locus-tag	class	description
FORC53_0002	COG0592	DNA-directed DNA polymerase activity
FORC53_0004	COG0187	DNA topoisomerase II activity
FORC53_0005	COG0071	Belongs to the small heat shock protein (HSP20) family
FORC53_0007	COG3977	Valine--pyruvate aminotransferase
FORC53_0009	COG0751	glycine-tRNA ligase activity
FORC53_0011	COG2119	membrane
FORC53_0016	COG0604	alcohol dehydrogenase
FORC53_0019	COG1739	Uncharacterized protein family UPF0029
FORC53_0020	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC53_0023	COG3335	DDE superfamily endonuclease
FORC53_0024	COG0583	DNA-binding transcription factor activity
FORC53_0026	COG2960	long-chain fatty acid transporting porin activity
FORC53_0027	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC53_0028	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC53_0029	COG1309	transcriptional regulator
FORC53_0033	COG4172	Belongs to the ABC transporter superfamily
FORC53_0034	COG4166	transmembrane transport
FORC53_0036	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC53_0043	COG0515	serine threonine protein kinase
FORC53_0043	COG2815	serine threonine protein kinase
FORC53_0046	COG1609	Transcriptional regulator
FORC53_0047	COG0129	dihydroxy-acid dehydratase activity
FORC53_0048	COG3265	gluconokinase activity
FORC53_0050	COG0800	Aldolase
FORC53_0054	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC53_0055	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FORC53_0057	COG1522	sequence-specific DNA binding
FORC53_0058	COG5001	Diguanylate cyclase
FORC53_0058	COG5002	protein histidine kinase activity
FORC53_0062	COG0589	response to stress
FORC53_0063	COG1528	Iron-storage protein
FORC53_0065	COG2081	HI0933 family
FORC53_0067	COG2959	enzyme of heme biosynthesis
FORC53_0071	COG3072	Adenylate cyclase
FORC53_0074	COG0019	diaminopimelate decarboxylase activity
FORC53_0078	COG1011	Hydrolase
FORC53_0079	COG2199	diguanylate cyclase activity
FORC53_0079	COG2200	EAL domain
FORC53_0079	COG3287	FIST C domain
FORC53_0083	COG0561	phosphatase activity
FORC53_0084	COG2267	carboxylic ester hydrolase activity
FORC53_0085	COG1280	lysine exporter protein (LysE YggA)
FORC53_0086	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FORC53_0087	COG0640	Transcriptional regulator
FORC53_0088	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC53_0097	COG2095	MarC family integral membrane protein
FORC53_0099	COG0742	ribosomal rna small subunit methyltransferase
FORC53_0100	COG0552	protein localization to endoplasmic reticulum
FORC53_0101	COG2884	Cell division ATP-binding protein ftsE
FORC53_0102	COG2177	Part of the ABC transporter FtsEX involved in
FORC53_0105	COG0705	Rhomboid family
FORC53_0106	COG1580	Controls the rotational direction of flagella during chemotaxis
FORC53_0115	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC53_0116	COG4206	TonB-dependent receptor
FORC53_0123	COG3335	DDE superfamily endonuclease
FORC53_0125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC53_0127	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FORC53_0131	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC53_0139	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FORC53_0144	COG1573	uracil-dna glycosylase
FORC53_0145	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC53_0146	COG3068	Protein conserved in bacteria
FORC53_0147	COG1253	flavin adenine dinucleotide binding
FORC53_0150	COG0151	Belongs to the GarS family
FORC53_0152	COG0789	Transcriptional regulator
FORC53_0153	COG0840	transmembrane signaling receptor activity
FORC53_0154	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FORC53_0156	COG2264	protein methyltransferase activity
FORC53_0157	COG0439	Biotin carboxylase
FORC53_0158	COG0511	ligase activity, forming carbon-carbon bonds
FORC53_0160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC53_0163	COG2814	Major facilitator Superfamily
FORC53_0164	COG2205	protein histidine kinase activity
FORC53_0164	COG2198	Histidine kinase
FORC53_0164	COG0784	Response regulator, receiver
FORC53_0168	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC53_0170	COG2095	MarC family integral membrane protein
FORC53_0172	COG4232	protein-disulfide reductase activity
FORC53_0173	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC53_0174	COG1027	Aspartate ammonia-lyase
FORC53_0176	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FORC53_0178	COG2205	protein histidine kinase activity
FORC53_0179	COG0745	RESPONSE REGULATOR receiver
FORC53_0180	COG3678	ATP-independent chaperone mediated protein folding
FORC53_0183	COG0534	Mate efflux family protein
FORC53_0187	COG1285	pathogenesis
FORC53_0188	COG1509	lysine 2,3-aminomutase activity
FORC53_0191	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FORC53_0193	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FORC53_0194	COG1053	succinate dehydrogenase
FORC53_0200	COG4942	peptidase
FORC53_0201	COG1045	serine acetyltransferase
FORC53_0204	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC53_0206	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FORC53_0208	COG0471	metal ion transport
FORC53_0212	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FORC53_0213	COG0802	atpase or kinase
FORC53_0214	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC53_0218	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FORC53_0219	COG0330	HflC and HflK could
FORC53_0220	COG0330	HflC and HflK could
FORC53_0221	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FORC53_0222	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FORC53_0223	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FORC53_0226	COG0402	S-adenosylhomocysteine deaminase activity
FORC53_0227	COG0557	exoribonuclease II activity
FORC53_0234	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FORC53_0238	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC53_0239	COG3954	Phosphoribulokinase
FORC53_0241	COG0429	hydrolase of the alpha beta-hydrolase fold
FORC53_0243	COG0488	(ABC) transporter
FORC53_0244	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC53_0247	COG1047	Peptidyl-prolyl cis-trans
FORC53_0251	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC53_0252	COG2964	Protein conserved in bacteria
FORC53_0254	COG2923	Belongs to the DsrF TusC family
FORC53_0255	COG2168	tRNA wobble position uridine thiolation
FORC53_0258	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC53_0260	COG2906	2 iron, 2 sulfur cluster binding
FORC53_0262	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC53_0268	COG1494	fructose-1,6-bisphosphatase
FORC53_0271	COG1575	Belongs to the MenA family. Type 1 subfamily
FORC53_0275	COG1609	Transcriptional regulator
FORC53_0276	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FORC53_0278	COG0281	malic enzyme
FORC53_0280	COG0626	cystathionine gamma-synthase activity
FORC53_0281	COG0460	homoserine dehydrogenase
FORC53_0281	COG0527	aspartate kinase activity
FORC53_0282	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FORC53_0284	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FORC53_0285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC53_0287	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FORC53_0291	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FORC53_0300	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FORC53_0301	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FORC53_0307	COG0305	Participates in initiation and elongation during chromosome replication
FORC53_0308	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC53_0310	COG0432	Pfam Uncharacterised protein family UPF0047
FORC53_0313	COG0735	belongs to the Fur family
FORC53_0324	COG0745	RESPONSE REGULATOR receiver
FORC53_0324	COG3706	GGDEF domain
FORC53_0325	COG3385	transposase activity
FORC53_0327	COG0646	methionine synthase
FORC53_0327	COG1410	methionine synthase
FORC53_0328	COG0527	aspartate kinase activity
FORC53_0329	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FORC53_0331	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FORC53_0335	COG2200	EAL domain
FORC53_0335	COG2199	diguanylate cyclase activity
FORC53_0340	COG3267	Type II secretory pathway component ExeA
FORC53_0340	COG3409	Peptidoglycan-binding domain 1 protein
FORC53_0342	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC53_0343	COG1459	type II secretion system
FORC53_0352	COG1077	Cell shape determining protein MreB Mrl
FORC53_0353	COG1792	Involved in formation and maintenance of cell shape
FORC53_0354	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FORC53_0356	COG1530	ribonuclease E activity
FORC53_0357	COG3164	Protein of unknown function
FORC53_0358	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC53_0359	COG0312	modulator of DNA gyrase
FORC53_0360	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FORC53_0363	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC53_0364	COG0251	oxidation-reduction process
FORC53_0365	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FORC53_0372	COG0456	acetyltransferase
FORC53_0374	COG4269	membrane
FORC53_0377	COG2927	DNA polymerase III (CHI subunit)
FORC53_0379	COG0795	lipopolysaccharide-transporting ATPase activity
FORC53_0380	COG0795	lipopolysaccharide-transporting ATPase activity
FORC53_0382	COG0726	polysaccharide deacetylase
FORC53_0383	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC53_0385	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC53_0386	COG1486	melibiose metabolic process
FORC53_0388	COG1609	Transcriptional regulator
FORC53_0390	COG3437	response regulator, receiver
FORC53_0395	COG0741	lytic transglycosylase activity
FORC53_0401	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC53_0404	COG1872	DUF167
FORC53_0405	COG0762	integral membrane protein
FORC53_0406	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC53_0407	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FORC53_0413	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FORC53_0414	COG2356	endonuclease I
FORC53_0422	COG0191	fructose-bisphosphate aldolase activity
FORC53_0423	COG0668	transmembrane transport
FORC53_0424	COG1279	arginine transmembrane transporter activity
FORC53_0427	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC53_0429	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FORC53_0430	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FORC53_0431	COG3079	Belongs to the UPF0149 family
FORC53_0432	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC53_0433	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC53_0439	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FORC53_0440	COG1595	DNA-templated transcription, initiation
FORC53_0443	COG3086	response to oxidative stress
FORC53_0445	COG0681	Belongs to the peptidase S26 family
FORC53_0448	COG1381	Involved in DNA repair and RecF pathway recombination
FORC53_0450	COG0736	holo-[acyl-carrier-protein] synthase activity
FORC53_0453	COG5001	Diguanylate cyclase
FORC53_0454	COG4999	Histidine kinase
FORC53_0454	COG2205	protein histidine kinase activity
FORC53_0454	COG3437	response regulator, receiver
FORC53_0454	COG3850	Histidine kinase
FORC53_0456	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC53_0457	COG3956	TIGRFAM MazG family protein
FORC53_0462	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FORC53_0466	COG1388	LysM domain
FORC53_0466	COG4942	peptidase
FORC53_0467	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORC53_0468	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FORC53_0472	COG2963	transposase activity
FORC53_0473	COG2801	Transposase and inactivated derivatives
FORC53_0474	COG3547	Transposase (IS116 IS110 IS902 family)
FORC53_0480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC53_0481	COG2274	protein secretion by the type I secretion system
FORC53_0484	COG2801	Transposase and inactivated derivatives
FORC53_0485	COG2963	transposase activity
FORC53_0489	COG0527	aspartate kinase activity
FORC53_0492	COG5016	pyruvate
FORC53_0492	COG0511	ligase activity, forming carbon-carbon bonds
FORC53_0493	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FORC53_0495	COG1238	metal cluster binding
FORC53_0496	COG0612	Peptidase, M16
FORC53_0500	COG4536	flavin adenine dinucleotide binding
FORC53_0501	COG4137	Cytochrome C assembly protein
FORC53_0502	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FORC53_0510	COG1459	type II secretion system
FORC53_0511	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC53_0514	COG3023	N-Acetylmuramoyl-L-alanine amidase
FORC53_0515	COG2186	Transcriptional regulator
FORC53_0516	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FORC53_0517	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC53_0518	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC53_0521	COG0288	reversible hydration of carbon dioxide
FORC53_0522	COG0659	secondary active sulfate transmembrane transporter activity
FORC53_0523	COG1131	(ABC) transporter
FORC53_0524	COG0842	Transport permease protein
FORC53_0527	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC53_0530	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FORC53_0531	COG1489	DNA binding
FORC53_0532	COG1643	Atp-dependent helicase
FORC53_0533	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC53_0534	COG1752	Esterase of the alpha-beta hydrolase superfamily
FORC53_0535	COG1049	propionate catabolic process, 2-methylcitrate cycle
FORC53_0536	COG1929	Belongs to the glycerate kinase type-1 family
FORC53_0537	COG2610	gluconate transmembrane transporter activity
FORC53_0539	COG3835	regulator
FORC53_0541	COG0347	Belongs to the P(II) protein family
FORC53_0542	COG0004	ammonium transporteR
FORC53_0543	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC53_0546	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC53_0549	COG2971	BadF BadG BcrA BcrD
FORC53_0551	COG4608	Belongs to the ABC transporter superfamily
