COG2814	Major facilitator Superfamily
VspSTUT16_21670	COG0596	Alpha beta hydrolase
VspSTUT16_21700	COG0633	Ferredoxin
VspSTUT16_21700	COG3217	Mosc domain protein beta barrel domain protein
VspSTUT16_21720	COG1028	Short-chain dehydrogenase reductase Sdr
VspSTUT16_21730	COG0861	Integral membrane protein TerC family
VspSTUT16_21750	COG3118	belongs to the thioredoxin family
VspSTUT16_21890	COG3126	Type III secretion system lipoprotein chaperone (YscW)
VspSTUT16_21900	COG1946	Acyl-CoA thioesterase
VspSTUT16_21920	COG1522	sequence-specific DNA binding
VspSTUT16_21970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VspSTUT16_21980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VspSTUT16_22010	COG0477	Major facilitator Superfamily
VspSTUT16_22020	COG2855	membrane
VspSTUT16_22060	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
VspSTUT16_22070	COG0596	Alpha beta hydrolase
VspSTUT16_22080	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
VspSTUT16_22090	COG1169	isochorismate synthase
VspSTUT16_22110	COG0436	Aminotransferase
VspSTUT16_22120	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
VspSTUT16_22130	COG0232	Belongs to the dGTPase family. Type 2 subfamily
VspSTUT16_22160	COG1555	photosystem II stabilization
VspSTUT16_22170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VspSTUT16_22180	COG0776	regulation of translation
VspSTUT16_22190	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VspSTUT16_22200	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
VspSTUT16_22220	COG0544	peptidyl-prolyl cis-trans isomerase activity
VspSTUT16_22260	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VspSTUT16_22270	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VspSTUT16_22280	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VspSTUT16_22290	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
VspSTUT16_22320	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VspSTUT16_22330	COG0569	domain protein
VspSTUT16_22340	COG0513	Belongs to the DEAD box helicase family
VspSTUT16_22350	COG1253	flavin adenine dinucleotide binding
VspSTUT16_22420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VspSTUT16_22430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VspSTUT16_22460	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VspSTUT16_22470	COG1216	Glycosyl transferase, family 2
VspSTUT16_22480	COG2986	histidine ammonia-lyase
VspSTUT16_22530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VspSTUT16_22550	COG1028	Short-chain dehydrogenase reductase Sdr
VspSTUT16_22580	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
VspSTUT16_22590	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VspSTUT16_22610	COG2951	lytic endotransglycosylase activity
VspSTUT16_22620	COG3100	YcgL domain-containing protein
VspSTUT16_22630	COG0850	regulation of cytokinetic process
VspSTUT16_22640	COG2894	cell division
VspSTUT16_22650	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
VspSTUT16_22660	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
VspSTUT16_22670	COG0318	PFAM AMP-dependent synthetase and ligase
VspSTUT16_22680	COG2267	carboxylic ester hydrolase activity
VspSTUT16_22690	COG3065	identical protein binding
VspSTUT16_22710	COG1214	PFAM Peptidase M22, glycoprotease
VspSTUT16_22720	COG1199	ATP-dependent helicase activity
VspSTUT16_22740	COG0788	formyltetrahydrofolate deformylase activity
VspSTUT16_22750	COG3102	Protein conserved in bacteria
VspSTUT16_22760	COG0018	arginyl-trna synthetase
VspSTUT16_22800	COG1918	ferrous iron import across plasma membrane
VspSTUT16_22810	COG4977	sequence-specific DNA binding
VspSTUT16_22820	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
VspSTUT16_22830	COG1121	(ABC) transporter
VspSTUT16_22840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VspSTUT16_22870	COG0508	dehydrogenase complex catalyzes the overall conversion of
VspSTUT16_22880	COG0567	Dehydrogenase, E1 component
VspSTUT16_22890	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VspSTUT16_22900	COG1053	succinate dehydrogenase
VspSTUT16_22910	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
VspSTUT16_22940	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VspSTUT16_22960	COG0033	Phosphoglucomutase
VspSTUT16_22970	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
VspSTUT16_22980	COG0596	Alpha beta hydrolase
VspSTUT16_23000	COG0716	FMN binding
VspSTUT16_23020	COG0735	belongs to the Fur family
VspSTUT16_23030	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VspSTUT16_23040	COG1263	PTS System
VspSTUT16_23040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VspSTUT16_23040	COG2190	(PTS) system
VspSTUT16_23050	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VspSTUT16_23060	COG1846	Transcriptional regulator
VspSTUT16_23060	COG1940	carbohydrate kinase activity
VspSTUT16_23070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VspSTUT16_23070	COG4651	solute:proton antiporter activity
VspSTUT16_23080	COG0367	asparagine synthase
VspSTUT16_23090	COG0250	Participates in transcription elongation, termination and antitermination
VspSTUT16_23100	COG3104	oligopeptide transport
VspSTUT16_23110	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VspSTUT16_23130	COG0326	Molecular chaperone. Has ATPase activity
VspSTUT16_23140	COG3710	Transcriptional regulator
VspSTUT16_23180	COG0622	Phosphoesterase
VspSTUT16_23240	COG1090	epimerase
VspSTUT16_23250	COG0300	oxidoreductase activity
VspSTUT16_23260	COG3118	belongs to the thioredoxin family
VspSTUT16_23270	COG0330	HflC and HflK could
VspSTUT16_23330	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
VspSTUT16_23340	COG3115	cell septum assembly
VspSTUT16_23350	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
VspSTUT16_23360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VspSTUT16_23370	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VspSTUT16_23380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
VspSTUT16_23390	COG2190	(PTS) system
VspSTUT16_23400	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VspSTUT16_23410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VspSTUT16_23420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VspSTUT16_23430	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VspSTUT16_23450	COG1705	Flagellar rod assembly protein muramidase FlgJ
VspSTUT16_23450	COG3951	Flagellar rod assembly protein muramidase FlgJ
VspSTUT16_23460	COG1706	bacterial-type flagellum-dependent cell motility
VspSTUT16_23470	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VspSTUT16_23490	COG4787	bacterial-type flagellum-dependent cell motility
VspSTUT16_23500	COG1749	Flagellar hook protein flgE
VspSTUT16_23520	COG1558	bacterial-type flagellum-dependent cell motility
VspSTUT16_23530	COG1815	bacterial-type flagellum-dependent cell motility
VspSTUT16_23540	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VspSTUT16_23550	COG0784	Response regulator, receiver
VspSTUT16_23550	COG0835	chemotaxis
VspSTUT16_23650	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VspSTUT16_23680	COG2217	Heavy metal translocating P-type atpase
VspSTUT16_23680	COG2608	mercury ion transmembrane transporter activity
VspSTUT16_23750	COG2840	Smr protein MutS2
VspSTUT16_23760	COG1187	pseudouridine synthase activity
VspSTUT16_23780	COG0737	Belongs to the 5'-nucleotidase family
VspSTUT16_23790	COG2877	3-deoxy-8-phosphooctulonate synthase activity
VspSTUT16_23800	COG2912	Transglutaminase-like superfamily
VspSTUT16_23810	COG3094	Invasion gene expression up-regulator, SirB
VspSTUT16_23820	COG2890	protein-(glutamine-N5) methyltransferase activity
VspSTUT16_23830	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
VspSTUT16_23840	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
VspSTUT16_23850	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
VspSTUT16_23860	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
VspSTUT16_23870	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VspSTUT16_23880	COG0193	aminoacyl-tRNA hydrolase activity
VspSTUT16_23890	COG0012	GTP binding
VspSTUT16_23900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VspSTUT16_23910	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VspSTUT16_23920	COG1702	phosphate starvation-inducible protein PhoH
VspSTUT16_23930	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
VspSTUT16_23940	COG4535	Mg2 and Co2 transporter CorC
VspSTUT16_23950	COG0815	Transfers the fatty acyl group on membrane lipoproteins
VspSTUT16_23960	COG2888	peptidyl-tyrosine sulfation
VspSTUT16_23970	COG0495	leucyl-tRNA aminoacylation
VspSTUT16_23980	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
VspSTUT16_23990	COG1466	dna polymerase III delta subunit
VspSTUT16_24000	COG0799	negative regulation of ribosome biogenesis
VspSTUT16_24010	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
VspSTUT16_24020	COG0768	penicillin binding
VspSTUT16_24030	COG0772	Belongs to the SEDS family
VspSTUT16_24040	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VspSTUT16_24050	COG1686	Belongs to the peptidase S11 family
VspSTUT16_24070	COG0321	lipoyl(octanoyl) transferase activity
VspSTUT16_24080	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
VspSTUT16_24090	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VspSTUT16_24100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
VspSTUT16_24130	COG0366	Alpha amylase catalytic
VspSTUT16_24140	COG1263	PTS System
VspSTUT16_24140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VspSTUT16_24160	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VspSTUT16_24170	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
VspSTUT16_24180	COG2011	ABC-type metal ion transport system permease component
VspSTUT16_24190	COG1464	Belongs to the NlpA lipoprotein family
VspSTUT16_24200	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
