locus-tag	class	description
FORC36_0002	COG0592	DNA-directed DNA polymerase activity
FORC36_0004	COG0187	DNA topoisomerase II activity
FORC36_0005	COG0071	Belongs to the small heat shock protein (HSP20) family
FORC36_0007	COG3977	Valine--pyruvate aminotransferase
FORC36_0011	COG2119	membrane
FORC36_0016	COG0604	alcohol dehydrogenase
FORC36_0017	COG0183	Belongs to the thiolase family
FORC36_0019	COG1739	Uncharacterized protein family UPF0029
FORC36_0020	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC36_0023	COG3335	DDE superfamily endonuclease
FORC36_0025	COG2132	Multicopper oxidase
FORC36_0029	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC36_0033	COG0006	proline dipeptidase activity
FORC36_0033	COG0006	proline dipeptidase activity
FORC36_0041	COG0210	DNA helicase
FORC36_0042	COG1280	lysine exporter protein (LysE YggA)
FORC36_0044	COG2962	Rard protein
FORC36_0045	COG0514	ATP-dependent DNA helicase (RecQ)
FORC36_0047	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FORC36_0050	COG3118	belongs to the thioredoxin family
FORC36_0051	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FORC36_0060	COG1322	Protein conserved in bacteria
FORC36_0062	COG3165	ubiquinone biosynthetic process from chorismate
FORC36_0064	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORC36_0066	COG0805	protein transport
FORC36_0067	COG0084	hydrolase, TatD family'
FORC36_0069	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC36_0069	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC36_0073	COG3078	GTPase activator activity
FORC36_0075	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC36_0077	COG2204	response regulator
FORC36_0078	COG3852	Histidine kinase
FORC36_0080	COG0174	glutamine synthetase
FORC36_0084	COG1295	ribonuclease BN
FORC36_0086	COG0456	acetyltransferase
FORC36_0090	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FORC36_0092	COG3031	protein transport across the cell outer membrane
FORC36_0094	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC36_0095	COG1459	type II secretion system
FORC36_0096	COG2165	general secretion pathway protein
FORC36_0097	COG2165	general secretion pathway protein
FORC36_0098	COG2165	general secretion pathway protein
FORC36_0099	COG4795	General secretion pathway protein
FORC36_0100	COG3156	type II secretion system protein K
FORC36_0101	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FORC36_0102	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FORC36_0104	COG1218	3'(2'),5'-bisphosphate nucleotidase
FORC36_0105	COG0494	nUDIX hydrolase
FORC36_0107	COG1040	competence protein
FORC36_0108	COG0596	Alpha beta hydrolase
FORC36_0110	COG2183	response to ionizing radiation
FORC36_0112	COG0745	RESPONSE REGULATOR receiver
FORC36_0114	COG2233	PERMEase
FORC36_0115	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FORC36_0116	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC36_0117	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC36_0122	COG0848	biopolymer transport protein
FORC36_0123	COG0811	peptide transport
FORC36_0124	COG0811	peptide transport
FORC36_0126	COG4206	TonB-dependent receptor
FORC36_0127	COG4174	ABC transporter (Permease)
FORC36_0128	COG4239	(ABC) transporter, permease
FORC36_0129	COG0747	negative chemotaxis
FORC36_0130	COG0444	Belongs to the ABC transporter superfamily
FORC36_0131	COG4608	Belongs to the ABC transporter superfamily
FORC36_0149	COG0582	viral genome integration into host DNA
FORC36_0150	COG1561	YicC-like family, N-terminal region
FORC36_0153	COG1560	Kdo2-lipid A biosynthetic process
FORC36_0157	COG2003	Belongs to the UPF0758 family
FORC36_0164	COG0859	PFAM glycosyl transferase family 9
FORC36_0165	COG0463	Glycosyl transferase, family 2
FORC36_0166	COG0859	PFAM glycosyl transferase family 9
FORC36_0167	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC36_0168	COG3642	lipopolysaccharide core region biosynthetic process
FORC36_0169	COG3083	sulfuric ester hydrolase activity
FORC36_0173	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FORC36_0173	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC36_0175	COG1216	Glycosyl transferase, family 2
FORC36_0180	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FORC36_0181	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FORC36_0182	COG2089	acid synthase
FORC36_0183	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FORC36_0186	COG1083	cytidylyl-transferase
FORC36_0187	COG1028	Short-chain dehydrogenase reductase Sdr
FORC36_0188	COG0438	transferase activity, transferring glycosyl groups
FORC36_0194	COG1519	Transferase
FORC36_0196	COG1560	Kdo2-lipid A biosynthetic process
FORC36_0198	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC36_0205	COG1596	polysaccharide export
FORC36_0209	COG5433	transposase activity
FORC36_0211	COG1083	cytidylyl-transferase
FORC36_0212	COG2089	acid synthase
FORC36_0217	COG0438	transferase activity, transferring glycosyl groups
FORC36_0220	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FORC36_0221	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC36_0222	COG1051	belongs to the nudix hydrolase family
FORC36_0223	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FORC36_0223	COG0662	Cupin 2, conserved barrel domain protein
FORC36_0226	COG1482	cell wall glycoprotein biosynthetic process
FORC36_0227	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORC36_0228	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FORC36_0251	COG0201	protein transport
FORC36_0254	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FORC36_0259	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC36_0260	COG3061	Opacity-associated protein A
FORC36_0260	COG3266	domain, Protein
FORC36_0262	COG2153	protein acetylation
FORC36_0264	COG0737	Belongs to the 5'-nucleotidase family
FORC36_0265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC36_0265	COG1648	precorrin-2 dehydrogenase activity
FORC36_0267	COG2895	sulfate adenylyltransferase (ATP) activity
FORC36_0268	COG3273	potassium ion transport
FORC36_0268	COG0471	metal ion transport
FORC36_0273	COG1136	(ABC) transporter
FORC36_0273	COG0577	efflux transmembrane transporter activity
FORC36_0277	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FORC36_0280	COG0729	surface antigen
FORC36_0281	COG2911	Protein conserved in bacteria
FORC36_0282	COG2105	PFAM AIG2 family protein
FORC36_0286	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC36_0287	COG0163	prenyltransferase activity
FORC36_0288	COG4143	(ABC) transporter
FORC36_0289	COG1178	ABC-type Fe3 transport system permease component
FORC36_0291	COG3028	Belongs to the UPF0307 family
FORC36_0292	COG0312	modulator of DNA gyrase
FORC36_0293	COG2239	Acts as a magnesium transporter
FORC36_0294	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC36_0295	COG1660	Displays ATPase and GTPase activities
FORC36_0296	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC36_0297	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC36_0299	COG1137	ATPase activity
FORC36_0300	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FORC36_0302	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FORC36_0303	COG0517	IMP dehydrogenase activity
FORC36_0303	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FORC36_0305	COG1127	ABC transporter
FORC36_0306	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FORC36_0307	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FORC36_0308	COG2854	intermembrane phospholipid transfer
FORC36_0310	COG5007	Belongs to the BolA IbaG family
FORC36_0312	COG0204	Acyl-transferase
FORC36_0313	COG0589	response to stress
FORC36_0317	COG0039	L-malate dehydrogenase activity
FORC36_0318	COG0142	geranyltranstransferase activity
FORC36_0319	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FORC36_0322	COG2966	Psort location CytoplasmicMembrane, score
FORC36_0323	COG3610	response to peptide
FORC36_0335	COG0473	3-isopropylmalate dehydrogenase activity
FORC36_0341	COG1022	Amp-dependent synthetase and ligase
FORC36_0342	COG0028	Belongs to the TPP enzyme family
FORC36_0343	COG0440	acetolactate synthase activity
FORC36_0344	COG3706	GGDEF domain
FORC36_0346	COG0469	pyruvate kinase activity
FORC36_0347	COG1349	DNA-binding transcription factor activity
FORC36_0349	COG3722	fumarate hydratase activity
FORC36_0350	COG0246	Mannitol dehydrogenase
FORC36_0351	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC36_0351	COG2213	PTS system mannitol-specific
FORC36_0352	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FORC36_0355	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORC36_0357	COG1610	YqeY-like protein
FORC36_0358	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FORC36_0360	COG0596	Alpha beta hydrolase
FORC36_0362	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FORC36_0363	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC36_0365	COG0617	tRNA 3'-terminal CCA addition
FORC36_0366	COG3409	Peptidoglycan-binding domain 1 protein
FORC36_0366	COG3267	Type II secretory pathway component ExeA
FORC36_0367	COG4991	sh3 domain protein
FORC36_0368	COG0306	phosphate transporter
FORC36_0369	COG1392	Phosphate transport regulator
FORC36_0370	COG3025	triphosphatase activity
FORC36_0371	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC36_0375	COG1538	Outer membrane efflux protein
FORC36_0376	COG0494	nUDIX hydrolase
FORC36_0377	COG3151	Protein conserved in bacteria
FORC36_0379	COG3150	esterase
FORC36_0380	COG0187	DNA topoisomerase II activity
FORC36_0382	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC36_0383	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC36_0384	COG3105	Protein conserved in bacteria
FORC36_0385	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FORC36_0388	COG0723	plastoquinol--plastocyanin reductase activity
FORC36_0389	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FORC36_0390	COG2857	Cytochrome c1
FORC36_0391	COG0625	glutathione transferase activity
FORC36_0392	COG2969	positive regulation of protein catabolic process
FORC36_0393	COG2823	Periplasmic or secreted lipoprotein
FORC36_0394	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FORC36_0396	COG3107	peptidoglycan biosynthetic process
FORC36_0397	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FORC36_0399	COG3116	cell division
FORC36_0400	COG0768	penicillin binding
FORC36_0402	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FORC36_0403	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORC36_0404	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FORC36_0405	COG0772	Belongs to the SEDS family
FORC36_0407	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC36_0408	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FORC36_0409	COG0849	cell division
FORC36_0410	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FORC36_0413	COG0653	protein targeting
FORC36_0414	COG0494	nUDIX hydrolase
FORC36_0416	COG0505	Belongs to the CarA family
FORC36_0419	COG0730	response to heat
FORC36_0420	COG0583	DNA-binding transcription factor activity
FORC36_0421	COG2860	membrane
FORC36_0422	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC36_0424	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FORC36_0426	COG0493	'glutamate synthase
FORC36_0427	COG0070	glutamate synthase
FORC36_0427	COG0067	glutamate synthase
FORC36_0427	COG0069	glutamate synthase activity
FORC36_0429	COG0069	glutamate synthase activity
FORC36_0429	COG0067	glutamate synthase
FORC36_0429	COG0070	glutamate synthase
FORC36_0430	COG1242	4 iron, 4 sulfur cluster binding
FORC36_0431	COG4251	negative regulation of phosphorylation
FORC36_0431	COG2203	Gaf domain
FORC36_0431	COG5001	Diguanylate cyclase
FORC36_0431	COG3706	GGDEF domain
FORC36_0432	COG2198	Histidine kinase
FORC36_0432	COG0784	Response regulator, receiver
FORC36_0432	COG5002	protein histidine kinase activity
FORC36_0434	COG0745	RESPONSE REGULATOR receiver
FORC36_0440	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FORC36_0446	COG1115	amino acid carrier protein
FORC36_0448	COG0513	Belongs to the DEAD box helicase family
FORC36_0451	COG0716	FMN binding
FORC36_0453	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC36_0454	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FORC36_0455	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FORC36_0459	COG0667	Aldo Keto reductase
FORC36_0464	COG0730	response to heat
FORC36_0468	COG1283	sodium-dependent phosphate transmembrane transporter activity
FORC36_0469	COG0583	DNA-binding transcription factor activity
FORC36_0470	COG0640	Transcriptional regulator
FORC36_0472	COG0728	peptidoglycan biosynthetic process
FORC36_0473	COG0196	riboflavin kinase activity
FORC36_0474	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FORC36_0476	COG1047	Peptidyl-prolyl cis-trans
FORC36_0479	COG3275	phosphorelay sensor kinase activity
FORC36_0480	COG1966	Carbon starvation protein
FORC36_0484	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FORC36_0485	COG1472	Belongs to the glycosyl hydrolase 3 family
FORC36_0486	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC36_0487	COG1605	Chorismate mutase
FORC36_0487	COG0287	Prephenate dehydrogenase
FORC36_0488	COG0739	heme binding
FORC36_0490	COG0488	(ABC) transporter
FORC36_0493	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FORC36_0494	COG1605	Chorismate mutase
FORC36_0494	COG0077	Prephenate dehydratase
FORC36_0495	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC36_0496	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC36_0499	COG0542	response to heat
FORC36_0502	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC36_0504	COG2974	May be involved in recombination
FORC36_0505	COG0745	RESPONSE REGULATOR receiver
FORC36_0506	COG5002	protein histidine kinase activity
FORC36_0508	COG0248	Ppx GppA phosphatase
FORC36_0509	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FORC36_0510	COG0573	inorganic phosphate transmembrane transporter activity
FORC36_0511	COG0581	inorganic phosphate transmembrane transporter activity