FORC53_0552	COG0444	Belongs to the ABC transporter superfamily
FORC53_0553	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC53_0554	COG0601	transmembrane transport
FORC53_0556	COG0784	Response regulator, receiver
FORC53_0556	COG2205	protein histidine kinase activity
FORC53_0558	COG0628	permease
FORC53_0563	COG0739	heme binding
FORC53_0565	COG2832	Protein of unknown function (DUF454)
FORC53_0566	COG2027	D-alanyl-D-alanine carboxypeptidase
FORC53_0567	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FORC53_0570	COG1534	Rna-binding protein
FORC53_0572	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FORC53_0573	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FORC53_0574	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC53_0575	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC53_0577	COG0195	Participates in both transcription termination and antitermination
FORC53_0583	COG4785	May be involved in cell division
FORC53_0585	COG0534	Mate efflux family protein
FORC53_0590	COG3153	acetyltransferase
FORC53_0592	COG0456	acetyltransferase
FORC53_0594	COG3706	GGDEF domain
FORC53_0597	COG0084	hydrolase, TatD family'
FORC53_0598	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC53_0599	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FORC53_0604	COG0560	Phosphoserine phosphatase
FORC53_0606	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FORC53_0607	COG3447	MASE1 domain protein
FORC53_0607	COG5001	Diguanylate cyclase
FORC53_0607	COG5002	protein histidine kinase activity
FORC53_0610	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC53_0611	COG0583	DNA-binding transcription factor activity
FORC53_0613	COG1022	Amp-dependent synthetase and ligase
FORC53_0620	COG4964	Belongs to the GSP D family
FORC53_0630	COG2059	Chromate
FORC53_0631	COG0583	DNA-binding transcription factor activity
FORC53_0633	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FORC53_0633	COG3408	Glycogen debranching enzyme
FORC53_0634	COG0531	amino acid
FORC53_0635	COG0531	amino acid
FORC53_0636	COG2731	YhcH YjgK YiaL family protein
FORC53_0637	COG3250	beta-galactosidase activity
FORC53_0639	COG1609	Transcriptional regulator
FORC53_0640	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC53_0643	COG2017	converts alpha-aldose to the beta-anomer
FORC53_0644	COG0840	transmembrane signaling receptor activity
FORC53_0646	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC53_0649	COG0569	domain protein
FORC53_0649	COG0189	ligase activity
FORC53_0652	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC53_0653	COG1349	DNA-binding transcription factor activity
FORC53_0655	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FORC53_0656	COG2171	N-acyltransferase activity
FORC53_0657	COG3141	response to X-ray
FORC53_0660	COG3083	sulfuric ester hydrolase activity
FORC53_0661	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FORC53_0662	COG1074	ATP-dependent DNA helicase activity
FORC53_0663	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC53_0667	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FORC53_0668	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FORC53_0669	COG2166	iron-sulfur cluster assembly
FORC53_0673	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORC53_0674	COG0693	protein deglycase activity
FORC53_0675	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FORC53_0676	COG3248	Nucleoside-binding outer membrane protein
FORC53_0678	COG1595	DNA-templated transcription, initiation
FORC53_0680	COG2211	Major facilitator Superfamily
FORC53_0684	COG0271	Belongs to the BolA IbaG family
FORC53_0691	COG1477	protein flavinylation
FORC53_0693	COG3706	GGDEF domain
FORC53_0693	COG0745	RESPONSE REGULATOR receiver
FORC53_0695	COG0514	ATP-dependent DNA helicase (RecQ)
FORC53_0698	COG0733	neurotransmitter:sodium symporter activity
FORC53_0704	COG1720	tRNA m6t6A37 methyltransferase activity
FORC53_0705	COG0254	rRNA binding
FORC53_0706	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FORC53_0710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC53_0718	COG3098	single-species biofilm formation
FORC53_0721	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FORC53_0722	COG0024	Methionine aminopeptidase
FORC53_0726	COG0233	cytoplasmic translational termination
FORC53_0728	COG0575	Belongs to the CDS family
FORC53_0729	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FORC53_0730	COG0750	zinc metalloprotease
FORC53_0731	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC53_0732	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FORC53_0733	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC53_0738	COG0587	DNA-directed DNA polymerase activity
FORC53_0742	COG0347	Belongs to the P(II) protein family
FORC53_0743	COG3021	interspecies interaction between organisms
FORC53_0745	COG0741	lytic transglycosylase activity
FORC53_0745	COG1388	LysM domain
FORC53_0746	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC53_0747	COG2226	methyltransferase
FORC53_0749	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC53_0751	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC53_0754	COG1960	acyl-CoA dehydrogenase activity
FORC53_0756	COG0121	glutamine amidotransferase
FORC53_0757	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FORC53_0759	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FORC53_0760	COG2233	PERMEase
FORC53_0764	COG1393	Belongs to the ArsC family
FORC53_0765	COG4783	chaperone-mediated protein folding
FORC53_0768	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FORC53_0769	COG2716	regulation of RNA biosynthetic process
FORC53_0770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC53_0775	COG1393	Belongs to the ArsC family
FORC53_0781	COG2837	iron assimilation
FORC53_0782	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC53_0783	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC53_0784	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC53_0785	COG1334	flagellar protein FlaG
FORC53_0786	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FORC53_0788	COG1516	flagellar protein fliS
FORC53_0789	COG2204	response regulator
FORC53_0790	COG4191	Histidine kinase
FORC53_0791	COG2204	response regulator
FORC53_0792	COG1677	Flagellar hook-basal body complex protein FliE
FORC53_0794	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC53_0799	COG1580	Controls the rotational direction of flagella during chemotaxis
FORC53_0804	COG1987	bacterial-type flagellum assembly
FORC53_0805	COG1684	flagellar biosynthetic protein fliR
FORC53_0809	COG0455	bacterial-type flagellum organization
FORC53_0812	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FORC53_0813	COG2198	Histidine kinase
FORC53_0813	COG0643	Histidine kinase
FORC53_0815	COG1192	Involved in chromosome partitioning
FORC53_0817	COG0835	chemotaxis
FORC53_0819	COG4133	protoheme IX ABC transporter activity
FORC53_0820	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC53_0821	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC53_0822	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC53_0824	COG1138	Cytochrome C-type biogenesis protein
FORC53_0825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC53_0826	COG3088	subunit of a heme lyase
FORC53_0826	COG4235	cytochrome complex assembly
FORC53_0828	COG2853	Lipoprotein
FORC53_0829	COG2067	long-chain fatty acid transport protein
FORC53_0830	COG2067	long-chain fatty acid transport protein
FORC53_0833	COG0183	Belongs to the thiolase family
FORC53_0835	COG1025	Belongs to the peptidase M16 family
FORC53_0837	COG2062	phosphohistidine phosphatase, SixA
FORC53_0838	COG2840	Smr protein MutS2
FORC53_0839	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC53_0841	COG2860	membrane
FORC53_0842	COG3101	peptidyl-lysine hydroxylation
FORC53_0844	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FORC53_0844	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC53_0845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC53_0847	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC53_0851	COG0285	dihydrofolate synthase activity
FORC53_0852	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FORC53_0853	COG1286	toxin biosynthetic process
FORC53_0854	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FORC53_0855	COG0583	DNA-binding transcription factor activity
FORC53_0856	COG0745	RESPONSE REGULATOR receiver
FORC53_0860	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FORC53_0864	COG2205	protein histidine kinase activity
FORC53_0865	COG0745	RESPONSE REGULATOR receiver
FORC53_0868	COG2983	Belongs to the UPF0260 family
FORC53_0870	COG0346	lactoylglutathione lyase activity
FORC53_0872	COG1785	Belongs to the alkaline phosphatase family
FORC53_0876	COG2226	methyltransferase
FORC53_0883	COG0732	type I restriction modification DNA specificity domain
FORC53_0901	COG1396	sequence-specific DNA binding
FORC53_0902	COG3550	peptidyl-serine autophosphorylation
FORC53_0904	COG2239	Acts as a magnesium transporter
FORC53_0905	COG2203	Gaf domain
FORC53_0905	COG2199	diguanylate cyclase activity
FORC53_0909	COG3710	Transcriptional regulator
FORC53_0910	COG0531	amino acid
FORC53_0911	COG1982	Orn Lys Arg decarboxylase major
FORC53_0912	COG3706	GGDEF domain
FORC53_0913	COG4109	DRTGG domain
FORC53_0918	COG0537	adenosine 5'-monophosphoramidase activity
FORC53_0924	COG1252	NADH dehydrogenase
FORC53_0927	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FORC53_0929	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC53_0931	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC53_0933	COG0658	competence protein
FORC53_0933	COG2333	competence protein COMEC
FORC53_0934	COG1132	(ABC) transporter
FORC53_0935	COG1663	tetraacyldisaccharide 4'-kinase activity
FORC53_0937	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FORC53_0938	COG2199	diguanylate cyclase activity
FORC53_0939	COG2719	SpoVR family
FORC53_0940	COG2718	Belongs to the UPF0229 family
FORC53_0941	COG2766	serine protein kinase
FORC53_0944	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC53_0947	COG1882	Formate acetyltransferase
FORC53_0952	COG4215	(ABC) transporter
FORC53_0955	COG0708	Exodeoxyribonuclease III
FORC53_0956	COG0840	transmembrane signaling receptor activity
FORC53_0958	COG3923	Primosomal replication protein n
FORC53_0960	COG1199	ATP-dependent helicase activity
FORC53_0961	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FORC53_0965	COG1278	Cold shock
FORC53_0967	COG0542	response to heat
FORC53_0968	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FORC53_0969	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FORC53_0972	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FORC53_0974	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC53_0975	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC53_0976	COG0297	glycogen (starch) synthase activity
FORC53_0980	COG3070	regulator of competence-specific genes
FORC53_0982	COG3381	protein complex oligomerization
FORC53_0983	COG0745	RESPONSE REGULATOR receiver
FORC53_0984	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FORC53_0985	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC53_0986	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FORC53_0988	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FORC53_0994	COG4067	protein conserved in archaea
FORC53_0994	COG0189	ligase activity
FORC53_0996	COG4106	trans-aconitate 2-methyltransferase activity
FORC53_0998	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FORC53_1000	COG0840	transmembrane signaling receptor activity
FORC53_1002	COG2255	four-way junction helicase activity
FORC53_1003	COG1271	oxidase subunit
FORC53_1004	COG1294	oxidase, subunit
FORC53_1006	COG0824	Thioesterase
FORC53_1007	COG0811	peptide transport
FORC53_1010	COG0823	Involved in the tonB-independent uptake of proteins
FORC53_1011	COG2885	chlorophyll binding
FORC53_1012	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FORC53_1013	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FORC53_1015	COG3766	membrane
FORC53_1017	COG0754	glutathionylspermidine amidase activity
FORC53_1019	COG2205	protein histidine kinase activity
FORC53_1019	COG0784	Response regulator, receiver
FORC53_1039	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC53_1042	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC53_1044	COG1349	DNA-binding transcription factor activity
FORC53_1045	COG0738	Major facilitator superfamily
FORC53_1046	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
FORC53_1047	COG1070	Carbohydrate kinase
FORC53_1048	COG4154	Belongs to the RbsD FucU family
FORC53_1049	COG0235	Class ii aldolase
FORC53_1050	COG1454	alcohol dehydrogenase
FORC53_1051	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC53_1052	COG0861	Integral membrane protein TerC family
FORC53_1057	COG2207	Transcriptional regulator
FORC53_1061	COG1032	radical SAM domain protein
FORC53_1066	COG0583	DNA-binding transcription factor activity
FORC53_1068	COG0280	phosphate acetyltransferase
FORC53_1068	COG0857	belongs to the CobB CobQ family
FORC53_1070	COG3092	negative regulation of chromosome organization
FORC53_1072	COG4120	Belongs to the binding-protein-dependent transport system permease family
FORC53_1074	COG0366	Alpha amylase catalytic
FORC53_1075	COG3706	GGDEF domain
FORC53_1075	COG0745	RESPONSE REGULATOR receiver
FORC53_1077	COG0653	protein targeting
FORC53_1079	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC53_1080	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC53_1085	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FORC53_1090	COG1846	Transcriptional regulator
FORC53_1091	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC53_1096	COG1448	Aminotransferase
FORC53_1097	COG2770	Histidine kinase
FORC53_1097	COG3437	response regulator, receiver
FORC53_1100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC53_1103	COG0840	transmembrane signaling receptor activity
FORC53_1104	COG0720	synthase
FORC53_1106	COG2200	EAL domain
FORC53_1107	COG1760	l-serine dehydratase
FORC53_1108	COG0814	amino acid
FORC53_1109	COG0494	nUDIX hydrolase
FORC53_1113	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORC53_1116	COG3106	COG3106 Predicted ATPase
FORC53_1117	COG3768	UPF0283 membrane protein
FORC53_1118	COG3283	Transcriptional regulator of aromatic amino acids metabolism
FORC53_1119	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC53_1122	COG0471	metal ion transport
FORC53_1123	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC53_1123	COG4191	Histidine kinase
FORC53_1125	COG3706	GGDEF domain
FORC53_1129	COG3300	MHYT domain
FORC53_1129	COG5001	Diguanylate cyclase
FORC53_1130	COG1328	CTP reductase activity
FORC53_1131	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC53_1132	COG0583	DNA-binding transcription factor activity
FORC53_1135	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC53_1136	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC53_1138	COG1597	lipid kinase activity
FORC53_1139	COG0814	amino acid
FORC53_1142	COG0783	Belongs to the Dps family
FORC53_1145	COG1132	(ABC) transporter
FORC53_1146	COG1132	(ABC) transporter
FORC53_1147	COG1115	amino acid carrier protein
FORC53_1150	COG1596	polysaccharide export
FORC53_1155	COG0438	transferase activity, transferring glycosyl groups
FORC53_1156	COG0297	glycogen (starch) synthase activity
FORC53_1156	COG0438	transferase activity, transferring glycosyl groups
FORC53_1165	COG0443	Heat shock 70 kDa protein
FORC53_1169	COG3706	GGDEF domain
FORC53_1173	COG3713	MltA-interacting MipA family protein
FORC53_1179	COG4964	Belongs to the GSP D family
FORC53_1181	COG2894	cell division
FORC53_1189	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FORC53_1191	COG1643	Atp-dependent helicase
FORC53_1196	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FORC53_1198	COG2814	Major facilitator Superfamily
FORC53_1201	COG0840	transmembrane signaling receptor activity
FORC53_1202	COG0010	Belongs to the arginase family
FORC53_1215	COG3706	GGDEF domain
FORC53_1215	COG0745	RESPONSE REGULATOR receiver
FORC53_1225	COG0295	cytidine deaminase activity
FORC53_1228	COG2885	chlorophyll binding
FORC53_1231	COG0277	FAD linked oxidase domain protein
FORC53_1231	COG0247	lactate metabolic process
FORC53_1232	COG2020	methyltransferase activity
FORC53_1233	COG5640	endopeptidase activity
FORC53_1238	COG0010	Belongs to the arginase family
FORC53_1239	COG1228	amidohydrolase
FORC53_1241	COG4326	sporulation control protein
FORC53_1263	COG2944	sequence-specific DNA binding
FORC53_1277	COG3738	Protein conserved in bacteria
FORC53_1295	COG3738	Protein conserved in bacteria
FORC53_1298	COG1942	4-Oxalocrotonate Tautomerase
FORC53_1308	COG1280	lysine exporter protein (LysE YggA)
FORC53_1320	COG0251	oxidation-reduction process
FORC53_1343	COG4628	conserved protein (DUF2132)
FORC53_1346	COG0384	phenazine biosynthesis protein PhzF
FORC53_1351	COG4628	conserved protein (DUF2132)
FORC53_1383	COG0625	glutathione transferase activity
FORC53_1395	COG0456	acetyltransferase
FORC53_1396	COG0384	phenazine biosynthesis protein PhzF
FORC53_1399	COG0251	oxidation-reduction process
FORC53_1424	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC53_1431	COG4628	conserved protein (DUF2132)
FORC53_1436	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC53_1442	COG2801	Transposase and inactivated derivatives
FORC53_1448	COG0534	Mate efflux family protein
FORC53_1449	COG0307	riboflavin synthase, alpha
FORC53_1453	COG3706	GGDEF domain
FORC53_1455	COG0791	NLP P60 protein
FORC53_1456	COG0840	transmembrane signaling receptor activity
FORC53_1462	COG0746	molybdenum cofactor guanylyltransferase activity
FORC53_1463	COG3842	ATPase activity
FORC53_1464	COG4662	Binding-protein-dependent transport system inner membrane component
FORC53_1466	COG2204	response regulator
FORC53_1467	COG3852	Histidine kinase
FORC53_1470	COG0488	(ABC) transporter
FORC53_1471	COG0840	transmembrane signaling receptor activity
FORC53_1472	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC53_1478	COG3383	formate dehydrogenase (NAD+) activity
FORC53_1478	COG0243	molybdopterin cofactor binding
FORC53_1479	COG0437	4 iron, 4 sulfur cluster binding
FORC53_1488	COG0004	ammonium transporteR
FORC53_1489	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FORC53_1490	COG3385	transposase activity
FORC53_1491	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC53_1492	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC53_1493	COG1177	transmembrane transport
FORC53_1494	COG1176	ABC-type spermidine putrescine transport system, permease component I
FORC53_1497	COG2992	FlgJ-related protein
FORC53_1499	COG0037	tRNA processing
FORC53_1500	COG0589	response to stress
FORC53_1501	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC53_1504	COG2217	Heavy metal translocating P-type atpase
FORC53_1506	COG2010	Cytochrome c
FORC53_1509	COG3278	Belongs to the heme-copper respiratory oxidase family
FORC53_1524	COG4128	Pfam Zonular occludens toxin
FORC53_1530	COG3120	sequence-specific DNA binding
FORC53_1531	COG1067	ATP-dependent peptidase activity
FORC53_1535	COG0488	(ABC) transporter
FORC53_1537	COG0116	Belongs to the methyltransferase superfamily
FORC53_1537	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC53_1540	COG2902	Dehydrogenase
FORC53_1541	COG0308	aminopeptidase N
FORC53_1546	COG1956	GAF domain-containing protein
FORC53_1547	COG1132	(ABC) transporter
FORC53_1548	COG2995	paraquat-inducible protein a
FORC53_1549	COG3008	intermembrane lipid transfer
FORC53_1551	COG2996	Protein conserved in bacteria
FORC53_1554	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC53_1556	COG3706	GGDEF domain
FORC53_1557	COG1793	dna ligase
FORC53_1558	COG1366	Belongs to the anti-sigma-factor antagonist family
FORC53_1564	COG2204	response regulator
FORC53_1573	COG0438	transferase activity, transferring glycosyl groups
FORC53_1575	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC53_1583	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FORC53_1584	COG0363	glucosamine-6-phosphate deaminase activity
FORC53_1585	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FORC53_1586	COG4565	transcriptional regulatory protein
FORC53_1587	COG3290	protein histidine kinase activity
FORC53_1590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC53_1596	COG1115	amino acid carrier protein
FORC53_1599	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FORC53_1600	COG0204	Acyl-transferase
FORC53_1601	COG0348	domain, Protein
FORC53_1602	COG0437	4 iron, 4 sulfur cluster binding
FORC53_1604	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC53_1605	COG4597	amino acid ABC transporter
FORC53_1606	COG0765	amino acid transport
FORC53_1607	COG1126	abc transporter atp-binding protein
FORC53_1608	COG0670	Belongs to the BI1 family
FORC53_1610	COG2920	part of a sulfur-relay system
FORC53_1613	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC53_1644	COG3706	GGDEF domain
FORC53_1645	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FORC53_1646	COG0602	queuosine metabolic process
FORC53_1647	COG0561	phosphatase activity
FORC53_1657	COG2828	Protein conserved in bacteria
FORC53_1659	COG0372	Belongs to the citrate synthase family
FORC53_1660	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FORC53_1662	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC53_1670	COG2197	response regulator
FORC53_1672	COG0730	response to heat
FORC53_1675	COG1653	transport
FORC53_1676	COG1175	transmembrane transport
FORC53_1677	COG0395	ABC-type sugar transport system, permease component
FORC53_1678	COG3842	ATPase activity
FORC53_1679	COG1349	DNA-binding transcription factor activity
FORC53_1680	COG0584	glycerophosphoryl diester phosphodiesterase
FORC53_1683	COG1278	Cold shock
FORC53_1684	COG3706	GGDEF domain
FORC53_1684	COG0745	RESPONSE REGULATOR receiver
FORC53_1689	COG0625	glutathione transferase activity
FORC53_1691	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FORC53_1693	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC53_1696	COG3063	Type IV pilus biogenesis stability protein PilW
FORC53_1699	COG1451	nucleotide metabolic process
FORC53_1706	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FORC53_1708	COG2988	succinylglutamate desuccinylase activity
FORC53_1716	COG2925	Exonuclease
FORC53_1717	COG1380	Effector of murein hydrolase LrgA
FORC53_1718	COG1346	cytolysis
FORC53_1723	COG1643	Atp-dependent helicase
FORC53_1724	COG0281	malic enzyme
FORC53_1725	COG2949	membrane
FORC53_1726	COG0471	metal ion transport
FORC53_1727	COG3706	GGDEF domain
FORC53_1727	COG0745	RESPONSE REGULATOR receiver
FORC53_1731	COG0492	ferredoxin-NADP+ reductase activity
FORC53_1732	COG4988	ABC transporter
FORC53_1733	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FORC53_1736	COG5002	protein histidine kinase activity
FORC53_1736	COG5002	protein histidine kinase activity
FORC53_1739	COG3070	regulator of competence-specific genes
FORC53_1741	COG2431	L-lysine efflux transmembrane transporter activity
FORC53_1743	COG0076	glutamate decarboxylase activity
FORC53_1744	COG1737	Transcriptional regulator
FORC53_1745	COG1979	alcohol dehydrogenase
FORC53_1746	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC53_1747	COG3273	potassium ion transport
FORC53_1747	COG2985	domain, Protein
FORC53_1748	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FORC53_1754	COG1136	(ABC) transporter
FORC53_1755	COG0702	epimerase
FORC53_1758	COG2814	Major facilitator Superfamily
FORC53_1760	COG1061	Type III restriction enzyme res subunit
FORC53_1763	COG2205	protein histidine kinase activity
FORC53_1770	COG3313	Fe-S protein
FORC53_1772	COG4134	Bacterial extracellular solute-binding protein
FORC53_1773	COG4135	transport system, permease component
FORC53_1774	COG4136	ATPase activity
FORC53_1775	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FORC53_1776	COG3604	Transcriptional regulator
FORC53_1777	COG1151	hydroxylamine reductase activity
FORC53_1778	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC53_1780	COG0564	pseudouridine synthase activity
FORC53_1782	COG0733	neurotransmitter:sodium symporter activity
FORC53_1784	COG0626	cystathionine gamma-synthase activity
FORC53_1785	COG2818	Glycosylase
FORC53_1789	COG1983	PspC domain protein
FORC53_1791	COG1842	Phage shock protein A
FORC53_1792	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FORC53_1794	COG4168	peptide transport system, permease
FORC53_1795	COG4171	peptide transport system, permease
FORC53_1797	COG4172	Belongs to the ABC transporter superfamily
FORC53_1800	COG1227	inorganic diphosphatase activity
FORC53_1807	COG0243	molybdopterin cofactor binding
FORC53_1808	COG3005	denitrification pathway
FORC53_1809	COG4459	periplasmic nitrate reductase
FORC53_1810	COG0390	transport system, permease component
FORC53_1811	COG0390	transport system, permease component
FORC53_1812	COG2116	formate transmembrane transporter activity
FORC53_1816	COG0583	DNA-binding transcription factor activity
FORC53_1817	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC53_1819	COG1435	thymidine kinase activity
FORC53_1821	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC53_1822	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC53_1823	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FORC53_1825	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FORC53_1825	COG0140	phosphoribosyl-ATP diphosphatase activity
FORC53_1826	COG0107	imidazoleglycerol-phosphate synthase activity
FORC53_1827	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FORC53_1828	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FORC53_1829	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC53_1829	COG0131	Imidazoleglycerol-phosphate dehydratase
FORC53_1830	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FORC53_1833	COG1757	Na H antiporter
FORC53_1835	COG2916	Histone family protein nucleoid-structuring protein H-NS
FORC53_1836	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC53_1838	COG0482	sulfurtransferase activity
FORC53_1840	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FORC53_1844	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FORC53_1847	COG1028	Short-chain dehydrogenase reductase Sdr
FORC53_1849	COG0501	Belongs to the peptidase M48B family
FORC53_1857	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FORC53_1861	COG0686	Belongs to the AlaDH PNT family
FORC53_1863	COG0583	DNA-binding transcription factor activity
FORC53_1867	COG3385	transposase activity
FORC53_1870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC53_1871	COG3108	Peptidase M15
FORC53_1872	COG2989	Protein conserved in bacteria
FORC53_1880	COG4608	Belongs to the ABC transporter superfamily
FORC53_1881	COG0444	Belongs to the ABC transporter superfamily
FORC53_1882	COG4166	transmembrane transport
FORC53_1883	COG4239	(ABC) transporter, permease
FORC53_1884	COG4174	ABC transporter (Permease)
FORC53_1887	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FORC53_1888	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FORC53_1890	COG0539	negative regulation of cytoplasmic translation
FORC53_1892	COG0616	signal peptide processing
FORC53_1893	COG1028	Short-chain dehydrogenase reductase Sdr
FORC53_1896	COG0587	DNA-directed DNA polymerase activity
FORC53_1897	COG0835	chemotaxis
FORC53_1897	COG0784	Response regulator, receiver
FORC53_1898	COG1940	carbohydrate kinase activity
FORC53_1899	COG0469	pyruvate kinase activity
FORC53_1900	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC53_1902	COG0733	neurotransmitter:sodium symporter activity
FORC53_1904	COG1263	PTS System
FORC53_1904	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC53_1905	COG0084	hydrolase, TatD family'
FORC53_1908	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FORC53_1914	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC53_1917	COG1399	metal-binding, possibly nucleic acid-binding protein
FORC53_1920	COG1530	ribonuclease E activity
FORC53_1921	COG0659	secondary active sulfate transmembrane transporter activity
FORC53_1922	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FORC53_1923	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FORC53_1927	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC53_1927	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC53_1930	COG3088	subunit of a heme lyase
FORC53_1931	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC53_1932	COG1138	Cytochrome C-type biogenesis protein
FORC53_1933	COG3301	Polysulphide reductase, NrfD
FORC53_1934	COG0437	4 iron, 4 sulfur cluster binding
FORC53_1935	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FORC53_1942	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC53_1943	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC53_1953	COG2197	response regulator
FORC53_1954	COG0417	DNA replication proofreading
FORC53_1955	COG5001	Diguanylate cyclase
FORC53_1961	COG0009	L-threonylcarbamoyladenylate synthase
FORC53_1962	COG0613	PHP domain protein
FORC53_1963	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORC53_1964	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC53_1966	COG0135	phosphoribosylanthranilate isomerase activity
FORC53_1966	COG0134	indole-3-glycerol-phosphate synthase activity
FORC53_1969	COG1301	dicarboxylic acid transport
FORC53_1972	COG1607	acyl-coa hydrolase
FORC53_1973	COG2350	Protein conserved in bacteria
FORC53_1975	COG0435	Glutathione S-transferase
FORC53_1977	COG0444	Belongs to the ABC transporter superfamily
FORC53_1978	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC53_1979	COG0601	transmembrane transport
FORC53_1982	COG0314	molybdopterin synthase activity
FORC53_1983	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FORC53_1985	COG0521	Mo-molybdopterin cofactor biosynthetic process
FORC53_1987	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FORC53_1993	COG4656	Part of a membrane complex involved in electron transport
FORC53_1996	COG4659	FMN binding
FORC53_1998	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FORC53_1999	COG0346	lactoylglutathione lyase activity
FORC53_2001	COG2885	chlorophyll binding
FORC53_2002	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC53_2003	COG2056	Na+-H+ antiporter family
FORC53_2005	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FORC53_2008	COG1028	Short-chain dehydrogenase reductase Sdr
FORC53_2009	COG1012	belongs to the aldehyde dehydrogenase family
FORC53_2009	COG1454	alcohol dehydrogenase
FORC53_2010	COG2095	MarC family integral membrane protein
FORC53_2011	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC53_2013	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC53_2014	COG1757	Na H antiporter
FORC53_2017	COG3081	Nucleoid-associated protein
FORC53_2019	COG3083	sulfuric ester hydrolase activity
FORC53_2020	COG0569	domain protein
FORC53_2021	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC53_2022	COG2731	YhcH YjgK YiaL family protein
FORC53_2024	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC53_2025	COG3706	GGDEF domain
FORC53_2025	COG0745	RESPONSE REGULATOR receiver
FORC53_2028	COG0123	including yeast histone deacetylase and acetoin utilization protein
FORC53_2029	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC53_2030	COG0778	Nitroreductase
FORC53_2031	COG1902	pentaerythritol trinitrate reductase activity
FORC53_2031	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC53_2032	COG0616	signal peptide processing
FORC53_2033	COG0252	asparaginase activity
FORC53_2034	COG3139	Protein of unknown function (DUF1315)
FORC53_2037	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC53_2043	COG5001	Diguanylate cyclase
FORC53_2046	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FORC53_2047	COG1946	Acyl-CoA thioesterase
FORC53_2049	COG1522	sequence-specific DNA binding
FORC53_2050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC53_2053	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC53_2054	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC53_2060	COG0318	PFAM AMP-dependent synthetase and ligase
FORC53_2061	COG1441	menaquinone biosynthetic process
FORC53_2062	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FORC53_2065	COG1169	isochorismate synthase
FORC53_2066	COG0436	Aminotransferase
FORC53_2067	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FORC53_2071	COG1555	photosystem II stabilization
FORC53_2072	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC53_2073	COG0776	regulation of translation
FORC53_2074	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FORC53_2079	COG4191	Histidine kinase
FORC53_2080	COG2204	response regulator
FORC53_2082	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FORC53_2083	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC53_2084	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FORC53_2085	COG3842	ATPase activity
FORC53_2090	COG0745	RESPONSE REGULATOR receiver
FORC53_2101	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC53_2102	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC53_2104	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FORC53_2106	COG1216	Glycosyl transferase, family 2
FORC53_2107	COG2986	histidine ammonia-lyase
FORC53_2113	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC53_2115	COG1028	Short-chain dehydrogenase reductase Sdr
FORC53_2117	COG5002	protein histidine kinase activity
FORC53_2118	COG0745	RESPONSE REGULATOR receiver
FORC53_2120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC53_2122	COG2951	lytic endotransglycosylase activity
FORC53_2125	COG2894	cell division
FORC53_2127	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FORC53_2128	COG0318	PFAM AMP-dependent synthetase and ligase
FORC53_2129	COG0596	Alpha beta hydrolase
FORC53_2132	COG1214	PFAM Peptidase M22, glycoprotease
FORC53_2133	COG1199	ATP-dependent helicase activity
FORC53_2135	COG0788	formyltetrahydrofolate deformylase activity
FORC53_2136	COG3102	Protein conserved in bacteria
FORC53_2140	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FORC53_2141	COG1918	ferrous iron import across plasma membrane
FORC53_2143	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FORC53_2145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC53_2148	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC53_2149	COG0567	Dehydrogenase, E1 component
FORC53_2151	COG1053	succinate dehydrogenase
FORC53_2152	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FORC53_2153	COG2009	succinate dehydrogenase
FORC53_2155	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FORC53_2157	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC53_2159	COG0251	oxidation-reduction process
FORC53_2160	COG2964	Protein conserved in bacteria
FORC53_2161	COG0033	Phosphoglucomutase
FORC53_2162	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FORC53_2163	COG0596	Alpha beta hydrolase
FORC53_2165	COG0716	FMN binding
FORC53_2168	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC53_2169	COG1263	PTS System
FORC53_2169	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC53_2169	COG2190	(PTS) system
FORC53_2170	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC53_2171	COG1846	Transcriptional regulator
FORC53_2171	COG1940	carbohydrate kinase activity
FORC53_2172	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC53_2172	COG4651	solute:proton antiporter activity
FORC53_2173	COG0367	asparagine synthase
FORC53_2175	COG3104	oligopeptide transport
FORC53_2176	COG0840	transmembrane signaling receptor activity
FORC53_2177	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FORC53_2179	COG0326	Molecular chaperone. Has ATPase activity
FORC53_2180	COG3710	Transcriptional regulator
FORC53_2184	COG0622	Phosphoesterase
FORC53_2189	COG1090	epimerase
FORC53_2190	COG0300	oxidoreductase activity
FORC53_2191	COG3118	belongs to the thioredoxin family
FORC53_2192	COG0330	HflC and HflK could
FORC53_2198	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FORC53_2199	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC53_2200	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC53_2201	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FORC53_2202	COG2190	(PTS) system
FORC53_2203	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC53_2204	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC53_2207	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC53_2208	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC53_2210	COG3951	Flagellar rod assembly protein muramidase FlgJ
FORC53_2210	COG1705	Flagellar rod assembly protein muramidase FlgJ
FORC53_2212	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FORC53_2213	COG4786	Flagellar basal body rod
FORC53_2214	COG4787	bacterial-type flagellum-dependent cell motility
FORC53_2215	COG1749	Flagellar hook protein flgE
FORC53_2216	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FORC53_2217	COG1558	bacterial-type flagellum-dependent cell motility
FORC53_2218	COG1815	bacterial-type flagellum-dependent cell motility
FORC53_2219	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC53_2220	COG0784	Response regulator, receiver
FORC53_2220	COG0835	chemotaxis
FORC53_2232	COG2217	Heavy metal translocating P-type atpase
FORC53_2232	COG2608	mercury ion transmembrane transporter activity
FORC53_2235	COG3735	TraB family
FORC53_2236	COG2840	Smr protein MutS2
FORC53_2237	COG1187	pseudouridine synthase activity
FORC53_2241	COG2912	Transglutaminase-like superfamily
FORC53_2242	COG3094	Invasion gene expression up-regulator, SirB
FORC53_2243	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC53_2245	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FORC53_2253	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC53_2255	COG1702	phosphate starvation-inducible protein PhoH
FORC53_2256	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FORC53_2257	COG4535	Mg2 and Co2 transporter CorC
FORC53_2258	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FORC53_2259	COG2888	peptidyl-tyrosine sulfation
FORC53_2261	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FORC53_2262	COG1466	dna polymerase III delta subunit
FORC53_2263	COG0799	negative regulation of ribosome biogenesis
FORC53_2265	COG0768	penicillin binding
FORC53_2266	COG0772	Belongs to the SEDS family
FORC53_2267	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FORC53_2268	COG1686	Belongs to the peptidase S11 family
FORC53_2270	COG0321	lipoyl(octanoyl) transferase activity
FORC53_2279	COG0366	Alpha amylase catalytic
FORC53_2280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC53_2280	COG1263	PTS System
FORC53_2282	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC53_2283	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FORC53_2284	COG2011	ABC-type metal ion transport system permease component
FORC53_2285	COG1464	Belongs to the NlpA lipoprotein family
FORC53_2286	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FORC53_2290	COG3706	GGDEF domain
FORC53_2291	COG1611	Belongs to the LOG family
FORC53_2295	COG2363	Small membrane protein
FORC53_2297	COG0583	DNA-binding transcription factor activity
FORC53_2302	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FORC53_2304	COG0142	geranyltranstransferase activity
FORC53_2305	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FORC53_2306	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FORC53_2307	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FORC53_2312	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC53_2312	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC53_2313	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FORC53_2319	COG2252	PERMEase
FORC53_2320	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC53_2327	COG0590	tRNA wobble adenosine to inosine editing
FORC53_2328	COG0583	DNA-binding transcription factor activity
FORC53_2329	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FORC53_2330	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FORC53_2331	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FORC53_2344	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FORC53_2345	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FORC53_2346	COG0497	DNA recombination
FORC53_2347	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC53_2349	COG2867	negative regulation of translational initiation
FORC53_2359	COG0009	L-threonylcarbamoyladenylate synthase
FORC53_2363	COG0583	DNA-binding transcription factor activity
FORC53_2364	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC53_2365	COG1115	amino acid carrier protein
FORC53_2366	COG1584	GPR1 FUN34 yaaH family protein
FORC53_2368	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FORC53_2368	COG0519	Catalyzes the synthesis of GMP from XMP
FORC53_2369	COG0516	GMP reductase activity
FORC53_2369	COG0517	IMP dehydrogenase activity
FORC53_2370	COG1570	exodeoxyribonuclease VII activity
FORC53_2372	COG2199	diguanylate cyclase activity
FORC53_2372	COG2203	Gaf domain
FORC53_2375	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC53_2376	COG2976	Protein conserved in bacteria
FORC53_2381	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FORC53_2384	COG2975	iron-sulfur cluster assembly
FORC53_2385	COG0633	Ferredoxin
FORC53_2389	COG0822	iron-sulfur transferase activity
FORC53_2392	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FORC53_2393	COG0483	inositol monophosphate 1-phosphatase activity
FORC53_2396	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC53_2397	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC53_2398	COG1862	Preprotein translocase
FORC53_2403	COG0517	IMP dehydrogenase activity
FORC53_2405	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FORC53_2406	COG0583	DNA-binding transcription factor activity
FORC53_2407	COG0450	alkyl hydroperoxide reductase
FORC53_2414	COG0704	Plays a role in the regulation of phosphate uptake
FORC53_2416	COG0581	inorganic phosphate transmembrane transporter activity
FORC53_2417	COG0573	inorganic phosphate transmembrane transporter activity
FORC53_2418	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FORC53_2419	COG0248	Ppx GppA phosphatase
FORC53_2421	COG5002	protein histidine kinase activity
FORC53_2422	COG0745	RESPONSE REGULATOR receiver
FORC53_2425	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC53_2431	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC53_2432	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC53_2433	COG0077	Prephenate dehydratase
FORC53_2433	COG1605	Chorismate mutase
FORC53_2434	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FORC53_2437	COG0488	(ABC) transporter
FORC53_2439	COG0739	heme binding
FORC53_2440	COG1605	Chorismate mutase
FORC53_2440	COG0287	Prephenate dehydrogenase
FORC53_2441	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC53_2442	COG1472	Belongs to the glycosyl hydrolase 3 family
FORC53_2447	COG1966	Carbon starvation protein
FORC53_2448	COG3275	phosphorelay sensor kinase activity
FORC53_2451	COG1047	Peptidyl-prolyl cis-trans
FORC53_2453	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FORC53_2454	COG0196	riboflavin kinase activity
FORC53_2455	COG0728	peptidoglycan biosynthetic process
FORC53_2457	COG0640	Transcriptional regulator
FORC53_2458	COG0583	DNA-binding transcription factor activity
FORC53_2459	COG1283	sodium-dependent phosphate transmembrane transporter activity
FORC53_2463	COG0730	response to heat
FORC53_2468	COG0667	Aldo Keto reductase
FORC53_2472	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FORC53_2473	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FORC53_2474	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC53_2476	COG0716	FMN binding
FORC53_2478	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FORC53_2479	COG0513	Belongs to the DEAD box helicase family
FORC53_2481	COG1115	amino acid carrier protein
FORC53_2487	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FORC53_2494	COG0745	RESPONSE REGULATOR receiver
FORC53_2496	COG2198	Histidine kinase
FORC53_2496	COG0784	Response regulator, receiver
FORC53_2496	COG5002	protein histidine kinase activity
FORC53_2497	COG4251	negative regulation of phosphorylation
FORC53_2497	COG3706	GGDEF domain
FORC53_2497	COG2203	Gaf domain
FORC53_2497	COG5001	Diguanylate cyclase
FORC53_2498	COG1242	4 iron, 4 sulfur cluster binding
FORC53_2499	COG0067	glutamate synthase
FORC53_2499	COG0069	glutamate synthase activity
FORC53_2499	COG0070	glutamate synthase
FORC53_2501	COG0069	glutamate synthase activity
FORC53_2501	COG0070	glutamate synthase
FORC53_2501	COG0067	glutamate synthase
FORC53_2502	COG0493	'glutamate synthase
FORC53_2504	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FORC53_2506	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC53_2507	COG2860	membrane
FORC53_2508	COG0583	DNA-binding transcription factor activity
FORC53_2509	COG0730	response to heat
FORC53_2512	COG0505	Belongs to the CarA family
FORC53_2514	COG0494	nUDIX hydrolase
FORC53_2515	COG0653	protein targeting
FORC53_2518	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FORC53_2519	COG0849	cell division
FORC53_2520	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FORC53_2521	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC53_2523	COG0772	Belongs to the SEDS family
FORC53_2524	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FORC53_2526	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORC53_2527	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FORC53_2529	COG0768	penicillin binding
FORC53_2530	COG3116	cell division
FORC53_2532	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FORC53_2533	COG3107	peptidoglycan biosynthetic process
FORC53_2535	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FORC53_2536	COG2823	Periplasmic or secreted lipoprotein
FORC53_2537	COG2969	positive regulation of protein catabolic process
FORC53_2538	COG0625	glutathione transferase activity
FORC53_2539	COG2857	Cytochrome c1
FORC53_2540	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FORC53_2541	COG0723	plastoquinol--plastocyanin reductase activity
FORC53_2544	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FORC53_2545	COG3105	Protein conserved in bacteria
FORC53_2546	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC53_2547	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC53_2549	COG0187	DNA topoisomerase II activity
FORC53_2550	COG3150	esterase
FORC53_2552	COG3151	Protein conserved in bacteria
FORC53_2553	COG0494	nUDIX hydrolase
FORC53_2554	COG1538	Outer membrane efflux protein
FORC53_2558	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC53_2559	COG3025	triphosphatase activity
FORC53_2560	COG1392	Phosphate transport regulator
FORC53_2561	COG0306	phosphate transporter
FORC53_2562	COG4991	sh3 domain protein
FORC53_2563	COG3267	Type II secretory pathway component ExeA
FORC53_2563	COG3409	Peptidoglycan-binding domain 1 protein
FORC53_2564	COG0617	tRNA 3'-terminal CCA addition
FORC53_2566	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC53_2567	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FORC53_2569	COG0596	Alpha beta hydrolase
FORC53_2572	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FORC53_2573	COG1610	YqeY-like protein
FORC53_2575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORC53_2576	COG0582	viral genome integration into host DNA
FORC53_2585	COG3339	Conserved Protein
FORC53_2588	COG2003	Belongs to the UPF0758 family
FORC53_2597	COG1518	maintenance of DNA repeat elements
FORC53_2602	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FORC53_2603	COG2213	PTS system mannitol-specific
FORC53_2603	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC53_2605	COG3722	fumarate hydratase activity
FORC53_2606	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FORC53_2607	COG1349	DNA-binding transcription factor activity
FORC53_2608	COG0469	pyruvate kinase activity
FORC53_2610	COG3706	GGDEF domain
FORC53_2611	COG0440	acetolactate synthase activity
FORC53_2612	COG0028	Belongs to the TPP enzyme family
FORC53_2613	COG1022	Amp-dependent synthetase and ligase
FORC53_2619	COG0473	3-isopropylmalate dehydrogenase activity
FORC53_2621	COG0066	3-isopropylmalate dehydratase activity
FORC53_2624	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FORC53_2632	COG3610	response to peptide
FORC53_2633	COG2966	Psort location CytoplasmicMembrane, score
FORC53_2636	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FORC53_2637	COG0142	geranyltranstransferase activity
FORC53_2638	COG0039	L-malate dehydrogenase activity
FORC53_2642	COG0589	response to stress
FORC53_2643	COG0204	Acyl-transferase
FORC53_2644	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FORC53_2645	COG5007	Belongs to the BolA IbaG family
FORC53_2647	COG2854	intermembrane phospholipid transfer
FORC53_2648	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FORC53_2649	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FORC53_2650	COG1127	ABC transporter
FORC53_2652	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FORC53_2652	COG0517	IMP dehydrogenase activity
FORC53_2653	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FORC53_2655	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FORC53_2656	COG1137	ATPase activity
FORC53_2658	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC53_2659	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC53_2660	COG1660	Displays ATPase and GTPase activities
FORC53_2661	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC53_2662	COG2239	Acts as a magnesium transporter
FORC53_2663	COG0312	modulator of DNA gyrase
FORC53_2664	COG3028	Belongs to the UPF0307 family
FORC53_2666	COG1178	ABC-type Fe3 transport system permease component
FORC53_2667	COG4143	(ABC) transporter
FORC53_2668	COG0163	prenyltransferase activity
FORC53_2669	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC53_2673	COG2105	PFAM AIG2 family protein
FORC53_2674	COG2911	Protein conserved in bacteria
FORC53_2675	COG0729	surface antigen
FORC53_2678	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FORC53_2682	COG1136	(ABC) transporter
FORC53_2682	COG0577	efflux transmembrane transporter activity
FORC53_2687	COG0471	metal ion transport
FORC53_2687	COG3273	potassium ion transport
FORC53_2690	COG1648	precorrin-2 dehydrogenase activity
FORC53_2690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC53_2691	COG0737	Belongs to the 5'-nucleotidase family
FORC53_2693	COG2153	protein acetylation
FORC53_2695	COG3266	domain, Protein
FORC53_2695	COG3061	Opacity-associated protein A
FORC53_2696	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC53_2701	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FORC53_2703	COG0201	protein transport
FORC53_2723	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FORC53_2726	COG3064	Membrane
FORC53_2727	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FORC53_2729	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FORC53_2730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORC53_2731	COG1482	cell wall glycoprotein biosynthetic process
FORC53_2734	COG0438	transferase activity, transferring glycosyl groups
FORC53_2737	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FORC53_2739	COG0647	UMP catabolic process
FORC53_2749	COG1596	polysaccharide export
FORC53_2757	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC53_2759	COG1560	Kdo2-lipid A biosynthetic process
FORC53_2760	COG0859	PFAM glycosyl transferase family 9
FORC53_2761	COG1519	Transferase
FORC53_2767	COG0318	PFAM AMP-dependent synthetase and ligase
FORC53_2770	COG1028	Short-chain dehydrogenase reductase Sdr
FORC53_2771	COG1083	cytidylyl-transferase
FORC53_2773	COG0673	inositol 2-dehydrogenase activity
FORC53_2776	COG2089	acid synthase
FORC53_2777	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FORC53_2778	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FORC53_2781	COG3083	sulfuric ester hydrolase activity
FORC53_2782	COG3642	lipopolysaccharide core region biosynthetic process
FORC53_2783	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC53_2784	COG0859	PFAM glycosyl transferase family 9
FORC53_2785	COG0463	Glycosyl transferase, family 2
FORC53_2786	COG0859	PFAM glycosyl transferase family 9
FORC53_2793	COG2003	Belongs to the UPF0758 family
FORC53_2794	COG0840	transmembrane signaling receptor activity
FORC53_2795	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FORC53_2797	COG1560	Kdo2-lipid A biosynthetic process
FORC53_2800	COG1561	YicC-like family, N-terminal region
FORC53_2804	COG4608	Belongs to the ABC transporter superfamily
FORC53_2805	COG0444	Belongs to the ABC transporter superfamily
FORC53_2806	COG0747	negative chemotaxis
FORC53_2807	COG4239	(ABC) transporter, permease
FORC53_2808	COG4174	ABC transporter (Permease)
FORC53_2809	COG4206	TonB-dependent receptor
FORC53_2811	COG0811	peptide transport
FORC53_2812	COG0811	peptide transport
FORC53_2813	COG0848	biopolymer transport protein
FORC53_2818	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC53_2819	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC53_2820	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FORC53_2821	COG2233	PERMEase
FORC53_2823	COG0745	RESPONSE REGULATOR receiver
FORC53_2825	COG2183	response to ionizing radiation
FORC53_2827	COG0596	Alpha beta hydrolase
FORC53_2828	COG1040	competence protein
FORC53_2830	COG0494	nUDIX hydrolase
FORC53_2831	COG1218	3'(2'),5'-bisphosphate nucleotidase
FORC53_2833	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FORC53_2834	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FORC53_2835	COG3156	type II secretion system protein K
FORC53_2836	COG4795	General secretion pathway protein
FORC53_2837	COG2165	general secretion pathway protein
FORC53_2838	COG2165	general secretion pathway protein
FORC53_2839	COG2165	general secretion pathway protein
FORC53_2840	COG1459	type II secretion system
FORC53_2841	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC53_2843	COG3031	protein transport across the cell outer membrane
FORC53_2844	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FORC53_2848	COG0456	acetyltransferase
FORC53_2850	COG1295	ribonuclease BN
FORC53_2852	COG1660	Displays ATPase and GTPase activities
FORC53_2854	COG0174	glutamine synthetase
FORC53_2856	COG3852	Histidine kinase
FORC53_2857	COG2204	response regulator
FORC53_2858	COG5001	Diguanylate cyclase
FORC53_2858	COG3300	MHYT domain
FORC53_2859	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC53_2865	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC53_2865	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC53_2867	COG0084	hydrolase, TatD family'
FORC53_2868	COG0805	protein transport
FORC53_2870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORC53_2872	COG3165	ubiquinone biosynthetic process from chorismate
FORC53_2874	COG1322	Protein conserved in bacteria
FORC53_2877	COG3335	DDE superfamily endonuclease
FORC53_2884	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FORC53_2885	COG3118	belongs to the thioredoxin family
FORC53_2888	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FORC53_2890	COG0514	ATP-dependent DNA helicase (RecQ)
FORC53_2891	COG2962	Rard protein
FORC53_2893	COG1280	lysine exporter protein (LysE YggA)
FORC53_2894	COG0210	DNA helicase
FORC53_2902	COG0006	proline dipeptidase activity
FORC53_2902	COG0006	proline dipeptidase activity
FORC53_2906	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC53_2910	COG2132	Multicopper oxidase
FORC53_2912	COG3335	DDE superfamily endonuclease
FORC53_2915	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FORC53_2922	COG0551	DNA topoisomerase type I activity
FORC53_2924	COG0758	DNA mediated transformation
FORC53_2929	COG0569	domain protein
FORC53_2930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC53_2931	COG1272	protein, Hemolysin III
FORC53_2932	COG4326	sporulation control protein
FORC53_2934	COG3084	Protein conserved in bacteria
FORC53_2936	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FORC53_2937	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC53_2938	COG0204	Acyl-transferase
FORC53_2940	COG0606	chelatase, subunit chli
FORC53_2942	COG3978	acetolactate synthase activity
FORC53_2943	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC53_2946	COG0583	DNA-binding transcription factor activity
FORC53_2947	COG2814	Major facilitator Superfamily
FORC53_2949	COG0765	amino acid transport
FORC53_2950	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FORC53_2956	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FORC53_2959	COG3312	ion transport
FORC53_2960	COG1475	DNA binding
FORC53_2961	COG1192	Involved in chromosome partitioning
FORC53_2963	COG0445	tRNA wobble uridine modification
FORC53_2964	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FORC53_2966	COG0706	membrane insertase activity
FORC53_2968	COG1126	abc transporter atp-binding protein
FORC53_2973	COG4608	Belongs to the ABC transporter superfamily
FORC53_2974	COG0444	Belongs to the ABC transporter superfamily
FORC53_2976	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC53_2976	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FORC53_2980	COG0217	transcriptional regulatory protein
FORC53_2982	COG0583	DNA-binding transcription factor activity
FORC53_2984	COG1136	(ABC) transporter
FORC53_2985	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC53_2988	COG3275	phosphorelay sensor kinase activity
FORC53_2992	COG0786	glutamate:sodium symporter activity
FORC53_2993	COG3385	transposase activity
FORC53_2995	COG0786	glutamate:sodium symporter activity
FORC53_3000	COG0189	ligase activity
FORC53_3004	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC53_3005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC53_3006	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC53_3010	COG1309	transcriptional regulator
FORC53_3015	COG1741	Belongs to the pirin family
FORC53_3017	COG5001	Diguanylate cyclase
FORC53_3018	COG3706	GGDEF domain
FORC53_3028	COG1982	Orn Lys Arg decarboxylase major
FORC53_3029	COG0531	amino acid
FORC53_3030	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FORC53_3036	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC53_3037	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FORC53_3038	COG1162	GTPase activity
FORC53_3039	COG2847	Copper chaperone PCu(A)C
FORC53_3040	COG1999	signal sequence binding
FORC53_3047	COG0058	SHG alpha-glucan phosphorylase activity
FORC53_3048	COG1640	4-alpha-glucanotransferase
FORC53_3051	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC53_3059	COG0560	Phosphoserine phosphatase
FORC53_3063	COG1012	belongs to the aldehyde dehydrogenase family
FORC53_3064	COG0625	glutathione transferase activity
FORC53_3065	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC53_3066	COG1283	sodium-dependent phosphate transmembrane transporter activity
FORC53_3067	COG0612	Peptidase, M16
FORC53_3069	COG0583	DNA-binding transcription factor activity
FORC53_3070	COG0583	DNA-binding transcription factor activity
FORC53_3072	COG0387	Pfam Sodium calcium exchanger
FORC53_3073	COG0586	Pfam SNARE associated Golgi protein
FORC53_3075	COG0642	Histidine kinase
FORC53_3076	COG0745	RESPONSE REGULATOR receiver
FORC53_3077	COG2199	diguanylate cyclase activity
FORC53_3081	COG1609	Transcriptional regulator
FORC53_3084	COG0395	ABC-type sugar transport system, permease component
FORC53_3087	COG1609	Transcriptional regulator
FORC53_3089	COG0747	negative chemotaxis
FORC53_3091	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC53_3092	COG0444	Belongs to the ABC transporter superfamily
FORC53_3093	COG4608	Belongs to the ABC transporter superfamily
FORC53_3095	COG1609	Transcriptional regulator
FORC53_3098	COG4580	involved in the transport of maltose and maltodextrins
FORC53_3100	COG1472	Belongs to the glycosyl hydrolase 3 family
FORC53_3101	COG0534	Mate efflux family protein
FORC53_3103	COG1566	PFAM secretion protein HlyD family protein
FORC53_3112	COG0564	pseudouridine synthase activity
FORC53_3113	COG3706	GGDEF domain
FORC53_3117	COG1609	Transcriptional regulator
FORC53_3119	COG1129	ABC transporter
FORC53_3123	COG4580	involved in the transport of maltose and maltodextrins
FORC53_3126	COG2211	Major facilitator Superfamily
FORC53_3128	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC53_3130	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FORC53_3132	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FORC53_3134	COG3708	Transcriptional regulator
FORC53_3134	COG2207	Transcriptional regulator
FORC53_3144	COG1482	cell wall glycoprotein biosynthetic process
FORC53_3145	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC53_3145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC53_3145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC53_3146	COG2207	Transcriptional regulator
FORC53_3148	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC53_3149	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC53_3151	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC53_3153	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC53_3157	COG3383	formate dehydrogenase (NAD+) activity
FORC53_3159	COG0583	DNA-binding transcription factor activity
FORC53_3160	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FORC53_3164	COG0768	penicillin binding
FORC53_3167	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FORC53_3171	COG0583	DNA-binding transcription factor activity
FORC53_3174	COG0137	argininosuccinate synthase activity
FORC53_3176	COG1301	dicarboxylic acid transport
FORC53_3186	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC53_3187	COG2175	clavaminate synthase activity
FORC53_3193	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC53_3195	COG3706	GGDEF domain
FORC53_3198	COG2356	endonuclease I
FORC53_3201	COG1368	sulfuric ester hydrolase activity
FORC53_3202	COG2194	sulfuric ester hydrolase activity
FORC53_3203	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC53_3204	COG2205	protein histidine kinase activity
FORC53_3205	COG0745	RESPONSE REGULATOR receiver
FORC53_3209	COG4221	oxidoreductase activity
FORC53_3214	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC53_3215	COG0076	glutamate decarboxylase activity
FORC53_3218	COG0561	phosphatase activity
FORC53_3221	COG0671	phosphoesterase, PA-phosphatase related
FORC53_3222	COG0351	phosphomethylpyrimidine kinase
FORC53_3231	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC53_3232	COG4771	TonB-dependent receptor
FORC53_3236	COG0393	Putative heavy-metal-binding
FORC53_3239	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC53_3249	COG0346	lactoylglutathione lyase activity
FORC53_3251	COG2211	Major facilitator Superfamily
FORC53_3254	COG3240	lipase activity
FORC53_3270	COG0582	viral genome integration into host DNA
FORC53_3272	COG3040	lipid binding
FORC53_3279	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FORC53_3281	COG2197	response regulator
FORC53_3285	COG2205	protein histidine kinase activity
FORC53_3285	COG0784	Response regulator, receiver
FORC53_3286	COG3111	PFAM Bacterial OB fold (BOF) protein
FORC53_3288	COG2274	protein secretion by the type I secretion system
FORC53_3290	COG1538	Outer membrane efflux protein
FORC53_3294	COG0668	transmembrane transport
FORC53_3300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC53_3301	COG4946	Tricorn protease homolog
FORC53_3301	COG0793	Belongs to the peptidase S41A family
FORC53_3304	COG1122	ATPase activity
FORC53_3305	COG4720	Psort location CytoplasmicMembrane, score
FORC53_3306	COG1566	PFAM secretion protein HlyD family protein
FORC53_3308	COG3706	GGDEF domain
FORC53_3312	COG3272	Protein of unknown function (DUF1722)
FORC53_3313	COG0789	Transcriptional regulator
FORC53_3314	COG0415	Belongs to the DNA photolyase family
FORC53_3315	COG1388	LysM domain
FORC53_3315	COG1376	ErfK ybiS ycfS ynhG family protein
FORC53_3317	COG0513	Belongs to the DEAD box helicase family
FORC53_3325	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC53_3326	COG0573	inorganic phosphate transmembrane transporter activity
FORC53_3327	COG0581	inorganic phosphate transmembrane transporter activity
FORC53_3329	COG2203	Gaf domain
FORC53_3329	COG3706	GGDEF domain
FORC53_3329	COG4251	negative regulation of phosphorylation
FORC53_3329	COG5001	Diguanylate cyclase
FORC53_3331	COG2304	oxidoreductase activity
FORC53_3335	COG0714	Associated with various cellular activities
FORC53_3349	COG1596	polysaccharide export
FORC53_3351	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC53_3361	COG2354	Protein conserved in bacteria
FORC53_3364	COG0633	Ferredoxin
FORC53_3364	COG3217	Mosc domain protein beta barrel domain protein
FORC53_3364	COG0633	Ferredoxin
FORC53_3364	COG3217	Mosc domain protein beta barrel domain protein
FORC53_3365	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FORC53_3374	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FORC53_3375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC53_3377	COG0848	biopolymer transport protein
FORC53_3378	COG0811	peptide transport
FORC53_3379	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FORC53_3381	COG3721	Heme iron utilization protein
FORC53_3382	COG0748	coenzyme F420 binding
FORC53_3384	COG0835	chemotaxis
FORC53_3384	COG0784	Response regulator, receiver
FORC53_3385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC53_3386	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FORC53_3392	COG0328	RNA-DNA hybrid ribonuclease activity
FORC53_3395	COG0589	response to stress
FORC53_3396	COG0366	Alpha amylase catalytic
FORC53_3398	COG0840	transmembrane signaling receptor activity
FORC53_3405	COG0739	heme binding
FORC53_3407	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FORC53_3409	COG2084	Dehydrogenase
FORC53_3413	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC53_3417	COG0840	transmembrane signaling receptor activity
FORC53_3420	COG3706	GGDEF domain
FORC53_3421	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC53_3421	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC53_3422	COG1765	OsmC-like protein
FORC53_3423	COG2171	N-acyltransferase activity
FORC53_3427	COG1011	Hydrolase
FORC53_3430	COG0840	transmembrane signaling receptor activity
FORC53_3432	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC53_3437	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC53_3441	COG3842	ATPase activity
FORC53_3445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC53_3446	COG0583	DNA-binding transcription factor activity
FORC53_3449	COG1760	l-serine dehydratase
FORC53_3453	COG1686	Belongs to the peptidase S11 family
FORC53_3458	COG1012	belongs to the aldehyde dehydrogenase family
FORC53_3459	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FORC53_3462	COG4175	Glycine betaine
FORC53_3463	COG3059	membrane
FORC53_3470	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC53_3471	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
FORC53_3473	COG0247	lactate metabolic process
FORC53_3476	COG1619	proteins homologs of microcin C7 resistance protein MccF
FORC53_3477	COG2133	pyrroloquinoline quinone binding
FORC53_3479	COG1454	alcohol dehydrogenase
FORC53_3480	COG0443	Heat shock 70 kDa protein
FORC53_3481	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC53_3487	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC53_3488	COG3174	membrane
FORC53_3493	COG0814	amino acid
FORC53_3494	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FORC53_3499	COG2962	Rard protein
FORC53_3502	COG0671	phosphoesterase, PA-phosphatase related
FORC53_3504	COG1288	antiporter activity
FORC53_3507	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FORC53_3510	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FORC53_3511	COG2315	Protein conserved in bacteria
FORC53_3517	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC53_3518	COG1879	ABC-type sugar transport system periplasmic component
FORC53_3519	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC53_3520	COG1609	Transcriptional regulator
FORC53_3522	COG0784	Response regulator, receiver
FORC53_3522	COG0835	chemotaxis
FORC53_3524	COG0456	acetyltransferase
FORC53_3527	COG1366	Belongs to the anti-sigma-factor antagonist family
FORC53_3529	COG2172	sigma factor antagonist activity
FORC53_3532	COG3437	response regulator, receiver
FORC53_3533	COG0420	3'-5' exonuclease activity
FORC53_3534	COG0419	ATPase involved in DNA repair
FORC53_3536	COG0583	DNA-binding transcription factor activity
FORC53_3540	COG4964	Belongs to the GSP D family
FORC53_3555	COG0471	metal ion transport
FORC53_3557	COG3290	protein histidine kinase activity
FORC53_3559	COG0110	maltose O-acetyltransferase activity
FORC53_3565	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC53_3566	COG4605	iron ion homeostasis
FORC53_3567	COG4604	ABC transporter, ATP-binding protein
FORC53_3568	COG0789	Transcriptional regulator
FORC53_3574	COG1289	transmembrane transporter activity
FORC53_3575	COG0210	DNA helicase
FORC53_3577	COG1879	ABC-type sugar transport system periplasmic component
FORC53_3578	COG2198	Histidine kinase
FORC53_3578	COG0784	Response regulator, receiver
FORC53_3578	COG2205	protein histidine kinase activity
FORC53_3582	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FORC53_3583	COG3005	denitrification pathway
FORC53_3588	COG0513	Belongs to the DEAD box helicase family
FORC53_3590	COG1716	ATPase activity
FORC53_3590	COG5001	Diguanylate cyclase
FORC53_3595	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC53_3598	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FORC53_3599	COG0513	Belongs to the DEAD box helicase family
FORC53_3601	COG0457	Tetratricopeptide repeat
FORC53_3602	COG2814	Major facilitator Superfamily
FORC53_3602	COG0477	Major facilitator Superfamily
FORC53_3603	COG1940	carbohydrate kinase activity
FORC53_3604	COG2017	converts alpha-aldose to the beta-anomer
FORC53_3606	COG3119	arylsulfatase activity
FORC53_3608	COG3119	arylsulfatase activity
FORC53_3609	COG0641	radical SAM
FORC53_3610	COG0714	Associated with various cellular activities
FORC53_3616	COG0583	DNA-binding transcription factor activity
FORC53_3617	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
FORC53_3619	COG0641	radical SAM
FORC53_3625	COG2814	Major facilitator Superfamily
FORC53_3636	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC53_3638	COG1132	(ABC) transporter
FORC53_3643	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC53_3643	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC53_3645	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FORC53_3654	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FORC53_3654	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC53_3654	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC53_3655	COG1105	Belongs to the carbohydrate kinase PfkB family
FORC53_3656	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC53_3656	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC53_3657	COG1609	Transcriptional regulator
FORC53_3662	COG0469	pyruvate kinase activity
FORC53_3663	COG0469	pyruvate kinase activity
FORC53_3664	COG2271	Major facilitator Superfamily
FORC53_3665	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC53_3666	COG4191	Histidine kinase
FORC53_3668	COG1979	alcohol dehydrogenase
FORC53_3669	COG2207	Transcriptional regulator
FORC53_3672	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FORC53_3673	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC53_3676	COG3437	response regulator, receiver
FORC53_3676	COG0784	Response regulator, receiver
FORC53_3677	COG0546	phosphoglycolate phosphatase activity
FORC53_3680	COG0513	Belongs to the DEAD box helicase family
FORC53_3683	COG3038	cytochrome b561
FORC53_3685	COG2116	formate transmembrane transporter activity
FORC53_3686	COG0583	DNA-binding transcription factor activity
FORC53_3688	COG3593	DNA synthesis involved in DNA repair
FORC53_3689	COG0737	Belongs to the 5'-nucleotidase family
FORC53_3690	COG0861	Integral membrane protein TerC family
FORC53_3696	COG2267	carboxylic ester hydrolase activity
FORC53_3697	COG2067	long-chain fatty acid transport protein
FORC53_3700	COG2050	protein possibly involved in aromatic compounds catabolism
FORC53_3702	COG4533	DNA binding
FORC53_3704	COG0366	Alpha amylase catalytic
FORC53_3705	COG0583	DNA-binding transcription factor activity
FORC53_3709	COG0484	heat shock protein binding
FORC53_3712	COG1716	ATPase activity
FORC53_3712	COG5001	Diguanylate cyclase
FORC53_3713	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FORC53_3715	COG4181	ATPase activity
FORC53_3716	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FORC53_3717	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC53_3717	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FORC53_3718	COG1984	allophanate hydrolase subunit 2
FORC53_3719	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FORC53_3720	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FORC53_3722	COG5001	Diguanylate cyclase
FORC53_3722	COG3447	MASE1 domain protein
FORC53_3722	COG5002	protein histidine kinase activity
FORC53_3724	COG0583	DNA-binding transcription factor activity
FORC53_3725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC53_3725	COG1042	CoA-binding domain protein
FORC53_3725	COG0045	succinate-CoA ligase (ADP-forming) activity
FORC53_3729	COG0023	Translation Initiation Factor
FORC53_3745	COG1280	lysine exporter protein (LysE YggA)
FORC53_3748	COG2801	Transposase and inactivated derivatives
FORC53_3750	COG3140	Belongs to the UPF0181 family
FORC53_3753	COG0745	RESPONSE REGULATOR receiver
FORC53_3755	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FORC53_3756	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FORC53_3759	COG3706	GGDEF domain
FORC53_3761	COG0745	RESPONSE REGULATOR receiver
FORC53_3763	COG1846	Transcriptional regulator
FORC53_3764	COG0697	spore germination
FORC53_3766	COG4149	molybdate abc transporter
FORC53_3767	COG0725	ABC transporter, periplasmic molybdate-binding protein
FORC53_3771	COG0189	ligase activity
FORC53_3771	COG4067	protein conserved in archaea
FORC53_3773	COG0840	transmembrane signaling receptor activity
FORC53_3774	COG0602	queuosine metabolic process
FORC53_3775	COG1328	CTP reductase activity
FORC53_3786	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC53_3787	COG3118	belongs to the thioredoxin family
FORC53_3788	COG0477	Major facilitator Superfamily
FORC53_3790	COG0534	Mate efflux family protein
FORC53_3793	COG0840	transmembrane signaling receptor activity
FORC53_3794	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC53_3797	COG0848	biopolymer transport protein
FORC53_3798	COG0811	peptide transport
FORC53_3799	COG0811	peptide transport
FORC53_3805	COG2146	nitrite reductase [NAD(P)H] activity
FORC53_3806	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC53_3807	COG0840	transmembrane signaling receptor activity
FORC53_3812	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC53_3814	COG2203	Gaf domain
FORC53_3814	COG4251	negative regulation of phosphorylation
FORC53_3814	COG3706	GGDEF domain
FORC53_3814	COG5001	Diguanylate cyclase
FORC53_3816	COG0010	Belongs to the arginase family
FORC53_3817	COG0513	Belongs to the DEAD box helicase family
FORC53_3819	COG0523	cobalamin synthesis protein
FORC53_3821	COG2199	diguanylate cyclase activity
FORC53_3824	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC53_3824	COG2146	nitrite reductase [NAD(P)H] activity
FORC53_3825	COG1116	anion transmembrane transporter activity
FORC53_3826	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC53_3827	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC53_3827	COG1116	anion transmembrane transporter activity
FORC53_3828	COG3707	response regulator
FORC53_3831	COG1648	precorrin-2 dehydrogenase activity
FORC53_3831	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC53_3832	COG0243	molybdopterin cofactor binding
FORC53_3833	COG0456	acetyltransferase
FORC53_3834	COG0366	Alpha amylase catalytic
FORC53_3839	COG2271	Major facilitator Superfamily
FORC53_3840	COG0584	glycerophosphoryl diester phosphodiesterase
FORC53_3841	COG0312	modulator of DNA gyrase
FORC53_3842	COG0312	modulator of DNA gyrase
FORC53_3844	COG3069	C4-dicarboxylate transmembrane transporter activity
FORC53_3845	COG1704	LemA family
FORC53_3846	COG0501	Belongs to the peptidase M48B family
FORC53_3850	COG5444	nuclease activity
FORC53_3851	COG3209	COG3209 Rhs family protein
FORC53_3853	COG3335	DDE superfamily endonuclease
FORC53_3855	COG3209	COG3209 Rhs family protein
FORC53_3858	COG3501	Rhs element vgr protein
FORC53_3869	COG0631	protein serine/threonine phosphatase activity
FORC53_3876	COG2815	serine threonine protein kinase
FORC53_3876	COG0515	serine threonine protein kinase
FORC53_3880	COG3530	Putative quorum-sensing-regulated virulence factor
FORC53_3886	COG3186	Phenylalanine-4-hydroxylase
FORC53_3887	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC53_3893	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FORC53_3895	COG4191	Histidine kinase
FORC53_3895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC53_3896	COG0784	Response regulator, receiver
FORC53_3896	COG3437	response regulator, receiver
FORC53_3899	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FORC53_3908	COG1073	alpha beta
FORC53_3908	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FORC53_3908	COG3064	Membrane
FORC53_3909	COG2994	toxin metabolic process
FORC53_3914	COG1028	Short-chain dehydrogenase reductase Sdr
FORC53_3916	COG1024	Enoyl-CoA hydratase
FORC53_3917	COG1024	Enoyl-CoA hydratase
FORC53_3918	COG1960	acyl-CoA dehydrogenase activity
FORC53_3920	COG0183	Belongs to the thiolase family
FORC53_3922	COG1960	acyl-CoA dehydrogenase activity
FORC53_3923	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FORC53_3926	COG0450	alkyl hydroperoxide reductase
FORC53_3928	COG1278	Cold shock
FORC53_3931	COG1309	transcriptional regulator
FORC53_3932	COG2130	NADP-dependent
FORC53_3936	COG2197	response regulator
FORC53_3937	COG3851	Histidine kinase
FORC53_3938	COG2271	Major facilitator Superfamily
FORC53_3939	COG1482	cell wall glycoprotein biosynthetic process
FORC53_3940	COG2203	Gaf domain
FORC53_3940	COG2199	diguanylate cyclase activity
FORC53_3942	COG3036	rescue of stalled ribosome
FORC53_3943	COG1278	Cold shock
FORC53_3950	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC53_3951	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC53_3953	COG0840	transmembrane signaling receptor activity
FORC53_3957	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC53_3959	COG4989	oxidoreductase activity
FORC53_3966	COG1914	H( )-stimulated, divalent metal cation uptake system
FORC53_3968	COG0303	'Molybdopterin
FORC53_3969	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC53_3970	COG2897	thiosulfate sulfurtransferase activity
FORC53_3978	COG0840	transmembrane signaling receptor activity
FORC53_3979	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC53_3980	COG2885	chlorophyll binding
FORC53_3981	COG0109	protoheme IX farnesyltransferase activity
FORC53_3982	COG1612	heme a metabolic process
FORC53_3987	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FORC53_3988	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FORC53_3989	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FORC53_3990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC53_3992	COG1280	lysine exporter protein (LysE YggA)
FORC53_3997	COG1846	Transcriptional regulator
FORC53_3998	COG1764	response to oxidative stress
FORC53_4000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC53_4003	COG0697	spore germination
FORC53_4006	COG2814	Major facilitator Superfamily
FORC53_4007	COG0583	DNA-binding transcription factor activity
FORC53_4008	COG2203	Gaf domain
FORC53_4008	COG3706	GGDEF domain
FORC53_4008	COG4251	negative regulation of phosphorylation
FORC53_4008	COG5001	Diguanylate cyclase
FORC53_4009	COG0251	oxidation-reduction process
FORC53_4011	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FORC53_4013	COG4145	pantothenate transmembrane transporter activity
FORC53_4015	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FORC53_4017	COG1737	Transcriptional regulator
FORC53_4017	COG0837	glucose binding
FORC53_4019	COG1131	(ABC) transporter
FORC53_4020	COG0842	Transport permease protein
FORC53_4025	COG1846	Transcriptional regulator
FORC53_4026	COG2514	catechol 2,3-dioxygenase activity
FORC53_4028	COG0513	Belongs to the DEAD box helicase family
FORC53_4034	COG3568	Endonuclease Exonuclease Phosphatase
FORC53_4037	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC53_4080	COG2356	endonuclease I
FORC53_4090	COG0330	HflC and HflK could
FORC53_4094	COG3457	Alanine racemase
FORC53_4099	COG2801	Transposase and inactivated derivatives
FORC53_4100	COG3604	Transcriptional regulator
FORC53_4102	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FORC53_4104	COG4208	sulfate ABC transporter
FORC53_4108	COG0628	permease
FORC53_4114	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC53_4116	COG1566	PFAM secretion protein HlyD family protein
FORC53_4129	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FORC53_4129	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FORC53_4133	COG2197	response regulator
FORC53_4134	COG3850	Histidine kinase
FORC53_4135	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC53_4139	COG3005	denitrification pathway
FORC53_4140	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FORC53_4141	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FORC53_4142	COG1737	Transcriptional regulator
FORC53_4143	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC53_4144	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FORC53_4145	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC53_4146	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FORC53_4148	COG1940	carbohydrate kinase activity
FORC53_4149	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC53_4153	COG0183	Belongs to the thiolase family
FORC53_4156	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC53_4157	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC53_4166	COG1879	ABC-type sugar transport system periplasmic component
FORC53_4168	COG2827	Endonuclease containing a URI domain
FORC53_4172	COG0534	Mate efflux family protein
FORC53_4173	COG5002	protein histidine kinase activity
FORC53_4173	COG2205	protein histidine kinase activity
FORC53_4173	COG0784	Response regulator, receiver
FORC53_4178	COG0583	DNA-binding transcription factor activity
FORC53_4183	COG1522	sequence-specific DNA binding
FORC53_4185	COG0531	amino acid
FORC53_4186	COG0121	glutamine amidotransferase
FORC53_4189	COG2205	protein histidine kinase activity
FORC53_4190	COG0745	RESPONSE REGULATOR receiver
FORC53_4195	COG2239	Acts as a magnesium transporter
FORC53_4197	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FORC53_4198	COG0402	S-adenosylhomocysteine deaminase activity
FORC53_4199	COG1067	ATP-dependent peptidase activity
FORC53_4201	COG4172	Belongs to the ABC transporter superfamily
FORC53_4202	COG1505	serine-type exopeptidase activity
FORC53_4203	COG0583	DNA-binding transcription factor activity
FORC53_4204	COG1620	l-lactate permease
FORC53_4206	COG1139	Iron-sulfur cluster binding protein
FORC53_4211	COG2814	Major facilitator Superfamily
FORC53_4216	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC53_4219	COG3015	lipoprotein NlpE involved in copper resistance
FORC53_4220	COG1126	abc transporter atp-binding protein
FORC53_4221	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC53_4222	COG4215	(ABC) transporter
FORC53_4223	COG4160	amino acid transport
FORC53_4226	COG5001	Diguanylate cyclase
FORC53_4226	COG5002	protein histidine kinase activity
FORC53_4227	COG2755	lipolytic protein G-D-S-L family
FORC53_4229	COG0840	transmembrane signaling receptor activity
FORC53_4230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC53_4234	COG2977	Belongs to the P-Pant transferase superfamily
FORC53_4237	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC53_4238	COG1028	Short-chain dehydrogenase reductase Sdr
FORC53_4239	COG1169	isochorismate synthase
FORC53_4240	COG1021	2,3-dihydroxybenzoate-AMP ligase
FORC53_4245	COG1021	2,3-dihydroxybenzoate-AMP ligase
FORC53_4247	COG4607	ABC-type enterochelin transport system periplasmic component
FORC53_4248	COG1629	transport
FORC53_4248	COG4774	siderophore transport
FORC53_4252	COG4067	protein conserved in archaea
FORC53_4252	COG0189	ligase activity
FORC53_4258	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC53_4261	COG0814	amino acid
FORC53_4262	COG0488	(ABC) transporter
FORC53_4265	COG1609	Transcriptional regulator
FORC53_4266	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC53_4271	COG1253	flavin adenine dinucleotide binding
FORC53_4273	COG1012	belongs to the aldehyde dehydrogenase family
FORC53_4274	COG3284	Transcriptional regulator
FORC53_4276	COG1879	ABC-type sugar transport system periplasmic component
FORC53_4277	COG0625	glutathione transferase activity
FORC53_4279	COG0384	phenazine biosynthesis protein PhzF
FORC53_4280	COG2197	response regulator
FORC53_4282	COG0673	inositol 2-dehydrogenase activity
FORC53_4287	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FORC53_4289	COG0583	DNA-binding transcription factor activity
FORC53_4290	COG2194	sulfuric ester hydrolase activity
FORC53_4294	COG0798	PFAM Bile acid sodium symporter
FORC53_4295	COG0640	Transcriptional regulator
FORC53_4298	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC53_4299	COG0700	Nucleoside recognition
FORC53_4300	COG3366	ferrous iron transmembrane transporter activity
FORC53_4302	COG0366	Alpha amylase catalytic
FORC53_4304	COG0800	Aldolase
FORC53_4305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC53_4306	COG0697	spore germination
FORC53_4314	COG1917	Cupin 2, conserved barrel domain protein
FORC53_4316	COG1028	Short-chain dehydrogenase reductase Sdr
FORC53_4322	COG3153	acetyltransferase
FORC53_4322	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC53_4326	COG0668	transmembrane transport
FORC53_4333	COG0494	nUDIX hydrolase
FORC53_4334	COG1881	PFAM PEBP family protein
FORC53_4335	COG2207	Transcriptional regulator
FORC53_4336	COG3046	protein related to deoxyribodipyrimidine photolyase
FORC53_4340	COG0745	RESPONSE REGULATOR receiver
FORC53_4341	COG2205	protein histidine kinase activity
FORC53_4345	COG0454	-acetyltransferase
FORC53_4346	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC53_4351	COG1858	cytochrome C peroxidase
FORC53_4355	COG2814	Major facilitator Superfamily
FORC53_4359	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FORC53_4361	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC53_4364	COG0583	DNA-binding transcription factor activity
FORC53_4368	COG0513	Belongs to the DEAD box helicase family
FORC53_4375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC53_4377	COG1357	PFAM Pentapeptide repeats (8 copies)
FORC53_4381	COG3437	response regulator, receiver
FORC53_4383	COG0579	oxidoreductase
FORC53_4389	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FORC53_4392	COG2205	protein histidine kinase activity
FORC53_4396	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FORC53_4399	COG3706	GGDEF domain
FORC53_4403	COG2176	DNA-directed DNA polymerase activity
FORC53_4404	COG1136	(ABC) transporter
FORC53_4404	COG0577	efflux transmembrane transporter activity
FORC53_4405	COG0577	efflux transmembrane transporter activity
FORC53_4405	COG1136	(ABC) transporter
FORC53_4412	COG1120	ATPase activity
FORC53_4413	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC53_4419	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC53_4420	COG3716	PTS system mannose fructose sorbose family IID component
FORC53_4422	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC53_4423	COG2222	sugar isomerase
FORC53_4425	COG1349	DNA-binding transcription factor activity
FORC53_4427	COG1349	DNA-binding transcription factor activity
FORC53_4428	COG0697	spore germination
FORC53_4432	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FORC53_4437	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC53_4438	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC53_4442	COG0840	transmembrane signaling receptor activity
FORC53_4445	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC53_4448	COG0583	DNA-binding transcription factor activity
FORC53_4449	COG1486	melibiose metabolic process
FORC53_4451	COG1522	sequence-specific DNA binding
FORC53_4454	COG2258	MOSC domain
FORC53_4459	COG1757	Na H antiporter
FORC53_4460	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FORC53_4461	COG0513	Belongs to the DEAD box helicase family
FORC53_4463	COG2186	Transcriptional regulator
FORC53_4465	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC53_4467	COG0246	Mannitol dehydrogenase
FORC53_4468	COG1904	glucuronate isomerase
FORC53_4469	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC53_4470	COG0800	Aldolase
FORC53_4473	COG1028	Short-chain dehydrogenase reductase Sdr
FORC53_4474	COG2999	glutathione oxidoreductase activity
FORC53_4475	COG1902	pentaerythritol trinitrate reductase activity
FORC53_4482	COG0561	phosphatase activity
FORC53_4483	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FORC53_4484	COG3623	hexulose-6-phosphate isomerase
FORC53_4487	COG1132	(ABC) transporter
FORC53_4488	COG5492	domain, Protein
FORC53_4489	COG5426	von Willebrand factor, type A
FORC53_4491	COG1028	Short-chain dehydrogenase reductase Sdr
FORC53_4493	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC53_4494	COG0659	secondary active sulfate transmembrane transporter activity
FORC53_4499	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC53_4500	COG0601	transmembrane transport
FORC53_4501	COG0747	negative chemotaxis
FORC53_4503	COG3119	arylsulfatase activity
FORC53_4504	COG0641	radical SAM
FORC53_4505	COG3119	arylsulfatase activity
FORC53_4506	COG3119	arylsulfatase activity
FORC53_4507	COG5492	domain, Protein
FORC53_4512	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC53_4520	COG2204	response regulator
FORC53_4529	COG0110	maltose O-acetyltransferase activity
FORC53_4532	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC53_4532	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC53_4533	COG1737	Transcriptional regulator
FORC53_4535	COG1263	PTS System
FORC53_4535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC53_4537	COG2199	diguanylate cyclase activity
FORC53_4537	COG2200	EAL domain
FORC53_4537	COG2203	Gaf domain
FORC53_4538	COG0406	alpha-ribazole phosphatase activity
FORC53_4540	COG0583	DNA-binding transcription factor activity
FORC53_4541	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FORC53_4547	COG3706	GGDEF domain
FORC53_4547	COG0745	RESPONSE REGULATOR receiver
FORC53_4549	COG0840	transmembrane signaling receptor activity
FORC53_4550	COG2201	protein-glutamate methylesterase activity
FORC53_4551	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FORC53_4552	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC53_4553	COG0840	transmembrane signaling receptor activity
FORC53_4554	COG0835	chemotaxis
FORC53_4557	COG0745	RESPONSE REGULATOR receiver
FORC53_4559	COG1444	tRNA N-acetyltransferase activity
FORC53_4585	COG2916	Histone family protein nucleoid-structuring protein H-NS
FORC53_4595	COG1051	belongs to the nudix hydrolase family
FORC53_4597	COG0671	phosphoesterase, PA-phosphatase related
FORC53_4598	COG0671	phosphoesterase, PA-phosphatase related
FORC53_4605	COG0629	single-stranded DNA binding
FORC53_4642	COG0148	phosphopyruvate hydratase activity
FORC53_4679	COG4682	membrane
FORC53_4715	COG1129	ABC transporter
FORC53_4766	COG1328	CTP reductase activity
FORC53_4808	COG0671	phosphoesterase, PA-phosphatase related
FORC53_4821	COG0194	GDP metabolic process
FORC53_4852	COG1475	DNA binding
FORC53_4855	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FORC53_4876	COG1253	flavin adenine dinucleotide binding
FORC53_4887	COG0776	regulation of translation
FORC53_4888	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC53_4889	COG1192	Involved in chromosome partitioning
FORC53_4895	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FORC53_4936	COG1160	GTP binding
FORC53_4945	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FORC53_4949	COG0628	permease
FORC53_4955	COG0629	single-stranded DNA binding
FORC53_4977	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC53_4996	COG0328	RNA-DNA hybrid ribonuclease activity
FORC53_4996	COG3341	Caulimovirus viroplasmin
FORC53_5015	COG2137	regulation of response to DNA damage stimulus
FORC53_5023	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FORC53_5025	COG1358	cellular component organization or biogenesis
FORC53_5031	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC53_5032	COG2194	sulfuric ester hydrolase activity
FORC53_5034	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FORC53_5047	COG0105	UTP biosynthetic process
FORC53_5078	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC53_5078	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC53_5086	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FORC53_5100	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FORC53_5106	COG0602	queuosine metabolic process
FORC53_5107	COG0776	regulation of translation
FORC53_5115	COG2304	oxidoreductase activity
FORC53_5116	COG1570	exodeoxyribonuclease VII activity
FORC53_5119	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FORC53_5132	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FORC53_5141	COG0776	regulation of translation
FORC53_5151	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC53_5156	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FORC53_5158	COG0822	iron-sulfur transferase activity
FORC53_5162	COG1435	thymidine kinase activity
FORC53_5167	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FORC53_5171	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FORC53_5172	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FORC53_5180	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FORC53_5185	COG3038	cytochrome b561
FORC53_5190	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC53_5191	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC53_5199	COG1358	cellular component organization or biogenesis
FORC53_5202	COG2310	stress, protein
FORC53_5205	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FORC53_5211	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FORC53_5214	COG3706	GGDEF domain
FORC53_5279	COG0210	DNA helicase
FORC53_5295	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC53_5301	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FORC53_5318	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FORC53_5326	COG0740	serine-type endopeptidase activity
FORC53_5331	COG0653	protein targeting
FORC53_5333	COG1078	dGTPase activity
FORC53_5339	COG0497	DNA recombination
FORC53_5346	COG2974	May be involved in recombination
FORC53_5360	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC53_5367	COG0514	ATP-dependent DNA helicase (RecQ)
FORC53_5369	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC53_5371	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FORC53_5375	COG0750	zinc metalloprotease
FORC53_5377	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC53_5378	COG0305	Participates in initiation and elongation during chromosome replication
FORC53_5379	COG0587	DNA-directed DNA polymerase activity
FORC53_5382	COG0316	Belongs to the HesB IscA family
FORC53_5383	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FORC53_5387	COG2200	EAL domain
FORC53_5390	COG0210	DNA helicase
FORC53_5392	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FORC53_5400	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC53_5400	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC53_5401	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FORC53_5404	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC53_5413	COG2925	Exonuclease
FORC53_5425	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC53_5428	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC53_5488	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC53_5488	COG0678	peroxiredoxin activity
FORC53_5539	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FORC53_5556	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC53_5559	COG3550	peptidyl-serine autophosphorylation
FORC53_5584	COG2137	regulation of response to DNA damage stimulus
FORC53_5601	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FORC53_5614	COG1199	ATP-dependent helicase activity
FORC53_5622	COG3093	addiction module antidote protein HigA
FORC53_5646	COG0494	nUDIX hydrolase