VspSTUT16_24220	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VspSTUT16_24220	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VspSTUT16_24250	COG1611	Belongs to the LOG family
VspSTUT16_24260	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VspSTUT16_24280	COG2363	Small membrane protein
VspSTUT16_24300	COG0583	DNA-binding transcription factor activity
VspSTUT16_24310	COG0301	tRNA thio-modification
VspSTUT16_24310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VspSTUT16_24330	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VspSTUT16_24340	COG1722	exodeoxyribonuclease VII activity
VspSTUT16_24350	COG0142	geranyltranstransferase activity
VspSTUT16_24360	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
VspSTUT16_24370	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VspSTUT16_24380	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
VspSTUT16_24400	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
VspSTUT16_24430	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VspSTUT16_24430	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VspSTUT16_24440	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VspSTUT16_24450	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
VspSTUT16_24460	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
VspSTUT16_24480	COG1073	alpha beta
VspSTUT16_24490	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
VspSTUT16_24500	COG2252	PERMEase
VspSTUT16_24510	COG2195	Cleaves the N-terminal amino acid of tripeptides
VspSTUT16_24540	COG1629	transport
VspSTUT16_24570	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VspSTUT16_24570	COG0047	phosphoribosylformylglycinamidine synthase activity
VspSTUT16_24580	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
VspSTUT16_24610	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VspSTUT16_24650	COG4969	Belongs to the N-Me-Phe pilin family
VspSTUT16_24670	COG0484	heat shock protein binding
VspSTUT16_24690	COG1301	dicarboxylic acid transport
VspSTUT16_24700	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VspSTUT16_24710	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
VspSTUT16_24730	COG0497	DNA recombination
VspSTUT16_24750	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VspSTUT16_24760	COG2914	Belongs to the UPF0125 (RnfH) family
VspSTUT16_24770	COG2867	negative regulation of translational initiation
VspSTUT16_24780	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
VspSTUT16_24820	COG0583	DNA-binding transcription factor activity
VspSTUT16_24830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VspSTUT16_24830	COG3153	acetyltransferase
VspSTUT16_24870	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
VspSTUT16_24880	COG2873	o-acetylhomoserine
VspSTUT16_24920	COG1115	amino acid carrier protein
VspSTUT16_24930	COG1584	GPR1 FUN34 yaaH family protein
VspSTUT16_24950	COG1757	Na H antiporter
VspSTUT16_24970	COG0519	Catalyzes the synthesis of GMP from XMP
VspSTUT16_24970	COG0518	GMP synthase (glutamine-hydrolyzing) activity
VspSTUT16_24980	COG0516	GMP reductase activity
VspSTUT16_24980	COG0517	IMP dehydrogenase activity
VspSTUT16_25020	COG1160	GTP binding
VspSTUT16_25030	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VspSTUT16_25040	COG2976	Protein conserved in bacteria
VspSTUT16_25050	COG0124	histidyl-tRNA synthetase
VspSTUT16_25060	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
VspSTUT16_25090	COG0105	UTP biosynthetic process
VspSTUT16_25110	COG2975	iron-sulfur cluster assembly
VspSTUT16_25120	COG0633	Ferredoxin
VspSTUT16_25130	COG0443	Heat shock 70 kDa protein
VspSTUT16_25160	COG0822	iron-sulfur transferase activity
VspSTUT16_25170	COG1104	cysteine desulfurase activity
VspSTUT16_25190	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
VspSTUT16_25200	COG0483	inositol monophosphate 1-phosphatase activity
VspSTUT16_25210	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VspSTUT16_25220	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VspSTUT16_25230	COG1862	Preprotein translocase
VspSTUT16_25250	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
VspSTUT16_25270	COG0517	IMP dehydrogenase activity
VspSTUT16_25290	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
VspSTUT16_25300	COG0583	DNA-binding transcription factor activity
VspSTUT16_25310	COG0450	alkyl hydroperoxide reductase
VspSTUT16_25320	COG3142	Participates in the control of copper homeostasis
VspSTUT16_25340	COG0704	Plays a role in the regulation of phosphate uptake
VspSTUT16_25350	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VspSTUT16_25360	COG0581	inorganic phosphate transmembrane transporter activity
VspSTUT16_25370	COG0573	inorganic phosphate transmembrane transporter activity
VspSTUT16_25380	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
VspSTUT16_25390	COG0248	Ppx GppA phosphatase
VspSTUT16_25410	COG5002	protein histidine kinase activity
VspSTUT16_25420	COG0745	RESPONSE REGULATOR receiver
VspSTUT16_25430	COG2974	May be involved in recombination
VspSTUT16_25440	COG0826	peptidase U32
VspSTUT16_25450	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VspSTUT16_25490	COG0542	response to heat
VspSTUT16_25510	COG0564	pseudouridine synthase activity
VspSTUT16_25520	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VspSTUT16_25530	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
VspSTUT16_25540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VspSTUT16_25550	COG0077	Prephenate dehydratase
VspSTUT16_25550	COG1605	Chorismate mutase
VspSTUT16_25560	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
VspSTUT16_25570	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
VspSTUT16_25590	COG0488	(ABC) transporter
VspSTUT16_25610	COG0739	heme binding
VspSTUT16_25610	COG0741	lytic transglycosylase activity
VspSTUT16_25610	COG1196	nuclear chromosome segregation
VspSTUT16_25620	COG0287	Prephenate dehydrogenase
VspSTUT16_25620	COG1605	Chorismate mutase
VspSTUT16_25630	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VspSTUT16_25640	COG1472	Belongs to the glycosyl hydrolase 3 family
VspSTUT16_25650	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VspSTUT16_25690	COG1966	Carbon starvation protein
VspSTUT16_25710	COG3275	phosphorelay sensor kinase activity
VspSTUT16_25720	COG3279	Response regulator of the LytR AlgR family
VspSTUT16_25740	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VspSTUT16_25750	COG1047	Peptidyl-prolyl cis-trans
VspSTUT16_25760	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
VspSTUT16_25780	COG0196	riboflavin kinase activity
VspSTUT16_25790	COG0728	peptidoglycan biosynthetic process
VspSTUT16_25800	COG0268	Binds directly to 16S ribosomal RNA
VspSTUT16_25810	COG0640	Transcriptional regulator
VspSTUT16_25820	COG0583	DNA-binding transcription factor activity
VspSTUT16_25830	COG1283	sodium-dependent phosphate transmembrane transporter activity
VspSTUT16_25850	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
VspSTUT16_25860	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
VspSTUT16_25870	COG0730	response to heat
VspSTUT16_25920	COG0667	Aldo Keto reductase
VspSTUT16_25940	COG2204	response regulator
VspSTUT16_25950	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
VspSTUT16_25960	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
VspSTUT16_25970	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VspSTUT16_25980	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VspSTUT16_25990	COG4974	Belongs to the 'phage' integrase family
VspSTUT16_26000	COG0716	FMN binding
VspSTUT16_26020	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
VspSTUT16_26030	COG0513	Belongs to the DEAD box helicase family
VspSTUT16_26040	COG3022	response to hydroperoxide
VspSTUT16_26050	COG1115	amino acid carrier protein
VspSTUT16_26080	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
VspSTUT16_26090	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
VspSTUT16_26100	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
VspSTUT16_26120	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
VspSTUT16_26130	COG0083	homoserine kinase activity
VspSTUT16_26160	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VspSTUT16_26180	COG0745	RESPONSE REGULATOR receiver
VspSTUT16_26200	COG2198	Histidine kinase
VspSTUT16_26200	COG0784	Response regulator, receiver
VspSTUT16_26200	COG5002	protein histidine kinase activity
VspSTUT16_26210	COG5001	Diguanylate cyclase
VspSTUT16_26210	COG4251	negative regulation of phosphorylation
VspSTUT16_26210	COG2203	Gaf domain
VspSTUT16_26210	COG3706	GGDEF domain
VspSTUT16_26220	COG1242	4 iron, 4 sulfur cluster binding
VspSTUT16_26230	COG0069	glutamate synthase activity
VspSTUT16_26230	COG0070	glutamate synthase
VspSTUT16_26230	COG0067	glutamate synthase
VspSTUT16_26250	COG0067	glutamate synthase
VspSTUT16_26250	COG0069	glutamate synthase activity
VspSTUT16_26250	COG0070	glutamate synthase
VspSTUT16_26260	COG0493	'glutamate synthase
VspSTUT16_26280	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VspSTUT16_26310	COG2860	membrane
VspSTUT16_26320	COG0583	DNA-binding transcription factor activity
VspSTUT16_26350	COG0730	response to heat
VspSTUT16_26390	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VspSTUT16_26400	COG0505	Belongs to the CarA family
VspSTUT16_26430	COG0494	nUDIX hydrolase
VspSTUT16_26440	COG0653	protein targeting
VspSTUT16_26460	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
VspSTUT16_26470	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VspSTUT16_26480	COG0849	cell division
VspSTUT16_26490	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VspSTUT16_26500	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VspSTUT16_26520	COG0772	Belongs to the SEDS family
VspSTUT16_26530	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
VspSTUT16_26540	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
VspSTUT16_26550	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VspSTUT16_26560	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VspSTUT16_26570	COG0768	penicillin binding