FORC36_0513	COG0704	Plays a role in the regulation of phosphate uptake
FORC36_0520	COG0450	alkyl hydroperoxide reductase
FORC36_0521	COG0583	DNA-binding transcription factor activity
FORC36_0522	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FORC36_0524	COG0517	IMP dehydrogenase activity
FORC36_0527	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FORC36_0529	COG1862	Preprotein translocase
FORC36_0530	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC36_0531	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC36_0532	COG0483	inositol monophosphate 1-phosphatase activity
FORC36_0533	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FORC36_0536	COG0822	iron-sulfur transferase activity
FORC36_0539	COG0443	Heat shock 70 kDa protein
FORC36_0540	COG0633	Ferredoxin
FORC36_0541	COG2975	iron-sulfur cluster assembly
FORC36_0544	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FORC36_0549	COG2976	Protein conserved in bacteria
FORC36_0550	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC36_0551	COG1160	GTP binding
FORC36_0553	COG2199	diguanylate cyclase activity
FORC36_0553	COG2203	Gaf domain
FORC36_0556	COG0517	IMP dehydrogenase activity
FORC36_0556	COG0516	GMP reductase activity
FORC36_0557	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FORC36_0557	COG0519	Catalyzes the synthesis of GMP from XMP
FORC36_0559	COG1584	GPR1 FUN34 yaaH family protein
FORC36_0560	COG1115	amino acid carrier protein
FORC36_0562	COG0583	DNA-binding transcription factor activity
FORC36_0567	COG0009	L-threonylcarbamoyladenylate synthase
FORC36_0592	COG0582	viral genome integration into host DNA
FORC36_0594	COG2867	negative regulation of translational initiation
FORC36_0596	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC36_0597	COG0497	DNA recombination
FORC36_0598	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FORC36_0599	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FORC36_0612	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FORC36_0613	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FORC36_0614	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FORC36_0615	COG0583	DNA-binding transcription factor activity
FORC36_0616	COG0590	tRNA wobble adenosine to inosine editing
FORC36_0624	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC36_0625	COG2252	PERMEase
FORC36_0632	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC36_0632	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC36_0637	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FORC36_0638	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FORC36_0639	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FORC36_0640	COG0142	geranyltranstransferase activity
FORC36_0642	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FORC36_0646	COG0583	DNA-binding transcription factor activity
FORC36_0648	COG2363	Small membrane protein
FORC36_0651	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC36_0652	COG1611	Belongs to the LOG family
FORC36_0653	COG3706	GGDEF domain
FORC36_0657	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FORC36_0658	COG1464	Belongs to the NlpA lipoprotein family
FORC36_0659	COG2011	ABC-type metal ion transport system permease component
FORC36_0661	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC36_0663	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC36_0663	COG1263	PTS System
FORC36_0664	COG0366	Alpha amylase catalytic
FORC36_0671	COG1686	Belongs to the peptidase S11 family
FORC36_0672	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FORC36_0673	COG0772	Belongs to the SEDS family
FORC36_0674	COG0768	penicillin binding
FORC36_0676	COG0799	negative regulation of ribosome biogenesis
FORC36_0677	COG1466	dna polymerase III delta subunit
FORC36_0678	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FORC36_0680	COG2888	peptidyl-tyrosine sulfation
FORC36_0682	COG4535	Mg2 and Co2 transporter CorC
FORC36_0683	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FORC36_0684	COG1702	phosphate starvation-inducible protein PhoH
FORC36_0685	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC36_0686	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC36_0693	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FORC36_0695	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC36_0696	COG3094	Invasion gene expression up-regulator, SirB
FORC36_0697	COG2912	Transglutaminase-like superfamily
FORC36_0699	COG3385	transposase activity
FORC36_0702	COG1187	pseudouridine synthase activity
FORC36_0703	COG2840	Smr protein MutS2
FORC36_0704	COG3735	TraB family
FORC36_0707	COG2608	mercury ion transmembrane transporter activity
FORC36_0707	COG2217	Heavy metal translocating P-type atpase
FORC36_0711	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC36_0716	COG3385	transposase activity
FORC36_0720	COG0784	Response regulator, receiver
FORC36_0720	COG0835	chemotaxis
FORC36_0721	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC36_0722	COG1815	bacterial-type flagellum-dependent cell motility
FORC36_0723	COG1558	bacterial-type flagellum-dependent cell motility
FORC36_0724	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FORC36_0725	COG1749	Flagellar hook protein flgE
FORC36_0726	COG4787	bacterial-type flagellum-dependent cell motility
FORC36_0727	COG4786	Flagellar basal body rod
FORC36_0730	COG3951	Flagellar rod assembly protein muramidase FlgJ
FORC36_0730	COG1705	Flagellar rod assembly protein muramidase FlgJ
FORC36_0732	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC36_0734	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC36_0737	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC36_0738	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC36_0739	COG2190	(PTS) system
FORC36_0740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FORC36_0741	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC36_0742	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC36_0743	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FORC36_0744	COG3115	cell septum assembly
FORC36_0749	COG0330	HflC and HflK could
FORC36_0750	COG3118	belongs to the thioredoxin family
FORC36_0751	COG0300	oxidoreductase activity
FORC36_0752	COG1090	epimerase
FORC36_0757	COG0622	Phosphoesterase
FORC36_0761	COG3710	Transcriptional regulator
FORC36_0764	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FORC36_0765	COG0840	transmembrane signaling receptor activity
FORC36_0766	COG3104	oligopeptide transport
FORC36_0768	COG0367	asparagine synthase
FORC36_0769	COG4651	solute:proton antiporter activity
FORC36_0769	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC36_0770	COG1846	Transcriptional regulator
FORC36_0770	COG1940	carbohydrate kinase activity
FORC36_0771	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC36_0772	COG1263	PTS System
FORC36_0772	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC36_0773	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC36_0776	COG0716	FMN binding
FORC36_0778	COG0596	Alpha beta hydrolase
FORC36_0779	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FORC36_0780	COG0033	Phosphoglucomutase
FORC36_0781	COG2964	Protein conserved in bacteria
FORC36_0782	COG0251	oxidation-reduction process
FORC36_0784	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC36_0786	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FORC36_0788	COG2009	succinate dehydrogenase
FORC36_0789	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FORC36_0790	COG1053	succinate dehydrogenase
FORC36_0792	COG0567	Dehydrogenase, E1 component
FORC36_0793	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC36_0796	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC36_0798	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FORC36_0800	COG1918	ferrous iron import across plasma membrane
FORC36_0801	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FORC36_0805	COG3102	Protein conserved in bacteria
FORC36_0806	COG0788	formyltetrahydrofolate deformylase activity
FORC36_0808	COG1199	ATP-dependent helicase activity
FORC36_0809	COG1214	PFAM Peptidase M22, glycoprotease
FORC36_0812	COG0596	Alpha beta hydrolase
FORC36_0813	COG0318	PFAM AMP-dependent synthetase and ligase
FORC36_0814	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FORC36_0816	COG2894	cell division
FORC36_0819	COG2951	lytic endotransglycosylase activity
FORC36_0821	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC36_0823	COG0745	RESPONSE REGULATOR receiver
FORC36_0824	COG5002	protein histidine kinase activity
FORC36_0826	COG1028	Short-chain dehydrogenase reductase Sdr
FORC36_0828	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC36_0833	COG2986	histidine ammonia-lyase
FORC36_0834	COG1216	Glycosyl transferase, family 2
FORC36_0836	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FORC36_0838	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC36_0839	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC36_0847	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FORC36_0848	COG0745	RESPONSE REGULATOR receiver
FORC36_0853	COG3842	ATPase activity
FORC36_0854	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FORC36_0855	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC36_0856	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FORC36_0858	COG2204	response regulator
FORC36_0859	COG4191	Histidine kinase
FORC36_0864	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FORC36_0865	COG0776	regulation of translation
FORC36_0866	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC36_0867	COG1555	photosystem II stabilization
FORC36_0871	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FORC36_0872	COG0436	Aminotransferase
FORC36_0873	COG1169	isochorismate synthase
FORC36_0876	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FORC36_0877	COG1441	menaquinone biosynthetic process
FORC36_0878	COG0318	PFAM AMP-dependent synthetase and ligase
FORC36_0884	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC36_0885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC36_0895	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC36_0896	COG1522	sequence-specific DNA binding
FORC36_0898	COG1946	Acyl-CoA thioesterase
FORC36_0899	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FORC36_0908	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC36_0911	COG3139	Protein of unknown function (DUF1315)
FORC36_0912	COG0252	asparaginase activity
FORC36_0913	COG0616	signal peptide processing
FORC36_0914	COG1902	pentaerythritol trinitrate reductase activity
FORC36_0914	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC36_0915	COG0778	Nitroreductase
FORC36_0916	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC36_0917	COG0123	including yeast histone deacetylase and acetoin utilization protein
FORC36_0919	COG0745	RESPONSE REGULATOR receiver
FORC36_0919	COG3706	GGDEF domain
FORC36_0920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC36_0921	COG2731	YhcH YjgK YiaL family protein
FORC36_0922	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC36_0923	COG0569	domain protein
FORC36_0924	COG3083	sulfuric ester hydrolase activity
FORC36_0926	COG3081	Nucleoid-associated protein
FORC36_0929	COG1757	Na H antiporter
FORC36_0930	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC36_0932	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC36_0933	COG2095	MarC family integral membrane protein
FORC36_0934	COG1454	alcohol dehydrogenase
FORC36_0934	COG1012	belongs to the aldehyde dehydrogenase family
FORC36_0936	COG1028	Short-chain dehydrogenase reductase Sdr
FORC36_0939	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FORC36_0941	COG2056	Na+-H+ antiporter family
FORC36_0942	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC36_0943	COG2885	chlorophyll binding
FORC36_0945	COG0346	lactoylglutathione lyase activity
FORC36_0946	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FORC36_0948	COG4659	FMN binding
FORC36_0950	COG4656	Part of a membrane complex involved in electron transport
FORC36_0957	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FORC36_0959	COG0521	Mo-molybdopterin cofactor biosynthetic process
FORC36_0961	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FORC36_0962	COG0314	molybdopterin synthase activity
FORC36_0965	COG0601	transmembrane transport
FORC36_0966	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC36_0967	COG0444	Belongs to the ABC transporter superfamily
FORC36_0969	COG0435	Glutathione S-transferase
FORC36_0971	COG2350	Protein conserved in bacteria
FORC36_0972	COG1607	acyl-coa hydrolase
FORC36_0975	COG1301	dicarboxylic acid transport
FORC36_0978	COG0135	phosphoribosylanthranilate isomerase activity
FORC36_0978	COG0134	indole-3-glycerol-phosphate synthase activity
FORC36_0979	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FORC36_0980	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC36_0981	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORC36_0982	COG0613	PHP domain protein
FORC36_0983	COG0009	L-threonylcarbamoyladenylate synthase
FORC36_0989	COG5001	Diguanylate cyclase
FORC36_0990	COG0417	DNA replication proofreading
FORC36_0991	COG2197	response regulator
FORC36_1001	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC36_1002	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC36_1009	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FORC36_1010	COG0437	4 iron, 4 sulfur cluster binding
FORC36_1011	COG3301	Polysulphide reductase, NrfD
FORC36_1012	COG1138	Cytochrome C-type biogenesis protein
FORC36_1013	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC36_1014	COG4235	cytochrome complex assembly
FORC36_1014	COG3088	subunit of a heme lyase
FORC36_1017	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC36_1017	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC36_1021	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FORC36_1022	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FORC36_1023	COG0659	secondary active sulfate transmembrane transporter activity
