locus-tag	class	description
BKP57_00005	COG3599	regulation of cell shape
BKP57_00030	COG3331	DNA recombination
BKP57_00035	COG4499	WXG100 protein secretion system (Wss), protein YukC
BKP57_00035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKP57_00040	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BKP57_00045	COG3935	DnaD domain protein
BKP57_00050	COG0017	Asparaginyl-tRNA synthetase
BKP57_00055	COG0436	Aminotransferase
BKP57_00070	COG1199	ATP-dependent helicase activity
BKP57_00070	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BKP57_00075	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BKP57_00075	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BKP57_00080	COG0617	tRNA 3'-terminal CCA addition
BKP57_00085	COG0438	transferase activity, transferring glycosyl groups
BKP57_00090	COG1803	Methylglyoxal synthase
BKP57_00095	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BKP57_00100	COG1694	Mazg nucleotide pyrophosphohydrolase
BKP57_00105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BKP57_00110	COG2738	Putative neutral zinc metallopeptidase
BKP57_00120	COG4347	Protein of unknown function (DUF1405)
BKP57_00130	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BKP57_00135	COG0723	plastoquinol--plastocyanin reductase activity
BKP57_00145	COG5582	Belongs to the UPF0302 family
BKP57_00155	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BKP57_00160	COG0287	Prephenate dehydrogenase
BKP57_00165	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BKP57_00170	COG4401	Chorismate mutase type I
BKP57_00175	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BKP57_00180	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BKP57_00185	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BKP57_00190	COG0105	UTP biosynthetic process
BKP57_00195	COG0142	geranyltranstransferase activity
BKP57_00200	COG2226	methyltransferase
BKP57_00205	COG0142	geranyltranstransferase activity
BKP57_00215	COG0776	regulation of translation
BKP57_00220	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BKP57_00240	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BKP57_00245	COG1160	GTP binding
BKP57_00260	COG0539	negative regulation of cytoplasmic translation
BKP57_00270	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BKP57_00280	COG2959	enzyme of heme biosynthesis
BKP57_00285	COG3409	Peptidoglycan-binding domain 1 protein
BKP57_00285	COG3773	Cell wall hydrolase
BKP57_00290	COG2339	peptidase activity
BKP57_00300	COG0492	ferredoxin-NADP+ reductase activity
BKP57_00305	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BKP57_00310	COG4862	establishment of competence for transformation
BKP57_00325	COG0514	ATP-dependent DNA helicase (RecQ)
BKP57_00350	COG5002	protein histidine kinase activity
BKP57_00355	COG0745	RESPONSE REGULATOR receiver
BKP57_00360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BKP57_00365	COG1333	cytochrome c biogenesis protein
BKP57_00370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP57_00375	COG1187	pseudouridine synthase activity
BKP57_00380	COG0700	Nucleoside recognition
BKP57_00385	COG2715	membrane protein required for spore maturation
BKP57_00390	COG1686	Belongs to the peptidase S11 family
BKP57_00395	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BKP57_00400	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BKP57_00405	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BKP57_00425	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BKP57_00435	COG0697	spore germination
BKP57_00455	COG2172	sigma factor antagonist activity
BKP57_00465	COG1686	Belongs to the peptidase S11 family
BKP57_00480	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BKP57_00485	COG4974	Belongs to the 'phage' integrase family
BKP57_00495	COG0735	belongs to the Fur family
BKP57_00500	COG1300	Membrane
BKP57_00505	COG1379	DNA repair
BKP57_00515	COG0667	Aldo Keto reductase
BKP57_00525	COG0300	oxidoreductase activity
BKP57_00530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKP57_00535	COG0584	glycerophosphoryl diester phosphodiesterase
BKP57_00540	COG1234	tRNA 3'-trailer cleavage
BKP57_00545	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_00555	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BKP57_00560	COG2195	Cleaves the N-terminal amino acid of tripeptides
BKP57_00565	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKP57_00570	COG0346	lactoylglutathione lyase activity
BKP57_00575	COG4129	membrane
BKP57_00585	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKP57_00590	COG0022	dehydrogenase e1 component
BKP57_00595	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BKP57_00600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BKP57_00605	COG3426	butyrate kinase activity
BKP57_00615	COG0280	phosphate acetyltransferase
BKP57_00620	COG3290	protein histidine kinase activity
BKP57_00620	COG3829	transcription factor binding
BKP57_00630	COG0527	aspartate kinase activity
BKP57_00635	COG0745	RESPONSE REGULATOR receiver
BKP57_00640	COG0750	zinc metalloprotease
BKP57_00645	COG0497	DNA recombination
BKP57_00650	COG1438	arginine binding
BKP57_00655	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BKP57_00665	COG0142	geranyltranstransferase activity
BKP57_00670	COG1722	exodeoxyribonuclease VII activity
BKP57_00675	COG1570	exodeoxyribonuclease VII activity
BKP57_00680	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BKP57_00685	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BKP57_00690	COG1302	Protein conserved in bacteria
BKP57_00695	COG0439	Biotin carboxylase
BKP57_00700	COG0511	ligase activity, forming carbon-carbon bonds
BKP57_00740	COG3854	ATPases associated with a variety of cellular activities
BKP57_00745	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BKP57_00750	COG0006	proline dipeptidase activity
BKP57_00765	COG1752	Esterase of the alpha-beta hydrolase superfamily
BKP57_00770	COG1321	iron dependent repressor
BKP57_00775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKP57_00780	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKP57_00785	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BKP57_00790	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BKP57_00795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BKP57_00810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BKP57_00850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKP57_00860	COG1368	sulfuric ester hydrolase activity
BKP57_00865	COG1940	carbohydrate kinase activity
BKP57_00875	COG0697	spore germination
BKP57_00885	COG0457	Tetratricopeptide repeat
BKP57_00885	COG0705	Rhomboid family
BKP57_00895	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BKP57_00900	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BKP57_00915	COG0704	Plays a role in the regulation of phosphate uptake
BKP57_00925	COG0477	Major facilitator Superfamily
BKP57_00930	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BKP57_00965	COG0704	Plays a role in the regulation of phosphate uptake
BKP57_00970	COG1030	water channel activity
BKP57_00995	COG0513	Belongs to the DEAD box helicase family
BKP57_01000	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BKP57_01005	COG2384	SAM-dependent methyltransferase
BKP57_01020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BKP57_01025	COG0358	DNA primase activity
BKP57_01030	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BKP57_01035	COG0517	IMP dehydrogenase activity
BKP57_01040	COG0751	glycine-tRNA ligase activity
BKP57_01045	COG0752	glycyl-tRNA synthetase alpha subunit
BKP57_01050	COG1381	Involved in DNA repair and RecF pathway recombination
BKP57_01055	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BKP57_01060	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BKP57_01065	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BKP57_01070	COG1480	7TM receptor with intracellular HD hydrolase
BKP57_01075	COG1702	phosphate starvation-inducible protein PhoH
BKP57_01095	COG4864	UPF0365 protein
BKP57_01100	COG1030	water channel activity
BKP57_01105	COG1610	YqeY-like protein
BKP57_01110	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BKP57_01115	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BKP57_01120	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKP57_01125	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BKP57_01130	COG2264	protein methyltransferase activity
BKP57_01135	COG0484	heat shock protein binding
BKP57_01140	COG0443	Heat shock 70 kDa protein
BKP57_01145	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BKP57_01150	COG1420	regulation of RNA biosynthetic process
BKP57_01155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BKP57_01160	COG0481	GTPase activity
BKP57_01170	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKP57_01175	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BKP57_01180	COG0268	Binds directly to 16S ribosomal RNA
BKP57_01185	COG1466	dna polymerase III delta subunit
BKP57_01190	COG2333	competence protein COMEC
BKP57_01190	COG0658	competence protein
BKP57_01195	COG2131	deaminase
BKP57_01205	COG2226	methyltransferase
BKP57_01210	COG0799	negative regulation of ribosome biogenesis
BKP57_01215	COG1713	HD superfamily hydrolase involved in NAD metabolism
BKP57_01220	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BKP57_01225	COG1534	Rna-binding protein
BKP57_01230	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BKP57_01235	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BKP57_01240	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BKP57_01250	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BKP57_01250	COG2111	Na H antiporter
BKP57_01255	COG1006	Multisubunit Na H antiporter MnhC subunit
BKP57_01260	COG0651	ATP synthesis coupled electron transport
BKP57_01270	COG2212	antiporter activity
BKP57_01285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_01285	COG1263	PTS System
BKP57_01290	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BKP57_01295	COG1191	sigma factor activity
BKP57_01320	COG5632	N-Acetylmuramoyl-L-alanine amidase
BKP57_01340	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BKP57_01350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BKP57_01355	COG0572	uridine kinase
BKP57_01365	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BKP57_01370	COG3906	Belongs to the UPF0473 family
BKP57_01375	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BKP57_01380	COG4472	Bacterial protein of unknown function (DUF965)
BKP57_01385	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BKP57_01390	COG0628	permease
BKP57_01400	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BKP57_01410	COG0482	sulfurtransferase activity
BKP57_01415	COG1104	cysteine desulfurase activity
BKP57_01420	COG1959	2 iron, 2 sulfur cluster binding
BKP57_01425	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BKP57_01440	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BKP57_01445	COG0124	histidyl-tRNA synthetase
BKP57_01455	COG1490	D-aminoacyl-tRNA deacylase activity
BKP57_01460	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BKP57_01465	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BKP57_01470	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BKP57_01470	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BKP57_01480	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKP57_01480	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BKP57_01490	COG2244	polysaccharide biosynthetic process
BKP57_01495	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BKP57_01505	COG1862	Preprotein translocase
BKP57_01510	COG0343	queuine tRNA-ribosyltransferase activity
BKP57_01515	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BKP57_01525	COG2255	four-way junction helicase activity
BKP57_01530	COG0632	four-way junction helicase activity
BKP57_01535	COG0217	transcriptional regulatory protein
BKP57_01545	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BKP57_01550	COG3344	reverse transcriptase
BKP57_01560	COG0077	Prephenate dehydratase
BKP57_01565	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BKP57_01575	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BKP57_01580	COG2868	ribosomal protein
BKP57_01585	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BKP57_01590	COG1994	Peptidase M50
BKP57_01600	COG2894	cell division
BKP57_01605	COG0850	regulation of cytokinetic process
BKP57_01615	COG1792	Involved in formation and maintenance of cell shape
BKP57_01620	COG1077	Cell shape determining protein MreB Mrl
BKP57_01630	COG2003	Belongs to the UPF0758 family
BKP57_01640	COG0285	dihydrofolate synthase activity
BKP57_01645	COG4067	protein conserved in archaea
BKP57_01645	COG0189	ligase activity
BKP57_01655	COG0525	valine-tRNA ligase activity
BKP57_01670	COG1388	LysM domain
BKP57_01670	COG1388	LysM domain
BKP57_01680	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BKP57_01685	COG0113	porphobilinogen synthase activity
BKP57_01695	COG0181	hydroxymethylbilane synthase activity
BKP57_01700	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BKP57_01705	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BKP57_01715	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BKP57_01725	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BKP57_01730	COG0544	peptidyl-prolyl cis-trans isomerase activity
BKP57_01745	COG0431	NADPH-dependent FMN reductase
BKP57_01745	COG3976	FMN-binding domain protein
BKP57_01745	COG1053	succinate dehydrogenase
BKP57_01750	COG1053	succinate dehydrogenase
BKP57_01750	COG0431	NADPH-dependent FMN reductase
BKP57_01750	COG3976	FMN-binding domain protein
BKP57_01765	COG0154	amidase activity
BKP57_01770	COG0840	transmembrane signaling receptor activity
BKP57_01800	COG5298	Protein conserved in bacteria
BKP57_01805	COG0622	Phosphoesterase
BKP57_01810	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BKP57_01815	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BKP57_01820	COG5401	PFAM Sporulation and spore germination
BKP57_01825	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BKP57_01830	COG1846	Transcriptional regulator
BKP57_01850	COG0783	Belongs to the Dps family
BKP57_01855	COG0314	molybdopterin synthase activity
BKP57_01860	COG1763	Mo-molybdopterin cofactor biosynthetic process
BKP57_01870	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BKP57_01880	COG1664	Polymer-forming cytoskeletal
BKP57_01885	COG1846	Transcriptional regulator
BKP57_01900	COG1525	nuclease
BKP57_01910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKP57_01925	COG2211	Major facilitator Superfamily
BKP57_01950	COG1725	Transcriptional regulator
BKP57_01975	COG1733	regulation of RNA biosynthetic process
BKP57_01990	COG2085	NADP oxidoreductase coenzyme F420-dependent
BKP57_02010	COG1131	(ABC) transporter
BKP57_02030	COG4584	PFAM Integrase catalytic
BKP57_02030	COG2390	Transcriptional regulator
BKP57_02035	COG1484	DNA-dependent DNA replication
BKP57_02100	COG1404	Belongs to the peptidase S8 family
BKP57_02205	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BKP57_02205	COG0551	DNA topoisomerase type I activity
BKP57_02240	COG2197	response regulator
BKP57_02245	COG0824	Thioesterase
BKP57_02250	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BKP57_02255	COG1053	succinate dehydrogenase
BKP57_02260	COG2009	succinate dehydrogenase
BKP57_02265	COG1719	4-vinyl reductase, 4VR
BKP57_02270	COG0322	excinuclease ABC activity
BKP57_02275	COG3118	belongs to the thioredoxin family
BKP57_02280	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BKP57_02285	COG2086	electron transfer activity
BKP57_02290	COG1024	Enoyl-CoA hydratase
BKP57_02295	COG1309	transcriptional regulator
BKP57_02300	COG0318	PFAM AMP-dependent synthetase and ligase
BKP57_02305	COG3766	membrane
BKP57_02310	COG1193	negative regulation of DNA recombination
BKP57_02315	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BKP57_02315	COG1796	DNA polymerase
BKP57_02320	COG1286	toxin biosynthetic process
BKP57_02325	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BKP57_02330	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BKP57_02335	COG0072	phenylalanine-tRNA ligase activity
BKP57_02335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKP57_02340	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BKP57_02345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKP57_02370	COG4555	ABC transporter
