locus-tag	class	description
X953_00005	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
X953_00010	ENOG410848D	S4 domain protein YaaA
X953_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
X953_00025	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
X953_00030	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
X953_00035	ENOG4105DHT	Metal Dependent Phosphohydrolase
X953_00050	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
X953_00060	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
X953_00065	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
X953_00070	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
X953_00080	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
X953_00085	ENOG4108UMI	ABC transporter, permease
X953_00115	ENOG4105II7	pyrroline-5-carboxylate reductase
X953_00120	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
X953_00125	ENOG4105ZMH	deoxynucleoside kinase
X953_00155	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
X953_00160	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
X953_00165	ENOG4105KPV	Transcriptional regulator
X953_00170	ENOG4107RKG	DJ-1/PfpI family
X953_00175	ENOG4105VRS	hydrolase family 18
X953_00180	ENOG4105GTG	Isochorismatase
X953_00185	ENOG4108Z6B	deaminase
X953_00195	ENOG4105C6E	dna polymerase iii
X953_00200	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
X953_00205	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
X953_00225	ENOG4105CXN	decarboxylase
X953_00230	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
X953_00235	ENOG4105X0R	protein from nitrogen regulatory protein P-II
X953_00240	ENOG4105XVJ	Protein of unknown function (DUF327)
X953_00245	ENOG4105FA2	dna polymerase iii
X953_00250	ENOG4105MA4	psp1 domain protein
X953_00255	ENOG4105QD5	Involved in initiation control of chromosome replication (By similarity)
X953_00260	ENOG41060K3	Methyltransferase
X953_00265	ENOG4105VC4	domain protein
X953_00270	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
X953_00280	ENOG4105KRN	Transcriptional regulator, abrb family
X953_00290	ENOG4105F8V	Hydrolase, tatD family
X953_00295	ENOG41069ER	domain protein
X953_00305	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
X953_00310	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
X953_00315	ENOG4105XFA	sporulation peptidase YabG
X953_00320	ENOG4105W42	Veg protein
X953_00330	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
X953_00335	ENOG4105DFT	pur operon repressor
X953_00340	ENOG4105K4W	Could be involved in septation (By similarity)
X953_00345	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
X953_00350	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
X953_00355	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
X953_00360	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
X953_00370	ENOG4108JA2	transcriptioN-repair coupling factor
X953_00375	ENOG4108M14	stage v sporulation protein t
X953_00385	ENOG4108IY2	MazG family
X953_00390	ENOG41082I2	s4 domain protein
X953_00400	ENOG4105VYY	sporulation protein yabp
X953_00415	ENOG41060GV	RNA binding s1 domain protein
X953_00440	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
X953_00445	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
X953_00450	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
X953_00460	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
X953_00465	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
X953_00470	ENOG4107U48	ppic-type peptidyL-prolyl cis-trans isomerase
X953_00480	ENOG4105C6T	cysteine synthase
X953_00490	ENOG4105EEI	dihydropteroate synthase
X953_00495	ENOG4105KRF	dihydroneopterin aldolase
X953_00500	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
X953_00510	ENOG4105CRK	lysyL-tRNA synthetase
X953_00530	ENOG4105KT7	mgtC SapB transporter
X953_00540	ENOG4108Z0C	Uvrb UvrC protein
X953_00545	ENOG41066A3	ATP guanido phosphotransferase
X953_00550	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
X953_00560	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
X953_00565	ENOG4105CTP	PilT protein domain protein
X953_00570	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
X953_00575	ENOG4105D7W	serine acetyltransferase
X953_00580	ENOG4105C8N	cysteinyl-tRNA synthetase
X953_00590	ENOG4105C2N	RNA methyltransferase TrmH family group 3
X953_00595	ENOG4105M0M	Tetracycline resistance protein
X953_00600	ENOG4105QIV	RNA polymerase
X953_00610	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
X953_00615	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
X953_00620	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
X953_00625	ENOG4108VZM	50s ribosomal protein L10
X953_00630	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
X953_00635	ENOG4107Y49	methyltransferase
X953_00640	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
X953_00645	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
X953_00650	ENOG4105XPM	ribosomal protein
X953_00655	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
X953_00660	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
X953_00665	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
X953_00670	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
X953_00675	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
X953_00680	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
X953_00685	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
X953_00690	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
X953_00695	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
X953_00700	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
X953_00705	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
X953_00710	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
X953_00715	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
X953_00720	ENOG41082SA	50s ribosomal protein l29
X953_00725	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
X953_00730	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
X953_00735	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
X953_00740	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
X953_00745	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
X953_00750	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
X953_00755	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
X953_00760	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
X953_00765	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
X953_00770	ENOG4105VPB	50S ribosomal protein L30
X953_00775	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
X953_00780	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
X953_00785	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
X953_00795	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
X953_00800	ENOG41067V7	50S ribosomal protein L36
X953_00805	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
X953_00810	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
X953_00815	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
X953_00820	ENOG4108ZT0	50S ribosomal protein l17
X953_00830	ENOG4108JJB	ABC transporter
X953_00835	ENOG4108JJB	ABC transporter
X953_00840	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
X953_00845	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
X953_00850	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
X953_00855	ENOG4108UJD	30S ribosomal protein S9
X953_00965	ENOG41067MG	lrgb family
X953_00975	ENOG4105CMU	LysR family (Transcriptional regulator
X953_00980	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
X953_01020	ENOG4105EYF	MMPL domain protein
X953_01025	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
X953_01030	ENOG4107T89	von Willebrand factor, type A
X953_01055	ENOG4107U9T	Pfam:Ribonuclease_BN
X953_01085	ENOG4105D1F	ATP-binding protein
X953_01100	ENOG4108NMV	polysaccharide deacetylase
X953_01155	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
X953_01165	ENOG4105NAE	bifunctional deaminase-reductase domain protein
X953_01250	ENOG4105EMN	RNA polymerase sigma factor
X953_01255	ENOG4105KXB	anti-sigma factor
X953_01260	ENOG4105C8B	TIGR00159 family
X953_01265	ENOG4107U5W	ybbr family
X953_01270	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
X953_01275	ENOG4105EFI	regulatoR
X953_01280	ENOG4105BZU	Histidine kinase
X953_01285	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
X953_01315	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
X953_01355	ENOG4105C8Q	Methyl-accepting chemotaxis
X953_01360	ENOG4105BZU	Histidine kinase
X953_01365	ENOG4107SDU	Methyl-accepting chemotaxis
X953_01370	ENOG4105BZU	Histidine kinase
X953_01460	ENOG4105CVR	type I restriction-modification system
X953_01550	ENOG4105F8V	Hydrolase, tatD family
X953_01655	ENOG4105BZU	Histidine kinase
X953_01740	ENOG4108FPN	Integrase
X953_01745	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
X953_01750	ENOG4105ZX1	Transposase C
X953_01770	ENOG4105H3G	oxidoreductase
X953_01810	ENOG4107QTH	restriction modification system DNA specificity domain
X953_01910	ENOG4108A04	Beta-lactamase
X953_01915	ENOG4105I3N	Conserved Protein
X953_01925	ENOG4105C5H	ABC transporter
X953_01930	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
X953_01945	ENOG4105BZU	Histidine kinase
X953_01965	ENOG4108JJ9	ABC, transporter
X953_01970	ENOG4108JJ8	(ABC) transporter
X953_01985	ENOG4105CIG	ABC transporter
X953_02010	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
X953_02050	ENOG4105WH1	Two component transcriptional regulator luxr family
X953_02060	ENOG4105BZU	Histidine kinase
X953_02070	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
X953_02080	ENOG4105DRR	Transcriptional regulator, GntR family
X953_02085	ENOG4105CH6	catalase
X953_02095	ENOG4105D64	Mechanosensitive ion channel
X953_02125	ENOG4108S4H	thioesterase Superfamily protein
X953_02140	ENOG4105DR4	Methyltransferase
X953_02145	ENOG4105DBV	ornithine carbamoyltransferase
X953_02155	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
X953_02160	ENOG4105D6E	homoserine dehydrogenase
X953_02180	ENOG4108SUT	Major Facilitator Superfamily
X953_02225	ENOG4105HMI	Membrane
X953_02235	ENOG4107TXC	Transcriptional regulator
X953_02240	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
X953_02245	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
X953_02260	ENOG4105E2A	Dehydrogenase
X953_02280	ENOG4108IA2	Sodium pantothenate symporter
X953_02290	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
X953_02300	ENOG4105C94	Transporter
X953_02320	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
X953_02345	ENOG4105CGK	Exodeoxyribonuclease III
X953_02350	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
X953_02355	ENOG4105CJ1	ABC, transporter
X953_02370	ENOG4105XXY	Thioredoxin
X953_02390	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
X953_02395	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
X953_02405	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
X953_02410	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
X953_02415	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
X953_02420	ENOG4105DK0	Indole-3-glycerol phosphate synthase
X953_02425	ENOG4108I0Q	anthranilate phosphoribosyltransferase
X953_02430	ENOG4105DDQ	anthranilate synthase
X953_02435	ENOG4105CRQ	synthase (Component I)
X953_02445	ENOG4105CPF	Cell wall formation (By similarity)
X953_02450	ENOG4105BZG	amino acid carrier protein
X953_02455	ENOG4107Y03	Nitroreductase
X953_02480	ENOG4108VXD	carboxy-peptidase
X953_02485	ENOG4105D94	Major Facilitator Superfamily
X953_02490	ENOG4108J59	Extracellular solute-binding protein, family 5
X953_02495	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
X953_02505	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
X953_02510	ENOG4105KHC	sulfurtransferase
X953_02515	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
X953_02520	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
X953_02530	ENOG4105C8Q	Methyl-accepting chemotaxis
X953_02540	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
X953_02560	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
X953_02565	ENOG4105NRR	Uncharacterized protein conserved in bacteria (DUF2188)
X953_02575	ENOG4107ZXU	DSBA oxidoreductase
X953_02580	ENOG4105DHS	permease protein
X953_02585	ENOG4105CM4	permease protein
X953_02590	ENOG4108IPW	abc transporter atp-binding protein
X953_02600	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
X953_02605	ENOG4105CIH	Imidazole acetol-phosphate transaminase
X953_02610	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
X953_02615	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
X953_02620	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
X953_02625	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
X953_02630	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
X953_02635	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
X953_02640	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
X953_02645	ENOG4108IQ6	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
X953_02650	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
X953_02655	ENOG4105WD1	Membrane
X953_02665	ENOG4105D4A	Cell wall formation (By similarity)
X953_02680	ENOG4105E5Q	amino acid AbC transporter
X953_02690	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
X953_02700	ENOG4105EE0	oxidoreductase
X953_02710	ENOG4108Y1J	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
X953_02715	ENOG4105SXS	Protein of unknown function (DUF456)
X953_02720	ENOG4105DWF	phosphomethylpyrimidine kinase
X953_02735	ENOG4107R1M	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
X953_02745	ENOG4108HW3	(ABC) transporter
X953_02750	ENOG4105E5Q	amino acid AbC transporter
X953_02755	ENOG4105CDA	abc transporter atp-binding protein
X953_02760	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
X953_02765	ENOG4108V06	Glutathione peroxidase
X953_02770	ENOG4108K88	Membrane
X953_02780	ENOG4105DCF	alanine dehydrogenase
X953_02785	ENOG4105C72	UPF0176 protein
X953_02805	ENOG4105VEQ	Cold shock protein
X953_02815	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
X953_02825	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
X953_02840	ENOG4105VES	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
X953_02845	ENOG4105C0H	protease
X953_02855	ENOG41062D9	Histidine kinase
X953_02860	ENOG4105CI3	gtp-binding protein typa
X953_02865	ENOG4107TUM	Amidinotransferase
X953_02875	ENOG4108TU7	Inherit from COG: (ABC) transporter
X953_02880	ENOG4105CJ1	ABC, transporter
X953_02890	ENOG4105CHU	acetyl-coa acetyltransferase
X953_02910	ENOG4105SZ6	Thioredoxin
X953_02920	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
X953_02925	ENOG41062D9	Histidine kinase
X953_02935	ENOG4109050	May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG)
X953_02945	ENOG41090MY	MarR family Transcriptional regulator
X953_02980	ENOG4105C1J	atp-dependent rna helicase
X953_02990	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
X953_02995	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
X953_03000	ENOG4108SGW	outer membrane lipoprotein-sorting protein-like protein
X953_03005	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
X953_03015	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
X953_03025	ENOG4105FUA	antagonist
X953_03030	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
X953_03035	ENOG4107SGM	protein serine threonine phosphatase
X953_03040	ENOG4105WN5	stage II sporulation protein
X953_03045	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
X953_03055	ENOG41064BQ	Phosphatase
X953_03065	ENOG4105CH6	catalase
X953_03070	ENOG410906U	SprT-like
X953_03160	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
X953_03165	ENOG4105K8N	protein family UPF0079, ATPase
X953_03170	ENOG41072GX	Peptidase M22 Glycoprotease
X953_03175	ENOG410801F	ribosomal-protein-alanine acetyltransferase
X953_03180	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
X953_03190	ENOG4105C5H	ABC transporter
X953_03200	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
X953_03210	ENOG4108TYN	CAAX amino terminal protease family protein
X953_03215	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
X953_03220	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
X953_03225	ENOG4105VTR	Integrase
X953_03285	ENOG4105E5H	Transposase
X953_03300	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
X953_03315	ENOG4107RRE	RNA-directed DNA polymerase
X953_03335	ENOG41090E6	transcriptional regulator MERR family
X953_03345	ENOG4108RZE	Tetr family transcriptional regulator
X953_03350	ENOG4105C94	Transporter
X953_03355	ENOG4105C4B	ABC transporter, permease
X953_03360	ENOG4108IXI	(ABC) transporter
X953_03390	ENOG4105D8X	mechanosensitive ion channel
X953_03405	ENOG4108NHD	germination protein
X953_03420	ENOG4105CFC	Transporter
X953_03445	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
X953_03460	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
X953_03470	ENOG4105C7N	Xanthine uracil vitamin C permease
X953_03480	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
X953_03485	ENOG4108RPX	mosc domain containing protein
X953_03495	ENOG4108U5N	UPF0316 protein
X953_03500	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
X953_03505	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
X953_03510	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
X953_03515	ENOG4105C83	adenylosuccinate lyase
X953_03520	ENOG4105C8V	SAICAR synthetase
X953_03525	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
X953_03530	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
X953_03535	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
X953_03545	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
X953_03550	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
X953_03555	ENOG4105DC1	bifunctional purine biosynthesis protein purh
X953_03560	ENOG4105C12	Phosphoribosylglycinamide synthetase
X953_03565	ENOG4105CPN	adenine deaminase
X953_03570	ENOG4108R5T	secreted protein
X953_03575	ENOG4105KGF	protein, YerC YecD
X953_03580	ENOG4108RE7	deoxyribonuclease
X953_03590	ENOG4108RTE	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity)
X953_03595	ENOG4105C4R	Atp-dependent dna helicase
X953_03600	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
X953_03610	ENOG4105C26	Dehydrogenase
X953_03625	ENOG4105CK7	Sodium proline symporter
X953_03630	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
X953_03635	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
X953_03640	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
X953_03645	ENOG4105CBD	Diacylglycerol kinase
X953_03650	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
X953_03680	ENOG41060D1	Quinol oxidase
X953_03690	ENOG4105BZ9	Cytochrome C oxidase, subunit I
X953_03700	ENOG4105BZ4	penicillin-binding protein
X953_03705	ENOG4105VEQ	Cold shock protein
X953_03710	ENOG4105D5G	Transposase
X953_03715	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
X953_03740	ENOG4108RCM	Nitroreductase
X953_03745	ENOG4108YBP	pseudouridine synthase
X953_03760	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
X953_03770	ENOG4105C5H	ABC transporter
X953_03795	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
X953_03800	ENOG4105C8J	)-transporter
X953_03805	ENOG4107S6Z	Na H antiporter
X953_03810	ENOG4105CHM	Aminotransferase
X953_03815	ENOG4105C7K	acetolactate synthase
X953_03820	ENOG4105C26	Dehydrogenase
X953_03830	ENOG4107258	Transcriptional regulator
X953_03840	ENOG4105C26	Dehydrogenase
X953_03850	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
X953_03860	ENOG4105K4I	Scp-like extracellular
X953_03865	ENOG4105CSV	Glutaminase
X953_03870	ENOG4108RAV	Conserved protein
X953_03875	ENOG4105BZG	amino acid carrier protein
X953_03885	ENOG4107U9T	Pfam:Ribonuclease_BN
X953_03890	ENOG4105C59	p-type ATPase
X953_03895	ENOG4108ISG	Major Facilitator
X953_03925	ENOG4105BZU	Histidine kinase
X953_03935	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
X953_03945	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
X953_03950	ENOG41073TP	transcriptional regulator
X953_03955	ENOG4105DVE	abc transporter atp-binding protein
X953_03970	ENOG4105DA5	(ABC) transporter
X953_03985	ENOG4105FDP	GntR family transcriptional regulator
X953_04010	ENOG4105ECP	epimerase
X953_04015	ENOG410902V	Modulates RecA activity (By similarity)
X953_04030	ENOG41067AE	Membrane-bound metal-dependent hydrolase
X953_04050	ENOG4105EVI	UPF0374 protein
X953_04055	ENOG4105BZ1	(ABC) transporter
X953_04060	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
X953_04070	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
X953_04075	ENOG4105D3Q	Sugar transferase
X953_04080	ENOG4105C5I	Dehydrogenase
X953_04085	ENOG4105G5W	regulator Fur family
X953_04090	ENOG4105CRQ	synthase (Component I)
X953_04095	ENOG4105DDQ	anthranilate synthase
X953_04100	ENOG4105TUA	UPF0295 protein
X953_04220	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
X953_04230	ENOG4105EYF	MMPL domain protein
X953_04245	ENOG4108Z03	MAF-like protein
X953_04255	ENOG4105KVH	Transcriptional regulator
X953_04265	ENOG4107V0Z	fmn reductase
X953_04285	ENOG4107VFR	oxidoreductase
X953_04295	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
X953_04305	ENOG410742N	Small acid-soluble spore protein P family
X953_04315	ENOG4108UKS	UPF0398 protein
X953_04345	ENOG4108W0I	acetyltransferase
X953_04370	ENOG4107SVH	Potassium channel protein
X953_04380	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
X953_04570	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
X953_04575	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
X953_04580	ENOG4108Z7R	Chaperone CsaA
X953_04590	ENOG41068KF	Universal stress protein
X953_04595	ENOG4108J59	Extracellular solute-binding protein, family 5
X953_04600	ENOG4105CQB	FAD linked oxidase domain protein
X953_04610	ENOG4105CM2	brancheD-chain amino acid aminotransferase
X953_04620	ENOG4108JQ1	Dehydrogenase
X953_04640	ENOG41085PJ	rdd domain containing protein
X953_04645	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
X953_04650	ENOG4105D07	Signal peptide peptidase, SppA
X953_04655	ENOG4105VK3	rdd domain containing protein
X953_04660	ENOG4105CEY	Amp-dependent synthetase and ligase
X953_04670	ENOG4106DDH	Sporulation-specific SASP protein
X953_04690	ENOG4105C2W	permease
X953_04715	ENOG4105CIS	alcohol dehydrogenase
X953_04730	ENOG4107P5I	polyketide synthase
X953_04755	ENOG4106DF1	
X953_04765	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
X953_04770	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
X953_04775	ENOG4105CAS	nag kinase
X953_04780	ENOG4105C8Y	Acetylornithine aminotransferase
X953_04785	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
X953_04790	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
X953_04805	ENOG4107RU9	Transcriptional regulator, Crp Fnr family
X953_04820	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
X953_04825	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
X953_04835	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
X953_04850	ENOG4105C7S	Dehydrogenase
X953_04855	ENOG4105D9N	nucleoside
X953_04865	ENOG4107QMU	Mate efflux family protein
X953_04870	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
X953_04880	ENOG4108B31	Spore germination protein
X953_04890	ENOG4108V2W	Carbonate dehydratase
X953_04900	ENOG4105BZ1	(ABC) transporter
X953_04905	ENOG4105BZ1	(ABC) transporter
X953_04910	ENOG4105C0H	protease
X953_04925	ENOG4108WZW	RNA polymerase sigma
X953_04950	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
X953_04960	ENOG4105C28	cystathionine
X953_04965	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
X953_04970	ENOG410904N	short-chain dehydrogenase reductase
X953_04990	ENOG4105CJ1	ABC, transporter
X953_04995	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
X953_05005	ENOG4105DFD	Na H antiporter
X953_05010	ENOG4108UMN	azlc family
X953_05030	ENOG4105DEU	major facilitator superfamily
X953_05040	ENOG4105C9Q	fumarate hydratase class II
X953_05060	ENOG4105WZB	UPF0342 protein
X953_05065	ENOG4105CGU	Enoyl-CoA hydratase
X953_05075	ENOG4108IUX	(ABC) transporter
X953_05080	ENOG4105RHA	ABC transporter, permease
X953_05090	ENOG4107VRP	DNA repair exonuclease
X953_05095	ENOG4106D4I	domain protein
X953_05100	ENOG4105TRT	Transcriptional regulator
X953_05105	ENOG4105EQI	Metal Dependent Phosphohydrolase
X953_05115	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
X953_05135	ENOG4107HG4	Transcriptional regulator
X953_05140	ENOG4108IJ7	Glycine betaine
X953_05165	ENOG4105NBU	tryptophan transport protein
X953_05170	ENOG4105K59	histidine triad (HIT) protein
X953_05190	ENOG4108UQY	Iron-storage protein
X953_05200	ENOG4107Y80	Major Facilitator superfamily
X953_05210	ENOG4105ENE	Histidine kinase
X953_05215	ENOG4105WH1	Two component transcriptional regulator luxr family
X953_05225	ENOG4105Q24	Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation
X953_05230	ENOG4105BZ4	penicillin-binding protein
X953_05235	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
X953_05240	ENOG4107TTW	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
X953_05245	ENOG4105C1Q	protoporphyrinogen oxidase
X953_05250	ENOG4105DPN	Oligoendopeptidase f
X953_05255	ENOG4106AXD	
X953_05260	ENOG4108RQ5	Beta-lactamase domain-containing protein
X953_05265	ENOG4105DF9	Lipoate-protein, ligase
X953_05270	ENOG4105CEY	Amp-dependent synthetase and ligase
X953_05295	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
X953_05300	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
X953_05310	ENOG4105NAA	Cytochrome C oxidase, subunit II
X953_05315	ENOG4107RQ2	Cytochrome c oxidase, subunit I
X953_05365	ENOG4105C8Y	Acetylornithine aminotransferase
X953_05375	ENOG4105D7V	transposase
X953_05385	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
X953_05395	ENOG4105EPR	degv family
X953_05400	ENOG4107AYK	membrAne
X953_05425	ENOG4108KP7	hydrolase
X953_05430	ENOG4108MXZ	Esterase
X953_05435	ENOG4105VG1	fes assembly suf system protein
X953_05445	ENOG4108ZAF	Molybdopterin
X953_05455	ENOG4105IJJ	transcriptional regulator, crp fnr family
X953_05470	ENOG4107V6Q	Cyclic nucleotide-binding domain
X953_05475	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
X953_05495	ENOG4107RMD	Basic membrane lipoprotein
X953_05500	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
X953_05505	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
X953_05515	ENOG4108KU1	UPF0736 protein
X953_05520	ENOG4105C31	Tryptophanyl-tRNA synthetase
X953_05530	ENOG4105ETU	transcriptional activator (TenA
X953_05545	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
X953_05555	ENOG41090UD	(LipO)protein
X953_05570	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
X953_05575	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
X953_05585	ENOG4105DPN	Oligoendopeptidase f
X953_05590	ENOG4105T58	Dithiol-disulfide isomerase
X953_05595	ENOG4108Z18	K06886 hemoglobin
X953_05600	ENOG4105MIX	Adenylate cyclase
X953_05610	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
X953_05615	ENOG4105EMS	pseudouridine synthase
X953_05620	ENOG4107S1Q	Phosphatase
X953_05625	ENOG4105CJW	magnesium transporter
X953_05655	ENOG4105H67	Protein of unknown function (DUF421)
X953_05665	ENOG4108ZMI	UPF0477 protein
X953_05675	ENOG4105BZ1	(ABC) transporter
X953_05680	ENOG4105BZ1	(ABC) transporter
X953_05695	ENOG4105CH6	catalase
X953_05700	ENOG4105DSE	periplasmic solute binding protein
X953_05755	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
X953_05790	ENOG4106FGC	
X953_05800	ENOG4105UYK	outer membrane protein a
X953_05810	ENOG4105QVS	general stress protein
X953_05815	ENOG4105C5H	ABC transporter
X953_05830	ENOG4105D5G	Transposase
X953_05835	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
X953_05860	ENOG4107SCK	Monooxygenase
X953_05875	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
X953_05880	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
X953_05890	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
X953_05895	ENOG4105E1K	spore germination protein
X953_05900	ENOG4108B31	Spore germination protein
X953_05940	ENOG4105DWT	malate dehydrogenase (quinone)
X953_06055	ENOG4107T5V	SNARE associated Golgi
X953_06065	ENOG4105HHM	rdd domain containing protein
X953_06080	ENOG4105KNA	-acetyltransferase
X953_06115	ENOG4107Y9E	nuclease
X953_06125	ENOG4108VK3	Cupin 2 Conserved Barrel Domain Protein
X953_06135	ENOG4105RHY	Pfam:UPF0157
X953_06175	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
X953_06180	ENOG4105EHG	Permease protein
X953_06185	ENOG4105E0A	ABC, transporter
X953_06190	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
X953_06195	ENOG4105CIH	Imidazole acetol-phosphate transaminase
X953_06205	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
X953_06210	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
X953_06215	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
X953_06225	ENOG4108WBT	adenosyltransferase
X953_06260	ENOG4105DTQ	mandelate racemase muconate lactonizing
X953_06275	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
X953_06285	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
X953_06335	ENOG4105K59	histidine triad (HIT) protein
X953_06370	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
X953_06500	ENOG4105VRR	gCN5-related N-acetyltransferase
X953_06565	ENOG4105CIG	ABC transporter
X953_06590	ENOG4105RHY	Pfam:UPF0157
X953_06620	ENOG4107RA9	decarboxylase
X953_06640	ENOG4105HRU	Glyoxalase Bleomycin resistance protein (Dioxygenase
X953_06650	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
X953_06710	ENOG4105IIP	Membrane
X953_06720	ENOG4108I0C	methyltransferase
X953_06765	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
X953_06770	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
X953_06775	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
X953_06810	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
X953_06910	ENOG4105DJ2	Major Facilitator Superfamily
X953_06915	ENOG4107EJG	GntR family transcriptional regulator
X953_06930	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
X953_06970	ENOG4108YYC	ycei family
X953_06980	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
X953_06990	ENOG41090MY	MarR family Transcriptional regulator
X953_06995	ENOG4108ZJ4	polysaccharide deacetylase
X953_07000	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
X953_07065	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
X953_07070	ENOG4105CMT	Dihydroxyacetone kinase
X953_07075	ENOG4108UTZ	Dihydroxyacetone kinase
X953_07080	ENOG4105VDH	Dihydroxyacetone kinase
X953_07120	ENOG4105DY9	regulatoR
X953_07125	ENOG4105K7K	Transcriptional regulator
X953_07150	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
X953_07155	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
X953_07170	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
X953_07200	ENOG4107WCA	isomerase
X953_07220	ENOG4105CRW	Short chain fatty acid transporter
X953_07240	ENOG4105M6F	mutator MutT protein
X953_07245	ENOG4105CFI	type iii restriction protein res subunit
X953_07250	ENOG4105CFI	type iii restriction protein res subunit
X953_07285	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
X953_07300	ENOG4105GIG	
X953_07400	ENOG4105VMP	Transcriptional regulator
X953_07405	ENOG4105NX3	Membrane
X953_07425	ENOG4105CVJ	phosphoglycerate mutase
X953_07430	ENOG4105KCT	ABC transporter
X953_07435	ENOG4108M15	ABC transporter
X953_07450	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
X953_07455	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
X953_07480	ENOG4105WYW	fructose-bisphosphate aldolase
X953_07500	ENOG4105DEN	Luciferase family
X953_07510	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
X953_07515	ENOG4107SDU	Methyl-accepting chemotaxis
X953_07520	ENOG4105VEM	Conserved domain protein
X953_07565	ENOG41060GV	RNA binding s1 domain protein
X953_07575	ENOG4105C26	Dehydrogenase
X953_07585	ENOG4105C26	Dehydrogenase
X953_07595	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
X953_07600	ENOG4106IPI	cyclase, family
X953_07610	ENOG4105C8J	)-transporter
X953_07615	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
X953_07655	ENOG4105FQP	Beta-lactamase
X953_07660	ENOG4105RHY	Pfam:UPF0157
X953_07680	ENOG4105CPC	Aldo Keto reductase
X953_07685	ENOG4105D5G	Transposase
X953_07695	ENOG4108SJC	Membrane
X953_07700	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
X953_07745	ENOG4105C94	Transporter
X953_07750	ENOG41067SE	Tetr family transcriptional regulator
X953_07755	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
X953_07780	ENOG4105E4C	Lytic transglycosylase catalytic
X953_07785	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
X953_07790	ENOG4105FGV	Chromate
X953_07795	ENOG4105CAH	Chromate
X953_07805	ENOG41082JN	Transcriptional regulator
X953_07840	ENOG4105EHG	Permease protein
X953_07860	ENOG4105E2A	Dehydrogenase
X953_07865	ENOG4108IYC	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
X953_07905	ENOG4107STF	Involved in phosphonate degradation (By similarity)
X953_07910	ENOG4105E0M	Sulfatase
X953_07915	ENOG41082YX	Transcriptional regulator, arsr family
X953_07920	ENOG4107R5R	arsenical pump membrane protein
X953_07925	ENOG4108UXE	Protein tyrosine phosphatase
X953_07930	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
X953_07940	ENOG4105D7N	magnesium and cobalt transport protein CorA
X953_07950	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
X953_07955	ENOG4108R6K	riboflavin synthase, subunit alpha
X953_07960	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
X953_07965	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
X953_07985	ENOG4107ZQN	disulfide bond
X953_08015	ENOG4105BZU	Histidine kinase
X953_08020	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
X953_08030	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
X953_08040	ENOG41068WN	
X953_08050	ENOG4105F6S	Spore photoproduct lyase
X953_08065	ENOG4105MRC	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth
X953_08095	ENOG4107ETC	gas vesicle protein
X953_08105	ENOG4105W2E	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth (By similarity)
X953_08135	ENOG4105VT3	DNA binding domain protein, excisionase family
X953_08140	ENOG4105CHH	sulfate transporter
X953_08165	ENOG4105Q24	Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation
X953_08180	ENOG4105BZU	Histidine kinase
X953_08200	ENOG4105YB8	TM2 domain containing protein
X953_08205	ENOG4105DJZ	UPF0182 protein
X953_08240	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
X953_08245	ENOG4105DUX	Transporter
X953_08280	ENOG41080XP	Cbs domain
X953_08315	ENOG4105CBX	hi0933 family
X953_08340	ENOG4108V15	phosphotransferase enzyme family
X953_08350	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
X953_08355	ENOG4105C8F	Beta-lactamase domain protein
X953_08370	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
X953_08375	ENOG4105D7V	transposase
X953_08380	ENOG4108V0E	nucleoside 2-deoxyribosyltransferase YtoQ
X953_08390	ENOG4108NKM	UPF0354 protein
X953_08395	ENOG4108VDD	TRNA binding domain protein
X953_08410	ENOG4105DFU	Cell wall formation (By similarity)
X953_08425	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
X953_08430	ENOG4105ETE	Transcriptional regulator (LacI family
X953_08435	ENOG4105E14	MotA TolQ exbB proton channel
X953_08440	ENOG4106VK6	Flagellar motor protein
X953_08445	ENOG4105DGU	Histone deacetylase
X953_08450	ENOG4105W87	Cbs domain
X953_08455	ENOG4105F1V	Acetoin utilization protein
X953_08460	ENOG4105BZ4	penicillin-binding protein
X953_08465	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
X953_08470	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
X953_08475	ENOG4105BZU	Histidine kinase
X953_08485	ENOG4105U5Y	Transcriptional regulator
X953_08490	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
X953_08500	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
X953_08510	ENOG4108KKH	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
X953_08520	ENOG4105KBJ	sporulation protein ytfj
X953_08525	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
X953_08540	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
X953_08545	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
X953_08550	ENOG4107YZX	Universal stress protein
X953_08565	ENOG41087YS	Phage shock protein A
X953_08580	ENOG4108JPV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
X953_08585	ENOG4105E8R	UPF0173 metal-dependent hydrolase
X953_08605	ENOG4107QHF	type ii secretion system protein e
X953_08610	ENOG4105CZX	twitching motility protein
X953_08615	ENOG4105D7Q	type ii secretion system
X953_08625	ENOG4106A3R	peptidase
X953_08660	ENOG4105SFS	phosphoesterase RecJ domain protein
X953_08675	ENOG4105VV2	
X953_08680	ENOG4105C0B	DNA polymerase III (alpha subunit)
X953_08685	ENOG4105C6K	Malic enzyme
X953_08690	ENOG41073TP	transcriptional regulator
X953_08695	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
X953_08700	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
X953_08705	ENOG4105CTQ	phosphohexokinase
X953_08710	ENOG4105CA9	Pyruvate kinase
X953_08715	ENOG4105FS0	cytoplasmic membrane protein
X953_08720	ENOG4108REF	Sporulation integral membrane protein ytvi
X953_08725	ENOG4105BZN	citrate synthase
X953_08730	ENOG4108HMX	isocitrate dehydrogenase (NADP)
X953_08735	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
X953_08745	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
X953_08750	ENOG4105BZU	Histidine kinase
X953_08755	ENOG4105C2M	dna polymerase I
X953_08765	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
X953_08770	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
X953_08775	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
X953_08785	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
X953_08800	ENOG4108TDW	sporulation protein YtxC
X953_08805	ENOG4105C22	threonyL-tRNA synthetase
X953_08810	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
X953_08815	ENOG4105VJV	50s ribosomal protein L35
X953_08820	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
X953_08845	ENOG4105CN9	Peptidase m42 family protein
X953_08850	ENOG4105E4C	Lytic transglycosylase catalytic
X953_08855	ENOG4105CJ1	ABC, transporter
X953_08875	ENOG41067MF	small acid-soluble spore protein
X953_08880	ENOG4108RWN	rrna methyltransferase
X953_08890	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
X953_08895	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
X953_08900	ENOG410687F	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
X953_08910	ENOG4105DCG	PHP domain protein
X953_08915	ENOG4105C98	muts2 protein
X953_08930	ENOG4105CEY	Amp-dependent synthetase and ligase
X953_08935	ENOG4107Z3H	Transcriptional regulator, TetR family
X953_08940	ENOG41060WC	Enoyl-CoA hydratase
X953_08945	ENOG4105BZJ	Electron transfer flavoprotein
X953_08950	ENOG4105C10	Electron transfer flavoprotein
X953_08955	ENOG4105K63	Thioredoxin
X953_08960	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
X953_08970	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
X953_08980	ENOG4105E33	succinate dehydrogenase
X953_08990	ENOG4105PFC	Transcriptional regulator
X953_08995	ENOG41067TZ	transcriptional regulator, MarR family
X953_09000	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
X953_09005	ENOG4108XJQ	germination protein
X953_09010	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
X953_09015	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
X953_09020	ENOG4105M59	Phosphodiesterase, mj0936 family
X953_09040	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
X953_09045	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
X953_09055	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
X953_09060	ENOG4106PMH	Extracellular solute-binding protein family 3
X953_09065	ENOG4105E5Q	amino acid AbC transporter
X953_09080	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
X953_09090	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
X953_09100	ENOG4105D52	delta-aminolevulinic acid dehydratase
X953_09105	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
X953_09110	ENOG41068KH	stage VI sporulation protein D
X953_09110	ENOG41068KH	stage VI sporulation protein D
X953_09125	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
X953_09135	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
X953_09140	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
X953_09150	ENOG4105W5Q	DNA repair protein (RadC
X953_09160	ENOG4105DFF	Rod shape-determining protein mreb
X953_09165	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
X953_09175	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
X953_09180	ENOG4107QMS	site-determining protein
X953_09195	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
X953_09200	ENOG4105X36	(ribosomal) protein
X953_09205	ENOG4105K46	50S ribosomal protein l27
X953_09215	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
X953_09220	ENOG4105CQC	Prephenate dehydratase
X953_09225	ENOG4106678	morphogenetic protein associated with SpoVID
X953_09235	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
X953_09245	ENOG4105CDY	transcriptional regulatory protein
X953_09250	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
X953_09255	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
X953_09265	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
X953_09270	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
X953_09275	ENOG4105VIE	preprotein translocase, subunit YajC
X953_09285	ENOG4107R3E	Citrate transporter
X953_09290	ENOG4105CKP	Polysaccharide Biosynthesis Protein
X953_09300	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
X953_09305	ENOG41067VP	Protein of unknown function (DUF1049)
X953_09310	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
X953_09315	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
X953_09320	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
X953_09325	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
X953_09330	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
X953_09340	ENOG4105CUT	histidyl-tRNA synthetase
X953_09345	ENOG4105C9M	aspartyl-trna synthetase
X953_09350	ENOG4108VCI	transcription factor, rsfa family
X953_09355	ENOG4105D1H	recombination factor protein RarA
X953_09365	ENOG4105C3J	Cysteine desulfurase
X953_09370	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
X953_09380	ENOG4105C7H	Helicase, RecD TraA family
X953_09385	ENOG41060CR	
X953_09395	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
X953_09400	ENOG4105VBH	UPF0297 protein
X953_09405	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
X953_09420	ENOG4105HHA	aminodeoxychorismate lyase
X953_09425	ENOG4108VQJ	O-methyltransferase
X953_09430	ENOG4105DBI	uridine monophosphokinase
X953_09435	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
X953_09445	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
X953_09455	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
X953_09460	ENOG4105KJM	monovalent cation h antiporter subunit g
X953_09470	ENOG4105SC1	monovalent cation H antiporter subunit E
X953_09475	ENOG4108JPZ	Monovalent cation H antiporter subunit D
X953_09480	ENOG4105MKQ	Monovalent cation H antiporter subunit C
X953_09485	ENOG4105D65	subunit l
X953_09495	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
X953_09500	ENOG4105CQW	ribosome biogenesis GTPase YqeH
X953_09505	ENOG4105E2X	shikimate dehydrogenase
X953_09510	ENOG410812S	Rna-binding protein
X953_09515	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
X953_09520	ENOG4108WF2	Metal Dependent Phosphohydrolase
X953_09530	ENOG4105DXX	methyltransferase
X953_09535	ENOG4105KQC	Competence protein
X953_09540	ENOG4108UK2	deaminase
X953_09545	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
X953_09555	ENOG4105TQK	DNA polymerase iii, delta' subunit
X953_09560	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
X953_09565	ENOG4105CEF	Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity)
X953_09570	ENOG4108ZRV	stage ii sporulation protein p
X953_09580	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
X953_09585	ENOG4105CSA	Coproporphyrinogen iii oxidase
X953_09590	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
X953_09595	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
X953_09600	ENOG4105CFG	Acts as a chaperone (By similarity)
X953_09605	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
X953_09610	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
X953_09615	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
X953_09620	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
X953_09625	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
X953_09630	ENOG4105VCC	30S ribosomal protein S21
X953_09635	ENOG4105KTH	gatB Yqey
X953_09640	ENOG4105F7J	membrane-bound serine protease
X953_09645	ENOG4105DI5	UPF0365 protein
X953_09655	ENOG41068P3	sporulation protein YqfC
X953_09665	ENOG4105C9A	Phoh family
X953_09670	ENOG4105CTJ	Metal Dependent Phosphohydrolase
X953_09675	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
X953_09685	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
X953_09695	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
X953_09705	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
X953_09710	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
X953_09720	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
X953_09725	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
X953_09730	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
X953_09750	ENOG4105EGD	dinuclear metal center protein, YbgI family
X953_09760	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
X953_09765	ENOG41069ZM	Protein of unknown function (DUF2624)
X953_09770	ENOG41063Y9	
X953_09830	ENOG4107RF6	penicillin-binding protein
X953_09845	ENOG4105WDJ	50S ribosomal protein L33
X953_09850	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
X953_09855	ENOG4105D06	uba thif-type nad fad binding protein
X953_09860	ENOG4107ZXI	Rhomboid family
X953_09880	ENOG4105DKQ	ROK family
X953_09890	ENOG4105C5X	domain protein
X953_10195	ENOG4108SVB	resolvase
X953_10200	ENOG4106855	Competence protein
X953_10225	ENOG4105C0D	helicase
X953_10235	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
X953_10240	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
X953_10245	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
X953_10250	ENOG4105WZW	rhodanese family
X953_10255	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
X953_10260	ENOG4105KST	dependent repressor
X953_10280	ENOG4105DC7	peptidase M24
X953_10285	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
X953_10290	ENOG4105CD2	stage iii sporulation protein aa
X953_10295	ENOG4105KR5	Stage iii sporulation protein
X953_10300	ENOG4108CQH	stage III sporulation protein AC
X953_10305	ENOG4105KQ4	Stage iii sporulation protein ad
X953_10315	ENOG410644B	Stage III sporulation protein af
X953_10335	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
X953_10340	ENOG4108ZSR	alkaline shock protein
X953_10345	ENOG4105M7K	Involved in the transcription termination process (By similarity)
X953_10350	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
X953_10355	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
X953_10360	ENOG41084DP	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
X953_10375	ENOG4105DX0	Hemolysin A
X953_10380	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
X953_10385	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
X953_10390	ENOG4105S1Z	Stage IV sporulation protein B
X953_10395	ENOG4107QQR	Sporulation
X953_10400	ENOG4105CFH	Aspartokinase
X953_10410	ENOG4108JUB	Transcriptional regulator
X953_10420	ENOG4107RDP	Dehydrogenase
X953_10440	ENOG4105CPP	Dehydrogenase, E1 component
X953_10445	ENOG4105C7S	Dehydrogenase
X953_10450	ENOG4108Y6J	UPF0403 protein
X953_10455	ENOG4108QEG	Membrane
X953_10470	ENOG4108ZVT	methylmalonyl-coA epimerase
X953_10475	ENOG4108HNZ	carboxyl transferase
X953_10480	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
X953_10485	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
X953_10490	ENOG4105C26	Dehydrogenase
X953_10495	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
X953_10500	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
X953_10505	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
X953_10515	ENOG41069FQ	Metallo-beta-lactamase superfamily
X953_10520	ENOG4108IXY	short-chain dehydrogenase reductase
X953_10530	ENOG4105CPC	Aldo Keto reductase
X953_10545	ENOG4105MZ9	stage II sporulation protein m
X953_10550	ENOG4105I3K	Ferric uptake regulator, Fur family
X953_10560	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
X953_10565	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
X953_10585	ENOG4105DZ1	carboxypeptidase
X953_10590	ENOG41082AN	stage II sporulation protein
X953_10595	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
X953_10600	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
X953_10620	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
X953_10625	ENOG4107ZE5	PPIases accelerate the folding of proteins
X953_10630	ENOG4105DZP	Membrane-associated zinc metalloprotease
X953_10645	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
X953_10650	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
X953_10655	ENOG4105DZ1	carboxypeptidase
X953_10660	ENOG4108JIC	nucleoside recognition domain protein
X953_10670	ENOG4105FE9	pseudouridine synthase
X953_10675	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
X953_10680	ENOG4107TWT	Cytochrome c biogenesis protein
X953_10685	ENOG4105CRE	cytochrome C
X953_10690	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
X953_10695	ENOG4105BZU	Histidine kinase
X953_10710	ENOG4105T7X	
X953_10715	ENOG4105C9U	ATP-dependent DNA helicase RecQ
X953_10720	ENOG4105I7S	Abortive infection protein
X953_10730	ENOG4107RGJ	metallophosphoesterase
X953_10735	ENOG4108S6Z	Negative regulator of genetic competence
X953_10745	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
X953_10750	ENOG4107RB3	L-asparaginase
X953_10755	ENOG4108PNU	Involved in the degradation of specific anti-sigma factors (By similarity)
X953_10760	ENOG4105F0V	Cell wall hydrolase
X953_10765	ENOG4105MSI	germination protein ypeb
X953_10780	ENOG4105CAT	Cytidine monophosphate kinase
X953_10790	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
X953_10800	ENOG4105S2F	
X953_10805	ENOG41065D1	
X953_10810	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
X953_10815	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
X953_10835	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
X953_10840	ENOG4105K70	DNA-binding protein
X953_10845	ENOG4105WP2	Tryptophan RNA-binding attenuator protein
X953_10850	ENOG4105XXQ	heptaprenyl diphosphate synthase component I
X953_10855	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
X953_10860	ENOG4105EAH	synthase
X953_10865	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
X953_10875	ENOG4105BZU	Histidine kinase
X953_10880	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
X953_10885	ENOG4105D49	3-dehydroquinate synthase
X953_10890	ENOG4105KHN	chorismate mutase
X953_10895	ENOG4105CIH	Imidazole acetol-phosphate transaminase
X953_10905	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
X953_10915	ENOG4108SXZ	UPF0302 protein
X953_10930	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
X953_10935	ENOG4105PE6	Menaquinol-cytochrome c reductase, cytochrome b c subunit
X953_10955	ENOG4108JYZ	YitT family
X953_10960	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
X953_10965	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
X953_10970	ENOG4108Z5K	methylglyoxal synthase
X953_10975	ENOG4105CPK	Glycosyl transferase (Group 1
X953_10980	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
X953_10995	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
X953_11000	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
X953_11005	ENOG4105DVT	helicase
X953_11010	ENOG4105YAC	
X953_11020	ENOG4105CHM	Aminotransferase
X953_11025	ENOG4105C5S	asparaginyl-tRNA synthetase
X953_11035	ENOG4105CSM	endonuclease III
X953_11040	ENOG4105BZ4	penicillin-binding protein
X953_11045	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
X953_11070	ENOG4105KG3	cytidine deaminase
X953_11075	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
X953_11085	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
X953_11090	ENOG4105CTD	carboxy-peptidase
X953_11095	ENOG41065KQ	synthase
X953_11110	ENOG4107RQ2	Cytochrome c oxidase, subunit I
X953_11115	ENOG4105NAA	Cytochrome C oxidase, subunit II
X953_11135	ENOG4105VEQ	Cold shock protein
X953_11155	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
X953_11160	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
X953_11170	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
X953_11175	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
X953_11180	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
X953_11200	ENOG4105E0X	reductase
X953_11220	ENOG41084AG	Acylphosphatase
X953_11245	ENOG4108IUE	nitrate reductase beta subunit
X953_11265	ENOG4105C6T	cysteine synthase
X953_11285	ENOG410890F	Dynamin family
X953_11290	ENOG4105MXW	flavin reductase domain protein, FMN-binding
X953_11295	ENOG4107QX3	carboxylase
X953_11300	ENOG4105E39	Enoyl-CoA hydratase
X953_11305	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
X953_11310	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
X953_11315	ENOG4105CEY	Amp-dependent synthetase and ligase
X953_11320	ENOG4105C1G	acyl-Coa dehydrogenase
X953_11325	ENOG4105U5Y	Transcriptional regulator
X953_11335	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
X953_11340	ENOG4105K4P	CoA-binding domain protein
X953_11345	ENOG4105E90	ABC transporter
X953_11355	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
X953_11360	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
X953_11365	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
X953_11370	ENOG4105MI2	
X953_11380	ENOG41067CD	Small, acid-soluble spore protein Tlp
X953_11385	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
X953_11395	ENOG4108I0Z	Aconitate hydratase
X953_11400	ENOG4105BZU	Histidine kinase
X953_11415	ENOG4107YTP	response regulator receiver protein
X953_11420	ENOG4105HC0	Na H antiporter
X953_11425	ENOG4107QIV	Cytochrome c biogenesis protein
X953_11430	ENOG4105VXM	UPF0154 protein
X953_11445	ENOG4105VPS	UPF0291 protein
X953_11450	ENOG4108SVB	resolvase
X953_11460	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
X953_11465	ENOG4105C5F	glutamine synthetase
X953_11470	ENOG4105KV4	Transcriptional regulator
X953_11475	ENOG4105CXI	aluminum resistance protein
X953_11480	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
X953_11485	ENOG4106F1P	AAA ATPase, central domain protein
X953_11495	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
X953_11500	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
X953_11505	ENOG4108WPJ	Ferritin-like domain
X953_11510	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
X953_11515	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
X953_11530	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
X953_11535	ENOG4105MCT	stage V sporulation protein S
X953_11540	ENOG4105D48	metallophosphoesterase
X953_11545	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
X953_11550	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
X953_11555	ENOG4105CEV	competence damage-inducible protein
X953_11560	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
X953_11575	ENOG4105XZV	Protein of unknown function (DUF3243)
X953_11580	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
X953_11600	ENOG4105UIB	(ABC) transporter
X953_11605	ENOG4108JQ9	ABC transporter
X953_11610	ENOG4105DIH	basic membrane
X953_11615	ENOG4105FDP	GntR family transcriptional regulator
X953_11620	ENOG4105CNU	cell division protein FtsK
X953_11630	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
X953_11635	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
X953_11645	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
X953_11650	ENOG4108S0H	Dipicolinic acid synthetase, b subunit
X953_11655	ENOG4105E35	Dipicolinate synthase subunit A
X953_11675	ENOG4105C1V	Peptidase, M16
X953_11695	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
X953_11700	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
X953_11705	ENOG4105DTN	riboflavin biosynthesis protein ribF
X953_11710	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
X953_11715	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
X953_11725	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
X953_11730	ENOG4105VHM	ribosomal protein
X953_11735	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
X953_11740	ENOG4105CHV	Transcription elongation factor NusA
X953_11745	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
X953_11750	ENOG4107MMM	Anti-sigma-factor antagonist
X953_11755	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
X953_11760	ENOG4105DZP	Membrane-associated zinc metalloprotease
X953_11765	ENOG4105KNE	Phosphatidate cytidylyltransferase
X953_11770	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
X953_11780	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
X953_11785	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
X953_11790	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
X953_11795	ENOG4105CE9	30S ribosomal protein S2
X953_11820	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
X953_11825	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
X953_11835	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
X953_11840	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
X953_11850	ENOG4105FZW	flagellar biosynthesis regulator FlhF
X953_11855	ENOG4105D7B	Flagellar biosynthesis protein flha
X953_11860	ENOG4105D00	flagellar biosynthetic protein flhB
X953_11865	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
X953_11870	ENOG4105VS8	Flagellar biosynthetic protein fliq
X953_11875	ENOG4105CN7	Flagellar biosynthetic protein FliP
X953_11885	ENOG4107YTP	response regulator receiver protein
X953_11890	ENOG4105DD5	Flagellar motor switch protein
X953_11895	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
X953_11905	ENOG41068WV	flagellar FlbD family protein
X953_11910	ENOG4108JQA	flagellar
X953_11920	ENOG410822I	Flagellar hook capping protein
X953_11950	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
X953_11955	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
X953_11960	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
X953_11965	ENOG4108ZC9	flagellar basal-body rod protein flgc
X953_11970	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
X953_11975	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
X953_11980	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
X953_11985	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
X953_11990	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
X953_12000	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
X953_12005	ENOG4105C79	DNA protecting protein DprA
X953_12010	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
X953_12015	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
X953_12020	ENOG4105D00	flagellar biosynthetic protein flhB
X953_12030	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
X953_12035	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
X953_12045	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
X953_12050	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
X953_12055	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
X953_12065	ENOG4105VB6	UPF0109 protein
X953_12070	ENOG4105K5M	30s ribosomal protein S16
X953_12080	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
X953_12085	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
X953_12090	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
X953_12095	ENOG4108CPA	Protein of unknown function (DUF1128)
X953_12100	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
X953_12105	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
X953_12110	ENOG4105CHR	reductase
X953_12115	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
X953_12120	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
X953_12125	ENOG4108VVV	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity)
X953_12130	ENOG4105CB5	ATP-dependent DNA helicase recG
X953_12135	ENOG4105EJQ	L-serine dehydratase
X953_12150	ENOG4105DP4	dak2 domain fusion protein ylov
X953_12155	ENOG4108ZAA	Alkaline-shock protein
X953_12160	ENOG4105VB9	50S ribosomal protein l28
X953_12170	ENOG4105FJ0	thiamine
X953_12175	ENOG4105DJV	ribulose-phosphate 3-epimerase
X953_12180	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
X953_12185	ENOG4105D9P	serine threonine protein kinase
X953_12190	ENOG4108ZF3	Phosphatase
X953_12195	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
X953_12200	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
X953_12205	ENOG4105C25	Primosomal protein n'
X953_12210	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
X953_12215	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
X953_12220	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
X953_12225	ENOG4105KC4	UPF0296 protein
X953_12235	ENOG4105F23	Fibronectin-binding protein
X953_12240	ENOG4108ZHJ	Organic hydroperoxide resistance protein
X953_12245	ENOG4108KAM	Transcriptional regulator
X953_12250	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
X953_12255	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
X953_12260	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
X953_12265	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
X953_12270	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
X953_12275	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
X953_12285	ENOG4105CXT	aspartate transcarbamylase
X953_12290	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
X953_12295	ENOG4105C34	Pseudouridine synthase
X953_12300	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
X953_12305	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
X953_12315	ENOG4105DBK	s4 domain protein
X953_12320	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
X953_12325	ENOG4105DFA	alanine racemase domain protein
X953_12330	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
X953_12335	ENOG4105WR5	sporulation protein, YlmC YmxH family
X953_12345	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
X953_12350	ENOG4108AWX	Sporulation factor SpoIIGA 
X953_12355	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
X953_12360	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
X953_12365	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
X953_12370	ENOG4105CNI	cell division protein FtsW
X953_12375	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
X953_12380	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
X953_12385	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
X953_12390	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
X953_12395	ENOG4105CJN	penicillin-binding protein
X953_12400	ENOG4105CJN	penicillin-binding protein
X953_12405	ENOG41068DC	Essential cell division protein (By similarity)
X953_12410	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
X953_12415	ENOG4108V6E	Cell division protein mraZ
X953_12420	ENOG41074B2	UPF0747 protein
X953_12435	ENOG4108YG3	N-acetyltransferase
X953_12445	ENOG4105E39	Enoyl-CoA hydratase
X953_12450	ENOG41067VY	50S ribosomal protein L32
X953_12460	ENOG4105CDE	UPF0348 protein
X953_12465	ENOG41063PX	domain protein
X953_12470	ENOG4105H20	Sporulation integral membrane protein YlbJ
X953_12475	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
X953_12480	ENOG4106H78	methyltransferase
X953_12485	ENOG4105WUC	UPF0298 protein
X953_12505	ENOG4106UY4	Inherit from COG: Scp-like extracellular
X953_12520	ENOG4108SJC	Membrane
X953_12535	ENOG4105CCU	oxidase (Subunit III)
X953_12540	ENOG4105BZ9	Cytochrome C oxidase, subunit I
X953_12550	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
X953_12555	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
X953_12560	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
X953_12565	ENOG4105CNI	cell division protein FtsW
X953_12570	ENOG4105ZPI	UPF0358 protein
X953_12595	ENOG4105QA2	
X953_12605	ENOG4105ECY	inositol monophosphatase
X953_12620	ENOG4105WBI	UPF0223 protein
X953_12625	ENOG4105EA8	2-Nitropropane dioxygenase
X953_12630	ENOG4105CXN	decarboxylase
X953_12665	ENOG4105CPP	Dehydrogenase, E1 component
X953_12680	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
X953_12685	ENOG4108X4Q	Hydrolase
X953_12690	ENOG4106148	UPF0356 protein
X953_12695	ENOG4105CN5	Metallo-Beta-Lactamase
X953_12705	ENOG4107ZYR	domain protein
X953_12710	ENOG4105BZ1	(ABC) transporter
X953_12715	ENOG4105BZ1	(ABC) transporter
X953_12720	ENOG4107R19	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
X953_12725	ENOG4105D3R	alkyl hydroperoxide reductase
X953_12735	ENOG4105CH2	amidohydrolase
X953_12740	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
X953_12750	ENOG4105KTU	Transcriptional regulator, arsr family
X953_12755	ENOG4105PGM	cation diffusion facilitator family transporter
X953_12770	ENOG4105UIN	
X953_12785	ENOG4108TVT	permease
X953_12790	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
X953_12800	ENOG4105CHM	Aminotransferase
X953_12810	ENOG4105C3F	Signal peptidase i
X953_12820	ENOG4105C0H	protease
X953_12825	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
X953_12840	ENOG4105CK7	Sodium proline symporter
X953_12855	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
X953_12860	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
X953_12880	ENOG41090VF	Stage v sporulation protein ac
X953_12885	ENOG4105CZ3	stage V sporulation protein ad
X953_12900	ENOG4108QY0	Membrane
X953_12910	ENOG4105CB2	alcohol dehydrogenase
X953_12915	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
X953_12925	ENOG4105D22	carbon starvation protein
X953_12935	ENOG4108HIZ	formate dehydrogenase alpha subunit
X953_12940	ENOG4105D82	Glutamate dehydrogenase
X953_12960	ENOG4105N67	Proton-coupled thiamine transporter YuaJ
X953_12965	ENOG4108YYC	ycei family
X953_12970	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
X953_12975	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
X953_12980	ENOG4105J76	Periplasmic binding protein
X953_13000	ENOG4105CEP	NADH dehydrogenase
X953_13015	ENOG4105CEY	Amp-dependent synthetase and ligase
X953_13030	ENOG4105EEQ	Na H antiporter
X953_13050	ENOG4105JQZ	Methyltransferase
X953_13065	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
X953_13075	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
X953_13085	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
X953_13090	ENOG4107ZE5	PPIases accelerate the folding of proteins
X953_13100	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
X953_13105	ENOG4108JPW	Aminotransferase
X953_13120	ENOG4105R40	Glycine betaine carnitine choline
X953_13125	ENOG4108HQR	Glycine betaine
X953_13130	ENOG4105E90	ABC transporter
X953_13140	ENOG4107HG4	Transcriptional regulator
X953_13150	ENOG4105E35	Dipicolinate synthase subunit A
X953_13160	ENOG4105DZC	cytosine deaminase
X953_13165	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
X953_13190	ENOG41085GJ	domain protein
X953_13200	ENOG4105C8T	Leucyl-tRNA synthetase
X953_13210	ENOG4108Z0R	Transferase
X953_13215	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
X953_13220	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
X953_13225	ENOG4105D2X	ABC transporter substrate-binding protein
X953_13235	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
X953_13255	ENOG4105E0A	ABC, transporter
X953_13260	ENOG4105CEY	Amp-dependent synthetase and ligase
X953_13265	ENOG4108IPT	Naphthoate synthase
X953_13270	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
X953_13275	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
X953_13280	ENOG4105E4F	Isochorismate synthase
X953_13285	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
X953_13290	ENOG4105KA0	thioesterase Superfamily protein
X953_13300	ENOG4108SAX	Membrane
X953_13310	ENOG4105CN9	Peptidase m42 family protein
X953_13320	ENOG4107PBV	potassium channel
X953_13335	ENOG4105WG9	Conserved Protein
X953_13340	ENOG4107QYV	phosphohexose isomerase
X953_13345	ENOG4105C87	Aminotransferase class I and II
X953_13350	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
X953_13360	ENOG4105Y38	Kinase-associated protein B
X953_13365	ENOG4105KRI	phosphocarrier protein (HPr
X953_13370	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
X953_13380	ENOG41069ER	domain protein
X953_13390	ENOG4105CEP	NADH dehydrogenase
X953_13395	ENOG4105CAY	ferredoxin--nadp reductase
X953_13400	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
X953_13405	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
X953_13415	ENOG41083MR	nifu domain-containing protein
X953_13420	ENOG4105C5I	Dehydrogenase
X953_13430	ENOG4108W5N	phosphatidylglycerophosphatase a
X953_13435	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
X953_13455	ENOG4105EUF	amidase EC 3.5.1.4
X953_13465	ENOG4105MMD	transcriptional regulator
X953_13470	ENOG4106EGE	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
X953_13475	ENOG4105FAA	peptidase M23
X953_13485	ENOG4105C8J	)-transporter
X953_13490	ENOG4107S6Z	Na H antiporter
X953_13495	ENOG4108YTE	sporulation protein YunB
X953_13500	ENOG4108ESY	Metal dependent phosphohydrolase
X953_13505	ENOG4105KZD	Domain of unknown function (DUF1805)
X953_13510	ENOG4107R8B	5'-nucleotidase
X953_13520	ENOG4105DIW	FeS assembly protein SUFB
X953_13525	ENOG4108UNV	SUF system FeS assembly protein, NifU family
X953_13530	ENOG4105C9B	Cysteine desulfurase
X953_13535	ENOG4105JRK	feS assembly protein SufD
X953_13540	ENOG4105C3K	feS assembly ATPase SufC
X953_13550	ENOG4105D01	(LipO)protein
X953_13555	ENOG4108UMI	ABC transporter, permease
X953_13560	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
X953_13575	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
X953_13580	ENOG41080E8	Transcriptional regulator, Spx MgsR family
X953_13585	ENOG4105C1G	acyl-Coa dehydrogenase
X953_13590	ENOG4105CHU	acetyl-coa acetyltransferase
X953_13610	ENOG4105C59	p-type ATPase
X953_13615	ENOG4105VPX	protein, conserved in bacteria
X953_13625	ENOG4105FDK	ABC transporter
X953_13635	ENOG4105N80	Ferric uptake regulator, Fur family
X953_13640	ENOG4105WMR	Protein CrcB homolog
X953_13645	ENOG4105WMR	Protein CrcB homolog
X953_13660	ENOG4105Z8B	NlpC/P60 family
X953_13670	ENOG4107QP3	malate synthase g
X953_13680	ENOG4108V3A	UPF0421 protein
X953_13685	ENOG4105WH1	Two component transcriptional regulator luxr family
X953_13690	ENOG4105ENE	Histidine kinase
X953_13710	ENOG4107RGD	Major Facilitator superfamily
X953_13715	ENOG4105DEN	Luciferase family
X953_13725	ENOG4108UT2	hemolysin iii
X953_13730	ENOG4105DER	m42 family
X953_13735	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
X953_13740	ENOG4105DSE	periplasmic solute binding protein
X953_13745	ENOG4105CC5	ABC transporter
X953_13750	ENOG4105DIK	(ABC) transporter
X953_13765	ENOG4105XZU	Preprotein translocase, subunit SecG
X953_13775	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
X953_13790	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
X953_13795	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
X953_13800	ENOG4105CP7	Triose-phosphate isomerase
X953_13805	ENOG4105BZA	Phosphoglycerate kinase
X953_13825	ENOG4105VND	Ribonuclease
X953_13840	ENOG4105CY2	Citrate transporter
X953_13845	ENOG4105CHU	acetyl-coa acetyltransferase
X953_13850	ENOG4105DTD	Dehydrogenase
X953_13855	ENOG4108IIH	CoA-transferase subunit B
X953_13860	ENOG4105D6N	CoA-transferase, subunit a
X953_13885	ENOG4105FF2	Type I DHQase
X953_13890	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
X953_13900	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
X953_13905	ENOG4105KRI	phosphocarrier protein (HPr
X953_13910	ENOG4105CIE	May be required for sporulation (By similarity)
X953_13915	ENOG4105CHW	UPF0052 protein
X953_13920	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
X953_13925	ENOG4108Z4K	mutator MutT protein
X953_13930	ENOG4105C3M	thioredoxin reductase
X953_13940	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
X953_13945	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
X953_13960	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
X953_13965	ENOG4108S4C	acetyltransferase
X953_13970	ENOG4107XGZ	Hydrolase
X953_13975	ENOG4105HKU	nucleoside recognition domain-containing protein
X953_13980	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
X953_13985	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
X953_13990	ENOG41086DT	Membrane protein of unknown function
X953_13995	ENOG41067S9	phage shock protein C, PspC
X953_14000	ENOG4108TN2	lmbE family
X953_14010	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
X953_14015	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
X953_14020	ENOG4105CEI	nitrite reductase
X953_14030	ENOG4105CN1	protease
X953_14035	ENOG4105DR5	peptidase
X953_14040	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
X953_14045	ENOG4105CAK	Cell division ATP-binding protein ftsE
X953_14055	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
X953_14060	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
X953_14070	ENOG4105MS2	ribosomal subunit Interface protein
X953_14075	ENOG41069ZS	flagellar protein
X953_14080	ENOG4105MQ3	flagellar protein FliS
X953_14085	ENOG41083S7	flagellar protein FlaG
X953_14090	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
X953_14095	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
X953_14105	ENOG4105DTJ	flagellar hook-associated protein
X953_14110	ENOG4105E1Q	flagellar hook-associated protein
X953_14125	ENOG4105RU3	
X953_14130	ENOG41081UC	Inherit from COG: Competence protein
X953_14145	ENOG4105WH1	Two component transcriptional regulator luxr family
X953_14150	ENOG4105BZU	Histidine kinase
X953_14155	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
X953_14160	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
X953_14165	ENOG4105CE4	GlcNAc 6-P deacetylase
X953_14170	ENOG4105CI1	PTS System
X953_14200	ENOG4105VFR	signal peptidase
X953_14225	ENOG4108KGH	TRANSCRIPTIONal
X953_14230	ENOG4107RVG	penicillin-binding protein
X953_14250	ENOG4105C26	Dehydrogenase
X953_14265	ENOG410605W	Major Facilitator
X953_14275	ENOG4105E7W	lamb ycsf family protein
X953_14280	ENOG4105P4J	Allophanate hydrolase, subunit 1
X953_14285	ENOG4105C8P	)-transporter
X953_14290	ENOG4105D94	Major Facilitator Superfamily
X953_14295	ENOG4105DJ2	Major Facilitator Superfamily
X953_14305	ENOG4105E0M	Sulfatase
X953_14310	ENOG4105C8Q	Methyl-accepting chemotaxis
X953_14315	ENOG4105WH1	Two component transcriptional regulator luxr family
X953_14320	ENOG4105C8Q	Methyl-accepting chemotaxis
X953_14325	ENOG4105BZU	Histidine kinase
X953_14330	ENOG4107YTP	response regulator receiver protein
X953_14335	ENOG4108V3W	Chemotaxis protein, CheW
X953_14340	ENOG4105CBS	Chea signal transduction histidine kinase
X953_14350	ENOG4105ER2	Ompa motb domain protein
X953_14355	ENOG4105E14	MotA TolQ exbB proton channel
X953_14360	ENOG4107RT6	flagellar hook-associated
X953_14380	ENOG4106YBV	Methyl-accepting chemotaxis
X953_14390	ENOG4105CK7	Sodium proline symporter
X953_14405	ENOG4105D17	glycoside hydrolase, family 3 domain protein
X953_14410	ENOG4105EHZ	conserved protein UCP016719
X953_14415	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
X953_14420	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
X953_14430	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
X953_14440	ENOG4105RD7	BadF BadG BcrA BcrD
X953_14445	ENOG4105NQC	Flavodoxin
X953_14460	ENOG4105C7Z	Conserved Protein
X953_14510	ENOG4105QNR	S1 RNA binding domain protein
X953_14535	ENOG4108X4Q	Hydrolase
X953_14555	ENOG4108MRH	transcriptional regulatory protein
X953_14560	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
X953_14570	ENOG4105CXY	transporter
X953_14575	ENOG4105C7B	Threonine dehydratase
X953_14590	ENOG4105BZW	Glycerate kinase
X953_14595	ENOG4105E66	phosphoriboisomerase A
X953_14605	ENOG4105DEF	Extracellular solute-binding protein, family 5
X953_14615	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
X953_14620	ENOG4108JQ7	(ABC) transporter
X953_14630	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
X953_14635	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
X953_14650	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
X953_14655	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
X953_14665	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
X953_14690	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
X953_14695	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
X953_14700	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
X953_14705	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
X953_14710	ENOG4108ZP8	Acetolactate synthase small subunit
X953_14715	ENOG4105C7K	acetolactate synthase
X953_14720	ENOG4105C01	Dihydroxy-acid dehydratase
X953_14725	ENOG4105C09	Bile acid
X953_14730	ENOG4105EFZ	amidohydrolase
X953_14745	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
X953_14760	ENOG4105CH2	amidohydrolase
X953_14765	ENOG4105KME	endoribonuclease L-psp
X953_14770	ENOG4105C26	Dehydrogenase
X953_14775	ENOG4108JPW	Aminotransferase
X953_14780	ENOG4105DRR	Transcriptional regulator, GntR family
X953_14785	ENOG4105C5I	Dehydrogenase
X953_14845	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
X953_14850	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
X953_14865	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
X953_14880	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
X953_14885	ENOG4105DCF	alanine dehydrogenase
X953_14890	ENOG4105FDP	GntR family transcriptional regulator
X953_14895	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
X953_14905	ENOG4105E5Q	amino acid AbC transporter
X953_14910	ENOG4107R0W	ABC transporter
X953_14915	ENOG4105C26	Dehydrogenase
X953_14920	ENOG4105ETU	transcriptional activator (TenA
X953_14925	ENOG4105C94	Transporter
X953_14935	ENOG4105NQN	cytochrome C
X953_14940	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
X953_14945	ENOG4105BZ9	Cytochrome C oxidase, subunit I
X953_14975	ENOG4105EYH	Exonuclease
X953_14980	ENOG4107RFY	SbcCD D subunit
X953_15005	ENOG4107MII	Sugar-specific transcriptional regulator TrmB
X953_15010	ENOG4105CZM	Major Facilitator
X953_15015	ENOG4105DWF	phosphomethylpyrimidine kinase
X953_15025	ENOG4105C4B	ABC transporter, permease
X953_15040	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
X953_15045	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
X953_15060	ENOG4105DE4	1-phosphofructokinase
X953_15065	ENOG4105D2M	Aldolase
X953_15075	ENOG4105E70	isomerase
X953_15080	ENOG4105FDP	GntR family transcriptional regulator
X953_15095	ENOG4105CBG	Sulfatase
X953_15125	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
X953_15130	ENOG4105DTE	Xanthine uracil vitamin C permease
X953_15140	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
X953_15150	ENOG4105D7V	transposase
X953_15180	ENOG4105EU0	Major facilitator Superfamily
X953_15205	ENOG4105VKD	bioY protein
X953_15215	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
X953_15220	ENOG4108ZSU	Uncharacterized conserved protein (DUF2294)
X953_15230	ENOG4108UZX	fmn reductase
X953_15245	ENOG4105C26	Dehydrogenase
X953_15265	ENOG410756H	nucleotidyltransferase
X953_15280	ENOG4105J8Z	peptidase S8 and S53, subtilisin, kexin, sedolisin
X953_15285	ENOG4105F22	Major Facilitator Superfamily
X953_15290	ENOG4108IGT	Dipeptidase
X953_15295	ENOG4105DTQ	mandelate racemase muconate lactonizing
X953_15300	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
X953_15305	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
X953_15315	ENOG4108JYZ	YitT family
X953_15320	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
X953_15325	ENOG4105DEN	Luciferase family
X953_15330	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
X953_15335	ENOG4107QR9	Iron-sulfur cluster binding protein
X953_15340	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
X953_15345	ENOG4105JXH	GntR family transcriptional regulator
X953_15350	ENOG4105DAA	L-lactate
X953_15365	ENOG4107SCR	N-acetylneuraminate lyase
X953_15370	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
X953_15385	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
X953_15440	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
X953_15450	ENOG4105CHR	reductase
X953_15455	ENOG4107R8N	Glycosyl transferase, family 2
X953_15475	ENOG4105WH1	Two component transcriptional regulator luxr family
X953_15490	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
X953_15495	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
X953_15510	ENOG4105KME	endoribonuclease L-psp
X953_15520	ENOG4105C94	Transporter
X953_15540	ENOG4105BZ1	(ABC) transporter
X953_15550	ENOG4105C26	Dehydrogenase
X953_15555	ENOG4105C8Q	Methyl-accepting chemotaxis
X953_15565	ENOG4105ETE	Transcriptional regulator (LacI family
X953_15585	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
X953_15595	ENOG4105DT3	PTS system, galactitol-specific IIc component
X953_15600	ENOG4105JF0	Phosphoenolpyruvate-dependent sugar phosphotransferase system, eiia 2
X953_15605	ENOG4105D06	uba thif-type nad fad binding protein
X953_15610	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
X953_15615	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
X953_15620	ENOG41080HI	glycine oxidase
X953_15625	ENOG4108VEU	Thiamine monophosphate synthase
X953_15660	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
X953_15665	ENOG4105EHZ	conserved protein UCP016719
X953_15670	ENOG4105D17	glycoside hydrolase, family 3 domain protein
X953_15675	ENOG4105DRS	transport system, permease
X953_15680	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
X953_15690	ENOG4105CFC	Transporter
X953_15695	ENOG4107QP6	Xylose isomerase domain protein TIM barrel
X953_15700	ENOG4105CK5	oxidoreductase
X953_15715	ENOG4105CK5	oxidoreductase
X953_15730	ENOG4107T3P	ABC, transporter
X953_15735	ENOG4108PSK	reductase
X953_15740	ENOG4105ETE	Transcriptional regulator (LacI family
X953_15750	ENOG4105C0A	alcohol dehydrogenase
X953_15755	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
X953_15760	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
X953_15765	ENOG4105FDP	GntR family transcriptional regulator
X953_15780	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
X953_15785	ENOG4105KVH	Transcriptional regulator
X953_15795	ENOG4105E6M	Sulphatase-modifying factor protein
X953_15810	ENOG4105DZC	cytosine deaminase
X953_15815	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
X953_15835	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
X953_15845	ENOG41067TZ	transcriptional regulator, MarR family
X953_15850	ENOG4105EYF	MMPL domain protein
X953_15895	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
X953_15905	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
X953_15920	ENOG4108JQ7	(ABC) transporter
X953_15925	ENOG4105C3U	ABC transporter
X953_15930	ENOG4105C26	Dehydrogenase
X953_15935	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
X953_15940	ENOG4105DFD	Na H antiporter
X953_15950	ENOG4105CTU	Proline racemase
X953_15955	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
X953_15985	ENOG4108ME1	Peptidase M55 D-aminopeptidase
X953_15995	ENOG4108JQ7	(ABC) transporter
X953_16000	ENOG4105C3U	ABC transporter
X953_16005	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
X953_16010	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
X953_16015	ENOG4105DEF	Extracellular solute-binding protein, family 5
X953_16065	ENOG4105PAD	Hydrolase
X953_16080	ENOG4105C5F	glutamine synthetase
X953_16085	ENOG4105BZ8	glutamate synthase
X953_16090	ENOG4105CBC	glutamate synthase
X953_16095	ENOG4105C5Q	Transcriptional regulator
X953_16100	ENOG4105CAQ	asparagine synthetase
X953_16105	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
X953_16115	ENOG4106ANW	SMI1_KNR4
X953_16120	ENOG4106BHF	
X953_16130	ENOG4107EV6	Inherit from COG: YD repeat protein
X953_16155	ENOG4105I5R	Uncharacterized protein conserved in bacteria (DUF2334)
X953_16160	ENOG4107R8N	Glycosyl transferase, family 2
X953_16175	ENOG4107QJE	Chromosome Partitioning Protein
X953_16190	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
X953_16200	ENOG4108K88	Membrane
X953_16205	ENOG4105DTQ	mandelate racemase muconate lactonizing
X953_16220	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
X953_16225	ENOG4106A7E	Transcriptional regulator
X953_16380	ENOG4106KNT	transcriptional regulator
X953_16390	ENOG4105F3R	pts system mannose fructose sorbose family iid
X953_16395	ENOG4105ETZ	PTS System
X953_16400	ENOG4108EQA	pts system
X953_16435	ENOG4105I03	Flagellin
X953_16495	ENOG4105C0P	Mg chelatase subunit ChlI
X953_16555	ENOG41068WN	
X953_16560	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
X953_16565	ENOG4108JU4	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
X953_16570	ENOG4105D3Q	Sugar transferase
X953_16575	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
X953_16590	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
X953_16610	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
X953_16615	ENOG4107YJ4	chain length determinant protein
X953_16620	ENOG4105HTX	biosynthesis protein
X953_16660	ENOG4106IQC	argininosuccinate lyase
X953_16670	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
X953_16675	ENOG4105C4Y	ABC transporter
X953_16695	ENOG4105E2R	ROK family
X953_16715	ENOG4107RUZ	Sss sodium solute transporter superfamily
X953_16720	ENOG4105DG6	mannose-6-phosphate isomerase
X953_16725	ENOG4105DKQ	ROK family
X953_16740	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
X953_16750	ENOG4105EQD	regulatoR
X953_16755	ENOG4105C2F	Histidine kinase
X953_16760	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
X953_16775	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
X953_16790	ENOG4105EQD	regulatoR
X953_16795	ENOG4105C2F	Histidine kinase
X953_16800	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
X953_16810	ENOG4105CMR	udp-glucose 4-epimerase
X953_16820	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
X953_16825	ENOG4106N3A	copper homeostasis protein cutc
X953_16840	ENOG4105ETD	TRANSCRIPTIONal
X953_16850	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
X953_16865	ENOG4105DY9	regulatoR
X953_16900	ENOG4108KGH	TRANSCRIPTIONal
X953_16905	ENOG4105ESV	Glycosyl transferase, family 4
X953_16910	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
X953_16920	ENOG4105K64	Glycosyl transferase, family 2
X953_16940	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
X953_16990	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
X953_16995	ENOG4107RZX	Teichoic acid biosynthesis protein
X953_17005	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
X953_17010	ENOG4107RZX	Teichoic acid biosynthesis protein
X953_17015	ENOG4105E0M	Sulfatase
X953_17030	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
X953_17035	ENOG4105ESV	Glycosyl transferase, family 4
X953_17055	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
X953_17070	ENOG4108MR7	Arylsulfotransferase
X953_17080	ENOG41080TC	multidrug resistance protein
X953_17085	ENOG410839T	multidrug resistance protein
X953_17105	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
X953_17125	ENOG41067SE	Tetr family transcriptional regulator
X953_17145	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
X953_17160	ENOG4105CGA	flagellar basal-body rod protein FlgG
X953_17170	ENOG4105DFF	Rod shape-determining protein mreb
X953_17175	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
X953_17190	ENOG4105FRN	stage II sporulation protein
X953_17205	ENOG4108JQ7	(ABC) transporter
X953_17210	ENOG4107SN7	NLP P60 protein
X953_17215	ENOG4105DTQ	mandelate racemase muconate lactonizing
X953_17220	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
X953_17230	ENOG4105C3U	ABC transporter
X953_17235	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
