locus-tag	class	description
FIU99_00010	COG0592	DNA-directed DNA polymerase activity
FIU99_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FIU99_00020	COG0187	DNA topoisomerase II activity
FIU99_00025	COG0071	Belongs to the small heat shock protein (HSP20) family
FIU99_00030	COG3977	Valine--pyruvate aminotransferase
FIU99_00035	COG0751	glycine-tRNA ligase activity
FIU99_00045	COG2119	membrane
FIU99_00055	COG0425	Belongs to the sulfur carrier protein TusA family
FIU99_00070	COG0604	alcohol dehydrogenase
FIU99_00080	COG0129	dihydroxy-acid dehydratase activity
FIU99_00085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FIU99_00090	COG3978	acetolactate synthase activity
FIU99_00100	COG0606	chelatase, subunit chli
FIU99_00190	COG0606	chelatase, subunit chli
FIU99_00200	COG0204	Acyl-transferase
FIU99_00205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIU99_00210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FIU99_00220	COG3084	Protein conserved in bacteria
FIU99_00225	COG4326	sporulation control protein
FIU99_00230	COG1272	protein, Hemolysin III
FIU99_00240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIU99_00245	COG0569	domain protein
FIU99_00250	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FIU99_00250	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FIU99_00260	COG0242	peptide deformylase activity
FIU99_00265	COG0758	DNA mediated transformation
FIU99_00270	COG2922	Belongs to the Smg family
FIU99_00275	COG0551	DNA topoisomerase type I activity
FIU99_00280	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FIU99_00285	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FIU99_00295	COG0408	coproporphyrinogen oxidase activity
FIU99_00310	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FIU99_00350	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FIU99_00360	COG2204	response regulator
FIU99_00365	COG3852	Histidine kinase
FIU99_00370	COG0174	glutamine synthetase
FIU99_00390	COG1490	D-aminoacyl-tRNA deacylase activity
FIU99_00395	COG0456	acetyltransferase
FIU99_00405	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FIU99_00415	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FIU99_00420	COG3031	protein transport across the cell outer membrane
FIU99_00430	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FIU99_00435	COG1459	type II secretion system
FIU99_00440	COG2165	general secretion pathway protein
FIU99_00445	COG2165	general secretion pathway protein
FIU99_00450	COG2165	general secretion pathway protein
FIU99_00455	COG4795	General secretion pathway protein
FIU99_00460	COG3156	type II secretion system protein K
FIU99_00465	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FIU99_00470	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FIU99_00485	COG0745	RESPONSE REGULATOR receiver
FIU99_00490	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FIU99_00500	COG2183	response to ionizing radiation
FIU99_00510	COG0596	Alpha beta hydrolase
FIU99_00520	COG0316	Belongs to the HesB IscA family
FIU99_00520	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FIU99_00525	COG0494	nUDIX hydrolase
FIU99_00530	COG1218	3'(2'),5'-bisphosphate nucleotidase
FIU99_00535	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FIU99_00540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIU99_00545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FIU99_00560	COG1595	DNA-templated transcription, initiation
FIU99_00590	COG0848	biopolymer transport protein
FIU99_00600	COG2252	PERMEase
FIU99_00605	COG2831	hemolysin activation secretion protein
FIU99_00610	COG3210	domain, Protein
FIU99_00620	COG1561	YicC-like family, N-terminal region
FIU99_00630	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FIU99_00635	COG1560	Kdo2-lipid A biosynthetic process
FIU99_00640	COG1560	Kdo2-lipid A biosynthetic process
FIU99_00645	COG1309	transcriptional regulator
FIU99_00650	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FIU99_00655	COG2003	Belongs to the UPF0758 family
FIU99_00685	COG0859	PFAM glycosyl transferase family 9
FIU99_00690	COG0463	Glycosyl transferase, family 2
FIU99_00695	COG0859	PFAM glycosyl transferase family 9
FIU99_00700	COG3642	lipopolysaccharide core region biosynthetic process
FIU99_00715	COG1519	Transferase
FIU99_00730	COG0859	PFAM glycosyl transferase family 9
FIU99_00760	COG1086	Polysaccharide biosynthesis protein
FIU99_00765	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FIU99_00775	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
FIU99_00780	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FIU99_00790	COG2089	acid synthase
FIU99_00800	COG0318	PFAM AMP-dependent synthetase and ligase
FIU99_00810	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FIU99_00825	COG4310	Domain of unknown function (DUF2172)
FIU99_00835	COG2226	methyltransferase
FIU99_00870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FIU99_00875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FIU99_00880	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FIU99_00880	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FIU99_00885	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FIU99_00915	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FIU99_00925	COG1494	fructose-1,6-bisphosphatase
FIU99_00935	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FIU99_00940	COG0460	homoserine dehydrogenase
FIU99_00940	COG0527	aspartate kinase activity
FIU99_00945	COG0626	cystathionine gamma-synthase activity
FIU99_00955	COG0281	malic enzyme
FIU99_00965	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FIU99_00970	COG1609	Transcriptional regulator
FIU99_00975	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FIU99_01005	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FIU99_01010	COG1053	succinate dehydrogenase
FIU99_01015	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FIU99_01020	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU99_01055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIU99_01070	COG1045	serine acetyltransferase
FIU99_01075	COG1695	Transcriptional regulator
FIU99_01080	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FIU99_01085	COG1573	uracil-dna glycosylase
FIU99_01090	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIU99_01095	COG3068	Protein conserved in bacteria
FIU99_01100	COG1253	flavin adenine dinucleotide binding
FIU99_01115	COG0151	Belongs to the GarS family
FIU99_01125	COG0789	Transcriptional regulator
FIU99_01130	COG3706	GGDEF domain
FIU99_01135	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FIU99_01140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FIU99_01145	COG2264	protein methyltransferase activity
FIU99_01150	COG0439	Biotin carboxylase
FIU99_01155	COG0511	ligase activity, forming carbon-carbon bonds
FIU99_01160	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FIU99_01165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIU99_01180	COG2814	Major facilitator Superfamily
FIU99_01185	COG0784	Response regulator, receiver
FIU99_01185	COG2205	protein histidine kinase activity
FIU99_01195	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIU99_01205	COG2095	MarC family integral membrane protein
FIU99_01215	COG4232	protein-disulfide reductase activity
FIU99_01220	COG1438	arginine binding
FIU99_01225	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FIU99_01230	COG0540	Belongs to the ATCase OTCase family
FIU99_01240	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FIU99_01255	COG1288	antiporter activity
FIU99_01260	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FIU99_01265	COG1027	Aspartate ammonia-lyase
FIU99_01350	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FIU99_01370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIU99_01375	COG3954	Phosphoribulokinase
FIU99_01385	COG0429	hydrolase of the alpha beta-hydrolase fold
FIU99_01395	COG0488	(ABC) transporter
FIU99_01415	COG1047	Peptidyl-prolyl cis-trans
FIU99_01425	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FIU99_01430	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FIU99_01435	COG0402	S-adenosylhomocysteine deaminase activity
FIU99_01440	COG0557	exoribonuclease II activity
FIU99_01445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIU99_01450	COG0051	transcription antitermination factor activity, RNA binding
FIU99_01460	COG0088	Forms part of the polypeptide exit tunnel
FIU99_01480	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FIU99_01485	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FIU99_01515	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FIU99_01530	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FIU99_01545	COG1841	ribosomal large subunit assembly
FIU99_01555	COG0201	protein transport
FIU99_01565	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FIU99_01570	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FIU99_01585	COG0203	ribosomal protein L17
FIU99_01595	COG0545	Peptidyl-prolyl cis-trans isomerase
FIU99_01610	COG2153	protein acetylation
FIU99_01620	COG0737	Belongs to the 5'-nucleotidase family
FIU99_01625	COG1648	precorrin-2 dehydrogenase activity
FIU99_01625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FIU99_01640	COG0471	metal ion transport
FIU99_01640	COG3273	potassium ion transport
FIU99_01645	COG0529	Catalyzes the synthesis of activated sulfate
FIU99_01655	COG0735	belongs to the Fur family
FIU99_01665	COG3437	response regulator, receiver
FIU99_01695	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FIU99_01700	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIU99_01760	COG1410	methionine synthase
FIU99_01760	COG0646	methionine synthase
FIU99_01765	COG2239	Acts as a magnesium transporter
FIU99_01770	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU99_01780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU99_01785	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FIU99_01795	COG1137	ATPase activity
FIU99_01800	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FIU99_01810	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FIU99_01815	COG0517	IMP dehydrogenase activity
FIU99_01815	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FIU99_01825	COG1127	ABC transporter
FIU99_01830	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FIU99_01835	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FIU99_01840	COG2854	intermembrane phospholipid transfer
FIU99_01850	COG5007	Belongs to the BolA IbaG family
FIU99_01860	COG0204	Acyl-transferase
FIU99_01865	COG2235	arginine
FIU99_01885	COG0589	response to stress
FIU99_01910	COG0039	L-malate dehydrogenase activity
FIU99_01920	COG0251	oxidation-reduction process
FIU99_01925	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FIU99_01940	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FIU99_01945	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FIU99_01955	COG0564	pseudouridine synthase activity
FIU99_01960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FIU99_01970	COG4269	membrane
FIU99_01980	COG0525	valine-tRNA ligase activity
FIU99_01985	COG2927	DNA polymerase III (CHI subunit)
FIU99_01995	COG0795	lipopolysaccharide-transporting ATPase activity
FIU99_02000	COG0795	lipopolysaccharide-transporting ATPase activity
FIU99_02005	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FIU99_02010	COG1546	Belongs to the CinA family
FIU99_02015	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FIU99_02020	COG2137	regulation of response to DNA damage stimulus
FIU99_02030	COG0527	aspartate kinase activity
FIU99_02080	COG3630	sodium ion export across plasma membrane
FIU99_02085	COG5016	pyruvate
FIU99_02085	COG0511	ligase activity, forming carbon-carbon bonds
FIU99_02090	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FIU99_02095	COG2130	NADP-dependent
FIU99_02100	COG1238	metal cluster binding
FIU99_02105	COG0612	Peptidase, M16
FIU99_02110	COG2918	glutathione biosynthetic process
FIU99_02120	COG1854	S-ribosylhomocysteine lyase activity
FIU99_02135	COG0582	viral genome integration into host DNA
FIU99_02165	COG0328	RNA-DNA hybrid ribonuclease activity
FIU99_02180	COG3547	Transposase (IS116 IS110 IS902 family)
FIU99_02200	COG2203	Gaf domain
FIU99_02200	COG3706	GGDEF domain
FIU99_02200	COG4251	negative regulation of phosphorylation
FIU99_02200	COG5001	Diguanylate cyclase
FIU99_02210	COG1879	ABC-type sugar transport system periplasmic component
FIU99_02215	COG0840	transmembrane signaling receptor activity
FIU99_02235	COG0840	transmembrane signaling receptor activity
FIU99_02240	COG3706	GGDEF domain
FIU99_02240	COG2203	Gaf domain
FIU99_02240	COG4251	negative regulation of phosphorylation
FIU99_02240	COG5001	Diguanylate cyclase
FIU99_02270	COG0640	Transcriptional regulator
FIU99_02310	COG2003	Belongs to the UPF0758 family
FIU99_02320	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FIU99_02350	COG3437	response regulator, receiver
FIU99_02410	COG0473	3-isopropylmalate dehydrogenase activity
FIU99_02415	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FIU99_02435	COG0583	DNA-binding transcription factor activity
FIU99_02440	COG1022	Amp-dependent synthetase and ligase
FIU99_02445	COG0028	Belongs to the TPP enzyme family
FIU99_02450	COG0440	acetolactate synthase activity
FIU99_02455	COG0584	glycerophosphoryl diester phosphodiesterase
FIU99_02460	COG2271	Major facilitator Superfamily
FIU99_02465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIU99_02475	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FIU99_02485	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FIU99_02495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU99_02500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU99_02525	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FIU99_02530	COG1595	DNA-templated transcription, initiation
FIU99_02545	COG3086	response to oxidative stress
FIU99_02550	COG0481	GTPase activity
FIU99_02555	COG0681	Belongs to the peptidase S26 family
FIU99_02565	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FIU99_02570	COG1381	Involved in DNA repair and RecF pathway recombination
FIU99_02580	COG0736	holo-[acyl-carrier-protein] synthase activity
FIU99_02585	COG4999	Histidine kinase
FIU99_02585	COG3850	Histidine kinase
FIU99_02585	COG3437	response regulator, receiver
FIU99_02585	COG2205	protein histidine kinase activity
FIU99_02590	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FIU99_02595	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FIU99_02600	COG3956	TIGRFAM MazG family protein
FIU99_02610	COG0148	phosphopyruvate hydratase activity
FIU99_02615	COG0617	tRNA 3'-terminal CCA addition
FIU99_02620	COG3409	Peptidoglycan-binding domain 1 protein
FIU99_02620	COG3267	Type II secretory pathway component ExeA
FIU99_02630	COG4991	sh3 domain protein
FIU99_02635	COG0306	phosphate transporter
FIU99_02640	COG1392	Phosphate transport regulator
FIU99_02645	COG3025	triphosphatase activity
FIU99_02650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIU99_02660	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FIU99_02675	COG0745	RESPONSE REGULATOR receiver
FIU99_02705	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FIU99_02710	COG2860	membrane
FIU99_02715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FIU99_02720	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FIU99_02745	COG1846	Transcriptional regulator
FIU99_02750	COG0534	Mate efflux family protein
FIU99_02755	COG2204	response regulator
FIU99_02770	COG0667	Aldo Keto reductase
FIU99_02780	COG3066	DNA modification
FIU99_02795	COG0730	response to heat
FIU99_02805	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FIU99_02810	COG1283	sodium-dependent phosphate transmembrane transporter activity
FIU99_02815	COG0583	DNA-binding transcription factor activity
FIU99_02820	COG0640	Transcriptional regulator
FIU99_02825	COG0268	Binds directly to 16S ribosomal RNA
FIU99_02830	COG0728	peptidoglycan biosynthetic process
FIU99_02835	COG0196	riboflavin kinase activity
FIU99_02850	COG1047	Peptidyl-prolyl cis-trans
FIU99_02855	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FIU99_02860	COG1966	Carbon starvation protein
FIU99_02870	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FIU99_02875	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FIU99_02880	COG2971	BadF BadG BcrA BcrD
FIU99_02890	COG1737	Transcriptional regulator
FIU99_02895	COG1472	Belongs to the glycosyl hydrolase 3 family
FIU99_02900	COG3279	Response regulator of the LytR AlgR family
FIU99_02905	COG3275	phosphorelay sensor kinase activity
