locus-tag	class	description
IM698_00015	COG0646	methionine synthase
IM698_00015	COG1410	methionine synthase
IM698_00020	COG0527	aspartate kinase activity
IM698_00025	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IM698_00040	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IM698_00050	COG2197	response regulator
IM698_00055	COG0629	single-stranded DNA binding
IM698_00060	COG2200	EAL domain
IM698_00060	COG2199	diguanylate cyclase activity
IM698_00085	COG3267	Type II secretory pathway component ExeA
IM698_00085	COG3409	Peptidoglycan-binding domain 1 protein
IM698_00095	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IM698_00100	COG1459	type II secretion system
IM698_00110	COG2165	general secretion pathway protein
IM698_00115	COG2165	general secretion pathway protein
IM698_00145	COG1077	Cell shape determining protein MreB Mrl
IM698_00150	COG1792	Involved in formation and maintenance of cell shape
IM698_00155	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IM698_00160	COG0424	maF-like protein
IM698_00175	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IM698_00180	COG0312	modulator of DNA gyrase
IM698_00185	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IM698_00190	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IM698_00205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IM698_00210	COG0589	response to stress
IM698_00225	COG1438	arginine binding
IM698_00230	COG0039	L-malate dehydrogenase activity
IM698_00240	COG0142	geranyltranstransferase activity
IM698_00245	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IM698_00250	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IM698_00255	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IM698_00260	COG2966	Psort location CytoplasmicMembrane, score
IM698_00265	COG3610	response to peptide
IM698_00280	COG2967	ApaG domain
IM698_00285	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IM698_00290	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IM698_00295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IM698_00300	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IM698_00305	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IM698_00320	COG0066	3-isopropylmalate dehydratase activity
IM698_00330	COG0473	3-isopropylmalate dehydrogenase activity
IM698_00335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IM698_00370	COG1022	Amp-dependent synthetase and ligase
IM698_00375	COG0028	Belongs to the TPP enzyme family
IM698_00385	COG3706	GGDEF domain
IM698_00395	COG0469	pyruvate kinase activity
IM698_00400	COG1349	DNA-binding transcription factor activity
IM698_00405	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IM698_00410	COG2873	o-acetylhomoserine
IM698_00470	COG1610	YqeY-like protein
IM698_00475	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IM698_00480	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IM698_00485	COG0596	Alpha beta hydrolase
IM698_00490	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IM698_00495	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IM698_00500	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IM698_00505	COG1968	undecaprenyl-diphosphatase activity
IM698_00510	COG0617	tRNA 3'-terminal CCA addition
IM698_00515	COG3267	Type II secretory pathway component ExeA
IM698_00515	COG3409	Peptidoglycan-binding domain 1 protein
IM698_00525	COG4991	sh3 domain protein
IM698_00530	COG0306	phosphate transporter
IM698_00535	COG1392	Phosphate transport regulator
IM698_00540	COG3025	triphosphatase activity
IM698_00545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IM698_00555	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IM698_00560	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IM698_00560	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IM698_00565	COG1538	Outer membrane efflux protein
IM698_00570	COG0494	nUDIX hydrolase
IM698_00575	COG3151	Protein conserved in bacteria
IM698_00585	COG3150	esterase
IM698_00600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM698_00605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM698_00610	COG3105	Protein conserved in bacteria
IM698_00615	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IM698_00620	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IM698_00625	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IM698_00630	COG0723	plastoquinol--plastocyanin reductase activity
IM698_00635	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IM698_00640	COG2857	Cytochrome c1
IM698_00645	COG0625	glutathione transferase activity
IM698_00650	COG2969	positive regulation of protein catabolic process
IM698_00655	COG2823	Periplasmic or secreted lipoprotein
IM698_00660	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IM698_00675	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IM698_00685	COG0275	rRNA processing
IM698_00690	COG3116	cell division
IM698_00695	COG0768	penicillin binding
IM698_00700	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IM698_00705	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IM698_00710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IM698_00715	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IM698_00720	COG0772	Belongs to the SEDS family
IM698_00725	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IM698_00730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IM698_00735	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IM698_00740	COG0849	cell division
IM698_00745	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IM698_00750	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IM698_00755	COG0653	protein targeting
IM698_00760	COG0494	nUDIX hydrolase
IM698_00765	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IM698_00770	COG0505	Belongs to the CarA family
IM698_00775	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IM698_00780	COG0730	response to heat
IM698_00785	COG0583	DNA-binding transcription factor activity
IM698_00790	COG2860	membrane
IM698_00805	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IM698_00815	COG0493	'glutamate synthase
IM698_00820	COG0067	glutamate synthase
IM698_00820	COG0070	glutamate synthase
IM698_00820	COG0069	glutamate synthase activity
IM698_00830	COG0069	glutamate synthase activity
IM698_00830	COG0070	glutamate synthase
IM698_00830	COG0067	glutamate synthase
IM698_00835	COG1242	4 iron, 4 sulfur cluster binding
IM698_00840	COG2203	Gaf domain
IM698_00840	COG3706	GGDEF domain
IM698_00840	COG4251	negative regulation of phosphorylation
IM698_00840	COG5001	Diguanylate cyclase
IM698_00845	COG5002	protein histidine kinase activity
IM698_00845	COG0784	Response regulator, receiver
IM698_00845	COG2198	Histidine kinase
IM698_00855	COG0745	RESPONSE REGULATOR receiver
IM698_00865	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IM698_00880	COG0083	homoserine kinase activity
IM698_00885	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IM698_00890	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
IM698_00895	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IM698_00900	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IM698_00915	COG1115	amino acid carrier protein
IM698_00920	COG3022	response to hydroperoxide
IM698_00925	COG0513	Belongs to the DEAD box helicase family
IM698_00930	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IM698_00940	COG0716	FMN binding
IM698_00945	COG4974	Belongs to the 'phage' integrase family
IM698_00950	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IM698_00955	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IM698_00970	COG2204	response regulator
IM698_00990	COG0494	nUDIX hydrolase
IM698_01000	COG0730	response to heat
IM698_01005	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IM698_01010	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IM698_01015	COG1283	sodium-dependent phosphate transmembrane transporter activity
IM698_01020	COG0583	DNA-binding transcription factor activity
IM698_01025	COG0640	Transcriptional regulator
IM698_01030	COG0268	Binds directly to 16S ribosomal RNA
IM698_01035	COG0728	peptidoglycan biosynthetic process
IM698_01040	COG0196	riboflavin kinase activity
IM698_01045	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IM698_01055	COG1047	Peptidyl-prolyl cis-trans
IM698_01060	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IM698_01065	COG3279	Response regulator of the LytR AlgR family
IM698_01070	COG3275	phosphorelay sensor kinase activity
IM698_01075	COG3385	transposase activity
IM698_01080	COG1966	Carbon starvation protein
IM698_01090	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IM698_01095	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IM698_01100	COG2971	BadF BadG BcrA BcrD
IM698_01120	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IM698_01125	COG0287	Prephenate dehydrogenase
IM698_01125	COG1605	Chorismate mutase
IM698_01130	COG0739	heme binding
IM698_01140	COG0488	(ABC) transporter
IM698_01150	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
IM698_01155	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
IM698_01160	COG5001	Diguanylate cyclase
IM698_01165	COG0077	Prephenate dehydratase
IM698_01165	COG1605	Chorismate mutase
IM698_01170	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IM698_01175	COG0741	lytic transglycosylase activity
IM698_01180	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IM698_01185	COG0564	pseudouridine synthase activity
IM698_01230	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
IM698_01240	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IM698_01245	COG0826	peptidase U32
IM698_01250	COG2974	May be involved in recombination
IM698_01255	COG0745	RESPONSE REGULATOR receiver
IM698_01260	COG5002	protein histidine kinase activity
IM698_01270	COG0248	Ppx GppA phosphatase
IM698_01275	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IM698_01285	COG0581	inorganic phosphate transmembrane transporter activity
IM698_01290	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IM698_01295	COG0704	Plays a role in the regulation of phosphate uptake
IM698_01310	COG3142	Participates in the control of copper homeostasis
IM698_01315	COG0450	alkyl hydroperoxide reductase
IM698_01320	COG0583	DNA-binding transcription factor activity
IM698_01325	COG0517	IMP dehydrogenase activity
IM698_01330	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IM698_01335	COG0343	queuine tRNA-ribosyltransferase activity
IM698_01340	COG1862	Preprotein translocase
IM698_01345	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IM698_01350	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IM698_01355	COG0483	inositol monophosphate 1-phosphatase activity
IM698_01360	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
IM698_01365	COG1959	2 iron, 2 sulfur cluster binding
IM698_01370	COG1104	cysteine desulfurase activity
IM698_01375	COG0822	iron-sulfur transferase activity
IM698_01385	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IM698_01390	COG0443	Heat shock 70 kDa protein
IM698_01400	COG2975	iron-sulfur cluster assembly
IM698_01405	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IM698_01410	COG0105	UTP biosynthetic process
IM698_01415	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IM698_01425	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IM698_01430	COG0124	histidyl-tRNA synthetase
IM698_01435	COG2976	Protein conserved in bacteria
IM698_01440	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IM698_01445	COG1160	GTP binding
IM698_01455	COG3706	GGDEF domain
IM698_01495	COG0831	urea catabolic process
IM698_01500	COG0832	Belongs to the urease beta subunit family
IM698_01505	COG0804	urea catabolic process
IM698_01510	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
IM698_01525	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IM698_01530	COG1570	exodeoxyribonuclease VII activity
IM698_01535	COG0517	IMP dehydrogenase activity
IM698_01535	COG0516	GMP reductase activity
IM698_01540	COG0519	Catalyzes the synthesis of GMP from XMP
IM698_01540	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IM698_01550	COG1757	Na H antiporter
IM698_01555	COG1584	GPR1 FUN34 yaaH family protein
IM698_01560	COG1115	amino acid carrier protein
IM698_01565	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IM698_01570	COG0204	Acyl-transferase
IM698_01595	COG0189	ligase activity
IM698_01595	COG4067	protein conserved in archaea
IM698_01610	COG2867	negative regulation of translational initiation
IM698_01615	COG2914	Belongs to the UPF0125 (RnfH) family
IM698_01620	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IM698_01625	COG0497	DNA recombination
IM698_01630	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IM698_01635	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IM698_01650	COG0443	Heat shock 70 kDa protein
IM698_01655	COG0484	heat shock protein binding
IM698_01685	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IM698_01690	COG1253	flavin adenine dinucleotide binding
IM698_01705	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IM698_01705	COG0047	phosphoribosylformylglycinamidine synthase activity
IM698_01715	COG2171	N-acyltransferase activity
IM698_01720	COG2095	MarC family integral membrane protein
IM698_01735	COG3141	response to X-ray
IM698_01750	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IM698_01760	COG1074	ATP-dependent DNA helicase activity
IM698_01765	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IM698_01775	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IM698_01775	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IM698_01785	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IM698_01790	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IM698_01795	COG2166	iron-sulfur cluster assembly
IM698_01800	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IM698_01805	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IM698_01810	COG3248	Nucleoside-binding outer membrane protein
IM698_01825	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IM698_01835	COG2813	Specifically methylates the guanine in position
IM698_01840	COG0271	Belongs to the BolA IbaG family
IM698_01845	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IM698_01850	COG1805	sodium ion transport
IM698_01860	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IM698_01865	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IM698_01870	COG2871	sodium ion transport
IM698_01875	COG1477	protein flavinylation
IM698_01880	COG2991	Protein conserved in bacteria
IM698_01890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IM698_01910	COG0733	neurotransmitter:sodium symporter activity
IM698_01915	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IM698_01920	COG0321	lipoyl(octanoyl) transferase activity
IM698_01930	COG1686	Belongs to the peptidase S11 family
IM698_01935	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IM698_01940	COG0772	Belongs to the SEDS family
IM698_01945	COG0768	penicillin binding
IM698_01950	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IM698_01955	COG0799	negative regulation of ribosome biogenesis
IM698_01960	COG1466	dna polymerase III delta subunit
IM698_01965	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
IM698_01970	COG0495	leucyl-tRNA aminoacylation
IM698_01975	COG2888	peptidyl-tyrosine sulfation
IM698_01980	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IM698_01985	COG4535	Mg2 and Co2 transporter CorC
IM698_01990	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IM698_01995	COG1702	phosphate starvation-inducible protein PhoH
IM698_02005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM698_02010	COG2706	6-phosphogluconolactonase activity
IM698_02115	COG0193	aminoacyl-tRNA hydrolase activity
IM698_02120	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IM698_02125	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IM698_02130	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IM698_02135	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IM698_02140	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IM698_02145	COG2890	protein-(glutamine-N5) methyltransferase activity
IM698_02150	COG3094	Invasion gene expression up-regulator, SirB
IM698_02155	COG2912	Transglutaminase-like superfamily
IM698_02160	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IM698_02170	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IM698_02175	COG1187	pseudouridine synthase activity
IM698_02180	COG2840	Smr protein MutS2
IM698_02220	COG2217	Heavy metal translocating P-type atpase
IM698_02220	COG2608	mercury ion transmembrane transporter activity
IM698_02240	COG1028	Short-chain dehydrogenase reductase Sdr
IM698_02280	COG1216	Glycosyl transferase, family 2
IM698_02300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM698_02305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM698_02365	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
IM698_02370	COG0784	Response regulator, receiver
IM698_02370	COG0835	chemotaxis
IM698_02375	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IM698_02380	COG1815	bacterial-type flagellum-dependent cell motility