VspSTUT16_26580	COG3116	cell division
VspSTUT16_26610	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VspSTUT16_26640	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VspSTUT16_26650	COG2823	Periplasmic or secreted lipoprotein
VspSTUT16_26660	COG2969	positive regulation of protein catabolic process
VspSTUT16_26670	COG0625	glutathione transferase activity
VspSTUT16_26680	COG2857	Cytochrome c1
VspSTUT16_26690	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VspSTUT16_26700	COG0723	plastoquinol--plastocyanin reductase activity
VspSTUT16_26710	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
VspSTUT16_26720	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
VspSTUT16_26730	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VspSTUT16_26740	COG3105	Protein conserved in bacteria
VspSTUT16_26760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VspSTUT16_26770	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
VspSTUT16_26790	COG3150	esterase
VspSTUT16_26810	COG3151	Protein conserved in bacteria
VspSTUT16_26820	COG0494	nUDIX hydrolase
VspSTUT16_26830	COG1538	Outer membrane efflux protein
VspSTUT16_26840	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
VspSTUT16_26840	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
VspSTUT16_26850	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VspSTUT16_26880	COG3025	triphosphatase activity
VspSTUT16_26890	COG1392	Phosphate transport regulator
VspSTUT16_26900	COG0306	phosphate transporter
VspSTUT16_26910	COG4991	sh3 domain protein
VspSTUT16_26920	COG0405	Gamma-glutamyltransferase
VspSTUT16_26940	COG3267	Type II secretory pathway component ExeA
VspSTUT16_26940	COG3409	Peptidoglycan-binding domain 1 protein
VspSTUT16_26960	COG1968	undecaprenyl-diphosphatase activity
VspSTUT16_26970	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VspSTUT16_26980	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
VspSTUT16_26990	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
VspSTUT16_27000	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
VspSTUT16_27010	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
VspSTUT16_27020	COG0828	Belongs to the bacterial ribosomal protein bS21 family
VspSTUT16_27030	COG1610	YqeY-like protein
VspSTUT16_27040	COG0358	DNA primase activity
VspSTUT16_27130	COG2213	PTS system mannitol-specific
VspSTUT16_27130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VspSTUT16_27140	COG0246	Mannitol dehydrogenase
VspSTUT16_27150	COG3722	fumarate hydratase activity
VspSTUT16_27180	COG1461	Dihydroxyacetone kinase
VspSTUT16_27190	COG2376	Dihydroxyacetone kinase
VspSTUT16_27210	COG5002	protein histidine kinase activity
VspSTUT16_27240	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
VspSTUT16_27250	COG1349	DNA-binding transcription factor activity
VspSTUT16_27260	COG0469	pyruvate kinase activity
VspSTUT16_27300	COG0028	Belongs to the TPP enzyme family
VspSTUT16_27310	COG1022	Amp-dependent synthetase and ligase
VspSTUT16_27320	COG0583	DNA-binding transcription factor activity
VspSTUT16_27370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
VspSTUT16_27380	COG0473	3-isopropylmalate dehydrogenase activity
VspSTUT16_27420	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VspSTUT16_27430	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
VspSTUT16_27440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VspSTUT16_27450	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
VspSTUT16_27460	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
VspSTUT16_27470	COG2967	ApaG domain
VspSTUT16_27480	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
VspSTUT16_27520	COG2966	Psort location CytoplasmicMembrane, score
VspSTUT16_27530	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VspSTUT16_27550	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VspSTUT16_27560	COG0142	geranyltranstransferase activity
VspSTUT16_27600	COG2358	TRAP transporter, solute receptor (TAXI family
VspSTUT16_27630	COG1902	pentaerythritol trinitrate reductase activity
VspSTUT16_27640	COG0583	DNA-binding transcription factor activity
VspSTUT16_27650	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
VspSTUT16_27660	COG1178	ABC-type Fe3 transport system permease component
VspSTUT16_27670	COG4143	(ABC) transporter
VspSTUT16_27680	COG0163	prenyltransferase activity
VspSTUT16_27690	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VspSTUT16_27700	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
VspSTUT16_27710	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
VspSTUT16_27730	COG2105	PFAM AIG2 family protein
VspSTUT16_27740	COG2911	Protein conserved in bacteria
VspSTUT16_27750	COG0729	surface antigen
VspSTUT16_27760	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VspSTUT16_27780	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VspSTUT16_27800	COG4181	ATPase activity
VspSTUT16_27840	COG0529	Catalyzes the synthesis of activated sulfate
VspSTUT16_27850	COG0471	metal ion transport
VspSTUT16_27850	COG3273	potassium ion transport
VspSTUT16_27860	COG2895	sulfate adenylyltransferase (ATP) activity
VspSTUT16_27870	COG0175	sulfate reduction
VspSTUT16_27880	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VspSTUT16_27880	COG1648	precorrin-2 dehydrogenase activity
VspSTUT16_27910	COG0513	Belongs to the DEAD box helicase family
VspSTUT16_27920	COG2153	protein acetylation
VspSTUT16_27940	COG0545	Peptidyl-prolyl cis-trans isomerase
VspSTUT16_27960	COG0203	ribosomal protein L17
VspSTUT16_27970	COG0202	RNA polymerase activity
VspSTUT16_27990	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VspSTUT16_28000	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VspSTUT16_28010	COG0201	protein transport
VspSTUT16_28020	COG0200	Binds to the 23S rRNA
VspSTUT16_28030	COG1841	ribosomal large subunit assembly
VspSTUT16_28060	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
VspSTUT16_28070	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
VspSTUT16_28080	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
VspSTUT16_28090	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VspSTUT16_28100	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
VspSTUT16_28120	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
VspSTUT16_28130	COG0255	Belongs to the universal ribosomal protein uL29 family
VspSTUT16_28150	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
VspSTUT16_28160	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
VspSTUT16_28170	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
VspSTUT16_28180	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VspSTUT16_28200	COG0088	Forms part of the polypeptide exit tunnel
VspSTUT16_28210	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
VspSTUT16_28230	COG0254	rRNA binding
VspSTUT16_28240	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VspSTUT16_28250	COG1609	Transcriptional regulator
VspSTUT16_28270	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
VspSTUT16_28280	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
VspSTUT16_28290	COG1575	Belongs to the MenA family. Type 1 subfamily
VspSTUT16_28300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VspSTUT16_28320	COG1494	fructose-1,6-bisphosphatase
VspSTUT16_28370	COG0149	triose-phosphate isomerase activity
VspSTUT16_28480	COG5039	Polysaccharide pyruvyl transferase
VspSTUT16_28510	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
VspSTUT16_28520	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
VspSTUT16_28530	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VspSTUT16_28540	COG1215	transferase activity, transferring glycosyl groups
VspSTUT16_28700	COG1450	Type ii and iii secretion system protein
VspSTUT16_28720	COG1459	type II secretion system
VspSTUT16_28730	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VspSTUT16_28790	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VspSTUT16_28810	COG1560	Kdo2-lipid A biosynthetic process
VspSTUT16_28830	COG0859	PFAM glycosyl transferase family 9
VspSTUT16_28840	COG1519	Transferase
VspSTUT16_28850	COG0471	metal ion transport
VspSTUT16_28850	COG3273	potassium ion transport
VspSTUT16_28860	COG0175	sulfate reduction
VspSTUT16_28870	COG0529	Catalyzes the synthesis of activated sulfate
VspSTUT16_28880	COG2895	sulfate adenylyltransferase (ATP) activity
VspSTUT16_28930	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
VspSTUT16_28950	COG3642	lipopolysaccharide core region biosynthetic process
VspSTUT16_28960	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VspSTUT16_28970	COG0859	PFAM glycosyl transferase family 9
VspSTUT16_28980	COG0463	Glycosyl transferase, family 2
VspSTUT16_28990	COG0438	transferase activity, transferring glycosyl groups
VspSTUT16_29060	COG2003	Belongs to the UPF0758 family
VspSTUT16_29080	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
VspSTUT16_29090	COG1309	transcriptional regulator
VspSTUT16_29100	COG1560	Kdo2-lipid A biosynthetic process
VspSTUT16_29110	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
VspSTUT16_29120	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
VspSTUT16_29130	COG1561	YicC-like family, N-terminal region
VspSTUT16_29210	COG3344	reverse transcriptase
VspSTUT16_29310	COG1757	Na H antiporter
VspSTUT16_29340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VspSTUT16_29360	COG4608	Belongs to the ABC transporter superfamily
VspSTUT16_29370	COG0444	Belongs to the ABC transporter superfamily
VspSTUT16_29380	COG0747	negative chemotaxis
VspSTUT16_29390	COG4239	(ABC) transporter, permease
VspSTUT16_29400	COG4174	ABC transporter (Permease)
VspSTUT16_29440	COG0811	peptide transport
VspSTUT16_29450	COG0848	biopolymer transport protein
VspSTUT16_29480	COG0194	GDP metabolic process
VspSTUT16_29490	COG1758	RNA polymerase activity
