locus-tag	class	description
AOT11_00025	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AOT11_00035	COG1596	polysaccharide export
AOT11_00105	COG0714	Associated with various cellular activities
AOT11_00125	COG2304	oxidoreductase activity
AOT11_00135	COG5001	Diguanylate cyclase
AOT11_00135	COG4251	negative regulation of phosphorylation
AOT11_00135	COG2203	Gaf domain
AOT11_00135	COG3706	GGDEF domain
AOT11_00145	COG0581	inorganic phosphate transmembrane transporter activity
AOT11_00150	COG0573	inorganic phosphate transmembrane transporter activity
AOT11_00155	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AOT11_00190	COG0513	Belongs to the DEAD box helicase family
AOT11_00200	COG1376	ErfK ybiS ycfS ynhG family protein
AOT11_00200	COG1388	LysM domain
AOT11_00205	COG0415	Belongs to the DNA photolyase family
AOT11_00210	COG0789	Transcriptional regulator
AOT11_00215	COG3272	Protein of unknown function (DUF1722)
AOT11_00235	COG3706	GGDEF domain
AOT11_00245	COG1566	PFAM secretion protein HlyD family protein
AOT11_00250	COG4720	Psort location CytoplasmicMembrane, score
AOT11_00255	COG1122	ATPase activity
AOT11_00270	COG0793	Belongs to the peptidase S41A family
AOT11_00270	COG4946	Tricorn protease homolog
AOT11_00275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOT11_00300	COG0668	transmembrane transport
AOT11_00320	COG1538	Outer membrane efflux protein
AOT11_00330	COG2274	protein secretion by the type I secretion system
AOT11_00340	COG3111	PFAM Bacterial OB fold (BOF) protein
AOT11_00390	COG3040	lipid binding
AOT11_00440	COG3240	lipase activity
AOT11_00455	COG2211	Major facilitator Superfamily
AOT11_00465	COG0346	lactoylglutathione lyase activity
AOT11_00485	COG0753	catalase activity
AOT11_00505	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AOT11_00515	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AOT11_00530	COG0393	Putative heavy-metal-binding
AOT11_00550	COG4771	TonB-dependent receptor
AOT11_00555	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AOT11_00575	COG2814	Major facilitator Superfamily
AOT11_00640	COG0351	phosphomethylpyrimidine kinase
AOT11_00645	COG0671	phosphoesterase, PA-phosphatase related
AOT11_00660	COG0561	phosphatase activity
AOT11_00675	COG0076	glutamate decarboxylase activity
AOT11_00680	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOT11_00705	COG4221	oxidoreductase activity
AOT11_00720	COG0745	RESPONSE REGULATOR receiver
AOT11_00725	COG2205	protein histidine kinase activity
AOT11_00730	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AOT11_00735	COG2194	sulfuric ester hydrolase activity
AOT11_00740	COG1368	sulfuric ester hydrolase activity
AOT11_00755	COG2356	endonuclease I
AOT11_00770	COG3706	GGDEF domain
AOT11_00780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOT11_00815	COG2175	clavaminate synthase activity
AOT11_00820	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AOT11_00865	COG1301	dicarboxylic acid transport
AOT11_00875	COG0137	argininosuccinate synthase activity
AOT11_00890	COG0583	DNA-binding transcription factor activity
AOT11_00910	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AOT11_00935	COG4934	collagen metabolic process
AOT11_00945	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AOT11_00950	COG1482	cell wall glycoprotein biosynthetic process
AOT11_00955	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AOT11_00960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AOT11_00960	COG1263	PTS System
AOT11_00965	COG1609	Transcriptional regulator
AOT11_00975	COG3383	formate dehydrogenase (NAD+) activity
AOT11_00990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOT11_00990	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AOT11_00990	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AOT11_00995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AOT11_01005	COG3537	Alpha-1,2-mannosidase
AOT11_01015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AOT11_01020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AOT11_01030	COG2207	Transcriptional regulator
AOT11_01035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AOT11_01035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOT11_01035	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AOT11_01040	COG1482	cell wall glycoprotein biosynthetic process
AOT11_01090	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AOT11_01095	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AOT11_01100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOT11_01105	COG2211	Major facilitator Superfamily
AOT11_01130	COG1129	ABC transporter
AOT11_01140	COG1609	Transcriptional regulator
AOT11_01165	COG0564	pseudouridine synthase activity
AOT11_01190	COG1566	PFAM secretion protein HlyD family protein
AOT11_01200	COG0534	Mate efflux family protein
AOT11_01205	COG1472	Belongs to the glycosyl hydrolase 3 family
AOT11_01215	COG4580	involved in the transport of maltose and maltodextrins
AOT11_01230	COG1609	Transcriptional regulator
AOT11_01240	COG4608	Belongs to the ABC transporter superfamily
AOT11_01245	COG0444	Belongs to the ABC transporter superfamily
AOT11_01250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOT11_01260	COG0747	negative chemotaxis
AOT11_01270	COG1609	Transcriptional regulator
AOT11_01280	COG2723	6-phospho-beta-galactosidase activity
AOT11_01285	COG0395	ABC-type sugar transport system, permease component
AOT11_01300	COG1609	Transcriptional regulator
AOT11_01320	COG2199	diguanylate cyclase activity
AOT11_01325	COG0745	RESPONSE REGULATOR receiver
AOT11_01330	COG0642	Histidine kinase
AOT11_01340	COG0583	DNA-binding transcription factor activity
AOT11_01350	COG0612	Peptidase, M16
AOT11_01355	COG1283	sodium-dependent phosphate transmembrane transporter activity
AOT11_01360	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AOT11_01365	COG0625	glutathione transferase activity
AOT11_01370	COG1012	belongs to the aldehyde dehydrogenase family
AOT11_01385	COG0560	Phosphoserine phosphatase
AOT11_01420	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AOT11_01425	COG0840	transmembrane signaling receptor activity
AOT11_01435	COG1640	4-alpha-glucanotransferase
AOT11_01440	COG0058	SHG alpha-glucan phosphorylase activity
AOT11_01470	COG3842	ATPase activity
AOT11_01480	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOT11_01490	COG2182	Extracellular solute-binding protein
AOT11_01495	COG1175	transmembrane transport
AOT11_01500	COG3833	ABC-type maltose transport systems, permease component
AOT11_01535	COG1999	signal sequence binding
AOT11_01540	COG2847	Copper chaperone PCu(A)C
AOT11_01545	COG1162	GTPase activity
AOT11_01550	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AOT11_01560	COG0531	amino acid
AOT11_01565	COG1982	Orn Lys Arg decarboxylase major
AOT11_01620	COG3706	GGDEF domain
AOT11_01625	COG5001	Diguanylate cyclase
AOT11_01630	COG1741	Belongs to the pirin family
AOT11_01660	COG1309	transcriptional regulator
AOT11_01680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AOT11_01685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AOT11_01690	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AOT11_01725	COG0786	glutamate:sodium symporter activity
AOT11_01730	COG0786	glutamate:sodium symporter activity
AOT11_01750	COG3275	phosphorelay sensor kinase activity
AOT11_01765	COG4591	ABC-type transport system involved in lipoprotein release permease component
AOT11_01770	COG1136	(ABC) transporter
AOT11_01780	COG0217	transcriptional regulatory protein
AOT11_01800	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
AOT11_01800	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AOT11_01810	COG0444	Belongs to the ABC transporter superfamily
AOT11_01815	COG4608	Belongs to the ABC transporter superfamily
AOT11_01840	COG1444	tRNA N-acetyltransferase activity
AOT11_01850	COG0745	RESPONSE REGULATOR receiver
AOT11_01865	COG0835	chemotaxis
AOT11_01870	COG0840	transmembrane signaling receptor activity
AOT11_01875	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AOT11_01880	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AOT11_01885	COG2201	protein-glutamate methylesterase activity
AOT11_01890	COG0840	transmembrane signaling receptor activity
AOT11_01900	COG3706	GGDEF domain
AOT11_01900	COG0745	RESPONSE REGULATOR receiver
AOT11_01920	COG2963	transposase activity
AOT11_01940	COG0406	alpha-ribazole phosphatase activity
AOT11_01965	COG1737	Transcriptional regulator
AOT11_01970	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AOT11_01970	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AOT11_02005	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AOT11_02010	COG3069	C4-dicarboxylate transmembrane transporter activity
AOT11_02040	COG2204	response regulator
AOT11_02090	COG1132	(ABC) transporter
AOT11_02105	COG3623	hexulose-6-phosphate isomerase
AOT11_02110	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AOT11_02115	COG0561	phosphatase activity
AOT11_02145	COG1902	pentaerythritol trinitrate reductase activity
AOT11_02155	COG2814	Major facilitator Superfamily
AOT11_02160	COG1028	Short-chain dehydrogenase reductase Sdr
AOT11_02175	COG0800	Aldolase
AOT11_02180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOT11_02185	COG1904	glucuronate isomerase
AOT11_02190	COG0246	Mannitol dehydrogenase
AOT11_02200	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AOT11_02210	COG2186	Transcriptional regulator
AOT11_02220	COG0513	Belongs to the DEAD box helicase family
AOT11_02250	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AOT11_02255	COG0732	type I restriction modification DNA specificity domain
AOT11_02260	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AOT11_02270	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AOT11_02275	COG2258	MOSC domain
AOT11_02305	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AOT11_02320	COG0840	transmembrane signaling receptor activity
AOT11_02340	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOT11_02345	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOT11_02395	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AOT11_02410	COG1349	DNA-binding transcription factor activity
AOT11_02420	COG1349	DNA-binding transcription factor activity
AOT11_02430	COG2222	sugar isomerase
AOT11_02435	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AOT11_02445	COG3716	PTS system mannose fructose sorbose family IID component
AOT11_02450	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOT11_02480	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AOT11_02485	COG1120	ATPase activity
AOT11_02515	COG0577	efflux transmembrane transporter activity
AOT11_02515	COG1136	(ABC) transporter
AOT11_02520	COG1136	(ABC) transporter
AOT11_02520	COG0577	efflux transmembrane transporter activity
AOT11_02525	COG2176	DNA-directed DNA polymerase activity
AOT11_02550	COG3706	GGDEF domain
AOT11_02560	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AOT11_02580	COG2205	protein histidine kinase activity
AOT11_02595	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AOT11_02630	COG0579	oxidoreductase
AOT11_02640	COG3437	response regulator, receiver
AOT11_02660	COG1357	PFAM Pentapeptide repeats (8 copies)
AOT11_02670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOT11_02705	COG0513	Belongs to the DEAD box helicase family
AOT11_02725	COG0583	DNA-binding transcription factor activity
AOT11_02735	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOT11_02765	COG2814	Major facilitator Superfamily
AOT11_02770	COG2207	Transcriptional regulator
AOT11_02785	COG1858	cytochrome C peroxidase
AOT11_02810	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AOT11_02815	COG0454	-acetyltransferase
AOT11_02830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AOT11_02830	COG1263	PTS System
AOT11_02845	COG3046	protein related to deoxyribodipyrimidine photolyase
AOT11_02850	COG2207	Transcriptional regulator
AOT11_02855	COG1881	PFAM PEBP family protein
AOT11_02860	COG0494	nUDIX hydrolase
AOT11_02895	COG0668	transmembrane transport
AOT11_02935	COG1028	Short-chain dehydrogenase reductase Sdr
AOT11_02940	COG1917	Cupin 2, conserved barrel domain protein
AOT11_02955	COG0729	surface antigen
AOT11_02960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOT11_02965	COG2272	Belongs to the type-B carboxylesterase lipase family
AOT11_02990	COG2985	domain, Protein
AOT11_03000	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AOT11_03015	COG0583	DNA-binding transcription factor activity
AOT11_03025	COG0697	spore germination
AOT11_03030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOT11_03035	COG0800	Aldolase
AOT11_03040	COG0366	Alpha amylase catalytic