IM698_02385	COG1558	bacterial-type flagellum-dependent cell motility
IM698_02395	COG1749	Flagellar hook protein flgE
IM698_02400	COG4787	bacterial-type flagellum-dependent cell motility
IM698_02410	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
IM698_02415	COG1706	bacterial-type flagellum-dependent cell motility
IM698_02420	COG1705	Flagellar rod assembly protein muramidase FlgJ
IM698_02420	COG3951	Flagellar rod assembly protein muramidase FlgJ
IM698_02440	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IM698_02445	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IM698_02450	COG1334	flagellar protein FlaG
IM698_02455	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IM698_02465	COG1516	flagellar protein fliS
IM698_02485	COG1677	Flagellar hook-basal body complex protein FliE
IM698_02495	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IM698_02545	COG1987	bacterial-type flagellum assembly
IM698_02550	COG1684	flagellar biosynthetic protein fliR
IM698_02585	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
IM698_02590	COG0784	Response regulator, receiver
IM698_02590	COG0643	Histidine kinase
IM698_02590	COG2198	Histidine kinase
IM698_02595	COG2201	protein-glutamate methylesterase activity
IM698_02600	COG1192	Involved in chromosome partitioning
IM698_02610	COG0835	chemotaxis
IM698_02620	COG4133	protoheme IX ABC transporter activity
IM698_02625	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IM698_02630	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IM698_02635	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IM698_02640	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
IM698_02645	COG1138	Cytochrome C-type biogenesis protein
IM698_02650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IM698_02655	COG4235	cytochrome complex assembly
IM698_02655	COG3088	subunit of a heme lyase
IM698_02660	COG3088	subunit of a heme lyase
IM698_02660	COG4235	cytochrome complex assembly
IM698_02665	COG2853	Lipoprotein
IM698_02695	COG0183	Belongs to the thiolase family
IM698_02700	COG1024	Enoyl-CoA hydratase
IM698_02700	COG1250	3-hydroxyacyl-CoA dehydrogenase
IM698_02710	COG2062	phosphohistidine phosphatase, SixA
IM698_02715	COG2840	Smr protein MutS2
IM698_02720	COG2890	protein-(glutamine-N5) methyltransferase activity
IM698_02725	COG1280	lysine exporter protein (LysE YggA)
IM698_02730	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IM698_02750	COG1175	transmembrane transport
IM698_02760	COG3842	ATPase activity
IM698_02765	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IM698_02770	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IM698_02770	COG2070	2-Nitropropane dioxygenase
IM698_02800	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IM698_02805	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IM698_02810	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IM698_02820	COG2204	response regulator
IM698_02835	COG0544	peptidyl-prolyl cis-trans isomerase activity
IM698_02840	COG0740	serine-type endopeptidase activity
IM698_02845	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IM698_02850	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IM698_02855	COG0776	regulation of translation
IM698_02860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IM698_02865	COG2183	response to ionizing radiation
IM698_02880	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IM698_02885	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
IM698_02890	COG0436	Aminotransferase
IM698_02895	COG1169	isochorismate synthase
IM698_02900	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IM698_02905	COG2267	carboxylic ester hydrolase activity
IM698_02910	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IM698_02930	COG2855	membrane
IM698_02985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM698_02995	COG1454	alcohol dehydrogenase
IM698_03025	COG0641	radical SAM
IM698_03035	COG1309	transcriptional regulator
IM698_03075	COG1902	pentaerythritol trinitrate reductase activity
IM698_03080	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IM698_03085	COG1522	sequence-specific DNA binding
IM698_03095	COG1946	Acyl-CoA thioesterase
IM698_03100	COG3126	Type III secretion system lipoprotein chaperone (YscW)
IM698_03145	COG3655	Transcriptional regulator
IM698_03160	COG3385	transposase activity
IM698_03165	COG4124	Belongs to the glycosyl hydrolase 26 family
IM698_03165	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IM698_03215	COG0328	RNA-DNA hybrid ribonuclease activity
IM698_03215	COG3341	Caulimovirus viroplasmin
IM698_03220	COG0438	transferase activity, transferring glycosyl groups
IM698_03225	COG0463	Glycosyl transferase, family 2
IM698_03225	COG1216	Glycosyl transferase, family 2
IM698_03260	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IM698_03275	COG0789	Transcriptional regulator
IM698_03280	COG3394	polysaccharide catabolic process
IM698_03290	COG0583	DNA-binding transcription factor activity
IM698_03315	COG3119	arylsulfatase activity
IM698_03320	COG1609	Transcriptional regulator
IM698_03345	COG1760	l-serine dehydratase
IM698_03350	COG1522	sequence-specific DNA binding
IM698_03355	COG1280	lysine exporter protein (LysE YggA)
IM698_03380	COG2207	Transcriptional regulator
IM698_03380	COG3708	Transcriptional regulator
IM698_03390	COG2233	PERMEase
IM698_03395	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IM698_03400	COG1227	inorganic diphosphatase activity
IM698_03405	COG0494	nUDIX hydrolase
IM698_03410	COG3153	acetyltransferase
IM698_03455	COG0446	pyridine nucleotide-disulphide oxidoreductase
IM698_03465	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IM698_03480	COG1228	amidohydrolase
IM698_03495	COG3040	lipid binding
IM698_03500	COG1309	transcriptional regulator
IM698_03515	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IM698_03520	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IM698_03525	COG1845	cytochrome c oxidase, subunit III
IM698_03530	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IM698_03545	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IM698_03570	COG0583	DNA-binding transcription factor activity
IM698_03575	COG0346	lactoylglutathione lyase activity
IM698_03580	COG1902	pentaerythritol trinitrate reductase activity
IM698_03610	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IM698_03635	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IM698_03635	COG0617	tRNA 3'-terminal CCA addition
IM698_03635	COG0517	IMP dehydrogenase activity
IM698_03665	COG0537	adenosine 5'-monophosphoramidase activity
IM698_03690	COG3150	esterase
IM698_03695	COG1252	NADH dehydrogenase
IM698_03710	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IM698_03720	COG4591	ABC-type transport system involved in lipoprotein release permease component
IM698_03725	COG1136	(ABC) transporter
IM698_03730	COG4591	ABC-type transport system involved in lipoprotein release permease component
IM698_03740	COG2333	competence protein COMEC
IM698_03740	COG0658	competence protein
IM698_03745	COG1132	(ABC) transporter
IM698_03750	COG1663	tetraacyldisaccharide 4'-kinase activity
IM698_03755	COG2835	tetraacyldisaccharide 4'-kinase activity
IM698_03760	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IM698_03765	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IM698_03770	COG0539	negative regulation of cytoplasmic translation
IM698_03775	COG0776	regulation of translation
IM698_03780	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
IM698_03785	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IM698_03790	COG0284	orotidine-5'-phosphate decarboxylase activity
IM698_03805	COG0583	DNA-binding transcription factor activity
IM698_03815	COG0686	Belongs to the AlaDH PNT family
IM698_03820	COG1522	sequence-specific DNA binding
IM698_03825	COG1674	ftsk spoiiie
IM698_03830	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IM698_03835	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IM698_03840	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IM698_03845	COG0745	RESPONSE REGULATOR receiver
IM698_03855	COG2205	protein histidine kinase activity
IM698_03855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM698_03860	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IM698_03865	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IM698_03870	COG0156	8-amino-7-oxononanoate synthase activity
IM698_03875	COG2226	methyltransferase
IM698_03880	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IM698_03890	COG0501	Belongs to the peptidase M48B family
IM698_03895	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IM698_03900	COG2915	High frequency lysogenization protein hflD homolog
IM698_03915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM698_03920	COG2916	Histone family protein nucleoid-structuring protein H-NS
IM698_03925	COG1757	Na H antiporter
IM698_03940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IM698_03945	COG0131	Imidazoleglycerol-phosphate dehydratase
IM698_03945	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IM698_03950	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IM698_03955	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IM698_03960	COG0107	imidazoleglycerol-phosphate synthase activity
IM698_03965	COG0140	phosphoribosyl-ATP diphosphatase activity
IM698_03965	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IM698_03970	COG3012	SEC-C Motif Domain Protein
IM698_03975	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IM698_03980	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IM698_03985	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IM698_03990	COG0215	cysteine-tRNA ligase activity
IM698_04020	COG2116	formate transmembrane transporter activity
IM698_04025	COG0390	transport system, permease component
IM698_04030	COG4459	periplasmic nitrate reductase
IM698_04035	COG3005	denitrification pathway
IM698_04040	COG0243	molybdopterin cofactor binding
IM698_04050	COG1227	inorganic diphosphatase activity
IM698_04065	COG4172	Belongs to the ABC transporter superfamily
IM698_04080	COG4168	peptide transport system, permease
IM698_04085	COG4166	transmembrane transport
IM698_04090	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IM698_04095	COG1842	Phage shock protein A
IM698_04105	COG1983	PspC domain protein
IM698_04110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM698_04125	COG2818	Glycosylase
IM698_04140	COG0626	cystathionine gamma-synthase activity
IM698_04150	COG0733	neurotransmitter:sodium symporter activity
IM698_04160	COG0564	pseudouridine synthase activity
IM698_04165	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IM698_04165	COG0116	Belongs to the methyltransferase superfamily
IM698_04170	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IM698_04175	COG4136	ATPase activity
IM698_04180	COG4135	transport system, permease component
IM698_04185	COG4134	Bacterial extracellular solute-binding protein
IM698_04195	COG3313	Fe-S protein
IM698_04215	COG0513	Belongs to the DEAD box helicase family
IM698_04220	COG1280	lysine exporter protein (LysE YggA)
IM698_04230	COG2866	Carboxypeptidase
IM698_04240	COG3005	denitrification pathway
IM698_04245	COG0243	molybdopterin cofactor binding
IM698_04265	COG4176	ABC-type proline glycine betaine transport system permease component
IM698_04270	COG2113	Glycine betaine
IM698_04280	COG0583	DNA-binding transcription factor activity
IM698_04285	COG2995	paraquat-inducible protein a
IM698_04290	COG3008	intermembrane lipid transfer
IM698_04290	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IM698_04325	COG2165	general secretion pathway protein
IM698_04340	COG4796	Type ii and iii secretion system protein
IM698_04360	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IM698_04365	COG1459	type II secretion system
IM698_04420	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IM698_04430	COG0586	Pfam SNARE associated Golgi protein
IM698_04440	COG0642	Histidine kinase
IM698_04455	COG1061	Type III restriction enzyme res subunit
IM698_04465	COG2814	Major facilitator Superfamily
IM698_04475	COG0702	epimerase
IM698_04480	COG0534	Mate efflux family protein
IM698_04500	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IM698_04505	COG3047	cAMP biosynthetic process
IM698_04505	COG2885	chlorophyll binding
IM698_04530	COG3385	transposase activity
IM698_04535	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IM698_04540	COG2985	domain, Protein
IM698_04540	COG3273	potassium ion transport
IM698_04545	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IM698_04555	COG1737	Transcriptional regulator
IM698_04560	COG0076	glutamate decarboxylase activity
IM698_04570	COG2431	L-lysine efflux transmembrane transporter activity
IM698_04580	COG3070	regulator of competence-specific genes
IM698_04590	COG2204	response regulator
IM698_04595	COG3852	Histidine kinase
IM698_04605	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IM698_04620	COG2258	MOSC domain
IM698_04625	COG2176	DNA-directed DNA polymerase activity
IM698_04640	COG1448	Aminotransferase
IM698_04645	COG2770	Histidine kinase
IM698_04645	COG3437	response regulator, receiver
IM698_04655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM698_04665	COG0017	Asparaginyl-tRNA synthetase
IM698_04670	COG0659	secondary active sulfate transmembrane transporter activity
IM698_04675	COG0840	transmembrane signaling receptor activity
IM698_04685	COG0814	amino acid
IM698_04690	COG1760	l-serine dehydratase
IM698_04695	COG0814	amino acid
IM698_04700	COG0494	nUDIX hydrolase
IM698_04710	COG0784	Response regulator, receiver
IM698_04710	COG5002	protein histidine kinase activity
IM698_04715	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IM698_04730	COG3106	COG3106 Predicted ATPase
IM698_04745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM698_04760	COG0443	Heat shock 70 kDa protein
IM698_04775	COG3706	GGDEF domain
IM698_04795	COG3710	Transcriptional regulator
IM698_04825	COG1643	Atp-dependent helicase
IM698_04865	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IM698_04870	COG0072	phenylalanine-tRNA ligase activity
IM698_04870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM698_04875	COG1196	nuclear chromosome segregation
IM698_04930	COG0302	gtp cyclohydrolase
IM698_04935	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IM698_04940	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IM698_04955	COG1464	Belongs to the NlpA lipoprotein family
IM698_04965	COG1522	sequence-specific DNA binding
IM698_05015	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
IM698_05040	COG0776	regulation of translation
IM698_05060	COG0840	transmembrane signaling receptor activity
IM698_05070	COG0583	DNA-binding transcription factor activity
IM698_05080	COG2175	clavaminate synthase activity
IM698_05095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM698_05105	COG2988	succinylglutamate desuccinylase activity
IM698_05110	COG0523	cobalamin synthesis protein
IM698_05120	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IM698_05130	COG0776	regulation of translation
IM698_05140	COG0500	methyltransferase
IM698_05150	COG0295	cytidine deaminase activity
IM698_05155	COG1346	cytolysis
IM698_05165	COG2925	Exonuclease
IM698_05210	COG3568	Endonuclease Exonuclease Phosphatase
IM698_05215	COG3122	Protein conserved in bacteria
IM698_05230	COG4989	oxidoreductase activity
IM698_05240	COG1823	symporter activity
IM698_05245	COG0702	epimerase
IM698_05250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IM698_05255	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IM698_05260	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IM698_05280	COG2988	succinylglutamate desuccinylase activity
IM698_05285	COG4139	cobalamin transport
IM698_05290	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
IM698_05300	COG0747	negative chemotaxis
IM698_05305	COG0601	transmembrane transport
IM698_05310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM698_05330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM698_05335	COG1271	oxidase subunit
IM698_05340	COG1294	oxidase, subunit
IM698_05350	COG1247	-acetyltransferase
IM698_05370	COG2814	Major facilitator Superfamily
IM698_05375	COG0583	DNA-binding transcription factor activity
IM698_05385	COG1451	nucleotide metabolic process
IM698_05395	COG3063	Type IV pilus biogenesis stability protein PilW
IM698_05400	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IM698_05415	COG2195	Cleaves the N-terminal amino acid of tripeptides
IM698_05420	COG3706	GGDEF domain
IM698_05485	COG1401	restriction endodeoxyribonuclease activity
IM698_05495	COG1196	nuclear chromosome segregation
IM698_05510	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IM698_05525	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IM698_05630	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IM698_05645	COG0840	transmembrane signaling receptor activity
IM698_05660	COG3469	chitinase activity
IM698_05670	COG4771	TonB-dependent receptor
IM698_05680	COG2199	diguanylate cyclase activity
