locus-tag	class	description
Vspart_00002	COG0592	DNA-directed DNA polymerase activity
Vspart_00004	COG0187	DNA topoisomerase II activity
Vspart_00005	COG0071	Belongs to the small heat shock protein (HSP20) family
Vspart_00009	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
Vspart_00011	COG3977	Valine--pyruvate aminotransferase
Vspart_00013	COG0439	Biotin carboxylase
Vspart_00020	COG0751	glycine-tRNA ligase activity
Vspart_00021	COG0752	glycyl-tRNA synthetase alpha subunit
Vspart_00022	COG2119	membrane
Vspart_00024	COG3501	Rhs element vgr protein
Vspart_00034	COG0425	Belongs to the sulfur carrier protein TusA family
Vspart_00037	COG0129	dihydroxy-acid dehydratase activity
Vspart_00038	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Vspart_00039	COG3978	acetolactate synthase activity
Vspart_00041	COG0606	chelatase, subunit chli
Vspart_00042	COG0204	Acyl-transferase
Vspart_00043	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Vspart_00044	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Vspart_00046	COG3084	Protein conserved in bacteria
Vspart_00047	COG4326	sporulation control protein
Vspart_00048	COG1272	protein, Hemolysin III
Vspart_00049	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Vspart_00050	COG0569	domain protein
Vspart_00051	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Vspart_00051	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Vspart_00054	COG0758	DNA mediated transformation
Vspart_00055	COG2922	Belongs to the Smg family
Vspart_00056	COG0551	DNA topoisomerase type I activity
Vspart_00057	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Vspart_00058	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Vspart_00060	COG0009	L-threonylcarbamoyladenylate synthase
Vspart_00064	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Vspart_00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Vspart_00071	COG0840	transmembrane signaling receptor activity
Vspart_00072	COG0583	DNA-binding transcription factor activity
Vspart_00073	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Vspart_00074	COG2960	long-chain fatty acid transporting porin activity
Vspart_00075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vspart_00076	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vspart_00084	COG0747	negative chemotaxis
Vspart_00086	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Vspart_00088	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Vspart_00089	COG1172	Belongs to the binding-protein-dependent transport system permease family
Vspart_00090	COG1172	Belongs to the binding-protein-dependent transport system permease family
Vspart_00091	COG1129	ABC transporter
Vspart_00092	COG1879	ABC-type sugar transport system periplasmic component
Vspart_00094	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Vspart_00095	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Vspart_00098	COG0210	DNA helicase
Vspart_00101	COG0405	Gamma-glutamyltransferase
Vspart_00102	COG1280	lysine exporter protein (LysE YggA)
Vspart_00103	COG2962	Rard protein
Vspart_00104	COG0514	ATP-dependent DNA helicase (RecQ)
Vspart_00108	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Vspart_00109	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Vspart_00110	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Vspart_00111	COG2723	6-phospho-beta-galactosidase activity
Vspart_00112	COG1447	Phosphotransferase system cellobiose-specific component IIA
Vspart_00113	COG1609	Transcriptional regulator
Vspart_00115	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Vspart_00119	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vspart_00122	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vspart_00124	COG1162	GTPase activity
Vspart_00128	COG2003	Belongs to the UPF0758 family
Vspart_00129	COG0328	RNA-DNA hybrid ribonuclease activity
Vspart_00131	COG0270	DNA (cytosine-5-)-methyltransferase activity
Vspart_00135	COG1561	YicC-like family, N-terminal region
Vspart_00136	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Vspart_00137	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Vspart_00138	COG1560	Kdo2-lipid A biosynthetic process
Vspart_00139	COG1560	Kdo2-lipid A biosynthetic process
Vspart_00140	COG1309	transcriptional regulator
Vspart_00141	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Vspart_00142	COG0840	transmembrane signaling receptor activity
Vspart_00143	COG2003	Belongs to the UPF0758 family
Vspart_00145	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Vspart_00148	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Vspart_00149	COG0859	PFAM glycosyl transferase family 9
Vspart_00150	COG0463	Glycosyl transferase, family 2
Vspart_00151	COG0859	PFAM glycosyl transferase family 9
Vspart_00152	COG3642	lipopolysaccharide core region biosynthetic process
Vspart_00154	COG1519	Transferase
Vspart_00158	COG0859	PFAM glycosyl transferase family 9
Vspart_00160	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Vspart_00161	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Vspart_00162	COG0662	Cupin 2, conserved barrel domain protein
Vspart_00162	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
Vspart_00163	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Vspart_00170	COG0438	transferase activity, transferring glycosyl groups
Vspart_00174	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Vspart_00177	COG3959	Transketolase, thiamine diphosphate binding domain
Vspart_00178	COG3958	Transketolase
Vspart_00179	COG3958	Transketolase
Vspart_00190	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Vspart_00192	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Vspart_00199	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Vspart_00201	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Vspart_00202	COG3959	Transketolase, thiamine diphosphate binding domain
Vspart_00203	COG3958	Transketolase
Vspart_00206	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Vspart_00207	COG1088	dTDP-glucose 4,6-dehydratase activity
Vspart_00208	COG1215	transferase activity, transferring glycosyl groups
Vspart_00213	COG3068	Protein conserved in bacteria
Vspart_00214	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Vspart_00215	COG1573	uracil-dna glycosylase
Vspart_00216	COG0776	regulation of translation
Vspart_00219	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Vspart_00220	COG0745	RESPONSE REGULATOR receiver
Vspart_00221	COG2205	protein histidine kinase activity
Vspart_00222	COG2814	Major facilitator Superfamily
Vspart_00223	COG1566	PFAM secretion protein HlyD family protein
Vspart_00226	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Vspart_00227	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Vspart_00229	COG0194	GDP metabolic process
Vspart_00230	COG1301	dicarboxylic acid transport
Vspart_00231	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Vspart_00232	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Vspart_00235	COG4232	protein-disulfide reductase activity
Vspart_00236	COG1027	Aspartate ammonia-lyase
Vspart_00237	COG5001	Diguanylate cyclase
Vspart_00237	COG5002	protein histidine kinase activity
Vspart_00237	COG3447	MASE1 domain protein
Vspart_00238	COG3030	protein affecting phage T7 exclusion by the F plasmid
Vspart_00239	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Vspart_00246	COG2205	protein histidine kinase activity
Vspart_00247	COG0745	RESPONSE REGULATOR receiver
Vspart_00249	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Vspart_00251	COG0205	6-phosphofructokinase activity
Vspart_00252	COG1494	fructose-1,6-bisphosphatase
Vspart_00254	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Vspart_00255	COG0527	aspartate kinase activity
Vspart_00255	COG0460	homoserine dehydrogenase
Vspart_00256	COG0626	cystathionine gamma-synthase activity
Vspart_00257	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
Vspart_00259	COG0281	malic enzyme
Vspart_00260	COG0254	rRNA binding
Vspart_00261	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Vspart_00262	COG1609	Transcriptional regulator
Vspart_00264	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Vspart_00265	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Vspart_00266	COG1575	Belongs to the MenA family. Type 1 subfamily
Vspart_00268	COG0534	Mate efflux family protein
Vspart_00274	COG0459	protein refolding
Vspart_00275	COG1119	ATPase activity
Vspart_00277	COG1509	lysine 2,3-aminomutase activity
Vspart_00278	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Vspart_00280	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
Vspart_00281	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Vspart_00282	COG1053	succinate dehydrogenase
Vspart_00283	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
Vspart_00284	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Vspart_00285	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
Vspart_00286	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Vspart_00287	COG1045	serine acetyltransferase
Vspart_00288	COG1695	Transcriptional regulator
Vspart_00289	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Vspart_00290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Vspart_00291	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Vspart_00292	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Vspart_00293	COG0137	argininosuccinate synthase activity
Vspart_00294	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Vspart_00294	COG0165	Argininosuccinate lyase
Vspart_00295	COG0678	peroxiredoxin activity
Vspart_00295	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Vspart_00297	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Vspart_00302	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Vspart_00305	COG0338	D12 class N6 adenine-specific DNA methyltransferase
Vspart_00306	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Vspart_00308	COG0180	Tryptophanyl-tRNA synthetase
Vspart_00309	COG0446	pyridine nucleotide-disulphide oxidoreductase
Vspart_00311	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Vspart_00315	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Vspart_00317	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Vspart_00318	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Vspart_00320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Vspart_00323	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_00324	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_00329	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Vspart_00333	COG3954	Phosphoribulokinase
Vspart_00335	COG0429	hydrolase of the alpha beta-hydrolase fold
Vspart_00337	COG0488	(ABC) transporter
Vspart_00338	COG2249	NAD(P)H dehydrogenase (quinone) activity
Vspart_00341	COG1047	Peptidyl-prolyl cis-trans
Vspart_00342	COG1446	asparaginase
Vspart_00343	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Vspart_00344	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
Vspart_00345	COG0557	exoribonuclease II activity
Vspart_00346	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Vspart_00347	COG0051	transcription antitermination factor activity, RNA binding
Vspart_00348	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Vspart_00351	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Vspart_00352	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Vspart_00353	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Vspart_00355	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Vspart_00357	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Vspart_00358	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Vspart_00359	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Vspart_00360	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Vspart_00361	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Vspart_00362	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Vspart_00363	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Vspart_00364	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Vspart_00366	COG1841	ribosomal large subunit assembly
Vspart_00368	COG0201	protein transport
Vspart_00369	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Vspart_00371	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Vspart_00372	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Vspart_00375	COG0203	ribosomal protein L17
Vspart_00377	COG0545	Peptidyl-prolyl cis-trans isomerase
Vspart_00379	COG2153	protein acetylation
Vspart_00381	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Vspart_00381	COG1648	precorrin-2 dehydrogenase activity
Vspart_00383	COG2895	sulfate adenylyltransferase (ATP) activity
Vspart_00384	COG3273	potassium ion transport
Vspart_00384	COG0471	metal ion transport
Vspart_00385	COG0529	Catalyzes the synthesis of activated sulfate
Vspart_00389	COG1136	(ABC) transporter
Vspart_00392	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vspart_00393	COG0729	surface antigen
Vspart_00394	COG2911	Protein conserved in bacteria
Vspart_00395	COG2105	PFAM AIG2 family protein
Vspart_00396	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Vspart_00398	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Vspart_00399	COG0163	prenyltransferase activity
Vspart_00401	COG4143	(ABC) transporter
Vspart_00402	COG1178	ABC-type Fe3 transport system permease component
Vspart_00403	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
Vspart_00404	COG3028	Belongs to the UPF0307 family
Vspart_00405	COG0312	modulator of DNA gyrase
Vspart_00410	COG2239	Acts as a magnesium transporter
Vspart_00411	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vspart_00412	COG1660	Displays ATPase and GTPase activities
Vspart_00413	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vspart_00414	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Vspart_00416	COG1137	ATPase activity
Vspart_00419	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Vspart_00420	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Vspart_00420	COG0517	IMP dehydrogenase activity
Vspart_00422	COG1127	ABC transporter
Vspart_00423	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Vspart_00424	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Vspart_00425	COG2854	intermembrane phospholipid transfer
Vspart_00427	COG5007	Belongs to the BolA IbaG family
Vspart_00428	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Vspart_00429	COG0204	Acyl-transferase
Vspart_00430	COG0251	oxidation-reduction process
Vspart_00431	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
Vspart_00434	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Vspart_00435	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Vspart_00437	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Vspart_00439	COG0564	pseudouridine synthase activity
Vspart_00440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Vspart_00441	COG4269	membrane
Vspart_00444	COG0525	valine-tRNA ligase activity
Vspart_00445	COG2927	DNA polymerase III (CHI subunit)
Vspart_00446	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Vspart_00447	COG0795	lipopolysaccharide-transporting ATPase activity
Vspart_00448	COG0795	lipopolysaccharide-transporting ATPase activity
Vspart_00468	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Vspart_00478	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Vspart_00479	COG0473	3-isopropylmalate dehydrogenase activity
Vspart_00480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Vspart_00483	COG0583	DNA-binding transcription factor activity
Vspart_00484	COG0028	Belongs to the TPP enzyme family
Vspart_00486	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Vspart_00487	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Vspart_00488	COG1012	belongs to the aldehyde dehydrogenase family
Vspart_00489	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Vspart_00491	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Vspart_00492	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Vspart_00493	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Vspart_00494	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Vspart_00496	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
Vspart_00498	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Vspart_00499	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Vspart_00504	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
Vspart_00506	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Vspart_00510	COG3086	response to oxidative stress
Vspart_00511	COG0481	GTPase activity
Vspart_00513	COG0571	ribonuclease III activity
Vspart_00514	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Vspart_00515	COG1381	Involved in DNA repair and RecF pathway recombination
Vspart_00516	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Vspart_00517	COG0736	holo-[acyl-carrier-protein] synthase activity
Vspart_00518	COG2205	protein histidine kinase activity
Vspart_00518	COG3437	response regulator, receiver
Vspart_00518	COG3850	Histidine kinase
Vspart_00518	COG4999	Histidine kinase
Vspart_00520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Vspart_00521	COG3956	TIGRFAM MazG family protein
Vspart_00522	COG0504	CTP synthase activity
Vspart_00523	COG0148	phosphopyruvate hydratase activity
Vspart_00524	COG0617	tRNA 3'-terminal CCA addition
Vspart_00525	COG4991	sh3 domain protein
Vspart_00526	COG0306	phosphate transporter
Vspart_00527	COG1392	Phosphate transport regulator
Vspart_00528	COG3025	triphosphatase activity
Vspart_00530	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Vspart_00531	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Vspart_00531	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Vspart_00532	COG1538	Outer membrane efflux protein
Vspart_00533	COG0494	nUDIX hydrolase
Vspart_00534	COG3151	Protein conserved in bacteria
Vspart_00536	COG3150	esterase
Vspart_00537	COG0187	DNA topoisomerase II activity
Vspart_00538	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Vspart_00541	COG3220	belongs to the UPF0276 family
Vspart_00544	COG1595	DNA-templated transcription, initiation
Vspart_00545	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
Vspart_00546	COG0237	dephospho-CoA kinase activity
Vspart_00548	COG1459	type II secretion system
Vspart_00549	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Vspart_00552	COG0157	Belongs to the NadC ModD family
Vspart_00554	COG0716	FMN binding
Vspart_00555	COG4974	Belongs to the 'phage' integrase family
Vspart_00556	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Vspart_00557	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Vspart_00558	COG2186	Transcriptional regulator
Vspart_00559	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Vspart_00560	COG0508	dehydrogenase complex catalyzes the overall conversion of
Vspart_00561	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Vspart_00564	COG0288	reversible hydration of carbon dioxide
Vspart_00565	COG1131	(ABC) transporter
Vspart_00566	COG0842	Transport permease protein
Vspart_00568	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Vspart_00569	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Vspart_00570	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Vspart_00571	COG0235	Class ii aldolase
Vspart_00573	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
Vspart_00574	COG1414	Transcriptional regulator
Vspart_00575	COG3623	hexulose-6-phosphate isomerase
Vspart_00576	COG1129	ABC transporter
Vspart_00577	COG1172	Belongs to the binding-protein-dependent transport system permease family
Vspart_00582	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Vspart_00583	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Vspart_00584	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Vspart_00586	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Vspart_00587	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Vspart_00588	COG1489	DNA binding
Vspart_00589	COG1643	Atp-dependent helicase
Vspart_00590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Vspart_00591	COG1049	propionate catabolic process, 2-methylcitrate cycle
Vspart_00592	COG3112	Uncharacterised protein family (UPF0231)
Vspart_00595	COG0004	ammonium transporteR
Vspart_00597	COG0628	permease
Vspart_00598	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Vspart_00599	COG0316	Belongs to the HesB IscA family
Vspart_00600	COG0739	heme binding
Vspart_00601	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Vspart_00602	COG2027	D-alanyl-D-alanine carboxypeptidase
Vspart_00604	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Vspart_00605	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Vspart_00606	COG1534	Rna-binding protein
Vspart_00607	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Vspart_00608	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Vspart_00609	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Vspart_00611	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Vspart_00615	COG0779	Required for maturation of 30S ribosomal subunits
Vspart_00616	COG0195	Participates in both transcription termination and antitermination
Vspart_00617	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Vspart_00619	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Vspart_00621	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Vspart_00622	COG1185	polyribonucleotide nucleotidyltransferase activity
Vspart_00624	COG0534	Mate efflux family protein
Vspart_00625	COG0826	peptidase U32
Vspart_00626	COG0826	peptidase U32
Vspart_00628	COG3154	lipid carrier protein
Vspart_00629	COG3153	acetyltransferase
Vspart_00631	COG0456	acetyltransferase
Vspart_00632	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Vspart_00634	COG0489	protein tyrosine kinase activity
Vspart_00639	COG1216	Glycosyl transferase, family 2
Vspart_00639	COG1442	glycosyl transferase family 8
Vspart_00640	COG0438	transferase activity, transferring glycosyl groups
Vspart_00641	COG1045	serine acetyltransferase
Vspart_00642	COG0438	transferase activity, transferring glycosyl groups
Vspart_00646	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Vspart_00647	COG0726	polysaccharide deacetylase
Vspart_00650	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Vspart_00651	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
Vspart_00655	COG0745	RESPONSE REGULATOR receiver
Vspart_00658	COG0513	Belongs to the DEAD box helicase family
Vspart_00661	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Vspart_00662	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Vspart_00663	COG2204	response regulator
Vspart_00665	COG0667	Aldo Keto reductase
Vspart_00666	COG3066	DNA modification
Vspart_00667	COG0494	nUDIX hydrolase
Vspart_00669	COG0730	response to heat
Vspart_00670	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Vspart_00671	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Vspart_00672	COG0583	DNA-binding transcription factor activity
Vspart_00673	COG0640	Transcriptional regulator
Vspart_00675	COG0728	peptidoglycan biosynthetic process
Vspart_00677	COG0196	riboflavin kinase activity
Vspart_00679	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Vspart_00680	COG1047	Peptidyl-prolyl cis-trans
Vspart_00681	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Vspart_00682	COG1966	Carbon starvation protein
Vspart_00684	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Vspart_00685	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Vspart_00687	COG3279	Response regulator of the LytR AlgR family
Vspart_00688	COG3275	phosphorelay sensor kinase activity
Vspart_00689	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Vspart_00690	COG1605	Chorismate mutase
Vspart_00690	COG0287	Prephenate dehydrogenase
Vspart_00692	COG0488	(ABC) transporter
Vspart_00693	COG0741	lytic transglycosylase activity
Vspart_00694	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
Vspart_00698	COG5001	Diguanylate cyclase
Vspart_00699	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Vspart_00700	COG0077	Prephenate dehydratase
Vspart_00700	COG1605	Chorismate mutase
Vspart_00701	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Vspart_00702	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Vspart_00703	COG0564	pseudouridine synthase activity
Vspart_00705	COG0542	response to heat
Vspart_00720	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Vspart_00722	COG2974	May be involved in recombination
Vspart_00723	COG0745	RESPONSE REGULATOR receiver
Vspart_00724	COG5002	protein histidine kinase activity
Vspart_00726	COG0248	Ppx GppA phosphatase
Vspart_00727	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Vspart_00729	COG0581	inorganic phosphate transmembrane transporter activity
Vspart_00730	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Vspart_00731	COG0704	Plays a role in the regulation of phosphate uptake
Vspart_00732	COG0450	alkyl hydroperoxide reductase
Vspart_00733	COG0583	DNA-binding transcription factor activity
Vspart_00734	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Vspart_00736	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Vspart_00736	COG0617	tRNA 3'-terminal CCA addition
Vspart_00736	COG0517	IMP dehydrogenase activity
Vspart_00738	COG0343	queuine tRNA-ribosyltransferase activity
Vspart_00740	COG1862	Preprotein translocase
Vspart_00741	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Vspart_00742	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Vspart_00743	COG0483	inositol monophosphate 1-phosphatase activity
Vspart_00744	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
Vspart_00745	COG1959	2 iron, 2 sulfur cluster binding
Vspart_00746	COG1104	cysteine desulfurase activity
Vspart_00747	COG0822	iron-sulfur transferase activity
Vspart_00748	COG0316	Belongs to the HesB IscA family
Vspart_00751	COG0633	Ferredoxin
Vspart_00752	COG2975	iron-sulfur cluster assembly
Vspart_00754	COG0105	UTP biosynthetic process
Vspart_00755	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Vspart_00756	COG1426	Protein conserved in bacteria
Vspart_00758	COG0124	histidyl-tRNA synthetase
Vspart_00759	COG2976	Protein conserved in bacteria
Vspart_00760	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Vspart_00761	COG1160	GTP binding
Vspart_00764	COG0516	GMP reductase activity
Vspart_00764	COG0517	IMP dehydrogenase activity
Vspart_00765	COG0519	Catalyzes the synthesis of GMP from XMP
Vspart_00765	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Vspart_00773	COG0667	Aldo Keto reductase
Vspart_00774	COG0583	DNA-binding transcription factor activity
Vspart_00776	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Vspart_00779	COG1349	DNA-binding transcription factor activity
Vspart_00781	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vspart_00782	COG0738	Major facilitator superfamily
Vspart_00785	COG0477	Major facilitator Superfamily
Vspart_00789	COG0583	DNA-binding transcription factor activity
Vspart_00790	COG0789	Transcriptional regulator
Vspart_00791	COG0454	-acetyltransferase
Vspart_00793	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vspart_00794	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vspart_00796	COG5002	protein histidine kinase activity
Vspart_00799	COG1115	amino acid carrier protein
Vspart_00802	COG3623	hexulose-6-phosphate isomerase
Vspart_00803	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
Vspart_00804	COG0561	phosphatase activity
Vspart_00811	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vspart_00813	COG2207	Transcriptional regulator
Vspart_00814	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vspart_00814	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vspart_00814	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vspart_00816	COG3550	peptidyl-serine autophosphorylation
Vspart_00822	COG4804	nuclease activity
Vspart_00846	COG2501	S4 domain
Vspart_00847	COG0840	transmembrane signaling receptor activity
Vspart_00849	COG3711	transcriptional antiterminator
Vspart_00850	COG1263	PTS System
Vspart_00850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vspart_00850	COG2190	(PTS) system
Vspart_00851	COG1063	alcohol dehydrogenase
Vspart_00852	COG1802	Transcriptional regulator
Vspart_00853	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Vspart_00854	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Vspart_00855	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Vspart_00857	COG2721	sulfolactate sulfo-lyase activity
Vspart_00866	COG0205	6-phosphofructokinase activity
Vspart_00867	COG1881	PFAM PEBP family protein
Vspart_00875	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Vspart_00877	COG2801	Transposase and inactivated derivatives
Vspart_00879	COG2801	Transposase and inactivated derivatives
Vspart_00884	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Vspart_00885	COG2867	negative regulation of translational initiation
Vspart_00886	COG2914	Belongs to the UPF0125 (RnfH) family
Vspart_00887	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Vspart_00889	COG0497	DNA recombination
Vspart_00891	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Vspart_00893	COG2358	TRAP transporter, solute receptor (TAXI family
Vspart_00894	COG0443	Heat shock 70 kDa protein
Vspart_00895	COG0484	heat shock protein binding
Vspart_00902	COG0583	DNA-binding transcription factor activity
Vspart_00905	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Vspart_00907	COG0686	Belongs to the AlaDH PNT family
Vspart_00909	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Vspart_00916	COG1720	tRNA m6t6A37 methyltransferase activity
Vspart_00917	COG1671	Belongs to the UPF0178 family
Vspart_00922	COG3098	single-species biofilm formation
Vspart_00923	COG0564	pseudouridine synthase activity
Vspart_00924	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Vspart_00925	COG0142	geranyltranstransferase activity
Vspart_00926	COG1722	exodeoxyribonuclease VII activity
Vspart_00927	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Vspart_00929	COG4989	oxidoreductase activity
Vspart_00930	COG0301	tRNA thio-modification
Vspart_00930	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Vspart_00932	COG0583	DNA-binding transcription factor activity
Vspart_00936	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Vspart_00937	COG1611	Belongs to the LOG family
Vspart_00940	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Vspart_00940	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Vspart_00942	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
Vspart_00943	COG1464	Belongs to the NlpA lipoprotein family
Vspart_00944	COG2011	ABC-type metal ion transport system permease component
Vspart_00945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Vspart_00946	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Vspart_00949	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Vspart_00950	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Vspart_00952	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Vspart_00957	COG1686	Belongs to the peptidase S11 family
Vspart_00958	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Vspart_00959	COG0772	Belongs to the SEDS family
Vspart_00960	COG0768	penicillin binding
Vspart_00961	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Vspart_00962	COG0799	negative regulation of ribosome biogenesis
Vspart_00963	COG1466	dna polymerase III delta subunit