VspSTUT16_29500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VspSTUT16_29510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VspSTUT16_29520	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VspSTUT16_29530	COG2233	PERMEase
VspSTUT16_29570	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VspSTUT16_29590	COG2183	response to ionizing radiation
VspSTUT16_29610	COG0596	Alpha beta hydrolase
VspSTUT16_29620	COG0316	Belongs to the HesB IscA family
VspSTUT16_29620	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
VspSTUT16_29630	COG0494	nUDIX hydrolase
VspSTUT16_29640	COG1218	3'(2'),5'-bisphosphate nucleotidase
VspSTUT16_29660	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VspSTUT16_29670	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VspSTUT16_29680	COG3156	type II secretion system protein K
VspSTUT16_29690	COG4795	General secretion pathway protein
VspSTUT16_29700	COG2165	general secretion pathway protein
VspSTUT16_29710	COG2165	general secretion pathway protein
VspSTUT16_29720	COG2165	general secretion pathway protein
VspSTUT16_29730	COG1459	type II secretion system
VspSTUT16_29740	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VspSTUT16_29760	COG3031	protein transport across the cell outer membrane
VspSTUT16_29770	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VspSTUT16_29780	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
VspSTUT16_29790	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
VspSTUT16_29810	COG0456	acetyltransferase
VspSTUT16_29820	COG1490	D-aminoacyl-tRNA deacylase activity
VspSTUT16_29830	COG1295	ribonuclease BN
VspSTUT16_29860	COG1217	gtp-binding protein TYPA
VspSTUT16_29870	COG0174	glutamine synthetase
VspSTUT16_29890	COG3852	Histidine kinase
VspSTUT16_29900	COG2204	response regulator
VspSTUT16_29920	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VspSTUT16_29980	COG0218	Necessary for normal cell division and for the maintenance of normal septation
VspSTUT16_29990	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VspSTUT16_29990	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VspSTUT16_30000	COG0456	acetyltransferase
VspSTUT16_30020	COG0084	hydrolase, TatD family'
VspSTUT16_30030	COG0805	protein transport
VspSTUT16_30040	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VspSTUT16_30060	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
VspSTUT16_30070	COG3165	ubiquinone biosynthetic process from chorismate
VspSTUT16_30080	COG2226	methyltransferase
VspSTUT16_30090	COG1322	Protein conserved in bacteria
VspSTUT16_30120	COG0628	permease
VspSTUT16_30180	COG1597	lipid kinase activity
VspSTUT16_30230	COG2204	response regulator
VspSTUT16_30240	COG2081	HI0933 family
VspSTUT16_30260	COG1528	Iron-storage protein
VspSTUT16_30270	COG0589	response to stress
VspSTUT16_30280	COG0697	spore germination
VspSTUT16_30300	COG0742	ribosomal rna small subunit methyltransferase
VspSTUT16_30310	COG5002	protein histidine kinase activity
VspSTUT16_30310	COG5001	Diguanylate cyclase
VspSTUT16_30320	COG1522	sequence-specific DNA binding
VspSTUT16_30340	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VspSTUT16_30350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VspSTUT16_30400	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VspSTUT16_30410	COG0583	DNA-binding transcription factor activity
VspSTUT16_30420	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
VspSTUT16_30430	COG0800	Aldolase
VspSTUT16_30440	COG2610	gluconate transmembrane transporter activity
VspSTUT16_30450	COG3265	gluconokinase activity
VspSTUT16_30460	COG0129	dihydroxy-acid dehydratase activity
VspSTUT16_30490	COG0583	DNA-binding transcription factor activity
VspSTUT16_30500	COG1609	Transcriptional regulator
VspSTUT16_30570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VspSTUT16_30580	COG0601	transmembrane transport
VspSTUT16_30590	COG4166	transmembrane transport
VspSTUT16_30650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VspSTUT16_30660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VspSTUT16_30670	COG2960	long-chain fatty acid transporting porin activity
VspSTUT16_30680	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
VspSTUT16_30690	COG0583	DNA-binding transcription factor activity
VspSTUT16_30700	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
VspSTUT16_30720	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
VspSTUT16_30730	COG0408	coproporphyrinogen oxidase activity
VspSTUT16_30740	COG0009	L-threonylcarbamoyladenylate synthase
VspSTUT16_30750	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VspSTUT16_30760	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
VspSTUT16_30770	COG0551	DNA topoisomerase type I activity
VspSTUT16_30790	COG2922	Belongs to the Smg family
VspSTUT16_30800	COG0758	DNA mediated transformation
VspSTUT16_30820	COG0242	peptide deformylase activity
VspSTUT16_30830	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
VspSTUT16_30840	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VspSTUT16_30840	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VspSTUT16_30850	COG0569	domain protein
VspSTUT16_30860	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VspSTUT16_30880	COG1272	protein, Hemolysin III
VspSTUT16_30890	COG4326	sporulation control protein
VspSTUT16_30910	COG3084	Protein conserved in bacteria
VspSTUT16_30930	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VspSTUT16_30940	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VspSTUT16_30950	COG0204	Acyl-transferase
VspSTUT16_30980	COG0606	chelatase, subunit chli
VspSTUT16_31000	COG3978	acetolactate synthase activity
VspSTUT16_31010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VspSTUT16_31020	COG0129	dihydroxy-acid dehydratase activity
VspSTUT16_31040	COG0583	DNA-binding transcription factor activity
VspSTUT16_31050	COG2814	Major facilitator Superfamily
VspSTUT16_31070	COG0765	amino acid transport
VspSTUT16_31090	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VspSTUT16_31100	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
VspSTUT16_31110	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VspSTUT16_31120	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
VspSTUT16_31130	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
VspSTUT16_31140	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
VspSTUT16_31160	COG0356	it plays a direct role in the translocation of protons across the membrane
VspSTUT16_31170	COG3312	ion transport
VspSTUT16_31180	COG1475	DNA binding
VspSTUT16_31190	COG1192	Involved in chromosome partitioning
VspSTUT16_31200	COG0357	Ribosomal RNA small subunit methyltransferase G
VspSTUT16_31210	COG0445	tRNA wobble uridine modification
VspSTUT16_31220	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VspSTUT16_31240	COG0706	membrane insertase activity
VspSTUT16_31250	COG0594	ribonuclease P activity
VspSTUT16_31270	COG1126	abc transporter atp-binding protein
VspSTUT16_31340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VspSTUT16_31370	COG1328	CTP reductase activity
VspSTUT16_31380	COG0602	queuosine metabolic process
VspSTUT16_31390	COG0534	Mate efflux family protein
VspSTUT16_31400	COG2207	Transcriptional regulator
VspSTUT16_31420	COG4067	protein conserved in archaea
VspSTUT16_31420	COG0189	ligase activity
VspSTUT16_31440	COG3111	PFAM Bacterial OB fold (BOF) protein
VspSTUT16_31460	COG0725	ABC transporter, periplasmic molybdate-binding protein
VspSTUT16_31470	COG4149	molybdate abc transporter
VspSTUT16_31480	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
VspSTUT16_31500	COG3706	GGDEF domain
VspSTUT16_31500	COG2203	Gaf domain
VspSTUT16_31500	COG5001	Diguanylate cyclase
VspSTUT16_31500	COG4251	negative regulation of phosphorylation
VspSTUT16_31560	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
VspSTUT16_31570	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
VspSTUT16_31620	COG3140	Belongs to the UPF0181 family
VspSTUT16_31650	COG0589	response to stress
VspSTUT16_31670	COG0583	DNA-binding transcription factor activity
VspSTUT16_31710	COG0023	Translation Initiation Factor
VspSTUT16_31730	COG1181	Belongs to the D-alanine--D-alanine ligase family
VspSTUT16_31760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VspSTUT16_31760	COG1042	CoA-binding domain protein
VspSTUT16_31760	COG0045	succinate-CoA ligase (ADP-forming) activity
VspSTUT16_31770	COG0583	DNA-binding transcription factor activity
VspSTUT16_31790	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VspSTUT16_31800	COG5001	Diguanylate cyclase
VspSTUT16_31800	COG5002	protein histidine kinase activity
VspSTUT16_31800	COG3447	MASE1 domain protein
VspSTUT16_31810	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
VspSTUT16_31820	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
VspSTUT16_31830	COG1984	allophanate hydrolase subunit 2
VspSTUT16_31850	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
VspSTUT16_31860	COG4181	ATPase activity
VspSTUT16_31880	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VspSTUT16_31890	COG1716	ATPase activity
VspSTUT16_31890	COG5001	Diguanylate cyclase
VspSTUT16_31960	COG4533	DNA binding
VspSTUT16_31980	COG2050	protein possibly involved in aromatic compounds catabolism
VspSTUT16_32010	COG2067	long-chain fatty acid transport protein
VspSTUT16_32020	COG2267	carboxylic ester hydrolase activity
VspSTUT16_32070	COG0737	Belongs to the 5'-nucleotidase family
VspSTUT16_32080	COG3593	DNA synthesis involved in DNA repair
VspSTUT16_32100	COG0583	DNA-binding transcription factor activity
VspSTUT16_32110	COG2116	formate transmembrane transporter activity
VspSTUT16_32120	COG2353	YceI-like domain
VspSTUT16_32130	COG3038	cytochrome b561
VspSTUT16_32160	COG4943	cyclic-guanylate-specific phosphodiesterase activity
VspSTUT16_32170	COG0513	Belongs to the DEAD box helicase family
VspSTUT16_32210	COG0546	phosphoglycolate phosphatase activity
VspSTUT16_32240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VspSTUT16_32250	COG2759	Belongs to the formate--tetrahydrofolate ligase family