IM698_05685	COG0454	-acetyltransferase
IM698_05700	COG0420	3'-5' exonuclease activity
IM698_05705	COG0419	ATPase involved in DNA repair
IM698_05725	COG3046	protein related to deoxyribodipyrimidine photolyase
IM698_05730	COG0415	Belongs to the DNA photolyase family
IM698_05735	COG0589	response to stress
IM698_05755	COG1120	ATPase activity
IM698_05760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IM698_05765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM698_05770	COG4615	Cyclic peptide transporter
IM698_05790	COG4774	siderophore transport
IM698_05810	COG2271	Major facilitator Superfamily
IM698_05820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IM698_05840	COG0494	nUDIX hydrolase
IM698_05855	COG1187	pseudouridine synthase activity
IM698_05865	COG0110	maltose O-acetyltransferase activity
IM698_05875	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IM698_05890	COG0494	nUDIX hydrolase
IM698_05920	COG0346	lactoylglutathione lyase activity
IM698_05940	COG1619	proteins homologs of microcin C7 resistance protein MccF
IM698_05960	COG0653	protein targeting
IM698_05970	COG1028	Short-chain dehydrogenase reductase Sdr
IM698_06005	COG0786	glutamate:sodium symporter activity
IM698_06020	COG0826	peptidase U32
IM698_06025	COG3385	transposase activity
IM698_06040	COG1126	abc transporter atp-binding protein
IM698_06045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM698_06050	COG4215	(ABC) transporter
IM698_06055	COG4160	amino acid transport
IM698_06085	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IM698_06115	COG1742	UPF0060 membrane protein
IM698_06140	COG0583	DNA-binding transcription factor activity
IM698_06175	COG0741	lytic transglycosylase activity
IM698_06180	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
IM698_06195	COG2066	Belongs to the glutaminase family
IM698_06205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IM698_06210	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IM698_06225	COG0762	integral membrane protein
IM698_06230	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IM698_06235	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IM698_06250	COG3385	transposase activity
IM698_06260	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IM698_06265	COG1678	Uncharacterized ACR, COG1678
IM698_06270	COG0189	ligase activity
IM698_06275	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IM698_06280	COG2356	endonuclease I
IM698_06285	COG3091	SprT-like family
IM698_06295	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IM698_06300	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IM698_06315	COG0191	fructose-bisphosphate aldolase activity
IM698_06320	COG0668	transmembrane transport
IM698_06325	COG1279	arginine transmembrane transporter activity
IM698_06340	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IM698_06345	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IM698_06350	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IM698_06360	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IM698_06365	COG3079	Belongs to the UPF0149 family
IM698_06370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM698_06375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM698_06390	COG0354	folic acid binding
IM698_06395	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IM698_06405	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IM698_06410	COG1595	DNA-templated transcription, initiation
IM698_06430	COG0481	GTPase activity
IM698_06440	COG0571	ribonuclease III activity
IM698_06445	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IM698_06450	COG1381	Involved in DNA repair and RecF pathway recombination
IM698_06455	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IM698_06460	COG0736	holo-[acyl-carrier-protein] synthase activity
IM698_06465	COG3437	response regulator, receiver
IM698_06465	COG3850	Histidine kinase
IM698_06465	COG4999	Histidine kinase
IM698_06465	COG2205	protein histidine kinase activity
IM698_06470	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IM698_06475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IM698_06480	COG3956	TIGRFAM MazG family protein
IM698_06485	COG0504	CTP synthase activity
IM698_06490	COG0148	phosphopyruvate hydratase activity
IM698_06495	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IM698_06500	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IM698_06510	COG0585	pseudouridine synthase activity
IM698_06515	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IM698_06520	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IM698_06530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IM698_06535	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IM698_06540	COG1546	Belongs to the CinA family
IM698_06545	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IM698_06555	COG0527	aspartate kinase activity
IM698_06615	COG3630	sodium ion export across plasma membrane
IM698_06620	COG0511	ligase activity, forming carbon-carbon bonds
IM698_06620	COG5016	pyruvate
IM698_06625	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
IM698_06635	COG1238	metal cluster binding
IM698_06640	COG0612	Peptidase, M16
IM698_06645	COG2918	glutathione biosynthetic process
IM698_06655	COG1854	S-ribosylhomocysteine lyase activity
IM698_06660	COG4536	flavin adenine dinucleotide binding
IM698_06665	COG4137	Cytochrome C assembly protein
IM698_06670	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IM698_06675	COG0228	four-way junction DNA binding
IM698_06680	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IM698_06685	COG0336	Belongs to the RNA methyltransferase TrmD family
IM698_06690	COG0335	large ribosomal subunit rRNA binding
IM698_06700	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
IM698_06705	COG0237	dephospho-CoA kinase activity
IM698_06715	COG1459	type II secretion system
IM698_06720	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IM698_06730	COG0157	Belongs to the NadC ModD family
IM698_06740	COG2186	Transcriptional regulator
IM698_06745	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IM698_06750	COG0508	dehydrogenase complex catalyzes the overall conversion of
IM698_06755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IM698_06775	COG0288	reversible hydration of carbon dioxide
IM698_06780	COG0659	secondary active sulfate transmembrane transporter activity
IM698_06785	COG1131	(ABC) transporter
IM698_06790	COG0842	Transport permease protein
IM698_06795	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IM698_06800	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IM698_06805	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IM698_06825	COG1489	DNA binding
IM698_06830	COG1643	Atp-dependent helicase
IM698_06835	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IM698_06840	COG1752	Esterase of the alpha-beta hydrolase superfamily
IM698_06845	COG1049	propionate catabolic process, 2-methylcitrate cycle
IM698_06860	COG0004	ammonium transporteR
IM698_06865	COG1840	ABC-type Fe3 transport system, periplasmic component
IM698_06875	COG3842	ATPase activity
IM698_06880	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IM698_06895	COG2971	BadF BadG BcrA BcrD
IM698_06905	COG4608	Belongs to the ABC transporter superfamily
IM698_06910	COG0444	Belongs to the ABC transporter superfamily
IM698_06915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM698_06925	COG0747	negative chemotaxis
IM698_06935	COG2813	Specifically methylates the guanine in position
IM698_06940	COG0628	permease
IM698_06945	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IM698_06950	COG0316	Belongs to the HesB IscA family
IM698_06965	COG0739	heme binding
IM698_06970	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IM698_06975	COG2239	Acts as a magnesium transporter
IM698_06980	COG2027	D-alanyl-D-alanine carboxypeptidase
IM698_06985	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IM698_06990	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IM698_06995	COG1534	Rna-binding protein
IM698_07000	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IM698_07005	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IM698_07010	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IM698_07015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IM698_07020	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IM698_07035	COG0779	Required for maturation of 30S ribosomal subunits
IM698_07040	COG0195	Participates in both transcription termination and antitermination
IM698_07045	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IM698_07050	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IM698_07055	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IM698_07060	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IM698_07065	COG1185	polyribonucleotide nucleotidyltransferase activity
IM698_07080	COG0534	Mate efflux family protein
IM698_07085	COG0826	peptidase U32
IM698_07090	COG0826	peptidase U32
IM698_07100	COG3154	lipid carrier protein
IM698_07105	COG3153	acetyltransferase
IM698_07120	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IM698_07145	COG0084	hydrolase, TatD family'
IM698_07150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IM698_07155	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IM698_07160	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IM698_07170	COG0813	purine-nucleoside phosphorylase activity
IM698_07180	COG0560	Phosphoserine phosphatase
IM698_07190	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IM698_07195	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IM698_07225	COG4628	conserved protein (DUF2132)
IM698_07230	COG0583	DNA-binding transcription factor activity
IM698_07240	COG1022	Amp-dependent synthetase and ligase
IM698_07255	COG0583	DNA-binding transcription factor activity
IM698_07275	COG4964	Belongs to the GSP D family
IM698_07285	COG0455	bacterial-type flagellum organization
IM698_07330	COG2059	Chromate
IM698_07335	COG0583	DNA-binding transcription factor activity
IM698_07340	COG1609	Transcriptional regulator
IM698_07350	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM698_07355	COG0534	Mate efflux family protein
IM698_07365	COG1175	transmembrane transport
IM698_07370	COG0395	ABC-type sugar transport system, permease component
IM698_07380	COG3250	beta-galactosidase activity
IM698_07385	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
IM698_07385	COG3408	Glycogen debranching enzyme
IM698_07395	COG0531	amino acid
IM698_07400	COG0531	amino acid
IM698_07405	COG2731	YhcH YjgK YiaL family protein
IM698_07410	COG3250	beta-galactosidase activity
IM698_07415	COG1609	Transcriptional regulator
IM698_07420	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IM698_07425	COG1085	galactose-1-phosphate uridylyltransferase
IM698_07435	COG2017	converts alpha-aldose to the beta-anomer
IM698_07440	COG1609	Transcriptional regulator
IM698_07445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM698_07460	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IM698_07480	COG2195	Cleaves the N-terminal amino acid of tripeptides
IM698_07485	COG2252	PERMEase
IM698_07490	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
IM698_07495	COG1073	alpha beta
IM698_07505	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IM698_07510	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IM698_07515	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IM698_07520	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IM698_07520	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IM698_07540	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IM698_07545	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IM698_07550	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IM698_07555	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IM698_07560	COG0142	geranyltranstransferase activity
IM698_07565	COG1722	exodeoxyribonuclease VII activity
IM698_07570	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IM698_07580	COG0301	tRNA thio-modification
IM698_07580	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM698_07585	COG0583	DNA-binding transcription factor activity
IM698_07600	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
IM698_07605	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IM698_07610	COG1611	Belongs to the LOG family
IM698_07625	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IM698_07625	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IM698_07635	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
IM698_07640	COG4580	involved in the transport of maltose and maltodextrins
IM698_07645	COG1464	Belongs to the NlpA lipoprotein family
IM698_07650	COG2011	ABC-type metal ion transport system permease component
IM698_07655	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IM698_07660	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IM698_07670	COG1609	Transcriptional regulator
IM698_07675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM698_07675	COG1263	PTS System
IM698_07680	COG0366	Alpha amylase catalytic
IM698_07705	COG3385	transposase activity
IM698_07725	COG0442	prolyl-tRNA aminoacylation
IM698_07730	COG1720	tRNA m6t6A37 methyltransferase activity
IM698_07735	COG0254	rRNA binding
IM698_07745	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IM698_07755	COG1671	Belongs to the UPF0178 family
IM698_07780	COG3098	single-species biofilm formation
IM698_07785	COG0564	pseudouridine synthase activity
IM698_07795	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IM698_07800	COG0024	Methionine aminopeptidase
IM698_07805	COG0052	Belongs to the universal ribosomal protein uS2 family
IM698_07810	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IM698_07815	COG0528	UMP kinase activity
IM698_07820	COG0233	cytoplasmic translational termination
IM698_07825	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IM698_07830	COG0575	Belongs to the CDS family
IM698_07840	COG0750	zinc metalloprotease
IM698_07850	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
IM698_07855	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IM698_07860	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IM698_07865	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IM698_07875	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IM698_07880	COG0587	DNA-directed DNA polymerase activity
IM698_07885	COG0825	malonyl-CoA metabolic process
IM698_07890	COG0037	tRNA processing
IM698_07900	COG0347	Belongs to the P(II) protein family
IM698_07905	COG3021	interspecies interaction between organisms
IM698_07915	COG1388	LysM domain
IM698_07915	COG0741	lytic transglycosylase activity
IM698_07920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM698_07925	COG2226	methyltransferase
IM698_07930	COG0328	RNA-DNA hybrid ribonuclease activity
IM698_07935	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IM698_07945	COG1960	acyl-CoA dehydrogenase activity
IM698_07950	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IM698_07955	COG0121	glutamine amidotransferase
IM698_07960	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IM698_07965	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IM698_07975	COG2233	PERMEase
IM698_07995	COG1393	Belongs to the ArsC family
IM698_08000	COG4783	chaperone-mediated protein folding
IM698_08015	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IM698_08020	COG2716	regulation of RNA biosynthetic process
IM698_08025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM698_08030	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
IM698_08045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IM698_08050	COG1393	Belongs to the ArsC family
IM698_08075	COG2837	iron assimilation
IM698_08080	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IM698_08085	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IM698_08090	COG2190	(PTS) system
IM698_08100	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM698_08110	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
IM698_08115	COG3115	cell septum assembly
IM698_08120	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IM698_08135	COG0789	Transcriptional regulator
IM698_08145	COG0330	HflC and HflK could
IM698_08150	COG3118	belongs to the thioredoxin family
IM698_08155	COG0300	oxidoreductase activity
IM698_08160	COG1090	epimerase
IM698_08185	COG0622	Phosphoesterase
IM698_08200	COG3710	Transcriptional regulator
IM698_08205	COG0326	Molecular chaperone. Has ATPase activity
IM698_08210	COG0563	adenylate kinase activity
IM698_08215	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IM698_08220	COG3104	oligopeptide transport
IM698_08230	COG0367	asparagine synthase
IM698_08235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IM698_08235	COG4651	solute:proton antiporter activity
IM698_08240	COG1846	Transcriptional regulator
IM698_08240	COG1940	carbohydrate kinase activity
IM698_08245	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IM698_08250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM698_08250	COG1263	PTS System
IM698_08250	COG2190	(PTS) system