Vspart_00964	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
Vspart_00965	COG0495	leucyl-tRNA aminoacylation
Vspart_00967	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Vspart_00968	COG4535	Mg2 and Co2 transporter CorC
Vspart_00969	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Vspart_00970	COG1702	phosphate starvation-inducible protein PhoH
Vspart_00972	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Vspart_00973	COG2190	(PTS) system
Vspart_00974	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Vspart_00975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vspart_00976	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Vspart_00977	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
Vspart_00978	COG3115	cell septum assembly
Vspart_00979	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Vspart_00980	COG0789	Transcriptional regulator
Vspart_00981	COG3118	belongs to the thioredoxin family
Vspart_00982	COG0300	oxidoreductase activity
Vspart_00983	COG1090	epimerase
Vspart_00990	COG3710	Transcriptional regulator
Vspart_00991	COG0326	Molecular chaperone. Has ATPase activity
Vspart_00992	COG0563	adenylate kinase activity
Vspart_00993	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Vspart_00995	COG0367	asparagine synthase
Vspart_00996	COG1940	carbohydrate kinase activity
Vspart_00996	COG1846	Transcriptional regulator
Vspart_00999	COG0101	tRNA pseudouridine synthase activity
Vspart_01000	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Vspart_01001	COG0285	dihydrofolate synthase activity
Vspart_01002	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
Vspart_01003	COG1286	toxin biosynthetic process
Vspart_01004	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Vspart_01005	COG2056	Na+-H+ antiporter family
Vspart_01006	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Vspart_01008	COG0346	lactoylglutathione lyase activity
Vspart_01009	COG2186	Transcriptional regulator
Vspart_01011	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Vspart_01012	COG4660	Part of a membrane complex involved in electron transport
Vspart_01014	COG4658	electron transport chain
Vspart_01015	COG4656	Part of a membrane complex involved in electron transport
Vspart_01016	COG2878	Part of a membrane complex involved in electron transport
Vspart_01017	COG4657	Part of a membrane complex involved in electron transport
Vspart_01018	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_01020	COG3527	Alpha-acetolactate decarboxylase
Vspart_01023	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
Vspart_01026	COG0673	inositol 2-dehydrogenase activity
Vspart_01028	COG0673	inositol 2-dehydrogenase activity
Vspart_01031	COG1940	carbohydrate kinase activity
Vspart_01039	COG0556	nucleotide-excision repair
Vspart_01041	COG2204	response regulator
Vspart_01042	COG2198	Histidine kinase
Vspart_01043	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Vspart_01045	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Vspart_01046	COG0521	Mo-molybdopterin cofactor biosynthetic process
Vspart_01047	COG0315	cyclic pyranopterin monophosphate synthase activity
Vspart_01048	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
Vspart_01049	COG0314	molybdopterin synthase activity
Vspart_01053	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Vspart_01053	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Vspart_01054	COG0489	protein tyrosine kinase activity
Vspart_01055	COG0572	uridine kinase
Vspart_01056	COG2982	Protein involved in outer membrane biogenesis
Vspart_01058	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Vspart_01061	COG1250	3-hydroxyacyl-CoA dehydrogenase
Vspart_01061	COG1024	Enoyl-CoA hydratase
Vspart_01062	COG0778	Nitroreductase
Vspart_01063	COG0583	DNA-binding transcription factor activity
Vspart_01064	COG0745	RESPONSE REGULATOR receiver
Vspart_01066	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Vspart_01071	COG2983	Belongs to the UPF0260 family
Vspart_01076	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_01079	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Vspart_01083	COG0402	S-adenosylhomocysteine deaminase activity
Vspart_01085	COG2986	histidine ammonia-lyase
Vspart_01086	COG1228	amidohydrolase
Vspart_01088	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Vspart_01089	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
Vspart_01090	COG2831	hemolysin activation secretion protein
Vspart_01091	COG3210	domain, Protein
Vspart_01091	COG3210	domain, Protein
Vspart_01100	COG2207	Transcriptional regulator
Vspart_01101	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_01103	COG0531	amino acid
Vspart_01106	COG4303	Ethanolamine ammonia lyase large subunit
Vspart_01114	COG4628	conserved protein (DUF2132)
Vspart_01115	COG2199	diguanylate cyclase activity
Vspart_01115	COG2203	Gaf domain
Vspart_01118	COG0251	oxidation-reduction process
Vspart_01119	COG0814	amino acid
Vspart_01123	COG0747	negative chemotaxis
Vspart_01125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Vspart_01126	COG0444	Belongs to the ABC transporter superfamily
Vspart_01127	COG4608	Belongs to the ABC transporter superfamily
Vspart_01134	COG2814	Major facilitator Superfamily
Vspart_01138	COG4166	transmembrane transport
Vspart_01139	COG0601	transmembrane transport
Vspart_01141	COG4172	Belongs to the ABC transporter superfamily
Vspart_01142	COG0436	Aminotransferase
Vspart_01143	COG1169	isochorismate synthase
Vspart_01144	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
Vspart_01145	COG0596	Alpha beta hydrolase
Vspart_01146	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Vspart_01151	COG2855	membrane
Vspart_01155	COG1335	isochorismatase
Vspart_01157	COG1522	sequence-specific DNA binding
Vspart_01158	COG1946	Acyl-CoA thioesterase
Vspart_01168	COG0515	serine threonine protein kinase
Vspart_01168	COG2815	serine threonine protein kinase
Vspart_01174	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Vspart_01176	COG2223	nitrite transmembrane transporter activity
Vspart_01177	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
Vspart_01179	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
Vspart_01180	COG2181	nitrate reductase activity
Vspart_01181	COG2197	response regulator
Vspart_01182	COG3850	Histidine kinase
Vspart_01184	COG5297	Belongs to the glycosyl hydrolase family 6
Vspart_01187	COG0784	Response regulator, receiver
Vspart_01187	COG5002	protein histidine kinase activity
Vspart_01187	COG2205	protein histidine kinase activity
Vspart_01189	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Vspart_01190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Vspart_01190	COG2207	Transcriptional regulator
Vspart_01191	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
Vspart_01201	COG5002	protein histidine kinase activity
Vspart_01202	COG4145	pantothenate transmembrane transporter activity
Vspart_01204	COG1349	DNA-binding transcription factor activity
Vspart_01205	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Vspart_01206	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Vspart_01207	COG1882	Formate acetyltransferase
Vspart_01208	COG1879	ABC-type sugar transport system periplasmic component
Vspart_01211	COG0840	transmembrane signaling receptor activity
Vspart_01213	COG2226	methyltransferase
Vspart_01214	COG0676	glucose-6-phosphate 1-epimerase activity
Vspart_01215	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Vspart_01216	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vspart_01218	COG3139	Protein of unknown function (DUF1315)
Vspart_01219	COG0252	asparaginase activity
Vspart_01221	COG0616	signal peptide processing
Vspart_01222	COG0788	formyltetrahydrofolate deformylase activity
Vspart_01224	COG1199	ATP-dependent helicase activity
Vspart_01225	COG1214	PFAM Peptidase M22, glycoprotease
Vspart_01228	COG0596	Alpha beta hydrolase
Vspart_01229	COG0318	PFAM AMP-dependent synthetase and ligase
Vspart_01230	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Vspart_01231	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Vspart_01232	COG2894	cell division
Vspart_01234	COG3100	YcgL domain-containing protein
Vspart_01235	COG2951	lytic endotransglycosylase activity
Vspart_01244	COG2373	Large extracellular alpha-helical protein
Vspart_01245	COG4953	penicillin-binding protein 1C
Vspart_01246	COG4628	conserved protein (DUF2132)
Vspart_01247	COG0662	Cupin 2, conserved barrel domain protein
Vspart_01255	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Vspart_01255	COG2169	Transcriptional regulator
Vspart_01258	COG1846	Transcriptional regulator
Vspart_01258	COG1940	carbohydrate kinase activity
Vspart_01259	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Vspart_01260	COG0363	glucosamine-6-phosphate deaminase activity
Vspart_01261	COG1263	PTS System
Vspart_01261	COG2190	(PTS) system
Vspart_01261	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vspart_01262	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Vspart_01263	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Vspart_01264	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Vspart_01265	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Vspart_01266	COG0740	serine-type endopeptidase activity
Vspart_01268	COG4191	Histidine kinase
Vspart_01272	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Vspart_01273	COG0776	regulation of translation
Vspart_01274	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Vspart_01275	COG1555	photosystem II stabilization
Vspart_01279	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Vspart_01280	COG0539	negative regulation of cytoplasmic translation
Vspart_01282	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
Vspart_01283	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
Vspart_01284	COG0284	orotidine-5'-phosphate decarboxylase activity
Vspart_01287	COG0583	DNA-binding transcription factor activity
Vspart_01288	COG1522	sequence-specific DNA binding
Vspart_01289	COG1674	ftsk spoiiie
Vspart_01290	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Vspart_01291	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Vspart_01292	COG2186	Transcriptional regulator
Vspart_01294	COG0537	adenosine 5'-monophosphoramidase activity
Vspart_01300	COG1252	NADH dehydrogenase
Vspart_01311	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Vspart_01313	COG4591	ABC-type transport system involved in lipoprotein release permease component
Vspart_01314	COG1136	(ABC) transporter
Vspart_01315	COG4591	ABC-type transport system involved in lipoprotein release permease component
Vspart_01317	COG2333	competence protein COMEC
Vspart_01317	COG0658	competence protein
Vspart_01318	COG1132	(ABC) transporter
Vspart_01319	COG1663	tetraacyldisaccharide 4'-kinase activity
Vspart_01321	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Vspart_01322	COG2719	SpoVR family
Vspart_01323	COG2718	Belongs to the UPF0229 family
Vspart_01324	COG2766	serine protein kinase
Vspart_01325	COG3013	Belongs to the UPF0304 family
Vspart_01326	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Vspart_01328	COG1882	Formate acetyltransferase
Vspart_01332	COG3923	Primosomal replication protein n
Vspart_01333	COG0730	response to heat
Vspart_01334	COG1199	ATP-dependent helicase activity
Vspart_01335	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Vspart_01338	COG3012	SEC-C Motif Domain Protein
Vspart_01339	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Vspart_01340	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Vspart_01341	COG0215	cysteine-tRNA ligase activity
Vspart_01342	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Vspart_01343	COG0632	four-way junction helicase activity
Vspart_01345	COG1271	oxidase subunit
Vspart_01346	COG1294	oxidase, subunit
Vspart_01347	COG4890	Cyd operon protein YbgT
Vspart_01348	COG3790	cyd operon protein YbgE
Vspart_01349	COG0824	Thioesterase
Vspart_01350	COG0811	peptide transport
Vspart_01354	COG2885	chlorophyll binding
Vspart_01355	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
Vspart_01356	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Vspart_01361	COG4221	oxidoreductase activity
Vspart_01361	COG3321	synthase
Vspart_01361	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_01361	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vspart_01383	COG2801	Transposase and inactivated derivatives
Vspart_01385	COG0604	alcohol dehydrogenase
Vspart_01386	COG1053	succinate dehydrogenase
Vspart_01386	COG3976	FMN-binding domain protein
Vspart_01386	COG0431	NADPH-dependent FMN reductase
Vspart_01388	COG2814	Major facilitator Superfamily
Vspart_01389	COG3290	protein histidine kinase activity
Vspart_01390	COG0471	metal ion transport
Vspart_01391	COG4565	transcriptional regulatory protein
Vspart_01392	COG2828	Protein conserved in bacteria
Vspart_01393	COG1049	propionate catabolic process, 2-methylcitrate cycle
Vspart_01394	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_01396	COG0346	lactoylglutathione lyase activity
Vspart_01403	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Vspart_01404	COG1629	transport
Vspart_01404	COG4774	siderophore transport
Vspart_01405	COG2382	esterase
Vspart_01408	COG1120	ATPase activity
Vspart_01409	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vspart_01410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vspart_01412	COG4592	Periplasmic binding protein
Vspart_01413	COG1535	isochorismatase
Vspart_01413	COG3433	isochorismatase activity
Vspart_01414	COG1021	2,3-dihydroxybenzoate-AMP ligase
Vspart_01415	COG1169	isochorismate synthase
Vspart_01416	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_01421	COG0765	amino acid transport
Vspart_01422	COG0765	amino acid transport
Vspart_01423	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vspart_01425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vspart_01428	COG3591	Belongs to the peptidase S1B family
Vspart_01430	COG2423	ornithine cyclodeaminase activity
Vspart_01432	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Vspart_01436	COG3501	Rhs element vgr protein
Vspart_01446	COG3501	Rhs element vgr protein
Vspart_01457	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Vspart_01458	COG3842	ATPase activity
Vspart_01461	COG1840	ABC-type Fe3 transport system, periplasmic component
Vspart_01462	COG1609	Transcriptional regulator
Vspart_01464	COG0739	heme binding
Vspart_01469	COG1342	Belongs to the UPF0251 family
Vspart_01471	COG1132	(ABC) transporter
Vspart_01472	COG1132	(ABC) transporter
Vspart_01473	COG1477	protein flavinylation
Vspart_01474	COG0569	domain protein
Vspart_01475	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Vspart_01477	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Vspart_01478	COG2985	domain, Protein
Vspart_01478	COG3273	potassium ion transport
Vspart_01479	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Vspart_01480	COG1737	Transcriptional regulator
Vspart_01481	COG0076	glutamate decarboxylase activity
Vspart_01483	COG3070	regulator of competence-specific genes
Vspart_01486	COG4191	Histidine kinase
Vspart_01488	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Vspart_01489	COG1032	radical SAM domain protein
Vspart_01492	COG1522	sequence-specific DNA binding
Vspart_01494	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vspart_01495	COG0765	amino acid transport
Vspart_01496	COG1126	abc transporter atp-binding protein
Vspart_01499	COG2350	Protein conserved in bacteria
Vspart_01500	COG1607	acyl-coa hydrolase
Vspart_01504	COG1301	dicarboxylic acid transport
Vspart_01505	COG0159	tryptophan synthase activity
Vspart_01506	COG0133	tryptophan synthase activity
