locus-tag	class	description
VV1_0006	COG0628	permease
VV1_0007	COG3264	Mechanosensitive ion channel
VV1_0007	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
VV1_0010	COG1127	ABC transporter
VV1_0011	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VV1_0017	COG1555	photosystem II stabilization
VV1_0018	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VV1_0019	COG0776	regulation of translation
VV1_0021	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VV1_0025	COG4191	Histidine kinase
VV1_0026	COG2204	response regulator
VV1_0028	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VV1_0029	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VV1_0030	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VV1_0032	COG3842	ATPase activity
VV1_0037	COG0745	RESPONSE REGULATOR receiver
VV1_0047	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VV1_0048	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VV1_0050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VV1_0052	COG1216	Glycosyl transferase, family 2
VV1_0053	COG2986	histidine ammonia-lyase
VV1_0058	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VV1_0060	COG1028	Short-chain dehydrogenase reductase Sdr
VV1_0065	COG1695	Transcriptional regulator
VV1_0120	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VV1_0125	COG5002	protein histidine kinase activity
VV1_0126	COG0745	RESPONSE REGULATOR receiver
VV1_0128	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VV1_0130	COG2951	lytic endotransglycosylase activity
VV1_0133	COG2894	cell division
VV1_0135	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
VV1_0136	COG0318	PFAM AMP-dependent synthetase and ligase
VV1_0137	COG0596	Alpha beta hydrolase
VV1_0140	COG1214	PFAM Peptidase M22, glycoprotease
VV1_0141	COG1199	ATP-dependent helicase activity
VV1_0143	COG0788	formyltetrahydrofolate deformylase activity
VV1_0144	COG3102	Protein conserved in bacteria
VV1_0148	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
VV1_0149	COG1918	ferrous iron import across plasma membrane
VV1_0151	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
VV1_0153	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VV1_0156	COG0508	dehydrogenase complex catalyzes the overall conversion of
VV1_0157	COG0567	Dehydrogenase, E1 component
VV1_0159	COG1053	succinate dehydrogenase
VV1_0160	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
VV1_0161	COG2009	succinate dehydrogenase
VV1_0163	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VV1_0165	COG0446	pyridine nucleotide-disulphide oxidoreductase
VV1_0167	COG0251	oxidation-reduction process
VV1_0168	COG2964	Protein conserved in bacteria
VV1_0169	COG0033	Phosphoglucomutase
VV1_0170	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
VV1_0171	COG0596	Alpha beta hydrolase
VV1_0173	COG0716	FMN binding
VV1_0176	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VV1_0179	COG1263	PTS System
VV1_0179	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VV1_0179	COG2190	(PTS) system
VV1_0180	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VV1_0181	COG1846	Transcriptional regulator
VV1_0181	COG1940	carbohydrate kinase activity
VV1_0182	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VV1_0182	COG4651	solute:proton antiporter activity
VV1_0183	COG0367	asparagine synthase
VV1_0185	COG3104	oligopeptide transport
VV1_0186	COG0840	transmembrane signaling receptor activity
VV1_0190	COG3710	Transcriptional regulator
VV1_0194	COG0622	Phosphoesterase
VV1_0199	COG1090	epimerase
VV1_0200	COG0300	oxidoreductase activity
VV1_0201	COG3118	belongs to the thioredoxin family
VV1_0202	COG0330	HflC and HflK could
VV1_0208	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
VV1_0209	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VV1_0210	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VV1_0211	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
VV1_0212	COG2190	(PTS) system
VV1_0213	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VV1_0214	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VV1_0215	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VV1_0216	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VV1_0218	COG3951	Flagellar rod assembly protein muramidase FlgJ
VV1_0218	COG1705	Flagellar rod assembly protein muramidase FlgJ
VV1_0221	COG4786	Flagellar basal body rod
VV1_0222	COG4787	bacterial-type flagellum-dependent cell motility
VV1_0223	COG1749	Flagellar hook protein flgE
VV1_0224	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
VV1_0225	COG1558	bacterial-type flagellum-dependent cell motility
VV1_0226	COG1815	bacterial-type flagellum-dependent cell motility
VV1_0227	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VV1_0228	COG0835	chemotaxis
VV1_0228	COG0784	Response regulator, receiver
VV1_0239	COG2217	Heavy metal translocating P-type atpase
VV1_0239	COG2608	mercury ion transmembrane transporter activity
VV1_0243	COG3735	TraB family
VV1_0245	COG2840	Smr protein MutS2
VV1_0246	COG1187	pseudouridine synthase activity
VV1_0250	COG2912	Transglutaminase-like superfamily
VV1_0251	COG3094	Invasion gene expression up-regulator, SirB
VV1_0252	COG2890	protein-(glutamine-N5) methyltransferase activity
VV1_0256	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
VV1_0265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VV1_0267	COG1702	phosphate starvation-inducible protein PhoH
VV1_0269	COG4535	Mg2 and Co2 transporter CorC
VV1_0271	COG2888	peptidyl-tyrosine sulfation
VV1_0274	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
VV1_0275	COG1466	dna polymerase III delta subunit
VV1_0276	COG0799	negative regulation of ribosome biogenesis
VV1_0278	COG0768	penicillin binding
VV1_0279	COG0772	Belongs to the SEDS family
VV1_0280	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VV1_0281	COG1686	Belongs to the peptidase S11 family
VV1_0288	COG0366	Alpha amylase catalytic
VV1_0289	COG1263	PTS System
VV1_0289	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VV1_0291	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VV1_0293	COG2011	ABC-type metal ion transport system permease component
VV1_0294	COG1464	Belongs to the NlpA lipoprotein family
VV1_0295	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
VV1_0299	COG3706	GGDEF domain
VV1_0300	COG1611	Belongs to the LOG family
VV1_0304	COG2363	Small membrane protein
VV1_0306	COG0583	DNA-binding transcription factor activity
VV1_0312	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VV1_0314	COG0142	geranyltranstransferase activity
VV1_0316	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VV1_0317	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
VV1_0323	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VV1_0323	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VV1_0331	COG2252	PERMEase
VV1_0333	COG2195	Cleaves the N-terminal amino acid of tripeptides
VV1_0342	COG0590	tRNA wobble adenosine to inosine editing
VV1_0343	COG0583	DNA-binding transcription factor activity
VV1_0344	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
VV1_0345	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
VV1_0346	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VV1_0367	COG0497	DNA recombination
VV1_0368	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VV1_0370	COG2867	negative regulation of translational initiation
VV1_0372	COG0582	viral genome integration into host DNA
VV1_0382	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VV1_0390	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VV1_0409	COG0009	L-threonylcarbamoyladenylate synthase
VV1_0413	COG0583	DNA-binding transcription factor activity
VV1_0415	COG1115	amino acid carrier protein
VV1_0416	COG1584	GPR1 FUN34 yaaH family protein
VV1_0419	COG0517	IMP dehydrogenase activity
VV1_0419	COG0516	GMP reductase activity
VV1_0421	COG2199	diguanylate cyclase activity
VV1_0421	COG2203	Gaf domain
VV1_0424	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VV1_0425	COG2976	Protein conserved in bacteria
VV1_0432	COG2975	iron-sulfur cluster assembly
VV1_0433	COG0633	Ferredoxin
VV1_0437	COG0822	iron-sulfur transferase activity
VV1_0440	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
VV1_0441	COG0483	inositol monophosphate 1-phosphatase activity
VV1_0442	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VV1_0443	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VV1_0444	COG1862	Preprotein translocase
VV1_0448	COG0517	IMP dehydrogenase activity
VV1_0450	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
VV1_0451	COG0583	DNA-binding transcription factor activity
VV1_0453	COG0450	alkyl hydroperoxide reductase
VV1_0460	COG0704	Plays a role in the regulation of phosphate uptake
VV1_0462	COG0581	inorganic phosphate transmembrane transporter activity
VV1_0463	COG0573	inorganic phosphate transmembrane transporter activity
VV1_0465	COG0248	Ppx GppA phosphatase
VV1_0467	COG5002	protein histidine kinase activity
VV1_0468	COG0745	RESPONSE REGULATOR receiver
VV1_0471	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VV1_0485	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VV1_0486	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VV1_0487	COG1605	Chorismate mutase
VV1_0487	COG0077	Prephenate dehydratase
VV1_0491	COG0488	(ABC) transporter
VV1_0493	COG0739	heme binding
VV1_0494	COG1605	Chorismate mutase
VV1_0494	COG0287	Prephenate dehydrogenase
VV1_0495	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VV1_0496	COG1472	Belongs to the glycosyl hydrolase 3 family
VV1_0501	COG1966	Carbon starvation protein
VV1_0502	COG3275	phosphorelay sensor kinase activity
VV1_0505	COG1047	Peptidyl-prolyl cis-trans
VV1_0508	COG0196	riboflavin kinase activity
VV1_0509	COG0728	peptidoglycan biosynthetic process
VV1_0512	COG0640	Transcriptional regulator
VV1_0513	COG0583	DNA-binding transcription factor activity
VV1_0514	COG1283	sodium-dependent phosphate transmembrane transporter activity
VV1_0518	COG0730	response to heat
VV1_0523	COG0667	Aldo Keto reductase
VV1_0527	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
VV1_0528	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VV1_0529	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VV1_0531	COG0716	FMN binding
VV1_0534	COG0513	Belongs to the DEAD box helicase family
VV1_0536	COG1115	amino acid carrier protein
VV1_0543	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
VV1_0548	COG0745	RESPONSE REGULATOR receiver
VV1_0550	COG0784	Response regulator, receiver
VV1_0550	COG2198	Histidine kinase
VV1_0550	COG5002	protein histidine kinase activity
VV1_0551	COG4251	negative regulation of phosphorylation
VV1_0551	COG3706	GGDEF domain
VV1_0551	COG2203	Gaf domain
VV1_0551	COG5001	Diguanylate cyclase
VV1_0552	COG1242	4 iron, 4 sulfur cluster binding
VV1_0553	COG0069	glutamate synthase activity
VV1_0553	COG0070	glutamate synthase
VV1_0553	COG0067	glutamate synthase
VV1_0555	COG0069	glutamate synthase activity
VV1_0555	COG0070	glutamate synthase
VV1_0555	COG0067	glutamate synthase
VV1_0556	COG0493	'glutamate synthase
VV1_0561	COG2860	membrane
VV1_0562	COG0583	DNA-binding transcription factor activity
VV1_0563	COG0730	response to heat
VV1_0568	COG0494	nUDIX hydrolase
VV1_0572	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VV1_0574	COG0849	cell division
VV1_0575	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VV1_0579	COG0772	Belongs to the SEDS family
VV1_0582	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VV1_0584	COG0768	penicillin binding
VV1_0585	COG3116	cell division
VV1_0588	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VV1_0589	COG3107	peptidoglycan biosynthetic process
VV1_0591	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VV1_0592	COG2823	Periplasmic or secreted lipoprotein
VV1_0593	COG2969	positive regulation of protein catabolic process
VV1_0594	COG0625	glutathione transferase activity
VV1_0595	COG2857	Cytochrome c1
VV1_0596	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VV1_0597	COG0723	plastoquinol--plastocyanin reductase activity
VV1_0600	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VV1_0601	COG3105	Protein conserved in bacteria
VV1_0603	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VV1_0604	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VV1_0606	COG0187	DNA topoisomerase II activity
VV1_0607	COG3150	esterase
VV1_0609	COG3151	Protein conserved in bacteria
VV1_0610	COG0494	nUDIX hydrolase
VV1_0612	COG1538	Outer membrane efflux protein
VV1_0616	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VV1_0617	COG3025	triphosphatase activity
VV1_0618	COG1392	Phosphate transport regulator
VV1_0619	COG0306	phosphate transporter
VV1_0620	COG4991	sh3 domain protein
VV1_0621	COG3409	Peptidoglycan-binding domain 1 protein
VV1_0621	COG3267	Type II secretory pathway component ExeA
VV1_0624	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VV1_0625	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
VV1_0627	COG0596	Alpha beta hydrolase
VV1_0629	COG0828	Belongs to the bacterial ribosomal protein bS21 family
VV1_0630	COG1610	YqeY-like protein
VV1_0632	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VV1_0637	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VV1_0638	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VV1_0638	COG2213	PTS system mannitol-specific
VV1_0640	COG3722	fumarate hydratase activity
VV1_0642	COG1349	DNA-binding transcription factor activity
VV1_0644	COG0469	pyruvate kinase activity
VV1_0646	COG3706	GGDEF domain
VV1_0647	COG0440	acetolactate synthase activity
VV1_0648	COG0028	Belongs to the TPP enzyme family
VV1_0649	COG1022	Amp-dependent synthetase and ligase
VV1_0667	COG3610	response to peptide
VV1_0668	COG2966	Psort location CytoplasmicMembrane, score
VV1_0671	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VV1_0672	COG0142	geranyltranstransferase activity
VV1_0677	COG0589	response to stress
VV1_0678	COG0204	Acyl-transferase
VV1_0680	COG5007	Belongs to the BolA IbaG family
VV1_0682	COG2854	intermembrane phospholipid transfer
VV1_0683	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VV1_0684	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VV1_0685	COG1127	ABC transporter
VV1_0687	COG0517	IMP dehydrogenase activity
VV1_0687	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
VV1_0688	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
VV1_0690	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VV1_0691	COG1137	ATPase activity
VV1_0693	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VV1_0694	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VV1_0695	COG1660	Displays ATPase and GTPase activities
VV1_0697	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VV1_0698	COG2239	Acts as a magnesium transporter
VV1_0699	COG0312	modulator of DNA gyrase
VV1_0700	COG3028	Belongs to the UPF0307 family
VV1_0702	COG1178	ABC-type Fe3 transport system permease component
VV1_0703	COG4143	(ABC) transporter
VV1_0705	COG0163	prenyltransferase activity
VV1_0706	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VV1_0710	COG2105	PFAM AIG2 family protein
VV1_0711	COG2911	Protein conserved in bacteria
VV1_0712	COG0729	surface antigen
VV1_0715	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VV1_0719	COG1136	(ABC) transporter
VV1_0719	COG0577	efflux transmembrane transporter activity
VV1_0724	COG3273	potassium ion transport
VV1_0724	COG0471	metal ion transport
VV1_0727	COG1648	precorrin-2 dehydrogenase activity
VV1_0727	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VV1_0728	COG0737	Belongs to the 5'-nucleotidase family
VV1_0730	COG2153	protein acetylation
VV1_0732	COG3266	domain, Protein
VV1_0732	COG3061	Opacity-associated protein A
VV1_0733	COG0545	Peptidyl-prolyl cis-trans isomerase
VV1_0738	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VV1_0740	COG0201	protein transport
VV1_0767	COG3064	Membrane
VV1_0769	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
VV1_0776	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VV1_0779	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
VV1_0780	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VV1_0786	COG1596	polysaccharide export
VV1_0795	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VV1_0798	COG0859	PFAM glycosyl transferase family 9
VV1_0799	COG1519	Transferase
VV1_0803	COG1083	cytidylyl-transferase
VV1_0807	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VV1_0808	COG2089	acid synthase
VV1_0810	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VV1_0813	COG3083	sulfuric ester hydrolase activity
VV1_0815	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VV1_0816	COG0859	PFAM glycosyl transferase family 9
VV1_0817	COG0463	Glycosyl transferase, family 2
VV1_0818	COG0859	PFAM glycosyl transferase family 9
VV1_0825	COG2003	Belongs to the UPF0758 family
VV1_0830	COG1560	Kdo2-lipid A biosynthetic process
VV1_0833	COG1561	YicC-like family, N-terminal region
VV1_0837	COG4608	Belongs to the ABC transporter superfamily
VV1_0838	COG0444	Belongs to the ABC transporter superfamily
VV1_0839	COG0747	negative chemotaxis
VV1_0840	COG4239	(ABC) transporter, permease
VV1_0841	COG4174	ABC transporter (Permease)
VV1_0842	COG4206	TonB-dependent receptor
VV1_0844	COG0811	peptide transport
VV1_0845	COG0811	peptide transport
VV1_0846	COG0848	biopolymer transport protein
VV1_0852	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VV1_0853	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VV1_0854	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VV1_0856	COG2233	PERMEase
VV1_0858	COG0745	RESPONSE REGULATOR receiver
VV1_0860	COG2183	response to ionizing radiation
VV1_0863	COG1040	competence protein
VV1_0865	COG0494	nUDIX hydrolase
VV1_0866	COG1218	3'(2'),5'-bisphosphate nucleotidase
VV1_0868	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VV1_0869	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VV1_0870	COG3156	type II secretion system protein K
VV1_0871	COG4795	General secretion pathway protein
VV1_0872	COG2165	general secretion pathway protein
VV1_0873	COG2165	general secretion pathway protein
VV1_0874	COG2165	general secretion pathway protein
VV1_0875	COG1459	type II secretion system
VV1_0876	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VV1_0878	COG3031	protein transport across the cell outer membrane
VV1_0879	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VV1_0883	COG0456	acetyltransferase
VV1_0889	COG0174	glutamine synthetase
VV1_0891	COG3852	Histidine kinase
VV1_0892	COG2204	response regulator
VV1_0894	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VV1_0901	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VV1_0901	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VV1_0903	COG0084	hydrolase, TatD family'
VV1_0904	COG0805	protein transport
VV1_0908	COG3165	ubiquinone biosynthetic process from chorismate
VV1_0910	COG1322	Protein conserved in bacteria
VV1_0914	COG3335	DDE superfamily endonuclease
VV1_0937	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
VV1_0938	COG3118	belongs to the thioredoxin family
VV1_0941	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
VV1_0943	COG0514	ATP-dependent DNA helicase (RecQ)
VV1_0944	COG2962	Rard protein
VV1_0946	COG1280	lysine exporter protein (LysE YggA)
VV1_0949	COG0210	DNA helicase
VV1_0958	COG0006	proline dipeptidase activity
VV1_0958	COG0006	proline dipeptidase activity
VV1_0962	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VV1_0966	COG2132	Multicopper oxidase
VV1_0969	COG3335	DDE superfamily endonuclease
VV1_0979	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VV1_0980	COG1739	Uncharacterized protein family UPF0029
VV1_0983	COG0604	alcohol dehydrogenase
VV1_0988	COG2119	membrane
VV1_0992	COG3977	Valine--pyruvate aminotransferase
VV1_0994	COG0071	Belongs to the small heat shock protein (HSP20) family
VV1_0996	COG0187	DNA topoisomerase II activity
VV1_0998	COG0592	DNA-directed DNA polymerase activity
VV1_1003	COG1126	abc transporter atp-binding protein
VV1_1009	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VV1_1012	COG1192	Involved in chromosome partitioning
VV1_1013	COG1475	DNA binding
VV1_1014	COG3312	ion transport
VV1_1019	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
VV1_1024	COG0765	amino acid transport
VV1_1026	COG2814	Major facilitator Superfamily
VV1_1027	COG0583	DNA-binding transcription factor activity
VV1_1030	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VV1_1031	COG3978	acetolactate synthase activity
VV1_1033	COG0606	chelatase, subunit chli
VV1_1035	COG0204	Acyl-transferase
VV1_1036	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VV1_1037	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VV1_1039	COG3084	Protein conserved in bacteria
VV1_1041	COG4326	sporulation control protein
VV1_1043	COG1272	protein, Hemolysin III
VV1_1044	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VV1_1045	COG0569	domain protein
VV1_1050	COG0758	DNA mediated transformation
VV1_1052	COG0551	DNA topoisomerase type I activity
VV1_1059	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
VV1_1074	COG3335	DDE superfamily endonuclease
VV1_1076	COG0583	DNA-binding transcription factor activity
VV1_1078	COG2960	long-chain fatty acid transporting porin activity
VV1_1079	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VV1_1080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VV1_1081	COG1309	transcriptional regulator
VV1_1085	COG4172	Belongs to the ABC transporter superfamily
VV1_1086	COG4166	transmembrane transport
VV1_1088	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VV1_1095	COG2815	serine threonine protein kinase
VV1_1095	COG0515	serine threonine protein kinase
VV1_1098	COG1609	Transcriptional regulator
VV1_1099	COG0129	dihydroxy-acid dehydratase activity
VV1_1100	COG3265	gluconokinase activity
VV1_1101	COG2610	gluconate transmembrane transporter activity
VV1_1102	COG0800	Aldolase
VV1_1105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VV1_1106	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VV1_1109	COG1522	sequence-specific DNA binding
VV1_1110	COG5001	Diguanylate cyclase
VV1_1110	COG5002	protein histidine kinase activity
VV1_1115	COG0589	response to stress
VV1_1116	COG1528	Iron-storage protein
VV1_1118	COG2081	HI0933 family
VV1_1120	COG2959	enzyme of heme biosynthesis
VV1_1123	COG3072	Adenylate cyclase
VV1_1126	COG0019	diaminopimelate decarboxylase activity
VV1_1130	COG1011	Hydrolase
VV1_1132	COG3287	FIST C domain
VV1_1132	COG2200	EAL domain
VV1_1132	COG2199	diguanylate cyclase activity
