locus-tag	class	description
GGC03_00010	COG0592	DNA-directed DNA polymerase activity
GGC03_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GGC03_00020	COG0187	DNA topoisomerase II activity
GGC03_00025	COG0071	Belongs to the small heat shock protein (HSP20) family
GGC03_00030	COG3977	Valine--pyruvate aminotransferase
GGC03_00035	COG0751	glycine-tRNA ligase activity
GGC03_00045	COG2119	membrane
GGC03_00055	COG0425	Belongs to the sulfur carrier protein TusA family
GGC03_00070	COG0604	alcohol dehydrogenase
GGC03_00080	COG0129	dihydroxy-acid dehydratase activity
GGC03_00085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GGC03_00090	COG3978	acetolactate synthase activity
GGC03_00100	COG0606	chelatase, subunit chli
GGC03_00190	COG0606	chelatase, subunit chli
GGC03_00200	COG0204	Acyl-transferase
GGC03_00205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GGC03_00210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GGC03_00220	COG3084	Protein conserved in bacteria
GGC03_00225	COG4326	sporulation control protein
GGC03_00230	COG1272	protein, Hemolysin III
GGC03_00240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GGC03_00245	COG0569	domain protein
GGC03_00250	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GGC03_00250	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GGC03_00260	COG0242	peptide deformylase activity
GGC03_00265	COG0758	DNA mediated transformation
GGC03_00270	COG2922	Belongs to the Smg family
GGC03_00275	COG0551	DNA topoisomerase type I activity
GGC03_00280	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GGC03_00285	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GGC03_00295	COG0408	coproporphyrinogen oxidase activity
GGC03_00310	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GGC03_00350	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GGC03_00360	COG2204	response regulator
GGC03_00365	COG3852	Histidine kinase
GGC03_00370	COG0174	glutamine synthetase
GGC03_00390	COG1490	D-aminoacyl-tRNA deacylase activity
GGC03_00395	COG0456	acetyltransferase
GGC03_00405	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GGC03_00415	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GGC03_00420	COG3031	protein transport across the cell outer membrane
GGC03_00430	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GGC03_00435	COG1459	type II secretion system
GGC03_00440	COG2165	general secretion pathway protein
GGC03_00445	COG2165	general secretion pathway protein
GGC03_00450	COG2165	general secretion pathway protein
GGC03_00455	COG4795	General secretion pathway protein
GGC03_00460	COG3156	type II secretion system protein K
GGC03_00465	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GGC03_00470	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GGC03_00485	COG0745	RESPONSE REGULATOR receiver
GGC03_00490	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GGC03_00500	COG2183	response to ionizing radiation
GGC03_00510	COG0596	Alpha beta hydrolase
GGC03_00520	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GGC03_00520	COG0316	Belongs to the HesB IscA family
GGC03_00525	COG0494	nUDIX hydrolase
GGC03_00530	COG1218	3'(2'),5'-bisphosphate nucleotidase
GGC03_00535	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GGC03_00540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GGC03_00545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GGC03_00560	COG1595	DNA-templated transcription, initiation
GGC03_00590	COG0848	biopolymer transport protein
GGC03_00600	COG2252	PERMEase
GGC03_00605	COG2831	hemolysin activation secretion protein
GGC03_00610	COG3210	domain, Protein
GGC03_00620	COG1561	YicC-like family, N-terminal region
GGC03_00630	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GGC03_00635	COG1560	Kdo2-lipid A biosynthetic process
GGC03_00640	COG1560	Kdo2-lipid A biosynthetic process
GGC03_00645	COG1309	transcriptional regulator
GGC03_00650	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GGC03_00655	COG2003	Belongs to the UPF0758 family
GGC03_00685	COG0859	PFAM glycosyl transferase family 9
GGC03_00690	COG0463	Glycosyl transferase, family 2
GGC03_00695	COG0859	PFAM glycosyl transferase family 9
GGC03_00700	COG3642	lipopolysaccharide core region biosynthetic process
GGC03_00715	COG1519	Transferase
GGC03_00730	COG0859	PFAM glycosyl transferase family 9
GGC03_00760	COG1086	Polysaccharide biosynthesis protein
GGC03_00765	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GGC03_00775	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
GGC03_00780	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GGC03_00790	COG2089	acid synthase
GGC03_00800	COG0318	PFAM AMP-dependent synthetase and ligase
GGC03_00810	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GGC03_00825	COG4310	Domain of unknown function (DUF2172)
GGC03_00835	COG2226	methyltransferase
GGC03_00870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GGC03_00875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GGC03_00880	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GGC03_00880	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GGC03_00885	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GGC03_00915	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GGC03_00925	COG1494	fructose-1,6-bisphosphatase
GGC03_00935	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GGC03_00940	COG0460	homoserine dehydrogenase
GGC03_00940	COG0527	aspartate kinase activity
GGC03_00945	COG0626	cystathionine gamma-synthase activity
GGC03_00955	COG0281	malic enzyme
GGC03_00965	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GGC03_00970	COG1609	Transcriptional regulator
GGC03_00975	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GGC03_01005	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GGC03_01010	COG1053	succinate dehydrogenase
GGC03_01015	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GGC03_01020	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GGC03_01055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GGC03_01070	COG1045	serine acetyltransferase
GGC03_01075	COG1695	Transcriptional regulator
GGC03_01080	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GGC03_01085	COG1573	uracil-dna glycosylase
GGC03_01090	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GGC03_01095	COG3068	Protein conserved in bacteria
GGC03_01100	COG1253	flavin adenine dinucleotide binding
GGC03_01115	COG0151	Belongs to the GarS family
GGC03_01125	COG0789	Transcriptional regulator
GGC03_01130	COG3706	GGDEF domain
GGC03_01135	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GGC03_01140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GGC03_01145	COG2264	protein methyltransferase activity
GGC03_01150	COG0439	Biotin carboxylase
GGC03_01155	COG0511	ligase activity, forming carbon-carbon bonds
GGC03_01160	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GGC03_01165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GGC03_01180	COG2814	Major facilitator Superfamily
GGC03_01185	COG2205	protein histidine kinase activity
GGC03_01185	COG0784	Response regulator, receiver
GGC03_01195	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GGC03_01205	COG2095	MarC family integral membrane protein
GGC03_01215	COG4232	protein-disulfide reductase activity
GGC03_01220	COG1438	arginine binding
GGC03_01225	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GGC03_01230	COG0540	Belongs to the ATCase OTCase family
GGC03_01240	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GGC03_01255	COG1288	antiporter activity
GGC03_01260	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GGC03_01265	COG1027	Aspartate ammonia-lyase
GGC03_01350	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GGC03_01370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GGC03_01375	COG3954	Phosphoribulokinase
GGC03_01385	COG0429	hydrolase of the alpha beta-hydrolase fold
GGC03_01395	COG0488	(ABC) transporter
GGC03_01415	COG1047	Peptidyl-prolyl cis-trans
GGC03_01425	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GGC03_01430	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GGC03_01435	COG0402	S-adenosylhomocysteine deaminase activity
GGC03_01440	COG0557	exoribonuclease II activity
GGC03_01445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GGC03_01450	COG0051	transcription antitermination factor activity, RNA binding
GGC03_01460	COG0088	Forms part of the polypeptide exit tunnel
GGC03_01480	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GGC03_01485	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GGC03_01515	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GGC03_01530	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GGC03_01545	COG1841	ribosomal large subunit assembly
GGC03_01555	COG0201	protein transport
GGC03_01565	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GGC03_01570	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GGC03_01585	COG0203	ribosomal protein L17
GGC03_01595	COG0545	Peptidyl-prolyl cis-trans isomerase
GGC03_01610	COG2153	protein acetylation
GGC03_01620	COG0737	Belongs to the 5'-nucleotidase family
GGC03_01625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GGC03_01625	COG1648	precorrin-2 dehydrogenase activity
GGC03_01640	COG3273	potassium ion transport
GGC03_01640	COG0471	metal ion transport
GGC03_01645	COG0529	Catalyzes the synthesis of activated sulfate
GGC03_01655	COG0735	belongs to the Fur family
GGC03_01665	COG3437	response regulator, receiver
GGC03_01695	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GGC03_01700	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GGC03_01760	COG0646	methionine synthase
GGC03_01760	COG1410	methionine synthase
GGC03_01765	COG2239	Acts as a magnesium transporter
GGC03_01770	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC03_01780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC03_01785	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GGC03_01795	COG1137	ATPase activity
GGC03_01800	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GGC03_01810	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GGC03_01815	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GGC03_01815	COG0517	IMP dehydrogenase activity
GGC03_01825	COG1127	ABC transporter
GGC03_01830	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GGC03_01835	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GGC03_01840	COG2854	intermembrane phospholipid transfer
GGC03_01850	COG5007	Belongs to the BolA IbaG family
GGC03_01860	COG0204	Acyl-transferase
GGC03_01865	COG2235	arginine
GGC03_01885	COG0589	response to stress
GGC03_01910	COG0039	L-malate dehydrogenase activity
GGC03_01920	COG0251	oxidation-reduction process
GGC03_01925	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GGC03_01940	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GGC03_01945	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GGC03_01955	COG0564	pseudouridine synthase activity
GGC03_01960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GGC03_01970	COG4269	membrane
GGC03_01980	COG0525	valine-tRNA ligase activity
GGC03_01985	COG2927	DNA polymerase III (CHI subunit)
GGC03_01995	COG0795	lipopolysaccharide-transporting ATPase activity
GGC03_02000	COG0795	lipopolysaccharide-transporting ATPase activity
GGC03_02005	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GGC03_02010	COG1546	Belongs to the CinA family
GGC03_02015	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GGC03_02020	COG2137	regulation of response to DNA damage stimulus
GGC03_02030	COG0527	aspartate kinase activity
GGC03_02080	COG3630	sodium ion export across plasma membrane
GGC03_02085	COG0511	ligase activity, forming carbon-carbon bonds
GGC03_02085	COG5016	pyruvate
GGC03_02090	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GGC03_02095	COG2130	NADP-dependent
GGC03_02100	COG1238	metal cluster binding
GGC03_02105	COG0612	Peptidase, M16
GGC03_02110	COG2918	glutathione biosynthetic process
GGC03_02120	COG1854	S-ribosylhomocysteine lyase activity
GGC03_02135	COG0582	viral genome integration into host DNA
GGC03_02165	COG0328	RNA-DNA hybrid ribonuclease activity
GGC03_02180	COG3547	Transposase (IS116 IS110 IS902 family)
GGC03_02200	COG5001	Diguanylate cyclase
GGC03_02200	COG3706	GGDEF domain
GGC03_02200	COG4251	negative regulation of phosphorylation
GGC03_02200	COG2203	Gaf domain
GGC03_02210	COG1879	ABC-type sugar transport system periplasmic component
GGC03_02215	COG0840	transmembrane signaling receptor activity
GGC03_02235	COG0840	transmembrane signaling receptor activity
GGC03_02240	COG4251	negative regulation of phosphorylation
GGC03_02240	COG5001	Diguanylate cyclase
GGC03_02240	COG2203	Gaf domain
GGC03_02240	COG3706	GGDEF domain
GGC03_02270	COG0640	Transcriptional regulator
GGC03_02310	COG2003	Belongs to the UPF0758 family
GGC03_02320	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GGC03_02350	COG3437	response regulator, receiver
GGC03_02410	COG0473	3-isopropylmalate dehydrogenase activity
GGC03_02415	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GGC03_02435	COG0583	DNA-binding transcription factor activity
GGC03_02440	COG1022	Amp-dependent synthetase and ligase
GGC03_02445	COG0028	Belongs to the TPP enzyme family
GGC03_02450	COG0440	acetolactate synthase activity
GGC03_02455	COG0584	glycerophosphoryl diester phosphodiesterase
GGC03_02460	COG2271	Major facilitator Superfamily
GGC03_02465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GGC03_02475	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GGC03_02485	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GGC03_02495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GGC03_02500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GGC03_02525	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GGC03_02530	COG1595	DNA-templated transcription, initiation
GGC03_02545	COG3086	response to oxidative stress
GGC03_02550	COG0481	GTPase activity
GGC03_02555	COG0681	Belongs to the peptidase S26 family
GGC03_02565	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GGC03_02570	COG1381	Involved in DNA repair and RecF pathway recombination
GGC03_02580	COG0736	holo-[acyl-carrier-protein] synthase activity
GGC03_02585	COG2205	protein histidine kinase activity
GGC03_02585	COG3437	response regulator, receiver
GGC03_02585	COG3850	Histidine kinase
GGC03_02585	COG4999	Histidine kinase
GGC03_02590	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GGC03_02595	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GGC03_02600	COG3956	TIGRFAM MazG family protein
GGC03_02610	COG0148	phosphopyruvate hydratase activity
GGC03_02615	COG0617	tRNA 3'-terminal CCA addition
GGC03_02620	COG3409	Peptidoglycan-binding domain 1 protein
GGC03_02620	COG3267	Type II secretory pathway component ExeA
GGC03_02630	COG4991	sh3 domain protein
GGC03_02635	COG0306	phosphate transporter
GGC03_02640	COG1392	Phosphate transport regulator
GGC03_02645	COG3025	triphosphatase activity
GGC03_02650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GGC03_02660	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GGC03_02675	COG0745	RESPONSE REGULATOR receiver
GGC03_02705	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GGC03_02710	COG2860	membrane
GGC03_02715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GGC03_02720	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GGC03_02745	COG1846	Transcriptional regulator
GGC03_02750	COG0534	Mate efflux family protein
GGC03_02755	COG2204	response regulator
GGC03_02770	COG0667	Aldo Keto reductase
GGC03_02780	COG3066	DNA modification
GGC03_02795	COG0730	response to heat
GGC03_02805	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GGC03_02810	COG1283	sodium-dependent phosphate transmembrane transporter activity
GGC03_02815	COG0583	DNA-binding transcription factor activity
GGC03_02820	COG0640	Transcriptional regulator
GGC03_02825	COG0268	Binds directly to 16S ribosomal RNA
GGC03_02830	COG0728	peptidoglycan biosynthetic process
GGC03_02835	COG0196	riboflavin kinase activity
GGC03_02850	COG1047	Peptidyl-prolyl cis-trans
GGC03_02855	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GGC03_02860	COG1966	Carbon starvation protein
GGC03_02870	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GGC03_02875	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GGC03_02880	COG2971	BadF BadG BcrA BcrD
GGC03_02890	COG1737	Transcriptional regulator
GGC03_02895	COG1472	Belongs to the glycosyl hydrolase 3 family
GGC03_02900	COG3279	Response regulator of the LytR AlgR family
GGC03_02905	COG3275	phosphorelay sensor kinase activity
