locus-tag	class	description
AL549_00035	COG0633	Ferredoxin
AL549_00035	COG3217	Mosc domain protein beta barrel domain protein
AL549_00035	COG0633	Ferredoxin
AL549_00035	COG3217	Mosc domain protein beta barrel domain protein
AL549_00040	COG0418	dihydroorotase activity
AL549_00050	COG2354	Protein conserved in bacteria
AL549_00100	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL549_00110	COG1596	polysaccharide export
AL549_00115	COG0489	protein tyrosine kinase activity
AL549_00115	COG3206	protein involved in exopolysaccharide biosynthesis
AL549_00180	COG0714	Associated with various cellular activities
AL549_00200	COG2304	oxidoreductase activity
AL549_00210	COG4251	negative regulation of phosphorylation
AL549_00210	COG5001	Diguanylate cyclase
AL549_00210	COG3706	GGDEF domain
AL549_00210	COG2203	Gaf domain
AL549_00215	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL549_00220	COG0581	inorganic phosphate transmembrane transporter activity
AL549_00225	COG0573	inorganic phosphate transmembrane transporter activity
AL549_00230	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL549_00265	COG0513	Belongs to the DEAD box helicase family
AL549_00275	COG1376	ErfK ybiS ycfS ynhG family protein
AL549_00275	COG1388	LysM domain
AL549_00280	COG0415	Belongs to the DNA photolyase family
AL549_00285	COG0789	Transcriptional regulator
AL549_00290	COG3272	Protein of unknown function (DUF1722)
AL549_00310	COG3706	GGDEF domain
AL549_00320	COG1566	PFAM secretion protein HlyD family protein
AL549_00325	COG4720	Psort location CytoplasmicMembrane, score
AL549_00345	COG0793	Belongs to the peptidase S41A family
AL549_00345	COG4946	Tricorn protease homolog
AL549_00350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL549_00375	COG0668	transmembrane transport
AL549_00405	COG2274	protein secretion by the type I secretion system
AL549_00415	COG3111	PFAM Bacterial OB fold (BOF) protein
AL549_00420	COG0784	Response regulator, receiver
AL549_00420	COG2205	protein histidine kinase activity
AL549_00440	COG2197	response regulator
AL549_00450	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AL549_00480	COG3040	lipid binding
AL549_00540	COG3240	lipase activity
AL549_00555	COG2211	Major facilitator Superfamily
AL549_00565	COG0346	lactoylglutathione lyase activity
AL549_00580	COG0753	catalase activity
AL549_00600	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AL549_00610	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL549_00625	COG0393	Putative heavy-metal-binding
AL549_00645	COG4771	TonB-dependent receptor
AL549_00650	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL549_00675	COG2814	Major facilitator Superfamily
AL549_00740	COG0351	phosphomethylpyrimidine kinase
AL549_00745	COG0671	phosphoesterase, PA-phosphatase related
AL549_00760	COG0561	phosphatase activity
AL549_00775	COG0076	glutamate decarboxylase activity
AL549_00780	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL549_00805	COG4221	oxidoreductase activity
AL549_00820	COG0745	RESPONSE REGULATOR receiver
AL549_00825	COG2205	protein histidine kinase activity
AL549_00830	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL549_00835	COG2194	sulfuric ester hydrolase activity
AL549_00840	COG1368	sulfuric ester hydrolase activity
AL549_00855	COG2356	endonuclease I
AL549_00870	COG3706	GGDEF domain
AL549_00880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL549_00915	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL549_00960	COG1301	dicarboxylic acid transport
AL549_00970	COG0137	argininosuccinate synthase activity
AL549_00990	COG1733	regulation of RNA biosynthetic process
AL549_00995	COG0583	DNA-binding transcription factor activity
AL549_01015	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AL549_01055	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AL549_01060	COG0583	DNA-binding transcription factor activity
AL549_01070	COG3383	formate dehydrogenase (NAD+) activity
AL549_01090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL549_01100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL549_01110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL549_01115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL549_01125	COG2207	Transcriptional regulator
AL549_01130	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL549_01130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL549_01130	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL549_01135	COG1482	cell wall glycoprotein biosynthetic process
AL549_01195	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AL549_01200	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AL549_01205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL549_01215	COG2211	Major facilitator Superfamily
AL549_01235	COG1129	ABC transporter
AL549_01245	COG1609	Transcriptional regulator
AL549_01270	COG0564	pseudouridine synthase activity
AL549_01305	COG1566	PFAM secretion protein HlyD family protein
AL549_01315	COG0534	Mate efflux family protein
AL549_01320	COG1472	Belongs to the glycosyl hydrolase 3 family
AL549_01330	COG4580	involved in the transport of maltose and maltodextrins
AL549_01345	COG1609	Transcriptional regulator
AL549_01355	COG4608	Belongs to the ABC transporter superfamily
AL549_01360	COG0444	Belongs to the ABC transporter superfamily
AL549_01365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL549_01375	COG0747	negative chemotaxis
AL549_01385	COG1609	Transcriptional regulator
AL549_01400	COG0395	ABC-type sugar transport system, permease component
AL549_01415	COG1609	Transcriptional regulator
AL549_01435	COG2199	diguanylate cyclase activity
AL549_01440	COG0745	RESPONSE REGULATOR receiver
AL549_01445	COG0642	Histidine kinase
AL549_01455	COG0583	DNA-binding transcription factor activity
AL549_01465	COG0612	Peptidase, M16
AL549_01470	COG1283	sodium-dependent phosphate transmembrane transporter activity
AL549_01475	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL549_01480	COG0625	glutathione transferase activity
AL549_01485	COG1012	belongs to the aldehyde dehydrogenase family
AL549_01505	COG0560	Phosphoserine phosphatase
AL549_01540	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL549_01545	COG0840	transmembrane signaling receptor activity
AL549_01555	COG1640	4-alpha-glucanotransferase
AL549_01560	COG0058	SHG alpha-glucan phosphorylase activity
AL549_01580	COG1999	signal sequence binding
AL549_01585	COG2847	Copper chaperone PCu(A)C
AL549_01590	COG1162	GTPase activity
AL549_01595	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AL549_01605	COG0531	amino acid
AL549_01610	COG1982	Orn Lys Arg decarboxylase major
AL549_01665	COG3706	GGDEF domain
AL549_01670	COG5001	Diguanylate cyclase
AL549_01680	COG1741	Belongs to the pirin family
AL549_01705	COG1309	transcriptional regulator
AL549_01730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AL549_01735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL549_01740	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AL549_01760	COG0189	ligase activity
AL549_01785	COG0786	glutamate:sodium symporter activity
AL549_01790	COG0786	glutamate:sodium symporter activity
AL549_01810	COG3275	phosphorelay sensor kinase activity
AL549_01825	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL549_01830	COG1136	(ABC) transporter
AL549_01840	COG0583	DNA-binding transcription factor activity
AL549_01850	COG0217	transcriptional regulatory protein
AL549_01870	COG3385	transposase activity
AL549_01885	COG0444	Belongs to the ABC transporter superfamily
AL549_01890	COG4608	Belongs to the ABC transporter superfamily
AL549_01915	COG1444	tRNA N-acetyltransferase activity
AL549_01925	COG0745	RESPONSE REGULATOR receiver
AL549_01940	COG0835	chemotaxis
AL549_01945	COG0840	transmembrane signaling receptor activity
AL549_01950	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL549_01955	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AL549_01960	COG2201	protein-glutamate methylesterase activity
AL549_01965	COG0840	transmembrane signaling receptor activity
AL549_01975	COG0745	RESPONSE REGULATOR receiver
AL549_01975	COG3706	GGDEF domain
AL549_02010	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AL549_02015	COG0583	DNA-binding transcription factor activity
AL549_02025	COG0406	alpha-ribazole phosphatase activity
AL549_02030	COG2203	Gaf domain
AL549_02030	COG2200	EAL domain
AL549_02030	COG2199	diguanylate cyclase activity
AL549_02040	COG1263	PTS System
AL549_02040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL549_02050	COG1737	Transcriptional regulator
AL549_02055	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL549_02055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL549_02065	COG0110	maltose O-acetyltransferase activity
AL549_02110	COG2204	response regulator
AL549_02145	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL549_02160	COG5492	domain, Protein
AL549_02165	COG3119	arylsulfatase activity
AL549_02170	COG3119	arylsulfatase activity
AL549_02175	COG0641	radical SAM
AL549_02180	COG3119	arylsulfatase activity
AL549_02190	COG0747	negative chemotaxis
AL549_02195	COG0601	transmembrane transport
AL549_02200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL549_02225	COG0659	secondary active sulfate transmembrane transporter activity
AL549_02230	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL549_02240	COG1028	Short-chain dehydrogenase reductase Sdr
AL549_02250	COG5426	von Willebrand factor, type A
AL549_02255	COG5492	domain, Protein
AL549_02260	COG1132	(ABC) transporter
AL549_02275	COG3623	hexulose-6-phosphate isomerase
AL549_02280	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AL549_02285	COG0561	phosphatase activity
AL549_02315	COG1902	pentaerythritol trinitrate reductase activity
AL549_02320	COG2999	glutathione oxidoreductase activity
AL549_02325	COG1028	Short-chain dehydrogenase reductase Sdr
AL549_02340	COG0800	Aldolase
AL549_02345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL549_02350	COG1904	glucuronate isomerase
AL549_02355	COG0246	Mannitol dehydrogenase
AL549_02365	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL549_02375	COG2186	Transcriptional regulator
AL549_02385	COG0513	Belongs to the DEAD box helicase family
AL549_02390	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AL549_02395	COG1757	Na H antiporter
AL549_02405	COG1335	isochorismatase
AL549_02415	COG0697	spore germination
AL549_02425	COG2258	MOSC domain
AL549_02445	COG1486	melibiose metabolic process
AL549_02450	COG0583	DNA-binding transcription factor activity
AL549_02470	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL549_02485	COG0840	transmembrane signaling receptor activity
AL549_02505	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL549_02510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL549_02535	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AL549_02555	COG0697	spore germination
AL549_02560	COG1349	DNA-binding transcription factor activity
AL549_02565	COG1349	DNA-binding transcription factor activity
AL549_02575	COG2222	sugar isomerase
AL549_02580	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL549_02590	COG3716	PTS system mannose fructose sorbose family IID component
AL549_02595	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL549_02610	COG0488	(ABC) transporter
AL549_02630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL549_02635	COG1120	ATPase activity
AL549_02665	COG1136	(ABC) transporter
AL549_02665	COG0577	efflux transmembrane transporter activity
AL549_02670	COG0577	efflux transmembrane transporter activity
AL549_02670	COG1136	(ABC) transporter
AL549_02675	COG2176	DNA-directed DNA polymerase activity
AL549_02695	COG3706	GGDEF domain
AL549_02710	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL549_02730	COG2205	protein histidine kinase activity
AL549_02745	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AL549_02775	COG0579	oxidoreductase
AL549_02785	COG3437	response regulator, receiver
AL549_02805	COG1357	PFAM Pentapeptide repeats (8 copies)
AL549_02815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL549_02850	COG0513	Belongs to the DEAD box helicase family
AL549_02870	COG0583	DNA-binding transcription factor activity
AL549_02880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL549_02910	COG2814	Major facilitator Superfamily
AL549_02930	COG0583	DNA-binding transcription factor activity
AL549_02950	COG1858	cytochrome C peroxidase
AL549_02975	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL549_02980	COG0454	-acetyltransferase
AL549_03000	COG2205	protein histidine kinase activity
AL549_03005	COG0745	RESPONSE REGULATOR receiver
AL549_03025	COG3046	protein related to deoxyribodipyrimidine photolyase
AL549_03030	COG2207	Transcriptional regulator
AL549_03035	COG1881	PFAM PEBP family protein
AL549_03040	COG0494	nUDIX hydrolase
AL549_03070	COG0668	transmembrane transport