VV1_1136	COG0561	phosphatase activity
VV1_1137	COG2267	carboxylic ester hydrolase activity
VV1_1138	COG1280	lysine exporter protein (LysE YggA)
VV1_1139	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VV1_1140	COG0640	Transcriptional regulator
VV1_1141	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VV1_1151	COG2095	MarC family integral membrane protein
VV1_1153	COG0742	ribosomal rna small subunit methyltransferase
VV1_1154	COG0552	protein localization to endoplasmic reticulum
VV1_1155	COG2884	Cell division ATP-binding protein ftsE
VV1_1157	COG2177	Part of the ABC transporter FtsEX involved in
VV1_1161	COG0705	Rhomboid family
VV1_1162	COG1580	Controls the rotational direction of flagella during chemotaxis
VV1_1193	COG3335	DDE superfamily endonuclease
VV1_1195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VV1_1205	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VV1_1213	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
VV1_1220	COG1573	uracil-dna glycosylase
VV1_1221	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VV1_1222	COG3068	Protein conserved in bacteria
VV1_1223	COG1253	flavin adenine dinucleotide binding
VV1_1229	COG0789	Transcriptional regulator
VV1_1230	COG0840	transmembrane signaling receptor activity
VV1_1231	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VV1_1234	COG0439	Biotin carboxylase
VV1_1235	COG0511	ligase activity, forming carbon-carbon bonds
VV1_1241	COG2814	Major facilitator Superfamily
VV1_1242	COG2205	protein histidine kinase activity
VV1_1242	COG2198	Histidine kinase
VV1_1242	COG0784	Response regulator, receiver
VV1_1243	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VV1_1245	COG2095	MarC family integral membrane protein
VV1_1248	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VV1_1249	COG1027	Aspartate ammonia-lyase
VV1_1251	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
VV1_1253	COG2205	protein histidine kinase activity
VV1_1254	COG0745	RESPONSE REGULATOR receiver
VV1_1255	COG3678	ATP-independent chaperone mediated protein folding
VV1_1258	COG0534	Mate efflux family protein
VV1_1262	COG1285	pathogenesis
VV1_1263	COG1509	lysine 2,3-aminomutase activity
VV1_1268	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VV1_1269	COG1053	succinate dehydrogenase
VV1_1274	COG3385	transposase activity
VV1_1275	COG4942	peptidase
VV1_1276	COG1045	serine acetyltransferase
VV1_1280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VV1_1283	COG0471	metal ion transport
VV1_1289	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VV1_1290	COG0802	atpase or kinase
VV1_1291	COG0860	N-Acetylmuramoyl-L-alanine amidase
VV1_1295	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VV1_1296	COG0330	HflC and HflK could
VV1_1297	COG0330	HflC and HflK could
VV1_1298	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
VV1_1300	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
VV1_1303	COG0402	S-adenosylhomocysteine deaminase activity
VV1_1304	COG0557	exoribonuclease II activity
VV1_1318	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VV1_1319	COG3954	Phosphoribulokinase
VV1_1321	COG0429	hydrolase of the alpha beta-hydrolase fold
VV1_1323	COG0488	(ABC) transporter
VV1_1324	COG2249	NAD(P)H dehydrogenase (quinone) activity
VV1_1327	COG1047	Peptidyl-prolyl cis-trans
VV1_1331	COG0545	Peptidyl-prolyl cis-trans isomerase
VV1_1332	COG2964	Protein conserved in bacteria
VV1_1335	COG2168	tRNA wobble position uridine thiolation
VV1_1338	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VV1_1340	COG2906	2 iron, 2 sulfur cluster binding
VV1_1342	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VV1_1349	COG1494	fructose-1,6-bisphosphatase
VV1_1353	COG1575	Belongs to the MenA family. Type 1 subfamily
VV1_1358	COG1609	Transcriptional regulator
VV1_1359	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VV1_1361	COG0281	malic enzyme
VV1_1364	COG0626	cystathionine gamma-synthase activity
VV1_1365	COG0527	aspartate kinase activity
VV1_1365	COG0460	homoserine dehydrogenase
VV1_1366	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VV1_1376	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
VV1_1385	COG0338	D12 class N6 adenine-specific DNA methyltransferase
VV1_1386	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VV1_1392	COG0305	Participates in initiation and elongation during chromosome replication
VV1_1395	COG0432	Pfam Uncharacterised protein family UPF0047
VV1_1421	COG3706	GGDEF domain
VV1_1421	COG0745	RESPONSE REGULATOR receiver
VV1_1424	COG0527	aspartate kinase activity
VV1_1425	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VV1_1432	COG2199	diguanylate cyclase activity
VV1_1432	COG2200	EAL domain
VV1_1437	COG3267	Type II secretory pathway component ExeA
VV1_1437	COG3409	Peptidoglycan-binding domain 1 protein
VV1_1439	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VV1_1440	COG1459	type II secretion system
VV1_1449	COG1077	Cell shape determining protein MreB Mrl
VV1_1450	COG1792	Involved in formation and maintenance of cell shape
VV1_1451	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
VV1_1453	COG1530	ribonuclease E activity
VV1_1454	COG3164	Protein of unknown function
VV1_1455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VV1_1456	COG0312	modulator of DNA gyrase
VV1_1457	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
VV1_1462	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VV1_1463	COG0251	oxidation-reduction process
VV1_1470	COG0456	acetyltransferase
VV1_1472	COG4269	membrane
VV1_1475	COG2927	DNA polymerase III (CHI subunit)
VV1_1477	COG0795	lipopolysaccharide-transporting ATPase activity
VV1_1478	COG0795	lipopolysaccharide-transporting ATPase activity
VV1_1481	COG0726	polysaccharide deacetylase
VV1_1482	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VV1_1484	COG1447	Phosphotransferase system cellobiose-specific component IIA
VV1_1485	COG1486	melibiose metabolic process
VV1_1487	COG1609	Transcriptional regulator
VV1_1489	COG3437	response regulator, receiver
VV1_1513	COG0741	lytic transglycosylase activity
VV1_1519	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VV1_1523	COG0762	integral membrane protein
VV1_1524	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
VV1_1525	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
VV1_1531	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VV1_1533	COG2356	endonuclease I
VV1_1541	COG0191	fructose-bisphosphate aldolase activity
VV1_1542	COG0668	transmembrane transport
VV1_1543	COG1279	arginine transmembrane transporter activity
VV1_1546	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VV1_1548	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
VV1_1549	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
VV1_1552	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VV1_1553	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VV1_1558	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VV1_1559	COG1595	DNA-templated transcription, initiation
VV1_1562	COG3086	response to oxidative stress
VV1_1564	COG0681	Belongs to the peptidase S26 family
VV1_1572	COG5001	Diguanylate cyclase
VV1_1573	COG3437	response regulator, receiver
VV1_1573	COG3850	Histidine kinase
VV1_1573	COG4999	Histidine kinase
VV1_1573	COG2205	protein histidine kinase activity
VV1_1575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VV1_1577	COG3956	TIGRFAM MazG family protein
VV1_1587	COG4942	peptidase
VV1_1587	COG1388	LysM domain
VV1_1588	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VV1_1594	COG0527	aspartate kinase activity
VV1_1601	COG0511	ligase activity, forming carbon-carbon bonds
VV1_1601	COG5016	pyruvate
VV1_1602	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VV1_1604	COG1238	metal cluster binding
VV1_1605	COG0612	Peptidase, M16
VV1_1609	COG4536	flavin adenine dinucleotide binding
VV1_1610	COG4137	Cytochrome C assembly protein
VV1_1612	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VV1_1624	COG1459	type II secretion system
VV1_1625	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VV1_1628	COG3023	N-Acetylmuramoyl-L-alanine amidase
VV1_1629	COG2186	Transcriptional regulator
VV1_1630	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VV1_1631	COG0508	dehydrogenase complex catalyzes the overall conversion of
VV1_1632	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VV1_1637	COG0288	reversible hydration of carbon dioxide
VV1_1638	COG0659	secondary active sulfate transmembrane transporter activity
VV1_1640	COG1131	(ABC) transporter
VV1_1641	COG0842	Transport permease protein
VV1_1644	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VV1_1648	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
VV1_1650	COG1643	Atp-dependent helicase
VV1_1651	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VV1_1652	COG1752	Esterase of the alpha-beta hydrolase superfamily
VV1_1653	COG1049	propionate catabolic process, 2-methylcitrate cycle
VV1_1654	COG1929	Belongs to the glycerate kinase type-1 family
VV1_1655	COG2610	gluconate transmembrane transporter activity
VV1_1656	COG3835	regulator
VV1_1658	COG0347	Belongs to the P(II) protein family
VV1_1659	COG0004	ammonium transporteR
VV1_1660	COG1840	ABC-type Fe3 transport system, periplasmic component
VV1_1664	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VV1_1667	COG2971	BadF BadG BcrA BcrD
VV1_1669	COG4608	Belongs to the ABC transporter superfamily
VV1_1670	COG0444	Belongs to the ABC transporter superfamily
VV1_1671	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VV1_1672	COG0601	transmembrane transport
VV1_1674	COG0784	Response regulator, receiver
VV1_1674	COG2205	protein histidine kinase activity
VV1_1676	COG0628	permease
VV1_1682	COG0739	heme binding
VV1_1684	COG2832	Protein of unknown function (DUF454)
VV1_1685	COG2027	D-alanyl-D-alanine carboxypeptidase
VV1_1688	COG1534	Rna-binding protein
VV1_1690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VV1_1691	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
VV1_1693	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VV1_1695	COG0195	Participates in both transcription termination and antitermination
VV1_1699	COG3385	transposase activity
VV1_1709	COG4785	May be involved in cell division
VV1_1711	COG0534	Mate efflux family protein
VV1_1716	COG3153	acetyltransferase
VV1_1718	COG0456	acetyltransferase
VV1_1720	COG3706	GGDEF domain
VV1_1722	COG0084	hydrolase, TatD family'
VV1_1723	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VV1_1730	COG0560	Phosphoserine phosphatase
VV1_1732	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VV1_1737	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VV1_1740	COG0583	DNA-binding transcription factor activity
VV1_1742	COG1022	Amp-dependent synthetase and ligase
VV1_1749	COG4964	Belongs to the GSP D family
VV1_1759	COG2059	Chromate
VV1_1760	COG0583	DNA-binding transcription factor activity
VV1_1763	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
VV1_1763	COG3408	Glycogen debranching enzyme
VV1_1764	COG0531	amino acid
VV1_1765	COG0531	amino acid
VV1_1766	COG2731	YhcH YjgK YiaL family protein
VV1_1767	COG3250	beta-galactosidase activity
VV1_1769	COG1609	Transcriptional regulator
VV1_1770	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VV1_1773	COG2017	converts alpha-aldose to the beta-anomer
VV1_1774	COG0840	transmembrane signaling receptor activity
VV1_1777	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VV1_1782	COG0569	domain protein
VV1_1782	COG0189	ligase activity
VV1_1785	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VV1_1786	COG1349	DNA-binding transcription factor activity
VV1_1788	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VV1_1790	COG2171	N-acyltransferase activity
VV1_1791	COG3141	response to X-ray
VV1_1794	COG3083	sulfuric ester hydrolase activity
VV1_1795	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VV1_1796	COG1074	ATP-dependent DNA helicase activity
VV1_1797	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VV1_1801	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
VV1_1802	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VV1_1803	COG2166	iron-sulfur cluster assembly
VV1_1805	COG0840	transmembrane signaling receptor activity
VV1_1808	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VV1_1809	COG0693	protein deglycase activity
VV1_1810	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VV1_1811	COG3248	Nucleoside-binding outer membrane protein
VV1_1814	COG1595	DNA-templated transcription, initiation
VV1_1816	COG2211	Major facilitator Superfamily
VV1_1820	COG0271	Belongs to the BolA IbaG family
VV1_1827	COG1477	protein flavinylation
VV1_1829	COG0745	RESPONSE REGULATOR receiver
VV1_1829	COG3706	GGDEF domain
VV1_1831	COG0514	ATP-dependent DNA helicase (RecQ)
VV1_1834	COG0733	neurotransmitter:sodium symporter activity
VV1_1839	COG1720	tRNA m6t6A37 methyltransferase activity
VV1_1841	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VV1_1845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VV1_1854	COG3098	single-species biofilm formation
VV1_1858	COG0024	Methionine aminopeptidase
VV1_1862	COG0233	cytoplasmic translational termination
VV1_1865	COG0575	Belongs to the CDS family
VV1_1867	COG0750	zinc metalloprotease
VV1_1868	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VV1_1869	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
VV1_1875	COG0587	DNA-directed DNA polymerase activity
VV1_1879	COG0347	Belongs to the P(II) protein family
VV1_1882	COG0741	lytic transglycosylase activity
VV1_1882	COG1388	LysM domain
VV1_1883	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VV1_1884	COG2226	methyltransferase
VV1_1887	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VV1_1889	COG2249	NAD(P)H dehydrogenase (quinone) activity
VV1_1896	COG1960	acyl-CoA dehydrogenase activity
VV1_1898	COG0121	glutamine amidotransferase
VV1_1899	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VV1_1901	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VV1_1902	COG2233	PERMEase
VV1_1906	COG1393	Belongs to the ArsC family
VV1_1907	COG4783	chaperone-mediated protein folding
VV1_1910	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VV1_1911	COG2716	regulation of RNA biosynthetic process
VV1_1917	COG1393	Belongs to the ArsC family
VV1_1922	COG2837	iron assimilation
VV1_1923	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VV1_1924	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VV1_1926	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VV1_1927	COG1334	flagellar protein FlaG
VV1_1928	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VV1_1930	COG1516	flagellar protein fliS
VV1_1931	COG2204	response regulator
VV1_1932	COG4191	Histidine kinase
VV1_1933	COG2204	response regulator
VV1_1934	COG1677	Flagellar hook-basal body complex protein FliE
VV1_1936	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VV1_1946	COG1987	bacterial-type flagellum assembly
VV1_1947	COG1684	flagellar biosynthetic protein fliR
VV1_1951	COG0455	bacterial-type flagellum organization
VV1_1954	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
VV1_1955	COG0643	Histidine kinase
VV1_1955	COG2198	Histidine kinase
VV1_1957	COG1192	Involved in chromosome partitioning
VV1_1959	COG0835	chemotaxis
VV1_1962	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VV1_1963	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VV1_1964	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VV1_1966	COG1138	Cytochrome C-type biogenesis protein
VV1_1967	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VV1_1968	COG3088	subunit of a heme lyase
VV1_1968	COG4235	cytochrome complex assembly
VV1_1970	COG2853	Lipoprotein
VV1_1972	COG2067	long-chain fatty acid transport protein
VV1_1977	COG1025	Belongs to the peptidase M16 family
VV1_1978	COG2062	phosphohistidine phosphatase, SixA
VV1_1980	COG2890	protein-(glutamine-N5) methyltransferase activity
VV1_1982	COG2860	membrane
VV1_1983	COG3101	peptidyl-lysine hydroxylation
VV1_1986	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VV1_1989	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VV1_1994	COG0285	dihydrofolate synthase activity
VV1_1995	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
VV1_1996	COG1286	toxin biosynthetic process
VV1_1997	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VV1_1998	COG0583	DNA-binding transcription factor activity
VV1_1999	COG0745	RESPONSE REGULATOR receiver
VV1_2008	COG2205	protein histidine kinase activity
VV1_2009	COG0745	RESPONSE REGULATOR receiver
VV1_2016	COG0346	lactoylglutathione lyase activity
VV1_2018	COG1785	Belongs to the alkaline phosphatase family
VV1_2021	COG2226	methyltransferase
VV1_2046	COG1396	sequence-specific DNA binding
VV1_2047	COG3550	peptidyl-serine autophosphorylation
VV1_2052	COG2239	Acts as a magnesium transporter
VV1_2053	COG2199	diguanylate cyclase activity
VV1_2053	COG2203	Gaf domain
VV1_2058	COG3710	Transcriptional regulator
VV1_2059	COG0531	amino acid
VV1_2060	COG1982	Orn Lys Arg decarboxylase major
VV1_2061	COG3706	GGDEF domain
VV1_2062	COG4109	DRTGG domain
VV1_2067	COG0537	adenosine 5'-monophosphoramidase activity
VV1_2074	COG1252	NADH dehydrogenase
VV1_2078	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
VV1_2080	COG4591	ABC-type transport system involved in lipoprotein release permease component
VV1_2082	COG4591	ABC-type transport system involved in lipoprotein release permease component
VV1_2084	COG0658	competence protein
VV1_2084	COG2333	competence protein COMEC
VV1_2089	COG2199	diguanylate cyclase activity
VV1_2090	COG2719	SpoVR family
VV1_2092	COG2766	serine protein kinase
VV1_2095	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VV1_2098	COG1882	Formate acetyltransferase
VV1_2103	COG4215	(ABC) transporter
VV1_2106	COG0708	Exodeoxyribonuclease III
VV1_2107	COG0840	transmembrane signaling receptor activity
VV1_2111	COG3923	Primosomal replication protein n
VV1_2113	COG1199	ATP-dependent helicase activity
VV1_2114	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VV1_2119	COG1278	Cold shock
VV1_2121	COG0542	response to heat
VV1_2123	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VV1_2127	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
VV1_2130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VV1_2136	COG3070	regulator of competence-specific genes
VV1_2140	COG0745	RESPONSE REGULATOR receiver
VV1_2141	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VV1_2142	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VV1_2152	COG4067	protein conserved in archaea
VV1_2152	COG0189	ligase activity
VV1_2158	COG0840	transmembrane signaling receptor activity
VV1_2160	COG2255	four-way junction helicase activity
VV1_2162	COG1271	oxidase subunit
VV1_2163	COG1294	oxidase, subunit
VV1_2164	COG4890	Cyd operon protein YbgT
VV1_2166	COG0824	Thioesterase
VV1_2167	COG0811	peptide transport
VV1_2171	COG2885	chlorophyll binding
VV1_2172	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
VV1_2175	COG3766	membrane
VV1_2177	COG0754	glutathionylspermidine amidase activity
VV1_2179	COG0784	Response regulator, receiver
VV1_2179	COG2205	protein histidine kinase activity
VV1_2195	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
VV1_2198	COG0546	phosphoglycolate phosphatase activity
VV1_2199	COG0840	transmembrane signaling receptor activity
VV1_2200	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VV1_2201	COG0861	Integral membrane protein TerC family
VV1_2208	COG2207	Transcriptional regulator
VV1_2218	COG0583	DNA-binding transcription factor activity
VV1_2220	COG0857	belongs to the CobB CobQ family
VV1_2220	COG0280	phosphate acetyltransferase
VV1_2222	COG3092	negative regulation of chromosome organization
VV1_2225	COG4120	Belongs to the binding-protein-dependent transport system permease family
VV1_2227	COG0366	Alpha amylase catalytic
VV1_2228	COG3706	GGDEF domain
VV1_2228	COG0745	RESPONSE REGULATOR receiver
VV1_2230	COG0653	protein targeting
VV1_2237	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VV1_2242	COG1846	Transcriptional regulator
VV1_2243	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VV1_2244	COG0840	transmembrane signaling receptor activity
VV1_2248	COG1448	Aminotransferase
VV1_2249	COG2770	Histidine kinase
VV1_2249	COG3437	response regulator, receiver
VV1_2252	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VV1_2255	COG0840	transmembrane signaling receptor activity
VV1_2257	COG0720	synthase
VV1_2259	COG2200	EAL domain
VV1_2260	COG1760	l-serine dehydratase
VV1_2261	COG0814	amino acid
VV1_2262	COG0494	nUDIX hydrolase
VV1_2265	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VV1_2268	COG3106	COG3106 Predicted ATPase
VV1_2269	COG3768	UPF0283 membrane protein
VV1_2270	COG3283	Transcriptional regulator of aromatic amino acids metabolism
VV1_2271	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VV1_2274	COG0471	metal ion transport
VV1_2275	COG4191	Histidine kinase
VV1_2275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VV1_2277	COG3706	GGDEF domain
VV1_2278	COG2199	diguanylate cyclase activity
VV1_2278	COG2200	EAL domain
VV1_2281	COG3300	MHYT domain
VV1_2281	COG5001	Diguanylate cyclase
VV1_2282	COG1328	CTP reductase activity
VV1_2283	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VV1_2284	COG0583	DNA-binding transcription factor activity
VV1_2288	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VV1_2289	COG4667	esterase of the alpha-beta hydrolase superfamily
VV1_2292	COG1597	lipid kinase activity
VV1_2293	COG0814	amino acid
VV1_2296	COG0783	Belongs to the Dps family
VV1_2299	COG1132	(ABC) transporter
VV1_2300	COG1132	(ABC) transporter
VV1_2301	COG1115	amino acid carrier protein
VV1_2304	COG1596	polysaccharide export
VV1_2309	COG0438	transferase activity, transferring glycosyl groups
VV1_2310	COG0438	transferase activity, transferring glycosyl groups
VV1_2310	COG0297	glycogen (starch) synthase activity
VV1_2318	COG0443	Heat shock 70 kDa protein
VV1_2319	COG0443	Heat shock 70 kDa protein
VV1_2321	COG3706	GGDEF domain
VV1_2325	COG3713	MltA-interacting MipA family protein
VV1_2331	COG4964	Belongs to the GSP D family
VV1_2333	COG2894	cell division
VV1_2343	COG1643	Atp-dependent helicase
VV1_2349	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
VV1_2351	COG2814	Major facilitator Superfamily
VV1_2354	COG0840	transmembrane signaling receptor activity
VV1_2355	COG0010	Belongs to the arginase family
VV1_2369	COG0745	RESPONSE REGULATOR receiver
VV1_2369	COG3706	GGDEF domain
VV1_2382	COG2885	chlorophyll binding