BKP57_02375	COG0741	lytic transglycosylase activity
BKP57_02380	COG1363	Peptidase, m42
BKP57_02385	COG0756	dUTP diphosphatase activity
BKP57_02395	COG0398	Pfam SNARE associated Golgi protein
BKP57_02405	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BKP57_02410	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BKP57_02415	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BKP57_02430	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BKP57_02440	COG1484	DNA-dependent DNA replication
BKP57_02445	COG3611	Membrane attachment protein
BKP57_02450	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BKP57_02460	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BKP57_02465	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BKP57_02475	COG0237	dephospho-CoA kinase activity
BKP57_02480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BKP57_02485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BKP57_02485	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BKP57_02490	COG5002	protein histidine kinase activity
BKP57_02495	COG0745	RESPONSE REGULATOR receiver
BKP57_02505	COG0039	L-malate dehydrogenase activity
BKP57_02510	COG0538	isocitrate dehydrogenase activity
BKP57_02515	COG0372	Belongs to the citrate synthase family
BKP57_02520	COG0628	permease
BKP57_02525	COG3030	protein affecting phage T7 exclusion by the F plasmid
BKP57_02535	COG0205	6-phosphofructokinase activity
BKP57_02540	COG0825	malonyl-CoA metabolic process
BKP57_02545	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BKP57_02550	COG1725	Transcriptional regulator
BKP57_02555	COG0281	malic enzyme
BKP57_02560	COG0587	DNA-directed DNA polymerase activity
BKP57_02585	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BKP57_02595	COG4109	DRTGG domain
BKP57_02605	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BKP57_02610	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BKP57_02615	COG0006	proline dipeptidase activity
BKP57_02620	COG0686	Belongs to the AlaDH PNT family
BKP57_02625	COG0589	response to stress
BKP57_02630	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BKP57_02635	COG0827	DNA restriction-modification system
BKP57_02640	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BKP57_02645	COG3874	Sporulation protein YtfJ
BKP57_02655	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BKP57_02665	COG0301	tRNA thio-modification
BKP57_02670	COG1104	cysteine desulfurase activity
BKP57_02675	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BKP57_02680	COG1309	transcriptional regulator
BKP57_02685	COG1956	GAF domain-containing protein
BKP57_02690	COG2199	diguanylate cyclase activity
BKP57_02690	COG2203	Gaf domain
BKP57_02695	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BKP57_02700	COG5444	nuclease activity
BKP57_02710	COG3344	reverse transcriptase
BKP57_02715	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKP57_02720	COG0454	-acetyltransferase
BKP57_02725	COG0517	IMP dehydrogenase activity
BKP57_02730	COG0123	including yeast histone deacetylase and acetoin utilization protein
BKP57_02750	COG1605	Chorismate mutase
BKP57_02750	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BKP57_02770	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BKP57_02780	COG1674	ftsk spoiiie
BKP57_02785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKP57_02790	COG4848	Belongs to the UPF0354 family
BKP57_02795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP57_02805	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BKP57_02810	COG1363	Peptidase, m42
BKP57_02820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKP57_02825	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BKP57_02835	COG0510	thiamine kinase activity
BKP57_02850	COG1187	pseudouridine synthase activity
BKP57_02855	COG2244	polysaccharide biosynthetic process
BKP57_02860	COG2081	HI0933 family
BKP57_02870	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BKP57_02890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKP57_02900	COG0495	leucyl-tRNA aminoacylation
BKP57_02905	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BKP57_02910	COG1454	alcohol dehydrogenase
BKP57_02910	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_02920	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BKP57_02925	COG4990	cell redox homeostasis
BKP57_02930	COG0367	asparagine synthase
BKP57_02935	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BKP57_02940	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BKP57_02945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKP57_02950	COG1116	anion transmembrane transporter activity
BKP57_02955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKP57_02960	COG0494	nUDIX hydrolase
BKP57_03000	COG1505	serine-type exopeptidase activity
BKP57_03010	COG0318	PFAM AMP-dependent synthetase and ligase
BKP57_03015	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BKP57_03020	COG0596	Alpha beta hydrolase
BKP57_03025	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BKP57_03030	COG1169	isochorismate synthase
BKP57_03035	COG1575	Belongs to the MenA family. Type 1 subfamily
BKP57_03040	COG2050	protein possibly involved in aromatic compounds catabolism
BKP57_03045	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BKP57_03050	COG3191	aminopeptidase activity
BKP57_03060	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BKP57_03065	COG4412	M6 family metalloprotease domain protein
BKP57_03065	COG1404	Belongs to the peptidase S8 family
BKP57_03080	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BKP57_03090	COG1098	S1 RNA binding domain
BKP57_03095	COG2155	Conserved Protein
BKP57_03100	COG0166	Belongs to the GPI family
BKP57_03110	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BKP57_03115	COG2032	superoxide dismutase activity
BKP57_03130	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_03135	COG0813	purine-nucleoside phosphorylase activity
BKP57_03145	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BKP57_03150	COG3584	3D domain protein
BKP57_03160	COG1252	NADH dehydrogenase
BKP57_03165	COG0492	ferredoxin-NADP+ reductase activity
BKP57_03170	COG0316	Belongs to the HesB IscA family
BKP57_03175	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BKP57_03180	COG4837	Protein of unknown function (DUF1462)
BKP57_03185	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BKP57_03190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKP57_03195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BKP57_03200	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BKP57_03205	COG0647	UMP catabolic process
BKP57_03210	COG2445	Protein of unknown function DUF86
BKP57_03225	COG4470	Protein conserved in bacteria
BKP57_03235	COG0739	heme binding
BKP57_03240	COG0733	neurotransmitter:sodium symporter activity
BKP57_03250	COG1757	Na H antiporter
BKP57_03260	COG0737	Belongs to the 5'-nucleotidase family
BKP57_03265	COG0730	response to heat
BKP57_03305	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_03310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKP57_03315	COG1757	Na H antiporter
BKP57_03325	COG3938	Belongs to the proline racemase family
BKP57_03330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKP57_03355	COG0006	proline dipeptidase activity
BKP57_03380	COG3279	Response regulator of the LytR AlgR family
BKP57_03385	COG0745	RESPONSE REGULATOR receiver
BKP57_03385	COG2972	Histidine kinase
BKP57_03430	COG0745	RESPONSE REGULATOR receiver
BKP57_03435	COG3290	protein histidine kinase activity
BKP57_03440	COG4565	transcriptional regulatory protein
BKP57_03445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKP57_03455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKP57_03465	COG1132	(ABC) transporter
BKP57_03470	COG1132	(ABC) transporter
BKP57_03475	COG2382	esterase
BKP57_03480	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BKP57_03485	COG2153	protein acetylation
BKP57_03490	COG2323	membrane
BKP57_03520	COG2239	Acts as a magnesium transporter
BKP57_03525	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BKP57_03530	COG0564	pseudouridine synthase activity
BKP57_03535	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BKP57_03540	COG2357	RelA SpoT domain protein
BKP57_03545	COG4116	CYTH
BKP57_03550	COG2346	COG2346, Truncated hemoglobins
BKP57_03565	COG1164	Oligoendopeptidase f
BKP57_03570	COG4469	Competence protein
BKP57_03575	COG4862	establishment of competence for transformation
BKP57_03580	COG1393	Belongs to the ArsC family
BKP57_03595	COG0456	acetyltransferase
BKP57_03610	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BKP57_03615	COG0180	Tryptophanyl-tRNA synthetase
BKP57_03630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BKP57_03635	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKP57_03640	COG1744	ABC transporter substrate-binding protein PnrA-like
BKP57_03665	COG2151	metal-sulfur cluster biosynthetic enzyme
BKP57_03670	COG1073	alpha beta
BKP57_03675	COG0561	phosphatase activity
BKP57_03695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BKP57_03700	COG1307	EDD domain protein, DegV family
BKP57_03715	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BKP57_03720	COG2311	Membrane
BKP57_03755	COG1074	ATP-dependent DNA helicase activity
BKP57_03760	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BKP57_03770	COG0398	Pfam SNARE associated Golgi protein
BKP57_03785	COG0318	PFAM AMP-dependent synthetase and ligase
BKP57_03790	COG0095	Lipoate-protein ligase
BKP57_03800	COG1164	Oligoendopeptidase f
BKP57_03815	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BKP57_03820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKP57_03830	COG3118	belongs to the thioredoxin family
BKP57_03830	COG0492	ferredoxin-NADP+ reductase activity
BKP57_03835	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BKP57_03840	COG2197	response regulator
BKP57_03845	COG4585	Histidine kinase
BKP57_03855	COG2814	Major facilitator Superfamily
BKP57_03870	COG1473	amidohydrolase
BKP57_03875	COG4473	ABC transporter
BKP57_03880	COG1131	(ABC) transporter
BKP57_03885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKP57_03895	COG3069	C4-dicarboxylate transmembrane transporter activity
BKP57_03905	COG0537	adenosine 5'-monophosphoramidase activity
BKP57_03940	COG1510	regulation of RNA biosynthetic process
BKP57_03960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKP57_03970	COG3481	metal-dependent phosphohydrolase, HD sub domain
BKP57_03980	COG1510	regulation of RNA biosynthetic process
BKP57_03985	COG4717	serine-type aminopeptidase activity
BKP57_03990	COG0420	3'-5' exonuclease activity
BKP57_03995	COG1668	transmembrane transport
BKP57_04000	COG4152	abc transporter atp-binding protein
BKP57_04045	COG1024	Enoyl-CoA hydratase
BKP57_04050	COG3679	Belongs to the UPF0342 family
BKP57_04055	COG2508	Transcriptional regulator
BKP57_04060	COG3842	ATPase activity
BKP57_04070	COG0114	fumarate hydratase activity
BKP57_04080	COG2270	Major facilitator Superfamily
BKP57_04090	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BKP57_04100	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BKP57_04110	COG0024	Methionine aminopeptidase
BKP57_04120	COG1028	Short-chain dehydrogenase reductase Sdr
BKP57_04125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BKP57_04145	COG1191	sigma factor activity
BKP57_04150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKP57_04155	COG1132	(ABC) transporter
BKP57_04160	COG1132	(ABC) transporter
BKP57_04180	COG1846	Transcriptional regulator
BKP57_04185	COG1033	growth of symbiont in host cell
BKP57_04185	COG2409	Drug exporters of the RND superfamily
BKP57_04190	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BKP57_04195	COG0534	Mate efflux family protein
BKP57_04200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BKP57_04205	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKP57_04210	COG0567	Dehydrogenase, E1 component
BKP57_04240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BKP57_04250	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKP57_04255	COG3275	phosphorelay sensor kinase activity
BKP57_04260	COG3279	Response regulator of the LytR AlgR family
BKP57_04265	COG3162	membrane
BKP57_04270	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKP57_04275	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKP57_04280	COG0563	adenylate kinase activity
BKP57_04285	COG0823	Involved in the tonB-independent uptake of proteins
BKP57_04285	COG1506	peptidase
BKP57_04285	COG4946	Tricorn protease homolog
BKP57_04290	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BKP57_04295	COG0505	Belongs to the CarA family
BKP57_04320	COG1131	(ABC) transporter
BKP57_04325	COG2197	response regulator
BKP57_04330	COG4585	Histidine kinase
BKP57_04355	COG2814	Major facilitator Superfamily
BKP57_04360	COG2233	PERMEase
BKP57_04365	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BKP57_04380	COG0506	proline dehydrogenase activity
BKP57_04385	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_04400	COG0366	Alpha amylase catalytic
BKP57_04410	COG2190	(PTS) system
BKP57_04410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_04410	COG1263	PTS System
BKP57_04420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKP57_04435	COG1024	Enoyl-CoA hydratase
BKP57_04440	COG1024	Enoyl-CoA hydratase
BKP57_04445	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_04455	COG1960	acyl-CoA dehydrogenase activity
BKP57_04460	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BKP57_04465	COG3829	transcription factor binding
BKP57_04465	COG3290	protein histidine kinase activity
BKP57_04475	COG2365	Tyrosine phosphatase family
BKP57_04480	COG1473	amidohydrolase
BKP57_04485	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BKP57_04490	COG0583	DNA-binding transcription factor activity
BKP57_04495	COG0318	PFAM AMP-dependent synthetase and ligase
BKP57_04500	COG2070	2-Nitropropane dioxygenase
BKP57_04505	COG2986	histidine ammonia-lyase
BKP57_04520	COG1228	amidohydrolase
BKP57_04525	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BKP57_04530	COG0010	Belongs to the arginase family
BKP57_04535	COG0583	DNA-binding transcription factor activity
BKP57_04550	COG2176	DNA-directed DNA polymerase activity
BKP57_04570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKP57_04590	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BKP57_04595	COG0326	Molecular chaperone. Has ATPase activity
BKP57_04610	COG0277	FAD linked oxidase domain protein
BKP57_04615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKP57_04620	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BKP57_04625	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BKP57_04630	COG2814	Major facilitator Superfamily
BKP57_04655	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BKP57_04685	COG1247	-acetyltransferase
BKP57_04710	COG4474	Belongs to the UPF0398 family
BKP57_04730	COG1970	mechanosensitive ion channel activity
BKP57_04740	COG2318	DinB family
BKP57_04745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKP57_04750	COG1227	inorganic diphosphatase activity
BKP57_04755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKP57_04765	COG2364	Membrane
BKP57_04770	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BKP57_04770	COG0456	acetyltransferase
BKP57_04780	COG1271	oxidase subunit
BKP57_04785	COG1294	oxidase, subunit
BKP57_04790	COG4988	ABC transporter
BKP57_04795	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BKP57_04805	COG1408	metallophosphoesterase
BKP57_04810	COG0726	polysaccharide deacetylase
BKP57_04830	COG0653	protein targeting
BKP57_04835	COG1082	Xylose isomerase domain protein TIM barrel
BKP57_04840	COG0673	inositol 2-dehydrogenase activity
BKP57_04875	COG4584	PFAM Integrase catalytic
BKP57_04875	COG2390	Transcriptional regulator
BKP57_04880	COG1484	DNA-dependent DNA replication
BKP57_04885	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKP57_04900	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BKP57_04910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BKP57_04920	COG0165	Argininosuccinate lyase
BKP57_04930	COG0604	alcohol dehydrogenase
BKP57_04930	COG3321	synthase
BKP57_05090	COG0735	belongs to the Fur family
BKP57_05095	COG2096	Adenosyltransferase
BKP57_05105	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BKP57_05115	COG0745	RESPONSE REGULATOR receiver
BKP57_05120	COG2205	protein histidine kinase activity
BKP57_05125	COG1136	(ABC) transporter
BKP57_05130	COG0577	efflux transmembrane transporter activity
BKP57_05135	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BKP57_05145	COG1132	(ABC) transporter
BKP57_05150	COG3557	Belongs to the UPF0374 family
BKP57_05175	COG1988	membrane-bound metal-dependent
BKP57_05185	COG2137	regulation of response to DNA damage stimulus
BKP57_05190	COG1090	epimerase
BKP57_05205	COG2188	Transcriptional regulator
BKP57_05220	COG1131	(ABC) transporter
BKP57_05225	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BKP57_05235	COG1131	(ABC) transporter
BKP57_05240	COG1725	Transcriptional regulator
BKP57_05260	COG0542	response to heat
BKP57_05265	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKP57_05275	COG2056	Na+-H+ antiporter family
BKP57_05290	COG0477	Major facilitator Superfamily
BKP57_05295	COG0765	amino acid transport
BKP57_05300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKP57_05305	COG2217	Heavy metal translocating P-type atpase
BKP57_05320	COG1295	ribonuclease BN
BKP57_05330	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BKP57_05335	COG1115	amino acid carrier protein
BKP57_05340	COG2066	Belongs to the glutaminase family
BKP57_05350	COG2340	Cysteine-rich secretory protein family
BKP57_05355	COG1077	Cell shape determining protein MreB Mrl
BKP57_05360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BKP57_05365	COG1960	acyl-CoA dehydrogenase activity
BKP57_05370	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_05400	COG1414	Transcriptional regulator
BKP57_05410	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_05415	COG0028	Belongs to the TPP enzyme family
BKP57_05420	COG0436	Aminotransferase
BKP57_05425	COG1757	Na H antiporter
BKP57_05445	COG0733	neurotransmitter:sodium symporter activity
BKP57_05450	COG0446	pyridine nucleotide-disulphide oxidoreductase
BKP57_05475	COG0488	(ABC) transporter
BKP57_05495	COG0307	riboflavin synthase, alpha
BKP57_05500	COG0840	transmembrane signaling receptor activity
BKP57_05505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKP57_05505	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKP57_05510	COG0730	response to heat
BKP57_05515	COG0425	Belongs to the sulfur carrier protein TusA family
BKP57_05520	COG2210	Belongs to the sulfur carrier protein TusA family
BKP57_05525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKP57_05525	COG0425	Belongs to the sulfur carrier protein TusA family
BKP57_05535	COG2210	Belongs to the sulfur carrier protein TusA family
BKP57_05545	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BKP57_05550	COG1937	Protein conserved in bacteria
BKP57_05555	COG0247	lactate metabolic process
BKP57_05560	COG0277	FAD linked oxidase domain protein
BKP57_05565	COG3835	regulator
BKP57_05580	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_05585	COG0166	Belongs to the GPI family
BKP57_05590	COG1619	proteins homologs of microcin C7 resistance protein MccF
BKP57_05605	COG1695	Transcriptional regulator
BKP57_05620	COG1447	Phosphotransferase system cellobiose-specific component IIA
BKP57_05625	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP57_05640	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BKP57_05640	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BKP57_05650	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BKP57_05655	COG2079	MmgE PrpD family protein
BKP57_05660	COG0372	Belongs to the citrate synthase family
BKP57_05665	COG0583	DNA-binding transcription factor activity
BKP57_05675	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BKP57_05680	COG2814	Major facilitator Superfamily
BKP57_05695	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BKP57_05700	COG0583	DNA-binding transcription factor activity
BKP57_05710	COG3546	catalase activity
BKP57_05715	COG0626	cystathionine gamma-synthase activity
BKP57_05725	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BKP57_05730	COG1694	Mazg nucleotide pyrophosphohydrolase
BKP57_05755	COG1695	Transcriptional regulator
BKP57_05770	COG4496	protein, YerC YecD
BKP57_05780	COG0351	phosphomethylpyrimidine kinase
BKP57_05790	COG0531	amino acid
BKP57_05795	COG0702	epimerase
BKP57_05810	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BKP57_05825	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP57_05845	COG3711	transcriptional antiterminator
BKP57_05845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_05850	COG2205	protein histidine kinase activity
BKP57_05855	COG0745	RESPONSE REGULATOR receiver
BKP57_05900	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BKP57_05905	COG1597	lipid kinase activity
BKP57_05910	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BKP57_05915	COG0154	amidase activity
BKP57_05920	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BKP57_05955	COG4851	CamS sex pheromone cAM373 precursor
BKP57_05960	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BKP57_05965	COG0210	DNA helicase
BKP57_05970	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BKP57_05975	COG4496	protein, YerC YecD
BKP57_05980	COG1470	cell adhesion involved in biofilm formation
BKP57_05985	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BKP57_05995	COG0151	Belongs to the GarS family
BKP57_06000	COG0138	bifunctional purine biosynthesis protein purh
BKP57_06005	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BKP57_06010	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BKP57_06015	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BKP57_06020	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BKP57_06025	COG0047	phosphoribosylformylglycinamidine synthase activity
BKP57_06030	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BKP57_06035	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BKP57_06040	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BKP57_06045	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BKP57_06050	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BKP57_06055	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BKP57_06065	COG2258	MOSC domain
BKP57_06070	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKP57_06080	COG0840	transmembrane signaling receptor activity
BKP57_06085	COG2252	PERMEase
BKP57_06095	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BKP57_06100	COG3842	ATPase activity
BKP57_06115	COG2826	transposase and inactivated derivatives, IS30 family
BKP57_06120	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BKP57_06125	COG0527	aspartate kinase activity
BKP57_06130	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKP57_06130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BKP57_06135	COG0662	Cupin 2, conserved barrel domain protein
BKP57_06145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BKP57_06160	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BKP57_06165	COG2207	Transcriptional regulator
BKP57_06180	COG1181	Belongs to the D-alanine--D-alanine ligase family
BKP57_06185	COG2169	Transcriptional regulator
BKP57_06190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BKP57_06200	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BKP57_06235	COG1595	DNA-templated transcription, initiation
BKP57_06250	COG1131	(ABC) transporter
BKP57_06275	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BKP57_06290	COG0640	Transcriptional regulator
BKP57_06300	COG2226	methyltransferase
BKP57_06315	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BKP57_06325	COG0641	radical SAM
BKP57_06330	COG2723	6-phospho-beta-galactosidase activity
BKP57_06340	COG1263	PTS System
BKP57_06340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_06340	COG2190	(PTS) system
BKP57_06345	COG3711	transcriptional antiterminator
BKP57_06370	COG0561	phosphatase activity
BKP57_06375	COG2723	6-phospho-beta-galactosidase activity
BKP57_06380	COG1263	PTS System
BKP57_06380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_06380	COG2190	(PTS) system
BKP57_06385	COG3711	transcriptional antiterminator
BKP57_06390	COG1486	melibiose metabolic process
BKP57_06415	COG0189	ligase activity
BKP57_06435	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKP57_06445	COG0693	protein deglycase activity
BKP57_06450	COG2378	regulation of single-species biofilm formation
BKP57_06455	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BKP57_06485	COG1674	ftsk spoiiie
BKP57_06490	COG2946	Replication initiation factor
BKP57_06520	COG0741	lytic transglycosylase activity
BKP57_06520	COG0791	NLP P60 protein
BKP57_06535	COG0210	DNA helicase
BKP57_06555	COG1131	(ABC) transporter
BKP57_06570	COG0789	Transcriptional regulator
BKP57_06575	COG2814	Major facilitator Superfamily
BKP57_06630	COG0741	lytic transglycosylase activity
BKP57_06630	COG0791	NLP P60 protein
BKP57_06635	COG5644	endopeptidase inhibitor activity
BKP57_06650	COG0433	COG0433 Predicted ATPase
BKP57_06685	COG2946	Replication initiation factor
BKP57_06690	COG1674	ftsk spoiiie
BKP57_06720	COG1396	sequence-specific DNA binding
BKP57_06725	COG2856	Zn peptidase
BKP57_06740	COG0519	Catalyzes the synthesis of GMP from XMP
BKP57_06740	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BKP57_06745	COG1305	Transglutaminase-like
BKP57_06750	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BKP57_06755	COG0714	Associated with various cellular activities
BKP57_06770	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BKP57_06775	COG0154	amidase activity
BKP57_06780	COG0531	amino acid
BKP57_06785	COG0697	spore germination
BKP57_06800	COG0444	Belongs to the ABC transporter superfamily
BKP57_06805	COG4608	Belongs to the ABC transporter superfamily
BKP57_06815	COG0601	transmembrane transport
BKP57_06820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKP57_06825	COG0840	transmembrane signaling receptor activity
BKP57_06840	COG2200	EAL domain
BKP57_06855	COG1510	regulation of RNA biosynthetic process
BKP57_06865	COG1454	alcohol dehydrogenase
BKP57_06870	COG2197	response regulator
BKP57_06875	COG0071	Belongs to the small heat shock protein (HSP20) family
BKP57_06880	COG1442	glycosyl transferase family 8
BKP57_06890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_06890	COG2190	(PTS) system
BKP57_06890	COG1263	PTS System
BKP57_06895	COG2723	6-phospho-beta-galactosidase activity
BKP57_06910	COG1757	Na H antiporter
BKP57_06915	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BKP57_06920	COG1473	amidohydrolase
BKP57_06925	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BKP57_06930	COG1473	amidohydrolase
BKP57_06940	COG1879	ABC-type sugar transport system periplasmic component
BKP57_06945	COG1172	Belongs to the binding-protein-dependent transport system permease family
BKP57_06950	COG1129	ABC transporter
BKP57_06955	COG1869	D-ribose catabolic process
BKP57_06960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKP57_06965	COG1609	Transcriptional regulator
BKP57_06970	COG0747	negative chemotaxis
BKP57_06985	COG0444	Belongs to the ABC transporter superfamily
BKP57_06990	COG4608	Belongs to the ABC transporter superfamily
BKP57_07005	COG1966	Carbon starvation protein
BKP57_07030	COG1115	amino acid carrier protein
BKP57_07050	COG5444	nuclease activity
BKP57_07095	COG0459	protein refolding
BKP57_07100	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BKP57_07105	COG1266	CAAX protease self-immunity
BKP57_07115	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BKP57_07120	COG0488	(ABC) transporter
BKP57_07125	COG0772	Belongs to the SEDS family
BKP57_07130	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BKP57_07135	COG0456	acetyltransferase
BKP57_07140	COG1214	PFAM Peptidase M22, glycoprotease
BKP57_07145	COG0802	atpase or kinase
BKP57_07150	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BKP57_07240	COG3091	SprT-like family
BKP57_07245	COG0753	catalase activity
BKP57_07250	COG2183	response to ionizing radiation
BKP57_07260	COG2208	phosphoserine phosphatase activity
BKP57_07265	COG1191	sigma factor activity
BKP57_07270	COG2172	sigma factor antagonist activity
BKP57_07275	COG1366	Belongs to the anti-sigma-factor antagonist family
BKP57_07280	COG2208	phosphoserine phosphatase activity
BKP57_07285	COG2172	sigma factor antagonist activity
BKP57_07290	COG1366	Belongs to the anti-sigma-factor antagonist family
BKP57_07295	COG1366	Belongs to the anti-sigma-factor antagonist family
BKP57_07305	COG2337	Toxic component of a toxin-antitoxin (TA) module
BKP57_07320	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BKP57_07325	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BKP57_07325	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BKP57_07330	COG0736	holo-[acyl-carrier-protein] synthase activity
BKP57_07335	COG0705	Rhomboid family
BKP57_07340	COG1609	Transcriptional regulator
BKP57_07350	COG0546	phosphoglycolate phosphatase activity
BKP57_07355	COG3428	Bacterial PH domain
BKP57_07360	COG3402	PFAM membrane-flanked domain
BKP57_07365	COG0513	Belongs to the DEAD box helicase family
BKP57_07370	COG0697	spore germination
BKP57_07395	COG1846	Transcriptional regulator
BKP57_07405	COG4152	abc transporter atp-binding protein
BKP57_07410	COG1597	lipid kinase activity
BKP57_07420	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BKP57_07425	COG3639	organic phosphonate transmembrane transporter activity
BKP57_07430	COG3639	organic phosphonate transmembrane transporter activity
BKP57_07435	COG0737	Belongs to the 5'-nucleotidase family
BKP57_07440	COG3212	peptidase
BKP57_07450	COG3850	Histidine kinase
BKP57_07450	COG5002	protein histidine kinase activity
BKP57_07455	COG0745	RESPONSE REGULATOR receiver
BKP57_07470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP57_07480	COG1695	Transcriptional regulator
BKP57_07495	COG1131	(ABC) transporter
BKP57_07500	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BKP57_07520	COG0471	metal ion transport
BKP57_07525	COG5002	protein histidine kinase activity
BKP57_07525	COG3850	Histidine kinase
BKP57_07530	COG0745	RESPONSE REGULATOR receiver
BKP57_07535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKP57_07545	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BKP57_07550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BKP57_07630	COG2084	Dehydrogenase
BKP57_07645	COG2226	methyltransferase
BKP57_07670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_07670	COG1263	PTS System
BKP57_07675	COG1486	melibiose metabolic process
BKP57_07680	COG1737	Transcriptional regulator
BKP57_07700	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_07705	COG2723	6-phospho-beta-galactosidase activity
BKP57_07710	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP57_07710	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP57_07715	COG1447	Phosphotransferase system cellobiose-specific component IIA
BKP57_07725	COG3344	reverse transcriptase
BKP57_07730	COG0363	glucosamine-6-phosphate deaminase activity
BKP57_07755	COG3716	PTS system mannose fructose sorbose family IID component
BKP57_07760	COG3715	PTS system
BKP57_07765	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_07770	COG2222	sugar isomerase
BKP57_07800	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BKP57_07805	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BKP57_07810	COG2017	converts alpha-aldose to the beta-anomer
BKP57_07820	COG0494	nUDIX hydrolase
BKP57_07835	COG1316	TRANSCRIPTIONal
BKP57_07845	COG1316	TRANSCRIPTIONal
BKP57_07850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKP57_07855	COG0438	transferase activity, transferring glycosyl groups
BKP57_07865	COG1216	Glycosyl transferase, family 2
BKP57_07880	COG0584	glycerophosphoryl diester phosphodiesterase
BKP57_07890	COG1682	transport, permease protein
BKP57_07905	COG0438	transferase activity, transferring glycosyl groups
BKP57_07910	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BKP57_07920	COG4193	domain, Protein
BKP57_07925	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BKP57_07930	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BKP57_07935	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BKP57_07940	COG4193	domain, Protein
BKP57_07945	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BKP57_07950	COG2244	polysaccharide biosynthetic process
BKP57_07970	COG2076	Multidrug Resistance protein
BKP57_07990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKP57_08015	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BKP57_08020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKP57_08030	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BKP57_08035	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BKP57_08040	COG0095	Lipoate-protein ligase
BKP57_08045	COG1737	Transcriptional regulator
BKP57_08050	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BKP57_08055	COG1263	PTS System
BKP57_08055	COG2190	(PTS) system
BKP57_08055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_08060	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP57_08065	COG1447	Phosphotransferase system cellobiose-specific component IIA
BKP57_08070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP57_08075	COG1486	melibiose metabolic process
BKP57_08085	COG3394	polysaccharide catabolic process
BKP57_08100	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BKP57_08105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKP57_08145	COG4786	Flagellar basal body rod
BKP57_08150	COG4786	Flagellar basal body rod
BKP57_08155	COG1077	Cell shape determining protein MreB Mrl
BKP57_08160	COG1609	Transcriptional regulator
BKP57_08175	COG2385	sporulation resulting in formation of a cellular spore
BKP57_08180	COG4608	Belongs to the ABC transporter superfamily
BKP57_08185	COG0791	NLP P60 protein
BKP57_08190	COG4166	transmembrane transport
BKP57_08195	COG0444	Belongs to the ABC transporter superfamily
BKP57_08200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKP57_08205	COG0601	transmembrane transport
BKP57_08210	COG2362	D-Aminopeptidase
BKP57_08215	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BKP57_08225	COG4836	Membrane
BKP57_08235	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BKP57_08240	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BKP57_08245	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BKP57_08250	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BKP57_08255	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BKP57_08260	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BKP57_08265	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BKP57_08270	COG0356	it plays a direct role in the translocation of protons across the membrane
BKP57_08280	COG1404	Belongs to the peptidase S8 family
BKP57_08285	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BKP57_08290	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BKP57_08295	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BKP57_08300	COG4475	Protein of unknown function (DUF436)
BKP57_08305	COG0698	ribose 5-phosphate isomerase
BKP57_08310	COG0840	transmembrane signaling receptor activity
BKP57_08315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BKP57_08320	COG1971	Probably functions as a manganese efflux pump
BKP57_08325	COG0009	L-threonylcarbamoyladenylate synthase
BKP57_08345	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BKP57_08350	COG1435	thymidine kinase activity
BKP57_08355	COG0254	rRNA binding
BKP57_08360	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BKP57_08365	COG1494	fructose-1,6-bisphosphatase
BKP57_08370	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BKP57_08375	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BKP57_08380	COG0191	fructose-bisphosphate aldolase activity
BKP57_08385	COG0745	RESPONSE REGULATOR receiver
BKP57_08390	COG0504	CTP synthase activity
BKP57_08395	COG3343	RNA polymerase activity
BKP57_08400	COG1309	transcriptional regulator
BKP57_08405	COG1960	acyl-CoA dehydrogenase activity
BKP57_08410	COG1960	acyl-CoA dehydrogenase activity
BKP57_08415	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKP57_08420	COG0183	Belongs to the thiolase family
BKP57_08425	COG0247	lactate metabolic process
BKP57_08425	COG2181	nitrate reductase activity
BKP57_08430	COG1882	Formate acetyltransferase
BKP57_08435	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BKP57_08440	COG0018	arginyl-trna synthetase
BKP57_08450	COG0039	L-malate dehydrogenase activity
BKP57_08455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BKP57_08470	COG3465	dGTPase activity
BKP57_08475	COG1078	dGTPase activity
BKP57_08480	COG0095	Lipoate-protein ligase
BKP57_08485	COG0280	phosphate acetyltransferase
BKP57_08500	COG3773	Cell wall hydrolase
BKP57_08515	COG2363	Small membrane protein
BKP57_08525	COG1845	cytochrome c oxidase, subunit III
BKP57_08530	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BKP57_08545	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BKP57_08555	COG3594	Acyltransferase
BKP57_08560	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BKP57_08565	COG3285	dna ligase
BKP57_08565	COG1793	dna ligase
BKP57_08570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BKP57_08590	COG0861	Integral membrane protein TerC family
BKP57_08595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BKP57_08600	COG0628	permease
BKP57_08620	COG1114	Component of the transport system for branched-chain amino acids
BKP57_08625	COG0514	ATP-dependent DNA helicase (RecQ)
BKP57_08635	COG1733	regulation of RNA biosynthetic process
BKP57_08640	COG1115	amino acid carrier protein
BKP57_08645	COG1607	acyl-coa hydrolase
BKP57_08650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BKP57_08655	COG1737	Transcriptional regulator
BKP57_08660	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BKP57_08665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_08665	COG1263	PTS System
BKP57_08685	COG0561	phosphatase activity
BKP57_08690	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP57_08700	COG1447	Phosphotransferase system cellobiose-specific component IIA
BKP57_08705	COG2755	lipolytic protein G-D-S-L family
BKP57_08720	COG0488	(ABC) transporter
BKP57_08725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BKP57_08730	COG0156	8-amino-7-oxononanoate synthase activity
BKP57_08735	COG1388	LysM domain
BKP57_08735	COG3584	3D domain protein
BKP57_08745	COG2814	Major facilitator Superfamily
BKP57_08750	COG0534	Mate efflux family protein
BKP57_08760	COG0251	oxidation-reduction process
BKP57_08765	COG0741	lytic transglycosylase activity
BKP57_08825	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BKP57_08835	COG2070	2-Nitropropane dioxygenase
BKP57_08845	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BKP57_08855	COG1136	(ABC) transporter
BKP57_08865	COG2814	Major facilitator Superfamily
BKP57_08880	COG1263	PTS System
BKP57_08880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_08890	COG1737	Transcriptional regulator
BKP57_08895	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BKP57_08900	COG2032	superoxide dismutase activity
BKP57_08935	COG4152	abc transporter atp-binding protein
BKP57_08950	COG0655	NAD(P)H dehydrogenase (quinone) activity
BKP57_08955	COG3103	Sh3 type 3 domain protein
BKP57_08955	COG4991	sh3 domain protein
BKP57_08955	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKP57_08965	COG2226	methyltransferase
BKP57_08970	COG4282	regulation of fungal-type cell wall biogenesis
BKP57_08975	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BKP57_08985	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BKP57_08990	COG2323	membrane
BKP57_08995	COG3383	formate dehydrogenase (NAD+) activity
BKP57_09000	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BKP57_09010	COG3011	Protein conserved in bacteria
BKP57_09015	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BKP57_09025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKP57_09030	COG0655	NAD(P)H dehydrogenase (quinone) activity
BKP57_09035	COG0501	Belongs to the peptidase M48B family
BKP57_09045	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BKP57_09050	COG0427	acetyl-CoA hydrolase
BKP57_09055	COG3279	Response regulator of the LytR AlgR family
BKP57_09065	COG1252	NADH dehydrogenase
BKP57_09075	COG1346	cytolysis
BKP57_09080	COG1380	Effector of murein hydrolase LrgA
BKP57_09085	COG0137	argininosuccinate synthase activity
BKP57_09110	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BKP57_09115	COG0573	inorganic phosphate transmembrane transporter activity
BKP57_09120	COG0581	inorganic phosphate transmembrane transporter activity
BKP57_09125	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BKP57_09155	COG0561	phosphatase activity
BKP57_09160	COG0191	fructose-bisphosphate aldolase activity
BKP57_09165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_09165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_09165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_09170	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_09170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_09170	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_09175	COG1105	Belongs to the carbohydrate kinase PfkB family
BKP57_09185	COG0346	lactoylglutathione lyase activity
BKP57_09190	COG1011	Hydrolase
BKP57_09200	COG0577	efflux transmembrane transporter activity
BKP57_09205	COG1136	(ABC) transporter
BKP57_09210	COG3871	stress protein (general stress protein 26)
BKP57_09230	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BKP57_09255	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BKP57_09260	COG1609	Transcriptional regulator
BKP57_09275	COG1131	(ABC) transporter
BKP57_09280	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BKP57_09285	COG1263	PTS System
BKP57_09285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_09285	COG2190	(PTS) system
BKP57_09290	COG3711	transcriptional antiterminator
BKP57_09295	COG1263	PTS System
BKP57_09295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_09305	COG4821	SIS domain
BKP57_09330	COG1607	acyl-coa hydrolase
BKP57_09335	COG0583	DNA-binding transcription factor activity
BKP57_09350	COG0785	Cytochrome C biogenesis protein
BKP57_09355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP57_09360	COG0745	RESPONSE REGULATOR receiver
BKP57_09365	COG5002	protein histidine kinase activity
BKP57_09380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKP57_09430	COG1028	Short-chain dehydrogenase reductase Sdr
BKP57_09435	COG0583	DNA-binding transcription factor activity
BKP57_09440	COG1937	Protein conserved in bacteria
BKP57_09450	COG3949	Membrane
BKP57_09455	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BKP57_09465	COG2719	SpoVR family
BKP57_09470	COG0803	Belongs to the bacterial solute-binding protein 9 family
BKP57_09475	COG1121	(ABC) transporter
BKP57_09480	COG1321	iron dependent repressor
BKP57_09480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BKP57_09485	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BKP57_09495	COG2718	Belongs to the UPF0229 family
BKP57_09500	COG2766	serine protein kinase
BKP57_09505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKP57_09520	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BKP57_09530	COG3639	organic phosphonate transmembrane transporter activity
BKP57_09535	COG3639	organic phosphonate transmembrane transporter activity
BKP57_09540	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BKP57_09550	COG0613	PHP domain protein
BKP57_09555	COG4778	phosphonate C-P lyase system protein PhnL
BKP57_09560	COG3454	Phosphonate metabolism
BKP57_09565	COG4107	phosphonate C-P lyase system protein PhnK
BKP57_09570	COG3627	carbon phosphorus lyase activity
BKP57_09600	COG0395	ABC-type sugar transport system, permease component
BKP57_09630	COG0110	maltose O-acetyltransferase activity
BKP57_09640	COG0583	DNA-binding transcription factor activity
BKP57_09645	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BKP57_09650	COG1518	maintenance of DNA repeat elements
BKP57_09700	COG2116	formate transmembrane transporter activity
BKP57_09720	COG1280	lysine exporter protein (LysE YggA)
BKP57_09725	COG3403	YqcI/YcgG family
BKP57_09735	COG5577	PFAM Coat F domain
BKP57_09740	COG2814	Major facilitator Superfamily
BKP57_09750	COG2964	Protein conserved in bacteria
BKP57_09760	COG1760	l-serine dehydratase
BKP57_09765	COG1760	l-serine dehydratase
BKP57_09770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKP57_09775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKP57_09785	COG1131	(ABC) transporter
BKP57_09790	COG0842	Transport permease protein
BKP57_09795	COG1309	transcriptional regulator
BKP57_09805	COG1447	Phosphotransferase system cellobiose-specific component IIA
BKP57_09810	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP57_09815	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_09815	COG3711	transcriptional antiterminator
BKP57_09820	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP57_09825	COG1510	regulation of RNA biosynthetic process
BKP57_09830	COG1125	glycine betaine transport
BKP57_09830	COG0517	IMP dehydrogenase activity
BKP57_09835	COG1174	glycine betaine transport
BKP57_09840	COG1732	Glycine betaine
BKP57_09845	COG1174	glycine betaine transport
BKP57_09855	COG2190	(PTS) system
BKP57_09855	COG1263	PTS System
BKP57_09855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_09860	COG1486	melibiose metabolic process
BKP57_09865	COG1737	Transcriptional regulator
BKP57_09875	COG2056	Na+-H+ antiporter family
BKP57_09880	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKP57_09885	COG3588	fructose-bisphosphate aldolase
BKP57_09890	COG3408	Glycogen debranching enzyme
BKP57_09890	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BKP57_09895	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_09895	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_09895	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_09915	COG0726	polysaccharide deacetylase
BKP57_09935	COG0803	Belongs to the bacterial solute-binding protein 9 family
BKP57_09940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BKP57_09945	COG1121	(ABC) transporter
BKP57_09950	COG1028	Short-chain dehydrogenase reductase Sdr
BKP57_09955	COG1309	transcriptional regulator
BKP57_09965	COG3708	Transcriptional regulator
BKP57_09965	COG2207	Transcriptional regulator
BKP57_09970	COG1794	racemase activity, acting on amino acids and derivatives
BKP57_10000	COG1131	(ABC) transporter
BKP57_10050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP57_10065	COG2723	6-phospho-beta-galactosidase activity
BKP57_10070	COG1486	melibiose metabolic process
BKP57_10075	COG1447	Phosphotransferase system cellobiose-specific component IIA
BKP57_10080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_10080	COG3711	transcriptional antiterminator
BKP57_10110	COG3773	Cell wall hydrolase
BKP57_10120	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BKP57_10155	COG0586	Pfam SNARE associated Golgi protein
BKP57_10160	COG0688	phosphatidylethanolamine metabolic process
BKP57_10165	COG1183	phosphatidylcholine synthase activity
BKP57_10185	COG2027	D-alanyl-D-alanine carboxypeptidase
BKP57_10195	COG4932	domain protein
BKP57_10195	COG3266	domain, Protein
BKP57_10195	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BKP57_10205	COG1028	Short-chain dehydrogenase reductase Sdr
BKP57_10210	COG0406	alpha-ribazole phosphatase activity
BKP57_10225	COG0529	Catalyzes the synthesis of activated sulfate
BKP57_10230	COG3273	potassium ion transport
BKP57_10230	COG0471	metal ion transport
BKP57_10235	COG2046	Belongs to the sulfate adenylyltransferase family
BKP57_10260	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BKP57_10265	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BKP57_10270	COG0175	sulfate reduction
BKP57_10275	COG2076	Multidrug Resistance protein
BKP57_10280	COG2076	Multidrug Resistance protein
BKP57_10285	COG1309	transcriptional regulator
BKP57_10295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKP57_10300	COG0450	alkyl hydroperoxide reductase
BKP57_10305	COG1132	(ABC) transporter
BKP57_10315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKP57_10320	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BKP57_10325	COG4853	Protein conserved in bacteria
BKP57_10330	COG4863	YycH protein
BKP57_10335	COG5002	protein histidine kinase activity
BKP57_10340	COG0745	RESPONSE REGULATOR receiver
BKP57_10345	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BKP57_10350	COG0305	Participates in initiation and elongation during chromosome replication
BKP57_10355	COG0359	binds to the 23S rRNA
BKP57_10360	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BKP57_10375	COG0725	ABC transporter, periplasmic molybdate-binding protein
BKP57_10400	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BKP57_10405	COG0629	single-stranded DNA binding
BKP57_10410	COG0360	Binds together with S18 to 16S ribosomal RNA
BKP57_10415	COG0012	GTP binding
BKP57_10420	COG4481	Protein conserved in bacteria
BKP57_10425	COG0668	transmembrane transport
BKP57_10430	COG3949	Membrane
BKP57_10445	COG1475	DNA binding
BKP57_10450	COG1192	Involved in chromosome partitioning
BKP57_10455	COG1475	DNA binding
BKP57_10460	COG0357	Ribosomal RNA small subunit methyltransferase G
BKP57_10465	COG0445	tRNA wobble uridine modification
BKP57_10470	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BKP57_10475	COG1847	R3H domain protein
BKP57_10480	COG0706	membrane insertase activity
BKP57_10485	COG0594	ribonuclease P activity
BKP57_10490	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BKP57_10495	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BKP57_10500	COG0592	DNA-directed DNA polymerase activity
BKP57_10505	COG2501	S4 domain
BKP57_10510	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BKP57_10520	COG0187	DNA topoisomerase II activity
BKP57_10525	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BKP57_10530	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BKP57_10540	COG0517	IMP dehydrogenase activity
BKP57_10540	COG0516	GMP reductase activity
BKP57_10550	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BKP57_10555	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BKP57_10560	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BKP57_10570	COG2076	Multidrug Resistance protein
BKP57_10575	COG2076	Multidrug Resistance protein
BKP57_10580	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BKP57_10585	COG2011	ABC-type metal ion transport system permease component
BKP57_10590	COG1464	Belongs to the NlpA lipoprotein family
BKP57_10610	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BKP57_10615	COG1428	Deoxynucleoside kinase
BKP57_10620	COG1428	Deoxynucleoside kinase
BKP57_10630	COG1735	metal-dependent hydrolase with the TIM-barrel fold
BKP57_10645	COG3959	Transketolase, thiamine diphosphate binding domain
BKP57_10650	COG3958	Transketolase
BKP57_10660	COG1454	alcohol dehydrogenase
BKP57_10675	COG2390	Transcriptional regulator
BKP57_10695	COG1595	DNA-templated transcription, initiation
BKP57_10700	COG1737	Transcriptional regulator
BKP57_10710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_10710	COG1263	PTS System
BKP57_10715	COG1486	melibiose metabolic process
BKP57_10720	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKP57_10725	COG1876	peptidase activity
BKP57_10730	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BKP57_10740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BKP57_10745	COG0601	transmembrane transport
BKP57_10750	COG0747	negative chemotaxis
BKP57_10755	COG4608	Belongs to the ABC transporter superfamily
BKP57_10760	COG0444	Belongs to the ABC transporter superfamily
BKP57_10770	COG1418	mRNA catabolic process
BKP57_10775	COG2814	Major facilitator Superfamily
BKP57_10780	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BKP57_10785	COG1301	dicarboxylic acid transport
BKP57_10790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKP57_10805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BKP57_10805	COG1017	nitric oxide dioxygenase activity
BKP57_10810	COG1959	2 iron, 2 sulfur cluster binding
BKP57_10815	COG0693	protein deglycase activity
BKP57_10820	COG3858	chitin binding
BKP57_10820	COG1388	LysM domain
BKP57_10825	COG1335	isochorismatase
BKP57_10830	COG0590	tRNA wobble adenosine to inosine editing
BKP57_10840	COG0288	reversible hydration of carbon dioxide
BKP57_10845	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BKP57_10850	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BKP57_10855	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BKP57_10875	COG1982	Orn Lys Arg decarboxylase major
BKP57_10880	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BKP57_10885	COG3870	Protein conserved in bacteria
BKP57_10890	COG1728	Protein conserved in bacteria
BKP57_10895	COG0470	DNA polymerase III
BKP57_10900	COG1774	PSP1 C-terminal conserved region
BKP57_10905	COG4467	Involved in initiation control of chromosome replication
BKP57_10910	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BKP57_10915	COG2827	Endonuclease containing a URI domain
BKP57_10920	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BKP57_10925	COG2002	toxin-antitoxin pair type II binding
BKP57_10935	COG0084	hydrolase, TatD family'
BKP57_10940	COG3583	domain protein
BKP57_10940	COG3584	3D domain protein
BKP57_10950	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BKP57_10960	COG4466	Protein conserved in bacteria
BKP57_10970	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BKP57_10975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BKP57_10980	COG2088	sporulation resulting in formation of a cellular spore
BKP57_10985	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BKP57_10990	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BKP57_10995	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BKP57_11000	COG0193	aminoacyl-tRNA hydrolase activity
BKP57_11010	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BKP57_11015	COG2002	toxin-antitoxin pair type II binding
BKP57_11020	COG2244	polysaccharide biosynthetic process
BKP57_11025	COG3956	TIGRFAM MazG family protein
BKP57_11030	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BKP57_11050	COG1098	S1 RNA binding domain
BKP57_11065	COG2208	phosphoserine phosphatase activity
BKP57_11070	COG2304	oxidoreductase activity
BKP57_11075	COG0515	serine threonine protein kinase
BKP57_11080	COG0037	tRNA processing
BKP57_11090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKP57_11095	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BKP57_11100	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BKP57_11105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BKP57_11110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BKP57_11115	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BKP57_11120	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BKP57_11125	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BKP57_11130	COG1396	sequence-specific DNA binding
BKP57_11135	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BKP57_11215	COG1285	pathogenesis
BKP57_11225	COG3880	PFAM UvrB UvrC protein
BKP57_11230	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BKP57_11235	COG0542	response to heat
BKP57_11240	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BKP57_11245	COG4956	integral membrane protein (PIN domain superfamily)
BKP57_11250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BKP57_11255	COG1045	serine acetyltransferase
BKP57_11260	COG0215	cysteine-tRNA ligase activity
BKP57_11270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BKP57_11275	COG3688	RNA-binding protein containing a PIN domain
BKP57_11285	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BKP57_11290	COG0250	Participates in transcription elongation, termination and antitermination
BKP57_11295	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BKP57_11300	COG0081	regulation of translation
BKP57_11305	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BKP57_11315	COG2813	Specifically methylates the guanine in position
BKP57_11320	COG0085	RNA polymerase activity
BKP57_11325	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BKP57_11335	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BKP57_11340	COG0049	tRNA binding
BKP57_11345	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BKP57_11350	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BKP57_11360	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BKP57_11365	COG0088	Forms part of the polypeptide exit tunnel
BKP57_11370	COG0089	rRNA binding
BKP57_11375	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BKP57_11380	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BKP57_11385	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BKP57_11390	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BKP57_11395	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BKP57_11400	COG0255	Belongs to the universal ribosomal protein uL29 family
BKP57_11405	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BKP57_11410	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BKP57_11415	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BKP57_11420	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BKP57_11425	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BKP57_11430	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BKP57_11435	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BKP57_11440	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BKP57_11445	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BKP57_11450	COG1841	ribosomal large subunit assembly
BKP57_11455	COG0200	Binds to the 23S rRNA
BKP57_11460	COG0201	protein transport
BKP57_11465	COG0563	adenylate kinase activity
BKP57_11470	COG2163	COG2163 Ribosomal protein L14E L6E L27E
BKP57_11475	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BKP57_11480	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BKP57_11485	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BKP57_11490	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BKP57_11495	COG0202	RNA polymerase activity
BKP57_11500	COG0203	ribosomal protein L17
BKP57_11505	COG1122	ATPase activity
BKP57_11510	COG1122	ATPase activity
BKP57_11520	COG0101	tRNA pseudouridine synthase activity
BKP57_11525	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BKP57_11530	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BKP57_11545	COG1395	domain, Protein
BKP57_11595	COG3711	transcriptional antiterminator
BKP57_11600	COG2723	6-phospho-beta-galactosidase activity
BKP57_11605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_11605	COG1263	PTS System
BKP57_11605	COG2190	(PTS) system
BKP57_11650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKP57_11655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKP57_11660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKP57_11665	COG1120	ATPase activity
BKP57_11670	COG0492	ferredoxin-NADP+ reductase activity
BKP57_11675	COG1028	Short-chain dehydrogenase reductase Sdr
BKP57_11690	COG1349	DNA-binding transcription factor activity
BKP57_11700	COG0235	Class ii aldolase
BKP57_11705	COG1070	Carbohydrate kinase
BKP57_11715	COG2211	Major facilitator Superfamily
BKP57_11725	COG2271	Major facilitator Superfamily
BKP57_11750	COG1263	PTS System
BKP57_11750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_11765	COG0385	Bile acid
BKP57_11785	COG1979	alcohol dehydrogenase
BKP57_11790	COG1349	DNA-binding transcription factor activity
BKP57_11805	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BKP57_11810	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BKP57_11815	COG0235	Class ii aldolase
BKP57_11820	COG2130	NADP-dependent
BKP57_11825	COG0714	Associated with various cellular activities
BKP57_11830	COG4548	von Willebrand factor, type A
BKP57_11850	COG1295	ribonuclease BN
BKP57_11870	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKP57_11875	COG0489	protein tyrosine kinase activity
BKP57_11885	COG2194	sulfuric ester hydrolase activity
BKP57_11895	COG0726	polysaccharide deacetylase
BKP57_11940	COG4974	Belongs to the 'phage' integrase family
BKP57_11945	COG2856	Zn peptidase
BKP57_11995	COG2217	Heavy metal translocating P-type atpase
BKP57_12005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKP57_12015	COG1131	(ABC) transporter
BKP57_12020	COG0646	methionine synthase
BKP57_12020	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BKP57_12025	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BKP57_12030	COG2856	Zn peptidase
BKP57_12045	COG3677	Transposase
BKP57_12055	COG5434	Belongs to the glycosyl hydrolase 28 family
BKP57_12120	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BKP57_12135	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BKP57_12145	COG1595	DNA-templated transcription, initiation
BKP57_12150	COG5662	AntiSigma factor
BKP57_12155	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BKP57_12165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BKP57_12180	COG1349	DNA-binding transcription factor activity
BKP57_12190	COG0698	ribose 5-phosphate isomerase
BKP57_12220	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BKP57_12230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKP57_12255	COG3850	Histidine kinase
BKP57_12255	COG5002	protein histidine kinase activity
BKP57_12260	COG3344	reverse transcriptase
BKP57_12265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKP57_12275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BKP57_12290	COG1136	(ABC) transporter
BKP57_12295	COG0577	efflux transmembrane transporter activity
BKP57_12300	COG0745	RESPONSE REGULATOR receiver
BKP57_12305	COG2205	protein histidine kinase activity
BKP57_12325	COG2124	cytochrome p450
BKP57_12335	COG3655	Transcriptional regulator
BKP57_12340	COG3739	integral membrane protein
BKP57_12375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BKP57_12390	COG1555	photosystem II stabilization
BKP57_12390	COG1596	polysaccharide export
BKP57_12395	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BKP57_12420	COG4821	SIS domain
BKP57_12425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_12460	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BKP57_12465	COG2169	Transcriptional regulator
BKP57_12470	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BKP57_12490	COG2843	Capsule synthesis protein
BKP57_12515	COG0456	acetyltransferase
BKP57_12520	COG1280	lysine exporter protein (LysE YggA)
BKP57_12530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BKP57_12535	COG1136	(ABC) transporter
BKP57_12540	COG0577	efflux transmembrane transporter activity
BKP57_12545	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BKP57_12565	COG1028	Short-chain dehydrogenase reductase Sdr
BKP57_12570	COG3189	MarR family transcriptional regulator
BKP57_12585	COG1309	transcriptional regulator
BKP57_12600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BKP57_12610	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BKP57_12615	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BKP57_12620	COG0746	molybdenum cofactor guanylyltransferase activity
BKP57_12625	COG0521	Mo-molybdopterin cofactor biosynthetic process
BKP57_12630	COG0725	ABC transporter, periplasmic molybdate-binding protein
BKP57_12635	COG4149	molybdate abc transporter
BKP57_12640	COG0315	cyclic pyranopterin monophosphate synthase activity
BKP57_12650	COG2223	nitrite transmembrane transporter activity
BKP57_12655	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BKP57_12660	COG1140	nitrate reductase beta subunit
BKP57_12665	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BKP57_12670	COG2181	nitrate reductase activity
BKP57_12675	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BKP57_12680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BKP57_12700	COG0456	acetyltransferase
BKP57_12705	COG1136	(ABC) transporter
BKP57_12730	COG3634	alkyl hydroperoxide reductase activity
BKP57_12735	COG0450	alkyl hydroperoxide reductase
BKP57_12740	COG1115	amino acid carrier protein
BKP57_12745	COG4187	Peptidase family M20/M25/M40
BKP57_12750	COG2205	protein histidine kinase activity
BKP57_12755	COG0745	RESPONSE REGULATOR receiver
BKP57_12760	COG2311	Membrane
BKP57_12770	COG2723	6-phospho-beta-galactosidase activity
BKP57_12775	COG1940	carbohydrate kinase activity
BKP57_12785	COG0383	alpha-mannosidase activity
BKP57_12790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_12795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_12795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_12795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_12800	COG1131	(ABC) transporter
BKP57_12810	COG1733	regulation of RNA biosynthetic process
BKP57_12820	COG0666	response to abiotic stimulus
BKP57_12825	COG0456	acetyltransferase
BKP57_12830	COG0590	tRNA wobble adenosine to inosine editing
BKP57_12835	COG0318	PFAM AMP-dependent synthetase and ligase
BKP57_12840	COG1395	domain, Protein
BKP57_12865	COG1028	Short-chain dehydrogenase reductase Sdr
BKP57_12870	COG0109	protoheme IX farnesyltransferase activity
BKP57_12875	COG1253	flavin adenine dinucleotide binding
BKP57_12880	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BKP57_12885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKP57_12890	COG2226	methyltransferase
BKP57_12895	COG1328	CTP reductase activity
BKP57_12915	COG1801	Protein of unknown function DUF72
BKP57_12920	COG0395	ABC-type sugar transport system, permease component
BKP57_12925	COG1175	transmembrane transport
BKP57_12930	COG1653	transport
BKP57_12935	COG0366	Alpha amylase catalytic
BKP57_12940	COG1609	Transcriptional regulator
BKP57_12945	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BKP57_12955	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BKP57_12970	COG3766	membrane
BKP57_12980	COG1842	Phage shock protein A
BKP57_12990	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BKP57_13000	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BKP57_13005	COG1122	ATPase activity
BKP57_13010	COG4721	ABC-type cobalt transport system, permease component
BKP57_13020	COG0706	membrane insertase activity
BKP57_13040	COG0833	amino acid
BKP57_13045	COG1802	Transcriptional regulator
BKP57_13105	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BKP57_13140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BKP57_13145	COG4974	Belongs to the 'phage' integrase family
BKP57_13245	COG1484	DNA-dependent DNA replication
BKP57_13530	COG1695	Transcriptional regulator
BKP57_13545	COG1388	LysM domain
BKP57_13550	COG5002	protein histidine kinase activity
BKP57_13555	COG0745	RESPONSE REGULATOR receiver
BKP57_13570	COG3973	AAA domain
BKP57_13590	COG0616	signal peptide processing
BKP57_13595	COG1714	RDD family
BKP57_13600	COG1271	oxidase subunit
BKP57_13605	COG1294	oxidase, subunit
BKP57_13610	COG4988	ABC transporter
BKP57_13615	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BKP57_13620	COG0745	RESPONSE REGULATOR receiver
BKP57_13620	COG2972	Histidine kinase
BKP57_13625	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKP57_13625	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BKP57_13630	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BKP57_13630	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BKP57_13640	COG1131	(ABC) transporter
BKP57_13645	COG3559	Exporter of polyketide antibiotics
BKP57_13650	COG1132	(ABC) transporter
BKP57_13655	COG1114	Component of the transport system for branched-chain amino acids
BKP57_13660	COG1802	Transcriptional regulator
BKP57_13680	COG0535	radical SAM domain protein
BKP57_13690	COG0668	transmembrane transport
BKP57_13705	COG0400	carboxylic ester hydrolase activity
BKP57_13710	COG1846	Transcriptional regulator
BKP57_13720	COG2188	Transcriptional regulator
BKP57_13725	COG0366	Alpha amylase catalytic
BKP57_13730	COG1263	PTS System
BKP57_13730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_13740	COG1413	lyase activity
BKP57_13745	COG1607	acyl-coa hydrolase
BKP57_13765	COG3250	beta-galactosidase activity
BKP57_13770	COG0531	amino acid
BKP57_13785	COG1131	(ABC) transporter
BKP57_13810	COG5444	nuclease activity
BKP57_13815	COG0346	lactoylglutathione lyase activity
BKP57_13820	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BKP57_13825	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BKP57_13830	COG0083	homoserine kinase activity
BKP57_13835	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BKP57_13840	COG0460	homoserine dehydrogenase
BKP57_13850	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BKP57_13855	COG1620	l-lactate permease
BKP57_13860	COG2186	Transcriptional regulator
BKP57_13865	COG0247	lactate metabolic process
BKP57_13870	COG1139	Iron-sulfur cluster binding protein
BKP57_13875	COG1556	Lactate utilization protein
BKP57_13895	COG0477	Major facilitator Superfamily
BKP57_13900	COG0789	Transcriptional regulator
BKP57_13905	COG0352	thiamine-phosphate diphosphorylase activity
BKP57_13910	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BKP57_13925	COG0444	Belongs to the ABC transporter superfamily
BKP57_13930	COG4608	Belongs to the ABC transporter superfamily
BKP57_13935	COG0747	negative chemotaxis
BKP57_13970	COG0737	Belongs to the 5'-nucleotidase family
BKP57_13970	COG1525	nuclease
BKP57_13970	COG4085	toxin activity
BKP57_13975	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BKP57_13980	COG0157	Belongs to the NadC ModD family
BKP57_13985	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BKP57_13990	COG1104	cysteine desulfurase activity
BKP57_13995	COG1827	regulation of RNA biosynthetic process
BKP57_14010	COG3104	oligopeptide transport
BKP57_14030	COG4145	pantothenate transmembrane transporter activity
BKP57_14035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BKP57_14040	COG0693	protein deglycase activity
BKP57_14085	COG5506	Protein of unknown function (DUF1694)
BKP57_14125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKP57_14135	COG2201	protein-glutamate methylesterase activity
BKP57_14145	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BKP57_14155	COG4869	propanediol catabolic process
BKP57_14165	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_14165	COG1454	alcohol dehydrogenase
BKP57_14175	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BKP57_14195	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BKP57_14200	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BKP57_14205	COG4820	ethanolamine utilization protein (EutJ)
BKP57_14210	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
BKP57_14220	COG0708	Exodeoxyribonuclease III
BKP57_14225	COG1725	Transcriptional regulator
BKP57_14230	COG1131	(ABC) transporter
BKP57_14245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP57_14255	COG1136	(ABC) transporter
BKP57_14260	COG0159	tryptophan synthase activity
BKP57_14265	COG0133	tryptophan synthase activity
BKP57_14270	COG0135	phosphoribosylanthranilate isomerase activity
BKP57_14275	COG0134	indole-3-glycerol-phosphate synthase activity
BKP57_14280	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BKP57_14290	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BKP57_14300	COG1181	Belongs to the D-alanine--D-alanine ligase family
BKP57_14305	COG0778	Nitroreductase
BKP57_14335	COG0519	Catalyzes the synthesis of GMP from XMP
BKP57_14340	COG0840	transmembrane signaling receptor activity
BKP57_14360	COG1136	(ABC) transporter
BKP57_14380	COG0656	L-ascorbic acid biosynthetic process
BKP57_14390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BKP57_14400	COG1304	FMN binding
BKP57_14405	COG4876	unkown
BKP57_14410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BKP57_14415	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BKP57_14420	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKP57_14425	COG4605	iron ion homeostasis
BKP57_14430	COG4604	ABC transporter, ATP-binding protein
BKP57_14435	COG4607	ABC-type enterochelin transport system periplasmic component
BKP57_14445	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BKP57_14450	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BKP57_14450	COG0140	phosphoribosyl-ATP diphosphatase activity
BKP57_14455	COG0107	imidazoleglycerol-phosphate synthase activity
BKP57_14460	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BKP57_14465	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BKP57_14470	COG0131	Imidazoleglycerol-phosphate dehydratase
BKP57_14475	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BKP57_14480	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BKP57_14485	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BKP57_14505	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BKP57_14515	COG1126	abc transporter atp-binding protein
BKP57_14520	COG0765	amino acid transport
BKP57_14525	COG0765	amino acid transport
BKP57_14535	COG2610	gluconate transmembrane transporter activity
BKP57_14565	COG3381	protein complex oligomerization
BKP57_14570	COG0243	molybdopterin cofactor binding
BKP57_14575	COG0437	4 iron, 4 sulfur cluster binding
BKP57_14590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKP57_14595	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BKP57_14600	COG0673	inositol 2-dehydrogenase activity
BKP57_14605	COG1876	peptidase activity
BKP57_14610	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BKP57_14615	COG2839	Protein conserved in bacteria
BKP57_14620	COG1335	isochorismatase
BKP57_14630	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BKP57_14640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BKP57_14645	COG0765	amino acid transport
BKP57_14650	COG1126	abc transporter atp-binding protein
BKP57_14655	COG0386	Belongs to the glutathione peroxidase family
BKP57_14660	COG0840	transmembrane signaling receptor activity
BKP57_14670	COG1454	alcohol dehydrogenase
BKP57_14675	COG3254	rhamnose metabolic process
BKP57_14680	COG2814	Major facilitator Superfamily
BKP57_14685	COG1070	Carbohydrate kinase
BKP57_14690	COG4806	L-rhamnose isomerase
BKP57_14695	COG0235	Class ii aldolase
BKP57_14700	COG1349	DNA-binding transcription factor activity
BKP57_14710	COG0840	transmembrane signaling receptor activity
BKP57_14720	COG0300	oxidoreductase activity
BKP57_14725	COG3829	transcription factor binding
BKP57_14740	COG1268	BioY protein
BKP57_14750	COG1937	Protein conserved in bacteria
BKP57_14755	COG2217	Heavy metal translocating P-type atpase
BKP57_14765	COG1278	Cold shock
BKP57_14775	COG0432	Pfam Uncharacterised protein family UPF0047
BKP57_14785	COG0791	NLP P60 protein
BKP57_14785	COG1388	LysM domain
BKP57_14790	COG3944	biosynthesis protein
BKP57_14795	COG0489	protein tyrosine kinase activity
BKP57_14800	COG4464	protein tyrosine phosphatase activity
BKP57_14815	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BKP57_14820	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BKP57_14825	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BKP57_14835	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BKP57_14870	COG0686	Belongs to the AlaDH PNT family
BKP57_14880	COG1316	TRANSCRIPTIONal
BKP57_14890	COG3279	Response regulator of the LytR AlgR family
BKP57_14930	COG1414	Transcriptional regulator
BKP57_14935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKP57_14945	COG4948	Mandelate Racemase Muconate Lactonizing
BKP57_14950	COG2814	Major facilitator Superfamily
BKP57_14960	COG1028	Short-chain dehydrogenase reductase Sdr
BKP57_14965	COG3386	PFAM SMP-30 Gluconolaconase
BKP57_14975	COG3290	protein histidine kinase activity
BKP57_14980	COG4565	transcriptional regulatory protein
BKP57_14985	COG2851	Citrate transporter
BKP57_15025	COG3732	PTS system glucitol sorbitol-specific
BKP57_15040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_15040	COG3711	transcriptional antiterminator
BKP57_15045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_15045	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_15045	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_15055	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_15060	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BKP57_15065	COG2188	Transcriptional regulator
BKP57_15070	COG1486	melibiose metabolic process
BKP57_15075	COG3394	polysaccharide catabolic process
BKP57_15080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_15080	COG1263	PTS System
BKP57_15085	COG3344	reverse transcriptase
BKP57_15090	COG1595	DNA-templated transcription, initiation
BKP57_15100	COG1131	(ABC) transporter
BKP57_15115	COG3876	Protein conserved in bacteria
BKP57_15125	COG1737	Transcriptional regulator
BKP57_15135	COG0456	acetyltransferase
BKP57_15140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BKP57_15145	COG0384	phenazine biosynthesis protein PhzF
BKP57_15150	COG0840	transmembrane signaling receptor activity
BKP57_15155	COG1757	Na H antiporter
BKP57_15170	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BKP57_15200	COG0463	Glycosyl transferase, family 2
BKP57_15210	COG4485	Bacterial membrane protein, YfhO
BKP57_15230	COG0318	PFAM AMP-dependent synthetase and ligase
BKP57_15240	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKP57_15245	COG1024	Enoyl-CoA hydratase
BKP57_15255	COG1960	acyl-CoA dehydrogenase activity
BKP57_15260	COG0824	Thioesterase
BKP57_15275	COG1414	Transcriptional regulator
BKP57_15280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BKP57_15290	COG0179	Fumarylacetoacetate (FAA) hydrolase
BKP57_15345	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BKP57_15350	COG0523	cobalamin synthesis protein
BKP57_15370	COG1136	(ABC) transporter
BKP57_15375	COG2205	protein histidine kinase activity
BKP57_15380	COG0745	RESPONSE REGULATOR receiver
BKP57_15390	COG2337	Toxic component of a toxin-antitoxin (TA) module
BKP57_15420	COG3409	Peptidoglycan-binding domain 1 protein
BKP57_15425	COG3409	Peptidoglycan-binding domain 1 protein
BKP57_15450	COG2337	Toxic component of a toxin-antitoxin (TA) module
BKP57_15470	COG3409	Peptidoglycan-binding domain 1 protein
BKP57_15495	COG0717	Belongs to the dCTP deaminase family
BKP57_15500	COG1396	sequence-specific DNA binding
BKP57_15510	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BKP57_15525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BKP57_15530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKP57_15535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BKP57_15580	COG0702	epimerase
BKP57_15615	COG3715	PTS system
BKP57_15620	COG3716	PTS system mannose fructose sorbose family IID component
BKP57_15625	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BKP57_15640	COG1396	sequence-specific DNA binding
BKP57_15660	COG1929	Belongs to the glycerate kinase type-1 family
BKP57_15665	COG2610	gluconate transmembrane transporter activity
BKP57_15670	COG3835	regulator
BKP57_15675	COG0018	arginyl-trna synthetase
BKP57_15685	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BKP57_15695	COG0549	Belongs to the carbamate kinase family
BKP57_15700	COG1438	arginine binding
BKP57_15710	COG3414	Phosphotransferase system galactitol-specific IIB component
BKP57_15720	COG1063	alcohol dehydrogenase
BKP57_15725	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BKP57_15735	COG4509	Sortase family
BKP57_15740	COG1120	ATPase activity
BKP57_15755	COG5386	Cell surface protein
BKP57_15760	COG5386	Cell surface protein
BKP57_15765	COG5386	Cell surface protein
BKP57_15770	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BKP57_15775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BKP57_15795	COG3711	transcriptional antiterminator
BKP57_15795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_15800	COG1486	melibiose metabolic process
BKP57_15810	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BKP57_15820	COG3876	Protein conserved in bacteria
BKP57_15845	COG1215	transferase activity, transferring glycosyl groups
BKP57_15855	COG0006	proline dipeptidase activity
BKP57_15860	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BKP57_15865	COG0583	DNA-binding transcription factor activity
BKP57_15880	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BKP57_15890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKP57_15910	COG3414	Phosphotransferase system galactitol-specific IIB component
BKP57_15915	COG3775	system Galactitol-specific IIC component
BKP57_15930	COG1105	Belongs to the carbohydrate kinase PfkB family
BKP57_15935	COG0235	Class ii aldolase
BKP57_15950	COG0492	ferredoxin-NADP+ reductase activity
BKP57_15960	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BKP57_15965	COG3396	Phenylacetate-CoA oxygenase
BKP57_15980	COG2151	metal-sulfur cluster biosynthetic enzyme
BKP57_15995	COG1024	Enoyl-CoA hydratase
BKP57_16000	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_16005	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKP57_16010	COG0183	Belongs to the thiolase family
BKP57_16015	COG1024	Enoyl-CoA hydratase
BKP57_16020	COG3327	negative regulation of DNA-templated transcription, initiation
BKP57_16040	COG4948	Mandelate Racemase Muconate Lactonizing
BKP57_16055	COG4977	sequence-specific DNA binding
BKP57_16055	COG1917	Cupin 2, conserved barrel domain protein
BKP57_16060	COG1454	alcohol dehydrogenase
BKP57_16060	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_16065	COG3279	Response regulator of the LytR AlgR family
BKP57_16100	COG1309	transcriptional regulator
BKP57_16105	COG4708	membrane
BKP57_16110	COG1028	Short-chain dehydrogenase reductase Sdr
BKP57_16135	COG2508	Transcriptional regulator
BKP57_16145	COG0145	ligase activity
BKP57_16155	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BKP57_16180	COG4126	flavin adenine dinucleotide binding
BKP57_16185	COG0697	spore germination
BKP57_16200	COG3290	protein histidine kinase activity
BKP57_16205	COG4565	transcriptional regulatory protein
BKP57_16230	COG0789	Transcriptional regulator
BKP57_16235	COG1764	response to oxidative stress
BKP57_16240	COG1609	Transcriptional regulator
BKP57_16250	COG1621	beta-fructofuranosidase activity
BKP57_16255	COG1940	carbohydrate kinase activity
BKP57_16260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_16260	COG1263	PTS System
BKP57_16265	COG1263	PTS System
BKP57_16265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_16285	COG3142	Participates in the control of copper homeostasis
BKP57_16300	COG1523	belongs to the glycosyl hydrolase 13 family
BKP57_16305	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BKP57_16310	COG0402	S-adenosylhomocysteine deaminase activity
BKP57_16320	COG3775	system Galactitol-specific IIC component
BKP57_16325	COG3414	Phosphotransferase system galactitol-specific IIB component
BKP57_16330	COG1999	signal sequence binding
BKP57_16335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BKP57_16355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKP57_16365	COG2022	thiamine diphosphate biosynthetic process
BKP57_16370	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BKP57_16375	COG1119	ATPase activity
BKP57_16380	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BKP57_16385	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BKP57_16390	COG1918	ferrous iron import across plasma membrane
BKP57_16390	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BKP57_16395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKP57_16400	COG3223	Belongs to the PsiE family
BKP57_16410	COG0745	RESPONSE REGULATOR receiver
BKP57_16415	COG5002	protein histidine kinase activity
BKP57_16425	COG3764	Sortase (surface protein transpeptidase)
BKP57_16430	COG0436	Aminotransferase
BKP57_16435	COG1309	transcriptional regulator
BKP57_16450	COG0183	Belongs to the thiolase family
BKP57_16460	COG0318	PFAM AMP-dependent synthetase and ligase
BKP57_16465	COG0318	PFAM AMP-dependent synthetase and ligase
BKP57_16490	COG1063	alcohol dehydrogenase
BKP57_16495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKP57_16510	COG2706	6-phosphogluconolactonase activity
BKP57_16515	COG3711	transcriptional antiterminator
BKP57_16520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_16535	COG1735	metal-dependent hydrolase with the TIM-barrel fold
BKP57_16545	COG4821	SIS domain
BKP57_16555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BKP57_16560	COG1737	Transcriptional regulator
BKP57_16565	COG1234	tRNA 3'-trailer cleavage
BKP57_16585	COG0444	Belongs to the ABC transporter superfamily
BKP57_16590	COG4608	Belongs to the ABC transporter superfamily
BKP57_16595	COG2814	Major facilitator Superfamily
BKP57_16600	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BKP57_16615	COG1473	amidohydrolase
BKP57_16620	COG1288	antiporter activity
BKP57_16625	COG4948	Mandelate Racemase Muconate Lactonizing
BKP57_16630	COG2985	domain, Protein
BKP57_16630	COG0490	domain, Protein
BKP57_16635	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BKP57_16645	COG3711	transcriptional antiterminator
BKP57_16650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BKP57_16650	COG1263	PTS System
BKP57_16650	COG2190	(PTS) system
BKP57_16655	COG1486	melibiose metabolic process
BKP57_16660	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_16665	COG3711	transcriptional antiterminator
BKP57_16665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_16670	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_16670	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BKP57_16670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_16675	COG1482	cell wall glycoprotein biosynthetic process
BKP57_16680	COG3263	regulation of cellular component size
BKP57_16685	COG0656	L-ascorbic acid biosynthetic process
BKP57_16695	COG0129	dihydroxy-acid dehydratase activity
BKP57_16700	COG0028	Belongs to the TPP enzyme family
BKP57_16705	COG0440	acetolactate synthase activity
BKP57_16710	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BKP57_16715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BKP57_16720	COG0473	3-isopropylmalate dehydrogenase activity
BKP57_16725	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BKP57_16730	COG0066	3-isopropylmalate dehydratase activity
BKP57_16735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BKP57_16740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BKP57_16750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BKP57_16755	COG0366	Alpha amylase catalytic
BKP57_16760	COG2207	Transcriptional regulator
BKP57_16760	COG1917	Cupin 2, conserved barrel domain protein
BKP57_16780	COG5426	von Willebrand factor, type A
BKP57_16785	COG1940	carbohydrate kinase activity
BKP57_16790	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BKP57_16800	COG1476	TRANSCRIPTIONal
BKP57_16820	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BKP57_16825	COG2076	Multidrug Resistance protein
BKP57_16835	COG0463	Glycosyl transferase, family 2
BKP57_16855	COG4608	Belongs to the ABC transporter superfamily
BKP57_16860	COG0601	transmembrane transport
BKP57_16875	COG0367	asparagine synthase
BKP57_16885	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BKP57_16890	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BKP57_16895	COG2376	Dihydroxyacetone kinase
BKP57_16900	COG1461	Dihydroxyacetone kinase
BKP57_16905	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BKP57_16915	COG1966	Carbon starvation protein
BKP57_16920	COG3279	Response regulator of the LytR AlgR family
BKP57_16925	COG3275	phosphorelay sensor kinase activity
BKP57_16930	COG1522	sequence-specific DNA binding
BKP57_16940	COG2059	Chromate
BKP57_16945	COG2059	Chromate
BKP57_16950	COG0561	phosphatase activity
BKP57_16955	COG0745	RESPONSE REGULATOR receiver
BKP57_16965	COG2996	Protein conserved in bacteria
BKP57_16970	COG1028	Short-chain dehydrogenase reductase Sdr
BKP57_16975	COG1971	Probably functions as a manganese efflux pump
BKP57_16995	COG1473	amidohydrolase
BKP57_17055	COG2226	methyltransferase
BKP57_17075	COG1331	Highly conserved protein containing a thioredoxin domain
BKP57_17080	COG1595	DNA-templated transcription, initiation
BKP57_17090	COG1316	TRANSCRIPTIONal
BKP57_17110	COG3639	organic phosphonate transmembrane transporter activity
BKP57_17115	COG3639	organic phosphonate transmembrane transporter activity
BKP57_17120	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BKP57_17130	COG0788	formyltetrahydrofolate deformylase activity
BKP57_17140	COG2391	methyltransferase activity
BKP57_17180	COG2182	Extracellular solute-binding protein
BKP57_17185	COG1175	transmembrane transport
BKP57_17190	COG3833	ABC-type maltose transport systems, permease component
BKP57_17200	COG1609	Transcriptional regulator
BKP57_17205	COG1486	melibiose metabolic process
BKP57_17225	COG1447	Phosphotransferase system cellobiose-specific component IIA
BKP57_17235	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BKP57_17240	COG2971	BadF BadG BcrA BcrD
BKP57_17250	COG1472	Belongs to the glycosyl hydrolase 3 family
BKP57_17255	COG1653	transport
BKP57_17260	COG1175	transmembrane transport
BKP57_17265	COG0395	ABC-type sugar transport system, permease component
BKP57_17310	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_17315	COG0840	transmembrane signaling receptor activity
BKP57_17320	COG0840	transmembrane signaling receptor activity
BKP57_17325	COG1368	sulfuric ester hydrolase activity
BKP57_17335	COG2807	transmembrane transport
BKP57_17340	COG2814	Major facilitator Superfamily
BKP57_17345	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BKP57_17350	COG0471	metal ion transport
BKP57_17355	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BKP57_17360	COG2814	Major facilitator Superfamily
BKP57_17365	COG0561	phosphatase activity
BKP57_17375	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_17385	COG0768	penicillin binding
BKP57_17390	COG1316	TRANSCRIPTIONal
BKP57_17410	COG0681	Belongs to the peptidase S26 family
BKP57_17425	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BKP57_17430	COG0363	glucosamine-6-phosphate deaminase activity
BKP57_17435	COG1739	Uncharacterized protein family UPF0029
BKP57_17445	COG2197	response regulator
BKP57_17450	COG1307	EDD domain protein, DegV family
BKP57_17455	COG2197	response regulator
BKP57_17465	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BKP57_17470	COG1040	competence protein
BKP57_17490	COG1256	bacterial-type flagellum assembly
BKP57_17490	COG4786	Flagellar basal body rod
BKP57_17495	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BKP57_17505	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BKP57_17510	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BKP57_17515	COG1334	flagellar protein FlaG
BKP57_17520	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BKP57_17525	COG1516	flagellar protein fliS
BKP57_17535	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BKP57_17540	COG0653	protein targeting
BKP57_17545	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BKP57_17555	COG2884	Cell division ATP-binding protein ftsE
BKP57_17560	COG2177	Part of the ABC transporter FtsEX involved in
BKP57_17565	COG0739	heme binding
BKP57_17570	COG3409	Peptidoglycan-binding domain 1 protein
BKP57_17570	COG0793	Belongs to the peptidase S41A family
BKP57_17580	COG0726	polysaccharide deacetylase
BKP57_17585	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BKP57_17590	COG0556	nucleotide-excision repair
BKP57_17595	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BKP57_17600	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BKP57_17605	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BKP57_17610	COG1983	PspC domain protein
BKP57_17615	COG1950	PFAM Membrane protein of
BKP57_17620	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BKP57_17625	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BKP57_17630	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BKP57_17635	COG0546	phosphoglycolate phosphatase activity
BKP57_17640	COG0110	maltose O-acetyltransferase activity
BKP57_17645	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BKP57_17650	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BKP57_17655	COG0457	Tetratricopeptide repeat
BKP57_17660	COG0492	ferredoxin-NADP+ reductase activity
BKP57_17665	COG1051	belongs to the nudix hydrolase family
BKP57_17670	COG1660	Displays ATPase and GTPase activities
BKP57_17675	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BKP57_17680	COG1481	regulation of sporulation
BKP57_17685	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_17690	COG0740	serine-type endopeptidase activity
BKP57_17700	COG4974	Belongs to the 'phage' integrase family
BKP57_17710	COG0582	viral genome integration into host DNA
BKP57_17810	COG1914	H( )-stimulated, divalent metal cation uptake system
BKP57_17815	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BKP57_17820	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BKP57_17825	COG1984	allophanate hydrolase subunit 2
BKP57_17850	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BKP57_17855	COG0710	3-dehydroquinate dehydratase activity
BKP57_17865	COG2112	serine threonine protein kinase
BKP57_17870	COG0328	RNA-DNA hybrid ribonuclease activity
BKP57_17875	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BKP57_17895	COG0126	phosphoglycerate kinase activity
BKP57_17900	COG0149	triose-phosphate isomerase activity
BKP57_17905	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BKP57_17910	COG0148	phosphopyruvate hydratase activity
BKP57_17915	COG1484	DNA-dependent DNA replication
BKP57_17935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BKP57_17945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BKP57_17950	COG1116	anion transmembrane transporter activity
BKP57_17955	COG0084	hydrolase, TatD family'
BKP57_17975	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BKP57_17980	COG1647	Serine aminopeptidase, S33
BKP57_17985	COG0557	exoribonuclease II activity
BKP57_17990	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BKP57_18010	COG0517	IMP dehydrogenase activity
BKP57_18015	COG1272	protein, Hemolysin III
BKP57_18025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKP57_18030	COG0586	Pfam SNARE associated Golgi protein
BKP57_18050	COG4758	membrane
BKP57_18055	COG4585	Histidine kinase
BKP57_18060	COG2197	response regulator
BKP57_18065	COG4129	membrane
BKP57_18070	COG2224	Isocitrate lyase
BKP57_18075	COG0791	NLP P60 protein
BKP57_18075	COG3883	PFAM NLP P60 protein
BKP57_18085	COG2076	Multidrug Resistance protein
BKP57_18090	COG2076	Multidrug Resistance protein
BKP57_18100	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BKP57_18105	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BKP57_18110	COG0735	belongs to the Fur family
BKP57_18115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BKP57_18120	COG1121	(ABC) transporter
BKP57_18130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BKP57_18135	COG0431	NADPH-dependent FMN reductase
BKP57_18140	COG1024	Enoyl-CoA hydratase
BKP57_18140	COG1250	3-hydroxyacyl-CoA dehydrogenase
BKP57_18145	COG0183	Belongs to the thiolase family
BKP57_18150	COG1960	acyl-CoA dehydrogenase activity
BKP57_18155	COG1393	Belongs to the ArsC family
BKP57_18160	COG0509	glycine decarboxylation via glycine cleavage system
BKP57_18165	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BKP57_18170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP57_18175	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BKP57_18180	COG2011	ABC-type metal ion transport system permease component
BKP57_18185	COG1464	Belongs to the NlpA lipoprotein family
BKP57_18190	COG0396	ATPase activity
BKP57_18195	COG0719	Fe-S assembly protein
BKP57_18200	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BKP57_18205	COG0822	iron-sulfur transferase activity
BKP57_18210	COG0719	Fe-S assembly protein
BKP57_18220	COG2076	Multidrug Resistance protein
BKP57_18245	COG3284	Transcriptional regulator
BKP57_18250	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BKP57_18255	COG0022	dehydrogenase e1 component
BKP57_18260	COG0508	dehydrogenase complex catalyzes the overall conversion of
BKP57_18270	COG3227	Zinc metalloprotease (Elastase)
BKP57_18275	COG1063	alcohol dehydrogenase
BKP57_18310	COG0745	RESPONSE REGULATOR receiver
BKP57_18315	COG3850	Histidine kinase
BKP57_18315	COG5002	protein histidine kinase activity
BKP57_18325	COG0501	Belongs to the peptidase M48B family
BKP57_18335	COG1295	ribonuclease BN
BKP57_18365	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BKP57_18370	COG1368	sulfuric ester hydrolase activity
BKP57_18380	COG0431	NADPH-dependent FMN reductase
BKP57_18385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BKP57_18410	COG0204	Acyl-transferase
BKP57_18415	COG0477	Major facilitator Superfamily
BKP57_18420	COG0583	DNA-binding transcription factor activity
BKP57_18435	COG1012	belongs to the aldehyde dehydrogenase family
BKP57_18445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKP57_18470	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BKP57_18485	COG2329	Antibiotic biosynthesis monooxygenase
BKP57_18490	COG2202	Pas domain
BKP57_18490	COG1366	Belongs to the anti-sigma-factor antagonist family
BKP57_18495	COG3425	synthase
BKP57_18505	COG1131	(ABC) transporter
BKP57_18530	COG1228	amidohydrolase
BKP57_18550	COG2076	Multidrug Resistance protein
BKP57_18565	COG1408	metallophosphoesterase
BKP57_18575	COG5564	TIM-barrel signal transduction protein
BKP57_18585	COG5564	TIM-barrel signal transduction protein
BKP57_18595	COG1533	DNA photolyase activity
BKP57_18630	COG2391	methyltransferase activity
BKP57_18640	COG1349	DNA-binding transcription factor activity
BKP57_18650	COG2268	Band 7 protein
BKP57_18655	COG1585	Membrane protein implicated in regulation of membrane protease activity
BKP57_18660	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKP57_18670	COG1175	transmembrane transport
BKP57_18685	COG0584	glycerophosphoryl diester phosphodiesterase
BKP57_18690	COG0584	glycerophosphoryl diester phosphodiesterase
BKP57_18800	COG1063	alcohol dehydrogenase
BKP57_18810	COG0446	pyridine nucleotide-disulphide oxidoreductase
BKP57_18820	COG1301	dicarboxylic acid transport
BKP57_18825	COG2814	Major facilitator Superfamily
BKP57_18830	COG5504	Zn-dependent protease
BKP57_18835	COG2226	methyltransferase
BKP57_18865	COG0420	3'-5' exonuclease activity
BKP57_18870	COG0419	ATPase involved in DNA repair
BKP57_18875	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKP57_18880	COG2188	Transcriptional regulator
BKP57_18900	COG1735	metal-dependent hydrolase with the TIM-barrel fold
BKP57_18905	COG0626	cystathionine gamma-synthase activity
BKP57_18915	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BKP57_18920	COG0667	Aldo Keto reductase
BKP57_18925	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BKP57_18930	COG2027	D-alanyl-D-alanine carboxypeptidase
BKP57_18950	COG0318	PFAM AMP-dependent synthetase and ligase
BKP57_18955	COG1252	NADH dehydrogenase
BKP57_18960	COG2720	vancomycin resistance protein
BKP57_18965	COG2353	YceI-like domain
BKP57_18975	COG3069	C4-dicarboxylate transmembrane transporter activity
BKP57_18990	COG0003	Pfam Anion-transporting ATPase
BKP57_18995	COG0604	alcohol dehydrogenase
BKP57_19000	COG1301	dicarboxylic acid transport
BKP57_19005	COG2323	membrane
BKP57_19020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BKP57_19045	COG0778	Nitroreductase
BKP57_19055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BKP57_19060	COG3300	MHYT domain
BKP57_19060	COG5001	Diguanylate cyclase
BKP57_19065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BKP57_19085	COG0436	Aminotransferase
BKP57_19090	COG2962	Rard protein
BKP57_19105	COG1408	metallophosphoesterase
BKP57_19115	COG0640	Transcriptional regulator
BKP57_19120	COG0517	IMP dehydrogenase activity
BKP57_19125	COG2171	N-acyltransferase activity
BKP57_19130	COG1473	amidohydrolase
BKP57_19140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP57_19145	COG1132	(ABC) transporter
BKP57_19150	COG1132	(ABC) transporter
BKP57_19155	COG0569	domain protein
BKP57_19160	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BKP57_19170	COG0561	phosphatase activity
BKP57_19175	COG0242	peptide deformylase activity
BKP57_19190	COG0022	dehydrogenase e1 component
BKP57_19210	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BKP57_19215	COG0726	polysaccharide deacetylase
BKP57_19220	COG4476	Belongs to the UPF0223 family
BKP57_19225	COG4493	Belongs to the UPF0637 family
BKP57_19235	COG0483	inositol monophosphate 1-phosphatase activity
BKP57_19260	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BKP57_19265	COG4838	Belongs to the UPF0358 family
BKP57_19270	COG0772	Belongs to the SEDS family
BKP57_19275	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BKP57_19280	COG1612	heme a metabolic process
BKP57_19285	COG0109	protoheme IX farnesyltransferase activity
BKP57_19300	COG1845	cytochrome c oxidase, subunit III
BKP57_19310	COG3336	cytochrome c oxidase
BKP57_19330	COG2340	Cysteine-rich secretory protein family
BKP57_19345	COG3679	Belongs to the UPF0342 family
BKP57_19350	COG4471	UPF0298 protein
BKP57_19355	COG0742	ribosomal rna small subunit methyltransferase
BKP57_19360	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BKP57_19365	COG3314	Sporulation integral membrane protein YlbJ
BKP57_19370	COG3480	Lon protease (S16) C-terminal proteolytic domain
BKP57_19375	COG1323	Belongs to the UPF0348 family
BKP57_19380	COG1399	metal-binding, possibly nucleic acid-binding protein
BKP57_19385	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BKP57_19395	COG0454	-acetyltransferase
BKP57_19405	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BKP57_19410	COG2001	Belongs to the MraZ family
BKP57_19415	COG0275	rRNA processing
BKP57_19420	COG4839	cell division protein FtsL
BKP57_19430	COG0768	penicillin binding
BKP57_19435	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BKP57_19440	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BKP57_19445	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BKP57_19450	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BKP57_19455	COG0772	Belongs to the SEDS family
BKP57_19460	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BKP57_19465	COG0849	cell division
BKP57_19470	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BKP57_19475	COG3344	reverse transcriptase
BKP57_19485	COG1191	sigma factor activity
BKP57_19490	COG1191	sigma factor activity
BKP57_19495	COG1873	PFAM PRC-barrel domain
BKP57_19505	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BKP57_19510	COG1799	cell septum assembly
BKP57_19515	COG0762	integral membrane protein
BKP57_19520	COG2302	S4 RNA-binding domain
BKP57_19525	COG3599	regulation of cell shape
BKP57_19530	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BKP57_19535	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BKP57_19540	COG0564	pseudouridine synthase activity
BKP57_19545	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BKP57_19550	COG0540	Belongs to the ATCase OTCase family
BKP57_19555	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BKP57_19560	COG0505	Belongs to the CarA family
BKP57_19570	COG0543	2 iron, 2 sulfur cluster binding
BKP57_19575	COG0167	dihydroorotate dehydrogenase activity
BKP57_19580	COG0284	orotidine-5'-phosphate decarboxylase activity
BKP57_19585	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BKP57_19590	COG2226	methyltransferase
BKP57_19595	COG0583	DNA-binding transcription factor activity
BKP57_19600	COG1764	response to oxidative stress
BKP57_19610	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BKP57_19615	COG1561	YicC-like family, N-terminal region
BKP57_19620	COG2052	Domain of unknown function (DUF370)
BKP57_19625	COG0194	GDP metabolic process
BKP57_19630	COG1758	RNA polymerase activity
BKP57_19635	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BKP57_19640	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BKP57_19645	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BKP57_19650	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BKP57_19650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BKP57_19655	COG0631	protein serine/threonine phosphatase activity
BKP57_19660	COG2815	serine threonine protein kinase
BKP57_19660	COG0515	serine threonine protein kinase
BKP57_19665	COG1162	GTPase activity
BKP57_19670	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BKP57_19675	COG1564	THIamine pyrophosphokinase
BKP57_19685	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BKP57_19700	COG1302	Protein conserved in bacteria
BKP57_19705	COG1461	Dihydroxyacetone kinase
BKP57_19715	COG1760	l-serine dehydratase
BKP57_19720	COG1760	l-serine dehydratase
BKP57_19725	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BKP57_19730	COG1349	DNA-binding transcription factor activity
BKP57_19735	COG0416	fatty acid biosynthetic process
BKP57_19740	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BKP57_19745	COG1028	Short-chain dehydrogenase reductase Sdr
BKP57_19750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BKP57_19755	COG0571	ribonuclease III activity
BKP57_19760	COG4840	Belongs to the UPF0435 family
BKP57_19765	COG1196	nuclear chromosome segregation
BKP57_19770	COG0552	protein localization to endoplasmic reticulum
BKP57_19775	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BKP57_19780	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BKP57_19785	COG0228	four-way junction DNA binding
BKP57_19790	COG1837	Belongs to the UPF0109 family
BKP57_19800	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BKP57_19805	COG0336	Belongs to the RNA methyltransferase TrmD family
BKP57_19810	COG0335	large ribosomal subunit rRNA binding
BKP57_19820	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BKP57_19825	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BKP57_19835	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BKP57_19840	COG0045	succinate-CoA ligase (ADP-forming) activity
BKP57_19845	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BKP57_19850	COG0758	DNA mediated transformation
BKP57_19855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BKP57_19860	COG4974	Belongs to the 'phage' integrase family
BKP57_19865	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BKP57_19870	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BKP57_19875	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BKP57_19880	COG1815	bacterial-type flagellum-dependent cell motility
BKP57_19885	COG1558	bacterial-type flagellum-dependent cell motility
BKP57_19890	COG1677	Flagellar hook-basal body complex protein FliE
BKP57_19895	COG1766	The M ring may be actively involved in energy transduction
BKP57_19900	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKP57_19910	COG1157	protein secretion by the type III secretion system
BKP57_19925	COG3144	bacterial-type flagellum assembly
BKP57_19930	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BKP57_19935	COG4786	Flagellar basal body rod
BKP57_19940	COG1582	Flagellar protein (FlbD)
BKP57_19945	COG1580	Controls the rotational direction of flagella during chemotaxis
BKP57_19950	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKP57_19955	COG1776	CheC inhibitor of MCP methylation
BKP57_19955	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BKP57_19960	COG2201	protein-glutamate methylesterase activity
BKP57_19965	COG3190	flagellar
BKP57_19970	COG1338	Plays a role in the flagellum-specific transport system
BKP57_19975	COG1987	bacterial-type flagellum assembly
BKP57_19980	COG1684	flagellar biosynthetic protein fliR
BKP57_19985	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BKP57_19990	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BKP57_19995	COG1419	protein localization to endoplasmic reticulum
BKP57_20000	COG0455	bacterial-type flagellum organization
BKP57_20005	COG2201	protein-glutamate methylesterase activity
BKP57_20010	COG2198	Histidine kinase
BKP57_20010	COG0643	Histidine kinase
BKP57_20015	COG0835	chemotaxis
BKP57_20020	COG1776	CheC inhibitor of MCP methylation
BKP57_20025	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BKP57_20030	COG1191	sigma factor activity
BKP57_20050	COG0052	Belongs to the universal ribosomal protein uS2 family
BKP57_20055	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BKP57_20060	COG0528	UMP kinase activity
BKP57_20065	COG0233	cytoplasmic translational termination
BKP57_20070	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BKP57_20075	COG4589	Belongs to the CDS family
BKP57_20080	COG0750	zinc metalloprotease
BKP57_20085	COG2176	DNA-directed DNA polymerase activity
BKP57_20090	COG0779	Required for maturation of 30S ribosomal subunits
BKP57_20095	COG0195	Participates in both transcription termination and antitermination
BKP57_20100	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BKP57_20110	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BKP57_20115	COG1550	Protein conserved in bacteria
BKP57_20120	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BKP57_20125	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BKP57_20130	COG0196	riboflavin kinase activity
BKP57_20135	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BKP57_20140	COG1185	polyribonucleotide nucleotidyltransferase activity
BKP57_20145	COG0726	polysaccharide deacetylase
BKP57_20150	COG0612	Peptidase, M16
BKP57_20155	COG1873	PFAM PRC-barrel domain
BKP57_20160	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BKP57_20165	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BKP57_20170	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BKP57_20175	COG0527	aspartate kinase activity
BKP57_20180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BKP57_20185	COG0740	serine-type endopeptidase activity
BKP57_20195	COG1674	ftsk spoiiie
BKP57_20200	COG2188	Transcriptional regulator
BKP57_20225	COG0612	Peptidase, M16
BKP57_20230	COG0612	Peptidase, M16
BKP57_20235	COG0300	oxidoreductase activity
BKP57_20250	COG1426	Protein conserved in bacteria
BKP57_20255	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BKP57_20260	COG1058	Belongs to the CinA family
BKP57_20260	COG1546	Belongs to the CinA family
BKP57_20265	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BKP57_20275	COG1418	mRNA catabolic process
BKP57_20280	COG1692	metallophosphoesterase
BKP57_20285	COG2359	stage V sporulation protein S
BKP57_20290	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BKP57_20295	COG4550	Control of competence regulator ComK, YlbF/YmcA
BKP57_20305	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BKP57_20310	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BKP57_20315	COG0783	Belongs to the Dps family
BKP57_20320	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BKP57_20325	COG1923	regulation of RNA biosynthetic process
BKP57_20330	COG0464	growth
BKP57_20335	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BKP57_20340	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BKP57_20365	COG0789	Transcriptional regulator
BKP57_20370	COG0174	glutamine synthetase
BKP57_20380	COG3152	Membrane
BKP57_20455	COG5377	YqaJ viral recombinase family
BKP57_20535	COG4824	toxin secretion phage lysis holin
BKP57_20540	COG0860	N-Acetylmuramoyl-L-alanine amidase
BKP57_20580	COG3546	catalase activity
BKP57_20615	COG3546	catalase activity
BKP57_20620	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BKP57_20625	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BKP57_20630	COG4224	UPF0291 protein
BKP57_20645	COG3763	UPF0154 protein
BKP57_20650	COG0785	Cytochrome C biogenesis protein
BKP57_20655	COG2111	Na H antiporter
BKP57_20660	COG2201	protein-glutamate methylesterase activity
BKP57_20665	COG4846	Membrane protein involved in cytochrome C biogenesis
BKP57_20680	COG4191	Histidine kinase
BKP57_20685	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BKP57_20690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BKP57_20700	COG0824	Thioesterase
BKP57_20715	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BKP57_20720	COG1469	GTP cyclohydrolase I activity
BKP57_20725	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BKP57_20740	COG1832	CoA-binding protein
BKP57_20745	COG0187	DNA topoisomerase II activity
BKP57_20750	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BKP57_20760	COG1960	acyl-CoA dehydrogenase activity
BKP57_20765	COG0318	PFAM AMP-dependent synthetase and ligase
BKP57_20770	COG0439	Biotin carboxylase
BKP57_20775	COG0511	ligase activity, forming carbon-carbon bonds
BKP57_20780	COG1024	Enoyl-CoA hydratase
BKP57_20785	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BKP57_20790	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BKP57_20795	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BKP57_20800	COG1126	abc transporter atp-binding protein
BKP57_20805	COG0390	transport system, permease component
BKP57_20815	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BKP57_20845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BKP57_20850	COG0789	Transcriptional regulator
BKP57_20865	COG0346	lactoylglutathione lyase activity
BKP57_20910	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BKP57_20915	COG0210	DNA helicase
BKP57_20950	COG4974	Belongs to the 'phage' integrase family
BKP57_20955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BKP57_20955	COG0723	plastoquinol--plastocyanin reductase activity
BKP57_20960	COG1254	Belongs to the acylphosphatase family
BKP57_20990	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKP57_20990	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BKP57_21010	COG4479	Belongs to the UPF0346 family
BKP57_21015	COG0805	protein transport
BKP57_21020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BKP57_21030	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BKP57_21035	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BKP57_21040	COG0791	NLP P60 protein
BKP57_21040	COG1388	LysM domain
BKP57_21050	COG1418	mRNA catabolic process
BKP57_21065	COG0659	secondary active sulfate transmembrane transporter activity
BKP57_21070	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BKP57_21075	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BKP57_21080	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BKP57_21085	COG1755	Isoprenylcysteine carboxyl methyltransferase
BKP57_21090	COG3424	synthase
BKP57_21095	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BKP57_21100	COG0116	Belongs to the methyltransferase superfamily