AL549_03090	COG3153	acetyltransferase
AL549_03090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL549_03120	COG1028	Short-chain dehydrogenase reductase Sdr
AL549_03130	COG1917	Cupin 2, conserved barrel domain protein
AL549_03150	COG0697	spore germination
AL549_03155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL549_03160	COG0800	Aldolase
AL549_03190	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL549_03195	COG0823	Involved in the tonB-independent uptake of proteins
AL549_03200	COG0366	Alpha amylase catalytic
AL549_03210	COG3366	ferrous iron transmembrane transporter activity
AL549_03215	COG0700	Nucleoside recognition
AL549_03220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL549_03255	COG0640	Transcriptional regulator
AL549_03260	COG0798	PFAM Bile acid sodium symporter
AL549_03280	COG2194	sulfuric ester hydrolase activity
AL549_03285	COG0583	DNA-binding transcription factor activity
AL549_03295	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AL549_03320	COG0673	inositol 2-dehydrogenase activity
AL549_03325	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL549_03330	COG2197	response regulator
AL549_03335	COG0384	phenazine biosynthesis protein PhzF
AL549_03350	COG1879	ABC-type sugar transport system periplasmic component
AL549_03360	COG3284	Transcriptional regulator
AL549_03365	COG1012	belongs to the aldehyde dehydrogenase family
AL549_03375	COG1253	flavin adenine dinucleotide binding
AL549_03400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL549_03405	COG1609	Transcriptional regulator
AL549_03425	COG0488	(ABC) transporter
AL549_03430	COG0814	amino acid
AL549_03445	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL549_03470	COG4067	protein conserved in archaea
AL549_03470	COG0189	ligase activity
AL549_03490	COG4774	siderophore transport
AL549_03490	COG1629	transport
AL549_03495	COG4607	ABC-type enterochelin transport system periplasmic component
AL549_03505	COG1021	2,3-dihydroxybenzoate-AMP ligase
AL549_03525	COG1021	2,3-dihydroxybenzoate-AMP ligase
AL549_03530	COG1169	isochorismate synthase
AL549_03535	COG1028	Short-chain dehydrogenase reductase Sdr
AL549_03540	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL549_03555	COG2977	Belongs to the P-Pant transferase superfamily
AL549_03570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL549_03575	COG0840	transmembrane signaling receptor activity
AL549_03585	COG2755	lipolytic protein G-D-S-L family
AL549_03590	COG5001	Diguanylate cyclase
AL549_03590	COG5002	protein histidine kinase activity
AL549_03605	COG4160	amino acid transport
AL549_03610	COG4215	(ABC) transporter
AL549_03615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL549_03620	COG1126	abc transporter atp-binding protein
AL549_03625	COG3015	lipoprotein NlpE involved in copper resistance
AL549_03640	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL549_03680	COG2814	Major facilitator Superfamily
AL549_03705	COG1139	Iron-sulfur cluster binding protein
AL549_03715	COG1620	l-lactate permease
AL549_03720	COG0583	DNA-binding transcription factor activity
AL549_03725	COG1505	serine-type exopeptidase activity
AL549_03730	COG4172	Belongs to the ABC transporter superfamily
AL549_03740	COG1067	ATP-dependent peptidase activity
AL549_03745	COG0402	S-adenosylhomocysteine deaminase activity
AL549_03750	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AL549_03760	COG2239	Acts as a magnesium transporter
AL549_03785	COG0745	RESPONSE REGULATOR receiver
AL549_03790	COG2205	protein histidine kinase activity
AL549_03805	COG0121	glutamine amidotransferase
AL549_03810	COG0531	amino acid
AL549_03820	COG1522	sequence-specific DNA binding
AL549_03845	COG0583	DNA-binding transcription factor activity
AL549_03870	COG5002	protein histidine kinase activity
AL549_03870	COG2205	protein histidine kinase activity
AL549_03870	COG0784	Response regulator, receiver
AL549_03895	COG2827	Endonuclease containing a URI domain
AL549_03905	COG1879	ABC-type sugar transport system periplasmic component
AL549_03950	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL549_03955	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL549_03965	COG0183	Belongs to the thiolase family
AL549_03985	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AL549_03990	COG1940	carbohydrate kinase activity
AL549_04000	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL549_04005	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL549_04010	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL549_04015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL549_04020	COG1737	Transcriptional regulator
AL549_04025	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
AL549_04030	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
AL549_04035	COG3005	denitrification pathway
AL549_04045	COG0243	molybdopterin cofactor binding
AL549_04055	COG3850	Histidine kinase
AL549_04060	COG2197	response regulator
AL549_04080	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL549_04080	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL549_04140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL549_04155	COG3568	Endonuclease Exonuclease Phosphatase
AL549_04180	COG0513	Belongs to the DEAD box helicase family
AL549_04190	COG2514	catechol 2,3-dioxygenase activity
AL549_04195	COG1846	Transcriptional regulator
AL549_04225	COG0842	Transport permease protein
AL549_04230	COG1131	(ABC) transporter
AL549_04240	COG1737	Transcriptional regulator
AL549_04240	COG0837	glucose binding
AL549_04250	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL549_04260	COG4145	pantothenate transmembrane transporter activity
AL549_04275	COG0251	oxidation-reduction process
AL549_04280	COG5001	Diguanylate cyclase
AL549_04280	COG4251	negative regulation of phosphorylation
AL549_04280	COG3706	GGDEF domain
AL549_04280	COG2203	Gaf domain
AL549_04285	COG0583	DNA-binding transcription factor activity
AL549_04290	COG2814	Major facilitator Superfamily
AL549_04305	COG0697	spore germination
AL549_04320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL549_04330	COG1764	response to oxidative stress
AL549_04335	COG1846	Transcriptional regulator
AL549_04360	COG1280	lysine exporter protein (LysE YggA)
AL549_04370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL549_04375	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL549_04380	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL549_04385	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AL549_04410	COG1612	heme a metabolic process
AL549_04415	COG0109	protoheme IX farnesyltransferase activity
AL549_04420	COG2885	chlorophyll binding
AL549_04425	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL549_04430	COG0840	transmembrane signaling receptor activity
AL549_04470	COG2897	thiosulfate sulfurtransferase activity
AL549_04475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL549_04480	COG0303	'Molybdopterin
AL549_04490	COG1914	H( )-stimulated, divalent metal cation uptake system
AL549_04520	COG4989	oxidoreductase activity
AL549_04530	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL549_04550	COG0840	transmembrane signaling receptor activity
AL549_04555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL549_04560	COG0545	Peptidyl-prolyl cis-trans isomerase
AL549_04590	COG1278	Cold shock
AL549_04595	COG3036	rescue of stalled ribosome
AL549_04605	COG2203	Gaf domain
AL549_04605	COG2199	diguanylate cyclase activity
AL549_04615	COG1482	cell wall glycoprotein biosynthetic process
AL549_04620	COG2271	Major facilitator Superfamily
AL549_04625	COG3851	Histidine kinase
AL549_04630	COG2197	response regulator
AL549_04650	COG2130	NADP-dependent
AL549_04655	COG1309	transcriptional regulator
AL549_04670	COG1278	Cold shock
AL549_04675	COG3634	alkyl hydroperoxide reductase activity
AL549_04680	COG0450	alkyl hydroperoxide reductase
AL549_04695	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL549_04700	COG1960	acyl-CoA dehydrogenase activity
AL549_04710	COG0183	Belongs to the thiolase family
AL549_04720	COG1960	acyl-CoA dehydrogenase activity
AL549_04725	COG1024	Enoyl-CoA hydratase
AL549_04730	COG1024	Enoyl-CoA hydratase
AL549_04740	COG1028	Short-chain dehydrogenase reductase Sdr
AL549_04780	COG2994	toxin metabolic process
AL549_04785	COG3064	Membrane
AL549_04785	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AL549_04785	COG1073	alpha beta
AL549_04840	COG0784	Response regulator, receiver
AL549_04840	COG3437	response regulator, receiver
AL549_04845	COG4191	Histidine kinase
AL549_04845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL549_04855	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AL549_04880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL549_04885	COG3186	Phenylalanine-4-hydroxylase
AL549_04910	COG3530	Putative quorum-sensing-regulated virulence factor
AL549_04930	COG0515	serine threonine protein kinase
AL549_04930	COG2815	serine threonine protein kinase
AL549_04965	COG0631	protein serine/threonine phosphatase activity
AL549_05020	COG3501	Rhs element vgr protein
AL549_05035	COG3209	COG3209 Rhs family protein
AL549_05095	COG0501	Belongs to the peptidase M48B family
AL549_05100	COG1704	LemA family
AL549_05105	COG3069	C4-dicarboxylate transmembrane transporter activity
AL549_05115	COG0312	modulator of DNA gyrase
AL549_05120	COG0312	modulator of DNA gyrase
AL549_05125	COG0584	glycerophosphoryl diester phosphodiesterase
AL549_05130	COG2271	Major facilitator Superfamily
AL549_05145	COG0840	transmembrane signaling receptor activity
AL549_05150	COG0840	transmembrane signaling receptor activity
AL549_05155	COG0366	Alpha amylase catalytic
AL549_05160	COG0456	acetyltransferase
AL549_05165	COG0243	molybdopterin cofactor binding
AL549_05170	COG1648	precorrin-2 dehydrogenase activity
AL549_05170	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL549_05185	COG3707	response regulator
AL549_05190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL549_05190	COG1116	anion transmembrane transporter activity
AL549_05195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL549_05200	COG1116	anion transmembrane transporter activity
AL549_05205	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL549_05205	COG2146	nitrite reductase [NAD(P)H] activity
AL549_05220	COG2199	diguanylate cyclase activity
AL549_05230	COG0523	cobalamin synthesis protein
AL549_05240	COG0513	Belongs to the DEAD box helicase family
AL549_05245	COG0010	Belongs to the arginase family
AL549_05255	COG5001	Diguanylate cyclase
AL549_05255	COG3706	GGDEF domain
AL549_05255	COG4251	negative regulation of phosphorylation
AL549_05255	COG2203	Gaf domain
AL549_05265	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL549_05295	COG0840	transmembrane signaling receptor activity
AL549_05300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL549_05305	COG2146	nitrite reductase [NAD(P)H] activity
AL549_05335	COG0811	peptide transport
AL549_05340	COG0811	peptide transport
AL549_05345	COG0848	biopolymer transport protein
AL549_05360	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL549_05380	COG0534	Mate efflux family protein
AL549_05390	COG0477	Major facilitator Superfamily
AL549_05395	COG3118	belongs to the thioredoxin family
AL549_05400	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL549_05455	COG1328	CTP reductase activity
AL549_05460	COG0602	queuosine metabolic process
AL549_05465	COG0840	transmembrane signaling receptor activity
AL549_05475	COG4067	protein conserved in archaea
AL549_05475	COG0189	ligase activity
AL549_05480	COG3385	transposase activity
AL549_05500	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL549_05505	COG4149	molybdate abc transporter
AL549_05515	COG0697	spore germination
AL549_05520	COG1846	Transcriptional regulator
AL549_05530	COG0745	RESPONSE REGULATOR receiver
AL549_05540	COG3706	GGDEF domain
AL549_05555	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AL549_05560	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AL549_05570	COG0745	RESPONSE REGULATOR receiver
AL549_05590	COG0023	Translation Initiation Factor
AL549_05600	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL549_05610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL549_05610	COG1042	CoA-binding domain protein
AL549_05610	COG0045	succinate-CoA ligase (ADP-forming) activity
AL549_05615	COG0583	DNA-binding transcription factor activity
AL549_05625	COG5001	Diguanylate cyclase
AL549_05625	COG5002	protein histidine kinase activity
AL549_05625	COG3447	MASE1 domain protein
AL549_05635	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AL549_05640	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AL549_05645	COG1984	allophanate hydrolase subunit 2
AL549_05650	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AL549_05650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL549_05655	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL549_05660	COG4181	ATPase activity