VV1_2385	COG0277	FAD linked oxidase domain protein
VV1_2385	COG0247	lactate metabolic process
VV1_2386	COG2020	methyltransferase activity
VV1_2387	COG5640	endopeptidase activity
VV1_2395	COG4326	sporulation control protein
VV1_2415	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VV1_2415	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VV1_2431	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VV1_2450	COG1715	Restriction endonuclease
VV1_2462	COG0582	viral genome integration into host DNA
VV1_2475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VV1_2487	COG0791	NLP P60 protein
VV1_2496	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VV1_2509	COG1280	lysine exporter protein (LysE YggA)
VV1_2511	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VV1_2524	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VV1_2534	COG1942	4-Oxalocrotonate Tautomerase
VV1_2540	COG0456	acetyltransferase
VV1_2551	COG2801	Transposase and inactivated derivatives
VV1_2560	COG0307	riboflavin synthase, alpha
VV1_2564	COG3706	GGDEF domain
VV1_2566	COG0791	NLP P60 protein
VV1_2567	COG0840	transmembrane signaling receptor activity
VV1_2567	COG3290	protein histidine kinase activity
VV1_2574	COG3842	ATPase activity
VV1_2575	COG4662	Binding-protein-dependent transport system inner membrane component
VV1_2577	COG2204	response regulator
VV1_2578	COG3852	Histidine kinase
VV1_2581	COG0488	(ABC) transporter
VV1_2584	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VV1_2590	COG3383	formate dehydrogenase (NAD+) activity
VV1_2590	COG0243	molybdopterin cofactor binding
VV1_2591	COG0437	4 iron, 4 sulfur cluster binding
VV1_2598	COG0004	ammonium transporteR
VV1_2600	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VV1_2601	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VV1_2602	COG1177	transmembrane transport
VV1_2603	COG1176	ABC-type spermidine putrescine transport system, permease component I
VV1_2606	COG2992	FlgJ-related protein
VV1_2609	COG0589	response to stress
VV1_2610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VV1_2614	COG2217	Heavy metal translocating P-type atpase
VV1_2617	COG2010	Cytochrome c
VV1_2620	COG3278	Belongs to the heme-copper respiratory oxidase family
VV1_2628	COG1067	ATP-dependent peptidase activity
VV1_2635	COG0116	Belongs to the methyltransferase superfamily
VV1_2635	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VV1_2639	COG2902	Dehydrogenase
VV1_2641	COG0308	aminopeptidase N
VV1_2645	COG1956	GAF domain-containing protein
VV1_2646	COG1132	(ABC) transporter
VV1_2647	COG2995	paraquat-inducible protein a
VV1_2648	COG3008	intermembrane lipid transfer
VV1_2650	COG2996	Protein conserved in bacteria
VV1_2654	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VV1_2656	COG3706	GGDEF domain
VV1_2657	COG1793	dna ligase
VV1_2658	COG1366	Belongs to the anti-sigma-factor antagonist family
VV1_2664	COG2204	response regulator
VV1_2673	COG0438	transferase activity, transferring glycosyl groups
VV1_2675	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VV1_2682	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
VV1_2683	COG0363	glucosamine-6-phosphate deaminase activity
VV1_2684	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VV1_2685	COG4565	transcriptional regulatory protein
VV1_2686	COG3290	protein histidine kinase activity
VV1_2689	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VV1_2695	COG1115	amino acid carrier protein
VV1_2698	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VV1_2699	COG0204	Acyl-transferase
VV1_2700	COG0348	domain, Protein
VV1_2701	COG0437	4 iron, 4 sulfur cluster binding
VV1_2703	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VV1_2704	COG4597	amino acid ABC transporter
VV1_2705	COG0765	amino acid transport
VV1_2706	COG1126	abc transporter atp-binding protein
VV1_2707	COG0670	Belongs to the BI1 family
VV1_2710	COG2920	part of a sulfur-relay system
VV1_2714	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VV1_2719	COG3706	GGDEF domain
VV1_2721	COG0602	queuosine metabolic process
VV1_2722	COG0561	phosphatase activity
VV1_2729	COG2828	Protein conserved in bacteria
VV1_2730	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
VV1_2731	COG0372	Belongs to the citrate synthase family
VV1_2732	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
VV1_2734	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VV1_2744	COG2197	response regulator
VV1_2746	COG0730	response to heat
VV1_2749	COG1653	transport
VV1_2750	COG1175	transmembrane transport
VV1_2751	COG0395	ABC-type sugar transport system, permease component
VV1_2753	COG1349	DNA-binding transcription factor activity
VV1_2754	COG0584	glycerophosphoryl diester phosphodiesterase
VV1_2757	COG1278	Cold shock
VV1_2759	COG3706	GGDEF domain
VV1_2759	COG0745	RESPONSE REGULATOR receiver
VV1_2765	COG0625	glutathione transferase activity
VV1_2767	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
VV1_2769	COG2195	Cleaves the N-terminal amino acid of tripeptides
VV1_2773	COG3063	Type IV pilus biogenesis stability protein PilW
VV1_2775	COG1451	nucleotide metabolic process
VV1_2792	COG2925	Exonuclease
VV1_2793	COG1380	Effector of murein hydrolase LrgA
VV1_2794	COG1346	cytolysis
VV1_2800	COG1643	Atp-dependent helicase
VV1_2801	COG0281	malic enzyme
VV1_2802	COG2949	membrane
VV1_2805	COG0471	metal ion transport
VV1_2806	COG3706	GGDEF domain
VV1_2806	COG0745	RESPONSE REGULATOR receiver
VV1_2808	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VV1_2810	COG0492	ferredoxin-NADP+ reductase activity
VV1_2811	COG4988	ABC transporter
VV1_2812	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
VV1_2815	COG5002	protein histidine kinase activity
VV1_2815	COG5002	protein histidine kinase activity
VV1_2820	COG3070	regulator of competence-specific genes
VV1_2822	COG2431	L-lysine efflux transmembrane transporter activity
VV1_2824	COG0076	glutamate decarboxylase activity
VV1_2825	COG1737	Transcriptional regulator
VV1_2826	COG1979	alcohol dehydrogenase
VV1_2827	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VV1_2828	COG2985	domain, Protein
VV1_2828	COG3273	potassium ion transport
VV1_2838	COG1136	(ABC) transporter
VV1_2839	COG0702	epimerase
VV1_2842	COG2814	Major facilitator Superfamily
VV1_2845	COG1061	Type III restriction enzyme res subunit
VV1_2848	COG2205	protein histidine kinase activity
VV1_2857	COG3313	Fe-S protein
VV1_2859	COG4134	Bacterial extracellular solute-binding protein
VV1_2860	COG4135	transport system, permease component
VV1_2861	COG4136	ATPase activity
VV1_2862	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VV1_2863	COG3604	Transcriptional regulator
VV1_2865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VV1_2867	COG0564	pseudouridine synthase activity
VV1_2869	COG0733	neurotransmitter:sodium symporter activity
VV1_2872	COG0626	cystathionine gamma-synthase activity
VV1_2873	COG2818	Glycosylase
VV1_2875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VV1_2877	COG1983	PspC domain protein
VV1_2879	COG1842	Phage shock protein A
VV1_2880	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
VV1_2882	COG4168	peptide transport system, permease
VV1_2883	COG4171	peptide transport system, permease
VV1_2885	COG4172	Belongs to the ABC transporter superfamily
VV1_2888	COG1227	inorganic diphosphatase activity
VV1_2896	COG3005	denitrification pathway
VV1_2897	COG4459	periplasmic nitrate reductase
VV1_2898	COG0390	transport system, permease component
VV1_2900	COG2116	formate transmembrane transporter activity
VV1_2904	COG0583	DNA-binding transcription factor activity
VV1_2905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VV1_2909	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VV1_2911	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VV1_2916	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VV1_2922	COG1757	Na H antiporter
VV1_2923	COG2916	Histone family protein nucleoid-structuring protein H-NS
VV1_2924	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VV1_2928	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VV1_2932	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VV1_2935	COG1028	Short-chain dehydrogenase reductase Sdr
VV1_2938	COG0501	Belongs to the peptidase M48B family
VV1_2947	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VV1_2952	COG0686	Belongs to the AlaDH PNT family
VV1_2954	COG0583	DNA-binding transcription factor activity
VV1_2959	COG3385	transposase activity
VV1_2962	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VV1_2963	COG3108	Peptidase M15
VV1_2964	COG2989	Protein conserved in bacteria
VV1_2972	COG4608	Belongs to the ABC transporter superfamily
VV1_2973	COG0444	Belongs to the ABC transporter superfamily
VV1_2974	COG4166	transmembrane transport
VV1_2975	COG4239	(ABC) transporter, permease
VV1_2976	COG4174	ABC transporter (Permease)
VV1_2978	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VV1_2979	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
VV1_2982	COG0539	negative regulation of cytoplasmic translation
VV1_2985	COG0616	signal peptide processing
VV1_2986	COG1028	Short-chain dehydrogenase reductase Sdr
VV1_2990	COG0784	Response regulator, receiver
VV1_2990	COG0835	chemotaxis
VV1_2991	COG1940	carbohydrate kinase activity
VV1_2992	COG0469	pyruvate kinase activity
VV1_2993	COG4667	esterase of the alpha-beta hydrolase superfamily
VV1_2996	COG0733	neurotransmitter:sodium symporter activity
VV1_2999	COG1263	PTS System
VV1_2999	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VV1_3000	COG0084	hydrolase, TatD family'
VV1_3004	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VV1_3014	COG1399	metal-binding, possibly nucleic acid-binding protein
VV1_3018	COG1530	ribonuclease E activity
VV1_3020	COG0659	secondary active sulfate transmembrane transporter activity
VV1_3021	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VV1_3022	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
VV1_3027	COG0489	protein tyrosine kinase activity
VV1_3030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VV1_3031	COG1138	Cytochrome C-type biogenesis protein
VV1_3032	COG3301	Polysulphide reductase, NrfD
VV1_3033	COG0437	4 iron, 4 sulfur cluster binding
VV1_3034	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
VV1_3041	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VV1_3042	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VV1_3054	COG2197	response regulator
VV1_3055	COG0417	DNA replication proofreading
VV1_3056	COG5001	Diguanylate cyclase
VV1_3062	COG0009	L-threonylcarbamoyladenylate synthase
VV1_3063	COG0613	PHP domain protein
VV1_3064	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VV1_3065	COG0512	Glutamine amidotransferase of anthranilate synthase
VV1_3067	COG0135	phosphoribosylanthranilate isomerase activity
VV1_3067	COG0134	indole-3-glycerol-phosphate synthase activity
VV1_3070	COG1301	dicarboxylic acid transport
VV1_3074	COG1607	acyl-coa hydrolase
VV1_3075	COG2350	Protein conserved in bacteria
VV1_3077	COG0435	Glutathione S-transferase
VV1_3079	COG0444	Belongs to the ABC transporter superfamily
VV1_3080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VV1_3081	COG0601	transmembrane transport
VV1_3084	COG0314	molybdopterin synthase activity
VV1_3085	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VV1_3087	COG0521	Mo-molybdopterin cofactor biosynthetic process
VV1_3089	COG0391	Required for morphogenesis under gluconeogenic growth conditions
VV1_3095	COG4656	Part of a membrane complex involved in electron transport
VV1_3097	COG4659	FMN binding
VV1_3099	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VV1_3100	COG0346	lactoylglutathione lyase activity
VV1_3102	COG2885	chlorophyll binding
VV1_3104	COG2056	Na+-H+ antiporter family
VV1_3106	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VV1_3109	COG1028	Short-chain dehydrogenase reductase Sdr
VV1_3111	COG1012	belongs to the aldehyde dehydrogenase family
VV1_3111	COG1454	alcohol dehydrogenase
VV1_3112	COG2095	MarC family integral membrane protein
VV1_3113	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VV1_3115	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VV1_3117	COG1757	Na H antiporter
VV1_3120	COG3081	Nucleoid-associated protein
VV1_3122	COG3083	sulfuric ester hydrolase activity
VV1_3123	COG0569	domain protein
VV1_3124	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VV1_3125	COG2731	YhcH YjgK YiaL family protein
VV1_3126	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VV1_3127	COG3706	GGDEF domain
VV1_3127	COG0745	RESPONSE REGULATOR receiver
VV1_3129	COG0123	including yeast histone deacetylase and acetoin utilization protein
VV1_3130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VV1_3131	COG0778	Nitroreductase
VV1_3132	COG0446	pyridine nucleotide-disulphide oxidoreductase
VV1_3132	COG1902	pentaerythritol trinitrate reductase activity
VV1_3133	COG0616	signal peptide processing
VV1_3135	COG0252	asparaginase activity
VV1_3136	COG3139	Protein of unknown function (DUF1315)
VV1_3140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VV1_3146	COG5001	Diguanylate cyclase
VV1_3149	COG3126	Type III secretion system lipoprotein chaperone (YscW)
VV1_3150	COG1946	Acyl-CoA thioesterase
VV1_3152	COG1522	sequence-specific DNA binding
VV1_3153	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VV1_3156	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VV1_3157	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VV1_3168	COG0318	PFAM AMP-dependent synthetase and ligase
VV1_3169	COG1441	menaquinone biosynthetic process
VV1_3170	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
VV1_3171	COG0596	Alpha beta hydrolase
VV1_3173	COG1169	isochorismate synthase
VV1_3174	COG0436	Aminotransferase
VV1_3175	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
VV1_3194	COG3547	Transposase (IS116 IS110 IS902 family)
VV1_3195	COG1566	PFAM secretion protein HlyD family protein
VV1_3197	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VV1_3202	COG0784	Response regulator, receiver
VV1_3202	COG2205	protein histidine kinase activity
VV1_3208	COG1672	PFAM Archaeal ATPase
VV1_3208	COG2319	Wd-40 repeat
VV1_3252	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
VV2_0002	COG4175	Glycine betaine
VV2_0003	COG3059	membrane
VV2_0004	COG3385	transposase activity
VV2_0010	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VV2_0012	COG0247	lactate metabolic process
VV2_0013	COG0546	phosphoglycolate phosphatase activity
VV2_0015	COG1619	proteins homologs of microcin C7 resistance protein MccF
VV2_0016	COG2133	pyrroloquinoline quinone binding
VV2_0019	COG1454	alcohol dehydrogenase
VV2_0020	COG0443	Heat shock 70 kDa protein
VV2_0022	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VV2_0029	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VV2_0031	COG3174	membrane
VV2_0037	COG0814	amino acid
VV2_0038	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
VV2_0045	COG2962	Rard protein
VV2_0048	COG0671	phosphoesterase, PA-phosphatase related
VV2_0050	COG1288	antiporter activity
VV2_0053	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
VV2_0057	COG2315	Protein conserved in bacteria
VV2_0063	COG1172	Belongs to the binding-protein-dependent transport system permease family
VV2_0064	COG1879	ABC-type sugar transport system periplasmic component
VV2_0065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VV2_0066	COG1609	Transcriptional regulator
VV2_0068	COG0835	chemotaxis
VV2_0068	COG0784	Response regulator, receiver
VV2_0070	COG0456	acetyltransferase
VV2_0073	COG1366	Belongs to the anti-sigma-factor antagonist family
VV2_0075	COG2172	sigma factor antagonist activity
VV2_0078	COG3437	response regulator, receiver
VV2_0079	COG0420	3'-5' exonuclease activity
VV2_0080	COG0419	ATPase involved in DNA repair
VV2_0083	COG0583	DNA-binding transcription factor activity
VV2_0086	COG4964	Belongs to the GSP D family
VV2_0102	COG0471	metal ion transport
VV2_0103	COG3290	protein histidine kinase activity
VV2_0105	COG0110	maltose O-acetyltransferase activity
VV2_0110	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VV2_0111	COG4605	iron ion homeostasis
VV2_0112	COG4604	ABC transporter, ATP-binding protein
VV2_0113	COG0789	Transcriptional regulator
VV2_0121	COG1289	transmembrane transporter activity
VV2_0122	COG0210	DNA helicase
VV2_0124	COG1879	ABC-type sugar transport system periplasmic component
VV2_0125	COG0784	Response regulator, receiver
VV2_0125	COG2205	protein histidine kinase activity
VV2_0125	COG2198	Histidine kinase
VV2_0130	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VV2_0131	COG3005	denitrification pathway
VV2_0136	COG0513	Belongs to the DEAD box helicase family
VV2_0138	COG5001	Diguanylate cyclase
VV2_0138	COG1716	ATPase activity
VV2_0143	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VV2_0147	COG0513	Belongs to the DEAD box helicase family
VV2_0149	COG3119	arylsulfatase activity
VV2_0151	COG3119	arylsulfatase activity
VV2_0152	COG0641	radical SAM
VV2_0154	COG0714	Associated with various cellular activities
VV2_0161	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
VV2_0163	COG0641	radical SAM
VV2_0168	COG3385	transposase activity
VV2_0169	COG2814	Major facilitator Superfamily
VV2_0173	COG0583	DNA-binding transcription factor activity
VV2_0174	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
VV2_0177	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VV2_0177	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
VV2_0179	COG1132	(ABC) transporter
VV2_0198	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
VV2_0198	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VV2_0198	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VV2_0199	COG1105	Belongs to the carbohydrate kinase PfkB family
VV2_0200	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VV2_0200	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VV2_0201	COG1609	Transcriptional regulator
VV2_0206	COG0469	pyruvate kinase activity
VV2_0207	COG2271	Major facilitator Superfamily
VV2_0208	COG1840	ABC-type Fe3 transport system, periplasmic component
VV2_0209	COG4191	Histidine kinase
VV2_0211	COG1979	alcohol dehydrogenase
VV2_0212	COG2207	Transcriptional regulator
VV2_0218	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VV2_0221	COG0784	Response regulator, receiver
VV2_0221	COG3437	response regulator, receiver
VV2_0222	COG0546	phosphoglycolate phosphatase activity
VV2_0224	COG0840	transmembrane signaling receptor activity
VV2_0227	COG0513	Belongs to the DEAD box helicase family
VV2_0230	COG3038	cytochrome b561
VV2_0232	COG2116	formate transmembrane transporter activity
VV2_0234	COG0583	DNA-binding transcription factor activity
VV2_0236	COG3593	DNA synthesis involved in DNA repair
VV2_0237	COG0737	Belongs to the 5'-nucleotidase family
VV2_0239	COG0861	Integral membrane protein TerC family
VV2_0248	COG2267	carboxylic ester hydrolase activity
VV2_0249	COG2067	long-chain fatty acid transport protein
VV2_0252	COG2050	protein possibly involved in aromatic compounds catabolism
VV2_0254	COG4533	DNA binding
VV2_0256	COG0366	Alpha amylase catalytic
VV2_0257	COG0583	DNA-binding transcription factor activity
VV2_0261	COG0484	heat shock protein binding
VV2_0264	COG5001	Diguanylate cyclase
VV2_0264	COG1716	ATPase activity
VV2_0267	COG4181	ATPase activity
VV2_0268	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
VV2_0270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VV2_0270	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
VV2_0271	COG1984	allophanate hydrolase subunit 2
VV2_0272	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
VV2_0275	COG3447	MASE1 domain protein
VV2_0275	COG5001	Diguanylate cyclase
VV2_0275	COG5002	protein histidine kinase activity
VV2_0277	COG0583	DNA-binding transcription factor activity
VV2_0278	COG1042	CoA-binding domain protein
VV2_0278	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VV2_0278	COG0045	succinate-CoA ligase (ADP-forming) activity
VV2_0282	COG0023	Translation Initiation Factor
VV2_0313	COG0745	RESPONSE REGULATOR receiver
VV2_0316	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
VV2_0317	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
VV2_0320	COG3706	GGDEF domain
VV2_0322	COG0745	RESPONSE REGULATOR receiver
VV2_0325	COG1846	Transcriptional regulator
VV2_0326	COG0697	spore germination
VV2_0328	COG4149	molybdate abc transporter
VV2_0329	COG0725	ABC transporter, periplasmic molybdate-binding protein
VV2_0333	COG4067	protein conserved in archaea
VV2_0333	COG0189	ligase activity
VV2_0336	COG0602	queuosine metabolic process
VV2_0337	COG1328	CTP reductase activity
VV2_0350	COG3118	belongs to the thioredoxin family
VV2_0351	COG0477	Major facilitator Superfamily
VV2_0353	COG0534	Mate efflux family protein
VV2_0358	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VV2_0361	COG0848	biopolymer transport protein
VV2_0362	COG0811	peptide transport
VV2_0363	COG0811	peptide transport
VV2_0369	COG2146	nitrite reductase [NAD(P)H] activity
VV2_0370	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VV2_0372	COG0840	transmembrane signaling receptor activity
VV2_0377	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VV2_0379	COG3706	GGDEF domain
VV2_0379	COG5001	Diguanylate cyclase
VV2_0379	COG4251	negative regulation of phosphorylation
VV2_0379	COG2203	Gaf domain
VV2_0381	COG0010	Belongs to the arginase family
VV2_0382	COG0513	Belongs to the DEAD box helicase family
VV2_0385	COG0523	cobalamin synthesis protein
VV2_0387	COG2199	diguanylate cyclase activity
VV2_0390	COG2146	nitrite reductase [NAD(P)H] activity
VV2_0390	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VV2_0391	COG1116	anion transmembrane transporter activity
VV2_0392	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
VV2_0393	COG1116	anion transmembrane transporter activity
VV2_0393	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
VV2_0394	COG3707	response regulator
VV2_0397	COG1648	precorrin-2 dehydrogenase activity
VV2_0397	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VV2_0398	COG0243	molybdopterin cofactor binding
VV2_0399	COG0456	acetyltransferase
VV2_0400	COG0366	Alpha amylase catalytic
VV2_0401	COG0840	transmembrane signaling receptor activity
VV2_0402	COG0840	transmembrane signaling receptor activity
VV2_0405	COG2271	Major facilitator Superfamily
VV2_0407	COG0584	glycerophosphoryl diester phosphodiesterase
VV2_0408	COG0312	modulator of DNA gyrase
VV2_0409	COG0312	modulator of DNA gyrase
VV2_0411	COG3069	C4-dicarboxylate transmembrane transporter activity