Vspart_01507	COG0134	indole-3-glycerol-phosphate synthase activity
Vspart_01507	COG0135	phosphoribosylanthranilate isomerase activity
Vspart_01508	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Vspart_01509	COG0512	Glutamine amidotransferase of anthranilate synthase
Vspart_01510	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Vspart_01512	COG0009	L-threonylcarbamoyladenylate synthase
Vspart_01513	COG1187	pseudouridine synthase activity
Vspart_01514	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Vspart_01515	COG4988	ABC transporter
Vspart_01516	COG0492	ferredoxin-NADP+ reductase activity
Vspart_01518	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Vspart_01520	COG2949	membrane
Vspart_01522	COG0281	malic enzyme
Vspart_01524	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Vspart_01530	COG0277	FAD linked oxidase domain protein
Vspart_01530	COG0247	lactate metabolic process
Vspart_01533	COG3099	Belongs to the UPF0263 family
Vspart_01536	COG0417	DNA replication proofreading
Vspart_01538	COG2197	response regulator
Vspart_01539	COG0322	excinuclease ABC activity
Vspart_01541	COG0390	transport system, permease component
Vspart_01543	COG4172	Belongs to the ABC transporter superfamily
Vspart_01546	COG4168	peptide transport system, permease
Vspart_01548	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Vspart_01549	COG1842	Phage shock protein A
Vspart_01551	COG1983	PspC domain protein
Vspart_01552	COG0626	cystathionine gamma-synthase activity
Vspart_01554	COG0840	transmembrane signaling receptor activity
Vspart_01555	COG0733	neurotransmitter:sodium symporter activity
Vspart_01556	COG0564	pseudouridine synthase activity
Vspart_01557	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Vspart_01557	COG0116	Belongs to the methyltransferase superfamily
Vspart_01559	COG3313	Fe-S protein
Vspart_01562	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Vspart_01563	COG1061	Type III restriction enzyme res subunit
Vspart_01564	COG1187	pseudouridine synthase activity
Vspart_01565	COG2814	Major facilitator Superfamily
Vspart_01567	COG2249	NAD(P)H dehydrogenase (quinone) activity
Vspart_01568	COG0583	DNA-binding transcription factor activity
Vspart_01584	COG2169	Transcriptional regulator
Vspart_01584	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Vspart_01585	COG2176	DNA-directed DNA polymerase activity
Vspart_01591	COG1280	lysine exporter protein (LysE YggA)
Vspart_01594	COG2801	Transposase and inactivated derivatives
Vspart_01595	COG0702	epimerase
Vspart_01597	COG4181	ATPase activity
Vspart_01610	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Vspart_01611	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Vspart_01613	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Vspart_01614	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Vspart_01617	COG1846	Transcriptional regulator
Vspart_01618	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Vspart_01624	COG3290	protein histidine kinase activity
Vspart_01625	COG4565	transcriptional regulatory protein
Vspart_01630	COG1335	isochorismatase
Vspart_01631	COG4565	transcriptional regulatory protein
Vspart_01634	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
Vspart_01636	COG2301	Belongs to the HpcH HpaI aldolase family
Vspart_01640	COG0840	transmembrane signaling receptor activity
Vspart_01641	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Vspart_01642	COG1254	Belongs to the acylphosphatase family
Vspart_01643	COG2920	part of a sulfur-relay system
Vspart_01644	COG0670	Belongs to the BI1 family
Vspart_01646	COG1126	abc transporter atp-binding protein
Vspart_01647	COG0765	amino acid transport
Vspart_01648	COG4597	amino acid ABC transporter
Vspart_01649	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vspart_01652	COG1666	GTP binding
Vspart_01653	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Vspart_01656	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Vspart_01656	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
Vspart_01657	COG1956	GAF domain-containing protein
Vspart_01658	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
Vspart_01659	COG0793	Belongs to the peptidase S41A family
Vspart_01661	COG0308	aminopeptidase N
Vspart_01662	COG2902	Dehydrogenase
Vspart_01665	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Vspart_01665	COG0116	Belongs to the methyltransferase superfamily
Vspart_01669	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Vspart_01670	COG1067	ATP-dependent peptidase activity
Vspart_01671	COG3120	sequence-specific DNA binding
Vspart_01679	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
Vspart_01680	COG0574	Belongs to the PEP-utilizing enzyme family
Vspart_01680	COG3848	Pyruvate phosphate dikinase
Vspart_01681	COG0028	Belongs to the TPP enzyme family
Vspart_01683	COG1414	Transcriptional regulator
Vspart_01683	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Vspart_01684	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Vspart_01685	COG0156	8-amino-7-oxononanoate synthase activity
Vspart_01686	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vspart_01687	COG3321	synthase
Vspart_01688	COG3321	synthase
Vspart_01691	COG0778	Nitroreductase
Vspart_01693	COG0784	Response regulator, receiver
Vspart_01693	COG2205	protein histidine kinase activity
Vspart_01696	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Vspart_01697	COG0589	response to stress
Vspart_01698	COG0037	tRNA processing
Vspart_01701	COG3842	ATPase activity
Vspart_01702	COG1176	ABC-type spermidine putrescine transport system, permease component I
Vspart_01703	COG1177	transmembrane transport
Vspart_01705	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Vspart_01706	COG0814	amino acid
Vspart_01707	COG0004	ammonium transporteR
Vspart_01709	COG3829	transcription factor binding
Vspart_01710	COG0746	molybdenum cofactor guanylyltransferase activity
Vspart_01711	COG1763	Mo-molybdopterin cofactor biosynthetic process
Vspart_01712	COG1940	carbohydrate kinase activity
Vspart_01713	COG0840	transmembrane signaling receptor activity
Vspart_01715	COG3001	Fructosamine kinase
Vspart_01716	COG0307	riboflavin synthase, alpha
Vspart_01717	COG0534	Mate efflux family protein
Vspart_01718	COG1793	dna ligase
Vspart_01721	COG0848	biopolymer transport protein
Vspart_01722	COG0811	peptide transport
Vspart_01723	COG0811	peptide transport
Vspart_01725	COG0584	glycerophosphoryl diester phosphodiesterase
Vspart_01729	COG1115	amino acid carrier protein
Vspart_01733	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
Vspart_01735	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Vspart_01736	COG2207	Transcriptional regulator
Vspart_01736	COG1609	Transcriptional regulator
Vspart_01762	COG2801	Transposase and inactivated derivatives
Vspart_01763	COG4735	regulation of single-species biofilm formation
Vspart_01768	COG3842	ATPase activity
Vspart_01774	COG0640	Transcriptional regulator
Vspart_01775	COG0431	NADPH-dependent FMN reductase
Vspart_01776	COG0798	PFAM Bile acid sodium symporter
Vspart_01780	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Vspart_01781	COG1085	galactose-1-phosphate uridylyltransferase
Vspart_01782	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Vspart_01783	COG0840	transmembrane signaling receptor activity
Vspart_01784	COG4580	involved in the transport of maltose and maltodextrins
Vspart_01785	COG1874	Beta-galactosidase
Vspart_01787	COG3833	ABC-type maltose transport systems, permease component
Vspart_01788	COG1175	transmembrane transport
Vspart_01789	COG2182	Extracellular solute-binding protein
Vspart_01791	COG1609	Transcriptional regulator
Vspart_01794	COG0583	DNA-binding transcription factor activity
Vspart_01795	COG1053	succinate dehydrogenase
Vspart_01795	COG0431	NADPH-dependent FMN reductase
Vspart_01795	COG3976	FMN-binding domain protein
Vspart_01798	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Vspart_01800	COG1643	Atp-dependent helicase
Vspart_01803	COG1309	transcriptional regulator
Vspart_01808	COG0443	Heat shock 70 kDa protein
Vspart_01809	COG0443	Heat shock 70 kDa protein
Vspart_01812	COG0602	queuosine metabolic process
Vspart_01813	COG0561	phosphatase activity
Vspart_01814	COG0456	acetyltransferase
Vspart_01816	COG2079	MmgE PrpD family protein
Vspart_01817	COG0372	Belongs to the citrate synthase family
Vspart_01818	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Vspart_01820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vspart_01822	COG3768	UPF0283 membrane protein
Vspart_01823	COG3106	COG3106 Predicted ATPase
Vspart_01831	COG0494	nUDIX hydrolase
Vspart_01833	COG1760	l-serine dehydratase
Vspart_01834	COG0720	synthase
Vspart_01835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Vspart_01835	COG1017	nitric oxide dioxygenase activity
Vspart_01837	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vspart_01837	COG2190	(PTS) system
Vspart_01837	COG1263	PTS System
Vspart_01840	COG0646	methionine synthase
Vspart_01840	COG1410	methionine synthase
Vspart_01843	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vspart_01844	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vspart_01845	COG1120	ATPase activity
Vspart_01846	COG0583	DNA-binding transcription factor activity
Vspart_01847	COG4774	siderophore transport
Vspart_01848	COG0840	transmembrane signaling receptor activity
Vspart_01851	COG3706	GGDEF domain
Vspart_01852	COG2249	NAD(P)H dehydrogenase (quinone) activity
Vspart_01862	COG3209	COG3209 Rhs family protein
Vspart_01865	COG3209	COG3209 Rhs family protein
Vspart_01870	COG2801	Transposase and inactivated derivatives
Vspart_01874	COG3209	COG3209 Rhs family protein
Vspart_01877	COG3209	COG3209 Rhs family protein
Vspart_01882	COG3209	COG3209 Rhs family protein
Vspart_01886	COG3209	COG3209 Rhs family protein
Vspart_01889	COG3196	Protein conserved in bacteria
Vspart_01890	COG3209	COG3209 Rhs family protein
Vspart_01890	COG3209	COG3209 Rhs family protein
Vspart_01892	COG3501	Rhs element vgr protein
Vspart_01894	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Vspart_01896	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Vspart_01897	COG2181	nitrate reductase activity
Vspart_01897	COG0247	lactate metabolic process
Vspart_01898	COG0446	pyridine nucleotide-disulphide oxidoreductase
Vspart_01898	COG1902	pentaerythritol trinitrate reductase activity
Vspart_01902	COG1760	l-serine dehydratase
Vspart_01908	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Vspart_01909	COG0017	Asparaginyl-tRNA synthetase
Vspart_01910	COG1448	Aminotransferase
Vspart_01913	COG0402	S-adenosylhomocysteine deaminase activity
Vspart_01916	COG3008	intermembrane lipid transfer
Vspart_01916	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Vspart_01917	COG2995	paraquat-inducible protein a
Vspart_01920	COG0837	glucose binding
Vspart_01927	COG3842	ATPase activity
Vspart_01929	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Vspart_01937	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Vspart_01949	COG2801	Transposase and inactivated derivatives
Vspart_01959	COG3833	ABC-type maltose transport systems, permease component
Vspart_01960	COG1175	transmembrane transport
Vspart_01962	COG3842	ATPase activity
Vspart_01963	COG1640	4-alpha-glucanotransferase
Vspart_01964	COG0058	SHG alpha-glucan phosphorylase activity
Vspart_01965	COG2909	trisaccharide binding
Vspart_01970	COG2199	diguanylate cyclase activity
Vspart_01972	COG0835	chemotaxis
Vspart_01972	COG0784	Response regulator, receiver
Vspart_01978	COG0583	DNA-binding transcription factor activity
Vspart_01982	COG1538	Outer membrane efflux protein
Vspart_01985	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
Vspart_01986	COG4139	cobalamin transport
Vspart_01987	COG2988	succinylglutamate desuccinylase activity
Vspart_01988	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Vspart_02016	COG2925	Exonuclease
Vspart_02017	COG1380	Effector of murein hydrolase LrgA
Vspart_02018	COG1346	cytolysis
Vspart_02019	COG0295	cytidine deaminase activity
Vspart_02021	COG0500	methyltransferase
Vspart_02022	COG0776	regulation of translation
Vspart_02023	COG0072	phenylalanine-tRNA ligase activity
Vspart_02023	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Vspart_02024	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Vspart_02026	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vspart_02033	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Vspart_02034	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Vspart_02038	COG1435	thymidine kinase activity
Vspart_02039	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Vspart_02040	COG1801	Protein of unknown function DUF72
Vspart_02041	COG4106	trans-aconitate 2-methyltransferase activity
Vspart_02042	COG0500	methyltransferase
Vspart_02043	COG4067	protein conserved in archaea
Vspart_02043	COG0189	ligase activity
Vspart_02045	COG0189	ligase activity
Vspart_02046	COG0463	Glycosyl transferase, family 2
Vspart_02050	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
Vspart_02052	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Vspart_02053	COG1434	Gram-negative-bacterium-type cell wall biogenesis
Vspart_02054	COG1609	Transcriptional regulator
Vspart_02056	COG3070	regulator of competence-specific genes
Vspart_02059	COG0297	glycogen (starch) synthase activity
Vspart_02060	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Vspart_02061	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Vspart_02063	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Vspart_02066	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
Vspart_02067	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Vspart_02068	COG0542	response to heat
Vspart_02069	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Vspart_02070	COG1278	Cold shock
Vspart_02072	COG1187	pseudouridine synthase activity
Vspart_02073	COG0140	phosphoribosyl-ATP diphosphatase activity
Vspart_02073	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Vspart_02075	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Vspart_02076	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Vspart_02077	COG0131	Imidazoleglycerol-phosphate dehydratase
Vspart_02077	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Vspart_02078	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Vspart_02079	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Vspart_02080	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Vspart_02082	COG1757	Na H antiporter
Vspart_02084	COG2916	Histone family protein nucleoid-structuring protein H-NS
Vspart_02085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vspart_02086	COG0482	sulfurtransferase activity
Vspart_02088	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Vspart_02091	COG0754	glutathionylspermidine amidase activity
Vspart_02093	COG1842	Phage shock protein A
Vspart_02094	COG0137	argininosuccinate synthase activity
Vspart_02096	COG3766	membrane
Vspart_02098	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Vspart_02099	COG2226	methyltransferase
Vspart_02100	COG0156	8-amino-7-oxononanoate synthase activity
Vspart_02101	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Vspart_02111	COG0488	(ABC) transporter
Vspart_02116	COG2205	protein histidine kinase activity
Vspart_02118	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Vspart_02120	COG0653	protein targeting
Vspart_02125	COG4120	Belongs to the binding-protein-dependent transport system permease family
Vspart_02127	COG3092	negative regulation of chromosome organization
Vspart_02128	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Vspart_02129	COG0280	phosphate acetyltransferase
Vspart_02129	COG0857	belongs to the CobB CobQ family