FORC36_1024	COG1530	ribonuclease E activity
FORC36_1027	COG1399	metal-binding, possibly nucleic acid-binding protein
FORC36_1030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC36_1036	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FORC36_1039	COG0084	hydrolase, TatD family'
FORC36_1040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC36_1040	COG1263	PTS System
FORC36_1042	COG0733	neurotransmitter:sodium symporter activity
FORC36_1044	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC36_1045	COG0469	pyruvate kinase activity
FORC36_1046	COG1940	carbohydrate kinase activity
FORC36_1047	COG0784	Response regulator, receiver
FORC36_1047	COG0835	chemotaxis
FORC36_1048	COG0587	DNA-directed DNA polymerase activity
FORC36_1051	COG1028	Short-chain dehydrogenase reductase Sdr
FORC36_1052	COG0616	signal peptide processing
FORC36_1054	COG0539	negative regulation of cytoplasmic translation
FORC36_1056	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FORC36_1057	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FORC36_1058	COG0284	orotidine-5'-phosphate decarboxylase activity
FORC36_1059	COG4174	ABC transporter (Permease)
FORC36_1060	COG4239	(ABC) transporter, permease
FORC36_1061	COG4166	transmembrane transport
FORC36_1062	COG0444	Belongs to the ABC transporter superfamily
FORC36_1063	COG4608	Belongs to the ABC transporter superfamily
FORC36_1068	COG0583	DNA-binding transcription factor activity
FORC36_1070	COG0686	Belongs to the AlaDH PNT family
FORC36_1074	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FORC36_1082	COG0501	Belongs to the peptidase M48B family
FORC36_1084	COG0300	oxidoreductase activity
FORC36_1087	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FORC36_1091	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FORC36_1093	COG0482	sulfurtransferase activity
FORC36_1095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC36_1096	COG2916	Histone family protein nucleoid-structuring protein H-NS
FORC36_1098	COG1757	Na H antiporter
FORC36_1101	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FORC36_1103	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FORC36_1107	COG3012	SEC-C Motif Domain Protein
FORC36_1108	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FORC36_1109	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC36_1110	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC36_1111	COG0215	cysteine-tRNA ligase activity
FORC36_1112	COG1435	thymidine kinase activity
FORC36_1114	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC36_1115	COG0583	DNA-binding transcription factor activity
FORC36_1119	COG2116	formate transmembrane transporter activity
FORC36_1120	COG0390	transport system, permease component
FORC36_1121	COG4459	periplasmic nitrate reductase
FORC36_1122	COG3005	denitrification pathway
FORC36_1129	COG1227	inorganic diphosphatase activity
FORC36_1132	COG4172	Belongs to the ABC transporter superfamily
FORC36_1134	COG4171	peptide transport system, permease
FORC36_1135	COG4168	peptide transport system, permease
FORC36_1137	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FORC36_1138	COG1842	Phage shock protein A
FORC36_1140	COG1983	PspC domain protein
FORC36_1144	COG2818	Glycosylase
FORC36_1145	COG0626	cystathionine gamma-synthase activity
FORC36_1147	COG0733	neurotransmitter:sodium symporter activity
FORC36_1149	COG0564	pseudouridine synthase activity
FORC36_1151	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC36_1152	COG1151	hydroxylamine reductase activity
FORC36_1153	COG3604	Transcriptional regulator
FORC36_1154	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FORC36_1155	COG4136	ATPase activity
FORC36_1156	COG4135	transport system, permease component
FORC36_1157	COG4134	Bacterial extracellular solute-binding protein
FORC36_1159	COG3313	Fe-S protein
FORC36_1166	COG2205	protein histidine kinase activity
FORC36_1169	COG1061	Type III restriction enzyme res subunit
FORC36_1171	COG2814	Major facilitator Superfamily
FORC36_1174	COG0702	epimerase
FORC36_1175	COG1136	(ABC) transporter
FORC36_1182	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FORC36_1183	COG3273	potassium ion transport
FORC36_1183	COG2985	domain, Protein
FORC36_1185	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC36_1186	COG1979	alcohol dehydrogenase
FORC36_1187	COG1737	Transcriptional regulator
FORC36_1188	COG0076	glutamate decarboxylase activity
FORC36_1190	COG2431	L-lysine efflux transmembrane transporter activity
FORC36_1192	COG3070	regulator of competence-specific genes
FORC36_1195	COG5002	protein histidine kinase activity
FORC36_1195	COG5002	protein histidine kinase activity
FORC36_1198	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FORC36_1199	COG4988	ABC transporter
FORC36_1200	COG0492	ferredoxin-NADP+ reductase activity
FORC36_1204	COG0745	RESPONSE REGULATOR receiver
FORC36_1204	COG3706	GGDEF domain
FORC36_1205	COG0471	metal ion transport
FORC36_1206	COG2949	membrane
FORC36_1207	COG0281	malic enzyme
FORC36_1208	COG1643	Atp-dependent helicase
FORC36_1213	COG1346	cytolysis
FORC36_1214	COG1380	Effector of murein hydrolase LrgA
FORC36_1215	COG2925	Exonuclease
FORC36_1232	COG1451	nucleotide metabolic process
FORC36_1235	COG3063	Type IV pilus biogenesis stability protein PilW
FORC36_1238	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC36_1240	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FORC36_1242	COG0625	glutathione transferase activity
FORC36_1247	COG0745	RESPONSE REGULATOR receiver
FORC36_1247	COG3706	GGDEF domain
FORC36_1248	COG1278	Cold shock
FORC36_1251	COG0584	glycerophosphoryl diester phosphodiesterase
FORC36_1252	COG1349	DNA-binding transcription factor activity
FORC36_1254	COG0395	ABC-type sugar transport system, permease component
FORC36_1255	COG1175	transmembrane transport
FORC36_1256	COG1653	transport
FORC36_1259	COG0730	response to heat
FORC36_1261	COG2197	response regulator
FORC36_1270	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC36_1272	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FORC36_1273	COG0372	Belongs to the citrate synthase family
FORC36_1274	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FORC36_1275	COG2828	Protein conserved in bacteria
FORC36_1281	COG0561	phosphatase activity
FORC36_1282	COG0602	queuosine metabolic process
FORC36_1283	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FORC36_1284	COG3706	GGDEF domain
FORC36_1289	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC36_1292	COG2920	part of a sulfur-relay system
FORC36_1294	COG0670	Belongs to the BI1 family
FORC36_1295	COG1126	abc transporter atp-binding protein
FORC36_1296	COG0765	amino acid transport
FORC36_1297	COG4597	amino acid ABC transporter
FORC36_1298	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC36_1300	COG0437	4 iron, 4 sulfur cluster binding
FORC36_1301	COG0348	domain, Protein
FORC36_1302	COG0204	Acyl-transferase
FORC36_1314	COG1846	Transcriptional regulator
FORC36_1318	COG3971	2-oxopent-4-enoate hydratase activity
FORC36_1325	COG3384	dioxygenase
FORC36_1326	COG1012	belongs to the aldehyde dehydrogenase family
FORC36_1328	COG1960	acyl-CoA dehydrogenase activity
FORC36_1329	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FORC36_1332	COG1115	amino acid carrier protein
FORC36_1339	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC36_1342	COG3290	protein histidine kinase activity
FORC36_1343	COG4565	transcriptional regulatory protein
FORC36_1344	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FORC36_1345	COG0363	glucosamine-6-phosphate deaminase activity
FORC36_1346	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FORC36_1353	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC36_1355	COG0438	transferase activity, transferring glycosyl groups
FORC36_1364	COG2204	response regulator
FORC36_1370	COG1366	Belongs to the anti-sigma-factor antagonist family
FORC36_1371	COG1793	dna ligase
FORC36_1372	COG3706	GGDEF domain
FORC36_1374	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC36_1377	COG2996	Protein conserved in bacteria
FORC36_1379	COG3008	intermembrane lipid transfer
FORC36_1380	COG2995	paraquat-inducible protein a
FORC36_1381	COG1132	(ABC) transporter
FORC36_1382	COG1956	GAF domain-containing protein
FORC36_1386	COG0308	aminopeptidase N
FORC36_1388	COG2902	Dehydrogenase
FORC36_1391	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC36_1391	COG0116	Belongs to the methyltransferase superfamily
FORC36_1397	COG1067	ATP-dependent peptidase activity
FORC36_1398	COG3120	sequence-specific DNA binding
FORC36_1405	COG3278	Belongs to the heme-copper respiratory oxidase family
FORC36_1408	COG2010	Cytochrome c
FORC36_1410	COG2217	Heavy metal translocating P-type atpase
FORC36_1413	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC36_1414	COG0589	response to stress
FORC36_1417	COG2992	FlgJ-related protein
FORC36_1420	COG1176	ABC-type spermidine putrescine transport system, permease component I
FORC36_1421	COG1177	transmembrane transport
FORC36_1422	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC36_1423	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC36_1424	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FORC36_1425	COG0004	ammonium transporteR
FORC36_1432	COG0437	4 iron, 4 sulfur cluster binding
FORC36_1433	COG3383	formate dehydrogenase (NAD+) activity
FORC36_1433	COG0243	molybdopterin cofactor binding
FORC36_1439	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC36_1441	COG0488	(ABC) transporter
FORC36_1444	COG3852	Histidine kinase
FORC36_1445	COG2204	response regulator
FORC36_1447	COG4662	Binding-protein-dependent transport system inner membrane component
FORC36_1448	COG3842	ATPase activity
FORC36_1449	COG0746	molybdenum cofactor guanylyltransferase activity
FORC36_1456	COG0840	transmembrane signaling receptor activity
FORC36_1456	COG3290	protein histidine kinase activity
FORC36_1457	COG0791	NLP P60 protein
FORC36_1459	COG3706	GGDEF domain
FORC36_1463	COG0307	riboflavin synthase, alpha
FORC36_1464	COG0534	Mate efflux family protein
FORC36_1473	COG2801	Transposase and inactivated derivatives
FORC36_1483	COG1196	nuclear chromosome segregation
FORC36_1488	COG0582	viral genome integration into host DNA
FORC36_1501	COG0456	acetyltransferase
FORC36_1508	COG2801	Transposase and inactivated derivatives
FORC36_1536	COG2801	Transposase and inactivated derivatives
FORC36_1562	COG0384	phenazine biosynthesis protein PhzF
FORC36_1567	COG0625	glutathione transferase activity
FORC36_1578	COG0346	lactoylglutathione lyase activity
FORC36_1579	COG0346	lactoylglutathione lyase activity
FORC36_1581	COG2801	Transposase and inactivated derivatives
FORC36_1602	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FORC36_1607	COG0582	viral genome integration into host DNA
FORC36_1609	COG0653	protein targeting
FORC36_1630	COG4326	sporulation control protein
FORC36_1632	COG1228	amidohydrolase
FORC36_1633	COG0010	Belongs to the arginase family
FORC36_1635	COG2986	histidine ammonia-lyase
FORC36_1637	COG5640	endopeptidase activity
FORC36_1638	COG2020	methyltransferase activity
FORC36_1639	COG0277	FAD linked oxidase domain protein
FORC36_1639	COG0247	lactate metabolic process
FORC36_1642	COG2885	chlorophyll binding
FORC36_1645	COG0295	cytidine deaminase activity
FORC36_1653	COG0072	phenylalanine-tRNA ligase activity
FORC36_1653	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC36_1655	COG3706	GGDEF domain
FORC36_1655	COG0745	RESPONSE REGULATOR receiver
FORC36_1657	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FORC36_1668	COG0010	Belongs to the arginase family
FORC36_1669	COG0840	transmembrane signaling receptor activity
FORC36_1672	COG2814	Major facilitator Superfamily
FORC36_1675	COG3279	Response regulator of the LytR AlgR family
FORC36_1676	COG5380	lipid catabolic process
FORC36_1677	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FORC36_1682	COG1643	Atp-dependent helicase
FORC36_1684	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FORC36_1692	COG2894	cell division
FORC36_1694	COG4964	Belongs to the GSP D family
FORC36_1700	COG3713	MltA-interacting MipA family protein
FORC36_1704	COG3706	GGDEF domain
FORC36_1706	COG0443	Heat shock 70 kDa protein
FORC36_1707	COG0443	Heat shock 70 kDa protein
FORC36_1716	COG0297	glycogen (starch) synthase activity
FORC36_1716	COG0438	transferase activity, transferring glycosyl groups
FORC36_1717	COG0438	transferase activity, transferring glycosyl groups
FORC36_1722	COG1596	polysaccharide export
FORC36_1725	COG1115	amino acid carrier protein
FORC36_1726	COG1132	(ABC) transporter
FORC36_1727	COG1132	(ABC) transporter
FORC36_1730	COG0783	Belongs to the Dps family
FORC36_1733	COG0814	amino acid
FORC36_1734	COG1597	lipid kinase activity
FORC36_1736	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC36_1737	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC36_1740	COG0583	DNA-binding transcription factor activity
FORC36_1741	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC36_1742	COG1328	CTP reductase activity
FORC36_1743	COG5001	Diguanylate cyclase
FORC36_1743	COG3300	MHYT domain
FORC36_1746	COG2200	EAL domain
FORC36_1746	COG2199	diguanylate cyclase activity
FORC36_1747	COG3706	GGDEF domain
FORC36_1749	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC36_1749	COG4191	Histidine kinase
FORC36_1750	COG0471	metal ion transport
FORC36_1753	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC36_1754	COG3283	Transcriptional regulator of aromatic amino acids metabolism
FORC36_1755	COG3768	UPF0283 membrane protein
FORC36_1756	COG3106	COG3106 Predicted ATPase
FORC36_1759	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORC36_1763	COG0494	nUDIX hydrolase
FORC36_1764	COG0814	amino acid
FORC36_1765	COG1760	l-serine dehydratase
FORC36_1766	COG2200	EAL domain
FORC36_1768	COG0720	synthase
FORC36_1769	COG0840	transmembrane signaling receptor activity
FORC36_1772	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC36_1775	COG2770	Histidine kinase