GGC03_02910	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GGC03_02915	COG0287	Prephenate dehydrogenase
GGC03_02915	COG1605	Chorismate mutase
GGC03_02920	COG0739	heme binding
GGC03_02930	COG0488	(ABC) transporter
GGC03_02935	COG0741	lytic transglycosylase activity
GGC03_02940	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GGC03_02945	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GGC03_02950	COG5001	Diguanylate cyclase
GGC03_02955	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GGC03_02960	COG0077	Prephenate dehydratase
GGC03_02960	COG1605	Chorismate mutase
GGC03_02965	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GGC03_02970	COG0741	lytic transglycosylase activity
GGC03_02975	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GGC03_02980	COG0564	pseudouridine synthase activity
GGC03_02990	COG0542	response to heat
GGC03_03030	COG0483	inositol monophosphate 1-phosphatase activity
GGC03_03040	COG1959	2 iron, 2 sulfur cluster binding
GGC03_03050	COG0822	iron-sulfur transferase activity
GGC03_03070	COG0633	Ferredoxin
GGC03_03075	COG2975	iron-sulfur cluster assembly
GGC03_03080	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GGC03_03090	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GGC03_03095	COG0583	DNA-binding transcription factor activity
GGC03_03105	COG0583	DNA-binding transcription factor activity
GGC03_03110	COG1022	Amp-dependent synthetase and ligase
GGC03_03115	COG2169	Transcriptional regulator
GGC03_03145	COG4964	Belongs to the GSP D family
GGC03_03195	COG2169	Transcriptional regulator
GGC03_03200	COG1486	melibiose metabolic process
GGC03_03205	COG2211	Major facilitator Superfamily
GGC03_03215	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GGC03_03215	COG3408	Glycogen debranching enzyme
GGC03_03230	COG1309	transcriptional regulator
GGC03_03235	COG0531	amino acid
GGC03_03240	COG2731	YhcH YjgK YiaL family protein
GGC03_03245	COG3250	beta-galactosidase activity
GGC03_03250	COG1609	Transcriptional regulator
GGC03_03255	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GGC03_03260	COG1085	galactose-1-phosphate uridylyltransferase
GGC03_03270	COG2017	converts alpha-aldose to the beta-anomer
GGC03_03280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GGC03_03290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC03_03290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC03_03290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC03_03295	COG2207	Transcriptional regulator
GGC03_03305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC03_03315	COG2171	N-acyltransferase activity
GGC03_03320	COG0450	alkyl hydroperoxide reductase
GGC03_03325	COG0583	DNA-binding transcription factor activity
GGC03_03330	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GGC03_03355	COG0517	IMP dehydrogenase activity
GGC03_03360	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GGC03_03370	COG1862	Preprotein translocase
GGC03_03375	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GGC03_03380	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GGC03_03395	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
GGC03_03400	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GGC03_03415	COG0745	RESPONSE REGULATOR receiver
GGC03_03420	COG5002	protein histidine kinase activity
GGC03_03430	COG0248	Ppx GppA phosphatase
GGC03_03435	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GGC03_03440	COG0573	inorganic phosphate transmembrane transporter activity
GGC03_03445	COG0581	inorganic phosphate transmembrane transporter activity
GGC03_03450	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GGC03_03455	COG0704	Plays a role in the regulation of phosphate uptake
GGC03_03470	COG3141	response to X-ray
GGC03_03475	COG1309	transcriptional regulator
GGC03_03480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC03_03500	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GGC03_03505	COG1074	ATP-dependent DNA helicase activity
GGC03_03510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GGC03_03530	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GGC03_03535	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GGC03_03540	COG2166	iron-sulfur cluster assembly
GGC03_03550	COG1426	Protein conserved in bacteria
GGC03_03560	COG0124	histidyl-tRNA synthetase
GGC03_03565	COG2976	Protein conserved in bacteria
GGC03_03570	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GGC03_03575	COG1160	GTP binding
GGC03_03585	COG2203	Gaf domain
GGC03_03585	COG2199	diguanylate cyclase activity
GGC03_03600	COG0517	IMP dehydrogenase activity
GGC03_03600	COG0516	GMP reductase activity
GGC03_03615	COG1584	GPR1 FUN34 yaaH family protein
GGC03_03620	COG1115	amino acid carrier protein
GGC03_03630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGC03_03650	COG2873	o-acetylhomoserine
GGC03_03655	COG0784	Response regulator, receiver
GGC03_03655	COG0835	chemotaxis
GGC03_03660	COG0204	Acyl-transferase
GGC03_03680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GGC03_03685	COG0668	transmembrane transport
GGC03_03705	COG2867	negative regulation of translational initiation
GGC03_03715	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GGC03_03720	COG0497	DNA recombination
GGC03_03730	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GGC03_03735	COG1301	dicarboxylic acid transport
GGC03_03740	COG0443	Heat shock 70 kDa protein
GGC03_03755	COG4970	Tfp pilus assembly protein FimT
GGC03_03775	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GGC03_03780	COG0590	tRNA wobble adenosine to inosine editing
GGC03_03790	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GGC03_03795	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GGC03_03795	COG0047	phosphoribosylformylglycinamidine synthase activity
GGC03_03820	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GGC03_03825	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GGC03_03830	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GGC03_03835	COG1187	pseudouridine synthase activity
GGC03_03840	COG2840	Smr protein MutS2
GGC03_03865	COG3104	oligopeptide transport
GGC03_03870	COG0367	asparagine synthase
GGC03_03875	COG4651	solute:proton antiporter activity
GGC03_03875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GGC03_03880	COG1846	Transcriptional regulator
GGC03_03880	COG1940	carbohydrate kinase activity
GGC03_03885	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GGC03_03890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGC03_03890	COG1263	PTS System
GGC03_03890	COG2190	(PTS) system
GGC03_03910	COG0716	FMN binding
GGC03_03920	COG0596	Alpha beta hydrolase
GGC03_03925	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GGC03_03930	COG0033	Phosphoglucomutase
GGC03_03940	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GGC03_03955	COG2009	succinate dehydrogenase
GGC03_03960	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GGC03_03965	COG1053	succinate dehydrogenase
GGC03_03970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GGC03_03975	COG0567	Dehydrogenase, E1 component
GGC03_03980	COG0508	dehydrogenase complex catalyzes the overall conversion of
GGC03_03995	COG1943	Transposase
GGC03_04025	COG3098	single-species biofilm formation
GGC03_04030	COG0564	pseudouridine synthase activity
GGC03_04040	COG0142	geranyltranstransferase activity
GGC03_04050	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GGC03_04060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GGC03_04060	COG0301	tRNA thio-modification
GGC03_04070	COG0583	DNA-binding transcription factor activity
GGC03_04095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GGC03_04100	COG1611	Belongs to the LOG family
GGC03_04105	COG3706	GGDEF domain
GGC03_04105	COG0745	RESPONSE REGULATOR receiver
GGC03_04125	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GGC03_04140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GGC03_04145	COG1393	Belongs to the ArsC family
GGC03_04175	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GGC03_04180	COG0437	4 iron, 4 sulfur cluster binding
GGC03_04185	COG3301	Polysulphide reductase, NrfD
GGC03_04190	COG1138	Cytochrome C-type biogenesis protein
GGC03_04195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GGC03_04200	COG3088	subunit of a heme lyase
GGC03_04200	COG4235	cytochrome complex assembly
GGC03_04210	COG2837	iron assimilation
GGC03_04225	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GGC03_04235	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GGC03_04245	COG1516	flagellar protein fliS
GGC03_04255	COG2204	response regulator
GGC03_04260	COG4191	Histidine kinase
GGC03_04265	COG2204	response regulator
GGC03_04270	COG1677	Flagellar hook-basal body complex protein FliE
GGC03_04280	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GGC03_04330	COG1987	bacterial-type flagellum assembly
GGC03_04335	COG1684	flagellar biosynthetic protein fliR
GGC03_04350	COG2890	protein-(glutamine-N5) methyltransferase activity
GGC03_04355	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GGC03_04365	COG2860	membrane
GGC03_04370	COG3101	peptidyl-lysine hydroxylation
GGC03_04400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GGC03_04405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GGC03_04410	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GGC03_04430	COG0101	tRNA pseudouridine synthase activity
GGC03_04440	COG0285	dihydrofolate synthase activity
GGC03_04445	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GGC03_04450	COG1286	toxin biosynthetic process
GGC03_04455	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GGC03_04460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GGC03_04465	COG1121	(ABC) transporter
GGC03_04470	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GGC03_04475	COG4977	sequence-specific DNA binding
GGC03_04480	COG1918	ferrous iron import across plasma membrane
GGC03_04485	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GGC03_04500	COG0018	arginyl-trna synthetase
GGC03_04505	COG3102	Protein conserved in bacteria
GGC03_04510	COG1025	Belongs to the peptidase M16 family
GGC03_04515	COG2062	phosphohistidine phosphatase, SixA
GGC03_04530	COG0455	bacterial-type flagellum organization
GGC03_04545	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GGC03_04550	COG2198	Histidine kinase
GGC03_04550	COG0643	Histidine kinase
GGC03_04555	COG2201	protein-glutamate methylesterase activity
GGC03_04560	COG1192	Involved in chromosome partitioning
GGC03_04570	COG0835	chemotaxis
GGC03_04580	COG4133	protoheme IX ABC transporter activity
GGC03_04585	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GGC03_04590	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GGC03_04595	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GGC03_04605	COG1138	Cytochrome C-type biogenesis protein
GGC03_04610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GGC03_04615	COG3088	subunit of a heme lyase
GGC03_04615	COG4235	cytochrome complex assembly
GGC03_04625	COG2853	Lipoprotein
GGC03_04630	COG2067	long-chain fatty acid transport protein
GGC03_04635	COG2067	long-chain fatty acid transport protein
GGC03_04650	COG0183	Belongs to the thiolase family
GGC03_04660	COG0778	Nitroreductase
GGC03_04665	COG0583	DNA-binding transcription factor activity
GGC03_04670	COG0745	RESPONSE REGULATOR receiver
GGC03_04685	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GGC03_04695	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GGC03_04735	COG0745	RESPONSE REGULATOR receiver
GGC03_04740	COG2205	protein histidine kinase activity
GGC03_04745	COG1653	transport
GGC03_04760	COG3842	ATPase activity
GGC03_04765	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GGC03_04770	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GGC03_04775	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GGC03_04785	COG2204	response regulator
GGC03_04810	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GGC03_04815	COG0776	regulation of translation
GGC03_04820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GGC03_04825	COG1555	photosystem II stabilization
GGC03_04835	COG0539	negative regulation of cytoplasmic translation
GGC03_04845	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GGC03_04850	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GGC03_04855	COG0284	orotidine-5'-phosphate decarboxylase activity
GGC03_04890	COG4120	Belongs to the binding-protein-dependent transport system permease family
GGC03_04900	COG3706	GGDEF domain
GGC03_04905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GGC03_04925	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GGC03_04930	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GGC03_04940	COG0252	asparaginase activity
GGC03_04945	COG0616	signal peptide processing
GGC03_04950	COG0446	pyridine nucleotide-disulphide oxidoreductase
GGC03_04950	COG1902	pentaerythritol trinitrate reductase activity
GGC03_04955	COG0788	formyltetrahydrofolate deformylase activity
GGC03_04965	COG1199	ATP-dependent helicase activity
GGC03_04970	COG1214	PFAM Peptidase M22, glycoprotease
GGC03_04985	COG2267	carboxylic ester hydrolase activity
GGC03_04990	COG0318	PFAM AMP-dependent synthetase and ligase
GGC03_04995	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GGC03_05000	COG0659	secondary active sulfate transmembrane transporter activity
GGC03_05005	COG1530	ribonuclease E activity
GGC03_05010	COG0564	pseudouridine synthase activity
GGC03_05015	COG0424	maF-like protein
GGC03_05020	COG1399	metal-binding, possibly nucleic acid-binding protein
GGC03_05035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GGC03_05060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GGC03_05065	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GGC03_05070	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GGC03_05075	COG0470	DNA polymerase III
GGC03_05080	COG0084	hydrolase, TatD family'
GGC03_05085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGC03_05085	COG1263	PTS System
GGC03_05095	COG1943	Transposase
GGC03_05105	COG0733	neurotransmitter:sodium symporter activity
GGC03_05120	COG4667	esterase of the alpha-beta hydrolase superfamily
GGC03_05125	COG0469	pyruvate kinase activity
GGC03_05130	COG1940	carbohydrate kinase activity
GGC03_05135	COG0784	Response regulator, receiver
GGC03_05135	COG0835	chemotaxis
GGC03_05155	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_05160	COG0616	signal peptide processing
GGC03_05165	COG0513	Belongs to the DEAD box helicase family
GGC03_05180	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GGC03_05185	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GGC03_05195	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GGC03_05200	COG0436	Aminotransferase
GGC03_05205	COG1169	isochorismate synthase
GGC03_05210	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GGC03_05215	COG0596	Alpha beta hydrolase
GGC03_05225	COG1441	menaquinone biosynthetic process
GGC03_05240	COG2855	membrane
GGC03_05245	COG0477	Major facilitator Superfamily
GGC03_05270	COG1522	sequence-specific DNA binding
GGC03_05285	COG1946	Acyl-CoA thioesterase
GGC03_05290	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GGC03_05305	COG3706	GGDEF domain
GGC03_05355	COG1414	Transcriptional regulator
GGC03_05360	COG0280	phosphate acetyltransferase
GGC03_05365	COG0730	response to heat
GGC03_05385	COG2855	membrane
GGC03_05400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGC03_05405	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GGC03_05410	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GGC03_05430	COG1472	Belongs to the glycosyl hydrolase 3 family
GGC03_05435	COG3876	Protein conserved in bacteria
GGC03_05445	COG1215	transferase activity, transferring glycosyl groups
GGC03_05460	COG3397	chitin binding
GGC03_05465	COG1770	oligopeptidase
GGC03_05475	COG3227	Zinc metalloprotease (Elastase)
GGC03_05485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC03_05510	COG0577	efflux transmembrane transporter activity
GGC03_05510	COG1136	(ABC) transporter
GGC03_05530	COG0330	HflC and HflK could
GGC03_05540	COG0840	transmembrane signaling receptor activity
GGC03_05545	COG1404	Belongs to the peptidase S8 family
GGC03_05570	COG3706	GGDEF domain
GGC03_05575	COG2067	long-chain fatty acid transport protein
GGC03_05590	COG0601	transmembrane transport
GGC03_05595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GGC03_05600	COG0444	Belongs to the ABC transporter superfamily
GGC03_05610	COG0435	Glutathione S-transferase
GGC03_05615	COG3706	GGDEF domain