AL549_05670	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL549_05675	COG5001	Diguanylate cyclase
AL549_05675	COG1716	ATPase activity
AL549_05690	COG0484	heat shock protein binding
AL549_05710	COG0583	DNA-binding transcription factor activity
AL549_05715	COG0366	Alpha amylase catalytic
AL549_05725	COG4533	DNA binding
AL549_05735	COG2050	protein possibly involved in aromatic compounds catabolism
AL549_05750	COG2067	long-chain fatty acid transport protein
AL549_05755	COG2267	carboxylic ester hydrolase activity
AL549_05785	COG0861	Integral membrane protein TerC family
AL549_05790	COG0737	Belongs to the 5'-nucleotidase family
AL549_05795	COG3593	DNA synthesis involved in DNA repair
AL549_05805	COG0583	DNA-binding transcription factor activity
AL549_05810	COG2116	formate transmembrane transporter activity
AL549_05820	COG3038	cytochrome b561
AL549_05835	COG0513	Belongs to the DEAD box helicase family
AL549_05850	COG0546	phosphoglycolate phosphatase activity
AL549_05855	COG3437	response regulator, receiver
AL549_05855	COG0784	Response regulator, receiver
AL549_05870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL549_05890	COG2207	Transcriptional regulator
AL549_05895	COG1979	alcohol dehydrogenase
AL549_05905	COG4191	Histidine kinase
AL549_05910	COG1840	ABC-type Fe3 transport system, periplasmic component
AL549_05915	COG2271	Major facilitator Superfamily
AL549_05920	COG0469	pyruvate kinase activity
AL549_05945	COG1609	Transcriptional regulator
AL549_05950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL549_05950	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL549_05955	COG1105	Belongs to the carbohydrate kinase PfkB family
AL549_05960	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL549_05960	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL549_05960	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AL549_06005	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL549_06015	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL549_06015	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL549_06035	COG1132	(ABC) transporter
AL549_06045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL549_06075	COG2814	Major facilitator Superfamily
AL549_06105	COG0641	radical SAM
AL549_06115	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
AL549_06150	COG0714	Associated with various cellular activities
AL549_06155	COG0641	radical SAM
AL549_06160	COG3119	arylsulfatase activity
AL549_06170	COG3119	arylsulfatase activity
AL549_06180	COG0513	Belongs to the DEAD box helicase family
AL549_06185	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AL549_06200	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL549_06225	COG1716	ATPase activity
AL549_06225	COG5001	Diguanylate cyclase
AL549_06230	COG2205	protein histidine kinase activity
AL549_06230	COG0784	Response regulator, receiver
AL549_06235	COG0513	Belongs to the DEAD box helicase family
AL549_06260	COG3005	denitrification pathway
AL549_06265	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL549_06290	COG1879	ABC-type sugar transport system periplasmic component
AL549_06300	COG0210	DNA helicase
AL549_06305	COG1289	transmembrane transporter activity
AL549_06335	COG0789	Transcriptional regulator
AL549_06340	COG4604	ABC transporter, ATP-binding protein
AL549_06345	COG4605	iron ion homeostasis
AL549_06350	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL549_06365	COG0110	maltose O-acetyltransferase activity
AL549_06375	COG3290	protein histidine kinase activity
AL549_06380	COG0471	metal ion transport
AL549_06465	COG4964	Belongs to the GSP D family
AL549_06485	COG0583	DNA-binding transcription factor activity
AL549_06495	COG0419	ATPase involved in DNA repair
AL549_06500	COG0420	3'-5' exonuclease activity
AL549_06515	COG0456	acetyltransferase
AL549_06525	COG0835	chemotaxis
AL549_06525	COG0784	Response regulator, receiver
AL549_06530	COG1609	Transcriptional regulator
AL549_06535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL549_06540	COG1879	ABC-type sugar transport system periplasmic component
AL549_06545	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL549_06550	COG1129	ABC transporter
AL549_06570	COG2315	Protein conserved in bacteria
AL549_06575	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AL549_06590	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AL549_06605	COG1288	antiporter activity
AL549_06615	COG0671	phosphoesterase, PA-phosphatase related
AL549_06630	COG2962	Rard protein
AL549_06655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL549_06660	COG0814	amino acid
AL549_06685	COG3174	membrane
AL549_06690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL549_06720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL549_06725	COG0443	Heat shock 70 kDa protein
AL549_06730	COG1454	alcohol dehydrogenase
AL549_06740	COG2133	pyrroloquinoline quinone binding
AL549_06745	COG1619	proteins homologs of microcin C7 resistance protein MccF
AL549_06760	COG0247	lactate metabolic process
AL549_06770	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL549_06800	COG3059	membrane
AL549_06805	COG4175	Glycine betaine
AL549_06825	COG1012	belongs to the aldehyde dehydrogenase family
AL549_06830	COG1309	transcriptional regulator
AL549_06850	COG1686	Belongs to the peptidase S11 family
AL549_06870	COG1760	l-serine dehydratase
AL549_06885	COG0583	DNA-binding transcription factor activity
AL549_06890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL549_06910	COG3842	ATPase activity
AL549_06920	COG1840	ABC-type Fe3 transport system, periplasmic component
AL549_06925	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AL549_06940	COG2207	Transcriptional regulator
AL549_06940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL549_06945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL549_06970	COG1011	Hydrolase
AL549_06990	COG2171	N-acyltransferase activity
AL549_06995	COG1765	OsmC-like protein
AL549_07000	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL549_07000	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL549_07005	COG3706	GGDEF domain
AL549_07020	COG0840	transmembrane signaling receptor activity
AL549_07040	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL549_07065	COG2084	Dehydrogenase
AL549_07075	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AL549_07085	COG0739	heme binding
AL549_07115	COG0840	transmembrane signaling receptor activity
AL549_07125	COG0366	Alpha amylase catalytic
AL549_07130	COG0589	response to stress
AL549_07135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL549_07140	COG0835	chemotaxis
AL549_07140	COG0784	Response regulator, receiver
AL549_07150	COG0748	coenzyme F420 binding
AL549_07155	COG3721	Heme iron utilization protein
AL549_07165	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AL549_07170	COG0811	peptide transport
AL549_07175	COG0848	biopolymer transport protein
AL549_07185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL549_07190	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AL549_07215	COG3025	triphosphatase activity
AL549_07220	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL549_07230	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AL549_07240	COG1538	Outer membrane efflux protein
AL549_07245	COG0494	nUDIX hydrolase
AL549_07250	COG3151	Protein conserved in bacteria
AL549_07260	COG3150	esterase
AL549_07265	COG0187	DNA topoisomerase II activity
AL549_07275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL549_07280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL549_07285	COG3105	Protein conserved in bacteria
AL549_07290	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL549_07305	COG0723	plastoquinol--plastocyanin reductase activity
AL549_07310	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AL549_07315	COG2857	Cytochrome c1
AL549_07320	COG0625	glutathione transferase activity
AL549_07325	COG2969	positive regulation of protein catabolic process
AL549_07330	COG2823	Periplasmic or secreted lipoprotein
AL549_07335	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL549_07345	COG3107	peptidoglycan biosynthetic process
AL549_07350	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AL549_07365	COG3116	cell division
AL549_07370	COG0768	penicillin binding
AL549_07380	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AL549_07385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL549_07395	COG0772	Belongs to the SEDS family
AL549_07405	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL549_07410	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AL549_07415	COG0849	cell division
AL549_07420	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AL549_07435	COG0653	protein targeting
AL549_07440	COG0494	nUDIX hydrolase
AL549_07450	COG0505	Belongs to the CarA family
AL549_07470	COG0730	response to heat
AL549_07475	COG0583	DNA-binding transcription factor activity
AL549_07480	COG2860	membrane
AL549_07485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL549_07490	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AL549_07495	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL549_07505	COG0493	'glutamate synthase
AL549_07510	COG0069	glutamate synthase activity
AL549_07510	COG0070	glutamate synthase
AL549_07510	COG0067	glutamate synthase
AL549_07520	COG0069	glutamate synthase activity
AL549_07520	COG0070	glutamate synthase
AL549_07520	COG0067	glutamate synthase
AL549_07525	COG1242	4 iron, 4 sulfur cluster binding
AL549_07530	COG2203	Gaf domain
AL549_07530	COG3706	GGDEF domain
AL549_07530	COG4251	negative regulation of phosphorylation
AL549_07530	COG5001	Diguanylate cyclase
AL549_07535	COG5002	protein histidine kinase activity
AL549_07535	COG2198	Histidine kinase
AL549_07535	COG0784	Response regulator, receiver
AL549_07545	COG0745	RESPONSE REGULATOR receiver
AL549_07575	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AL549_07605	COG1115	amino acid carrier protein
AL549_07610	COG3022	response to hydroperoxide
AL549_07615	COG0513	Belongs to the DEAD box helicase family
AL549_07630	COG0716	FMN binding
AL549_07640	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL549_07645	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AL549_07670	COG0667	Aldo Keto reductase
AL549_07695	COG0730	response to heat
AL549_07715	COG1283	sodium-dependent phosphate transmembrane transporter activity
AL549_07720	COG0583	DNA-binding transcription factor activity
AL549_07725	COG0640	Transcriptional regulator
AL549_07735	COG0728	peptidoglycan biosynthetic process
AL549_07740	COG0196	riboflavin kinase activity
AL549_07745	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AL549_07755	COG1047	Peptidyl-prolyl cis-trans
AL549_07770	COG3275	phosphorelay sensor kinase activity
AL549_07775	COG1966	Carbon starvation protein
AL549_07795	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AL549_07800	COG1472	Belongs to the glycosyl hydrolase 3 family
AL549_07805	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL549_07810	COG1605	Chorismate mutase
AL549_07810	COG0287	Prephenate dehydrogenase
AL549_07815	COG0739	heme binding
AL549_07825	COG0488	(ABC) transporter
AL549_07845	COG0077	Prephenate dehydratase
AL549_07845	COG1605	Chorismate mutase
AL549_07850	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL549_07855	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL549_07910	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL549_07925	COG0745	RESPONSE REGULATOR receiver
AL549_07930	COG5002	protein histidine kinase activity
AL549_07940	COG0248	Ppx GppA phosphatase
AL549_07945	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AL549_07950	COG0573	inorganic phosphate transmembrane transporter activity
AL549_07955	COG0581	inorganic phosphate transmembrane transporter activity
AL549_07965	COG0704	Plays a role in the regulation of phosphate uptake
AL549_08000	COG0450	alkyl hydroperoxide reductase
AL549_08005	COG0583	DNA-binding transcription factor activity
AL549_08010	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AL549_08020	COG0517	IMP dehydrogenase activity
AL549_08030	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AL549_08040	COG1862	Preprotein translocase
AL549_08045	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL549_08050	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL549_08065	COG0483	inositol monophosphate 1-phosphatase activity
AL549_08070	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AL549_08085	COG0822	iron-sulfur transferase activity
AL549_08105	COG0633	Ferredoxin
AL549_08110	COG2975	iron-sulfur cluster assembly
AL549_08125	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AL549_08145	COG2976	Protein conserved in bacteria
AL549_08150	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL549_08165	COG2203	Gaf domain