Vspart_02130	COG0435	Glutathione S-transferase
Vspart_02131	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vspart_02132	COG1621	beta-fructofuranosidase activity
Vspart_02134	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vspart_02134	COG1263	PTS System
Vspart_02136	COG0745	RESPONSE REGULATOR receiver
Vspart_02138	COG4139	cobalamin transport
Vspart_02140	COG2204	response regulator
Vspart_02142	COG3852	Histidine kinase
Vspart_02144	COG3437	response regulator, receiver
Vspart_02147	COG0702	epimerase
Vspart_02148	COG1733	regulation of RNA biosynthetic process
Vspart_02150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vspart_02151	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vspart_02152	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Vspart_02153	COG4948	Mandelate Racemase Muconate Lactonizing
Vspart_02155	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Vspart_02156	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Vspart_02157	COG1984	allophanate hydrolase subunit 2
Vspart_02158	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Vspart_02159	COG4943	cyclic-guanylate-specific phosphodiesterase activity
Vspart_02160	COG2084	Dehydrogenase
Vspart_02161	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Vspart_02162	COG3507	Belongs to the glycosyl hydrolase 43 family
Vspart_02184	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Vspart_02185	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Vspart_02185	COG0574	Belongs to the PEP-utilizing enzyme family
Vspart_02186	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Vspart_02190	COG1053	succinate dehydrogenase
Vspart_02191	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Vspart_02192	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
Vspart_02194	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Vspart_02195	COG3290	protein histidine kinase activity
Vspart_02196	COG4565	transcriptional regulatory protein
Vspart_02198	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Vspart_02199	COG1349	DNA-binding transcription factor activity
Vspart_02201	COG2271	Major facilitator Superfamily
Vspart_02204	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Vspart_02205	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
Vspart_02206	COG0789	Transcriptional regulator
Vspart_02208	COG0616	signal peptide processing
Vspart_02209	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_02210	COG0784	Response regulator, receiver
Vspart_02210	COG0835	chemotaxis
Vspart_02211	COG1940	carbohydrate kinase activity
Vspart_02212	COG0469	pyruvate kinase activity
Vspart_02213	COG4667	esterase of the alpha-beta hydrolase superfamily
Vspart_02215	COG0733	neurotransmitter:sodium symporter activity
Vspart_02218	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vspart_02218	COG1263	PTS System
Vspart_02219	COG0084	hydrolase, TatD family'
Vspart_02220	COG0470	DNA polymerase III
Vspart_02221	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Vspart_02222	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Vspart_02228	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Vspart_02231	COG1399	metal-binding, possibly nucleic acid-binding protein
Vspart_02232	COG0424	maF-like protein
Vspart_02233	COG0564	pseudouridine synthase activity
Vspart_02234	COG1530	ribonuclease E activity
Vspart_02235	COG0659	secondary active sulfate transmembrane transporter activity
Vspart_02236	COG1012	belongs to the aldehyde dehydrogenase family
Vspart_02236	COG1454	alcohol dehydrogenase
Vspart_02237	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Vspart_02238	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Vspart_02239	COG3081	Nucleoid-associated protein
Vspart_02240	COG3082	Protein of unknown function (DUF1414)
Vspart_02241	COG3083	sulfuric ester hydrolase activity
Vspart_02251	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vspart_02252	COG4597	amino acid ABC transporter
Vspart_02253	COG0765	amino acid transport
Vspart_02254	COG1126	abc transporter atp-binding protein
Vspart_02257	COG1280	lysine exporter protein (LysE YggA)
Vspart_02258	COG0252	asparaginase activity
Vspart_02262	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Vspart_02263	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vspart_02267	COG2272	Belongs to the type-B carboxylesterase lipase family
Vspart_02274	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Vspart_02275	COG0596	Alpha beta hydrolase
Vspart_02278	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vspart_02279	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vspart_02281	COG0318	PFAM AMP-dependent synthetase and ligase
Vspart_02287	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Vspart_02293	COG2205	protein histidine kinase activity
Vspart_02294	COG2204	response regulator
Vspart_02295	COG1136	(ABC) transporter
Vspart_02295	COG0577	efflux transmembrane transporter activity
Vspart_02296	COG1136	(ABC) transporter
Vspart_02296	COG0577	efflux transmembrane transporter activity
Vspart_02300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Vspart_02301	COG0842	Transport permease protein
Vspart_02302	COG1131	(ABC) transporter
Vspart_02306	COG0601	transmembrane transport
Vspart_02307	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Vspart_02310	COG1917	Cupin 2, conserved barrel domain protein
Vspart_02310	COG2207	Transcriptional regulator
Vspart_02312	COG2801	Transposase and inactivated derivatives
Vspart_02314	COG2130	NADP-dependent
Vspart_02316	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Vspart_02317	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Vspart_02323	COG0835	chemotaxis
Vspart_02325	COG1192	Involved in chromosome partitioning
Vspart_02326	COG2201	protein-glutamate methylesterase activity
Vspart_02327	COG0643	Histidine kinase
Vspart_02327	COG2198	Histidine kinase
Vspart_02327	COG0784	Response regulator, receiver
Vspart_02328	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
Vspart_02334	COG2062	phosphohistidine phosphatase, SixA
Vspart_02335	COG1025	Belongs to the peptidase M16 family
Vspart_02336	COG3102	Protein conserved in bacteria
Vspart_02342	COG1918	ferrous iron import across plasma membrane
Vspart_02343	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
Vspart_02344	COG1121	(ABC) transporter
Vspart_02345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Vspart_02346	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Vspart_02349	COG0508	dehydrogenase complex catalyzes the overall conversion of
Vspart_02350	COG0567	Dehydrogenase, E1 component
Vspart_02352	COG1053	succinate dehydrogenase
Vspart_02353	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
Vspart_02354	COG2009	succinate dehydrogenase
Vspart_02356	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Vspart_02358	COG0033	Phosphoglucomutase
Vspart_02359	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
Vspart_02360	COG0596	Alpha beta hydrolase
Vspart_02361	COG0716	FMN binding
Vspart_02362	COG0735	belongs to the Fur family
Vspart_02363	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Vspart_02364	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Vspart_02365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Vspart_02366	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Vspart_02366	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Vspart_02367	COG0431	NADPH-dependent FMN reductase
Vspart_02369	COG3101	peptidyl-lysine hydroxylation
Vspart_02370	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Vspart_02371	COG2890	protein-(glutamine-N5) methyltransferase activity
Vspart_02372	COG2840	Smr protein MutS2
Vspart_02374	COG1684	flagellar biosynthetic protein fliR
Vspart_02375	COG1987	bacterial-type flagellum assembly
Vspart_02380	COG1580	Controls the rotational direction of flagella during chemotaxis
Vspart_02385	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Vspart_02387	COG1677	Flagellar hook-basal body complex protein FliE
Vspart_02389	COG4191	Histidine kinase
Vspart_02391	COG1516	flagellar protein fliS
Vspart_02393	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Vspart_02394	COG1334	flagellar protein FlaG
Vspart_02396	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vspart_02398	COG2837	iron assimilation
Vspart_02399	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Vspart_02401	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Vspart_02402	COG1136	(ABC) transporter
Vspart_02402	COG0577	efflux transmembrane transporter activity
Vspart_02404	COG0577	efflux transmembrane transporter activity
Vspart_02407	COG0672	)-iron permease
Vspart_02409	COG1393	Belongs to the ArsC family
Vspart_02411	COG1876	peptidase activity
Vspart_02413	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
Vspart_02414	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Vspart_02415	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Vspart_02418	COG4783	chaperone-mediated protein folding
Vspart_02419	COG1393	Belongs to the ArsC family
Vspart_02423	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Vspart_02424	COG0737	Belongs to the 5'-nucleotidase family
Vspart_02425	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Vspart_02426	COG2912	Transglutaminase-like superfamily
Vspart_02427	COG3094	Invasion gene expression up-regulator, SirB
Vspart_02428	COG2890	protein-(glutamine-N5) methyltransferase activity
Vspart_02429	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Vspart_02431	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
Vspart_02433	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Vspart_02434	COG0193	aminoacyl-tRNA hydrolase activity
Vspart_02451	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vspart_02453	COG1705	Flagellar rod assembly protein muramidase FlgJ
Vspart_02453	COG3951	Flagellar rod assembly protein muramidase FlgJ
Vspart_02455	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Vspart_02457	COG4787	bacterial-type flagellum-dependent cell motility
Vspart_02458	COG1749	Flagellar hook protein flgE
Vspart_02461	COG1815	bacterial-type flagellum-dependent cell motility
Vspart_02462	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Vspart_02463	COG0784	Response regulator, receiver
Vspart_02463	COG0835	chemotaxis
Vspart_02472	COG3047	cAMP biosynthetic process
Vspart_02475	COG1846	Transcriptional regulator
Vspart_02479	COG2217	Heavy metal translocating P-type atpase
Vspart_02479	COG2608	mercury ion transmembrane transporter activity
Vspart_02480	COG3735	TraB family
Vspart_02482	COG2840	Smr protein MutS2
Vspart_02483	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Vspart_02484	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Vspart_02485	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Vspart_02488	COG1051	belongs to the nudix hydrolase family
Vspart_02489	COG0121	glutamine amidotransferase
Vspart_02490	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Vspart_02494	COG0328	RNA-DNA hybrid ribonuclease activity
Vspart_02495	COG2226	methyltransferase
Vspart_02496	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Vspart_02497	COG1388	LysM domain
Vspart_02497	COG0741	lytic transglycosylase activity
Vspart_02502	COG0825	malonyl-CoA metabolic process
Vspart_02503	COG0587	DNA-directed DNA polymerase activity
Vspart_02504	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Vspart_02506	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Vspart_02507	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Vspart_02508	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Vspart_02509	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
Vspart_02511	COG0750	zinc metalloprotease
Vspart_02512	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Vspart_02513	COG0575	Belongs to the CDS family
Vspart_02514	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Vspart_02516	COG0528	UMP kinase activity
Vspart_02517	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Vspart_02518	COG0052	Belongs to the universal ribosomal protein uS2 family
Vspart_02520	COG0024	Methionine aminopeptidase
Vspart_02523	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Vspart_02524	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Vspart_02525	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Vspart_02529	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Vspart_02529	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Vspart_02530	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Vspart_02535	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Vspart_02536	COG2252	PERMEase
Vspart_02537	COG2195	Cleaves the N-terminal amino acid of tripeptides
Vspart_02538	COG4067	protein conserved in archaea
Vspart_02538	COG0189	ligase activity
Vspart_02539	COG0189	ligase activity
Vspart_02540	COG0733	neurotransmitter:sodium symporter activity
Vspart_02541	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Vspart_02542	COG0697	spore germination
Vspart_02543	COG0583	DNA-binding transcription factor activity
Vspart_02551	COG1805	sodium ion transport
Vspart_02552	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Vspart_02553	COG0271	Belongs to the BolA IbaG family
Vspart_02558	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Vspart_02560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Vspart_02561	COG2166	iron-sulfur cluster assembly
Vspart_02562	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Vspart_02563	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
Vspart_02564	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Vspart_02564	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Vspart_02566	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Vspart_02567	COG1074	ATP-dependent DNA helicase activity
Vspart_02568	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
Vspart_02569	COG0583	DNA-binding transcription factor activity
Vspart_02570	COG3141	response to X-ray
Vspart_02571	COG2171	N-acyltransferase activity
Vspart_02572	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Vspart_02574	COG1609	Transcriptional regulator
Vspart_02575	COG3437	response regulator, receiver
Vspart_02576	COG1022	Amp-dependent synthetase and ligase
Vspart_02578	COG0583	DNA-binding transcription factor activity
Vspart_02579	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Vspart_02580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Vspart_02582	COG0560	Phosphoserine phosphatase
Vspart_02584	COG0813	purine-nucleoside phosphorylase activity
Vspart_02585	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Vspart_02586	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Vspart_02587	COG0084	hydrolase, TatD family'
Vspart_02589	COG3022	response to hydroperoxide
Vspart_02590	COG1115	amino acid carrier protein
Vspart_02593	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Vspart_02595	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
Vspart_02596	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Vspart_02597	COG0083	homoserine kinase activity
Vspart_02600	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Vspart_02602	COG0745	RESPONSE REGULATOR receiver
Vspart_02603	COG2198	Histidine kinase
Vspart_02603	COG5002	protein histidine kinase activity
Vspart_02603	COG0784	Response regulator, receiver
Vspart_02604	COG2203	Gaf domain
Vspart_02604	COG3706	GGDEF domain
Vspart_02604	COG4251	negative regulation of phosphorylation
Vspart_02604	COG5001	Diguanylate cyclase
Vspart_02605	COG1242	4 iron, 4 sulfur cluster binding
Vspart_02606	COG0070	glutamate synthase
Vspart_02606	COG0067	glutamate synthase
Vspart_02606	COG0069	glutamate synthase activity
Vspart_02608	COG0067	glutamate synthase
Vspart_02608	COG0069	glutamate synthase activity
Vspart_02608	COG0070	glutamate synthase
Vspart_02609	COG0493	'glutamate synthase
Vspart_02610	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Vspart_02612	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Vspart_02613	COG2860	membrane
Vspart_02614	COG0583	DNA-binding transcription factor activity
Vspart_02615	COG0730	response to heat
Vspart_02616	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Vspart_02617	COG0505	Belongs to the CarA family
Vspart_02618	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Vspart_02619	COG0494	nUDIX hydrolase
Vspart_02620	COG0653	protein targeting
Vspart_02622	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Vspart_02623	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Vspart_02624	COG0849	cell division
Vspart_02625	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Vspart_02626	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Vspart_02628	COG0772	Belongs to the SEDS family
Vspart_02629	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Vspart_02631	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Vspart_02632	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Vspart_02633	COG0768	penicillin binding
Vspart_02634	COG3116	cell division
Vspart_02637	COG0534	Mate efflux family protein
Vspart_02639	COG0840	transmembrane signaling receptor activity
Vspart_02640	COG3971	2-oxopent-4-enoate hydratase activity
Vspart_02641	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Vspart_02642	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Vspart_02646	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_02647	COG1012	belongs to the aldehyde dehydrogenase family
Vspart_02648	COG0028	Belongs to the TPP enzyme family
Vspart_02651	COG2423	ornithine cyclodeaminase activity
Vspart_02656	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Vspart_02657	COG3107	peptidoglycan biosynthetic process
Vspart_02659	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Vspart_02660	COG2823	Periplasmic or secreted lipoprotein
Vspart_02661	COG2969	positive regulation of protein catabolic process
Vspart_02662	COG0625	glutathione transferase activity
Vspart_02663	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Vspart_02664	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Vspart_02665	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Vspart_02666	COG3105	Protein conserved in bacteria
Vspart_02667	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Vspart_02668	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Vspart_02669	COG0335	large ribosomal subunit rRNA binding
Vspart_02671	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Vspart_02673	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Vspart_02674	COG4137	Cytochrome C assembly protein
Vspart_02675	COG4536	flavin adenine dinucleotide binding
Vspart_02677	COG2918	glutathione biosynthetic process
Vspart_02679	COG0612	Peptidase, M16
Vspart_02680	COG1238	metal cluster binding
Vspart_02681	COG1063	alcohol dehydrogenase
Vspart_02682	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
Vspart_02684	COG3630	sodium ion export across plasma membrane
Vspart_02691	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Vspart_02692	COG0527	aspartate kinase activity
Vspart_02693	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Vspart_02695	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Vspart_02696	COG1546	Belongs to the CinA family
Vspart_02697	COG1414	Transcriptional regulator
Vspart_02698	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_02699	COG1917	Cupin 2, conserved barrel domain protein
Vspart_02702	COG0800	Aldolase
Vspart_02705	COG3842	ATPase activity
Vspart_02706	COG0395	ABC-type sugar transport system, permease component
Vspart_02707	COG1175	transmembrane transport
Vspart_02710	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Vspart_02711	COG0823	Involved in the tonB-independent uptake of proteins
Vspart_02712	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Vspart_02713	COG3437	response regulator, receiver
Vspart_02713	COG0784	Response regulator, receiver
Vspart_02714	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vspart_02714	COG4191	Histidine kinase
Vspart_02716	COG5297	Belongs to the glycosyl hydrolase family 6
Vspart_02717	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Vspart_02718	COG4942	peptidase
Vspart_02718	COG1388	LysM domain
Vspart_02720	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Vspart_02721	COG0585	pseudouridine synthase activity
Vspart_02723	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Vspart_02724	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
Vspart_02725	COG1968	undecaprenyl-diphosphatase activity
Vspart_02726	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Vspart_02727	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Vspart_02731	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Vspart_02732	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Vspart_02733	COG1610	YqeY-like protein
Vspart_02734	COG0358	DNA primase activity
Vspart_02745	COG1940	carbohydrate kinase activity
Vspart_02746	COG4821	SIS domain
Vspart_02747	COG0383	alpha-mannosidase activity
Vspart_02749	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vspart_02749	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vspart_02755	COG1368	sulfuric ester hydrolase activity
Vspart_02757	COG0604	alcohol dehydrogenase
Vspart_02768	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vspart_02807	COG2204	response regulator
Vspart_02809	COG0840	transmembrane signaling receptor activity
Vspart_02811	COG2814	Major facilitator Superfamily
Vspart_02817	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vspart_02821	COG2205	protein histidine kinase activity
Vspart_02822	COG0745	RESPONSE REGULATOR receiver
Vspart_02827	COG2217	Heavy metal translocating P-type atpase
Vspart_02828	COG0789	Transcriptional regulator
Vspart_02831	COG3344	reverse transcriptase
Vspart_02834	COG2801	Transposase and inactivated derivatives
Vspart_02839	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Vspart_02840	COG1349	DNA-binding transcription factor activity
Vspart_02841	COG0469	pyruvate kinase activity
Vspart_02843	COG0668	transmembrane transport
Vspart_02846	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Vspart_02847	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Vspart_02848	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Vspart_02849	COG3091	SprT-like family
Vspart_02850	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Vspart_02851	COG0189	ligase activity
Vspart_02852	COG1678	Uncharacterized ACR, COG1678
Vspart_02853	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Vspart_02855	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Vspart_02856	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Vspart_02857	COG0762	integral membrane protein
Vspart_02858	COG1872	DUF167
Vspart_02860	COG3437	response regulator, receiver
Vspart_02863	COG2172	sigma factor antagonist activity
Vspart_02865	COG1366	Belongs to the anti-sigma-factor antagonist family
Vspart_02867	COG3040	lipid binding
Vspart_02874	COG3209	COG3209 Rhs family protein
Vspart_02879	COG3209	COG3209 Rhs family protein
Vspart_02886	COG3501	Rhs element vgr protein
Vspart_02887	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Vspart_02888	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Vspart_02890	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Vspart_02892	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
Vspart_02903	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
Vspart_02904	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Vspart_02905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Vspart_02906	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Vspart_02907	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Vspart_02908	COG2967	ApaG domain
Vspart_02909	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Vspart_02911	COG3610	response to peptide
Vspart_02912	COG2966	Psort location CytoplasmicMembrane, score
Vspart_02913	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Vspart_02916	COG0142	geranyltranstransferase activity
Vspart_02919	COG0039	L-malate dehydrogenase activity
Vspart_02920	COG1438	arginine binding
Vspart_02921	COG2358	TRAP transporter, solute receptor (TAXI family
Vspart_02923	COG0589	response to stress
Vspart_02926	COG2186	Transcriptional regulator
Vspart_02928	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Vspart_02931	COG0246	Mannitol dehydrogenase
Vspart_02933	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vspart_02934	COG0800	Aldolase
Vspart_02939	COG0633	Ferredoxin
Vspart_02941	COG0697	spore germination
Vspart_02947	COG0395	ABC-type sugar transport system, permease component
Vspart_02948	COG1175	transmembrane transport
Vspart_02953	COG0312	modulator of DNA gyrase
Vspart_02954	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Vspart_02955	COG3164	Protein of unknown function
Vspart_02956	COG1530	ribonuclease E activity
Vspart_02957	COG0424	maF-like protein
Vspart_02958	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
Vspart_02959	COG1792	Involved in formation and maintenance of cell shape
Vspart_02960	COG1077	Cell shape determining protein MreB Mrl
Vspart_02961	COG2200	EAL domain
Vspart_02961	COG2199	diguanylate cyclase activity
Vspart_02963	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Vspart_02965	COG0309	Hydrogenase expression formation protein (HypE)
Vspart_02967	COG0298	carbon dioxide binding
Vspart_02968	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Vspart_02970	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Vspart_02972	COG3383	formate dehydrogenase (NAD+) activity
Vspart_02973	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Vspart_02974	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
Vspart_02976	COG3260	NADH ubiquinone oxidoreductase 20
Vspart_02977	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Vspart_02978	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
Vspart_02978	COG3261	NADH dehydrogenase
Vspart_02979	COG0651	ATP synthesis coupled electron transport
Vspart_02980	COG4237	Hydrogenase 4 membrane
Vspart_02981	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Vspart_02982	COG0650	Formate hydrogenlyase subunit 4
Vspart_02983	COG0651	ATP synthesis coupled electron transport
Vspart_02984	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Vspart_02985	COG0527	aspartate kinase activity
Vspart_02987	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Vspart_02989	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Vspart_02992	COG0629	single-stranded DNA binding
Vspart_02993	COG0646	methionine synthase
Vspart_02993	COG1410	methionine synthase
Vspart_03008	COG0175	sulfate reduction
Vspart_03009	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Vspart_03018	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Vspart_03022	COG5433	transposase activity
Vspart_03023	COG5433	transposase activity
Vspart_03024	COG0583	DNA-binding transcription factor activity
Vspart_03025	COG1942	4-Oxalocrotonate Tautomerase
Vspart_03026	COG0697	spore germination
Vspart_03036	COG0693	protein deglycase activity
Vspart_03045	COG0735	belongs to the Fur family
Vspart_03049	COG0305	Participates in initiation and elongation during chromosome replication
Vspart_03052	COG0359	binds to the 23S rRNA
Vspart_03053	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Vspart_03054	COG2965	DNA replication, synthesis of RNA primer
Vspart_03055	COG0360	Binds together with S18 to 16S ribosomal RNA
Vspart_03059	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Vspart_03060	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Vspart_03061	COG0049	tRNA binding
Vspart_03065	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
Vspart_03066	COG2964	Protein conserved in bacteria
Vspart_03067	COG0545	Peptidyl-prolyl cis-trans isomerase
Vspart_03070	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
Vspart_03071	COG0330	HflC and HflK could
Vspart_03072	COG0330	HflC and HflK could
Vspart_03073	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Vspart_03074	COG1923	regulation of RNA biosynthetic process
Vspart_03075	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Vspart_03076	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Vspart_03077	COG0860	N-Acetylmuramoyl-L-alanine amidase
Vspart_03078	COG0802	atpase or kinase
Vspart_03079	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Vspart_03087	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
Vspart_03088	COG1162	GTPase activity
Vspart_03089	COG0688	phosphatidylethanolamine metabolic process
Vspart_03090	COG0471	metal ion transport
Vspart_03093	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Vspart_03094	COG4942	peptidase
Vspart_03096	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Vspart_03097	COG2816	NAD+ diphosphatase activity
Vspart_03098	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
Vspart_03099	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Vspart_03100	COG0085	RNA polymerase activity
Vspart_03102	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Vspart_03103	COG0081	regulation of translation
Vspart_03104	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Vspart_03105	COG0250	Participates in transcription elongation, termination and antitermination
Vspart_03106	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Vspart_03107	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Vspart_03112	COG1072	(Pantothenic acid kinase))
Vspart_03114	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Vspart_03116	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Vspart_03119	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Vspart_03122	COG3118	belongs to the thioredoxin family
Vspart_03123	COG0513	Belongs to the DEAD box helicase family
Vspart_03124	COG0248	Ppx GppA phosphatase
Vspart_03125	COG0784	Response regulator, receiver
Vspart_03125	COG2198	Histidine kinase
Vspart_03125	COG2205	protein histidine kinase activity
Vspart_03126	COG2188	Transcriptional regulator
Vspart_03129	COG2814	Major facilitator Superfamily
Vspart_03132	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Vspart_03133	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Vspart_03134	COG0511	ligase activity, forming carbon-carbon bonds
Vspart_03135	COG0439	Biotin carboxylase
Vspart_03136	COG2264	protein methyltransferase activity
Vspart_03140	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_03141	COG1733	regulation of RNA biosynthetic process
Vspart_03142	COG0840	transmembrane signaling receptor activity
Vspart_03147	COG0138	bifunctional purine biosynthesis protein purh
Vspart_03148	COG0151	Belongs to the GarS family
Vspart_03150	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Vspart_03151	COG2183	response to ionizing radiation
Vspart_03153	COG0596	Alpha beta hydrolase
Vspart_03154	COG1040	competence protein
Vspart_03155	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Vspart_03155	COG0316	Belongs to the HesB IscA family
Vspart_03156	COG0494	nUDIX hydrolase
Vspart_03157	COG1218	3'(2'),5'-bisphosphate nucleotidase
Vspart_03159	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
Vspart_03160	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
Vspart_03161	COG3156	type II secretion system protein K
Vspart_03162	COG4795	General secretion pathway protein
Vspart_03163	COG2165	general secretion pathway protein
Vspart_03164	COG2165	general secretion pathway protein
Vspart_03165	COG2165	general secretion pathway protein
