locus-tag	class	description
GGC04_00010	COG0592	DNA-directed DNA polymerase activity
GGC04_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GGC04_00020	COG0187	DNA topoisomerase II activity
GGC04_00025	COG0071	Belongs to the small heat shock protein (HSP20) family
GGC04_00030	COG3977	Valine--pyruvate aminotransferase
GGC04_00035	COG0751	glycine-tRNA ligase activity
GGC04_00045	COG2119	membrane
GGC04_00055	COG0425	Belongs to the sulfur carrier protein TusA family
GGC04_00070	COG0604	alcohol dehydrogenase
GGC04_00080	COG0129	dihydroxy-acid dehydratase activity
GGC04_00085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GGC04_00090	COG3978	acetolactate synthase activity
GGC04_00100	COG0606	chelatase, subunit chli
GGC04_00190	COG0606	chelatase, subunit chli
GGC04_00200	COG0204	Acyl-transferase
GGC04_00205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GGC04_00210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GGC04_00220	COG3084	Protein conserved in bacteria
GGC04_00225	COG4326	sporulation control protein
GGC04_00230	COG1272	protein, Hemolysin III
GGC04_00240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GGC04_00245	COG0569	domain protein
GGC04_00250	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GGC04_00250	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GGC04_00260	COG0242	peptide deformylase activity
GGC04_00265	COG0758	DNA mediated transformation
GGC04_00270	COG2922	Belongs to the Smg family
GGC04_00275	COG0551	DNA topoisomerase type I activity
GGC04_00280	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GGC04_00285	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GGC04_00295	COG0408	coproporphyrinogen oxidase activity
GGC04_00310	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GGC04_00350	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GGC04_00360	COG2204	response regulator
GGC04_00365	COG3852	Histidine kinase
GGC04_00370	COG0174	glutamine synthetase
GGC04_00390	COG1490	D-aminoacyl-tRNA deacylase activity
GGC04_00395	COG0456	acetyltransferase
GGC04_00405	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GGC04_00415	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GGC04_00420	COG3031	protein transport across the cell outer membrane
GGC04_00430	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GGC04_00435	COG1459	type II secretion system
GGC04_00440	COG2165	general secretion pathway protein
GGC04_00445	COG2165	general secretion pathway protein
GGC04_00450	COG2165	general secretion pathway protein
GGC04_00455	COG4795	General secretion pathway protein
GGC04_00460	COG3156	type II secretion system protein K
GGC04_00465	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GGC04_00470	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GGC04_00485	COG0745	RESPONSE REGULATOR receiver
GGC04_00490	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GGC04_00500	COG2183	response to ionizing radiation
GGC04_00510	COG0596	Alpha beta hydrolase
GGC04_00520	COG0316	Belongs to the HesB IscA family
GGC04_00520	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GGC04_00525	COG0494	nUDIX hydrolase
GGC04_00530	COG1218	3'(2'),5'-bisphosphate nucleotidase
GGC04_00535	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GGC04_00540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GGC04_00545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GGC04_00560	COG1595	DNA-templated transcription, initiation
GGC04_00590	COG0848	biopolymer transport protein
GGC04_00600	COG2252	PERMEase
GGC04_00605	COG2831	hemolysin activation secretion protein
GGC04_00610	COG3210	domain, Protein
GGC04_00625	COG1561	YicC-like family, N-terminal region
GGC04_00635	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GGC04_00640	COG1560	Kdo2-lipid A biosynthetic process
GGC04_00645	COG1560	Kdo2-lipid A biosynthetic process
GGC04_00650	COG1309	transcriptional regulator
GGC04_00655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GGC04_00660	COG2003	Belongs to the UPF0758 family
GGC04_00690	COG0859	PFAM glycosyl transferase family 9
GGC04_00695	COG0463	Glycosyl transferase, family 2
GGC04_00700	COG0859	PFAM glycosyl transferase family 9
GGC04_00705	COG3642	lipopolysaccharide core region biosynthetic process
GGC04_00720	COG1519	Transferase
GGC04_00735	COG0859	PFAM glycosyl transferase family 9
GGC04_00765	COG1086	Polysaccharide biosynthesis protein
GGC04_00770	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GGC04_00780	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
GGC04_00785	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GGC04_00795	COG2089	acid synthase
GGC04_00805	COG0318	PFAM AMP-dependent synthetase and ligase
GGC04_00815	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GGC04_00830	COG4310	Domain of unknown function (DUF2172)
GGC04_00840	COG2226	methyltransferase
GGC04_00875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GGC04_00880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GGC04_00885	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GGC04_00885	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GGC04_00890	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GGC04_00920	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GGC04_00930	COG1494	fructose-1,6-bisphosphatase
GGC04_00940	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GGC04_00945	COG0527	aspartate kinase activity
GGC04_00945	COG0460	homoserine dehydrogenase
GGC04_00950	COG0626	cystathionine gamma-synthase activity
GGC04_00960	COG0281	malic enzyme
GGC04_00970	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GGC04_00975	COG1609	Transcriptional regulator
GGC04_00980	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GGC04_01010	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GGC04_01015	COG1053	succinate dehydrogenase
GGC04_01020	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GGC04_01025	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GGC04_01060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GGC04_01075	COG1045	serine acetyltransferase
GGC04_01080	COG1695	Transcriptional regulator
GGC04_01085	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GGC04_01090	COG1573	uracil-dna glycosylase
GGC04_01095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GGC04_01100	COG3068	Protein conserved in bacteria
GGC04_01105	COG1253	flavin adenine dinucleotide binding
GGC04_01120	COG0151	Belongs to the GarS family
GGC04_01130	COG0789	Transcriptional regulator
GGC04_01135	COG3706	GGDEF domain
GGC04_01140	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GGC04_01145	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GGC04_01150	COG2264	protein methyltransferase activity
GGC04_01155	COG0439	Biotin carboxylase
GGC04_01160	COG0511	ligase activity, forming carbon-carbon bonds
GGC04_01165	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GGC04_01170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GGC04_01185	COG2814	Major facilitator Superfamily
GGC04_01190	COG2205	protein histidine kinase activity
GGC04_01190	COG0784	Response regulator, receiver
GGC04_01200	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GGC04_01210	COG2095	MarC family integral membrane protein
GGC04_01220	COG4232	protein-disulfide reductase activity
GGC04_01225	COG1438	arginine binding
GGC04_01230	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GGC04_01235	COG0540	Belongs to the ATCase OTCase family
GGC04_01245	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GGC04_01260	COG1288	antiporter activity
GGC04_01265	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GGC04_01270	COG1027	Aspartate ammonia-lyase
GGC04_01355	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GGC04_01375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GGC04_01380	COG3954	Phosphoribulokinase
GGC04_01390	COG0429	hydrolase of the alpha beta-hydrolase fold
GGC04_01400	COG0488	(ABC) transporter
GGC04_01420	COG1047	Peptidyl-prolyl cis-trans
GGC04_01430	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GGC04_01435	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GGC04_01440	COG0402	S-adenosylhomocysteine deaminase activity
GGC04_01445	COG0557	exoribonuclease II activity
GGC04_01450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GGC04_01455	COG0051	transcription antitermination factor activity, RNA binding
GGC04_01465	COG0088	Forms part of the polypeptide exit tunnel
GGC04_01485	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GGC04_01490	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GGC04_01520	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GGC04_01535	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GGC04_01550	COG1841	ribosomal large subunit assembly
GGC04_01560	COG0201	protein transport
GGC04_01570	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GGC04_01575	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GGC04_01590	COG0203	ribosomal protein L17
GGC04_01600	COG0545	Peptidyl-prolyl cis-trans isomerase
GGC04_01615	COG2153	protein acetylation
GGC04_01625	COG0737	Belongs to the 5'-nucleotidase family
GGC04_01630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GGC04_01630	COG1648	precorrin-2 dehydrogenase activity
GGC04_01645	COG3273	potassium ion transport
GGC04_01645	COG0471	metal ion transport
GGC04_01650	COG0529	Catalyzes the synthesis of activated sulfate
GGC04_01660	COG0735	belongs to the Fur family
GGC04_01670	COG3437	response regulator, receiver
GGC04_01700	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GGC04_01705	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GGC04_01765	COG1410	methionine synthase
GGC04_01765	COG0646	methionine synthase
GGC04_01770	COG2239	Acts as a magnesium transporter
GGC04_01775	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC04_01785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC04_01790	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GGC04_01800	COG1137	ATPase activity
GGC04_01805	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GGC04_01815	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GGC04_01820	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GGC04_01820	COG0517	IMP dehydrogenase activity
GGC04_01830	COG1127	ABC transporter
GGC04_01835	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GGC04_01840	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GGC04_01845	COG2854	intermembrane phospholipid transfer
GGC04_01855	COG5007	Belongs to the BolA IbaG family
GGC04_01865	COG0204	Acyl-transferase
GGC04_01870	COG2235	arginine
GGC04_01890	COG0589	response to stress
GGC04_01915	COG0039	L-malate dehydrogenase activity
GGC04_01925	COG0251	oxidation-reduction process
GGC04_01930	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GGC04_01945	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GGC04_01950	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GGC04_01960	COG0564	pseudouridine synthase activity
GGC04_01965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GGC04_01975	COG4269	membrane
GGC04_01985	COG0525	valine-tRNA ligase activity
GGC04_01990	COG2927	DNA polymerase III (CHI subunit)
GGC04_02000	COG0795	lipopolysaccharide-transporting ATPase activity
GGC04_02005	COG0795	lipopolysaccharide-transporting ATPase activity
GGC04_02010	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GGC04_02015	COG1546	Belongs to the CinA family
GGC04_02020	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GGC04_02025	COG2137	regulation of response to DNA damage stimulus
GGC04_02035	COG0527	aspartate kinase activity
GGC04_02085	COG3630	sodium ion export across plasma membrane
GGC04_02090	COG0511	ligase activity, forming carbon-carbon bonds
GGC04_02090	COG5016	pyruvate
GGC04_02095	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GGC04_02100	COG2130	NADP-dependent
GGC04_02105	COG1238	metal cluster binding
GGC04_02110	COG0612	Peptidase, M16
GGC04_02115	COG2918	glutathione biosynthetic process
GGC04_02125	COG1854	S-ribosylhomocysteine lyase activity
GGC04_02140	COG0582	viral genome integration into host DNA
GGC04_02170	COG0328	RNA-DNA hybrid ribonuclease activity
GGC04_02185	COG3547	Transposase (IS116 IS110 IS902 family)
GGC04_02205	COG4251	negative regulation of phosphorylation
GGC04_02205	COG2203	Gaf domain
GGC04_02205	COG3706	GGDEF domain
GGC04_02205	COG5001	Diguanylate cyclase
GGC04_02215	COG1879	ABC-type sugar transport system periplasmic component
GGC04_02220	COG0840	transmembrane signaling receptor activity
GGC04_02240	COG0840	transmembrane signaling receptor activity
GGC04_02245	COG3706	GGDEF domain
GGC04_02245	COG5001	Diguanylate cyclase
GGC04_02245	COG4251	negative regulation of phosphorylation
GGC04_02245	COG2203	Gaf domain
GGC04_02275	COG0640	Transcriptional regulator
GGC04_02315	COG2003	Belongs to the UPF0758 family
GGC04_02325	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GGC04_02355	COG3437	response regulator, receiver
GGC04_02415	COG0473	3-isopropylmalate dehydrogenase activity
GGC04_02420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GGC04_02440	COG0583	DNA-binding transcription factor activity
GGC04_02445	COG1022	Amp-dependent synthetase and ligase
GGC04_02450	COG0028	Belongs to the TPP enzyme family
GGC04_02455	COG0440	acetolactate synthase activity
GGC04_02460	COG0584	glycerophosphoryl diester phosphodiesterase
GGC04_02465	COG2271	Major facilitator Superfamily
GGC04_02470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GGC04_02480	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GGC04_02490	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GGC04_02500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GGC04_02505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GGC04_02530	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GGC04_02535	COG1595	DNA-templated transcription, initiation
GGC04_02550	COG3086	response to oxidative stress
GGC04_02555	COG0481	GTPase activity
GGC04_02560	COG0681	Belongs to the peptidase S26 family
GGC04_02570	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GGC04_02575	COG1381	Involved in DNA repair and RecF pathway recombination
GGC04_02585	COG0736	holo-[acyl-carrier-protein] synthase activity
GGC04_02590	COG4999	Histidine kinase
GGC04_02590	COG3850	Histidine kinase
GGC04_02590	COG3437	response regulator, receiver
GGC04_02590	COG2205	protein histidine kinase activity
GGC04_02595	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GGC04_02600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GGC04_02605	COG3956	TIGRFAM MazG family protein
GGC04_02615	COG0148	phosphopyruvate hydratase activity
GGC04_02620	COG0617	tRNA 3'-terminal CCA addition
GGC04_02625	COG3409	Peptidoglycan-binding domain 1 protein
GGC04_02625	COG3267	Type II secretory pathway component ExeA
GGC04_02635	COG4991	sh3 domain protein
GGC04_02640	COG0306	phosphate transporter
GGC04_02645	COG1392	Phosphate transport regulator
GGC04_02650	COG3025	triphosphatase activity
GGC04_02655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GGC04_02665	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GGC04_02680	COG0745	RESPONSE REGULATOR receiver
GGC04_02710	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GGC04_02715	COG2860	membrane
GGC04_02720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GGC04_02725	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GGC04_02750	COG1846	Transcriptional regulator
GGC04_02755	COG0534	Mate efflux family protein
GGC04_02760	COG2204	response regulator
GGC04_02775	COG0667	Aldo Keto reductase
GGC04_02785	COG3066	DNA modification
GGC04_02800	COG0730	response to heat
GGC04_02810	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GGC04_02815	COG1283	sodium-dependent phosphate transmembrane transporter activity
GGC04_02820	COG0583	DNA-binding transcription factor activity
GGC04_02825	COG0640	Transcriptional regulator
GGC04_02830	COG0268	Binds directly to 16S ribosomal RNA
GGC04_02835	COG0728	peptidoglycan biosynthetic process
GGC04_02840	COG0196	riboflavin kinase activity
GGC04_02855	COG1047	Peptidyl-prolyl cis-trans
GGC04_02860	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GGC04_02865	COG1966	Carbon starvation protein
GGC04_02875	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GGC04_02880	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GGC04_02885	COG2971	BadF BadG BcrA BcrD
GGC04_02895	COG1737	Transcriptional regulator
GGC04_02900	COG1472	Belongs to the glycosyl hydrolase 3 family
GGC04_02905	COG3279	Response regulator of the LytR AlgR family
GGC04_02910	COG3275	phosphorelay sensor kinase activity