IM698_08255	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IM698_08280	COG0596	Alpha beta hydrolase
IM698_08285	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
IM698_08290	COG0033	Phosphoglucomutase
IM698_08300	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IM698_08315	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IM698_08320	COG1053	succinate dehydrogenase
IM698_08325	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IM698_08330	COG0567	Dehydrogenase, E1 component
IM698_08335	COG0508	dehydrogenase complex catalyzes the overall conversion of
IM698_08340	COG0045	succinate-CoA ligase (ADP-forming) activity
IM698_08350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IM698_08355	COG1121	(ABC) transporter
IM698_08360	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
IM698_08370	COG1918	ferrous iron import across plasma membrane
IM698_08390	COG0018	arginyl-trna synthetase
IM698_08395	COG3102	Protein conserved in bacteria
IM698_08400	COG0788	formyltetrahydrofolate deformylase activity
IM698_08410	COG1199	ATP-dependent helicase activity
IM698_08415	COG1214	PFAM Peptidase M22, glycoprotease
IM698_08430	COG0596	Alpha beta hydrolase
IM698_08435	COG0318	PFAM AMP-dependent synthetase and ligase
IM698_08440	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IM698_08445	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IM698_08450	COG2894	cell division
IM698_08455	COG0850	regulation of cytokinetic process
IM698_08460	COG3100	YcgL domain-containing protein
IM698_08465	COG2951	lytic endotransglycosylase activity
IM698_08470	COG0583	DNA-binding transcription factor activity
IM698_08475	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IM698_08490	COG2963	transposase activity
IM698_08495	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IM698_08505	COG2815	serine threonine protein kinase
IM698_08505	COG0515	serine threonine protein kinase
IM698_08520	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IM698_08530	COG2860	membrane
IM698_08535	COG3101	peptidyl-lysine hydroxylation
IM698_08555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IM698_08560	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IM698_08565	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IM698_08575	COG0101	tRNA pseudouridine synthase activity
IM698_08580	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IM698_08585	COG0285	dihydrofolate synthase activity
IM698_08590	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
IM698_08595	COG1286	toxin biosynthetic process
IM698_08600	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IM698_08605	COG0583	DNA-binding transcription factor activity
IM698_08610	COG0745	RESPONSE REGULATOR receiver
IM698_08620	COG2832	Protein of unknown function (DUF454)
IM698_08625	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IM698_08630	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IM698_08635	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IM698_08640	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IM698_08655	COG2983	Belongs to the UPF0260 family
IM698_08675	COG2226	methyltransferase
IM698_08690	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IM698_08695	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IM698_08705	COG3139	Protein of unknown function (DUF1315)
IM698_08710	COG0252	asparaginase activity
IM698_08715	COG0616	signal peptide processing
IM698_08720	COG0446	pyridine nucleotide-disulphide oxidoreductase
IM698_08720	COG1902	pentaerythritol trinitrate reductase activity
IM698_08725	COG0778	Nitroreductase
IM698_08730	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IM698_08745	COG0123	including yeast histone deacetylase and acetoin utilization protein
IM698_08840	COG2205	protein histidine kinase activity
IM698_08850	COG2801	Transposase and inactivated derivatives
IM698_08890	COG0582	viral genome integration into host DNA
IM698_08925	COG3082	Protein of unknown function (DUF1414)
IM698_08930	COG3081	Nucleoid-associated protein
IM698_08945	COG1757	Na H antiporter
IM698_08950	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IM698_08955	COG2165	general secretion pathway protein
IM698_08960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IM698_08965	COG2095	MarC family integral membrane protein
IM698_08970	COG1454	alcohol dehydrogenase
IM698_08970	COG1012	belongs to the aldehyde dehydrogenase family
IM698_08990	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IM698_09000	COG2056	Na+-H+ antiporter family
IM698_09005	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IM698_09020	COG0346	lactoylglutathione lyase activity
IM698_09025	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IM698_09030	COG4660	Part of a membrane complex involved in electron transport
IM698_09035	COG4659	FMN binding
IM698_09040	COG4658	electron transport chain
IM698_09045	COG4656	Part of a membrane complex involved in electron transport
IM698_09050	COG2878	Part of a membrane complex involved in electron transport
IM698_09055	COG4657	Part of a membrane complex involved in electron transport
IM698_09060	COG1609	Transcriptional regulator
IM698_09065	COG3250	beta-galactosidase activity
IM698_09075	COG4580	involved in the transport of maltose and maltodextrins
IM698_09085	COG2211	Major facilitator Superfamily
IM698_09095	COG0556	nucleotide-excision repair
IM698_09100	COG2204	response regulator
IM698_09105	COG2198	Histidine kinase
IM698_09110	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IM698_09115	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IM698_09120	COG0521	Mo-molybdopterin cofactor biosynthetic process
IM698_09125	COG0315	cyclic pyranopterin monophosphate synthase activity
IM698_09130	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IM698_09135	COG0314	molybdopterin synthase activity
IM698_09145	COG0601	transmembrane transport
IM698_09150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM698_09155	COG0444	Belongs to the ABC transporter superfamily
IM698_09165	COG0435	Glutathione S-transferase
IM698_09170	COG0280	phosphate acetyltransferase
IM698_09170	COG0857	belongs to the CobB CobQ family
IM698_09175	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IM698_09180	COG3092	negative regulation of chromosome organization
IM698_09190	COG3706	GGDEF domain
IM698_09195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IM698_09200	COG0653	protein targeting
IM698_09205	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IM698_09210	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IM698_09215	COG2186	Transcriptional regulator
IM698_09225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM698_09225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM698_09230	COG0489	protein tyrosine kinase activity
IM698_09235	COG0572	uridine kinase
IM698_09240	COG2982	Protein involved in outer membrane biogenesis
IM698_09245	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
IM698_09250	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IM698_09255	COG0659	secondary active sulfate transmembrane transporter activity
IM698_09260	COG1530	ribonuclease E activity
IM698_09265	COG0564	pseudouridine synthase activity
IM698_09275	COG1399	metal-binding, possibly nucleic acid-binding protein
IM698_09280	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IM698_09285	COG0416	fatty acid biosynthetic process
IM698_09290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IM698_09315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IM698_09320	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IM698_09335	COG0084	hydrolase, TatD family'
IM698_09360	COG4667	esterase of the alpha-beta hydrolase superfamily
IM698_09365	COG0469	pyruvate kinase activity
IM698_09370	COG1940	carbohydrate kinase activity
IM698_09375	COG0835	chemotaxis
IM698_09375	COG0784	Response regulator, receiver
IM698_09390	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IM698_09395	COG1028	Short-chain dehydrogenase reductase Sdr
IM698_09400	COG0616	signal peptide processing
IM698_09405	COG2719	SpoVR family
IM698_09410	COG2718	Belongs to the UPF0229 family
IM698_09415	COG2766	serine protein kinase
IM698_09425	COG3013	Belongs to the UPF0304 family
IM698_09430	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IM698_09440	COG1882	Formate acetyltransferase
IM698_09470	COG4160	amino acid transport
IM698_09480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM698_09490	COG0708	Exodeoxyribonuclease III
IM698_09495	COG1770	oligopeptidase
IM698_09500	COG2814	Major facilitator Superfamily
IM698_09505	COG0840	transmembrane signaling receptor activity
IM698_09510	COG2850	peptidyl-arginine hydroxylation
IM698_09530	COG1199	ATP-dependent helicase activity
IM698_09540	COG1187	pseudouridine synthase activity
IM698_09550	COG1278	Cold shock
IM698_09555	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IM698_09560	COG0542	response to heat
IM698_09565	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IM698_09570	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
IM698_09575	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IM698_09585	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IM698_09595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IM698_09600	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IM698_09605	COG0297	glycogen (starch) synthase activity
IM698_09625	COG3070	regulator of competence-specific genes
IM698_09630	COG1609	Transcriptional regulator
IM698_09635	COG3381	protein complex oligomerization
IM698_09640	COG0745	RESPONSE REGULATOR receiver
IM698_09645	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IM698_09650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IM698_09655	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
IM698_09660	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
IM698_09665	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
IM698_09670	COG3385	transposase activity
IM698_09675	COG3383	formate dehydrogenase (NAD+) activity
IM698_09690	COG0189	ligase activity
IM698_09690	COG4067	protein conserved in archaea
IM698_09695	COG0500	methyltransferase
IM698_09700	COG4106	trans-aconitate 2-methyltransferase activity
IM698_09705	COG1801	Protein of unknown function DUF72
IM698_09710	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IM698_09715	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IM698_09725	COG0632	four-way junction helicase activity
IM698_09730	COG2255	four-way junction helicase activity
IM698_09735	COG1271	oxidase subunit
IM698_09740	COG1294	oxidase, subunit
IM698_09745	COG4890	Cyd operon protein YbgT
IM698_09755	COG0824	Thioesterase
IM698_09760	COG0811	peptide transport
IM698_09775	COG0823	Involved in the tonB-independent uptake of proteins
IM698_09780	COG2885	chlorophyll binding
IM698_09785	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
IM698_09790	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IM698_09805	COG0784	Response regulator, receiver
IM698_09805	COG5002	protein histidine kinase activity
IM698_09820	COG0786	glutamate:sodium symporter activity
IM698_09825	COG1349	DNA-binding transcription factor activity
IM698_09845	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IM698_09855	COG0583	DNA-binding transcription factor activity
IM698_09860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM698_09880	COG0745	RESPONSE REGULATOR receiver
IM698_09885	COG0463	Glycosyl transferase, family 2
IM698_09900	COG3135	benzoate transporter
IM698_09905	COG1396	sequence-specific DNA binding
IM698_09910	COG1032	radical SAM domain protein
IM698_09925	COG0583	DNA-binding transcription factor activity
IM698_09930	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IM698_09940	COG2350	Protein conserved in bacteria
IM698_09945	COG1607	acyl-coa hydrolase
IM698_09950	COG2917	probably involved in intracellular septation
IM698_09960	COG0583	DNA-binding transcription factor activity
IM698_09970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM698_09980	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IM698_09990	COG1301	dicarboxylic acid transport
IM698_09995	COG0159	tryptophan synthase activity
IM698_10000	COG0133	tryptophan synthase activity
IM698_10005	COG0135	phosphoribosylanthranilate isomerase activity
IM698_10005	COG0134	indole-3-glycerol-phosphate synthase activity
IM698_10010	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IM698_10015	COG0512	Glutamine amidotransferase of anthranilate synthase
IM698_10020	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IM698_10030	COG0613	PHP domain protein
IM698_10035	COG0009	L-threonylcarbamoyladenylate synthase
IM698_10040	COG1187	pseudouridine synthase activity
IM698_10055	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IM698_10065	COG0417	DNA replication proofreading
IM698_10070	COG2197	response regulator
IM698_10075	COG0322	excinuclease ABC activity
IM698_10115	COG0019	diaminopimelate decarboxylase activity
IM698_10135	COG3302	dmso reductase anchor subunit
IM698_10140	COG0437	4 iron, 4 sulfur cluster binding
IM698_10145	COG0243	molybdopterin cofactor binding
IM698_10150	COG3381	protein complex oligomerization
IM698_10165	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IM698_10170	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IM698_10175	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IM698_10195	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
IM698_10205	COG0437	4 iron, 4 sulfur cluster binding
IM698_10210	COG3301	Polysulphide reductase, NrfD
IM698_10215	COG1138	Cytochrome C-type biogenesis protein
IM698_10225	COG4235	cytochrome complex assembly
IM698_10225	COG3088	subunit of a heme lyase
IM698_10235	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IM698_10260	COG2989	Protein conserved in bacteria
IM698_10265	COG3108	Peptidase M15
IM698_10270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM698_10285	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IM698_10310	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IM698_10315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IM698_10320	COG0840	transmembrane signaling receptor activity
IM698_10325	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IM698_10330	COG4988	ABC transporter
IM698_10335	COG0492	ferredoxin-NADP+ reductase activity
IM698_10355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IM698_10370	COG2199	diguanylate cyclase activity
IM698_10370	COG2203	Gaf domain
IM698_10385	COG0471	metal ion transport
IM698_10390	COG2949	membrane
IM698_10395	COG0281	malic enzyme
IM698_10400	COG1643	Atp-dependent helicase
IM698_10410	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IM698_10445	COG0247	lactate metabolic process
IM698_10445	COG0277	FAD linked oxidase domain protein
IM698_10460	COG2986	histidine ammonia-lyase
IM698_10465	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IM698_10470	COG0010	Belongs to the arginase family
IM698_10475	COG1228	amidohydrolase
IM698_10485	COG4326	sporulation control protein
IM698_10505	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IM698_10510	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IM698_10515	COG3097	Belongs to the UPF0267 family
IM698_10530	COG0488	(ABC) transporter
IM698_10535	COG1309	transcriptional regulator
IM698_10545	COG1166	arginine decarboxylase activity
IM698_10550	COG0010	Belongs to the arginase family
IM698_10560	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IM698_10565	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM698_10570	COG0800	Aldolase
IM698_10575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM698_10580	COG1917	Cupin 2, conserved barrel domain protein
IM698_10605	COG3639	organic phosphonate transmembrane transporter activity
IM698_10610	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IM698_10620	COG2186	Transcriptional regulator
IM698_10635	COG3181	Tripartite tricarboxylate transporter family receptor
IM698_10645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM698_10660	COG0840	transmembrane signaling receptor activity
IM698_10695	COG2186	Transcriptional regulator
IM698_10700	COG1028	Short-chain dehydrogenase reductase Sdr
IM698_10705	COG2186	Transcriptional regulator
IM698_10710	COG0517	IMP dehydrogenase activity
IM698_10715	COG2176	DNA-directed DNA polymerase activity
IM698_10735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM698_10760	COG3033	Beta-eliminating lyase
IM698_10805	COG0471	metal ion transport
IM698_10810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM698_10810	COG4191	Histidine kinase
IM698_10835	COG0454	-acetyltransferase
IM698_10850	COG0730	response to heat
IM698_10865	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IM698_10870	COG1280	lysine exporter protein (LysE YggA)
IM698_10875	COG1115	amino acid carrier protein
IM698_10930	COG1115	amino acid carrier protein
IM698_10945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM698_10960	COG3290	protein histidine kinase activity
IM698_10965	COG4565	transcriptional regulatory protein
IM698_10970	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IM698_10975	COG0363	glucosamine-6-phosphate deaminase activity
IM698_10980	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IM698_10990	COG4628	conserved protein (DUF2132)
IM698_11025	COG3437	response regulator, receiver
IM698_11035	COG0515	serine threonine protein kinase
IM698_11140	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IM698_11150	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IM698_11155	COG0372	Belongs to the citrate synthase family
IM698_11160	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IM698_11195	COG0561	phosphatase activity
IM698_11200	COG0602	queuosine metabolic process
IM698_11205	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IM698_11210	COG3706	GGDEF domain
IM698_11220	COG2885	chlorophyll binding
IM698_11245	COG1254	Belongs to the acylphosphatase family
IM698_11250	COG2920	part of a sulfur-relay system
IM698_11255	COG0670	Belongs to the BI1 family
IM698_11260	COG1126	abc transporter atp-binding protein
IM698_11265	COG0765	amino acid transport
IM698_11270	COG4597	amino acid ABC transporter
IM698_11275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM698_11285	COG1666	GTP binding
IM698_11290	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IM698_11295	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IM698_11295	COG0574	Belongs to the PEP-utilizing enzyme family
IM698_11310	COG2996	Protein conserved in bacteria
IM698_11315	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
IM698_11315	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IM698_11320	COG3008	intermembrane lipid transfer
IM698_11325	COG2995	paraquat-inducible protein a
IM698_11330	COG1132	(ABC) transporter
IM698_11335	COG1956	GAF domain-containing protein
IM698_11340	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
IM698_11355	COG0308	aminopeptidase N
IM698_11365	COG2902	Dehydrogenase
IM698_11370	COG0167	dihydroorotate dehydrogenase activity
IM698_11380	COG0116	Belongs to the methyltransferase superfamily
IM698_11380	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IM698_11390	COG0488	(ABC) transporter
IM698_11410	COG1067	ATP-dependent peptidase activity
IM698_11415	COG3120	sequence-specific DNA binding
IM698_11445	COG2205	protein histidine kinase activity
IM698_11445	COG0784	Response regulator, receiver
IM698_11460	COG3278	Belongs to the heme-copper respiratory oxidase family
IM698_11475	COG2010	Cytochrome c
IM698_11485	COG2217	Heavy metal translocating P-type atpase
IM698_11500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IM698_11505	COG0589	response to stress
IM698_11510	COG0037	tRNA processing
IM698_11530	COG3842	ATPase activity
IM698_11540	COG1177	transmembrane transport
IM698_11550	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IM698_11555	COG2199	diguanylate cyclase activity
IM698_11555	COG2203	Gaf domain
IM698_11560	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IM698_11565	COG0004	ammonium transporteR
IM698_11580	COG0437	4 iron, 4 sulfur cluster binding
IM698_11585	COG0243	molybdopterin cofactor binding
IM698_11585	COG3383	formate dehydrogenase (NAD+) activity
IM698_11595	COG3381	protein complex oligomerization
IM698_11615	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IM698_11630	COG3220	belongs to the UPF0276 family
IM698_11645	COG1271	oxidase subunit
IM698_11650	COG1294	oxidase, subunit
IM698_11660	COG0488	(ABC) transporter
IM698_11675	COG4191	Histidine kinase
IM698_11680	COG2204	response regulator
IM698_11690	COG4662	Binding-protein-dependent transport system inner membrane component
IM698_11695	COG3842	ATPase activity
IM698_11700	COG0746	molybdenum cofactor guanylyltransferase activity
IM698_11705	COG0303	'Molybdopterin
IM698_11715	COG1940	carbohydrate kinase activity
IM698_11720	COG3148	PFAM DTW domain containing protein
IM698_11730	COG0840	transmembrane signaling receptor activity
IM698_11735	COG0791	NLP P60 protein
IM698_11745	COG3001	Fructosamine kinase
IM698_11755	COG0307	riboflavin synthase, alpha
IM698_11760	COG0534	Mate efflux family protein
IM698_11765	COG1793	dna ligase
IM698_11795	COG4176	ABC-type proline glycine betaine transport system permease component
IM698_11800	COG3448	diguanylate cyclase activity
IM698_11800	COG4175	Glycine betaine
IM698_11810	COG2204	response regulator
IM698_11845	COG0840	transmembrane signaling receptor activity
IM698_11900	COG2871	sodium ion transport
IM698_11905	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IM698_11920	COG3118	belongs to the thioredoxin family
IM698_11925	COG0513	Belongs to the DEAD box helicase family
IM698_11930	COG0248	Ppx GppA phosphatase
IM698_11935	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IM698_11945	COG0514	ATP-dependent DNA helicase (RecQ)
IM698_11950	COG2962	Rard protein
IM698_11960	COG1280	lysine exporter protein (LysE YggA)
IM698_11965	COG0405	Gamma-glutamyltransferase
IM698_11975	COG0210	DNA helicase
IM698_11985	COG3220	belongs to the UPF0276 family
IM698_12015	COG0006	proline dipeptidase activity
IM698_12015	COG0006	proline dipeptidase activity
IM698_12025	COG2022	thiamine diphosphate biosynthetic process
IM698_12030	COG2104	thiamine diphosphate biosynthetic process
IM698_12035	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IM698_12040	COG0352	thiamine-phosphate diphosphorylase activity
IM698_12045	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IM698_12055	COG2132	Multicopper oxidase
IM698_12100	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IM698_12110	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IM698_12115	COG0408	coproporphyrinogen oxidase activity
IM698_12120	COG0009	L-threonylcarbamoyladenylate synthase
IM698_12125	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IM698_12130	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IM698_12135	COG0551	DNA topoisomerase type I activity
IM698_12140	COG2922	Belongs to the Smg family
IM698_12145	COG0758	DNA mediated transformation
IM698_12155	COG0242	peptide deformylase activity
IM698_12160	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IM698_12165	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IM698_12165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IM698_12170	COG0569	domain protein
IM698_12175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IM698_12185	COG1272	protein, Hemolysin III
IM698_12190	COG4326	sporulation control protein
IM698_12200	COG3084	Protein conserved in bacteria
IM698_12210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IM698_12215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IM698_12225	COG0606	chelatase, subunit chli
IM698_12235	COG3978	acetolactate synthase activity
IM698_12240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IM698_12245	COG0129	dihydroxy-acid dehydratase activity
IM698_12255	COG0583	DNA-binding transcription factor activity
IM698_12260	COG2814	Major facilitator Superfamily
IM698_12270	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IM698_12275	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IM698_12280	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IM698_12285	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IM698_12290	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IM698_12295	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IM698_12310	COG3312	ion transport
IM698_12315	COG1475	DNA binding
IM698_12320	COG1192	Involved in chromosome partitioning
IM698_12325	COG0357	Ribosomal RNA small subunit methyltransferase G
IM698_12330	COG0445	tRNA wobble uridine modification
IM698_12335	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IM698_12345	COG0706	membrane insertase activity
IM698_12350	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IM698_12355	COG0594	ribonuclease P activity
IM698_12360	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IM698_12365	COG1126	abc transporter atp-binding protein
IM698_12380	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IM698_12385	COG0592	DNA-directed DNA polymerase activity
IM698_12390	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IM698_12395	COG0187	DNA topoisomerase II activity
IM698_12405	COG3977	Valine--pyruvate aminotransferase
IM698_12410	COG0366	Alpha amylase catalytic
IM698_12415	COG0751	glycine-tRNA ligase activity
IM698_12420	COG0752	glycyl-tRNA synthetase alpha subunit
IM698_12425	COG2119	membrane
IM698_12435	COG0425	Belongs to the sulfur carrier protein TusA family
IM698_12450	COG0604	alcohol dehydrogenase
IM698_12455	COG0183	Belongs to the thiolase family
IM698_12460	COG1250	3-hydroxyacyl-CoA dehydrogenase
IM698_12460	COG1024	Enoyl-CoA hydratase
IM698_12465	COG1739	Uncharacterized protein family UPF0029
IM698_12470	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IM698_12520	COG0583	DNA-binding transcription factor activity
IM698_12525	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IM698_12530	COG2960	long-chain fatty acid transporting porin activity
IM698_12535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM698_12540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM698_12545	COG1309	transcriptional regulator
IM698_12595	COG0601	transmembrane transport
IM698_12600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM698_12635	COG1805	sodium ion transport
IM698_12645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IM698_12650	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IM698_12660	COG1522	sequence-specific DNA binding
IM698_12670	COG0742	ribosomal rna small subunit methyltransferase
IM698_12685	COG0589	response to stress
IM698_12690	COG1528	Iron-storage protein
IM698_12700	COG2081	HI0933 family
IM698_12710	COG1322	Protein conserved in bacteria
IM698_12715	COG2226	methyltransferase
IM698_12720	COG3165	ubiquinone biosynthetic process from chorismate
IM698_12725	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IM698_12730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IM698_12735	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IM698_12740	COG0805	protein transport
IM698_12745	COG0084	hydrolase, TatD family'
IM698_12760	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IM698_12760	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IM698_12785	COG3078	GTPase activator activity
IM698_12810	COG3852	Histidine kinase
IM698_12820	COG0174	glutamine synthetase
IM698_12825	COG1217	gtp-binding protein TYPA
IM698_12840	COG1295	ribonuclease BN
IM698_12845	COG1490	D-aminoacyl-tRNA deacylase activity
IM698_12850	COG0456	acetyltransferase
IM698_12860	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IM698_12870	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IM698_12875	COG3031	protein transport across the cell outer membrane
IM698_12885	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IM698_12890	COG1459	type II secretion system
IM698_12895	COG2165	general secretion pathway protein
IM698_12900	COG2165	general secretion pathway protein
IM698_12905	COG2165	general secretion pathway protein
IM698_12910	COG4795	General secretion pathway protein
IM698_12915	COG3156	type II secretion system protein K
IM698_12920	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IM698_12925	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IM698_12935	COG1218	3'(2'),5'-bisphosphate nucleotidase
IM698_12940	COG0494	nUDIX hydrolase
IM698_12945	COG0316	Belongs to the HesB IscA family
IM698_12945	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IM698_12950	COG1040	competence protein
IM698_12955	COG0596	Alpha beta hydrolase
IM698_12965	COG2183	response to ionizing radiation
IM698_12970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IM698_12985	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IM698_12990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IM698_12995	COG1758	RNA polymerase activity
IM698_13000	COG0194	GDP metabolic process
IM698_13005	COG2252	PERMEase
IM698_13015	COG1278	Cold shock
IM698_13020	COG1561	YicC-like family, N-terminal region
IM698_13025	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IM698_13030	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IM698_13035	COG1560	Kdo2-lipid A biosynthetic process
IM698_13040	COG1309	transcriptional regulator
IM698_13050	COG2003	Belongs to the UPF0758 family
IM698_13055	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IM698_13060	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IM698_13070	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IM698_13085	COG0438	transferase activity, transferring glycosyl groups
IM698_13090	COG0463	Glycosyl transferase, family 2
IM698_13095	COG0859	PFAM glycosyl transferase family 9
IM698_13100	COG3642	lipopolysaccharide core region biosynthetic process
IM698_13120	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IM698_13150	COG1051	belongs to the nudix hydrolase family
IM698_13165	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
IM698_13185	COG1519	Transferase
IM698_13190	COG0859	PFAM glycosyl transferase family 9
IM698_13195	COG1560	Kdo2-lipid A biosynthetic process
IM698_13215	COG4942	peptidase
IM698_13220	COG1045	serine acetyltransferase
IM698_13230	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IM698_13235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM698_13270	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IM698_13275	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IM698_13280	COG2089	acid synthase
IM698_13285	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IM698_13290	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IM698_13295	COG1083	cytidylyl-transferase
IM698_13300	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IM698_13310	COG1028	Short-chain dehydrogenase reductase Sdr
IM698_13335	COG1215	transferase activity, transferring glycosyl groups
IM698_13345	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IM698_13395	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IM698_13415	COG0534	Mate efflux family protein
IM698_13420	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IM698_13435	COG3706	GGDEF domain
IM698_13440	COG1285	pathogenesis
IM698_13445	COG1509	lysine 2,3-aminomutase activity
IM698_13450	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IM698_13460	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
IM698_13465	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IM698_13470	COG1053	succinate dehydrogenase
IM698_13475	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IM698_13485	COG0840	transmembrane signaling receptor activity
IM698_13490	COG0471	metal ion transport
IM698_13490	COG0490	domain, Protein
IM698_13495	COG0688	phosphatidylethanolamine metabolic process
IM698_13500	COG1162	GTPase activity
IM698_13585	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IM698_13590	COG0802	atpase or kinase
IM698_13595	COG0860	N-Acetylmuramoyl-L-alanine amidase
IM698_13600	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IM698_13605	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IM698_13610	COG1923	regulation of RNA biosynthetic process
IM698_13615	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IM698_13620	COG0330	HflC and HflK could
IM698_13625	COG0330	HflC and HflK could
IM698_13630	COG3385	transposase activity
IM698_13635	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
IM698_13640	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IM698_13645	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IM698_13650	COG0402	S-adenosylhomocysteine deaminase activity
IM698_13655	COG0557	exoribonuclease II activity
IM698_13660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IM698_13665	COG0360	Binds together with S18 to 16S ribosomal RNA
IM698_13675	COG0359	binds to the 23S rRNA
IM698_13690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IM698_13700	COG0432	Pfam Uncharacterised protein family UPF0047
IM698_13705	COG0166	Belongs to the GPI family
IM698_13720	COG0735	belongs to the Fur family
IM698_13730	COG0583	DNA-binding transcription factor activity
IM698_13775	COG0582	viral genome integration into host DNA
IM698_13785	COG3081	Nucleoid-associated protein
IM698_13850	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IM698_13855	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IM698_13860	COG0175	sulfate reduction
IM698_13870	COG3071	HemY protein
IM698_13875	COG2959	enzyme of heme biosynthesis
IM698_13880	COG1587	Uroporphyrinogen-III synthase
IM698_13885	COG0181	hydroxymethylbilane synthase activity
IM698_13890	COG3072	Adenylate cyclase
IM698_13895	COG1965	Belongs to the frataxin family
IM698_13905	COG0019	diaminopimelate decarboxylase activity
IM698_13910	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IM698_13920	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IM698_13925	COG1011	Hydrolase
IM698_13930	COG2199	diguanylate cyclase activity
IM698_13930	COG2200	EAL domain
IM698_13930	COG3287	FIST C domain
IM698_13935	COG2200	EAL domain
IM698_13935	COG2199	diguanylate cyclase activity
IM698_13935	COG3287	FIST C domain
IM698_13940	COG3148	PFAM DTW domain containing protein
IM698_13955	COG0561	phosphatase activity