FIU99_02910	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FIU99_02915	COG1605	Chorismate mutase
FIU99_02915	COG0287	Prephenate dehydrogenase
FIU99_02920	COG0739	heme binding
FIU99_02930	COG0488	(ABC) transporter
FIU99_02935	COG0741	lytic transglycosylase activity
FIU99_02940	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FIU99_02945	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FIU99_02950	COG5001	Diguanylate cyclase
FIU99_02955	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FIU99_02960	COG1605	Chorismate mutase
FIU99_02960	COG0077	Prephenate dehydratase
FIU99_02965	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FIU99_02970	COG0741	lytic transglycosylase activity
FIU99_02975	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU99_02980	COG0564	pseudouridine synthase activity
FIU99_02990	COG0542	response to heat
FIU99_03030	COG0483	inositol monophosphate 1-phosphatase activity
FIU99_03040	COG1959	2 iron, 2 sulfur cluster binding
FIU99_03050	COG0822	iron-sulfur transferase activity
FIU99_03070	COG0633	Ferredoxin
FIU99_03075	COG2975	iron-sulfur cluster assembly
FIU99_03080	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FIU99_03090	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FIU99_03095	COG0583	DNA-binding transcription factor activity
FIU99_03105	COG0583	DNA-binding transcription factor activity
FIU99_03110	COG1022	Amp-dependent synthetase and ligase
FIU99_03115	COG2169	Transcriptional regulator
FIU99_03145	COG4964	Belongs to the GSP D family
FIU99_03195	COG2169	Transcriptional regulator
FIU99_03200	COG1486	melibiose metabolic process
FIU99_03205	COG2211	Major facilitator Superfamily
FIU99_03215	COG3408	Glycogen debranching enzyme
FIU99_03215	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FIU99_03230	COG1309	transcriptional regulator
FIU99_03235	COG0531	amino acid
FIU99_03240	COG2731	YhcH YjgK YiaL family protein
FIU99_03245	COG3250	beta-galactosidase activity
FIU99_03250	COG1609	Transcriptional regulator
FIU99_03255	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FIU99_03260	COG1085	galactose-1-phosphate uridylyltransferase
FIU99_03270	COG2017	converts alpha-aldose to the beta-anomer
FIU99_03280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIU99_03290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU99_03290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU99_03290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU99_03295	COG2207	Transcriptional regulator
FIU99_03305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU99_03315	COG2171	N-acyltransferase activity
FIU99_03320	COG0450	alkyl hydroperoxide reductase
FIU99_03325	COG0583	DNA-binding transcription factor activity
FIU99_03330	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FIU99_03355	COG0517	IMP dehydrogenase activity
FIU99_03360	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FIU99_03370	COG1862	Preprotein translocase
FIU99_03375	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIU99_03380	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIU99_03395	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FIU99_03400	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FIU99_03415	COG0745	RESPONSE REGULATOR receiver
FIU99_03420	COG5002	protein histidine kinase activity
FIU99_03430	COG0248	Ppx GppA phosphatase
FIU99_03435	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FIU99_03440	COG0573	inorganic phosphate transmembrane transporter activity
FIU99_03445	COG0581	inorganic phosphate transmembrane transporter activity
FIU99_03450	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIU99_03455	COG0704	Plays a role in the regulation of phosphate uptake
FIU99_03470	COG3141	response to X-ray
FIU99_03475	COG1309	transcriptional regulator
FIU99_03480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU99_03500	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FIU99_03505	COG1074	ATP-dependent DNA helicase activity
FIU99_03510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FIU99_03530	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FIU99_03535	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FIU99_03540	COG2166	iron-sulfur cluster assembly
FIU99_03550	COG1426	Protein conserved in bacteria
FIU99_03560	COG0124	histidyl-tRNA synthetase
FIU99_03565	COG2976	Protein conserved in bacteria
FIU99_03570	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU99_03575	COG1160	GTP binding
FIU99_03585	COG2199	diguanylate cyclase activity
FIU99_03585	COG2203	Gaf domain
FIU99_03600	COG0517	IMP dehydrogenase activity
FIU99_03600	COG0516	GMP reductase activity
FIU99_03615	COG1584	GPR1 FUN34 yaaH family protein
FIU99_03620	COG1115	amino acid carrier protein
FIU99_03630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU99_03650	COG2873	o-acetylhomoserine
FIU99_03655	COG0784	Response regulator, receiver
FIU99_03655	COG0835	chemotaxis
FIU99_03660	COG0204	Acyl-transferase
FIU99_03680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU99_03685	COG0668	transmembrane transport
FIU99_03705	COG2867	negative regulation of translational initiation
FIU99_03715	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU99_03720	COG0497	DNA recombination
FIU99_03730	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FIU99_03735	COG1301	dicarboxylic acid transport
FIU99_03740	COG0443	Heat shock 70 kDa protein
FIU99_03755	COG4970	Tfp pilus assembly protein FimT
FIU99_03775	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FIU99_03780	COG0590	tRNA wobble adenosine to inosine editing
FIU99_03790	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FIU99_03795	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FIU99_03795	COG0047	phosphoribosylformylglycinamidine synthase activity
FIU99_03820	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FIU99_03825	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FIU99_03830	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FIU99_03835	COG1187	pseudouridine synthase activity
FIU99_03840	COG2840	Smr protein MutS2
FIU99_03865	COG3104	oligopeptide transport
FIU99_03870	COG0367	asparagine synthase
FIU99_03875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FIU99_03875	COG4651	solute:proton antiporter activity
FIU99_03880	COG1846	Transcriptional regulator
FIU99_03880	COG1940	carbohydrate kinase activity
FIU99_03885	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FIU99_03890	COG2190	(PTS) system
FIU99_03890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU99_03890	COG1263	PTS System
FIU99_03910	COG0716	FMN binding
FIU99_03920	COG0596	Alpha beta hydrolase
FIU99_03925	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FIU99_03930	COG0033	Phosphoglucomutase
FIU99_03940	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FIU99_03955	COG2009	succinate dehydrogenase
FIU99_03960	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FIU99_03965	COG1053	succinate dehydrogenase
FIU99_03970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FIU99_03975	COG0567	Dehydrogenase, E1 component
FIU99_03980	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIU99_03995	COG1943	Transposase
FIU99_04025	COG3098	single-species biofilm formation
FIU99_04030	COG0564	pseudouridine synthase activity
FIU99_04040	COG0142	geranyltranstransferase activity
FIU99_04050	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FIU99_04060	COG0301	tRNA thio-modification
FIU99_04060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIU99_04070	COG0583	DNA-binding transcription factor activity
FIU99_04095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIU99_04100	COG1611	Belongs to the LOG family
FIU99_04105	COG0745	RESPONSE REGULATOR receiver
FIU99_04105	COG3706	GGDEF domain
FIU99_04125	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FIU99_04140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIU99_04145	COG1393	Belongs to the ArsC family
FIU99_04175	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FIU99_04180	COG0437	4 iron, 4 sulfur cluster binding
FIU99_04185	COG3301	Polysulphide reductase, NrfD
FIU99_04190	COG1138	Cytochrome C-type biogenesis protein
FIU99_04195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU99_04200	COG3088	subunit of a heme lyase
FIU99_04200	COG4235	cytochrome complex assembly
FIU99_04210	COG2837	iron assimilation
FIU99_04225	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FIU99_04235	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FIU99_04245	COG1516	flagellar protein fliS
FIU99_04255	COG2204	response regulator
FIU99_04260	COG4191	Histidine kinase
FIU99_04265	COG2204	response regulator
FIU99_04270	COG1677	Flagellar hook-basal body complex protein FliE
FIU99_04280	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FIU99_04330	COG1987	bacterial-type flagellum assembly
FIU99_04335	COG1684	flagellar biosynthetic protein fliR
FIU99_04350	COG2890	protein-(glutamine-N5) methyltransferase activity
FIU99_04355	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FIU99_04365	COG2860	membrane
FIU99_04370	COG3101	peptidyl-lysine hydroxylation
FIU99_04400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FIU99_04405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIU99_04410	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FIU99_04420	COG0101	tRNA pseudouridine synthase activity
FIU99_04430	COG0285	dihydrofolate synthase activity
FIU99_04435	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FIU99_04440	COG1286	toxin biosynthetic process
FIU99_04445	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FIU99_04450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIU99_04455	COG1121	(ABC) transporter
FIU99_04460	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FIU99_04465	COG4977	sequence-specific DNA binding
FIU99_04470	COG1918	ferrous iron import across plasma membrane
FIU99_04475	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FIU99_04490	COG0018	arginyl-trna synthetase
FIU99_04495	COG3102	Protein conserved in bacteria
FIU99_04500	COG1025	Belongs to the peptidase M16 family
FIU99_04505	COG2062	phosphohistidine phosphatase, SixA
FIU99_04520	COG0455	bacterial-type flagellum organization
FIU99_04535	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FIU99_04540	COG2198	Histidine kinase
FIU99_04540	COG0643	Histidine kinase
FIU99_04545	COG2201	protein-glutamate methylesterase activity
FIU99_04550	COG1192	Involved in chromosome partitioning
FIU99_04560	COG0835	chemotaxis
FIU99_04570	COG4133	protoheme IX ABC transporter activity
FIU99_04575	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIU99_04580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIU99_04585	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIU99_04595	COG1138	Cytochrome C-type biogenesis protein
FIU99_04600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU99_04605	COG3088	subunit of a heme lyase
FIU99_04605	COG4235	cytochrome complex assembly
FIU99_04615	COG2853	Lipoprotein
FIU99_04620	COG2067	long-chain fatty acid transport protein
FIU99_04625	COG2067	long-chain fatty acid transport protein
FIU99_04640	COG0183	Belongs to the thiolase family
FIU99_04650	COG0778	Nitroreductase
FIU99_04655	COG0583	DNA-binding transcription factor activity
FIU99_04660	COG0745	RESPONSE REGULATOR receiver
FIU99_04675	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FIU99_04685	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FIU99_04725	COG0745	RESPONSE REGULATOR receiver
FIU99_04730	COG2205	protein histidine kinase activity
FIU99_04735	COG1653	transport
FIU99_04750	COG3842	ATPase activity
FIU99_04755	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU99_04760	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIU99_04765	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU99_04775	COG2204	response regulator
FIU99_04800	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FIU99_04805	COG0776	regulation of translation
FIU99_04810	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIU99_04815	COG1555	photosystem II stabilization
FIU99_04825	COG0539	negative regulation of cytoplasmic translation
FIU99_04835	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FIU99_04840	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FIU99_04845	COG0284	orotidine-5'-phosphate decarboxylase activity
FIU99_04880	COG4120	Belongs to the binding-protein-dependent transport system permease family
FIU99_04890	COG3706	GGDEF domain
FIU99_04895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FIU99_04915	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FIU99_04920	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FIU99_04930	COG0252	asparaginase activity
FIU99_04935	COG0616	signal peptide processing
FIU99_04940	COG1902	pentaerythritol trinitrate reductase activity
FIU99_04940	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU99_04945	COG0788	formyltetrahydrofolate deformylase activity
FIU99_04955	COG1199	ATP-dependent helicase activity
FIU99_04960	COG1214	PFAM Peptidase M22, glycoprotease
FIU99_04975	COG2267	carboxylic ester hydrolase activity
FIU99_04980	COG0318	PFAM AMP-dependent synthetase and ligase
FIU99_04985	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FIU99_04990	COG0659	secondary active sulfate transmembrane transporter activity
FIU99_04995	COG1530	ribonuclease E activity
FIU99_05000	COG0564	pseudouridine synthase activity
FIU99_05005	COG0424	maF-like protein
FIU99_05010	COG1399	metal-binding, possibly nucleic acid-binding protein
FIU99_05025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FIU99_05050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FIU99_05055	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FIU99_05060	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FIU99_05065	COG0470	DNA polymerase III
FIU99_05070	COG0084	hydrolase, TatD family'
FIU99_05075	COG1263	PTS System
FIU99_05075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU99_05085	COG1943	Transposase
FIU99_05095	COG0733	neurotransmitter:sodium symporter activity
FIU99_05110	COG4667	esterase of the alpha-beta hydrolase superfamily
FIU99_05115	COG0469	pyruvate kinase activity
FIU99_05120	COG1940	carbohydrate kinase activity
FIU99_05125	COG0835	chemotaxis
FIU99_05125	COG0784	Response regulator, receiver
FIU99_05145	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_05150	COG0616	signal peptide processing
FIU99_05155	COG0513	Belongs to the DEAD box helicase family
FIU99_05170	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FIU99_05175	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FIU99_05185	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FIU99_05190	COG0436	Aminotransferase
FIU99_05195	COG1169	isochorismate synthase
FIU99_05200	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FIU99_05205	COG0596	Alpha beta hydrolase
FIU99_05215	COG1441	menaquinone biosynthetic process
FIU99_05230	COG2855	membrane
FIU99_05235	COG0477	Major facilitator Superfamily
FIU99_05260	COG1522	sequence-specific DNA binding
FIU99_05275	COG1946	Acyl-CoA thioesterase
FIU99_05280	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FIU99_05295	COG3706	GGDEF domain
FIU99_05345	COG1414	Transcriptional regulator
FIU99_05350	COG0280	phosphate acetyltransferase
FIU99_05355	COG0730	response to heat
FIU99_05375	COG2855	membrane
FIU99_05390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU99_05395	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU99_05400	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIU99_05420	COG1472	Belongs to the glycosyl hydrolase 3 family
FIU99_05425	COG3876	Protein conserved in bacteria
FIU99_05435	COG1215	transferase activity, transferring glycosyl groups
FIU99_05450	COG3397	chitin binding
FIU99_05455	COG1770	oligopeptidase
FIU99_05465	COG3227	Zinc metalloprotease (Elastase)
FIU99_05475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU99_05485	COG0577	efflux transmembrane transporter activity
FIU99_05495	COG0577	efflux transmembrane transporter activity
FIU99_05495	COG1136	(ABC) transporter
FIU99_05515	COG0330	HflC and HflK could
FIU99_05525	COG0840	transmembrane signaling receptor activity
FIU99_05530	COG1404	Belongs to the peptidase S8 family
FIU99_05555	COG3706	GGDEF domain
FIU99_05560	COG2067	long-chain fatty acid transport protein
FIU99_05575	COG0601	transmembrane transport
FIU99_05580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU99_05585	COG0444	Belongs to the ABC transporter superfamily
FIU99_05595	COG0435	Glutathione S-transferase