AL549_08165	COG2199	diguanylate cyclase activity
AL549_08180	COG0516	GMP reductase activity
AL549_08180	COG0517	IMP dehydrogenase activity
AL549_08185	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL549_08185	COG0519	Catalyzes the synthesis of GMP from XMP
AL549_08195	COG1584	GPR1 FUN34 yaaH family protein
AL549_08200	COG1115	amino acid carrier protein
AL549_08205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL549_08210	COG0583	DNA-binding transcription factor activity
AL549_08230	COG0009	L-threonylcarbamoyladenylate synthase
AL549_08285	COG2867	negative regulation of translational initiation
AL549_08295	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL549_08300	COG0497	DNA recombination
AL549_08305	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AL549_08310	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AL549_08375	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AL549_08380	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AL549_08385	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AL549_08390	COG0583	DNA-binding transcription factor activity
AL549_08395	COG0590	tRNA wobble adenosine to inosine editing
AL549_08435	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL549_08440	COG2252	PERMEase
AL549_08470	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AL549_08475	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL549_08475	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL549_08500	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AL549_08505	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AL549_08510	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AL549_08515	COG0142	geranyltranstransferase activity
AL549_08525	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AL549_08540	COG0583	DNA-binding transcription factor activity
AL549_08550	COG2363	Small membrane protein
AL549_08565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL549_08570	COG1611	Belongs to the LOG family
AL549_08575	COG3706	GGDEF domain
AL549_08595	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
AL549_08600	COG1464	Belongs to the NlpA lipoprotein family
AL549_08605	COG2011	ABC-type metal ion transport system permease component
AL549_08610	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL549_08615	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL549_08625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL549_08625	COG1263	PTS System
AL549_08630	COG0366	Alpha amylase catalytic
AL549_08665	COG1686	Belongs to the peptidase S11 family
AL549_08670	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AL549_08675	COG0772	Belongs to the SEDS family
AL549_08680	COG0768	penicillin binding
AL549_08690	COG0799	negative regulation of ribosome biogenesis
AL549_08695	COG1466	dna polymerase III delta subunit
AL549_08700	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AL549_08710	COG2888	peptidyl-tyrosine sulfation
AL549_08720	COG4535	Mg2 and Co2 transporter CorC
AL549_08725	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AL549_08730	COG1702	phosphate starvation-inducible protein PhoH
AL549_08740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL549_08835	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AL549_08845	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AL549_08855	COG2890	protein-(glutamine-N5) methyltransferase activity
AL549_08860	COG3094	Invasion gene expression up-regulator, SirB
AL549_08865	COG2912	Transglutaminase-like superfamily
AL549_08885	COG1187	pseudouridine synthase activity
AL549_08890	COG2840	Smr protein MutS2
AL549_08900	COG3735	TraB family
AL549_08915	COG2608	mercury ion transmembrane transporter activity
AL549_08915	COG2217	Heavy metal translocating P-type atpase
AL549_08930	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL549_08960	COG3385	transposase activity
AL549_08980	COG0784	Response regulator, receiver
AL549_08980	COG0835	chemotaxis
AL549_08985	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL549_08990	COG1815	bacterial-type flagellum-dependent cell motility
AL549_08995	COG1558	bacterial-type flagellum-dependent cell motility
AL549_09000	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AL549_09005	COG1749	Flagellar hook protein flgE
AL549_09010	COG4787	bacterial-type flagellum-dependent cell motility
AL549_09015	COG4786	Flagellar basal body rod
AL549_09030	COG1705	Flagellar rod assembly protein muramidase FlgJ
AL549_09030	COG3951	Flagellar rod assembly protein muramidase FlgJ
AL549_09040	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL549_09045	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL549_09055	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL549_09060	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL549_09065	COG2190	(PTS) system
AL549_09070	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL549_09075	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL549_09080	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL549_09085	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AL549_09110	COG0330	HflC and HflK could
AL549_09115	COG3118	belongs to the thioredoxin family
AL549_09120	COG0300	oxidoreductase activity
AL549_09125	COG1090	epimerase
AL549_09150	COG0622	Phosphoesterase
AL549_09170	COG3710	Transcriptional regulator
AL549_09185	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AL549_09190	COG0840	transmembrane signaling receptor activity
AL549_09195	COG3104	oligopeptide transport
AL549_09205	COG0367	asparagine synthase
AL549_09210	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL549_09210	COG4651	solute:proton antiporter activity
AL549_09215	COG1846	Transcriptional regulator
AL549_09215	COG1940	carbohydrate kinase activity
AL549_09220	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AL549_09225	COG2190	(PTS) system
AL549_09225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL549_09225	COG1263	PTS System
AL549_09230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL549_09245	COG0716	FMN binding
AL549_09255	COG0596	Alpha beta hydrolase
AL549_09260	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AL549_09265	COG0033	Phosphoglucomutase
AL549_09270	COG2964	Protein conserved in bacteria
AL549_09275	COG0251	oxidation-reduction process
AL549_09285	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL549_09295	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AL549_09305	COG2009	succinate dehydrogenase
AL549_09310	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AL549_09315	COG1053	succinate dehydrogenase
AL549_09325	COG0567	Dehydrogenase, E1 component
AL549_09330	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL549_09345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL549_09355	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AL549_09365	COG1918	ferrous iron import across plasma membrane
AL549_09370	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AL549_09390	COG3102	Protein conserved in bacteria
AL549_09395	COG0788	formyltetrahydrofolate deformylase activity
AL549_09405	COG1199	ATP-dependent helicase activity
AL549_09410	COG1214	PFAM Peptidase M22, glycoprotease
AL549_09425	COG0596	Alpha beta hydrolase
AL549_09430	COG0318	PFAM AMP-dependent synthetase and ligase
AL549_09435	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AL549_09445	COG2894	cell division
AL549_09460	COG2951	lytic endotransglycosylase activity
AL549_09470	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL549_09480	COG0745	RESPONSE REGULATOR receiver
AL549_09485	COG5002	protein histidine kinase activity
AL549_09500	COG1028	Short-chain dehydrogenase reductase Sdr
AL549_09510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL549_09535	COG2986	histidine ammonia-lyase
AL549_09540	COG1216	Glycosyl transferase, family 2
AL549_09550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL549_09560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL549_09565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL549_09615	COG0745	RESPONSE REGULATOR receiver
AL549_09640	COG3842	ATPase activity
AL549_09645	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL549_09650	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL549_09655	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL549_09665	COG2204	response regulator
AL549_09670	COG4191	Histidine kinase
AL549_09690	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AL549_09695	COG0776	regulation of translation
AL549_09700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL549_09705	COG1555	photosystem II stabilization
AL549_09725	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AL549_09730	COG0436	Aminotransferase
AL549_09735	COG1169	isochorismate synthase
AL549_09750	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AL549_09755	COG1441	menaquinone biosynthetic process
AL549_09760	COG0318	PFAM AMP-dependent synthetase and ligase
AL549_09820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL549_09825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL549_09840	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL549_09845	COG1522	sequence-specific DNA binding
AL549_09855	COG1946	Acyl-CoA thioesterase
AL549_09860	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AL549_09875	COG5001	Diguanylate cyclase
AL549_09915	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL549_09930	COG3139	Protein of unknown function (DUF1315)
AL549_09935	COG0252	asparaginase activity
AL549_09940	COG0616	signal peptide processing
AL549_09945	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL549_09945	COG1902	pentaerythritol trinitrate reductase activity
AL549_09950	COG0778	Nitroreductase
AL549_09955	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL549_09960	COG0123	including yeast histone deacetylase and acetoin utilization protein
AL549_09970	COG0745	RESPONSE REGULATOR receiver
AL549_09970	COG3706	GGDEF domain
AL549_09975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL549_09985	COG2731	YhcH YjgK YiaL family protein
AL549_09990	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL549_09995	COG0569	domain protein
AL549_10005	COG3083	sulfuric ester hydrolase activity
AL549_10015	COG3081	Nucleoid-associated protein
AL549_10030	COG1757	Na H antiporter
AL549_10035	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL549_10045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL549_10050	COG2095	MarC family integral membrane protein
AL549_10055	COG1454	alcohol dehydrogenase
AL549_10055	COG1012	belongs to the aldehyde dehydrogenase family
AL549_10060	COG1028	Short-chain dehydrogenase reductase Sdr
AL549_10075	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AL549_10085	COG2056	Na+-H+ antiporter family
AL549_10090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL549_10095	COG2885	chlorophyll binding
AL549_10105	COG0346	lactoylglutathione lyase activity
AL549_10110	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AL549_10120	COG4659	FMN binding
AL549_10130	COG4656	Part of a membrane complex involved in electron transport
AL549_10165	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AL549_10175	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL549_10185	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AL549_10190	COG0314	molybdopterin synthase activity
AL549_10200	COG0601	transmembrane transport
AL549_10205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL549_10210	COG0444	Belongs to the ABC transporter superfamily
AL549_10220	COG0435	Glutathione S-transferase
AL549_10230	COG2350	Protein conserved in bacteria
AL549_10235	COG1607	acyl-coa hydrolase
AL549_10250	COG1301	dicarboxylic acid transport
AL549_10265	COG0135	phosphoribosylanthranilate isomerase activity
AL549_10265	COG0134	indole-3-glycerol-phosphate synthase activity
AL549_10275	COG0512	Glutamine amidotransferase of anthranilate synthase
AL549_10280	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AL549_10290	COG0613	PHP domain protein
AL549_10295	COG0009	L-threonylcarbamoyladenylate synthase
AL549_10325	COG5001	Diguanylate cyclase
AL549_10330	COG0417	DNA replication proofreading
AL549_10335	COG2197	response regulator
AL549_10405	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL549_10410	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL549_10445	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AL549_10450	COG0437	4 iron, 4 sulfur cluster binding
AL549_10455	COG3301	Polysulphide reductase, NrfD
AL549_10460	COG1138	Cytochrome C-type biogenesis protein
AL549_10465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL549_10470	COG4235	cytochrome complex assembly
AL549_10470	COG3088	subunit of a heme lyase
AL549_10485	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL549_10485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL549_10490	COG0489	protein tyrosine kinase activity