IM698_13960	COG2267	carboxylic ester hydrolase activity
IM698_13965	COG1280	lysine exporter protein (LysE YggA)
IM698_13970	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IM698_13975	COG0640	Transcriptional regulator
IM698_13980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IM698_14020	COG2095	MarC family integral membrane protein
IM698_14030	COG0742	ribosomal rna small subunit methyltransferase
IM698_14035	COG0552	protein localization to endoplasmic reticulum
IM698_14040	COG2884	Cell division ATP-binding protein ftsE
IM698_14045	COG2177	Part of the ABC transporter FtsEX involved in
IM698_14055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM698_14060	COG0705	Rhomboid family
IM698_14065	COG1580	Controls the rotational direction of flagella during chemotaxis
IM698_14070	COG3161	chorismate lyase activity
IM698_14075	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IM698_14080	COG2937	Belongs to the GPAT DAPAT family
IM698_14085	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IM698_14090	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IM698_14095	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IM698_14100	COG0534	Mate efflux family protein
IM698_14105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IM698_14120	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IM698_14125	COG4206	TonB-dependent receptor
IM698_14135	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IM698_14150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IM698_14160	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IM698_14170	COG1072	(Pantothenic acid kinase))
IM698_14200	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IM698_14205	COG0250	Participates in transcription elongation, termination and antitermination
IM698_14215	COG0081	regulation of translation
IM698_14220	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IM698_14225	COG0222	ribosome binding
IM698_14240	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
IM698_14245	COG2816	NAD+ diphosphatase activity
IM698_14255	COG1573	uracil-dna glycosylase
IM698_14265	COG3068	Protein conserved in bacteria
IM698_14270	COG1253	flavin adenine dinucleotide binding
IM698_14285	COG0151	Belongs to the GarS family
IM698_14290	COG0138	bifunctional purine biosynthesis protein purh
IM698_14295	COG0789	Transcriptional regulator
IM698_14300	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IM698_14305	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IM698_14310	COG2264	protein methyltransferase activity
IM698_14315	COG0439	Biotin carboxylase
IM698_14320	COG0511	ligase activity, forming carbon-carbon bonds
IM698_14325	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IM698_14330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IM698_14345	COG2814	Major facilitator Superfamily
IM698_14350	COG0784	Response regulator, receiver
IM698_14350	COG2198	Histidine kinase
IM698_14350	COG2205	protein histidine kinase activity
IM698_14365	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM698_14375	COG3263	regulation of cellular component size
IM698_14385	COG4232	protein-disulfide reductase activity
IM698_14390	COG1438	arginine binding
IM698_14395	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
IM698_14400	COG0540	Belongs to the ATCase OTCase family
IM698_14405	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IM698_14420	COG1288	antiporter activity
IM698_14425	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IM698_14430	COG1027	Aspartate ammonia-lyase
IM698_14440	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IM698_14450	COG2205	protein histidine kinase activity
IM698_14455	COG0745	RESPONSE REGULATOR receiver
IM698_14465	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IM698_14470	COG0205	6-phosphofructokinase activity
IM698_14475	COG0149	triose-phosphate isomerase activity
IM698_14485	COG3152	Membrane
IM698_14500	COG1494	fructose-1,6-bisphosphatase
IM698_14505	COG3074	FtsZ-dependent cytokinesis
IM698_14510	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IM698_14515	COG1575	Belongs to the MenA family. Type 1 subfamily
IM698_14520	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IM698_14525	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IM698_14535	COG1609	Transcriptional regulator
IM698_14540	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IM698_14545	COG0254	rRNA binding
IM698_14550	COG0281	malic enzyme
IM698_14555	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
IM698_14560	COG0626	cystathionine gamma-synthase activity
IM698_14565	COG0460	homoserine dehydrogenase
IM698_14565	COG0527	aspartate kinase activity
IM698_14570	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IM698_14580	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IM698_14585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IM698_14590	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IM698_14605	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IM698_14605	COG0165	Argininosuccinate lyase
IM698_14615	COG0251	oxidation-reduction process
IM698_14620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IM698_14625	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IM698_14625	COG0678	peroxiredoxin activity
IM698_14635	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IM698_14670	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IM698_14680	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IM698_14685	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IM698_14690	COG0546	phosphoglycolate phosphatase activity
IM698_14695	COG0180	Tryptophanyl-tRNA synthetase
IM698_14705	COG0512	Glutamine amidotransferase of anthranilate synthase
IM698_14710	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IM698_14720	COG1012	belongs to the aldehyde dehydrogenase family
IM698_14730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IM698_14735	COG3954	Phosphoribulokinase
IM698_14740	COG3089	Belongs to the UPF0270 family
IM698_14745	COG0429	hydrolase of the alpha beta-hydrolase fold
IM698_14755	COG0488	(ABC) transporter
IM698_14760	COG2249	NAD(P)H dehydrogenase (quinone) activity
IM698_14775	COG1047	Peptidyl-prolyl cis-trans
IM698_14780	COG1446	asparaginase
IM698_14785	COG2900	Belongs to the SlyX family
IM698_14795	COG0545	Peptidyl-prolyl cis-trans isomerase
IM698_14800	COG2964	Protein conserved in bacteria
IM698_14805	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IM698_14810	COG2923	Belongs to the DsrF TusC family
IM698_14830	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IM698_14845	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IM698_14850	COG0088	Forms part of the polypeptide exit tunnel
IM698_14855	COG0089	rRNA binding
IM698_14860	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IM698_14865	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IM698_14875	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IM698_14880	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IM698_14890	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IM698_14895	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IM698_14900	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IM698_14905	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IM698_14910	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IM698_14915	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IM698_14920	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IM698_14925	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IM698_14930	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IM698_14935	COG1841	ribosomal large subunit assembly
IM698_14940	COG0200	Binds to the 23S rRNA
IM698_14945	COG0201	protein transport
IM698_14950	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IM698_14955	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IM698_14960	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IM698_14965	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IM698_14970	COG0202	RNA polymerase activity
IM698_14975	COG0203	ribosomal protein L17
IM698_14985	COG0545	Peptidyl-prolyl cis-trans isomerase
IM698_14990	COG3266	domain, Protein
IM698_14990	COG3061	Opacity-associated protein A
IM698_15000	COG2153	protein acetylation
IM698_15050	COG0737	Belongs to the 5'-nucleotidase family
IM698_15055	COG0175	sulfate reduction
IM698_15060	COG2895	sulfate adenylyltransferase (ATP) activity
IM698_15065	COG3273	potassium ion transport
IM698_15065	COG0471	metal ion transport
IM698_15070	COG0529	Catalyzes the synthesis of activated sulfate
IM698_15105	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IM698_15115	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IM698_15120	COG0729	surface antigen
IM698_15125	COG2911	Protein conserved in bacteria
IM698_15130	COG2105	PFAM AIG2 family protein
IM698_15140	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IM698_15145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IM698_15150	COG0163	prenyltransferase activity
IM698_15155	COG4143	(ABC) transporter
IM698_15160	COG1178	ABC-type Fe3 transport system permease component
IM698_15165	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
IM698_15170	COG3028	Belongs to the UPF0307 family
IM698_15175	COG0312	modulator of DNA gyrase
IM698_15180	COG2239	Acts as a magnesium transporter
IM698_15185	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM698_15190	COG1660	Displays ATPase and GTPase activities
IM698_15195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM698_15200	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IM698_15210	COG1137	ATPase activity
IM698_15215	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IM698_15225	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IM698_15230	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IM698_15230	COG0517	IMP dehydrogenase activity
IM698_15240	COG1127	ABC transporter
IM698_15245	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IM698_15250	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IM698_15255	COG2854	intermembrane phospholipid transfer
IM698_15265	COG5007	Belongs to the BolA IbaG family
IM698_15270	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IM698_15275	COG0204	Acyl-transferase
IM698_15280	COG0251	oxidation-reduction process
IM698_15285	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
IM698_15315	COG0456	acetyltransferase
IM698_15325	COG0525	valine-tRNA ligase activity
IM698_15330	COG2927	DNA polymerase III (CHI subunit)
IM698_15335	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IM698_15340	COG0795	lipopolysaccharide-transporting ATPase activity
IM698_15345	COG0795	lipopolysaccharide-transporting ATPase activity
IM698_15435	COG3071	HemY protein
IM698_15440	COG2959	enzyme of heme biosynthesis
IM698_15445	COG1587	Uroporphyrinogen-III synthase
IM698_15450	COG0181	hydroxymethylbilane synthase activity
IM698_15455	COG3072	Adenylate cyclase
IM698_15460	COG1965	Belongs to the frataxin family
IM698_15470	COG0019	diaminopimelate decarboxylase activity
IM698_15475	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IM698_15485	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IM698_15490	COG1011	Hydrolase
IM698_15495	COG2199	diguanylate cyclase activity
IM698_15495	COG2200	EAL domain
IM698_15495	COG3287	FIST C domain
IM698_15500	COG2199	diguanylate cyclase activity
IM698_15500	COG2200	EAL domain
IM698_15500	COG3287	FIST C domain
IM698_15505	COG3148	PFAM DTW domain containing protein
IM698_15520	COG0561	phosphatase activity
IM698_15525	COG2267	carboxylic ester hydrolase activity
IM698_15530	COG1280	lysine exporter protein (LysE YggA)
IM698_15535	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IM698_15540	COG0640	Transcriptional regulator
IM698_15545	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IM698_15585	COG2095	MarC family integral membrane protein
IM698_15595	COG0742	ribosomal rna small subunit methyltransferase
IM698_15600	COG0552	protein localization to endoplasmic reticulum
IM698_15605	COG2884	Cell division ATP-binding protein ftsE
IM698_15610	COG2177	Part of the ABC transporter FtsEX involved in
IM698_15620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM698_15625	COG0705	Rhomboid family
IM698_15630	COG1580	Controls the rotational direction of flagella during chemotaxis
IM698_15635	COG3161	chorismate lyase activity
IM698_15640	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IM698_15645	COG2937	Belongs to the GPAT DAPAT family
IM698_15650	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IM698_15655	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IM698_15660	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IM698_15665	COG0534	Mate efflux family protein
IM698_15670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IM698_15685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IM698_15690	COG4206	TonB-dependent receptor
IM698_15700	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IM698_15750	COG0840	transmembrane signaling receptor activity
IM698_15800	COG5002	protein histidine kinase activity
IM698_15805	COG1881	PFAM PEBP family protein
IM698_15815	COG2807	transmembrane transport
IM698_15850	COG1280	lysine exporter protein (LysE YggA)
IM698_15870	COG0534	Mate efflux family protein
IM698_15895	COG0509	glycine decarboxylation via glycine cleavage system
IM698_15935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IM698_15940	COG3706	GGDEF domain
IM698_15945	COG2759	Belongs to the formate--tetrahydrofolate ligase family
IM698_15950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM698_15965	COG0784	Response regulator, receiver
IM698_15965	COG3437	response regulator, receiver
IM698_15970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IM698_15980	COG0814	amino acid
IM698_15985	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
IM698_15990	COG0513	Belongs to the DEAD box helicase family
IM698_16015	COG2200	EAL domain
IM698_16030	COG3038	cytochrome b561
IM698_16035	COG2353	YceI-like domain
IM698_16040	COG2116	formate transmembrane transporter activity
IM698_16045	COG0583	DNA-binding transcription factor activity
IM698_16055	COG3593	DNA synthesis involved in DNA repair
IM698_16060	COG0737	Belongs to the 5'-nucleotidase family
IM698_16065	COG0861	Integral membrane protein TerC family
IM698_16080	COG0513	Belongs to the DEAD box helicase family
IM698_16085	COG0729	surface antigen
IM698_16090	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IM698_16095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IM698_16115	COG1566	PFAM secretion protein HlyD family protein
IM698_16125	COG2985	domain, Protein
IM698_16135	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
IM698_16150	COG0583	DNA-binding transcription factor activity
IM698_16165	COG2267	carboxylic ester hydrolase activity
IM698_16170	COG2067	long-chain fatty acid transport protein
IM698_16180	COG0501	Belongs to the peptidase M48B family
IM698_16185	COG2050	protein possibly involved in aromatic compounds catabolism
IM698_16195	COG4533	DNA binding
IM698_16225	COG0768	penicillin binding
IM698_16235	COG5001	Diguanylate cyclase
IM698_16235	COG1716	ATPase activity
IM698_16240	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IM698_16250	COG4181	ATPase activity
IM698_16255	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IM698_16265	COG1984	allophanate hydrolase subunit 2
IM698_16290	COG3300	MHYT domain
IM698_16290	COG5001	Diguanylate cyclase
IM698_16300	COG1629	transport
IM698_16300	COG4771	TonB-dependent receptor
IM698_16305	COG0583	DNA-binding transcription factor activity
IM698_16310	COG0045	succinate-CoA ligase (ADP-forming) activity
IM698_16310	COG1042	CoA-binding domain protein
IM698_16310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM698_16315	COG3266	domain, Protein
IM698_16320	COG1181	Belongs to the D-alanine--D-alanine ligase family
IM698_16335	COG0023	Translation Initiation Factor
IM698_16340	COG3140	Belongs to the UPF0181 family
IM698_16365	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IM698_16370	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IM698_16385	COG3706	GGDEF domain
IM698_16395	COG2203	Gaf domain
IM698_16395	COG3706	GGDEF domain
IM698_16395	COG4251	negative regulation of phosphorylation
IM698_16395	COG5001	Diguanylate cyclase
IM698_16405	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IM698_16410	COG4149	molybdate abc transporter
IM698_16415	COG0725	ABC transporter, periplasmic molybdate-binding protein
IM698_16435	COG0488	(ABC) transporter
IM698_16440	COG4067	protein conserved in archaea
IM698_16440	COG0189	ligase activity
IM698_16450	COG0602	queuosine metabolic process
IM698_16455	COG1328	CTP reductase activity
IM698_16465	COG2391	methyltransferase activity
IM698_16485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IM698_16490	COG3118	belongs to the thioredoxin family
IM698_16500	COG0318	PFAM AMP-dependent synthetase and ligase
IM698_16530	COG0534	Mate efflux family protein
IM698_16555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IM698_16555	COG1321	iron dependent repressor
IM698_16560	COG1121	(ABC) transporter
IM698_16565	COG0803	Belongs to the bacterial solute-binding protein 9 family
IM698_16610	COG0848	biopolymer transport protein
IM698_16615	COG0811	peptide transport
IM698_16620	COG0811	peptide transport
IM698_16630	COG4774	siderophore transport
IM698_16635	COG1301	dicarboxylic acid transport
IM698_16640	COG2205	protein histidine kinase activity
IM698_16645	COG0745	RESPONSE REGULATOR receiver
IM698_16660	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IM698_16660	COG1648	precorrin-2 dehydrogenase activity
IM698_16665	COG2116	formate transmembrane transporter activity
IM698_16675	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IM698_16735	COG2425	protein containing a von Willebrand factor type A (vWA) domain
IM698_16745	COG0494	nUDIX hydrolase
IM698_16750	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
IM698_16800	COG3706	GGDEF domain
IM698_16830	COG1929	Belongs to the glycerate kinase type-1 family
IM698_16835	COG0383	alpha-mannosidase activity
IM698_16840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM698_16840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM698_16840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM698_16845	COG2188	Transcriptional regulator
IM698_16870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM698_16875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM698_16880	COG2067	long-chain fatty acid transport protein
IM698_16885	COG2267	carboxylic ester hydrolase activity
IM698_16900	COG3069	C4-dicarboxylate transmembrane transporter activity
IM698_16905	COG2197	response regulator
IM698_16910	COG3850	Histidine kinase
IM698_16925	COG0243	molybdopterin cofactor binding
IM698_16955	COG0183	Belongs to the thiolase family
IM698_17000	COG0745	RESPONSE REGULATOR receiver
IM698_17030	COG0513	Belongs to the DEAD box helicase family
IM698_17035	COG0523	cobalamin synthesis protein
IM698_17040	COG0038	chloride channel
IM698_17050	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IM698_17060	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IM698_17065	COG1175	transmembrane transport
IM698_17075	COG1609	Transcriptional regulator
IM698_17080	COG1017	nitric oxide dioxygenase activity
IM698_17080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IM698_17085	COG3604	Transcriptional regulator
IM698_17105	COG0545	Peptidyl-prolyl cis-trans isomerase
IM698_17110	COG1309	transcriptional regulator
IM698_17115	COG2130	NADP-dependent
IM698_17125	COG0564	pseudouridine synthase activity
IM698_17135	COG1686	Belongs to the peptidase S11 family
IM698_17150	COG3706	GGDEF domain
IM698_17160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IM698_17170	COG3059	membrane
IM698_17210	COG2207	Transcriptional regulator
IM698_17215	COG1979	alcohol dehydrogenase
IM698_17220	COG1126	abc transporter atp-binding protein
IM698_17225	COG0765	amino acid transport
IM698_17235	COG0765	amino acid transport
IM698_17250	COG4977	sequence-specific DNA binding
IM698_17260	COG1280	lysine exporter protein (LysE YggA)
IM698_17290	COG2824	Alkylphosphonate utilization operon protein PhnA
IM698_17320	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM698_17325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM698_17355	COG1132	(ABC) transporter
IM698_17370	COG1902	pentaerythritol trinitrate reductase activity
IM698_17370	COG0446	pyridine nucleotide-disulphide oxidoreductase
IM698_17380	COG3710	Transcriptional regulator
IM698_17395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM698_17400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM698_17410	COG2985	domain, Protein
IM698_17430	COG1024	Enoyl-CoA hydratase
IM698_17460	COG1120	ATPase activity
IM698_17470	COG2133	pyrroloquinoline quinone binding
IM698_17475	COG1278	Cold shock
IM698_17490	COG4681	YaeQ
IM698_17500	COG0302	gtp cyclohydrolase
IM698_17505	COG0303	'Molybdopterin
IM698_17530	COG2897	thiosulfate sulfurtransferase activity
IM698_17535	COG5001	Diguanylate cyclase
IM698_17535	COG3706	GGDEF domain
IM698_17535	COG4251	negative regulation of phosphorylation
IM698_17535	COG2203	Gaf domain
IM698_17570	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IM698_17575	COG0840	transmembrane signaling receptor activity
IM698_17580	COG1522	sequence-specific DNA binding
IM698_17600	COG2814	Major facilitator Superfamily
IM698_17605	COG0583	DNA-binding transcription factor activity
IM698_17610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM698_17610	COG2198	Histidine kinase
IM698_17610	COG0784	Response regulator, receiver
IM698_17610	COG2205	protein histidine kinase activity
IM698_17615	COG3437	response regulator, receiver
IM698_17620	COG4604	ABC transporter, ATP-binding protein
IM698_17625	COG4605	iron ion homeostasis
IM698_17630	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM698_17635	COG4607	ABC-type enterochelin transport system periplasmic component
IM698_17665	COG0628	permease
IM698_17675	COG1566	PFAM secretion protein HlyD family protein
IM698_17685	COG3706	GGDEF domain
IM698_17710	COG0402	S-adenosylhomocysteine deaminase activity
IM698_17725	COG0583	DNA-binding transcription factor activity
IM698_17735	COG0352	thiamine-phosphate diphosphorylase activity
IM698_17745	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IM698_17750	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IM698_17755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IM698_17760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IM698_17765	COG1116	anion transmembrane transporter activity
IM698_17770	COG0351	phosphomethylpyrimidine kinase
IM698_17775	COG0697	spore germination
IM698_17805	COG3710	Transcriptional regulator
IM698_17845	COG1785	Belongs to the alkaline phosphatase family
IM698_17855	COG0516	GMP reductase activity
IM698_17880	COG0534	Mate efflux family protein
IM698_17885	COG0583	DNA-binding transcription factor activity
IM698_17890	COG0366	Alpha amylase catalytic
IM698_17905	COG0697	spore germination
IM698_17925	COG0604	alcohol dehydrogenase
IM698_18010	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IM698_18015	COG0513	Belongs to the DEAD box helicase family
IM698_18020	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
IM698_18035	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IM698_18070	COG2195	Cleaves the N-terminal amino acid of tripeptides
IM698_18080	COG0667	Aldo Keto reductase
IM698_18085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IM698_18095	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
IM698_18100	COG0513	Belongs to the DEAD box helicase family
IM698_18110	COG2176	DNA-directed DNA polymerase activity
IM698_18125	COG0513	Belongs to the DEAD box helicase family
IM698_18130	COG4989	oxidoreductase activity
IM698_18150	COG1538	Outer membrane efflux protein
IM698_18155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM698_18200	COG0668	transmembrane transport
IM698_18210	COG4232	protein-disulfide reductase activity
IM698_18215	COG3118	belongs to the thioredoxin family
IM698_18230	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IM698_18235	COG0697	spore germination
IM698_18250	COG2814	Major facilitator Superfamily
IM698_18255	COG0583	DNA-binding transcription factor activity
IM698_18260	COG5001	Diguanylate cyclase
IM698_18265	COG0739	heme binding
IM698_18290	COG3314	Sporulation integral membrane protein YlbJ
IM698_18300	COG0366	Alpha amylase catalytic
IM698_18305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IM698_18310	COG0784	Response regulator, receiver
IM698_18310	COG0835	chemotaxis
IM698_18315	COG2096	Adenosyltransferase
IM698_18320	COG0748	coenzyme F420 binding
IM698_18325	COG3721	Heme iron utilization protein
IM698_18335	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IM698_18340	COG0811	peptide transport
IM698_18345	COG0848	biopolymer transport protein
IM698_18355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM698_18360	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
IM698_18405	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IM698_18410	COG0633	Ferredoxin
IM698_18410	COG3217	Mosc domain protein beta barrel domain protein
IM698_18420	COG0418	dihydroorotase activity
IM698_18425	COG2354	Protein conserved in bacteria
IM698_18435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IM698_18450	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IM698_18450	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IM698_18455	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IM698_18460	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IM698_18465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM698_18495	COG0730	response to heat
IM698_18500	COG0280	phosphate acetyltransferase
IM698_18505	COG1414	Transcriptional regulator
IM698_18510	COG1012	belongs to the aldehyde dehydrogenase family
IM698_18555	COG0583	DNA-binding transcription factor activity
IM698_18580	COG1028	Short-chain dehydrogenase reductase Sdr
IM698_18595	COG3706	GGDEF domain
IM698_18615	COG0583	DNA-binding transcription factor activity
IM698_18635	COG1136	(ABC) transporter
IM698_18640	COG0577	efflux transmembrane transporter activity
IM698_18660	COG3119	arylsulfatase activity
IM698_18670	COG0641	radical SAM
IM698_18705	COG3833	ABC-type maltose transport systems, permease component
IM698_18710	COG1175	transmembrane transport
IM698_18720	COG3842	ATPase activity
IM698_18735	COG0840	transmembrane signaling receptor activity
IM698_18740	COG0714	Associated with various cellular activities
IM698_18755	COG2304	oxidoreductase activity
IM698_18760	COG2304	oxidoreductase activity
IM698_18775	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IM698_18780	COG0581	inorganic phosphate transmembrane transporter activity
IM698_18785	COG0573	inorganic phosphate transmembrane transporter activity
IM698_18795	COG0840	transmembrane signaling receptor activity
IM698_18805	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IM698_18810	COG3240	lipase activity
IM698_18815	COG0513	Belongs to the DEAD box helicase family
IM698_18825	COG1376	ErfK ybiS ycfS ynhG family protein
IM698_18825	COG1388	LysM domain
IM698_18830	COG0813	purine-nucleoside phosphorylase activity
IM698_18860	COG1566	PFAM secretion protein HlyD family protein
IM698_18865	COG4720	Psort location CytoplasmicMembrane, score
IM698_18870	COG1122	ATPase activity
IM698_18885	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IM698_18890	COG1640	4-alpha-glucanotransferase
IM698_18895	COG0058	SHG alpha-glucan phosphorylase activity
IM698_18900	COG2909	trisaccharide binding
IM698_18915	COG1999	signal sequence binding
IM698_18930	COG1162	GTPase activity
IM698_18935	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IM698_18945	COG4566	intracellular signal transduction
IM698_18975	COG3258	Cytochrome c
IM698_19015	COG4580	involved in the transport of maltose and maltodextrins
IM698_19035	COG0204	Acyl-transferase
IM698_19040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IM698_19045	COG3615	Tellurite resistance protein tehB
IM698_19050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IM698_19055	COG4667	esterase of the alpha-beta hydrolase superfamily
IM698_19060	COG0753	catalase activity
IM698_19065	COG1929	Belongs to the glycerate kinase type-1 family
IM698_19075	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IM698_19080	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IM698_19085	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IM698_19095	COG0561	phosphatase activity
IM698_19110	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
IM698_19115	COG1414	Transcriptional regulator
IM698_19120	COG3623	hexulose-6-phosphate isomerase
IM698_19140	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IM698_19145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IM698_19155	COG3623	hexulose-6-phosphate isomerase
IM698_19160	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
IM698_19165	COG0561	phosphatase activity
IM698_19230	COG0583	DNA-binding transcription factor activity
IM698_19235	COG3214	Protein conserved in bacteria
IM698_19245	COG0561	phosphatase activity
IM698_19275	COG0798	PFAM Bile acid sodium symporter
IM698_19280	COG0583	DNA-binding transcription factor activity
IM698_19290	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IM698_19295	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IM698_19300	COG1349	DNA-binding transcription factor activity
IM698_19305	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IM698_19310	COG1028	Short-chain dehydrogenase reductase Sdr
IM698_19315	COG0583	DNA-binding transcription factor activity
IM698_19325	COG1794	racemase activity, acting on amino acids and derivatives
IM698_19345	COG2957	Belongs to the agmatine deiminase family
IM698_19350	COG0531	amino acid
IM698_19355	COG0549	Belongs to the carbamate kinase family
IM698_19375	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IM698_19385	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IM698_19400	COG0583	DNA-binding transcription factor activity
IM698_19405	COG2814	Major facilitator Superfamily
IM698_19415	COG2197	response regulator
IM698_19445	COG0583	DNA-binding transcription factor activity
IM698_19450	COG0110	maltose O-acetyltransferase activity
IM698_19455	COG1609	Transcriptional regulator
IM698_19460	COG2723	6-phospho-beta-galactosidase activity
IM698_19475	COG0346	lactoylglutathione lyase activity
IM698_19490	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IM698_19495	COG0583	DNA-binding transcription factor activity
IM698_19500	COG0534	Mate efflux family protein
IM698_19505	COG1024	Enoyl-CoA hydratase
IM698_19510	COG0300	oxidoreductase activity
IM698_19520	COG2723	6-phospho-beta-galactosidase activity
IM698_19525	COG1263	PTS System
IM698_19525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM698_19530	COG3265	gluconokinase activity
IM698_19535	COG0129	dihydroxy-acid dehydratase activity
IM698_19540	COG1609	Transcriptional regulator
IM698_19590	COG0646	methionine synthase
IM698_19590	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IM698_19615	COG0604	alcohol dehydrogenase
IM698_19615	COG1028	Short-chain dehydrogenase reductase Sdr
IM698_19615	COG3321	synthase
IM698_19625	COG2814	Major facilitator Superfamily
IM698_19630	COG2207	Transcriptional regulator
IM698_19645	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IM698_19670	COG2207	Transcriptional regulator
IM698_19685	COG2188	Transcriptional regulator
IM698_19695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM698_19695	COG1263	PTS System
IM698_19700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM698_19705	COG0800	Aldolase
IM698_19710	COG2169	Transcriptional regulator
IM698_19715	COG1486	melibiose metabolic process
IM698_19720	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IM698_19740	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IM698_19745	COG1072	(Pantothenic acid kinase))
IM698_19755	COG1063	alcohol dehydrogenase
IM698_19760	COG2213	PTS system mannitol-specific
IM698_19765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM698_19780	COG1846	Transcriptional regulator
IM698_19805	COG1012	belongs to the aldehyde dehydrogenase family
IM698_19810	COG1309	transcriptional regulator
IM698_19820	COG0745	RESPONSE REGULATOR receiver
IM698_19825	COG2205	protein histidine kinase activity
IM698_19845	COG0579	oxidoreductase
IM698_19860	COG2204	response regulator
IM698_19875	COG0800	Aldolase
IM698_19880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM698_19885	COG4145	pantothenate transmembrane transporter activity
IM698_19895	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IM698_19920	COG2194	sulfuric ester hydrolase activity
IM698_19945	COG1132	(ABC) transporter
IM698_19980	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM698_20005	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IM698_20015	COG0259	pyridoxamine-phosphate oxidase activity
IM698_20055	COG1444	tRNA N-acetyltransferase activity
IM698_20080	COG4608	Belongs to the ABC transporter superfamily
IM698_20085	COG0444	Belongs to the ABC transporter superfamily
IM698_20095	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
IM698_20095	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IM698_20110	COG4221	oxidoreductase activity
IM698_20125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM698_20140	COG0765	amino acid transport
IM698_20175	COG3842	ATPase activity
IM698_20185	COG0745	RESPONSE REGULATOR receiver
IM698_20190	COG2205	protein histidine kinase activity
IM698_20210	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IM698_20220	COG0625	glutathione transferase activity
IM698_20240	COG0604	alcohol dehydrogenase
IM698_20240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM698_20240	COG3321	synthase
IM698_20240	COG4221	oxidoreductase activity
IM698_20245	COG0583	DNA-binding transcription factor activity
IM698_20250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IM698_20255	COG3186	Phenylalanine-4-hydroxylase
IM698_20280	COG0217	transcriptional regulatory protein
IM698_20295	COG2084	Dehydrogenase
IM698_20310	COG0583	DNA-binding transcription factor activity
IM698_20325	COG1136	(ABC) transporter
IM698_20330	COG4591	ABC-type transport system involved in lipoprotein release permease component
IM698_20345	COG3275	phosphorelay sensor kinase activity
IM698_20350	COG3279	Response regulator of the LytR AlgR family
IM698_20355	COG0612	Peptidase, M16
IM698_20365	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IM698_20370	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IM698_20385	COG0270	DNA (cytosine-5-)-methyltransferase activity
IM698_20390	COG1902	pentaerythritol trinitrate reductase activity
IM698_20395	COG2814	Major facilitator Superfamily
IM698_20400	COG1028	Short-chain dehydrogenase reductase Sdr
IM698_20415	COG2205	protein histidine kinase activity
IM698_20420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM698_20420	COG1263	PTS System
IM698_20435	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IM698_20445	COG0724	RNA recognition motif
IM698_20470	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IM698_20485	COG4221	oxidoreductase activity
IM698_20495	COG0415	Belongs to the DNA photolyase family
IM698_20505	COG3806	Anti-sigma factor
IM698_20510	COG1595	DNA-templated transcription, initiation
IM698_20520	COG1942	4-Oxalocrotonate Tautomerase
IM698_20535	COG0786	glutamate:sodium symporter activity
IM698_20560	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM698_20560	COG2213	PTS system mannitol-specific
IM698_20565	COG0246	Mannitol dehydrogenase
IM698_20570	COG3722	fumarate hydratase activity
IM698_20575	COG0363	glucosamine-6-phosphate deaminase activity
IM698_20595	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IM698_20610	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IM698_20620	COG3366	ferrous iron transmembrane transporter activity
IM698_20625	COG0700	Nucleoside recognition
IM698_20630	COG3788	relative of glutathione S-transferase, MAPEG superfamily
IM698_20675	COG0596	Alpha beta hydrolase
IM698_20690	COG3123	guanosine phosphorylase activity
IM698_20695	COG1741	Belongs to the pirin family
IM698_20725	COG2197	response regulator
IM698_20730	COG3851	Histidine kinase
IM698_20735	COG2271	Major facilitator Superfamily
IM698_20755	COG1054	Belongs to the UPF0176 family
IM698_20770	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IM698_20775	COG0583	DNA-binding transcription factor activity
IM698_20780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM698_20785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IM698_20785	COG2207	Transcriptional regulator
IM698_20790	COG0534	Mate efflux family protein
IM698_20800	COG4172	Belongs to the ABC transporter superfamily
IM698_20805	COG0747	negative chemotaxis
IM698_20825	COG1304	FMN binding
IM698_20830	COG1620	l-lactate permease
IM698_20835	COG0583	DNA-binding transcription factor activity
IM698_20840	COG1505	serine-type exopeptidase activity
IM698_20870	COG0395	ABC-type sugar transport system, permease component
IM698_20875	COG2723	6-phospho-beta-galactosidase activity
IM698_20880	COG3842	ATPase activity
IM698_20885	COG3459	Glycosyltransferase 36 associated
IM698_20890	COG2017	converts alpha-aldose to the beta-anomer
IM698_20900	COG1609	Transcriptional regulator
IM698_20905	COG4172	Belongs to the ABC transporter superfamily
IM698_20915	COG1067	ATP-dependent peptidase activity
IM698_20965	COG1846	Transcriptional regulator
IM698_20980	COG0583	DNA-binding transcription factor activity
IM698_20985	COG2259	Doxx family
IM698_20995	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IM698_21000	COG3960	tartronate-semialdehyde synthase activity
IM698_21005	COG3622	Belongs to the hyi family
IM698_21010	COG2084	Dehydrogenase
IM698_21025	COG2205	protein histidine kinase activity
IM698_21025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM698_21030	COG0745	RESPONSE REGULATOR receiver
IM698_21045	COG0402	S-adenosylhomocysteine deaminase activity
IM698_21050	COG3287	FIST C domain
IM698_21050	COG2199	diguanylate cyclase activity
IM698_21050	COG2200	EAL domain
IM698_21070	COG2252	PERMEase
IM698_21090	COG4266	Belongs to the allantoicase family
IM698_21095	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IM698_21105	COG1309	transcriptional regulator
IM698_21155	COG1073	alpha beta
IM698_21185	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
IM698_21235	COG0789	Transcriptional regulator
IM698_21240	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IM698_21250	COG0402	S-adenosylhomocysteine deaminase activity
IM698_21260	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IM698_21285	COG1418	mRNA catabolic process
IM698_21290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IM698_21295	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IM698_21335	COG0583	DNA-binding transcription factor activity
IM698_21340	COG0625	glutathione transferase activity
IM698_21345	COG0583	DNA-binding transcription factor activity
IM698_21360	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IM698_21365	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IM698_21370	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IM698_21395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM698_21400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM698_21405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM698_21410	COG0577	efflux transmembrane transporter activity
IM698_21410	COG1136	(ABC) transporter
IM698_21415	COG2205	protein histidine kinase activity
IM698_21420	COG0745	RESPONSE REGULATOR receiver
IM698_21430	COG1882	Formate acetyltransferase
IM698_21460	COG1609	Transcriptional regulator
IM698_21465	COG4948	Mandelate Racemase Muconate Lactonizing
IM698_21485	COG0698	ribose 5-phosphate isomerase
IM698_21505	COG4166	transmembrane transport
IM698_21510	COG0583	DNA-binding transcription factor activity
IM698_21535	COG0546	phosphoglycolate phosphatase activity
IM698_21540	COG3842	ATPase activity
IM698_21545	COG0765	amino acid transport
IM698_21555	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM698_21570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM698_21570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM698_21570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM698_21575	COG2207	Transcriptional regulator
IM698_21580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM698_21590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM698_21595	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM698_21610	COG0840	transmembrane signaling receptor activity
IM698_21615	COG0814	amino acid
IM698_21620	COG2814	Major facilitator Superfamily
IM698_21635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM698_21650	COG0840	transmembrane signaling receptor activity
IM698_21660	COG0583	DNA-binding transcription factor activity
IM698_21685	COG0583	DNA-binding transcription factor activity
IM698_21695	COG4948	Mandelate Racemase Muconate Lactonizing
IM698_21725	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IM698_21730	COG3639	organic phosphonate transmembrane transporter activity
IM698_21735	COG3639	organic phosphonate transmembrane transporter activity
IM698_21780	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IM698_21785	COG3047	cAMP biosynthetic process
IM698_21795	COG4221	oxidoreductase activity
IM698_21800	COG0583	DNA-binding transcription factor activity
IM698_21805	COG1733	regulation of RNA biosynthetic process
IM698_21810	COG1028	Short-chain dehydrogenase reductase Sdr
IM698_21825	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IM698_21855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IM698_21860	COG1595	DNA-templated transcription, initiation
IM698_21885	COG1901	pseudouridine methyltransferase
IM698_21940	COG0446	pyridine nucleotide-disulphide oxidoreductase
IM698_21955	COG2964	Protein conserved in bacteria
IM698_21970	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
IM698_21975	COG3639	organic phosphonate transmembrane transporter activity
IM698_21980	COG2188	Transcriptional regulator
IM698_21985	COG3624	Phosphonate C-P lyase system protein PhnG
IM698_21990	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
IM698_21995	COG3626	phosphonate metabolism
IM698_22000	COG3627	carbon phosphorus lyase activity
IM698_22005	COG4107	phosphonate C-P lyase system protein PhnK
IM698_22010	COG4778	phosphonate C-P lyase system protein PhnL
IM698_22015	COG3454	Phosphonate metabolism
IM698_22025	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IM698_22030	COG0110	maltose O-acetyltransferase activity
IM698_22035	COG0534	Mate efflux family protein
IM698_22065	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IM698_22070	COG2999	glutathione oxidoreductase activity
IM698_22080	COG0673	inositol 2-dehydrogenase activity
IM698_22100	COG0584	glycerophosphoryl diester phosphodiesterase
IM698_22105	COG3842	ATPase activity
IM698_22110	COG0395	ABC-type sugar transport system, permease component
IM698_22115	COG1175	transmembrane transport
IM698_22135	COG4067	protein conserved in archaea
IM698_22135	COG0189	ligase activity
IM698_22140	COG0189	ligase activity
IM698_22190	COG2814	Major facilitator Superfamily
IM698_22200	COG0564	pseudouridine synthase activity
IM698_22220	COG3385	transposase activity
IM698_22230	COG1131	(ABC) transporter
IM698_22235	COG2186	Transcriptional regulator
IM698_22240	COG5001	Diguanylate cyclase
IM698_22250	COG5001	Diguanylate cyclase
IM698_22260	COG0745	RESPONSE REGULATOR receiver
IM698_22265	COG2205	protein histidine kinase activity
IM698_22270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM698_22275	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IM698_22280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM698_22285	COG3037	sugar-specific permease SgaT UlaA
IM698_22300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IM698_22325	COG0745	RESPONSE REGULATOR receiver
IM698_22330	COG0642	Histidine kinase
IM698_22335	COG4106	trans-aconitate 2-methyltransferase activity
IM698_22355	COG0513	Belongs to the DEAD box helicase family
IM698_22370	COG3706	GGDEF domain
IM698_22375	COG1278	Cold shock
IM698_22380	COG0402	S-adenosylhomocysteine deaminase activity
IM698_22385	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IM698_22405	COG0583	DNA-binding transcription factor activity
IM698_22420	COG1566	PFAM secretion protein HlyD family protein
IM698_22435	COG0733	neurotransmitter:sodium symporter activity
IM698_22440	COG2197	response regulator
IM698_22445	COG3119	arylsulfatase activity
IM698_22450	COG0641	radical SAM
IM698_22465	COG0714	Associated with various cellular activities
IM698_22495	COG4413	Urea transporter
IM698_22510	COG0531	amino acid
IM698_22525	COG1280	lysine exporter protein (LysE YggA)
IM698_22540	COG1151	hydroxylamine reductase activity
IM698_22545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IM698_22570	COG2926	Belongs to the UPF0265 family
IM698_22580	COG3132	Protein of unknown function, DUF480
IM698_22585	COG2827	Endonuclease containing a URI domain
IM698_22615	COG0443	Heat shock 70 kDa protein
IM698_22625	COG0179	Fumarylacetoacetate (FAA) hydrolase
IM698_22630	COG1280	lysine exporter protein (LysE YggA)
IM698_22635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IM698_22645	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IM698_22655	COG1845	cytochrome c oxidase, subunit III
IM698_22675	COG1612	heme a metabolic process
IM698_22680	COG0109	protoheme IX farnesyltransferase activity
IM698_22695	COG3530	Putative quorum-sensing-regulated virulence factor
IM698_22700	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IM698_22715	COG0668	transmembrane transport
IM698_22720	COG0569	domain protein
IM698_22725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IM698_22730	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IM698_22730	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IM698_22735	COG1765	OsmC-like protein
IM698_22740	COG2885	chlorophyll binding
IM698_22750	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IM698_22760	COG1840	ABC-type Fe3 transport system, periplasmic component
IM698_22765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM698_22770	COG3842	ATPase activity
IM698_22790	COG2375	cellular response to nickel ion
IM698_22795	COG3104	oligopeptide transport
IM698_22800	COG1760	l-serine dehydratase
IM698_22820	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IM698_22825	COG1132	(ABC) transporter
IM698_22830	COG1132	(ABC) transporter
IM698_22855	COG0739	heme binding
IM698_22860	COG0393	Putative heavy-metal-binding
IM698_22875	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IM698_22880	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IM698_22900	COG0346	lactoylglutathione lyase activity
IM698_22915	COG2200	EAL domain
IM698_22925	COG2202	Pas domain
IM698_22925	COG2200	EAL domain
IM698_22925	COG2199	diguanylate cyclase activity
IM698_22935	COG0156	8-amino-7-oxononanoate synthase activity
IM698_22940	COG1063	alcohol dehydrogenase
IM698_22965	COG2249	NAD(P)H dehydrogenase (quinone) activity
IM698_22980	COG1454	alcohol dehydrogenase
IM698_22985	COG1011	Hydrolase
IM698_23015	COG1328	CTP reductase activity
IM698_23020	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IM698_23025	COG0583	DNA-binding transcription factor activity
IM698_23045	COG1289	transmembrane transporter activity
IM698_23050	COG0210	DNA helicase
IM698_23060	COG1803	Methylglyoxal synthase
IM698_23065	COG1879	ABC-type sugar transport system periplasmic component
IM698_23070	COG2198	Histidine kinase
IM698_23070	COG5002	protein histidine kinase activity
IM698_23070	COG0784	Response regulator, receiver
IM698_23095	COG3385	transposase activity
IM698_23125	COG0625	glutathione transferase activity
IM698_23130	COG3064	Membrane
IM698_23145	COG2205	protein histidine kinase activity
IM698_23150	COG0745	RESPONSE REGULATOR receiver
IM698_23185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM698_23185	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IM698_23185	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM698_23190	COG1105	Belongs to the carbohydrate kinase PfkB family
IM698_23195	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM698_23195	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM698_23200	COG1609	Transcriptional regulator
IM698_23205	COG0515	serine threonine protein kinase
IM698_23205	COG2815	serine threonine protein kinase
IM698_23210	COG2223	nitrite transmembrane transporter activity
IM698_23220	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IM698_23225	COG0243	molybdopterin cofactor binding
IM698_23250	COG1609	Transcriptional regulator
IM698_23255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM698_23260	COG1879	ABC-type sugar transport system periplasmic component
IM698_23265	COG1172	Belongs to the binding-protein-dependent transport system permease family
IM698_23270	COG1129	ABC transporter
IM698_23275	COG1869	D-ribose catabolic process
IM698_23295	COG4166	transmembrane transport
IM698_23300	COG4174	ABC transporter (Permease)
IM698_23305	COG4239	(ABC) transporter, permease
IM698_23310	COG4172	Belongs to the ABC transporter superfamily
IM698_23320	COG0583	DNA-binding transcription factor activity
IM698_23330	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IM698_23340	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IM698_23350	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IM698_23365	COG0356	it plays a direct role in the translocation of protons across the membrane
IM698_23375	COG0583	DNA-binding transcription factor activity
IM698_23385	COG1012	belongs to the aldehyde dehydrogenase family
IM698_23395	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IM698_23435	COG3278	Belongs to the heme-copper respiratory oxidase family
IM698_23455	COG3300	MHYT domain
IM698_23455	COG5001	Diguanylate cyclase
IM698_23465	COG0384	phenazine biosynthesis protein PhzF
IM698_23490	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
IM698_23505	COG2197	response regulator
IM698_23510	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IM698_23525	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
IM698_23535	COG2205	protein histidine kinase activity
IM698_23535	COG0784	Response regulator, receiver
IM698_23545	COG3119	arylsulfatase activity
IM698_23550	COG3119	arylsulfatase activity
IM698_23560	COG0714	Associated with various cellular activities
IM698_23590	COG0583	DNA-binding transcription factor activity
IM698_23595	COG1597	lipid kinase activity
IM698_23610	COG0641	radical SAM
IM698_23620	COG0405	Gamma-glutamyltransferase
IM698_23625	COG0840	transmembrane signaling receptor activity
IM698_23650	COG0784	Response regulator, receiver
IM698_23650	COG2205	protein histidine kinase activity
IM698_23650	COG5002	protein histidine kinase activity
IM698_23665	COG1132	(ABC) transporter
IM698_23670	COG1538	Outer membrane efflux protein
IM698_23675	COG2205	protein histidine kinase activity
IM698_23675	COG0784	Response regulator, receiver
IM698_23680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family