FORC36_1775	COG3437	response regulator, receiver
FORC36_1776	COG1448	Aminotransferase
FORC36_1780	COG0840	transmembrane signaling receptor activity
FORC36_1781	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC36_1782	COG1846	Transcriptional regulator
FORC36_1787	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FORC36_1790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC36_1791	COG3108	Peptidase M15
FORC36_1792	COG2989	Protein conserved in bacteria
FORC36_1799	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC36_1801	COG0653	protein targeting
FORC36_1803	COG0745	RESPONSE REGULATOR receiver
FORC36_1803	COG3706	GGDEF domain
FORC36_1804	COG0366	Alpha amylase catalytic
FORC36_1806	COG4120	Belongs to the binding-protein-dependent transport system permease family
FORC36_1808	COG3092	negative regulation of chromosome organization
FORC36_1810	COG0857	belongs to the CobB CobQ family
FORC36_1810	COG0280	phosphate acetyltransferase
FORC36_1812	COG0583	DNA-binding transcription factor activity
FORC36_1817	COG1032	radical SAM domain protein
FORC36_1821	COG2207	Transcriptional regulator
FORC36_1826	COG0861	Integral membrane protein TerC family
FORC36_1827	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC36_1828	COG1454	alcohol dehydrogenase
FORC36_1829	COG0235	Class ii aldolase
FORC36_1830	COG4154	Belongs to the RbsD FucU family
FORC36_1831	COG1070	Carbohydrate kinase
FORC36_1832	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
FORC36_1833	COG0738	Major facilitator superfamily
FORC36_1834	COG1349	DNA-binding transcription factor activity
FORC36_1835	COG0840	transmembrane signaling receptor activity
FORC36_1836	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC36_1839	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC36_1857	COG2205	protein histidine kinase activity
FORC36_1857	COG0784	Response regulator, receiver
FORC36_1859	COG0754	glutathionylspermidine amidase activity
FORC36_1861	COG3766	membrane
FORC36_1863	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FORC36_1864	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FORC36_1865	COG2885	chlorophyll binding
FORC36_1866	COG0823	Involved in the tonB-independent uptake of proteins
FORC36_1868	COG0848	biopolymer transport protein
FORC36_1869	COG0811	peptide transport
FORC36_1870	COG0824	Thioesterase
FORC36_1872	COG1294	oxidase, subunit
FORC36_1873	COG1271	oxidase subunit
FORC36_1874	COG2255	four-way junction helicase activity
FORC36_1876	COG0840	transmembrane signaling receptor activity
FORC36_1880	COG4106	trans-aconitate 2-methyltransferase activity
FORC36_1882	COG0189	ligase activity
FORC36_1882	COG4067	protein conserved in archaea
FORC36_1888	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FORC36_1890	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FORC36_1891	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC36_1892	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FORC36_1893	COG0745	RESPONSE REGULATOR receiver
FORC36_1894	COG3381	protein complex oligomerization
FORC36_1896	COG3070	regulator of competence-specific genes
FORC36_1901	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC36_1902	COG3385	transposase activity
FORC36_1903	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC36_1905	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FORC36_1909	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FORC36_1910	COG0542	response to heat
FORC36_1912	COG1278	Cold shock
FORC36_1916	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FORC36_1917	COG1199	ATP-dependent helicase activity
FORC36_1919	COG3923	Primosomal replication protein n
FORC36_1921	COG0840	transmembrane signaling receptor activity
FORC36_1922	COG0708	Exodeoxyribonuclease III
FORC36_1925	COG4215	(ABC) transporter
FORC36_1930	COG1882	Formate acetyltransferase
FORC36_1933	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC36_1936	COG2766	serine protein kinase
FORC36_1937	COG2718	Belongs to the UPF0229 family
FORC36_1938	COG2719	SpoVR family
FORC36_1939	COG2199	diguanylate cyclase activity
FORC36_1940	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FORC36_1942	COG1663	tetraacyldisaccharide 4'-kinase activity
FORC36_1944	COG0658	competence protein
FORC36_1944	COG2333	competence protein COMEC
FORC36_1946	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC36_1948	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC36_1950	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FORC36_1953	COG1252	NADH dehydrogenase
FORC36_1959	COG0537	adenosine 5'-monophosphoramidase activity
FORC36_1964	COG4109	DRTGG domain
FORC36_1965	COG3706	GGDEF domain
FORC36_1966	COG1982	Orn Lys Arg decarboxylase major
FORC36_1967	COG0531	amino acid
FORC36_1968	COG3710	Transcriptional regulator
FORC36_1972	COG2203	Gaf domain
FORC36_1972	COG2199	diguanylate cyclase activity
FORC36_1973	COG2239	Acts as a magnesium transporter
FORC36_1975	COG3550	peptidyl-serine autophosphorylation
FORC36_1976	COG1396	sequence-specific DNA binding
FORC36_1978	COG2814	Major facilitator Superfamily
FORC36_1979	COG0583	DNA-binding transcription factor activity
FORC36_1980	COG1902	pentaerythritol trinitrate reductase activity
FORC36_1981	COG1902	pentaerythritol trinitrate reductase activity
FORC36_1982	COG0604	alcohol dehydrogenase
FORC36_1985	COG2264	protein methyltransferase activity
FORC36_1986	COG1733	regulation of RNA biosynthetic process
FORC36_1988	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FORC36_2004	COG0732	type I restriction modification DNA specificity domain
FORC36_2011	COG2226	methyltransferase
FORC36_2015	COG1785	Belongs to the alkaline phosphatase family
FORC36_2017	COG0346	lactoylglutathione lyase activity
FORC36_2019	COG2983	Belongs to the UPF0260 family
FORC36_2022	COG0745	RESPONSE REGULATOR receiver
FORC36_2023	COG2205	protein histidine kinase activity
FORC36_2031	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FORC36_2035	COG0745	RESPONSE REGULATOR receiver
FORC36_2036	COG0583	DNA-binding transcription factor activity
FORC36_2037	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FORC36_2038	COG1286	toxin biosynthetic process
FORC36_2039	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FORC36_2040	COG0285	dihydrofolate synthase activity
FORC36_2044	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC36_2046	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC36_2047	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FORC36_2047	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC36_2049	COG3101	peptidyl-lysine hydroxylation
FORC36_2050	COG2860	membrane
FORC36_2051	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FORC36_2052	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC36_2054	COG2062	phosphohistidine phosphatase, SixA
FORC36_2056	COG1025	Belongs to the peptidase M16 family
FORC36_2057	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC36_2057	COG1024	Enoyl-CoA hydratase
FORC36_2058	COG0183	Belongs to the thiolase family
FORC36_2061	COG2067	long-chain fatty acid transport protein
FORC36_2062	COG2067	long-chain fatty acid transport protein
FORC36_2063	COG2853	Lipoprotein
FORC36_2065	COG3088	subunit of a heme lyase
FORC36_2065	COG4235	cytochrome complex assembly
FORC36_2066	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC36_2067	COG1138	Cytochrome C-type biogenesis protein
FORC36_2069	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC36_2070	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC36_2071	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC36_2072	COG4133	protoheme IX ABC transporter activity
FORC36_2074	COG0835	chemotaxis
FORC36_2076	COG1192	Involved in chromosome partitioning
FORC36_2077	COG2201	protein-glutamate methylesterase activity
FORC36_2078	COG0643	Histidine kinase
FORC36_2078	COG2198	Histidine kinase
FORC36_2079	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FORC36_2082	COG0455	bacterial-type flagellum organization
FORC36_2086	COG1684	flagellar biosynthetic protein fliR
FORC36_2087	COG1987	bacterial-type flagellum assembly
FORC36_2097	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC36_2099	COG1677	Flagellar hook-basal body complex protein FliE
FORC36_2100	COG2204	response regulator
FORC36_2101	COG4191	Histidine kinase
FORC36_2102	COG2204	response regulator
FORC36_2103	COG1516	flagellar protein fliS
FORC36_2105	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FORC36_2106	COG1334	flagellar protein FlaG
FORC36_2107	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC36_2108	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC36_2109	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC36_2110	COG2837	iron assimilation
FORC36_2116	COG1393	Belongs to the ArsC family
FORC36_2121	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC36_2122	COG2716	regulation of RNA biosynthetic process
FORC36_2123	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FORC36_2126	COG4783	chaperone-mediated protein folding
FORC36_2127	COG1393	Belongs to the ArsC family
FORC36_2131	COG2233	PERMEase
FORC36_2132	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FORC36_2134	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FORC36_2135	COG0121	glutamine amidotransferase
FORC36_2137	COG1960	acyl-CoA dehydrogenase activity
FORC36_2147	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC36_2149	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC36_2151	COG2226	methyltransferase
FORC36_2152	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC36_2153	COG1388	LysM domain
FORC36_2153	COG0741	lytic transglycosylase activity
FORC36_2156	COG0347	Belongs to the P(II) protein family
FORC36_2160	COG0587	DNA-directed DNA polymerase activity
FORC36_2166	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FORC36_2167	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC36_2168	COG0750	zinc metalloprotease
FORC36_2169	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FORC36_2170	COG0575	Belongs to the CDS family
FORC36_2172	COG0233	cytoplasmic translational termination
FORC36_2176	COG0024	Methionine aminopeptidase
FORC36_2177	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FORC36_2180	COG3098	single-species biofilm formation
FORC36_2188	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC36_2192	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FORC36_2194	COG0254	rRNA binding
FORC36_2195	COG1720	tRNA m6t6A37 methyltransferase activity
FORC36_2200	COG0733	neurotransmitter:sodium symporter activity
FORC36_2203	COG0514	ATP-dependent DNA helicase (RecQ)
FORC36_2205	COG3706	GGDEF domain
FORC36_2205	COG0745	RESPONSE REGULATOR receiver
FORC36_2207	COG1477	protein flavinylation
FORC36_2214	COG0271	Belongs to the BolA IbaG family
FORC36_2218	COG2211	Major facilitator Superfamily
FORC36_2220	COG1595	DNA-templated transcription, initiation
FORC36_2222	COG3248	Nucleoside-binding outer membrane protein
FORC36_2223	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FORC36_2224	COG0693	protein deglycase activity
FORC36_2225	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORC36_2226	COG2166	iron-sulfur cluster assembly
FORC36_2227	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FORC36_2228	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FORC36_2232	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC36_2233	COG1074	ATP-dependent DNA helicase activity
FORC36_2234	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FORC36_2235	COG3083	sulfuric ester hydrolase activity
FORC36_2238	COG3141	response to X-ray
FORC36_2239	COG2171	N-acyltransferase activity
FORC36_2240	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FORC36_2242	COG1349	DNA-binding transcription factor activity
FORC36_2243	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC36_2246	COG0569	domain protein
FORC36_2246	COG0189	ligase activity
FORC36_2250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC36_2252	COG0840	transmembrane signaling receptor activity
FORC36_2253	COG2017	converts alpha-aldose to the beta-anomer
FORC36_2254	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FORC36_2256	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC36_2257	COG1609	Transcriptional regulator
FORC36_2259	COG3250	beta-galactosidase activity
FORC36_2260	COG2731	YhcH YjgK YiaL family protein
FORC36_2261	COG0531	amino acid
FORC36_2262	COG0531	amino acid
FORC36_2263	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FORC36_2263	COG3408	Glycogen debranching enzyme
FORC36_2265	COG0583	DNA-binding transcription factor activity
FORC36_2266	COG2059	Chromate
FORC36_2276	COG4964	Belongs to the GSP D family
FORC36_2283	COG1022	Amp-dependent synthetase and ligase
FORC36_2285	COG0583	DNA-binding transcription factor activity
FORC36_2286	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC36_2289	COG5001	Diguanylate cyclase
FORC36_2289	COG5002	protein histidine kinase activity
FORC36_2289	COG3447	MASE1 domain protein
FORC36_2290	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FORC36_2292	COG0560	Phosphoserine phosphatase
FORC36_2297	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FORC36_2298	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC36_2299	COG0084	hydrolase, TatD family'
FORC36_2301	COG3706	GGDEF domain
FORC36_2303	COG0456	acetyltransferase
FORC36_2305	COG3153	acetyltransferase
FORC36_2310	COG0534	Mate efflux family protein
FORC36_2312	COG4785	May be involved in cell division
FORC36_2322	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FORC36_2323	COG0195	Participates in both transcription termination and antitermination
FORC36_2325	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC36_2327	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC36_2328	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FORC36_2329	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FORC36_2331	COG1534	Rna-binding protein
FORC36_2335	COG2027	D-alanyl-D-alanine carboxypeptidase
FORC36_2336	COG2832	Protein of unknown function (DUF454)