GGC03_05620	COG0857	belongs to the CobB CobQ family
GGC03_05620	COG0280	phosphate acetyltransferase
GGC03_05630	COG3092	negative regulation of chromosome organization
GGC03_05635	COG0686	Belongs to the AlaDH PNT family
GGC03_05645	COG1674	ftsk spoiiie
GGC03_05660	COG2186	Transcriptional regulator
GGC03_05675	COG0537	adenosine 5'-monophosphoramidase activity
GGC03_05705	COG1252	NADH dehydrogenase
GGC03_05710	COG1943	Transposase
GGC03_05730	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GGC03_05740	COG4591	ABC-type transport system involved in lipoprotein release permease component
GGC03_05745	COG1136	(ABC) transporter
GGC03_05750	COG4591	ABC-type transport system involved in lipoprotein release permease component
GGC03_05760	COG0658	competence protein
GGC03_05760	COG2333	competence protein COMEC
GGC03_05765	COG1132	(ABC) transporter
GGC03_05780	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GGC03_05785	COG2719	SpoVR family
GGC03_05790	COG2718	Belongs to the UPF0229 family
GGC03_05795	COG2766	serine protein kinase
GGC03_05800	COG3713	MltA-interacting MipA family protein
GGC03_05815	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GGC03_05830	COG1882	Formate acetyltransferase
GGC03_05850	COG4215	(ABC) transporter
GGC03_05865	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GGC03_06005	COG3772	lysozyme
GGC03_06020	COG4695	Portal protein
GGC03_06060	COG4386	tail sheath protein
GGC03_06095	COG3646	Phage regulatory protein
GGC03_06125	COG1012	belongs to the aldehyde dehydrogenase family
GGC03_06125	COG1454	alcohol dehydrogenase
GGC03_06130	COG1737	Transcriptional regulator
GGC03_06135	COG0076	glutamate decarboxylase activity
GGC03_06145	COG2431	L-lysine efflux transmembrane transporter activity
GGC03_06155	COG3070	regulator of competence-specific genes
GGC03_06170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC03_06170	COG4191	Histidine kinase
GGC03_06180	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GGC03_06190	COG1032	radical SAM domain protein
GGC03_06210	COG0583	DNA-binding transcription factor activity
GGC03_06215	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GGC03_06220	COG1764	response to oxidative stress
GGC03_06225	COG1846	Transcriptional regulator
GGC03_06235	COG0583	DNA-binding transcription factor activity
GGC03_06245	COG0673	inositol 2-dehydrogenase activity
GGC03_06250	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GGC03_06270	COG0840	transmembrane signaling receptor activity
GGC03_06275	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GGC03_06290	COG3152	Membrane
GGC03_06335	COG1858	cytochrome C peroxidase
GGC03_06350	COG0443	Heat shock 70 kDa protein
GGC03_06400	COG1643	Atp-dependent helicase
GGC03_06410	COG1301	dicarboxylic acid transport
GGC03_06415	COG0159	tryptophan synthase activity
GGC03_06420	COG0133	tryptophan synthase activity
GGC03_06425	COG0134	indole-3-glycerol-phosphate synthase activity
GGC03_06425	COG0135	phosphoribosylanthranilate isomerase activity
GGC03_06430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GGC03_06435	COG0512	Glutamine amidotransferase of anthranilate synthase
GGC03_06440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GGC03_06450	COG0613	PHP domain protein
GGC03_06455	COG0009	L-threonylcarbamoyladenylate synthase
GGC03_06470	COG1187	pseudouridine synthase activity
GGC03_06475	COG0384	phenazine biosynthesis protein PhzF
GGC03_06485	COG2814	Major facilitator Superfamily
GGC03_06490	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GGC03_06495	COG4988	ABC transporter
GGC03_06500	COG0492	ferredoxin-NADP+ reductase activity
GGC03_06515	COG2175	clavaminate synthase activity
GGC03_06530	COG0612	Peptidase, M16
GGC03_06540	COG2949	membrane
GGC03_06550	COG0281	malic enzyme
GGC03_06555	COG1643	Atp-dependent helicase
GGC03_06570	COG1448	Aminotransferase
GGC03_06575	COG2770	Histidine kinase
GGC03_06575	COG3437	response regulator, receiver
GGC03_06585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGC03_06600	COG0017	Asparaginyl-tRNA synthetase
GGC03_06620	COG0814	amino acid
GGC03_06630	COG1760	l-serine dehydratase
GGC03_06635	COG0814	amino acid
GGC03_06640	COG0494	nUDIX hydrolase
GGC03_06650	COG0784	Response regulator, receiver
GGC03_06650	COG2205	protein histidine kinase activity
GGC03_06670	COG3106	COG3106 Predicted ATPase
GGC03_06680	COG3283	Transcriptional regulator of aromatic amino acids metabolism
GGC03_06685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GGC03_06705	COG3706	GGDEF domain
GGC03_06710	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GGC03_06735	COG2989	Protein conserved in bacteria
GGC03_06740	COG3108	Peptidase M15
GGC03_06745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GGC03_06760	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GGC03_06795	COG4667	esterase of the alpha-beta hydrolase superfamily
GGC03_06800	COG0783	Belongs to the Dps family
GGC03_06810	COG0531	amino acid
GGC03_06815	COG2962	Rard protein
GGC03_06875	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GGC03_06990	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GGC03_07025	COG0546	phosphoglycolate phosphatase activity
GGC03_07030	COG4628	conserved protein (DUF2132)
GGC03_07040	COG0456	acetyltransferase
GGC03_07050	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GGC03_07060	COG0730	response to heat
GGC03_07070	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_07080	COG2824	Alkylphosphonate utilization operon protein PhnA
GGC03_07095	COG0456	acetyltransferase
GGC03_07115	COG3040	lipid binding
GGC03_07130	COG3122	Protein conserved in bacteria
GGC03_07190	COG0454	-acetyltransferase
GGC03_07195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GGC03_07220	COG0456	acetyltransferase
GGC03_07240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGC03_07255	COG2195	Cleaves the N-terminal amino acid of tripeptides
GGC03_07265	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GGC03_07275	COG0625	glutathione transferase activity
GGC03_07290	COG2885	chlorophyll binding
GGC03_07305	COG0277	FAD linked oxidase domain protein
GGC03_07305	COG0247	lactate metabolic process
GGC03_07320	COG2986	histidine ammonia-lyase
GGC03_07330	COG0010	Belongs to the arginase family
GGC03_07335	COG1228	amidohydrolase
GGC03_07340	COG2188	Transcriptional regulator
GGC03_07345	COG4326	sporulation control protein
GGC03_07365	COG0500	methyltransferase
GGC03_07385	COG1346	cytolysis
GGC03_07395	COG2925	Exonuclease
GGC03_07405	COG0702	epimerase
GGC03_07410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GGC03_07420	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GGC03_07430	COG0406	alpha-ribazole phosphatase activity
GGC03_07465	COG3706	GGDEF domain
GGC03_07475	COG2814	Major facilitator Superfamily
GGC03_07485	COG1119	ATPase activity
GGC03_07495	COG0784	Response regulator, receiver
GGC03_07495	COG5002	protein histidine kinase activity
GGC03_07505	COG1451	nucleotide metabolic process
GGC03_07520	COG3063	Type IV pilus biogenesis stability protein PilW
GGC03_07525	COG0508	dehydrogenase complex catalyzes the overall conversion of
GGC03_07525	COG0596	Alpha beta hydrolase
GGC03_07545	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GGC03_07560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC03_07585	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GGC03_07590	COG0515	serine threonine protein kinase
GGC03_07690	COG3501	Rhs element vgr protein
GGC03_07705	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GGC03_07710	COG0372	Belongs to the citrate synthase family
GGC03_07720	COG2828	Protein conserved in bacteria
GGC03_07740	COG0561	phosphatase activity
GGC03_07745	COG0602	queuosine metabolic process
GGC03_07780	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GGC03_07785	COG0840	transmembrane signaling receptor activity
GGC03_07790	COG1254	Belongs to the acylphosphatase family
GGC03_07795	COG2920	part of a sulfur-relay system
GGC03_07800	COG0670	Belongs to the BI1 family
GGC03_07805	COG1126	abc transporter atp-binding protein
GGC03_07810	COG0765	amino acid transport
GGC03_07815	COG4597	amino acid ABC transporter
GGC03_07820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC03_07830	COG1666	GTP binding
GGC03_07835	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GGC03_07870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GGC03_07870	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GGC03_07875	COG3008	intermembrane lipid transfer
GGC03_07880	COG2995	paraquat-inducible protein a
GGC03_07885	COG1132	(ABC) transporter
GGC03_07890	COG1956	GAF domain-containing protein
GGC03_07895	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GGC03_07910	COG0308	aminopeptidase N
GGC03_07925	COG0167	dihydroorotate dehydrogenase activity
GGC03_07935	COG0116	Belongs to the methyltransferase superfamily
GGC03_07935	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GGC03_07945	COG0488	(ABC) transporter
GGC03_07960	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GGC03_07965	COG1067	ATP-dependent peptidase activity
GGC03_08020	COG0789	Transcriptional regulator
GGC03_08055	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GGC03_08075	COG0840	transmembrane signaling receptor activity
GGC03_08210	COG3424	synthase
GGC03_08225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GGC03_08250	COG1132	(ABC) transporter
GGC03_08365	COG3278	Belongs to the heme-copper respiratory oxidase family
GGC03_08380	COG2010	Cytochrome c
GGC03_08390	COG2217	Heavy metal translocating P-type atpase
GGC03_08405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GGC03_08410	COG0589	response to stress
GGC03_08435	COG3842	ATPase activity
GGC03_08440	COG1176	ABC-type spermidine putrescine transport system, permease component I
GGC03_08445	COG1177	transmembrane transport
GGC03_08450	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GGC03_08455	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GGC03_08460	COG2199	diguanylate cyclase activity
GGC03_08465	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GGC03_08470	COG0004	ammonium transporteR
GGC03_08485	COG0437	4 iron, 4 sulfur cluster binding
GGC03_08490	COG3383	formate dehydrogenase (NAD+) activity
GGC03_08490	COG0243	molybdopterin cofactor binding
GGC03_08520	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GGC03_08535	COG3038	cytochrome b561
GGC03_08560	COG0583	DNA-binding transcription factor activity
GGC03_08570	COG0583	DNA-binding transcription factor activity
GGC03_08575	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GGC03_08595	COG0069	glutamate synthase activity
GGC03_08600	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_08615	COG0488	(ABC) transporter
GGC03_08625	COG1595	DNA-templated transcription, initiation
GGC03_08640	COG3852	Histidine kinase
GGC03_08655	COG4662	Binding-protein-dependent transport system inner membrane component
GGC03_08660	COG3842	ATPase activity
GGC03_08665	COG0746	molybdenum cofactor guanylyltransferase activity
GGC03_08670	COG0303	'Molybdopterin
GGC03_08700	COG1940	carbohydrate kinase activity
GGC03_08715	COG0840	transmembrane signaling receptor activity
GGC03_08720	COG0791	NLP P60 protein
GGC03_08740	COG0307	riboflavin synthase, alpha
GGC03_08790	COG2204	response regulator
GGC03_08800	COG0438	transferase activity, transferring glycosyl groups
GGC03_08835	COG0297	glycogen (starch) synthase activity
GGC03_08845	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GGC03_08885	COG4774	siderophore transport
GGC03_08905	COG4615	Cyclic peptide transporter
GGC03_08915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GGC03_08920	COG1120	ATPase activity
GGC03_08925	COG2977	Belongs to the P-Pant transferase superfamily
GGC03_08930	COG1929	Belongs to the glycerate kinase type-1 family
GGC03_08935	COG3835	regulator
GGC03_08945	COG2814	Major facilitator Superfamily
GGC03_08955	COG1288	antiporter activity
GGC03_08965	COG2186	Transcriptional regulator
GGC03_08975	COG3713	MltA-interacting MipA family protein
GGC03_08985	COG0745	RESPONSE REGULATOR receiver
GGC03_08995	COG0583	DNA-binding transcription factor activity
GGC03_09015	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GGC03_09035	COG2116	formate transmembrane transporter activity
GGC03_09040	COG2146	nitrite reductase [NAD(P)H] activity
GGC03_09045	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GGC03_09075	COG4565	transcriptional regulatory protein
GGC03_09080	COG3290	protein histidine kinase activity
GGC03_09100	COG0848	biopolymer transport protein
GGC03_09105	COG0811	peptide transport
GGC03_09110	COG0811	peptide transport
GGC03_09120	COG4774	siderophore transport
GGC03_09130	COG2205	protein histidine kinase activity
GGC03_09135	COG0745	RESPONSE REGULATOR receiver
GGC03_09140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GGC03_09180	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GGC03_09185	COG1328	CTP reductase activity
GGC03_09190	COG0840	transmembrane signaling receptor activity
GGC03_09200	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GGC03_09210	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GGC03_09215	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GGC03_09220	COG0633	Ferredoxin
GGC03_09245	COG0019	diaminopimelate decarboxylase activity
GGC03_09290	COG1136	(ABC) transporter
GGC03_09295	COG0534	Mate efflux family protein
GGC03_09300	COG0702	epimerase
GGC03_09310	COG2814	Major facilitator Superfamily
GGC03_09320	COG1061	Type III restriction enzyme res subunit
GGC03_09335	COG2205	protein histidine kinase activity
GGC03_09360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGC03_09365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC03_09385	COG0463	Glycosyl transferase, family 2
GGC03_09420	COG0455	bacterial-type flagellum organization
GGC03_09435	COG2188	Transcriptional regulator
GGC03_09440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGC03_09440	COG1263	PTS System
GGC03_09445	COG1621	beta-fructofuranosidase activity
GGC03_09455	COG0583	DNA-binding transcription factor activity
GGC03_09460	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GGC03_09490	COG4221	oxidoreductase activity
GGC03_09525	COG0307	riboflavin synthase, alpha
GGC03_09575	COG0242	peptide deformylase activity
GGC03_09580	COG0519	Catalyzes the synthesis of GMP from XMP
GGC03_09595	COG4580	involved in the transport of maltose and maltodextrins
GGC03_09600	COG0778	Nitroreductase
GGC03_09655	COG5001	Diguanylate cyclase
GGC03_09655	COG3300	MHYT domain
GGC03_09685	COG1115	amino acid carrier protein
GGC03_09690	COG1280	lysine exporter protein (LysE YggA)
GGC03_09695	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GGC03_09700	COG0352	thiamine-phosphate diphosphorylase activity
GGC03_09705	COG0583	DNA-binding transcription factor activity
GGC03_09730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GGC03_09740	COG1012	belongs to the aldehyde dehydrogenase family
GGC03_09750	COG0583	DNA-binding transcription factor activity
GGC03_09805	COG1609	Transcriptional regulator
GGC03_09820	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GGC03_09825	COG1609	Transcriptional regulator
GGC03_09835	COG0642	Histidine kinase
GGC03_09840	COG0745	RESPONSE REGULATOR receiver
GGC03_09860	COG1858	cytochrome C peroxidase
GGC03_09875	COG0784	Response regulator, receiver
GGC03_09875	COG2205	protein histidine kinase activity
GGC03_09880	COG0488	(ABC) transporter
GGC03_09885	COG3437	response regulator, receiver
GGC03_09895	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GGC03_09905	COG2223	nitrite transmembrane transporter activity
GGC03_09910	COG1216	Glycosyl transferase, family 2
GGC03_09920	COG0673	inositol 2-dehydrogenase activity
GGC03_09925	COG3718	enzyme involved in inositol metabolism
GGC03_09950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC03_09955	COG0673	inositol 2-dehydrogenase activity
GGC03_09960	COG3962	Belongs to the TPP enzyme family
GGC03_09975	COG2814	Major facilitator Superfamily
GGC03_09975	COG0477	Major facilitator Superfamily
GGC03_09995	COG0183	Belongs to the thiolase family
GGC03_10000	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GGC03_10040	COG3962	Belongs to the TPP enzyme family
GGC03_10045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC03_10055	COG1129	ABC transporter
GGC03_10060	COG4211	Belongs to the binding-protein-dependent transport system permease family
GGC03_10070	COG0277	FAD linked oxidase domain protein
GGC03_10080	COG0583	DNA-binding transcription factor activity