FIU99_05600	COG3706	GGDEF domain
FIU99_05605	COG0857	belongs to the CobB CobQ family
FIU99_05605	COG0280	phosphate acetyltransferase
FIU99_05615	COG3092	negative regulation of chromosome organization
FIU99_05620	COG0686	Belongs to the AlaDH PNT family
FIU99_05630	COG1674	ftsk spoiiie
FIU99_05645	COG2186	Transcriptional regulator
FIU99_05660	COG0537	adenosine 5'-monophosphoramidase activity
FIU99_05690	COG1252	NADH dehydrogenase
FIU99_05695	COG1943	Transposase
FIU99_05715	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FIU99_05725	COG4591	ABC-type transport system involved in lipoprotein release permease component
FIU99_05730	COG1136	(ABC) transporter
FIU99_05735	COG4591	ABC-type transport system involved in lipoprotein release permease component
FIU99_05745	COG0658	competence protein
FIU99_05745	COG2333	competence protein COMEC
FIU99_05750	COG1132	(ABC) transporter
FIU99_05765	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FIU99_05770	COG2719	SpoVR family
FIU99_05775	COG2718	Belongs to the UPF0229 family
FIU99_05780	COG2766	serine protein kinase
FIU99_05785	COG3713	MltA-interacting MipA family protein
FIU99_05800	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FIU99_05815	COG1882	Formate acetyltransferase
FIU99_05835	COG4215	(ABC) transporter
FIU99_05850	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FIU99_05990	COG3772	lysozyme
FIU99_06005	COG4695	Portal protein
FIU99_06045	COG4386	tail sheath protein
FIU99_06080	COG3646	Phage regulatory protein
FIU99_06110	COG1454	alcohol dehydrogenase
FIU99_06110	COG1012	belongs to the aldehyde dehydrogenase family
FIU99_06115	COG1737	Transcriptional regulator
FIU99_06120	COG0076	glutamate decarboxylase activity
FIU99_06130	COG2431	L-lysine efflux transmembrane transporter activity
FIU99_06140	COG3070	regulator of competence-specific genes
FIU99_06155	COG4191	Histidine kinase
FIU99_06155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU99_06165	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FIU99_06175	COG1032	radical SAM domain protein
FIU99_06195	COG0583	DNA-binding transcription factor activity
FIU99_06200	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FIU99_06205	COG1764	response to oxidative stress
FIU99_06210	COG1846	Transcriptional regulator
FIU99_06220	COG0583	DNA-binding transcription factor activity
FIU99_06230	COG0673	inositol 2-dehydrogenase activity
FIU99_06235	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIU99_06255	COG0840	transmembrane signaling receptor activity
FIU99_06260	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FIU99_06275	COG3152	Membrane
FIU99_06320	COG1858	cytochrome C peroxidase
FIU99_06335	COG0443	Heat shock 70 kDa protein
FIU99_06385	COG1643	Atp-dependent helicase
FIU99_06395	COG1301	dicarboxylic acid transport
FIU99_06400	COG0159	tryptophan synthase activity
FIU99_06405	COG0133	tryptophan synthase activity
FIU99_06410	COG0135	phosphoribosylanthranilate isomerase activity
FIU99_06410	COG0134	indole-3-glycerol-phosphate synthase activity
FIU99_06415	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FIU99_06420	COG0512	Glutamine amidotransferase of anthranilate synthase
FIU99_06425	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FIU99_06435	COG0613	PHP domain protein
FIU99_06440	COG0009	L-threonylcarbamoyladenylate synthase
FIU99_06455	COG1187	pseudouridine synthase activity
FIU99_06460	COG0384	phenazine biosynthesis protein PhzF
FIU99_06470	COG2814	Major facilitator Superfamily
FIU99_06475	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FIU99_06480	COG4988	ABC transporter
FIU99_06485	COG0492	ferredoxin-NADP+ reductase activity
FIU99_06500	COG2175	clavaminate synthase activity
FIU99_06515	COG0612	Peptidase, M16
FIU99_06525	COG2949	membrane
FIU99_06535	COG0281	malic enzyme
FIU99_06540	COG1643	Atp-dependent helicase
FIU99_06555	COG1448	Aminotransferase
FIU99_06560	COG2770	Histidine kinase
FIU99_06560	COG3437	response regulator, receiver
FIU99_06570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU99_06585	COG0017	Asparaginyl-tRNA synthetase
FIU99_06605	COG0814	amino acid
FIU99_06615	COG1760	l-serine dehydratase
FIU99_06620	COG0814	amino acid
FIU99_06625	COG0494	nUDIX hydrolase
FIU99_06635	COG2205	protein histidine kinase activity
FIU99_06635	COG0784	Response regulator, receiver
FIU99_06655	COG3106	COG3106 Predicted ATPase
FIU99_06665	COG3283	Transcriptional regulator of aromatic amino acids metabolism
FIU99_06670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIU99_06690	COG3706	GGDEF domain
FIU99_06695	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIU99_06720	COG2989	Protein conserved in bacteria
FIU99_06725	COG3108	Peptidase M15
FIU99_06730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU99_06745	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIU99_06780	COG4667	esterase of the alpha-beta hydrolase superfamily
FIU99_06785	COG0783	Belongs to the Dps family
FIU99_06795	COG0531	amino acid
FIU99_06800	COG2962	Rard protein
FIU99_06860	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FIU99_06975	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIU99_07010	COG0546	phosphoglycolate phosphatase activity
FIU99_07015	COG4628	conserved protein (DUF2132)
FIU99_07025	COG0456	acetyltransferase
FIU99_07035	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FIU99_07045	COG0730	response to heat
FIU99_07055	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_07065	COG2824	Alkylphosphonate utilization operon protein PhnA
FIU99_07080	COG0456	acetyltransferase
FIU99_07100	COG3040	lipid binding
FIU99_07115	COG3122	Protein conserved in bacteria
FIU99_07175	COG0454	-acetyltransferase
FIU99_07180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIU99_07205	COG0456	acetyltransferase
FIU99_07225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIU99_07240	COG2195	Cleaves the N-terminal amino acid of tripeptides
FIU99_07250	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FIU99_07260	COG0625	glutathione transferase activity
FIU99_07275	COG2885	chlorophyll binding
FIU99_07290	COG0277	FAD linked oxidase domain protein
FIU99_07290	COG0247	lactate metabolic process
FIU99_07305	COG2986	histidine ammonia-lyase
FIU99_07315	COG0010	Belongs to the arginase family
FIU99_07320	COG1228	amidohydrolase
FIU99_07325	COG2188	Transcriptional regulator
FIU99_07330	COG4326	sporulation control protein
FIU99_07350	COG0500	methyltransferase
FIU99_07370	COG1346	cytolysis
FIU99_07380	COG2925	Exonuclease
FIU99_07390	COG0702	epimerase
FIU99_07395	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FIU99_07405	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FIU99_07415	COG0406	alpha-ribazole phosphatase activity
FIU99_07450	COG3706	GGDEF domain
FIU99_07460	COG2814	Major facilitator Superfamily
FIU99_07470	COG1119	ATPase activity
FIU99_07480	COG0784	Response regulator, receiver
FIU99_07480	COG5002	protein histidine kinase activity
FIU99_07490	COG1451	nucleotide metabolic process
FIU99_07505	COG3063	Type IV pilus biogenesis stability protein PilW
FIU99_07510	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIU99_07510	COG0596	Alpha beta hydrolase
FIU99_07530	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FIU99_07545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU99_07570	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FIU99_07575	COG0515	serine threonine protein kinase
FIU99_07675	COG3501	Rhs element vgr protein
FIU99_07690	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FIU99_07695	COG0372	Belongs to the citrate synthase family
FIU99_07705	COG2828	Protein conserved in bacteria
FIU99_07725	COG0561	phosphatase activity
FIU99_07730	COG0602	queuosine metabolic process
FIU99_07760	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FIU99_07765	COG0840	transmembrane signaling receptor activity
FIU99_07770	COG1254	Belongs to the acylphosphatase family
FIU99_07775	COG2920	part of a sulfur-relay system
FIU99_07780	COG0670	Belongs to the BI1 family
FIU99_07785	COG1126	abc transporter atp-binding protein
FIU99_07790	COG0765	amino acid transport
FIU99_07795	COG4597	amino acid ABC transporter
FIU99_07800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU99_07810	COG1666	GTP binding
FIU99_07815	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FIU99_07850	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FIU99_07850	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FIU99_07855	COG3008	intermembrane lipid transfer
FIU99_07860	COG2995	paraquat-inducible protein a
FIU99_07865	COG1132	(ABC) transporter
FIU99_07870	COG1956	GAF domain-containing protein
FIU99_07875	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FIU99_07890	COG0308	aminopeptidase N
FIU99_07905	COG0167	dihydroorotate dehydrogenase activity
FIU99_07915	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FIU99_07915	COG0116	Belongs to the methyltransferase superfamily
FIU99_07925	COG0488	(ABC) transporter
FIU99_07940	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FIU99_07945	COG1067	ATP-dependent peptidase activity
FIU99_08000	COG0789	Transcriptional regulator
FIU99_08035	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FIU99_08055	COG0840	transmembrane signaling receptor activity
FIU99_08190	COG3424	synthase
FIU99_08205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU99_08230	COG1132	(ABC) transporter
FIU99_08345	COG3278	Belongs to the heme-copper respiratory oxidase family
FIU99_08360	COG2010	Cytochrome c
FIU99_08370	COG2217	Heavy metal translocating P-type atpase
FIU99_08385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIU99_08390	COG0589	response to stress
FIU99_08415	COG3842	ATPase activity
FIU99_08420	COG1176	ABC-type spermidine putrescine transport system, permease component I
FIU99_08425	COG1177	transmembrane transport
FIU99_08430	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FIU99_08435	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FIU99_08440	COG2199	diguanylate cyclase activity
FIU99_08445	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FIU99_08450	COG0004	ammonium transporteR
FIU99_08465	COG0437	4 iron, 4 sulfur cluster binding
FIU99_08470	COG3383	formate dehydrogenase (NAD+) activity
FIU99_08470	COG0243	molybdopterin cofactor binding
FIU99_08500	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FIU99_08515	COG3038	cytochrome b561
FIU99_08540	COG0583	DNA-binding transcription factor activity
FIU99_08550	COG0583	DNA-binding transcription factor activity
FIU99_08555	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FIU99_08575	COG0069	glutamate synthase activity
FIU99_08580	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_08595	COG0488	(ABC) transporter
FIU99_08605	COG1595	DNA-templated transcription, initiation
FIU99_08620	COG3852	Histidine kinase
FIU99_08635	COG4662	Binding-protein-dependent transport system inner membrane component
FIU99_08640	COG3842	ATPase activity
FIU99_08645	COG0746	molybdenum cofactor guanylyltransferase activity
FIU99_08650	COG0303	'Molybdopterin
FIU99_08680	COG1940	carbohydrate kinase activity
FIU99_08695	COG0840	transmembrane signaling receptor activity
FIU99_08700	COG0791	NLP P60 protein
FIU99_08720	COG0307	riboflavin synthase, alpha
FIU99_08770	COG2204	response regulator
FIU99_08780	COG0438	transferase activity, transferring glycosyl groups
FIU99_08815	COG0297	glycogen (starch) synthase activity
FIU99_08825	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FIU99_08865	COG4774	siderophore transport
FIU99_08885	COG4615	Cyclic peptide transporter
FIU99_08895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FIU99_08900	COG1120	ATPase activity
FIU99_08905	COG2977	Belongs to the P-Pant transferase superfamily
FIU99_08910	COG1929	Belongs to the glycerate kinase type-1 family
FIU99_08915	COG3835	regulator
FIU99_08925	COG2814	Major facilitator Superfamily
FIU99_08935	COG1288	antiporter activity
FIU99_08945	COG2186	Transcriptional regulator
FIU99_08955	COG3713	MltA-interacting MipA family protein
FIU99_08965	COG0745	RESPONSE REGULATOR receiver
FIU99_08975	COG0583	DNA-binding transcription factor activity
FIU99_08995	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FIU99_09015	COG2116	formate transmembrane transporter activity
FIU99_09020	COG2146	nitrite reductase [NAD(P)H] activity
FIU99_09025	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIU99_09055	COG4565	transcriptional regulatory protein
FIU99_09060	COG3290	protein histidine kinase activity
FIU99_09080	COG0848	biopolymer transport protein
FIU99_09085	COG0811	peptide transport
FIU99_09090	COG0811	peptide transport
FIU99_09100	COG4774	siderophore transport
FIU99_09110	COG2205	protein histidine kinase activity
FIU99_09115	COG0745	RESPONSE REGULATOR receiver
FIU99_09120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU99_09160	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FIU99_09165	COG1328	CTP reductase activity
FIU99_09170	COG0840	transmembrane signaling receptor activity
FIU99_09180	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIU99_09190	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIU99_09195	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIU99_09200	COG0633	Ferredoxin
FIU99_09225	COG0019	diaminopimelate decarboxylase activity
FIU99_09270	COG1136	(ABC) transporter
FIU99_09275	COG0534	Mate efflux family protein
FIU99_09280	COG0702	epimerase
FIU99_09290	COG2814	Major facilitator Superfamily
FIU99_09300	COG1061	Type III restriction enzyme res subunit
FIU99_09315	COG2205	protein histidine kinase activity
FIU99_09340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU99_09345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU99_09365	COG0463	Glycosyl transferase, family 2
FIU99_09400	COG0455	bacterial-type flagellum organization
FIU99_09415	COG2188	Transcriptional regulator
FIU99_09420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU99_09420	COG1263	PTS System
FIU99_09425	COG1621	beta-fructofuranosidase activity
FIU99_09435	COG0583	DNA-binding transcription factor activity
FIU99_09440	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FIU99_09470	COG4221	oxidoreductase activity
FIU99_09505	COG0307	riboflavin synthase, alpha
FIU99_09555	COG0242	peptide deformylase activity
FIU99_09560	COG0519	Catalyzes the synthesis of GMP from XMP
FIU99_09575	COG4580	involved in the transport of maltose and maltodextrins
FIU99_09580	COG0778	Nitroreductase
FIU99_09635	COG5001	Diguanylate cyclase
FIU99_09635	COG3300	MHYT domain
FIU99_09665	COG1115	amino acid carrier protein
FIU99_09670	COG1280	lysine exporter protein (LysE YggA)
FIU99_09675	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FIU99_09680	COG0352	thiamine-phosphate diphosphorylase activity
FIU99_09685	COG0583	DNA-binding transcription factor activity
FIU99_09710	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU99_09720	COG1012	belongs to the aldehyde dehydrogenase family
FIU99_09730	COG0583	DNA-binding transcription factor activity
FIU99_09785	COG1609	Transcriptional regulator
FIU99_09800	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIU99_09805	COG1609	Transcriptional regulator
FIU99_09815	COG0642	Histidine kinase
FIU99_09820	COG0745	RESPONSE REGULATOR receiver
FIU99_09840	COG1858	cytochrome C peroxidase
FIU99_09855	COG2205	protein histidine kinase activity
FIU99_09855	COG0784	Response regulator, receiver
FIU99_09860	COG0488	(ABC) transporter
FIU99_09865	COG3437	response regulator, receiver
FIU99_09875	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FIU99_09885	COG2223	nitrite transmembrane transporter activity
FIU99_09890	COG1216	Glycosyl transferase, family 2
FIU99_09900	COG0673	inositol 2-dehydrogenase activity
FIU99_09905	COG3718	enzyme involved in inositol metabolism
FIU99_09930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU99_09935	COG0673	inositol 2-dehydrogenase activity
FIU99_09940	COG3962	Belongs to the TPP enzyme family
FIU99_09955	COG0477	Major facilitator Superfamily
FIU99_09955	COG2814	Major facilitator Superfamily
FIU99_09975	COG0183	Belongs to the thiolase family
FIU99_09980	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FIU99_10020	COG3962	Belongs to the TPP enzyme family
FIU99_10025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU99_10035	COG1129	ABC transporter
FIU99_10040	COG4211	Belongs to the binding-protein-dependent transport system permease family
FIU99_10050	COG0277	FAD linked oxidase domain protein
FIU99_10060	COG0583	DNA-binding transcription factor activity