AOT11_03050	COG3366	ferrous iron transmembrane transporter activity
AOT11_03055	COG0700	Nucleoside recognition
AOT11_03060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOT11_03085	COG2194	sulfuric ester hydrolase activity
AOT11_03090	COG0583	DNA-binding transcription factor activity
AOT11_03100	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AOT11_03125	COG0673	inositol 2-dehydrogenase activity
AOT11_03130	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AOT11_03135	COG2197	response regulator
AOT11_03140	COG0384	phenazine biosynthesis protein PhzF
AOT11_03150	COG0625	glutathione transferase activity
AOT11_03155	COG1879	ABC-type sugar transport system periplasmic component
AOT11_03165	COG3284	Transcriptional regulator
AOT11_03170	COG1012	belongs to the aldehyde dehydrogenase family
AOT11_03175	COG1253	flavin adenine dinucleotide binding
AOT11_03185	COG0242	peptide deformylase activity
AOT11_03200	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOT11_03205	COG1609	Transcriptional regulator
AOT11_03220	COG0488	(ABC) transporter
AOT11_03225	COG0814	amino acid
AOT11_03240	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOT11_03260	COG0189	ligase activity
AOT11_03260	COG4067	protein conserved in archaea
AOT11_03275	COG1629	transport
AOT11_03275	COG4774	siderophore transport
AOT11_03280	COG4607	ABC-type enterochelin transport system periplasmic component
AOT11_03290	COG1021	2,3-dihydroxybenzoate-AMP ligase
AOT11_03310	COG1021	2,3-dihydroxybenzoate-AMP ligase
AOT11_03315	COG1169	isochorismate synthase
AOT11_03320	COG1028	Short-chain dehydrogenase reductase Sdr
AOT11_03325	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AOT11_03355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOT11_03360	COG0840	transmembrane signaling receptor activity
AOT11_03370	COG2755	lipolytic protein G-D-S-L family
AOT11_03375	COG5001	Diguanylate cyclase
AOT11_03375	COG5002	protein histidine kinase activity
AOT11_03390	COG4160	amino acid transport
AOT11_03395	COG4215	(ABC) transporter
AOT11_03400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOT11_03405	COG1126	abc transporter atp-binding protein
AOT11_03410	COG3015	lipoprotein NlpE involved in copper resistance
AOT11_03425	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AOT11_03465	COG2814	Major facilitator Superfamily
AOT11_03490	COG1139	Iron-sulfur cluster binding protein
AOT11_03500	COG1620	l-lactate permease
AOT11_03505	COG0583	DNA-binding transcription factor activity
AOT11_03510	COG1505	serine-type exopeptidase activity
AOT11_03515	COG4172	Belongs to the ABC transporter superfamily
AOT11_03525	COG1067	ATP-dependent peptidase activity
AOT11_03530	COG0402	S-adenosylhomocysteine deaminase activity
AOT11_03535	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AOT11_03545	COG2239	Acts as a magnesium transporter
AOT11_03575	COG0121	glutamine amidotransferase
AOT11_03585	COG1522	sequence-specific DNA binding
AOT11_03610	COG0583	DNA-binding transcription factor activity
AOT11_03635	COG0784	Response regulator, receiver
AOT11_03635	COG5002	protein histidine kinase activity
AOT11_03635	COG2205	protein histidine kinase activity
AOT11_03650	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AOT11_03685	COG0383	alpha-mannosidase activity
AOT11_03705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOT11_03720	COG1482	cell wall glycoprotein biosynthetic process
AOT11_03740	COG3132	Protein of unknown function, DUF480
AOT11_03745	COG2827	Endonuclease containing a URI domain
AOT11_03800	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOT11_03805	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOT11_03815	COG0183	Belongs to the thiolase family
AOT11_03835	COG3005	denitrification pathway
AOT11_03845	COG0243	molybdopterin cofactor binding
AOT11_03855	COG3850	Histidine kinase
AOT11_03860	COG2197	response regulator
AOT11_03880	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AOT11_03880	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AOT11_03905	COG1538	Outer membrane efflux protein
AOT11_03910	COG1566	PFAM secretion protein HlyD family protein
AOT11_03920	COG1473	amidohydrolase
AOT11_03955	COG0183	Belongs to the thiolase family
AOT11_03965	COG0427	acetyl-CoA hydrolase
AOT11_04000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AOT11_04015	COG3568	Endonuclease Exonuclease Phosphatase
AOT11_04040	COG0513	Belongs to the DEAD box helicase family
AOT11_04055	COG1846	Transcriptional regulator
AOT11_04090	COG0842	Transport permease protein
AOT11_04095	COG1131	(ABC) transporter
AOT11_04105	COG1737	Transcriptional regulator
AOT11_04105	COG0837	glucose binding
AOT11_04115	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AOT11_04140	COG0251	oxidation-reduction process
AOT11_04145	COG3706	GGDEF domain
AOT11_04145	COG5001	Diguanylate cyclase
AOT11_04145	COG4251	negative regulation of phosphorylation
AOT11_04145	COG2203	Gaf domain
AOT11_04150	COG0583	DNA-binding transcription factor activity
AOT11_04155	COG2814	Major facilitator Superfamily
AOT11_04170	COG0697	spore germination
AOT11_04185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOT11_04195	COG1764	response to oxidative stress
AOT11_04200	COG1846	Transcriptional regulator
AOT11_04225	COG1280	lysine exporter protein (LysE YggA)
AOT11_04235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOT11_04240	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AOT11_04245	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AOT11_04250	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AOT11_04275	COG1612	heme a metabolic process
AOT11_04280	COG0109	protoheme IX farnesyltransferase activity
AOT11_04290	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AOT11_04295	COG0840	transmembrane signaling receptor activity
AOT11_04310	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AOT11_04315	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AOT11_04335	COG2897	thiosulfate sulfurtransferase activity
AOT11_04340	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AOT11_04345	COG0303	'Molybdopterin
AOT11_04375	COG4989	oxidoreductase activity
AOT11_04385	COG2195	Cleaves the N-terminal amino acid of tripeptides
AOT11_04405	COG0840	transmembrane signaling receptor activity
AOT11_04410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOT11_04415	COG0545	Peptidyl-prolyl cis-trans isomerase
AOT11_04445	COG1278	Cold shock
AOT11_04450	COG3036	rescue of stalled ribosome
AOT11_04460	COG2203	Gaf domain
AOT11_04460	COG2199	diguanylate cyclase activity
AOT11_04470	COG1482	cell wall glycoprotein biosynthetic process
AOT11_04475	COG2271	Major facilitator Superfamily
AOT11_04480	COG3851	Histidine kinase
AOT11_04485	COG2197	response regulator
AOT11_04505	COG2130	NADP-dependent
AOT11_04510	COG1309	transcriptional regulator
AOT11_04525	COG1278	Cold shock
AOT11_04535	COG0450	alkyl hydroperoxide reductase
AOT11_04545	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AOT11_04550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOT11_04555	COG1960	acyl-CoA dehydrogenase activity
AOT11_04565	COG0183	Belongs to the thiolase family
AOT11_04580	COG1024	Enoyl-CoA hydratase
AOT11_04585	COG1024	Enoyl-CoA hydratase
AOT11_04595	COG1028	Short-chain dehydrogenase reductase Sdr
AOT11_04605	COG5642	Protein of unknown function (DUF2384)
AOT11_04640	COG2994	toxin metabolic process
AOT11_04645	COG1073	alpha beta
AOT11_04645	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AOT11_04645	COG3064	Membrane
AOT11_04700	COG3437	response regulator, receiver
AOT11_04700	COG0784	Response regulator, receiver
AOT11_04705	COG4191	Histidine kinase
AOT11_04705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOT11_04715	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AOT11_04740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOT11_04745	COG3186	Phenylalanine-4-hydroxylase
AOT11_04770	COG3530	Putative quorum-sensing-regulated virulence factor
AOT11_04790	COG0515	serine threonine protein kinase
AOT11_04790	COG2815	serine threonine protein kinase
AOT11_04825	COG0631	protein serine/threonine phosphatase activity
AOT11_04880	COG3501	Rhs element vgr protein
AOT11_04895	COG3209	COG3209 Rhs family protein
AOT11_04905	COG3209	COG3209 Rhs family protein
AOT11_04910	COG5444	nuclease activity
AOT11_04930	COG0501	Belongs to the peptidase M48B family
AOT11_04935	COG1704	LemA family
AOT11_04940	COG3069	C4-dicarboxylate transmembrane transporter activity
AOT11_04950	COG0312	modulator of DNA gyrase
AOT11_04955	COG0312	modulator of DNA gyrase
AOT11_04960	COG0584	glycerophosphoryl diester phosphodiesterase
AOT11_04965	COG2271	Major facilitator Superfamily
AOT11_04990	COG0366	Alpha amylase catalytic
AOT11_05000	COG0243	molybdopterin cofactor binding
AOT11_05005	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AOT11_05005	COG1648	precorrin-2 dehydrogenase activity
AOT11_05020	COG3707	response regulator
AOT11_05025	COG1116	anion transmembrane transporter activity
AOT11_05025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOT11_05030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOT11_05035	COG1116	anion transmembrane transporter activity
AOT11_05040	COG2146	nitrite reductase [NAD(P)H] activity
AOT11_05040	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOT11_05055	COG2199	diguanylate cyclase activity
AOT11_05055	COG2203	Gaf domain
AOT11_05065	COG0523	cobalamin synthesis protein
AOT11_05075	COG0513	Belongs to the DEAD box helicase family
AOT11_05080	COG0010	Belongs to the arginase family
AOT11_05090	COG5001	Diguanylate cyclase
AOT11_05090	COG4251	negative regulation of phosphorylation
AOT11_05090	COG2203	Gaf domain
AOT11_05090	COG3706	GGDEF domain
AOT11_05100	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AOT11_05130	COG0840	transmembrane signaling receptor activity
AOT11_05135	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOT11_05140	COG2146	nitrite reductase [NAD(P)H] activity
AOT11_05170	COG0811	peptide transport
AOT11_05175	COG0811	peptide transport
AOT11_05180	COG0848	biopolymer transport protein
AOT11_05195	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AOT11_05200	COG0840	transmembrane signaling receptor activity
AOT11_05215	COG0534	Mate efflux family protein
AOT11_05230	COG3118	belongs to the thioredoxin family
AOT11_05235	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOT11_05290	COG1328	CTP reductase activity
AOT11_05295	COG0602	queuosine metabolic process
AOT11_05305	COG0189	ligase activity
AOT11_05305	COG4067	protein conserved in archaea
AOT11_05325	COG0725	ABC transporter, periplasmic molybdate-binding protein
AOT11_05330	COG4149	molybdate abc transporter
AOT11_05340	COG0697	spore germination
AOT11_05345	COG1846	Transcriptional regulator
AOT11_05355	COG0745	RESPONSE REGULATOR receiver
AOT11_05365	COG3706	GGDEF domain
AOT11_05385	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AOT11_05395	COG0745	RESPONSE REGULATOR receiver
AOT11_05410	COG0023	Translation Initiation Factor
AOT11_05420	COG1181	Belongs to the D-alanine--D-alanine ligase family
AOT11_05430	COG0045	succinate-CoA ligase (ADP-forming) activity
AOT11_05430	COG1042	CoA-binding domain protein
AOT11_05430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOT11_05435	COG0583	DNA-binding transcription factor activity
AOT11_05445	COG5001	Diguanylate cyclase
AOT11_05445	COG5002	protein histidine kinase activity
AOT11_05445	COG3447	MASE1 domain protein
AOT11_05455	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AOT11_05460	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AOT11_05465	COG1984	allophanate hydrolase subunit 2
AOT11_05470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOT11_05470	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AOT11_05475	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AOT11_05480	COG4181	ATPase activity
AOT11_05490	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AOT11_05495	COG1716	ATPase activity
AOT11_05495	COG5001	Diguanylate cyclase
AOT11_05510	COG0484	heat shock protein binding
AOT11_05530	COG0583	DNA-binding transcription factor activity
AOT11_05535	COG0366	Alpha amylase catalytic
AOT11_05545	COG4533	DNA binding
AOT11_05555	COG2050	protein possibly involved in aromatic compounds catabolism
AOT11_05570	COG2067	long-chain fatty acid transport protein
AOT11_05575	COG2267	carboxylic ester hydrolase activity
AOT11_05600	COG0861	Integral membrane protein TerC family
AOT11_05605	COG0737	Belongs to the 5'-nucleotidase family
AOT11_05610	COG3593	DNA synthesis involved in DNA repair
AOT11_05620	COG0583	DNA-binding transcription factor activity
AOT11_05625	COG2116	formate transmembrane transporter activity
AOT11_05635	COG3038	cytochrome b561
AOT11_05650	COG0513	Belongs to the DEAD box helicase family
AOT11_05665	COG0546	phosphoglycolate phosphatase activity
AOT11_05670	COG3437	response regulator, receiver
AOT11_05670	COG0784	Response regulator, receiver
AOT11_05685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOT11_05695	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AOT11_05705	COG2207	Transcriptional regulator
AOT11_05710	COG1979	alcohol dehydrogenase
AOT11_05720	COG4191	Histidine kinase
AOT11_05725	COG1840	ABC-type Fe3 transport system, periplasmic component
AOT11_05730	COG2271	Major facilitator Superfamily
AOT11_05735	COG0469	pyruvate kinase activity
AOT11_05760	COG1609	Transcriptional regulator
AOT11_05765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOT11_05765	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOT11_05770	COG1105	Belongs to the carbohydrate kinase PfkB family
AOT11_05775	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AOT11_05775	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AOT11_05775	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AOT11_05820	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AOT11_05840	COG0556	nucleotide-excision repair
AOT11_05875	COG1132	(ABC) transporter
AOT11_05885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOT11_05900	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AOT11_05905	COG0583	DNA-binding transcription factor activity
AOT11_05925	COG2814	Major facilitator Superfamily
AOT11_05955	COG0641	radical SAM
AOT11_05965	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
AOT11_06000	COG0714	Associated with various cellular activities
AOT11_06020	COG3119	arylsulfatase activity
AOT11_06030	COG0513	Belongs to the DEAD box helicase family
AOT11_06035	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AOT11_06050	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AOT11_06080	COG1716	ATPase activity
AOT11_06080	COG5001	Diguanylate cyclase
AOT11_06090	COG0513	Belongs to the DEAD box helicase family
AOT11_06115	COG3005	denitrification pathway
AOT11_06120	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AOT11_06150	COG1879	ABC-type sugar transport system periplasmic component
AOT11_06160	COG0210	DNA helicase
AOT11_06165	COG1289	transmembrane transporter activity
AOT11_06195	COG0789	Transcriptional regulator
AOT11_06200	COG4604	ABC transporter, ATP-binding protein
AOT11_06205	COG4605	iron ion homeostasis
AOT11_06210	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOT11_06225	COG0110	maltose O-acetyltransferase activity
AOT11_06235	COG3290	protein histidine kinase activity
AOT11_06320	COG4964	Belongs to the GSP D family
AOT11_06340	COG0583	DNA-binding transcription factor activity
AOT11_06350	COG0419	ATPase involved in DNA repair
AOT11_06355	COG0420	3'-5' exonuclease activity
AOT11_06370	COG0456	acetyltransferase
AOT11_06380	COG0784	Response regulator, receiver
AOT11_06380	COG0835	chemotaxis
AOT11_06390	COG1609	Transcriptional regulator
AOT11_06395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOT11_06400	COG1879	ABC-type sugar transport system periplasmic component
AOT11_06405	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOT11_06410	COG1129	ABC transporter
AOT11_06430	COG2315	Protein conserved in bacteria
AOT11_06435	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AOT11_06450	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AOT11_06465	COG1288	antiporter activity
AOT11_06475	COG0671	phosphoesterase, PA-phosphatase related
AOT11_06490	COG2962	Rard protein
AOT11_06515	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AOT11_06520	COG0814	amino acid
AOT11_06545	COG3174	membrane
AOT11_06550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOT11_06585	COG0443	Heat shock 70 kDa protein
AOT11_06590	COG1454	alcohol dehydrogenase
AOT11_06600	COG2133	pyrroloquinoline quinone binding
AOT11_06605	COG1619	proteins homologs of microcin C7 resistance protein MccF
AOT11_06620	COG0247	lactate metabolic process
AOT11_06625	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
AOT11_06630	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AOT11_06660	COG3059	membrane
AOT11_06665	COG4175	Glycine betaine
AOT11_06690	COG1309	transcriptional regulator
AOT11_06710	COG1686	Belongs to the peptidase S11 family
AOT11_06730	COG1760	l-serine dehydratase
AOT11_06745	COG0583	DNA-binding transcription factor activity
AOT11_06750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOT11_06770	COG3842	ATPase activity
AOT11_06775	COG1840	ABC-type Fe3 transport system, periplasmic component
AOT11_06780	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AOT11_06795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOT11_06795	COG2207	Transcriptional regulator
AOT11_06800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOT11_06825	COG1011	Hydrolase
AOT11_06845	COG2171	N-acyltransferase activity
AOT11_06850	COG1765	OsmC-like protein
AOT11_06855	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOT11_06855	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOT11_06860	COG3706	GGDEF domain
AOT11_06875	COG0840	transmembrane signaling receptor activity
AOT11_06895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AOT11_06915	COG2084	Dehydrogenase
AOT11_06930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOT11_06935	COG0739	heme binding
AOT11_06970	COG0840	transmembrane signaling receptor activity
AOT11_06980	COG0366	Alpha amylase catalytic
AOT11_06985	COG0589	response to stress
AOT11_06990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOT11_06995	COG0835	chemotaxis
AOT11_06995	COG0784	Response regulator, receiver
AOT11_07005	COG0748	coenzyme F420 binding
AOT11_07010	COG3721	Heme iron utilization protein
AOT11_07020	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AOT11_07025	COG0811	peptide transport
AOT11_07030	COG0848	biopolymer transport protein
AOT11_07040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOT11_07045	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AOT11_07090	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AOT11_07095	COG0633	Ferredoxin
AOT11_07095	COG3217	Mosc domain protein beta barrel domain protein
AOT11_07095	COG0633	Ferredoxin
AOT11_07095	COG3217	Mosc domain protein beta barrel domain protein
AOT11_07100	COG0418	dihydroorotase activity
AOT11_07110	COG2354	Protein conserved in bacteria
AOT11_07165	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AOT11_07175	COG1596	polysaccharide export
AOT11_07260	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AOT11_07265	COG0602	queuosine metabolic process
AOT11_07270	COG0561	phosphatase activity
AOT11_07300	COG2828	Protein conserved in bacteria
AOT11_07305	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AOT11_07310	COG0372	Belongs to the citrate synthase family
AOT11_07315	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AOT11_07360	COG2197	response regulator
AOT11_07365	COG0730	response to heat
AOT11_07375	COG1653	transport
AOT11_07380	COG1175	transmembrane transport
AOT11_07385	COG0395	ABC-type sugar transport system, permease component
AOT11_07390	COG3842	ATPase activity
AOT11_07395	COG1349	DNA-binding transcription factor activity
AOT11_07400	COG0584	glycerophosphoryl diester phosphodiesterase
AOT11_07405	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AOT11_07415	COG1278	Cold shock
AOT11_07455	COG0625	glutathione transferase activity
AOT11_07465	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AOT11_07475	COG2195	Cleaves the N-terminal amino acid of tripeptides
AOT11_07480	COG0737	Belongs to the 5'-nucleotidase family
AOT11_07485	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AOT11_07490	COG3063	Type IV pilus biogenesis stability protein PilW
AOT11_07505	COG1451	nucleotide metabolic process
AOT11_07540	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AOT11_07580	COG0702	epimerase
AOT11_07585	COG2925	Exonuclease
AOT11_07590	COG1380	Effector of murein hydrolase LrgA
AOT11_07595	COG1346	cytolysis
AOT11_07620	COG1643	Atp-dependent helicase
AOT11_07625	COG0281	malic enzyme
AOT11_07630	COG2949	membrane
AOT11_07635	COG0471	metal ion transport
AOT11_07640	COG3706	GGDEF domain
AOT11_07640	COG0745	RESPONSE REGULATOR receiver
AOT11_07665	COG0492	ferredoxin-NADP+ reductase activity
AOT11_07670	COG4988	ABC transporter
AOT11_07675	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AOT11_07690	COG5002	protein histidine kinase activity
AOT11_07690	COG5002	protein histidine kinase activity
AOT11_07705	COG3070	regulator of competence-specific genes
AOT11_07715	COG2431	L-lysine efflux transmembrane transporter activity
AOT11_07725	COG0076	glutamate decarboxylase activity
AOT11_07730	COG1737	Transcriptional regulator
AOT11_07735	COG1979	alcohol dehydrogenase
AOT11_07740	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AOT11_07750	COG3273	potassium ion transport
AOT11_07750	COG2985	domain, Protein
AOT11_07760	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AOT11_07790	COG1136	(ABC) transporter
AOT11_07795	COG0702	epimerase
AOT11_07805	COG2814	Major facilitator Superfamily
AOT11_07815	COG1061	Type III restriction enzyme res subunit
AOT11_07825	COG0745	RESPONSE REGULATOR receiver
AOT11_07830	COG2205	protein histidine kinase activity
AOT11_07865	COG3313	Fe-S protein
AOT11_07875	COG4134	Bacterial extracellular solute-binding protein
AOT11_07880	COG4135	transport system, permease component
AOT11_07885	COG4136	ATPase activity
AOT11_07890	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AOT11_07895	COG3604	Transcriptional regulator
AOT11_07900	COG1151	hydroxylamine reductase activity
AOT11_07905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOT11_07910	COG0116	Belongs to the methyltransferase superfamily
AOT11_07910	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AOT11_07915	COG0564	pseudouridine synthase activity
AOT11_07925	COG0733	neurotransmitter:sodium symporter activity
AOT11_07935	COG0626	cystathionine gamma-synthase activity
AOT11_07940	COG2818	Glycosylase
AOT11_07960	COG1983	PspC domain protein
AOT11_07970	COG1842	Phage shock protein A
AOT11_07975	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AOT11_07985	COG4168	peptide transport system, permease
AOT11_07990	COG4171	peptide transport system, permease
AOT11_08000	COG4172	Belongs to the ABC transporter superfamily
AOT11_08015	COG1227	inorganic diphosphatase activity
AOT11_08045	COG0243	molybdopterin cofactor binding
AOT11_08050	COG3005	denitrification pathway
AOT11_08055	COG4459	periplasmic nitrate reductase
AOT11_08060	COG0390	transport system, permease component
AOT11_08065	COG2116	formate transmembrane transporter activity
AOT11_08085	COG0583	DNA-binding transcription factor activity
AOT11_08090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOT11_08100	COG1435	thymidine kinase activity
AOT11_08110	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AOT11_08115	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOT11_08120	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AOT11_08125	COG3012	SEC-C Motif Domain Protein
AOT11_08140	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AOT11_08145	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AOT11_08150	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AOT11_08150	COG0131	Imidazoleglycerol-phosphate dehydratase
AOT11_08155	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOT11_08160	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AOT11_08170	COG1757	Na H antiporter
AOT11_08175	COG2916	Histone family protein nucleoid-structuring protein H-NS
AOT11_08180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOT11_08190	COG0482	sulfurtransferase activity
AOT11_08200	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AOT11_08220	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AOT11_08235	COG1028	Short-chain dehydrogenase reductase Sdr
AOT11_08245	COG0501	Belongs to the peptidase M48B family
AOT11_08280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AOT11_08300	COG0686	Belongs to the AlaDH PNT family
AOT11_08310	COG0583	DNA-binding transcription factor activity
AOT11_08345	COG4166	transmembrane transport
AOT11_08350	COG4239	(ABC) transporter, permease
AOT11_08355	COG4174	ABC transporter (Permease)
AOT11_08360	COG0284	orotidine-5'-phosphate decarboxylase activity
AOT11_08365	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AOT11_08370	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AOT11_08380	COG0539	negative regulation of cytoplasmic translation
AOT11_08390	COG0616	signal peptide processing
AOT11_08395	COG1028	Short-chain dehydrogenase reductase Sdr
AOT11_08410	COG0587	DNA-directed DNA polymerase activity
AOT11_08415	COG0784	Response regulator, receiver
AOT11_08415	COG0835	chemotaxis
AOT11_08420	COG1940	carbohydrate kinase activity
AOT11_08425	COG0469	pyruvate kinase activity
AOT11_08430	COG4667	esterase of the alpha-beta hydrolase superfamily
AOT11_08440	COG0733	neurotransmitter:sodium symporter activity
AOT11_08450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AOT11_08450	COG1263	PTS System
AOT11_08455	COG0084	hydrolase, TatD family'
AOT11_08470	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AOT11_08500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOT11_08515	COG1399	metal-binding, possibly nucleic acid-binding protein
AOT11_08530	COG1530	ribonuclease E activity
AOT11_08535	COG0659	secondary active sulfate transmembrane transporter activity
AOT11_08540	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AOT11_08545	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AOT11_08560	COG0489	protein tyrosine kinase activity
AOT11_08565	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOT11_08565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOT11_08575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOT11_08580	COG1138	Cytochrome C-type biogenesis protein
AOT11_08585	COG3301	Polysulphide reductase, NrfD
AOT11_08590	COG0437	4 iron, 4 sulfur cluster binding
AOT11_08595	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AOT11_08630	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOT11_08635	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOT11_08700	COG0322	excinuclease ABC activity
AOT11_08705	COG2197	response regulator
AOT11_08710	COG0417	DNA replication proofreading
AOT11_08715	COG5001	Diguanylate cyclase
AOT11_08745	COG0009	L-threonylcarbamoyladenylate synthase
AOT11_08750	COG0613	PHP domain protein
AOT11_08760	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AOT11_08765	COG0512	Glutamine amidotransferase of anthranilate synthase
AOT11_08770	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AOT11_08775	COG0135	phosphoribosylanthranilate isomerase activity
AOT11_08775	COG0134	indole-3-glycerol-phosphate synthase activity
AOT11_08790	COG1301	dicarboxylic acid transport
AOT11_08805	COG1607	acyl-coa hydrolase
AOT11_08810	COG2350	Protein conserved in bacteria
AOT11_08820	COG0435	Glutathione S-transferase
AOT11_08830	COG0444	Belongs to the ABC transporter superfamily
AOT11_08835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOT11_08840	COG0601	transmembrane transport
AOT11_08850	COG0314	molybdopterin synthase activity
AOT11_08855	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AOT11_08860	COG0315	cyclic pyranopterin monophosphate synthase activity
AOT11_08875	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AOT11_08915	COG4656	Part of a membrane complex involved in electron transport
AOT11_08925	COG4659	FMN binding
AOT11_08935	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AOT11_08940	COG0346	lactoylglutathione lyase activity
AOT11_08950	COG2885	chlorophyll binding
AOT11_08955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AOT11_08960	COG2056	Na+-H+ antiporter family
AOT11_08970	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AOT11_08985	COG1028	Short-chain dehydrogenase reductase Sdr
AOT11_08995	COG1012	belongs to the aldehyde dehydrogenase family
AOT11_08995	COG1454	alcohol dehydrogenase
AOT11_09000	COG2095	MarC family integral membrane protein
AOT11_09005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOT11_09015	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AOT11_09020	COG1757	Na H antiporter
AOT11_09035	COG3081	Nucleoid-associated protein
AOT11_09040	COG3082	Protein of unknown function (DUF1414)
AOT11_09045	COG3083	sulfuric ester hydrolase activity
AOT11_09055	COG0569	domain protein
AOT11_09060	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AOT11_09065	COG2731	YhcH YjgK YiaL family protein
AOT11_09070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOT11_09075	COG3706	GGDEF domain
AOT11_09075	COG0745	RESPONSE REGULATOR receiver
AOT11_09085	COG0123	including yeast histone deacetylase and acetoin utilization protein
AOT11_09090	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AOT11_09095	COG0778	Nitroreductase
AOT11_09100	COG1902	pentaerythritol trinitrate reductase activity
AOT11_09100	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOT11_09105	COG0616	signal peptide processing
AOT11_09110	COG0252	asparaginase activity
AOT11_09115	COG3139	Protein of unknown function (DUF1315)
AOT11_09130	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AOT11_09135	COG0676	glucose-6-phosphate 1-epimerase activity
AOT11_09170	COG0330	HflC and HflK could
AOT11_09265	COG0732	type I restriction modification DNA specificity domain
AOT11_09330	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AOT11_09335	COG1946	Acyl-CoA thioesterase
AOT11_09345	COG1522	sequence-specific DNA binding
AOT11_09350	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOT11_09365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOT11_09435	COG0318	PFAM AMP-dependent synthetase and ligase
AOT11_09440	COG1441	menaquinone biosynthetic process
AOT11_09445	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AOT11_09450	COG0596	Alpha beta hydrolase
AOT11_09460	COG1169	isochorismate synthase
AOT11_09465	COG0436	Aminotransferase
AOT11_09470	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AOT11_09490	COG1555	photosystem II stabilization
AOT11_09495	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOT11_09500	COG0776	regulation of translation
AOT11_09505	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AOT11_09520	COG0544	peptidyl-prolyl cis-trans isomerase activity
AOT11_09525	COG4191	Histidine kinase
AOT11_09530	COG2204	response regulator
AOT11_09540	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AOT11_09545	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AOT11_09550	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AOT11_09560	COG3842	ATPase activity
AOT11_09585	COG0745	RESPONSE REGULATOR receiver
AOT11_09630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOT11_09635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOT11_09655	COG1216	Glycosyl transferase, family 2
AOT11_09660	COG2986	histidine ammonia-lyase
AOT11_09685	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOT11_09695	COG1028	Short-chain dehydrogenase reductase Sdr
AOT11_09710	COG5002	protein histidine kinase activity
AOT11_09715	COG0745	RESPONSE REGULATOR receiver
AOT11_09725	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AOT11_09735	COG2951	lytic endotransglycosylase activity
AOT11_09750	COG2894	cell division
AOT11_09760	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AOT11_09765	COG0318	PFAM AMP-dependent synthetase and ligase
AOT11_09770	COG0596	Alpha beta hydrolase
AOT11_09785	COG1214	PFAM Peptidase M22, glycoprotease
AOT11_09790	COG1199	ATP-dependent helicase activity
AOT11_09800	COG0788	formyltetrahydrofolate deformylase activity
AOT11_09805	COG3102	Protein conserved in bacteria
AOT11_09830	COG1918	ferrous iron import across plasma membrane
AOT11_09840	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AOT11_09850	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AOT11_09865	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOT11_09870	COG0567	Dehydrogenase, E1 component
AOT11_09880	COG1053	succinate dehydrogenase
AOT11_09885	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AOT11_09890	COG2009	succinate dehydrogenase
AOT11_09900	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AOT11_09910	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOT11_09920	COG0251	oxidation-reduction process
AOT11_09925	COG2964	Protein conserved in bacteria
AOT11_09930	COG0033	Phosphoglucomutase
AOT11_09935	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AOT11_09940	COG0596	Alpha beta hydrolase
AOT11_09950	COG0716	FMN binding
AOT11_09965	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AOT11_09970	COG1263	PTS System
AOT11_09970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AOT11_09970	COG2190	(PTS) system
AOT11_09975	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AOT11_09980	COG1940	carbohydrate kinase activity
AOT11_09980	COG1846	Transcriptional regulator
AOT11_09985	COG4651	solute:proton antiporter activity
AOT11_09985	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AOT11_09990	COG0367	asparagine synthase
AOT11_10000	COG3104	oligopeptide transport
AOT11_10020	COG0326	Molecular chaperone. Has ATPase activity
AOT11_10025	COG3710	Transcriptional regulator
AOT11_10045	COG0622	Phosphoesterase
AOT11_10070	COG1090	epimerase
AOT11_10075	COG0300	oxidoreductase activity
AOT11_10080	COG3118	belongs to the thioredoxin family
AOT11_10085	COG0330	HflC and HflK could
AOT11_10115	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AOT11_10120	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOT11_10125	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOT11_10130	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AOT11_10135	COG2190	(PTS) system
AOT11_10140	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AOT11_10145	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AOT11_10150	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AOT11_10155	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AOT11_10165	COG1705	Flagellar rod assembly protein muramidase FlgJ
AOT11_10165	COG3951	Flagellar rod assembly protein muramidase FlgJ
AOT11_10180	COG4786	Flagellar basal body rod
AOT11_10185	COG4787	bacterial-type flagellum-dependent cell motility
AOT11_10190	COG1749	Flagellar hook protein flgE
AOT11_10195	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AOT11_10200	COG1558	bacterial-type flagellum-dependent cell motility
AOT11_10205	COG1815	bacterial-type flagellum-dependent cell motility
AOT11_10210	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AOT11_10215	COG0784	Response regulator, receiver
AOT11_10215	COG0835	chemotaxis
AOT11_10275	COG2217	Heavy metal translocating P-type atpase
AOT11_10275	COG2608	mercury ion transmembrane transporter activity
AOT11_10290	COG3735	TraB family
AOT11_10305	COG2840	Smr protein MutS2
AOT11_10310	COG1187	pseudouridine synthase activity
AOT11_10330	COG2912	Transglutaminase-like superfamily
AOT11_10335	COG3094	Invasion gene expression up-regulator, SirB
AOT11_10340	COG2890	protein-(glutamine-N5) methyltransferase activity
AOT11_10355	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AOT11_10360	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AOT11_10455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOT11_10460	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AOT11_10465	COG1702	phosphate starvation-inducible protein PhoH
AOT11_10470	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AOT11_10475	COG4535	Mg2 and Co2 transporter CorC
AOT11_10485	COG2888	peptidyl-tyrosine sulfation
AOT11_10495	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AOT11_10500	COG1466	dna polymerase III delta subunit
AOT11_10505	COG0799	negative regulation of ribosome biogenesis
AOT11_10515	COG0768	penicillin binding
AOT11_10520	COG0772	Belongs to the SEDS family
AOT11_10525	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AOT11_10530	COG1686	Belongs to the peptidase S11 family
AOT11_10540	COG0321	lipoyl(octanoyl) transferase activity
AOT11_10585	COG0366	Alpha amylase catalytic
AOT11_10590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AOT11_10590	COG1263	PTS System
AOT11_10600	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AOT11_10605	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOT11_10610	COG2011	ABC-type metal ion transport system permease component
AOT11_10615	COG1464	Belongs to the NlpA lipoprotein family
AOT11_10620	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
AOT11_10640	COG3706	GGDEF domain
AOT11_10645	COG1611	Belongs to the LOG family
AOT11_10650	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AOT11_10665	COG2363	Small membrane protein
AOT11_10675	COG0583	DNA-binding transcription factor activity
AOT11_10690	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AOT11_10700	COG0142	geranyltranstransferase activity
AOT11_10710	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AOT11_10715	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AOT11_10740	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AOT11_10740	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AOT11_10745	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AOT11_10775	COG2252	PERMEase
AOT11_10780	COG2195	Cleaves the N-terminal amino acid of tripeptides
AOT11_10815	COG0590	tRNA wobble adenosine to inosine editing
AOT11_10820	COG0583	DNA-binding transcription factor activity
AOT11_10825	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AOT11_10830	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AOT11_10835	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AOT11_10905	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AOT11_10910	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AOT11_10915	COG0497	DNA recombination
AOT11_10920	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AOT11_10930	COG2867	negative regulation of translational initiation
AOT11_10980	COG0009	L-threonylcarbamoyladenylate synthase
AOT11_11000	COG0583	DNA-binding transcription factor activity
AOT11_11010	COG1115	amino acid carrier protein
AOT11_11015	COG1584	GPR1 FUN34 yaaH family protein
AOT11_11025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AOT11_11025	COG0519	Catalyzes the synthesis of GMP from XMP
AOT11_11030	COG0516	GMP reductase activity
AOT11_11030	COG0517	IMP dehydrogenase activity
AOT11_11035	COG1570	exodeoxyribonuclease VII activity
AOT11_11045	COG2203	Gaf domain
AOT11_11045	COG2199	diguanylate cyclase activity
AOT11_11060	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AOT11_11065	COG2976	Protein conserved in bacteria
AOT11_11100	COG2975	iron-sulfur cluster assembly
AOT11_11105	COG0633	Ferredoxin
AOT11_11110	COG0443	Heat shock 70 kDa protein
AOT11_11125	COG0822	iron-sulfur transferase activity
AOT11_11140	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AOT11_11145	COG0483	inositol monophosphate 1-phosphatase activity
AOT11_11150	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOT11_11155	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOT11_11160	COG1862	Preprotein translocase
AOT11_11170	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AOT11_11180	COG0517	IMP dehydrogenase activity
AOT11_11190	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AOT11_11195	COG0583	DNA-binding transcription factor activity
AOT11_11200	COG0450	alkyl hydroperoxide reductase
AOT11_11215	COG0704	Plays a role in the regulation of phosphate uptake
AOT11_11225	COG0581	inorganic phosphate transmembrane transporter activity
AOT11_11230	COG0573	inorganic phosphate transmembrane transporter activity
AOT11_11235	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AOT11_11240	COG0248	Ppx GppA phosphatase
AOT11_11250	COG5002	protein histidine kinase activity
AOT11_11255	COG0745	RESPONSE REGULATOR receiver
AOT11_11270	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AOT11_11325	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AOT11_11330	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AOT11_11335	COG0077	Prephenate dehydratase
AOT11_11335	COG1605	Chorismate mutase
AOT11_11340	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AOT11_11355	COG0488	(ABC) transporter
AOT11_11365	COG0739	heme binding
AOT11_11370	COG0287	Prephenate dehydrogenase
AOT11_11370	COG1605	Chorismate mutase
AOT11_11375	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AOT11_11380	COG1472	Belongs to the glycosyl hydrolase 3 family
AOT11_11385	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AOT11_11405	COG1966	Carbon starvation protein
AOT11_11410	COG3275	phosphorelay sensor kinase activity
AOT11_11425	COG1047	Peptidyl-prolyl cis-trans
AOT11_11435	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AOT11_11440	COG0196	riboflavin kinase activity
AOT11_11445	COG0728	peptidoglycan biosynthetic process
AOT11_11455	COG0640	Transcriptional regulator
AOT11_11460	COG0583	DNA-binding transcription factor activity
AOT11_11465	COG1283	sodium-dependent phosphate transmembrane transporter activity
AOT11_11545	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AOT11_11580	COG0730	response to heat
AOT11_11605	COG0667	Aldo Keto reductase
AOT11_11625	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AOT11_11630	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AOT11_11635	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AOT11_11640	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOT11_11650	COG0716	FMN binding
AOT11_11665	COG0513	Belongs to the DEAD box helicase family
AOT11_11670	COG3022	response to hydroperoxide
AOT11_11675	COG1115	amino acid carrier protein
AOT11_11705	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AOT11_11735	COG0745	RESPONSE REGULATOR receiver
AOT11_11745	COG0784	Response regulator, receiver
AOT11_11745	COG5002	protein histidine kinase activity
AOT11_11745	COG2198	Histidine kinase
AOT11_11750	COG3706	GGDEF domain
AOT11_11750	COG2203	Gaf domain
AOT11_11750	COG5001	Diguanylate cyclase
AOT11_11750	COG4251	negative regulation of phosphorylation
AOT11_11755	COG1242	4 iron, 4 sulfur cluster binding
AOT11_11760	COG0067	glutamate synthase
AOT11_11760	COG0069	glutamate synthase activity
AOT11_11760	COG0070	glutamate synthase
AOT11_11770	COG0067	glutamate synthase
AOT11_11770	COG0069	glutamate synthase activity
AOT11_11770	COG0070	glutamate synthase
AOT11_11775	COG0493	'glutamate synthase
AOT11_11785	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AOT11_11800	COG2860	membrane
AOT11_11805	COG0583	DNA-binding transcription factor activity
AOT11_11810	COG0730	response to heat
AOT11_11830	COG0505	Belongs to the CarA family
AOT11_11840	COG0494	nUDIX hydrolase
AOT11_11845	COG0653	protein targeting
AOT11_11860	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AOT11_11865	COG0849	cell division
AOT11_11870	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AOT11_11875	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AOT11_11885	COG0772	Belongs to the SEDS family
AOT11_11895	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AOT11_11900	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AOT11_11910	COG0768	penicillin binding
AOT11_11915	COG3116	cell division
AOT11_11925	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AOT11_11930	COG3107	peptidoglycan biosynthetic process
AOT11_11940	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AOT11_11945	COG2823	Periplasmic or secreted lipoprotein
AOT11_11950	COG2969	positive regulation of protein catabolic process
AOT11_11955	COG0625	glutathione transferase activity
AOT11_11960	COG2857	Cytochrome c1
AOT11_11965	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AOT11_11970	COG0723	plastoquinol--plastocyanin reductase activity
AOT11_11985	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AOT11_11990	COG3105	Protein conserved in bacteria
AOT11_11995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOT11_12000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOT11_12010	COG0187	DNA topoisomerase II activity
AOT11_12015	COG3150	esterase
AOT11_12025	COG3151	Protein conserved in bacteria
AOT11_12030	COG0494	nUDIX hydrolase
AOT11_12035	COG1538	Outer membrane efflux protein
AOT11_12045	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AOT11_12055	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AOT11_12060	COG3025	triphosphatase activity
AOT11_12065	COG1392	Phosphate transport regulator
AOT11_12070	COG0306	phosphate transporter
AOT11_12075	COG4991	sh3 domain protein
AOT11_12080	COG3409	Peptidoglycan-binding domain 1 protein
AOT11_12080	COG3267	Type II secretory pathway component ExeA
AOT11_12085	COG0617	tRNA 3'-terminal CCA addition
AOT11_12095	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AOT11_12100	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AOT11_12110	COG0596	Alpha beta hydrolase
AOT11_12120	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AOT11_12125	COG1610	YqeY-like protein
AOT11_12135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AOT11_12150	COG3550	peptidyl-serine autophosphorylation
AOT11_12165	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AOT11_12170	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AOT11_12175	COG1349	DNA-binding transcription factor activity
AOT11_12180	COG0469	pyruvate kinase activity
AOT11_12190	COG3706	GGDEF domain
AOT11_12195	COG0440	acetolactate synthase activity
AOT11_12200	COG0028	Belongs to the TPP enzyme family
AOT11_12205	COG1022	Amp-dependent synthetase and ligase
AOT11_12235	COG0473	3-isopropylmalate dehydrogenase activity
AOT11_12245	COG0066	3-isopropylmalate dehydratase activity
AOT11_12270	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AOT11_12295	COG3610	response to peptide
AOT11_12300	COG2966	Psort location CytoplasmicMembrane, score
AOT11_12315	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AOT11_12320	COG0142	geranyltranstransferase activity
AOT11_12325	COG0039	L-malate dehydrogenase activity
AOT11_12345	COG0589	response to stress
AOT11_12355	COG0204	Acyl-transferase
AOT11_12365	COG5007	Belongs to the BolA IbaG family
AOT11_12375	COG2854	intermembrane phospholipid transfer
AOT11_12380	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AOT11_12385	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AOT11_12390	COG1127	ABC transporter
AOT11_12400	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AOT11_12400	COG0517	IMP dehydrogenase activity
AOT11_12405	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AOT11_12415	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AOT11_12420	COG1137	ATPase activity
AOT11_12430	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AOT11_12435	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOT11_12440	COG1660	Displays ATPase and GTPase activities
AOT11_12445	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOT11_12450	COG2239	Acts as a magnesium transporter
AOT11_12455	COG0312	modulator of DNA gyrase
AOT11_12460	COG3028	Belongs to the UPF0307 family
AOT11_12470	COG1178	ABC-type Fe3 transport system permease component
AOT11_12475	COG4143	(ABC) transporter
AOT11_12480	COG0163	prenyltransferase activity
AOT11_12485	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AOT11_12505	COG2105	PFAM AIG2 family protein
AOT11_12510	COG2911	Protein conserved in bacteria
AOT11_12515	COG0729	surface antigen
AOT11_12530	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AOT11_12545	COG1136	(ABC) transporter
AOT11_12545	COG0577	efflux transmembrane transporter activity
AOT11_12570	COG0471	metal ion transport
AOT11_12570	COG3273	potassium ion transport
AOT11_12575	COG2895	sulfate adenylyltransferase (ATP) activity
AOT11_12585	COG1648	precorrin-2 dehydrogenase activity
AOT11_12585	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AOT11_12590	COG0737	Belongs to the 5'-nucleotidase family
AOT11_12600	COG2153	protein acetylation
AOT11_12610	COG3061	Opacity-associated protein A
AOT11_12610	COG3266	domain, Protein
AOT11_12615	COG0545	Peptidyl-prolyl cis-trans isomerase
AOT11_12640	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AOT11_12655	COG0201	protein transport
AOT11_12710	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AOT11_12755	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AOT11_12790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AOT11_12795	COG5433	transposase activity
AOT11_12830	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AOT11_12835	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AOT11_12905	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AOT11_12920	COG0859	PFAM glycosyl transferase family 9
AOT11_12925	COG1519	Transferase
AOT11_12945	COG2089	acid synthase
AOT11_12965	COG1083	cytidylyl-transferase
AOT11_12970	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AOT11_12975	COG1086	Polysaccharide biosynthesis protein
AOT11_13005	COG3083	sulfuric ester hydrolase activity
AOT11_13010	COG3642	lipopolysaccharide core region biosynthetic process
AOT11_13015	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AOT11_13020	COG0859	PFAM glycosyl transferase family 9
AOT11_13025	COG0463	Glycosyl transferase, family 2
AOT11_13030	COG0859	PFAM glycosyl transferase family 9
AOT11_13065	COG2003	Belongs to the UPF0758 family
AOT11_13070	COG0840	transmembrane signaling receptor activity
AOT11_13085	COG1560	Kdo2-lipid A biosynthetic process
AOT11_13100	COG1561	YicC-like family, N-terminal region
AOT11_13115	COG0653	protein targeting
AOT11_13135	COG0747	negative chemotaxis
AOT11_13140	COG4239	(ABC) transporter, permease
AOT11_13145	COG4174	ABC transporter (Permease)
AOT11_13150	COG4206	TonB-dependent receptor
AOT11_13160	COG0811	peptide transport
AOT11_13165	COG0811	peptide transport
AOT11_13170	COG0848	biopolymer transport protein
AOT11_13195	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AOT11_13200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOT11_13205	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AOT11_13210	COG2233	PERMEase
AOT11_13215	COG2205	protein histidine kinase activity
AOT11_13220	COG0745	RESPONSE REGULATOR receiver
AOT11_13230	COG2183	response to ionizing radiation
AOT11_13240	COG0596	Alpha beta hydrolase
AOT11_13255	COG0494	nUDIX hydrolase
AOT11_13260	COG1218	3'(2'),5'-bisphosphate nucleotidase
AOT11_13270	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AOT11_13275	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AOT11_13280	COG3156	type II secretion system protein K
AOT11_13285	COG4795	General secretion pathway protein
AOT11_13290	COG2165	general secretion pathway protein
AOT11_13295	COG2165	general secretion pathway protein
AOT11_13300	COG2165	general secretion pathway protein
AOT11_13305	COG1459	type II secretion system
AOT11_13310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AOT11_13320	COG3031	protein transport across the cell outer membrane
AOT11_13325	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AOT11_13345	COG0456	acetyltransferase
AOT11_13355	COG1295	ribonuclease BN
AOT11_13375	COG0174	glutamine synthetase
AOT11_13385	COG3852	Histidine kinase
AOT11_13390	COG2204	response regulator
AOT11_13395	COG5001	Diguanylate cyclase
AOT11_13395	COG3300	MHYT domain
AOT11_13400	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AOT11_13425	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AOT11_13430	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AOT11_13430	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AOT11_13440	COG0084	hydrolase, TatD family'
AOT11_13445	COG0805	protein transport
AOT11_13455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AOT11_13465	COG3165	ubiquinone biosynthetic process from chorismate
AOT11_13475	COG1322	Protein conserved in bacteria
AOT11_13565	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AOT11_13570	COG3118	belongs to the thioredoxin family
AOT11_13585	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AOT11_13595	COG0514	ATP-dependent DNA helicase (RecQ)
AOT11_13600	COG2962	Rard protein
AOT11_13610	COG1280	lysine exporter protein (LysE YggA)
AOT11_13615	COG0210	DNA helicase
AOT11_13655	COG0006	proline dipeptidase activity
AOT11_13655	COG0006	proline dipeptidase activity
AOT11_13675	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AOT11_13680	COG0352	thiamine-phosphate diphosphorylase activity
AOT11_13695	COG2132	Multicopper oxidase
AOT11_13745	COG0582	viral genome integration into host DNA
AOT11_13795	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AOT11_13800	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AOT11_13805	COG1739	Uncharacterized protein family UPF0029
AOT11_13815	COG0183	Belongs to the thiolase family
AOT11_13820	COG0604	alcohol dehydrogenase
AOT11_13845	COG2119	membrane
AOT11_13855	COG0751	glycine-tRNA ligase activity
AOT11_13865	COG3977	Valine--pyruvate aminotransferase
AOT11_13875	COG0071	Belongs to the small heat shock protein (HSP20) family
AOT11_13880	COG0187	DNA topoisomerase II activity
AOT11_13890	COG0592	DNA-directed DNA polymerase activity
AOT11_13910	COG1126	abc transporter atp-binding protein
AOT11_13925	COG0706	membrane insertase activity
AOT11_13935	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AOT11_13940	COG0445	tRNA wobble uridine modification
AOT11_13950	COG1192	Involved in chromosome partitioning
AOT11_13955	COG1475	DNA binding
AOT11_13960	COG3312	ion transport
AOT11_14010	COG0765	amino acid transport
AOT11_14020	COG2814	Major facilitator Superfamily
AOT11_14025	COG0583	DNA-binding transcription factor activity
AOT11_14035	COG0129	dihydroxy-acid dehydratase activity
AOT11_14040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AOT11_14045	COG3978	acetolactate synthase activity
AOT11_14055	COG0606	chelatase, subunit chli
AOT11_14065	COG0204	Acyl-transferase
AOT11_14070	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOT11_14075	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AOT11_14085	COG3084	Protein conserved in bacteria
AOT11_14090	COG4326	sporulation control protein
AOT11_14095	COG1272	protein, Hemolysin III
AOT11_14100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AOT11_14105	COG0569	domain protein
AOT11_14110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AOT11_14110	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AOT11_14115	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AOT11_14130	COG0758	DNA mediated transformation
AOT11_14140	COG0551	DNA topoisomerase type I activity
AOT11_14165	COG0408	coproporphyrinogen oxidase activity
AOT11_14170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AOT11_14180	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AOT11_14215	COG0583	DNA-binding transcription factor activity
AOT11_14225	COG2960	long-chain fatty acid transporting porin activity
AOT11_14230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOT11_14235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOT11_14240	COG1309	transcriptional regulator
AOT11_14280	COG4172	Belongs to the ABC transporter superfamily
AOT11_14285	COG4166	transmembrane transport
AOT11_14295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOT11_14330	COG2815	serine threonine protein kinase
AOT11_14330	COG0515	serine threonine protein kinase
AOT11_14345	COG1609	Transcriptional regulator
AOT11_14350	COG0129	dihydroxy-acid dehydratase activity
AOT11_14355	COG3265	gluconokinase activity
AOT11_14360	COG2610	gluconate transmembrane transporter activity
AOT11_14365	COG0800	Aldolase
AOT11_14375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOT11_14380	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AOT11_14390	COG1522	sequence-specific DNA binding
AOT11_14395	COG5002	protein histidine kinase activity
AOT11_14395	COG5001	Diguanylate cyclase
AOT11_14400	COG0742	ribosomal rna small subunit methyltransferase
AOT11_14415	COG0589	response to stress
AOT11_14420	COG1528	Iron-storage protein
AOT11_14430	COG2081	HI0933 family
AOT11_14440	COG2959	enzyme of heme biosynthesis
AOT11_14455	COG3072	Adenylate cyclase
AOT11_14470	COG0019	diaminopimelate decarboxylase activity
AOT11_14490	COG1011	Hydrolase
AOT11_14495	COG3287	FIST C domain
AOT11_14495	COG2200	EAL domain
AOT11_14495	COG2199	diguanylate cyclase activity
AOT11_14515	COG0561	phosphatase activity
AOT11_14520	COG2267	carboxylic ester hydrolase activity
AOT11_14525	COG1280	lysine exporter protein (LysE YggA)
AOT11_14530	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AOT11_14535	COG0640	Transcriptional regulator
AOT11_14540	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AOT11_14580	COG2095	MarC family integral membrane protein
AOT11_14590	COG0742	ribosomal rna small subunit methyltransferase
AOT11_14595	COG0552	protein localization to endoplasmic reticulum
AOT11_14600	COG2884	Cell division ATP-binding protein ftsE
AOT11_14605	COG2177	Part of the ABC transporter FtsEX involved in
AOT11_14620	COG0705	Rhomboid family
AOT11_14625	COG1580	Controls the rotational direction of flagella during chemotaxis
AOT11_14630	COG3161	chorismate lyase activity
AOT11_14640	COG2937	Belongs to the GPAT DAPAT family
AOT11_14675	COG4206	TonB-dependent receptor
AOT11_14765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOT11_14775	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AOT11_14780	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AOT11_14780	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AOT11_14815	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AOT11_14855	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AOT11_14885	COG1573	uracil-dna glycosylase
AOT11_14895	COG3068	Protein conserved in bacteria
AOT11_14900	COG1253	flavin adenine dinucleotide binding
AOT11_14925	COG0789	Transcriptional regulator
AOT11_14930	COG0840	transmembrane signaling receptor activity
AOT11_14935	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AOT11_14945	COG2264	protein methyltransferase activity
AOT11_14950	COG0439	Biotin carboxylase
AOT11_14955	COG0511	ligase activity, forming carbon-carbon bonds
AOT11_14965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOT11_14980	COG2814	Major facilitator Superfamily
AOT11_14985	COG2205	protein histidine kinase activity
AOT11_14985	COG0784	Response regulator, receiver
AOT11_14985	COG2198	Histidine kinase
AOT11_15000	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOT11_15010	COG2095	MarC family integral membrane protein
AOT11_15020	COG4232	protein-disulfide reductase activity
AOT11_15025	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AOT11_15030	COG1027	Aspartate ammonia-lyase
AOT11_15040	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AOT11_15045	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AOT11_15050	COG2205	protein histidine kinase activity
AOT11_15055	COG0745	RESPONSE REGULATOR receiver
AOT11_15060	COG3678	ATP-independent chaperone mediated protein folding
AOT11_15075	COG0534	Mate efflux family protein
AOT11_15095	COG1285	pathogenesis
AOT11_15100	COG1509	lysine 2,3-aminomutase activity
AOT11_15120	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AOT11_15130	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AOT11_15135	COG1053	succinate dehydrogenase
AOT11_15160	COG4942	peptidase
AOT11_15165	COG1045	serine acetyltransferase
AOT11_15180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOT11_15185	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AOT11_15195	COG0471	metal ion transport
AOT11_15255	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AOT11_15260	COG0802	atpase or kinase
AOT11_15265	COG0860	N-Acetylmuramoyl-L-alanine amidase
AOT11_15270	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AOT11_15285	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AOT11_15290	COG0330	HflC and HflK could
AOT11_15295	COG0330	HflC and HflK could
AOT11_15300	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AOT11_15305	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AOT11_15310	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AOT11_15325	COG0402	S-adenosylhomocysteine deaminase activity
AOT11_15330	COG0557	exoribonuclease II activity
AOT11_15340	COG0546	phosphoglycolate phosphatase activity
AOT11_15345	COG0180	Tryptophanyl-tRNA synthetase
AOT11_15365	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOT11_15375	COG1012	belongs to the aldehyde dehydrogenase family
AOT11_15385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOT11_15390	COG3954	Phosphoribulokinase
AOT11_15400	COG0429	hydrolase of the alpha beta-hydrolase fold
AOT11_15410	COG0488	(ABC) transporter
AOT11_15415	COG2249	NAD(P)H dehydrogenase (quinone) activity
AOT11_15430	COG1047	Peptidyl-prolyl cis-trans
AOT11_15450	COG0545	Peptidyl-prolyl cis-trans isomerase
AOT11_15455	COG2964	Protein conserved in bacteria
AOT11_15460	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AOT11_15485	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AOT11_15495	COG2906	2 iron, 2 sulfur cluster binding
AOT11_15505	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOT11_15535	COG1494	fructose-1,6-bisphosphatase
AOT11_15550	COG1575	Belongs to the MenA family. Type 1 subfamily
AOT11_15570	COG1609	Transcriptional regulator
AOT11_15575	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AOT11_15585	COG0281	malic enzyme
AOT11_15595	COG0626	cystathionine gamma-synthase activity
AOT11_15600	COG0460	homoserine dehydrogenase
AOT11_15600	COG0527	aspartate kinase activity
AOT11_15605	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AOT11_15615	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AOT11_15620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOT11_15625	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AOT11_15655	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AOT11_15700	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AOT11_15705	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AOT11_15735	COG0305	Participates in initiation and elongation during chromosome replication
AOT11_15740	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AOT11_15750	COG0432	Pfam Uncharacterised protein family UPF0047
AOT11_15765	COG0735	belongs to the Fur family
AOT11_15795	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOT11_15880	COG3706	GGDEF domain
AOT11_15880	COG0745	RESPONSE REGULATOR receiver
AOT11_15890	COG1410	methionine synthase
AOT11_15890	COG0646	methionine synthase
AOT11_15895	COG0527	aspartate kinase activity
AOT11_15900	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AOT11_15930	COG2200	EAL domain
AOT11_15930	COG2199	diguanylate cyclase activity
AOT11_15955	COG3409	Peptidoglycan-binding domain 1 protein
AOT11_15955	COG3267	Type II secretory pathway component ExeA
AOT11_15965	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AOT11_15970	COG1459	type II secretion system
AOT11_16015	COG1077	Cell shape determining protein MreB Mrl
AOT11_16020	COG1792	Involved in formation and maintenance of cell shape
AOT11_16025	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AOT11_16035	COG1530	ribonuclease E activity
AOT11_16040	COG3164	Protein of unknown function
AOT11_16045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOT11_16050	COG0312	modulator of DNA gyrase
AOT11_16055	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AOT11_16060	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AOT11_16070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AOT11_16075	COG0251	oxidation-reduction process
AOT11_16110	COG0456	acetyltransferase
AOT11_16120	COG4269	membrane
AOT11_16135	COG2927	DNA polymerase III (CHI subunit)
AOT11_16145	COG0795	lipopolysaccharide-transporting ATPase activity
AOT11_16150	COG0795	lipopolysaccharide-transporting ATPase activity
AOT11_16165	COG0726	polysaccharide deacetylase
AOT11_16170	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AOT11_16180	COG1447	Phosphotransferase system cellobiose-specific component IIA
AOT11_16185	COG1486	melibiose metabolic process
AOT11_16190	COG3394	polysaccharide catabolic process
AOT11_16195	COG1609	Transcriptional regulator
AOT11_16290	COG0840	transmembrane signaling receptor activity
AOT11_16310	COG0741	lytic transglycosylase activity
AOT11_16335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AOT11_16355	COG0762	integral membrane protein
AOT11_16360	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AOT11_16365	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AOT11_16395	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AOT11_16405	COG2356	endonuclease I
AOT11_16425	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AOT11_16435	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AOT11_16445	COG0191	fructose-bisphosphate aldolase activity
AOT11_16450	COG0668	transmembrane transport
AOT11_16455	COG1279	arginine transmembrane transporter activity
AOT11_16470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOT11_16480	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AOT11_16485	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AOT11_16490	COG3079	Belongs to the UPF0149 family
AOT11_16495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOT11_16500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOT11_16515	COG0354	folic acid binding
AOT11_16530	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AOT11_16535	COG1595	DNA-templated transcription, initiation
AOT11_16550	COG3086	response to oxidative stress
AOT11_16560	COG0681	Belongs to the peptidase S26 family
AOT11_16575	COG1381	Involved in DNA repair and RecF pathway recombination
AOT11_16585	COG0736	holo-[acyl-carrier-protein] synthase activity
AOT11_16605	COG2205	protein histidine kinase activity
AOT11_16605	COG3437	response regulator, receiver
AOT11_16605	COG3850	Histidine kinase
AOT11_16605	COG4999	Histidine kinase
AOT11_16610	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AOT11_16615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AOT11_16620	COG3956	TIGRFAM MazG family protein
AOT11_16660	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AOT11_16665	COG0585	pseudouridine synthase activity
AOT11_16680	COG1388	LysM domain
AOT11_16680	COG4942	peptidase
AOT11_16685	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AOT11_16690	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AOT11_16710	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AOT11_16715	COG0527	aspartate kinase activity
AOT11_16770	COG5016	pyruvate
AOT11_16770	COG0511	ligase activity, forming carbon-carbon bonds
AOT11_16775	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AOT11_16785	COG1238	metal cluster binding
AOT11_16790	COG0612	Peptidase, M16
AOT11_16810	COG4536	flavin adenine dinucleotide binding
AOT11_16815	COG4137	Cytochrome C assembly protein
AOT11_16820	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AOT11_16845	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AOT11_16855	COG0237	dephospho-CoA kinase activity
AOT11_16865	COG1459	type II secretion system
AOT11_16870	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AOT11_16885	COG3023	N-Acetylmuramoyl-L-alanine amidase
AOT11_16890	COG2186	Transcriptional regulator
AOT11_16895	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AOT11_16900	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOT11_16905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOT11_16920	COG0288	reversible hydration of carbon dioxide
AOT11_16925	COG0659	secondary active sulfate transmembrane transporter activity
AOT11_16930	COG1131	(ABC) transporter
AOT11_16935	COG0842	Transport permease protein
AOT11_16950	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AOT11_16965	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AOT11_16970	COG1489	DNA binding
AOT11_16975	COG1643	Atp-dependent helicase
AOT11_16980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOT11_16985	COG1752	Esterase of the alpha-beta hydrolase superfamily
AOT11_16990	COG1049	propionate catabolic process, 2-methylcitrate cycle
AOT11_16995	COG1929	Belongs to the glycerate kinase type-1 family
AOT11_17000	COG2610	gluconate transmembrane transporter activity
AOT11_17005	COG3835	regulator
AOT11_17015	COG0347	Belongs to the P(II) protein family
AOT11_17020	COG0004	ammonium transporteR
AOT11_17025	COG1840	ABC-type Fe3 transport system, periplasmic component
AOT11_17035	COG3842	ATPase activity
AOT11_17040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOT11_17055	COG2971	BadF BadG BcrA BcrD
AOT11_17065	COG4608	Belongs to the ABC transporter superfamily
AOT11_17070	COG0444	Belongs to the ABC transporter superfamily
AOT11_17075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOT11_17080	COG0601	transmembrane transport
AOT11_17085	COG0747	negative chemotaxis
AOT11_17090	COG2205	protein histidine kinase activity
AOT11_17090	COG0784	Response regulator, receiver
AOT11_17100	COG0628	permease
AOT11_17125	COG0739	heme binding
AOT11_17140	COG2832	Protein of unknown function (DUF454)
AOT11_17145	COG2027	D-alanyl-D-alanine carboxypeptidase
AOT11_17160	COG1534	Rna-binding protein
AOT11_17170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOT11_17175	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AOT11_17185	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AOT11_17205	COG0195	Participates in both transcription termination and antitermination
AOT11_17250	COG4785	May be involved in cell division
AOT11_17260	COG0534	Mate efflux family protein
AOT11_17285	COG3153	acetyltransferase
AOT11_17295	COG0456	acetyltransferase
AOT11_17305	COG3706	GGDEF domain
AOT11_17315	COG0084	hydrolase, TatD family'
AOT11_17320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AOT11_17325	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AOT11_17350	COG0560	Phosphoserine phosphatase
AOT11_17360	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AOT11_17380	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AOT11_17385	COG1022	Amp-dependent synthetase and ligase
AOT11_17420	COG4964	Belongs to the GSP D family
AOT11_17475	COG2059	Chromate
AOT11_17480	COG0583	DNA-binding transcription factor activity
AOT11_17490	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AOT11_17490	COG3408	Glycogen debranching enzyme
AOT11_17495	COG0531	amino acid
AOT11_17500	COG0531	amino acid
AOT11_17505	COG2731	YhcH YjgK YiaL family protein
AOT11_17510	COG3250	beta-galactosidase activity
AOT11_17520	COG1609	Transcriptional regulator
AOT11_17525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOT11_17535	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AOT11_17540	COG2017	converts alpha-aldose to the beta-anomer
AOT11_17545	COG0840	transmembrane signaling receptor activity
AOT11_17555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOT11_17570	COG0189	ligase activity
AOT11_17570	COG0569	domain protein
AOT11_17585	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AOT11_17590	COG1349	DNA-binding transcription factor activity
AOT11_17600	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AOT11_17605	COG2171	N-acyltransferase activity
AOT11_17610	COG3141	response to X-ray
AOT11_17625	COG3083	sulfuric ester hydrolase activity
AOT11_17630	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AOT11_17635	COG1074	ATP-dependent DNA helicase activity
AOT11_17640	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AOT11_17660	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AOT11_17665	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AOT11_17670	COG2166	iron-sulfur cluster assembly
AOT11_17675	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AOT11_17680	COG0693	protein deglycase activity
AOT11_17685	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AOT11_17700	COG1595	DNA-templated transcription, initiation
AOT11_17710	COG2211	Major facilitator Superfamily
AOT11_17730	COG0271	Belongs to the BolA IbaG family
AOT11_17765	COG1477	protein flavinylation
AOT11_17775	COG3706	GGDEF domain
AOT11_17775	COG0745	RESPONSE REGULATOR receiver
AOT11_17785	COG0514	ATP-dependent DNA helicase (RecQ)
AOT11_17800	COG0733	neurotransmitter:sodium symporter activity
AOT11_17825	COG1720	tRNA m6t6A37 methyltransferase activity
AOT11_17830	COG0254	rRNA binding
AOT11_17840	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AOT11_17845	COG1671	Belongs to the UPF0178 family
AOT11_17875	COG3098	single-species biofilm formation
AOT11_17890	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AOT11_17900	COG0024	Methionine aminopeptidase
AOT11_17920	COG0233	cytoplasmic translational termination
AOT11_17930	COG0575	Belongs to the CDS family
AOT11_17940	COG0750	zinc metalloprotease
AOT11_17945	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AOT11_17950	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AOT11_17955	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOT11_17980	COG0587	DNA-directed DNA polymerase activity
AOT11_18000	COG0347	Belongs to the P(II) protein family
AOT11_18005	COG3021	interspecies interaction between organisms
AOT11_18015	COG0741	lytic transglycosylase activity
AOT11_18015	COG1388	LysM domain
AOT11_18020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOT11_18025	COG2226	methyltransferase
AOT11_18035	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AOT11_18045	COG2249	NAD(P)H dehydrogenase (quinone) activity
AOT11_18065	COG1960	acyl-CoA dehydrogenase activity
AOT11_18075	COG0121	glutamine amidotransferase
AOT11_18080	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AOT11_18090	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AOT11_18095	COG2233	PERMEase
AOT11_18115	COG1393	Belongs to the ArsC family
AOT11_18120	COG4783	chaperone-mediated protein folding
AOT11_18135	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AOT11_18140	COG2716	regulation of RNA biosynthetic process
AOT11_18145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOT11_18170	COG1393	Belongs to the ArsC family
AOT11_18195	COG2837	iron assimilation
AOT11_18200	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AOT11_18205	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AOT11_18210	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AOT11_18215	COG1334	flagellar protein FlaG
AOT11_18220	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AOT11_18230	COG1516	flagellar protein fliS
AOT11_18235	COG2204	response regulator
AOT11_18240	COG4191	Histidine kinase
AOT11_18245	COG2204	response regulator
AOT11_18250	COG1677	Flagellar hook-basal body complex protein FliE
AOT11_18260	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AOT11_18310	COG1987	bacterial-type flagellum assembly
AOT11_18315	COG1684	flagellar biosynthetic protein fliR
AOT11_18335	COG0455	bacterial-type flagellum organization
AOT11_18350	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AOT11_18355	COG2198	Histidine kinase
AOT11_18355	COG0643	Histidine kinase
AOT11_18365	COG1192	Involved in chromosome partitioning
AOT11_18375	COG0835	chemotaxis
AOT11_18385	COG4133	protoheme IX ABC transporter activity
AOT11_18390	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AOT11_18395	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AOT11_18400	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AOT11_18410	COG1138	Cytochrome C-type biogenesis protein
AOT11_18415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOT11_18420	COG3088	subunit of a heme lyase
AOT11_18420	COG4235	cytochrome complex assembly
AOT11_18430	COG2853	Lipoprotein
AOT11_18435	COG2067	long-chain fatty acid transport protein
AOT11_18440	COG2067	long-chain fatty acid transport protein
AOT11_18465	COG1025	Belongs to the peptidase M16 family
AOT11_18470	COG2062	phosphohistidine phosphatase, SixA
AOT11_18475	COG2840	Smr protein MutS2
AOT11_18480	COG2890	protein-(glutamine-N5) methyltransferase activity
AOT11_18490	COG2860	membrane
AOT11_18495	COG3101	peptidyl-lysine hydroxylation
AOT11_18510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOT11_18520	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AOT11_18540	COG0285	dihydrofolate synthase activity
AOT11_18545	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AOT11_18550	COG1286	toxin biosynthetic process
AOT11_18555	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AOT11_18560	COG0583	DNA-binding transcription factor activity
AOT11_18565	COG0745	RESPONSE REGULATOR receiver
AOT11_18580	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AOT11_18600	COG2205	protein histidine kinase activity
AOT11_18605	COG0745	RESPONSE REGULATOR receiver
AOT11_18610	COG0814	amino acid
AOT11_18615	COG0251	oxidation-reduction process
AOT11_18625	COG2964	Protein conserved in bacteria
AOT11_18635	COG2983	Belongs to the UPF0260 family
AOT11_18645	COG0346	lactoylglutathione lyase activity
AOT11_18655	COG1785	Belongs to the alkaline phosphatase family
AOT11_18670	COG2226	methyltransferase
AOT11_18740	COG1396	sequence-specific DNA binding
AOT11_18745	COG3550	peptidyl-serine autophosphorylation
AOT11_18750	COG0582	viral genome integration into host DNA
AOT11_18760	COG2199	diguanylate cyclase activity
AOT11_18760	COG2203	Gaf domain
AOT11_18780	COG3710	Transcriptional regulator
AOT11_18785	COG0531	amino acid
AOT11_18790	COG1982	Orn Lys Arg decarboxylase major
AOT11_18795	COG3706	GGDEF domain
AOT11_18800	COG4109	DRTGG domain
AOT11_18825	COG0537	adenosine 5'-monophosphoramidase activity
AOT11_18855	COG1252	NADH dehydrogenase
AOT11_18870	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AOT11_18880	COG4591	ABC-type transport system involved in lipoprotein release permease component
AOT11_18890	COG4591	ABC-type transport system involved in lipoprotein release permease component
AOT11_18900	COG2333	competence protein COMEC
AOT11_18900	COG0658	competence protein
AOT11_18910	COG1663	tetraacyldisaccharide 4'-kinase activity
AOT11_18920	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AOT11_18925	COG2199	diguanylate cyclase activity
AOT11_18930	COG2719	SpoVR family
AOT11_18935	COG2718	Belongs to the UPF0229 family
AOT11_18940	COG2766	serine protein kinase
AOT11_18955	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AOT11_18970	COG1882	Formate acetyltransferase
AOT11_18995	COG4215	(ABC) transporter
AOT11_19010	COG0708	Exodeoxyribonuclease III
AOT11_19015	COG0840	transmembrane signaling receptor activity
AOT11_19025	COG3923	Primosomal replication protein n
AOT11_19035	COG1199	ATP-dependent helicase activity
AOT11_19040	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AOT11_19060	COG1278	Cold shock
AOT11_19070	COG0542	response to heat
AOT11_19075	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AOT11_19080	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AOT11_19095	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AOT11_19105	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AOT11_19115	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AOT11_19140	COG3070	regulator of competence-specific genes
AOT11_19155	COG0745	RESPONSE REGULATOR receiver
AOT11_19160	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AOT11_19165	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOT11_19170	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
AOT11_19180	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AOT11_19195	COG4067	protein conserved in archaea
AOT11_19195	COG0189	ligase activity
AOT11_19205	COG4106	trans-aconitate 2-methyltransferase activity
AOT11_19230	COG2255	four-way junction helicase activity
AOT11_19235	COG1271	oxidase subunit
AOT11_19240	COG1294	oxidase, subunit
AOT11_19250	COG0824	Thioesterase
AOT11_19255	COG0811	peptide transport
AOT11_19270	COG0823	Involved in the tonB-independent uptake of proteins
AOT11_19275	COG2885	chlorophyll binding
AOT11_19280	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AOT11_19285	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AOT11_19295	COG3766	membrane
AOT11_19305	COG0754	glutathionylspermidine amidase activity
AOT11_19315	COG2205	protein histidine kinase activity
AOT11_19315	COG0784	Response regulator, receiver
AOT11_19420	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AOT11_19435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOT11_19440	COG0840	transmembrane signaling receptor activity
AOT11_19445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AOT11_19450	COG0861	Integral membrane protein TerC family
AOT11_19470	COG2207	Transcriptional regulator
AOT11_19490	COG1032	radical SAM domain protein
AOT11_19515	COG0583	DNA-binding transcription factor activity
AOT11_19525	COG0857	belongs to the CobB CobQ family
AOT11_19525	COG0280	phosphate acetyltransferase
AOT11_19535	COG3092	negative regulation of chromosome organization
AOT11_19545	COG4120	Belongs to the binding-protein-dependent transport system permease family
AOT11_19555	COG0366	Alpha amylase catalytic
AOT11_19560	COG0745	RESPONSE REGULATOR receiver
AOT11_19560	COG3706	GGDEF domain
AOT11_19570	COG0653	protein targeting
AOT11_19580	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AOT11_19615	COG2989	Protein conserved in bacteria
AOT11_19620	COG3108	Peptidase M15
AOT11_19625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOT11_19640	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AOT11_19665	COG1846	Transcriptional regulator
AOT11_19670	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOT11_19695	COG1448	Aminotransferase
AOT11_19700	COG3437	response regulator, receiver
AOT11_19700	COG2770	Histidine kinase
AOT11_19720	COG0840	transmembrane signaling receptor activity
AOT11_19725	COG0720	synthase
AOT11_19740	COG2200	EAL domain
AOT11_19745	COG1760	l-serine dehydratase
AOT11_19750	COG0814	amino acid
AOT11_19755	COG0494	nUDIX hydrolase
AOT11_19770	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AOT11_19785	COG3106	COG3106 Predicted ATPase
AOT11_19790	COG3768	UPF0283 membrane protein
AOT11_19795	COG3283	Transcriptional regulator of aromatic amino acids metabolism
AOT11_19800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOT11_19815	COG0471	metal ion transport
AOT11_19820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOT11_19820	COG4191	Histidine kinase
AOT11_19830	COG3706	GGDEF domain
AOT11_19835	COG2199	diguanylate cyclase activity
AOT11_19835	COG2200	EAL domain
AOT11_19850	COG5001	Diguanylate cyclase
AOT11_19850	COG3300	MHYT domain
AOT11_19855	COG1328	CTP reductase activity
AOT11_19860	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AOT11_19865	COG0583	DNA-binding transcription factor activity
AOT11_19880	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AOT11_19885	COG4667	esterase of the alpha-beta hydrolase superfamily
AOT11_19895	COG1597	lipid kinase activity
AOT11_19900	COG0814	amino acid
AOT11_19915	COG0783	Belongs to the Dps family
AOT11_19930	COG1132	(ABC) transporter
AOT11_19935	COG1132	(ABC) transporter
AOT11_19940	COG1115	amino acid carrier protein
AOT11_19955	COG1596	polysaccharide export
AOT11_19985	COG0297	glycogen (starch) synthase activity
AOT11_19985	COG0438	transferase activity, transferring glycosyl groups
AOT11_20040	COG0443	Heat shock 70 kDa protein
AOT11_20045	COG0443	Heat shock 70 kDa protein
AOT11_20055	COG3706	GGDEF domain
AOT11_20075	COG3713	MltA-interacting MipA family protein
AOT11_20105	COG4964	Belongs to the GSP D family
AOT11_20115	COG2894	cell division
AOT11_20155	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AOT11_20165	COG1643	Atp-dependent helicase
AOT11_20190	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AOT11_20195	COG5380	lipid catabolic process
AOT11_20200	COG2814	Major facilitator Superfamily
AOT11_20205	COG0010	Belongs to the arginase family
AOT11_20270	COG3706	GGDEF domain
AOT11_20270	COG0745	RESPONSE REGULATOR receiver
AOT11_20320	COG0295	cytidine deaminase activity
AOT11_20335	COG2885	chlorophyll binding
AOT11_20350	COG0277	FAD linked oxidase domain protein
AOT11_20350	COG0247	lactate metabolic process
AOT11_20355	COG2020	methyltransferase activity
AOT11_20360	COG5640	endopeptidase activity
AOT11_20375	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AOT11_20385	COG1228	amidohydrolase
AOT11_20395	COG4326	sporulation control protein
AOT11_20470	COG0653	protein targeting
AOT11_20485	COG4628	conserved protein (DUF2132)
AOT11_20640	COG1942	4-Oxalocrotonate Tautomerase
AOT11_20650	COG0384	phenazine biosynthesis protein PhzF
AOT11_20855	COG0456	acetyltransferase
AOT11_20855	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AOT11_20935	COG2161	toxin-antitoxin pair type II binding
AOT11_20940	COG4115	mRNA cleavage
AOT11_20990	COG1942	4-Oxalocrotonate Tautomerase
AOT11_21065	COG4628	conserved protein (DUF2132)
AOT11_21185	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AOT11_21295	COG0346	lactoylglutathione lyase activity
AOT11_21300	COG2026	Addiction module toxin, RelE StbE family
AOT11_21350	COG0534	Mate efflux family protein
AOT11_21355	COG0307	riboflavin synthase, alpha
AOT11_21375	COG3706	GGDEF domain
AOT11_21385	COG0791	NLP P60 protein
AOT11_21390	COG0840	transmembrane signaling receptor activity
AOT11_21420	COG0746	molybdenum cofactor guanylyltransferase activity
AOT11_21425	COG3842	ATPase activity
AOT11_21430	COG4662	Binding-protein-dependent transport system inner membrane component
AOT11_21440	COG2204	response regulator
AOT11_21445	COG3852	Histidine kinase
AOT11_21460	COG0488	(ABC) transporter
AOT11_21470	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AOT11_21500	COG3383	formate dehydrogenase (NAD+) activity
AOT11_21500	COG0243	molybdopterin cofactor binding
AOT11_21505	COG0437	4 iron, 4 sulfur cluster binding
AOT11_21535	COG0004	ammonium transporteR
AOT11_21540	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AOT11_21545	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AOT11_21550	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AOT11_21555	COG1177	transmembrane transport
AOT11_21560	COG1176	ABC-type spermidine putrescine transport system, permease component I
AOT11_21570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOT11_21585	COG2217	Heavy metal translocating P-type atpase
AOT11_21595	COG2010	Cytochrome c
AOT11_21610	COG3278	Belongs to the heme-copper respiratory oxidase family
AOT11_21645	COG3120	sequence-specific DNA binding
AOT11_21650	COG1067	ATP-dependent peptidase activity
AOT11_21670	COG0488	(ABC) transporter
AOT11_21680	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AOT11_21680	COG0116	Belongs to the methyltransferase superfamily
AOT11_21695	COG2902	Dehydrogenase
AOT11_21700	COG0308	aminopeptidase N
AOT11_21720	COG1956	GAF domain-containing protein
AOT11_21725	COG1132	(ABC) transporter
AOT11_21730	COG2995	paraquat-inducible protein a
AOT11_21735	COG3008	intermembrane lipid transfer
AOT11_21745	COG2996	Protein conserved in bacteria
AOT11_21760	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AOT11_21770	COG3706	GGDEF domain
AOT11_21775	COG1793	dna ligase
AOT11_21780	COG1366	Belongs to the anti-sigma-factor antagonist family
AOT11_21810	COG2204	response regulator
AOT11_21855	COG0438	transferase activity, transferring glycosyl groups
AOT11_21865	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AOT11_21895	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AOT11_21900	COG0363	glucosamine-6-phosphate deaminase activity
AOT11_21905	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AOT11_21910	COG4565	transcriptional regulatory protein
AOT11_21915	COG3290	protein histidine kinase activity
AOT11_21930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOT11_21955	COG1115	amino acid carrier protein
AOT11_21970	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AOT11_21975	COG0204	Acyl-transferase
AOT11_21980	COG0348	domain, Protein
AOT11_21985	COG0437	4 iron, 4 sulfur cluster binding
AOT11_21995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOT11_22000	COG4597	amino acid ABC transporter
AOT11_22005	COG0765	amino acid transport
AOT11_22010	COG1126	abc transporter atp-binding protein
AOT11_22015	COG0670	Belongs to the BI1 family
AOT11_22020	COG2920	part of a sulfur-relay system
AOT11_22035	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA