locus-tag	class	description
AOT11_00020	ENOG4108IJ9	(ABC) transporter
AOT11_00025	ENOG4105D3Q	Sugar transferase
AOT11_00040	ENOG4105D75	Capsular exopolysaccharide family
AOT11_00070	ENOG4107QZV	Type I secretion membrane fusion protein
AOT11_00075	ENOG4108JJ6	Type I secretion system ATPase
AOT11_00085	ENOG41086KC	Transcriptional regulator
AOT11_00090	ENOG41086KC	Transcriptional regulator
AOT11_00100	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_00105	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AOT11_00125	ENOG4107QVM	von Willebrand factor, type A
AOT11_00140	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AOT11_00145	ENOG4105E2Z	phosphate ABC transporter (Permease
AOT11_00150	ENOG4105C8U	phosphate abc transporter
AOT11_00155	ENOG4107S17	Phosphate-binding protein
AOT11_00165	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_00190	ENOG4105C1J	atp-dependent rna helicase
AOT11_00200	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
AOT11_00205	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AOT11_00210	ENOG4108XDN	Transcriptional regulator
AOT11_00215	ENOG4107SEY	Conserved Protein
AOT11_00220	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
AOT11_00235	ENOG4106TD9	Diguanylate cyclase
AOT11_00240	ENOG4105KK7	inner membrane protein YiaW
AOT11_00245	ENOG4105EFX	secretion protein, HlyD family
AOT11_00270	ENOG4107RE3	peptidase, S41
AOT11_00275	ENOG4108MK9	spermidine N(1)-acetyltransferase
AOT11_00285	ENOG4105YE1	PilZ domain
AOT11_00300	ENOG4105D64	Mechanosensitive ion channel
AOT11_00320	ENOG4105DFG	type I secretion outer membrane protein
AOT11_00325	ENOG4107QZV	Type I secretion membrane fusion protein
AOT11_00330	ENOG4108JJA	ABC, transporter
AOT11_00340	ENOG4105H4F	exported protein
AOT11_00345	ENOG4105EQR	Transposase IS116 IS110 IS902
AOT11_00390	ENOG4105QNF	Outer membrane lipoprotein
AOT11_00430	ENOG4105CPQ	Dehydrogenase
AOT11_00435	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AOT11_00440	ENOG4105KUU	lipolytic protein G-D-S-L family
AOT11_00445	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AOT11_00455	ENOG4105E5W	Transporter
AOT11_00460	ENOG4105EXG	Transcriptional regulator
AOT11_00465	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
AOT11_00495	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AOT11_00515	ENOG4105DHT	Metal Dependent Phosphohydrolase
AOT11_00540	ENOG4105BZU	Histidine kinase
AOT11_00550	ENOG4105D05	Receptor
AOT11_00555	ENOG4107RUE	extracellular solute-binding protein family 1
AOT11_00560	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AOT11_00575	ENOG4105S8Q	sugar efflux transporter
AOT11_00585	ENOG4108YYI	Protein of unknown function (DUF2810)
AOT11_00635	ENOG4108TEM	pseudouridine methyltransferase
AOT11_00645	ENOG4105EYK	Phosphatidylglycerophosphatase B
AOT11_00660	ENOG410667J	hydrolase
AOT11_00670	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AOT11_00675	ENOG4107SJ9	decarboxylase
AOT11_00680	ENOG4108Z33	Thiol disulfide Interchange Protein
AOT11_00700	ENOG4105EXG	Transcriptional regulator
AOT11_00705	ENOG4105EMU	Dehydrogenase
AOT11_00710	ENOG4105JQN	Transcriptional regulator
AOT11_00720	ENOG4107EXC	regulatoR
AOT11_00725	ENOG4105JJR	Histidine kinase
AOT11_00730	ENOG41080IJ	Diacylglycerol kinase
AOT11_00735	ENOG4105DIJ	Phosphoethanolamine transferase
AOT11_00740	ENOG4105E0M	Sulfatase
AOT11_00755	ENOG4108K8S	endonuclease I
AOT11_00770	ENOG4105BZU	Histidine kinase
AOT11_00780	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AOT11_00815	ENOG4105E2B	Taurine dioxygenase
AOT11_00835	ENOG4105EXG	Transcriptional regulator
AOT11_00865	ENOG4105CK2	sodium dicarboxylate symporter
AOT11_00870	ENOG4105EXG	Transcriptional regulator
AOT11_00875	ENOG4105CDH	Citrulline--aspartate ligase
AOT11_00890	ENOG4105ETT	transcriptional Regulator, LysR family
AOT11_00910	ENOG4108I5U	Uridine phosphorylase
AOT11_00915	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
AOT11_00935	ENOG4105KXC	Collagenase
AOT11_00940	ENOG4108KB2	LysR family Transcriptional regulator
AOT11_00945	ENOG4107U5R	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
AOT11_00950	ENOG4105EIP	mannose-6-phosphate isomerase
AOT11_00955	ENOG4105C87	Aminotransferase class I and II
AOT11_00960	ENOG4105CI1	PTS System
AOT11_00965	ENOG4107P2S	Transcriptional regulator
AOT11_00975	ENOG4108IEG	Formate dehydrogenase Alpha subunit
AOT11_00990	ENOG4105DM4	PTS System
AOT11_00995	ENOG4105DM4	PTS System
AOT11_01005	ENOG4105CWX	Alpha-1,2-mannosidase
AOT11_01015	ENOG4105DM4	PTS System
AOT11_01020	ENOG4108YRF	PTS System
AOT11_01030	ENOG4106R3P	AraC family transcriptional regulator
AOT11_01035	ENOG4105DM4	PTS System
AOT11_01040	ENOG4105EIP	mannose-6-phosphate isomerase
AOT11_01080	ENOG4105HFT	AraC family transcriptional regulator
AOT11_01090	ENOG4105DZ0	fad dependent oxidoreductase
AOT11_01095	ENOG4108Z4U	Ferredoxin
AOT11_01105	ENOG4105CT4	transporter
AOT11_01120	ENOG4105CNT	hydrolase family 2
AOT11_01135	ENOG4107SDZ	Galactoside transport system permease protein mglC
AOT11_01140	ENOG41060NJ	transcriptional regulator
AOT11_01160	ENOG4105BZU	Histidine kinase
AOT11_01165	ENOG4105D3G	Pseudouridine synthase
AOT11_01190	ENOG4105EFX	secretion protein, HlyD family
AOT11_01200	ENOG4105UQX	Mate efflux family protein
AOT11_01205	ENOG4107RV5	Glycosyl hydrolase family 3 N-terminal domain protein
AOT11_01210	ENOG4105ECQ	AraC Family Transcriptional Regulator
AOT11_01215	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
AOT11_01230	ENOG41060NJ	transcriptional regulator
AOT11_01240	ENOG4108JQ7	(ABC) transporter
AOT11_01245	ENOG4105C3U	ABC transporter
AOT11_01250	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AOT11_01260	ENOG4105DEF	Extracellular solute-binding protein, family 5
AOT11_01270	ENOG4105ETE	Transcriptional regulator (LacI family
AOT11_01275	ENOG4108IJ9	(ABC) transporter
AOT11_01285	ENOG4105DRS	transport system, permease
AOT11_01300	ENOG41060NJ	transcriptional regulator
AOT11_01320	ENOG4105BZU	Histidine kinase
AOT11_01325	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AOT11_01330	ENOG4105DHQ	Histidine kinase
AOT11_01340	ENOG4105DUM	transcriptional regulator, lysR family
AOT11_01350	ENOG4107RAN	Peptidase, M16
AOT11_01360	ENOG4105DHT	Metal Dependent Phosphohydrolase
AOT11_01365	ENOG4105CYM	Glutathione S-transferase
AOT11_01370	ENOG4105C26	Dehydrogenase
AOT11_01380	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_01385	ENOG41083B3	HAD-superfamily subfamily IB hydrolase
AOT11_01390	ENOG4105MZU	cell filamentation protein
AOT11_01400	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
AOT11_01410	ENOG4105EW9	transcriptional regulator AsnC family
AOT11_01425	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_01430	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AOT11_01435	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
AOT11_01440	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
AOT11_01445	ENOG41061ZR	Transcriptional regulator
AOT11_01470	ENOG4108IJ9	(ABC) transporter
AOT11_01480	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AOT11_01490	ENOG4107FKK	extracellular solute-binding protein family 1
AOT11_01500	ENOG4105EG2	ABC transporter, permease
AOT11_01540	ENOG41080T7	secreted protein
AOT11_01555	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
AOT11_01560	ENOG4105D5Q	Arginine ornithine antiporter
AOT11_01565	ENOG4105CXN	decarboxylase
AOT11_01595	ENOG4107FKK	extracellular solute-binding protein family 1
AOT11_01605	ENOG4107W52	maltose operon periplasmic protein
AOT11_01610	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
AOT11_01620	ENOG4105BZU	Histidine kinase
AOT11_01625	ENOG4108K0B	C-di-gmp phosphodiesterase
AOT11_01630	ENOG4105EUB	pirin domain protein
AOT11_01640	ENOG4105NBK	UPF0345 protein
AOT11_01660	ENOG4108IG5	Transcriptional regulator
AOT11_01670	ENOG4105DN9	Na H antiporter
AOT11_01685	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AOT11_01690	ENOG4105D03	DNA-3-methyladenine glycosylase II
AOT11_01715	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
AOT11_01725	ENOG4105D6U	Sodium Glutamate Symporter
AOT11_01730	ENOG4105D6U	Sodium Glutamate Symporter
AOT11_01740	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_01745	ENOG4108VAC	response regulator
AOT11_01750	ENOG4108HRK	Histidine kinase
AOT11_01765	ENOG4105D60	lipoprotein releasing system transmembrane protein
AOT11_01770	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AOT11_01790	ENOG4105BZU	Histidine kinase
AOT11_01815	ENOG4108JQ7	(ABC) transporter
AOT11_01840	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
AOT11_01850	ENOG4108VYJ	response regulator receiver protein
AOT11_01855	ENOG4105CBS	Chea signal transduction histidine kinase
AOT11_01860	ENOG4108V3W	Chemotaxis protein, CheW
AOT11_01865	ENOG4108V3W	Chemotaxis protein, CheW
AOT11_01870	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_01875	ENOG4105BZU	Histidine kinase
AOT11_01890	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_01900	ENOG4105BZU	Histidine kinase
AOT11_01935	ENOG4105KXC	Collagenase
AOT11_01940	ENOG4105CVJ	phosphoglycerate mutase
AOT11_01955	ENOG4108EKE	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P. Is also able to take up anhydro-N-acetylmuramic acid (anhMurNAc), but cannot phosphorylate the carbon 6, probably because of the 1,6-anhydro ring (By similarity)
AOT11_01960	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AOT11_01965	ENOG4106G6Q	Transcriptional regulator
AOT11_01980	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AOT11_01985	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AOT11_02005	ENOG4105DYB	Isoaspartyl dipeptidase
AOT11_02010	ENOG4105CEE	C4-dicarboxylate transporter
AOT11_02020	ENOG4108JJA	ABC, transporter
AOT11_02035	ENOG4107QZV	Type I secretion membrane fusion protein
AOT11_02045	ENOG4105CQZ	Histidine kinase
AOT11_02050	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AOT11_02065	ENOG4105C26	Dehydrogenase
AOT11_02080	ENOG4105EW9	transcriptional regulator AsnC family
AOT11_02090	ENOG4105BZ1	(ABC) transporter
AOT11_02105	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
AOT11_02115	ENOG4108K4B	hydrolase
AOT11_02145	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AOT11_02155	ENOG4105F27	Major Facilitator
AOT11_02160	ENOG4105CHR	reductase
AOT11_02170	ENOG4105P66	Membrane
AOT11_02175	ENOG4108UHU	Aldolase
AOT11_02180	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
AOT11_02190	ENOG4105DEI	Mannitol dehydrogenase
AOT11_02195	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AOT11_02200	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
AOT11_02205	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AOT11_02210	ENOG4105C6F	GntR Family Transcriptional Regulator
AOT11_02215	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
AOT11_02220	ENOG4105C1J	atp-dependent rna helicase
AOT11_02250	ENOG4105CVR	type I restriction-modification system
AOT11_02255	ENOG4105EKX	Restriction modification system DNA (Specificity
AOT11_02260	ENOG4107SID	ATP-dependent exodnase (exonuclease v)
AOT11_02270	ENOG4105DZR	Type I site-specific deoxyribonuclease
AOT11_02275	ENOG4108RPX	mosc domain containing protein
AOT11_02305	ENOG4105VW4	glutaredoxin 3
AOT11_02320	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_02340	ENOG4107U7B	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AOT11_02345	ENOG4105E0X	reductase
AOT11_02395	ENOG4105EUZ	Beta-lactamase domain protein
AOT11_02400	ENOG41064T2	transcriptional regulator, lysR family
AOT11_02410	ENOG4105E98	transcriptional regulator DeoR family
AOT11_02420	ENOG410804X	Transcriptional regulator
AOT11_02425	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
AOT11_02430	ENOG4105E70	isomerase
AOT11_02435	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
AOT11_02445	ENOG4105F3R	pts system mannose fructose sorbose family iid
AOT11_02450	ENOG4108YTN	IIa component
AOT11_02455	ENOG4105CE4	GlcNAc 6-P deacetylase
AOT11_02460	ENOG4105D2N	Aldolase
AOT11_02475	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
AOT11_02480	ENOG4108HUF	Transporter
AOT11_02485	ENOG4105E0A	ABC, transporter
AOT11_02515	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AOT11_02520	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AOT11_02525	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AOT11_02550	ENOG4106TD9	Diguanylate cyclase
AOT11_02560	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
AOT11_02570	ENOG4105J12	Multidrug resistance protein mdtN
AOT11_02575	ENOG4105JQN	Transcriptional regulator
AOT11_02580	ENOG4105GR3	Histidine kinase
AOT11_02595	ENOG4105EUZ	Beta-lactamase domain protein
AOT11_02605	ENOG4105CQZ	Histidine kinase
AOT11_02610	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AOT11_02630	ENOG4105D5U	fad dependent oxidoreductase
AOT11_02640	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AOT11_02645	ENOG4105BZU	Histidine kinase
AOT11_02650	ENOG4108NVR	Methyl-accepting chemotaxis
AOT11_02660	ENOG4107W31	Pentapeptide repeat protein
AOT11_02670	ENOG4108M3J	Dehydrogenase
AOT11_02705	ENOG4105C1J	atp-dependent rna helicase
AOT11_02715	ENOG4108RCM	Nitroreductase
AOT11_02725	ENOG4108PZW	LysR family Transcriptional regulator
AOT11_02735	ENOG4105DP0	ferredoxin-NADP reductase
AOT11_02745	ENOG4108Q67	UPF0319 protein
AOT11_02765	ENOG4105CZQ	inner membrane transport protein YdhC
AOT11_02770	ENOG41075H3	AraC family transcriptional regulator
AOT11_02780	ENOG4105RA2	Membrane
AOT11_02785	ENOG4105CA0	peroxidase
AOT11_02795	ENOG4105VYW	UPF0251 protein
AOT11_02810	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AOT11_02815	ENOG4105I4A	GCN5-related N-acetyltransferase
AOT11_02820	ENOG4105BZU	Histidine kinase
AOT11_02825	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
AOT11_02830	ENOG4105CI1	PTS System
AOT11_02840	ENOG4108Z4X	TRANSCRIPTIONal
AOT11_02845	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
AOT11_02850	ENOG4108UQN	AraC family transcriptional regulator
AOT11_02855	ENOG4108V1U	phospholipid-binding protein
AOT11_02860	ENOG4105M6F	mutator MutT protein
AOT11_02865	ENOG4105BZU	Histidine kinase
AOT11_02895	ENOG4105D64	Mechanosensitive ion channel
AOT11_02935	ENOG4105CHR	reductase
AOT11_02940	ENOG4105M5J	Cupin 2, conserved barrel domain protein
AOT11_02955	ENOG4105CFU	surface antigen
AOT11_02960	ENOG4107RZC	phospholipase d
AOT11_02965	ENOG4105EBR	Carboxylesterase
AOT11_02980	ENOG4105Y49	secretion protein, HlyD family
AOT11_02990	ENOG4105D0C	transport protein
AOT11_02995	ENOG4105CEB	Aspartate aminotransferase
AOT11_03000	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
AOT11_03015	ENOG4105DUM	transcriptional regulator, lysR family
AOT11_03030	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
AOT11_03035	ENOG4108UHU	Aldolase
AOT11_03040	ENOG4107T9C	Alpha amylase catalytic region
AOT11_03050	ENOG41074DU	domain protein
AOT11_03055	ENOG4108P2H	Inner membrane protein YjiG
AOT11_03060	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AOT11_03085	ENOG4105DIJ	Phosphoethanolamine transferase
AOT11_03090	ENOG41064T2	transcriptional regulator, lysR family
AOT11_03100	ENOG4105EUZ	Beta-lactamase domain protein
AOT11_03125	ENOG4105D9R	oxidoreductase
AOT11_03135	ENOG4108S01	response regulator
AOT11_03140	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
AOT11_03145	ENOG4105EGI	Transcriptional regulator
AOT11_03150	ENOG4108RXX	maleylacetoacetate isomerase
AOT11_03155	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
AOT11_03160	ENOG4105BZU	Histidine kinase
AOT11_03165	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
AOT11_03170	ENOG4105C26	Dehydrogenase
AOT11_03175	ENOG4105C37	(CBS) domain
AOT11_03200	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
AOT11_03205	ENOG4105ETE	Transcriptional regulator (LacI family
AOT11_03220	ENOG4105C5H	ABC transporter
AOT11_03225	ENOG4105CIC	tryptophan-specific transport protein
AOT11_03230	ENOG4105C0F	tryptophanase EC 4.1.99.1
AOT11_03240	ENOG4108IJF	Heavy metal efflux pump, CzcA
AOT11_03260	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AOT11_03265	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AOT11_03275	ENOG4107RBR	Receptor
AOT11_03290	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
AOT11_03300	ENOG4105WQI	isochorismatase
AOT11_03305	ENOG4105Q26	Siderophore-interacting protein
AOT11_03310	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
AOT11_03315	ENOG4105E4F	Isochorismate synthase
AOT11_03320	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
AOT11_03340	ENOG4108TSE	Transferase
AOT11_03355	ENOG4105E89	ABC transporter
AOT11_03360	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_03370	ENOG4108PC0	lipolytic protein G-D-S-L family
AOT11_03375	ENOG4105BZU	Histidine kinase
AOT11_03390	ENOG4105DMR	ABC, transporter
AOT11_03395	ENOG4105GBT	ABC transporter
AOT11_03400	ENOG4106PMH	Extracellular solute-binding protein family 3
AOT11_03405	ENOG4105E5Z	arginine transporter ATP-binding subunit
AOT11_03410	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
AOT11_03425	ENOG4105CK1	PTS System
AOT11_03465	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
AOT11_03485	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
AOT11_03490	ENOG4107QR9	Iron-sulfur cluster binding protein
AOT11_03500	ENOG4105DAA	L-lactate
AOT11_03505	ENOG4105CC0	LysR family Transcriptional regulator
AOT11_03515	ENOG4108JQ5	ABC transporter
AOT11_03525	ENOG4105DAN	ATP-dependent protease
AOT11_03530	ENOG4105DZC	cytosine deaminase
AOT11_03535	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
AOT11_03540	ENOG41063ZK	Transcriptional Regulator AraC Family
AOT11_03545	ENOG4105CJW	magnesium transporter
AOT11_03585	ENOG4105EW9	transcriptional regulator AsnC family
AOT11_03605	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AOT11_03635	ENOG4105BZU	Histidine kinase
AOT11_03650	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AOT11_03675	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
AOT11_03685	ENOG4105C8I	hydrolase, family 38
AOT11_03720	ENOG4105EIP	mannose-6-phosphate isomerase
AOT11_03730	ENOG41090HJ	UPF0265 protein
AOT11_03745	ENOG41082IR	Excinuclease ABC C subunit domain protein
AOT11_03755	ENOG4108QGH	periplasmic
AOT11_03760	ENOG4105BZU	Histidine kinase
AOT11_03775	ENOG4105EW9	transcriptional regulator AsnC family
AOT11_03800	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AOT11_03805	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AOT11_03815	ENOG4105CHU	acetyl-coa acetyltransferase
AOT11_03825	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
AOT11_03855	ENOG4105BZU	Histidine kinase
AOT11_03860	ENOG4105WH1	Two component transcriptional regulator luxr family
AOT11_03880	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AOT11_03890	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AOT11_03905	ENOG4105DFG	type I secretion outer membrane protein
AOT11_03910	ENOG4105EFX	secretion protein, HlyD family
AOT11_03920	ENOG4105CH2	amidohydrolase
AOT11_03950	ENOG41066YJ	Beta-lactamase
AOT11_03955	ENOG4105CHU	acetyl-coa acetyltransferase
AOT11_03960	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AOT11_03965	ENOG4105CYC	Transferase
AOT11_03980	ENOG4105EQR	Transposase IS116 IS110 IS902
AOT11_03990	ENOG4105EQR	Transposase IS116 IS110 IS902
AOT11_04000	ENOG4105NXH	GreA GreB family elongation factor
AOT11_04040	ENOG4105C1J	atp-dependent rna helicase
AOT11_04055	ENOG410834F	Transcriptional regulator
AOT11_04085	ENOG4105EP9	oxidoreductase
AOT11_04090	ENOG4107QWP	ABC-2 type transporter
AOT11_04095	ENOG4105CJ1	ABC, transporter
AOT11_04105	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AOT11_04130	ENOG4105E2D	ec 3.2.1.52
AOT11_04140	ENOG4105M4H	endoribonuclease L-psp
AOT11_04150	ENOG4105CR8	Transcriptional regulator
AOT11_04155	ENOG4105E5M	Multidrug resistance protein D
AOT11_04165	ENOG4105VW4	glutaredoxin 3
AOT11_04170	ENOG4108SXK	Transporter Drug Metabolite Exporter family
AOT11_04175	ENOG4105BZU	Histidine kinase
AOT11_04185	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AOT11_04195	ENOG4108ZHJ	Organic hydroperoxide resistance protein
AOT11_04200	ENOG4105K56	Transcriptional regulator
AOT11_04245	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AOT11_04250	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
AOT11_04255	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
AOT11_04275	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
AOT11_04290	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AOT11_04295	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AOT11_04300	ENOG4105BZU	Histidine kinase
AOT11_04330	ENOG4105BZU	Histidine kinase
AOT11_04335	ENOG4105KHC	sulfurtransferase
AOT11_04340	ENOG4105D06	uba thif-type nad fad binding protein
AOT11_04345	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AOT11_04350	ENOG4105EUJ	GTP cyclohydrolase i
AOT11_04360	ENOG4105CMQ	Chloride channel
AOT11_04375	ENOG4107RGM	aldo keto reductase
AOT11_04390	ENOG4107YWA	deoxycytidylate deaminase
AOT11_04405	ENOG4108N3W	hemolysin secretion protein
AOT11_04410	ENOG4107VXZ	Hydrolase
AOT11_04415	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AOT11_04445	ENOG4105VEQ	Cold shock protein
AOT11_04460	ENOG4105BZU	Histidine kinase
AOT11_04470	ENOG4105EIP	mannose-6-phosphate isomerase
AOT11_04475	ENOG4105CXY	transporter
AOT11_04480	ENOG4105BZU	Histidine kinase
AOT11_04485	ENOG4108KX4	response regulator
AOT11_04490	ENOG4105CXY	transporter
AOT11_04505	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
AOT11_04510	ENOG4108WUH	Transcriptional regulator, TetR family
AOT11_04525	ENOG4105VEQ	Cold shock protein
AOT11_04530	ENOG4108JU3	Alkyl hydroperoxide reductase
AOT11_04535	ENOG4105D3R	alkyl hydroperoxide reductase
AOT11_04540	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
AOT11_04545	ENOG4108IPT	Naphthoate synthase
AOT11_04550	ENOG4107QX3	carboxylase
AOT11_04555	ENOG4105C1G	acyl-Coa dehydrogenase
AOT11_04565	ENOG4105CHU	acetyl-coa acetyltransferase
AOT11_04570	ENOG4105C26	Dehydrogenase
AOT11_04580	ENOG4105E39	Enoyl-CoA hydratase
AOT11_04585	ENOG4105E39	Enoyl-CoA hydratase
AOT11_04590	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AOT11_04595	ENOG4105CHR	reductase
AOT11_04620	ENOG4108JJA	ABC, transporter
AOT11_04640	ENOG4108RC6	RTX toxin
AOT11_04645	ENOG4105EUK	rtx toxin RtxA
AOT11_04650	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AOT11_04655	ENOG4108NVR	Methyl-accepting chemotaxis
AOT11_04660	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
AOT11_04665	ENOG4105BZJ	Electron transfer flavoprotein
AOT11_04670	ENOG4105C10	Electron transfer flavoprotein
AOT11_04675	ENOG4107QSN	dihydrolipoamide acetyltransferase
AOT11_04680	ENOG4105CPP	Dehydrogenase, E1 component
AOT11_04690	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
AOT11_04700	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AOT11_04705	ENOG4105BZU	Histidine kinase
AOT11_04715	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
AOT11_04730	ENOG4105EGI	Transcriptional regulator
AOT11_04735	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AOT11_04740	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AOT11_04745	ENOG4105MIR	Phenylalanine 4-monooxygenase
AOT11_04750	ENOG41090A4	Pterin carbinolamine dehydratase
AOT11_04755	ENOG4105BZU	Histidine kinase
AOT11_04770	ENOG4105VRT	cytoplasmic protein
AOT11_04790	ENOG4105D9P	serine threonine protein kinase
AOT11_04810	ENOG4106VK6	Flagellar motor protein
AOT11_04825	ENOG4108ZF3	Phosphatase
AOT11_04870	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AOT11_04880	ENOG4105CS6	Rhs element vgr protein
AOT11_04895	ENOG4107TV1	YD repeat protein
AOT11_04905	ENOG4107TV1	YD repeat protein
AOT11_04930	ENOG4105D0M	Protease HtpX homolog
AOT11_04935	ENOG4108V0P	LemA family
AOT11_04940	ENOG4105CEE	C4-dicarboxylate transporter
AOT11_04945	ENOG4108VAU	general secretion pathway protein G
AOT11_04960	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
AOT11_04965	ENOG4105CXY	transporter
AOT11_04980	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_04985	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_05005	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AOT11_05030	ENOG4105DG7	nitrate ABC transporter
AOT11_05035	ENOG4105D7T	ABC transporter
AOT11_05040	ENOG4107QZF	nitrite reductase NADPH large subunit
AOT11_05055	ENOG4105BZU	Histidine kinase
AOT11_05065	ENOG4105CKI	cobalamin synthesis protein
AOT11_05075	ENOG4105C1J	atp-dependent rna helicase
AOT11_05080	ENOG41088SP	formiminoglutamate hydrolase
AOT11_05095	ENOG4107Z5C	methylesterase
AOT11_05100	ENOG4105BZU	Histidine kinase
AOT11_05105	ENOG4105BZU	Histidine kinase
AOT11_05130	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_05135	ENOG4107QZF	nitrite reductase NADPH large subunit
AOT11_05140	ENOG4105WZK	nitrite reductase NADPH small subunit
AOT11_05180	ENOG4109015	Biopolymer transport protein exbD tolR
AOT11_05195	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
AOT11_05200	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_05210	ENOG4105VXR	cytoplasmic protein
AOT11_05215	ENOG4107QI1	Mate efflux family protein
AOT11_05220	ENOG4105ECQ	AraC Family Transcriptional Regulator
AOT11_05230	ENOG4105K63	Thioredoxin
AOT11_05290	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
AOT11_05295	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
AOT11_05300	ENOG4105CGF	Aromatic amino acid aminotransferase
AOT11_05305	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AOT11_05320	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AOT11_05325	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AOT11_05330	ENOG4105E0C	molybdate abc transporter
AOT11_05335	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
AOT11_05340	ENOG4108KTG	Membrane protein, drug metabolite transporter
AOT11_05345	ENOG4108ZT1	Transcriptional regulator
AOT11_05355	ENOG4108KXV	response regulator
AOT11_05365	ENOG4105BZU	Histidine kinase
AOT11_05385	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AOT11_05395	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AOT11_05410	ENOG4108ZJT	translation initiation factor, Sui1
AOT11_05430	ENOG4105CD5	CoA-binding domain protein
AOT11_05435	ENOG4105CWB	LysR family transcriptional Regulator
AOT11_05445	ENOG4105BZU	Histidine kinase
AOT11_05460	ENOG4105P4J	Allophanate hydrolase, subunit 1
AOT11_05465	ENOG4107R7A	Allophanate hydrolase subunit 2
AOT11_05470	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
AOT11_05475	ENOG4105CV6	ABC transporter, permease
AOT11_05480	ENOG4108I0Y	(ABC) transporter
AOT11_05510	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AOT11_05530	ENOG4105C5Q	Transcriptional regulator
AOT11_05535	ENOG4105CG3	alpha amylase, catalytic region
AOT11_05545	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
AOT11_05555	ENOG4105KA0	thioesterase Superfamily protein
AOT11_05570	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
AOT11_05575	ENOG4108M0H	Extracellular lipase
AOT11_05590	ENOG4108I0N	Transporter, RarD family, DMT superfamily protein
AOT11_05600	ENOG4105DU1	integral membrane protein, terc
AOT11_05605	ENOG4105CGH	5'-nucleotidase
AOT11_05610	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
AOT11_05615	ENOG4108UQ5	membrane protein YcdZ
AOT11_05620	ENOG4105DUM	transcriptional regulator, lysR family
AOT11_05625	ENOG4105TMB	Formate nitrite transporter
AOT11_05630	ENOG4108YYC	ycei family
AOT11_05635	ENOG4105DS1	cytochrome b561
AOT11_05650	ENOG4105C1J	atp-dependent rna helicase
AOT11_05655	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
AOT11_05660	ENOG4108NVR	Methyl-accepting chemotaxis
AOT11_05665	ENOG4107XGZ	Hydrolase
AOT11_05670	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AOT11_05685	ENOG4107RE1	Inosine-guanosine kinase
AOT11_05690	ENOG4105CKU	formyltetrahydrofolate synthetase
AOT11_05705	ENOG4105CF7	AraC family transcriptional regulator
AOT11_05710	ENOG4108I6A	alcohol dehydrogenase
AOT11_05715	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
AOT11_05725	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
AOT11_05730	ENOG4105CXY	transporter
AOT11_05735	ENOG4105CA9	Pyruvate kinase
AOT11_05760	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
AOT11_05765	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
AOT11_05770	ENOG4105DE4	1-phosphofructokinase
AOT11_05775	ENOG4105DM4	PTS System
AOT11_05825	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AOT11_05830	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AOT11_05840	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AOT11_05875	ENOG4105BZ1	(ABC) transporter
AOT11_05900	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
AOT11_05905	ENOG4105CC0	LysR family Transcriptional regulator
AOT11_05925	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AOT11_05945	ENOG4105F2V	VRR-NUC domain-containing protein
AOT11_05955	ENOG4105C4X	radical SAM domain protein
AOT11_05970	ENOG41064T2	transcriptional regulator, lysR family
AOT11_06000	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AOT11_06020	ENOG4105ENH	Sulfatase
AOT11_06025	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AOT11_06030	ENOG4105C1J	atp-dependent rna helicase
AOT11_06050	ENOG4107S17	Phosphate-binding protein
AOT11_06065	ENOG4105BZU	Histidine kinase
AOT11_06085	ENOG4105BZU	Histidine kinase
AOT11_06090	ENOG4105C1J	atp-dependent rna helicase
AOT11_06115	ENOG4105CUW	cytochrome C-TYPE protein
AOT11_06120	ENOG4105E6M	Sulphatase-modifying factor protein
AOT11_06145	ENOG4105BZU	Histidine kinase
AOT11_06150	ENOG4108SV3	Tmao reductase system periplasmic protein tort
AOT11_06155	ENOG4108Z5K	methylglyoxal synthase
AOT11_06160	ENOG41088T4	Helicase IV
AOT11_06165	ENOG4105EM2	membrane
AOT11_06195	ENOG4108Z6Z	Transcriptional regulator
AOT11_06200	ENOG4108IPW	abc transporter atp-binding protein
AOT11_06205	ENOG4105CM4	permease protein
AOT11_06210	ENOG4105DHS	permease protein
AOT11_06225	ENOG4108UW5	maltose o-acetyltransferase
AOT11_06230	ENOG4106YYS	transcriptional regulatory protein
AOT11_06235	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AOT11_06350	ENOG4105EYH	Exonuclease
AOT11_06355	ENOG4107RFY	SbcCD D subunit
AOT11_06365	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
AOT11_06370	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
AOT11_06380	ENOG4107R88	Chemotaxis protein (CheV)
AOT11_06390	ENOG4105ETE	Transcriptional regulator (LacI family
AOT11_06395	ENOG4108RVA	ribokinase
AOT11_06400	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
AOT11_06405	ENOG4105CNN	ABC, transporter
AOT11_06415	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
AOT11_06430	ENOG4105MSB	protein, conserved in bacteria
AOT11_06435	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
AOT11_06440	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
AOT11_06450	ENOG4105C5W	Aldolase
AOT11_06455	ENOG4106RE7	Cytochrome
AOT11_06460	ENOG4107RGH	Aldehyde dehydrogenase
AOT11_06465	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
AOT11_06475	ENOG4106CKV	Pap2 superfamily protein
AOT11_06480	ENOG41060QA	UPF0267 protein
AOT11_06490	ENOG4105FR1	rard protein
AOT11_06495	ENOG4108M1A	Chitin-binding protein
AOT11_06505	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_06515	ENOG4105MEW	serine threonine protein phosphatase
AOT11_06520	ENOG4105C44	Serine transporter
AOT11_06545	ENOG4107PU6	Membrane
AOT11_06550	ENOG4105BZS	acriflavin resistance protein
AOT11_06585	ENOG4105R8A	Heat shock protein
AOT11_06590	ENOG4105C0A	alcohol dehydrogenase
AOT11_06605	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
AOT11_06620	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
AOT11_06630	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
AOT11_06650	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AOT11_06660	ENOG4108KBJ	Inner membrane protein YkgB
AOT11_06665	ENOG4108IJ7	Glycine betaine
AOT11_06680	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
AOT11_06685	ENOG4105C26	Dehydrogenase
AOT11_06710	ENOG4105DZ1	carboxypeptidase
AOT11_06730	ENOG4105EJQ	L-serine dehydratase
AOT11_06735	ENOG4105DUX	Transporter
AOT11_06745	ENOG4105ETT	transcriptional Regulator, LysR family
AOT11_06750	ENOG4105CJP	fad dependent oxidoreductase
AOT11_06765	ENOG4107RCV	ABC transporter, permease
AOT11_06785	ENOG4108JPW	Aminotransferase
AOT11_06790	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
AOT11_06795	ENOG410874W	AraC family transcriptional regulator
AOT11_06800	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AOT11_06810	ENOG4108NVR	Methyl-accepting chemotaxis
AOT11_06825	ENOG4105PAD	Hydrolase
AOT11_06830	ENOG4105JQN	Transcriptional regulator
AOT11_06845	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
AOT11_06850	ENOG4108UKZ	OsmC family
AOT11_06855	ENOG4105E0X	reductase
AOT11_06860	ENOG4106TD9	Diguanylate cyclase
AOT11_06875	ENOG4108N3W	hemolysin secretion protein
AOT11_06880	ENOG4105BZU	Histidine kinase
AOT11_06895	ENOG4105D9N	nucleoside
AOT11_06915	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AOT11_06925	ENOG4105IH7	synthase
AOT11_06930	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
AOT11_06935	ENOG4105DR5	peptidase
AOT11_06955	ENOG4105DWD	nucleoside recognition domain protein
AOT11_06970	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_06975	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_06985	ENOG4108M6U	Universal stress protein A
AOT11_06990	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
AOT11_06995	ENOG4107R88	Chemotaxis protein (CheV)
AOT11_07005	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
AOT11_07010	ENOG41090JE	Utilization Protein
AOT11_07015	ENOG4105D4P	Coproporphyrinogen iii oxidase
AOT11_07020	ENOG4105WQ5	TonB family
AOT11_07025	ENOG41090AP	transport protein
AOT11_07030	ENOG4106GFD	transport protein
AOT11_07040	ENOG4105EHG	Permease protein
AOT11_07095	ENOG4105QVC	MOSC domain-containing protein
AOT11_07095	ENOG4105QVC	MOSC domain-containing protein
AOT11_07110	ENOG4105CKW	Inner membrane protein yedI
AOT11_07140	ENOG4105EG2	ABC transporter, permease
AOT11_07145	ENOG4105D56	permease protein
AOT11_07150	ENOG4107FKK	extracellular solute-binding protein family 1
AOT11_07160	ENOG4108IJ9	(ABC) transporter
AOT11_07165	ENOG4105D3Q	Sugar transferase
AOT11_07180	ENOG4105D75	Capsular exopolysaccharide family
AOT11_07265	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AOT11_07270	ENOG410667J	hydrolase
AOT11_07275	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_07285	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
AOT11_07295	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AOT11_07300	ENOG4105C7F	AcnD-accessory protein PrpF
AOT11_07305	ENOG4108I0Z	Aconitate hydratase
AOT11_07310	ENOG4105BZN	citrate synthase
AOT11_07315	ENOG4105CR4	methylisocitrate lyase
AOT11_07360	ENOG4105WH1	Two component transcriptional regulator luxr family
AOT11_07365	ENOG4105EJ9	Membrane
AOT11_07370	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_07375	ENOG4105BZ7	extracellular solute-binding protein family 1
AOT11_07385	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
AOT11_07395	ENOG4105E98	transcriptional regulator DeoR family
AOT11_07400	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
AOT11_07415	ENOG4105VEQ	Cold shock protein
AOT11_07420	ENOG4105BZU	Histidine kinase
AOT11_07455	ENOG4108RXX	maleylacetoacetate isomerase
AOT11_07465	ENOG4105F1J	Homogentisate 1,2-dioxygenase
AOT11_07470	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
AOT11_07475	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
AOT11_07480	ENOG4105CGH	5'-nucleotidase
AOT11_07490	ENOG41090FY	type IV pilus biogenesis stability protein PilW
AOT11_07500	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
AOT11_07505	ENOG4108VKG	metal-dependent hydrolase
AOT11_07515	ENOG4105DUM	transcriptional regulator, lysR family
AOT11_07520	ENOG4107QF7	multi-drug
AOT11_07545	ENOG4108IU2	vtamin B12-transporter permease
AOT11_07550	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
AOT11_07565	ENOG4108YZT	Adenosylcobinamide kinase
AOT11_07570	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
AOT11_07575	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
AOT11_07580	ENOG4105K4T	epimerase
AOT11_07585	ENOG4105CJB	Exodeoxyribonuclease I
AOT11_07595	ENOG41067MG	lrgb family
AOT11_07605	ENOG4105C8V	SAICAR synthetase
AOT11_07620	ENOG4105CQ7	ATP-dependent helicase
AOT11_07630	ENOG4107GZ4	SanA protein
AOT11_07635	ENOG4105C8P	)-transporter
AOT11_07640	ENOG4105BZU	Histidine kinase
AOT11_07665	ENOG4105C3M	thioredoxin reductase
AOT11_07670	ENOG4108JJ9	ABC, transporter
AOT11_07675	ENOG4108JJ8	(ABC) transporter
AOT11_07680	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AOT11_07690	ENOG4105BZU	Histidine kinase
AOT11_07690	ENOG4105BZU	Histidine kinase
AOT11_07715	ENOG4105DWU	Membrane
AOT11_07725	ENOG4105DY8	decarboxylase
AOT11_07730	ENOG4106KNT	transcriptional regulator
AOT11_07735	ENOG4107QW4	alcohol dehydrogenase
AOT11_07740	ENOG41090BQ	Glutaredoxin
AOT11_07765	ENOG4107QPN	acyl-Coa dehydrogenase
AOT11_07775	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AOT11_07790	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AOT11_07795	ENOG4105CGD	Nad-dependent epimerase dehydratase
AOT11_07805	ENOG4105C2C	drug resistance transporter, Bcr CflA
AOT11_07810	ENOG4105I08	Pseudouridine synthase
AOT11_07815	ENOG4105CFI	type iii restriction protein res subunit
AOT11_07825	ENOG4105ETX	regulatoR
AOT11_07830	ENOG4105JJR	Histidine kinase
AOT11_07835	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AOT11_07850	ENOG4105BZU	Histidine kinase
AOT11_07865	ENOG4105XZD	Fe-S protein
AOT11_07875	ENOG4105VNH	ABC transporter solute-binding protein
AOT11_07880	ENOG4105CXZ	ABC transporter, permease
AOT11_07885	ENOG4108VGW	abc transporter atp-binding protein
AOT11_07890	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
AOT11_07895	ENOG4108JUA	Transcriptional regulator
AOT11_07905	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
AOT11_07910	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AOT11_07915	ENOG4108W1A	pseudouridine synthase
AOT11_07925	ENOG4105C8J	)-transporter
AOT11_07935	ENOG4105C28	cystathionine
AOT11_07940	ENOG4108R3E	Dna-3-methyladenine glycosylase i
AOT11_07960	ENOG4105FM1	phage shock protein C
AOT11_07965	ENOG4105YYT	phage shock protein B
AOT11_07970	ENOG41087YS	Phage shock protein A
AOT11_07975	ENOG4105E51	psp operon transcriptional activator
AOT11_07980	ENOG4108J59	Extracellular solute-binding protein, family 5
AOT11_07985	ENOG4108I5W	peptide transport system, permease protein
AOT11_07990	ENOG4108EU3	peptide transport system, permease
AOT11_07995	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
AOT11_08000	ENOG4108JQ2	peptide transport system atp-binding protein
AOT11_08015	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
AOT11_08065	ENOG4105TMB	Formate nitrite transporter
AOT11_08085	ENOG4107NQ8	LysR family Transcriptional regulator
AOT11_08090	ENOG4108535	NAD dependent epimerase/dehydratase family
AOT11_08105	ENOG4105C8N	cysteinyl-tRNA synthetase
AOT11_08110	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AOT11_08120	ENOG4105D58	Diguanylate phosphodiesterase
AOT11_08130	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AOT11_08135	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AOT11_08165	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AOT11_08170	ENOG4107S6Z	Na H antiporter
AOT11_08175	ENOG4108SAU	DNA-binding protein H-ns
AOT11_08180	ENOG4107RE1	Inosine-guanosine kinase
AOT11_08195	ENOG41075W9	High frequency lysogenization protein HflD homolog
AOT11_08200	ENOG4107QTF	adenylosuccinate lyase
AOT11_08220	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AOT11_08235	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AOT11_08250	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
AOT11_08260	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AOT11_08265	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AOT11_08275	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AOT11_08280	ENOG4105D1H	recombination factor protein RarA
AOT11_08285	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
AOT11_08290	ENOG4105CNU	cell division protein FtsK
AOT11_08295	ENOG4105EW9	transcriptional regulator AsnC family
AOT11_08300	ENOG4105DCF	alanine dehydrogenase
AOT11_08310	ENOG4107R11	Transcriptional regulator
AOT11_08320	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
AOT11_08350	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
AOT11_08355	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
AOT11_08365	ENOG4105CFV	Tetratricopeptide repeat protein
AOT11_08370	ENOG4105Q4A	inner membrane protein yciS
AOT11_08375	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AOT11_08380	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AOT11_08385	ENOG4105CAT	Cytidine monophosphate kinase
AOT11_08390	ENOG4105ERU	peptidase
AOT11_08395	ENOG4105UBK	short-chain dehydrogenase reductase
AOT11_08415	ENOG4107R88	Chemotaxis protein (CheV)
AOT11_08420	ENOG4105DAG	ROK family
AOT11_08425	ENOG4105CA9	Pyruvate kinase
AOT11_08430	ENOG4108NRW	Phospholipase, patatin family
AOT11_08440	ENOG4105C8J	)-transporter
AOT11_08450	ENOG4105CI1	PTS System
AOT11_08455	ENOG4105F8V	Hydrolase, tatD family
AOT11_08460	ENOG4107QRG	dna polymerase iii
AOT11_08465	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AOT11_08470	ENOG4105HHA	aminodeoxychorismate lyase
AOT11_08480	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AOT11_08485	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AOT11_08490	ENOG4105CHR	reductase
AOT11_08495	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AOT11_08505	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AOT11_08510	ENOG4105VGS	50s ribosomal protein l32
AOT11_08515	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
AOT11_08520	ENOG4108UHJ	MAF-like protein
AOT11_08525	ENOG4105EI2	Pseudouridine synthase
AOT11_08530	ENOG4105C03	ribonuclease
AOT11_08535	ENOG4105CHH	sulfate transporter
AOT11_08545	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
AOT11_08555	ENOG4105DBI	uridine monophosphokinase
AOT11_08560	ENOG4105D1F	ATP-binding protein
AOT11_08575	ENOG4107QX9	Thiol disulfide interChange protein
AOT11_08580	ENOG4105DA4	cytochrome c-type biogenesis protein
AOT11_08585	ENOG4105DVI	reductase, NrfD
AOT11_08590	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AOT11_08595	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
AOT11_08600	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
AOT11_08615	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AOT11_08625	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AOT11_08630	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AOT11_08635	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AOT11_08660	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
AOT11_08705	ENOG4105WH1	Two component transcriptional regulator luxr family
AOT11_08710	ENOG4105CQ2	DNA polymerase
AOT11_08725	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AOT11_08730	ENOG4108W5H	UPF0263 protein
AOT11_08735	ENOG4105FE9	pseudouridine synthase
AOT11_08745	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
AOT11_08750	ENOG4105DB7	PHP domain protein
AOT11_08760	ENOG4105CRQ	synthase (Component I)
AOT11_08765	ENOG4105DDQ	anthranilate synthase
AOT11_08775	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AOT11_08780	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AOT11_08785	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AOT11_08790	ENOG4105CK2	sodium dicarboxylate symporter
AOT11_08800	ENOG4107835	probably involved in intracellular septation (By similarity)
AOT11_08805	ENOG4105NAU	thioesterase Superfamily protein
AOT11_08810	ENOG4105K9H	YciI-like protein
AOT11_08820	ENOG4105CHF	Glutathione S-transferase
AOT11_08825	ENOG4108JQ7	(ABC) transporter
AOT11_08830	ENOG4105C3U	ABC transporter
AOT11_08835	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AOT11_08840	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AOT11_08845	ENOG4107QSI	ABC, transporter
AOT11_08850	ENOG4108ZAF	Molybdopterin
AOT11_08855	ENOG4105M00	molybdopterin converting factor, subunit 1
AOT11_08870	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AOT11_08875	ENOG4105CHW	UPF0052 protein
AOT11_08885	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AOT11_08890	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AOT11_08905	ENOG4105DGN	Electron transport complex
AOT11_08910	ENOG4108R3D	Electron transport complex
AOT11_08920	ENOG4105D6A	Electron transport complex
AOT11_08930	ENOG4105DZB	Electron transport complex
AOT11_08935	ENOG4105CSM	endonuclease III
AOT11_08940	ENOG4108UYE	Lactoylglutathione lyase
AOT11_08945	ENOG4106WH9	Protein of unknown function (DUF2753)
AOT11_08950	ENOG4105EIY	sodium-type flagellar protein motY
AOT11_08960	ENOG4105D3Y	Na H antiporter
AOT11_08970	ENOG4105M2J	Glutaredoxin
AOT11_08975	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AOT11_08985	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AOT11_08995	ENOG4108EKI	Dehydrogenase
AOT11_09000	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
AOT11_09005	ENOG4105EYW	Ion transport protein
AOT11_09015	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AOT11_09020	ENOG4105DFD	Na H antiporter
AOT11_09045	ENOG4105E68	Sulfatase
AOT11_09055	ENOG4107ZYR	domain protein
AOT11_09065	ENOG4105XEP	YhcH YjgK YiaL family protein
AOT11_09070	ENOG4107RZC	phospholipase d
AOT11_09075	ENOG4105BZU	Histidine kinase
AOT11_09080	ENOG4105BZU	Histidine kinase
AOT11_09085	ENOG4105DGU	Histone deacetylase
AOT11_09090	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AOT11_09095	ENOG41069NU	Nitroreductase
AOT11_09100	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AOT11_09105	ENOG4105D07	Signal peptide peptidase, SppA
AOT11_09110	ENOG4105HDK	L-asparaginase
AOT11_09115	ENOG4105VUT	cytoplasmic protein
AOT11_09125	ENOG4105E0X	reductase
AOT11_09130	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AOT11_09135	ENOG4105DSB	aldose 1-epimerase
AOT11_09140	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_09160	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AOT11_09165	ENOG4105EPW	hflc protein
AOT11_09170	ENOG4107QJR	hflk protein
AOT11_09200	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
AOT11_09205	ENOG4108JJA	ABC, transporter
AOT11_09265	ENOG4107QTH	restriction modification system DNA specificity domain
AOT11_09280	ENOG4108F3G	Type I restriction-modification system, R subunit
AOT11_09315	ENOG4105BZU	Histidine kinase
AOT11_09330	ENOG4108MNP	Glycoprotein polysaccharide metabolism
AOT11_09335	ENOG4105C29	acyl-CoA thioesterase
AOT11_09345	ENOG4108XM1	transcriptional regulator AsnC family
AOT11_09350	ENOG4105C6T	cysteine synthase
AOT11_09365	ENOG4105BZS	acriflavin resistance protein
AOT11_09420	ENOG4107S74	Lysophospholipid transporter LplT
AOT11_09425	ENOG4105HMI	Membrane
AOT11_09435	ENOG4105CEY	Amp-dependent synthetase and ligase
AOT11_09440	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
AOT11_09445	ENOG4108IPT	Naphthoate synthase
AOT11_09450	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
AOT11_09455	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
AOT11_09460	ENOG4105E4F	Isochorismate synthase
AOT11_09465	ENOG4105CHM	Aminotransferase
AOT11_09475	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
AOT11_09480	ENOG4106IUH	DTW domain containing protein
AOT11_09490	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
AOT11_09495	ENOG4105EIN	peptidylprolyl cis-trans isomerase
AOT11_09500	ENOG4105K70	DNA-binding protein
AOT11_09505	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AOT11_09510	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AOT11_09515	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AOT11_09540	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AOT11_09545	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
AOT11_09550	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AOT11_09560	ENOG4108IJ9	(ABC) transporter
AOT11_09570	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
AOT11_09580	ENOG4105E0F	Histidine kinase
AOT11_09585	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AOT11_09590	ENOG4105CNG	UPF0061 protein
AOT11_09595	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_09630	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AOT11_09655	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
AOT11_09660	ENOG4105C84	Histidine ammonia-lyase
AOT11_09685	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AOT11_09695	ENOG4105C2D	reductase
AOT11_09700	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AOT11_09710	ENOG4105GR3	Histidine kinase
AOT11_09715	ENOG4105ETX	regulatoR
AOT11_09725	ENOG4105D9N	nucleoside
AOT11_09735	ENOG4105CVE	Lytic murein transglycosylase
AOT11_09740	ENOG4105VNG	YcgL domain-containing protein
AOT11_09745	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
AOT11_09750	ENOG4107QMS	site-determining protein
AOT11_09755	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
AOT11_09760	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
AOT11_09765	ENOG4105CEY	Amp-dependent synthetase and ligase
AOT11_09770	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AOT11_09785	ENOG41072GX	Peptidase M22 Glycoprotease
AOT11_09790	ENOG4105DVT	helicase
AOT11_09800	ENOG4105CIY	formyltetrahydrofolate deformylase
AOT11_09805	ENOG4106ZCM	YecM protein
AOT11_09810	ENOG4105C75	arginyL-tRNA synthetase
AOT11_09825	ENOG4105CE1	Ferrous iron transport protein b
AOT11_09830	ENOG4105XFK	Ferrous iron transport protein A
AOT11_09840	ENOG4105NXV	High-affinity zinc uptake system protein
AOT11_09845	ENOG4105FDK	ABC transporter
AOT11_09850	ENOG4105FAV	ABC, transporter
AOT11_09855	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AOT11_09860	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AOT11_09865	ENOG4105C7S	Dehydrogenase
AOT11_09870	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AOT11_09875	ENOG4105E33	succinate dehydrogenase
AOT11_09880	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
AOT11_09885	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
AOT11_09890	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
AOT11_09895	ENOG4105BZN	citrate synthase
AOT11_09900	ENOG4107QNR	UPF0135 protein
AOT11_09910	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AOT11_09915	ENOG4107R6U	sodium dicarboxylate symporter
AOT11_09920	ENOG4105KME	endoribonuclease L-psp
AOT11_09925	ENOG4105WWK	YheO domain protein
AOT11_09930	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
AOT11_09935	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
AOT11_09940	ENOG4105EV9	Alpha Beta Hydrolase
AOT11_09950	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
AOT11_09960	ENOG41090R7	Ferric uptake
AOT11_09970	ENOG4105CI1	PTS System
AOT11_09975	ENOG4105CE4	GlcNAc 6-P deacetylase
AOT11_09980	ENOG4105E2R	ROK family
AOT11_09985	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AOT11_09990	ENOG4105CAQ	asparagine synthetase
AOT11_10000	ENOG4105DUX	Transporter
AOT11_10010	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AOT11_10015	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AOT11_10025	ENOG4108DQ1	activator toxR
AOT11_10045	ENOG4108RE9	Phosphodiesterase
AOT11_10070	ENOG4105ECP	epimerase
AOT11_10075	ENOG4105E1F	short-chain dehydrogenase reductase
AOT11_10080	ENOG4107QR8	Thioredoxin
AOT11_10085	ENOG4107QX8	SPFH domain, Band 7 family protein
AOT11_10105	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AOT11_10110	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
AOT11_10115	ENOG4105EXN	Sulfate transport protein CysZ
AOT11_10120	ENOG4105C6T	cysteine synthase
AOT11_10125	ENOG4105KZ7	phosphocarrier protein hpr
AOT11_10130	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AOT11_10135	ENOG4105C5Y	PTS System
AOT11_10145	ENOG4105I03	Flagellin
AOT11_10150	ENOG4105I03	Flagellin
AOT11_10155	ENOG4105DTJ	flagellar hook-associated protein
AOT11_10165	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
AOT11_10170	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AOT11_10175	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AOT11_10180	ENOG4105CGA	flagellar basal-body rod protein FlgG
AOT11_10185	ENOG4108KPB	Flagellar basal-body rod protein FlgF
AOT11_10190	ENOG4105BZE	flagellar hook protein, FlgE
AOT11_10195	ENOG4105W00	Flagellar hook capping protein
AOT11_10200	ENOG4108ZC9	flagellar basal-body rod protein flgc
AOT11_10205	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
AOT11_10210	ENOG4105BZU	Histidine kinase
AOT11_10215	ENOG4107R88	Chemotaxis protein (CheV)
AOT11_10260	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AOT11_10270	ENOG41081QG	Porin Gram-negative type
AOT11_10275	ENOG4105C59	p-type ATPase
AOT11_10285	ENOG4105E2D	ec 3.2.1.52
AOT11_10290	ENOG4105MBR	gumn family
AOT11_10305	ENOG4108DG9	Smr protein MutS2
AOT11_10310	ENOG4105FE9	pseudouridine synthase
AOT11_10315	ENOG4108Z66	YbaK ebsC protein
AOT11_10320	ENOG4105CGH	5'-nucleotidase
AOT11_10325	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AOT11_10330	ENOG41063JG	Transcriptional regulator
AOT11_10335	ENOG4108YY7	Invasion gene expression up-regulator SirB
AOT11_10340	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AOT11_10345	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AOT11_10350	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AOT11_10365	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AOT11_10370	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AOT11_10375	ENOG4105C3G	gtp-binding protein
AOT11_10455	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AOT11_10465	ENOG4105C9A	Phoh family
AOT11_10475	ENOG4108JU5	Magnesium and cobalt efflux protein
AOT11_10480	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
AOT11_10485	ENOG4107PAI	alpha helical protein
AOT11_10490	ENOG4105C8T	Leucyl-tRNA synthetase
AOT11_10495	ENOG4108U2H	Rare lipoprotein B
AOT11_10500	ENOG4105DJF	DNA polymerase III, delta' subunit
AOT11_10505	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
AOT11_10510	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AOT11_10515	ENOG4105CJN	penicillin-binding protein
AOT11_10520	ENOG4105CNI	cell division protein FtsW
AOT11_10525	ENOG4105K6T	rare lipoprotein A
AOT11_10530	ENOG4105DZ1	carboxypeptidase
AOT11_10535	ENOG4108Z43	UPF0250 protein
AOT11_10545	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AOT11_10555	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AOT11_10585	ENOG4105CG3	alpha amylase, catalytic region
AOT11_10590	ENOG4105C5Y	PTS System
AOT11_10595	ENOG4105D4X	repressor
AOT11_10600	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
AOT11_10610	ENOG4108UMI	ABC transporter, permease
AOT11_10615	ENOG4105D01	(LipO)protein
AOT11_10620	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
AOT11_10625	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
AOT11_10630	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AOT11_10640	ENOG4105BZU	Histidine kinase
AOT11_10645	ENOG4105EWT	decarboxylase family
AOT11_10660	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
AOT11_10665	ENOG4105M08	Membrane
AOT11_10675	ENOG4105ETT	transcriptional Regulator, LysR family
AOT11_10680	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
AOT11_10685	ENOG4106VK6	Flagellar motor protein
AOT11_10690	ENOG4105E14	MotA TolQ exbB proton channel
AOT11_10695	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AOT11_10700	ENOG4105CTB	Polyprenyl synthetase
AOT11_10705	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AOT11_10710	ENOG4108ZAI	phosphatidylglycerophosphatase a
AOT11_10715	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AOT11_10720	ENOG4107YIM	Involved in the transcription termination process (By similarity)
AOT11_10725	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AOT11_10740	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AOT11_10750	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AOT11_10755	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AOT11_10760	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
AOT11_10770	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
AOT11_10775	ENOG4105C7N	Xanthine uracil vitamin C permease
AOT11_10780	ENOG4105CIN	aminoacyl-histidine dipeptidase
AOT11_10805	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AOT11_10810	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
AOT11_10815	ENOG4108Z6B	deaminase
AOT11_10820	ENOG4105CC0	LysR family Transcriptional regulator
AOT11_10830	ENOG4105C4W	S-formylglutathione hydrolase
AOT11_10835	ENOG4105CFC	Transporter
AOT11_10865	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AOT11_10870	ENOG4105CFG	Acts as a chaperone (By similarity)
AOT11_10915	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AOT11_10920	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AOT11_10925	ENOG4105VDB	UPF0125 protein
AOT11_10930	ENOG4108Z1B	Cyclase dehydrase
AOT11_10935	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AOT11_10980	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AOT11_10990	ENOG4105C94	Transporter
AOT11_11000	ENOG4107RSM	transcriptional regulator
AOT11_11005	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AOT11_11010	ENOG4105BZG	amino acid carrier protein
AOT11_11015	ENOG4106HK8	GPR1 FUN34 yaaH family protein
AOT11_11030	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AOT11_11045	ENOG410620I	Diguanylate cyclase
AOT11_11055	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AOT11_11060	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AOT11_11065	ENOG4105N21	Membrane
AOT11_11070	ENOG4105CUT	histidyl-tRNA synthetase
AOT11_11075	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AOT11_11085	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AOT11_11090	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AOT11_11095	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AOT11_11100	ENOG4105WVQ	Fe-S assembly protein IscX
AOT11_11105	ENOG4108ZIT	Ferredoxin, 2FE-2S
AOT11_11115	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
AOT11_11120	ENOG4108Z4V	iron-sulfur cluster assembly
AOT11_11125	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
AOT11_11130	ENOG4105C3J	Cysteine desulfurase
AOT11_11135	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
AOT11_11140	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
AOT11_11145	ENOG4105ECY	inositol monophosphatase
AOT11_11150	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AOT11_11155	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AOT11_11160	ENOG4105VIE	preprotein translocase, subunit YajC
AOT11_11165	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AOT11_11180	ENOG4105W87	Cbs domain
AOT11_11185	ENOG4108I9X	Isocitrate lyase
AOT11_11190	ENOG4107QP3	malate synthase g
AOT11_11195	ENOG4105C5Q	Transcriptional regulator
AOT11_11200	ENOG4105D3R	alkyl hydroperoxide reductase
AOT11_11205	ENOG4106N3A	copper homeostasis protein cutc
AOT11_11210	ENOG4105CSR	polyphosphate kinase 2
AOT11_11220	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AOT11_11225	ENOG4105E2Z	phosphate ABC transporter (Permease
AOT11_11230	ENOG4105C8U	phosphate abc transporter
AOT11_11240	ENOG4105C9X	ppx gppa phosphatase
AOT11_11250	ENOG4105BZU	Histidine kinase
AOT11_11255	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AOT11_11260	ENOG4105DH7	May be involved in recombination (By similarity)
AOT11_11265	ENOG4105CFP	Peptidase U32
AOT11_11270	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AOT11_11310	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AOT11_11315	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AOT11_11320	ENOG4105C34	Pseudouridine synthase
AOT11_11325	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AOT11_11330	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
AOT11_11345	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
AOT11_11350	ENOG4107SC1	transglycosylase
AOT11_11355	ENOG4105C5H	ABC transporter
AOT11_11365	ENOG4105DR5	peptidase
AOT11_11370	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
AOT11_11375	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AOT11_11380	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
AOT11_11410	ENOG4108HRK	Histidine kinase
AOT11_11415	ENOG4108NEV	two component transcriptional regulator, LytTR family
AOT11_11420	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AOT11_11425	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
AOT11_11430	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AOT11_11440	ENOG4105DTN	riboflavin biosynthesis protein ribF
AOT11_11445	ENOG4105CJR	Integral membrane protein (MviN
AOT11_11450	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AOT11_11455	ENOG41080HT	Transcriptional regulator, arsr family
AOT11_11460	ENOG41063Z6	transcriptional regulator, lysR family
AOT11_11545	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AOT11_11565	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AOT11_11575	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AOT11_11580	ENOG4105HF0	Membrane
AOT11_11585	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
AOT11_11590	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AOT11_11595	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
AOT11_11605	ENOG4105CPC	Aldo Keto reductase
AOT11_11630	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AOT11_11635	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AOT11_11640	ENOG4105T95	Thiol disulfide interChange protein
AOT11_11645	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AOT11_11650	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
AOT11_11655	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
AOT11_11660	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
AOT11_11665	ENOG4105C1J	atp-dependent rna helicase
AOT11_11675	ENOG4105BZG	amino acid carrier protein
AOT11_11690	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AOT11_11695	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
AOT11_11700	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
AOT11_11705	ENOG4105D98	threonine synthase
AOT11_11710	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AOT11_11725	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AOT11_11735	ENOG41065U4	response regulator
AOT11_11745	ENOG4105BZU	Histidine kinase
AOT11_11755	ENOG4105N5T	Radical SAM Protein
AOT11_11770	ENOG4105CBC	glutamate synthase
AOT11_11775	ENOG4105BZ8	glutamate synthase
AOT11_11790	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AOT11_11795	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
AOT11_11800	ENOG4105EN6	Membrane
AOT11_11805	ENOG4105VP0	transcriptional regulator, lysR family
AOT11_11810	ENOG4105EJ9	Membrane
AOT11_11825	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AOT11_11835	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AOT11_11840	ENOG4105M6F	mutator MutT protein
AOT11_11855	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AOT11_11860	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AOT11_11865	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AOT11_11870	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
AOT11_11880	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AOT11_11890	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AOT11_11900	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
AOT11_11905	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AOT11_11910	ENOG4105CJN	penicillin-binding protein
AOT11_11915	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AOT11_11920	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AOT11_11925	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
AOT11_11935	ENOG41082RQ	UPF0102 protein
AOT11_11940	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
AOT11_11945	ENOG4105W4M	Transport-associated protein
AOT11_11950	ENOG4105KB2	stringent starvation protein b
AOT11_11955	ENOG4107MKT	Stringent starvation protein a
AOT11_11960	ENOG4105EIX	cytochrome c1
AOT11_11965	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AOT11_11970	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AOT11_11975	ENOG4108UJD	30S ribosomal protein S9
AOT11_11980	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AOT11_11985	ENOG4105D6Z	AFG1 family ATPase
AOT11_11990	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
AOT11_11995	ENOG4105C0H	protease
AOT11_12000	ENOG4105C0H	protease
AOT11_12005	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AOT11_12010	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AOT11_12015	ENOG4105IPS	esterase
AOT11_12020	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
AOT11_12025	ENOG4108SX3	cytoplasmic protein
AOT11_12030	ENOG41087AY	ADP-Ribose pyrophosphatase
AOT11_12035	ENOG4105DFG	type I secretion outer membrane protein
AOT11_12040	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
AOT11_12060	ENOG4105I7R	Adenylate cyclase
AOT11_12065	ENOG4107IX6	phosphate transport regulator
AOT11_12070	ENOG4105CJ3	phosphate transporter
AOT11_12075	ENOG4106MWK	domain protein
AOT11_12090	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AOT11_12095	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AOT11_12100	ENOG4107ZVW	dihydroneopterin aldolase
AOT11_12105	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
AOT11_12110	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
AOT11_12115	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AOT11_12120	ENOG4105VCC	30S ribosomal protein S21
AOT11_12125	ENOG4105KTH	gatB Yqey
AOT11_12130	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AOT11_12135	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AOT11_12150	ENOG4105CAF	HipA N-terminal domain protein
AOT11_12165	ENOG4105CH5	extracellular solute-binding protein, family 7
AOT11_12170	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AOT11_12175	ENOG410804X	Transcriptional regulator
AOT11_12180	ENOG4105CA9	Pyruvate kinase
AOT11_12190	ENOG4105BZU	Histidine kinase
AOT11_12195	ENOG4108ZP8	Acetolactate synthase small subunit
AOT11_12200	ENOG4105C7K	acetolactate synthase
AOT11_12205	ENOG4108IQE	Amp-dependent synthetase and ligase
AOT11_12210	ENOG41064T2	transcriptional regulator, lysR family
AOT11_12230	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AOT11_12240	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AOT11_12255	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
AOT11_12260	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
AOT11_12265	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AOT11_12275	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AOT11_12280	ENOG4105NWN	ApaG protein
AOT11_12285	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
AOT11_12295	ENOG4107XM3	UPF0442 protein
AOT11_12300	ENOG4105DWK	Membrane
AOT11_12305	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AOT11_12310	ENOG4105K46	50S ribosomal protein l27
AOT11_12315	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AOT11_12320	ENOG4105EAH	synthase
AOT11_12330	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
AOT11_12345	ENOG41081QV	Universal stress protein
AOT11_12355	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
AOT11_12360	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AOT11_12365	ENOG4105VFK	BolA family
AOT11_12375	ENOG4105E3I	toluene tolerance
AOT11_12380	ENOG4107PE3	Mammalian cell entry related domain protein
AOT11_12385	ENOG4105CY3	ABC transporter, permease
AOT11_12390	ENOG4105DHJ	ABC, transporter
AOT11_12400	ENOG4105C2X	Arabinose 5-phosphate isomerase
AOT11_12405	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
AOT11_12415	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
AOT11_12420	ENOG4108IUZ	ABC transporter
AOT11_12425	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AOT11_12430	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
AOT11_12435	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
AOT11_12445	ENOG41080Z8	PHOSPHOCARRIER protein
AOT11_12450	ENOG4105CJW	magnesium transporter
AOT11_12455	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
AOT11_12465	ENOG4107T0D	ABC, transporter
AOT11_12470	ENOG4106SMU	thiamine transporter membrane protein
AOT11_12475	ENOG4105DP9	ABC transporter
AOT11_12480	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
AOT11_12485	ENOG4105DFU	Cell wall formation (By similarity)
AOT11_12490	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AOT11_12495	ENOG4105F0N	pyrophosphate phospho-hydrolase
AOT11_12505	ENOG41066HZ	AIG2-like family
AOT11_12510	ENOG4105MA0	exported protein
AOT11_12515	ENOG4105CFU	surface antigen
AOT11_12520	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AOT11_12530	ENOG4108UUE	Transcriptional regulator
AOT11_12545	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AOT11_12565	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
AOT11_12580	ENOG4105C11	sulfate adenylyltransferase), subunit 2
AOT11_12585	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AOT11_12590	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
AOT11_12600	ENOG4107YB6	acetyltransferase, (GNAT) family
AOT11_12610	ENOG4108UBT	opacity-associated protein
AOT11_12615	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AOT11_12625	ENOG4108ZT0	50S ribosomal protein l17
AOT11_12630	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AOT11_12635	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AOT11_12640	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AOT11_12645	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AOT11_12655	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AOT11_12660	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AOT11_12665	ENOG4105VPB	50S ribosomal protein L30
AOT11_12670	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AOT11_12675	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AOT11_12680	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AOT11_12685	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AOT11_12690	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AOT11_12695	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AOT11_12700	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AOT11_12705	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AOT11_12710	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AOT11_12715	ENOG41083MP	50s ribosomal protein l29
AOT11_12720	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AOT11_12725	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AOT11_12730	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AOT11_12735	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AOT11_12740	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AOT11_12745	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AOT11_12750	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AOT11_12760	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AOT11_12775	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AOT11_12790	ENOG4105ESV	Glycosyl transferase, family 4
AOT11_12795	ENOG410600T	transposase
AOT11_12830	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AOT11_12835	ENOG4105D4A	Cell wall formation (By similarity)
AOT11_12840	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
AOT11_12850	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
AOT11_12855	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AOT11_12875	ENOG4105DAY	polysaccharide export protein
AOT11_12895	ENOG4108Y9B	(LipO)protein
AOT11_12905	ENOG4105E3R	(LipO)protein
AOT11_12910	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
AOT11_12915	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
AOT11_12920	ENOG4105XA0	heptosyltransferase ii
AOT11_12925	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
AOT11_12965	ENOG4105F0R	Cytidylyltransferase
AOT11_12970	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AOT11_12975	ENOG4105C5E	polysaccharide biosynthesis protein
AOT11_13005	ENOG4105E68	Sulfatase
AOT11_13015	ENOG41080IJ	Diacylglycerol kinase
AOT11_13020	ENOG4105DKP	glycosyl transferase, family 9
AOT11_13025	ENOG4106WTF	Glycosyl transferase, family 2
AOT11_13030	ENOG4105M5K	heptosyltransferase
AOT11_13035	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AOT11_13045	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AOT11_13055	ENOG4105W0E	50S ribosomal protein L33
AOT11_13060	ENOG4105KDC	50s ribosomal protein l28
AOT11_13070	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_13075	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AOT11_13080	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
AOT11_13085	ENOG4105D1S	lipid A biosynthesis
AOT11_13090	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AOT11_13095	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AOT11_13100	ENOG4105DSJ	YicC domain protein
AOT11_13115	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AOT11_13135	ENOG4107QRA	Extracellular solute-binding protein, family 5
AOT11_13140	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
AOT11_13145	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
AOT11_13150	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AOT11_13170	ENOG4109015	Biopolymer transport protein exbD tolR
AOT11_13185	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AOT11_13190	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AOT11_13195	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AOT11_13200	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
AOT11_13205	ENOG4105CB5	ATP-dependent DNA helicase recG
AOT11_13210	ENOG4105C2W	permease
AOT11_13215	ENOG4105E0F	Histidine kinase
AOT11_13220	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AOT11_13225	ENOG4108RRZ	Transcription elongation factor GreB
AOT11_13230	ENOG4105BZM	domain protein
AOT11_13245	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AOT11_13250	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
AOT11_13255	ENOG4107RK2	ADP-ribose diphosphatase NudE
AOT11_13260	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
AOT11_13265	ENOG4105PIC	general secretion pathway protein N
AOT11_13270	ENOG4105U1E	general secretion pathway protein M
AOT11_13275	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
AOT11_13280	ENOG4108RTD	type II secretion system protein K
AOT11_13285	ENOG4108WWZ	General secretion pathway protein J
AOT11_13290	ENOG4105X5Z	General secretion pathway protein I
AOT11_13295	ENOG4105VWV	general secretion pathway protein h
AOT11_13300	ENOG4108VAU	general secretion pathway protein G
AOT11_13305	ENOG4105D7Q	type ii secretion system
AOT11_13310	ENOG4107QHF	type ii secretion system protein e
AOT11_13320	ENOG4108XKW	General secretion pathway protein C
AOT11_13325	ENOG4105VEJ	Heat shock protein
AOT11_13330	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AOT11_13335	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
AOT11_13345	ENOG4105SUU	thioesterase domain
AOT11_13350	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AOT11_13375	ENOG4105C5F	glutamine synthetase
AOT11_13385	ENOG4105CUX	Signal transduction histidine kinase
AOT11_13390	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AOT11_13395	ENOG4105BZU	Histidine kinase
AOT11_13400	ENOG4105D4P	Coproporphyrinogen iii oxidase
AOT11_13405	ENOG4105XCT	Protein of unknown function (DUF2489)
AOT11_13410	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
AOT11_13420	ENOG4106RE7	Cytochrome
AOT11_13430	ENOG4105C2M	dna polymerase I
AOT11_13435	ENOG4105D52	delta-aminolevulinic acid dehydratase
AOT11_13440	ENOG4105F8V	Hydrolase, tatD family
AOT11_13445	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AOT11_13450	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AOT11_13460	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AOT11_13465	ENOG4105JC1	sterol-binding domain protein
AOT11_13470	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AOT11_13475	ENOG4105CGY	Dna recombination protein
AOT11_13545	ENOG4107QK7	reductase
AOT11_13555	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
AOT11_13565	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AOT11_13570	ENOG4105K63	Thioredoxin
AOT11_13575	ENOG4105C1J	atp-dependent rna helicase
AOT11_13580	ENOG4105C9X	ppx gppa phosphatase
AOT11_13585	ENOG4105EX9	Membrane
AOT11_13595	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AOT11_13600	ENOG4105FR1	rard protein
AOT11_13615	ENOG4105C4R	Atp-dependent dna helicase
AOT11_13625	ENOG4105E18	UPF0276 protein
AOT11_13645	ENOG4105C2C	drug resistance transporter, Bcr CflA
AOT11_13655	ENOG4105DC7	peptidase M24
AOT11_13655	ENOG4105DC7	peptidase M24
AOT11_13660	ENOG4105D41	biosynthesis protein thiH
AOT11_13665	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AOT11_13675	ENOG4105D06	uba thif-type nad fad binding protein
AOT11_13680	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AOT11_13685	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AOT11_13690	ENOG4105WMR	Protein CrcB homolog
AOT11_13695	ENOG4107R16	Multicopper oxidase
AOT11_13745	ENOG4107R08	Integrase
AOT11_13795	ENOG4108RR8	protoporphyrinogen oxidase
AOT11_13800	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AOT11_13805	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AOT11_13810	ENOG4108DP9	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
AOT11_13820	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
AOT11_13835	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
AOT11_13850	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
AOT11_13865	ENOG4105JKW	Valine--pyruvate aminotransferase
AOT11_13870	ENOG4105BZU	Histidine kinase
AOT11_13875	ENOG4108ZNX	Heat shock protein
AOT11_13880	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AOT11_13885	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AOT11_13890	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AOT11_13895	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AOT11_13900	ENOG4105EAB	amino acid AbC transporter
AOT11_13905	ENOG4105E5Q	amino acid AbC transporter
AOT11_13910	ENOG4105CDA	abc transporter atp-binding protein
AOT11_13915	ENOG4105VG0	50S ribosomal protein l34
AOT11_13920	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AOT11_13930	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AOT11_13935	ENOG4105QTB	Flavodoxin
AOT11_13945	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AOT11_13950	ENOG4107QJE	Chromosome Partitioning Protein
AOT11_13955	ENOG4105FA0	parb-like partition protein
AOT11_13960	ENOG410684E	atp synthase
AOT11_13965	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
AOT11_13970	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AOT11_13975	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AOT11_13980	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AOT11_13985	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AOT11_13990	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AOT11_13995	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AOT11_14000	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AOT11_14005	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AOT11_14010	ENOG4105EAD	ABC transporter
AOT11_14015	ENOG4105F87	Dehydratase
AOT11_14020	ENOG4105CZQ	inner membrane transport protein YdhC
AOT11_14025	ENOG4105F52	Transcriptional regulator
AOT11_14030	ENOG4105C7B	Threonine dehydratase
AOT11_14040	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AOT11_14045	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
AOT11_14055	ENOG4105C0P	Mg chelatase subunit ChlI
AOT11_14065	ENOG4106HNH	Acyl-transferase
AOT11_14070	ENOG4108Z33	Thiol disulfide Interchange Protein
AOT11_14075	ENOG4105E27	serine threonine protein kinase
AOT11_14085	ENOG4105PC1	Conserved Protein
AOT11_14090	ENOG4108N23	SpoOM-related protein
AOT11_14095	ENOG4108UT2	hemolysin iii
AOT11_14100	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AOT11_14105	ENOG4105C1A	potassium transporter peripheral membrane
AOT11_14120	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AOT11_14130	ENOG4105C79	DNA protecting protein DprA
AOT11_14135	ENOG4108RPN	Protein smg homolog
AOT11_14140	ENOG4108WI1	Dna topoisomerase
AOT11_14150	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AOT11_14155	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AOT11_14160	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AOT11_14175	ENOG4105SG3	Protein of unknown function (DUF1488)
AOT11_14180	ENOG4108Z0R	Transferase
AOT11_14215	ENOG4105EMY	transcriptional regulator
AOT11_14220	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AOT11_14225	ENOG4105W0Z	cytoplasmic protein
AOT11_14230	ENOG4105BZS	acriflavin resistance protein
AOT11_14235	ENOG410624X	efflux transporter, rnd family, mfp subunit
AOT11_14240	ENOG4105Y7M	Transcriptional regulator, TetR family
AOT11_14245	ENOG4105C4R	Atp-dependent dna helicase
AOT11_14250	ENOG4105MPD	Cytochrome
AOT11_14280	ENOG4108JQ6	ABC transporter
AOT11_14285	ENOG4107QSI	ABC, transporter
AOT11_14290	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AOT11_14295	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AOT11_14330	ENOG4108DT4	serine threonine protein kinase
AOT11_14340	ENOG4108VYJ	response regulator receiver protein
AOT11_14345	ENOG4105DIQ	Transcriptional regulator
AOT11_14350	ENOG4105C01	Dihydroxy-acid dehydratase
AOT11_14355	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
AOT11_14360	ENOG4105C6Z	Gluconate
AOT11_14365	ENOG4108UHU	Aldolase
AOT11_14375	ENOG4105DC8	reductase
AOT11_14380	ENOG4105D6S	protein involved in catabolism of external DNA
AOT11_14385	ENOG4105DGW	oligopeptidase A
AOT11_14390	ENOG4108VVK	transcriptional Regulator, AsnC
AOT11_14395	ENOG4105BZU	Histidine kinase
AOT11_14410	ENOG4105EMK	carboxylate amino acid amine transporter
AOT11_14415	ENOG4108M6U	Universal stress protein A
AOT11_14420	ENOG41090A1	ferritin
AOT11_14425	ENOG4108V6B	universal stress protein B
AOT11_14430	ENOG4105CBX	hi0933 family
AOT11_14440	ENOG4105ECF	c-methyltransferase
AOT11_14445	ENOG41076E6	Uroporphyrinogen-III Synthase
AOT11_14450	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AOT11_14455	ENOG4107T0K	Adenylate cyclase
AOT11_14460	ENOG4105XQ6	frataxin-like protein
AOT11_14470	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AOT11_14475	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AOT11_14485	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AOT11_14490	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
AOT11_14495	ENOG4105BZU	Histidine kinase
AOT11_14500	ENOG4106IUH	DTW domain containing protein
AOT11_14515	ENOG4105DQF	Hydrolase
AOT11_14520	ENOG4108EUD	Lysophospholipase
AOT11_14525	ENOG410829K	Lysine exporter protein (Lyse ygga)
AOT11_14530	ENOG4105D58	Diguanylate phosphodiesterase
AOT11_14535	ENOG41082YX	Transcriptional regulator, arsr family
AOT11_14540	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AOT11_14580	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
AOT11_14590	ENOG4106H78	methyltransferase
AOT11_14595	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AOT11_14600	ENOG4105CAK	Cell division ATP-binding protein ftsE
AOT11_14605	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
AOT11_14610	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AOT11_14615	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
AOT11_14620	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
AOT11_14625	ENOG4105X6C	Flagellar basal body-associated protein FliL
AOT11_14635	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
AOT11_14645	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AOT11_14655	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
AOT11_14670	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
AOT11_14685	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AOT11_14765	ENOG4105JIM	Phosphatidylserine synthase
AOT11_14780	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AOT11_14785	ENOG4105CS9	pantothenic acid kinase
AOT11_14810	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AOT11_14815	ENOG4105PM1	preprotein translocase subunit SecE
AOT11_14820	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AOT11_14825	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AOT11_14830	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AOT11_14835	ENOG4108VZM	50s ribosomal protein L10
AOT11_14840	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AOT11_14845	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AOT11_14850	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AOT11_14855	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
AOT11_14860	ENOG4105E09	nadh pyrophosphatase
AOT11_14875	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AOT11_14885	ENOG4108RG0	uracil-dna glycosylase
AOT11_14895	ENOG4105R2J	Conserved Protein
AOT11_14915	ENOG4105C12	Phosphoribosylglycinamide synthetase
AOT11_14920	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AOT11_14925	ENOG4105W1Y	Transcriptional regulator
AOT11_14930	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_14935	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
AOT11_14940	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AOT11_14950	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AOT11_14955	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AOT11_14960	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AOT11_14980	ENOG4105D8G	Major Facilitator superfamily
AOT11_14985	ENOG4105BZU	Histidine kinase
AOT11_15000	ENOG4107QN1	sodium solute
AOT11_15010	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
AOT11_15025	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
AOT11_15030	ENOG4108IJ0	Aspartate ammonia-lyase
AOT11_15040	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AOT11_15045	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AOT11_15050	ENOG4105E0F	Histidine kinase
AOT11_15055	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AOT11_15060	ENOG4108SPG	Periplasmic Protein
AOT11_15065	ENOG41076HS	cation diffusion facilitator family transporter
AOT11_15070	ENOG4105CTQ	phosphohexokinase
AOT11_15075	ENOG4107QI1	Mate efflux family protein
AOT11_15080	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AOT11_15085	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AOT11_15095	ENOG4105KT7	mgtC SapB transporter
AOT11_15100	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
AOT11_15105	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AOT11_15125	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
AOT11_15140	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
AOT11_15150	ENOG41062JF	Transcriptional regulator
AOT11_15160	ENOG41063SB	peptidase
AOT11_15165	ENOG4105D7W	serine acetyltransferase
AOT11_15170	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AOT11_15175	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
AOT11_15180	ENOG4107YZP	Rhodanese domain protein
AOT11_15195	ENOG4105C8P	)-transporter
AOT11_15200	ENOG4105DJ4	phosphatidylserine decarboxylase
AOT11_15205	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AOT11_15210	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AOT11_15255	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AOT11_15260	ENOG4105K8N	protein family UPF0079, ATPase
AOT11_15265	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AOT11_15275	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AOT11_15280	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
AOT11_15285	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AOT11_15290	ENOG4107QJR	hflk protein
AOT11_15295	ENOG4105EPW	hflc protein
AOT11_15310	ENOG4108UV7	flagellar protein motX
AOT11_15315	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
AOT11_15320	ENOG4105KPV	Transcriptional regulator
AOT11_15325	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AOT11_15330	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AOT11_15335	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AOT11_15360	ENOG4105DDQ	anthranilate synthase
AOT11_15385	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
AOT11_15390	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
AOT11_15395	ENOG4105YP7	UPF0270 protein
AOT11_15400	ENOG4105DNZ	Alpha Beta Hydrolase
AOT11_15410	ENOG4105C5H	ABC transporter
AOT11_15415	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
AOT11_15430	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AOT11_15435	ENOG4105D44	asparaginase
AOT11_15440	ENOG41069P5	Protein slyX homolog
AOT11_15450	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AOT11_15455	ENOG4105WWK	YheO domain protein
AOT11_15465	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
AOT11_15475	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AOT11_15480	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AOT11_15490	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AOT11_15495	ENOG4105W53	bacterioferritin-associated ferredoxin
AOT11_15500	ENOG4108UQY	Iron-storage protein
AOT11_15505	ENOG4105CMR	udp-glucose 4-epimerase
AOT11_15510	ENOG4105CP7	Triose-phosphate isomerase
AOT11_15535	ENOG4105CBT	Fructose-1,6-bisphosphatase
AOT11_15540	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
AOT11_15545	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AOT11_15550	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
AOT11_15555	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
AOT11_15560	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AOT11_15570	ENOG4105ETE	Transcriptional regulator (LacI family
AOT11_15575	ENOG4105C25	Primosomal protein n'
AOT11_15580	ENOG4105VFB	Binds the 23S rRNA (By similarity)
AOT11_15585	ENOG4105C6K	Malic enzyme
AOT11_15590	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
AOT11_15595	ENOG4105C28	cystathionine
AOT11_15600	ENOG4105CFH	Aspartokinase
AOT11_15605	ENOG4105SYT	Methylenetetrahydrofolate reductase
AOT11_15630	ENOG4105CAS	nag kinase
AOT11_15635	ENOG4105CDH	Citrulline--aspartate ligase
AOT11_15640	ENOG4105CH7	arginosuccinase
AOT11_15650	ENOG4105C5Q	Transcriptional regulator
AOT11_15655	ENOG4108JQC	penicillin-binding protein 1A
AOT11_15680	ENOG4105E4G	Type IV pilus
AOT11_15685	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AOT11_15690	ENOG4105D49	3-dehydroquinate synthase
AOT11_15700	ENOG4105DFE	Dna adenine methylase
AOT11_15705	ENOG4105DJV	ribulose-phosphate 3-epimerase
AOT11_15710	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AOT11_15715	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
AOT11_15720	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AOT11_15725	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AOT11_15735	ENOG4105CDU	Replicative dna helicase
AOT11_15750	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
AOT11_15755	ENOG4107QP8	phosphohexose isomerase
AOT11_15765	ENOG4105MYN	Zinc uptake regulation protein
AOT11_15770	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AOT11_15790	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AOT11_15800	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AOT11_15880	ENOG4105BZU	Histidine kinase
AOT11_15885	ENOG4105EEQ	Na H antiporter
AOT11_15895	ENOG4105CFH	Aspartokinase
AOT11_15900	ENOG4105C5R	Aminotransferase
AOT11_15910	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AOT11_15915	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AOT11_15920	ENOG41086KC	Transcriptional regulator
AOT11_15925	ENOG4108UUM	single-stranded DNA-binding protein
AOT11_15930	ENOG41062P1	Diguanylate cyclase phosphodiesterase
AOT11_15950	ENOG4105E4G	Type IV pilus
AOT11_15965	ENOG4107QHF	type ii secretion system protein e
AOT11_15970	ENOG4105D7Q	type ii secretion system
AOT11_15980	ENOG4105X0D	Fimbrial protein
AOT11_16015	ENOG4105DFF	Rod shape-determining protein mreb
AOT11_16020	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AOT11_16025	ENOG4105VQ7	Rod shape-determining protein MreD
AOT11_16030	ENOG4108Z03	MAF-like protein
AOT11_16035	ENOG4105C03	ribonuclease
AOT11_16040	ENOG4105QD6	exported protein
AOT11_16050	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
AOT11_16055	ENOG4108IAB	Phoh family
AOT11_16065	ENOG4105D3G	Pseudouridine synthase
AOT11_16070	ENOG4105C5I	Dehydrogenase
AOT11_16075	ENOG4105KME	endoribonuclease L-psp
AOT11_16080	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
AOT11_16085	ENOG4105CXT	aspartate transcarbamylase
AOT11_16090	ENOG4105DBV	ornithine carbamoyltransferase
AOT11_16095	ENOG4105CEU	Arginine dihydrolase
AOT11_16110	ENOG4108MJ3	acetyltransferase
AOT11_16120	ENOG4108M3P	Membrane
AOT11_16130	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AOT11_16135	ENOG4105MYG	DNA polymerase iii, chi subunit
AOT11_16140	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AOT11_16145	ENOG4108M8S	permease YjgP YjgQ family protein
AOT11_16150	ENOG4108K5H	permease YjgP YjgQ family protein
AOT11_16170	ENOG4105VZJ	PTS System
AOT11_16180	ENOG4105VCP	PTS System
AOT11_16185	ENOG4105F8D	glycoside hydrolase family 4
AOT11_16195	ENOG4105DDV	Transcriptional regulator (LacI family
AOT11_16290	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_16310	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
AOT11_16315	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
AOT11_16320	ENOG4105CEN	a g-specific adenine glycosylase
AOT11_16325	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AOT11_16330	ENOG4105CSV	Glutaminase
AOT11_16335	ENOG4105CSA	Coproporphyrinogen iii oxidase
AOT11_16340	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AOT11_16350	ENOG4105VZ9	UPF0235 protein
AOT11_16355	ENOG4108VIA	integral membrane protein
AOT11_16360	ENOG4105II7	pyrroline-5-carboxylate reductase
AOT11_16365	ENOG4105DFA	alanine racemase domain protein
AOT11_16370	ENOG4105CZX	twitching motility protein
AOT11_16375	ENOG4105CZX	twitching motility protein
AOT11_16380	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AOT11_16385	ENOG4108UJU	UPF0301 protein
AOT11_16390	ENOG4105D7Z	glutathione synthase
AOT11_16395	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AOT11_16405	ENOG4105RWS	endonuclease I
AOT11_16410	ENOG4105GPY	SprT protein
AOT11_16420	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AOT11_16440	ENOG4105BZA	Phosphoglycerate kinase
AOT11_16445	ENOG4105D2N	Aldolase
AOT11_16450	ENOG4105D64	Mechanosensitive ion channel
AOT11_16455	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
AOT11_16460	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
AOT11_16470	ENOG4108JQ1	Dehydrogenase
AOT11_16475	ENOG4105E66	phosphoriboisomerase A
AOT11_16480	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AOT11_16485	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
AOT11_16495	ENOG4105D0A	hydroxylase
AOT11_16500	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AOT11_16520	ENOG4105Y75	tpr repeat protein
AOT11_16530	ENOG4108IYU	L-aspartate oxidase
AOT11_16535	ENOG4105EMN	RNA polymerase sigma factor
AOT11_16550	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
AOT11_16555	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AOT11_16560	ENOG4105C3F	Signal peptidase i
AOT11_16565	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AOT11_16570	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AOT11_16580	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AOT11_16600	ENOG4105BZU	Histidine kinase
AOT11_16605	ENOG4105BZU	Histidine kinase
AOT11_16615	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AOT11_16620	ENOG4105DXN	mazG family
AOT11_16625	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AOT11_16630	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AOT11_16640	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AOT11_16645	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AOT11_16650	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AOT11_16655	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
AOT11_16670	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AOT11_16675	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AOT11_16680	ENOG4108K5P	(LipO)protein
AOT11_16685	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AOT11_16695	ENOG4107TH8	cina domain protein
AOT11_16700	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AOT11_16705	ENOG4105Y3E	Modulates RecA activity (By similarity)
AOT11_16715	ENOG4105CFH	Aspartokinase
AOT11_16720	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
AOT11_16770	ENOG4107QSA	Oxaloacetate decarboxylase
AOT11_16775	ENOG4105D9Q	decarboxylase (Beta subunit)
AOT11_16785	ENOG4105W39	Membrane
AOT11_16795	ENOG4105D9M	gamma-glutamylcysteine synthetase
AOT11_16805	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
AOT11_16810	ENOG4108JU6	CBS domain protein
AOT11_16815	ENOG4106KVJ	cytochrome C assembly protein
AOT11_16820	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AOT11_16825	ENOG4105K5M	30s ribosomal protein S16
AOT11_16830	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AOT11_16835	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AOT11_16840	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AOT11_16850	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
AOT11_16860	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
AOT11_16865	ENOG4105D7Q	type ii secretion system
AOT11_16870	ENOG4107QHF	type ii secretion system protein e
AOT11_16880	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AOT11_16885	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
AOT11_16890	ENOG41073TP	transcriptional regulator
AOT11_16895	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
AOT11_16900	ENOG4107QSN	dihydrolipoamide acetyltransferase
AOT11_16905	ENOG4107QN2	dihydrolipoyl dehydrogenase
AOT11_16910	ENOG410630P	Transcriptional regulator
AOT11_16915	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AOT11_16920	ENOG41077A9	carbonic anhydrase
AOT11_16925	ENOG4105CHH	sulfate transporter
AOT11_16930	ENOG4105DA5	(ABC) transporter
AOT11_16935	ENOG4105E3A	(ABC) transporter
AOT11_16940	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AOT11_16945	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AOT11_16950	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AOT11_16955	ENOG4105DJ0	Poly(A) Polymerase
AOT11_16960	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
AOT11_16965	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AOT11_16975	ENOG4105CQ7	ATP-dependent helicase
AOT11_16980	ENOG4105BZ4	penicillin-binding protein
AOT11_16985	ENOG4105D78	K07001 NTE family protein
AOT11_16990	ENOG4107QIJ	Aconitate hydratase 2
AOT11_16995	ENOG4105BZW	Glycerate kinase
AOT11_17000	ENOG4105C6Z	Gluconate
AOT11_17005	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
AOT11_17010	ENOG4105XTV	UPF0231 protein
AOT11_17015	ENOG4108YZA	Nitrogen regulatory protein pii
AOT11_17035	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AOT11_17040	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AOT11_17045	ENOG4105E2V	Glycosyltransferase 36
AOT11_17050	ENOG4105E2D	ec 3.2.1.52
AOT11_17055	ENOG4105RD7	BadF BadG BcrA BcrD
AOT11_17065	ENOG4108JQ7	(ABC) transporter
AOT11_17070	ENOG4105C3U	ABC transporter
AOT11_17075	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AOT11_17085	ENOG4107QRA	Extracellular solute-binding protein, family 5
AOT11_17090	ENOG4105BZU	Histidine kinase
AOT11_17095	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AOT11_17100	ENOG4105F4G	Membrane
AOT11_17105	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AOT11_17110	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AOT11_17125	ENOG4105DR5	peptidase
AOT11_17130	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AOT11_17140	ENOG4105WD1	Membrane
AOT11_17145	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
AOT11_17150	ENOG4105FCK	Membrane
AOT11_17155	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AOT11_17160	ENOG4105HBR	Rna-binding protein
AOT11_17165	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AOT11_17170	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AOT11_17175	ENOG4105EEI	dihydropteroate synthase
AOT11_17180	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AOT11_17200	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AOT11_17205	ENOG4105CHV	Transcription elongation factor NusA
AOT11_17210	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AOT11_17215	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AOT11_17220	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AOT11_17225	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AOT11_17245	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AOT11_17250	ENOG4105RT1	May be involved in cell division (By similarity)
AOT11_17260	ENOG4105C3S	Mate efflux family protein
AOT11_17265	ENOG4106RZ4	Peptidase U32
AOT11_17270	ENOG4105CFP	Peptidase U32
AOT11_17275	ENOG4105BZU	Histidine kinase
AOT11_17280	ENOG4105XPQ	lipid carrier protein
AOT11_17285	ENOG4108YYD	acetyltransferase
AOT11_17295	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
AOT11_17300	ENOG4105BZU	Histidine kinase
AOT11_17305	ENOG4105BZU	Histidine kinase
AOT11_17310	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AOT11_17315	ENOG4105EYA	deoxyribonuclease
AOT11_17320	ENOG4105D9N	nucleoside
AOT11_17330	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
AOT11_17335	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
AOT11_17340	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
AOT11_17350	ENOG4105EAC	phosphoserine phosphatase
AOT11_17360	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AOT11_17365	ENOG4105BZU	Histidine kinase
AOT11_17385	ENOG4108IQE	Amp-dependent synthetase and ligase
AOT11_17475	ENOG4105FGV	Chromate
AOT11_17480	ENOG41064T2	transcriptional regulator, lysR family
AOT11_17490	ENOG4107WCA	isomerase
AOT11_17495	ENOG4105E5D	amino acid
AOT11_17500	ENOG4105E5D	amino acid
AOT11_17505	ENOG4105FK9	beta-D-galactosidase beta subunit
AOT11_17510	ENOG4105CNT	hydrolase family 2
AOT11_17520	ENOG4105CQ4	Transcriptional regulator
AOT11_17525	ENOG4105CMR	udp-glucose 4-epimerase
AOT11_17530	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
AOT11_17540	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
AOT11_17545	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_17555	ENOG4108Y51	tRNA-binding protein
AOT11_17570	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AOT11_17585	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AOT11_17590	ENOG4105E98	transcriptional regulator DeoR family
AOT11_17595	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AOT11_17600	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AOT11_17605	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
AOT11_17610	ENOG4105X2V	dna damage-inducible protein
AOT11_17615	ENOG4105EVZ	LysR family transcriptional regulator
AOT11_17625	ENOG4105E68	Sulfatase
AOT11_17630	ENOG4105DSY	exodeoxyribonuclease V, gamma
AOT11_17635	ENOG4107QKA	exodeoxyribonuclease V beta
AOT11_17640	ENOG4107QYX	exodeoxyribonuclease v alpha
AOT11_17650	ENOG4107QZM	n-acetylglutamate synthase
AOT11_17660	ENOG4105CA3	membrane-bound lytic murein transglycosylase
AOT11_17665	ENOG4105CUZ	uba thif-type nad fad binding protein
AOT11_17670	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
AOT11_17675	ENOG4105C9B	Cysteine desulfurase
AOT11_17680	ENOG4107S0N	DJ-1 family
AOT11_17685	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AOT11_17700	ENOG4105K6V	RNA polymerase
AOT11_17710	ENOG4105EYM	Major Facilitator superfamily
AOT11_17715	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AOT11_17725	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AOT11_17730	ENOG4105M85	Bola protein
AOT11_17735	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AOT11_17740	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AOT11_17745	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AOT11_17750	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AOT11_17755	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AOT11_17760	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
AOT11_17765	ENOG4105CJ2	(LipO)protein
AOT11_17775	ENOG4105BZU	Histidine kinase
AOT11_17780	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AOT11_17785	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AOT11_17800	ENOG4105C8J	)-transporter
AOT11_17810	ENOG4105W1I	UPF0253 protein
AOT11_17820	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AOT11_17825	ENOG4108R96	Methyltransferase, YaeB family
AOT11_17840	ENOG4105CFC	Transporter
AOT11_17875	ENOG4105WP7	tRNA pseudouridine synthase C
AOT11_17880	ENOG4105DR9	pseudouridine synthase
AOT11_17885	ENOG4108T8E	UPF0325 protein
AOT11_17900	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AOT11_17905	ENOG4105CE9	30S ribosomal protein S2
AOT11_17910	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AOT11_17915	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AOT11_17925	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AOT11_17930	ENOG4105KNE	Phosphatidate cytidylyltransferase
AOT11_17935	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AOT11_17940	ENOG4105DZP	Membrane-associated zinc metalloprotease
AOT11_17945	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AOT11_17950	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
AOT11_17960	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AOT11_17965	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AOT11_17970	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AOT11_17975	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AOT11_17980	ENOG4105C0B	DNA polymerase III (alpha subunit)
AOT11_17985	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AOT11_17990	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AOT11_17995	ENOG4105N7H	Cytochrome
AOT11_18000	ENOG4108YZA	Nitrogen regulatory protein pii
AOT11_18015	ENOG4105E9H	Lytic Murein transglycosylase
AOT11_18025	ENOG4105D1A	Methyltransferase
AOT11_18030	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AOT11_18035	ENOG4108JDX	DNA polymerase iii, epsilon subunit
AOT11_18045	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
AOT11_18065	ENOG4107QPN	acyl-Coa dehydrogenase
AOT11_18070	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
AOT11_18075	ENOG4105E7A	Glutamine amidotransferase
AOT11_18080	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AOT11_18085	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AOT11_18095	ENOG4105C2W	permease
AOT11_18110	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AOT11_18115	ENOG4105K89	arsenate reductase
AOT11_18120	ENOG4105ERG	peptidase m48, ste24p
AOT11_18135	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AOT11_18140	ENOG4105RH4	Glycine cleavage system transcriptional repressor
AOT11_18150	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AOT11_18165	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AOT11_18170	ENOG4105KUZ	arsenate reductase
AOT11_18195	ENOG4105EZR	dyp-type peroxidase family protein
AOT11_18200	ENOG4105I03	Flagellin
AOT11_18205	ENOG4105I03	Flagellin
AOT11_18210	ENOG4105I03	Flagellin
AOT11_18215	ENOG41063QE	flagellar protein FlaG
AOT11_18220	ENOG4107BRV	flagellar capping protein
AOT11_18230	ENOG4105MQ3	flagellar protein FliS
AOT11_18235	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AOT11_18240	ENOG4105BZU	Histidine kinase
AOT11_18245	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AOT11_18250	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
AOT11_18255	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
AOT11_18260	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AOT11_18270	ENOG4108JIR	Flagellum-specific ATP synthase
AOT11_18290	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AOT11_18295	ENOG4105DD5	Flagellar motor switch protein
AOT11_18300	ENOG4105VTB	flagellar biosynthesis protein fliO
AOT11_18305	ENOG4105CN7	Flagellar biosynthetic protein FliP
AOT11_18310	ENOG4105VS8	Flagellar biosynthetic protein fliq
AOT11_18315	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
AOT11_18320	ENOG4105D00	flagellar biosynthetic protein flhB
AOT11_18325	ENOG4105D7B	Flagellar biosynthesis protein flha
AOT11_18330	ENOG4105FZW	flagellar biosynthesis regulator FlhF
AOT11_18335	ENOG4107R21	site-determining protein
AOT11_18340	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AOT11_18345	ENOG4108VYJ	response regulator receiver protein
AOT11_18350	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
AOT11_18355	ENOG4105CBS	Chea signal transduction histidine kinase
AOT11_18360	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AOT11_18365	ENOG4107QJE	Chromosome Partitioning Protein
AOT11_18375	ENOG4108V3W	Chemotaxis protein, CheW
AOT11_18390	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
AOT11_18395	ENOG41060IM	Heme exporter protein
AOT11_18400	ENOG4105X3C	heme exporter protein
AOT11_18405	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AOT11_18410	ENOG4105DA4	cytochrome c-type biogenesis protein
AOT11_18415	ENOG4107QX9	Thiol disulfide interChange protein
AOT11_18420	ENOG4105KWW	Biogenesis protein
AOT11_18425	ENOG4108M1T	Cytochrome c-type biogenesis protein
AOT11_18430	ENOG410903C	(LipO)protein
AOT11_18435	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
AOT11_18440	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
AOT11_18455	ENOG4105CHU	acetyl-coa acetyltransferase
AOT11_18460	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AOT11_18465	ENOG4108JQM	Insulinase (Peptidase family M16)
AOT11_18470	ENOG4108BY2	phosphohistidine phosphatase
AOT11_18480	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
AOT11_18485	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AOT11_18490	ENOG4105EN6	Membrane
AOT11_18495	ENOG4108BPE	-transporting atpase
AOT11_18500	ENOG4105MH2	YfcL protein
AOT11_18505	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
AOT11_18510	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AOT11_18515	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
AOT11_18520	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AOT11_18530	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AOT11_18535	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AOT11_18540	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AOT11_18545	ENOG4108S3P	Sporulation domain protein
AOT11_18550	ENOG4105E96	Colicin v production protein
AOT11_18555	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AOT11_18560	ENOG4105EJC	lysr family transcriptional regulator
AOT11_18565	ENOG4105I93	response regulator
AOT11_18570	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AOT11_18575	ENOG4107QMP	dna polymerase iii subunits gamma and tau
AOT11_18585	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AOT11_18600	ENOG4105JJR	Histidine kinase
AOT11_18605	ENOG4107EXC	regulatoR
AOT11_18610	ENOG4105C44	Serine transporter
AOT11_18620	ENOG4105CEM	UPF0597 protein
AOT11_18625	ENOG4105WWK	YheO domain protein
AOT11_18630	ENOG4105KRS	Proteinase inhibitor
AOT11_18645	ENOG4108UYE	Lactoylglutathione lyase
AOT11_18655	ENOG4105G6Z	alkaline phosphatase
AOT11_18670	ENOG4105DHI	Methyltransferase
AOT11_18675	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AOT11_18740	ENOG41061P8	Persistence to inhibition of murein or DNA biosynthesis regulatory protein
AOT11_18745	ENOG4105CAF	HipA N-terminal domain protein
AOT11_18750	ENOG4105DFP	Integrase
AOT11_18760	ENOG4105BZU	Histidine kinase
AOT11_18770	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_18780	ENOG4108M3R	transcriptional activator CadC
AOT11_18785	ENOG4105D5Q	Arginine ornithine antiporter
AOT11_18790	ENOG4105CXN	decarboxylase
AOT11_18795	ENOG4105BZU	Histidine kinase
AOT11_18810	ENOG4107SXA	Phosphorylase
AOT11_18820	ENOG4108NVR	Methyl-accepting chemotaxis
AOT11_18825	ENOG4105K59	histidine triad (HIT) protein
AOT11_18850	ENOG4105D0Y	UPF0227 protein
AOT11_18855	ENOG4105CEP	NADH dehydrogenase
AOT11_18870	ENOG4108JA2	transcriptioN-repair coupling factor
AOT11_18880	ENOG4105D60	lipoprotein releasing system transmembrane protein
AOT11_18885	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AOT11_18890	ENOG4105D60	lipoprotein releasing system transmembrane protein
AOT11_18900	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
AOT11_18905	ENOG4105BZ1	(ABC) transporter
AOT11_18915	ENOG4105W49	UPF0434 protein
AOT11_18925	ENOG4108KHP	Diguanylate cyclase
AOT11_18930	ENOG4105ED1	spovr family
AOT11_18940	ENOG4105CYN	Serine protein kinase
AOT11_18945	ENOG4105XWI	UPF0304 protein
AOT11_18955	ENOG4105F1A	Pyruvate formate-lyase
AOT11_18960	ENOG4108NVR	Methyl-accepting chemotaxis
AOT11_18970	ENOG4105C6N	Formate acetyltransferase
AOT11_18985	ENOG4108JEH	abc transporter atp-binding protein
AOT11_18990	ENOG4105E89	ABC transporter
AOT11_18995	ENOG4105DSP	amino acid AbC transporter
AOT11_19010	ENOG4105CGK	Exodeoxyribonuclease III
AOT11_19015	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_19020	ENOG4106428	Protein of unknown function (DUF2496)
AOT11_19025	ENOG4108URS	primosomal replication protein n''
AOT11_19035	ENOG4105DVT	helicase
AOT11_19040	ENOG4105ZU8	porin-like protein H
AOT11_19050	ENOG4108R99	pseudouridine synthase
AOT11_19060	ENOG4105VEQ	Cold shock protein
AOT11_19065	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AOT11_19070	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AOT11_19075	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AOT11_19085	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AOT11_19100	ENOG4105RKX	Protein of unknown function (DUF2498)
AOT11_19105	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AOT11_19120	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AOT11_19140	ENOG4105HP8	regulator of competence-specific genes
AOT11_19145	ENOG4105ETE	Transcriptional regulator (LacI family
AOT11_19150	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
AOT11_19155	ENOG4106WF9	DNA-binding transcriptional regulator TorR
AOT11_19160	ENOG4107S90	membrAne
AOT11_19165	ENOG4106371	Methyltransferase
AOT11_19175	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
AOT11_19195	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AOT11_19200	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
AOT11_19215	ENOG4105C9M	aspartyl-trna synthetase
AOT11_19220	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AOT11_19225	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AOT11_19235	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AOT11_19240	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AOT11_19250	ENOG4107YD3	Thioesterase
AOT11_19255	ENOG4105E02	MotA TolQ exbB proton channel
AOT11_19260	ENOG4105M8F	Biopolymer transport protein exbD tolR
AOT11_19275	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AOT11_19280	ENOG4105UFD	tol-pal system protein YbgF
AOT11_19295	ENOG4105Z6B	inner membrane protein yjfl
AOT11_19305	ENOG4106032	Glutathionylspermidine synthase
AOT11_19320	ENOG4108RNS	Exports L-alanine (By similarity)
AOT11_19420	ENOG4105YGK	Pfam:UPF0157
AOT11_19435	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
AOT11_19440	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_19445	ENOG4105C5I	Dehydrogenase
AOT11_19450	ENOG4105EE5	Membrane protein terC
AOT11_19470	ENOG4108R6W	Transcriptional regulator, ARAC family
AOT11_19485	ENOG4105BZU	Histidine kinase
AOT11_19495	ENOG4105BZU	Histidine kinase
AOT11_19500	ENOG4105BZU	Histidine kinase
AOT11_19515	ENOG4105DZ2	Transcriptional regulator
AOT11_19520	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
AOT11_19525	ENOG4108DNC	Involved in acetate metabolism (By similarity)
AOT11_19530	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AOT11_19545	ENOG4105C7J	ABC transporter, permease
AOT11_19550	ENOG4108JJB	ABC transporter
AOT11_19555	ENOG4107R28	alpha amylase, catalytic region
AOT11_19560	ENOG4105BZU	Histidine kinase
AOT11_19565	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
AOT11_19570	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AOT11_19575	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
AOT11_19585	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
AOT11_19590	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
AOT11_19615	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
AOT11_19620	ENOG4105EAQ	(twin-arginine translocation) pathway signal
AOT11_19625	ENOG4105C5X	domain protein
AOT11_19640	ENOG4105CH5	extracellular solute-binding protein, family 7
AOT11_19650	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AOT11_19665	ENOG41067TZ	transcriptional regulator, MarR family
AOT11_19670	ENOG4105C94	Transporter
AOT11_19675	ENOG4105C8Q	Methyl-accepting chemotaxis
AOT11_19695	ENOG4105CGF	Aromatic amino acid aminotransferase
AOT11_19700	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AOT11_19715	ENOG4105C5S	asparaginyl-tRNA synthetase
AOT11_19720	ENOG4108N3W	hemolysin secretion protein
AOT11_19725	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
AOT11_19740	ENOG4105BZU	Histidine kinase
AOT11_19745	ENOG4105EJQ	L-serine dehydratase
AOT11_19750	ENOG4105C44	Serine transporter
AOT11_19755	ENOG4105P8F	nudix hydrolase
AOT11_19765	ENOG4105BZU	Histidine kinase
AOT11_19770	ENOG4105CRQ	synthase (Component I)
AOT11_19785	ENOG4105CM6	amino acid regulated cytosolic protein
AOT11_19795	ENOG4108JU8	Transcriptional regulator
AOT11_19800	ENOG4105D9U	N-acetyltransferase
AOT11_19815	ENOG4105C8P	)-transporter
AOT11_19820	ENOG4105BZU	Histidine kinase
AOT11_19830	ENOG4105BZU	Histidine kinase
AOT11_19835	ENOG4108KMM	Diguanylate cyclase
AOT11_19845	ENOG4105CPI	Metal Dependent Phosphohydrolase
AOT11_19850	ENOG4105BZU	Histidine kinase
AOT11_19855	ENOG4105G0K	glycine radical enzyme YjjI family
AOT11_19860	ENOG41076CZ	activating enzyme
AOT11_19880	ENOG4105DHT	Metal Dependent Phosphohydrolase
AOT11_19885	ENOG4108NRW	Phospholipase, patatin family
AOT11_19895	ENOG4105CBD	Diacylglycerol kinase
AOT11_19900	ENOG4105E0U	tyrosine-specific transport protein
AOT11_19905	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
AOT11_19910	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AOT11_19915	ENOG4108RMU	ferritin dps family protein
AOT11_19930	ENOG4105BZ1	(ABC) transporter
AOT11_19935	ENOG4105BZ1	(ABC) transporter
AOT11_19940	ENOG4105BZG	amino acid carrier protein
AOT11_19955	ENOG4105DAY	polysaccharide export protein
AOT11_19985	ENOG4107RA4	Glycosyl transferase (Group 1
AOT11_20010	ENOG4105BZU	Histidine kinase
AOT11_20040	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
AOT11_20045	ENOG4105CFG	Acts as a chaperone (By similarity)
AOT11_20055	ENOG4106TD9	Diguanylate cyclase
AOT11_20075	ENOG4105GNX	MltA-interacting MipA family protein
AOT11_20115	ENOG4107QMS	site-determining protein
AOT11_20165	ENOG4105CQ7	ATP-dependent helicase
AOT11_20190	ENOG4107IFA	Lipase (EC 3.1.1.3)
AOT11_20200	ENOG4105E5M	Multidrug resistance protein D
AOT11_20205	ENOG4105CYW	agmatinase
AOT11_20210	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
AOT11_20270	ENOG4105BZU	Histidine kinase
AOT11_20275	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AOT11_20280	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AOT11_20285	ENOG4107RH7	Nicotinate phosphoribosyltransferase
AOT11_20300	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AOT11_20310	ENOG4105FQ6	thiopurine methyltransferase
AOT11_20315	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
AOT11_20335	ENOG4108ZG0	Ompa motb domain protein
AOT11_20350	ENOG4105CQB	FAD linked oxidase domain protein
AOT11_20370	ENOG4105C84	Histidine ammonia-lyase
AOT11_20380	ENOG41088SP	formiminoglutamate hydrolase
AOT11_20395	ENOG4108N23	SpoOM-related protein
AOT11_20405	ENOG4105C22	threonyL-tRNA synthetase
AOT11_20410	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AOT11_20415	ENOG41082NX	50s ribosomal protein l35
AOT11_20420	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AOT11_20470	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AOT11_20480	ENOG4105EKQ	RNA-directed DNA polymerase
AOT11_20485	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
AOT11_20640	ENOG4108V5Q	transglutaminase-like protein
AOT11_20650	ENOG4108S58	Phenazine biosynthesis protein PhzF
AOT11_20755	ENOG4105KNA	-acetyltransferase
AOT11_20785	ENOG4105EKQ	RNA-directed DNA polymerase
AOT11_20820	ENOG4105EKQ	RNA-directed DNA polymerase
AOT11_20855	ENOG4105RHY	Pfam:UPF0157
AOT11_20940	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
AOT11_20990	ENOG4108V5Q	transglutaminase-like protein
AOT11_21015	ENOG4105EKQ	RNA-directed DNA polymerase
AOT11_21065	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
AOT11_21115	ENOG4105KNA	-acetyltransferase
AOT11_21185	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AOT11_21295	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
AOT11_21300	ENOG4105K4U	addiction module toxin, RelE StbE family
AOT11_21355	ENOG4108R6K	riboflavin synthase, subunit alpha
AOT11_21365	ENOG4105FGM	Fructosamine kinase
AOT11_21375	ENOG4105BZU	Histidine kinase
AOT11_21385	ENOG4107TT5	NLP P60 protein
AOT11_21390	ENOG4108N3W	hemolysin secretion protein
AOT11_21400	ENOG4106IUH	DTW domain containing protein
AOT11_21405	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
AOT11_21415	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AOT11_21425	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AOT11_21430	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
AOT11_21440	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AOT11_21445	ENOG4105BZU	Histidine kinase
AOT11_21460	ENOG4105C5H	ABC transporter
AOT11_21470	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AOT11_21500	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AOT11_21505	ENOG4105QAX	Iron-sulfur
AOT11_21545	ENOG4107RUE	extracellular solute-binding protein family 1
AOT11_21550	ENOG4107RUE	extracellular solute-binding protein family 1
AOT11_21555	ENOG4105D38	putrescine abc transporter
AOT11_21560	ENOG4105F38	ABC transporter, permease
AOT11_21570	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
AOT11_21585	ENOG4105C59	p-type ATPase
AOT11_21595	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
AOT11_21610	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
AOT11_21625	ENOG4105BZU	Histidine kinase
AOT11_21650	ENOG4105DAN	ATP-dependent protease
AOT11_21655	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
AOT11_21670	ENOG4105C5H	ABC transporter
AOT11_21685	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
AOT11_21690	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AOT11_21695	ENOG4105C7I	Dehydrogenase
AOT11_21700	ENOG4105CD8	aminopeptidase N
AOT11_21710	ENOG4105CN1	protease
AOT11_21715	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
AOT11_21720	ENOG4108ZGC	gaf domain protein
AOT11_21725	ENOG4105BZ1	(ABC) transporter
AOT11_21730	ENOG4105H2K	paraquat-inducible protein a
AOT11_21735	ENOG4105DY2	Paraquat-inducible protein b
AOT11_21740	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AOT11_21745	ENOG4105QNR	S1 RNA binding domain protein
AOT11_21760	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AOT11_21765	ENOG4108VPT	UPF0234 protein
AOT11_21770	ENOG4105BZU	Histidine kinase
AOT11_21780	ENOG4105WN5	stage II sporulation protein
AOT11_21790	ENOG4107V1M	polysaccharide export protein
AOT11_21805	ENOG4105BZU	Histidine kinase
AOT11_21810	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AOT11_21855	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AOT11_21895	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
AOT11_21900	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
AOT11_21905	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
AOT11_21910	ENOG4106YYS	transcriptional regulatory protein
AOT11_21915	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AOT11_21930	ENOG4107V40	secretion protein, HlyD family
AOT11_21955	ENOG4105BZG	amino acid carrier protein
AOT11_21965	ENOG4108NIW	Leucine export protein LeuE
AOT11_21970	ENOG4105CTD	carboxy-peptidase
AOT11_21975	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
AOT11_21980	ENOG4105GXZ	Ferredoxin-type protein NapH
AOT11_21985	ENOG4108BGM	Quinol dehydrogenase periplasmic component
AOT11_21995	ENOG4107QXX	ABC transporter
AOT11_22000	ENOG4105EZ7	amino acid ABC transporter
AOT11_22005	ENOG4105DRP	amino acid AbC transporter
AOT11_22010	ENOG4105CDA	abc transporter atp-binding protein
AOT11_22015	ENOG4108MN8	Membrane
AOT11_22020	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
AOT11_22025	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
AOT11_22030	ENOG4105C8Q	Methyl-accepting chemotaxis