FIU99_10080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU99_10085	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FIU99_10105	COG1621	beta-fructofuranosidase activity
FIU99_10120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU99_10120	COG1263	PTS System
FIU99_10130	COG1335	isochorismatase
FIU99_10135	COG1741	Belongs to the pirin family
FIU99_10175	COG4974	Belongs to the 'phage' integrase family
FIU99_10185	COG1733	regulation of RNA biosynthetic process
FIU99_10195	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FIU99_10215	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FIU99_10220	COG0072	phenylalanine-tRNA ligase activity
FIU99_10220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIU99_10230	COG3706	GGDEF domain
FIU99_10255	COG2133	pyrroloquinoline quinone binding
FIU99_10265	COG1902	pentaerythritol trinitrate reductase activity
FIU99_10295	COG0322	excinuclease ABC activity
FIU99_10300	COG2197	response regulator
FIU99_10315	COG0417	DNA replication proofreading
FIU99_10330	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FIU99_10335	COG3099	Belongs to the UPF0263 family
FIU99_10370	COG1607	acyl-coa hydrolase
FIU99_10375	COG2350	Protein conserved in bacteria
FIU99_10390	COG3313	Fe-S protein
FIU99_10400	COG4134	Bacterial extracellular solute-binding protein
FIU99_10405	COG4135	transport system, permease component
FIU99_10410	COG4136	ATPase activity
FIU99_10415	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FIU99_10425	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FIU99_10430	COG0564	pseudouridine synthase activity
FIU99_10435	COG0733	neurotransmitter:sodium symporter activity
FIU99_10445	COG0626	cystathionine gamma-synthase activity
FIU99_10450	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FIU99_10455	COG5380	lipid catabolic process
FIU99_10460	COG2818	Glycosylase
FIU99_10475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU99_10480	COG1983	PspC domain protein
FIU99_10490	COG1842	Phage shock protein A
FIU99_10495	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FIU99_10505	COG4168	peptide transport system, permease
FIU99_10510	COG4171	peptide transport system, permease
FIU99_10520	COG4172	Belongs to the ABC transporter superfamily
FIU99_10535	COG1227	inorganic diphosphatase activity
FIU99_10545	COG0217	transcriptional regulatory protein
FIU99_10550	COG0140	phosphoribosyl-ATP diphosphatase activity
FIU99_10550	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FIU99_10555	COG0107	imidazoleglycerol-phosphate synthase activity
FIU99_10560	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FIU99_10565	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FIU99_10570	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FIU99_10570	COG0131	Imidazoleglycerol-phosphate dehydratase
FIU99_10580	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FIU99_10590	COG1757	Na H antiporter
FIU99_10600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU99_10610	COG0482	sulfurtransferase activity
FIU99_10620	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FIU99_10630	COG2268	Band 7 protein
FIU99_10640	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIU99_10655	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_10675	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FIU99_10680	COG1073	alpha beta
FIU99_10680	COG2226	methyltransferase
FIU99_10685	COG0156	8-amino-7-oxononanoate synthase activity
FIU99_10695	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIU99_10710	COG1199	ATP-dependent helicase activity
FIU99_10715	COG0730	response to heat
FIU99_10730	COG2850	peptidyl-arginine hydroxylation
FIU99_10735	COG0840	transmembrane signaling receptor activity
FIU99_10740	COG0708	Exodeoxyribonuclease III
FIU99_10745	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FIU99_10750	COG1960	acyl-CoA dehydrogenase activity
FIU99_10770	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FIU99_10775	COG0463	Glycosyl transferase, family 2
FIU99_10780	COG0745	RESPONSE REGULATOR receiver
FIU99_10785	COG5002	protein histidine kinase activity
FIU99_10785	COG3850	Histidine kinase
FIU99_10800	COG1940	carbohydrate kinase activity
FIU99_10815	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FIU99_10820	COG1881	PFAM PEBP family protein
FIU99_10825	COG1902	pentaerythritol trinitrate reductase activity
FIU99_10845	COG5002	protein histidine kinase activity
FIU99_10845	COG0784	Response regulator, receiver
FIU99_10865	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FIU99_10870	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FIU99_10875	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FIU99_10880	COG2885	chlorophyll binding
FIU99_10900	COG0811	peptide transport
FIU99_10905	COG0824	Thioesterase
FIU99_10915	COG4890	Cyd operon protein YbgT
FIU99_10920	COG1294	oxidase, subunit
FIU99_10925	COG1271	oxidase subunit
FIU99_10930	COG2255	four-way junction helicase activity
FIU99_10935	COG0632	four-way junction helicase activity
FIU99_10940	COG0840	transmembrane signaling receptor activity
FIU99_10945	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FIU99_10965	COG4221	oxidoreductase activity
FIU99_10980	COG0243	molybdopterin cofactor binding
FIU99_10985	COG3005	denitrification pathway
FIU99_10990	COG4459	periplasmic nitrate reductase
FIU99_10995	COG0390	transport system, permease component
FIU99_11005	COG2116	formate transmembrane transporter activity
FIU99_11030	COG0542	response to heat
FIU99_11035	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FIU99_11040	COG1278	Cold shock
FIU99_11050	COG1187	pseudouridine synthase activity
FIU99_11060	COG1801	Protein of unknown function DUF72
FIU99_11070	COG0500	methyltransferase
FIU99_11075	COG0189	ligase activity
FIU99_11075	COG4067	protein conserved in archaea
FIU99_11105	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FIU99_11110	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FIU99_11120	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIU99_11125	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FIU99_11130	COG0745	RESPONSE REGULATOR receiver
FIU99_11145	COG3070	regulator of competence-specific genes
FIU99_11170	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FIU99_11175	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FIU99_11200	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FIU99_11205	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FIU99_11210	COG1435	thymidine kinase activity
FIU99_11215	COG0215	cysteine-tRNA ligase activity
FIU99_11220	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FIU99_11230	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FIU99_11235	COG3012	SEC-C Motif Domain Protein
FIU99_11240	COG3139	Protein of unknown function (DUF1315)
FIU99_11250	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU99_11265	COG0840	transmembrane signaling receptor activity
FIU99_11270	COG2226	methyltransferase
FIU99_11285	COG1785	Belongs to the alkaline phosphatase family
FIU99_11305	COG0668	transmembrane transport
FIU99_11310	COG2983	Belongs to the UPF0260 family
FIU99_11325	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FIU99_11330	COG0583	DNA-binding transcription factor activity
FIU99_11335	COG2951	lytic endotransglycosylase activity
FIU99_11340	COG3100	YcgL domain-containing protein
FIU99_11345	COG0850	regulation of cytokinetic process
FIU99_11350	COG2894	cell division
FIU99_11360	COG1012	belongs to the aldehyde dehydrogenase family
FIU99_11360	COG1454	alcohol dehydrogenase
FIU99_11365	COG2095	MarC family integral membrane protein
FIU99_11370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIU99_11375	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FIU99_11380	COG1757	Na H antiporter
FIU99_11405	COG3082	Protein of unknown function (DUF1414)
FIU99_11410	COG3083	sulfuric ester hydrolase activity
FIU99_11445	COG3852	Histidine kinase
FIU99_11475	COG0123	including yeast histone deacetylase and acetoin utilization protein
FIU99_11485	COG1881	PFAM PEBP family protein
FIU99_11495	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FIU99_11500	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FIU99_11520	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FIU99_11525	COG0302	gtp cyclohydrolase
FIU99_11525	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FIU99_11530	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FIU99_11535	COG0302	gtp cyclohydrolase
FIU99_11545	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FIU99_11550	COG0110	maltose O-acetyltransferase activity
FIU99_11600	COG2982	Protein involved in outer membrane biogenesis
FIU99_11605	COG0572	uridine kinase
FIU99_11610	COG0489	protein tyrosine kinase activity
FIU99_11655	COG0517	IMP dehydrogenase activity
FIU99_11665	COG3706	GGDEF domain
FIU99_11670	COG0314	molybdopterin synthase activity
FIU99_11675	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FIU99_11680	COG0315	cyclic pyranopterin monophosphate synthase activity
FIU99_11685	COG0521	Mo-molybdopterin cofactor biosynthetic process
FIU99_11690	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FIU99_11695	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FIU99_11700	COG2198	Histidine kinase
FIU99_11715	COG0556	nucleotide-excision repair
FIU99_11730	COG0739	heme binding
FIU99_11755	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FIU99_11770	COG2204	response regulator
FIU99_11775	COG2885	chlorophyll binding
FIU99_11795	COG1987	bacterial-type flagellum assembly
FIU99_11805	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FIU99_11820	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FIU99_11825	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FIU99_11830	COG1516	flagellar protein fliS
FIU99_11845	COG1580	Controls the rotational direction of flagella during chemotaxis
FIU99_11850	COG1191	sigma factor activity
FIU99_11855	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FIU99_11860	COG1360	Flagellar Motor Protein
FIU99_11890	COG1706	bacterial-type flagellum-dependent cell motility
FIU99_11895	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FIU99_11900	COG4786	Flagellar basal body rod
FIU99_11905	COG4787	bacterial-type flagellum-dependent cell motility
FIU99_11910	COG1749	Flagellar hook protein flgE
FIU99_11915	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FIU99_11920	COG1558	bacterial-type flagellum-dependent cell motility
FIU99_11925	COG1815	bacterial-type flagellum-dependent cell motility
FIU99_11945	COG0741	lytic transglycosylase activity
FIU99_11945	COG1388	LysM domain
FIU99_11950	COG4657	Part of a membrane complex involved in electron transport
FIU99_11960	COG4656	Part of a membrane complex involved in electron transport
FIU99_11965	COG4658	electron transport chain
FIU99_11980	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FIU99_11985	COG0346	lactoylglutathione lyase activity
FIU99_12005	COG2056	Na+-H+ antiporter family
FIU99_12015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIU99_12020	COG2716	regulation of RNA biosynthetic process
FIU99_12025	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FIU99_12045	COG4783	chaperone-mediated protein folding
FIU99_12050	COG1393	Belongs to the ArsC family
FIU99_12075	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FIU99_12090	COG2912	Transglutaminase-like superfamily
FIU99_12100	COG2890	protein-(glutamine-N5) methyltransferase activity
FIU99_12125	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FIU99_12135	COG0012	GTP binding
FIU99_12255	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FIU99_12265	COG3951	Flagellar rod assembly protein muramidase FlgJ
FIU99_12265	COG1705	Flagellar rod assembly protein muramidase FlgJ
FIU99_12270	COG1706	bacterial-type flagellum-dependent cell motility
FIU99_12275	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FIU99_12280	COG4786	Flagellar basal body rod
FIU99_12285	COG4787	bacterial-type flagellum-dependent cell motility
FIU99_12290	COG1749	Flagellar hook protein flgE
FIU99_12295	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FIU99_12300	COG1558	bacterial-type flagellum-dependent cell motility
FIU99_12305	COG1815	bacterial-type flagellum-dependent cell motility
FIU99_12310	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FIU99_12315	COG0835	chemotaxis
FIU99_12315	COG0784	Response regulator, receiver
FIU99_12325	COG2747	anti-sigma28 factor FlgM
FIU99_12365	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FIU99_12375	COG2194	sulfuric ester hydrolase activity
FIU99_12395	COG2885	chlorophyll binding
FIU99_12395	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FIU99_12415	COG2217	Heavy metal translocating P-type atpase
FIU99_12415	COG2608	mercury ion transmembrane transporter activity
FIU99_12435	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FIU99_12445	COG0326	Molecular chaperone. Has ATPase activity
FIU99_12450	COG3710	Transcriptional regulator
FIU99_12470	COG0622	Phosphoesterase
FIU99_12495	COG1090	epimerase
FIU99_12500	COG0300	oxidoreductase activity
FIU99_12505	COG3118	belongs to the thioredoxin family
FIU99_12510	COG0330	HflC and HflK could
FIU99_12540	COG3115	cell septum assembly
FIU99_12545	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FIU99_12550	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FIU99_12555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU99_12565	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FIU99_12570	COG2190	(PTS) system
FIU99_12575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU99_12585	COG1702	phosphate starvation-inducible protein PhoH
FIU99_12590	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FIU99_12595	COG4535	Mg2 and Co2 transporter CorC
FIU99_12600	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FIU99_12605	COG2888	peptidyl-tyrosine sulfation
FIU99_12610	COG0495	leucyl-tRNA aminoacylation
FIU99_12615	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FIU99_12620	COG1466	dna polymerase III delta subunit
FIU99_12625	COG0799	negative regulation of ribosome biogenesis
FIU99_12630	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FIU99_12635	COG0768	penicillin binding
FIU99_12640	COG0772	Belongs to the SEDS family
FIU99_12645	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FIU99_12650	COG1686	Belongs to the peptidase S11 family
FIU99_12665	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FIU99_12680	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FIU99_12690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU99_12695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU99_12720	COG0366	Alpha amylase catalytic
FIU99_12725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU99_12725	COG1263	PTS System
FIU99_12730	COG1609	Transcriptional regulator
FIU99_12740	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FIU99_12745	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FIU99_12750	COG2011	ABC-type metal ion transport system permease component
FIU99_12755	COG1464	Belongs to the NlpA lipoprotein family
FIU99_12770	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FIU99_12780	COG1720	tRNA m6t6A37 methyltransferase activity
FIU99_12790	COG0121	glutamine amidotransferase
FIU99_12795	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FIU99_12800	COG1960	acyl-CoA dehydrogenase activity
FIU99_12810	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FIU99_12820	COG2226	methyltransferase
FIU99_12830	COG0741	lytic transglycosylase activity
FIU99_12830	COG1388	LysM domain
FIU99_12845	COG0347	Belongs to the P(II) protein family
FIU99_12860	COG0825	malonyl-CoA metabolic process
FIU99_12865	COG0587	DNA-directed DNA polymerase activity
FIU99_12870	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FIU99_12890	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIU99_12895	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FIU99_12900	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU99_12905	COG0750	zinc metalloprotease
FIU99_12915	COG0575	Belongs to the CDS family
FIU99_12920	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FIU99_12925	COG0233	cytoplasmic translational termination
FIU99_12930	COG0528	UMP kinase activity
FIU99_12940	COG0052	Belongs to the universal ribosomal protein uS2 family
FIU99_12950	COG0024	Methionine aminopeptidase