GGC03_10100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC03_10105	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GGC03_10125	COG1621	beta-fructofuranosidase activity
GGC03_10140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGC03_10140	COG1263	PTS System
GGC03_10150	COG1335	isochorismatase
GGC03_10155	COG1741	Belongs to the pirin family
GGC03_10195	COG4974	Belongs to the 'phage' integrase family
GGC03_10205	COG1733	regulation of RNA biosynthetic process
GGC03_10215	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GGC03_10235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GGC03_10240	COG0072	phenylalanine-tRNA ligase activity
GGC03_10240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GGC03_10250	COG3706	GGDEF domain
GGC03_10275	COG2133	pyrroloquinoline quinone binding
GGC03_10285	COG1902	pentaerythritol trinitrate reductase activity
GGC03_10315	COG0322	excinuclease ABC activity
GGC03_10320	COG2197	response regulator
GGC03_10335	COG0417	DNA replication proofreading
GGC03_10350	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GGC03_10355	COG3099	Belongs to the UPF0263 family
GGC03_10390	COG1607	acyl-coa hydrolase
GGC03_10395	COG2350	Protein conserved in bacteria
GGC03_10410	COG3313	Fe-S protein
GGC03_10420	COG4134	Bacterial extracellular solute-binding protein
GGC03_10425	COG4135	transport system, permease component
GGC03_10430	COG4136	ATPase activity
GGC03_10435	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GGC03_10445	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GGC03_10450	COG0564	pseudouridine synthase activity
GGC03_10455	COG0733	neurotransmitter:sodium symporter activity
GGC03_10465	COG0626	cystathionine gamma-synthase activity
GGC03_10470	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GGC03_10475	COG5380	lipid catabolic process
GGC03_10480	COG2818	Glycosylase
GGC03_10495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC03_10500	COG1983	PspC domain protein
GGC03_10510	COG1842	Phage shock protein A
GGC03_10515	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GGC03_10525	COG4168	peptide transport system, permease
GGC03_10530	COG4171	peptide transport system, permease
GGC03_10540	COG4172	Belongs to the ABC transporter superfamily
GGC03_10555	COG1227	inorganic diphosphatase activity
GGC03_10565	COG0217	transcriptional regulatory protein
GGC03_10570	COG0140	phosphoribosyl-ATP diphosphatase activity
GGC03_10570	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GGC03_10575	COG0107	imidazoleglycerol-phosphate synthase activity
GGC03_10580	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GGC03_10585	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GGC03_10590	COG0131	Imidazoleglycerol-phosphate dehydratase
GGC03_10590	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GGC03_10600	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GGC03_10610	COG1757	Na H antiporter
GGC03_10620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC03_10630	COG0482	sulfurtransferase activity
GGC03_10640	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GGC03_10650	COG2268	Band 7 protein
GGC03_10660	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GGC03_10675	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_10695	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GGC03_10700	COG2226	methyltransferase
GGC03_10700	COG1073	alpha beta
GGC03_10705	COG0156	8-amino-7-oxononanoate synthase activity
GGC03_10715	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GGC03_10730	COG1199	ATP-dependent helicase activity
GGC03_10735	COG0730	response to heat
GGC03_10750	COG2850	peptidyl-arginine hydroxylation
GGC03_10755	COG0840	transmembrane signaling receptor activity
GGC03_10760	COG0708	Exodeoxyribonuclease III
GGC03_10765	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GGC03_10770	COG1960	acyl-CoA dehydrogenase activity
GGC03_10790	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GGC03_10795	COG0463	Glycosyl transferase, family 2
GGC03_10800	COG0745	RESPONSE REGULATOR receiver
GGC03_10805	COG3850	Histidine kinase
GGC03_10805	COG5002	protein histidine kinase activity
GGC03_10820	COG1940	carbohydrate kinase activity
GGC03_10835	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GGC03_10840	COG1881	PFAM PEBP family protein
GGC03_10845	COG1902	pentaerythritol trinitrate reductase activity
GGC03_10865	COG0784	Response regulator, receiver
GGC03_10865	COG5002	protein histidine kinase activity
GGC03_10885	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GGC03_10890	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GGC03_10895	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GGC03_10900	COG2885	chlorophyll binding
GGC03_10920	COG0811	peptide transport
GGC03_10925	COG0824	Thioesterase
GGC03_10935	COG4890	Cyd operon protein YbgT
GGC03_10940	COG1294	oxidase, subunit
GGC03_10945	COG1271	oxidase subunit
GGC03_10950	COG2255	four-way junction helicase activity
GGC03_10955	COG0632	four-way junction helicase activity
GGC03_10960	COG0840	transmembrane signaling receptor activity
GGC03_10965	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GGC03_10985	COG4221	oxidoreductase activity
GGC03_11000	COG0243	molybdopterin cofactor binding
GGC03_11005	COG3005	denitrification pathway
GGC03_11010	COG4459	periplasmic nitrate reductase
GGC03_11015	COG0390	transport system, permease component
GGC03_11025	COG2116	formate transmembrane transporter activity
GGC03_11050	COG0542	response to heat
GGC03_11055	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GGC03_11060	COG1278	Cold shock
GGC03_11070	COG1187	pseudouridine synthase activity
GGC03_11080	COG1801	Protein of unknown function DUF72
GGC03_11090	COG0500	methyltransferase
GGC03_11095	COG4067	protein conserved in archaea
GGC03_11095	COG0189	ligase activity
GGC03_11125	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GGC03_11130	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GGC03_11140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GGC03_11145	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GGC03_11150	COG0745	RESPONSE REGULATOR receiver
GGC03_11165	COG3070	regulator of competence-specific genes
GGC03_11190	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GGC03_11195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GGC03_11220	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GGC03_11225	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GGC03_11230	COG1435	thymidine kinase activity
GGC03_11235	COG0215	cysteine-tRNA ligase activity
GGC03_11240	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GGC03_11250	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GGC03_11255	COG3012	SEC-C Motif Domain Protein
GGC03_11260	COG3139	Protein of unknown function (DUF1315)
GGC03_11270	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GGC03_11285	COG0840	transmembrane signaling receptor activity
GGC03_11290	COG2226	methyltransferase
GGC03_11305	COG1785	Belongs to the alkaline phosphatase family
GGC03_11325	COG0668	transmembrane transport
GGC03_11330	COG2983	Belongs to the UPF0260 family
GGC03_11345	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GGC03_11350	COG0583	DNA-binding transcription factor activity
GGC03_11355	COG2951	lytic endotransglycosylase activity
GGC03_11360	COG3100	YcgL domain-containing protein
GGC03_11365	COG0850	regulation of cytokinetic process
GGC03_11370	COG2894	cell division
GGC03_11380	COG1012	belongs to the aldehyde dehydrogenase family
GGC03_11380	COG1454	alcohol dehydrogenase
GGC03_11385	COG2095	MarC family integral membrane protein
GGC03_11390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GGC03_11395	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GGC03_11400	COG1757	Na H antiporter
GGC03_11425	COG3082	Protein of unknown function (DUF1414)
GGC03_11430	COG3083	sulfuric ester hydrolase activity
GGC03_11465	COG3852	Histidine kinase
GGC03_11495	COG0123	including yeast histone deacetylase and acetoin utilization protein
GGC03_11505	COG1881	PFAM PEBP family protein
GGC03_11515	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GGC03_11520	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GGC03_11540	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GGC03_11545	COG0302	gtp cyclohydrolase
GGC03_11545	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GGC03_11550	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GGC03_11555	COG0302	gtp cyclohydrolase
GGC03_11565	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GGC03_11570	COG0110	maltose O-acetyltransferase activity
GGC03_11620	COG2982	Protein involved in outer membrane biogenesis
GGC03_11625	COG0572	uridine kinase
GGC03_11630	COG0489	protein tyrosine kinase activity
GGC03_11675	COG0517	IMP dehydrogenase activity
GGC03_11685	COG3706	GGDEF domain
GGC03_11690	COG0314	molybdopterin synthase activity
GGC03_11695	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GGC03_11700	COG0315	cyclic pyranopterin monophosphate synthase activity
GGC03_11705	COG0521	Mo-molybdopterin cofactor biosynthetic process
GGC03_11710	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GGC03_11715	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GGC03_11720	COG2198	Histidine kinase
GGC03_11735	COG0556	nucleotide-excision repair
GGC03_11750	COG0739	heme binding
GGC03_11775	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GGC03_11790	COG2204	response regulator
GGC03_11795	COG2885	chlorophyll binding
GGC03_11815	COG1987	bacterial-type flagellum assembly
GGC03_11825	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GGC03_11840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GGC03_11845	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GGC03_11850	COG1516	flagellar protein fliS
GGC03_11865	COG1580	Controls the rotational direction of flagella during chemotaxis
GGC03_11870	COG1191	sigma factor activity
GGC03_11875	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GGC03_11880	COG1360	Flagellar Motor Protein
GGC03_11910	COG1706	bacterial-type flagellum-dependent cell motility
GGC03_11915	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GGC03_11920	COG4786	Flagellar basal body rod
GGC03_11925	COG4787	bacterial-type flagellum-dependent cell motility
GGC03_11930	COG1749	Flagellar hook protein flgE
GGC03_11935	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GGC03_11940	COG1558	bacterial-type flagellum-dependent cell motility
GGC03_11945	COG1815	bacterial-type flagellum-dependent cell motility
GGC03_11965	COG1388	LysM domain
GGC03_11965	COG0741	lytic transglycosylase activity
GGC03_11970	COG4657	Part of a membrane complex involved in electron transport
GGC03_11980	COG4656	Part of a membrane complex involved in electron transport
GGC03_11985	COG4658	electron transport chain
GGC03_12000	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GGC03_12005	COG0346	lactoylglutathione lyase activity
GGC03_12025	COG2056	Na+-H+ antiporter family
GGC03_12035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GGC03_12040	COG2716	regulation of RNA biosynthetic process
GGC03_12045	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GGC03_12065	COG4783	chaperone-mediated protein folding
GGC03_12070	COG1393	Belongs to the ArsC family
GGC03_12095	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GGC03_12110	COG2912	Transglutaminase-like superfamily
GGC03_12120	COG2890	protein-(glutamine-N5) methyltransferase activity
GGC03_12145	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GGC03_12155	COG0012	GTP binding
GGC03_12275	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GGC03_12285	COG1705	Flagellar rod assembly protein muramidase FlgJ
GGC03_12285	COG3951	Flagellar rod assembly protein muramidase FlgJ
GGC03_12290	COG1706	bacterial-type flagellum-dependent cell motility
GGC03_12295	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GGC03_12300	COG4786	Flagellar basal body rod
GGC03_12305	COG4787	bacterial-type flagellum-dependent cell motility
GGC03_12310	COG1749	Flagellar hook protein flgE
GGC03_12315	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GGC03_12320	COG1558	bacterial-type flagellum-dependent cell motility
GGC03_12325	COG1815	bacterial-type flagellum-dependent cell motility
GGC03_12330	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GGC03_12335	COG0784	Response regulator, receiver
GGC03_12335	COG0835	chemotaxis
GGC03_12345	COG2747	anti-sigma28 factor FlgM
GGC03_12385	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GGC03_12395	COG2194	sulfuric ester hydrolase activity
GGC03_12415	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GGC03_12415	COG2885	chlorophyll binding
GGC03_12435	COG2608	mercury ion transmembrane transporter activity
GGC03_12435	COG2217	Heavy metal translocating P-type atpase
GGC03_12455	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GGC03_12465	COG0326	Molecular chaperone. Has ATPase activity
GGC03_12470	COG3710	Transcriptional regulator
GGC03_12490	COG0622	Phosphoesterase
GGC03_12515	COG1090	epimerase
GGC03_12520	COG0300	oxidoreductase activity
GGC03_12525	COG3118	belongs to the thioredoxin family
GGC03_12530	COG0330	HflC and HflK could
GGC03_12560	COG3115	cell septum assembly
GGC03_12565	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GGC03_12570	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GGC03_12575	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC03_12585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GGC03_12590	COG2190	(PTS) system
GGC03_12595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GGC03_12605	COG1702	phosphate starvation-inducible protein PhoH
GGC03_12610	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GGC03_12615	COG4535	Mg2 and Co2 transporter CorC
GGC03_12620	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GGC03_12625	COG2888	peptidyl-tyrosine sulfation
GGC03_12630	COG0495	leucyl-tRNA aminoacylation
GGC03_12635	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GGC03_12640	COG1466	dna polymerase III delta subunit
GGC03_12645	COG0799	negative regulation of ribosome biogenesis
GGC03_12650	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GGC03_12655	COG0768	penicillin binding
GGC03_12660	COG0772	Belongs to the SEDS family
GGC03_12665	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GGC03_12670	COG1686	Belongs to the peptidase S11 family
GGC03_12685	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GGC03_12700	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GGC03_12710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGC03_12715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC03_12725	COG0366	Alpha amylase catalytic
GGC03_12730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGC03_12730	COG1263	PTS System
GGC03_12735	COG1609	Transcriptional regulator
GGC03_12745	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GGC03_12750	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GGC03_12755	COG2011	ABC-type metal ion transport system permease component
GGC03_12760	COG1464	Belongs to the NlpA lipoprotein family
GGC03_12775	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GGC03_12785	COG1720	tRNA m6t6A37 methyltransferase activity
GGC03_12795	COG0121	glutamine amidotransferase
GGC03_12800	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GGC03_12805	COG1960	acyl-CoA dehydrogenase activity
GGC03_12815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GGC03_12825	COG2226	methyltransferase
GGC03_12835	COG0741	lytic transglycosylase activity
GGC03_12835	COG1388	LysM domain
GGC03_12850	COG0347	Belongs to the P(II) protein family
GGC03_12865	COG0825	malonyl-CoA metabolic process
GGC03_12870	COG0587	DNA-directed DNA polymerase activity
GGC03_12875	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GGC03_12895	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GGC03_12900	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GGC03_12905	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GGC03_12910	COG0750	zinc metalloprotease
GGC03_12920	COG0575	Belongs to the CDS family
GGC03_12925	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GGC03_12930	COG0233	cytoplasmic translational termination
GGC03_12935	COG0528	UMP kinase activity
GGC03_12945	COG0052	Belongs to the universal ribosomal protein uS2 family
GGC03_12955	COG0024	Methionine aminopeptidase
GGC03_12970	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GGC03_12975	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GGC03_13000	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GGC03_13000	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GGC03_13005	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GGC03_13010	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GGC03_13015	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GGC03_13030	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GGC03_13035	COG2252	PERMEase
GGC03_13040	COG2195	Cleaves the N-terminal amino acid of tripeptides
GGC03_13045	COG4067	protein conserved in archaea
GGC03_13045	COG0189	ligase activity
GGC03_13050	COG0189	ligase activity
GGC03_13060	COG0733	neurotransmitter:sodium symporter activity
GGC03_13075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GGC03_13085	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GGC03_13090	COG3706	GGDEF domain
GGC03_13090	COG0745	RESPONSE REGULATOR receiver
GGC03_13100	COG1477	protein flavinylation
GGC03_13105	COG2871	sodium ion transport
GGC03_13110	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GGC03_13125	COG1805	sodium ion transport
GGC03_13130	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GGC03_13135	COG0271	Belongs to the BolA IbaG family
GGC03_13140	COG2813	Specifically methylates the guanine in position
GGC03_13150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GGC03_13165	COG1595	DNA-templated transcription, initiation
GGC03_13180	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GGC03_13185	COG0693	protein deglycase activity
GGC03_13190	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GGC03_13195	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GGC03_13205	COG0560	Phosphoserine phosphatase
GGC03_13215	COG0813	purine-nucleoside phosphorylase activity
GGC03_13220	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GGC03_13225	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GGC03_13240	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GGC03_13245	COG0084	hydrolase, TatD family'
GGC03_13255	COG3022	response to hydroperoxide
GGC03_13260	COG1115	amino acid carrier protein
GGC03_13295	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GGC03_13325	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GGC03_13330	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GGC03_13340	COG0583	DNA-binding transcription factor activity
GGC03_13345	COG0730	response to heat
GGC03_13350	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GGC03_13355	COG0505	Belongs to the CarA family
GGC03_13365	COG0494	nUDIX hydrolase
GGC03_13370	COG0653	protein targeting
GGC03_13375	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GGC03_13380	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GGC03_13385	COG0849	cell division
GGC03_13390	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GGC03_13405	COG0772	Belongs to the SEDS family
GGC03_13410	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GGC03_13415	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GGC03_13420	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GGC03_13430	COG0768	penicillin binding
GGC03_13435	COG3116	cell division
GGC03_13455	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GGC03_13460	COG3107	peptidoglycan biosynthetic process
GGC03_13470	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GGC03_13480	COG2969	positive regulation of protein catabolic process
GGC03_13485	COG0625	glutathione transferase activity
GGC03_13490	COG2857	Cytochrome c1
GGC03_13495	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GGC03_13500	COG0723	plastoquinol--plastocyanin reductase activity
GGC03_13515	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GGC03_13520	COG3105	Protein conserved in bacteria
GGC03_13525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GGC03_13530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GGC03_13540	COG0187	DNA topoisomerase II activity
GGC03_13545	COG3150	esterase
GGC03_13555	COG3151	Protein conserved in bacteria
GGC03_13560	COG0494	nUDIX hydrolase
GGC03_13565	COG1538	Outer membrane efflux protein
GGC03_13575	COG5002	protein histidine kinase activity
GGC03_13575	COG2198	Histidine kinase
GGC03_13575	COG0784	Response regulator, receiver
GGC03_13580	COG4251	negative regulation of phosphorylation
GGC03_13580	COG5001	Diguanylate cyclase
GGC03_13580	COG3706	GGDEF domain
GGC03_13580	COG2203	Gaf domain
GGC03_13585	COG1242	4 iron, 4 sulfur cluster binding
GGC03_13590	COG0069	glutamate synthase activity
GGC03_13590	COG0070	glutamate synthase
GGC03_13590	COG0067	glutamate synthase
GGC03_13600	COG0067	glutamate synthase
GGC03_13600	COG0069	glutamate synthase activity
GGC03_13600	COG0070	glutamate synthase
GGC03_13605	COG0493	'glutamate synthase
GGC03_13630	COG0195	Participates in both transcription termination and antitermination
GGC03_13635	COG0779	Required for maturation of 30S ribosomal subunits
GGC03_13650	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GGC03_13655	COG3153	acetyltransferase
GGC03_13680	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GGC03_13685	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GGC03_13700	COG0513	Belongs to the DEAD box helicase family
GGC03_13730	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GGC03_13735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GGC03_13740	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GGC03_13745	COG1534	Rna-binding protein
GGC03_13750	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GGC03_13755	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GGC03_13760	COG2027	D-alanyl-D-alanine carboxypeptidase
GGC03_13770	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GGC03_13775	COG0739	heme binding
GGC03_13800	COG0628	permease
GGC03_13805	COG2813	Specifically methylates the guanine in position
GGC03_13815	COG0747	negative chemotaxis
GGC03_13830	COG0444	Belongs to the ABC transporter superfamily
GGC03_13835	COG4608	Belongs to the ABC transporter superfamily
GGC03_13845	COG2971	BadF BadG BcrA BcrD
GGC03_13860	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GGC03_13865	COG3842	ATPase activity
GGC03_13875	COG1840	ABC-type Fe3 transport system, periplasmic component
GGC03_13880	COG0004	ammonium transporteR
GGC03_13895	COG1049	propionate catabolic process, 2-methylcitrate cycle
GGC03_13900	COG1752	Esterase of the alpha-beta hydrolase superfamily
GGC03_13905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GGC03_13910	COG1643	Atp-dependent helicase
GGC03_13920	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GGC03_13935	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GGC03_13950	COG0842	Transport permease protein
GGC03_13955	COG1131	(ABC) transporter
GGC03_13960	COG0659	secondary active sulfate transmembrane transporter activity
GGC03_13965	COG0288	reversible hydration of carbon dioxide
GGC03_13980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GGC03_13985	COG0508	dehydrogenase complex catalyzes the overall conversion of
GGC03_13990	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GGC03_13995	COG2186	Transcriptional regulator
GGC03_14000	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GGC03_14005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GGC03_14015	COG0716	FMN binding
GGC03_14020	COG3023	N-Acetylmuramoyl-L-alanine amidase
GGC03_14025	COG0157	Belongs to the NadC ModD family
GGC03_14030	COG4969	Belongs to the N-Me-Phe pilin family
GGC03_14035	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GGC03_14040	COG1459	type II secretion system
GGC03_14050	COG0237	dephospho-CoA kinase activity
GGC03_14055	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GGC03_14060	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GGC03_14070	COG0336	Belongs to the RNA methyltransferase TrmD family
GGC03_14080	COG0228	four-way junction DNA binding
GGC03_14085	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GGC03_14090	COG4137	Cytochrome C assembly protein
GGC03_14095	COG4536	flavin adenine dinucleotide binding
GGC03_14100	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GGC03_14105	COG4942	peptidase
GGC03_14105	COG1388	LysM domain
GGC03_14115	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GGC03_14120	COG0585	pseudouridine synthase activity
GGC03_14130	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GGC03_14135	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GGC03_14145	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GGC03_14150	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GGC03_14155	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GGC03_14160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GGC03_14165	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GGC03_14170	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GGC03_14175	COG1610	YqeY-like protein
GGC03_14180	COG0358	DNA primase activity
GGC03_14185	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GGC03_14195	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GGC03_14200	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GGC03_14205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GGC03_14210	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GGC03_14225	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GGC03_14235	COG3610	response to peptide
GGC03_14240	COG2966	Psort location CytoplasmicMembrane, score
GGC03_14245	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GGC03_14250	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GGC03_14255	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GGC03_14260	COG0142	geranyltranstransferase activity
GGC03_14270	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GGC03_14280	COG2213	PTS system mannitol-specific
GGC03_14280	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC03_14290	COG3722	fumarate hydratase activity
GGC03_14295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGC03_14300	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GGC03_14305	COG1349	DNA-binding transcription factor activity
GGC03_14310	COG0469	pyruvate kinase activity
GGC03_14320	COG3706	GGDEF domain
GGC03_14330	COG0583	DNA-binding transcription factor activity
GGC03_14345	COG0668	transmembrane transport
GGC03_14350	COG0191	fructose-bisphosphate aldolase activity
GGC03_14365	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GGC03_14370	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GGC03_14380	COG3091	SprT-like family
GGC03_14385	COG2356	endonuclease I
GGC03_14390	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GGC03_14395	COG0189	ligase activity
GGC03_14405	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GGC03_14420	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GGC03_14425	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GGC03_14430	COG0762	integral membrane protein
GGC03_14580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GGC03_14585	COG2066	Belongs to the glutaminase family
GGC03_14590	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GGC03_14600	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GGC03_14655	COG0312	modulator of DNA gyrase
GGC03_14660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GGC03_14665	COG3164	Protein of unknown function
GGC03_14670	COG1530	ribonuclease E activity
GGC03_14675	COG0424	maF-like protein
GGC03_14680	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GGC03_14685	COG1792	Involved in formation and maintenance of cell shape
GGC03_14690	COG1077	Cell shape determining protein MreB Mrl
GGC03_14735	COG1459	type II secretion system
GGC03_14740	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GGC03_14750	COG3267	Type II secretory pathway component ExeA
GGC03_14750	COG3409	Peptidoglycan-binding domain 1 protein
GGC03_14775	COG2200	EAL domain
GGC03_14775	COG2199	diguanylate cyclase activity
GGC03_14780	COG0629	single-stranded DNA binding
GGC03_14795	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GGC03_14805	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GGC03_14810	COG0527	aspartate kinase activity
GGC03_14815	COG0312	modulator of DNA gyrase
GGC03_14820	COG3028	Belongs to the UPF0307 family
GGC03_14825	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GGC03_14830	COG1178	ABC-type Fe3 transport system permease component
GGC03_14835	COG4143	(ABC) transporter
GGC03_14840	COG0163	prenyltransferase activity
GGC03_14845	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GGC03_14860	COG2105	PFAM AIG2 family protein
GGC03_14865	COG2911	Protein conserved in bacteria
GGC03_14870	COG0729	surface antigen
GGC03_14875	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GGC03_14885	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GGC03_14895	COG1136	(ABC) transporter
GGC03_14925	COG0432	Pfam Uncharacterised protein family UPF0047
GGC03_15020	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GGC03_15025	COG0305	Participates in initiation and elongation during chromosome replication
GGC03_15045	COG0360	Binds together with S18 to 16S ribosomal RNA
GGC03_15055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GGC03_15060	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GGC03_15065	COG0049	tRNA binding
GGC03_15075	COG2168	tRNA wobble position uridine thiolation
GGC03_15080	COG2923	Belongs to the DsrF TusC family
GGC03_15090	COG2964	Protein conserved in bacteria
GGC03_15095	COG0545	Peptidyl-prolyl cis-trans isomerase
GGC03_15110	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GGC03_15115	COG0330	HflC and HflK could
GGC03_15120	COG0330	HflC and HflK could
GGC03_15125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GGC03_15140	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GGC03_15150	COG0802	atpase or kinase
GGC03_15155	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GGC03_15200	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GGC03_15205	COG1162	GTPase activity
GGC03_15210	COG0688	phosphatidylethanolamine metabolic process
GGC03_15215	COG0490	domain, Protein
GGC03_15215	COG0471	metal ion transport
GGC03_15220	COG0840	transmembrane signaling receptor activity
GGC03_15230	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GGC03_15235	COG4942	peptidase
GGC03_15255	COG2816	NAD+ diphosphatase activity
GGC03_15260	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GGC03_15270	COG0085	RNA polymerase activity
GGC03_15280	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GGC03_15295	COG0250	Participates in transcription elongation, termination and antitermination
GGC03_15300	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GGC03_15310	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GGC03_15335	COG1072	(Pantothenic acid kinase))
GGC03_15350	COG0149	triose-phosphate isomerase activity
GGC03_15355	COG0534	Mate efflux family protein
GGC03_15360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GGC03_15365	COG1575	Belongs to the MenA family. Type 1 subfamily
GGC03_15370	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GGC03_15375	COG1509	lysine 2,3-aminomutase activity
GGC03_15385	COG1285	pathogenesis
GGC03_15390	COG0205	6-phosphofructokinase activity
GGC03_15400	COG3678	ATP-independent chaperone mediated protein folding
GGC03_15405	COG0745	RESPONSE REGULATOR receiver
GGC03_15410	COG2205	protein histidine kinase activity
GGC03_15415	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GGC03_15420	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GGC03_15425	COG0180	Tryptophanyl-tRNA synthetase
GGC03_15430	COG0546	phosphoglycolate phosphatase activity
GGC03_15435	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GGC03_15440	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GGC03_15485	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GGC03_15495	COG0678	peroxiredoxin activity
GGC03_15495	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GGC03_15505	COG0251	oxidation-reduction process
GGC03_15510	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GGC03_15510	COG0165	Argininosuccinate lyase
GGC03_15515	COG0137	argininosuccinate synthase activity
GGC03_15525	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GGC03_15625	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GGC03_15635	COG4206	TonB-dependent receptor
GGC03_15660	COG0534	Mate efflux family protein
GGC03_15670	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GGC03_15675	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GGC03_15685	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GGC03_15690	COG3161	chorismate lyase activity
GGC03_15695	COG1580	Controls the rotational direction of flagella during chemotaxis
GGC03_15705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GGC03_15710	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GGC03_15715	COG2177	Part of the ABC transporter FtsEX involved in
GGC03_15720	COG2884	Cell division ATP-binding protein ftsE
GGC03_15725	COG0552	protein localization to endoplasmic reticulum
GGC03_15730	COG0742	ribosomal rna small subunit methyltransferase
GGC03_15740	COG2095	MarC family integral membrane protein
GGC03_15785	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GGC03_15790	COG0640	Transcriptional regulator
GGC03_15795	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GGC03_15800	COG1280	lysine exporter protein (LysE YggA)
GGC03_15810	COG0561	phosphatase activity
GGC03_15830	COG2199	diguanylate cyclase activity
GGC03_15830	COG3287	FIST C domain
GGC03_15830	COG2200	EAL domain
GGC03_15835	COG1011	Hydrolase
GGC03_15840	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GGC03_15850	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GGC03_15855	COG0019	diaminopimelate decarboxylase activity
GGC03_15860	COG1965	Belongs to the frataxin family
GGC03_15865	COG3072	Adenylate cyclase
GGC03_15875	COG1587	Uroporphyrinogen-III synthase
GGC03_15880	COG2959	enzyme of heme biosynthesis
GGC03_15885	COG3071	HemY protein
GGC03_15945	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GGC03_15955	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GGC03_15960	COG3118	belongs to the thioredoxin family
GGC03_15970	COG0248	Ppx GppA phosphatase
GGC03_15975	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GGC03_15985	COG0514	ATP-dependent DNA helicase (RecQ)
GGC03_15990	COG2962	Rard protein
GGC03_16000	COG1280	lysine exporter protein (LysE YggA)
GGC03_16005	COG0405	Gamma-glutamyltransferase
GGC03_16025	COG0210	DNA helicase
GGC03_16040	COG3220	belongs to the UPF0276 family
GGC03_16060	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GGC03_16065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GGC03_16080	COG1773	rubredoxin
GGC03_16095	COG0367	asparagine synthase
GGC03_16100	COG0477	Major facilitator Superfamily
GGC03_16125	COG0745	RESPONSE REGULATOR receiver
GGC03_16140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GGC03_16150	COG0747	negative chemotaxis
GGC03_16195	COG1309	transcriptional regulator
GGC03_16200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC03_16205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGC03_16210	COG2960	long-chain fatty acid transporting porin activity
GGC03_16220	COG0583	DNA-binding transcription factor activity
GGC03_16225	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GGC03_16250	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GGC03_16260	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GGC03_16260	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GGC03_16275	COG1943	Transposase
GGC03_16285	COG0084	hydrolase, TatD family'
GGC03_16290	COG0805	protein transport
GGC03_16320	COG1322	Protein conserved in bacteria
GGC03_16330	COG1639	'signal transduction protein
GGC03_16360	COG2081	HI0933 family
GGC03_16370	COG1528	Iron-storage protein
GGC03_16375	COG0589	response to stress
GGC03_16380	COG0697	spore germination
GGC03_16390	COG0742	ribosomal rna small subunit methyltransferase
GGC03_16395	COG5001	Diguanylate cyclase
GGC03_16395	COG5002	protein histidine kinase activity
GGC03_16400	COG1522	sequence-specific DNA binding
GGC03_16405	COG1943	Transposase
GGC03_16425	COG0006	proline dipeptidase activity
GGC03_16425	COG0006	proline dipeptidase activity
GGC03_16435	COG2022	thiamine diphosphate biosynthetic process
GGC03_16445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GGC03_16450	COG0352	thiamine-phosphate diphosphorylase activity
GGC03_16465	COG2132	Multicopper oxidase
GGC03_16520	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GGC03_16525	COG1739	Uncharacterized protein family UPF0029
GGC03_16535	COG0183	Belongs to the thiolase family
GGC03_16540	COG3706	GGDEF domain
GGC03_16545	COG0583	DNA-binding transcription factor activity
GGC03_16550	COG2814	Major facilitator Superfamily
GGC03_16560	COG0765	amino acid transport
GGC03_16570	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GGC03_16575	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GGC03_16580	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GGC03_16585	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GGC03_16590	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GGC03_16610	COG3312	ion transport
GGC03_16615	COG1475	DNA binding
GGC03_16620	COG1192	Involved in chromosome partitioning
GGC03_16630	COG0445	tRNA wobble uridine modification
GGC03_16635	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GGC03_16640	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GGC03_16645	COG0706	membrane insertase activity
GGC03_16660	COG1126	abc transporter atp-binding protein
GGC03_16680	COG0697	spore germination
GGC03_16700	COG0415	Belongs to the DNA photolyase family
GGC03_16710	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GGC03_16740	COG0840	transmembrane signaling receptor activity
GGC03_16770	COG0840	transmembrane signaling receptor activity
GGC03_16780	COG4580	involved in the transport of maltose and maltodextrins
GGC03_16795	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GGC03_16805	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GGC03_16830	COG0583	DNA-binding transcription factor activity
GGC03_16840	COG1132	(ABC) transporter
GGC03_16845	COG0589	response to stress
GGC03_16855	COG2111	Na H antiporter
GGC03_16855	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GGC03_16860	COG1006	Multisubunit Na H antiporter MnhC subunit
GGC03_16875	COG2212	antiporter activity
GGC03_16880	COG1320	monovalent cation:proton antiporter activity
GGC03_16885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC03_16885	COG4191	Histidine kinase
GGC03_16915	COG0488	(ABC) transporter
GGC03_16920	COG0673	inositol 2-dehydrogenase activity
GGC03_16925	COG5553	Cysteine dioxygenase type I
GGC03_16930	COG0300	oxidoreductase activity
GGC03_16955	COG3047	cAMP biosynthetic process
GGC03_16960	COG0739	heme binding
GGC03_16985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GGC03_16990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGC03_16995	COG0446	pyridine nucleotide-disulphide oxidoreductase
GGC03_17000	COG3383	formate dehydrogenase (NAD+) activity
GGC03_17010	COG0004	ammonium transporteR
GGC03_17040	COG1234	tRNA 3'-trailer cleavage
GGC03_17045	COG0583	DNA-binding transcription factor activity
GGC03_17065	COG3304	Inner membrane component domain
GGC03_17070	COG2329	Antibiotic biosynthesis monooxygenase
GGC03_17080	COG3046	protein related to deoxyribodipyrimidine photolyase
GGC03_17085	COG0415	Belongs to the DNA photolyase family
GGC03_17110	COG3604	Transcriptional regulator
GGC03_17125	COG0583	DNA-binding transcription factor activity
GGC03_17135	COG1151	hydroxylamine reductase activity
GGC03_17140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GGC03_17145	COG0583	DNA-binding transcription factor activity
GGC03_17190	COG0745	RESPONSE REGULATOR receiver
GGC03_17210	COG1288	antiporter activity
GGC03_17215	COG3608	succinylglutamate desuccinylase aspartoacylase
GGC03_17245	COG1522	sequence-specific DNA binding
GGC03_17255	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GGC03_17260	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GGC03_17265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GGC03_17295	COG0840	transmembrane signaling receptor activity
GGC03_17300	COG0454	-acetyltransferase
GGC03_17315	COG0363	glucosamine-6-phosphate deaminase activity
GGC03_17320	COG4720	Psort location CytoplasmicMembrane, score
GGC03_17325	COG1122	ATPase activity
GGC03_17345	COG1162	GTPase activity
GGC03_17350	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GGC03_17370	COG0581	inorganic phosphate transmembrane transporter activity
GGC03_17375	COG0573	inorganic phosphate transmembrane transporter activity
GGC03_17380	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GGC03_17385	COG0840	transmembrane signaling receptor activity
GGC03_17395	COG4221	oxidoreductase activity
GGC03_17415	COG1477	protein flavinylation
GGC03_17470	COG2894	cell division
GGC03_17480	COG4964	Belongs to the GSP D family
GGC03_17515	COG2095	MarC family integral membrane protein
GGC03_17535	COG4176	ABC-type proline glycine betaine transport system permease component
GGC03_17540	COG3448	diguanylate cyclase activity
GGC03_17540	COG4175	Glycine betaine
GGC03_17590	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GGC03_17590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GGC03_17605	COG0590	tRNA wobble adenosine to inosine editing
GGC03_17610	COG2076	Multidrug Resistance protein
GGC03_17615	COG2076	Multidrug Resistance protein
GGC03_17620	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GGC03_17625	COG1960	acyl-CoA dehydrogenase activity
GGC03_17630	COG0662	Cupin 2, conserved barrel domain protein
GGC03_17640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GGC03_17650	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GGC03_17675	COG4264	IucA IucC family
GGC03_17690	COG1120	ATPase activity
GGC03_17695	COG2814	Major facilitator Superfamily
GGC03_17705	COG4968	Prepilin-type N-terminal cleavage methylation domain
GGC03_17710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC03_17710	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC03_17710	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC03_17720	COG0383	alpha-mannosidase activity
GGC03_17725	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC03_17725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC03_17725	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GGC03_17750	COG0583	DNA-binding transcription factor activity
GGC03_17760	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_17765	COG1414	Transcriptional regulator
GGC03_17790	COG0702	epimerase
GGC03_17840	COG1733	regulation of RNA biosynthetic process
GGC03_17860	COG1917	Cupin 2, conserved barrel domain protein
GGC03_17860	COG4977	sequence-specific DNA binding
GGC03_17865	COG4771	TonB-dependent receptor
GGC03_17870	COG2814	Major facilitator Superfamily
GGC03_17875	COG3433	isochorismatase activity
GGC03_17875	COG2226	methyltransferase
GGC03_17875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GGC03_17890	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GGC03_17895	COG1169	isochorismate synthase
GGC03_17900	COG1021	2,3-dihydroxybenzoate-AMP ligase
GGC03_17905	COG1132	(ABC) transporter
GGC03_17910	COG1132	(ABC) transporter
GGC03_17935	COG0024	Methionine aminopeptidase
GGC03_17950	COG0561	phosphatase activity
GGC03_18000	COG0300	oxidoreductase activity
GGC03_18010	COG0583	DNA-binding transcription factor activity
GGC03_18020	COG2249	NAD(P)H dehydrogenase (quinone) activity
GGC03_18070	COG1619	proteins homologs of microcin C7 resistance protein MccF
GGC03_18085	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GGC03_18090	COG1640	4-alpha-glucanotransferase
GGC03_18095	COG0058	SHG alpha-glucan phosphorylase activity
GGC03_18100	COG2909	trisaccharide binding
GGC03_18145	COG2207	Transcriptional regulator
GGC03_18150	COG1335	isochorismatase
GGC03_18155	COG1404	Belongs to the peptidase S8 family
GGC03_18160	COG0402	S-adenosylhomocysteine deaminase activity
GGC03_18190	COG3795	YCII-related domain
GGC03_18215	COG2186	Transcriptional regulator
GGC03_18225	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GGC03_18235	COG0402	S-adenosylhomocysteine deaminase activity
GGC03_18240	COG2226	methyltransferase
GGC03_18245	COG0784	Response regulator, receiver
GGC03_18245	COG2205	protein histidine kinase activity
GGC03_18245	COG5002	protein histidine kinase activity
GGC03_18255	COG1522	sequence-specific DNA binding
GGC03_18265	COG0840	transmembrane signaling receptor activity
GGC03_18285	COG4266	Belongs to the allantoicase family
GGC03_18305	COG2252	PERMEase
GGC03_18320	COG0596	Alpha beta hydrolase
GGC03_18325	COG3214	Protein conserved in bacteria
GGC03_18350	COG0583	DNA-binding transcription factor activity
GGC03_18375	COG3179	chitinase
GGC03_18390	COG0109	protoheme IX farnesyltransferase activity
GGC03_18395	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GGC03_18400	COG1845	cytochrome c oxidase, subunit III
GGC03_18405	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GGC03_18410	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GGC03_18420	COG2706	6-phosphogluconolactonase activity
GGC03_18430	COG0800	Aldolase
GGC03_18435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC03_18440	COG4145	pantothenate transmembrane transporter activity
GGC03_18450	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GGC03_18465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC03_18470	COG0840	transmembrane signaling receptor activity
GGC03_18515	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GGC03_18520	COG0804	urea catabolic process
GGC03_18525	COG0832	Belongs to the urease beta subunit family
GGC03_18530	COG0831	urea catabolic process
GGC03_18555	COG0559	Belongs to the binding-protein-dependent transport system permease family
GGC03_18570	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GGC03_18590	COG2084	Dehydrogenase
GGC03_18595	COG3622	Belongs to the hyi family
GGC03_18600	COG3960	tartronate-semialdehyde synthase activity
GGC03_18605	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GGC03_18615	COG0583	DNA-binding transcription factor activity
GGC03_18620	COG1288	antiporter activity
GGC03_18650	COG1846	Transcriptional regulator
GGC03_18655	COG0697	spore germination
GGC03_18660	COG5001	Diguanylate cyclase
GGC03_18660	COG3300	MHYT domain
GGC03_18675	COG1051	belongs to the nudix hydrolase family
GGC03_18680	COG0583	DNA-binding transcription factor activity
GGC03_18700	COG1733	regulation of RNA biosynthetic process
GGC03_18705	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_18715	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_18750	COG0444	Belongs to the ABC transporter superfamily
GGC03_18755	COG4608	Belongs to the ABC transporter superfamily
GGC03_18785	COG1444	tRNA N-acetyltransferase activity
GGC03_18790	COG0840	transmembrane signaling receptor activity
GGC03_18800	COG0745	RESPONSE REGULATOR receiver
GGC03_18815	COG0835	chemotaxis
GGC03_18820	COG0840	transmembrane signaling receptor activity
GGC03_18825	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GGC03_18850	COG3706	GGDEF domain
GGC03_18850	COG0745	RESPONSE REGULATOR receiver
GGC03_18870	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GGC03_18930	COG0583	DNA-binding transcription factor activity
GGC03_18935	COG1175	transmembrane transport
GGC03_18955	COG0546	phosphoglycolate phosphatase activity
GGC03_18960	COG3842	ATPase activity
GGC03_18970	COG2723	6-phospho-beta-galactosidase activity
GGC03_18975	COG0768	penicillin binding
GGC03_18980	COG0840	transmembrane signaling receptor activity
GGC03_19005	COG0583	DNA-binding transcription factor activity
GGC03_19025	COG0656	L-ascorbic acid biosynthetic process
GGC03_19030	COG0351	phosphomethylpyrimidine kinase
GGC03_19035	COG1116	anion transmembrane transporter activity
GGC03_19040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GGC03_19045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GGC03_19050	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GGC03_19070	COG3708	Transcriptional regulator
GGC03_19070	COG2207	Transcriptional regulator
GGC03_19080	COG0671	phosphoesterase, PA-phosphatase related
GGC03_19090	COG0438	transferase activity, transferring glycosyl groups
GGC03_19100	COG1940	carbohydrate kinase activity
GGC03_19115	COG1175	transmembrane transport
GGC03_19125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GGC03_19165	COG1063	alcohol dehydrogenase
GGC03_19175	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GGC03_19175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GGC03_19185	COG0251	oxidation-reduction process
GGC03_19190	COG0697	spore germination
GGC03_19205	COG1595	DNA-templated transcription, initiation
GGC03_19245	COG0471	metal ion transport
GGC03_19250	COG2205	protein histidine kinase activity
GGC03_19255	COG0745	RESPONSE REGULATOR receiver
GGC03_19280	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GGC03_19290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC03_19295	COG0745	RESPONSE REGULATOR receiver
GGC03_19300	COG2205	protein histidine kinase activity
GGC03_19300	COG3437	response regulator, receiver
GGC03_19300	COG3850	Histidine kinase
GGC03_19300	COG4999	Histidine kinase
GGC03_19315	COG5002	protein histidine kinase activity