X953_17240	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
X953_17245	ENOG4108ME1	Peptidase M55 D-aminopeptidase
X953_17250	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
X953_17270	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
X953_17275	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
X953_17280	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
X953_17285	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
X953_17290	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
X953_17295	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
X953_17300	ENOG4105WS6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
X953_17305	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
X953_17315	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
X953_17320	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
X953_17325	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
X953_17330	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
X953_17335	ENOG4108UIC	UPF0340 protein
X953_17340	ENOG4108YZG	isomerase
X953_17345	ENOG4105C8Q	Methyl-accepting chemotaxis
X953_17350	ENOG4107WAU	Protein tyrosine phosphatase
X953_17355	ENOG410815N	Probably functions as a manganese efflux pump (By similarity)
X953_17360	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
X953_17380	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
X953_17385	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
X953_17390	ENOG4107104	thymidine kinase
X953_17395	ENOG41082DI	50s ribosomal protein l31
X953_17400	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
X953_17405	ENOG4105CBT	Fructose-1,6-bisphosphatase
X953_17410	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
X953_17415	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
X953_17420	ENOG4105D2N	Aldolase
X953_17430	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
X953_17435	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
X953_17450	ENOG4105D5P	Methylmalonyl-coA mutase
X953_17460	ENOG4105DJT	lAO AO transport system ATPase
X953_17465	ENOG4105C1G	acyl-Coa dehydrogenase
X953_17470	ENOG4105C1G	acyl-Coa dehydrogenase
X953_17475	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
X953_17485	ENOG4105DF6	Fe-S oxidoreductase
X953_17490	ENOG4105C75	arginyL-tRNA synthetase
X953_17510	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
X953_17515	ENOG4105BZ4	penicillin-binding protein
X953_17520	ENOG4108XFG	YwhD family
X953_17530	ENOG4105DCI	Phosphohydrolase
X953_17535	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
X953_17540	ENOG4108IJ2	phosphate acetyltransferase
X953_17545	ENOG4107JTW	chlorite dismutase
X953_17565	ENOG4105M08	Membrane
X953_17580	ENOG4105CBC	glutamate synthase
X953_17595	ENOG4105DWD	nucleoside recognition domain protein
X953_17610	ENOG4105FDF	Could be involved in DNA repair (By similarity)
X953_17615	ENOG4105DQE	DNA ligase
X953_17625	ENOG4108X3M	OsmC Ohr family protein
X953_17640	ENOG4105K78	MarR family Transcriptional regulator
X953_17645	ENOG4107TS3	membrane protein, TerC
X953_17680	ENOG4105C9U	ATP-dependent DNA helicase RecQ
X953_17695	ENOG4108S4H	thioesterase Superfamily protein
X953_17700	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
X953_17705	ENOG4105C28	cystathionine
X953_17710	ENOG4105FR1	rard protein
X953_17720	ENOG41090WU	lipolytic protein G-D-S-L family
X953_17725	ENOG4105QZP	Uncharacterized protein conserved in bacteria (DUF2140)
X953_17745	ENOG4105C5H	ABC transporter
X953_17750	ENOG4105EXW	epimerase dehydratase
X953_17755	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
X953_17765	ENOG41069ER	domain protein
X953_17765	ENOG41069ER	domain protein
X953_17770	ENOG4105PTM	secreted protein
X953_17785	ENOG4107QW4	alcohol dehydrogenase
X953_17790	ENOG4105KME	endoribonuclease L-psp
X953_17825	ENOG4105CEY	Amp-dependent synthetase and ligase
X953_17830	ENOG4108JQ7	(ABC) transporter
X953_17840	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
X953_17845	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
X953_17870	ENOG4105C0D	helicase
X953_17875	ENOG4105CZM	Major Facilitator
X953_17880	ENOG4106KNT	transcriptional regulator
X953_17890	ENOG4105C6Z	Gluconate
X953_17895	ENOG4105CMG	Carbohydrate kinase
X953_17910	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
X953_17920	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
X953_17925	ENOG4108IUX	(ABC) transporter
X953_17940	ENOG4108WS4	fmn reductase
X953_17945	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
X953_17955	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
X953_17975	ENOG41068WN	
X953_17995	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
X953_18005	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
X953_18010	ENOG4105C5Q	Transcriptional regulator
X953_18015	ENOG4105D82	Glutamate dehydrogenase
X953_18020	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
X953_18050	ENOG4105C94	Transporter
X953_18060	ENOG410900G	Protein of unknown function (DUF421)
X953_18065	ENOG4105CAQ	asparagine synthetase
X953_18070	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
X953_18095	ENOG4105CH6	catalase
X953_18100	ENOG4105BZU	Histidine kinase
X953_18110	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
X953_18115	ENOG4105DEN	Luciferase family
X953_18120	ENOG4105CS1	NAD(P)H quinone oxidoreductase
X953_18125	ENOG4105D0M	Protease HtpX homolog
X953_18130	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
X953_18135	ENOG4108S01	response regulator
X953_18140	ENOG4108ZGX	Histidine kinase
X953_18145	ENOG4105ECK	Fatty Acid Desaturase
X953_18160	ENOG4105DVT	helicase
X953_18170	ENOG4105DY9	regulatoR
X953_18190	ENOG41067MG	lrgb family
X953_18200	ENOG4105CH7	arginosuccinase
X953_18205	ENOG4105CDH	Citrulline--aspartate ligase
X953_18210	ENOG4105KPY	Small multidrug resistance protein
X953_18215	ENOG4105KPY	Small multidrug resistance protein
X953_18230	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
X953_18245	ENOG4105CSM	endonuclease III
X953_18250	ENOG4105EXS	phosphate abc transporter
X953_18255	ENOG4105C8U	phosphate abc transporter
X953_18260	ENOG4105E2Z	phosphate ABC transporter (Permease
X953_18265	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
X953_18275	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
X953_18295	ENOG4108QY0	Membrane
X953_18310	ENOG4107RCC	Major Facilitator Superfamily
X953_18330	ENOG4105D7K	pfkb domain protein
X953_18350	ENOG4105C5Y	PTS System
X953_18355	ENOG410606W	general stress protein
X953_18360	ENOG4108RVA	ribokinase
X953_18375	ENOG4105ETE	Transcriptional regulator (LacI family
X953_18380	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
X953_18385	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
X953_18390	ENOG4107T2D	Phosphoribosylaminoimidazolesuccinocarboxamide synthase
X953_18395	ENOG4108UVJ	appr-1-p processing domain protein
X953_18420	ENOG4108S4H	thioesterase Superfamily protein
X953_18445	ENOG4105CMU	LysR family (Transcriptional regulator
X953_18450	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
X953_18455	ENOG4105E0C	molybdate abc transporter
X953_18460	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
X953_18475	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
X953_18485	ENOG4105CID	antiterminator
X953_18515	ENOG4108KF3	Electron transport protein SCO1 SenC
X953_18520	ENOG4105MVE	transcriptional regulator
X953_18535	ENOG4107QIV	Cytochrome c biogenesis protein
X953_18540	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
X953_18545	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
X953_18550	ENOG4105EB3	Histidine kinase
X953_18555	ENOG4107G87	m6 family metalloprotease domain protein
X953_18560	ENOG41085GJ	domain protein
X953_18565	ENOG41087NI	Sulfite exporter TauE/SafE
X953_18570	ENOG4105VFE	sira family
X953_18575	ENOG4107TPS	domain protein
X953_18580	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
X953_18585	ENOG4105VFE	sira family
X953_18590	ENOG41085GJ	domain protein
X953_18595	ENOG4105HF9	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
X953_18600	ENOG4105XTG	Pfam:DUF156
X953_18610	ENOG4108JU6	CBS domain protein
X953_18620	ENOG41069DP	small acid-soluble spore protein
X953_18630	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
X953_18640	ENOG4107TPS	domain protein
X953_18660	ENOG4105ED1	spovr family
X953_18670	ENOG4106AKX	UPF0229 protein
X953_18675	ENOG4105C1G	acyl-Coa dehydrogenase
X953_18680	ENOG4105E39	Enoyl-CoA hydratase
X953_18685	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
X953_18690	ENOG4105CEY	Amp-dependent synthetase and ligase
X953_18695	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
X953_18700	ENOG4108N5B	2-phosphosulfolactate phosphatase
X953_18715	ENOG4108IG5	Transcriptional regulator
X953_18720	ENOG4105CHR	reductase
X953_18725	ENOG4105C1G	acyl-Coa dehydrogenase
X953_18735	ENOG4105CYN	Serine protein kinase
X953_18755	ENOG4105NI8	Cytosine-specific methyltransferase
X953_19000	ENOG4105CYN	Serine protein kinase
X953_19025	ENOG4108UB7	
X953_19040	ENOG4105CAY	ferredoxin--nadp reductase
X953_19045	ENOG4105E0A	ABC, transporter
X953_19055	ENOG4105DQ5	transport system permease protein
X953_19060	ENOG4105EHG	Permease protein
X953_19080	ENOG4105CVG	Homoserine O-transsuccinylase
X953_19090	ENOG4105CK2	sodium dicarboxylate symporter
X953_19095	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
X953_19110	ENOG4105DXB	Major Facilitator superfamily
X953_19115	ENOG4105W87	Cbs domain
X953_19120	ENOG41061AU	MarR family Transcriptional regulator
X953_19130	ENOG4105E98	transcriptional regulator DeoR family
X953_19135	ENOG4105DE4	1-phosphofructokinase
X953_19140	ENOG4105DM4	PTS System
X953_19160	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
X953_19195	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
X953_19205	ENOG4105CYC	Transferase
X953_19215	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
X953_19230	ENOG4105CHR	reductase
X953_19240	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
X953_19245	ENOG4108M8H	domain protein
X953_19255	ENOG4107SNB	ankyrin repeat protein YahD
X953_19265	ENOG4105DJ2	Major Facilitator Superfamily
X953_19275	ENOG4105CHR	reductase
X953_19280	ENOG4105TRT	Transcriptional regulator
X953_19295	ENOG4105C26	Dehydrogenase
X953_19330	ENOG4105DZR	Type I site-specific deoxyribonuclease
X953_19355	ENOG4105W5Q	DNA repair protein (RadC
X953_19400	ENOG4105EMD	TRANSCRIPTIONal
X953_19405	ENOG4105F8D	glycoside hydrolase family 4
X953_19415	ENOG4105CK1	PTS System
X953_19420	ENOG410901P	UPF0249 protein
X953_19425	ENOG4105VCP	PTS System
X953_19430	ENOG4105EHZ	conserved protein UCP016719
X953_19435	ENOG4105KVH	Transcriptional regulator
X953_19455	ENOG4105S7S	phosphonate abc transporter
X953_19465	ENOG4105D5T	phosphonate abc transporter
X953_19475	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
X953_19485	ENOG4105CHR	reductase
X953_19500	ENOG4108VKI	Cell wall hydrolase
X953_19515	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
X953_19540	ENOG4105DMF	Dehydrogenase
X953_19560	ENOG4105BZU	Histidine kinase
X953_19590	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
X953_19600	ENOG4105BZ1	(ABC) transporter
X953_19610	ENOG4105C0H	protease
X953_19615	ENOG4105Q2H	domain protein
X953_19630	ENOG4105BZU	Histidine kinase
X953_19635	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
X953_19645	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
X953_19650	ENOG4105CDU	Replicative dna helicase
X953_19655	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
X953_19660	ENOG4105BZR	domain protein
X953_19665	ENOG4108XMW	Membrane
X953_19675	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
X953_19680	ENOG4108UUM	single-stranded DNA-binding protein
X953_19685	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
X953_19690	ENOG4105C3G	gtp-binding protein
X953_19695	ENOG4105VDK	protein, conserved in bacteria
X953_19700	ENOG4105D8X	mechanosensitive ion channel
X953_19710	ENOG4108ZDA	Sporulation protein YyaC
X953_19720	ENOG4105C9B	Cysteine desulfurase
X953_19725	ENOG4105FA0	parb-like partition protein
X953_19730	ENOG4107QJE	Chromosome Partitioning Protein
X953_19740	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
X953_19745	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
X953_19750	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
X953_19755	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
X953_19765	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
X953_19770	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
X953_19775	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)