FORC36_2338	COG0739	heme binding
FORC36_2341	COG0316	Belongs to the HesB IscA family
FORC36_2343	COG0628	permease
FORC36_2344	COG2813	Specifically methylates the guanine in position
FORC36_2345	COG0784	Response regulator, receiver
FORC36_2345	COG2205	protein histidine kinase activity
FORC36_2347	COG0601	transmembrane transport
FORC36_2348	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC36_2349	COG0444	Belongs to the ABC transporter superfamily
FORC36_2350	COG4608	Belongs to the ABC transporter superfamily
FORC36_2352	COG2971	BadF BadG BcrA BcrD
FORC36_2355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC36_2358	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC36_2359	COG0004	ammonium transporteR
FORC36_2360	COG0347	Belongs to the P(II) protein family
FORC36_2362	COG3835	regulator
FORC36_2363	COG2610	gluconate transmembrane transporter activity
FORC36_2364	COG1929	Belongs to the glycerate kinase type-1 family
FORC36_2365	COG1049	propionate catabolic process, 2-methylcitrate cycle
FORC36_2366	COG1752	Esterase of the alpha-beta hydrolase superfamily
FORC36_2367	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC36_2368	COG1643	Atp-dependent helicase
FORC36_2370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FORC36_2373	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC36_2376	COG0842	Transport permease protein
FORC36_2377	COG1131	(ABC) transporter
FORC36_2378	COG0659	secondary active sulfate transmembrane transporter activity
FORC36_2379	COG0288	reversible hydration of carbon dioxide
FORC36_2382	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC36_2383	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC36_2384	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FORC36_2385	COG2186	Transcriptional regulator
FORC36_2386	COG3023	N-Acetylmuramoyl-L-alanine amidase
FORC36_2388	COG4969	Belongs to the N-Me-Phe pilin family
FORC36_2389	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC36_2390	COG1459	type II secretion system
FORC36_2399	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FORC36_2400	COG4137	Cytochrome C assembly protein
FORC36_2401	COG4536	flavin adenine dinucleotide binding
FORC36_2404	COG2918	glutathione biosynthetic process
FORC36_2405	COG0612	Peptidase, M16
FORC36_2406	COG1238	metal cluster binding
FORC36_2408	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FORC36_2409	COG0511	ligase activity, forming carbon-carbon bonds
FORC36_2409	COG5016	pyruvate
FORC36_2412	COG0527	aspartate kinase activity
FORC36_2413	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC36_2417	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FORC36_2418	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORC36_2419	COG4942	peptidase
FORC36_2419	COG1388	LysM domain
FORC36_2423	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FORC36_2426	COG0148	phosphopyruvate hydratase activity
FORC36_2428	COG3956	TIGRFAM MazG family protein
FORC36_2429	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC36_2431	COG3437	response regulator, receiver
FORC36_2431	COG3850	Histidine kinase
FORC36_2431	COG4999	Histidine kinase
FORC36_2431	COG2205	protein histidine kinase activity
FORC36_2432	COG5001	Diguanylate cyclase
FORC36_2435	COG0736	holo-[acyl-carrier-protein] synthase activity
FORC36_2437	COG1381	Involved in DNA repair and RecF pathway recombination
FORC36_2440	COG0681	Belongs to the peptidase S26 family
FORC36_2442	COG3086	response to oxidative stress
FORC36_2445	COG1595	DNA-templated transcription, initiation
FORC36_2446	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FORC36_2449	COG0354	folic acid binding
FORC36_2452	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC36_2453	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC36_2454	COG3079	Belongs to the UPF0149 family
FORC36_2455	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FORC36_2456	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FORC36_2458	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC36_2461	COG1279	arginine transmembrane transporter activity
FORC36_2462	COG0668	transmembrane transport
FORC36_2463	COG0191	fructose-bisphosphate aldolase activity
FORC36_2467	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FORC36_2471	COG2356	endonuclease I
FORC36_2473	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FORC36_2479	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FORC36_2480	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC36_2481	COG0762	integral membrane protein
FORC36_2485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC36_2491	COG0741	lytic transglycosylase activity
FORC36_2496	COG3437	response regulator, receiver
FORC36_2498	COG1609	Transcriptional regulator
FORC36_2499	COG3394	polysaccharide catabolic process
FORC36_2500	COG1486	melibiose metabolic process
FORC36_2501	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC36_2503	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC36_2504	COG0726	polysaccharide deacetylase
FORC36_2506	COG0795	lipopolysaccharide-transporting ATPase activity
FORC36_2507	COG0795	lipopolysaccharide-transporting ATPase activity
FORC36_2509	COG2927	DNA polymerase III (CHI subunit)
FORC36_2512	COG4269	membrane
FORC36_2514	COG0456	acetyltransferase
FORC36_2522	COG0251	oxidation-reduction process
FORC36_2523	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC36_2526	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FORC36_2527	COG0312	modulator of DNA gyrase
FORC36_2528	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC36_2529	COG3164	Protein of unknown function
FORC36_2530	COG1530	ribonuclease E activity
FORC36_2532	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FORC36_2533	COG1792	Involved in formation and maintenance of cell shape
FORC36_2534	COG1077	Cell shape determining protein MreB Mrl
FORC36_2543	COG1459	type II secretion system
FORC36_2544	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC36_2546	COG3409	Peptidoglycan-binding domain 1 protein
FORC36_2546	COG3267	Type II secretory pathway component ExeA
FORC36_2551	COG2199	diguanylate cyclase activity
FORC36_2551	COG2200	EAL domain
FORC36_2555	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FORC36_2557	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FORC36_2558	COG0527	aspartate kinase activity
FORC36_2559	COG1410	methionine synthase
FORC36_2559	COG0646	methionine synthase
FORC36_2561	COG3706	GGDEF domain
FORC36_2561	COG0745	RESPONSE REGULATOR receiver
FORC36_2564	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC36_2570	COG0735	belongs to the Fur family
FORC36_2573	COG0432	Pfam Uncharacterised protein family UPF0047
FORC36_2575	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC36_2576	COG0305	Participates in initiation and elongation during chromosome replication
FORC36_2582	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FORC36_2583	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FORC36_2592	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FORC36_2598	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FORC36_2600	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FORC36_2602	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FORC36_2603	COG0460	homoserine dehydrogenase
FORC36_2603	COG0527	aspartate kinase activity
FORC36_2604	COG0626	cystathionine gamma-synthase activity
FORC36_2606	COG0281	malic enzyme
FORC36_2608	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FORC36_2609	COG1609	Transcriptional regulator
FORC36_2613	COG1575	Belongs to the MenA family. Type 1 subfamily
FORC36_2616	COG1494	fructose-1,6-bisphosphatase
FORC36_2622	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC36_2624	COG2906	2 iron, 2 sulfur cluster binding
FORC36_2626	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC36_2632	COG2964	Protein conserved in bacteria
FORC36_2633	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC36_2637	COG1047	Peptidyl-prolyl cis-trans
FORC36_2640	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC36_2641	COG0488	(ABC) transporter
FORC36_2643	COG0429	hydrolase of the alpha beta-hydrolase fold
FORC36_2645	COG3954	Phosphoribulokinase
FORC36_2646	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC36_2650	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FORC36_2657	COG0557	exoribonuclease II activity
FORC36_2658	COG0402	S-adenosylhomocysteine deaminase activity
FORC36_2661	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FORC36_2662	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FORC36_2663	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FORC36_2664	COG0330	HflC and HflK could
FORC36_2665	COG0330	HflC and HflK could
FORC36_2666	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FORC36_2669	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FORC36_2670	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC36_2671	COG0802	atpase or kinase
FORC36_2672	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FORC36_2676	COG0471	metal ion transport
FORC36_2680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC36_2683	COG1045	serine acetyltransferase
FORC36_2684	COG4942	peptidase
FORC36_2690	COG1053	succinate dehydrogenase
FORC36_2691	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FORC36_2693	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FORC36_2696	COG1509	lysine 2,3-aminomutase activity
FORC36_2697	COG1285	pathogenesis
FORC36_2701	COG0534	Mate efflux family protein
FORC36_2704	COG3678	ATP-independent chaperone mediated protein folding
FORC36_2705	COG0745	RESPONSE REGULATOR receiver
FORC36_2706	COG2205	protein histidine kinase activity
FORC36_2708	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FORC36_2710	COG1027	Aspartate ammonia-lyase
FORC36_2711	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC36_2714	COG2095	MarC family integral membrane protein
FORC36_2716	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC36_2719	COG0784	Response regulator, receiver
FORC36_2719	COG2198	Histidine kinase
FORC36_2719	COG2205	protein histidine kinase activity
FORC36_2720	COG2814	Major facilitator Superfamily
FORC36_2723	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC36_2725	COG0511	ligase activity, forming carbon-carbon bonds
FORC36_2726	COG0439	Biotin carboxylase
FORC36_2727	COG2264	protein methyltransferase activity
FORC36_2729	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FORC36_2730	COG0840	transmembrane signaling receptor activity
FORC36_2731	COG0789	Transcriptional regulator
FORC36_2733	COG0151	Belongs to the GarS family
FORC36_2736	COG1253	flavin adenine dinucleotide binding
FORC36_2737	COG3068	Protein conserved in bacteria
FORC36_2738	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC36_2739	COG1573	uracil-dna glycosylase
FORC36_2744	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FORC36_2752	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC36_2754	COG4974	Belongs to the 'phage' integrase family
FORC36_2758	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC36_2765	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FORC36_2767	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC36_2769	COG3335	DDE superfamily endonuclease
FORC36_2774	COG4206	TonB-dependent receptor
FORC36_2782	COG2937	Belongs to the GPAT DAPAT family
FORC36_2785	COG1580	Controls the rotational direction of flagella during chemotaxis
FORC36_2786	COG0705	Rhomboid family
FORC36_2789	COG2177	Part of the ABC transporter FtsEX involved in
FORC36_2790	COG2884	Cell division ATP-binding protein ftsE
FORC36_2791	COG0552	protein localization to endoplasmic reticulum
FORC36_2792	COG0742	ribosomal rna small subunit methyltransferase
FORC36_2794	COG2095	MarC family integral membrane protein
FORC36_2802	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC36_2803	COG0640	Transcriptional regulator
FORC36_2804	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FORC36_2805	COG1280	lysine exporter protein (LysE YggA)
FORC36_2806	COG2267	carboxylic ester hydrolase activity
FORC36_2807	COG0561	phosphatase activity
FORC36_2811	COG2200	EAL domain
FORC36_2811	COG2199	diguanylate cyclase activity
FORC36_2811	COG3287	FIST C domain
FORC36_2812	COG1011	Hydrolase
FORC36_2816	COG0019	diaminopimelate decarboxylase activity
FORC36_2819	COG3072	Adenylate cyclase
FORC36_2822	COG2959	enzyme of heme biosynthesis
FORC36_2824	COG2081	HI0933 family
FORC36_2826	COG1528	Iron-storage protein
FORC36_2827	COG0589	response to stress
FORC36_2831	COG5002	protein histidine kinase activity
FORC36_2831	COG5001	Diguanylate cyclase
FORC36_2832	COG1522	sequence-specific DNA binding
FORC36_2834	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FORC36_2835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC36_2836	COG0800	Aldolase
FORC36_2837	COG2610	gluconate transmembrane transporter activity
FORC36_2838	COG3265	gluconokinase activity
FORC36_2839	COG0129	dihydroxy-acid dehydratase activity
FORC36_2840	COG1609	Transcriptional regulator
FORC36_2843	COG0515	serine threonine protein kinase
FORC36_2843	COG2815	serine threonine protein kinase
FORC36_2850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC36_2852	COG4166	transmembrane transport
FORC36_2853	COG4172	Belongs to the ABC transporter superfamily
FORC36_2857	COG1309	transcriptional regulator
FORC36_2858	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC36_2859	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC36_2860	COG2960	long-chain fatty acid transporting porin activity
FORC36_2862	COG0583	DNA-binding transcription factor activity
FORC36_2864	COG3335	DDE superfamily endonuclease
FORC36_2866	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FORC36_2868	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FORC36_2869	COG0408	coproporphyrinogen oxidase activity
FORC36_2873	COG0551	DNA topoisomerase type I activity
FORC36_2875	COG0758	DNA mediated transformation
FORC36_2878	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FORC36_2879	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC36_2879	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC36_2880	COG0569	domain protein
FORC36_2881	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC36_2882	COG1272	protein, Hemolysin III
FORC36_2883	COG4326	sporulation control protein
FORC36_2885	COG3084	Protein conserved in bacteria
FORC36_2887	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FORC36_2888	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC36_2889	COG0204	Acyl-transferase
FORC36_2891	COG0606	chelatase, subunit chli
FORC36_2893	COG3978	acetolactate synthase activity
FORC36_2894	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC36_2895	COG0129	dihydroxy-acid dehydratase activity
FORC36_2897	COG0583	DNA-binding transcription factor activity
FORC36_2898	COG2814	Major facilitator Superfamily
FORC36_2900	COG0765	amino acid transport
FORC36_2910	COG3312	ion transport
FORC36_2911	COG1475	DNA binding
FORC36_2912	COG1192	Involved in chromosome partitioning
FORC36_2914	COG0445	tRNA wobble uridine modification
FORC36_2915	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FORC36_2917	COG0706	membrane insertase activity
FORC36_2920	COG1126	abc transporter atp-binding protein
FORC36_2925	COG4608	Belongs to the ABC transporter superfamily
FORC36_2926	COG0444	Belongs to the ABC transporter superfamily
FORC36_2928	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC36_2928	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FORC36_2932	COG0217	transcriptional regulatory protein
FORC36_2934	COG0583	DNA-binding transcription factor activity
FORC36_2936	COG1136	(ABC) transporter
FORC36_2937	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC36_2940	COG3275	phosphorelay sensor kinase activity
FORC36_2944	COG0786	glutamate:sodium symporter activity
FORC36_2945	COG0786	glutamate:sodium symporter activity
FORC36_2950	COG0189	ligase activity
FORC36_2955	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC36_2956	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC36_2957	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC36_2961	COG1309	transcriptional regulator
FORC36_2966	COG1741	Belongs to the pirin family
FORC36_2968	COG5001	Diguanylate cyclase
FORC36_2969	COG3706	GGDEF domain
FORC36_2980	COG1982	Orn Lys Arg decarboxylase major
FORC36_2981	COG0531	amino acid
FORC36_2982	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FORC36_2983	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FORC36_2984	COG1162	GTPase activity
FORC36_2985	COG2847	Copper chaperone PCu(A)C
FORC36_2986	COG1999	signal sequence binding
FORC36_2991	COG0058	SHG alpha-glucan phosphorylase activity
FORC36_2992	COG1640	4-alpha-glucanotransferase
FORC36_2995	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC36_3003	COG0560	Phosphoserine phosphatase
FORC36_3007	COG1012	belongs to the aldehyde dehydrogenase family
FORC36_3008	COG0625	glutathione transferase activity
FORC36_3010	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC36_3011	COG1283	sodium-dependent phosphate transmembrane transporter activity
FORC36_3012	COG0612	Peptidase, M16
FORC36_3013	COG1609	Transcriptional regulator
FORC36_3018	COG1760	l-serine dehydratase
FORC36_3020	COG0583	DNA-binding transcription factor activity
FORC36_3021	COG0583	DNA-binding transcription factor activity
FORC36_3023	COG0387	Pfam Sodium calcium exchanger
FORC36_3024	COG0586	Pfam SNARE associated Golgi protein
FORC36_3026	COG0642	Histidine kinase
FORC36_3027	COG0745	RESPONSE REGULATOR receiver
FORC36_3032	COG2199	diguanylate cyclase activity
FORC36_3037	COG1609	Transcriptional regulator
FORC36_3040	COG0395	ABC-type sugar transport system, permease component
FORC36_3043	COG1609	Transcriptional regulator
FORC36_3045	COG0747	negative chemotaxis
FORC36_3047	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC36_3048	COG0444	Belongs to the ABC transporter superfamily
FORC36_3049	COG4608	Belongs to the ABC transporter superfamily
FORC36_3051	COG1609	Transcriptional regulator
FORC36_3055	COG4580	involved in the transport of maltose and maltodextrins
FORC36_3057	COG1472	Belongs to the glycosyl hydrolase 3 family
FORC36_3058	COG0534	Mate efflux family protein
FORC36_3060	COG1566	PFAM secretion protein HlyD family protein
FORC36_3067	COG0564	pseudouridine synthase activity
FORC36_3072	COG1609	Transcriptional regulator
FORC36_3074	COG1129	ABC transporter
FORC36_3079	COG2211	Major facilitator Superfamily
FORC36_3081	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC36_3082	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FORC36_3084	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FORC36_3086	COG3708	Transcriptional regulator
FORC36_3086	COG2207	Transcriptional regulator
FORC36_3096	COG1482	cell wall glycoprotein biosynthetic process
FORC36_3097	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC36_3097	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC36_3097	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC36_3098	COG2207	Transcriptional regulator
FORC36_3100	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC36_3101	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC36_3104	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC36_3106	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FORC36_3113	COG3383	formate dehydrogenase (NAD+) activity
FORC36_3115	COG0583	DNA-binding transcription factor activity
FORC36_3116	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FORC36_3124	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FORC36_3128	COG0583	DNA-binding transcription factor activity
FORC36_3129	COG1733	regulation of RNA biosynthetic process
FORC36_3133	COG0137	argininosuccinate synthase activity
FORC36_3135	COG1301	dicarboxylic acid transport
FORC36_3144	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC36_3145	COG2175	clavaminate synthase activity
FORC36_3151	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC36_3153	COG3706	GGDEF domain
FORC36_3156	COG2356	endonuclease I
FORC36_3159	COG1368	sulfuric ester hydrolase activity
FORC36_3160	COG2194	sulfuric ester hydrolase activity
FORC36_3161	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC36_3162	COG2205	protein histidine kinase activity
FORC36_3163	COG0745	RESPONSE REGULATOR receiver
FORC36_3166	COG4221	oxidoreductase activity
FORC36_3171	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC36_3172	COG0076	glutamate decarboxylase activity
FORC36_3175	COG0561	phosphatase activity
FORC36_3178	COG0671	phosphoesterase, PA-phosphatase related
FORC36_3179	COG0351	phosphomethylpyrimidine kinase
FORC36_3188	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC36_3189	COG4771	TonB-dependent receptor
FORC36_3193	COG0393	Putative heavy-metal-binding
FORC36_3196	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC36_3198	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FORC36_3202	COG0753	catalase activity
FORC36_3206	COG0346	lactoylglutathione lyase activity
FORC36_3209	COG2211	Major facilitator Superfamily
FORC36_3212	COG3240	lipase activity
FORC36_3221	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FORC36_3223	COG3040	lipid binding
FORC36_3228	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FORC36_3230	COG2197	response regulator
FORC36_3234	COG0784	Response regulator, receiver
FORC36_3234	COG2205	protein histidine kinase activity
FORC36_3235	COG3111	PFAM Bacterial OB fold (BOF) protein
FORC36_3237	COG2274	protein secretion by the type I secretion system
FORC36_3239	COG1538	Outer membrane efflux protein
FORC36_3243	COG0668	transmembrane transport
FORC36_3248	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC36_3249	COG4946	Tricorn protease homolog
FORC36_3249	COG0793	Belongs to the peptidase S41A family
FORC36_3252	COG1122	ATPase activity
FORC36_3253	COG4720	Psort location CytoplasmicMembrane, score
FORC36_3254	COG1566	PFAM secretion protein HlyD family protein
FORC36_3256	COG3706	GGDEF domain
FORC36_3260	COG3272	Protein of unknown function (DUF1722)
FORC36_3261	COG0789	Transcriptional regulator
FORC36_3262	COG0415	Belongs to the DNA photolyase family
FORC36_3263	COG1388	LysM domain
FORC36_3263	COG1376	ErfK ybiS ycfS ynhG family protein
FORC36_3265	COG0513	Belongs to the DEAD box helicase family
FORC36_3273	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC36_3274	COG0573	inorganic phosphate transmembrane transporter activity
FORC36_3275	COG0581	inorganic phosphate transmembrane transporter activity
FORC36_3277	COG3706	GGDEF domain
FORC36_3277	COG4251	negative regulation of phosphorylation
FORC36_3277	COG5001	Diguanylate cyclase
FORC36_3277	COG2203	Gaf domain
FORC36_3279	COG2304	oxidoreductase activity
FORC36_3283	COG0714	Associated with various cellular activities
FORC36_3297	COG1596	polysaccharide export
FORC36_3299	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC36_3310	COG2354	Protein conserved in bacteria
FORC36_3312	COG0418	dihydroorotase activity
FORC36_3313	COG0633	Ferredoxin
FORC36_3313	COG3217	Mosc domain protein beta barrel domain protein
FORC36_3313	COG0633	Ferredoxin
FORC36_3313	COG3217	Mosc domain protein beta barrel domain protein
FORC36_3324	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC36_3326	COG0848	biopolymer transport protein
FORC36_3327	COG0811	peptide transport
FORC36_3328	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FORC36_3331	COG3721	Heme iron utilization protein
FORC36_3332	COG0748	coenzyme F420 binding
FORC36_3334	COG0835	chemotaxis
FORC36_3334	COG0784	Response regulator, receiver
FORC36_3335	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC36_3336	COG0589	response to stress
FORC36_3338	COG0366	Alpha amylase catalytic
FORC36_3340	COG0840	transmembrane signaling receptor activity
FORC36_3347	COG0739	heme binding
FORC36_3348	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC36_3351	COG2084	Dehydrogenase
FORC36_3355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC36_3359	COG0840	transmembrane signaling receptor activity
FORC36_3362	COG3706	GGDEF domain
FORC36_3363	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC36_3363	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC36_3364	COG1765	OsmC-like protein
FORC36_3365	COG2171	N-acyltransferase activity
FORC36_3369	COG1011	Hydrolase
FORC36_3374	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC36_3375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC36_3375	COG2207	Transcriptional regulator
FORC36_3378	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FORC36_3379	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC36_3380	COG3842	ATPase activity
FORC36_3384	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC36_3385	COG0583	DNA-binding transcription factor activity
FORC36_3388	COG1760	l-serine dehydratase
FORC36_3392	COG1686	Belongs to the peptidase S11 family
FORC36_3397	COG1012	belongs to the aldehyde dehydrogenase family
FORC36_3401	COG4175	Glycine betaine
FORC36_3402	COG3059	membrane
FORC36_3409	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC36_3410	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
FORC36_3411	COG0247	lactate metabolic process
FORC36_3412	COG0546	phosphoglycolate phosphatase activity
FORC36_3414	COG1619	proteins homologs of microcin C7 resistance protein MccF
FORC36_3415	COG2133	pyrroloquinoline quinone binding
FORC36_3417	COG1454	alcohol dehydrogenase
FORC36_3418	COG0443	Heat shock 70 kDa protein
FORC36_3419	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC36_3425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC36_3426	COG3174	membrane
FORC36_3431	COG0814	amino acid
FORC36_3432	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FORC36_3437	COG2962	Rard protein
FORC36_3440	COG0671	phosphoesterase, PA-phosphatase related
FORC36_3442	COG1288	antiporter activity
FORC36_3445	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FORC36_3448	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FORC36_3449	COG2315	Protein conserved in bacteria
FORC36_3455	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC36_3456	COG1879	ABC-type sugar transport system periplasmic component
FORC36_3457	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC36_3458	COG1609	Transcriptional regulator
FORC36_3460	COG0835	chemotaxis
FORC36_3460	COG0784	Response regulator, receiver
FORC36_3462	COG0456	acetyltransferase
FORC36_3465	COG1366	Belongs to the anti-sigma-factor antagonist family
FORC36_3467	COG2172	sigma factor antagonist activity
FORC36_3470	COG3437	response regulator, receiver
FORC36_3471	COG0420	3'-5' exonuclease activity
FORC36_3472	COG0419	ATPase involved in DNA repair
FORC36_3474	COG0583	DNA-binding transcription factor activity
FORC36_3478	COG4964	Belongs to the GSP D family
FORC36_3493	COG0471	metal ion transport
FORC36_3495	COG3290	protein histidine kinase activity
FORC36_3497	COG0110	maltose O-acetyltransferase activity
FORC36_3503	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC36_3504	COG4605	iron ion homeostasis
FORC36_3505	COG4604	ABC transporter, ATP-binding protein
FORC36_3506	COG0789	Transcriptional regulator
FORC36_3512	COG1289	transmembrane transporter activity
FORC36_3513	COG0210	DNA helicase
FORC36_3515	COG1879	ABC-type sugar transport system periplasmic component
FORC36_3520	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FORC36_3521	COG3005	denitrification pathway
FORC36_3526	COG0513	Belongs to the DEAD box helicase family
FORC36_3527	COG0784	Response regulator, receiver
FORC36_3527	COG2205	protein histidine kinase activity
FORC36_3528	COG1716	ATPase activity
FORC36_3528	COG5001	Diguanylate cyclase
FORC36_3533	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC36_3536	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FORC36_3537	COG0513	Belongs to the DEAD box helicase family
FORC36_3539	COG3119	arylsulfatase activity
FORC36_3541	COG3119	arylsulfatase activity
FORC36_3542	COG0641	radical SAM
FORC36_3543	COG0714	Associated with various cellular activities
FORC36_3550	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
FORC36_3552	COG0641	radical SAM
FORC36_3558	COG2814	Major facilitator Superfamily
FORC36_3562	COG0583	DNA-binding transcription factor activity
FORC36_3563	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FORC36_3566	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC36_3569	COG1132	(ABC) transporter
FORC36_3574	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC36_3574	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC36_3585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC36_3585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC36_3585	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FORC36_3586	COG1105	Belongs to the carbohydrate kinase PfkB family
FORC36_3587	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC36_3587	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC36_3588	COG1609	Transcriptional regulator
FORC36_3593	COG0469	pyruvate kinase activity
FORC36_3594	COG2271	Major facilitator Superfamily
FORC36_3595	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC36_3596	COG4191	Histidine kinase
FORC36_3598	COG1979	alcohol dehydrogenase
FORC36_3599	COG2207	Transcriptional regulator
FORC36_3603	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC36_3606	COG3437	response regulator, receiver
FORC36_3606	COG0784	Response regulator, receiver
FORC36_3607	COG0546	phosphoglycolate phosphatase activity
FORC36_3608	COG0840	transmembrane signaling receptor activity
FORC36_3610	COG0513	Belongs to the DEAD box helicase family
FORC36_3613	COG3038	cytochrome b561
FORC36_3615	COG2116	formate transmembrane transporter activity
FORC36_3616	COG0583	DNA-binding transcription factor activity
FORC36_3619	COG3593	DNA synthesis involved in DNA repair
FORC36_3620	COG0737	Belongs to the 5'-nucleotidase family
FORC36_3621	COG0861	Integral membrane protein TerC family
FORC36_3627	COG2267	carboxylic ester hydrolase activity
FORC36_3628	COG2067	long-chain fatty acid transport protein
FORC36_3631	COG2050	protein possibly involved in aromatic compounds catabolism
FORC36_3633	COG4533	DNA binding
FORC36_3635	COG0366	Alpha amylase catalytic
FORC36_3636	COG0583	DNA-binding transcription factor activity
FORC36_3640	COG0484	heat shock protein binding
FORC36_3643	COG1716	ATPase activity
FORC36_3643	COG5001	Diguanylate cyclase
FORC36_3644	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FORC36_3646	COG4181	ATPase activity
FORC36_3647	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FORC36_3648	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC36_3648	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FORC36_3649	COG1984	allophanate hydrolase subunit 2
FORC36_3650	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FORC36_3651	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FORC36_3653	COG3447	MASE1 domain protein
FORC36_3653	COG5002	protein histidine kinase activity
FORC36_3653	COG5001	Diguanylate cyclase
FORC36_3655	COG0583	DNA-binding transcription factor activity
FORC36_3656	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC36_3656	COG1042	CoA-binding domain protein
FORC36_3656	COG0045	succinate-CoA ligase (ADP-forming) activity
FORC36_3660	COG0023	Translation Initiation Factor
FORC36_3683	COG2801	Transposase and inactivated derivatives
FORC36_3684	COG2801	Transposase and inactivated derivatives
FORC36_3685	COG3140	Belongs to the UPF0181 family
FORC36_3688	COG0745	RESPONSE REGULATOR receiver
FORC36_3690	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FORC36_3691	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FORC36_3694	COG3706	GGDEF domain
FORC36_3696	COG0745	RESPONSE REGULATOR receiver
FORC36_3698	COG1846	Transcriptional regulator
FORC36_3699	COG0697	spore germination
FORC36_3701	COG4149	molybdate abc transporter
FORC36_3702	COG0725	ABC transporter, periplasmic molybdate-binding protein
FORC36_3706	COG0189	ligase activity
FORC36_3706	COG4067	protein conserved in archaea
FORC36_3708	COG0840	transmembrane signaling receptor activity
FORC36_3709	COG0602	queuosine metabolic process
FORC36_3710	COG1328	CTP reductase activity
FORC36_3721	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC36_3722	COG3118	belongs to the thioredoxin family
FORC36_3723	COG0477	Major facilitator Superfamily
FORC36_3725	COG0534	Mate efflux family protein
FORC36_3729	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC36_3732	COG0848	biopolymer transport protein
FORC36_3733	COG0811	peptide transport
FORC36_3734	COG0811	peptide transport
FORC36_3740	COG2146	nitrite reductase [NAD(P)H] activity
FORC36_3741	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC36_3747	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC36_3749	COG4251	negative regulation of phosphorylation
FORC36_3749	COG5001	Diguanylate cyclase
FORC36_3749	COG2203	Gaf domain
FORC36_3749	COG3706	GGDEF domain
FORC36_3751	COG0010	Belongs to the arginase family
FORC36_3752	COG0513	Belongs to the DEAD box helicase family
FORC36_3754	COG0523	cobalamin synthesis protein
FORC36_3756	COG2199	diguanylate cyclase activity
FORC36_3759	COG2146	nitrite reductase [NAD(P)H] activity
FORC36_3759	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC36_3760	COG1116	anion transmembrane transporter activity
FORC36_3761	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC36_3762	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC36_3762	COG1116	anion transmembrane transporter activity
FORC36_3763	COG3707	response regulator
FORC36_3766	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC36_3766	COG1648	precorrin-2 dehydrogenase activity
FORC36_3767	COG0243	molybdopterin cofactor binding
FORC36_3768	COG1214	PFAM Peptidase M22, glycoprotease
FORC36_3768	COG0456	acetyltransferase
FORC36_3769	COG0366	Alpha amylase catalytic
FORC36_3770	COG0840	transmembrane signaling receptor activity
FORC36_3771	COG0840	transmembrane signaling receptor activity
FORC36_3774	COG2271	Major facilitator Superfamily
FORC36_3775	COG0584	glycerophosphoryl diester phosphodiesterase
FORC36_3776	COG0312	modulator of DNA gyrase
FORC36_3777	COG0312	modulator of DNA gyrase
FORC36_3779	COG3069	C4-dicarboxylate transmembrane transporter activity
FORC36_3780	COG1704	LemA family
FORC36_3781	COG0501	Belongs to the peptidase M48B family
FORC36_3784	COG3209	COG3209 Rhs family protein
FORC36_3786	COG5444	nuclease activity
FORC36_3787	COG3209	COG3209 Rhs family protein
FORC36_3789	COG3209	COG3209 Rhs family protein
FORC36_3792	COG3501	Rhs element vgr protein
FORC36_3803	COG0631	protein serine/threonine phosphatase activity
FORC36_3810	COG0515	serine threonine protein kinase
FORC36_3810	COG2815	serine threonine protein kinase
FORC36_3814	COG3530	Putative quorum-sensing-regulated virulence factor
FORC36_3819	COG3186	Phenylalanine-4-hydroxylase
FORC36_3820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC36_3826	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FORC36_3828	COG4191	Histidine kinase
FORC36_3828	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC36_3829	COG3437	response regulator, receiver
FORC36_3829	COG0784	Response regulator, receiver
FORC36_3831	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FORC36_3840	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FORC36_3840	COG1073	alpha beta
FORC36_3840	COG3064	Membrane
FORC36_3841	COG2994	toxin metabolic process
FORC36_3849	COG1028	Short-chain dehydrogenase reductase Sdr
FORC36_3851	COG1024	Enoyl-CoA hydratase
FORC36_3852	COG1024	Enoyl-CoA hydratase
FORC36_3853	COG1960	acyl-CoA dehydrogenase activity
FORC36_3855	COG0183	Belongs to the thiolase family
FORC36_3857	COG1960	acyl-CoA dehydrogenase activity
FORC36_3858	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FORC36_3859	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FORC36_3861	COG0450	alkyl hydroperoxide reductase
FORC36_3863	COG1278	Cold shock
FORC36_3866	COG1309	transcriptional regulator
FORC36_3867	COG2130	NADP-dependent
FORC36_3871	COG2197	response regulator
FORC36_3872	COG3851	Histidine kinase
FORC36_3873	COG2271	Major facilitator Superfamily
FORC36_3874	COG1482	cell wall glycoprotein biosynthetic process
FORC36_3875	COG4974	Belongs to the 'phage' integrase family
FORC36_3879	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC36_3890	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC36_3895	COG2199	diguanylate cyclase activity
FORC36_3895	COG2203	Gaf domain
FORC36_3897	COG3036	rescue of stalled ribosome
FORC36_3898	COG1278	Cold shock
FORC36_3904	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC36_3905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC36_3906	COG0840	transmembrane signaling receptor activity
FORC36_3910	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC36_3912	COG4989	oxidoreductase activity
FORC36_3917	COG1914	H( )-stimulated, divalent metal cation uptake system
FORC36_3919	COG0303	'Molybdopterin
FORC36_3920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC36_3921	COG2897	thiosulfate sulfurtransferase activity
FORC36_3925	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FORC36_3926	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FORC36_3929	COG0840	transmembrane signaling receptor activity
FORC36_3931	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC36_3932	COG2885	chlorophyll binding
FORC36_3933	COG0109	protoheme IX farnesyltransferase activity
FORC36_3934	COG1612	heme a metabolic process
FORC36_3939	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FORC36_3940	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FORC36_3941	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FORC36_3942	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC36_3944	COG1280	lysine exporter protein (LysE YggA)
FORC36_3949	COG1846	Transcriptional regulator
FORC36_3950	COG1764	response to oxidative stress
FORC36_3952	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC36_3955	COG0697	spore germination
FORC36_3958	COG2814	Major facilitator Superfamily
FORC36_3959	COG0583	DNA-binding transcription factor activity
FORC36_3960	COG5001	Diguanylate cyclase
FORC36_3960	COG4251	negative regulation of phosphorylation
FORC36_3960	COG3706	GGDEF domain
FORC36_3960	COG2203	Gaf domain
FORC36_3961	COG0251	oxidation-reduction process
FORC36_3964	COG4145	pantothenate transmembrane transporter activity
FORC36_3966	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FORC36_3968	COG1737	Transcriptional regulator
FORC36_3968	COG0837	glucose binding
FORC36_3970	COG1131	(ABC) transporter
FORC36_3971	COG0842	Transport permease protein
FORC36_3976	COG1846	Transcriptional regulator
FORC36_3979	COG0513	Belongs to the DEAD box helicase family
FORC36_3984	COG3568	Endonuclease Exonuclease Phosphatase
FORC36_3988	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC36_4025	COG2356	endonuclease I
FORC36_4030	COG0741	lytic transglycosylase activity
FORC36_4037	COG0330	HflC and HflK could
FORC36_4041	COG3457	Alanine racemase
FORC36_4046	COG2801	Transposase and inactivated derivatives
FORC36_4047	COG3604	Transcriptional regulator
FORC36_4049	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FORC36_4051	COG4208	sulfate ABC transporter
FORC36_4056	COG0628	permease
FORC36_4063	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC36_4065	COG1566	PFAM secretion protein HlyD family protein
FORC36_4072	COG0582	viral genome integration into host DNA
FORC36_4075	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FORC36_4075	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FORC36_4079	COG2197	response regulator
FORC36_4080	COG3850	Histidine kinase
FORC36_4081	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC36_4083	COG0243	molybdopterin cofactor binding
FORC36_4085	COG3005	denitrification pathway
FORC36_4086	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FORC36_4087	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FORC36_4088	COG1737	Transcriptional regulator
FORC36_4089	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC36_4090	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FORC36_4091	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC36_4092	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FORC36_4094	COG1940	carbohydrate kinase activity
FORC36_4095	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC36_4100	COG0183	Belongs to the thiolase family
FORC36_4102	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC36_4103	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC36_4112	COG1879	ABC-type sugar transport system periplasmic component
FORC36_4114	COG2827	Endonuclease containing a URI domain
FORC36_4115	COG3132	Protein of unknown function, DUF480
FORC36_4118	COG0534	Mate efflux family protein
FORC36_4119	COG5002	protein histidine kinase activity
FORC36_4119	COG2205	protein histidine kinase activity
FORC36_4119	COG0784	Response regulator, receiver
FORC36_4124	COG0583	DNA-binding transcription factor activity
FORC36_4129	COG1522	sequence-specific DNA binding
FORC36_4131	COG0531	amino acid
FORC36_4132	COG0121	glutamine amidotransferase
FORC36_4136	COG2205	protein histidine kinase activity
FORC36_4137	COG0745	RESPONSE REGULATOR receiver
FORC36_4142	COG2239	Acts as a magnesium transporter
FORC36_4144	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FORC36_4145	COG0402	S-adenosylhomocysteine deaminase activity
FORC36_4146	COG1067	ATP-dependent peptidase activity
FORC36_4148	COG4172	Belongs to the ABC transporter superfamily
FORC36_4149	COG1505	serine-type exopeptidase activity
FORC36_4150	COG0583	DNA-binding transcription factor activity
FORC36_4151	COG1620	l-lactate permease
FORC36_4153	COG1139	Iron-sulfur cluster binding protein
FORC36_4158	COG2814	Major facilitator Superfamily
FORC36_4164	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC36_4167	COG3015	lipoprotein NlpE involved in copper resistance
FORC36_4168	COG1126	abc transporter atp-binding protein
FORC36_4169	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC36_4170	COG4215	(ABC) transporter
FORC36_4171	COG4160	amino acid transport
FORC36_4174	COG5002	protein histidine kinase activity
FORC36_4174	COG5001	Diguanylate cyclase
FORC36_4175	COG2755	lipolytic protein G-D-S-L family
FORC36_4177	COG0840	transmembrane signaling receptor activity
FORC36_4178	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC36_4184	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC36_4185	COG1028	Short-chain dehydrogenase reductase Sdr
FORC36_4186	COG1169	isochorismate synthase
FORC36_4187	COG1021	2,3-dihydroxybenzoate-AMP ligase
FORC36_4191	COG1021	2,3-dihydroxybenzoate-AMP ligase
FORC36_4193	COG4607	ABC-type enterochelin transport system periplasmic component
FORC36_4194	COG4774	siderophore transport
FORC36_4194	COG1629	transport
FORC36_4198	COG4067	protein conserved in archaea
FORC36_4198	COG0189	ligase activity
FORC36_4203	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC36_4206	COG0488	(ABC) transporter
FORC36_4210	COG1609	Transcriptional regulator
FORC36_4211	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC36_4216	COG1253	flavin adenine dinucleotide binding
FORC36_4218	COG1012	belongs to the aldehyde dehydrogenase family
FORC36_4220	COG3284	Transcriptional regulator
FORC36_4222	COG1879	ABC-type sugar transport system periplasmic component
FORC36_4223	COG0625	glutathione transferase activity
FORC36_4225	COG0384	phenazine biosynthesis protein PhzF
FORC36_4226	COG2197	response regulator
FORC36_4227	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FORC36_4228	COG0673	inositol 2-dehydrogenase activity
FORC36_4233	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FORC36_4235	COG0583	DNA-binding transcription factor activity
FORC36_4237	COG0583	DNA-binding transcription factor activity
FORC36_4238	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FORC36_4242	COG5001	Diguanylate cyclase
FORC36_4242	COG2203	Gaf domain
FORC36_4242	COG3706	GGDEF domain
FORC36_4242	COG4251	negative regulation of phosphorylation
FORC36_4243	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC36_4245	COG1566	PFAM secretion protein HlyD family protein
FORC36_4249	COG2194	sulfuric ester hydrolase activity
FORC36_4253	COG0798	PFAM Bile acid sodium symporter
FORC36_4254	COG0640	Transcriptional regulator
FORC36_4258	COG0583	DNA-binding transcription factor activity
FORC36_4261	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC36_4262	COG0700	Nucleoside recognition
FORC36_4263	COG3366	ferrous iron transmembrane transporter activity
FORC36_4265	COG0366	Alpha amylase catalytic
FORC36_4266	COG0823	Involved in the tonB-independent uptake of proteins
FORC36_4267	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC36_4276	COG0800	Aldolase
FORC36_4277	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC36_4278	COG0697	spore germination
FORC36_4282	COG1917	Cupin 2, conserved barrel domain protein
FORC36_4284	COG1028	Short-chain dehydrogenase reductase Sdr
FORC36_4290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC36_4290	COG3153	acetyltransferase
FORC36_4294	COG0668	transmembrane transport
FORC36_4300	COG0494	nUDIX hydrolase
FORC36_4301	COG1881	PFAM PEBP family protein
FORC36_4302	COG2207	Transcriptional regulator
FORC36_4303	COG3046	protein related to deoxyribodipyrimidine photolyase
FORC36_4309	COG0454	-acetyltransferase
FORC36_4310	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC36_4315	COG1858	cytochrome C peroxidase
FORC36_4319	COG2814	Major facilitator Superfamily
FORC36_4325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC36_4328	COG0583	DNA-binding transcription factor activity
FORC36_4333	COG0513	Belongs to the DEAD box helicase family
FORC36_4340	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC36_4342	COG1357	PFAM Pentapeptide repeats (8 copies)
FORC36_4346	COG3437	response regulator, receiver
FORC36_4348	COG0579	oxidoreductase
FORC36_4354	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FORC36_4357	COG2205	protein histidine kinase activity
FORC36_4361	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FORC36_4364	COG3706	GGDEF domain
FORC36_4368	COG2176	DNA-directed DNA polymerase activity
FORC36_4369	COG0577	efflux transmembrane transporter activity
FORC36_4369	COG1136	(ABC) transporter
FORC36_4370	COG1136	(ABC) transporter
FORC36_4370	COG0577	efflux transmembrane transporter activity
FORC36_4377	COG1120	ATPase activity
FORC36_4378	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC36_4385	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC36_4386	COG3716	PTS system mannose fructose sorbose family IID component
FORC36_4388	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC36_4389	COG2222	sugar isomerase
FORC36_4391	COG1349	DNA-binding transcription factor activity
FORC36_4392	COG1349	DNA-binding transcription factor activity
FORC36_4393	COG2200	EAL domain
FORC36_4394	COG0697	spore germination
FORC36_4395	COG2207	Transcriptional regulator
FORC36_4399	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FORC36_4404	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC36_4405	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC36_4409	COG0840	transmembrane signaling receptor activity
FORC36_4412	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC36_4416	COG0583	DNA-binding transcription factor activity
FORC36_4417	COG1486	melibiose metabolic process
FORC36_4421	COG2258	MOSC domain
FORC36_4422	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC36_4425	COG1917	Cupin 2, conserved barrel domain protein
FORC36_4425	COG2207	Transcriptional regulator
FORC36_4426	COG1335	isochorismatase
FORC36_4427	COG1609	Transcriptional regulator
FORC36_4428	COG3713	MltA-interacting MipA family protein
FORC36_4429	COG0513	Belongs to the DEAD box helicase family
FORC36_4431	COG2186	Transcriptional regulator
FORC36_4433	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC36_4435	COG0246	Mannitol dehydrogenase
FORC36_4436	COG1904	glucuronate isomerase
FORC36_4437	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC36_4438	COG0800	Aldolase
FORC36_4441	COG1028	Short-chain dehydrogenase reductase Sdr
FORC36_4442	COG2999	glutathione oxidoreductase activity
FORC36_4443	COG1902	pentaerythritol trinitrate reductase activity
FORC36_4450	COG0561	phosphatase activity
FORC36_4451	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FORC36_4452	COG3623	hexulose-6-phosphate isomerase
FORC36_4455	COG1132	(ABC) transporter
FORC36_4456	COG5492	domain, Protein
FORC36_4457	COG5426	von Willebrand factor, type A
FORC36_4459	COG1028	Short-chain dehydrogenase reductase Sdr
FORC36_4461	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC36_4462	COG0659	secondary active sulfate transmembrane transporter activity
FORC36_4467	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC36_4468	COG0601	transmembrane transport
FORC36_4470	COG0747	negative chemotaxis
FORC36_4472	COG3119	arylsulfatase activity
FORC36_4473	COG0641	radical SAM
FORC36_4474	COG3119	arylsulfatase activity
FORC36_4475	COG3119	arylsulfatase activity
FORC36_4476	COG5492	domain, Protein
FORC36_4481	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC36_4489	COG2204	response regulator
FORC36_4498	COG0110	maltose O-acetyltransferase activity
FORC36_4501	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC36_4501	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC36_4502	COG1737	Transcriptional regulator
FORC36_4504	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC36_4504	COG1263	PTS System
FORC36_4506	COG2199	diguanylate cyclase activity
FORC36_4506	COG2200	EAL domain
FORC36_4506	COG2203	Gaf domain
FORC36_4507	COG0406	alpha-ribazole phosphatase activity
FORC36_4509	COG0583	DNA-binding transcription factor activity
FORC36_4510	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FORC36_4514	COG2814	Major facilitator Superfamily
FORC36_4517	COG3706	GGDEF domain
FORC36_4517	COG0745	RESPONSE REGULATOR receiver
FORC36_4519	COG0840	transmembrane signaling receptor activity
FORC36_4520	COG2201	protein-glutamate methylesterase activity
FORC36_4521	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FORC36_4522	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC36_4523	COG0840	transmembrane signaling receptor activity
FORC36_4524	COG0835	chemotaxis
FORC36_4527	COG0745	RESPONSE REGULATOR receiver
FORC36_4529	COG1444	tRNA N-acetyltransferase activity
FORC36_4561	COG0194	GDP metabolic process
FORC36_4574	COG0671	phosphoesterase, PA-phosphatase related
FORC36_4613	COG1328	CTP reductase activity
FORC36_4663	COG1129	ABC transporter
FORC36_4697	COG4682	membrane
FORC36_4734	COG0148	phosphopyruvate hydratase activity
FORC36_4749	COG1203	CRISPR-associated helicase, Cas3
FORC36_4779	COG0629	single-stranded DNA binding
FORC36_4786	COG0671	phosphoesterase, PA-phosphatase related
FORC36_4787	COG0671	phosphoesterase, PA-phosphatase related
FORC36_4789	COG1051	belongs to the nudix hydrolase family
FORC36_4799	COG2916	Histone family protein nucleoid-structuring protein H-NS
FORC36_4824	COG0494	nUDIX hydrolase
FORC36_4849	COG3093	addiction module antidote protein HigA
FORC36_4856	COG1199	ATP-dependent helicase activity
FORC36_4870	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FORC36_4884	COG2137	regulation of response to DNA damage stimulus
FORC36_4909	COG3550	peptidyl-serine autophosphorylation
FORC36_4984	COG0678	peroxiredoxin activity
FORC36_4984	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC36_5024	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FORC36_5043	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC36_5046	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC36_5058	COG2925	Exonuclease
FORC36_5067	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC36_5070	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FORC36_5071	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC36_5071	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC36_5079	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FORC36_5081	COG0210	DNA helicase
FORC36_5084	COG2200	EAL domain
FORC36_5088	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FORC36_5089	COG0316	Belongs to the HesB IscA family
FORC36_5092	COG0587	DNA-directed DNA polymerase activity
FORC36_5093	COG0305	Participates in initiation and elongation during chromosome replication
FORC36_5094	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC36_5096	COG0750	zinc metalloprotease
FORC36_5100	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FORC36_5102	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC36_5104	COG0514	ATP-dependent DNA helicase (RecQ)
FORC36_5111	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC36_5125	COG2974	May be involved in recombination
FORC36_5132	COG0497	DNA recombination
FORC36_5137	COG1078	dGTPase activity
FORC36_5139	COG0653	protein targeting
FORC36_5144	COG0740	serine-type endopeptidase activity
FORC36_5152	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FORC36_5169	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FORC36_5175	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC36_5191	COG0210	DNA helicase
FORC36_5257	COG3706	GGDEF domain
FORC36_5260	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FORC36_5266	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FORC36_5269	COG2310	stress, protein
FORC36_5272	COG1358	cellular component organization or biogenesis
FORC36_5279	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC36_5280	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC36_5285	COG3038	cytochrome b561
FORC36_5290	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FORC36_5299	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FORC36_5300	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FORC36_5304	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FORC36_5309	COG1435	thymidine kinase activity
FORC36_5313	COG0822	iron-sulfur transferase activity
FORC36_5315	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FORC36_5320	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC36_5330	COG0776	regulation of translation
FORC36_5339	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FORC36_5352	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FORC36_5355	COG1570	exodeoxyribonuclease VII activity
FORC36_5356	COG2304	oxidoreductase activity
FORC36_5364	COG0776	regulation of translation
FORC36_5365	COG0602	queuosine metabolic process
FORC36_5371	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FORC36_5385	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FORC36_5393	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC36_5393	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC36_5423	COG0105	UTP biosynthetic process
FORC36_5435	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FORC36_5437	COG2194	sulfuric ester hydrolase activity
FORC36_5438	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC36_5444	COG1358	cellular component organization or biogenesis
FORC36_5446	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FORC36_5454	COG2137	regulation of response to DNA damage stimulus
FORC36_5473	COG3341	Caulimovirus viroplasmin
FORC36_5473	COG0328	RNA-DNA hybrid ribonuclease activity
FORC36_5492	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC36_5514	COG0629	single-stranded DNA binding
FORC36_5524	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC36_5532	COG4974	Belongs to the 'phage' integrase family
FORC36_5537	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC36_5541	COG4974	Belongs to the 'phage' integrase family
FORC36_5542	COG0628	permease
FORC36_5546	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FORC36_5556	COG1160	GTP binding
FORC36_5599	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FORC36_5605	COG1192	Involved in chromosome partitioning
FORC36_5606	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC36_5607	COG0776	regulation of translation
FORC36_5617	COG1253	flavin adenine dinucleotide binding
FORC36_5638	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FORC36_5641	COG1475	DNA binding