VV2_0412	COG1704	LemA family
VV2_0413	COG0501	Belongs to the peptidase M48B family
VV2_0415	COG3209	COG3209 Rhs family protein
VV2_0416	COG5444	nuclease activity
VV2_0425	COG3209	COG3209 Rhs family protein
VV2_0428	COG3501	Rhs element vgr protein
VV2_0439	COG0631	protein serine/threonine phosphatase activity
VV2_0446	COG2815	serine threonine protein kinase
VV2_0446	COG0515	serine threonine protein kinase
VV2_0450	COG3530	Putative quorum-sensing-regulated virulence factor
VV2_0455	COG3186	Phenylalanine-4-hydroxylase
VV2_0456	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VV2_0462	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
VV2_0464	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VV2_0464	COG4191	Histidine kinase
VV2_0465	COG3437	response regulator, receiver
VV2_0465	COG0784	Response regulator, receiver
VV2_0479	COG3064	Membrane
VV2_0479	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
VV2_0479	COG1073	alpha beta
VV2_0480	COG2994	toxin metabolic process
VV2_0488	COG1028	Short-chain dehydrogenase reductase Sdr
VV2_0490	COG1024	Enoyl-CoA hydratase
VV2_0491	COG1024	Enoyl-CoA hydratase
VV2_0492	COG1960	acyl-CoA dehydrogenase activity
VV2_0494	COG0183	Belongs to the thiolase family
VV2_0496	COG1960	acyl-CoA dehydrogenase activity
VV2_0497	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
VV2_0498	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
VV2_0501	COG0450	alkyl hydroperoxide reductase
VV2_0503	COG1278	Cold shock
VV2_0506	COG1309	transcriptional regulator
VV2_0507	COG2130	NADP-dependent
VV2_0511	COG2197	response regulator
VV2_0512	COG3851	Histidine kinase
VV2_0513	COG2271	Major facilitator Superfamily
VV2_0515	COG1482	cell wall glycoprotein biosynthetic process
VV2_0516	COG2203	Gaf domain
VV2_0516	COG2199	diguanylate cyclase activity
VV2_0518	COG3036	rescue of stalled ribosome
VV2_0519	COG1278	Cold shock
VV2_0526	COG0545	Peptidyl-prolyl cis-trans isomerase
VV2_0527	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VV2_0532	COG2195	Cleaves the N-terminal amino acid of tripeptides
VV2_0534	COG4989	oxidoreductase activity
VV2_0542	COG1914	H( )-stimulated, divalent metal cation uptake system
VV2_0544	COG0303	'Molybdopterin
VV2_0545	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VV2_0547	COG2897	thiosulfate sulfurtransferase activity
VV2_0557	COG0840	transmembrane signaling receptor activity
VV2_0558	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VV2_0559	COG2885	chlorophyll binding
VV2_0561	COG1612	heme a metabolic process
VV2_0566	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
VV2_0567	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
VV2_0568	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
VV2_0569	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VV2_0571	COG1280	lysine exporter protein (LysE YggA)
VV2_0576	COG1846	Transcriptional regulator
VV2_0577	COG1764	response to oxidative stress
VV2_0579	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VV2_0582	COG0697	spore germination
VV2_0586	COG2814	Major facilitator Superfamily
VV2_0587	COG0583	DNA-binding transcription factor activity
VV2_0588	COG4251	negative regulation of phosphorylation
VV2_0588	COG5001	Diguanylate cyclase
VV2_0588	COG3706	GGDEF domain
VV2_0588	COG2203	Gaf domain
VV2_0589	COG0251	oxidation-reduction process
VV2_0592	COG4145	pantothenate transmembrane transporter activity
VV2_0594	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
VV2_0596	COG1737	Transcriptional regulator
VV2_0596	COG0837	glucose binding
VV2_0598	COG1131	(ABC) transporter
VV2_0599	COG0842	Transport permease protein
VV2_0605	COG1846	Transcriptional regulator
VV2_0608	COG0513	Belongs to the DEAD box helicase family
VV2_0613	COG3568	Endonuclease Exonuclease Phosphatase
VV2_0616	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VV2_0658	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VV2_0661	COG2356	endonuclease I
VV2_0670	COG0330	HflC and HflK could
VV2_0675	COG3457	Alanine racemase
VV2_0682	COG2801	Transposase and inactivated derivatives
VV2_0683	COG3604	Transcriptional regulator
VV2_0685	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
VV2_0687	COG4208	sulfate ABC transporter
VV2_0694	COG0628	permease
VV2_0702	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VV2_0704	COG1566	PFAM secretion protein HlyD family protein
VV2_0711	COG0582	viral genome integration into host DNA
VV2_0714	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
VV2_0714	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
VV2_0716	COG0745	RESPONSE REGULATOR receiver
VV2_0718	COG2197	response regulator
VV2_0719	COG3850	Histidine kinase
VV2_0722	COG3043	anaerobic respiration
VV2_0723	COG3005	denitrification pathway
VV2_0726	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
VV2_0729	COG1737	Transcriptional regulator
VV2_0730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VV2_0731	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VV2_0732	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VV2_0733	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VV2_0736	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VV2_0741	COG0183	Belongs to the thiolase family
VV2_0743	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VV2_0745	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VV2_0755	COG2827	Endonuclease containing a URI domain
VV2_0761	COG5002	protein histidine kinase activity
VV2_0761	COG2205	protein histidine kinase activity
VV2_0761	COG0784	Response regulator, receiver
VV2_0767	COG0583	DNA-binding transcription factor activity
VV2_0773	COG1522	sequence-specific DNA binding
VV2_0774	COG0531	amino acid
VV2_0775	COG0121	glutamine amidotransferase
VV2_0778	COG2205	protein histidine kinase activity
VV2_0779	COG0745	RESPONSE REGULATOR receiver
VV2_0785	COG2239	Acts as a magnesium transporter
VV2_0788	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
VV2_0789	COG0402	S-adenosylhomocysteine deaminase activity
VV2_0792	COG1067	ATP-dependent peptidase activity
VV2_0794	COG4172	Belongs to the ABC transporter superfamily
VV2_0795	COG1505	serine-type exopeptidase activity
VV2_0796	COG0583	DNA-binding transcription factor activity
VV2_0797	COG1620	l-lactate permease
VV2_0799	COG1139	Iron-sulfur cluster binding protein
VV2_0804	COG2814	Major facilitator Superfamily
VV2_0811	COG5001	Diguanylate cyclase
VV2_0814	COG3015	lipoprotein NlpE involved in copper resistance
VV2_0815	COG1126	abc transporter atp-binding protein
VV2_0816	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VV2_0817	COG4215	(ABC) transporter
VV2_0818	COG4160	amino acid transport
VV2_0821	COG5001	Diguanylate cyclase
VV2_0821	COG5002	protein histidine kinase activity
VV2_0822	COG2755	lipolytic protein G-D-S-L family
VV2_0825	COG0840	transmembrane signaling receptor activity
VV2_0826	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VV2_0829	COG2977	Belongs to the P-Pant transferase superfamily
VV2_0833	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VV2_0834	COG1028	Short-chain dehydrogenase reductase Sdr
VV2_0835	COG1169	isochorismate synthase
VV2_0836	COG1021	2,3-dihydroxybenzoate-AMP ligase
VV2_0840	COG1021	2,3-dihydroxybenzoate-AMP ligase
VV2_0842	COG4607	ABC-type enterochelin transport system periplasmic component
VV2_0843	COG1629	transport
VV2_0843	COG4774	siderophore transport
VV2_0847	COG0189	ligase activity
VV2_0847	COG4067	protein conserved in archaea
VV2_0852	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VV2_0855	COG0814	amino acid
VV2_0856	COG0488	(ABC) transporter
VV2_0859	COG1609	Transcriptional regulator
VV2_0860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VV2_0867	COG1253	flavin adenine dinucleotide binding
VV2_0869	COG1012	belongs to the aldehyde dehydrogenase family
VV2_0870	COG3284	Transcriptional regulator
VV2_0872	COG1879	ABC-type sugar transport system periplasmic component
VV2_0873	COG0625	glutathione transferase activity
VV2_0875	COG0384	phenazine biosynthesis protein PhzF
VV2_0877	COG2197	response regulator
VV2_0879	COG0673	inositol 2-dehydrogenase activity
VV2_0885	COG2015	COG2015, Alkyl sulfatase and related hydrolases
VV2_0888	COG0583	DNA-binding transcription factor activity
VV2_0889	COG2194	sulfuric ester hydrolase activity
VV2_0893	COG0798	PFAM Bile acid sodium symporter
VV2_0894	COG0640	Transcriptional regulator
VV2_0898	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VV2_0899	COG0700	Nucleoside recognition
VV2_0900	COG3366	ferrous iron transmembrane transporter activity
VV2_0903	COG0366	Alpha amylase catalytic
VV2_0904	COG0800	Aldolase
VV2_0905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VV2_0906	COG0697	spore germination
VV2_0912	COG1917	Cupin 2, conserved barrel domain protein
VV2_0914	COG1028	Short-chain dehydrogenase reductase Sdr
VV2_0920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VV2_0920	COG3153	acetyltransferase
VV2_0925	COG0668	transmembrane transport
VV2_0932	COG0494	nUDIX hydrolase
VV2_0933	COG1881	PFAM PEBP family protein
VV2_0934	COG2207	Transcriptional regulator
VV2_0935	COG3046	protein related to deoxyribodipyrimidine photolyase
VV2_0941	COG0454	-acetyltransferase
VV2_0942	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VV2_0949	COG1858	cytochrome C peroxidase
VV2_0953	COG0583	DNA-binding transcription factor activity
VV2_0957	COG2814	Major facilitator Superfamily
VV2_0962	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VV2_0964	COG0583	DNA-binding transcription factor activity
VV2_0968	COG0513	Belongs to the DEAD box helicase family
VV2_0975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VV2_0977	COG1357	PFAM Pentapeptide repeats (8 copies)
VV2_0981	COG3437	response regulator, receiver
VV2_0983	COG0579	oxidoreductase
VV2_0989	COG2015	COG2015, Alkyl sulfatase and related hydrolases
VV2_0992	COG2205	protein histidine kinase activity
VV2_0996	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
VV2_1000	COG3706	GGDEF domain
VV2_1003	COG2176	DNA-directed DNA polymerase activity
VV2_1004	COG1136	(ABC) transporter
VV2_1004	COG0577	efflux transmembrane transporter activity
VV2_1005	COG1136	(ABC) transporter
VV2_1005	COG0577	efflux transmembrane transporter activity
VV2_1011	COG1120	ATPase activity
VV2_1012	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VV2_1019	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
VV2_1020	COG3716	PTS system mannose fructose sorbose family IID component
VV2_1022	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VV2_1023	COG2222	sugar isomerase
VV2_1025	COG1349	DNA-binding transcription factor activity
VV2_1026	COG1349	DNA-binding transcription factor activity
VV2_1027	COG0697	spore germination
VV2_1032	COG2015	COG2015, Alkyl sulfatase and related hydrolases
VV2_1037	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VV2_1038	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VV2_1042	COG0840	transmembrane signaling receptor activity
VV2_1045	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VV2_1047	COG3385	transposase activity
VV2_1049	COG0583	DNA-binding transcription factor activity
VV2_1050	COG1486	melibiose metabolic process
VV2_1052	COG1522	sequence-specific DNA binding
VV2_1055	COG2258	MOSC domain
VV2_1061	COG1757	Na H antiporter