Vspart_03166	COG1459	type II secretion system
Vspart_03167	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Vspart_03169	COG3031	protein transport across the cell outer membrane
Vspart_03170	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Vspart_03171	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Vspart_03172	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Vspart_03174	COG0456	acetyltransferase
Vspart_03175	COG1490	D-aminoacyl-tRNA deacylase activity
Vspart_03176	COG1295	ribonuclease BN
Vspart_03178	COG0174	glutamine synthetase
Vspart_03179	COG3852	Histidine kinase
Vspart_03180	COG2204	response regulator
Vspart_03192	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Vspart_03193	COG4206	TonB-dependent receptor
Vspart_03199	COG0477	Major facilitator Superfamily
Vspart_03202	COG3501	Rhs element vgr protein
Vspart_03220	COG2084	Dehydrogenase
Vspart_03221	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vspart_03222	COG1349	DNA-binding transcription factor activity
Vspart_03231	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Vspart_03232	COG0583	DNA-binding transcription factor activity
Vspart_03235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Vspart_03236	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Vspart_03237	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Vspart_03238	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Vspart_03240	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Vspart_03241	COG3161	chorismate lyase activity
Vspart_03243	COG0705	Rhomboid family
Vspart_03246	COG2177	Part of the ABC transporter FtsEX involved in
Vspart_03247	COG2884	Cell division ATP-binding protein ftsE
Vspart_03248	COG0552	protein localization to endoplasmic reticulum
Vspart_03249	COG0742	ribosomal rna small subunit methyltransferase
Vspart_03250	COG2095	MarC family integral membrane protein
Vspart_03255	COG0783	Belongs to the Dps family
Vspart_03256	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
Vspart_03257	COG1280	lysine exporter protein (LysE YggA)
Vspart_03258	COG2267	carboxylic ester hydrolase activity
Vspart_03259	COG0561	phosphatase activity
Vspart_03260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vspart_03262	COG2977	Belongs to the P-Pant transferase superfamily
Vspart_03266	COG1011	Hydrolase
Vspart_03267	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Vspart_03270	COG0019	diaminopimelate decarboxylase activity
Vspart_03275	COG2959	enzyme of heme biosynthesis
Vspart_03276	COG3071	HemY protein
Vspart_03279	COG3078	GTPase activator activity
Vspart_03284	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Vspart_03284	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Vspart_03286	COG0084	hydrolase, TatD family'
Vspart_03287	COG0583	DNA-binding transcription factor activity
Vspart_03288	COG2249	NAD(P)H dehydrogenase (quinone) activity
Vspart_03289	COG0805	protein transport
Vspart_03290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Vspart_03291	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Vspart_03292	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Vspart_03293	COG3165	ubiquinone biosynthetic process from chorismate
Vspart_03294	COG2226	methyltransferase
Vspart_03295	COG1322	Protein conserved in bacteria
Vspart_03301	COG2160	L-arabinose isomerase activity
Vspart_03304	COG1069	ribulokinase activity
Vspart_03305	COG1879	ABC-type sugar transport system periplasmic component
Vspart_03306	COG1129	ABC transporter
Vspart_03307	COG1172	Belongs to the binding-protein-dependent transport system permease family
Vspart_03308	COG2329	Antibiotic biosynthesis monooxygenase
Vspart_03317	COG0583	DNA-binding transcription factor activity
Vspart_03320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vspart_03321	COG0028	Belongs to the TPP enzyme family
Vspart_03323	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Vspart_03323	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Vspart_03330	COG2378	regulation of single-species biofilm formation
Vspart_03350	COG0702	epimerase
Vspart_03352	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Vspart_03358	COG1468	defense response to virus
Vspart_03358	COG1518	maintenance of DNA repeat elements
Vspart_03367	COG2188	Transcriptional regulator
Vspart_03368	COG1070	Carbohydrate kinase
Vspart_03369	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Vspart_03376	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Vspart_03384	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Vspart_03386	COG2081	HI0933 family
Vspart_03388	COG1528	Iron-storage protein
Vspart_03392	COG0742	ribosomal rna small subunit methyltransferase
Vspart_03393	COG1522	sequence-specific DNA binding
Vspart_03395	COG0006	proline dipeptidase activity
Vspart_03401	COG4175	Glycine betaine
Vspart_03402	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Vspart_03403	COG2022	thiamine diphosphate biosynthetic process
Vspart_03404	COG2104	thiamine diphosphate biosynthetic process
Vspart_03405	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Vspart_03406	COG0352	thiamine-phosphate diphosphorylase activity
Vspart_03410	COG3940	Belongs to the glycosyl hydrolase 43 family
Vspart_03411	COG2211	Major facilitator Superfamily
Vspart_03419	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
Vspart_03420	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Vspart_03421	COG1739	Uncharacterized protein family UPF0029
Vspart_03425	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Vspart_03426	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Vspart_03427	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Vspart_03428	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Vspart_03429	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Vspart_03430	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Vspart_03432	COG0356	it plays a direct role in the translocation of protons across the membrane
Vspart_03434	COG1475	DNA binding
Vspart_03435	COG1192	Involved in chromosome partitioning
Vspart_03437	COG0445	tRNA wobble uridine modification
Vspart_03438	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Vspart_03447	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Vspart_03448	COG0706	membrane insertase activity
Vspart_03449	COG0594	ribonuclease P activity
Vspart_03451	COG1126	abc transporter atp-binding protein
Vspart_03455	COG1444	tRNA N-acetyltransferase activity
Vspart_03460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vspart_03462	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Vspart_03469	COG3722	fumarate hydratase activity
Vspart_03471	COG2213	PTS system mannitol-specific
Vspart_03471	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vspart_03473	COG3085	chromosome segregation
Vspart_03475	COG2259	Doxx family
Vspart_03477	COG0840	transmembrane signaling receptor activity
Vspart_03482	COG2272	Belongs to the type-B carboxylesterase lipase family
Vspart_03486	COG0583	DNA-binding transcription factor activity
Vspart_03488	COG1940	carbohydrate kinase activity
Vspart_03489	COG0191	fructose-bisphosphate aldolase activity
Vspart_03490	COG0191	fructose-bisphosphate aldolase activity
Vspart_03491	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vspart_03491	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vspart_03491	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
Vspart_03492	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vspart_03492	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vspart_03492	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vspart_03494	COG3711	transcriptional antiterminator
Vspart_03500	COG1794	racemase activity, acting on amino acids and derivatives
Vspart_03503	COG2873	o-acetylhomoserine
Vspart_03505	COG1280	lysine exporter protein (LysE YggA)
Vspart_03506	COG3693	PFAM glycoside hydrolase, family 10
Vspart_03506	COG3509	depolymerase
Vspart_03512	COG0456	acetyltransferase
Vspart_03512	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Vspart_03533	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Vspart_03536	COG0151	Belongs to the GarS family
Vspart_03548	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
Vspart_03549	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vspart_03550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vspart_03551	COG1120	ATPase activity
Vspart_03553	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Vspart_03554	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Vspart_03555	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
Vspart_03556	COG0247	lactate metabolic process
Vspart_03558	COG1609	Transcriptional regulator
Vspart_03579	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Vspart_03580	COG1063	alcohol dehydrogenase
Vspart_03581	COG2186	Transcriptional regulator
Vspart_03582	COG4948	Mandelate Racemase Muconate Lactonizing
Vspart_03583	COG0246	Mannitol dehydrogenase
Vspart_03595	COG1518	maintenance of DNA repeat elements
Vspart_03595	COG1468	defense response to virus
Vspart_03604	COG1605	Chorismate mutase
Vspart_03607	COG1139	Iron-sulfur cluster binding protein
Vspart_03609	COG1620	l-lactate permease
Vspart_03610	COG0583	DNA-binding transcription factor activity
Vspart_03612	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Vspart_03614	COG0471	metal ion transport
Vspart_03615	COG1051	belongs to the nudix hydrolase family
Vspart_03625	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Vspart_03628	COG0346	lactoylglutathione lyase activity
Vspart_03632	COG2814	Major facilitator Superfamily
Vspart_03637	COG2771	luxR family
Vspart_03640	COG2207	Transcriptional regulator
Vspart_03641	COG4773	Receptor
Vspart_03644	COG2723	6-phospho-beta-galactosidase activity
Vspart_03645	COG1263	PTS System
Vspart_03645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vspart_03646	COG3265	gluconokinase activity
Vspart_03647	COG1609	Transcriptional regulator
Vspart_03649	COG4399	Belongs to the UPF0754 family
Vspart_03650	COG1132	(ABC) transporter
Vspart_03653	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
Vspart_03656	COG3706	GGDEF domain
Vspart_03659	COG3272	Protein of unknown function (DUF1722)
Vspart_03660	COG0789	Transcriptional regulator
Vspart_03661	COG0415	Belongs to the DNA photolyase family
Vspart_03662	COG1376	ErfK ybiS ycfS ynhG family protein
Vspart_03662	COG1388	LysM domain
Vspart_03664	COG0513	Belongs to the DEAD box helicase family
Vspart_03666	COG0840	transmembrane signaling receptor activity
Vspart_03669	COG0573	inorganic phosphate transmembrane transporter activity
Vspart_03670	COG0581	inorganic phosphate transmembrane transporter activity
Vspart_03671	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Vspart_03675	COG0739	heme binding
Vspart_03676	COG5001	Diguanylate cyclase
Vspart_03678	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Vspart_03679	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
Vspart_03680	COG2814	Major facilitator Superfamily
Vspart_03681	COG0583	DNA-binding transcription factor activity
Vspart_03682	COG0667	Aldo Keto reductase
Vspart_03683	COG0583	DNA-binding transcription factor activity
Vspart_03684	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vspart_03688	COG0179	Fumarylacetoacetate (FAA) hydrolase
Vspart_03689	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Vspart_03691	COG2190	(PTS) system
Vspart_03691	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vspart_03691	COG1263	PTS System
Vspart_03692	COG1263	PTS System
Vspart_03692	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vspart_03692	COG2190	(PTS) system
Vspart_03693	COG3711	transcriptional antiterminator
Vspart_03694	COG2723	6-phospho-beta-galactosidase activity
Vspart_03697	COG2095	MarC family integral membrane protein
Vspart_03701	COG0384	phenazine biosynthesis protein PhzF
Vspart_03704	COG0604	alcohol dehydrogenase
Vspart_03709	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Vspart_03710	COG2267	carboxylic ester hydrolase activity
Vspart_03711	COG1979	alcohol dehydrogenase
Vspart_03712	COG1357	PFAM Pentapeptide repeats (8 copies)
Vspart_03725	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Vspart_03726	COG2194	sulfuric ester hydrolase activity
Vspart_03727	COG5002	protein histidine kinase activity
Vspart_03728	COG0745	RESPONSE REGULATOR receiver
Vspart_03731	COG0534	Mate efflux family protein
Vspart_03734	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Vspart_03737	COG2205	protein histidine kinase activity
Vspart_03737	COG0784	Response regulator, receiver
Vspart_03737	COG5002	protein histidine kinase activity
Vspart_03740	COG1765	OsmC-like protein
Vspart_03742	COG2354	Protein conserved in bacteria
Vspart_03747	COG0418	dihydroorotase activity
Vspart_03755	COG0840	transmembrane signaling receptor activity
Vspart_03756	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Vspart_03756	COG0646	methionine synthase
Vspart_03758	COG0840	transmembrane signaling receptor activity
Vspart_03761	COG2814	Major facilitator Superfamily
Vspart_03762	COG1522	sequence-specific DNA binding
Vspart_03769	COG0456	acetyltransferase
Vspart_03771	COG0189	ligase activity
Vspart_03771	COG0569	domain protein
Vspart_03775	COG0363	glucosamine-6-phosphate deaminase activity
Vspart_03776	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Vspart_03777	COG3437	response regulator, receiver
Vspart_03780	COG2991	Protein conserved in bacteria
Vspart_03781	COG0673	inositol 2-dehydrogenase activity
Vspart_03785	COG1064	alcohol dehydrogenase
Vspart_03786	COG4305	rare lipoprotein A
Vspart_03790	COG3724	N-succinylarginine dihydrolase activity
Vspart_03791	COG2988	succinylglutamate desuccinylase activity
Vspart_03792	COG3706	GGDEF domain
Vspart_03793	COG5002	protein histidine kinase activity
Vspart_03800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vspart_03802	COG0156	8-amino-7-oxononanoate synthase activity
Vspart_03803	COG0784	Response regulator, receiver
Vspart_03803	COG2205	protein histidine kinase activity
Vspart_03804	COG3501	Rhs element vgr protein
Vspart_03813	COG1335	isochorismatase
Vspart_03814	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Vspart_03814	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Vspart_03815	COG0509	glycine decarboxylation via glycine cleavage system
Vspart_03817	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Vspart_03819	COG5001	Diguanylate cyclase
Vspart_03819	COG3300	MHYT domain
Vspart_03822	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Vspart_03823	COG0840	transmembrane signaling receptor activity
Vspart_03824	COG1609	Transcriptional regulator
Vspart_03828	COG2723	6-phospho-beta-galactosidase activity
Vspart_03829	COG3842	ATPase activity
Vspart_03830	COG3459	Glycosyltransferase 36 associated
Vspart_03832	COG1609	Transcriptional regulator
Vspart_03833	COG5297	Belongs to the glycosyl hydrolase family 6
Vspart_03833	COG2273	Hydrolase Family 16
Vspart_03840	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Vspart_03842	COG4181	ATPase activity
Vspart_03844	COG2095	MarC family integral membrane protein
Vspart_03846	COG5297	Belongs to the glycosyl hydrolase family 6
Vspart_03846	COG2273	Hydrolase Family 16
Vspart_03852	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Vspart_03853	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Vspart_03857	COG2425	protein containing a von Willebrand factor type A (vWA) domain
Vspart_03858	COG3713	MltA-interacting MipA family protein
Vspart_03859	COG1584	GPR1 FUN34 yaaH family protein
Vspart_03860	COG0625	glutathione transferase activity
Vspart_03866	COG0494	nUDIX hydrolase
Vspart_03867	COG0678	peroxiredoxin activity
Vspart_03871	COG3132	Protein of unknown function, DUF480
Vspart_03874	COG1879	ABC-type sugar transport system periplasmic component
Vspart_03875	COG0784	Response regulator, receiver
Vspart_03875	COG5002	protein histidine kinase activity
Vspart_03877	COG1492	cobalamin metabolic process
Vspart_03880	COG1289	transmembrane transporter activity
Vspart_03881	COG0210	DNA helicase
Vspart_03882	COG1803	Methylglyoxal synthase
Vspart_03883	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Vspart_03886	COG0183	Belongs to the thiolase family
Vspart_03889	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Vspart_03890	COG0523	cobalamin synthesis protein
Vspart_03892	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Vspart_03895	COG0513	Belongs to the DEAD box helicase family
Vspart_03896	COG0840	transmembrane signaling receptor activity
Vspart_03897	COG2723	6-phospho-beta-galactosidase activity
Vspart_03901	COG3300	MHYT domain
Vspart_03901	COG5001	Diguanylate cyclase
Vspart_03902	COG2816	NAD+ diphosphatase activity
Vspart_03903	COG0488	(ABC) transporter
Vspart_03904	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Vspart_03906	COG4943	cyclic-guanylate-specific phosphodiesterase activity
Vspart_03909	COG3507	Belongs to the glycosyl hydrolase 43 family
Vspart_03910	COG1203	CRISPR-associated helicase, Cas3
Vspart_03916	COG1518	maintenance of DNA repeat elements
Vspart_03917	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Vspart_03918	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Vspart_03918	COG3153	acetyltransferase
Vspart_03920	COG0513	Belongs to the DEAD box helicase family
Vspart_03921	COG0513	Belongs to the DEAD box helicase family
Vspart_03925	COG0243	molybdopterin cofactor binding
Vspart_03928	COG3634	alkyl hydroperoxide reductase activity
Vspart_03930	COG1063	alcohol dehydrogenase
Vspart_03937	COG1328	CTP reductase activity
Vspart_03938	COG0602	queuosine metabolic process
Vspart_03940	COG1538	Outer membrane efflux protein
Vspart_03942	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vspart_03945	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
Vspart_03947	COG0402	S-adenosylhomocysteine deaminase activity
Vspart_03948	COG2351	hydroxyisourate hydrolase activity
Vspart_03950	COG3608	succinylglutamate desuccinylase aspartoacylase
Vspart_03950	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Vspart_03956	COG1129	ABC transporter
Vspart_03957	COG1309	transcriptional regulator
Vspart_03960	COG3300	MHYT domain
Vspart_03960	COG5001	Diguanylate cyclase
Vspart_03963	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Vspart_03966	COG2207	Transcriptional regulator
Vspart_03968	COG1960	acyl-CoA dehydrogenase activity
Vspart_03974	COG2192	nodulation
Vspart_03979	COG3706	GGDEF domain
Vspart_03982	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Vspart_03983	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Vspart_03990	COG0023	Translation Initiation Factor
Vspart_03995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vspart_03995	COG1042	CoA-binding domain protein
Vspart_03995	COG0045	succinate-CoA ligase (ADP-forming) activity
Vspart_03996	COG0583	DNA-binding transcription factor activity
Vspart_03997	COG4533	DNA binding
Vspart_03998	COG2050	protein possibly involved in aromatic compounds catabolism
Vspart_03999	COG2824	Alkylphosphonate utilization operon protein PhnA
Vspart_04002	COG0737	Belongs to the 5'-nucleotidase family
Vspart_04003	COG3593	DNA synthesis involved in DNA repair
Vspart_04004	COG0583	DNA-binding transcription factor activity
Vspart_04005	COG2116	formate transmembrane transporter activity
Vspart_04006	COG2353	YceI-like domain
Vspart_04007	COG3038	cytochrome b561
Vspart_04010	COG4172	Belongs to the ABC transporter superfamily
Vspart_04011	COG4239	(ABC) transporter, permease
Vspart_04012	COG4174	ABC transporter (Permease)
Vspart_04013	COG4166	transmembrane transport
Vspart_04014	COG1051	belongs to the nudix hydrolase family
Vspart_04017	COG1011	Hydrolase
Vspart_04019	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
Vspart_04021	COG0302	gtp cyclohydrolase
Vspart_04023	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Vspart_04024	COG2897	thiosulfate sulfurtransferase activity
Vspart_04027	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Vspart_04029	COG0545	Peptidyl-prolyl cis-trans isomerase
Vspart_04030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Vspart_04034	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Vspart_04065	COG1396	sequence-specific DNA binding
Vspart_04068	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Vspart_04070	COG2515	1-aminocyclopropane-1-carboxylate deaminase
Vspart_04071	COG1522	sequence-specific DNA binding
Vspart_04074	COG1121	(ABC) transporter
Vspart_04075	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Vspart_04076	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Vspart_04077	COG2985	domain, Protein
Vspart_04078	COG1609	Transcriptional regulator
Vspart_04079	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vspart_04080	COG1879	ABC-type sugar transport system periplasmic component
Vspart_04081	COG1172	Belongs to the binding-protein-dependent transport system permease family
Vspart_04083	COG1869	D-ribose catabolic process
Vspart_04085	COG3409	Peptidoglycan-binding domain 1 protein
Vspart_04085	COG3757	hydrolase, family 25
Vspart_04106	COG2828	Protein conserved in bacteria
Vspart_04108	COG0642	Histidine kinase
Vspart_04109	COG0745	RESPONSE REGULATOR receiver
Vspart_04113	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Vspart_04114	COG0626	cystathionine gamma-synthase activity
Vspart_04118	COG1609	Transcriptional regulator
Vspart_04120	COG1105	Belongs to the carbohydrate kinase PfkB family
Vspart_04121	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
Vspart_04121	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vspart_04121	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vspart_04122	COG3693	PFAM glycoside hydrolase, family 10
Vspart_04124	COG1929	Belongs to the glycerate kinase type-1 family
Vspart_04127	COG1902	pentaerythritol trinitrate reductase activity
Vspart_04127	COG0446	pyridine nucleotide-disulphide oxidoreductase
Vspart_04129	COG4251	negative regulation of phosphorylation
Vspart_04132	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Vspart_04133	COG3104	oligopeptide transport
Vspart_04134	COG1070	Carbohydrate kinase
Vspart_04135	COG2207	Transcriptional regulator
Vspart_04135	COG1609	Transcriptional regulator
Vspart_04136	COG2814	Major facilitator Superfamily
Vspart_04136	COG0477	Major facilitator Superfamily
Vspart_04137	COG2115	Belongs to the xylose isomerase family
Vspart_04143	COG0840	transmembrane signaling receptor activity
Vspart_04149	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Vspart_04153	COG1737	Transcriptional regulator
Vspart_04154	COG1126	abc transporter atp-binding protein
Vspart_04155	COG0765	amino acid transport
Vspart_04156	COG0765	amino acid transport
Vspart_04157	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vspart_04160	COG1953	Uracil, thiamine, allantoin
Vspart_04163	COG3940	Belongs to the glycosyl hydrolase 43 family
Vspart_04170	COG3209	COG3209 Rhs family protein
Vspart_04174	COG0419	ATPase involved in DNA repair
Vspart_04179	COG0454	-acetyltransferase
Vspart_04188	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Vspart_04189	COG0659	secondary active sulfate transmembrane transporter activity
Vspart_04198	COG2017	converts alpha-aldose to the beta-anomer
Vspart_04202	COG1566	PFAM secretion protein HlyD family protein
Vspart_04203	COG1289	transmembrane transporter activity
Vspart_04206	COG2211	Major facilitator Superfamily
Vspart_04207	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Vspart_04209	COG3477	response to acidic pH
Vspart_04210	COG1012	belongs to the aldehyde dehydrogenase family
Vspart_04211	COG3284	Transcriptional regulator
Vspart_04212	COG1605	Chorismate mutase
Vspart_04212	COG0077	Prephenate dehydratase
Vspart_04214	COG1349	DNA-binding transcription factor activity
Vspart_04215	COG0584	glycerophosphoryl diester phosphodiesterase
Vspart_04217	COG1175	transmembrane transport
Vspart_04218	COG0395	ABC-type sugar transport system, permease component
Vspart_04219	COG3842	ATPase activity
Vspart_04221	COG0681	Belongs to the peptidase S26 family
Vspart_04224	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vspart_04225	COG0242	peptide deformylase activity
Vspart_04226	COG4115	mRNA cleavage
Vspart_04233	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Vspart_04244	COG1942	4-Oxalocrotonate Tautomerase
Vspart_04252	COG3730	PTS system glucitol sorbitol-specific
Vspart_04253	COG1349	DNA-binding transcription factor activity
Vspart_04254	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vspart_04255	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_04256	COG3731	PTS system glucitol sorbitol-specific IIA component
Vspart_04258	COG3730	PTS system glucitol sorbitol-specific
Vspart_04262	COG0840	transmembrane signaling receptor activity
Vspart_04269	COG0076	glutamate decarboxylase activity
Vspart_04271	COG2207	Transcriptional regulator
Vspart_04273	COG0747	negative chemotaxis
Vspart_04275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Vspart_04276	COG0444	Belongs to the ABC transporter superfamily
Vspart_04277	COG4608	Belongs to the ABC transporter superfamily
Vspart_04280	COG1028	Short-chain dehydrogenase reductase Sdr
Vspart_04283	COG1278	Cold shock
Vspart_04286	COG2194	sulfuric ester hydrolase activity
Vspart_04291	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Vspart_04293	COG3604	Transcriptional regulator
Vspart_04296	COG4106	trans-aconitate 2-methyltransferase activity
Vspart_04297	COG1280	lysine exporter protein (LysE YggA)
Vspart_04304	COG1846	Transcriptional regulator
Vspart_04305	COG2313	pseudouridylate synthase activity
Vspart_04306	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vspart_04306	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Vspart_04310	COG0546	phosphoglycolate phosphatase activity
Vspart_04317	COG0515	serine threonine protein kinase
Vspart_04324	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Vspart_04325	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
Vspart_04326	COG2204	response regulator
Vspart_04336	COG0516	GMP reductase activity
Vspart_04338	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Vspart_04338	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Vspart_04339	COG3290	protein histidine kinase activity
Vspart_04339	COG3829	transcription factor binding
Vspart_04340	COG2205	protein histidine kinase activity
Vspart_04340	COG3850	Histidine kinase
Vspart_04340	COG4999	Histidine kinase
Vspart_04340	COG3437	response regulator, receiver
Vspart_04342	COG3036	rescue of stalled ribosome
Vspart_04344	COG1278	Cold shock
Vspart_04345	COG3604	Transcriptional regulator
Vspart_04347	COG2195	Cleaves the N-terminal amino acid of tripeptides
Vspart_04349	COG1448	Aminotransferase
Vspart_04352	COG0714	Associated with various cellular activities
Vspart_04359	COG3250	beta-galactosidase activity
Vspart_04360	COG2211	Major facilitator Superfamily
Vspart_04361	COG1522	sequence-specific DNA binding
Vspart_04365	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Vspart_04366	COG0077	Prephenate dehydratase
Vspart_04369	COG1280	lysine exporter protein (LysE YggA)
Vspart_04371	COG4598	ABC transporter
Vspart_04372	COG4160	amino acid transport
Vspart_04373	COG4215	(ABC) transporter
Vspart_04376	COG0840	transmembrane signaling receptor activity
Vspart_04377	COG0840	transmembrane signaling receptor activity
Vspart_04379	COG3118	belongs to the thioredoxin family
Vspart_04380	COG1764	response to oxidative stress
Vspart_04381	COG1846	Transcriptional regulator
Vspart_04383	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
Vspart_04386	COG4104	PAAR repeat-containing protein
Vspart_04388	COG3530	Putative quorum-sensing-regulated virulence factor
Vspart_04389	COG1486	melibiose metabolic process
Vspart_04390	COG0583	DNA-binding transcription factor activity
Vspart_04392	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vspart_04394	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Vspart_04396	COG0784	Response regulator, receiver
Vspart_04396	COG0835	chemotaxis
Vspart_04402	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Vspart_04405	COG0668	transmembrane transport
Vspart_04407	COG1741	Belongs to the pirin family
Vspart_04408	COG0840	transmembrane signaling receptor activity
Vspart_04410	COG0252	asparaginase activity
Vspart_04411	COG0527	aspartate kinase activity
Vspart_04412	COG0662	Cupin 2, conserved barrel domain protein
Vspart_04413	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Vspart_04414	COG0456	acetyltransferase
Vspart_04416	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Vspart_04419	COG0642	Histidine kinase
Vspart_04420	COG0745	RESPONSE REGULATOR receiver
Vspart_04423	COG1022	Amp-dependent synthetase and ligase
Vspart_04427	COG1785	Belongs to the alkaline phosphatase family
Vspart_04430	COG0583	DNA-binding transcription factor activity
Vspart_04434	COG4533	DNA binding
Vspart_04437	COG2211	Major facilitator Superfamily
Vspart_04441	COG1914	H( )-stimulated, divalent metal cation uptake system
Vspart_04442	COG1321	iron dependent repressor
Vspart_04456	COG3501	Rhs element vgr protein
Vspart_04464	COG3501	Rhs element vgr protein
Vspart_04466	COG4191	Histidine kinase
Vspart_04466	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vspart_04467	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vspart_04467	COG4191	Histidine kinase
Vspart_04468	COG0784	Response regulator, receiver
Vspart_04468	COG3437	response regulator, receiver
Vspart_04469	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Vspart_04470	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Vspart_04471	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Vspart_04472	COG3338	carbonate dehydratase activity
Vspart_04475	COG4175	Glycine betaine
Vspart_04476	COG4176	ABC-type proline glycine betaine transport system permease component
Vspart_04477	COG2113	Glycine betaine
Vspart_04478	COG2239	Acts as a magnesium transporter
Vspart_04480	COG0583	DNA-binding transcription factor activity
Vspart_04482	COG0511	ligase activity, forming carbon-carbon bonds
Vspart_04484	COG1984	allophanate hydrolase subunit 2
Vspart_04485	COG2818	Glycosylase
Vspart_04487	COG3300	MHYT domain
Vspart_04487	COG5001	Diguanylate cyclase
Vspart_04488	COG1940	carbohydrate kinase activity
Vspart_04489	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Vspart_04491	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Vspart_04492	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Vspart_04493	COG0534	Mate efflux family protein
Vspart_04494	COG1067	ATP-dependent peptidase activity
Vspart_04496	COG0110	maltose O-acetyltransferase activity
Vspart_04498	COG5520	Belongs to the glycosyl hydrolase 30 family
Vspart_04500	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Vspart_04501	COG0163	prenyltransferase activity
Vspart_04506	COG0277	FAD linked oxidase domain protein
Vspart_04507	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Vspart_04508	COG1640	4-alpha-glucanotransferase
Vspart_04509	COG0058	SHG alpha-glucan phosphorylase activity
Vspart_04510	COG0109	protoheme IX farnesyltransferase activity
Vspart_04511	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Vspart_04512	COG1845	cytochrome c oxidase, subunit III
Vspart_04513	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Vspart_04514	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Vspart_04515	COG0217	transcriptional regulatory protein