AL549_10510	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AL549_10515	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AL549_10520	COG0659	secondary active sulfate transmembrane transporter activity
AL549_10525	COG1530	ribonuclease E activity
AL549_10540	COG1399	metal-binding, possibly nucleic acid-binding protein
AL549_10555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL549_10585	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AL549_10600	COG0084	hydrolase, TatD family'
AL549_10605	COG1263	PTS System
AL549_10605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL549_10615	COG0733	neurotransmitter:sodium symporter activity
AL549_10625	COG4667	esterase of the alpha-beta hydrolase superfamily
AL549_10630	COG0469	pyruvate kinase activity
AL549_10635	COG1940	carbohydrate kinase activity
AL549_10640	COG0784	Response regulator, receiver
AL549_10640	COG0835	chemotaxis
AL549_10645	COG0587	DNA-directed DNA polymerase activity
AL549_10660	COG1028	Short-chain dehydrogenase reductase Sdr
AL549_10665	COG0616	signal peptide processing
AL549_10675	COG0539	negative regulation of cytoplasmic translation
AL549_10685	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AL549_10690	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AL549_10695	COG0284	orotidine-5'-phosphate decarboxylase activity
AL549_10700	COG4174	ABC transporter (Permease)
AL549_10705	COG4239	(ABC) transporter, permease
AL549_10710	COG4166	transmembrane transport
AL549_10715	COG0444	Belongs to the ABC transporter superfamily
AL549_10720	COG4608	Belongs to the ABC transporter superfamily
AL549_10760	COG2989	Protein conserved in bacteria
AL549_10765	COG3108	Peptidase M15
AL549_10770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL549_10800	COG0583	DNA-binding transcription factor activity
AL549_10810	COG0686	Belongs to the AlaDH PNT family
AL549_10830	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AL549_10840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL549_10850	COG0156	8-amino-7-oxononanoate synthase activity
AL549_10865	COG0501	Belongs to the peptidase M48B family
AL549_10875	COG1028	Short-chain dehydrogenase reductase Sdr
AL549_10890	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL549_10910	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AL549_10930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL549_10935	COG2916	Histone family protein nucleoid-structuring protein H-NS
AL549_10940	COG1757	Na H antiporter
AL549_10955	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL549_10960	COG0131	Imidazoleglycerol-phosphate dehydratase
AL549_10960	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL549_10965	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AL549_10985	COG3012	SEC-C Motif Domain Protein
AL549_10990	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AL549_10995	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL549_11000	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL549_11010	COG1435	thymidine kinase activity
AL549_11020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL549_11025	COG0583	DNA-binding transcription factor activity
AL549_11045	COG2116	formate transmembrane transporter activity
AL549_11050	COG0390	transport system, permease component
AL549_11055	COG4459	periplasmic nitrate reductase
AL549_11060	COG3005	denitrification pathway
AL549_11095	COG1227	inorganic diphosphatase activity
AL549_11110	COG4172	Belongs to the ABC transporter superfamily
AL549_11120	COG4171	peptide transport system, permease
AL549_11125	COG4168	peptide transport system, permease
AL549_11135	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AL549_11140	COG1842	Phage shock protein A
AL549_11150	COG1983	PspC domain protein
AL549_11170	COG2818	Glycosylase
AL549_11175	COG0626	cystathionine gamma-synthase activity
AL549_11185	COG0733	neurotransmitter:sodium symporter activity
AL549_11195	COG0564	pseudouridine synthase activity
AL549_11205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL549_11210	COG1151	hydroxylamine reductase activity
AL549_11215	COG3604	Transcriptional regulator
AL549_11220	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AL549_11225	COG4136	ATPase activity
AL549_11230	COG4135	transport system, permease component
AL549_11235	COG4134	Bacterial extracellular solute-binding protein
AL549_11245	COG3313	Fe-S protein
AL549_11275	COG2205	protein histidine kinase activity
AL549_11290	COG1061	Type III restriction enzyme res subunit
AL549_11300	COG2814	Major facilitator Superfamily
AL549_11315	COG0702	epimerase
AL549_11320	COG1136	(ABC) transporter
AL549_11355	COG2985	domain, Protein
AL549_11355	COG3273	potassium ion transport
AL549_11360	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL549_11365	COG1979	alcohol dehydrogenase
AL549_11370	COG1737	Transcriptional regulator
AL549_11375	COG0076	glutamate decarboxylase activity
AL549_11385	COG2431	L-lysine efflux transmembrane transporter activity
AL549_11395	COG3070	regulator of competence-specific genes
AL549_11410	COG5002	protein histidine kinase activity
AL549_11410	COG5002	protein histidine kinase activity
AL549_11420	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AL549_11425	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AL549_11430	COG4988	ABC transporter
AL549_11435	COG0492	ferredoxin-NADP+ reductase activity
AL549_11455	COG3706	GGDEF domain
AL549_11455	COG0745	RESPONSE REGULATOR receiver
AL549_11460	COG0471	metal ion transport
AL549_11465	COG2949	membrane
AL549_11470	COG0281	malic enzyme
AL549_11475	COG1643	Atp-dependent helicase
AL549_11500	COG1346	cytolysis
AL549_11505	COG1380	Effector of murein hydrolase LrgA
AL549_11510	COG2925	Exonuclease
AL549_11560	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AL549_11590	COG1451	nucleotide metabolic process
AL549_11605	COG3063	Type IV pilus biogenesis stability protein PilW
AL549_11615	COG0737	Belongs to the 5'-nucleotidase family
AL549_11620	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL549_11630	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AL549_11640	COG0625	glutathione transferase activity
AL549_11675	COG3706	GGDEF domain
AL549_11675	COG0745	RESPONSE REGULATOR receiver
AL549_11680	COG1278	Cold shock
AL549_11695	COG0584	glycerophosphoryl diester phosphodiesterase
AL549_11700	COG1349	DNA-binding transcription factor activity
AL549_11710	COG0395	ABC-type sugar transport system, permease component
AL549_11715	COG1175	transmembrane transport
AL549_11720	COG1653	transport
AL549_11735	COG0730	response to heat
AL549_11740	COG2197	response regulator
AL549_11785	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AL549_11790	COG0732	type I restriction modification DNA specificity domain
AL549_11800	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AL549_11805	COG0372	Belongs to the citrate synthase family
AL549_11810	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL549_11815	COG2828	Protein conserved in bacteria
AL549_11845	COG0561	phosphatase activity
AL549_11850	COG0602	queuosine metabolic process
AL549_11860	COG3706	GGDEF domain
AL549_11885	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AL549_11895	COG1254	Belongs to the acylphosphatase family
AL549_11900	COG2920	part of a sulfur-relay system
AL549_11910	COG0670	Belongs to the BI1 family
AL549_11915	COG1126	abc transporter atp-binding protein
AL549_11920	COG0765	amino acid transport
AL549_11925	COG4597	amino acid ABC transporter
AL549_11930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL549_11940	COG0437	4 iron, 4 sulfur cluster binding
AL549_11945	COG0348	domain, Protein
AL549_11950	COG0204	Acyl-transferase
AL549_11955	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AL549_11970	COG1115	amino acid carrier protein
AL549_11995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL549_12010	COG3290	protein histidine kinase activity
AL549_12015	COG4565	transcriptional regulatory protein
AL549_12020	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AL549_12025	COG0363	glucosamine-6-phosphate deaminase activity
AL549_12030	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AL549_12060	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL549_12070	COG0438	transferase activity, transferring glycosyl groups
AL549_12085	COG0110	maltose O-acetyltransferase activity
AL549_12115	COG2204	response regulator
AL549_12145	COG1366	Belongs to the anti-sigma-factor antagonist family
AL549_12150	COG1793	dna ligase
AL549_12155	COG3706	GGDEF domain
AL549_12165	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL549_12180	COG2996	Protein conserved in bacteria
AL549_12190	COG3008	intermembrane lipid transfer
AL549_12195	COG2995	paraquat-inducible protein a
AL549_12200	COG1132	(ABC) transporter
AL549_12205	COG1956	GAF domain-containing protein
AL549_12225	COG0308	aminopeptidase N
AL549_12230	COG2902	Dehydrogenase
AL549_12245	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AL549_12245	COG0116	Belongs to the methyltransferase superfamily
AL549_12275	COG1067	ATP-dependent peptidase activity
AL549_12280	COG3120	sequence-specific DNA binding
AL549_12315	COG3278	Belongs to the heme-copper respiratory oxidase family
AL549_12330	COG2010	Cytochrome c
AL549_12340	COG2217	Heavy metal translocating P-type atpase
AL549_12355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL549_12360	COG0589	response to stress
AL549_12365	COG0037	tRNA processing
AL549_12370	COG3385	transposase activity
AL549_12380	COG2992	FlgJ-related protein
AL549_12395	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL549_12400	COG1177	transmembrane transport
AL549_12405	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL549_12410	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL549_12415	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL549_12420	COG0004	ammonium transporteR
AL549_12455	COG0437	4 iron, 4 sulfur cluster binding
AL549_12460	COG3383	formate dehydrogenase (NAD+) activity
AL549_12460	COG0243	molybdopterin cofactor binding
AL549_12490	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL549_12500	COG0488	(ABC) transporter
AL549_12515	COG3852	Histidine kinase
AL549_12520	COG2204	response regulator
AL549_12530	COG4662	Binding-protein-dependent transport system inner membrane component
AL549_12535	COG3842	ATPase activity
AL549_12540	COG0746	molybdenum cofactor guanylyltransferase activity
AL549_12570	COG0840	transmembrane signaling receptor activity
AL549_12575	COG0791	NLP P60 protein
AL549_12585	COG3706	GGDEF domain
AL549_12605	COG0307	riboflavin synthase, alpha
AL549_12610	COG0534	Mate efflux family protein
AL549_12640	COG2801	Transposase and inactivated derivatives
AL549_12685	COG2801	Transposase and inactivated derivatives
AL549_12765	COG1942	4-Oxalocrotonate Tautomerase
AL549_12805	COG0625	glutathione transferase activity
AL549_12865	COG1942	4-Oxalocrotonate Tautomerase
AL549_12900	COG0625	glutathione transferase activity
AL549_13050	COG4628	conserved protein (DUF2132)
AL549_13320	COG2801	Transposase and inactivated derivatives
AL549_13485	COG3738	Protein conserved in bacteria
AL549_13560	COG0346	lactoylglutathione lyase activity
AL549_13655	COG1943	Transposase
AL549_13705	COG1942	4-Oxalocrotonate Tautomerase
AL549_13825	COG4115	mRNA cleavage
AL549_13830	COG2161	toxin-antitoxin pair type II binding
AL549_13840	COG1280	lysine exporter protein (LysE YggA)
AL549_13885	COG4326	sporulation control protein
AL549_13895	COG1228	amidohydrolase
AL549_13920	COG5640	endopeptidase activity
AL549_13925	COG2020	methyltransferase activity
AL549_13930	COG0247	lactate metabolic process
AL549_13930	COG0277	FAD linked oxidase domain protein
AL549_13945	COG2885	chlorophyll binding
AL549_13995	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AL549_14000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL549_14000	COG0072	phenylalanine-tRNA ligase activity
AL549_14010	COG0745	RESPONSE REGULATOR receiver
AL549_14010	COG3706	GGDEF domain
AL549_14065	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AL549_14075	COG0010	Belongs to the arginase family
AL549_14080	COG0840	transmembrane signaling receptor activity
AL549_14095	COG2814	Major facilitator Superfamily
AL549_14105	COG3279	Response regulator of the LytR AlgR family
AL549_14115	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AL549_14140	COG1643	Atp-dependent helicase
AL549_14150	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AL549_14190	COG2894	cell division
AL549_14200	COG4964	Belongs to the GSP D family
AL549_14250	COG3706	GGDEF domain
AL549_14265	COG0443	Heat shock 70 kDa protein
AL549_14280	COG2169	Transcriptional regulator
AL549_14280	COG1917	Cupin 2, conserved barrel domain protein
AL549_14320	COG0297	glycogen (starch) synthase activity
AL549_14320	COG0438	transferase activity, transferring glycosyl groups
AL549_14325	COG0438	transferase activity, transferring glycosyl groups
AL549_14350	COG1596	polysaccharide export
AL549_14365	COG1115	amino acid carrier protein
AL549_14370	COG1132	(ABC) transporter
AL549_14375	COG1132	(ABC) transporter
AL549_14390	COG0783	Belongs to the Dps family
AL549_14405	COG0814	amino acid
AL549_14410	COG1597	lipid kinase activity
AL549_14420	COG4667	esterase of the alpha-beta hydrolase superfamily
AL549_14425	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL549_14440	COG0583	DNA-binding transcription factor activity
AL549_14445	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL549_14450	COG1328	CTP reductase activity
AL549_14455	COG5001	Diguanylate cyclase
AL549_14455	COG3300	MHYT domain
AL549_14470	COG2199	diguanylate cyclase activity
AL549_14470	COG2200	EAL domain
AL549_14475	COG3706	GGDEF domain
AL549_14485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL549_14485	COG4191	Histidine kinase
AL549_14490	COG0471	metal ion transport
AL549_14505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL549_14510	COG3283	Transcriptional regulator of aromatic amino acids metabolism
AL549_14515	COG3768	UPF0283 membrane protein
AL549_14520	COG3106	COG3106 Predicted ATPase
AL549_14535	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AL549_14555	COG0494	nUDIX hydrolase
AL549_14560	COG0814	amino acid
AL549_14565	COG1760	l-serine dehydratase
AL549_14570	COG2200	EAL domain
AL549_14580	COG0720	synthase
AL549_14585	COG0840	transmembrane signaling receptor activity
AL549_14600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL549_14615	COG2770	Histidine kinase
AL549_14615	COG3437	response regulator, receiver
AL549_14620	COG1448	Aminotransferase
AL549_14640	COG0840	transmembrane signaling receptor activity
AL549_14645	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL549_14650	COG1846	Transcriptional regulator
AL549_14675	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL549_14690	COG3385	transposase activity
AL549_14700	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL549_14710	COG0653	protein targeting
AL549_14720	COG0745	RESPONSE REGULATOR receiver
AL549_14720	COG3706	GGDEF domain
AL549_14725	COG0366	Alpha amylase catalytic
AL549_14735	COG4120	Belongs to the binding-protein-dependent transport system permease family
AL549_14745	COG3092	negative regulation of chromosome organization
AL549_14755	COG0857	belongs to the CobB CobQ family
AL549_14755	COG0280	phosphate acetyltransferase
AL549_14765	COG0583	DNA-binding transcription factor activity
AL549_14790	COG1032	radical SAM domain protein
AL549_14810	COG2207	Transcriptional regulator
AL549_14825	COG0861	Integral membrane protein TerC family
AL549_14830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL549_14835	COG0840	transmembrane signaling receptor activity
AL549_14840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL549_14855	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AL549_14905	COG0784	Response regulator, receiver
AL549_14905	COG2205	protein histidine kinase activity
AL549_14915	COG0754	glutathionylspermidine amidase activity
AL549_14925	COG3766	membrane
AL549_14940	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AL549_14945	COG2885	chlorophyll binding
AL549_14950	COG0823	Involved in the tonB-independent uptake of proteins
AL549_14965	COG0811	peptide transport
AL549_14970	COG0824	Thioesterase
AL549_14980	COG4890	Cyd operon protein YbgT
AL549_14985	COG1294	oxidase, subunit
AL549_14990	COG1271	oxidase subunit
AL549_14995	COG2255	four-way junction helicase activity
AL549_15005	COG0840	transmembrane signaling receptor activity
AL549_15025	COG4106	trans-aconitate 2-methyltransferase activity
AL549_15035	COG4067	protein conserved in archaea
AL549_15035	COG0189	ligase activity
AL549_15065	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AL549_15080	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL549_15085	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AL549_15090	COG0745	RESPONSE REGULATOR receiver
AL549_15095	COG3381	protein complex oligomerization
AL549_15105	COG3070	regulator of competence-specific genes
AL549_15125	COG0297	glycogen (starch) synthase activity
AL549_15130	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AL549_15135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL549_15145	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AL549_15160	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AL549_15165	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AL549_15170	COG0542	response to heat
AL549_15180	COG1278	Cold shock
AL549_15200	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL549_15205	COG1199	ATP-dependent helicase activity
AL549_15215	COG3923	Primosomal replication protein n
AL549_15225	COG0840	transmembrane signaling receptor activity
AL549_15230	COG0708	Exodeoxyribonuclease III
AL549_15245	COG4215	(ABC) transporter
AL549_15270	COG1882	Formate acetyltransferase
AL549_15285	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL549_15300	COG2766	serine protein kinase
AL549_15305	COG2718	Belongs to the UPF0229 family
AL549_15310	COG2719	SpoVR family
AL549_15315	COG2199	diguanylate cyclase activity
AL549_15320	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AL549_15330	COG1663	tetraacyldisaccharide 4'-kinase activity
AL549_15340	COG2333	competence protein COMEC
AL549_15340	COG0658	competence protein
AL549_15350	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL549_15360	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL549_15370	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AL549_15385	COG1252	NADH dehydrogenase
AL549_15415	COG0537	adenosine 5'-monophosphoramidase activity
AL549_15440	COG4109	DRTGG domain
AL549_15445	COG3706	GGDEF domain
AL549_15450	COG1982	Orn Lys Arg decarboxylase major
AL549_15455	COG0531	amino acid
AL549_15460	COG3710	Transcriptional regulator
AL549_15480	COG2203	Gaf domain
AL549_15480	COG2199	diguanylate cyclase activity
AL549_15485	COG2239	Acts as a magnesium transporter
AL549_15515	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL549_15570	COG2226	methyltransferase
AL549_15585	COG1785	Belongs to the alkaline phosphatase family
AL549_15595	COG0346	lactoylglutathione lyase activity
AL549_15605	COG2983	Belongs to the UPF0260 family
AL549_15620	COG0745	RESPONSE REGULATOR receiver
AL549_15625	COG2205	protein histidine kinase activity
AL549_15645	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AL549_15660	COG0745	RESPONSE REGULATOR receiver
AL549_15665	COG0583	DNA-binding transcription factor activity
AL549_15670	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AL549_15675	COG1286	toxin biosynthetic process
AL549_15680	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AL549_15685	COG0285	dihydrofolate synthase activity
AL549_15705	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL549_15715	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL549_15720	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AL549_15720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL549_15730	COG3101	peptidyl-lysine hydroxylation
AL549_15735	COG2860	membrane
AL549_15740	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AL549_15745	COG2890	protein-(glutamine-N5) methyltransferase activity
AL549_15750	COG2840	Smr protein MutS2
AL549_15755	COG2062	phosphohistidine phosphatase, SixA
AL549_15760	COG1025	Belongs to the peptidase M16 family
AL549_15765	COG1024	Enoyl-CoA hydratase
AL549_15765	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL549_15785	COG2067	long-chain fatty acid transport protein
AL549_15790	COG2067	long-chain fatty acid transport protein
AL549_15795	COG2853	Lipoprotein
AL549_15805	COG3088	subunit of a heme lyase
AL549_15805	COG4235	cytochrome complex assembly
AL549_15810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL549_15815	COG1138	Cytochrome C-type biogenesis protein
AL549_15825	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL549_15830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL549_15835	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL549_15840	COG4133	protoheme IX ABC transporter activity
AL549_15850	COG0835	chemotaxis
AL549_15860	COG1192	Involved in chromosome partitioning
AL549_15865	COG2201	protein-glutamate methylesterase activity
AL549_15870	COG0643	Histidine kinase
AL549_15870	COG2198	Histidine kinase
AL549_15875	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AL549_15890	COG0455	bacterial-type flagellum organization
AL549_15910	COG1684	flagellar biosynthetic protein fliR
AL549_15915	COG1987	bacterial-type flagellum assembly
AL549_15965	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL549_15975	COG1677	Flagellar hook-basal body complex protein FliE
AL549_15980	COG2204	response regulator
AL549_15985	COG4191	Histidine kinase
AL549_15990	COG2204	response regulator
AL549_15995	COG1516	flagellar protein fliS
AL549_16005	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AL549_16010	COG1334	flagellar protein FlaG
AL549_16015	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL549_16020	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL549_16025	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL549_16030	COG2837	iron assimilation
AL549_16055	COG1393	Belongs to the ArsC family
AL549_16075	COG3385	transposase activity
AL549_16085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL549_16090	COG2716	regulation of RNA biosynthetic process
AL549_16095	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL549_16110	COG4783	chaperone-mediated protein folding
AL549_16115	COG1393	Belongs to the ArsC family
AL549_16135	COG2233	PERMEase
AL549_16140	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AL549_16150	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AL549_16155	COG0121	glutamine amidotransferase
AL549_16165	COG1960	acyl-CoA dehydrogenase activity
AL549_16190	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL549_16200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL549_16210	COG2226	methyltransferase
AL549_16215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL549_16220	COG1388	LysM domain
AL549_16220	COG0741	lytic transglycosylase activity
AL549_16230	COG3021	interspecies interaction between organisms
AL549_16235	COG0347	Belongs to the P(II) protein family
AL549_16245	COG0037	tRNA processing
AL549_16255	COG0587	DNA-directed DNA polymerase activity
AL549_16285	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AL549_16290	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL549_16300	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AL549_16305	COG0575	Belongs to the CDS family
AL549_16315	COG0233	cytoplasmic translational termination
AL549_16335	COG0024	Methionine aminopeptidase
AL549_16340	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AL549_16355	COG3098	single-species biofilm formation
AL549_16395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL549_16415	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AL549_16425	COG0254	rRNA binding
AL549_16430	COG1720	tRNA m6t6A37 methyltransferase activity
AL549_16455	COG0733	neurotransmitter:sodium symporter activity
AL549_16470	COG0514	ATP-dependent DNA helicase (RecQ)
AL549_16480	COG0745	RESPONSE REGULATOR receiver
AL549_16480	COG3706	GGDEF domain
AL549_16490	COG1477	protein flavinylation
AL549_16525	COG0271	Belongs to the BolA IbaG family
AL549_16545	COG2211	Major facilitator Superfamily
AL549_16555	COG1595	DNA-templated transcription, initiation
AL549_16565	COG3248	Nucleoside-binding outer membrane protein
AL549_16570	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AL549_16575	COG0693	protein deglycase activity
AL549_16580	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL549_16585	COG2166	iron-sulfur cluster assembly
AL549_16590	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AL549_16595	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AL549_16615	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AL549_16620	COG1074	ATP-dependent DNA helicase activity
AL549_16625	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AL549_16630	COG3083	sulfuric ester hydrolase activity
AL549_16645	COG3141	response to X-ray
AL549_16650	COG2171	N-acyltransferase activity
AL549_16655	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL549_16665	COG1349	DNA-binding transcription factor activity
AL549_16670	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL549_16685	COG0569	domain protein
AL549_16685	COG0189	ligase activity
AL549_16705	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL549_16715	COG0840	transmembrane signaling receptor activity
AL549_16720	COG2017	converts alpha-aldose to the beta-anomer
AL549_16735	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL549_16740	COG1609	Transcriptional regulator
AL549_16750	COG3250	beta-galactosidase activity