GGC04_02915	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GGC04_02920	COG0287	Prephenate dehydrogenase
GGC04_02920	COG1605	Chorismate mutase
GGC04_02925	COG0739	heme binding
GGC04_02935	COG0488	(ABC) transporter
GGC04_02940	COG0741	lytic transglycosylase activity
GGC04_02945	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GGC04_02950	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GGC04_02955	COG5001	Diguanylate cyclase
GGC04_02960	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GGC04_02965	COG1605	Chorismate mutase
GGC04_02965	COG0077	Prephenate dehydratase
GGC04_02970	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GGC04_02975	COG0741	lytic transglycosylase activity
GGC04_02980	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GGC04_02985	COG0564	pseudouridine synthase activity
GGC04_02995	COG0542	response to heat
GGC04_03035	COG0483	inositol monophosphate 1-phosphatase activity
GGC04_03045	COG1959	2 iron, 2 sulfur cluster binding
GGC04_03055	COG0822	iron-sulfur transferase activity
GGC04_03075	COG0633	Ferredoxin
GGC04_03080	COG2975	iron-sulfur cluster assembly
GGC04_03085	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GGC04_03095	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GGC04_03100	COG0583	DNA-binding transcription factor activity
GGC04_03110	COG0583	DNA-binding transcription factor activity
GGC04_03115	COG1022	Amp-dependent synthetase and ligase
GGC04_03120	COG2169	Transcriptional regulator
GGC04_03150	COG4964	Belongs to the GSP D family
GGC04_03200	COG2169	Transcriptional regulator
GGC04_03205	COG1486	melibiose metabolic process
GGC04_03210	COG2211	Major facilitator Superfamily
GGC04_03220	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GGC04_03220	COG3408	Glycogen debranching enzyme
GGC04_03235	COG1309	transcriptional regulator
GGC04_03240	COG0531	amino acid
GGC04_03245	COG2731	YhcH YjgK YiaL family protein
GGC04_03250	COG3250	beta-galactosidase activity
GGC04_03255	COG1609	Transcriptional regulator
GGC04_03260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GGC04_03265	COG1085	galactose-1-phosphate uridylyltransferase
GGC04_03275	COG2017	converts alpha-aldose to the beta-anomer
GGC04_03285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GGC04_03295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC04_03295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC04_03295	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC04_03300	COG2207	Transcriptional regulator
GGC04_03310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC04_03320	COG2171	N-acyltransferase activity
GGC04_03325	COG0450	alkyl hydroperoxide reductase
GGC04_03330	COG0583	DNA-binding transcription factor activity
GGC04_03335	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GGC04_03360	COG0517	IMP dehydrogenase activity
GGC04_03365	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GGC04_03375	COG1862	Preprotein translocase
GGC04_03380	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GGC04_03385	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GGC04_03400	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
GGC04_03405	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GGC04_03420	COG0745	RESPONSE REGULATOR receiver
GGC04_03425	COG5002	protein histidine kinase activity
GGC04_03435	COG0248	Ppx GppA phosphatase
GGC04_03440	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GGC04_03445	COG0573	inorganic phosphate transmembrane transporter activity
GGC04_03450	COG0581	inorganic phosphate transmembrane transporter activity
GGC04_03455	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GGC04_03460	COG0704	Plays a role in the regulation of phosphate uptake
GGC04_03475	COG3141	response to X-ray
GGC04_03480	COG1309	transcriptional regulator
GGC04_03485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC04_03505	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GGC04_03510	COG1074	ATP-dependent DNA helicase activity
GGC04_03515	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GGC04_03535	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GGC04_03540	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GGC04_03545	COG2166	iron-sulfur cluster assembly
GGC04_03555	COG1426	Protein conserved in bacteria
GGC04_03565	COG0124	histidyl-tRNA synthetase
GGC04_03570	COG2976	Protein conserved in bacteria
GGC04_03575	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GGC04_03580	COG1160	GTP binding
GGC04_03590	COG2199	diguanylate cyclase activity
GGC04_03590	COG2203	Gaf domain
GGC04_03605	COG0517	IMP dehydrogenase activity
GGC04_03605	COG0516	GMP reductase activity
GGC04_03620	COG1584	GPR1 FUN34 yaaH family protein
GGC04_03625	COG1115	amino acid carrier protein
GGC04_03635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGC04_03655	COG2873	o-acetylhomoserine
GGC04_03660	COG0835	chemotaxis
GGC04_03660	COG0784	Response regulator, receiver
GGC04_03665	COG0204	Acyl-transferase
GGC04_03685	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GGC04_03690	COG0668	transmembrane transport
GGC04_03710	COG2867	negative regulation of translational initiation
GGC04_03720	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GGC04_03725	COG0497	DNA recombination
GGC04_03735	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GGC04_03740	COG1301	dicarboxylic acid transport
GGC04_03745	COG0443	Heat shock 70 kDa protein
GGC04_03760	COG4970	Tfp pilus assembly protein FimT
GGC04_03780	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GGC04_03785	COG0590	tRNA wobble adenosine to inosine editing
GGC04_03795	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GGC04_03800	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GGC04_03800	COG0047	phosphoribosylformylglycinamidine synthase activity
GGC04_03825	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GGC04_03830	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GGC04_03835	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GGC04_03840	COG1187	pseudouridine synthase activity
GGC04_03845	COG2840	Smr protein MutS2
GGC04_03870	COG3104	oligopeptide transport
GGC04_03875	COG0367	asparagine synthase
GGC04_03880	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GGC04_03880	COG4651	solute:proton antiporter activity
GGC04_03885	COG1940	carbohydrate kinase activity
GGC04_03885	COG1846	Transcriptional regulator
GGC04_03890	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GGC04_03895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGC04_03895	COG2190	(PTS) system
GGC04_03895	COG1263	PTS System
GGC04_03915	COG0716	FMN binding
GGC04_03925	COG0596	Alpha beta hydrolase
GGC04_03930	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GGC04_03935	COG0033	Phosphoglucomutase
GGC04_03945	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GGC04_03960	COG2009	succinate dehydrogenase
GGC04_03965	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GGC04_03970	COG1053	succinate dehydrogenase
GGC04_03975	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GGC04_03980	COG0567	Dehydrogenase, E1 component
GGC04_03985	COG0508	dehydrogenase complex catalyzes the overall conversion of
GGC04_04000	COG1943	Transposase
GGC04_04030	COG3098	single-species biofilm formation
GGC04_04035	COG0564	pseudouridine synthase activity
GGC04_04045	COG0142	geranyltranstransferase activity
GGC04_04055	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GGC04_04065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GGC04_04065	COG0301	tRNA thio-modification
GGC04_04075	COG0583	DNA-binding transcription factor activity
GGC04_04100	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GGC04_04105	COG1611	Belongs to the LOG family
GGC04_04110	COG3706	GGDEF domain
GGC04_04110	COG0745	RESPONSE REGULATOR receiver
GGC04_04130	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GGC04_04145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GGC04_04150	COG1393	Belongs to the ArsC family
GGC04_04180	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GGC04_04185	COG0437	4 iron, 4 sulfur cluster binding
GGC04_04190	COG3301	Polysulphide reductase, NrfD
GGC04_04195	COG1138	Cytochrome C-type biogenesis protein
GGC04_04200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GGC04_04205	COG4235	cytochrome complex assembly
GGC04_04205	COG3088	subunit of a heme lyase
GGC04_04215	COG2837	iron assimilation
GGC04_04230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GGC04_04240	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GGC04_04250	COG1516	flagellar protein fliS
GGC04_04260	COG2204	response regulator
GGC04_04265	COG4191	Histidine kinase
GGC04_04270	COG2204	response regulator
GGC04_04275	COG1677	Flagellar hook-basal body complex protein FliE
GGC04_04285	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GGC04_04335	COG1987	bacterial-type flagellum assembly
GGC04_04340	COG1684	flagellar biosynthetic protein fliR
GGC04_04355	COG2890	protein-(glutamine-N5) methyltransferase activity
GGC04_04360	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GGC04_04370	COG2860	membrane
GGC04_04375	COG3101	peptidyl-lysine hydroxylation
GGC04_04405	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GGC04_04410	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GGC04_04415	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GGC04_04430	COG0101	tRNA pseudouridine synthase activity
GGC04_04440	COG0285	dihydrofolate synthase activity
GGC04_04445	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GGC04_04450	COG1286	toxin biosynthetic process
GGC04_04455	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GGC04_04460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GGC04_04465	COG1121	(ABC) transporter
GGC04_04470	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GGC04_04475	COG4977	sequence-specific DNA binding
GGC04_04480	COG1918	ferrous iron import across plasma membrane
GGC04_04485	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GGC04_04500	COG0018	arginyl-trna synthetase
GGC04_04505	COG3102	Protein conserved in bacteria
GGC04_04510	COG1025	Belongs to the peptidase M16 family
GGC04_04515	COG2062	phosphohistidine phosphatase, SixA
GGC04_04530	COG0455	bacterial-type flagellum organization
GGC04_04545	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GGC04_04550	COG0643	Histidine kinase
GGC04_04550	COG2198	Histidine kinase
GGC04_04555	COG2201	protein-glutamate methylesterase activity
GGC04_04560	COG1192	Involved in chromosome partitioning
GGC04_04570	COG0835	chemotaxis
GGC04_04580	COG4133	protoheme IX ABC transporter activity
GGC04_04585	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GGC04_04590	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GGC04_04595	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GGC04_04605	COG1138	Cytochrome C-type biogenesis protein
GGC04_04610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GGC04_04615	COG3088	subunit of a heme lyase
GGC04_04615	COG4235	cytochrome complex assembly
GGC04_04625	COG2853	Lipoprotein
GGC04_04630	COG2067	long-chain fatty acid transport protein
GGC04_04635	COG2067	long-chain fatty acid transport protein
GGC04_04650	COG0183	Belongs to the thiolase family
GGC04_04660	COG0778	Nitroreductase
GGC04_04665	COG0583	DNA-binding transcription factor activity
GGC04_04670	COG0745	RESPONSE REGULATOR receiver
GGC04_04685	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GGC04_04695	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GGC04_04735	COG0745	RESPONSE REGULATOR receiver
GGC04_04740	COG2205	protein histidine kinase activity
GGC04_04745	COG1653	transport
GGC04_04760	COG3842	ATPase activity
GGC04_04765	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GGC04_04770	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GGC04_04775	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GGC04_04785	COG2204	response regulator
GGC04_04810	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GGC04_04815	COG0776	regulation of translation
GGC04_04820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GGC04_04825	COG1555	photosystem II stabilization
GGC04_04835	COG0539	negative regulation of cytoplasmic translation
GGC04_04845	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GGC04_04850	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GGC04_04855	COG0284	orotidine-5'-phosphate decarboxylase activity
GGC04_04890	COG4120	Belongs to the binding-protein-dependent transport system permease family
GGC04_04900	COG3706	GGDEF domain
GGC04_04905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GGC04_04925	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GGC04_04930	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GGC04_04940	COG0252	asparaginase activity
GGC04_04945	COG0616	signal peptide processing
GGC04_04950	COG1902	pentaerythritol trinitrate reductase activity
GGC04_04950	COG0446	pyridine nucleotide-disulphide oxidoreductase
GGC04_04955	COG0788	formyltetrahydrofolate deformylase activity
GGC04_04965	COG1199	ATP-dependent helicase activity
GGC04_04970	COG1214	PFAM Peptidase M22, glycoprotease
GGC04_04985	COG2267	carboxylic ester hydrolase activity
GGC04_04990	COG0318	PFAM AMP-dependent synthetase and ligase
GGC04_04995	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GGC04_05000	COG0659	secondary active sulfate transmembrane transporter activity
GGC04_05005	COG1530	ribonuclease E activity
GGC04_05010	COG0564	pseudouridine synthase activity
GGC04_05015	COG0424	maF-like protein
GGC04_05020	COG1399	metal-binding, possibly nucleic acid-binding protein
GGC04_05035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GGC04_05060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GGC04_05065	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GGC04_05070	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GGC04_05075	COG0470	DNA polymerase III
GGC04_05080	COG0084	hydrolase, TatD family'
GGC04_05085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGC04_05085	COG1263	PTS System
GGC04_05095	COG1943	Transposase
GGC04_05105	COG0733	neurotransmitter:sodium symporter activity
GGC04_05120	COG4667	esterase of the alpha-beta hydrolase superfamily
GGC04_05125	COG0469	pyruvate kinase activity
GGC04_05130	COG1940	carbohydrate kinase activity
GGC04_05135	COG0835	chemotaxis
GGC04_05135	COG0784	Response regulator, receiver
GGC04_05155	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_05160	COG0616	signal peptide processing
GGC04_05165	COG0513	Belongs to the DEAD box helicase family
GGC04_05180	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GGC04_05185	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GGC04_05195	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GGC04_05200	COG0436	Aminotransferase
GGC04_05205	COG1169	isochorismate synthase
GGC04_05210	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GGC04_05215	COG0596	Alpha beta hydrolase
GGC04_05225	COG1441	menaquinone biosynthetic process
GGC04_05240	COG2855	membrane
GGC04_05245	COG0477	Major facilitator Superfamily
GGC04_05270	COG1522	sequence-specific DNA binding
GGC04_05285	COG1946	Acyl-CoA thioesterase
GGC04_05290	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GGC04_05305	COG3706	GGDEF domain
GGC04_05355	COG1414	Transcriptional regulator
GGC04_05360	COG0280	phosphate acetyltransferase
GGC04_05365	COG0730	response to heat
GGC04_05385	COG2855	membrane
GGC04_05400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGC04_05405	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GGC04_05410	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GGC04_05430	COG1472	Belongs to the glycosyl hydrolase 3 family
GGC04_05435	COG3876	Protein conserved in bacteria
GGC04_05445	COG1215	transferase activity, transferring glycosyl groups
GGC04_05460	COG3397	chitin binding
GGC04_05465	COG1770	oligopeptidase
GGC04_05475	COG3227	Zinc metalloprotease (Elastase)
GGC04_05485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC04_05495	COG0577	efflux transmembrane transporter activity
GGC04_05505	COG1136	(ABC) transporter
GGC04_05505	COG0577	efflux transmembrane transporter activity
GGC04_05525	COG0330	HflC and HflK could
GGC04_05535	COG0840	transmembrane signaling receptor activity
GGC04_05540	COG1404	Belongs to the peptidase S8 family
GGC04_05565	COG3706	GGDEF domain
GGC04_05570	COG2067	long-chain fatty acid transport protein
GGC04_05585	COG0601	transmembrane transport
GGC04_05590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GGC04_05595	COG0444	Belongs to the ABC transporter superfamily
GGC04_05605	COG0435	Glutathione S-transferase
GGC04_05610	COG3706	GGDEF domain
GGC04_05615	COG0280	phosphate acetyltransferase
GGC04_05615	COG0857	belongs to the CobB CobQ family
GGC04_05625	COG3092	negative regulation of chromosome organization
GGC04_05630	COG0686	Belongs to the AlaDH PNT family
GGC04_05640	COG1674	ftsk spoiiie
GGC04_05655	COG2186	Transcriptional regulator
GGC04_05670	COG0537	adenosine 5'-monophosphoramidase activity
GGC04_05700	COG1252	NADH dehydrogenase
GGC04_05705	COG1943	Transposase
GGC04_05725	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GGC04_05735	COG4591	ABC-type transport system involved in lipoprotein release permease component
GGC04_05740	COG1136	(ABC) transporter
GGC04_05745	COG4591	ABC-type transport system involved in lipoprotein release permease component
GGC04_05755	COG0658	competence protein
GGC04_05755	COG2333	competence protein COMEC
GGC04_05760	COG1132	(ABC) transporter
GGC04_05775	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GGC04_05780	COG2719	SpoVR family
GGC04_05785	COG2718	Belongs to the UPF0229 family
GGC04_05790	COG2766	serine protein kinase
GGC04_05795	COG3713	MltA-interacting MipA family protein
GGC04_05810	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GGC04_05825	COG1882	Formate acetyltransferase
GGC04_05845	COG4215	(ABC) transporter
GGC04_05860	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GGC04_06000	COG3772	lysozyme
GGC04_06015	COG4695	Portal protein
GGC04_06055	COG4386	tail sheath protein
GGC04_06090	COG3646	Phage regulatory protein
GGC04_06120	COG1012	belongs to the aldehyde dehydrogenase family
GGC04_06120	COG1454	alcohol dehydrogenase
GGC04_06125	COG1737	Transcriptional regulator
GGC04_06130	COG0076	glutamate decarboxylase activity
GGC04_06140	COG2431	L-lysine efflux transmembrane transporter activity
GGC04_06150	COG3070	regulator of competence-specific genes
GGC04_06165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC04_06165	COG4191	Histidine kinase
GGC04_06175	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GGC04_06185	COG1032	radical SAM domain protein
GGC04_06205	COG0583	DNA-binding transcription factor activity
GGC04_06210	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GGC04_06215	COG1764	response to oxidative stress
GGC04_06220	COG1846	Transcriptional regulator
GGC04_06230	COG0583	DNA-binding transcription factor activity
GGC04_06240	COG0673	inositol 2-dehydrogenase activity
GGC04_06245	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GGC04_06265	COG0840	transmembrane signaling receptor activity
GGC04_06270	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GGC04_06285	COG3152	Membrane
GGC04_06330	COG1858	cytochrome C peroxidase
GGC04_06345	COG0443	Heat shock 70 kDa protein
GGC04_06395	COG1643	Atp-dependent helicase
GGC04_06405	COG1301	dicarboxylic acid transport
GGC04_06410	COG0159	tryptophan synthase activity
GGC04_06415	COG0133	tryptophan synthase activity
GGC04_06420	COG0135	phosphoribosylanthranilate isomerase activity
GGC04_06420	COG0134	indole-3-glycerol-phosphate synthase activity
GGC04_06425	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GGC04_06430	COG0512	Glutamine amidotransferase of anthranilate synthase
GGC04_06435	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GGC04_06445	COG0613	PHP domain protein
GGC04_06450	COG0009	L-threonylcarbamoyladenylate synthase
GGC04_06465	COG1187	pseudouridine synthase activity
GGC04_06470	COG0384	phenazine biosynthesis protein PhzF
GGC04_06480	COG2814	Major facilitator Superfamily
GGC04_06485	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GGC04_06490	COG4988	ABC transporter
GGC04_06495	COG0492	ferredoxin-NADP+ reductase activity
GGC04_06510	COG2175	clavaminate synthase activity
GGC04_06525	COG0612	Peptidase, M16
GGC04_06535	COG2949	membrane
GGC04_06545	COG0281	malic enzyme
GGC04_06550	COG1643	Atp-dependent helicase
GGC04_06565	COG1448	Aminotransferase
GGC04_06570	COG3437	response regulator, receiver
GGC04_06570	COG2770	Histidine kinase
GGC04_06580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGC04_06595	COG0017	Asparaginyl-tRNA synthetase
GGC04_06615	COG0814	amino acid
GGC04_06625	COG1760	l-serine dehydratase
GGC04_06630	COG0814	amino acid
GGC04_06635	COG0494	nUDIX hydrolase
GGC04_06645	COG2205	protein histidine kinase activity
GGC04_06645	COG0784	Response regulator, receiver
GGC04_06665	COG3106	COG3106 Predicted ATPase
GGC04_06675	COG3283	Transcriptional regulator of aromatic amino acids metabolism
GGC04_06680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GGC04_06700	COG3706	GGDEF domain
GGC04_06705	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GGC04_06730	COG2989	Protein conserved in bacteria
GGC04_06735	COG3108	Peptidase M15
GGC04_06740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GGC04_06755	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GGC04_06790	COG4667	esterase of the alpha-beta hydrolase superfamily
GGC04_06795	COG0783	Belongs to the Dps family
GGC04_06805	COG0531	amino acid
GGC04_06810	COG2962	Rard protein
GGC04_06870	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GGC04_06985	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GGC04_07020	COG0546	phosphoglycolate phosphatase activity
GGC04_07025	COG4628	conserved protein (DUF2132)
GGC04_07035	COG0456	acetyltransferase
GGC04_07045	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GGC04_07055	COG0730	response to heat
GGC04_07065	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_07075	COG2824	Alkylphosphonate utilization operon protein PhnA
GGC04_07090	COG0456	acetyltransferase
GGC04_07110	COG3040	lipid binding
GGC04_07125	COG3122	Protein conserved in bacteria
GGC04_07185	COG0454	-acetyltransferase
GGC04_07190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GGC04_07215	COG0456	acetyltransferase
GGC04_07235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGC04_07250	COG2195	Cleaves the N-terminal amino acid of tripeptides
GGC04_07260	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GGC04_07270	COG0625	glutathione transferase activity
GGC04_07285	COG2885	chlorophyll binding
GGC04_07300	COG0277	FAD linked oxidase domain protein
GGC04_07300	COG0247	lactate metabolic process
GGC04_07315	COG2986	histidine ammonia-lyase
GGC04_07325	COG0010	Belongs to the arginase family
GGC04_07330	COG1228	amidohydrolase
GGC04_07335	COG2188	Transcriptional regulator
GGC04_07340	COG4326	sporulation control protein
GGC04_07360	COG0500	methyltransferase
GGC04_07380	COG1346	cytolysis
GGC04_07390	COG2925	Exonuclease
GGC04_07400	COG0702	epimerase
GGC04_07405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GGC04_07415	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GGC04_07425	COG0406	alpha-ribazole phosphatase activity
GGC04_07460	COG3706	GGDEF domain
GGC04_07470	COG2814	Major facilitator Superfamily
GGC04_07480	COG1119	ATPase activity
GGC04_07490	COG5002	protein histidine kinase activity
GGC04_07490	COG0784	Response regulator, receiver
GGC04_07500	COG1451	nucleotide metabolic process
GGC04_07515	COG3063	Type IV pilus biogenesis stability protein PilW
GGC04_07520	COG0508	dehydrogenase complex catalyzes the overall conversion of
GGC04_07520	COG0596	Alpha beta hydrolase
GGC04_07540	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GGC04_07555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC04_07580	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GGC04_07585	COG0515	serine threonine protein kinase
GGC04_07685	COG3501	Rhs element vgr protein
GGC04_07700	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GGC04_07705	COG0372	Belongs to the citrate synthase family
GGC04_07715	COG2828	Protein conserved in bacteria
GGC04_07735	COG0561	phosphatase activity
GGC04_07740	COG0602	queuosine metabolic process
GGC04_07775	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GGC04_07780	COG0840	transmembrane signaling receptor activity
GGC04_07785	COG1254	Belongs to the acylphosphatase family
GGC04_07790	COG2920	part of a sulfur-relay system
GGC04_07795	COG0670	Belongs to the BI1 family
GGC04_07800	COG1126	abc transporter atp-binding protein
GGC04_07805	COG0765	amino acid transport
GGC04_07810	COG4597	amino acid ABC transporter
GGC04_07815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC04_07825	COG1666	GTP binding
GGC04_07830	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GGC04_07865	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GGC04_07865	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GGC04_07870	COG3008	intermembrane lipid transfer
GGC04_07875	COG2995	paraquat-inducible protein a
GGC04_07880	COG1132	(ABC) transporter
GGC04_07885	COG1956	GAF domain-containing protein
GGC04_07890	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GGC04_07905	COG0308	aminopeptidase N
GGC04_07920	COG0167	dihydroorotate dehydrogenase activity
GGC04_07930	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GGC04_07930	COG0116	Belongs to the methyltransferase superfamily
GGC04_07940	COG0488	(ABC) transporter
GGC04_07955	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GGC04_07960	COG1067	ATP-dependent peptidase activity
GGC04_08015	COG0789	Transcriptional regulator
GGC04_08050	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GGC04_08070	COG0840	transmembrane signaling receptor activity
GGC04_08205	COG3424	synthase
GGC04_08220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GGC04_08245	COG1132	(ABC) transporter
GGC04_08360	COG3278	Belongs to the heme-copper respiratory oxidase family
GGC04_08375	COG2010	Cytochrome c
GGC04_08385	COG2217	Heavy metal translocating P-type atpase
GGC04_08400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GGC04_08405	COG0589	response to stress
GGC04_08430	COG3842	ATPase activity
GGC04_08435	COG1176	ABC-type spermidine putrescine transport system, permease component I
GGC04_08440	COG1177	transmembrane transport
GGC04_08445	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GGC04_08450	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GGC04_08455	COG2199	diguanylate cyclase activity
GGC04_08460	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GGC04_08465	COG0004	ammonium transporteR
GGC04_08480	COG0437	4 iron, 4 sulfur cluster binding
GGC04_08485	COG3383	formate dehydrogenase (NAD+) activity
GGC04_08485	COG0243	molybdopterin cofactor binding
GGC04_08515	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GGC04_08530	COG3038	cytochrome b561
GGC04_08555	COG0583	DNA-binding transcription factor activity
GGC04_08565	COG0583	DNA-binding transcription factor activity
GGC04_08570	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GGC04_08590	COG0069	glutamate synthase activity
GGC04_08595	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_08610	COG0488	(ABC) transporter
GGC04_08620	COG1595	DNA-templated transcription, initiation
GGC04_08635	COG3852	Histidine kinase
GGC04_08650	COG4662	Binding-protein-dependent transport system inner membrane component
GGC04_08655	COG3842	ATPase activity
GGC04_08660	COG0746	molybdenum cofactor guanylyltransferase activity
GGC04_08665	COG0303	'Molybdopterin
GGC04_08695	COG1940	carbohydrate kinase activity
GGC04_08710	COG0840	transmembrane signaling receptor activity
GGC04_08715	COG0791	NLP P60 protein
GGC04_08735	COG0307	riboflavin synthase, alpha
GGC04_08785	COG2204	response regulator
GGC04_08795	COG0438	transferase activity, transferring glycosyl groups
GGC04_08830	COG0297	glycogen (starch) synthase activity
GGC04_08840	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GGC04_08880	COG4774	siderophore transport
GGC04_08900	COG4615	Cyclic peptide transporter
GGC04_08910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GGC04_08915	COG1120	ATPase activity
GGC04_08920	COG2977	Belongs to the P-Pant transferase superfamily
GGC04_08925	COG1929	Belongs to the glycerate kinase type-1 family
GGC04_08930	COG3835	regulator
GGC04_08940	COG2814	Major facilitator Superfamily
GGC04_08950	COG1288	antiporter activity
GGC04_08960	COG2186	Transcriptional regulator
GGC04_08970	COG3713	MltA-interacting MipA family protein
GGC04_08980	COG0745	RESPONSE REGULATOR receiver
GGC04_08990	COG0583	DNA-binding transcription factor activity
GGC04_09010	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GGC04_09030	COG2116	formate transmembrane transporter activity
GGC04_09035	COG2146	nitrite reductase [NAD(P)H] activity
GGC04_09040	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GGC04_09070	COG4565	transcriptional regulatory protein
GGC04_09075	COG3290	protein histidine kinase activity
GGC04_09095	COG0848	biopolymer transport protein
GGC04_09100	COG0811	peptide transport
GGC04_09105	COG0811	peptide transport
GGC04_09115	COG4774	siderophore transport
GGC04_09125	COG2205	protein histidine kinase activity
GGC04_09130	COG0745	RESPONSE REGULATOR receiver
GGC04_09135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GGC04_09175	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GGC04_09180	COG1328	CTP reductase activity
GGC04_09185	COG0840	transmembrane signaling receptor activity
GGC04_09195	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GGC04_09205	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GGC04_09210	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GGC04_09215	COG0633	Ferredoxin
GGC04_09240	COG0019	diaminopimelate decarboxylase activity
GGC04_09285	COG1136	(ABC) transporter
GGC04_09290	COG0534	Mate efflux family protein
GGC04_09295	COG0702	epimerase
GGC04_09305	COG2814	Major facilitator Superfamily
GGC04_09315	COG1061	Type III restriction enzyme res subunit
GGC04_09330	COG2205	protein histidine kinase activity
GGC04_09355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGC04_09360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC04_09380	COG0463	Glycosyl transferase, family 2
GGC04_09415	COG0455	bacterial-type flagellum organization
GGC04_09430	COG2188	Transcriptional regulator
GGC04_09435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGC04_09435	COG1263	PTS System
GGC04_09440	COG1621	beta-fructofuranosidase activity
GGC04_09450	COG0583	DNA-binding transcription factor activity
GGC04_09455	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GGC04_09485	COG4221	oxidoreductase activity
GGC04_09520	COG0307	riboflavin synthase, alpha
GGC04_09570	COG0242	peptide deformylase activity
GGC04_09575	COG0519	Catalyzes the synthesis of GMP from XMP
GGC04_09590	COG4580	involved in the transport of maltose and maltodextrins
GGC04_09595	COG0778	Nitroreductase
GGC04_09650	COG3300	MHYT domain
GGC04_09650	COG5001	Diguanylate cyclase
GGC04_09680	COG1115	amino acid carrier protein
GGC04_09685	COG1280	lysine exporter protein (LysE YggA)
GGC04_09690	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GGC04_09695	COG0352	thiamine-phosphate diphosphorylase activity
GGC04_09700	COG0583	DNA-binding transcription factor activity
GGC04_09725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GGC04_09735	COG1012	belongs to the aldehyde dehydrogenase family
GGC04_09745	COG0583	DNA-binding transcription factor activity
GGC04_09800	COG1609	Transcriptional regulator
GGC04_09815	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GGC04_09820	COG1609	Transcriptional regulator
GGC04_09830	COG0642	Histidine kinase
GGC04_09835	COG0745	RESPONSE REGULATOR receiver
GGC04_09855	COG1858	cytochrome C peroxidase
GGC04_09870	COG2205	protein histidine kinase activity
GGC04_09870	COG0784	Response regulator, receiver
GGC04_09875	COG0488	(ABC) transporter
GGC04_09880	COG3437	response regulator, receiver
GGC04_09890	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GGC04_09900	COG2223	nitrite transmembrane transporter activity
GGC04_09905	COG1216	Glycosyl transferase, family 2
GGC04_09915	COG0673	inositol 2-dehydrogenase activity
GGC04_09920	COG3718	enzyme involved in inositol metabolism
GGC04_09945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC04_09950	COG0673	inositol 2-dehydrogenase activity
GGC04_09955	COG3962	Belongs to the TPP enzyme family
GGC04_09970	COG2814	Major facilitator Superfamily
GGC04_09970	COG0477	Major facilitator Superfamily
GGC04_09990	COG0183	Belongs to the thiolase family
GGC04_09995	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GGC04_10035	COG3962	Belongs to the TPP enzyme family
GGC04_10040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC04_10050	COG1129	ABC transporter
GGC04_10055	COG4211	Belongs to the binding-protein-dependent transport system permease family
GGC04_10065	COG0277	FAD linked oxidase domain protein
GGC04_10075	COG0583	DNA-binding transcription factor activity
GGC04_10095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC04_10100	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GGC04_10120	COG1621	beta-fructofuranosidase activity
GGC04_10135	COG1263	PTS System
GGC04_10135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGC04_10145	COG1335	isochorismatase
GGC04_10150	COG1741	Belongs to the pirin family
GGC04_10190	COG4974	Belongs to the 'phage' integrase family
GGC04_10200	COG1733	regulation of RNA biosynthetic process
GGC04_10210	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GGC04_10230	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GGC04_10235	COG0072	phenylalanine-tRNA ligase activity
GGC04_10235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GGC04_10245	COG3706	GGDEF domain
GGC04_10270	COG2133	pyrroloquinoline quinone binding
GGC04_10280	COG1902	pentaerythritol trinitrate reductase activity
GGC04_10310	COG0322	excinuclease ABC activity
GGC04_10315	COG2197	response regulator
GGC04_10330	COG0417	DNA replication proofreading
GGC04_10345	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GGC04_10350	COG3099	Belongs to the UPF0263 family
GGC04_10385	COG1607	acyl-coa hydrolase
GGC04_10390	COG2350	Protein conserved in bacteria
GGC04_10405	COG3313	Fe-S protein
GGC04_10415	COG4134	Bacterial extracellular solute-binding protein
GGC04_10420	COG4135	transport system, permease component
GGC04_10425	COG4136	ATPase activity
GGC04_10430	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GGC04_10440	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GGC04_10445	COG0564	pseudouridine synthase activity
GGC04_10450	COG0733	neurotransmitter:sodium symporter activity
GGC04_10460	COG0626	cystathionine gamma-synthase activity
GGC04_10465	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GGC04_10470	COG5380	lipid catabolic process
GGC04_10475	COG2818	Glycosylase
GGC04_10490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC04_10495	COG1983	PspC domain protein
GGC04_10505	COG1842	Phage shock protein A
GGC04_10510	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GGC04_10520	COG4168	peptide transport system, permease
GGC04_10525	COG4171	peptide transport system, permease
GGC04_10535	COG4172	Belongs to the ABC transporter superfamily
GGC04_10550	COG1227	inorganic diphosphatase activity
GGC04_10560	COG0217	transcriptional regulatory protein
GGC04_10565	COG0140	phosphoribosyl-ATP diphosphatase activity
GGC04_10565	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GGC04_10570	COG0107	imidazoleglycerol-phosphate synthase activity
GGC04_10575	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GGC04_10580	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GGC04_10585	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GGC04_10585	COG0131	Imidazoleglycerol-phosphate dehydratase
GGC04_10595	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GGC04_10605	COG1757	Na H antiporter
GGC04_10615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC04_10625	COG0482	sulfurtransferase activity
GGC04_10635	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GGC04_10645	COG2268	Band 7 protein
GGC04_10655	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GGC04_10670	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_10690	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GGC04_10695	COG2226	methyltransferase
GGC04_10695	COG1073	alpha beta
GGC04_10700	COG0156	8-amino-7-oxononanoate synthase activity
GGC04_10710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GGC04_10725	COG1199	ATP-dependent helicase activity
GGC04_10730	COG0730	response to heat
GGC04_10745	COG2850	peptidyl-arginine hydroxylation
GGC04_10750	COG0840	transmembrane signaling receptor activity
GGC04_10755	COG0708	Exodeoxyribonuclease III
GGC04_10760	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GGC04_10765	COG1960	acyl-CoA dehydrogenase activity
GGC04_10785	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GGC04_10790	COG0463	Glycosyl transferase, family 2
GGC04_10795	COG0745	RESPONSE REGULATOR receiver
GGC04_10800	COG3850	Histidine kinase
GGC04_10800	COG5002	protein histidine kinase activity
GGC04_10815	COG1940	carbohydrate kinase activity
GGC04_10830	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GGC04_10835	COG1881	PFAM PEBP family protein
GGC04_10840	COG1902	pentaerythritol trinitrate reductase activity
GGC04_10860	COG0784	Response regulator, receiver
GGC04_10860	COG5002	protein histidine kinase activity
GGC04_10880	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GGC04_10885	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GGC04_10890	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GGC04_10895	COG2885	chlorophyll binding
GGC04_10915	COG0811	peptide transport
GGC04_10920	COG0824	Thioesterase
GGC04_10930	COG4890	Cyd operon protein YbgT
GGC04_10935	COG1294	oxidase, subunit
GGC04_10940	COG1271	oxidase subunit
GGC04_10945	COG2255	four-way junction helicase activity
GGC04_10950	COG0632	four-way junction helicase activity
GGC04_10955	COG0840	transmembrane signaling receptor activity
GGC04_10960	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GGC04_10980	COG4221	oxidoreductase activity
GGC04_10995	COG0243	molybdopterin cofactor binding
GGC04_11000	COG3005	denitrification pathway
GGC04_11005	COG4459	periplasmic nitrate reductase
GGC04_11010	COG0390	transport system, permease component
GGC04_11020	COG2116	formate transmembrane transporter activity
GGC04_11045	COG0542	response to heat
GGC04_11050	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GGC04_11055	COG1278	Cold shock
GGC04_11065	COG1187	pseudouridine synthase activity
GGC04_11075	COG1801	Protein of unknown function DUF72
GGC04_11085	COG0500	methyltransferase
GGC04_11090	COG4067	protein conserved in archaea
GGC04_11090	COG0189	ligase activity
GGC04_11120	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GGC04_11125	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GGC04_11135	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GGC04_11140	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GGC04_11145	COG0745	RESPONSE REGULATOR receiver
GGC04_11160	COG3070	regulator of competence-specific genes
GGC04_11185	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GGC04_11190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GGC04_11215	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GGC04_11220	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GGC04_11225	COG1435	thymidine kinase activity
GGC04_11230	COG0215	cysteine-tRNA ligase activity
GGC04_11235	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GGC04_11245	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GGC04_11250	COG3012	SEC-C Motif Domain Protein
GGC04_11255	COG3139	Protein of unknown function (DUF1315)
GGC04_11265	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GGC04_11280	COG0840	transmembrane signaling receptor activity
GGC04_11285	COG2226	methyltransferase
GGC04_11305	COG1785	Belongs to the alkaline phosphatase family
GGC04_11325	COG0668	transmembrane transport
GGC04_11330	COG2983	Belongs to the UPF0260 family
GGC04_11345	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GGC04_11350	COG0583	DNA-binding transcription factor activity
GGC04_11355	COG2951	lytic endotransglycosylase activity
GGC04_11360	COG3100	YcgL domain-containing protein
GGC04_11365	COG0850	regulation of cytokinetic process
GGC04_11370	COG2894	cell division
GGC04_11380	COG1454	alcohol dehydrogenase
GGC04_11380	COG1012	belongs to the aldehyde dehydrogenase family
GGC04_11385	COG2095	MarC family integral membrane protein
GGC04_11390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GGC04_11395	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GGC04_11400	COG1757	Na H antiporter
GGC04_11425	COG3082	Protein of unknown function (DUF1414)
GGC04_11430	COG3083	sulfuric ester hydrolase activity
GGC04_11465	COG3852	Histidine kinase
GGC04_11495	COG0123	including yeast histone deacetylase and acetoin utilization protein
GGC04_11505	COG1881	PFAM PEBP family protein
GGC04_11515	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GGC04_11520	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GGC04_11540	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GGC04_11545	COG0302	gtp cyclohydrolase
GGC04_11545	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GGC04_11550	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GGC04_11555	COG0302	gtp cyclohydrolase
GGC04_11565	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GGC04_11570	COG0110	maltose O-acetyltransferase activity
GGC04_11620	COG2982	Protein involved in outer membrane biogenesis
GGC04_11625	COG0572	uridine kinase
GGC04_11630	COG0489	protein tyrosine kinase activity
GGC04_11675	COG0517	IMP dehydrogenase activity
GGC04_11685	COG3706	GGDEF domain
GGC04_11690	COG0314	molybdopterin synthase activity
GGC04_11695	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GGC04_11700	COG0315	cyclic pyranopterin monophosphate synthase activity
GGC04_11705	COG0521	Mo-molybdopterin cofactor biosynthetic process
GGC04_11710	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GGC04_11715	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GGC04_11720	COG2198	Histidine kinase
GGC04_11735	COG0556	nucleotide-excision repair
GGC04_11750	COG0739	heme binding
GGC04_11775	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GGC04_11790	COG2204	response regulator
GGC04_11795	COG2885	chlorophyll binding
GGC04_11815	COG1987	bacterial-type flagellum assembly
GGC04_11825	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GGC04_11840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GGC04_11845	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GGC04_11850	COG1516	flagellar protein fliS
GGC04_11865	COG1580	Controls the rotational direction of flagella during chemotaxis
GGC04_11870	COG1191	sigma factor activity
GGC04_11875	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GGC04_11880	COG1360	Flagellar Motor Protein
GGC04_11910	COG1706	bacterial-type flagellum-dependent cell motility
GGC04_11915	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GGC04_11920	COG4786	Flagellar basal body rod
GGC04_11925	COG4787	bacterial-type flagellum-dependent cell motility
GGC04_11930	COG1749	Flagellar hook protein flgE
GGC04_11935	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GGC04_11940	COG1558	bacterial-type flagellum-dependent cell motility
GGC04_11945	COG1815	bacterial-type flagellum-dependent cell motility
GGC04_11965	COG1388	LysM domain
GGC04_11965	COG0741	lytic transglycosylase activity
GGC04_11970	COG4657	Part of a membrane complex involved in electron transport
GGC04_11980	COG4656	Part of a membrane complex involved in electron transport
GGC04_11985	COG4658	electron transport chain
GGC04_12000	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GGC04_12005	COG0346	lactoylglutathione lyase activity
GGC04_12025	COG2056	Na+-H+ antiporter family
GGC04_12035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GGC04_12040	COG2716	regulation of RNA biosynthetic process
GGC04_12045	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GGC04_12050	COG0840	transmembrane signaling receptor activity
GGC04_12065	COG4783	chaperone-mediated protein folding
GGC04_12070	COG1393	Belongs to the ArsC family
GGC04_12090	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GGC04_12105	COG2912	Transglutaminase-like superfamily
GGC04_12115	COG2890	protein-(glutamine-N5) methyltransferase activity
GGC04_12140	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GGC04_12150	COG0012	GTP binding
GGC04_12270	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GGC04_12280	COG3951	Flagellar rod assembly protein muramidase FlgJ
GGC04_12280	COG1705	Flagellar rod assembly protein muramidase FlgJ
GGC04_12285	COG1706	bacterial-type flagellum-dependent cell motility
GGC04_12290	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GGC04_12295	COG4786	Flagellar basal body rod
GGC04_12300	COG4787	bacterial-type flagellum-dependent cell motility
GGC04_12305	COG1749	Flagellar hook protein flgE
GGC04_12310	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GGC04_12315	COG1558	bacterial-type flagellum-dependent cell motility
GGC04_12320	COG1815	bacterial-type flagellum-dependent cell motility
GGC04_12325	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GGC04_12330	COG0784	Response regulator, receiver
GGC04_12330	COG0835	chemotaxis
GGC04_12340	COG2747	anti-sigma28 factor FlgM
GGC04_12380	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GGC04_12390	COG2194	sulfuric ester hydrolase activity
GGC04_12410	COG2885	chlorophyll binding
GGC04_12410	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GGC04_12430	COG2608	mercury ion transmembrane transporter activity
GGC04_12430	COG2217	Heavy metal translocating P-type atpase
GGC04_12450	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GGC04_12460	COG0326	Molecular chaperone. Has ATPase activity
GGC04_12465	COG3710	Transcriptional regulator
GGC04_12485	COG0622	Phosphoesterase
GGC04_12510	COG1090	epimerase
GGC04_12515	COG0300	oxidoreductase activity
GGC04_12520	COG3118	belongs to the thioredoxin family
GGC04_12525	COG0330	HflC and HflK could
GGC04_12555	COG3115	cell septum assembly
GGC04_12560	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GGC04_12565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GGC04_12570	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC04_12580	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GGC04_12585	COG2190	(PTS) system
GGC04_12590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GGC04_12595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GGC04_12605	COG1702	phosphate starvation-inducible protein PhoH
GGC04_12610	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GGC04_12615	COG4535	Mg2 and Co2 transporter CorC
GGC04_12620	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GGC04_12625	COG2888	peptidyl-tyrosine sulfation
GGC04_12630	COG0495	leucyl-tRNA aminoacylation
GGC04_12635	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GGC04_12640	COG1466	dna polymerase III delta subunit
GGC04_12645	COG0799	negative regulation of ribosome biogenesis
GGC04_12650	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GGC04_12655	COG0768	penicillin binding
GGC04_12660	COG0772	Belongs to the SEDS family
GGC04_12665	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GGC04_12670	COG1686	Belongs to the peptidase S11 family
GGC04_12685	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GGC04_12700	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GGC04_12710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGC04_12715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC04_12725	COG0366	Alpha amylase catalytic
GGC04_12730	COG1263	PTS System
GGC04_12730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGC04_12735	COG1609	Transcriptional regulator
GGC04_12745	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GGC04_12750	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GGC04_12755	COG2011	ABC-type metal ion transport system permease component
GGC04_12760	COG1464	Belongs to the NlpA lipoprotein family
GGC04_12775	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GGC04_12785	COG1720	tRNA m6t6A37 methyltransferase activity
GGC04_12795	COG0121	glutamine amidotransferase
GGC04_12800	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GGC04_12805	COG1960	acyl-CoA dehydrogenase activity
GGC04_12815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GGC04_12825	COG2226	methyltransferase
GGC04_12835	COG0741	lytic transglycosylase activity
GGC04_12835	COG1388	LysM domain
GGC04_12850	COG0347	Belongs to the P(II) protein family
GGC04_12865	COG0825	malonyl-CoA metabolic process
GGC04_12870	COG0587	DNA-directed DNA polymerase activity
GGC04_12875	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GGC04_12895	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GGC04_12900	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GGC04_12905	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GGC04_12910	COG0750	zinc metalloprotease
GGC04_12920	COG0575	Belongs to the CDS family
GGC04_12925	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GGC04_12930	COG0233	cytoplasmic translational termination
GGC04_12935	COG0528	UMP kinase activity
GGC04_12945	COG0052	Belongs to the universal ribosomal protein uS2 family
GGC04_12955	COG0024	Methionine aminopeptidase
GGC04_12970	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GGC04_12975	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GGC04_13000	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GGC04_13000	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GGC04_13005	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GGC04_13010	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GGC04_13015	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GGC04_13030	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GGC04_13035	COG2252	PERMEase
GGC04_13040	COG2195	Cleaves the N-terminal amino acid of tripeptides
GGC04_13045	COG4067	protein conserved in archaea
GGC04_13045	COG0189	ligase activity
GGC04_13050	COG0189	ligase activity
GGC04_13060	COG0733	neurotransmitter:sodium symporter activity
GGC04_13075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GGC04_13085	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GGC04_13090	COG3706	GGDEF domain
GGC04_13090	COG0745	RESPONSE REGULATOR receiver
GGC04_13100	COG1477	protein flavinylation
GGC04_13105	COG2871	sodium ion transport
GGC04_13110	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GGC04_13125	COG1805	sodium ion transport
GGC04_13130	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GGC04_13135	COG0271	Belongs to the BolA IbaG family
GGC04_13140	COG2813	Specifically methylates the guanine in position
GGC04_13150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GGC04_13165	COG1595	DNA-templated transcription, initiation
GGC04_13180	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GGC04_13185	COG0693	protein deglycase activity
GGC04_13190	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GGC04_13195	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GGC04_13205	COG0560	Phosphoserine phosphatase
GGC04_13215	COG0813	purine-nucleoside phosphorylase activity
GGC04_13220	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GGC04_13225	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GGC04_13240	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GGC04_13245	COG0084	hydrolase, TatD family'
GGC04_13255	COG3022	response to hydroperoxide
GGC04_13260	COG1115	amino acid carrier protein
GGC04_13295	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GGC04_13325	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GGC04_13330	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GGC04_13340	COG0583	DNA-binding transcription factor activity
GGC04_13345	COG0730	response to heat
GGC04_13350	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GGC04_13355	COG0505	Belongs to the CarA family
GGC04_13365	COG0494	nUDIX hydrolase
GGC04_13370	COG0653	protein targeting
GGC04_13375	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GGC04_13380	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GGC04_13385	COG0849	cell division
GGC04_13390	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GGC04_13405	COG0772	Belongs to the SEDS family
GGC04_13410	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GGC04_13415	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GGC04_13420	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GGC04_13430	COG0768	penicillin binding
GGC04_13435	COG3116	cell division
GGC04_13455	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GGC04_13460	COG3107	peptidoglycan biosynthetic process
GGC04_13470	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GGC04_13480	COG2969	positive regulation of protein catabolic process
GGC04_13485	COG0625	glutathione transferase activity
GGC04_13490	COG2857	Cytochrome c1
GGC04_13495	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GGC04_13500	COG0723	plastoquinol--plastocyanin reductase activity
GGC04_13515	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GGC04_13520	COG3105	Protein conserved in bacteria
GGC04_13525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GGC04_13530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GGC04_13540	COG0187	DNA topoisomerase II activity
GGC04_13545	COG3150	esterase
GGC04_13555	COG3151	Protein conserved in bacteria
GGC04_13560	COG0494	nUDIX hydrolase
GGC04_13565	COG1538	Outer membrane efflux protein
GGC04_13575	COG0784	Response regulator, receiver
GGC04_13575	COG2198	Histidine kinase
GGC04_13575	COG5002	protein histidine kinase activity
GGC04_13580	COG3706	GGDEF domain
GGC04_13580	COG4251	negative regulation of phosphorylation
GGC04_13580	COG5001	Diguanylate cyclase
GGC04_13580	COG2203	Gaf domain
GGC04_13585	COG1242	4 iron, 4 sulfur cluster binding
GGC04_13590	COG0067	glutamate synthase
GGC04_13590	COG0070	glutamate synthase
GGC04_13590	COG0069	glutamate synthase activity
GGC04_13600	COG0067	glutamate synthase
GGC04_13600	COG0070	glutamate synthase
GGC04_13600	COG0069	glutamate synthase activity
GGC04_13605	COG0493	'glutamate synthase
GGC04_13630	COG0195	Participates in both transcription termination and antitermination
GGC04_13635	COG0779	Required for maturation of 30S ribosomal subunits
GGC04_13650	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GGC04_13655	COG3153	acetyltransferase
GGC04_13680	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GGC04_13685	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GGC04_13700	COG0513	Belongs to the DEAD box helicase family
GGC04_13730	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GGC04_13735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GGC04_13740	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GGC04_13745	COG1534	Rna-binding protein
GGC04_13750	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GGC04_13755	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GGC04_13760	COG2027	D-alanyl-D-alanine carboxypeptidase
GGC04_13770	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GGC04_13775	COG0739	heme binding
GGC04_13800	COG0628	permease
GGC04_13805	COG2813	Specifically methylates the guanine in position
GGC04_13815	COG0747	negative chemotaxis
GGC04_13830	COG0444	Belongs to the ABC transporter superfamily
GGC04_13835	COG4608	Belongs to the ABC transporter superfamily
GGC04_13845	COG2971	BadF BadG BcrA BcrD
GGC04_13860	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GGC04_13865	COG3842	ATPase activity
GGC04_13875	COG1840	ABC-type Fe3 transport system, periplasmic component
GGC04_13880	COG0004	ammonium transporteR
GGC04_13895	COG1049	propionate catabolic process, 2-methylcitrate cycle
GGC04_13900	COG1752	Esterase of the alpha-beta hydrolase superfamily
GGC04_13905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GGC04_13910	COG1643	Atp-dependent helicase
GGC04_13920	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GGC04_13935	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GGC04_13950	COG0842	Transport permease protein
GGC04_13955	COG1131	(ABC) transporter
GGC04_13960	COG0659	secondary active sulfate transmembrane transporter activity
GGC04_13965	COG0288	reversible hydration of carbon dioxide
GGC04_13980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GGC04_13985	COG0508	dehydrogenase complex catalyzes the overall conversion of
GGC04_13990	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GGC04_13995	COG2186	Transcriptional regulator
GGC04_14000	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GGC04_14005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GGC04_14015	COG0716	FMN binding
GGC04_14020	COG3023	N-Acetylmuramoyl-L-alanine amidase
GGC04_14025	COG0157	Belongs to the NadC ModD family
GGC04_14030	COG4969	Belongs to the N-Me-Phe pilin family
GGC04_14035	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GGC04_14040	COG1459	type II secretion system
GGC04_14050	COG0237	dephospho-CoA kinase activity
GGC04_14055	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GGC04_14060	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GGC04_14070	COG0336	Belongs to the RNA methyltransferase TrmD family
GGC04_14080	COG0228	four-way junction DNA binding
GGC04_14085	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GGC04_14090	COG4137	Cytochrome C assembly protein
GGC04_14095	COG4536	flavin adenine dinucleotide binding
GGC04_14100	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GGC04_14105	COG4942	peptidase
GGC04_14105	COG1388	LysM domain
GGC04_14115	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GGC04_14120	COG0585	pseudouridine synthase activity
GGC04_14130	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GGC04_14135	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GGC04_14145	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GGC04_14150	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GGC04_14155	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GGC04_14160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GGC04_14165	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GGC04_14170	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GGC04_14175	COG1610	YqeY-like protein
GGC04_14180	COG0358	DNA primase activity
GGC04_14185	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GGC04_14195	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GGC04_14200	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GGC04_14205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GGC04_14210	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GGC04_14225	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GGC04_14230	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GGC04_14235	COG3610	response to peptide
GGC04_14240	COG2966	Psort location CytoplasmicMembrane, score
GGC04_14245	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GGC04_14250	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GGC04_14255	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GGC04_14260	COG0142	geranyltranstransferase activity
GGC04_14270	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GGC04_14280	COG2213	PTS system mannitol-specific
GGC04_14280	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC04_14290	COG3722	fumarate hydratase activity
GGC04_14295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGC04_14300	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GGC04_14305	COG1349	DNA-binding transcription factor activity
GGC04_14310	COG0469	pyruvate kinase activity
GGC04_14320	COG3706	GGDEF domain
GGC04_14330	COG0583	DNA-binding transcription factor activity
GGC04_14345	COG0668	transmembrane transport
GGC04_14350	COG0191	fructose-bisphosphate aldolase activity
GGC04_14365	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GGC04_14370	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GGC04_14380	COG3091	SprT-like family
GGC04_14385	COG2356	endonuclease I
GGC04_14390	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GGC04_14395	COG0189	ligase activity
GGC04_14405	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GGC04_14420	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GGC04_14425	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GGC04_14430	COG0762	integral membrane protein
GGC04_14580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GGC04_14585	COG2066	Belongs to the glutaminase family
GGC04_14590	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GGC04_14600	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GGC04_14655	COG0312	modulator of DNA gyrase
GGC04_14660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GGC04_14665	COG3164	Protein of unknown function
GGC04_14670	COG1530	ribonuclease E activity
GGC04_14675	COG0424	maF-like protein
GGC04_14680	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GGC04_14685	COG1792	Involved in formation and maintenance of cell shape
GGC04_14690	COG1077	Cell shape determining protein MreB Mrl
GGC04_14740	COG1459	type II secretion system
GGC04_14745	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GGC04_14755	COG3409	Peptidoglycan-binding domain 1 protein
GGC04_14755	COG3267	Type II secretory pathway component ExeA
GGC04_14780	COG2200	EAL domain
GGC04_14780	COG2199	diguanylate cyclase activity
GGC04_14785	COG0629	single-stranded DNA binding
GGC04_14800	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GGC04_14810	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GGC04_14815	COG0527	aspartate kinase activity
GGC04_14820	COG0312	modulator of DNA gyrase
GGC04_14825	COG3028	Belongs to the UPF0307 family
GGC04_14830	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GGC04_14835	COG1178	ABC-type Fe3 transport system permease component
GGC04_14840	COG4143	(ABC) transporter
GGC04_14845	COG0163	prenyltransferase activity
GGC04_14850	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GGC04_14865	COG2105	PFAM AIG2 family protein
GGC04_14870	COG2911	Protein conserved in bacteria
GGC04_14875	COG0729	surface antigen
GGC04_14880	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GGC04_14890	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GGC04_14900	COG1136	(ABC) transporter
GGC04_14930	COG0432	Pfam Uncharacterised protein family UPF0047
GGC04_15025	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GGC04_15030	COG0305	Participates in initiation and elongation during chromosome replication
GGC04_15050	COG0360	Binds together with S18 to 16S ribosomal RNA
GGC04_15060	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GGC04_15065	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GGC04_15070	COG0049	tRNA binding
GGC04_15080	COG2168	tRNA wobble position uridine thiolation
GGC04_15085	COG2923	Belongs to the DsrF TusC family
GGC04_15095	COG2964	Protein conserved in bacteria
GGC04_15100	COG0545	Peptidyl-prolyl cis-trans isomerase
GGC04_15115	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GGC04_15120	COG0330	HflC and HflK could
GGC04_15125	COG0330	HflC and HflK could
GGC04_15130	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GGC04_15145	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GGC04_15155	COG0802	atpase or kinase
GGC04_15160	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GGC04_15215	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GGC04_15220	COG1162	GTPase activity
GGC04_15225	COG0688	phosphatidylethanolamine metabolic process
GGC04_15230	COG0471	metal ion transport
GGC04_15230	COG0490	domain, Protein
GGC04_15235	COG0840	transmembrane signaling receptor activity
GGC04_15245	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GGC04_15250	COG4942	peptidase
GGC04_15270	COG2816	NAD+ diphosphatase activity
GGC04_15275	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GGC04_15285	COG0085	RNA polymerase activity
GGC04_15295	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GGC04_15310	COG0250	Participates in transcription elongation, termination and antitermination
GGC04_15315	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GGC04_15325	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GGC04_15350	COG1072	(Pantothenic acid kinase))
GGC04_15365	COG0149	triose-phosphate isomerase activity
GGC04_15370	COG0534	Mate efflux family protein
GGC04_15375	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GGC04_15380	COG1575	Belongs to the MenA family. Type 1 subfamily
GGC04_15385	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GGC04_15390	COG1509	lysine 2,3-aminomutase activity
GGC04_15400	COG1285	pathogenesis
GGC04_15405	COG0205	6-phosphofructokinase activity
GGC04_15415	COG3678	ATP-independent chaperone mediated protein folding
GGC04_15420	COG0745	RESPONSE REGULATOR receiver
GGC04_15425	COG2205	protein histidine kinase activity
GGC04_15430	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GGC04_15435	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GGC04_15440	COG0180	Tryptophanyl-tRNA synthetase
GGC04_15445	COG0546	phosphoglycolate phosphatase activity
GGC04_15450	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GGC04_15455	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GGC04_15500	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GGC04_15510	COG0678	peroxiredoxin activity
GGC04_15510	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GGC04_15520	COG0251	oxidation-reduction process
GGC04_15525	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GGC04_15525	COG0165	Argininosuccinate lyase
GGC04_15530	COG0137	argininosuccinate synthase activity
GGC04_15540	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GGC04_15640	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GGC04_15650	COG4206	TonB-dependent receptor
GGC04_15675	COG0534	Mate efflux family protein
GGC04_15685	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GGC04_15690	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GGC04_15700	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GGC04_15705	COG3161	chorismate lyase activity
GGC04_15710	COG1580	Controls the rotational direction of flagella during chemotaxis
GGC04_15720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GGC04_15725	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GGC04_15730	COG2177	Part of the ABC transporter FtsEX involved in
GGC04_15735	COG2884	Cell division ATP-binding protein ftsE
GGC04_15740	COG0552	protein localization to endoplasmic reticulum
GGC04_15745	COG0742	ribosomal rna small subunit methyltransferase
GGC04_15755	COG2095	MarC family integral membrane protein
GGC04_15800	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GGC04_15805	COG0640	Transcriptional regulator
GGC04_15810	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GGC04_15815	COG1280	lysine exporter protein (LysE YggA)
GGC04_15825	COG0561	phosphatase activity
GGC04_15845	COG2200	EAL domain
GGC04_15845	COG2199	diguanylate cyclase activity
GGC04_15845	COG3287	FIST C domain
GGC04_15850	COG1011	Hydrolase
GGC04_15855	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GGC04_15865	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GGC04_15870	COG0019	diaminopimelate decarboxylase activity
GGC04_15875	COG1965	Belongs to the frataxin family
GGC04_15880	COG3072	Adenylate cyclase
GGC04_15890	COG1587	Uroporphyrinogen-III synthase
GGC04_15895	COG2959	enzyme of heme biosynthesis
GGC04_15900	COG3071	HemY protein
GGC04_15960	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GGC04_15970	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GGC04_15975	COG3118	belongs to the thioredoxin family
GGC04_15985	COG0248	Ppx GppA phosphatase
GGC04_15990	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GGC04_16000	COG0514	ATP-dependent DNA helicase (RecQ)
GGC04_16005	COG2962	Rard protein
GGC04_16015	COG1280	lysine exporter protein (LysE YggA)
GGC04_16020	COG0405	Gamma-glutamyltransferase
GGC04_16040	COG0210	DNA helicase
GGC04_16055	COG3220	belongs to the UPF0276 family
GGC04_16075	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GGC04_16080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GGC04_16095	COG1773	rubredoxin
GGC04_16110	COG0367	asparagine synthase
GGC04_16115	COG0477	Major facilitator Superfamily
GGC04_16140	COG0745	RESPONSE REGULATOR receiver
GGC04_16155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GGC04_16165	COG0747	negative chemotaxis
GGC04_16200	COG1309	transcriptional regulator
GGC04_16205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC04_16210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGC04_16215	COG2960	long-chain fatty acid transporting porin activity
GGC04_16225	COG0583	DNA-binding transcription factor activity
GGC04_16230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GGC04_16255	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GGC04_16265	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GGC04_16265	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GGC04_16280	COG1943	Transposase
GGC04_16290	COG0084	hydrolase, TatD family'
GGC04_16295	COG0805	protein transport
GGC04_16325	COG1322	Protein conserved in bacteria
GGC04_16335	COG1639	'signal transduction protein
GGC04_16365	COG2081	HI0933 family
GGC04_16375	COG1528	Iron-storage protein
GGC04_16380	COG0589	response to stress
GGC04_16385	COG0697	spore germination
GGC04_16395	COG0742	ribosomal rna small subunit methyltransferase
GGC04_16400	COG5002	protein histidine kinase activity
GGC04_16400	COG5001	Diguanylate cyclase
GGC04_16405	COG1522	sequence-specific DNA binding
GGC04_16410	COG1943	Transposase
GGC04_16430	COG0006	proline dipeptidase activity
GGC04_16430	COG0006	proline dipeptidase activity
GGC04_16440	COG2022	thiamine diphosphate biosynthetic process
GGC04_16450	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GGC04_16455	COG0352	thiamine-phosphate diphosphorylase activity
GGC04_16470	COG2132	Multicopper oxidase
GGC04_16525	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GGC04_16530	COG1739	Uncharacterized protein family UPF0029
GGC04_16540	COG0183	Belongs to the thiolase family
GGC04_16545	COG3706	GGDEF domain
GGC04_16550	COG0583	DNA-binding transcription factor activity
GGC04_16555	COG2814	Major facilitator Superfamily
GGC04_16565	COG0765	amino acid transport
GGC04_16575	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GGC04_16580	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GGC04_16585	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GGC04_16590	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GGC04_16595	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GGC04_16615	COG3312	ion transport
GGC04_16620	COG1475	DNA binding
GGC04_16625	COG1192	Involved in chromosome partitioning
GGC04_16635	COG0445	tRNA wobble uridine modification
GGC04_16640	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GGC04_16645	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GGC04_16650	COG0706	membrane insertase activity
GGC04_16665	COG1126	abc transporter atp-binding protein
GGC04_16680	COG0840	transmembrane signaling receptor activity
GGC04_16685	COG0366	Alpha amylase catalytic
GGC04_16695	COG2354	Protein conserved in bacteria
GGC04_16720	COG1349	DNA-binding transcription factor activity
GGC04_16730	COG0633	Ferredoxin
GGC04_16730	COG3217	Mosc domain protein beta barrel domain protein
GGC04_16730	COG0633	Ferredoxin
GGC04_16730	COG3217	Mosc domain protein beta barrel domain protein
GGC04_16755	COG2197	response regulator
GGC04_16760	COG3851	Histidine kinase
GGC04_16765	COG2271	Major facilitator Superfamily
GGC04_16775	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GGC04_16785	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GGC04_16790	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GGC04_16795	COG0363	glucosamine-6-phosphate deaminase activity
GGC04_16800	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GGC04_16825	COG3284	Transcriptional regulator
GGC04_16830	COG1012	belongs to the aldehyde dehydrogenase family
GGC04_16860	COG0579	oxidoreductase
GGC04_16870	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GGC04_16880	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GGC04_16885	COG0840	transmembrane signaling receptor activity
GGC04_16910	COG2814	Major facilitator Superfamily
GGC04_16915	COG0583	DNA-binding transcription factor activity
GGC04_16940	COG0564	pseudouridine synthase activity
GGC04_16955	COG2356	endonuclease I
GGC04_16970	COG0251	oxidation-reduction process
GGC04_17010	COG0110	maltose O-acetyltransferase activity
GGC04_17020	COG1621	beta-fructofuranosidase activity
GGC04_17035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGC04_17040	COG1554	hydrolase, family 65, central catalytic
GGC04_17045	COG0395	ABC-type sugar transport system, permease component
GGC04_17065	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GGC04_17075	COG0573	inorganic phosphate transmembrane transporter activity
GGC04_17115	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GGC04_17125	COG0513	Belongs to the DEAD box helicase family
GGC04_17145	COG3706	GGDEF domain
GGC04_17150	COG1309	transcriptional regulator
GGC04_17155	COG2130	NADP-dependent
GGC04_17170	COG2084	Dehydrogenase
GGC04_17190	COG0366	Alpha amylase catalytic
GGC04_17200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGC04_17205	COG0625	glutathione transferase activity
GGC04_17210	COG0346	lactoylglutathione lyase activity
GGC04_17250	COG1131	(ABC) transporter
GGC04_17255	COG0842	Transport permease protein
GGC04_17290	COG5002	protein histidine kinase activity
GGC04_17295	COG0745	RESPONSE REGULATOR receiver
GGC04_17315	COG1309	transcriptional regulator
GGC04_17325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGC04_17350	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GGC04_17370	COG1805	sodium ion transport
GGC04_17375	COG1271	oxidase subunit
GGC04_17380	COG1294	oxidase, subunit
GGC04_17385	COG1357	PFAM Pentapeptide repeats (8 copies)
GGC04_17410	COG1522	sequence-specific DNA binding
GGC04_17420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGC04_17440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGC04_17445	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GGC04_17445	COG2207	Transcriptional regulator
GGC04_17455	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GGC04_17455	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GGC04_17480	COG0697	spore germination
GGC04_17500	COG0415	Belongs to the DNA photolyase family
GGC04_17510	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GGC04_17540	COG0840	transmembrane signaling receptor activity
GGC04_17570	COG0840	transmembrane signaling receptor activity
GGC04_17580	COG4580	involved in the transport of maltose and maltodextrins
GGC04_17595	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GGC04_17605	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GGC04_17630	COG0583	DNA-binding transcription factor activity
GGC04_17640	COG1132	(ABC) transporter
GGC04_17645	COG0589	response to stress
GGC04_17655	COG2111	Na H antiporter
GGC04_17655	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GGC04_17660	COG1006	Multisubunit Na H antiporter MnhC subunit
GGC04_17675	COG2212	antiporter activity
GGC04_17680	COG1320	monovalent cation:proton antiporter activity
GGC04_17685	COG4191	Histidine kinase
GGC04_17685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC04_17715	COG0488	(ABC) transporter
GGC04_17720	COG0673	inositol 2-dehydrogenase activity
GGC04_17725	COG5553	Cysteine dioxygenase type I
GGC04_17730	COG0300	oxidoreductase activity
GGC04_17755	COG3047	cAMP biosynthetic process
GGC04_17760	COG0739	heme binding
GGC04_17785	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GGC04_17790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGC04_17795	COG0446	pyridine nucleotide-disulphide oxidoreductase
GGC04_17800	COG3383	formate dehydrogenase (NAD+) activity
GGC04_17810	COG0004	ammonium transporteR
GGC04_17840	COG1234	tRNA 3'-trailer cleavage
GGC04_17845	COG0583	DNA-binding transcription factor activity
GGC04_17865	COG3304	Inner membrane component domain
GGC04_17870	COG2329	Antibiotic biosynthesis monooxygenase
GGC04_17880	COG3046	protein related to deoxyribodipyrimidine photolyase
GGC04_17885	COG0415	Belongs to the DNA photolyase family
GGC04_17910	COG3604	Transcriptional regulator
GGC04_17925	COG0583	DNA-binding transcription factor activity
GGC04_17935	COG1151	hydroxylamine reductase activity
GGC04_17940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GGC04_17945	COG0583	DNA-binding transcription factor activity
GGC04_17990	COG0745	RESPONSE REGULATOR receiver
GGC04_18010	COG1288	antiporter activity
GGC04_18015	COG3608	succinylglutamate desuccinylase aspartoacylase
GGC04_18045	COG1522	sequence-specific DNA binding
GGC04_18055	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GGC04_18060	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GGC04_18065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GGC04_18095	COG0840	transmembrane signaling receptor activity
GGC04_18100	COG0454	-acetyltransferase
GGC04_18115	COG0363	glucosamine-6-phosphate deaminase activity
GGC04_18120	COG4720	Psort location CytoplasmicMembrane, score
GGC04_18125	COG1122	ATPase activity
GGC04_18145	COG1162	GTPase activity
GGC04_18150	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GGC04_18170	COG0581	inorganic phosphate transmembrane transporter activity
GGC04_18175	COG0573	inorganic phosphate transmembrane transporter activity
GGC04_18180	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GGC04_18185	COG0840	transmembrane signaling receptor activity
GGC04_18195	COG4221	oxidoreductase activity
GGC04_18215	COG1477	protein flavinylation
GGC04_18270	COG2894	cell division
GGC04_18280	COG4964	Belongs to the GSP D family
GGC04_18315	COG2095	MarC family integral membrane protein
GGC04_18335	COG4176	ABC-type proline glycine betaine transport system permease component
GGC04_18340	COG3448	diguanylate cyclase activity
GGC04_18340	COG4175	Glycine betaine
GGC04_18390	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GGC04_18390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GGC04_18405	COG0590	tRNA wobble adenosine to inosine editing
GGC04_18410	COG2076	Multidrug Resistance protein
GGC04_18415	COG2076	Multidrug Resistance protein
GGC04_18420	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GGC04_18425	COG1960	acyl-CoA dehydrogenase activity
GGC04_18430	COG0662	Cupin 2, conserved barrel domain protein
GGC04_18440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GGC04_18450	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GGC04_18475	COG4264	IucA IucC family
GGC04_18490	COG1120	ATPase activity
GGC04_18495	COG2814	Major facilitator Superfamily
GGC04_18505	COG4968	Prepilin-type N-terminal cleavage methylation domain
GGC04_18510	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC04_18510	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC04_18510	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC04_18520	COG0383	alpha-mannosidase activity
GGC04_18525	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GGC04_18525	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC04_18525	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC04_18550	COG0583	DNA-binding transcription factor activity
GGC04_18560	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_18565	COG1414	Transcriptional regulator
GGC04_18590	COG0702	epimerase
GGC04_18640	COG1733	regulation of RNA biosynthetic process
GGC04_18660	COG1917	Cupin 2, conserved barrel domain protein
GGC04_18660	COG4977	sequence-specific DNA binding
GGC04_18665	COG4771	TonB-dependent receptor
GGC04_18670	COG2814	Major facilitator Superfamily
GGC04_18675	COG3433	isochorismatase activity
GGC04_18675	COG2226	methyltransferase
GGC04_18675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GGC04_18690	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GGC04_18695	COG1169	isochorismate synthase
GGC04_18700	COG1021	2,3-dihydroxybenzoate-AMP ligase
GGC04_18705	COG1132	(ABC) transporter
GGC04_18710	COG1132	(ABC) transporter
GGC04_18735	COG0024	Methionine aminopeptidase
GGC04_18750	COG0561	phosphatase activity
GGC04_18800	COG0300	oxidoreductase activity
GGC04_18810	COG0583	DNA-binding transcription factor activity
GGC04_18820	COG2249	NAD(P)H dehydrogenase (quinone) activity
GGC04_18870	COG1619	proteins homologs of microcin C7 resistance protein MccF
GGC04_18885	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GGC04_18890	COG1640	4-alpha-glucanotransferase
GGC04_18895	COG0058	SHG alpha-glucan phosphorylase activity
GGC04_18900	COG2909	trisaccharide binding
GGC04_18945	COG2207	Transcriptional regulator
GGC04_18950	COG1335	isochorismatase
GGC04_18955	COG1404	Belongs to the peptidase S8 family
GGC04_18960	COG0402	S-adenosylhomocysteine deaminase activity
GGC04_18990	COG3795	YCII-related domain
GGC04_19015	COG2186	Transcriptional regulator
GGC04_19025	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GGC04_19035	COG0402	S-adenosylhomocysteine deaminase activity
GGC04_19040	COG2226	methyltransferase
GGC04_19045	COG5002	protein histidine kinase activity
GGC04_19045	COG2205	protein histidine kinase activity
GGC04_19045	COG0784	Response regulator, receiver
GGC04_19055	COG1522	sequence-specific DNA binding
GGC04_19065	COG0840	transmembrane signaling receptor activity
GGC04_19085	COG4266	Belongs to the allantoicase family
GGC04_19105	COG2252	PERMEase
GGC04_19120	COG0596	Alpha beta hydrolase
GGC04_19125	COG3214	Protein conserved in bacteria
GGC04_19150	COG0583	DNA-binding transcription factor activity
GGC04_19175	COG3179	chitinase
GGC04_19190	COG0109	protoheme IX farnesyltransferase activity
GGC04_19195	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GGC04_19200	COG1845	cytochrome c oxidase, subunit III
GGC04_19205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GGC04_19210	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GGC04_19220	COG2706	6-phosphogluconolactonase activity
GGC04_19230	COG0800	Aldolase
GGC04_19235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC04_19240	COG4145	pantothenate transmembrane transporter activity
GGC04_19250	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GGC04_19265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC04_19270	COG0840	transmembrane signaling receptor activity
GGC04_19315	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GGC04_19320	COG0804	urea catabolic process
GGC04_19325	COG0832	Belongs to the urease beta subunit family
GGC04_19330	COG0831	urea catabolic process
GGC04_19355	COG0559	Belongs to the binding-protein-dependent transport system permease family
GGC04_19370	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GGC04_19395	COG2084	Dehydrogenase
GGC04_19400	COG3622	Belongs to the hyi family
GGC04_19405	COG3960	tartronate-semialdehyde synthase activity
GGC04_19410	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GGC04_19420	COG0583	DNA-binding transcription factor activity
GGC04_19425	COG1288	antiporter activity
GGC04_19455	COG1846	Transcriptional regulator
GGC04_19460	COG0697	spore germination
GGC04_19465	COG3300	MHYT domain
GGC04_19465	COG5001	Diguanylate cyclase
GGC04_19480	COG1051	belongs to the nudix hydrolase family
GGC04_19485	COG0583	DNA-binding transcription factor activity
GGC04_19505	COG1733	regulation of RNA biosynthetic process
GGC04_19510	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_19520	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_19555	COG0444	Belongs to the ABC transporter superfamily
GGC04_19560	COG4608	Belongs to the ABC transporter superfamily
GGC04_19590	COG1444	tRNA N-acetyltransferase activity
GGC04_19595	COG0840	transmembrane signaling receptor activity
GGC04_19605	COG0745	RESPONSE REGULATOR receiver
GGC04_19620	COG0835	chemotaxis
GGC04_19625	COG0840	transmembrane signaling receptor activity
GGC04_19630	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GGC04_19655	COG0745	RESPONSE REGULATOR receiver
GGC04_19655	COG3706	GGDEF domain
GGC04_19675	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GGC04_19735	COG0583	DNA-binding transcription factor activity
GGC04_19740	COG1175	transmembrane transport
GGC04_19760	COG0546	phosphoglycolate phosphatase activity
GGC04_19765	COG3842	ATPase activity
GGC04_19775	COG2723	6-phospho-beta-galactosidase activity
GGC04_19780	COG0768	penicillin binding
GGC04_19785	COG0840	transmembrane signaling receptor activity
GGC04_19810	COG0583	DNA-binding transcription factor activity
GGC04_19830	COG0656	L-ascorbic acid biosynthetic process
GGC04_19835	COG0351	phosphomethylpyrimidine kinase
GGC04_19840	COG1116	anion transmembrane transporter activity
GGC04_19845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GGC04_19850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GGC04_19855	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GGC04_19875	COG3708	Transcriptional regulator
GGC04_19875	COG2207	Transcriptional regulator
GGC04_19885	COG0671	phosphoesterase, PA-phosphatase related
GGC04_19895	COG0438	transferase activity, transferring glycosyl groups
GGC04_19905	COG1940	carbohydrate kinase activity
GGC04_19920	COG1175	transmembrane transport
GGC04_19930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GGC04_19970	COG1063	alcohol dehydrogenase
GGC04_19980	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GGC04_19980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GGC04_19990	COG0251	oxidation-reduction process
GGC04_19995	COG0697	spore germination
GGC04_20010	COG1595	DNA-templated transcription, initiation
GGC04_20050	COG0471	metal ion transport
GGC04_20055	COG2205	protein histidine kinase activity
GGC04_20060	COG0745	RESPONSE REGULATOR receiver
GGC04_20085	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GGC04_20095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC04_20100	COG0745	RESPONSE REGULATOR receiver
GGC04_20105	COG3850	Histidine kinase
GGC04_20105	COG2205	protein histidine kinase activity
GGC04_20105	COG4999	Histidine kinase
GGC04_20105	COG3437	response regulator, receiver
GGC04_20120	COG5002	protein histidine kinase activity
GGC04_20125	COG0745	RESPONSE REGULATOR receiver
GGC04_20135	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GGC04_20150	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GGC04_20155	COG3366	ferrous iron transmembrane transporter activity
GGC04_20160	COG0700	Nucleoside recognition
GGC04_20170	COG2207	Transcriptional regulator
GGC04_20185	COG1404	Belongs to the peptidase S8 family
GGC04_20200	COG1301	dicarboxylic acid transport
GGC04_20355	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GGC04_20380	COG0346	lactoylglutathione lyase activity
GGC04_20390	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GGC04_20400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GGC04_20435	COG2814	Major facilitator Superfamily
GGC04_20440	COG0583	DNA-binding transcription factor activity
GGC04_20445	COG0393	Putative heavy-metal-binding
GGC04_20450	COG1671	Belongs to the UPF0178 family
GGC04_20465	COG1999	signal sequence binding
GGC04_20475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GGC04_20480	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GGC04_20485	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GGC04_20490	COG3033	Beta-eliminating lyase
GGC04_20520	COG0259	pyridoxamine-phosphate oxidase activity
GGC04_20530	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GGC04_20575	COG1132	(ABC) transporter
GGC04_20585	COG0583	DNA-binding transcription factor activity
GGC04_20600	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GGC04_20615	COG0786	glutamate:sodium symporter activity
GGC04_20620	COG1566	PFAM secretion protein HlyD family protein
GGC04_20635	COG3706	GGDEF domain
GGC04_20650	COG0813	purine-nucleoside phosphorylase activity
GGC04_20655	COG3272	Protein of unknown function (DUF1722)
GGC04_20660	COG0789	Transcriptional regulator
GGC04_20665	COG0415	Belongs to the DNA photolyase family
GGC04_20670	COG1376	ErfK ybiS ycfS ynhG family protein
GGC04_20670	COG1388	LysM domain
GGC04_20680	COG0513	Belongs to the DEAD box helicase family
GGC04_20685	COG3291	Pkd domain containing protein
GGC04_20690	COG3568	Endonuclease Exonuclease Phosphatase
GGC04_20725	COG0006	proline dipeptidase activity
GGC04_20740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GGC04_20745	COG0601	transmembrane transport
GGC04_20760	COG2186	Transcriptional regulator
GGC04_20770	COG3938	Belongs to the proline racemase family
GGC04_20785	COG2423	ornithine cyclodeaminase activity
GGC04_20790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GGC04_20795	COG3842	ATPase activity
GGC04_20800	COG1176	ABC-type spermidine putrescine transport system, permease component I
GGC04_20805	COG1177	transmembrane transport
GGC04_20815	COG1280	lysine exporter protein (LysE YggA)
GGC04_20825	COG1846	Transcriptional regulator
GGC04_20865	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GGC04_20870	COG2988	succinylglutamate desuccinylase activity
GGC04_20875	COG0523	cobalamin synthesis protein
GGC04_20885	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GGC04_20940	COG0583	DNA-binding transcription factor activity
GGC04_20945	COG1280	lysine exporter protein (LysE YggA)
GGC04_20985	COG1253	flavin adenine dinucleotide binding
GGC04_21020	COG0583	DNA-binding transcription factor activity
GGC04_21025	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GGC04_21030	COG1686	Belongs to the peptidase S11 family
GGC04_21035	COG2814	Major facilitator Superfamily
GGC04_21045	COG1741	Belongs to the pirin family
GGC04_21060	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GGC04_21085	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GGC04_21125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GGC04_21130	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GGC04_21135	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GGC04_21140	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GGC04_21165	COG1612	heme a metabolic process
GGC04_21170	COG0109	protoheme IX farnesyltransferase activity
GGC04_21175	COG0765	amino acid transport
GGC04_21180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC04_21185	COG0765	amino acid transport
GGC04_21190	COG1126	abc transporter atp-binding protein
GGC04_21195	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GGC04_21205	COG0366	Alpha amylase catalytic
GGC04_21215	COG4989	oxidoreductase activity
GGC04_21220	COG5001	Diguanylate cyclase
GGC04_21220	COG3706	GGDEF domain
GGC04_21220	COG4251	negative regulation of phosphorylation
GGC04_21220	COG2203	Gaf domain
GGC04_21230	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GGC04_21235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GGC04_21240	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GGC04_21245	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GGC04_21250	COG0438	transferase activity, transferring glycosyl groups
GGC04_21265	COG1045	serine acetyltransferase
GGC04_21275	COG0438	transferase activity, transferring glycosyl groups
GGC04_21275	COG0297	glycogen (starch) synthase activity
GGC04_21285	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GGC04_21335	COG5001	Diguanylate cyclase
GGC04_21340	COG0583	DNA-binding transcription factor activity
GGC04_21345	COG2814	Major facilitator Superfamily
GGC04_21360	COG0697	spore germination
GGC04_21370	COG0534	Mate efflux family protein
GGC04_21380	COG2249	NAD(P)H dehydrogenase (quinone) activity
GGC04_21385	COG0546	phosphoglycolate phosphatase activity
GGC04_21395	COG3604	Transcriptional regulator
GGC04_21400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GGC04_21400	COG1017	nitric oxide dioxygenase activity
GGC04_21415	COG1278	Cold shock
GGC04_21420	COG3036	rescue of stalled ribosome
GGC04_21435	COG1686	Belongs to the peptidase S11 family
GGC04_21450	COG3530	Putative quorum-sensing-regulated virulence factor
GGC04_21470	COG1012	belongs to the aldehyde dehydrogenase family
GGC04_21485	COG1136	(ABC) transporter
GGC04_21505	COG3275	phosphorelay sensor kinase activity
GGC04_21510	COG3279	Response regulator of the LytR AlgR family
GGC04_21540	COG0366	Alpha amylase catalytic
GGC04_21560	COG0747	negative chemotaxis
GGC04_21565	COG4608	Belongs to the ABC transporter superfamily
GGC04_21570	COG0444	Belongs to the ABC transporter superfamily
GGC04_21575	COG0534	Mate efflux family protein
GGC04_21590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GGC04_21605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GGC04_21620	COG2130	NADP-dependent
GGC04_21635	COG0745	RESPONSE REGULATOR receiver
GGC04_21640	COG0642	Histidine kinase
GGC04_21650	COG3706	GGDEF domain
GGC04_21660	COG5001	Diguanylate cyclase
GGC04_21665	COG1396	sequence-specific DNA binding
GGC04_21670	COG4948	Mandelate Racemase Muconate Lactonizing
GGC04_21680	COG0583	DNA-binding transcription factor activity
GGC04_21685	COG0443	Heat shock 70 kDa protein
GGC04_21720	COG1280	lysine exporter protein (LysE YggA)
GGC04_21735	COG4232	protein-disulfide reductase activity
GGC04_21740	COG3118	belongs to the thioredoxin family
GGC04_21780	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GGC04_21800	COG0668	transmembrane transport
GGC04_21810	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GGC04_21830	COG0583	DNA-binding transcription factor activity
GGC04_21855	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GGC04_21865	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GGC04_21870	COG3265	gluconokinase activity
GGC04_21875	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GGC04_21880	COG1609	Transcriptional regulator
GGC04_21905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GGC04_21910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GGC04_21915	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GGC04_21920	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GGC04_21950	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GGC04_21955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GGC04_21975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGC04_22000	COG0004	ammonium transporteR
GGC04_22015	COG3469	chitinase activity
GGC04_22025	COG1869	D-ribose catabolic process
GGC04_22030	COG1129	ABC transporter
GGC04_22035	COG1172	Belongs to the binding-protein-dependent transport system permease family
GGC04_22040	COG1879	ABC-type sugar transport system periplasmic component
GGC04_22045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC04_22050	COG1609	Transcriptional regulator
GGC04_22055	COG0784	Response regulator, receiver
GGC04_22055	COG3437	response regulator, receiver
GGC04_22060	COG4191	Histidine kinase
GGC04_22060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC04_22070	COG0513	Belongs to the DEAD box helicase family
GGC04_22080	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GGC04_22090	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GGC04_22105	COG0739	heme binding
GGC04_22115	COG2814	Major facilitator Superfamily
GGC04_22120	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GGC04_22125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GGC04_22135	COG0848	biopolymer transport protein
GGC04_22140	COG0811	peptide transport
GGC04_22145	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GGC04_22155	COG3721	Heme iron utilization protein
GGC04_22160	COG0748	coenzyme F420 binding
GGC04_22165	COG2096	Adenosyltransferase
GGC04_22170	COG3842	ATPase activity
GGC04_22180	COG1175	transmembrane transport
GGC04_22195	COG1943	Transposase
GGC04_22210	COG4533	DNA binding
GGC04_22250	COG5002	protein histidine kinase activity
GGC04_22250	COG0784	Response regulator, receiver
GGC04_22250	COG2205	protein histidine kinase activity
GGC04_22265	COG0861	Integral membrane protein TerC family
GGC04_22270	COG0402	S-adenosylhomocysteine deaminase activity
GGC04_22275	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GGC04_22285	COG1566	PFAM secretion protein HlyD family protein
GGC04_22310	COG0745	RESPONSE REGULATOR receiver
GGC04_22315	COG2205	protein histidine kinase activity
GGC04_22335	COG0531	amino acid
GGC04_22355	COG0673	inositol 2-dehydrogenase activity
GGC04_22360	COG1765	OsmC-like protein
GGC04_22365	COG0110	maltose O-acetyltransferase activity
GGC04_22390	COG2304	oxidoreductase activity
GGC04_22395	COG2304	oxidoreductase activity
GGC04_22410	COG0714	Associated with various cellular activities
GGC04_22425	COG0583	DNA-binding transcription factor activity
GGC04_22430	COG0667	Aldo Keto reductase
GGC04_22445	COG2205	protein histidine kinase activity
GGC04_22450	COG0745	RESPONSE REGULATOR receiver
GGC04_22465	COG0745	RESPONSE REGULATOR receiver
GGC04_22470	COG2205	protein histidine kinase activity
GGC04_22475	COG4452	Inner membrane protein CreD
GGC04_22485	COG0346	lactoylglutathione lyase activity
GGC04_22510	COG2200	EAL domain
GGC04_22510	COG2199	diguanylate cyclase activity
GGC04_22510	COG2202	Pas domain
GGC04_22515	COG0156	8-amino-7-oxononanoate synthase activity
GGC04_22520	COG1063	alcohol dehydrogenase
GGC04_22550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GGC04_22580	COG0798	PFAM Bile acid sodium symporter
GGC04_22590	COG0612	Peptidase, M16
GGC04_22595	COG0784	Response regulator, receiver
GGC04_22595	COG2205	protein histidine kinase activity
GGC04_22600	COG2205	protein histidine kinase activity
GGC04_22600	COG0784	Response regulator, receiver
GGC04_22620	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GGC04_22625	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GGC04_22630	COG3186	Phenylalanine-4-hydroxylase
GGC04_22675	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GGC04_22680	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GGC04_22725	COG1454	alcohol dehydrogenase
GGC04_22730	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GGC04_22745	COG1011	Hydrolase
GGC04_22750	COG2378	regulation of single-species biofilm formation
GGC04_22775	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GGC04_22780	COG1840	ABC-type Fe3 transport system, periplasmic component
GGC04_22790	COG3842	ATPase activity
GGC04_22820	COG2866	Carboxypeptidase
GGC04_22825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GGC04_22830	COG0583	DNA-binding transcription factor activity
GGC04_22835	COG1760	l-serine dehydratase
GGC04_22860	COG3706	GGDEF domain
GGC04_22865	COG0784	Response regulator, receiver
GGC04_22865	COG0835	chemotaxis
GGC04_22870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GGC04_22885	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_22895	COG0494	nUDIX hydrolase
GGC04_22900	COG0714	Associated with various cellular activities
GGC04_22905	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GGC04_22910	COG2814	Major facilitator Superfamily
GGC04_22930	COG3706	GGDEF domain
GGC04_22935	COG1846	Transcriptional regulator
GGC04_22940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GGC04_22945	COG2176	DNA-directed DNA polymerase activity
GGC04_22955	COG0789	Transcriptional regulator
GGC04_22965	COG5001	Diguanylate cyclase
GGC04_22965	COG3300	MHYT domain
GGC04_22970	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GGC04_22975	COG0583	DNA-binding transcription factor activity
GGC04_23000	COG1858	cytochrome C peroxidase
GGC04_23020	COG1716	ATPase activity
GGC04_23020	COG5001	Diguanylate cyclase
GGC04_23040	COG2910	NAD(P)H-binding
GGC04_23045	COG0583	DNA-binding transcription factor activity
GGC04_23050	COG1115	amino acid carrier protein
GGC04_23065	COG1741	Belongs to the pirin family
GGC04_23070	COG2259	Doxx family
GGC04_23105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GGC04_23110	COG1960	acyl-CoA dehydrogenase activity
GGC04_23120	COG0183	Belongs to the thiolase family
GGC04_23130	COG1960	acyl-CoA dehydrogenase activity
GGC04_23135	COG1024	Enoyl-CoA hydratase
GGC04_23140	COG1024	Enoyl-CoA hydratase
GGC04_23150	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_23155	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
GGC04_23175	COG3706	GGDEF domain
GGC04_23200	COG2199	diguanylate cyclase activity
GGC04_23200	COG2203	Gaf domain
GGC04_23210	COG2315	Protein conserved in bacteria
GGC04_23250	COG0243	molybdopterin cofactor binding
GGC04_23255	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GGC04_23255	COG1648	precorrin-2 dehydrogenase activity
GGC04_23260	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GGC04_23270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GGC04_23270	COG1116	anion transmembrane transporter activity
GGC04_23275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GGC04_23280	COG1116	anion transmembrane transporter activity
GGC04_23285	COG2146	nitrite reductase [NAD(P)H] activity
GGC04_23285	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GGC04_23290	COG2146	nitrite reductase [NAD(P)H] activity
GGC04_23315	COG3118	belongs to the thioredoxin family
GGC04_23320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GGC04_23330	COG0419	ATPase involved in DNA repair
GGC04_23335	COG2205	protein histidine kinase activity
GGC04_23335	COG0784	Response regulator, receiver
GGC04_23340	COG0156	8-amino-7-oxononanoate synthase activity
GGC04_23350	COG0038	chloride channel
GGC04_23355	COG0523	cobalamin synthesis protein
GGC04_23370	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GGC04_23390	COG2199	diguanylate cyclase activity
GGC04_23405	COG1522	sequence-specific DNA binding
GGC04_23415	COG1473	amidohydrolase
GGC04_23420	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GGC04_23425	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GGC04_23430	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GGC04_23435	COG0006	proline dipeptidase activity
GGC04_23445	COG1522	sequence-specific DNA binding
GGC04_23450	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GGC04_23455	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GGC04_23480	COG2897	thiosulfate sulfurtransferase activity
GGC04_23490	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GGC04_23505	COG0513	Belongs to the DEAD box helicase family
GGC04_23515	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GGC04_23515	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GGC04_23520	COG0814	amino acid
GGC04_23535	COG0513	Belongs to the DEAD box helicase family
GGC04_23565	COG1214	PFAM Peptidase M22, glycoprotease
GGC04_23565	COG0456	acetyltransferase
GGC04_23580	COG0346	lactoylglutathione lyase activity
GGC04_23590	COG3048	D-serine ammonia-lyase activity
GGC04_23595	COG0583	DNA-binding transcription factor activity
GGC04_23605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GGC04_23610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC04_23625	COG0546	phosphoglycolate phosphatase activity
GGC04_23635	COG0800	Aldolase
GGC04_23640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GGC04_23645	COG1263	PTS System
GGC04_23645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GGC04_23655	COG2188	Transcriptional regulator
GGC04_23660	COG1803	Methylglyoxal synthase
GGC04_23665	COG1879	ABC-type sugar transport system periplasmic component
GGC04_23670	COG0784	Response regulator, receiver
GGC04_23670	COG2205	protein histidine kinase activity
GGC04_23670	COG2198	Histidine kinase
GGC04_23685	COG1979	alcohol dehydrogenase
GGC04_23690	COG2207	Transcriptional regulator
GGC04_23695	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GGC04_23700	COG3706	GGDEF domain
GGC04_23705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC04_23705	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GGC04_23705	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GGC04_23710	COG1105	Belongs to the carbohydrate kinase PfkB family
GGC04_23715	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC04_23715	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GGC04_23720	COG1609	Transcriptional regulator
GGC04_23740	COG0725	ABC transporter, periplasmic molybdate-binding protein
GGC04_23745	COG4149	molybdate abc transporter
GGC04_23750	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GGC04_23760	COG5001	Diguanylate cyclase
GGC04_23760	COG4251	negative regulation of phosphorylation
GGC04_23760	COG3706	GGDEF domain
GGC04_23760	COG2203	Gaf domain
GGC04_23765	COG3706	GGDEF domain
GGC04_23780	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GGC04_23785	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GGC04_23795	COG0745	RESPONSE REGULATOR receiver
GGC04_23825	COG0023	Translation Initiation Factor
GGC04_23845	COG1181	Belongs to the D-alanine--D-alanine ligase family
GGC04_23850	COG3266	domain, Protein
GGC04_23855	COG0045	succinate-CoA ligase (ADP-forming) activity
GGC04_23855	COG1042	CoA-binding domain protein
GGC04_23855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GGC04_23860	COG0583	DNA-binding transcription factor activity
GGC04_23865	COG1629	transport
GGC04_23865	COG4771	TonB-dependent receptor
GGC04_23875	COG4533	DNA binding
GGC04_23885	COG2050	protein possibly involved in aromatic compounds catabolism
GGC04_23890	COG4783	chaperone-mediated protein folding
GGC04_23905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GGC04_23910	COG3070	regulator of competence-specific genes
GGC04_23915	COG0840	transmembrane signaling receptor activity
GGC04_23920	COG0784	Response regulator, receiver
GGC04_23920	COG2205	protein histidine kinase activity
GGC04_23925	COG0745	RESPONSE REGULATOR receiver
GGC04_23940	COG1605	Chorismate mutase
GGC04_23975	COG0737	Belongs to the 5'-nucleotidase family
GGC04_23980	COG3593	DNA synthesis involved in DNA repair
GGC04_23990	COG0583	DNA-binding transcription factor activity
GGC04_23995	COG2116	formate transmembrane transporter activity
GGC04_24000	COG2353	YceI-like domain
GGC04_24005	COG3038	cytochrome b561
GGC04_24025	COG3069	C4-dicarboxylate transmembrane transporter activity
GGC04_24030	COG2197	response regulator
GGC04_24035	COG3850	Histidine kinase
GGC04_24040	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GGC04_24050	COG0243	molybdopterin cofactor binding
GGC04_24060	COG3005	denitrification pathway
GGC04_24070	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GGC04_24075	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GGC04_24085	COG1984	allophanate hydrolase subunit 2
GGC04_24090	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GGC04_24095	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GGC04_24100	COG4181	ATPase activity
GGC04_24110	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GGC04_24115	COG5001	Diguanylate cyclase
GGC04_24115	COG3300	MHYT domain
GGC04_24125	COG0484	heat shock protein binding
GGC04_24145	COG0210	DNA helicase
GGC04_24150	COG1289	transmembrane transporter activity
GGC04_24180	COG5002	protein histidine kinase activity
GGC04_24180	COG0784	Response regulator, receiver
GGC04_24195	COG2827	Endonuclease containing a URI domain
GGC04_24220	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GGC04_24225	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GGC04_24230	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GGC04_24235	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
GGC04_24240	COG0247	lactate metabolic process
GGC04_24260	COG0545	Peptidyl-prolyl cis-trans isomerase
GGC04_24270	COG4067	protein conserved in archaea
GGC04_24270	COG0189	ligase activity
GGC04_24280	COG0602	queuosine metabolic process
GGC04_24285	COG1328	CTP reductase activity
GGC04_24330	COG4412	M6 family metalloprotease domain protein
GGC04_24330	COG3291	Pkd domain containing protein
GGC04_24335	COG3240	lipase activity
GGC04_24340	COG2814	Major facilitator Superfamily
GGC04_24345	COG1794	racemase activity, acting on amino acids and derivatives
GGC04_24360	COG0183	Belongs to the thiolase family
GGC04_24375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC04_24380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GGC04_24385	COG1309	transcriptional regulator
GGC04_24390	COG1609	Transcriptional regulator
GGC04_24405	COG2211	Major facilitator Superfamily
GGC04_24410	COG3250	beta-galactosidase activity
GGC04_24450	COG1522	sequence-specific DNA binding
GGC04_24485	COG0515	serine threonine protein kinase
GGC04_24485	COG2815	serine threonine protein kinase
GGC04_24510	COG3501	Rhs element vgr protein
GGC04_24550	COG0739	heme binding
GGC04_24560	COG2203	Gaf domain
GGC04_24560	COG2199	diguanylate cyclase activity
GGC04_24565	COG0840	transmembrane signaling receptor activity
GGC04_24575	COG2271	Major facilitator Superfamily
GGC04_24595	COG4206	TonB-dependent receptor
GGC04_24605	COG0004	ammonium transporteR
GGC04_24620	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GGC04_24625	COG4604	ABC transporter, ATP-binding protein
GGC04_24630	COG4605	iron ion homeostasis
GGC04_24635	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GGC04_24675	COG3706	GGDEF domain
GGC04_24675	COG0745	RESPONSE REGULATOR receiver
GGC04_24685	COG4172	Belongs to the ABC transporter superfamily
GGC04_24690	COG4239	(ABC) transporter, permease
GGC04_24695	COG4174	ABC transporter (Permease)
GGC04_24700	COG4166	transmembrane transport
GGC04_24715	COG0840	transmembrane signaling receptor activity
GGC04_24720	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GGC04_24725	COG1067	ATP-dependent peptidase activity
GGC04_24735	COG4172	Belongs to the ABC transporter superfamily
GGC04_24740	COG0583	DNA-binding transcription factor activity
GGC04_24745	COG1620	l-lactate permease
GGC04_24750	COG1304	FMN binding
GGC04_24770	COG3448	diguanylate cyclase activity
GGC04_24770	COG4175	Glycine betaine
GGC04_24795	COG1309	transcriptional regulator
GGC04_24810	COG1404	Belongs to the peptidase S8 family
GGC04_24815	COG1346	cytolysis
GGC04_24825	COG0516	GMP reductase activity
GGC04_24830	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GGC04_24830	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GGC04_24845	COG3437	response regulator, receiver
GGC04_24850	COG3437	response regulator, receiver
GGC04_24850	COG2205	protein histidine kinase activity
GGC04_24850	COG4999	Histidine kinase
GGC04_24850	COG3850	Histidine kinase
GGC04_24860	COG2172	sigma factor antagonist activity
GGC04_24870	COG1366	Belongs to the anti-sigma-factor antagonist family
GGC04_24875	COG0840	transmembrane signaling receptor activity
GGC04_24890	COG1943	Transposase
GGC04_24960	COG1309	transcriptional regulator
GGC04_24975	COG1360	Flagellar Motor Protein
GGC04_25000	COG0702	epimerase
GGC04_25025	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
GGC04_25030	COG0840	transmembrane signaling receptor activity
GGC04_25035	COG1879	ABC-type sugar transport system periplasmic component
GGC04_25050	COG5001	Diguanylate cyclase
GGC04_25050	COG3706	GGDEF domain
GGC04_25050	COG4251	negative regulation of phosphorylation
GGC04_25050	COG2203	Gaf domain
GGC04_25065	COG0431	NADPH-dependent FMN reductase
GGC04_25070	COG0583	DNA-binding transcription factor activity
GGC04_25075	COG0583	DNA-binding transcription factor activity
GGC04_25095	COG0840	transmembrane signaling receptor activity
GGC04_25110	COG5001	Diguanylate cyclase
GGC04_25110	COG3706	GGDEF domain
GGC04_25110	COG4251	negative regulation of phosphorylation
GGC04_25110	COG2203	Gaf domain
GGC04_25120	COG0745	RESPONSE REGULATOR receiver
GGC04_25130	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_25135	COG0583	DNA-binding transcription factor activity
GGC04_25145	COG3527	Alpha-acetolactate decarboxylase
GGC04_25155	COG0745	RESPONSE REGULATOR receiver
GGC04_25160	COG2205	protein histidine kinase activity
GGC04_25265	COG0671	phosphoesterase, PA-phosphatase related
GGC04_25280	COG0113	porphobilinogen synthase activity
GGC04_25285	COG0183	Belongs to the thiolase family
GGC04_25295	COG3246	L-lysine catabolic process to acetate
GGC04_25310	COG0604	alcohol dehydrogenase
GGC04_25320	COG0702	epimerase
GGC04_25340	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
GGC04_25355	COG0583	DNA-binding transcription factor activity
GGC04_25360	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_25460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GGC04_25480	COG2084	Dehydrogenase
GGC04_25540	COG4774	siderophore transport
GGC04_25565	COG0494	nUDIX hydrolase
GGC04_25600	COG1742	UPF0060 membrane protein
GGC04_25605	COG0251	oxidation-reduction process
GGC04_25615	COG0583	DNA-binding transcription factor activity
GGC04_25645	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GGC04_25650	COG1051	belongs to the nudix hydrolase family
GGC04_25685	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GGC04_25685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GGC04_25705	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_25715	COG2274	protein secretion by the type I secretion system
GGC04_25725	COG2274	protein secretion by the type I secretion system
GGC04_25735	COG0583	DNA-binding transcription factor activity
GGC04_25765	COG1280	lysine exporter protein (LysE YggA)
GGC04_25770	COG1917	Cupin 2, conserved barrel domain protein
GGC04_25770	COG2207	Transcriptional regulator
GGC04_25785	COG0625	glutathione transferase activity
GGC04_25790	COG0583	DNA-binding transcription factor activity
GGC04_25815	COG1917	Cupin 2, conserved barrel domain protein
GGC04_25815	COG2207	Transcriptional regulator
GGC04_25825	COG4608	Belongs to the ABC transporter superfamily
GGC04_25830	COG0444	Belongs to the ABC transporter superfamily
GGC04_25835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GGC04_25855	COG1609	Transcriptional regulator
GGC04_25865	COG4580	involved in the transport of maltose and maltodextrins
GGC04_25895	COG0071	Belongs to the small heat shock protein (HSP20) family
GGC04_25900	COG0459	protein refolding
GGC04_25945	COG2169	Transcriptional regulator
GGC04_25945	COG1917	Cupin 2, conserved barrel domain protein
GGC04_26005	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GGC04_26015	COG1335	isochorismatase
GGC04_26020	COG2169	Transcriptional regulator
GGC04_26050	COG2267	carboxylic ester hydrolase activity
GGC04_26085	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GGC04_26095	COG3706	GGDEF domain
GGC04_26095	COG5001	Diguanylate cyclase
GGC04_26095	COG2203	Gaf domain
GGC04_26095	COG4251	negative regulation of phosphorylation
GGC04_26100	COG0745	RESPONSE REGULATOR receiver
GGC04_26100	COG3706	GGDEF domain
GGC04_26135	COG2003	Belongs to the UPF0758 family
GGC04_26240	COG0305	Participates in initiation and elongation during chromosome replication
GGC04_26245	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GGC04_26395	COG4771	TonB-dependent receptor
GGC04_26405	COG4974	Belongs to the 'phage' integrase family
GGC04_26415	COG1028	Short-chain dehydrogenase reductase Sdr
GGC04_26420	COG0583	DNA-binding transcription factor activity
GGC04_26460	COG2026	Addiction module toxin, RelE StbE family
GGC04_26515	COG1609	Transcriptional regulator
GGC04_26525	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GGC04_26535	COG1280	lysine exporter protein (LysE YggA)
GGC04_26545	COG0735	belongs to the Fur family
GGC04_26650	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GGC04_26650	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GGC04_26660	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GGC04_26680	COG1181	Belongs to the D-alanine--D-alanine ligase family
GGC04_26685	COG4191	Histidine kinase
GGC04_26755	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GGC04_26770	COG1192	Involved in chromosome partitioning
GGC04_26780	COG2814	Major facilitator Superfamily
GGC04_26795	COG3033	Beta-eliminating lyase
GGC04_26825	COG0745	RESPONSE REGULATOR receiver
GGC04_26835	COG4191	Histidine kinase
GGC04_26840	COG3300	MHYT domain
GGC04_26840	COG5001	Diguanylate cyclase
GGC04_26855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GGC04_26855	COG4191	Histidine kinase
GGC04_26915	COG0860	N-Acetylmuramoyl-L-alanine amidase
GGC04_26915	COG2247	cell wall binding repeat
GGC04_26955	COG3093	addiction module antidote protein HigA
GGC04_26960	COG3549	Plasmid maintenance system killer
GGC04_26995	COG5301	cellulose 1,4-beta-cellobiosidase activity
GGC04_27190	COG0629	single-stranded DNA binding
GGC04_27340	COG1959	2 iron, 2 sulfur cluster binding