FIU99_12965	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FIU99_12970	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FIU99_12995	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIU99_12995	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIU99_13000	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FIU99_13005	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FIU99_13010	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FIU99_13025	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FIU99_13030	COG2252	PERMEase
FIU99_13035	COG2195	Cleaves the N-terminal amino acid of tripeptides
FIU99_13040	COG0189	ligase activity
FIU99_13040	COG4067	protein conserved in archaea
FIU99_13045	COG0189	ligase activity
FIU99_13055	COG0733	neurotransmitter:sodium symporter activity
FIU99_13070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FIU99_13080	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FIU99_13085	COG0745	RESPONSE REGULATOR receiver
FIU99_13085	COG3706	GGDEF domain
FIU99_13095	COG1477	protein flavinylation
FIU99_13100	COG2871	sodium ion transport
FIU99_13105	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FIU99_13120	COG1805	sodium ion transport
FIU99_13125	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FIU99_13130	COG0271	Belongs to the BolA IbaG family
FIU99_13135	COG2813	Specifically methylates the guanine in position
FIU99_13145	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FIU99_13160	COG1595	DNA-templated transcription, initiation
FIU99_13175	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FIU99_13180	COG0693	protein deglycase activity
FIU99_13185	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FIU99_13190	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FIU99_13200	COG0560	Phosphoserine phosphatase
FIU99_13210	COG0813	purine-nucleoside phosphorylase activity
FIU99_13215	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FIU99_13220	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FIU99_13235	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FIU99_13240	COG0084	hydrolase, TatD family'
FIU99_13250	COG3022	response to hydroperoxide
FIU99_13255	COG1115	amino acid carrier protein
FIU99_13290	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FIU99_13320	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FIU99_13325	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FIU99_13335	COG0583	DNA-binding transcription factor activity
FIU99_13340	COG0730	response to heat
FIU99_13345	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FIU99_13350	COG0505	Belongs to the CarA family
FIU99_13360	COG0494	nUDIX hydrolase
FIU99_13365	COG0653	protein targeting
FIU99_13370	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FIU99_13375	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FIU99_13380	COG0849	cell division
FIU99_13385	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FIU99_13400	COG0772	Belongs to the SEDS family
FIU99_13405	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FIU99_13410	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FIU99_13415	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FIU99_13425	COG0768	penicillin binding
FIU99_13430	COG3116	cell division
FIU99_13450	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FIU99_13455	COG3107	peptidoglycan biosynthetic process
FIU99_13465	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FIU99_13475	COG2969	positive regulation of protein catabolic process
FIU99_13480	COG0625	glutathione transferase activity
FIU99_13485	COG2857	Cytochrome c1
FIU99_13490	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FIU99_13495	COG0723	plastoquinol--plastocyanin reductase activity
FIU99_13510	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FIU99_13515	COG3105	Protein conserved in bacteria
FIU99_13520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIU99_13525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIU99_13535	COG0187	DNA topoisomerase II activity
FIU99_13540	COG3150	esterase
FIU99_13550	COG3151	Protein conserved in bacteria
FIU99_13555	COG0494	nUDIX hydrolase
FIU99_13560	COG1538	Outer membrane efflux protein
FIU99_13570	COG5002	protein histidine kinase activity
FIU99_13570	COG2198	Histidine kinase
FIU99_13570	COG0784	Response regulator, receiver
FIU99_13575	COG2203	Gaf domain
FIU99_13575	COG4251	negative regulation of phosphorylation
FIU99_13575	COG5001	Diguanylate cyclase
FIU99_13575	COG3706	GGDEF domain
FIU99_13580	COG1242	4 iron, 4 sulfur cluster binding
FIU99_13585	COG0067	glutamate synthase
FIU99_13585	COG0070	glutamate synthase
FIU99_13585	COG0069	glutamate synthase activity
FIU99_13595	COG0070	glutamate synthase
FIU99_13595	COG0067	glutamate synthase
FIU99_13595	COG0069	glutamate synthase activity
FIU99_13600	COG0493	'glutamate synthase
FIU99_13625	COG0195	Participates in both transcription termination and antitermination
FIU99_13630	COG0779	Required for maturation of 30S ribosomal subunits
FIU99_13645	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FIU99_13650	COG3153	acetyltransferase
FIU99_13675	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FIU99_13680	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FIU99_13695	COG0513	Belongs to the DEAD box helicase family
FIU99_13725	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FIU99_13730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FIU99_13735	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FIU99_13740	COG1534	Rna-binding protein
FIU99_13745	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FIU99_13750	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FIU99_13755	COG2027	D-alanyl-D-alanine carboxypeptidase
FIU99_13765	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FIU99_13770	COG0739	heme binding
FIU99_13795	COG0628	permease
FIU99_13800	COG2813	Specifically methylates the guanine in position
FIU99_13810	COG0747	negative chemotaxis
FIU99_13825	COG0444	Belongs to the ABC transporter superfamily
FIU99_13830	COG4608	Belongs to the ABC transporter superfamily
FIU99_13840	COG2971	BadF BadG BcrA BcrD
FIU99_13855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIU99_13860	COG3842	ATPase activity
FIU99_13870	COG1840	ABC-type Fe3 transport system, periplasmic component
FIU99_13875	COG0004	ammonium transporteR
FIU99_13890	COG1049	propionate catabolic process, 2-methylcitrate cycle
FIU99_13895	COG1752	Esterase of the alpha-beta hydrolase superfamily
FIU99_13900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FIU99_13905	COG1643	Atp-dependent helicase
FIU99_13915	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FIU99_13930	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FIU99_13945	COG0842	Transport permease protein
FIU99_13950	COG1131	(ABC) transporter
FIU99_13955	COG0659	secondary active sulfate transmembrane transporter activity
FIU99_13960	COG0288	reversible hydration of carbon dioxide
FIU99_13975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIU99_13980	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIU99_13985	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FIU99_13990	COG2186	Transcriptional regulator
FIU99_13995	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FIU99_14000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIU99_14010	COG0716	FMN binding
FIU99_14015	COG3023	N-Acetylmuramoyl-L-alanine amidase
FIU99_14020	COG0157	Belongs to the NadC ModD family
FIU99_14025	COG4969	Belongs to the N-Me-Phe pilin family
FIU99_14030	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FIU99_14035	COG1459	type II secretion system
FIU99_14045	COG0237	dephospho-CoA kinase activity
FIU99_14050	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FIU99_14055	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FIU99_14065	COG0336	Belongs to the RNA methyltransferase TrmD family
FIU99_14075	COG0228	four-way junction DNA binding
FIU99_14080	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FIU99_14085	COG4137	Cytochrome C assembly protein
FIU99_14090	COG4536	flavin adenine dinucleotide binding
FIU99_14095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FIU99_14100	COG1388	LysM domain
FIU99_14100	COG4942	peptidase
FIU99_14110	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FIU99_14115	COG0585	pseudouridine synthase activity
FIU99_14125	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FIU99_14130	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FIU99_14140	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FIU99_14145	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FIU99_14150	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FIU99_14155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FIU99_14160	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FIU99_14165	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FIU99_14170	COG1610	YqeY-like protein
FIU99_14175	COG0358	DNA primase activity
FIU99_14180	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FIU99_14190	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FIU99_14195	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FIU99_14200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIU99_14205	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FIU99_14220	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FIU99_14230	COG3610	response to peptide
FIU99_14235	COG2966	Psort location CytoplasmicMembrane, score
FIU99_14240	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FIU99_14245	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FIU99_14250	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FIU99_14255	COG0142	geranyltranstransferase activity
FIU99_14265	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIU99_14275	COG2213	PTS system mannitol-specific
FIU99_14275	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU99_14285	COG3722	fumarate hydratase activity
FIU99_14290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIU99_14295	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FIU99_14300	COG1349	DNA-binding transcription factor activity
FIU99_14305	COG0469	pyruvate kinase activity
FIU99_14315	COG3706	GGDEF domain
FIU99_14325	COG0583	DNA-binding transcription factor activity
FIU99_14340	COG0668	transmembrane transport
FIU99_14345	COG0191	fructose-bisphosphate aldolase activity
FIU99_14360	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FIU99_14365	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FIU99_14375	COG3091	SprT-like family
FIU99_14380	COG2356	endonuclease I
FIU99_14385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FIU99_14390	COG0189	ligase activity
FIU99_14400	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FIU99_14415	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FIU99_14420	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FIU99_14425	COG0762	integral membrane protein
FIU99_14575	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FIU99_14580	COG2066	Belongs to the glutaminase family
FIU99_14585	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FIU99_14595	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FIU99_14650	COG0312	modulator of DNA gyrase
FIU99_14655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU99_14660	COG3164	Protein of unknown function
FIU99_14665	COG1530	ribonuclease E activity
FIU99_14670	COG0424	maF-like protein
FIU99_14675	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FIU99_14680	COG1792	Involved in formation and maintenance of cell shape
FIU99_14685	COG1077	Cell shape determining protein MreB Mrl
FIU99_14730	COG1459	type II secretion system
FIU99_14735	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FIU99_14745	COG3409	Peptidoglycan-binding domain 1 protein
FIU99_14745	COG3267	Type II secretory pathway component ExeA
FIU99_14770	COG2199	diguanylate cyclase activity
FIU99_14770	COG2200	EAL domain
FIU99_14775	COG0629	single-stranded DNA binding
FIU99_14790	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FIU99_14800	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FIU99_14805	COG0527	aspartate kinase activity
FIU99_14810	COG0312	modulator of DNA gyrase
FIU99_14815	COG3028	Belongs to the UPF0307 family
FIU99_14820	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FIU99_14825	COG1178	ABC-type Fe3 transport system permease component
FIU99_14830	COG4143	(ABC) transporter
FIU99_14835	COG0163	prenyltransferase activity
FIU99_14840	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FIU99_14855	COG2105	PFAM AIG2 family protein
FIU99_14860	COG2911	Protein conserved in bacteria
FIU99_14865	COG0729	surface antigen
FIU99_14870	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU99_14880	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FIU99_14890	COG1136	(ABC) transporter
FIU99_14920	COG0432	Pfam Uncharacterised protein family UPF0047
FIU99_15015	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FIU99_15020	COG0305	Participates in initiation and elongation during chromosome replication
FIU99_15040	COG0360	Binds together with S18 to 16S ribosomal RNA
FIU99_15050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FIU99_15055	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FIU99_15060	COG0049	tRNA binding
FIU99_15070	COG2168	tRNA wobble position uridine thiolation
FIU99_15075	COG2923	Belongs to the DsrF TusC family
FIU99_15085	COG2964	Protein conserved in bacteria
FIU99_15090	COG0545	Peptidyl-prolyl cis-trans isomerase
FIU99_15105	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FIU99_15110	COG0330	HflC and HflK could
FIU99_15115	COG0330	HflC and HflK could
FIU99_15120	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FIU99_15135	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FIU99_15145	COG0802	atpase or kinase
FIU99_15150	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FIU99_15205	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FIU99_15210	COG1162	GTPase activity
FIU99_15215	COG0688	phosphatidylethanolamine metabolic process
FIU99_15220	COG0490	domain, Protein
FIU99_15220	COG0471	metal ion transport
FIU99_15225	COG0840	transmembrane signaling receptor activity
FIU99_15235	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FIU99_15240	COG4942	peptidase
FIU99_15260	COG2816	NAD+ diphosphatase activity
FIU99_15265	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FIU99_15275	COG0085	RNA polymerase activity
FIU99_15285	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FIU99_15300	COG0250	Participates in transcription elongation, termination and antitermination
FIU99_15305	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FIU99_15315	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FIU99_15340	COG1072	(Pantothenic acid kinase))
FIU99_15355	COG0149	triose-phosphate isomerase activity
FIU99_15360	COG0534	Mate efflux family protein
FIU99_15365	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FIU99_15370	COG1575	Belongs to the MenA family. Type 1 subfamily
FIU99_15375	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FIU99_15380	COG1509	lysine 2,3-aminomutase activity
FIU99_15390	COG1285	pathogenesis
FIU99_15395	COG0205	6-phosphofructokinase activity
FIU99_15405	COG3678	ATP-independent chaperone mediated protein folding
FIU99_15410	COG0745	RESPONSE REGULATOR receiver
FIU99_15415	COG2205	protein histidine kinase activity
FIU99_15420	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FIU99_15425	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FIU99_15430	COG0180	Tryptophanyl-tRNA synthetase
FIU99_15435	COG0546	phosphoglycolate phosphatase activity
FIU99_15440	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FIU99_15445	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FIU99_15490	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FIU99_15500	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FIU99_15500	COG0678	peroxiredoxin activity
FIU99_15510	COG0251	oxidation-reduction process
FIU99_15515	COG0165	Argininosuccinate lyase
FIU99_15515	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FIU99_15520	COG0137	argininosuccinate synthase activity
FIU99_15530	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FIU99_15630	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FIU99_15640	COG4206	TonB-dependent receptor
FIU99_15665	COG0534	Mate efflux family protein
FIU99_15675	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FIU99_15680	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FIU99_15690	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FIU99_15695	COG3161	chorismate lyase activity
FIU99_15700	COG1580	Controls the rotational direction of flagella during chemotaxis
FIU99_15710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIU99_15715	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FIU99_15720	COG2177	Part of the ABC transporter FtsEX involved in
FIU99_15725	COG2884	Cell division ATP-binding protein ftsE
FIU99_15730	COG0552	protein localization to endoplasmic reticulum
FIU99_15735	COG0742	ribosomal rna small subunit methyltransferase
FIU99_15745	COG2095	MarC family integral membrane protein
FIU99_15790	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FIU99_15795	COG0640	Transcriptional regulator
FIU99_15800	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FIU99_15805	COG1280	lysine exporter protein (LysE YggA)
FIU99_15815	COG0561	phosphatase activity
FIU99_15835	COG2199	diguanylate cyclase activity
FIU99_15835	COG3287	FIST C domain
FIU99_15835	COG2200	EAL domain
FIU99_15840	COG1011	Hydrolase
FIU99_15845	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FIU99_15855	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FIU99_15860	COG0019	diaminopimelate decarboxylase activity
FIU99_15865	COG1965	Belongs to the frataxin family
FIU99_15870	COG3072	Adenylate cyclase
FIU99_15880	COG1587	Uroporphyrinogen-III synthase
FIU99_15885	COG2959	enzyme of heme biosynthesis
FIU99_15890	COG3071	HemY protein
FIU99_15950	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FIU99_15960	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FIU99_15965	COG3118	belongs to the thioredoxin family
FIU99_15975	COG0248	Ppx GppA phosphatase
FIU99_15980	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FIU99_15990	COG0514	ATP-dependent DNA helicase (RecQ)
FIU99_15995	COG2962	Rard protein
FIU99_16005	COG1280	lysine exporter protein (LysE YggA)
FIU99_16010	COG0405	Gamma-glutamyltransferase
FIU99_16030	COG0210	DNA helicase
FIU99_16045	COG3220	belongs to the UPF0276 family
FIU99_16065	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FIU99_16070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIU99_16085	COG1773	rubredoxin
FIU99_16100	COG0367	asparagine synthase
FIU99_16105	COG0477	Major facilitator Superfamily
FIU99_16130	COG0745	RESPONSE REGULATOR receiver
FIU99_16145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU99_16155	COG0747	negative chemotaxis
FIU99_16200	COG1309	transcriptional regulator
FIU99_16205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU99_16210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU99_16215	COG2960	long-chain fatty acid transporting porin activity
FIU99_16225	COG0583	DNA-binding transcription factor activity
FIU99_16230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FIU99_16255	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FIU99_16265	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIU99_16265	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIU99_16280	COG1943	Transposase
FIU99_16290	COG0084	hydrolase, TatD family'
FIU99_16295	COG0805	protein transport
FIU99_16325	COG1322	Protein conserved in bacteria
FIU99_16335	COG1639	'signal transduction protein
FIU99_16365	COG2081	HI0933 family
FIU99_16375	COG1528	Iron-storage protein
FIU99_16380	COG0589	response to stress
FIU99_16385	COG0697	spore germination
FIU99_16395	COG0742	ribosomal rna small subunit methyltransferase
FIU99_16400	COG5001	Diguanylate cyclase
FIU99_16400	COG5002	protein histidine kinase activity
FIU99_16405	COG1522	sequence-specific DNA binding
FIU99_16410	COG1943	Transposase
FIU99_16430	COG0006	proline dipeptidase activity
FIU99_16430	COG0006	proline dipeptidase activity
FIU99_16440	COG2022	thiamine diphosphate biosynthetic process
FIU99_16450	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FIU99_16455	COG0352	thiamine-phosphate diphosphorylase activity
FIU99_16470	COG2132	Multicopper oxidase
FIU99_16525	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIU99_16530	COG1739	Uncharacterized protein family UPF0029
FIU99_16540	COG0183	Belongs to the thiolase family
FIU99_16545	COG3706	GGDEF domain
FIU99_16550	COG0583	DNA-binding transcription factor activity
FIU99_16555	COG2814	Major facilitator Superfamily
FIU99_16565	COG0765	amino acid transport
FIU99_16575	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FIU99_16580	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FIU99_16585	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FIU99_16590	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FIU99_16595	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FIU99_16615	COG3312	ion transport
FIU99_16620	COG1475	DNA binding
FIU99_16625	COG1192	Involved in chromosome partitioning
FIU99_16635	COG0445	tRNA wobble uridine modification
FIU99_16640	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FIU99_16645	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FIU99_16650	COG0706	membrane insertase activity
FIU99_16665	COG1126	abc transporter atp-binding protein
FIU99_16715	COG3501	Rhs element vgr protein
FIU99_16740	COG0515	serine threonine protein kinase
FIU99_16740	COG2815	serine threonine protein kinase
FIU99_16775	COG1522	sequence-specific DNA binding
FIU99_16815	COG3250	beta-galactosidase activity
FIU99_16820	COG2211	Major facilitator Superfamily
FIU99_16835	COG1609	Transcriptional regulator
FIU99_16840	COG1309	transcriptional regulator
FIU99_16845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU99_16850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU99_16865	COG0183	Belongs to the thiolase family
FIU99_16880	COG1794	racemase activity, acting on amino acids and derivatives
FIU99_16885	COG2814	Major facilitator Superfamily
FIU99_16890	COG3240	lipase activity
FIU99_16895	COG4412	M6 family metalloprotease domain protein
FIU99_16895	COG3291	Pkd domain containing protein
FIU99_16940	COG1328	CTP reductase activity
FIU99_16945	COG0602	queuosine metabolic process
FIU99_16955	COG4067	protein conserved in archaea
FIU99_16955	COG0189	ligase activity
FIU99_16965	COG0545	Peptidyl-prolyl cis-trans isomerase
FIU99_16985	COG0247	lactate metabolic process
FIU99_16990	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
FIU99_16995	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FIU99_17000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FIU99_17005	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FIU99_17030	COG2827	Endonuclease containing a URI domain
FIU99_17045	COG5002	protein histidine kinase activity
FIU99_17045	COG0784	Response regulator, receiver
FIU99_17075	COG1289	transmembrane transporter activity
FIU99_17080	COG0210	DNA helicase
FIU99_17100	COG0484	heat shock protein binding
FIU99_17110	COG3300	MHYT domain
FIU99_17110	COG5001	Diguanylate cyclase
FIU99_17115	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FIU99_17125	COG4181	ATPase activity
FIU99_17130	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FIU99_17135	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FIU99_17140	COG1984	allophanate hydrolase subunit 2
FIU99_17150	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FIU99_17155	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FIU99_17165	COG3005	denitrification pathway
FIU99_17175	COG0243	molybdopterin cofactor binding
FIU99_17185	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FIU99_17190	COG3850	Histidine kinase
FIU99_17195	COG2197	response regulator
FIU99_17200	COG3069	C4-dicarboxylate transmembrane transporter activity
FIU99_17220	COG3038	cytochrome b561
FIU99_17225	COG2353	YceI-like domain
FIU99_17230	COG2116	formate transmembrane transporter activity
FIU99_17235	COG0583	DNA-binding transcription factor activity
FIU99_17245	COG3593	DNA synthesis involved in DNA repair
FIU99_17250	COG0737	Belongs to the 5'-nucleotidase family
FIU99_17285	COG1605	Chorismate mutase
FIU99_17300	COG0745	RESPONSE REGULATOR receiver
FIU99_17305	COG0784	Response regulator, receiver
FIU99_17305	COG2205	protein histidine kinase activity
FIU99_17310	COG0840	transmembrane signaling receptor activity
FIU99_17315	COG3070	regulator of competence-specific genes
FIU99_17320	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FIU99_17335	COG4783	chaperone-mediated protein folding
FIU99_17340	COG2050	protein possibly involved in aromatic compounds catabolism
FIU99_17350	COG4533	DNA binding
FIU99_17360	COG4771	TonB-dependent receptor
FIU99_17360	COG1629	transport
FIU99_17365	COG0583	DNA-binding transcription factor activity
FIU99_17370	COG0045	succinate-CoA ligase (ADP-forming) activity
FIU99_17370	COG1042	CoA-binding domain protein
FIU99_17370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIU99_17375	COG3266	domain, Protein
FIU99_17380	COG1181	Belongs to the D-alanine--D-alanine ligase family
FIU99_17400	COG0023	Translation Initiation Factor
FIU99_17430	COG0745	RESPONSE REGULATOR receiver
FIU99_17440	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FIU99_17445	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FIU99_17460	COG3706	GGDEF domain
FIU99_17465	COG2203	Gaf domain
FIU99_17465	COG3706	GGDEF domain
FIU99_17465	COG5001	Diguanylate cyclase
FIU99_17465	COG4251	negative regulation of phosphorylation
FIU99_17475	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FIU99_17480	COG4149	molybdate abc transporter
FIU99_17485	COG0725	ABC transporter, periplasmic molybdate-binding protein
FIU99_17505	COG1609	Transcriptional regulator
FIU99_17510	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU99_17510	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU99_17515	COG1105	Belongs to the carbohydrate kinase PfkB family
FIU99_17520	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FIU99_17520	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU99_17520	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU99_17525	COG3706	GGDEF domain
FIU99_17530	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FIU99_17535	COG2207	Transcriptional regulator
FIU99_17540	COG1979	alcohol dehydrogenase
FIU99_17555	COG2205	protein histidine kinase activity
FIU99_17555	COG2198	Histidine kinase
FIU99_17555	COG0784	Response regulator, receiver
FIU99_17560	COG1879	ABC-type sugar transport system periplasmic component
FIU99_17565	COG1803	Methylglyoxal synthase
FIU99_17570	COG2188	Transcriptional regulator
FIU99_17580	COG1263	PTS System
FIU99_17580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FIU99_17585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU99_17590	COG0800	Aldolase
FIU99_17600	COG0546	phosphoglycolate phosphatase activity
FIU99_17615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU99_17620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIU99_17630	COG0583	DNA-binding transcription factor activity
FIU99_17635	COG3048	D-serine ammonia-lyase activity
FIU99_17645	COG0346	lactoylglutathione lyase activity
FIU99_17660	COG0456	acetyltransferase
FIU99_17660	COG1214	PFAM Peptidase M22, glycoprotease
FIU99_17690	COG0513	Belongs to the DEAD box helicase family
FIU99_17705	COG0814	amino acid
FIU99_17710	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU99_17710	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU99_17720	COG0513	Belongs to the DEAD box helicase family
FIU99_17735	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FIU99_17745	COG2897	thiosulfate sulfurtransferase activity
FIU99_17770	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FIU99_17775	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FIU99_17780	COG1522	sequence-specific DNA binding
FIU99_17790	COG0006	proline dipeptidase activity
FIU99_17795	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU99_17800	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIU99_17805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU99_17810	COG1473	amidohydrolase
FIU99_17820	COG1522	sequence-specific DNA binding
FIU99_17835	COG2199	diguanylate cyclase activity
FIU99_17855	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FIU99_17870	COG0523	cobalamin synthesis protein
FIU99_17875	COG0038	chloride channel
FIU99_17885	COG0156	8-amino-7-oxononanoate synthase activity
FIU99_17890	COG2205	protein histidine kinase activity
FIU99_17890	COG0784	Response regulator, receiver
FIU99_17895	COG0419	ATPase involved in DNA repair
FIU99_17905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FIU99_17910	COG3118	belongs to the thioredoxin family
FIU99_17935	COG2146	nitrite reductase [NAD(P)H] activity
FIU99_17940	COG2146	nitrite reductase [NAD(P)H] activity
FIU99_17940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIU99_17945	COG1116	anion transmembrane transporter activity
FIU99_17950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIU99_17955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FIU99_17955	COG1116	anion transmembrane transporter activity
FIU99_17965	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FIU99_17970	COG1648	precorrin-2 dehydrogenase activity
FIU99_17970	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FIU99_17975	COG0243	molybdopterin cofactor binding
FIU99_18015	COG2315	Protein conserved in bacteria
FIU99_18025	COG2199	diguanylate cyclase activity
FIU99_18025	COG2203	Gaf domain
FIU99_18050	COG3706	GGDEF domain
FIU99_18070	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FIU99_18075	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_18085	COG1024	Enoyl-CoA hydratase
FIU99_18090	COG1024	Enoyl-CoA hydratase
FIU99_18095	COG1960	acyl-CoA dehydrogenase activity
FIU99_18105	COG0183	Belongs to the thiolase family
FIU99_18115	COG1960	acyl-CoA dehydrogenase activity
FIU99_18120	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIU99_18155	COG2259	Doxx family
FIU99_18160	COG1741	Belongs to the pirin family
FIU99_18175	COG1115	amino acid carrier protein
FIU99_18180	COG0583	DNA-binding transcription factor activity
FIU99_18185	COG2910	NAD(P)H-binding
FIU99_18205	COG1716	ATPase activity
FIU99_18205	COG5001	Diguanylate cyclase
FIU99_18225	COG1858	cytochrome C peroxidase
FIU99_18250	COG0583	DNA-binding transcription factor activity
FIU99_18255	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FIU99_18260	COG3300	MHYT domain
FIU99_18260	COG5001	Diguanylate cyclase
FIU99_18270	COG0789	Transcriptional regulator
FIU99_18280	COG2176	DNA-directed DNA polymerase activity
FIU99_18285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU99_18290	COG1846	Transcriptional regulator
FIU99_18295	COG3706	GGDEF domain
FIU99_18315	COG2814	Major facilitator Superfamily
FIU99_18320	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FIU99_18325	COG0714	Associated with various cellular activities
FIU99_18330	COG0494	nUDIX hydrolase
FIU99_18340	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_18355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIU99_18360	COG0784	Response regulator, receiver
FIU99_18360	COG0835	chemotaxis
FIU99_18365	COG3706	GGDEF domain
FIU99_18390	COG1760	l-serine dehydratase
FIU99_18395	COG0583	DNA-binding transcription factor activity
FIU99_18400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU99_18405	COG2866	Carboxypeptidase
FIU99_18435	COG3842	ATPase activity
FIU99_18445	COG1840	ABC-type Fe3 transport system, periplasmic component
FIU99_18450	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FIU99_18475	COG2378	regulation of single-species biofilm formation
FIU99_18480	COG1011	Hydrolase
FIU99_18495	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FIU99_18500	COG1454	alcohol dehydrogenase
FIU99_18545	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIU99_18550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIU99_18600	COG3186	Phenylalanine-4-hydroxylase
FIU99_18605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIU99_18610	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIU99_18630	COG0784	Response regulator, receiver
FIU99_18630	COG2205	protein histidine kinase activity
FIU99_18635	COG2205	protein histidine kinase activity
FIU99_18635	COG0784	Response regulator, receiver
FIU99_18640	COG0612	Peptidase, M16
FIU99_18650	COG0798	PFAM Bile acid sodium symporter
FIU99_18680	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FIU99_18710	COG1063	alcohol dehydrogenase
FIU99_18715	COG0156	8-amino-7-oxononanoate synthase activity
FIU99_18720	COG2200	EAL domain
FIU99_18720	COG2202	Pas domain
FIU99_18720	COG2199	diguanylate cyclase activity
FIU99_18745	COG0346	lactoylglutathione lyase activity
FIU99_18755	COG4452	Inner membrane protein CreD
FIU99_18760	COG2205	protein histidine kinase activity
FIU99_18765	COG0745	RESPONSE REGULATOR receiver
FIU99_18780	COG0745	RESPONSE REGULATOR receiver
FIU99_18785	COG2205	protein histidine kinase activity
FIU99_18800	COG0667	Aldo Keto reductase
FIU99_18805	COG0583	DNA-binding transcription factor activity
FIU99_18820	COG0714	Associated with various cellular activities
FIU99_18835	COG2304	oxidoreductase activity
FIU99_18840	COG2304	oxidoreductase activity
FIU99_18865	COG0110	maltose O-acetyltransferase activity
FIU99_18870	COG1765	OsmC-like protein
FIU99_18875	COG0673	inositol 2-dehydrogenase activity
FIU99_18895	COG0531	amino acid
FIU99_18915	COG2205	protein histidine kinase activity
FIU99_18920	COG0745	RESPONSE REGULATOR receiver
FIU99_18945	COG1566	PFAM secretion protein HlyD family protein
FIU99_18955	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FIU99_18960	COG0402	S-adenosylhomocysteine deaminase activity
FIU99_18965	COG0861	Integral membrane protein TerC family
FIU99_18980	COG2205	protein histidine kinase activity
FIU99_18980	COG5002	protein histidine kinase activity
FIU99_18980	COG0784	Response regulator, receiver
FIU99_19020	COG4533	DNA binding
FIU99_19035	COG1943	Transposase
FIU99_19050	COG1175	transmembrane transport
FIU99_19060	COG3842	ATPase activity
FIU99_19065	COG2096	Adenosyltransferase
FIU99_19070	COG0748	coenzyme F420 binding
FIU99_19075	COG3721	Heme iron utilization protein
FIU99_19085	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FIU99_19090	COG0811	peptide transport
FIU99_19095	COG0848	biopolymer transport protein
FIU99_19105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU99_19110	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FIU99_19115	COG2814	Major facilitator Superfamily
FIU99_19125	COG0739	heme binding
FIU99_19140	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FIU99_19150	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FIU99_19160	COG0513	Belongs to the DEAD box helicase family
FIU99_19170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU99_19170	COG4191	Histidine kinase
FIU99_19175	COG3437	response regulator, receiver
FIU99_19175	COG0784	Response regulator, receiver
FIU99_19180	COG1609	Transcriptional regulator
FIU99_19185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU99_19190	COG1879	ABC-type sugar transport system periplasmic component
FIU99_19195	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIU99_19200	COG1129	ABC transporter
FIU99_19205	COG1869	D-ribose catabolic process
FIU99_19215	COG3469	chitinase activity
FIU99_19230	COG0004	ammonium transporteR
FIU99_19255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU99_19275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIU99_19280	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FIU99_19310	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FIU99_19315	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FIU99_19320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FIU99_19325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU99_19350	COG1609	Transcriptional regulator
FIU99_19355	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FIU99_19360	COG3265	gluconokinase activity
FIU99_19365	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU99_19375	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIU99_19400	COG0583	DNA-binding transcription factor activity
FIU99_19420	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FIU99_19430	COG0668	transmembrane transport
FIU99_19450	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FIU99_19490	COG3118	belongs to the thioredoxin family
FIU99_19495	COG4232	protein-disulfide reductase activity
FIU99_19510	COG1280	lysine exporter protein (LysE YggA)
FIU99_19545	COG0443	Heat shock 70 kDa protein
FIU99_19550	COG0583	DNA-binding transcription factor activity
FIU99_19560	COG4948	Mandelate Racemase Muconate Lactonizing
FIU99_19565	COG1396	sequence-specific DNA binding
FIU99_19570	COG5001	Diguanylate cyclase
FIU99_19580	COG3706	GGDEF domain
FIU99_19590	COG0642	Histidine kinase
FIU99_19595	COG0745	RESPONSE REGULATOR receiver
FIU99_19610	COG2130	NADP-dependent
FIU99_19625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FIU99_19655	COG0534	Mate efflux family protein
FIU99_19660	COG0444	Belongs to the ABC transporter superfamily
FIU99_19665	COG4608	Belongs to the ABC transporter superfamily
FIU99_19670	COG0747	negative chemotaxis
FIU99_19690	COG0366	Alpha amylase catalytic
FIU99_19720	COG3279	Response regulator of the LytR AlgR family
FIU99_19725	COG3275	phosphorelay sensor kinase activity
FIU99_19745	COG1136	(ABC) transporter
FIU99_19760	COG1012	belongs to the aldehyde dehydrogenase family
FIU99_19780	COG3530	Putative quorum-sensing-regulated virulence factor
FIU99_19795	COG1686	Belongs to the peptidase S11 family
FIU99_19810	COG3036	rescue of stalled ribosome
FIU99_19815	COG1278	Cold shock
FIU99_19830	COG1017	nitric oxide dioxygenase activity
FIU99_19830	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIU99_19835	COG3604	Transcriptional regulator
FIU99_19845	COG0546	phosphoglycolate phosphatase activity
FIU99_19850	COG2249	NAD(P)H dehydrogenase (quinone) activity
FIU99_19860	COG0534	Mate efflux family protein
FIU99_19870	COG0697	spore germination
FIU99_19885	COG2814	Major facilitator Superfamily
FIU99_19890	COG0583	DNA-binding transcription factor activity
FIU99_19895	COG5001	Diguanylate cyclase
FIU99_19945	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FIU99_19955	COG0297	glycogen (starch) synthase activity
FIU99_19955	COG0438	transferase activity, transferring glycosyl groups
FIU99_19965	COG1045	serine acetyltransferase
FIU99_19980	COG0438	transferase activity, transferring glycosyl groups
FIU99_19985	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FIU99_19990	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FIU99_19995	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FIU99_20000	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FIU99_20010	COG5001	Diguanylate cyclase
FIU99_20010	COG2203	Gaf domain
FIU99_20010	COG3706	GGDEF domain
FIU99_20010	COG4251	negative regulation of phosphorylation
FIU99_20015	COG4989	oxidoreductase activity
FIU99_20025	COG0366	Alpha amylase catalytic
FIU99_20035	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FIU99_20040	COG1126	abc transporter atp-binding protein
FIU99_20045	COG0765	amino acid transport
FIU99_20050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU99_20055	COG0765	amino acid transport
FIU99_20060	COG0109	protoheme IX farnesyltransferase activity
FIU99_20065	COG1612	heme a metabolic process
FIU99_20090	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FIU99_20095	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FIU99_20100	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FIU99_20105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIU99_20145	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIU99_20170	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU99_20185	COG1741	Belongs to the pirin family
FIU99_20195	COG2814	Major facilitator Superfamily
FIU99_20200	COG1686	Belongs to the peptidase S11 family
FIU99_20205	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FIU99_20210	COG0583	DNA-binding transcription factor activity
FIU99_20245	COG1253	flavin adenine dinucleotide binding
FIU99_20285	COG1280	lysine exporter protein (LysE YggA)
FIU99_20290	COG0583	DNA-binding transcription factor activity
FIU99_20345	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FIU99_20355	COG0523	cobalamin synthesis protein
FIU99_20360	COG2988	succinylglutamate desuccinylase activity
FIU99_20365	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FIU99_20405	COG1846	Transcriptional regulator
FIU99_20415	COG1280	lysine exporter protein (LysE YggA)
FIU99_20425	COG1177	transmembrane transport
FIU99_20430	COG1176	ABC-type spermidine putrescine transport system, permease component I
FIU99_20435	COG3842	ATPase activity
FIU99_20440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIU99_20445	COG2423	ornithine cyclodeaminase activity
FIU99_20460	COG3938	Belongs to the proline racemase family
FIU99_20470	COG2186	Transcriptional regulator
FIU99_20485	COG0601	transmembrane transport
FIU99_20490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU99_20505	COG0006	proline dipeptidase activity
FIU99_20540	COG3568	Endonuclease Exonuclease Phosphatase
FIU99_20545	COG3291	Pkd domain containing protein
FIU99_20550	COG0513	Belongs to the DEAD box helicase family
FIU99_20560	COG1376	ErfK ybiS ycfS ynhG family protein
FIU99_20560	COG1388	LysM domain
FIU99_20565	COG0415	Belongs to the DNA photolyase family
FIU99_20570	COG0789	Transcriptional regulator
FIU99_20575	COG3272	Protein of unknown function (DUF1722)
FIU99_20580	COG0813	purine-nucleoside phosphorylase activity
FIU99_20595	COG3706	GGDEF domain
FIU99_20610	COG1566	PFAM secretion protein HlyD family protein
FIU99_20615	COG0786	glutamate:sodium symporter activity
FIU99_20630	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIU99_20645	COG0583	DNA-binding transcription factor activity
FIU99_20655	COG1132	(ABC) transporter
FIU99_20700	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FIU99_20710	COG0259	pyridoxamine-phosphate oxidase activity
FIU99_20740	COG3033	Beta-eliminating lyase
FIU99_20745	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FIU99_20750	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FIU99_20755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FIU99_20765	COG1999	signal sequence binding
FIU99_20780	COG1671	Belongs to the UPF0178 family
FIU99_20785	COG0393	Putative heavy-metal-binding
FIU99_20790	COG0583	DNA-binding transcription factor activity
FIU99_20795	COG2814	Major facilitator Superfamily
FIU99_20830	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU99_20840	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU99_20850	COG0346	lactoylglutathione lyase activity
FIU99_20875	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FIU99_21035	COG1301	dicarboxylic acid transport
FIU99_21050	COG1404	Belongs to the peptidase S8 family
FIU99_21065	COG2207	Transcriptional regulator
FIU99_21075	COG0700	Nucleoside recognition
FIU99_21080	COG3366	ferrous iron transmembrane transporter activity
FIU99_21085	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FIU99_21100	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FIU99_21110	COG0745	RESPONSE REGULATOR receiver
FIU99_21115	COG5002	protein histidine kinase activity
FIU99_21130	COG4999	Histidine kinase
FIU99_21130	COG2205	protein histidine kinase activity
FIU99_21130	COG3437	response regulator, receiver
FIU99_21130	COG3850	Histidine kinase
FIU99_21135	COG0745	RESPONSE REGULATOR receiver
FIU99_21140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU99_21150	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FIU99_21175	COG0745	RESPONSE REGULATOR receiver
FIU99_21180	COG2205	protein histidine kinase activity
FIU99_21185	COG0471	metal ion transport
FIU99_21225	COG1595	DNA-templated transcription, initiation
FIU99_21240	COG0697	spore germination
FIU99_21245	COG0251	oxidation-reduction process
FIU99_21255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIU99_21255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIU99_21265	COG1063	alcohol dehydrogenase
FIU99_21305	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIU99_21315	COG1175	transmembrane transport
FIU99_21330	COG1940	carbohydrate kinase activity
FIU99_21340	COG0438	transferase activity, transferring glycosyl groups
FIU99_21350	COG0671	phosphoesterase, PA-phosphatase related
FIU99_21360	COG2207	Transcriptional regulator
FIU99_21360	COG3708	Transcriptional regulator
FIU99_21380	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FIU99_21385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FIU99_21390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIU99_21395	COG1116	anion transmembrane transporter activity
FIU99_21400	COG0351	phosphomethylpyrimidine kinase
FIU99_21405	COG0656	L-ascorbic acid biosynthetic process
FIU99_21425	COG0583	DNA-binding transcription factor activity
FIU99_21450	COG0840	transmembrane signaling receptor activity
FIU99_21455	COG0768	penicillin binding
FIU99_21460	COG2723	6-phospho-beta-galactosidase activity
FIU99_21470	COG3842	ATPase activity
FIU99_21475	COG0546	phosphoglycolate phosphatase activity
FIU99_21495	COG1175	transmembrane transport
FIU99_21500	COG0583	DNA-binding transcription factor activity
FIU99_21560	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FIU99_21580	COG0745	RESPONSE REGULATOR receiver
FIU99_21580	COG3706	GGDEF domain
FIU99_21605	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FIU99_21610	COG0840	transmembrane signaling receptor activity
FIU99_21615	COG0835	chemotaxis
FIU99_21630	COG0745	RESPONSE REGULATOR receiver
FIU99_21640	COG0840	transmembrane signaling receptor activity
FIU99_21645	COG1444	tRNA N-acetyltransferase activity
FIU99_21675	COG4608	Belongs to the ABC transporter superfamily
FIU99_21680	COG0444	Belongs to the ABC transporter superfamily
FIU99_21715	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_21725	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_21730	COG1733	regulation of RNA biosynthetic process
FIU99_21750	COG0583	DNA-binding transcription factor activity
FIU99_21755	COG1051	belongs to the nudix hydrolase family
FIU99_21770	COG3300	MHYT domain
FIU99_21770	COG5001	Diguanylate cyclase
FIU99_21775	COG0697	spore germination
FIU99_21780	COG1846	Transcriptional regulator
FIU99_21810	COG1288	antiporter activity
FIU99_21815	COG0583	DNA-binding transcription factor activity
FIU99_21825	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FIU99_21830	COG3960	tartronate-semialdehyde synthase activity
FIU99_21835	COG3622	Belongs to the hyi family
FIU99_21840	COG2084	Dehydrogenase
FIU99_21860	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FIU99_21875	COG0559	Belongs to the binding-protein-dependent transport system permease family
FIU99_21900	COG0831	urea catabolic process
FIU99_21905	COG0832	Belongs to the urease beta subunit family
FIU99_21910	COG0804	urea catabolic process
FIU99_21915	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FIU99_21960	COG0840	transmembrane signaling receptor activity
FIU99_21965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU99_21980	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FIU99_21990	COG4145	pantothenate transmembrane transporter activity
FIU99_21995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU99_22000	COG0800	Aldolase
FIU99_22010	COG2706	6-phosphogluconolactonase activity
FIU99_22020	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FIU99_22025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FIU99_22030	COG1845	cytochrome c oxidase, subunit III
FIU99_22035	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FIU99_22040	COG0109	protoheme IX farnesyltransferase activity
FIU99_22055	COG3179	chitinase
FIU99_22080	COG0583	DNA-binding transcription factor activity
FIU99_22105	COG3214	Protein conserved in bacteria
FIU99_22110	COG0596	Alpha beta hydrolase
FIU99_22125	COG2252	PERMEase
FIU99_22145	COG4266	Belongs to the allantoicase family
FIU99_22165	COG0840	transmembrane signaling receptor activity
FIU99_22175	COG1522	sequence-specific DNA binding
FIU99_22185	COG0784	Response regulator, receiver
FIU99_22185	COG2205	protein histidine kinase activity
FIU99_22185	COG5002	protein histidine kinase activity
FIU99_22190	COG2226	methyltransferase
FIU99_22195	COG0402	S-adenosylhomocysteine deaminase activity
FIU99_22205	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FIU99_22215	COG2186	Transcriptional regulator
FIU99_22240	COG3795	YCII-related domain
FIU99_22270	COG0402	S-adenosylhomocysteine deaminase activity
FIU99_22275	COG1404	Belongs to the peptidase S8 family
FIU99_22280	COG1335	isochorismatase
FIU99_22285	COG2207	Transcriptional regulator
FIU99_22330	COG2909	trisaccharide binding
FIU99_22335	COG0058	SHG alpha-glucan phosphorylase activity
FIU99_22340	COG1640	4-alpha-glucanotransferase
FIU99_22345	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FIU99_22360	COG1619	proteins homologs of microcin C7 resistance protein MccF
FIU99_22410	COG2249	NAD(P)H dehydrogenase (quinone) activity
FIU99_22420	COG0583	DNA-binding transcription factor activity
FIU99_22430	COG0300	oxidoreductase activity
FIU99_22480	COG0561	phosphatase activity
FIU99_22495	COG0024	Methionine aminopeptidase
FIU99_22520	COG1132	(ABC) transporter
FIU99_22525	COG1132	(ABC) transporter
FIU99_22530	COG1021	2,3-dihydroxybenzoate-AMP ligase
FIU99_22535	COG1169	isochorismate synthase
FIU99_22540	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FIU99_22555	COG2226	methyltransferase
FIU99_22555	COG3433	isochorismatase activity
FIU99_22555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FIU99_22560	COG2814	Major facilitator Superfamily
FIU99_22565	COG4771	TonB-dependent receptor
FIU99_22570	COG4977	sequence-specific DNA binding
FIU99_22570	COG1917	Cupin 2, conserved barrel domain protein
FIU99_22590	COG1733	regulation of RNA biosynthetic process
FIU99_22640	COG0702	epimerase
FIU99_22665	COG1414	Transcriptional regulator
FIU99_22670	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_22680	COG0583	DNA-binding transcription factor activity
FIU99_22705	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FIU99_22705	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU99_22705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU99_22710	COG0383	alpha-mannosidase activity
FIU99_22720	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU99_22720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU99_22720	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FIU99_22725	COG4968	Prepilin-type N-terminal cleavage methylation domain
FIU99_22735	COG2814	Major facilitator Superfamily
FIU99_22740	COG1120	ATPase activity
FIU99_22755	COG4264	IucA IucC family
FIU99_22780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU99_22790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FIU99_22800	COG0662	Cupin 2, conserved barrel domain protein
FIU99_22805	COG1960	acyl-CoA dehydrogenase activity
FIU99_22810	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FIU99_22815	COG2076	Multidrug Resistance protein
FIU99_22820	COG2076	Multidrug Resistance protein
FIU99_22825	COG0590	tRNA wobble adenosine to inosine editing
FIU99_22840	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FIU99_22840	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU99_22890	COG4175	Glycine betaine
FIU99_22890	COG3448	diguanylate cyclase activity
FIU99_22895	COG4176	ABC-type proline glycine betaine transport system permease component
FIU99_22915	COG2095	MarC family integral membrane protein
FIU99_22950	COG4964	Belongs to the GSP D family
FIU99_22960	COG2894	cell division
FIU99_23015	COG1477	protein flavinylation
FIU99_23035	COG4221	oxidoreductase activity
FIU99_23045	COG0840	transmembrane signaling receptor activity
FIU99_23050	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FIU99_23055	COG0573	inorganic phosphate transmembrane transporter activity
FIU99_23060	COG0581	inorganic phosphate transmembrane transporter activity
FIU99_23080	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FIU99_23085	COG1162	GTPase activity
FIU99_23105	COG1122	ATPase activity
FIU99_23110	COG4720	Psort location CytoplasmicMembrane, score
FIU99_23115	COG0363	glucosamine-6-phosphate deaminase activity
FIU99_23130	COG0454	-acetyltransferase
FIU99_23135	COG0840	transmembrane signaling receptor activity
FIU99_23165	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIU99_23170	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FIU99_23175	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FIU99_23185	COG1522	sequence-specific DNA binding
FIU99_23215	COG3608	succinylglutamate desuccinylase aspartoacylase
FIU99_23220	COG1288	antiporter activity
FIU99_23240	COG0745	RESPONSE REGULATOR receiver
FIU99_23285	COG0583	DNA-binding transcription factor activity
FIU99_23290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIU99_23295	COG1151	hydroxylamine reductase activity
FIU99_23305	COG0583	DNA-binding transcription factor activity
FIU99_23320	COG3604	Transcriptional regulator
FIU99_23345	COG0415	Belongs to the DNA photolyase family
FIU99_23350	COG3046	protein related to deoxyribodipyrimidine photolyase
FIU99_23360	COG2329	Antibiotic biosynthesis monooxygenase
FIU99_23365	COG3304	Inner membrane component domain
FIU99_23385	COG0583	DNA-binding transcription factor activity
FIU99_23390	COG1234	tRNA 3'-trailer cleavage
FIU99_23420	COG0004	ammonium transporteR
FIU99_23430	COG3383	formate dehydrogenase (NAD+) activity
FIU99_23435	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU99_23440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU99_23445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU99_23470	COG0739	heme binding
FIU99_23475	COG3047	cAMP biosynthetic process
FIU99_23500	COG0300	oxidoreductase activity
FIU99_23505	COG5553	Cysteine dioxygenase type I
FIU99_23510	COG0673	inositol 2-dehydrogenase activity
FIU99_23515	COG0488	(ABC) transporter
FIU99_23545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU99_23545	COG4191	Histidine kinase
FIU99_23550	COG1320	monovalent cation:proton antiporter activity
FIU99_23555	COG2212	antiporter activity
FIU99_23570	COG1006	Multisubunit Na H antiporter MnhC subunit
FIU99_23575	COG2111	Na H antiporter
FIU99_23575	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FIU99_23585	COG0589	response to stress
FIU99_23590	COG1132	(ABC) transporter
FIU99_23600	COG0583	DNA-binding transcription factor activity
FIU99_23625	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FIU99_23635	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIU99_23650	COG4580	involved in the transport of maltose and maltodextrins
FIU99_23660	COG0840	transmembrane signaling receptor activity
FIU99_23690	COG0840	transmembrane signaling receptor activity
FIU99_23720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIU99_23730	COG0415	Belongs to the DNA photolyase family
FIU99_23750	COG0697	spore germination
FIU99_23775	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FIU99_23775	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FIU99_23785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FIU99_23785	COG2207	Transcriptional regulator
FIU99_23790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU99_23810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU99_23820	COG1522	sequence-specific DNA binding
FIU99_23845	COG1357	PFAM Pentapeptide repeats (8 copies)
FIU99_23850	COG1294	oxidase, subunit
FIU99_23855	COG1271	oxidase subunit
FIU99_23860	COG1805	sodium ion transport
FIU99_23880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FIU99_23905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU99_23915	COG1309	transcriptional regulator
FIU99_23935	COG0745	RESPONSE REGULATOR receiver
FIU99_23940	COG5002	protein histidine kinase activity
FIU99_23975	COG0842	Transport permease protein
FIU99_23980	COG1131	(ABC) transporter
FIU99_24020	COG0346	lactoylglutathione lyase activity
FIU99_24025	COG0625	glutathione transferase activity
FIU99_24030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIU99_24040	COG0366	Alpha amylase catalytic
FIU99_24060	COG2084	Dehydrogenase
FIU99_24075	COG2130	NADP-dependent
FIU99_24080	COG1309	transcriptional regulator
FIU99_24085	COG3706	GGDEF domain
FIU99_24105	COG0513	Belongs to the DEAD box helicase family
FIU99_24115	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FIU99_24155	COG0573	inorganic phosphate transmembrane transporter activity
FIU99_24165	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIU99_24185	COG0395	ABC-type sugar transport system, permease component
FIU99_24190	COG1554	hydrolase, family 65, central catalytic
FIU99_24195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FIU99_24210	COG1621	beta-fructofuranosidase activity
FIU99_24220	COG0110	maltose O-acetyltransferase activity
FIU99_24260	COG0251	oxidation-reduction process
FIU99_24290	COG0564	pseudouridine synthase activity
FIU99_24315	COG0583	DNA-binding transcription factor activity
FIU99_24320	COG2814	Major facilitator Superfamily
FIU99_24345	COG0840	transmembrane signaling receptor activity
FIU99_24350	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FIU99_24360	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FIU99_24370	COG0579	oxidoreductase
FIU99_24400	COG1012	belongs to the aldehyde dehydrogenase family
FIU99_24405	COG3284	Transcriptional regulator
FIU99_24430	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FIU99_24435	COG0363	glucosamine-6-phosphate deaminase activity
FIU99_24440	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FIU99_24445	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FIU99_24455	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FIU99_24465	COG2271	Major facilitator Superfamily
FIU99_24470	COG3851	Histidine kinase
FIU99_24475	COG2197	response regulator
FIU99_24500	COG3217	Mosc domain protein beta barrel domain protein
FIU99_24500	COG0633	Ferredoxin
FIU99_24500	COG3217	Mosc domain protein beta barrel domain protein
FIU99_24500	COG0633	Ferredoxin
FIU99_24510	COG1349	DNA-binding transcription factor activity
FIU99_24535	COG2354	Protein conserved in bacteria
FIU99_24545	COG0366	Alpha amylase catalytic
FIU99_24570	COG1943	Transposase
FIU99_24585	COG0840	transmembrane signaling receptor activity
FIU99_24590	COG1366	Belongs to the anti-sigma-factor antagonist family
FIU99_24600	COG2172	sigma factor antagonist activity
FIU99_24610	COG4999	Histidine kinase
FIU99_24610	COG3850	Histidine kinase
FIU99_24610	COG3437	response regulator, receiver
FIU99_24610	COG2205	protein histidine kinase activity
FIU99_24615	COG3437	response regulator, receiver
FIU99_24630	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FIU99_24630	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FIU99_24635	COG0516	GMP reductase activity
FIU99_24645	COG1346	cytolysis
FIU99_24650	COG1404	Belongs to the peptidase S8 family
FIU99_24665	COG1309	transcriptional regulator
FIU99_24690	COG4175	Glycine betaine
FIU99_24690	COG3448	diguanylate cyclase activity
FIU99_24710	COG1304	FMN binding
FIU99_24715	COG1620	l-lactate permease
FIU99_24720	COG0583	DNA-binding transcription factor activity
FIU99_24725	COG4172	Belongs to the ABC transporter superfamily
FIU99_24735	COG1067	ATP-dependent peptidase activity
FIU99_24740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FIU99_24745	COG0840	transmembrane signaling receptor activity
FIU99_24760	COG4166	transmembrane transport
FIU99_24765	COG4174	ABC transporter (Permease)
FIU99_24770	COG4239	(ABC) transporter, permease
FIU99_24775	COG4172	Belongs to the ABC transporter superfamily
FIU99_24785	COG3706	GGDEF domain
FIU99_24785	COG0745	RESPONSE REGULATOR receiver
FIU99_24825	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU99_24830	COG4605	iron ion homeostasis
FIU99_24835	COG4604	ABC transporter, ATP-binding protein
FIU99_24840	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FIU99_24855	COG0004	ammonium transporteR
FIU99_24865	COG4206	TonB-dependent receptor
FIU99_24885	COG2271	Major facilitator Superfamily
FIU99_24895	COG0840	transmembrane signaling receptor activity
FIU99_24900	COG2199	diguanylate cyclase activity
FIU99_24900	COG2203	Gaf domain
FIU99_24910	COG0739	heme binding
FIU99_24935	COG0735	belongs to the Fur family
FIU99_24945	COG1280	lysine exporter protein (LysE YggA)
FIU99_24955	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIU99_24965	COG1609	Transcriptional regulator
FIU99_25020	COG2026	Addiction module toxin, RelE StbE family
FIU99_25060	COG0583	DNA-binding transcription factor activity
FIU99_25065	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_25075	COG4974	Belongs to the 'phage' integrase family
FIU99_25085	COG4771	TonB-dependent receptor
FIU99_25235	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIU99_25240	COG0305	Participates in initiation and elongation during chromosome replication
FIU99_25345	COG2003	Belongs to the UPF0758 family
FIU99_25380	COG0745	RESPONSE REGULATOR receiver
FIU99_25380	COG3706	GGDEF domain
FIU99_25385	COG4251	negative regulation of phosphorylation
FIU99_25385	COG3706	GGDEF domain
FIU99_25385	COG2203	Gaf domain
FIU99_25385	COG5001	Diguanylate cyclase
FIU99_25395	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FIU99_25430	COG2267	carboxylic ester hydrolase activity
FIU99_25460	COG2169	Transcriptional regulator
FIU99_25465	COG1335	isochorismatase
FIU99_25475	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FIU99_25535	COG1917	Cupin 2, conserved barrel domain protein
FIU99_25535	COG2169	Transcriptional regulator
FIU99_25580	COG0459	protein refolding
FIU99_25585	COG0071	Belongs to the small heat shock protein (HSP20) family
FIU99_25615	COG4580	involved in the transport of maltose and maltodextrins
FIU99_25625	COG1609	Transcriptional regulator
FIU99_25645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU99_25650	COG0444	Belongs to the ABC transporter superfamily
FIU99_25655	COG4608	Belongs to the ABC transporter superfamily
FIU99_25665	COG1917	Cupin 2, conserved barrel domain protein
FIU99_25665	COG2207	Transcriptional regulator
FIU99_25690	COG0583	DNA-binding transcription factor activity
FIU99_25695	COG0625	glutathione transferase activity
FIU99_25710	COG1917	Cupin 2, conserved barrel domain protein
FIU99_25710	COG2207	Transcriptional regulator
FIU99_25715	COG1280	lysine exporter protein (LysE YggA)
FIU99_25745	COG0583	DNA-binding transcription factor activity
FIU99_25755	COG2274	protein secretion by the type I secretion system
FIU99_25765	COG2274	protein secretion by the type I secretion system
FIU99_25775	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_25795	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FIU99_25795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FIU99_25830	COG1051	belongs to the nudix hydrolase family
FIU99_25835	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FIU99_25865	COG0583	DNA-binding transcription factor activity
FIU99_25875	COG0251	oxidation-reduction process
FIU99_25880	COG1742	UPF0060 membrane protein
FIU99_25915	COG0494	nUDIX hydrolase
FIU99_25940	COG4774	siderophore transport
FIU99_26000	COG2084	Dehydrogenase
FIU99_26020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU99_26120	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_26125	COG0583	DNA-binding transcription factor activity
FIU99_26140	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
FIU99_26160	COG0702	epimerase
FIU99_26170	COG0604	alcohol dehydrogenase
FIU99_26185	COG3246	L-lysine catabolic process to acetate
FIU99_26195	COG0183	Belongs to the thiolase family
FIU99_26200	COG0113	porphobilinogen synthase activity
FIU99_26215	COG0671	phosphoesterase, PA-phosphatase related
FIU99_26320	COG2205	protein histidine kinase activity
FIU99_26325	COG0745	RESPONSE REGULATOR receiver
FIU99_26335	COG3527	Alpha-acetolactate decarboxylase
FIU99_26345	COG0583	DNA-binding transcription factor activity
FIU99_26350	COG1028	Short-chain dehydrogenase reductase Sdr
FIU99_26360	COG0745	RESPONSE REGULATOR receiver
FIU99_26370	COG5001	Diguanylate cyclase
FIU99_26370	COG4251	negative regulation of phosphorylation
FIU99_26370	COG3706	GGDEF domain
FIU99_26370	COG2203	Gaf domain
FIU99_26385	COG0840	transmembrane signaling receptor activity
FIU99_26405	COG0583	DNA-binding transcription factor activity
FIU99_26410	COG0583	DNA-binding transcription factor activity
FIU99_26415	COG0431	NADPH-dependent FMN reductase
FIU99_26430	COG2203	Gaf domain
FIU99_26430	COG3706	GGDEF domain
FIU99_26430	COG4251	negative regulation of phosphorylation
FIU99_26430	COG5001	Diguanylate cyclase
FIU99_26445	COG1879	ABC-type sugar transport system periplasmic component
FIU99_26455	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FIU99_26480	COG0702	epimerase
FIU99_26505	COG1360	Flagellar Motor Protein
FIU99_26520	COG1309	transcriptional regulator
FIU99_26575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU99_26575	COG4191	Histidine kinase
FIU99_26590	COG5001	Diguanylate cyclase
FIU99_26590	COG3300	MHYT domain
FIU99_26595	COG4191	Histidine kinase
FIU99_26605	COG0745	RESPONSE REGULATOR receiver
FIU99_26635	COG3033	Beta-eliminating lyase
FIU99_26650	COG2814	Major facilitator Superfamily
FIU99_26660	COG1192	Involved in chromosome partitioning
FIU99_26675	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU99_26745	COG4191	Histidine kinase
FIU99_26750	COG1181	Belongs to the D-alanine--D-alanine ligase family
FIU99_26770	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FIU99_26780	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIU99_26780	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIU99_26985	COG0629	single-stranded DNA binding
FIU99_27135	COG1959	2 iron, 2 sulfur cluster binding
FIU99_27320	COG0860	N-Acetylmuramoyl-L-alanine amidase
FIU99_27320	COG2247	cell wall binding repeat
FIU99_27360	COG3093	addiction module antidote protein HigA
FIU99_27365	COG3549	Plasmid maintenance system killer
FIU99_27400	COG5301	cellulose 1,4-beta-cellobiosidase activity