VspSTUT16_32260	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VspSTUT16_32280	COG2207	Transcriptional regulator
VspSTUT16_32290	COG1979	alcohol dehydrogenase
VspSTUT16_32340	COG2271	Major facilitator Superfamily
VspSTUT16_32350	COG0469	pyruvate kinase activity
VspSTUT16_32360	COG1126	abc transporter atp-binding protein
VspSTUT16_32370	COG0765	amino acid transport
VspSTUT16_32380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VspSTUT16_32390	COG0765	amino acid transport
VspSTUT16_32400	COG2199	diguanylate cyclase activity
VspSTUT16_32400	COG2203	Gaf domain
VspSTUT16_32400	COG2200	EAL domain
VspSTUT16_32430	COG1609	Transcriptional regulator
VspSTUT16_32440	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VspSTUT16_32440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VspSTUT16_32450	COG1105	Belongs to the carbohydrate kinase PfkB family
VspSTUT16_32460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VspSTUT16_32460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VspSTUT16_32460	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
VspSTUT16_32500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VspSTUT16_32520	COG0404	The glycine cleavage system catalyzes the degradation of glycine
VspSTUT16_32540	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VspSTUT16_32550	COG0509	glycine decarboxylation via glycine cleavage system
VspSTUT16_32560	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VspSTUT16_32560	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VspSTUT16_32570	COG0346	lactoylglutathione lyase activity
VspSTUT16_32580	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
VspSTUT16_32620	COG2176	DNA-directed DNA polymerase activity
VspSTUT16_32710	COG0242	peptide deformylase activity
VspSTUT16_32750	COG2239	Acts as a magnesium transporter
VspSTUT16_32790	COG0346	lactoylglutathione lyase activity
VspSTUT16_32800	COG1902	pentaerythritol trinitrate reductase activity
VspSTUT16_32840	COG5642	Protein of unknown function (DUF2384)
VspSTUT16_32850	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
VspSTUT16_32970	COG2962	Rard protein
VspSTUT16_33000	COG0835	chemotaxis
VspSTUT16_33000	COG0784	Response regulator, receiver
VspSTUT16_33010	COG2197	response regulator
VspSTUT16_33030	COG3706	GGDEF domain
VspSTUT16_33050	COG2200	EAL domain
VspSTUT16_33050	COG2199	diguanylate cyclase activity
VspSTUT16_33070	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
VspSTUT16_33110	COG0456	acetyltransferase
VspSTUT16_33110	COG1214	PFAM Peptidase M22, glycoprotease
VspSTUT16_33140	COG3069	C4-dicarboxylate transmembrane transporter activity
VspSTUT16_33150	COG1704	LemA family
VspSTUT16_33160	COG0501	Belongs to the peptidase M48B family
VspSTUT16_33210	COG3111	PFAM Bacterial OB fold (BOF) protein
VspSTUT16_33220	COG1597	lipid kinase activity
VspSTUT16_33230	COG0583	DNA-binding transcription factor activity
VspSTUT16_33240	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VspSTUT16_33240	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VspSTUT16_33300	COG0714	Associated with various cellular activities
VspSTUT16_33310	COG0641	radical SAM
VspSTUT16_33320	COG3119	arylsulfatase activity
VspSTUT16_33340	COG3119	arylsulfatase activity
VspSTUT16_33380	COG2198	Histidine kinase
VspSTUT16_33380	COG0784	Response regulator, receiver
VspSTUT16_33380	COG2205	protein histidine kinase activity
VspSTUT16_33390	COG1879	ABC-type sugar transport system periplasmic component
VspSTUT16_33400	COG1803	Methylglyoxal synthase
VspSTUT16_33410	COG0210	DNA helicase
VspSTUT16_33420	COG1289	transmembrane transporter activity
VspSTUT16_33480	COG1629	transport
VspSTUT16_33480	COG4771	TonB-dependent receptor
VspSTUT16_33490	COG2207	Transcriptional regulator
VspSTUT16_33500	COG0789	Transcriptional regulator
VspSTUT16_33510	COG4604	ABC transporter, ATP-binding protein
VspSTUT16_33520	COG4605	iron ion homeostasis
VspSTUT16_33530	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VspSTUT16_33540	COG4607	ABC-type enterochelin transport system periplasmic component
VspSTUT16_33580	COG1609	Transcriptional regulator
VspSTUT16_33590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VspSTUT16_33600	COG1879	ABC-type sugar transport system periplasmic component
VspSTUT16_33610	COG1172	Belongs to the binding-protein-dependent transport system permease family
VspSTUT16_33620	COG1129	ABC transporter
VspSTUT16_33630	COG1869	D-ribose catabolic process
VspSTUT16_33640	COG5001	Diguanylate cyclase
VspSTUT16_33740	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
VspSTUT16_33760	COG0784	Response regulator, receiver
VspSTUT16_33760	COG2205	protein histidine kinase activity
VspSTUT16_33790	COG3300	MHYT domain
VspSTUT16_33790	COG5001	Diguanylate cyclase
VspSTUT16_33820	COG0330	HflC and HflK could
VspSTUT16_33850	COG0517	IMP dehydrogenase activity
VspSTUT16_33850	COG4175	Glycine betaine
VspSTUT16_33860	COG4176	ABC-type proline glycine betaine transport system permease component
VspSTUT16_33890	COG1012	belongs to the aldehyde dehydrogenase family
VspSTUT16_33900	COG1309	transcriptional regulator
VspSTUT16_33920	COG1028	Short-chain dehydrogenase reductase Sdr
VspSTUT16_33950	COG1024	Enoyl-CoA hydratase
VspSTUT16_33960	COG1960	acyl-CoA dehydrogenase activity
VspSTUT16_33980	COG0183	Belongs to the thiolase family
VspSTUT16_34000	COG1960	acyl-CoA dehydrogenase activity
VspSTUT16_34010	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
VspSTUT16_34020	COG1024	Enoyl-CoA hydratase
VspSTUT16_34050	COG2205	protein histidine kinase activity
VspSTUT16_34050	COG3437	response regulator, receiver
VspSTUT16_34050	COG3850	Histidine kinase
VspSTUT16_34050	COG4999	Histidine kinase
VspSTUT16_34080	COG0110	maltose O-acetyltransferase activity
VspSTUT16_34090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VspSTUT16_34100	COG1271	oxidase subunit
VspSTUT16_34110	COG1294	oxidase, subunit
VspSTUT16_34130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VspSTUT16_34150	COG3527	Alpha-acetolactate decarboxylase
VspSTUT16_34180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VspSTUT16_34310	COG1022	Amp-dependent synthetase and ligase
VspSTUT16_34360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VspSTUT16_34370	COG1263	PTS System
VspSTUT16_34370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VspSTUT16_34380	COG1486	melibiose metabolic process
VspSTUT16_34390	COG2188	Transcriptional regulator
VspSTUT16_34400	COG1320	monovalent cation:proton antiporter activity
VspSTUT16_34410	COG2212	antiporter activity
VspSTUT16_34420	COG1863	multisubunit Na H antiporter MnhE subunit
VspSTUT16_34430	COG0651	ATP synthesis coupled electron transport
VspSTUT16_34440	COG1006	Multisubunit Na H antiporter MnhC subunit
VspSTUT16_34450	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VspSTUT16_34450	COG2111	Na H antiporter
VspSTUT16_34470	COG0589	response to stress
VspSTUT16_34480	COG4221	oxidoreductase activity
VspSTUT16_34490	COG0583	DNA-binding transcription factor activity
VspSTUT16_34510	COG2814	Major facilitator Superfamily
VspSTUT16_34550	COG0583	DNA-binding transcription factor activity
VspSTUT16_34560	COG0674	pyruvate-flavodoxin oxidoreductase activity
VspSTUT16_34560	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
VspSTUT16_34570	COG1013	pyruvate-flavodoxin oxidoreductase activity
VspSTUT16_34600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VspSTUT16_34700	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
VspSTUT16_34720	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
VspSTUT16_34720	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
VspSTUT16_34750	COG4989	oxidoreductase activity
VspSTUT16_34780	COG0038	chloride channel
VspSTUT16_34800	COG1914	H( )-stimulated, divalent metal cation uptake system
VspSTUT16_34830	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VspSTUT16_34860	COG2897	thiosulfate sulfurtransferase activity
VspSTUT16_34900	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
VspSTUT16_34910	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VspSTUT16_34920	COG0840	transmembrane signaling receptor activity
VspSTUT16_34930	COG2814	Major facilitator Superfamily
VspSTUT16_34940	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VspSTUT16_34960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VspSTUT16_34980	COG0840	transmembrane signaling receptor activity
VspSTUT16_35020	COG2195	Cleaves the N-terminal amino acid of tripeptides
VspSTUT16_35050	COG2197	response regulator
VspSTUT16_35060	COG3850	Histidine kinase
VspSTUT16_35080	COG0243	molybdopterin cofactor binding
VspSTUT16_35100	COG3005	denitrification pathway
VspSTUT16_35120	COG3243	poly(R)-hydroxyalkanoic acid synthase
VspSTUT16_35140	COG0183	Belongs to the thiolase family
VspSTUT16_35160	COG1280	lysine exporter protein (LysE YggA)
VspSTUT16_35180	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VspSTUT16_35190	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VspSTUT16_35300	COG0784	Response regulator, receiver
VspSTUT16_35300	COG2205	protein histidine kinase activity
VspSTUT16_35310	COG1879	ABC-type sugar transport system periplasmic component
VspSTUT16_35320	COG2827	Endonuclease containing a URI domain
VspSTUT16_35330	COG3132	Protein of unknown function, DUF480
VspSTUT16_35370	COG0784	Response regulator, receiver
VspSTUT16_35370	COG2205	protein histidine kinase activity
VspSTUT16_35370	COG5002	protein histidine kinase activity
VspSTUT16_35420	COG0583	DNA-binding transcription factor activity
VspSTUT16_35440	COG0531	amino acid
VspSTUT16_35470	COG2205	protein histidine kinase activity
VspSTUT16_35480	COG0745	RESPONSE REGULATOR receiver
VspSTUT16_35540	COG1566	PFAM secretion protein HlyD family protein
VspSTUT16_35550	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
VspSTUT16_35560	COG2239	Acts as a magnesium transporter
VspSTUT16_35570	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
VspSTUT16_35580	COG0402	S-adenosylhomocysteine deaminase activity
VspSTUT16_35590	COG1418	mRNA catabolic process
VspSTUT16_35610	COG2814	Major facilitator Superfamily
VspSTUT16_35630	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VspSTUT16_35670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VspSTUT16_35700	COG0745	RESPONSE REGULATOR receiver
VspSTUT16_35710	COG2205	protein histidine kinase activity
VspSTUT16_35730	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VspSTUT16_35750	COG2194	sulfuric ester hydrolase activity
VspSTUT16_35800	COG4667	esterase of the alpha-beta hydrolase superfamily
VspSTUT16_35810	COG1741	Belongs to the pirin family
VspSTUT16_35820	COG1278	Cold shock
VspSTUT16_35850	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VspSTUT16_35880	COG1686	Belongs to the peptidase S11 family
VspSTUT16_35900	COG0625	glutathione transferase activity
VspSTUT16_35910	COG1621	beta-fructofuranosidase activity
VspSTUT16_35920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VspSTUT16_35930	COG1263	PTS System
VspSTUT16_35930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VspSTUT16_35990	COG1028	Short-chain dehydrogenase reductase Sdr
VspSTUT16_36020	COG3746	phosphate-selective porin O and P
VspSTUT16_36060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VspSTUT16_36060	COG2207	Transcriptional regulator
VspSTUT16_36070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VspSTUT16_36140	COG0513	Belongs to the DEAD box helicase family
VspSTUT16_36160	COG0583	DNA-binding transcription factor activity
VspSTUT16_36190	COG1902	pentaerythritol trinitrate reductase activity
VspSTUT16_36200	COG1063	alcohol dehydrogenase
VspSTUT16_36220	COG1028	Short-chain dehydrogenase reductase Sdr
VspSTUT16_36230	COG2207	Transcriptional regulator
VspSTUT16_36240	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VspSTUT16_36250	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VspSTUT16_36260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VspSTUT16_36270	COG0006	proline dipeptidase activity
VspSTUT16_36280	COG3608	succinylglutamate desuccinylase aspartoacylase
VspSTUT16_36290	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VspSTUT16_36300	COG1522	sequence-specific DNA binding
VspSTUT16_36310	COG1012	belongs to the aldehyde dehydrogenase family
VspSTUT16_36320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
VspSTUT16_36330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
VspSTUT16_36340	COG2423	ornithine cyclodeaminase activity
VspSTUT16_36360	COG3122	Protein conserved in bacteria
VspSTUT16_36370	COG1280	lysine exporter protein (LysE YggA)
VspSTUT16_36390	COG0583	DNA-binding transcription factor activity
VspSTUT16_36400	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VspSTUT16_36410	COG0252	asparaginase activity
VspSTUT16_36420	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
VspSTUT16_36450	COG2197	response regulator
VspSTUT16_36460	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VspSTUT16_36490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VspSTUT16_36530	COG3385	transposase activity
VspSTUT16_36540	COG3385	transposase activity
VspSTUT16_36550	COG3385	transposase activity
VspSTUT16_36560	COG1132	(ABC) transporter
VspSTUT16_36570	COG4774	siderophore transport
VspSTUT16_36580	COG1120	ATPase activity
VspSTUT16_36590	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
VspSTUT16_36660	COG2197	response regulator
VspSTUT16_36680	COG0840	transmembrane signaling receptor activity
VspSTUT16_36690	COG0714	Associated with various cellular activities
VspSTUT16_36720	COG2304	oxidoreductase activity
VspSTUT16_36730	COG2304	oxidoreductase activity
VspSTUT16_36760	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VspSTUT16_36770	COG0581	inorganic phosphate transmembrane transporter activity
VspSTUT16_36780	COG0573	inorganic phosphate transmembrane transporter activity
VspSTUT16_36840	COG4771	TonB-dependent receptor
VspSTUT16_36850	COG1770	oligopeptidase
VspSTUT16_36860	COG0513	Belongs to the DEAD box helicase family
VspSTUT16_36880	COG1388	LysM domain
VspSTUT16_36880	COG1376	ErfK ybiS ycfS ynhG family protein
VspSTUT16_36890	COG0415	Belongs to the DNA photolyase family
VspSTUT16_36900	COG0789	Transcriptional regulator
VspSTUT16_36910	COG3272	Protein of unknown function (DUF1722)
VspSTUT16_36920	COG0813	purine-nucleoside phosphorylase activity
VspSTUT16_36970	COG1566	PFAM secretion protein HlyD family protein
VspSTUT16_36980	COG4720	Psort location CytoplasmicMembrane, score
VspSTUT16_36990	COG1122	ATPase activity
VspSTUT16_37030	COG0348	domain, Protein
VspSTUT16_37040	COG0437	4 iron, 4 sulfur cluster binding
VspSTUT16_37050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VspSTUT16_37090	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VspSTUT16_37100	COG0840	transmembrane signaling receptor activity
VspSTUT16_37110	COG1067	ATP-dependent peptidase activity
VspSTUT16_37130	COG4172	Belongs to the ABC transporter superfamily
VspSTUT16_37140	COG1505	serine-type exopeptidase activity
VspSTUT16_37150	COG0583	DNA-binding transcription factor activity
VspSTUT16_37160	COG1620	l-lactate permease
VspSTUT16_37170	COG1304	FMN binding
VspSTUT16_37190	COG0668	transmembrane transport
VspSTUT16_37260	COG1063	alcohol dehydrogenase
VspSTUT16_37270	COG0156	8-amino-7-oxononanoate synthase activity
VspSTUT16_37280	COG3300	MHYT domain
VspSTUT16_37280	COG5001	Diguanylate cyclase
VspSTUT16_37290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VspSTUT16_37340	COG0745	RESPONSE REGULATOR receiver
VspSTUT16_37390	COG0346	lactoylglutathione lyase activity
VspSTUT16_37500	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VspSTUT16_37580	COG1987	bacterial-type flagellum assembly
VspSTUT16_37600	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
VspSTUT16_37630	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VspSTUT16_37650	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VspSTUT16_37660	COG1516	flagellar protein fliS
VspSTUT16_37690	COG1580	Controls the rotational direction of flagella during chemotaxis
VspSTUT16_37700	COG1191	sigma factor activity
VspSTUT16_37710	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VspSTUT16_37720	COG1360	Flagellar Motor Protein
VspSTUT16_37810	COG1882	Formate acetyltransferase
VspSTUT16_37820	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VspSTUT16_37830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
VspSTUT16_37850	COG0454	-acetyltransferase
VspSTUT16_37870	COG2814	Major facilitator Superfamily
VspSTUT16_37940	COG1566	PFAM secretion protein HlyD family protein
VspSTUT16_37960	COG0628	permease
VspSTUT16_37970	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VspSTUT16_38000	COG4628	conserved protein (DUF2132)
VspSTUT16_38010	COG0583	DNA-binding transcription factor activity
VspSTUT16_38060	COG1686	Belongs to the peptidase S11 family
VspSTUT16_38090	COG1054	Belongs to the UPF0176 family
VspSTUT16_38110	COG0415	Belongs to the DNA photolyase family
VspSTUT16_38120	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
VspSTUT16_38130	COG3397	chitin binding
VspSTUT16_38140	COG4667	esterase of the alpha-beta hydrolase superfamily
VspSTUT16_38150	COG2095	MarC family integral membrane protein
VspSTUT16_38180	COG1596	polysaccharide export
VspSTUT16_38220	COG1301	dicarboxylic acid transport
VspSTUT16_38230	COG3339	Conserved Protein
VspSTUT16_38240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VspSTUT16_38250	COG0700	Nucleoside recognition
VspSTUT16_38260	COG3366	ferrous iron transmembrane transporter activity
VspSTUT16_38280	COG0366	Alpha amylase catalytic
VspSTUT16_38290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VspSTUT16_38300	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
VspSTUT16_38310	COG1640	4-alpha-glucanotransferase
VspSTUT16_38320	COG0058	SHG alpha-glucan phosphorylase activity
VspSTUT16_38330	COG2909	trisaccharide binding
VspSTUT16_38360	COG1999	signal sequence binding
VspSTUT16_38370	COG1263	PTS System
VspSTUT16_38370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VspSTUT16_38380	COG1162	GTPase activity
VspSTUT16_38390	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
VspSTUT16_38400	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
VspSTUT16_38420	COG0531	amino acid
VspSTUT16_38430	COG1982	Orn Lys Arg decarboxylase major
VspSTUT16_38470	COG2356	endonuclease I
VspSTUT16_38530	COG1760	l-serine dehydratase
VspSTUT16_38580	COG1609	Transcriptional regulator
VspSTUT16_38650	COG0739	heme binding
VspSTUT16_38670	COG0612	Peptidase, M16
VspSTUT16_38680	COG0840	transmembrane signaling receptor activity
VspSTUT16_38690	COG1120	ATPase activity
VspSTUT16_38700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VspSTUT16_38710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VspSTUT16_38720	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
VspSTUT16_38730	COG4772	TonB-dependent receptor
VspSTUT16_38790	COG4264	IucA IucC family
VspSTUT16_38800	COG0019	diaminopimelate decarboxylase activity
VspSTUT16_38810	COG1653	transport
VspSTUT16_38860	COG0826	peptidase U32
VspSTUT16_38870	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VspSTUT16_38890	COG0463	Glycosyl transferase, family 2
VspSTUT16_38930	COG1136	(ABC) transporter
VspSTUT16_38940	COG0577	efflux transmembrane transporter activity
VspSTUT16_38970	COG1764	response to oxidative stress
VspSTUT16_38980	COG1846	Transcriptional regulator
VspSTUT16_39000	COG3634	alkyl hydroperoxide reductase activity
VspSTUT16_39050	COG1595	DNA-templated transcription, initiation
VspSTUT16_39090	COG2258	MOSC domain
VspSTUT16_39130	COG2207	Transcriptional regulator
VspSTUT16_39150	COG1132	(ABC) transporter
VspSTUT16_39220	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VspSTUT16_39270	COG0259	pyridoxamine-phosphate oxidase activity
VspSTUT16_39360	COG4166	transmembrane transport
VspSTUT16_39390	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VspSTUT16_39400	COG1263	PTS System
VspSTUT16_39400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VspSTUT16_39410	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VspSTUT16_39420	COG3340	Belongs to the peptidase S51 family
VspSTUT16_39460	COG1444	tRNA N-acetyltransferase activity
VspSTUT16_39510	COG4608	Belongs to the ABC transporter superfamily
VspSTUT16_39520	COG0444	Belongs to the ABC transporter superfamily
VspSTUT16_39540	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VspSTUT16_39540	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
VspSTUT16_39590	COG0772	Belongs to the SEDS family
VspSTUT16_39610	COG1136	(ABC) transporter
VspSTUT16_39650	COG3275	phosphorelay sensor kinase activity
VspSTUT16_39660	COG3279	Response regulator of the LytR AlgR family
VspSTUT16_39680	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VspSTUT16_39720	COG0786	glutamate:sodium symporter activity
VspSTUT16_39740	COG1131	(ABC) transporter
VspSTUT16_39750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VspSTUT16_39760	COG0786	glutamate:sodium symporter activity
VspSTUT16_39780	COG0363	glucosamine-6-phosphate deaminase activity
VspSTUT16_39820	COG1741	Belongs to the pirin family
VspSTUT16_39830	COG2259	Doxx family
VspSTUT16_39850	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
VspSTUT16_39880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
VspSTUT16_39930	COG0596	Alpha beta hydrolase
VspSTUT16_39960	COG3123	guanosine phosphorylase activity
VspSTUT16_39990	COG0534	Mate efflux family protein
VspSTUT16_40000	COG0564	pseudouridine synthase activity
VspSTUT16_40030	COG0583	DNA-binding transcription factor activity
VspSTUT16_40040	COG0561	phosphatase activity
VspSTUT16_40060	COG2199	diguanylate cyclase activity
VspSTUT16_40090	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
VspSTUT16_40100	COG2162	N-hydroxyarylamine O-acetyltransferase activity
VspSTUT16_40110	COG0583	DNA-binding transcription factor activity
VspSTUT16_40120	COG2375	cellular response to nickel ion
VspSTUT16_40190	COG1357	PFAM Pentapeptide repeats (8 copies)
VspSTUT16_40200	COG3047	cAMP biosynthetic process
VspSTUT16_40260	COG3408	Glycogen debranching enzyme
VspSTUT16_40260	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
VspSTUT16_40270	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
VspSTUT16_40300	COG0583	DNA-binding transcription factor activity
VspSTUT16_40320	COG0583	DNA-binding transcription factor activity
VspSTUT16_40350	COG0546	phosphoglycolate phosphatase activity
VspSTUT16_40400	COG3835	regulator
VspSTUT16_40410	COG2610	gluconate transmembrane transporter activity
VspSTUT16_40420	COG1929	Belongs to the glycerate kinase type-1 family
VspSTUT16_40430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VspSTUT16_40470	COG0456	acetyltransferase
VspSTUT16_40500	COG1028	Short-chain dehydrogenase reductase Sdr
VspSTUT16_40510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VspSTUT16_40520	COG3005	denitrification pathway
VspSTUT16_40530	COG0243	molybdopterin cofactor binding
VspSTUT16_40550	COG0352	thiamine-phosphate diphosphorylase activity
VspSTUT16_40560	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
VspSTUT16_40570	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
VspSTUT16_40580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
VspSTUT16_40590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
VspSTUT16_40600	COG1116	anion transmembrane transporter activity
VspSTUT16_40610	COG0351	phosphomethylpyrimidine kinase
VspSTUT16_40620	COG0312	modulator of DNA gyrase
VspSTUT16_40630	COG0312	modulator of DNA gyrase
VspSTUT16_40640	COG1901	pseudouridine methyltransferase
VspSTUT16_40690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VspSTUT16_40710	COG0584	glycerophosphoryl diester phosphodiesterase
VspSTUT16_40720	COG0039	L-malate dehydrogenase activity
VspSTUT16_40730	COG0745	RESPONSE REGULATOR receiver
VspSTUT16_40770	COG0811	peptide transport
VspSTUT16_40780	COG0811	peptide transport
VspSTUT16_40790	COG0848	biopolymer transport protein
VspSTUT16_40880	COG0803	Belongs to the bacterial solute-binding protein 9 family
VspSTUT16_40890	COG1121	(ABC) transporter
VspSTUT16_40900	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VspSTUT16_40930	COG1770	oligopeptidase
VspSTUT16_40940	COG2814	Major facilitator Superfamily
VspSTUT16_40950	COG0010	Belongs to the arginase family
VspSTUT16_40960	COG1166	arginine decarboxylase activity
VspSTUT16_40980	COG4067	protein conserved in archaea
VspSTUT16_40980	COG0189	ligase activity
VspSTUT16_40990	COG0189	ligase activity
VspSTUT16_41000	COG0583	DNA-binding transcription factor activity
VspSTUT16_41070	COG4191	Histidine kinase
VspSTUT16_41080	COG2204	response regulator
VspSTUT16_41090	COG3706	GGDEF domain
VspSTUT16_41130	COG0579	oxidoreductase
VspSTUT16_41170	COG1294	oxidase, subunit
VspSTUT16_41180	COG1271	oxidase subunit
VspSTUT16_41200	COG3033	Beta-eliminating lyase
VspSTUT16_41220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VspSTUT16_41250	COG3706	GGDEF domain
VspSTUT16_41280	COG3706	GGDEF domain
VspSTUT16_41290	COG0415	Belongs to the DNA photolyase family
VspSTUT16_41300	COG3046	protein related to deoxyribodipyrimidine photolyase
VspSTUT16_41320	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VspSTUT16_41320	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VspSTUT16_41330	COG1765	OsmC-like protein
VspSTUT16_41340	COG0110	maltose O-acetyltransferase activity
VspSTUT16_41420	COG1011	Hydrolase
VspSTUT16_41450	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VspSTUT16_41470	COG2067	long-chain fatty acid transport protein
VspSTUT16_41480	COG3240	lipase activity
VspSTUT16_41540	COG1609	Transcriptional regulator
VspSTUT16_41550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VspSTUT16_41560	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VspSTUT16_41580	COG1840	ABC-type Fe3 transport system, periplasmic component
VspSTUT16_41590	COG3842	ATPase activity
VspSTUT16_41640	COG2990	Protein conserved in bacteria
VspSTUT16_41660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VspSTUT16_41670	COG2866	Carboxypeptidase
VspSTUT16_41690	COG0583	DNA-binding transcription factor activity
VspSTUT16_41730	COG3104	oligopeptide transport
VspSTUT16_41740	COG1760	l-serine dehydratase
VspSTUT16_41780	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
VspSTUT16_41790	COG0741	lytic transglycosylase activity
VspSTUT16_41830	COG1815	bacterial-type flagellum-dependent cell motility
VspSTUT16_41840	COG1558	bacterial-type flagellum-dependent cell motility
VspSTUT16_41850	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
VspSTUT16_41860	COG1749	Flagellar hook protein flgE
VspSTUT16_41870	COG4787	bacterial-type flagellum-dependent cell motility
VspSTUT16_41880	COG4786	Flagellar basal body rod
VspSTUT16_41890	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VspSTUT16_41900	COG1706	bacterial-type flagellum-dependent cell motility
VspSTUT16_41920	COG1256	bacterial-type flagellum assembly
VspSTUT16_41920	COG4786	Flagellar basal body rod
VspSTUT16_41930	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VspSTUT16_41970	COG1304	FMN binding
VspSTUT16_42000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VspSTUT16_42010	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VspSTUT16_42020	COG0459	protein refolding
VspSTUT16_42080	COG1309	transcriptional regulator
VspSTUT16_42100	COG4303	Ethanolamine ammonia lyase large subunit
VspSTUT16_42110	COG4302	ethanolamine ammonia-lyase activity
VspSTUT16_42120	COG0531	amino acid
VspSTUT16_42140	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VspSTUT16_42170	COG0346	lactoylglutathione lyase activity
VspSTUT16_42180	COG1349	DNA-binding transcription factor activity
VspSTUT16_42200	COG1335	isochorismatase
VspSTUT16_42220	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
VspSTUT16_42270	COG0583	DNA-binding transcription factor activity
VspSTUT16_42300	COG3713	MltA-interacting MipA family protein
VspSTUT16_42310	COG3015	lipoprotein NlpE involved in copper resistance
VspSTUT16_42320	COG3448	diguanylate cyclase activity
VspSTUT16_42320	COG4175	Glycine betaine
VspSTUT16_42330	COG4176	ABC-type proline glycine betaine transport system permease component
VspSTUT16_42340	COG1342	Belongs to the UPF0251 family
VspSTUT16_42400	COG4948	Mandelate Racemase Muconate Lactonizing
VspSTUT16_42420	COG0583	DNA-binding transcription factor activity
VspSTUT16_42490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VspSTUT16_42550	COG3842	ATPase activity
VspSTUT16_42610	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VspSTUT16_42630	COG0583	DNA-binding transcription factor activity
VspSTUT16_42660	COG1012	belongs to the aldehyde dehydrogenase family
VspSTUT16_42670	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VspSTUT16_42680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VspSTUT16_42700	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VspSTUT16_42710	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
VspSTUT16_42720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VspSTUT16_42780	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VspSTUT16_42780	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VspSTUT16_42780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VspSTUT16_42790	COG2207	Transcriptional regulator
VspSTUT16_42810	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VspSTUT16_42820	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VspSTUT16_42830	COG2084	Dehydrogenase
VspSTUT16_42840	COG0753	catalase activity
VspSTUT16_42860	COG2130	NADP-dependent
VspSTUT16_42870	COG1309	transcriptional regulator
VspSTUT16_42880	COG3097	Belongs to the UPF0267 family
VspSTUT16_42990	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VspSTUT16_43000	COG3842	ATPase activity
VspSTUT16_43020	COG1175	transmembrane transport
VspSTUT16_43030	COG3833	ABC-type maltose transport systems, permease component
VspSTUT16_43090	COG2354	Protein conserved in bacteria
VspSTUT16_43100	COG0418	dihydroorotase activity
VspSTUT16_43110	COG0401	homolog of Blt101
VspSTUT16_43120	COG0633	Ferredoxin
VspSTUT16_43120	COG3217	Mosc domain protein beta barrel domain protein
VspSTUT16_43120	COG0633	Ferredoxin
VspSTUT16_43120	COG3217	Mosc domain protein beta barrel domain protein
VspSTUT16_43130	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
VspSTUT16_43140	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
VspSTUT16_43220	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
VspSTUT16_43230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VspSTUT16_43250	COG0848	biopolymer transport protein
VspSTUT16_43260	COG0811	peptide transport
VspSTUT16_43270	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VspSTUT16_43290	COG3721	Heme iron utilization protein
VspSTUT16_43300	COG0748	coenzyme F420 binding
VspSTUT16_43320	COG0835	chemotaxis
VspSTUT16_43320	COG0784	Response regulator, receiver
VspSTUT16_43330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VspSTUT16_43400	COG0583	DNA-binding transcription factor activity
VspSTUT16_43410	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VspSTUT16_43430	COG4934	collagen metabolic process
VspSTUT16_43460	COG0789	Transcriptional regulator
VspSTUT16_43470	COG0366	Alpha amylase catalytic
VspSTUT16_43510	COG2249	NAD(P)H dehydrogenase (quinone) activity
VspSTUT16_43520	COG0589	response to stress
VspSTUT16_43530	COG0488	(ABC) transporter
VspSTUT16_43540	COG1505	serine-type exopeptidase activity
VspSTUT16_43560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VspSTUT16_43580	COG2067	long-chain fatty acid transport protein
VspSTUT16_43600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VspSTUT16_43670	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VspSTUT16_43710	COG3383	formate dehydrogenase (NAD+) activity
VspSTUT16_43740	COG0842	Transport permease protein
VspSTUT16_43750	COG1131	(ABC) transporter
VspSTUT16_43780	COG2706	6-phosphogluconolactonase activity
VspSTUT16_43800	COG1881	PFAM PEBP family protein
VspSTUT16_43820	COG0798	PFAM Bile acid sodium symporter
VspSTUT16_43850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VspSTUT16_43860	COG2213	PTS system mannitol-specific
VspSTUT16_43870	COG1063	alcohol dehydrogenase
VspSTUT16_43890	COG1072	(Pantothenic acid kinase))
VspSTUT16_43900	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
VspSTUT16_43930	COG0814	amino acid
VspSTUT16_43950	COG0840	transmembrane signaling receptor activity
VspSTUT16_43960	COG3314	Sporulation integral membrane protein YlbJ
VspSTUT16_44000	COG0739	heme binding
VspSTUT16_44010	COG5001	Diguanylate cyclase
VspSTUT16_44020	COG0583	DNA-binding transcription factor activity
VspSTUT16_44030	COG2814	Major facilitator Superfamily
VspSTUT16_44070	COG0697	spore germination
VspSTUT16_44110	COG0179	Fumarylacetoacetate (FAA) hydrolase
VspSTUT16_44150	COG1280	lysine exporter protein (LysE YggA)
VspSTUT16_44170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VspSTUT16_44190	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
VspSTUT16_44200	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
VspSTUT16_44210	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
VspSTUT16_44260	COG1612	heme a metabolic process
VspSTUT16_44270	COG0109	protoheme IX farnesyltransferase activity
VspSTUT16_44280	COG0545	Peptidyl-prolyl cis-trans isomerase
VspSTUT16_44300	COG2885	chlorophyll binding
VspSTUT16_44460	COG4695	Portal protein
VspSTUT16_44490	COG3772	lysozyme
VspSTUT16_44560	COG4381	Mu-like prophage protein gp46
VspSTUT16_44780	COG1278	Cold shock
VspSTUT16_44790	COG3036	rescue of stalled ribosome
VspSTUT16_44800	COG2199	diguanylate cyclase activity
VspSTUT16_44840	COG0577	efflux transmembrane transporter activity
VspSTUT16_44840	COG1136	(ABC) transporter
VspSTUT16_44870	COG0783	Belongs to the Dps family
VspSTUT16_44890	COG2133	pyrroloquinoline quinone binding
VspSTUT16_44900	COG1454	alcohol dehydrogenase
VspSTUT16_44910	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
VspSTUT16_44960	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VspSTUT16_44970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VspSTUT16_44980	COG3186	Phenylalanine-4-hydroxylase
VspSTUT16_45030	COG3530	Putative quorum-sensing-regulated virulence factor
VspSTUT16_45060	COG1404	Belongs to the peptidase S8 family
VspSTUT16_45150	COG3344	reverse transcriptase
VspSTUT16_45180	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
VspSTUT16_45190	COG2207	Transcriptional regulator
VspSTUT16_45280	COG0583	DNA-binding transcription factor activity
VspSTUT16_45300	COG0730	response to heat
VspSTUT16_45310	COG0513	Belongs to the DEAD box helicase family
VspSTUT16_45320	COG4628	conserved protein (DUF2132)
VspSTUT16_45340	COG0133	tryptophan synthase activity
VspSTUT16_45350	COG0557	exoribonuclease II activity
VspSTUT16_45360	COG1278	Cold shock
VspSTUT16_45380	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
VspSTUT16_45400	COG0523	cobalamin synthesis protein
VspSTUT16_45410	COG0513	Belongs to the DEAD box helicase family
VspSTUT16_45450	COG2200	EAL domain
VspSTUT16_45460	COG1119	ATPase activity
VspSTUT16_45470	COG0840	transmembrane signaling receptor activity
VspSTUT16_45590	COG0582	viral genome integration into host DNA
VspSTUT16_45640	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
VspSTUT16_45650	COG0513	Belongs to the DEAD box helicase family
VspSTUT16_45670	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VspSTUT16_45770	COG3618	amidohydrolase
VspSTUT16_45780	COG0277	FAD linked oxidase domain protein
VspSTUT16_45780	COG0247	lactate metabolic process
VspSTUT16_45800	COG5413	integral membrane protein
VspSTUT16_45820	COG1024	Enoyl-CoA hydratase
VspSTUT16_45830	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
VspSTUT16_45840	COG1960	acyl-CoA dehydrogenase activity
VspSTUT16_45870	COG0183	Belongs to the thiolase family
VspSTUT16_45900	COG1024	Enoyl-CoA hydratase
VspSTUT16_45910	COG1024	Enoyl-CoA hydratase
VspSTUT16_45930	COG1028	Short-chain dehydrogenase reductase Sdr
VspSTUT16_45940	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
VspSTUT16_45950	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
VspSTUT16_45960	COG1845	cytochrome c oxidase, subunit III
VspSTUT16_45970	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
VspSTUT16_45980	COG0109	protoheme IX farnesyltransferase activity
VspSTUT16_45990	COG1902	pentaerythritol trinitrate reductase activity
VspSTUT16_45990	COG0446	pyridine nucleotide-disulphide oxidoreductase
VspSTUT16_46030	COG1012	belongs to the aldehyde dehydrogenase family
VspSTUT16_46050	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VspSTUT16_46110	COG1126	abc transporter atp-binding protein
VspSTUT16_46120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VspSTUT16_46130	COG4215	(ABC) transporter
VspSTUT16_46140	COG4160	amino acid transport
VspSTUT16_46270	COG0443	Heat shock 70 kDa protein
VspSTUT16_46280	COG2847	Copper chaperone PCu(A)C
VspSTUT16_46430	COG0814	amino acid
VspSTUT16_46460	COG0243	molybdopterin cofactor binding
VspSTUT16_46510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
VspSTUT16_46510	COG1116	anion transmembrane transporter activity
VspSTUT16_46520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
VspSTUT16_46530	COG1116	anion transmembrane transporter activity
VspSTUT16_46540	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VspSTUT16_46540	COG2146	nitrite reductase [NAD(P)H] activity
VspSTUT16_46580	COG0625	glutathione transferase activity
VspSTUT16_46640	COG2815	serine threonine protein kinase
VspSTUT16_46640	COG0515	serine threonine protein kinase
VspSTUT16_46710	COG0631	protein serine/threonine phosphatase activity
VspSTUT16_46850	COG0420	3'-5' exonuclease activity
VspSTUT16_46860	COG0419	ATPase involved in DNA repair
VspSTUT16_46880	COG3040	lipid binding
VspSTUT16_46900	COG1288	antiporter activity
VspSTUT16_46920	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
VspSTUT16_46950	COG2425	protein containing a von Willebrand factor type A (vWA) domain
VspSTUT16_46960	COG0583	DNA-binding transcription factor activity
VspSTUT16_46970	COG0277	FAD linked oxidase domain protein
VspSTUT16_47040	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VspSTUT16_47140	COG5001	Diguanylate cyclase
VspSTUT16_47150	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VspSTUT16_47160	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VspSTUT16_47180	COG2116	formate transmembrane transporter activity
VspSTUT16_47220	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VspSTUT16_47290	COG3118	belongs to the thioredoxin family
VspSTUT16_47300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VspSTUT16_47350	COG2271	Major facilitator Superfamily
VspSTUT16_47360	COG3851	Histidine kinase
VspSTUT16_47370	COG2197	response regulator
VspSTUT16_47390	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VspSTUT16_47400	COG0583	DNA-binding transcription factor activity
VspSTUT16_47410	COG0243	molybdopterin cofactor binding
VspSTUT16_47430	COG0384	phenazine biosynthesis protein PhzF
VspSTUT16_47440	COG1794	racemase activity, acting on amino acids and derivatives
VspSTUT16_47450	COG0446	pyridine nucleotide-disulphide oxidoreductase
VspSTUT16_47580	COG4735	regulation of single-species biofilm formation
VspSTUT16_47590	COG0443	Heat shock 70 kDa protein
VspSTUT16_47680	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
VspSTUT16_47710	COG3604	Transcriptional regulator
VspSTUT16_47750	COG1479	Protein of unknown function DUF262
VspSTUT16_47810	COG3344	reverse transcriptase
VspSTUT16_47860	COG2199	diguanylate cyclase activity
VspSTUT16_47950	COG0446	pyridine nucleotide-disulphide oxidoreductase
VspSTUT16_48000	COG3609	addiction module antidote protein, CC2985 family