GGC03_19320	COG0745	RESPONSE REGULATOR receiver
GGC03_19330	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GGC03_19345	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GGC03_19350	COG3366	ferrous iron transmembrane transporter activity
GGC03_19355	COG0700	Nucleoside recognition
GGC03_19365	COG2207	Transcriptional regulator
GGC03_19380	COG1404	Belongs to the peptidase S8 family
GGC03_19395	COG1301	dicarboxylic acid transport
GGC03_19555	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GGC03_19580	COG0346	lactoylglutathione lyase activity
GGC03_19590	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GGC03_19600	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GGC03_19635	COG2814	Major facilitator Superfamily
GGC03_19640	COG0583	DNA-binding transcription factor activity
GGC03_19645	COG0393	Putative heavy-metal-binding
GGC03_19650	COG1671	Belongs to the UPF0178 family
GGC03_19665	COG1999	signal sequence binding
GGC03_19675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GGC03_19680	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GGC03_19685	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GGC03_19690	COG3033	Beta-eliminating lyase
GGC03_19720	COG0259	pyridoxamine-phosphate oxidase activity
GGC03_19730	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GGC03_19780	COG1132	(ABC) transporter
GGC03_19790	COG0583	DNA-binding transcription factor activity
GGC03_19805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GGC03_19820	COG0786	glutamate:sodium symporter activity
GGC03_19825	COG1566	PFAM secretion protein HlyD family protein
GGC03_19840	COG3706	GGDEF domain
GGC03_19855	COG0813	purine-nucleoside phosphorylase activity
GGC03_19860	COG3272	Protein of unknown function (DUF1722)
GGC03_19865	COG0789	Transcriptional regulator
GGC03_19870	COG0415	Belongs to the DNA photolyase family
GGC03_19875	COG1388	LysM domain
GGC03_19875	COG1376	ErfK ybiS ycfS ynhG family protein
GGC03_19885	COG0513	Belongs to the DEAD box helicase family
GGC03_19890	COG3291	Pkd domain containing protein
GGC03_19895	COG3568	Endonuclease Exonuclease Phosphatase
GGC03_19930	COG0006	proline dipeptidase activity
GGC03_19945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GGC03_19950	COG0601	transmembrane transport
GGC03_19965	COG2186	Transcriptional regulator
GGC03_19975	COG3938	Belongs to the proline racemase family
GGC03_19990	COG2423	ornithine cyclodeaminase activity
GGC03_19995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GGC03_20000	COG3842	ATPase activity
GGC03_20005	COG1176	ABC-type spermidine putrescine transport system, permease component I
GGC03_20010	COG1177	transmembrane transport
GGC03_20020	COG1280	lysine exporter protein (LysE YggA)
GGC03_20030	COG1846	Transcriptional regulator
GGC03_20080	COG2988	succinylglutamate desuccinylase activity
GGC03_20085	COG0523	cobalamin synthesis protein
GGC03_20095	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GGC03_20150	COG0583	DNA-binding transcription factor activity
GGC03_20155	COG1280	lysine exporter protein (LysE YggA)
GGC03_20195	COG1253	flavin adenine dinucleotide binding
GGC03_20230	COG0583	DNA-binding transcription factor activity
GGC03_20235	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GGC03_20240	COG1686	Belongs to the peptidase S11 family
GGC03_20245	COG2814	Major facilitator Superfamily
GGC03_20255	COG1741	Belongs to the pirin family
GGC03_20270	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGC03_20295	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GGC03_20335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GGC03_20340	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GGC03_20345	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GGC03_20350	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GGC03_20375	COG1612	heme a metabolic process
GGC03_20380	COG0109	protoheme IX farnesyltransferase activity
GGC03_20385	COG0765	amino acid transport
GGC03_20390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC03_20395	COG0765	amino acid transport
GGC03_20400	COG1126	abc transporter atp-binding protein
GGC03_20405	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GGC03_20415	COG0366	Alpha amylase catalytic
GGC03_20425	COG4989	oxidoreductase activity
GGC03_20430	COG5001	Diguanylate cyclase
GGC03_20430	COG4251	negative regulation of phosphorylation
GGC03_20430	COG3706	GGDEF domain
GGC03_20430	COG2203	Gaf domain
GGC03_20440	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GGC03_20445	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GGC03_20450	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GGC03_20455	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GGC03_20460	COG0438	transferase activity, transferring glycosyl groups
GGC03_20475	COG1045	serine acetyltransferase
GGC03_20485	COG0438	transferase activity, transferring glycosyl groups
GGC03_20485	COG0297	glycogen (starch) synthase activity
GGC03_20495	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GGC03_20545	COG5001	Diguanylate cyclase
GGC03_20550	COG0583	DNA-binding transcription factor activity
GGC03_20555	COG2814	Major facilitator Superfamily
GGC03_20570	COG0697	spore germination
GGC03_20580	COG0534	Mate efflux family protein
GGC03_20590	COG2249	NAD(P)H dehydrogenase (quinone) activity
GGC03_20595	COG0546	phosphoglycolate phosphatase activity
GGC03_20605	COG3604	Transcriptional regulator
GGC03_20610	COG1017	nitric oxide dioxygenase activity
GGC03_20610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GGC03_20625	COG1278	Cold shock
GGC03_20630	COG3036	rescue of stalled ribosome
GGC03_20645	COG1686	Belongs to the peptidase S11 family
GGC03_20660	COG3530	Putative quorum-sensing-regulated virulence factor
GGC03_20680	COG1012	belongs to the aldehyde dehydrogenase family
GGC03_20695	COG1136	(ABC) transporter
GGC03_20715	COG3275	phosphorelay sensor kinase activity
GGC03_20720	COG3279	Response regulator of the LytR AlgR family
GGC03_20750	COG0366	Alpha amylase catalytic
GGC03_20770	COG0747	negative chemotaxis
GGC03_20775	COG4608	Belongs to the ABC transporter superfamily
GGC03_20780	COG0444	Belongs to the ABC transporter superfamily
GGC03_20785	COG0534	Mate efflux family protein
GGC03_20815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GGC03_20830	COG2130	NADP-dependent
GGC03_20845	COG0745	RESPONSE REGULATOR receiver
GGC03_20850	COG0642	Histidine kinase
GGC03_20875	COG5001	Diguanylate cyclase
GGC03_20880	COG1396	sequence-specific DNA binding
GGC03_20885	COG4948	Mandelate Racemase Muconate Lactonizing
GGC03_20895	COG0583	DNA-binding transcription factor activity
GGC03_20900	COG0443	Heat shock 70 kDa protein
GGC03_20935	COG1280	lysine exporter protein (LysE YggA)
GGC03_20950	COG4232	protein-disulfide reductase activity
GGC03_20955	COG3118	belongs to the thioredoxin family
GGC03_20995	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GGC03_21015	COG0668	transmembrane transport
GGC03_21025	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GGC03_21045	COG0583	DNA-binding transcription factor activity
GGC03_21070	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GGC03_21080	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GGC03_21085	COG3265	gluconokinase activity
GGC03_21090	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GGC03_21095	COG1609	Transcriptional regulator
GGC03_21120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GGC03_21125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GGC03_21130	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GGC03_21135	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GGC03_21165	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GGC03_21170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GGC03_21190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGC03_21215	COG0004	ammonium transporteR
GGC03_21235	COG3469	chitinase activity
GGC03_21245	COG1869	D-ribose catabolic process
GGC03_21250	COG1129	ABC transporter
GGC03_21255	COG1172	Belongs to the binding-protein-dependent transport system permease family
GGC03_21260	COG1879	ABC-type sugar transport system periplasmic component
GGC03_21265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC03_21270	COG1609	Transcriptional regulator
GGC03_21275	COG3437	response regulator, receiver
GGC03_21275	COG0784	Response regulator, receiver
GGC03_21280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC03_21280	COG4191	Histidine kinase
GGC03_21290	COG0513	Belongs to the DEAD box helicase family
GGC03_21300	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GGC03_21310	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GGC03_21325	COG0739	heme binding
GGC03_21335	COG2814	Major facilitator Superfamily
GGC03_21340	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GGC03_21345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GGC03_21355	COG0848	biopolymer transport protein
GGC03_21360	COG0811	peptide transport
GGC03_21365	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GGC03_21375	COG3721	Heme iron utilization protein
GGC03_21380	COG0748	coenzyme F420 binding
GGC03_21385	COG2096	Adenosyltransferase
GGC03_21390	COG3842	ATPase activity
GGC03_21400	COG1175	transmembrane transport
GGC03_21415	COG1943	Transposase
GGC03_21430	COG4533	DNA binding
GGC03_21470	COG2205	protein histidine kinase activity
GGC03_21470	COG5002	protein histidine kinase activity
GGC03_21470	COG0784	Response regulator, receiver
GGC03_21485	COG0861	Integral membrane protein TerC family
GGC03_21490	COG0402	S-adenosylhomocysteine deaminase activity
GGC03_21495	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GGC03_21505	COG1566	PFAM secretion protein HlyD family protein
GGC03_21530	COG0745	RESPONSE REGULATOR receiver
GGC03_21535	COG2205	protein histidine kinase activity
GGC03_21555	COG0531	amino acid
GGC03_21575	COG0673	inositol 2-dehydrogenase activity
GGC03_21580	COG1765	OsmC-like protein
GGC03_21585	COG0110	maltose O-acetyltransferase activity
GGC03_21610	COG2304	oxidoreductase activity
GGC03_21615	COG2304	oxidoreductase activity
GGC03_21630	COG0714	Associated with various cellular activities
GGC03_21645	COG0583	DNA-binding transcription factor activity
GGC03_21650	COG0667	Aldo Keto reductase
GGC03_21665	COG2205	protein histidine kinase activity
GGC03_21670	COG0745	RESPONSE REGULATOR receiver
GGC03_21685	COG0745	RESPONSE REGULATOR receiver
GGC03_21690	COG2205	protein histidine kinase activity
GGC03_21695	COG4452	Inner membrane protein CreD
GGC03_21705	COG0346	lactoylglutathione lyase activity
GGC03_21730	COG2199	diguanylate cyclase activity
GGC03_21730	COG2200	EAL domain
GGC03_21730	COG2202	Pas domain
GGC03_21735	COG0156	8-amino-7-oxononanoate synthase activity
GGC03_21740	COG1063	alcohol dehydrogenase
GGC03_21770	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GGC03_21800	COG0798	PFAM Bile acid sodium symporter
GGC03_21810	COG0612	Peptidase, M16
GGC03_21815	COG2205	protein histidine kinase activity
GGC03_21815	COG0784	Response regulator, receiver
GGC03_21820	COG2205	protein histidine kinase activity
GGC03_21820	COG0784	Response regulator, receiver
GGC03_21840	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GGC03_21845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GGC03_21850	COG3186	Phenylalanine-4-hydroxylase
GGC03_21895	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GGC03_21900	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GGC03_21945	COG1454	alcohol dehydrogenase
GGC03_21950	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GGC03_21965	COG1011	Hydrolase
GGC03_21970	COG2378	regulation of single-species biofilm formation
GGC03_21995	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GGC03_22000	COG1840	ABC-type Fe3 transport system, periplasmic component
GGC03_22010	COG3842	ATPase activity
GGC03_22040	COG2866	Carboxypeptidase
GGC03_22045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGC03_22050	COG0583	DNA-binding transcription factor activity
GGC03_22055	COG1760	l-serine dehydratase
GGC03_22080	COG3706	GGDEF domain
GGC03_22085	COG0784	Response regulator, receiver
GGC03_22085	COG0835	chemotaxis
GGC03_22090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GGC03_22105	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_22115	COG0494	nUDIX hydrolase
GGC03_22120	COG0714	Associated with various cellular activities
GGC03_22125	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GGC03_22130	COG2814	Major facilitator Superfamily
GGC03_22150	COG3706	GGDEF domain
GGC03_22155	COG1846	Transcriptional regulator
GGC03_22160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GGC03_22165	COG2176	DNA-directed DNA polymerase activity
GGC03_22175	COG0789	Transcriptional regulator
GGC03_22185	COG3300	MHYT domain
GGC03_22185	COG5001	Diguanylate cyclase
GGC03_22190	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GGC03_22195	COG0583	DNA-binding transcription factor activity
GGC03_22220	COG1858	cytochrome C peroxidase
GGC03_22240	COG5001	Diguanylate cyclase
GGC03_22240	COG1716	ATPase activity
GGC03_22260	COG2910	NAD(P)H-binding
GGC03_22265	COG0583	DNA-binding transcription factor activity
GGC03_22270	COG1115	amino acid carrier protein
GGC03_22285	COG1741	Belongs to the pirin family
GGC03_22290	COG2259	Doxx family
GGC03_22325	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GGC03_22330	COG1960	acyl-CoA dehydrogenase activity
GGC03_22340	COG0183	Belongs to the thiolase family
GGC03_22350	COG1960	acyl-CoA dehydrogenase activity
GGC03_22355	COG1024	Enoyl-CoA hydratase
GGC03_22360	COG1024	Enoyl-CoA hydratase
GGC03_22370	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_22375	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
GGC03_22395	COG3706	GGDEF domain
GGC03_22420	COG2199	diguanylate cyclase activity
GGC03_22420	COG2203	Gaf domain
GGC03_22430	COG2315	Protein conserved in bacteria
GGC03_22470	COG0243	molybdopterin cofactor binding
GGC03_22475	COG1648	precorrin-2 dehydrogenase activity
GGC03_22475	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GGC03_22480	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GGC03_22490	COG1116	anion transmembrane transporter activity
GGC03_22490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GGC03_22495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GGC03_22500	COG1116	anion transmembrane transporter activity
GGC03_22505	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GGC03_22505	COG2146	nitrite reductase [NAD(P)H] activity
GGC03_22510	COG2146	nitrite reductase [NAD(P)H] activity
GGC03_22535	COG3118	belongs to the thioredoxin family
GGC03_22540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GGC03_22550	COG0419	ATPase involved in DNA repair
GGC03_22555	COG0784	Response regulator, receiver
GGC03_22555	COG2205	protein histidine kinase activity
GGC03_22560	COG0156	8-amino-7-oxononanoate synthase activity
GGC03_22570	COG0038	chloride channel
GGC03_22575	COG0523	cobalamin synthesis protein
GGC03_22590	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GGC03_22610	COG2199	diguanylate cyclase activity
GGC03_22625	COG1522	sequence-specific DNA binding
GGC03_22635	COG1473	amidohydrolase
GGC03_22640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GGC03_22645	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GGC03_22650	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GGC03_22655	COG0006	proline dipeptidase activity
GGC03_22665	COG1522	sequence-specific DNA binding
GGC03_22670	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GGC03_22675	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GGC03_22700	COG2897	thiosulfate sulfurtransferase activity
GGC03_22710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GGC03_22725	COG0513	Belongs to the DEAD box helicase family
GGC03_22735	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GGC03_22735	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GGC03_22740	COG0814	amino acid
GGC03_22755	COG0513	Belongs to the DEAD box helicase family
GGC03_22785	COG1214	PFAM Peptidase M22, glycoprotease
GGC03_22785	COG0456	acetyltransferase
GGC03_22800	COG0346	lactoylglutathione lyase activity
GGC03_22810	COG3048	D-serine ammonia-lyase activity
GGC03_22815	COG0583	DNA-binding transcription factor activity
GGC03_22825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGC03_22830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC03_22845	COG0546	phosphoglycolate phosphatase activity
GGC03_22855	COG0800	Aldolase
GGC03_22860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC03_22865	COG1263	PTS System
GGC03_22865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGC03_22875	COG2188	Transcriptional regulator
GGC03_22880	COG1803	Methylglyoxal synthase
GGC03_22885	COG1879	ABC-type sugar transport system periplasmic component
GGC03_22890	COG2198	Histidine kinase
GGC03_22890	COG2205	protein histidine kinase activity
GGC03_22890	COG0784	Response regulator, receiver
GGC03_22905	COG1979	alcohol dehydrogenase
GGC03_22910	COG2207	Transcriptional regulator
GGC03_22915	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GGC03_22920	COG3706	GGDEF domain
GGC03_22925	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GGC03_22925	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC03_22925	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC03_22930	COG1105	Belongs to the carbohydrate kinase PfkB family
GGC03_22935	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC03_22935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC03_22940	COG1609	Transcriptional regulator
GGC03_22960	COG0725	ABC transporter, periplasmic molybdate-binding protein
GGC03_22965	COG4149	molybdate abc transporter
GGC03_22970	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GGC03_22980	COG5001	Diguanylate cyclase
GGC03_22980	COG4251	negative regulation of phosphorylation
GGC03_22980	COG3706	GGDEF domain
GGC03_22980	COG2203	Gaf domain
GGC03_22985	COG3706	GGDEF domain
GGC03_23000	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GGC03_23005	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GGC03_23015	COG0745	RESPONSE REGULATOR receiver
GGC03_23045	COG0023	Translation Initiation Factor
GGC03_23065	COG1181	Belongs to the D-alanine--D-alanine ligase family
GGC03_23070	COG3266	domain, Protein
GGC03_23075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GGC03_23075	COG1042	CoA-binding domain protein
GGC03_23075	COG0045	succinate-CoA ligase (ADP-forming) activity
GGC03_23080	COG0583	DNA-binding transcription factor activity
GGC03_23085	COG1629	transport
GGC03_23085	COG4771	TonB-dependent receptor
GGC03_23095	COG4533	DNA binding
GGC03_23105	COG2050	protein possibly involved in aromatic compounds catabolism
GGC03_23110	COG4783	chaperone-mediated protein folding
GGC03_23125	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GGC03_23130	COG3070	regulator of competence-specific genes
GGC03_23135	COG0840	transmembrane signaling receptor activity
GGC03_23140	COG2205	protein histidine kinase activity
GGC03_23140	COG0784	Response regulator, receiver
GGC03_23145	COG0745	RESPONSE REGULATOR receiver
GGC03_23160	COG1605	Chorismate mutase
GGC03_23195	COG0737	Belongs to the 5'-nucleotidase family
GGC03_23200	COG3593	DNA synthesis involved in DNA repair
GGC03_23210	COG0583	DNA-binding transcription factor activity
GGC03_23215	COG2116	formate transmembrane transporter activity
GGC03_23220	COG2353	YceI-like domain
GGC03_23225	COG3038	cytochrome b561
GGC03_23245	COG3069	C4-dicarboxylate transmembrane transporter activity
GGC03_23250	COG2197	response regulator
GGC03_23255	COG3850	Histidine kinase
GGC03_23260	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GGC03_23270	COG0243	molybdopterin cofactor binding
GGC03_23280	COG3005	denitrification pathway
GGC03_23290	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GGC03_23295	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GGC03_23305	COG1984	allophanate hydrolase subunit 2
GGC03_23310	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GGC03_23315	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GGC03_23320	COG4181	ATPase activity
GGC03_23330	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GGC03_23335	COG5001	Diguanylate cyclase
GGC03_23335	COG3300	MHYT domain
GGC03_23345	COG0484	heat shock protein binding
GGC03_23365	COG0210	DNA helicase
GGC03_23370	COG1289	transmembrane transporter activity
GGC03_23400	COG5002	protein histidine kinase activity
GGC03_23400	COG0784	Response regulator, receiver
GGC03_23415	COG2827	Endonuclease containing a URI domain
GGC03_23440	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GGC03_23445	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GGC03_23450	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GGC03_23455	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
GGC03_23460	COG0247	lactate metabolic process
GGC03_23480	COG0545	Peptidyl-prolyl cis-trans isomerase
GGC03_23490	COG0189	ligase activity
GGC03_23490	COG4067	protein conserved in archaea
GGC03_23500	COG0602	queuosine metabolic process
GGC03_23505	COG1328	CTP reductase activity
GGC03_23550	COG4412	M6 family metalloprotease domain protein
GGC03_23550	COG3291	Pkd domain containing protein
GGC03_23555	COG3240	lipase activity
GGC03_23560	COG2814	Major facilitator Superfamily
GGC03_23565	COG1794	racemase activity, acting on amino acids and derivatives
GGC03_23580	COG0183	Belongs to the thiolase family
GGC03_23595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC03_23600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC03_23605	COG1309	transcriptional regulator
GGC03_23610	COG1609	Transcriptional regulator
GGC03_23625	COG2211	Major facilitator Superfamily
GGC03_23630	COG3250	beta-galactosidase activity
GGC03_23670	COG1522	sequence-specific DNA binding
GGC03_23705	COG0515	serine threonine protein kinase
GGC03_23705	COG2815	serine threonine protein kinase
GGC03_23730	COG3501	Rhs element vgr protein
GGC03_23770	COG0739	heme binding
GGC03_23780	COG2199	diguanylate cyclase activity
GGC03_23780	COG2203	Gaf domain
GGC03_23785	COG0840	transmembrane signaling receptor activity
GGC03_23795	COG2271	Major facilitator Superfamily
GGC03_23815	COG4206	TonB-dependent receptor
GGC03_23825	COG0004	ammonium transporteR
GGC03_23840	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GGC03_23845	COG4604	ABC transporter, ATP-binding protein
GGC03_23850	COG4605	iron ion homeostasis
GGC03_23855	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GGC03_23895	COG3706	GGDEF domain
GGC03_23895	COG0745	RESPONSE REGULATOR receiver
GGC03_23905	COG4172	Belongs to the ABC transporter superfamily
GGC03_23910	COG4239	(ABC) transporter, permease
GGC03_23915	COG4174	ABC transporter (Permease)
GGC03_23920	COG4166	transmembrane transport
GGC03_23935	COG0840	transmembrane signaling receptor activity
GGC03_23940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GGC03_23945	COG1067	ATP-dependent peptidase activity
GGC03_23955	COG4172	Belongs to the ABC transporter superfamily
GGC03_23960	COG0583	DNA-binding transcription factor activity
GGC03_23965	COG1620	l-lactate permease
GGC03_23970	COG1304	FMN binding
GGC03_23990	COG3448	diguanylate cyclase activity
GGC03_23990	COG4175	Glycine betaine
GGC03_24015	COG1309	transcriptional regulator
GGC03_24030	COG1404	Belongs to the peptidase S8 family
GGC03_24035	COG1346	cytolysis
GGC03_24045	COG0516	GMP reductase activity
GGC03_24050	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GGC03_24050	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GGC03_24065	COG3437	response regulator, receiver
GGC03_24070	COG4999	Histidine kinase
GGC03_24070	COG3437	response regulator, receiver
GGC03_24070	COG3850	Histidine kinase
GGC03_24070	COG2205	protein histidine kinase activity
GGC03_24080	COG2172	sigma factor antagonist activity
GGC03_24090	COG1366	Belongs to the anti-sigma-factor antagonist family
GGC03_24095	COG0840	transmembrane signaling receptor activity
GGC03_24110	COG1943	Transposase
GGC03_24135	COG0366	Alpha amylase catalytic
GGC03_24145	COG2354	Protein conserved in bacteria
GGC03_24170	COG1349	DNA-binding transcription factor activity
GGC03_24180	COG3217	Mosc domain protein beta barrel domain protein
GGC03_24180	COG3217	Mosc domain protein beta barrel domain protein
GGC03_24180	COG0633	Ferredoxin
GGC03_24180	COG0633	Ferredoxin
GGC03_24205	COG2197	response regulator
GGC03_24210	COG3851	Histidine kinase
GGC03_24215	COG2271	Major facilitator Superfamily
GGC03_24225	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GGC03_24235	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GGC03_24240	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GGC03_24245	COG0363	glucosamine-6-phosphate deaminase activity
GGC03_24250	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GGC03_24275	COG3284	Transcriptional regulator
GGC03_24280	COG1012	belongs to the aldehyde dehydrogenase family
GGC03_24310	COG0579	oxidoreductase
GGC03_24320	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GGC03_24330	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GGC03_24335	COG0840	transmembrane signaling receptor activity
GGC03_24360	COG2814	Major facilitator Superfamily
GGC03_24365	COG0583	DNA-binding transcription factor activity
GGC03_24390	COG0564	pseudouridine synthase activity
GGC03_24405	COG2356	endonuclease I
GGC03_24420	COG0251	oxidation-reduction process
GGC03_24460	COG0110	maltose O-acetyltransferase activity
GGC03_24470	COG1621	beta-fructofuranosidase activity
GGC03_24485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGC03_24490	COG1554	hydrolase, family 65, central catalytic
GGC03_24495	COG0395	ABC-type sugar transport system, permease component
GGC03_24515	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GGC03_24525	COG0573	inorganic phosphate transmembrane transporter activity
GGC03_24565	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GGC03_24575	COG0513	Belongs to the DEAD box helicase family
GGC03_24595	COG3706	GGDEF domain
GGC03_24600	COG1309	transcriptional regulator
GGC03_24605	COG2130	NADP-dependent
GGC03_24620	COG2084	Dehydrogenase
GGC03_24640	COG0366	Alpha amylase catalytic
GGC03_24650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGC03_24655	COG0625	glutathione transferase activity
GGC03_24660	COG0346	lactoylglutathione lyase activity
GGC03_24700	COG1131	(ABC) transporter
GGC03_24705	COG0842	Transport permease protein
GGC03_24740	COG5002	protein histidine kinase activity
GGC03_24745	COG0745	RESPONSE REGULATOR receiver
GGC03_24765	COG1309	transcriptional regulator
GGC03_24775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGC03_24800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GGC03_24820	COG1805	sodium ion transport
GGC03_24825	COG1271	oxidase subunit
GGC03_24830	COG1294	oxidase, subunit
GGC03_24835	COG1357	PFAM Pentapeptide repeats (8 copies)
GGC03_24860	COG1522	sequence-specific DNA binding
GGC03_24870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGC03_24890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGC03_24895	COG2207	Transcriptional regulator
GGC03_24895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GGC03_24905	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GGC03_24905	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GGC03_24930	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_24940	COG2274	protein secretion by the type I secretion system
GGC03_24950	COG2274	protein secretion by the type I secretion system
GGC03_24960	COG0583	DNA-binding transcription factor activity
GGC03_24990	COG1280	lysine exporter protein (LysE YggA)
GGC03_24995	COG1917	Cupin 2, conserved barrel domain protein
GGC03_24995	COG2207	Transcriptional regulator
GGC03_25010	COG0625	glutathione transferase activity
GGC03_25015	COG0583	DNA-binding transcription factor activity
GGC03_25040	COG1917	Cupin 2, conserved barrel domain protein
GGC03_25040	COG2207	Transcriptional regulator
GGC03_25050	COG4608	Belongs to the ABC transporter superfamily
GGC03_25055	COG0444	Belongs to the ABC transporter superfamily
GGC03_25060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GGC03_25080	COG1609	Transcriptional regulator
GGC03_25090	COG4580	involved in the transport of maltose and maltodextrins
GGC03_25120	COG0071	Belongs to the small heat shock protein (HSP20) family
GGC03_25125	COG0459	protein refolding
GGC03_25170	COG1917	Cupin 2, conserved barrel domain protein
GGC03_25170	COG2169	Transcriptional regulator
GGC03_25230	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GGC03_25240	COG1335	isochorismatase
GGC03_25245	COG2169	Transcriptional regulator
GGC03_25275	COG2267	carboxylic ester hydrolase activity
GGC03_25310	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GGC03_25320	COG4251	negative regulation of phosphorylation
GGC03_25320	COG3706	GGDEF domain
GGC03_25320	COG5001	Diguanylate cyclase
GGC03_25320	COG2203	Gaf domain
GGC03_25325	COG3706	GGDEF domain
GGC03_25325	COG0745	RESPONSE REGULATOR receiver
GGC03_25360	COG2003	Belongs to the UPF0758 family
GGC03_25465	COG0305	Participates in initiation and elongation during chromosome replication
GGC03_25470	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GGC03_25620	COG4771	TonB-dependent receptor
GGC03_25630	COG4974	Belongs to the 'phage' integrase family
GGC03_25640	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_25645	COG0583	DNA-binding transcription factor activity
GGC03_25685	COG2026	Addiction module toxin, RelE StbE family
GGC03_25740	COG1609	Transcriptional regulator
GGC03_25750	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GGC03_25760	COG1280	lysine exporter protein (LysE YggA)
GGC03_25770	COG0735	belongs to the Fur family
GGC03_25875	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GGC03_25875	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GGC03_25885	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GGC03_25905	COG1181	Belongs to the D-alanine--D-alanine ligase family
GGC03_25910	COG4191	Histidine kinase
GGC03_25980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GGC03_25995	COG1192	Involved in chromosome partitioning
GGC03_26005	COG2814	Major facilitator Superfamily
GGC03_26020	COG3033	Beta-eliminating lyase
GGC03_26050	COG0745	RESPONSE REGULATOR receiver
GGC03_26060	COG4191	Histidine kinase
GGC03_26065	COG5001	Diguanylate cyclase
GGC03_26065	COG3300	MHYT domain
GGC03_26080	COG4191	Histidine kinase
GGC03_26080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC03_26135	COG1309	transcriptional regulator
GGC03_26150	COG1360	Flagellar Motor Protein
GGC03_26175	COG0702	epimerase
GGC03_26200	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
GGC03_26210	COG1879	ABC-type sugar transport system periplasmic component
GGC03_26225	COG3706	GGDEF domain
GGC03_26225	COG2203	Gaf domain
GGC03_26225	COG5001	Diguanylate cyclase
GGC03_26225	COG4251	negative regulation of phosphorylation
GGC03_26240	COG0431	NADPH-dependent FMN reductase
GGC03_26245	COG0583	DNA-binding transcription factor activity
GGC03_26250	COG0583	DNA-binding transcription factor activity
GGC03_26270	COG0840	transmembrane signaling receptor activity
GGC03_26285	COG2203	Gaf domain
GGC03_26285	COG5001	Diguanylate cyclase
GGC03_26285	COG3706	GGDEF domain
GGC03_26285	COG4251	negative regulation of phosphorylation
GGC03_26295	COG0745	RESPONSE REGULATOR receiver
GGC03_26305	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_26310	COG0583	DNA-binding transcription factor activity
GGC03_26320	COG3527	Alpha-acetolactate decarboxylase
GGC03_26330	COG0745	RESPONSE REGULATOR receiver
GGC03_26335	COG2205	protein histidine kinase activity
GGC03_26440	COG0671	phosphoesterase, PA-phosphatase related
GGC03_26455	COG0113	porphobilinogen synthase activity
GGC03_26460	COG0183	Belongs to the thiolase family
GGC03_26470	COG3246	L-lysine catabolic process to acetate
GGC03_26485	COG0604	alcohol dehydrogenase
GGC03_26495	COG0702	epimerase
GGC03_26515	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
GGC03_26530	COG0583	DNA-binding transcription factor activity
GGC03_26535	COG1028	Short-chain dehydrogenase reductase Sdr
GGC03_26635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGC03_26655	COG2084	Dehydrogenase
GGC03_26715	COG4774	siderophore transport
GGC03_26740	COG0494	nUDIX hydrolase
GGC03_26775	COG1742	UPF0060 membrane protein
GGC03_26780	COG0251	oxidation-reduction process
GGC03_26790	COG0583	DNA-binding transcription factor activity
GGC03_26820	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GGC03_26825	COG1051	belongs to the nudix hydrolase family
GGC03_26860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GGC03_26860	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GGC03_26985	COG0629	single-stranded DNA binding
GGC03_27175	COG5301	cellulose 1,4-beta-cellobiosidase activity
GGC03_27210	COG3549	Plasmid maintenance system killer
GGC03_27215	COG3093	addiction module antidote protein HigA
GGC03_27255	COG0860	N-Acetylmuramoyl-L-alanine amidase
GGC03_27255	COG2247	cell wall binding repeat
GGC03_27435	COG1959	2 iron, 2 sulfur cluster binding