AL549_16755	COG2731	YhcH YjgK YiaL family protein
AL549_16760	COG0531	amino acid
AL549_16765	COG0531	amino acid
AL549_16770	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AL549_16770	COG3408	Glycogen debranching enzyme
AL549_16780	COG0583	DNA-binding transcription factor activity
AL549_16785	COG2059	Chromate
AL549_16835	COG4964	Belongs to the GSP D family
AL549_16870	COG1022	Amp-dependent synthetase and ligase
AL549_16875	COG0583	DNA-binding transcription factor activity
AL549_16880	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL549_16895	COG3447	MASE1 domain protein
AL549_16895	COG5002	protein histidine kinase activity
AL549_16895	COG5001	Diguanylate cyclase
AL549_16900	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AL549_16910	COG0560	Phosphoserine phosphatase
AL549_16935	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AL549_16940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL549_16945	COG0084	hydrolase, TatD family'
AL549_16955	COG3706	GGDEF domain
AL549_16965	COG0456	acetyltransferase
AL549_16975	COG3153	acetyltransferase
AL549_17000	COG0534	Mate efflux family protein
AL549_17010	COG4785	May be involved in cell division
AL549_17060	COG0195	Participates in both transcription termination and antitermination
AL549_17080	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL549_17085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL549_17090	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AL549_17095	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL549_17105	COG1534	Rna-binding protein
AL549_17125	COG2027	D-alanyl-D-alanine carboxypeptidase
AL549_17130	COG2832	Protein of unknown function (DUF454)
AL549_17140	COG0739	heme binding
AL549_17155	COG0316	Belongs to the HesB IscA family
AL549_17165	COG0628	permease
AL549_17170	COG2813	Specifically methylates the guanine in position
AL549_17175	COG0784	Response regulator, receiver
AL549_17175	COG2205	protein histidine kinase activity
AL549_17185	COG0601	transmembrane transport
AL549_17190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL549_17195	COG0444	Belongs to the ABC transporter superfamily
AL549_17200	COG4608	Belongs to the ABC transporter superfamily
AL549_17210	COG2971	BadF BadG BcrA BcrD
AL549_17225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL549_17240	COG1840	ABC-type Fe3 transport system, periplasmic component
AL549_17245	COG0004	ammonium transporteR
AL549_17250	COG0347	Belongs to the P(II) protein family
AL549_17260	COG3835	regulator
AL549_17265	COG2610	gluconate transmembrane transporter activity
AL549_17270	COG1929	Belongs to the glycerate kinase type-1 family
AL549_17275	COG1049	propionate catabolic process, 2-methylcitrate cycle
AL549_17280	COG1752	Esterase of the alpha-beta hydrolase superfamily
AL549_17285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL549_17290	COG1643	Atp-dependent helicase
AL549_17300	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AL549_17315	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL549_17330	COG0842	Transport permease protein
AL549_17335	COG1131	(ABC) transporter
AL549_17340	COG0659	secondary active sulfate transmembrane transporter activity
AL549_17345	COG0288	reversible hydration of carbon dioxide
AL549_17360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL549_17365	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL549_17370	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL549_17375	COG2186	Transcriptional regulator
AL549_17380	COG3023	N-Acetylmuramoyl-L-alanine amidase
AL549_17395	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL549_17400	COG1459	type II secretion system
AL549_17420	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AL549_17445	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL549_17450	COG4137	Cytochrome C assembly protein
AL549_17455	COG4536	flavin adenine dinucleotide binding
AL549_17470	COG2918	glutathione biosynthetic process
AL549_17475	COG0612	Peptidase, M16
AL549_17480	COG1238	metal cluster binding
AL549_17490	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AL549_17495	COG5016	pyruvate
AL549_17495	COG0511	ligase activity, forming carbon-carbon bonds
AL549_17550	COG0527	aspartate kinase activity
AL549_17555	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL549_17560	COG2137	regulation of response to DNA damage stimulus
AL549_17575	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AL549_17580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL549_17585	COG1388	LysM domain
AL549_17585	COG4942	peptidase
AL549_17605	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AL549_17630	COG3956	TIGRFAM MazG family protein
AL549_17635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL549_17640	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL549_17645	COG3850	Histidine kinase
AL549_17645	COG2205	protein histidine kinase activity
AL549_17645	COG3437	response regulator, receiver
AL549_17645	COG4999	Histidine kinase
AL549_17665	COG0736	holo-[acyl-carrier-protein] synthase activity
AL549_17675	COG1381	Involved in DNA repair and RecF pathway recombination
AL549_17690	COG0681	Belongs to the peptidase S26 family
AL549_17700	COG3086	response to oxidative stress
AL549_17715	COG1595	DNA-templated transcription, initiation
AL549_17720	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AL549_17735	COG0354	folic acid binding
AL549_17750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL549_17755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL549_17760	COG3079	Belongs to the UPF0149 family
AL549_17765	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AL549_17775	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AL549_17785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL549_17800	COG1279	arginine transmembrane transporter activity
AL549_17805	COG0668	transmembrane transport
AL549_17810	COG0191	fructose-bisphosphate aldolase activity
AL549_17850	COG2356	endonuclease I
AL549_17860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL549_17890	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL549_17895	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AL549_17900	COG0762	integral membrane protein
AL549_17905	COG1872	DUF167
AL549_17920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL549_17950	COG0741	lytic transglycosylase activity
AL549_18055	COG3437	response regulator, receiver
AL549_18065	COG1609	Transcriptional regulator
AL549_18075	COG1486	melibiose metabolic process
AL549_18080	COG1447	Phosphotransferase system cellobiose-specific component IIA
AL549_18090	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL549_18095	COG0726	polysaccharide deacetylase
AL549_18110	COG0795	lipopolysaccharide-transporting ATPase activity
AL549_18115	COG0795	lipopolysaccharide-transporting ATPase activity
AL549_18125	COG2927	DNA polymerase III (CHI subunit)
AL549_18140	COG4269	membrane
AL549_18150	COG0456	acetyltransferase
AL549_18185	COG0251	oxidation-reduction process
AL549_18190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL549_18205	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AL549_18210	COG0312	modulator of DNA gyrase
AL549_18215	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL549_18220	COG3164	Protein of unknown function
AL549_18225	COG1530	ribonuclease E activity
AL549_18235	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AL549_18240	COG1792	Involved in formation and maintenance of cell shape
AL549_18245	COG1077	Cell shape determining protein MreB Mrl
AL549_18290	COG1459	type II secretion system
AL549_18295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL549_18305	COG3409	Peptidoglycan-binding domain 1 protein
AL549_18305	COG3267	Type II secretory pathway component ExeA
AL549_18330	COG2200	EAL domain
AL549_18330	COG2199	diguanylate cyclase activity
AL549_18350	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AL549_18360	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AL549_18365	COG0527	aspartate kinase activity
AL549_18370	COG0646	methionine synthase
AL549_18370	COG1410	methionine synthase
AL549_18380	COG0745	RESPONSE REGULATOR receiver
AL549_18380	COG3706	GGDEF domain
AL549_18480	COG0735	belongs to the Fur family
AL549_18495	COG0432	Pfam Uncharacterised protein family UPF0047
AL549_18505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL549_18510	COG0305	Participates in initiation and elongation during chromosome replication
AL549_18540	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AL549_18545	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AL549_18590	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AL549_18630	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AL549_18640	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AL549_18645	COG0460	homoserine dehydrogenase
AL549_18645	COG0527	aspartate kinase activity
AL549_18650	COG0626	cystathionine gamma-synthase activity
AL549_18660	COG0281	malic enzyme
AL549_18665	COG0254	rRNA binding
AL549_18670	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AL549_18675	COG1609	Transcriptional regulator
AL549_18695	COG1575	Belongs to the MenA family. Type 1 subfamily
AL549_18710	COG1494	fructose-1,6-bisphosphatase
AL549_18740	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL549_18750	COG2906	2 iron, 2 sulfur cluster binding
AL549_18760	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL549_18775	COG2168	tRNA wobble position uridine thiolation
AL549_18785	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AL549_18790	COG2964	Protein conserved in bacteria
AL549_18795	COG0545	Peptidyl-prolyl cis-trans isomerase
AL549_18815	COG1047	Peptidyl-prolyl cis-trans
AL549_18830	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL549_18835	COG0488	(ABC) transporter
AL549_18845	COG0429	hydrolase of the alpha beta-hydrolase fold
AL549_18855	COG3954	Phosphoribulokinase
AL549_18860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL549_18880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL549_18915	COG0557	exoribonuclease II activity
AL549_18920	COG0402	S-adenosylhomocysteine deaminase activity
AL549_18935	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AL549_18940	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AL549_18945	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AL549_18950	COG0330	HflC and HflK could
AL549_18955	COG0330	HflC and HflK could
AL549_18960	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL549_18980	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL549_18985	COG0802	atpase or kinase
AL549_18990	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL549_19065	COG0471	metal ion transport
AL549_19075	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AL549_19080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL549_19095	COG1045	serine acetyltransferase
AL549_19100	COG4942	peptidase
AL549_19125	COG1053	succinate dehydrogenase
AL549_19130	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL549_19140	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AL549_19155	COG1509	lysine 2,3-aminomutase activity
AL549_19160	COG1285	pathogenesis
AL549_19180	COG0534	Mate efflux family protein
AL549_19195	COG3678	ATP-independent chaperone mediated protein folding
AL549_19200	COG0745	RESPONSE REGULATOR receiver
AL549_19205	COG2205	protein histidine kinase activity
AL549_19215	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AL549_19225	COG1027	Aspartate ammonia-lyase
AL549_19230	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL549_19245	COG2095	MarC family integral membrane protein
AL549_19255	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL549_19270	COG0784	Response regulator, receiver
AL549_19270	COG2205	protein histidine kinase activity
AL549_19270	COG2198	Histidine kinase
AL549_19275	COG2814	Major facilitator Superfamily
AL549_19290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL549_19300	COG0511	ligase activity, forming carbon-carbon bonds
AL549_19305	COG0439	Biotin carboxylase
AL549_19310	COG2264	protein methyltransferase activity
AL549_19320	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AL549_19325	COG0840	transmembrane signaling receptor activity
AL549_19330	COG0789	Transcriptional regulator
AL549_19340	COG0151	Belongs to the GarS family
AL549_19355	COG1253	flavin adenine dinucleotide binding
AL549_19360	COG3068	Protein conserved in bacteria
AL549_19365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL549_19370	COG1573	uracil-dna glycosylase
AL549_19395	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AL549_19435	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL549_19475	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AL549_19485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL549_19560	COG4206	TonB-dependent receptor
AL549_19565	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL549_19610	COG1580	Controls the rotational direction of flagella during chemotaxis
AL549_19615	COG0705	Rhomboid family
AL549_19630	COG2177	Part of the ABC transporter FtsEX involved in
AL549_19635	COG2884	Cell division ATP-binding protein ftsE
AL549_19640	COG0552	protein localization to endoplasmic reticulum
AL549_19645	COG0742	ribosomal rna small subunit methyltransferase
AL549_19655	COG2095	MarC family integral membrane protein
AL549_19695	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL549_19700	COG0640	Transcriptional regulator
AL549_19705	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AL549_19710	COG1280	lysine exporter protein (LysE YggA)
AL549_19715	COG2267	carboxylic ester hydrolase activity
AL549_19720	COG0561	phosphatase activity
AL549_19740	COG2200	EAL domain
AL549_19740	COG2199	diguanylate cyclase activity
AL549_19740	COG3287	FIST C domain
AL549_19745	COG1011	Hydrolase
AL549_19765	COG0019	diaminopimelate decarboxylase activity
AL549_19780	COG3072	Adenylate cyclase
AL549_19795	COG2959	enzyme of heme biosynthesis
AL549_19805	COG2081	HI0933 family
AL549_19815	COG1528	Iron-storage protein
AL549_19820	COG0589	response to stress
AL549_19840	COG5002	protein histidine kinase activity
AL549_19840	COG5001	Diguanylate cyclase
AL549_19845	COG1522	sequence-specific DNA binding
AL549_19855	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AL549_19860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL549_19880	COG0800	Aldolase
AL549_19890	COG3265	gluconokinase activity
AL549_19895	COG0129	dihydroxy-acid dehydratase activity
AL549_19900	COG1609	Transcriptional regulator
AL549_19915	COG2815	serine threonine protein kinase
AL549_19915	COG0515	serine threonine protein kinase
AL549_19950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL549_19960	COG4166	transmembrane transport
AL549_19965	COG4172	Belongs to the ABC transporter superfamily
AL549_20005	COG1309	transcriptional regulator
AL549_20010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL549_20015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL549_20020	COG2960	long-chain fatty acid transporting porin activity
AL549_20030	COG0583	DNA-binding transcription factor activity
AL549_20080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL549_20085	COG1739	Uncharacterized protein family UPF0029
AL549_20095	COG0183	Belongs to the thiolase family
AL549_20100	COG0604	alcohol dehydrogenase
AL549_20125	COG2119	membrane
AL549_20145	COG3977	Valine--pyruvate aminotransferase
AL549_20155	COG0071	Belongs to the small heat shock protein (HSP20) family
AL549_20160	COG0187	DNA topoisomerase II activity
AL549_20170	COG0592	DNA-directed DNA polymerase activity
AL549_20190	COG1126	abc transporter atp-binding protein
AL549_20205	COG0706	membrane insertase activity
AL549_20215	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AL549_20230	COG1192	Involved in chromosome partitioning
AL549_20235	COG1475	DNA binding
AL549_20240	COG3312	ion transport
AL549_20255	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AL549_20290	COG0765	amino acid transport
AL549_20300	COG2814	Major facilitator Superfamily
AL549_20305	COG0583	DNA-binding transcription factor activity
AL549_20315	COG0129	dihydroxy-acid dehydratase activity
AL549_20320	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL549_20325	COG3978	acetolactate synthase activity
AL549_20335	COG0606	chelatase, subunit chli
AL549_20345	COG0204	Acyl-transferase
AL549_20350	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL549_20355	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AL549_20365	COG3084	Protein conserved in bacteria
AL549_20370	COG4326	sporulation control protein
AL549_20375	COG1272	protein, Hemolysin III
AL549_20380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL549_20385	COG0569	domain protein
AL549_20400	COG0242	peptide deformylase activity
AL549_20410	COG0758	DNA mediated transformation
AL549_20420	COG0551	DNA topoisomerase type I activity
AL549_20440	COG0408	coproporphyrinogen oxidase activity
AL549_20445	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL549_20455	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AL549_20505	COG2132	Multicopper oxidase
AL549_20525	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL549_20545	COG0006	proline dipeptidase activity
AL549_20545	COG0006	proline dipeptidase activity
AL549_20585	COG0210	DNA helicase
AL549_20590	COG1280	lysine exporter protein (LysE YggA)
AL549_20600	COG2962	Rard protein
AL549_20605	COG0514	ATP-dependent DNA helicase (RecQ)
AL549_20615	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AL549_20630	COG3118	belongs to the thioredoxin family
AL549_20635	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AL549_20745	COG1322	Protein conserved in bacteria
AL549_20755	COG3165	ubiquinone biosynthetic process from chorismate
AL549_20765	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL549_20775	COG0805	protein transport
AL549_20780	COG0084	hydrolase, TatD family'
AL549_20790	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL549_20790	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL549_20810	COG3078	GTPase activator activity
AL549_20820	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL549_20825	COG3300	MHYT domain
AL549_20825	COG5001	Diguanylate cyclase
AL549_20830	COG2204	response regulator
AL549_20835	COG3852	Histidine kinase
AL549_20845	COG0174	glutamine synthetase
AL549_20865	COG1295	ribonuclease BN
AL549_20875	COG0456	acetyltransferase
AL549_20895	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AL549_20900	COG3031	protein transport across the cell outer membrane
AL549_20910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL549_20915	COG1459	type II secretion system
AL549_20920	COG2165	general secretion pathway protein
AL549_20925	COG2165	general secretion pathway protein
AL549_20930	COG2165	general secretion pathway protein
AL549_20935	COG4795	General secretion pathway protein
AL549_20940	COG3156	type II secretion system protein K
AL549_20945	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AL549_20950	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AL549_20960	COG1218	3'(2'),5'-bisphosphate nucleotidase
AL549_20965	COG0494	nUDIX hydrolase
AL549_20980	COG0596	Alpha beta hydrolase
AL549_20990	COG2183	response to ionizing radiation
AL549_21000	COG0745	RESPONSE REGULATOR receiver
AL549_21005	COG2205	protein histidine kinase activity
AL549_21010	COG2233	PERMEase
AL549_21015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AL549_21020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL549_21025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL549_21050	COG0848	biopolymer transport protein
AL549_21055	COG0811	peptide transport
AL549_21060	COG0811	peptide transport
AL549_21070	COG4206	TonB-dependent receptor
AL549_21075	COG4174	ABC transporter (Permease)
AL549_21080	COG4239	(ABC) transporter, permease
AL549_21085	COG0747	negative chemotaxis
AL549_21090	COG0444	Belongs to the ABC transporter superfamily
AL549_21095	COG4608	Belongs to the ABC transporter superfamily
AL549_21125	COG1561	YicC-like family, N-terminal region
AL549_21140	COG1560	Kdo2-lipid A biosynthetic process
AL549_21150	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AL549_21160	COG2003	Belongs to the UPF0758 family
AL549_21195	COG0859	PFAM glycosyl transferase family 9
AL549_21200	COG0463	Glycosyl transferase, family 2
AL549_21205	COG0859	PFAM glycosyl transferase family 9
AL549_21210	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL549_21215	COG3642	lipopolysaccharide core region biosynthetic process
AL549_21220	COG3083	sulfuric ester hydrolase activity
AL549_21235	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AL549_21240	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AL549_21245	COG2089	acid synthase
AL549_21260	COG0673	inositol 2-dehydrogenase activity
AL549_21270	COG1083	cytidylyl-transferase
AL549_21275	COG1028	Short-chain dehydrogenase reductase Sdr
AL549_21290	COG0318	PFAM AMP-dependent synthetase and ligase
AL549_21320	COG1519	Transferase
AL549_21325	COG0859	PFAM glycosyl transferase family 9
AL549_21330	COG1560	Kdo2-lipid A biosynthetic process
AL549_21340	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL549_21375	COG1596	polysaccharide export
AL549_21390	COG3206	protein involved in exopolysaccharide biosynthesis
AL549_21390	COG0489	protein tyrosine kinase activity
AL549_21410	COG3475	LICD family
AL549_21415	COG3475	LICD family
AL549_21430	COG1943	Transposase
AL549_21440	COG1086	Polysaccharide biosynthesis protein
AL549_21470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL549_21485	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AL549_21600	COG0201	protein transport
AL549_21615	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AL549_21640	COG0545	Peptidyl-prolyl cis-trans isomerase
AL549_21645	COG3061	Opacity-associated protein A
AL549_21645	COG3266	domain, Protein
AL549_21655	COG2153	protein acetylation
AL549_21665	COG0737	Belongs to the 5'-nucleotidase family
AL549_21670	COG1648	precorrin-2 dehydrogenase activity
AL549_21670	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL549_21680	COG2895	sulfate adenylyltransferase (ATP) activity
AL549_21685	COG3273	potassium ion transport
AL549_21685	COG0471	metal ion transport
AL549_21710	COG1136	(ABC) transporter
AL549_21710	COG0577	efflux transmembrane transporter activity
AL549_21725	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AL549_21740	COG0729	surface antigen
AL549_21745	COG2911	Protein conserved in bacteria
AL549_21750	COG2105	PFAM AIG2 family protein
AL549_21770	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL549_21775	COG0163	prenyltransferase activity
AL549_21780	COG4143	(ABC) transporter
AL549_21785	COG1178	ABC-type Fe3 transport system permease component
AL549_21795	COG3028	Belongs to the UPF0307 family
AL549_21800	COG0312	modulator of DNA gyrase
AL549_21805	COG2239	Acts as a magnesium transporter
AL549_21810	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL549_21815	COG1660	Displays ATPase and GTPase activities
AL549_21820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL549_21825	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL549_21835	COG1137	ATPase activity
AL549_21840	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AL549_21850	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AL549_21855	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AL549_21855	COG0517	IMP dehydrogenase activity
AL549_21865	COG1127	ABC transporter
AL549_21870	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL549_21875	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL549_21880	COG2854	intermembrane phospholipid transfer
AL549_21890	COG5007	Belongs to the BolA IbaG family
AL549_21900	COG0204	Acyl-transferase
AL549_21905	COG0589	response to stress
AL549_21925	COG0039	L-malate dehydrogenase activity
AL549_21930	COG0142	geranyltranstransferase activity
AL549_21935	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AL549_21945	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AL549_21950	COG2966	Psort location CytoplasmicMembrane, score
AL549_21955	COG3610	response to peptide
AL549_21980	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL549_22015	COG0473	3-isopropylmalate dehydrogenase activity
AL549_22045	COG1022	Amp-dependent synthetase and ligase
AL549_22050	COG0028	Belongs to the TPP enzyme family
AL549_22055	COG0440	acetolactate synthase activity
AL549_22060	COG3706	GGDEF domain
AL549_22070	COG0469	pyruvate kinase activity
AL549_22075	COG1349	DNA-binding transcription factor activity
AL549_22085	COG3722	fumarate hydratase activity
AL549_22095	COG2213	PTS system mannitol-specific
AL549_22095	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL549_22100	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL549_22120	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL549_22130	COG1610	YqeY-like protein
AL549_22135	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AL549_22145	COG0596	Alpha beta hydrolase
AL549_22155	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AL549_22160	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL549_22170	COG0617	tRNA 3'-terminal CCA addition
AL549_22175	COG3267	Type II secretory pathway component ExeA
AL549_22175	COG3409	Peptidoglycan-binding domain 1 protein
AL549_22180	COG4991	sh3 domain protein
AL549_22185	COG0306	phosphate transporter
AL549_22240	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
AL549_22240	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL549_22290	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL549_22315	COG3140	Belongs to the UPF0181 family
AL549_23825	COG2832	Protein of unknown function (DUF454)
AL549_23895	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AL549_23935	COG1040	competence protein