VV2_1062	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
VV2_1063	COG0513	Belongs to the DEAD box helicase family
VV2_1065	COG2186	Transcriptional regulator
VV2_1067	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VV2_1069	COG0246	Mannitol dehydrogenase
VV2_1071	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VV2_1072	COG0800	Aldolase
VV2_1075	COG1028	Short-chain dehydrogenase reductase Sdr
VV2_1076	COG2999	glutathione oxidoreductase activity
VV2_1077	COG1902	pentaerythritol trinitrate reductase activity
VV2_1083	COG0561	phosphatase activity
VV2_1084	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
VV2_1085	COG3623	hexulose-6-phosphate isomerase
VV2_1089	COG1132	(ABC) transporter
VV2_1090	COG5492	domain, Protein
VV2_1091	COG5426	von Willebrand factor, type A
VV2_1093	COG1028	Short-chain dehydrogenase reductase Sdr
VV2_1095	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VV2_1096	COG0659	secondary active sulfate transmembrane transporter activity
VV2_1101	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VV2_1102	COG0601	transmembrane transport
VV2_1104	COG0747	negative chemotaxis
VV2_1106	COG3119	arylsulfatase activity
VV2_1107	COG0641	radical SAM
VV2_1108	COG3119	arylsulfatase activity
VV2_1109	COG3119	arylsulfatase activity
VV2_1110	COG5492	domain, Protein
VV2_1116	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VV2_1124	COG2204	response regulator
VV2_1130	COG3069	C4-dicarboxylate transmembrane transporter activity
VV2_1131	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VV2_1136	COG0110	maltose O-acetyltransferase activity
VV2_1139	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VV2_1139	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VV2_1140	COG1737	Transcriptional regulator
VV2_1144	COG2199	diguanylate cyclase activity
VV2_1144	COG2203	Gaf domain
VV2_1144	COG2200	EAL domain
VV2_1145	COG0406	alpha-ribazole phosphatase activity
VV2_1148	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VV2_1154	COG0515	serine threonine protein kinase
VV2_1154	COG2815	serine threonine protein kinase
VV2_1158	COG0745	RESPONSE REGULATOR receiver
VV2_1158	COG3706	GGDEF domain
VV2_1160	COG0840	transmembrane signaling receptor activity
VV2_1163	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VV2_1165	COG0840	transmembrane signaling receptor activity
VV2_1166	COG0835	chemotaxis
VV2_1169	COG0745	RESPONSE REGULATOR receiver
VV2_1171	COG1444	tRNA N-acetyltransferase activity
VV2_1177	COG4608	Belongs to the ABC transporter superfamily
VV2_1178	COG0444	Belongs to the ABC transporter superfamily
VV2_1180	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VV2_1180	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
VV2_1184	COG0217	transcriptional regulatory protein
VV2_1186	COG0583	DNA-binding transcription factor activity
VV2_1188	COG1136	(ABC) transporter
VV2_1189	COG4591	ABC-type transport system involved in lipoprotein release permease component
VV2_1192	COG3275	phosphorelay sensor kinase activity
VV2_1197	COG0786	glutamate:sodium symporter activity
VV2_1198	COG0786	glutamate:sodium symporter activity
VV2_1204	COG0189	ligase activity
VV2_1208	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
VV2_1209	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
VV2_1211	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
VV2_1215	COG1309	transcriptional regulator
VV2_1220	COG1741	Belongs to the pirin family
VV2_1222	COG5001	Diguanylate cyclase
VV2_1225	COG3706	GGDEF domain
VV2_1235	COG1982	Orn Lys Arg decarboxylase major
VV2_1236	COG0531	amino acid
VV2_1240	COG2847	Copper chaperone PCu(A)C
VV2_1241	COG1999	signal sequence binding
VV2_1250	COG0058	SHG alpha-glucan phosphorylase activity
VV2_1251	COG1640	4-alpha-glucanotransferase
VV2_1261	COG0560	Phosphoserine phosphatase
VV2_1266	COG1012	belongs to the aldehyde dehydrogenase family
VV2_1267	COG0625	glutathione transferase activity
VV2_1268	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VV2_1269	COG1283	sodium-dependent phosphate transmembrane transporter activity
VV2_1270	COG0612	Peptidase, M16
VV2_1272	COG0583	DNA-binding transcription factor activity
VV2_1273	COG0583	DNA-binding transcription factor activity
VV2_1274	COG0387	Pfam Sodium calcium exchanger
VV2_1275	COG0586	Pfam SNARE associated Golgi protein
VV2_1277	COG0642	Histidine kinase
VV2_1278	COG0745	RESPONSE REGULATOR receiver
VV2_1279	COG2199	diguanylate cyclase activity
VV2_1282	COG1609	Transcriptional regulator
VV2_1286	COG0395	ABC-type sugar transport system, permease component
VV2_1289	COG1609	Transcriptional regulator
VV2_1291	COG0747	negative chemotaxis
VV2_1293	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VV2_1294	COG0444	Belongs to the ABC transporter superfamily
VV2_1295	COG4608	Belongs to the ABC transporter superfamily
VV2_1297	COG1609	Transcriptional regulator
VV2_1301	COG4580	involved in the transport of maltose and maltodextrins
VV2_1304	COG1472	Belongs to the glycosyl hydrolase 3 family
VV2_1306	COG0534	Mate efflux family protein
VV2_1308	COG1566	PFAM secretion protein HlyD family protein
VV2_1318	COG0564	pseudouridine synthase activity
VV2_1323	COG1609	Transcriptional regulator
VV2_1329	COG4580	involved in the transport of maltose and maltodextrins
VV2_1332	COG2211	Major facilitator Superfamily
VV2_1334	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VV2_1335	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
VV2_1336	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
VV2_1338	COG2207	Transcriptional regulator
VV2_1338	COG3708	Transcriptional regulator
VV2_1348	COG1482	cell wall glycoprotein biosynthetic process
VV2_1349	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VV2_1349	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VV2_1349	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VV2_1350	COG2207	Transcriptional regulator
VV2_1352	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VV2_1353	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VV2_1354	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VV2_1356	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VV2_1360	COG3383	formate dehydrogenase (NAD+) activity
VV2_1363	COG0583	DNA-binding transcription factor activity
VV2_1364	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
VV2_1365	COG0583	DNA-binding transcription factor activity
VV2_1370	COG0768	penicillin binding
VV2_1373	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VV2_1377	COG0583	DNA-binding transcription factor activity
VV2_1381	COG0137	argininosuccinate synthase activity
VV2_1383	COG1301	dicarboxylic acid transport
VV2_1395	COG2175	clavaminate synthase activity
VV2_1401	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VV2_1403	COG3706	GGDEF domain
VV2_1406	COG2356	endonuclease I
VV2_1410	COG1368	sulfuric ester hydrolase activity
VV2_1411	COG2194	sulfuric ester hydrolase activity
VV2_1412	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VV2_1413	COG2205	protein histidine kinase activity
VV2_1414	COG0745	RESPONSE REGULATOR receiver
VV2_1418	COG4221	oxidoreductase activity
VV2_1424	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VV2_1425	COG0076	glutamate decarboxylase activity
VV2_1429	COG0561	phosphatase activity
VV2_1432	COG0671	phosphoesterase, PA-phosphatase related
VV2_1433	COG0351	phosphomethylpyrimidine kinase
VV2_1458	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VV2_1460	COG4771	TonB-dependent receptor
VV2_1464	COG0393	Putative heavy-metal-binding
VV2_1467	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VV2_1477	COG0346	lactoylglutathione lyase activity
VV2_1479	COG2211	Major facilitator Superfamily
VV2_1483	COG3240	lipase activity
VV2_1500	COG3040	lipid binding
VV2_1505	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
VV2_1508	COG2197	response regulator
VV2_1510	COG2197	response regulator
VV2_1512	COG0784	Response regulator, receiver
VV2_1512	COG2205	protein histidine kinase activity
VV2_1513	COG3111	PFAM Bacterial OB fold (BOF) protein
VV2_1515	COG2274	protein secretion by the type I secretion system
VV2_1517	COG1538	Outer membrane efflux protein
VV2_1521	COG0668	transmembrane transport
VV2_1528	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VV2_1529	COG4946	Tricorn protease homolog
VV2_1529	COG0793	Belongs to the peptidase S41A family
VV2_1534	COG4720	Psort location CytoplasmicMembrane, score
VV2_1535	COG1566	PFAM secretion protein HlyD family protein
VV2_1537	COG3706	GGDEF domain
VV2_1541	COG3272	Protein of unknown function (DUF1722)
VV2_1542	COG0789	Transcriptional regulator
VV2_1543	COG0415	Belongs to the DNA photolyase family
VV2_1544	COG1388	LysM domain
VV2_1544	COG1376	ErfK ybiS ycfS ynhG family protein
VV2_1546	COG0513	Belongs to the DEAD box helicase family
VV2_1556	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VV2_1557	COG0573	inorganic phosphate transmembrane transporter activity
VV2_1558	COG0581	inorganic phosphate transmembrane transporter activity
VV2_1560	COG2203	Gaf domain
VV2_1560	COG5001	Diguanylate cyclase
VV2_1560	COG4251	negative regulation of phosphorylation
VV2_1560	COG3706	GGDEF domain
VV2_1562	COG2304	oxidoreductase activity
VV2_1566	COG0714	Associated with various cellular activities
VV2_1580	COG1596	polysaccharide export
VV2_1582	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VV2_1594	COG2354	Protein conserved in bacteria
VV2_1598	COG3217	Mosc domain protein beta barrel domain protein
VV2_1598	COG3217	Mosc domain protein beta barrel domain protein
VV2_1598	COG0633	Ferredoxin
VV2_1598	COG0633	Ferredoxin
VV2_1610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VV2_1612	COG0848	biopolymer transport protein
VV2_1613	COG0811	peptide transport
VV2_1614	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VV2_1616	COG3721	Heme iron utilization protein
VV2_1617	COG0748	coenzyme F420 binding
VV2_1619	COG0835	chemotaxis
VV2_1619	COG0784	Response regulator, receiver
VV2_1620	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VV2_1621	COG0589	response to stress
VV2_1622	COG0366	Alpha amylase catalytic
VV2_1624	COG0840	transmembrane signaling receptor activity
VV2_1633	COG0739	heme binding
VV2_1634	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VV2_1637	COG2084	Dehydrogenase
VV2_1641	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VV2_1645	COG0840	transmembrane signaling receptor activity
VV2_1648	COG3706	GGDEF domain
VV2_1649	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VV2_1649	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VV2_1650	COG1765	OsmC-like protein
VV2_1651	COG2171	N-acyltransferase activity
VV2_1655	COG1011	Hydrolase
VV2_1658	COG0840	transmembrane signaling receptor activity
VV2_1660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VV2_1661	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VV2_1661	COG2207	Transcriptional regulator
VV2_1665	COG1840	ABC-type Fe3 transport system, periplasmic component
VV2_1669	COG3842	ATPase activity
VV2_1673	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VV2_1674	COG0583	DNA-binding transcription factor activity
VV2_1677	COG1760	l-serine dehydratase
VV2_1681	COG1686	Belongs to the peptidase S11 family
VV2_1693	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein