locus-tag	class	description
FORC54_0002	COG0592	DNA-directed DNA polymerase activity
FORC54_0004	COG0187	DNA topoisomerase II activity
FORC54_0005	COG0071	Belongs to the small heat shock protein (HSP20) family
FORC54_0007	COG3977	Valine--pyruvate aminotransferase
FORC54_0010	COG0751	glycine-tRNA ligase activity
FORC54_0012	COG2119	membrane
FORC54_0016	COG0604	alcohol dehydrogenase
FORC54_0017	COG0183	Belongs to the thiolase family
FORC54_0019	COG1739	Uncharacterized protein family UPF0029
FORC54_0020	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC54_0021	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
FORC54_0022	COG3335	DDE superfamily endonuclease
FORC54_0024	COG2132	Multicopper oxidase
FORC54_0027	COG0352	thiamine-phosphate diphosphorylase activity
FORC54_0028	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC54_0032	COG0006	proline dipeptidase activity
FORC54_0032	COG0006	proline dipeptidase activity
FORC54_0040	COG0210	DNA helicase
FORC54_0041	COG1280	lysine exporter protein (LysE YggA)
FORC54_0043	COG2962	Rard protein
FORC54_0044	COG0514	ATP-dependent DNA helicase (RecQ)
FORC54_0046	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FORC54_0049	COG3118	belongs to the thioredoxin family
FORC54_0050	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FORC54_0055	COG3335	DDE superfamily endonuclease
FORC54_0059	COG1322	Protein conserved in bacteria
FORC54_0061	COG3165	ubiquinone biosynthetic process from chorismate
FORC54_0063	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORC54_0065	COG0805	protein transport
FORC54_0066	COG0084	hydrolase, TatD family'
FORC54_0068	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC54_0068	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC54_0069	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FORC54_0074	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC54_0075	COG5001	Diguanylate cyclase
FORC54_0075	COG3300	MHYT domain
FORC54_0076	COG2204	response regulator
FORC54_0077	COG3852	Histidine kinase
FORC54_0079	COG0174	glutamine synthetase
FORC54_0083	COG1295	ribonuclease BN
FORC54_0085	COG0456	acetyltransferase
FORC54_0089	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FORC54_0091	COG3031	protein transport across the cell outer membrane
FORC54_0093	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC54_0094	COG1459	type II secretion system
FORC54_0095	COG2165	general secretion pathway protein
FORC54_0096	COG2165	general secretion pathway protein
FORC54_0097	COG2165	general secretion pathway protein
FORC54_0098	COG4795	General secretion pathway protein
FORC54_0099	COG3156	type II secretion system protein K
FORC54_0100	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FORC54_0101	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FORC54_0103	COG1218	3'(2'),5'-bisphosphate nucleotidase
FORC54_0104	COG0494	nUDIX hydrolase
FORC54_0107	COG0596	Alpha beta hydrolase
FORC54_0109	COG2183	response to ionizing radiation
FORC54_0112	COG4221	oxidoreductase activity
FORC54_0116	COG1129	ABC transporter
FORC54_0117	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC54_0118	COG1472	Belongs to the glycosyl hydrolase 3 family
FORC54_0119	COG0745	RESPONSE REGULATOR receiver
FORC54_0121	COG2233	PERMEase
FORC54_0122	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FORC54_0123	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC54_0124	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC54_0129	COG0848	biopolymer transport protein
FORC54_0130	COG0811	peptide transport
FORC54_0131	COG0811	peptide transport
FORC54_0133	COG4206	TonB-dependent receptor
FORC54_0135	COG4174	ABC transporter (Permease)
FORC54_0136	COG4239	(ABC) transporter, permease
FORC54_0137	COG0747	negative chemotaxis
FORC54_0138	COG0444	Belongs to the ABC transporter superfamily
FORC54_0139	COG4608	Belongs to the ABC transporter superfamily
FORC54_0145	COG1561	YicC-like family, N-terminal region
FORC54_0148	COG1560	Kdo2-lipid A biosynthetic process
FORC54_0152	COG2003	Belongs to the UPF0758 family
FORC54_0159	COG0859	PFAM glycosyl transferase family 9
FORC54_0160	COG0463	Glycosyl transferase, family 2
FORC54_0161	COG0859	PFAM glycosyl transferase family 9
FORC54_0162	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC54_0163	COG3642	lipopolysaccharide core region biosynthetic process
FORC54_0165	COG3083	sulfuric ester hydrolase activity
FORC54_0168	COG1086	Polysaccharide biosynthesis protein
FORC54_0170	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FORC54_0173	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FORC54_0174	COG0107	imidazoleglycerol-phosphate synthase activity
FORC54_0177	COG2089	acid synthase
FORC54_0179	COG1519	Transferase
FORC54_0181	COG0859	PFAM glycosyl transferase family 9
FORC54_0184	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC54_0191	COG1596	polysaccharide export
FORC54_0196	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FORC54_0200	COG0110	maltose O-acetyltransferase activity
FORC54_0201	COG0110	maltose O-acetyltransferase activity
FORC54_0205	COG0438	transferase activity, transferring glycosyl groups
FORC54_0208	COG1482	cell wall glycoprotein biosynthetic process
FORC54_0210	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC54_0211	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FORC54_0215	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FORC54_0217	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FORC54_0237	COG0201	protein transport
FORC54_0240	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FORC54_0245	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC54_0246	COG3061	Opacity-associated protein A
FORC54_0246	COG3266	domain, Protein
FORC54_0248	COG2153	protein acetylation
FORC54_0250	COG0737	Belongs to the 5'-nucleotidase family
FORC54_0251	COG1648	precorrin-2 dehydrogenase activity
FORC54_0251	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC54_0253	COG2895	sulfate adenylyltransferase (ATP) activity
FORC54_0254	COG0471	metal ion transport
FORC54_0254	COG3273	potassium ion transport
FORC54_0259	COG0577	efflux transmembrane transporter activity
FORC54_0259	COG1136	(ABC) transporter
FORC54_0262	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FORC54_0265	COG0729	surface antigen
FORC54_0266	COG2911	Protein conserved in bacteria
FORC54_0267	COG2105	PFAM AIG2 family protein
FORC54_0271	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC54_0272	COG0163	prenyltransferase activity
FORC54_0273	COG4143	(ABC) transporter
FORC54_0274	COG1178	ABC-type Fe3 transport system permease component
FORC54_0276	COG3028	Belongs to the UPF0307 family
FORC54_0277	COG0312	modulator of DNA gyrase
FORC54_0278	COG2239	Acts as a magnesium transporter
FORC54_0279	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC54_0280	COG1660	Displays ATPase and GTPase activities
FORC54_0281	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC54_0282	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC54_0284	COG1137	ATPase activity
FORC54_0285	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FORC54_0287	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FORC54_0288	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FORC54_0288	COG0517	IMP dehydrogenase activity
FORC54_0290	COG1127	ABC transporter
FORC54_0291	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FORC54_0292	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FORC54_0293	COG2854	intermembrane phospholipid transfer
FORC54_0295	COG5007	Belongs to the BolA IbaG family
FORC54_0297	COG0204	Acyl-transferase
FORC54_0298	COG0589	response to stress
FORC54_0302	COG0039	L-malate dehydrogenase activity
FORC54_0303	COG0142	geranyltranstransferase activity
FORC54_0304	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FORC54_0307	COG2966	Psort location CytoplasmicMembrane, score
FORC54_0308	COG3610	response to peptide
FORC54_0318	COG0066	3-isopropylmalate dehydratase activity
FORC54_0320	COG0473	3-isopropylmalate dehydrogenase activity
FORC54_0326	COG1022	Amp-dependent synthetase and ligase
FORC54_0327	COG0028	Belongs to the TPP enzyme family
FORC54_0328	COG0440	acetolactate synthase activity
FORC54_0329	COG3706	GGDEF domain
FORC54_0331	COG0469	pyruvate kinase activity
FORC54_0332	COG1349	DNA-binding transcription factor activity
FORC54_0333	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FORC54_0334	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FORC54_0337	COG3550	peptidyl-serine autophosphorylation
FORC54_0341	COG2207	Transcriptional regulator
FORC54_0344	COG3501	Rhs element vgr protein
FORC54_0355	COG1181	Belongs to the D-alanine--D-alanine ligase family
FORC54_0369	COG3547	Transposase (IS116 IS110 IS902 family)
FORC54_0370	COG2003	Belongs to the UPF0758 family
FORC54_0373	COG3339	Conserved Protein
FORC54_0380	COG3385	transposase activity
FORC54_0385	COG0582	viral genome integration into host DNA
FORC54_0386	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORC54_0388	COG1610	YqeY-like protein
FORC54_0389	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FORC54_0392	COG0596	Alpha beta hydrolase
FORC54_0394	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FORC54_0395	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC54_0397	COG0617	tRNA 3'-terminal CCA addition
FORC54_0398	COG3267	Type II secretory pathway component ExeA
FORC54_0398	COG3409	Peptidoglycan-binding domain 1 protein
FORC54_0399	COG4991	sh3 domain protein
FORC54_0400	COG0306	phosphate transporter
FORC54_0401	COG1392	Phosphate transport regulator
FORC54_0402	COG3025	triphosphatase activity
FORC54_0403	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC54_0405	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FORC54_0407	COG1538	Outer membrane efflux protein
FORC54_0408	COG0494	nUDIX hydrolase
FORC54_0409	COG3151	Protein conserved in bacteria
FORC54_0411	COG3150	esterase
FORC54_0412	COG0187	DNA topoisomerase II activity
FORC54_0414	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC54_0415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC54_0416	COG3105	Protein conserved in bacteria
FORC54_0417	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FORC54_0420	COG0723	plastoquinol--plastocyanin reductase activity
FORC54_0421	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FORC54_0422	COG2857	Cytochrome c1
FORC54_0423	COG0625	glutathione transferase activity
FORC54_0424	COG2969	positive regulation of protein catabolic process
FORC54_0425	COG2823	Periplasmic or secreted lipoprotein
FORC54_0426	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FORC54_0428	COG3107	peptidoglycan biosynthetic process
FORC54_0429	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FORC54_0431	COG3116	cell division
FORC54_0432	COG0768	penicillin binding
FORC54_0434	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FORC54_0435	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORC54_0436	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FORC54_0437	COG0772	Belongs to the SEDS family
FORC54_0439	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC54_0440	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FORC54_0441	COG0849	cell division
FORC54_0442	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FORC54_0445	COG0653	protein targeting
FORC54_0446	COG0494	nUDIX hydrolase
FORC54_0448	COG0505	Belongs to the CarA family
FORC54_0452	COG0730	response to heat
FORC54_0453	COG0583	DNA-binding transcription factor activity
FORC54_0454	COG2860	membrane
FORC54_0457	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FORC54_0459	COG0493	'glutamate synthase
FORC54_0460	COG0069	glutamate synthase activity
FORC54_0460	COG0070	glutamate synthase
FORC54_0460	COG0067	glutamate synthase
FORC54_0462	COG0067	glutamate synthase
FORC54_0462	COG0069	glutamate synthase activity
FORC54_0462	COG0070	glutamate synthase
FORC54_0463	COG1242	4 iron, 4 sulfur cluster binding
FORC54_0464	COG5001	Diguanylate cyclase
FORC54_0464	COG2203	Gaf domain
FORC54_0464	COG3706	GGDEF domain
FORC54_0464	COG4251	negative regulation of phosphorylation
FORC54_0465	COG2198	Histidine kinase
FORC54_0465	COG5002	protein histidine kinase activity
FORC54_0465	COG0784	Response regulator, receiver
FORC54_0467	COG0745	RESPONSE REGULATOR receiver
FORC54_0473	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FORC54_0479	COG1115	amino acid carrier protein
FORC54_0480	COG3022	response to hydroperoxide
FORC54_0481	COG0513	Belongs to the DEAD box helicase family
FORC54_0484	COG0716	FMN binding
FORC54_0486	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC54_0487	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FORC54_0488	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FORC54_0489	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FORC54_0492	COG0667	Aldo Keto reductase
FORC54_0493	COG0667	Aldo Keto reductase
FORC54_0498	COG0730	response to heat
FORC54_0502	COG1283	sodium-dependent phosphate transmembrane transporter activity
FORC54_0503	COG0583	DNA-binding transcription factor activity
FORC54_0504	COG0640	Transcriptional regulator
FORC54_0506	COG0728	peptidoglycan biosynthetic process
FORC54_0507	COG0196	riboflavin kinase activity
FORC54_0508	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FORC54_0510	COG1047	Peptidyl-prolyl cis-trans
FORC54_0513	COG3275	phosphorelay sensor kinase activity
FORC54_0514	COG1966	Carbon starvation protein
FORC54_0518	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FORC54_0519	COG1472	Belongs to the glycosyl hydrolase 3 family
FORC54_0520	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC54_0521	COG1605	Chorismate mutase
FORC54_0521	COG0287	Prephenate dehydrogenase
FORC54_0522	COG0739	heme binding
FORC54_0524	COG0488	(ABC) transporter
FORC54_0527	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FORC54_0528	COG1605	Chorismate mutase
FORC54_0528	COG0077	Prephenate dehydratase
FORC54_0529	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC54_0530	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC54_0535	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC54_0538	COG0745	RESPONSE REGULATOR receiver
FORC54_0539	COG5002	protein histidine kinase activity
FORC54_0541	COG0248	Ppx GppA phosphatase
FORC54_0542	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FORC54_0544	COG0581	inorganic phosphate transmembrane transporter activity
FORC54_0546	COG0704	Plays a role in the regulation of phosphate uptake
FORC54_0549	COG0450	alkyl hydroperoxide reductase
FORC54_0550	COG0583	DNA-binding transcription factor activity
FORC54_0551	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FORC54_0553	COG0517	IMP dehydrogenase activity
FORC54_0555	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FORC54_0557	COG1862	Preprotein translocase
FORC54_0558	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC54_0559	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC54_0562	COG0483	inositol monophosphate 1-phosphatase activity
FORC54_0563	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FORC54_0566	COG0822	iron-sulfur transferase activity
FORC54_0569	COG0443	Heat shock 70 kDa protein
FORC54_0570	COG0633	Ferredoxin
FORC54_0571	COG2975	iron-sulfur cluster assembly
FORC54_0578	COG2976	Protein conserved in bacteria
FORC54_0579	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC54_0582	COG2203	Gaf domain
FORC54_0582	COG2199	diguanylate cyclase activity
FORC54_0584	COG1570	exodeoxyribonuclease VII activity
FORC54_0585	COG0517	IMP dehydrogenase activity
FORC54_0585	COG0516	GMP reductase activity
FORC54_0586	COG0519	Catalyzes the synthesis of GMP from XMP
FORC54_0586	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FORC54_0588	COG1584	GPR1 FUN34 yaaH family protein
FORC54_0589	COG1115	amino acid carrier protein
FORC54_0592	COG0583	DNA-binding transcription factor activity
FORC54_0596	COG0009	L-threonylcarbamoyladenylate synthase
FORC54_0616	COG2867	negative regulation of translational initiation
FORC54_0618	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC54_0619	COG0497	DNA recombination
FORC54_0620	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FORC54_0621	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FORC54_0625	COG3344	reverse transcriptase
FORC54_0637	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FORC54_0638	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FORC54_0639	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FORC54_0640	COG0583	DNA-binding transcription factor activity
FORC54_0641	COG0590	tRNA wobble adenosine to inosine editing
FORC54_0648	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC54_0649	COG2252	PERMEase
FORC54_0655	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FORC54_0656	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC54_0656	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC54_0661	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FORC54_0662	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FORC54_0663	COG3344	reverse transcriptase
FORC54_0665	COG0142	geranyltranstransferase activity
FORC54_0668	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FORC54_0672	COG0583	DNA-binding transcription factor activity
FORC54_0674	COG2363	Small membrane protein
FORC54_0677	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC54_0678	COG1611	Belongs to the LOG family
FORC54_0679	COG3706	GGDEF domain
FORC54_0681	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FORC54_0681	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FORC54_0683	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FORC54_0684	COG1464	Belongs to the NlpA lipoprotein family
FORC54_0685	COG2011	ABC-type metal ion transport system permease component
FORC54_0686	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FORC54_0687	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC54_0689	COG1263	PTS System
FORC54_0689	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC54_0690	COG0366	Alpha amylase catalytic
FORC54_0701	COG0321	lipoyl(octanoyl) transferase activity
FORC54_0703	COG1686	Belongs to the peptidase S11 family
FORC54_0704	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FORC54_0705	COG0772	Belongs to the SEDS family
FORC54_0706	COG0768	penicillin binding
FORC54_0708	COG0799	negative regulation of ribosome biogenesis
FORC54_0709	COG1466	dna polymerase III delta subunit
FORC54_0710	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FORC54_0711	COG0495	leucyl-tRNA aminoacylation
FORC54_0712	COG2888	peptidyl-tyrosine sulfation
FORC54_0714	COG4535	Mg2 and Co2 transporter CorC
FORC54_0715	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FORC54_0716	COG1702	phosphate starvation-inducible protein PhoH
FORC54_0717	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC54_0718	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC54_0719	COG3344	reverse transcriptase
FORC54_0728	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC54_0729	COG3094	Invasion gene expression up-regulator, SirB
FORC54_0730	COG2912	Transglutaminase-like superfamily
FORC54_0734	COG1187	pseudouridine synthase activity
FORC54_0735	COG2840	Smr protein MutS2
FORC54_0737	COG3735	TraB family
FORC54_0740	COG2217	Heavy metal translocating P-type atpase
FORC54_0740	COG2608	mercury ion transmembrane transporter activity
FORC54_0751	COG0784	Response regulator, receiver
FORC54_0751	COG0835	chemotaxis
FORC54_0752	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC54_0753	COG1815	bacterial-type flagellum-dependent cell motility
FORC54_0754	COG1558	bacterial-type flagellum-dependent cell motility
FORC54_0755	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FORC54_0756	COG1749	Flagellar hook protein flgE
FORC54_0757	COG4787	bacterial-type flagellum-dependent cell motility
FORC54_0758	COG4786	Flagellar basal body rod
FORC54_0761	COG3951	Flagellar rod assembly protein muramidase FlgJ
FORC54_0761	COG1705	Flagellar rod assembly protein muramidase FlgJ
FORC54_0763	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC54_0764	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC54_0766	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC54_0767	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC54_0768	COG2190	(PTS) system
FORC54_0769	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FORC54_0770	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC54_0771	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC54_0772	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FORC54_0778	COG0330	HflC and HflK could
FORC54_0779	COG3118	belongs to the thioredoxin family
FORC54_0780	COG0300	oxidoreductase activity
FORC54_0781	COG1090	epimerase
FORC54_0786	COG0622	Phosphoesterase
FORC54_0790	COG3710	Transcriptional regulator
FORC54_0791	COG0326	Molecular chaperone. Has ATPase activity
FORC54_0793	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FORC54_0795	COG3104	oligopeptide transport
FORC54_0797	COG0367	asparagine synthase
FORC54_0798	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC54_0798	COG4651	solute:proton antiporter activity
FORC54_0799	COG1846	Transcriptional regulator
FORC54_0799	COG1940	carbohydrate kinase activity
FORC54_0800	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC54_0801	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC54_0801	COG1263	PTS System
FORC54_0802	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC54_0805	COG0716	FMN binding
FORC54_0807	COG0596	Alpha beta hydrolase
FORC54_0808	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FORC54_0809	COG0033	Phosphoglucomutase
FORC54_0810	COG2964	Protein conserved in bacteria
FORC54_0811	COG0251	oxidation-reduction process
FORC54_0813	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC54_0815	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FORC54_0817	COG2009	succinate dehydrogenase
FORC54_0818	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FORC54_0819	COG1053	succinate dehydrogenase
FORC54_0821	COG0567	Dehydrogenase, E1 component
FORC54_0822	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC54_0825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC54_0827	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FORC54_0829	COG1918	ferrous iron import across plasma membrane
FORC54_0830	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FORC54_0834	COG3102	Protein conserved in bacteria
FORC54_0835	COG0788	formyltetrahydrofolate deformylase activity
FORC54_0837	COG1199	ATP-dependent helicase activity
FORC54_0838	COG1214	PFAM Peptidase M22, glycoprotease
FORC54_0841	COG0596	Alpha beta hydrolase
FORC54_0842	COG0318	PFAM AMP-dependent synthetase and ligase
FORC54_0843	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FORC54_0845	COG2894	cell division
FORC54_0848	COG2951	lytic endotransglycosylase activity
FORC54_0850	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC54_0854	COG5002	protein histidine kinase activity
FORC54_0856	COG1028	Short-chain dehydrogenase reductase Sdr
FORC54_0858	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC54_0863	COG2986	histidine ammonia-lyase
FORC54_0864	COG1216	Glycosyl transferase, family 2
FORC54_0868	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC54_0869	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC54_0878	COG0745	RESPONSE REGULATOR receiver
FORC54_0883	COG3842	ATPase activity
FORC54_0885	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FORC54_0886	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC54_0887	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FORC54_0889	COG2204	response regulator
FORC54_0890	COG4191	Histidine kinase
FORC54_0894	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FORC54_0895	COG0776	regulation of translation
FORC54_0896	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC54_0897	COG1555	photosystem II stabilization
FORC54_0901	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FORC54_0902	COG0436	Aminotransferase
FORC54_0903	COG1169	isochorismate synthase
FORC54_0905	COG0596	Alpha beta hydrolase
FORC54_0906	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FORC54_0907	COG1441	menaquinone biosynthetic process
FORC54_0908	COG0318	PFAM AMP-dependent synthetase and ligase
FORC54_0916	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC54_0919	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC54_0920	COG1522	sequence-specific DNA binding
FORC54_0922	COG1946	Acyl-CoA thioesterase
FORC54_0923	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FORC54_0929	COG0330	HflC and HflK could
FORC54_0938	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC54_0941	COG3139	Protein of unknown function (DUF1315)
FORC54_0942	COG0252	asparaginase activity
FORC54_0943	COG0616	signal peptide processing
FORC54_0944	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC54_0944	COG1902	pentaerythritol trinitrate reductase activity
FORC54_0945	COG0778	Nitroreductase
FORC54_0946	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC54_0947	COG0123	including yeast histone deacetylase and acetoin utilization protein
FORC54_0949	COG0745	RESPONSE REGULATOR receiver
FORC54_0949	COG3706	GGDEF domain
FORC54_0950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC54_0951	COG2731	YhcH YjgK YiaL family protein
FORC54_0952	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC54_0953	COG0569	domain protein
FORC54_0954	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FORC54_0954	COG0784	Response regulator, receiver
FORC54_0958	COG3083	sulfuric ester hydrolase activity
FORC54_0959	COG3082	Protein of unknown function (DUF1414)
FORC54_0960	COG3081	Nucleoid-associated protein
FORC54_0963	COG1757	Na H antiporter
FORC54_0964	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC54_0966	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC54_0967	COG2095	MarC family integral membrane protein
FORC54_0968	COG1454	alcohol dehydrogenase
FORC54_0968	COG1012	belongs to the aldehyde dehydrogenase family
FORC54_0969	COG1028	Short-chain dehydrogenase reductase Sdr
FORC54_0972	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FORC54_0974	COG2056	Na+-H+ antiporter family
FORC54_0975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC54_0976	COG2885	chlorophyll binding
FORC54_0978	COG0346	lactoylglutathione lyase activity
FORC54_0979	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FORC54_0981	COG4659	FMN binding
FORC54_0984	COG4656	Part of a membrane complex involved in electron transport
FORC54_0991	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FORC54_0993	COG0521	Mo-molybdopterin cofactor biosynthetic process
FORC54_0994	COG0315	cyclic pyranopterin monophosphate synthase activity
FORC54_0995	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FORC54_0996	COG0314	molybdopterin synthase activity
FORC54_0999	COG0601	transmembrane transport
FORC54_1000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC54_1001	COG0444	Belongs to the ABC transporter superfamily
FORC54_1003	COG0435	Glutathione S-transferase
FORC54_1005	COG2350	Protein conserved in bacteria
FORC54_1006	COG1607	acyl-coa hydrolase
FORC54_1009	COG1301	dicarboxylic acid transport
FORC54_1012	COG0135	phosphoribosylanthranilate isomerase activity
FORC54_1012	COG0134	indole-3-glycerol-phosphate synthase activity
FORC54_1013	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FORC54_1014	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC54_1015	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORC54_1016	COG0613	PHP domain protein
FORC54_1017	COG0009	L-threonylcarbamoyladenylate synthase
FORC54_1023	COG5001	Diguanylate cyclase
FORC54_1024	COG0417	DNA replication proofreading
FORC54_1025	COG2197	response regulator
FORC54_1026	COG0322	excinuclease ABC activity
FORC54_1035	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC54_1036	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC54_1043	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FORC54_1044	COG0437	4 iron, 4 sulfur cluster binding
FORC54_1045	COG3301	Polysulphide reductase, NrfD
FORC54_1046	COG1138	Cytochrome C-type biogenesis protein
FORC54_1048	COG4235	cytochrome complex assembly
FORC54_1048	COG3088	subunit of a heme lyase
FORC54_1051	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC54_1051	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC54_1052	COG0489	protein tyrosine kinase activity
FORC54_1055	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FORC54_1056	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FORC54_1057	COG0659	secondary active sulfate transmembrane transporter activity
FORC54_1058	COG1530	ribonuclease E activity
FORC54_1061	COG1399	metal-binding, possibly nucleic acid-binding protein
FORC54_1064	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC54_1070	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FORC54_1073	COG0084	hydrolase, TatD family'
FORC54_1074	COG1263	PTS System
FORC54_1074	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC54_1076	COG0733	neurotransmitter:sodium symporter activity
FORC54_1078	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC54_1079	COG0469	pyruvate kinase activity
FORC54_1080	COG1940	carbohydrate kinase activity
FORC54_1081	COG0835	chemotaxis
FORC54_1081	COG0784	Response regulator, receiver
FORC54_1082	COG0587	DNA-directed DNA polymerase activity
FORC54_1085	COG1028	Short-chain dehydrogenase reductase Sdr
FORC54_1086	COG0616	signal peptide processing
FORC54_1088	COG0539	negative regulation of cytoplasmic translation
FORC54_1090	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FORC54_1091	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FORC54_1092	COG0284	orotidine-5'-phosphate decarboxylase activity
FORC54_1094	COG4174	ABC transporter (Permease)
FORC54_1095	COG4239	(ABC) transporter, permease
FORC54_1096	COG4166	transmembrane transport
FORC54_1097	COG0444	Belongs to the ABC transporter superfamily
FORC54_1098	COG4608	Belongs to the ABC transporter superfamily
FORC54_1103	COG0583	DNA-binding transcription factor activity
FORC54_1105	COG0686	Belongs to the AlaDH PNT family
FORC54_1109	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FORC54_1117	COG0501	Belongs to the peptidase M48B family
FORC54_1119	COG1028	Short-chain dehydrogenase reductase Sdr
FORC54_1122	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FORC54_1126	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FORC54_1128	COG0482	sulfurtransferase activity
FORC54_1130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC54_1131	COG2916	Histone family protein nucleoid-structuring protein H-NS
FORC54_1132	COG1757	Na H antiporter
FORC54_1134	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FORC54_1135	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FORC54_1136	COG0131	Imidazoleglycerol-phosphate dehydratase
FORC54_1136	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC54_1137	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FORC54_1138	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FORC54_1141	COG3012	SEC-C Motif Domain Protein
FORC54_1142	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FORC54_1143	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC54_1144	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC54_1146	COG1435	thymidine kinase activity
FORC54_1148	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC54_1149	COG0583	DNA-binding transcription factor activity
FORC54_1154	COG2116	formate transmembrane transporter activity
FORC54_1155	COG0390	transport system, permease component
FORC54_1156	COG4459	periplasmic nitrate reductase
FORC54_1157	COG3005	denitrification pathway
FORC54_1158	COG0243	molybdopterin cofactor binding
FORC54_1164	COG1227	inorganic diphosphatase activity
FORC54_1167	COG4172	Belongs to the ABC transporter superfamily
FORC54_1169	COG4171	peptide transport system, permease
FORC54_1170	COG4168	peptide transport system, permease
FORC54_1172	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FORC54_1173	COG1842	Phage shock protein A
FORC54_1175	COG1983	PspC domain protein
FORC54_1179	COG2818	Glycosylase
FORC54_1180	COG0626	cystathionine gamma-synthase activity
FORC54_1182	COG0733	neurotransmitter:sodium symporter activity
FORC54_1184	COG0564	pseudouridine synthase activity
FORC54_1186	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC54_1187	COG1151	hydroxylamine reductase activity
FORC54_1188	COG3604	Transcriptional regulator
FORC54_1189	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FORC54_1190	COG4136	ATPase activity
FORC54_1191	COG4135	transport system, permease component
FORC54_1192	COG4134	Bacterial extracellular solute-binding protein
FORC54_1194	COG3313	Fe-S protein
FORC54_1204	COG2205	protein histidine kinase activity
FORC54_1205	COG0745	RESPONSE REGULATOR receiver
FORC54_1207	COG1061	Type III restriction enzyme res subunit
FORC54_1209	COG2814	Major facilitator Superfamily
FORC54_1211	COG0702	epimerase
FORC54_1212	COG1136	(ABC) transporter
FORC54_1218	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FORC54_1219	COG3273	potassium ion transport
FORC54_1219	COG2985	domain, Protein
FORC54_1220	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC54_1221	COG1979	alcohol dehydrogenase
FORC54_1222	COG3344	reverse transcriptase
FORC54_1223	COG1737	Transcriptional regulator
FORC54_1224	COG0076	glutamate decarboxylase activity
FORC54_1226	COG2431	L-lysine efflux transmembrane transporter activity
FORC54_1228	COG3070	regulator of competence-specific genes
FORC54_1231	COG5002	protein histidine kinase activity
FORC54_1231	COG5002	protein histidine kinase activity
FORC54_1234	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FORC54_1235	COG4988	ABC transporter
FORC54_1236	COG0492	ferredoxin-NADP+ reductase activity
FORC54_1238	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORC54_1240	COG0745	RESPONSE REGULATOR receiver
FORC54_1240	COG3706	GGDEF domain
FORC54_1241	COG0471	metal ion transport
FORC54_1242	COG2949	membrane
FORC54_1243	COG0281	malic enzyme
FORC54_1244	COG1643	Atp-dependent helicase
FORC54_1249	COG1346	cytolysis
FORC54_1250	COG1380	Effector of murein hydrolase LrgA
FORC54_1251	COG2925	Exonuclease
FORC54_1261	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FORC54_1269	COG3063	Type IV pilus biogenesis stability protein PilW
FORC54_1270	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FORC54_1271	COG0737	Belongs to the 5'-nucleotidase family
FORC54_1272	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC54_1274	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FORC54_1276	COG0625	glutathione transferase activity
FORC54_1282	COG1278	Cold shock
FORC54_1284	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FORC54_1285	COG0584	glycerophosphoryl diester phosphodiesterase
FORC54_1286	COG1349	DNA-binding transcription factor activity
FORC54_1287	COG3842	ATPase activity
FORC54_1288	COG0395	ABC-type sugar transport system, permease component
FORC54_1289	COG1175	transmembrane transport
FORC54_1292	COG0730	response to heat
FORC54_1293	COG2197	response regulator
FORC54_1301	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC54_1303	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FORC54_1304	COG0372	Belongs to the citrate synthase family
FORC54_1305	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FORC54_1306	COG2828	Protein conserved in bacteria
FORC54_1312	COG0561	phosphatase activity
FORC54_1313	COG0602	queuosine metabolic process
FORC54_1314	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FORC54_1315	COG3706	GGDEF domain
FORC54_1320	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC54_1323	COG2920	part of a sulfur-relay system
FORC54_1324	COG0670	Belongs to the BI1 family
FORC54_1325	COG1126	abc transporter atp-binding protein
FORC54_1326	COG0765	amino acid transport
FORC54_1327	COG4597	amino acid ABC transporter
FORC54_1328	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC54_1330	COG0437	4 iron, 4 sulfur cluster binding
FORC54_1331	COG0348	domain, Protein
FORC54_1332	COG0204	Acyl-transferase
FORC54_1344	COG1846	Transcriptional regulator
FORC54_1348	COG3971	2-oxopent-4-enoate hydratase activity
FORC54_1355	COG3384	dioxygenase
FORC54_1358	COG1960	acyl-CoA dehydrogenase activity
FORC54_1359	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FORC54_1362	COG1115	amino acid carrier protein
FORC54_1369	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC54_1372	COG3290	protein histidine kinase activity
FORC54_1373	COG4565	transcriptional regulatory protein
FORC54_1374	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FORC54_1375	COG0363	glucosamine-6-phosphate deaminase activity
FORC54_1376	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FORC54_1383	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC54_1385	COG0438	transferase activity, transferring glycosyl groups
FORC54_1392	COG0438	transferase activity, transferring glycosyl groups
FORC54_1394	COG2204	response regulator
FORC54_1400	COG1366	Belongs to the anti-sigma-factor antagonist family
FORC54_1401	COG1793	dna ligase
FORC54_1402	COG3706	GGDEF domain
FORC54_1404	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC54_1407	COG2996	Protein conserved in bacteria
FORC54_1409	COG3008	intermembrane lipid transfer
FORC54_1410	COG2995	paraquat-inducible protein a
FORC54_1411	COG1132	(ABC) transporter
FORC54_1412	COG1956	GAF domain-containing protein
FORC54_1416	COG0308	aminopeptidase N
FORC54_1417	COG2902	Dehydrogenase
FORC54_1420	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC54_1420	COG0116	Belongs to the methyltransferase superfamily
FORC54_1422	COG0488	(ABC) transporter
FORC54_1426	COG1067	ATP-dependent peptidase activity
FORC54_1427	COG3120	sequence-specific DNA binding
FORC54_1432	COG2801	Transposase and inactivated derivatives
FORC54_1446	COG3278	Belongs to the heme-copper respiratory oxidase family
FORC54_1449	COG2010	Cytochrome c
FORC54_1451	COG2217	Heavy metal translocating P-type atpase
FORC54_1454	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC54_1455	COG0589	response to stress
FORC54_1458	COG2992	FlgJ-related protein
FORC54_1461	COG1176	ABC-type spermidine putrescine transport system, permease component I
FORC54_1462	COG1177	transmembrane transport
FORC54_1463	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC54_1464	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC54_1465	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FORC54_1466	COG0004	ammonium transporteR
FORC54_1471	COG0437	4 iron, 4 sulfur cluster binding
FORC54_1472	COG3383	formate dehydrogenase (NAD+) activity
FORC54_1472	COG0243	molybdopterin cofactor binding
FORC54_1478	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC54_1480	COG0488	(ABC) transporter
FORC54_1483	COG3852	Histidine kinase
FORC54_1484	COG2204	response regulator
FORC54_1486	COG4662	Binding-protein-dependent transport system inner membrane component
FORC54_1487	COG3842	ATPase activity
FORC54_1488	COG0746	molybdenum cofactor guanylyltransferase activity
FORC54_1494	COG0840	transmembrane signaling receptor activity
FORC54_1495	COG0791	NLP P60 protein
FORC54_1497	COG3706	GGDEF domain
FORC54_1501	COG0307	riboflavin synthase, alpha
FORC54_1502	COG0534	Mate efflux family protein
FORC54_1520	COG2801	Transposase and inactivated derivatives
FORC54_1583	COG0456	acetyltransferase
FORC54_1587	COG0456	acetyltransferase
FORC54_1587	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC54_1593	COG4628	conserved protein (DUF2132)
FORC54_1600	COG4115	mRNA cleavage
FORC54_1601	COG2161	toxin-antitoxin pair type II binding
FORC54_1620	COG1028	Short-chain dehydrogenase reductase Sdr
FORC54_1633	COG0384	phenazine biosynthesis protein PhzF
FORC54_1703	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC54_1705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC54_1733	COG4628	conserved protein (DUF2132)
FORC54_1755	COG4628	conserved protein (DUF2132)
FORC54_1774	COG4326	sporulation control protein
FORC54_1776	COG1228	amidohydrolase
FORC54_1778	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FORC54_1781	COG5640	endopeptidase activity
FORC54_1782	COG2020	methyltransferase activity
FORC54_1783	COG0247	lactate metabolic process
FORC54_1783	COG0277	FAD linked oxidase domain protein
FORC54_1786	COG2885	chlorophyll binding
FORC54_1789	COG0295	cytidine deaminase activity
FORC54_1798	COG0072	phenylalanine-tRNA ligase activity
FORC54_1798	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC54_1800	COG0745	RESPONSE REGULATOR receiver
FORC54_1800	COG3706	GGDEF domain
FORC54_1813	COG0010	Belongs to the arginase family
FORC54_1814	COG2814	Major facilitator Superfamily
FORC54_1815	COG5380	lipid catabolic process
FORC54_1816	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FORC54_1821	COG1643	Atp-dependent helicase
FORC54_1823	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FORC54_1831	COG2894	cell division
FORC54_1833	COG4964	Belongs to the GSP D family
FORC54_1844	COG3706	GGDEF domain
FORC54_1846	COG0443	Heat shock 70 kDa protein
FORC54_1847	COG0443	Heat shock 70 kDa protein
FORC54_1859	COG0438	transferase activity, transferring glycosyl groups
FORC54_1859	COG0297	glycogen (starch) synthase activity
FORC54_1860	COG0438	transferase activity, transferring glycosyl groups
FORC54_1865	COG1596	polysaccharide export
FORC54_1868	COG1115	amino acid carrier protein
FORC54_1869	COG1132	(ABC) transporter
FORC54_1870	COG1132	(ABC) transporter
FORC54_1873	COG0783	Belongs to the Dps family
FORC54_1876	COG0814	amino acid
FORC54_1877	COG1597	lipid kinase activity
FORC54_1879	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC54_1880	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC54_1883	COG0583	DNA-binding transcription factor activity
FORC54_1884	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC54_1885	COG1328	CTP reductase activity
FORC54_1886	COG5001	Diguanylate cyclase
FORC54_1886	COG3300	MHYT domain
FORC54_1889	COG2200	EAL domain
FORC54_1889	COG2199	diguanylate cyclase activity
FORC54_1890	COG3706	GGDEF domain
FORC54_1892	COG4191	Histidine kinase
FORC54_1892	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC54_1893	COG0471	metal ion transport
FORC54_1896	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC54_1897	COG3283	Transcriptional regulator of aromatic amino acids metabolism
FORC54_1898	COG3768	UPF0283 membrane protein
FORC54_1899	COG3106	COG3106 Predicted ATPase
FORC54_1905	COG0494	nUDIX hydrolase
FORC54_1906	COG0814	amino acid
FORC54_1907	COG1760	l-serine dehydratase
FORC54_1908	COG2200	EAL domain
FORC54_1910	COG0720	synthase
FORC54_1915	COG3437	response regulator, receiver
FORC54_1915	COG2770	Histidine kinase
FORC54_1916	COG1448	Aminotransferase
FORC54_1920	COG0840	transmembrane signaling receptor activity
FORC54_1921	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC54_1922	COG1846	Transcriptional regulator
FORC54_1927	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FORC54_1930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC54_1931	COG3108	Peptidase M15
FORC54_1932	COG2989	Protein conserved in bacteria
FORC54_1939	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC54_1941	COG0653	protein targeting
FORC54_1943	COG3706	GGDEF domain
FORC54_1943	COG0745	RESPONSE REGULATOR receiver
FORC54_1944	COG0366	Alpha amylase catalytic
FORC54_1946	COG4120	Belongs to the binding-protein-dependent transport system permease family
FORC54_1948	COG3092	negative regulation of chromosome organization
FORC54_1950	COG0857	belongs to the CobB CobQ family
FORC54_1950	COG0280	phosphate acetyltransferase
FORC54_1952	COG0583	DNA-binding transcription factor activity
FORC54_1957	COG1032	radical SAM domain protein
FORC54_1961	COG2207	Transcriptional regulator
FORC54_1966	COG0861	Integral membrane protein TerC family
FORC54_1967	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC54_1968	COG0840	transmembrane signaling receptor activity
FORC54_1969	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC54_1972	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC54_1986	COG1715	Restriction endonuclease
FORC54_1991	COG2205	protein histidine kinase activity
FORC54_1991	COG0784	Response regulator, receiver
FORC54_1994	COG0754	glutathionylspermidine amidase activity
FORC54_1996	COG3766	membrane
FORC54_1998	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FORC54_1999	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FORC54_2000	COG2885	chlorophyll binding
FORC54_2001	COG0823	Involved in the tonB-independent uptake of proteins
FORC54_2004	COG0811	peptide transport
FORC54_2005	COG0824	Thioesterase
FORC54_2007	COG4890	Cyd operon protein YbgT
FORC54_2008	COG1294	oxidase, subunit
FORC54_2009	COG1271	oxidase subunit
FORC54_2010	COG2255	four-way junction helicase activity
FORC54_2015	COG4106	trans-aconitate 2-methyltransferase activity
FORC54_2017	COG4067	protein conserved in archaea
FORC54_2017	COG0189	ligase activity
FORC54_2020	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FORC54_2022	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FORC54_2023	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC54_2024	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FORC54_2025	COG0745	RESPONSE REGULATOR receiver
FORC54_2028	COG3070	regulator of competence-specific genes
FORC54_2033	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC54_2035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC54_2037	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FORC54_2040	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FORC54_2041	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FORC54_2042	COG0542	response to heat
FORC54_2044	COG1278	Cold shock
FORC54_2048	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FORC54_2049	COG1199	ATP-dependent helicase activity
FORC54_2051	COG3923	Primosomal replication protein n
FORC54_2053	COG0840	transmembrane signaling receptor activity
FORC54_2054	COG0708	Exodeoxyribonuclease III
FORC54_2057	COG4215	(ABC) transporter
FORC54_2062	COG1882	Formate acetyltransferase
FORC54_2065	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC54_2068	COG2766	serine protein kinase
FORC54_2069	COG2718	Belongs to the UPF0229 family
FORC54_2070	COG2719	SpoVR family
FORC54_2071	COG2199	diguanylate cyclase activity
FORC54_2072	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FORC54_2074	COG1663	tetraacyldisaccharide 4'-kinase activity
FORC54_2076	COG2333	competence protein COMEC
FORC54_2076	COG0658	competence protein
FORC54_2078	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC54_2080	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC54_2082	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FORC54_2085	COG1252	NADH dehydrogenase
FORC54_2091	COG0537	adenosine 5'-monophosphoramidase activity
FORC54_2096	COG4109	DRTGG domain
FORC54_2097	COG3706	GGDEF domain
FORC54_2098	COG1982	Orn Lys Arg decarboxylase major
FORC54_2099	COG0531	amino acid
FORC54_2101	COG3710	Transcriptional regulator
FORC54_2102	COG2199	diguanylate cyclase activity
FORC54_2102	COG2203	Gaf domain
FORC54_2103	COG2239	Acts as a magnesium transporter
FORC54_2105	COG2226	methyltransferase
FORC54_2108	COG1785	Belongs to the alkaline phosphatase family
FORC54_2112	COG2983	Belongs to the UPF0260 family
FORC54_2115	COG0745	RESPONSE REGULATOR receiver
FORC54_2116	COG2205	protein histidine kinase activity
FORC54_2120	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FORC54_2124	COG0745	RESPONSE REGULATOR receiver
FORC54_2125	COG0583	DNA-binding transcription factor activity
FORC54_2126	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FORC54_2127	COG1286	toxin biosynthetic process
FORC54_2128	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FORC54_2129	COG0285	dihydrofolate synthase activity
FORC54_2133	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC54_2135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC54_2138	COG3101	peptidyl-lysine hydroxylation
FORC54_2139	COG2860	membrane
FORC54_2141	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC54_2142	COG2840	Smr protein MutS2
FORC54_2143	COG2062	phosphohistidine phosphatase, SixA
FORC54_2144	COG1025	Belongs to the peptidase M16 family
FORC54_2149	COG2067	long-chain fatty acid transport protein
FORC54_2150	COG2067	long-chain fatty acid transport protein
FORC54_2151	COG2853	Lipoprotein
FORC54_2153	COG4235	cytochrome complex assembly
FORC54_2153	COG3088	subunit of a heme lyase
FORC54_2154	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC54_2155	COG1138	Cytochrome C-type biogenesis protein
FORC54_2157	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC54_2158	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC54_2159	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC54_2160	COG4133	protoheme IX ABC transporter activity
FORC54_2162	COG0835	chemotaxis
FORC54_2164	COG1192	Involved in chromosome partitioning
FORC54_2166	COG2198	Histidine kinase
FORC54_2166	COG0643	Histidine kinase
FORC54_2167	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FORC54_2170	COG0455	bacterial-type flagellum organization
FORC54_2174	COG1684	flagellar biosynthetic protein fliR
FORC54_2175	COG1987	bacterial-type flagellum assembly
FORC54_2185	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC54_2187	COG1677	Flagellar hook-basal body complex protein FliE
FORC54_2188	COG2204	response regulator
FORC54_2189	COG4191	Histidine kinase
FORC54_2190	COG2204	response regulator
FORC54_2191	COG1516	flagellar protein fliS
FORC54_2193	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FORC54_2194	COG1334	flagellar protein FlaG
FORC54_2195	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC54_2196	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC54_2197	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC54_2198	COG2837	iron assimilation
FORC54_2203	COG1393	Belongs to the ArsC family
FORC54_2208	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC54_2209	COG2716	regulation of RNA biosynthetic process
FORC54_2210	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FORC54_2213	COG4783	chaperone-mediated protein folding
FORC54_2214	COG1393	Belongs to the ArsC family
FORC54_2218	COG2233	PERMEase
FORC54_2219	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FORC54_2221	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FORC54_2222	COG0121	glutamine amidotransferase
FORC54_2224	COG1960	acyl-CoA dehydrogenase activity
FORC54_2229	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC54_2231	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC54_2233	COG2226	methyltransferase
FORC54_2234	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC54_2235	COG0741	lytic transglycosylase activity
FORC54_2235	COG1388	LysM domain
FORC54_2237	COG3021	interspecies interaction between organisms
FORC54_2238	COG0347	Belongs to the P(II) protein family
FORC54_2242	COG0587	DNA-directed DNA polymerase activity
FORC54_2248	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FORC54_2249	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC54_2250	COG0750	zinc metalloprotease
FORC54_2252	COG0575	Belongs to the CDS family
FORC54_2254	COG0233	cytoplasmic translational termination
FORC54_2258	COG0024	Methionine aminopeptidase
FORC54_2259	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FORC54_2262	COG3098	single-species biofilm formation
FORC54_2268	COG1671	Belongs to the UPF0178 family
FORC54_2269	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FORC54_2271	COG0254	rRNA binding
FORC54_2272	COG1720	tRNA m6t6A37 methyltransferase activity
FORC54_2277	COG0733	neurotransmitter:sodium symporter activity
FORC54_2280	COG0514	ATP-dependent DNA helicase (RecQ)
FORC54_2282	COG3706	GGDEF domain
FORC54_2282	COG0745	RESPONSE REGULATOR receiver
FORC54_2284	COG1477	protein flavinylation
FORC54_2291	COG0271	Belongs to the BolA IbaG family
FORC54_2295	COG2211	Major facilitator Superfamily
FORC54_2297	COG1595	DNA-templated transcription, initiation
FORC54_2300	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FORC54_2301	COG0693	protein deglycase activity
FORC54_2302	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORC54_2305	COG2166	iron-sulfur cluster assembly
FORC54_2306	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FORC54_2307	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FORC54_2311	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC54_2312	COG1074	ATP-dependent DNA helicase activity
FORC54_2313	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FORC54_2314	COG3083	sulfuric ester hydrolase activity
FORC54_2317	COG3141	response to X-ray
FORC54_2318	COG2171	N-acyltransferase activity
FORC54_2320	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FORC54_2322	COG1349	DNA-binding transcription factor activity
FORC54_2323	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC54_2326	COG0569	domain protein
FORC54_2326	COG0189	ligase activity
FORC54_2329	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC54_2331	COG0840	transmembrane signaling receptor activity
FORC54_2332	COG2017	converts alpha-aldose to the beta-anomer
FORC54_2335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC54_2336	COG1609	Transcriptional regulator
FORC54_2338	COG3250	beta-galactosidase activity
FORC54_2339	COG2731	YhcH YjgK YiaL family protein
FORC54_2340	COG0531	amino acid
FORC54_2341	COG0531	amino acid
FORC54_2343	COG3408	Glycogen debranching enzyme
FORC54_2343	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FORC54_2346	COG0583	DNA-binding transcription factor activity
FORC54_2347	COG2059	Chromate
FORC54_2357	COG4964	Belongs to the GSP D family
FORC54_2365	COG1022	Amp-dependent synthetase and ligase
FORC54_2366	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC54_2370	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FORC54_2372	COG0560	Phosphoserine phosphatase
FORC54_2377	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FORC54_2378	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC54_2379	COG0084	hydrolase, TatD family'
FORC54_2381	COG3706	GGDEF domain
FORC54_2383	COG0456	acetyltransferase
FORC54_2385	COG3153	acetyltransferase
FORC54_2390	COG0534	Mate efflux family protein
FORC54_2392	COG4785	May be involved in cell division
FORC54_2401	COG0195	Participates in both transcription termination and antitermination
FORC54_2403	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC54_2405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FORC54_2406	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FORC54_2408	COG1534	Rna-binding protein
FORC54_2412	COG2027	D-alanyl-D-alanine carboxypeptidase
FORC54_2413	COG2832	Protein of unknown function (DUF454)
FORC54_2415	COG0739	heme binding
FORC54_2420	COG0628	permease
FORC54_2422	COG2205	protein histidine kinase activity
FORC54_2422	COG0784	Response regulator, receiver
FORC54_2424	COG0601	transmembrane transport
FORC54_2425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC54_2426	COG0444	Belongs to the ABC transporter superfamily
FORC54_2427	COG4608	Belongs to the ABC transporter superfamily
FORC54_2429	COG2971	BadF BadG BcrA BcrD
FORC54_2432	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC54_2433	COG3842	ATPase activity
FORC54_2435	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC54_2436	COG0004	ammonium transporteR
FORC54_2437	COG0347	Belongs to the P(II) protein family
FORC54_2439	COG3835	regulator
FORC54_2440	COG2610	gluconate transmembrane transporter activity
FORC54_2441	COG1929	Belongs to the glycerate kinase type-1 family
FORC54_2442	COG1049	propionate catabolic process, 2-methylcitrate cycle
FORC54_2443	COG1752	Esterase of the alpha-beta hydrolase superfamily
FORC54_2444	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC54_2445	COG1643	Atp-dependent helicase
FORC54_2446	COG1489	DNA binding
FORC54_2447	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FORC54_2450	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC54_2453	COG0842	Transport permease protein
FORC54_2454	COG1131	(ABC) transporter
FORC54_2455	COG0659	secondary active sulfate transmembrane transporter activity
FORC54_2456	COG0288	reversible hydration of carbon dioxide
FORC54_2459	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC54_2460	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC54_2461	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FORC54_2462	COG2186	Transcriptional regulator
FORC54_2464	COG3023	N-Acetylmuramoyl-L-alanine amidase
FORC54_2467	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC54_2468	COG1459	type II secretion system
FORC54_2470	COG0237	dephospho-CoA kinase activity
FORC54_2476	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FORC54_2477	COG4137	Cytochrome C assembly protein
FORC54_2478	COG4536	flavin adenine dinucleotide binding
FORC54_2482	COG0612	Peptidase, M16
FORC54_2483	COG1238	metal cluster binding
FORC54_2485	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FORC54_2486	COG0511	ligase activity, forming carbon-carbon bonds
FORC54_2486	COG5016	pyruvate
FORC54_2490	COG0527	aspartate kinase activity
FORC54_2491	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC54_2495	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FORC54_2496	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORC54_2497	COG1388	LysM domain
FORC54_2497	COG4942	peptidase
FORC54_2500	COG0585	pseudouridine synthase activity
FORC54_2501	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FORC54_2507	COG3956	TIGRFAM MazG family protein
FORC54_2508	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC54_2509	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC54_2510	COG2205	protein histidine kinase activity
FORC54_2510	COG3437	response regulator, receiver
FORC54_2510	COG3850	Histidine kinase
FORC54_2510	COG4999	Histidine kinase
FORC54_2511	COG5001	Diguanylate cyclase
FORC54_2514	COG0736	holo-[acyl-carrier-protein] synthase activity
FORC54_2516	COG1381	Involved in DNA repair and RecF pathway recombination
FORC54_2519	COG0681	Belongs to the peptidase S26 family
FORC54_2521	COG3086	response to oxidative stress
FORC54_2524	COG1595	DNA-templated transcription, initiation
FORC54_2525	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FORC54_2528	COG0354	folic acid binding
FORC54_2531	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC54_2532	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC54_2533	COG3079	Belongs to the UPF0149 family
FORC54_2534	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FORC54_2535	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FORC54_2537	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC54_2540	COG1279	arginine transmembrane transporter activity
FORC54_2541	COG0668	transmembrane transport
FORC54_2542	COG0191	fructose-bisphosphate aldolase activity
FORC54_2544	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC54_2550	COG2356	endonuclease I
FORC54_2551	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FORC54_2557	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FORC54_2558	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC54_2559	COG0762	integral membrane protein
FORC54_2563	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC54_2568	COG0741	lytic transglycosylase activity
FORC54_2574	COG1609	Transcriptional regulator
FORC54_2575	COG3394	polysaccharide catabolic process
FORC54_2576	COG1486	melibiose metabolic process
FORC54_2577	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC54_2579	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC54_2580	COG0726	polysaccharide deacetylase
FORC54_2582	COG0795	lipopolysaccharide-transporting ATPase activity
FORC54_2583	COG0795	lipopolysaccharide-transporting ATPase activity
FORC54_2585	COG2927	DNA polymerase III (CHI subunit)
FORC54_2588	COG4269	membrane
FORC54_2590	COG0456	acetyltransferase
FORC54_2597	COG0251	oxidation-reduction process
FORC54_2598	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC54_2600	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC54_2601	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FORC54_2602	COG0312	modulator of DNA gyrase
FORC54_2603	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC54_2604	COG3164	Protein of unknown function
FORC54_2605	COG1530	ribonuclease E activity
FORC54_2607	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FORC54_2608	COG1792	Involved in formation and maintenance of cell shape
FORC54_2609	COG1077	Cell shape determining protein MreB Mrl
FORC54_2618	COG1459	type II secretion system
FORC54_2619	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC54_2621	COG3267	Type II secretory pathway component ExeA
FORC54_2621	COG3409	Peptidoglycan-binding domain 1 protein
FORC54_2626	COG2200	EAL domain
FORC54_2626	COG2199	diguanylate cyclase activity
FORC54_2632	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FORC54_2633	COG0527	aspartate kinase activity
FORC54_2634	COG1410	methionine synthase
FORC54_2634	COG0646	methionine synthase
FORC54_2636	COG0745	RESPONSE REGULATOR receiver
FORC54_2636	COG3706	GGDEF domain
FORC54_2639	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC54_2645	COG0735	belongs to the Fur family
FORC54_2648	COG0432	Pfam Uncharacterised protein family UPF0047
FORC54_2650	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC54_2651	COG0305	Participates in initiation and elongation during chromosome replication
FORC54_2657	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FORC54_2658	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FORC54_2667	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FORC54_2673	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FORC54_2674	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC54_2675	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FORC54_2677	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FORC54_2678	COG0527	aspartate kinase activity
FORC54_2678	COG0460	homoserine dehydrogenase
FORC54_2679	COG0626	cystathionine gamma-synthase activity
FORC54_2681	COG0281	malic enzyme
FORC54_2683	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FORC54_2684	COG1609	Transcriptional regulator
FORC54_2688	COG1575	Belongs to the MenA family. Type 1 subfamily
FORC54_2691	COG1494	fructose-1,6-bisphosphatase
FORC54_2697	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC54_2699	COG2906	2 iron, 2 sulfur cluster binding
FORC54_2701	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC54_2706	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FORC54_2707	COG2964	Protein conserved in bacteria
FORC54_2708	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC54_2712	COG1047	Peptidyl-prolyl cis-trans
FORC54_2715	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC54_2716	COG0488	(ABC) transporter
FORC54_2718	COG0429	hydrolase of the alpha beta-hydrolase fold
FORC54_2720	COG3954	Phosphoribulokinase
FORC54_2721	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC54_2725	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FORC54_2730	COG0180	Tryptophanyl-tRNA synthetase
FORC54_2731	COG0546	phosphoglycolate phosphatase activity
FORC54_2733	COG0557	exoribonuclease II activity
FORC54_2734	COG0402	S-adenosylhomocysteine deaminase activity
FORC54_2737	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FORC54_2738	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FORC54_2739	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FORC54_2740	COG0330	HflC and HflK could
FORC54_2741	COG0330	HflC and HflK could
FORC54_2742	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FORC54_2745	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FORC54_2746	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC54_2747	COG0802	atpase or kinase
FORC54_2748	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FORC54_2752	COG0471	metal ion transport
FORC54_2754	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FORC54_2756	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC54_2759	COG1045	serine acetyltransferase
FORC54_2760	COG4942	peptidase
FORC54_2766	COG1053	succinate dehydrogenase
FORC54_2767	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FORC54_2769	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FORC54_2773	COG1509	lysine 2,3-aminomutase activity
FORC54_2774	COG1285	pathogenesis
FORC54_2778	COG0534	Mate efflux family protein
FORC54_2781	COG3678	ATP-independent chaperone mediated protein folding
FORC54_2782	COG0745	RESPONSE REGULATOR receiver
FORC54_2783	COG2205	protein histidine kinase activity
FORC54_2784	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FORC54_2785	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FORC54_2787	COG1027	Aspartate ammonia-lyase
FORC54_2788	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC54_2789	COG4232	protein-disulfide reductase activity
FORC54_2791	COG2095	MarC family integral membrane protein
FORC54_2793	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC54_2796	COG2205	protein histidine kinase activity
FORC54_2796	COG2198	Histidine kinase
FORC54_2796	COG0784	Response regulator, receiver
FORC54_2797	COG2814	Major facilitator Superfamily
FORC54_2800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC54_2802	COG0511	ligase activity, forming carbon-carbon bonds
FORC54_2803	COG0439	Biotin carboxylase
FORC54_2804	COG2264	protein methyltransferase activity
FORC54_2806	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FORC54_2807	COG0840	transmembrane signaling receptor activity
FORC54_2808	COG0789	Transcriptional regulator
FORC54_2813	COG1253	flavin adenine dinucleotide binding
FORC54_2814	COG3068	Protein conserved in bacteria
FORC54_2815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC54_2816	COG1573	uracil-dna glycosylase
FORC54_2822	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FORC54_2830	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC54_2834	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FORC54_2836	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC54_2838	COG3335	DDE superfamily endonuclease
FORC54_2842	COG4206	TonB-dependent receptor
FORC54_2848	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FORC54_2849	COG0328	RNA-DNA hybrid ribonuclease activity
FORC54_2851	COG2003	Belongs to the UPF0758 family
FORC54_2861	COG0328	RNA-DNA hybrid ribonuclease activity
FORC54_2873	COG2937	Belongs to the GPAT DAPAT family
FORC54_2875	COG3161	chorismate lyase activity
FORC54_2876	COG1580	Controls the rotational direction of flagella during chemotaxis
FORC54_2877	COG0705	Rhomboid family
FORC54_2880	COG2177	Part of the ABC transporter FtsEX involved in
FORC54_2881	COG2884	Cell division ATP-binding protein ftsE
FORC54_2882	COG0552	protein localization to endoplasmic reticulum
FORC54_2883	COG0742	ribosomal rna small subunit methyltransferase
FORC54_2885	COG2095	MarC family integral membrane protein
FORC54_2893	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC54_2894	COG0640	Transcriptional regulator
FORC54_2895	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FORC54_2896	COG1280	lysine exporter protein (LysE YggA)
FORC54_2897	COG2267	carboxylic ester hydrolase activity
FORC54_2898	COG0561	phosphatase activity
FORC54_2902	COG3287	FIST C domain
FORC54_2902	COG2199	diguanylate cyclase activity
FORC54_2902	COG2200	EAL domain
FORC54_2903	COG1011	Hydrolase
FORC54_2907	COG0019	diaminopimelate decarboxylase activity
FORC54_2914	COG2959	enzyme of heme biosynthesis
FORC54_2916	COG2081	HI0933 family
FORC54_2918	COG1528	Iron-storage protein
FORC54_2919	COG0589	response to stress
FORC54_2922	COG0742	ribosomal rna small subunit methyltransferase
FORC54_2923	COG5002	protein histidine kinase activity
FORC54_2923	COG5001	Diguanylate cyclase
FORC54_2924	COG1522	sequence-specific DNA binding
FORC54_2926	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FORC54_2927	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC54_2928	COG0800	Aldolase
FORC54_2929	COG2610	gluconate transmembrane transporter activity
FORC54_2930	COG3265	gluconokinase activity
FORC54_2931	COG0129	dihydroxy-acid dehydratase activity
FORC54_2932	COG1609	Transcriptional regulator
FORC54_2935	COG2815	serine threonine protein kinase
FORC54_2935	COG0515	serine threonine protein kinase
FORC54_2942	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC54_2944	COG4166	transmembrane transport
FORC54_2945	COG4172	Belongs to the ABC transporter superfamily
FORC54_2949	COG1309	transcriptional regulator
FORC54_2950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC54_2951	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC54_2952	COG2960	long-chain fatty acid transporting porin activity
FORC54_2954	COG0583	DNA-binding transcription factor activity
FORC54_2956	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FORC54_2958	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FORC54_2959	COG0408	coproporphyrinogen oxidase activity
FORC54_2963	COG0551	DNA topoisomerase type I activity
FORC54_2965	COG0758	DNA mediated transformation
FORC54_2968	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FORC54_2969	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC54_2969	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC54_2970	COG0569	domain protein
FORC54_2971	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC54_2972	COG1272	protein, Hemolysin III
FORC54_2973	COG4326	sporulation control protein
FORC54_2975	COG3084	Protein conserved in bacteria
FORC54_2977	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FORC54_2978	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC54_2979	COG0204	Acyl-transferase
FORC54_2981	COG0606	chelatase, subunit chli
FORC54_2983	COG3978	acetolactate synthase activity
FORC54_2984	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC54_2985	COG0129	dihydroxy-acid dehydratase activity
FORC54_2987	COG0583	DNA-binding transcription factor activity
FORC54_2988	COG2814	Major facilitator Superfamily
FORC54_2990	COG0765	amino acid transport
FORC54_3000	COG3312	ion transport
FORC54_3001	COG1475	DNA binding
FORC54_3002	COG1192	Involved in chromosome partitioning
FORC54_3004	COG0445	tRNA wobble uridine modification
FORC54_3005	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FORC54_3007	COG0706	membrane insertase activity
FORC54_3010	COG1126	abc transporter atp-binding protein
FORC54_3015	COG4608	Belongs to the ABC transporter superfamily
FORC54_3016	COG0444	Belongs to the ABC transporter superfamily
FORC54_3018	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FORC54_3018	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC54_3022	COG0217	transcriptional regulatory protein
FORC54_3025	COG1136	(ABC) transporter
FORC54_3026	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC54_3029	COG3275	phosphorelay sensor kinase activity
FORC54_3034	COG0786	glutamate:sodium symporter activity
FORC54_3035	COG0786	glutamate:sodium symporter activity
FORC54_3043	COG3344	reverse transcriptase
FORC54_3046	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC54_3047	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC54_3048	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC54_3052	COG1309	transcriptional regulator
FORC54_3058	COG1741	Belongs to the pirin family
FORC54_3060	COG5001	Diguanylate cyclase
FORC54_3061	COG3706	GGDEF domain
FORC54_3072	COG1982	Orn Lys Arg decarboxylase major
FORC54_3073	COG0531	amino acid
FORC54_3080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC54_3081	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FORC54_3082	COG1162	GTPase activity
FORC54_3083	COG2847	Copper chaperone PCu(A)C
FORC54_3084	COG1999	signal sequence binding
FORC54_3091	COG0058	SHG alpha-glucan phosphorylase activity
FORC54_3092	COG1640	4-alpha-glucanotransferase
FORC54_3093	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FORC54_3094	COG0840	transmembrane signaling receptor activity
FORC54_3095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC54_3101	COG2184	nucleotidyltransferase activity
FORC54_3102	COG0560	Phosphoserine phosphatase
FORC54_3105	COG1012	belongs to the aldehyde dehydrogenase family
FORC54_3106	COG0625	glutathione transferase activity
FORC54_3107	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC54_3108	COG1283	sodium-dependent phosphate transmembrane transporter activity
FORC54_3109	COG0612	Peptidase, M16
FORC54_3111	COG0583	DNA-binding transcription factor activity
FORC54_3113	COG0642	Histidine kinase
FORC54_3114	COG0745	RESPONSE REGULATOR receiver
FORC54_3115	COG2199	diguanylate cyclase activity
FORC54_3120	COG1609	Transcriptional regulator
FORC54_3123	COG0395	ABC-type sugar transport system, permease component
FORC54_3124	COG2723	6-phospho-beta-galactosidase activity
FORC54_3126	COG1609	Transcriptional regulator
FORC54_3129	COG0747	negative chemotaxis
FORC54_3131	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC54_3132	COG0444	Belongs to the ABC transporter superfamily
FORC54_3133	COG4608	Belongs to the ABC transporter superfamily
FORC54_3135	COG1609	Transcriptional regulator
FORC54_3139	COG4580	involved in the transport of maltose and maltodextrins
FORC54_3142	COG1472	Belongs to the glycosyl hydrolase 3 family
FORC54_3143	COG0534	Mate efflux family protein
FORC54_3145	COG1566	PFAM secretion protein HlyD family protein
FORC54_3150	COG0564	pseudouridine synthase activity
FORC54_3155	COG1609	Transcriptional regulator
FORC54_3157	COG1129	ABC transporter
FORC54_3162	COG2211	Major facilitator Superfamily
FORC54_3163	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC54_3164	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FORC54_3166	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FORC54_3167	COG2188	Transcriptional regulator
FORC54_3168	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC54_3168	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC54_3168	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC54_3169	COG0383	alpha-mannosidase activity
FORC54_3170	COG1929	Belongs to the glycerate kinase type-1 family
FORC54_3171	COG1482	cell wall glycoprotein biosynthetic process
FORC54_3179	COG1482	cell wall glycoprotein biosynthetic process
FORC54_3180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC54_3180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC54_3180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC54_3181	COG2207	Transcriptional regulator
FORC54_3183	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC54_3184	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC54_3186	COG3537	Alpha-1,2-mannosidase
FORC54_3187	COG3537	Alpha-1,2-mannosidase
FORC54_3188	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC54_3189	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC54_3189	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC54_3189	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC54_3192	COG3383	formate dehydrogenase (NAD+) activity
FORC54_3194	COG1609	Transcriptional regulator
FORC54_3195	COG1263	PTS System
FORC54_3195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC54_3196	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FORC54_3197	COG1482	cell wall glycoprotein biosynthetic process
FORC54_3198	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FORC54_3199	COG0583	DNA-binding transcription factor activity
FORC54_3206	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FORC54_3210	COG0583	DNA-binding transcription factor activity
FORC54_3213	COG0137	argininosuccinate synthase activity
FORC54_3215	COG1301	dicarboxylic acid transport
FORC54_3224	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC54_3225	COG2175	clavaminate synthase activity
FORC54_3232	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC54_3234	COG3706	GGDEF domain
FORC54_3237	COG2356	endonuclease I
FORC54_3240	COG1368	sulfuric ester hydrolase activity
FORC54_3241	COG2194	sulfuric ester hydrolase activity
FORC54_3242	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC54_3243	COG2205	protein histidine kinase activity
FORC54_3244	COG0745	RESPONSE REGULATOR receiver
FORC54_3248	COG4221	oxidoreductase activity
FORC54_3253	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC54_3254	COG0076	glutamate decarboxylase activity
FORC54_3257	COG0561	phosphatase activity
FORC54_3260	COG0671	phosphoesterase, PA-phosphatase related
FORC54_3261	COG0351	phosphomethylpyrimidine kinase
FORC54_3267	COG2814	Major facilitator Superfamily
FORC54_3271	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC54_3272	COG4771	TonB-dependent receptor
FORC54_3276	COG0393	Putative heavy-metal-binding
FORC54_3279	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC54_3281	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FORC54_3285	COG0753	catalase activity
FORC54_3289	COG0346	lactoylglutathione lyase activity
FORC54_3291	COG2211	Major facilitator Superfamily
FORC54_3294	COG3240	lipase activity
FORC54_3304	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FORC54_3306	COG3646	Phage regulatory protein
FORC54_3308	COG0582	viral genome integration into host DNA
FORC54_3321	COG4626	Terminase
FORC54_3321	COG1802	Transcriptional regulator
FORC54_3327	COG1403	HNH endonuclease
FORC54_3329	COG0037	tRNA processing
FORC54_3336	COG3772	lysozyme
FORC54_3342	COG1030	water channel activity
FORC54_3369	COG3040	lipid binding
FORC54_3377	COG3111	PFAM Bacterial OB fold (BOF) protein
FORC54_3379	COG2274	protein secretion by the type I secretion system
FORC54_3381	COG1538	Outer membrane efflux protein
FORC54_3385	COG0668	transmembrane transport
FORC54_3390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC54_3391	COG4946	Tricorn protease homolog
FORC54_3391	COG0793	Belongs to the peptidase S41A family
FORC54_3394	COG1122	ATPase activity
FORC54_3395	COG4720	Psort location CytoplasmicMembrane, score
FORC54_3396	COG1566	PFAM secretion protein HlyD family protein
FORC54_3398	COG3706	GGDEF domain
FORC54_3402	COG3272	Protein of unknown function (DUF1722)
FORC54_3403	COG0789	Transcriptional regulator
FORC54_3404	COG0415	Belongs to the DNA photolyase family
FORC54_3405	COG1388	LysM domain
FORC54_3405	COG1376	ErfK ybiS ycfS ynhG family protein
FORC54_3407	COG0513	Belongs to the DEAD box helicase family
FORC54_3415	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC54_3416	COG0573	inorganic phosphate transmembrane transporter activity
FORC54_3417	COG0581	inorganic phosphate transmembrane transporter activity
FORC54_3419	COG2203	Gaf domain
FORC54_3419	COG3706	GGDEF domain
FORC54_3419	COG5001	Diguanylate cyclase
FORC54_3419	COG4251	negative regulation of phosphorylation
FORC54_3421	COG2304	oxidoreductase activity
FORC54_3425	COG0714	Associated with various cellular activities
FORC54_3439	COG1596	polysaccharide export
FORC54_3441	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC54_3452	COG2354	Protein conserved in bacteria
FORC54_3454	COG0418	dihydroorotase activity
FORC54_3455	COG0633	Ferredoxin
FORC54_3455	COG3217	Mosc domain protein beta barrel domain protein
FORC54_3455	COG0633	Ferredoxin
FORC54_3455	COG3217	Mosc domain protein beta barrel domain protein
FORC54_3456	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FORC54_3465	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FORC54_3466	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC54_3468	COG0848	biopolymer transport protein
FORC54_3469	COG0811	peptide transport
FORC54_3470	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FORC54_3473	COG3721	Heme iron utilization protein
FORC54_3474	COG0748	coenzyme F420 binding
FORC54_3476	COG0784	Response regulator, receiver
FORC54_3476	COG0835	chemotaxis
FORC54_3477	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC54_3478	COG0589	response to stress
FORC54_3479	COG0366	Alpha amylase catalytic
FORC54_3481	COG0840	transmembrane signaling receptor activity
FORC54_3489	COG0739	heme binding
FORC54_3490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC54_3493	COG2084	Dehydrogenase
FORC54_3497	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC54_3501	COG0840	transmembrane signaling receptor activity
FORC54_3504	COG3706	GGDEF domain
FORC54_3505	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC54_3505	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC54_3506	COG1765	OsmC-like protein
FORC54_3507	COG2171	N-acyltransferase activity
FORC54_3511	COG1011	Hydrolase
FORC54_3516	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC54_3517	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC54_3517	COG2207	Transcriptional regulator
FORC54_3520	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FORC54_3521	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC54_3527	COG3842	ATPase activity
FORC54_3532	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC54_3533	COG0583	DNA-binding transcription factor activity
FORC54_3536	COG1760	l-serine dehydratase
FORC54_3540	COG1686	Belongs to the peptidase S11 family
FORC54_3545	COG1309	transcriptional regulator
FORC54_3546	COG1012	belongs to the aldehyde dehydrogenase family
FORC54_3550	COG4175	Glycine betaine
FORC54_3551	COG3059	membrane
FORC54_3557	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC54_3558	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
FORC54_3559	COG0247	lactate metabolic process
FORC54_3562	COG1619	proteins homologs of microcin C7 resistance protein MccF
FORC54_3563	COG2133	pyrroloquinoline quinone binding
FORC54_3565	COG1454	alcohol dehydrogenase
FORC54_3566	COG0443	Heat shock 70 kDa protein
FORC54_3567	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC54_3573	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC54_3574	COG3174	membrane
FORC54_3579	COG0814	amino acid
FORC54_3580	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FORC54_3585	COG2962	Rard protein
FORC54_3588	COG0671	phosphoesterase, PA-phosphatase related
FORC54_3590	COG1288	antiporter activity
FORC54_3593	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FORC54_3596	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FORC54_3597	COG2315	Protein conserved in bacteria
FORC54_3601	COG1129	ABC transporter
FORC54_3602	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC54_3603	COG1879	ABC-type sugar transport system periplasmic component
FORC54_3604	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC54_3605	COG1609	Transcriptional regulator
FORC54_3607	COG0784	Response regulator, receiver
FORC54_3607	COG0835	chemotaxis
FORC54_3609	COG0456	acetyltransferase
FORC54_3613	COG0420	3'-5' exonuclease activity
FORC54_3614	COG0419	ATPase involved in DNA repair
FORC54_3616	COG0583	DNA-binding transcription factor activity
FORC54_3620	COG4964	Belongs to the GSP D family
FORC54_3636	COG2770	Histidine kinase
FORC54_3636	COG2205	protein histidine kinase activity
FORC54_3638	COG0110	maltose O-acetyltransferase activity
FORC54_3644	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC54_3645	COG4605	iron ion homeostasis
FORC54_3646	COG4604	ABC transporter, ATP-binding protein
FORC54_3647	COG0789	Transcriptional regulator
FORC54_3654	COG1289	transmembrane transporter activity
FORC54_3655	COG0210	DNA helicase
FORC54_3657	COG1879	ABC-type sugar transport system periplasmic component
FORC54_3662	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FORC54_3663	COG3005	denitrification pathway
FORC54_3668	COG0513	Belongs to the DEAD box helicase family
FORC54_3670	COG1716	ATPase activity
FORC54_3670	COG5001	Diguanylate cyclase
FORC54_3675	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC54_3678	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FORC54_3679	COG0513	Belongs to the DEAD box helicase family
FORC54_3681	COG3119	arylsulfatase activity
FORC54_3683	COG0641	radical SAM
FORC54_3684	COG0641	radical SAM
FORC54_3685	COG0714	Associated with various cellular activities
FORC54_3693	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
FORC54_3695	COG0641	radical SAM
FORC54_3701	COG2814	Major facilitator Superfamily
FORC54_3709	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC54_3712	COG1132	(ABC) transporter
FORC54_3723	COG0464	growth
FORC54_3724	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC54_3724	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC54_3726	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FORC54_3735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC54_3735	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC54_3735	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FORC54_3736	COG1105	Belongs to the carbohydrate kinase PfkB family
FORC54_3737	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC54_3737	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC54_3738	COG1609	Transcriptional regulator
FORC54_3743	COG0469	pyruvate kinase activity
FORC54_3744	COG2271	Major facilitator Superfamily
FORC54_3745	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC54_3746	COG4191	Histidine kinase
FORC54_3748	COG1979	alcohol dehydrogenase
FORC54_3749	COG2207	Transcriptional regulator
FORC54_3751	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC54_3753	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC54_3756	COG0784	Response regulator, receiver
FORC54_3756	COG3437	response regulator, receiver
FORC54_3757	COG0546	phosphoglycolate phosphatase activity
FORC54_3760	COG0513	Belongs to the DEAD box helicase family
FORC54_3763	COG3038	cytochrome b561
FORC54_3765	COG2116	formate transmembrane transporter activity
FORC54_3766	COG0583	DNA-binding transcription factor activity
FORC54_3768	COG3593	DNA synthesis involved in DNA repair
FORC54_3769	COG0737	Belongs to the 5'-nucleotidase family
FORC54_3770	COG0861	Integral membrane protein TerC family
FORC54_3776	COG2267	carboxylic ester hydrolase activity
FORC54_3777	COG2067	long-chain fatty acid transport protein
FORC54_3780	COG2050	protein possibly involved in aromatic compounds catabolism
FORC54_3782	COG4533	DNA binding
FORC54_3784	COG0366	Alpha amylase catalytic
FORC54_3785	COG0583	DNA-binding transcription factor activity
FORC54_3789	COG0484	heat shock protein binding
FORC54_3792	COG5001	Diguanylate cyclase
FORC54_3792	COG1716	ATPase activity
FORC54_3793	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FORC54_3795	COG4181	ATPase activity
FORC54_3796	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FORC54_3797	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FORC54_3797	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC54_3798	COG1984	allophanate hydrolase subunit 2
FORC54_3799	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FORC54_3800	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FORC54_3802	COG3447	MASE1 domain protein
FORC54_3802	COG5002	protein histidine kinase activity
FORC54_3802	COG5001	Diguanylate cyclase
FORC54_3804	COG0583	DNA-binding transcription factor activity
FORC54_3805	COG1042	CoA-binding domain protein
FORC54_3805	COG0045	succinate-CoA ligase (ADP-forming) activity
FORC54_3805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC54_3807	COG1181	Belongs to the D-alanine--D-alanine ligase family
FORC54_3809	COG0023	Translation Initiation Factor
FORC54_3810	COG2801	Transposase and inactivated derivatives
FORC54_3812	COG3140	Belongs to the UPF0181 family
FORC54_3815	COG0745	RESPONSE REGULATOR receiver
FORC54_3817	COG3344	reverse transcriptase
FORC54_3818	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FORC54_3819	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FORC54_3822	COG3706	GGDEF domain
FORC54_3824	COG0745	RESPONSE REGULATOR receiver
FORC54_3826	COG1846	Transcriptional regulator
FORC54_3827	COG0697	spore germination
FORC54_3829	COG4149	molybdate abc transporter
FORC54_3830	COG0725	ABC transporter, periplasmic molybdate-binding protein
FORC54_3834	COG4067	protein conserved in archaea
FORC54_3834	COG0189	ligase activity
FORC54_3836	COG0602	queuosine metabolic process
FORC54_3837	COG1328	CTP reductase activity
FORC54_3848	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC54_3849	COG3118	belongs to the thioredoxin family
FORC54_3852	COG0534	Mate efflux family protein
FORC54_3856	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC54_3859	COG0848	biopolymer transport protein
FORC54_3860	COG0811	peptide transport
FORC54_3861	COG0811	peptide transport
FORC54_3867	COG2146	nitrite reductase [NAD(P)H] activity
FORC54_3868	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC54_3869	COG0840	transmembrane signaling receptor activity
FORC54_3871	COG3344	reverse transcriptase
FORC54_3874	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC54_3876	COG4251	negative regulation of phosphorylation
FORC54_3876	COG2203	Gaf domain
FORC54_3876	COG5001	Diguanylate cyclase
FORC54_3876	COG3706	GGDEF domain
FORC54_3878	COG0010	Belongs to the arginase family
FORC54_3879	COG0513	Belongs to the DEAD box helicase family
FORC54_3882	COG0523	cobalamin synthesis protein
FORC54_3884	COG2199	diguanylate cyclase activity
FORC54_3887	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC54_3887	COG2146	nitrite reductase [NAD(P)H] activity
FORC54_3888	COG1116	anion transmembrane transporter activity
FORC54_3889	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC54_3890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC54_3890	COG1116	anion transmembrane transporter activity
FORC54_3891	COG3707	response regulator
FORC54_3895	COG0243	molybdopterin cofactor binding
FORC54_3898	COG0366	Alpha amylase catalytic
FORC54_3899	COG0840	transmembrane signaling receptor activity
FORC54_3900	COG0840	transmembrane signaling receptor activity
FORC54_3903	COG2271	Major facilitator Superfamily
FORC54_3904	COG0584	glycerophosphoryl diester phosphodiesterase
FORC54_3905	COG0312	modulator of DNA gyrase
FORC54_3906	COG0312	modulator of DNA gyrase
FORC54_3908	COG3069	C4-dicarboxylate transmembrane transporter activity
FORC54_3909	COG1704	LemA family
FORC54_3910	COG0501	Belongs to the peptidase M48B family
FORC54_3914	COG3209	COG3209 Rhs family protein
FORC54_3916	COG3209	COG3209 Rhs family protein
FORC54_3919	COG3501	Rhs element vgr protein
FORC54_3931	COG0631	protein serine/threonine phosphatase activity
FORC54_3938	COG0515	serine threonine protein kinase
FORC54_3938	COG2815	serine threonine protein kinase
FORC54_3942	COG3530	Putative quorum-sensing-regulated virulence factor
FORC54_3947	COG3186	Phenylalanine-4-hydroxylase
FORC54_3948	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC54_3954	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FORC54_3956	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC54_3956	COG4191	Histidine kinase
FORC54_3957	COG3437	response regulator, receiver
FORC54_3957	COG0784	Response regulator, receiver
FORC54_3969	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FORC54_3969	COG3064	Membrane
FORC54_3969	COG1073	alpha beta
FORC54_3970	COG2994	toxin metabolic process
FORC54_3977	COG5642	Protein of unknown function (DUF2384)
FORC54_3979	COG1028	Short-chain dehydrogenase reductase Sdr
FORC54_3981	COG1024	Enoyl-CoA hydratase
FORC54_3982	COG1024	Enoyl-CoA hydratase
FORC54_3985	COG0183	Belongs to the thiolase family
FORC54_3987	COG1960	acyl-CoA dehydrogenase activity
FORC54_3988	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FORC54_3989	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FORC54_3991	COG0450	alkyl hydroperoxide reductase
FORC54_3993	COG1278	Cold shock
FORC54_3996	COG1309	transcriptional regulator
FORC54_3997	COG2130	NADP-dependent
FORC54_4001	COG2197	response regulator
FORC54_4002	COG3851	Histidine kinase
FORC54_4003	COG2271	Major facilitator Superfamily
FORC54_4004	COG1482	cell wall glycoprotein biosynthetic process
FORC54_4005	COG5001	Diguanylate cyclase
FORC54_4007	COG3036	rescue of stalled ribosome
FORC54_4008	COG1278	Cold shock
FORC54_4014	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC54_4015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC54_4016	COG0840	transmembrane signaling receptor activity
FORC54_4020	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC54_4022	COG4989	oxidoreductase activity
FORC54_4028	COG0303	'Molybdopterin
FORC54_4029	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC54_4030	COG2897	thiosulfate sulfurtransferase activity
FORC54_4034	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FORC54_4038	COG0840	transmembrane signaling receptor activity
FORC54_4040	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC54_4042	COG0109	protoheme IX farnesyltransferase activity
FORC54_4043	COG1612	heme a metabolic process
FORC54_4048	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FORC54_4049	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FORC54_4050	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FORC54_4051	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC54_4053	COG1280	lysine exporter protein (LysE YggA)
FORC54_4058	COG1846	Transcriptional regulator
FORC54_4059	COG1764	response to oxidative stress
FORC54_4062	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC54_4065	COG0697	spore germination
FORC54_4068	COG2814	Major facilitator Superfamily
FORC54_4069	COG0583	DNA-binding transcription factor activity
FORC54_4070	COG2203	Gaf domain
FORC54_4070	COG3706	GGDEF domain
FORC54_4070	COG4251	negative regulation of phosphorylation
FORC54_4070	COG5001	Diguanylate cyclase
FORC54_4071	COG0251	oxidation-reduction process
FORC54_4076	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FORC54_4078	COG1737	Transcriptional regulator
FORC54_4078	COG0837	glucose binding
FORC54_4080	COG1131	(ABC) transporter
FORC54_4081	COG0842	Transport permease protein
FORC54_4085	COG1846	Transcriptional regulator
FORC54_4089	COG0513	Belongs to the DEAD box helicase family
FORC54_4094	COG3568	Endonuclease Exonuclease Phosphatase
FORC54_4098	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC54_4110	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FORC54_4110	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FORC54_4114	COG2197	response regulator
FORC54_4115	COG3850	Histidine kinase
FORC54_4116	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC54_4118	COG0243	molybdopterin cofactor binding
FORC54_4120	COG3005	denitrification pathway
FORC54_4121	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FORC54_4122	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FORC54_4123	COG1737	Transcriptional regulator
FORC54_4124	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC54_4125	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FORC54_4126	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC54_4127	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FORC54_4129	COG1940	carbohydrate kinase activity
FORC54_4130	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC54_4134	COG0183	Belongs to the thiolase family
FORC54_4136	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC54_4137	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC54_4149	COG2827	Endonuclease containing a URI domain
FORC54_4150	COG3132	Protein of unknown function, DUF480
FORC54_4154	COG5002	protein histidine kinase activity
FORC54_4154	COG0784	Response regulator, receiver
FORC54_4154	COG2205	protein histidine kinase activity
FORC54_4159	COG0583	DNA-binding transcription factor activity
FORC54_4164	COG1522	sequence-specific DNA binding
FORC54_4165	COG0531	amino acid
FORC54_4166	COG0121	glutamine amidotransferase
FORC54_4169	COG2205	protein histidine kinase activity
FORC54_4170	COG0745	RESPONSE REGULATOR receiver
FORC54_4175	COG2239	Acts as a magnesium transporter
FORC54_4177	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FORC54_4178	COG0402	S-adenosylhomocysteine deaminase activity
FORC54_4179	COG1067	ATP-dependent peptidase activity
FORC54_4181	COG4172	Belongs to the ABC transporter superfamily
FORC54_4182	COG1505	serine-type exopeptidase activity
FORC54_4183	COG0583	DNA-binding transcription factor activity
FORC54_4184	COG1620	l-lactate permease
FORC54_4186	COG1139	Iron-sulfur cluster binding protein
FORC54_4191	COG2814	Major facilitator Superfamily
FORC54_4196	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC54_4200	COG3015	lipoprotein NlpE involved in copper resistance
FORC54_4201	COG1126	abc transporter atp-binding protein
FORC54_4202	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC54_4203	COG4215	(ABC) transporter
FORC54_4204	COG4160	amino acid transport
FORC54_4207	COG5002	protein histidine kinase activity
FORC54_4207	COG5001	Diguanylate cyclase
FORC54_4208	COG2755	lipolytic protein G-D-S-L family
FORC54_4210	COG0840	transmembrane signaling receptor activity
FORC54_4211	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC54_4217	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC54_4218	COG1028	Short-chain dehydrogenase reductase Sdr
FORC54_4219	COG1169	isochorismate synthase
FORC54_4220	COG1021	2,3-dihydroxybenzoate-AMP ligase
FORC54_4225	COG1021	2,3-dihydroxybenzoate-AMP ligase
FORC54_4227	COG4607	ABC-type enterochelin transport system periplasmic component
FORC54_4228	COG1629	transport
FORC54_4228	COG4774	siderophore transport
FORC54_4231	COG0189	ligase activity
FORC54_4231	COG4067	protein conserved in archaea
FORC54_4235	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC54_4238	COG0814	amino acid
FORC54_4239	COG0488	(ABC) transporter
FORC54_4241	COG1609	Transcriptional regulator
FORC54_4242	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC54_4245	COG0242	peptide deformylase activity
FORC54_4263	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC54_4269	COG1253	flavin adenine dinucleotide binding
FORC54_4270	COG1012	belongs to the aldehyde dehydrogenase family
FORC54_4271	COG3284	Transcriptional regulator
FORC54_4273	COG1879	ABC-type sugar transport system periplasmic component
FORC54_4274	COG0625	glutathione transferase activity
FORC54_4276	COG0384	phenazine biosynthesis protein PhzF
FORC54_4277	COG2197	response regulator
FORC54_4278	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FORC54_4279	COG0673	inositol 2-dehydrogenase activity
FORC54_4284	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FORC54_4286	COG0583	DNA-binding transcription factor activity
FORC54_4287	COG2194	sulfuric ester hydrolase activity
FORC54_4288	COG0798	PFAM Bile acid sodium symporter
FORC54_4291	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC54_4292	COG0700	Nucleoside recognition
FORC54_4293	COG3366	ferrous iron transmembrane transporter activity
FORC54_4295	COG0366	Alpha amylase catalytic
FORC54_4296	COG0800	Aldolase
FORC54_4297	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC54_4298	COG0697	spore germination
FORC54_4300	COG0583	DNA-binding transcription factor activity
FORC54_4303	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FORC54_4305	COG2985	domain, Protein
FORC54_4311	COG2272	Belongs to the type-B carboxylesterase lipase family
FORC54_4312	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC54_4313	COG0729	surface antigen
FORC54_4315	COG1917	Cupin 2, conserved barrel domain protein
FORC54_4317	COG1028	Short-chain dehydrogenase reductase Sdr
FORC54_4329	COG0668	transmembrane transport
FORC54_4338	COG0494	nUDIX hydrolase
FORC54_4339	COG1881	PFAM PEBP family protein
FORC54_4340	COG2207	Transcriptional regulator
FORC54_4341	COG3046	protein related to deoxyribodipyrimidine photolyase
FORC54_4344	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC54_4344	COG1263	PTS System
FORC54_4347	COG0454	-acetyltransferase
FORC54_4348	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC54_4353	COG1858	cytochrome C peroxidase
FORC54_4356	COG2207	Transcriptional regulator
FORC54_4357	COG2814	Major facilitator Superfamily
FORC54_4361	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FORC54_4363	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC54_4365	COG0583	DNA-binding transcription factor activity
FORC54_4369	COG0513	Belongs to the DEAD box helicase family
FORC54_4376	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC54_4378	COG1357	PFAM Pentapeptide repeats (8 copies)
FORC54_4382	COG3437	response regulator, receiver
FORC54_4384	COG0579	oxidoreductase
FORC54_4391	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FORC54_4394	COG2205	protein histidine kinase activity
FORC54_4398	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FORC54_4401	COG2199	diguanylate cyclase activity
FORC54_4408	COG2176	DNA-directed DNA polymerase activity
FORC54_4409	COG1136	(ABC) transporter
FORC54_4409	COG0577	efflux transmembrane transporter activity
FORC54_4410	COG0577	efflux transmembrane transporter activity
FORC54_4410	COG1136	(ABC) transporter
FORC54_4416	COG1120	ATPase activity
FORC54_4417	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FORC54_4423	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC54_4424	COG3716	PTS system mannose fructose sorbose family IID component
FORC54_4426	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC54_4427	COG2222	sugar isomerase
FORC54_4429	COG1349	DNA-binding transcription factor activity
FORC54_4431	COG1349	DNA-binding transcription factor activity
FORC54_4434	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FORC54_4445	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC54_4446	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC54_4450	COG0840	transmembrane signaling receptor activity
FORC54_4452	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC54_4458	COG2258	MOSC domain
FORC54_4460	COG1757	Na H antiporter
FORC54_4461	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FORC54_4462	COG0513	Belongs to the DEAD box helicase family
FORC54_4464	COG2186	Transcriptional regulator
FORC54_4466	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC54_4468	COG0246	Mannitol dehydrogenase
FORC54_4469	COG1904	glucuronate isomerase
FORC54_4470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC54_4471	COG0800	Aldolase
FORC54_4474	COG1028	Short-chain dehydrogenase reductase Sdr
FORC54_4475	COG2814	Major facilitator Superfamily
FORC54_4477	COG1902	pentaerythritol trinitrate reductase activity
FORC54_4478	COG3344	reverse transcriptase
FORC54_4482	COG0583	DNA-binding transcription factor activity
FORC54_4484	COG1902	pentaerythritol trinitrate reductase activity
FORC54_4490	COG0561	phosphatase activity
FORC54_4491	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FORC54_4492	COG3623	hexulose-6-phosphate isomerase
FORC54_4495	COG1132	(ABC) transporter
FORC54_4500	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC54_4507	COG2204	response regulator
FORC54_4517	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC54_4517	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC54_4518	COG1737	Transcriptional regulator
FORC54_4520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC54_4520	COG1263	PTS System
FORC54_4522	COG0406	alpha-ribazole phosphatase activity
FORC54_4527	COG1196	nuclear chromosome segregation
FORC54_4530	COG0745	RESPONSE REGULATOR receiver
FORC54_4530	COG3706	GGDEF domain
FORC54_4532	COG0840	transmembrane signaling receptor activity
FORC54_4533	COG2201	protein-glutamate methylesterase activity
FORC54_4534	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FORC54_4535	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC54_4536	COG0840	transmembrane signaling receptor activity
FORC54_4537	COG0835	chemotaxis
FORC54_4540	COG0745	RESPONSE REGULATOR receiver
FORC54_4542	COG1444	tRNA N-acetyltransferase activity
FORC54_p018	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC54_p019	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FORC54_p025	COG1401	restriction endodeoxyribonuclease activity
FORC54_p030	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FORC54_p033	COG1192	Involved in chromosome partitioning