locus-tag	class	description
VITFI_CDS0004	ENOG4105DH7	May be involved in recombination (By similarity)
VITFI_CDS0016	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
VITFI_CDS0020	ENOG4105ED1	spovr family
VITFI_CDS0021	ENOG4106AKX	UPF0229 protein
VITFI_CDS0022	ENOG4105CYN	Serine protein kinase
VITFI_CDS0024	ENOG4105FA0	parb-like partition protein
VITFI_CDS0026	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
VITFI_CDS0027	ENOG4107QJE	Chromosome Partitioning Protein
VITFI_CDS0028	ENOG4108NIW	Leucine export protein LeuE
VITFI_CDS0029	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
VITFI_CDS0030	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
VITFI_CDS0039	ENOG4105VJY	transcriptional regulator
VITFI_CDS0041	ENOG4108SDH	ABC, transporter
VITFI_CDS0042	ENOG4105CJ1	ABC, transporter
VITFI_CDS0043	ENOG4108HGY	Proline imino-peptidase
VITFI_CDS0045	ENOG4108K3A	Glutathione S-transferase
VITFI_CDS0046	ENOG4105EUB	pirin domain protein
VITFI_CDS0051	ENOG4108I0Y	(ABC) transporter
VITFI_CDS0053	ENOG4105DSE	periplasmic solute binding protein
VITFI_CDS0054	ENOG4105CC5	ABC transporter
VITFI_CDS0055	ENOG4105DIK	(ABC) transporter
VITFI_CDS0057	ENOG4105D3G	Pseudouridine synthase
VITFI_CDS0060	ENOG410620I	Diguanylate cyclase
VITFI_CDS0061	ENOG4105BZU	Histidine kinase
VITFI_CDS0062	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
VITFI_CDS0065	ENOG4105C3R	Methionine synthase
VITFI_CDS0068	ENOG4105C3R	Methionine synthase
VITFI_CDS0070	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
VITFI_CDS0071	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
VITFI_CDS0072	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
VITFI_CDS0072	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
VITFI_CDS0073	ENOG4105VG0	50S ribosomal protein l34
VITFI_CDS0074	ENOG4105X5M	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
VITFI_CDS0075	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
VITFI_CDS0076	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
VITFI_CDS0077	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
VITFI_CDS0079	ENOG4105E6M	Sulphatase-modifying factor protein
VITFI_CDS0081	ENOG4105VT3	DNA binding domain protein, excisionase family
VITFI_CDS0082	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
VITFI_CDS0091	ENOG4105KPY	Small multidrug resistance protein
VITFI_CDS0092	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
VITFI_CDS0107	ENOG4105EFV	Major head subunit
VITFI_CDS0113	ENOG4105QIB	mu-like prophage Flumu protein gp29
VITFI_CDS0114	ENOG4105CF2	Mu-like prophage FluMu protein GP28
VITFI_CDS0128	ENOG4105DH7	May be involved in recombination (By similarity)
VITFI_CDS0138	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
VITFI_CDS0139	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
VITFI_CDS0146	ENOG4105UIB	(ABC) transporter
VITFI_CDS0147	ENOG4105C2J	ABC transporter
VITFI_CDS0148	ENOG4107QUY	Guanine deaminase
VITFI_CDS0151	ENOG4105C7W	Xanthine dehydrogenase
VITFI_CDS0153	ENOG4107TSN	permease
VITFI_CDS0159	ENOG4108IV0	ABC, transporter
VITFI_CDS0160	ENOG4105C0Z	ABC transporter
VITFI_CDS0161	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
VITFI_CDS0162	ENOG4105C32	Amino acid ABC transporter (Permease)
VITFI_CDS0163	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
VITFI_CDS0166	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
VITFI_CDS0167	ENOG4105BZU	Histidine kinase
VITFI_CDS0168	ENOG4105DH7	May be involved in recombination (By similarity)
VITFI_CDS0169	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
VITFI_CDS0171	ENOG4105DR5	peptidase
VITFI_CDS0173	ENOG4105KB2	stringent starvation protein b
VITFI_CDS0174	ENOG4107MKT	Stringent starvation protein a
VITFI_CDS0175	ENOG4105EIX	cytochrome c1
VITFI_CDS0176	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
VITFI_CDS0177	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
VITFI_CDS0178	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
VITFI_CDS0179	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
VITFI_CDS0180	ENOG4107QNR	UPF0135 protein
VITFI_CDS0181	ENOG4105C0H	protease
VITFI_CDS0182	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
VITFI_CDS0183	ENOG4107Z6S	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
VITFI_CDS0184	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
VITFI_CDS0185	ENOG4107YU2	histidine triad (hIT) protein
VITFI_CDS0186	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
VITFI_CDS0187	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
VITFI_CDS0189	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
VITFI_CDS0191	ENOG4105CAS	nag kinase
VITFI_CDS0192	ENOG4105DZG	Dehydrogenase
VITFI_CDS0202	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
VITFI_CDS0203	ENOG4105CX6	glutaminyL-tRNA synthetase
VITFI_CDS0206	ENOG4105CK2	sodium dicarboxylate symporter
VITFI_CDS0208	ENOG4105KCK	Peptidoglycan-associated lipoprotein
VITFI_CDS0210	ENOG4107QJE	Chromosome Partitioning Protein
VITFI_CDS0211	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
VITFI_CDS0212	ENOG4107QMS	site-determining protein
VITFI_CDS0213	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
VITFI_CDS0214	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
VITFI_CDS0215	ENOG4105CKW	Inner membrane protein yedI
VITFI_CDS0217	ENOG4105NPQ	Pfam:DUF403
VITFI_CDS0224	ENOG4108EC8	DNA internalization-related competence protein ComEC
VITFI_CDS0230	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
VITFI_CDS0235	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
VITFI_CDS0238	ENOG4105DHP	deoxycytidine triphosphate deaminase
VITFI_CDS0244	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
VITFI_CDS0246	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
VITFI_CDS0247	ENOG4105C1A	potassium transporter peripheral membrane
VITFI_CDS0249	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
VITFI_CDS0253	ENOG4105C22	threonyL-tRNA synthetase
VITFI_CDS0254	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
VITFI_CDS0255	ENOG4105VJV	50s ribosomal protein L35
VITFI_CDS0256	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
VITFI_CDS0257	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
VITFI_CDS0258	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
VITFI_CDS0259	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
VITFI_CDS0263	ENOG4105BZU	Histidine kinase
VITFI_CDS0264	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
VITFI_CDS0270	ENOG4107QP8	phosphohexose isomerase
VITFI_CDS0271	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
VITFI_CDS0272	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
VITFI_CDS0273	ENOG4105CHC	glucokinase (EC 2.7.1.2)
VITFI_CDS0276	ENOG410903C	(LipO)protein
VITFI_CDS0277	ENOG4107PE3	Mammalian cell entry related domain protein
VITFI_CDS0278	ENOG4105CY3	ABC transporter, permease
VITFI_CDS0279	ENOG4105DHJ	ABC, transporter
VITFI_CDS0283	ENOG4105D49	3-dehydroquinate synthase
VITFI_CDS0284	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
VITFI_CDS0286	ENOG4105E4G	Type IV pilus
VITFI_CDS0291	ENOG4108JQC	penicillin-binding protein 1A
VITFI_CDS0292	ENOG4105XQ6	frataxin-like protein
VITFI_CDS0295	ENOG4105CFP	Peptidase U32
VITFI_CDS0300	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
VITFI_CDS0301	ENOG4105C26	Dehydrogenase
VITFI_CDS0305	ENOG4105CJB	Exodeoxyribonuclease I
VITFI_CDS0308	ENOG4108JB9	formate dehydrogenase
VITFI_CDS0313	ENOG4108JU3	Alkyl hydroperoxide reductase
VITFI_CDS0316	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
VITFI_CDS0318	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
VITFI_CDS0322	ENOG4108J2R	molybdopterin oxidoreductase
VITFI_CDS0327	ENOG4105CH2	amidohydrolase
VITFI_CDS0328	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
VITFI_CDS0329	ENOG4105CV1	Transketolase (EC 2.2.1.1)
VITFI_CDS0331	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
VITFI_CDS0333	ENOG4108S0S	Nucleotidyl transferase
VITFI_CDS0336	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
VITFI_CDS0337	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
VITFI_CDS0339	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
VITFI_CDS0340	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
VITFI_CDS0341	ENOG4105MJ2	Competence protein
VITFI_CDS0342	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
VITFI_CDS0344	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VITFI_CDS0346	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
VITFI_CDS0347	ENOG4108JJ6	Type I secretion system ATPase
VITFI_CDS0348	ENOG4105E6M	Sulphatase-modifying factor protein
VITFI_CDS0350	ENOG4105E39	Enoyl-CoA hydratase
VITFI_CDS0368	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
VITFI_CDS0369	ENOG4105BZU	Histidine kinase
VITFI_CDS0372	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
VITFI_CDS0373	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
VITFI_CDS0374	ENOG4108MG3	formate dehydrogenase
VITFI_CDS0375	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
VITFI_CDS0376	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
VITFI_CDS0379	ENOG4105BZU	Histidine kinase
VITFI_CDS0380	ENOG4107Z1W	Fructose transport system kinase
VITFI_CDS0382	ENOG410624X	efflux transporter, rnd family, mfp subunit
VITFI_CDS0384	ENOG4108UQY	Iron-storage protein
VITFI_CDS0387	ENOG4105C2M	dna polymerase I
VITFI_CDS0388	ENOG4105CUV	Homoserine Kinase
VITFI_CDS0390	ENOG4105BZU	Histidine kinase
VITFI_CDS0391	ENOG4106TD9	Diguanylate cyclase
VITFI_CDS0392	ENOG4105C4R	Atp-dependent dna helicase
VITFI_CDS0393	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
VITFI_CDS0395	ENOG4105DTT	CRISPR-associated helicase, cas3
VITFI_CDS0401	ENOG41060M0	Crispr-associated protein, cse4 family
VITFI_CDS0404	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
VITFI_CDS0405	ENOG4105PWE	CRISPR-associated protein cas2
VITFI_CDS0411	ENOG4105SG9	biopolymer transport protein, ExbD
VITFI_CDS0418	ENOG4105C01	Dihydroxy-acid dehydratase
VITFI_CDS0419	ENOG4108UHU	Aldolase
VITFI_CDS0423	ENOG4108TEB	UPF0114 protein
VITFI_CDS0425	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
VITFI_CDS0426	ENOG4105D82	Glutamate dehydrogenase
VITFI_CDS0427	ENOG4105II7	pyrroline-5-carboxylate reductase
VITFI_CDS0428	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
VITFI_CDS0429	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
VITFI_CDS0431	ENOG4105D3Q	Sugar transferase
VITFI_CDS0433	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
VITFI_CDS0436	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
VITFI_CDS0438	ENOG4105C1J	atp-dependent rna helicase
VITFI_CDS0439	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
VITFI_CDS0440	ENOG4108UHJ	MAF-like protein
VITFI_CDS0441	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
VITFI_CDS0442	ENOG4105VGS	50s ribosomal protein l32
VITFI_CDS0443	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
VITFI_CDS0444	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
VITFI_CDS0445	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
VITFI_CDS0446	ENOG4105CHR	reductase
VITFI_CDS0447	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
VITFI_CDS0448	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
VITFI_CDS0449	ENOG4105EMN	RNA polymerase sigma factor
VITFI_CDS0452	ENOG4105C0H	protease
VITFI_CDS0453	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
VITFI_CDS0454	ENOG4105C3F	Signal peptidase i
VITFI_CDS0456	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
VITFI_CDS0457	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
VITFI_CDS0458	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
VITFI_CDS0459	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
VITFI_CDS0460	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
VITFI_CDS0463	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
VITFI_CDS0464	ENOG4105C03	ribonuclease
VITFI_CDS0465	ENOG4105EI2	Pseudouridine synthase
VITFI_CDS0468	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
VITFI_CDS0469	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
VITFI_CDS0470	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
VITFI_CDS0471	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
VITFI_CDS0472	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
VITFI_CDS0473	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
VITFI_CDS0474	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
VITFI_CDS0476	ENOG4105CRE	cytochrome C
VITFI_CDS0478	ENOG4106RE7	Cytochrome
VITFI_CDS0479	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
VITFI_CDS0481	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
VITFI_CDS0482	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
VITFI_CDS0483	ENOG4105CRK	lysyL-tRNA synthetase
VITFI_CDS0485	ENOG4107R5Z	Oxidoreductase domain protein
VITFI_CDS0486	ENOG4105J5G	Transferase hexapeptide repeat containing protein
VITFI_CDS0489	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
VITFI_CDS0490	ENOG4108UW5	maltose o-acetyltransferase
VITFI_CDS0491	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
VITFI_CDS0496	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
VITFI_CDS0497	ENOG4105D3Q	Sugar transferase
VITFI_CDS0498	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
VITFI_CDS0499	ENOG4105BZS	acriflavin resistance protein
VITFI_CDS0500	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
VITFI_CDS0501	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
VITFI_CDS0503	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
VITFI_CDS0504	ENOG4108XG2	Histidine kinase
VITFI_CDS0505	ENOG4105WH1	Two component transcriptional regulator luxr family
VITFI_CDS0506	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
VITFI_CDS0507	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
VITFI_CDS0508	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
VITFI_CDS0509	ENOG4105CPF	Cell wall formation (By similarity)
VITFI_CDS0510	ENOG4105DFU	Cell wall formation (By similarity)
VITFI_CDS0511	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
VITFI_CDS0512	ENOG4105CNI	cell division protein FtsW
VITFI_CDS0513	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
VITFI_CDS0514	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
VITFI_CDS0515	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
VITFI_CDS0516	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
VITFI_CDS0519	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
VITFI_CDS0520	ENOG4105C2C	drug resistance transporter, Bcr CflA
VITFI_CDS0522	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
VITFI_CDS0523	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
VITFI_CDS0524	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
VITFI_CDS0525	ENOG4105DSJ	YicC domain protein
VITFI_CDS0527	ENOG4108ZF3	Phosphatase
VITFI_CDS0528	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
VITFI_CDS0529	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
VITFI_CDS0531	ENOG4105CSA	Coproporphyrinogen iii oxidase
VITFI_CDS0534	ENOG4105C98	muts2 protein
VITFI_CDS0536	ENOG4108R6K	riboflavin synthase, subunit alpha
VITFI_CDS0537	ENOG4105W5Q	DNA repair protein (RadC
VITFI_CDS0538	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
VITFI_CDS0539	ENOG4105C8U	phosphate abc transporter
VITFI_CDS0540	ENOG4105F38	ABC transporter, permease
VITFI_CDS0542	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
VITFI_CDS0543	ENOG410633P	Hydantoin racemase
VITFI_CDS0544	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
VITFI_CDS0545	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
VITFI_CDS0546	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
VITFI_CDS0547	ENOG4105C0D	helicase
VITFI_CDS0548	ENOG4105DFP	Integrase
VITFI_CDS0563	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VITFI_CDS0564	ENOG4105ES5	Histidine kinase
VITFI_CDS0566	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
VITFI_CDS0570	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
VITFI_CDS0571	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
VITFI_CDS0572	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
VITFI_CDS0574	ENOG4105C9U	ATP-dependent DNA helicase RecQ
VITFI_CDS0581	ENOG4105U82	Ferredoxin
VITFI_CDS0582	ENOG4105CY9	nitrogenase molybdenum-iron protein beta chain
VITFI_CDS0583	ENOG4105D0B	Nitrogenase protein alpha chain
VITFI_CDS0584	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
VITFI_CDS0587	ENOG4107RP9	extracellular solute-binding protein, family 3
VITFI_CDS0593	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
VITFI_CDS0595	ENOG41080Z8	PHOSPHOCARRIER protein
VITFI_CDS0597	ENOG4108JNI	Alpha beta hydrolase
VITFI_CDS0598	ENOG4107QX9	Thiol disulfide interChange protein
VITFI_CDS0600	ENOG4105W2Z	cytochrome C, class I
VITFI_CDS0601	ENOG4105D2N	Aldolase
VITFI_CDS0603	ENOG4105CV1	Transketolase (EC 2.2.1.1)
VITFI_CDS0604	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
VITFI_CDS0605	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
VITFI_CDS0606	ENOG4106F1P	AAA ATPase, central domain protein
VITFI_CDS0609	ENOG4108QUU	Morphogenesis Protein
VITFI_CDS0611	ENOG4105CF2	Mu-like prophage FluMu protein GP28
VITFI_CDS0640	ENOG4105DH7	May be involved in recombination (By similarity)
VITFI_CDS0654	ENOG4105CF2	Mu-like prophage FluMu protein GP28
VITFI_CDS0655	ENOG4105QIB	mu-like prophage Flumu protein gp29
VITFI_CDS0661	ENOG4105EFV	Major head subunit
VITFI_CDS0676	ENOG4105MIR	Phenylalanine 4-monooxygenase
VITFI_CDS0678	ENOG4105DUM	transcriptional regulator, lysR family
VITFI_CDS0680	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
VITFI_CDS0683	ENOG4107T8Q	Glycosyl transferase (Group 1
VITFI_CDS0686	ENOG4105D7W	serine acetyltransferase
VITFI_CDS0688	ENOG4107RA4	Glycosyl transferase (Group 1
VITFI_CDS0693	ENOG4107YJ4	chain length determinant protein
VITFI_CDS0700	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
VITFI_CDS0701	ENOG41082RQ	UPF0102 protein
VITFI_CDS0702	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
VITFI_CDS0703	ENOG4105K3G	Periplasmic Protein
VITFI_CDS0704	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
VITFI_CDS0705	ENOG4105CZX	twitching motility protein
VITFI_CDS0706	ENOG4105CZX	twitching motility protein
VITFI_CDS0707	ENOG4105DFA	alanine racemase domain protein
VITFI_CDS0708	ENOG4105C2W	permease
VITFI_CDS0712	ENOG41063Z6	transcriptional regulator, lysR family
VITFI_CDS0714	ENOG4105DU1	integral membrane protein, terc
VITFI_CDS0719	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
VITFI_CDS0720	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
VITFI_CDS0724	ENOG4108J59	Extracellular solute-binding protein, family 5
VITFI_CDS0727	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
VITFI_CDS0729	ENOG4105W8H	transhydrogenase (subunit alpha
VITFI_CDS0730	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
VITFI_CDS0733	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
VITFI_CDS0736	ENOG4105ERG	peptidase m48, ste24p
VITFI_CDS0737	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
VITFI_CDS0738	ENOG4108YSG	O-Antigen polymerase
VITFI_CDS0743	ENOG4108UW8	fha domain-containing protein
VITFI_CDS0744	ENOG4108ZF3	Phosphatase
VITFI_CDS0745	ENOG4108ZCF	integral membrane protein
VITFI_CDS0746	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
VITFI_CDS0747	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
VITFI_CDS0749	ENOG4108004	Modulates RecA activity (By similarity)
VITFI_CDS0750	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
VITFI_CDS0752	ENOG4105DHQ	Histidine kinase
VITFI_CDS0753	ENOG4105CNI	cell division protein FtsW
VITFI_CDS0754	ENOG4105CJN	penicillin-binding protein
VITFI_CDS0757	ENOG4105DFF	Rod shape-determining protein mreb
VITFI_CDS0758	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
VITFI_CDS0759	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
VITFI_CDS0760	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
VITFI_CDS0761	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
VITFI_CDS0762	ENOG4105CGK	Exodeoxyribonuclease III
VITFI_CDS0763	ENOG4105C5X	domain protein
VITFI_CDS0765	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
VITFI_CDS0767	ENOG4105EYM	Major Facilitator superfamily
VITFI_CDS0773	ENOG4105NWN	ApaG protein
VITFI_CDS0775	ENOG4105DJV	ribulose-phosphate 3-epimerase
VITFI_CDS0776	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
VITFI_CDS0778	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
VITFI_CDS0780	ENOG4105DDQ	anthranilate synthase
VITFI_CDS0782	ENOG4107QYG	anthranilate phosphoribosyltransferase
VITFI_CDS0783	ENOG4105DK0	Indole-3-glycerol phosphate synthase
VITFI_CDS0784	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
VITFI_CDS0786	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
VITFI_CDS0789	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
VITFI_CDS0790	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
VITFI_CDS0792	ENOG4108VZM	50s ribosomal protein L10
VITFI_CDS0793	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
VITFI_CDS0795	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
VITFI_CDS0796	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
VITFI_CDS0797	ENOG4105DWF	phosphomethylpyrimidine kinase
VITFI_CDS0798	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
VITFI_CDS0801	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
VITFI_CDS0804	ENOG4105CE1	Ferrous iron transport protein b
VITFI_CDS0806	ENOG4105BZU	Histidine kinase
VITFI_CDS0807	ENOG4108RPX	mosc domain containing protein
VITFI_CDS0809	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
VITFI_CDS0811	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
VITFI_CDS0814	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
VITFI_CDS0815	ENOG4105D6S	protein involved in catabolism of external DNA
VITFI_CDS0819	ENOG4105BZU	Histidine kinase
VITFI_CDS0821	ENOG4105EXG	Transcriptional regulator
VITFI_CDS0822	ENOG4105C26	Dehydrogenase
VITFI_CDS0825	ENOG410620I	Diguanylate cyclase
VITFI_CDS0826	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
VITFI_CDS0829	ENOG4105D1S	lipid A biosynthesis
VITFI_CDS0830	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
VITFI_CDS0832	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
VITFI_CDS0835	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
VITFI_CDS0839	ENOG4107S7U	Sulfide dehydrogenase
VITFI_CDS0844	ENOG4105VPX	protein, conserved in bacteria
VITFI_CDS0849	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
VITFI_CDS0850	ENOG4105C9A	Phoh family
VITFI_CDS0851	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
VITFI_CDS0859	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
VITFI_CDS0861	ENOG4105C8Q	Methyl-accepting chemotaxis
VITFI_CDS0862	ENOG4105CBS	Chea signal transduction histidine kinase
VITFI_CDS0867	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
VITFI_CDS0868	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
VITFI_CDS0870	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
VITFI_CDS0886	ENOG4105E7A	Glutamine amidotransferase
VITFI_CDS0890	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
VITFI_CDS0892	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
VITFI_CDS0893	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
VITFI_CDS0895	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
VITFI_CDS0902	ENOG4105W2Z	cytochrome C, class I
VITFI_CDS0903	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
VITFI_CDS0906	ENOG4108JQC	penicillin-binding protein 1A
VITFI_CDS0907	ENOG4108U78	Glutathione S-transferase
VITFI_CDS0908	ENOG4107QTF	adenylosuccinate lyase
VITFI_CDS0909	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
VITFI_CDS0910	ENOG410829K	Lysine exporter protein (Lyse ygga)
VITFI_CDS0912	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
VITFI_CDS0916	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
VITFI_CDS0920	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
VITFI_CDS0921	ENOG4105C4R	Atp-dependent dna helicase
VITFI_CDS0922	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
VITFI_CDS0923	ENOG4108XM1	transcriptional regulator AsnC family
VITFI_CDS0925	ENOG4107TVJ	,Oxidoreductase FAD NAD(P)-binding
VITFI_CDS0926	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
VITFI_CDS0929	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
VITFI_CDS0930	ENOG4105DWV	Homoserine O-trans-acetylase
VITFI_CDS0933	ENOG4105CT7	inner membrane cred family protein
VITFI_CDS0934	ENOG4105EB3	Histidine kinase
VITFI_CDS0935	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
VITFI_CDS0936	ENOG4105VFU	Rna-binding protein
VITFI_CDS0938	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
VITFI_CDS0939	ENOG4105C2X	Arabinose 5-phosphate isomerase
VITFI_CDS0943	ENOG4105CHR	reductase
VITFI_CDS0946	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
VITFI_CDS0951	ENOG4105EKQ	RNA-directed DNA polymerase
VITFI_CDS0955	ENOG4105PNM	synthesis protein
VITFI_CDS0957	ENOG4105EJQ	L-serine dehydratase
VITFI_CDS0958	ENOG4105E6M	Sulphatase-modifying factor protein
VITFI_CDS0959	ENOG4105C1V	Peptidase, M16
VITFI_CDS0961	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
VITFI_CDS0962	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VITFI_CDS0963	ENOG4108IUZ	ABC transporter
VITFI_CDS0964	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
VITFI_CDS0966	ENOG4105C75	arginyL-tRNA synthetase
VITFI_CDS0970	ENOG4105EJC	lysr family transcriptional regulator
VITFI_CDS0972	ENOG4107QP3	malate synthase g
VITFI_CDS0973	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
VITFI_CDS0975	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
VITFI_CDS0976	ENOG4105DR4	Methyltransferase
VITFI_CDS0984	ENOG4105W2Z	cytochrome C, class I
VITFI_CDS0985	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
VITFI_CDS0990	ENOG4105C5Q	Transcriptional regulator
VITFI_CDS0992	ENOG4105CM2	brancheD-chain amino acid aminotransferase
VITFI_CDS0995	ENOG4108MTB	glycosyl transferase family
VITFI_CDS0996	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
VITFI_CDS0998	ENOG4108IFG	nitrite reductase, (NAD(P)H)
VITFI_CDS0999	ENOG4105D9P	serine threonine protein kinase
VITFI_CDS1002	ENOG4105D6J	arsenicaL-resistance protein
VITFI_CDS1003	ENOG4108UXE	Protein tyrosine phosphatase
VITFI_CDS1004	ENOG4107WAU	Protein tyrosine phosphatase
VITFI_CDS1015	ENOG4105PGM	cation diffusion facilitator family transporter
VITFI_CDS1016	ENOG4105D9G	High-affinity
VITFI_CDS1019	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
VITFI_CDS1020	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
VITFI_CDS1021	ENOG4108Z43	UPF0250 protein
VITFI_CDS1023	ENOG4105DZ1	carboxypeptidase
VITFI_CDS1025	ENOG4105NZG	Ferredoxin
VITFI_CDS1028	ENOG4105D52	delta-aminolevulinic acid dehydratase
VITFI_CDS1029	ENOG4105D7N	magnesium and cobalt transport protein CorA
VITFI_CDS1034	ENOG4107QX9	Thiol disulfide interChange protein
VITFI_CDS1037	ENOG4107S7U	Sulfide dehydrogenase
VITFI_CDS1040	ENOG4105CA0	peroxidase
VITFI_CDS1041	ENOG4105DUM	transcriptional regulator, lysR family
VITFI_CDS1042	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
VITFI_CDS1043	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
VITFI_CDS1057	ENOG4105EFV	Major head subunit
VITFI_CDS1064	ENOG4105QIB	mu-like prophage Flumu protein gp29
VITFI_CDS1065	ENOG4105CF2	Mu-like prophage FluMu protein GP28
VITFI_CDS1079	ENOG4105DH7	May be involved in recombination (By similarity)
VITFI_CDS1090	ENOG4105DIJ	Phosphoethanolamine transferase
VITFI_CDS1091	ENOG4105E12	capsule polysaccharide
VITFI_CDS1092	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
VITFI_CDS1093	ENOG4105C11	sulfate adenylyltransferase), subunit 2
VITFI_CDS1099	ENOG4105K6T	rare lipoprotein A
VITFI_CDS1102	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
VITFI_CDS1103	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
VITFI_CDS1104	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
VITFI_CDS1105	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
VITFI_CDS1106	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
VITFI_CDS1107	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
VITFI_CDS1108	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
VITFI_CDS1109	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
VITFI_CDS1113	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
VITFI_CDS1114	ENOG4105C25	Primosomal protein n'
VITFI_CDS1115	ENOG4107QN1	sodium solute
VITFI_CDS1116	ENOG41062QD	Membrane
VITFI_CDS1117	ENOG4105C4R	Atp-dependent dna helicase
VITFI_CDS1119	ENOG4105DFH	Transport of potassium into the cell (By similarity)
VITFI_CDS1122	ENOG4105BZU	Histidine kinase
VITFI_CDS1123	ENOG4108YZA	Nitrogen regulatory protein pii
VITFI_CDS1124	ENOG4105C0P	Mg chelatase subunit ChlI
VITFI_CDS1125	ENOG4105EKQ	RNA-directed DNA polymerase
VITFI_CDS1126	ENOG4105C0P	Mg chelatase subunit ChlI
VITFI_CDS1130	ENOG41090SZ	ABC-2 type transporter
VITFI_CDS1133	ENOG4107V1M	polysaccharide export protein
VITFI_CDS1139	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
VITFI_CDS1140	ENOG4108WBT	adenosyltransferase
VITFI_CDS1142	ENOG4107YTP	response regulator receiver protein
VITFI_CDS1143	ENOG4105CBS	Chea signal transduction histidine kinase
VITFI_CDS1145	ENOG4105D7T	ABC transporter
VITFI_CDS1147	ENOG4105I5W	Transporter
VITFI_CDS1151	ENOG4105CEY	Amp-dependent synthetase and ligase
VITFI_CDS1152	ENOG4105C10	Electron transfer flavoprotein
VITFI_CDS1153	ENOG4105BZJ	Electron transfer flavoprotein
VITFI_CDS1154	ENOG4108Z7G	MaoC domain protein dehydratase
VITFI_CDS1155	ENOG4105CSU	acyl-Coa dehydrogenase
VITFI_CDS1156	ENOG4105CEY	Amp-dependent synthetase and ligase
VITFI_CDS1158	ENOG41065U4	response regulator
VITFI_CDS1159	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
VITFI_CDS1160	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
VITFI_CDS1161	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
VITFI_CDS1163	ENOG4105C0Z	ABC transporter
VITFI_CDS1164	ENOG4105C32	Amino acid ABC transporter (Permease)
VITFI_CDS1167	ENOG4108IV0	ABC, transporter
VITFI_CDS1168	ENOG4105DZS	Phenylacetate-CoA ligase
VITFI_CDS1170	ENOG4105CHU	acetyl-coa acetyltransferase
VITFI_CDS1171	ENOG4105C1G	acyl-Coa dehydrogenase
VITFI_CDS1172	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
VITFI_CDS1175	ENOG4105D5P	Methylmalonyl-coA mutase
VITFI_CDS1177	ENOG4105F04	LysR family Transcriptional regulator
VITFI_CDS1179	ENOG4105BZU	Histidine kinase
VITFI_CDS1182	ENOG4107RH7	Nicotinate phosphoribosyltransferase
VITFI_CDS1187	ENOG4107QX8	SPFH domain, Band 7 family protein
VITFI_CDS1189	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
VITFI_CDS1192	ENOG4108NIW	Leucine export protein LeuE
VITFI_CDS1199	ENOG4105D0A	hydroxylase
VITFI_CDS1201	ENOG4108ZXC	Two component transcriptional regulator, luxr family
VITFI_CDS1202	ENOG4105BZU	Histidine kinase
VITFI_CDS1203	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
VITFI_CDS1204	ENOG4108RA0	tripartite ATP-independent periplasmic transporter, DctQ component
VITFI_CDS1205	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
VITFI_CDS1206	ENOG4105C31	Tryptophanyl-tRNA synthetase
VITFI_CDS1207	ENOG4105DXC	membrane
VITFI_CDS1209	ENOG4105K64	Glycosyl transferase, family 2
VITFI_CDS1212	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
VITFI_CDS1214	ENOG4108VD1	dedA family
VITFI_CDS1215	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
VITFI_CDS1216	ENOG4105CQB	FAD linked oxidase domain protein
VITFI_CDS1218	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
VITFI_CDS1219	ENOG4105CGF	Aromatic amino acid aminotransferase
VITFI_CDS1221	ENOG4105VBA	Cytochrome
VITFI_CDS1224	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
VITFI_CDS1225	ENOG4105DHQ	Histidine kinase
VITFI_CDS1229	ENOG4108PQP	glycosyl transferase group 1
VITFI_CDS1230	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
VITFI_CDS1234	ENOG4105CEY	Amp-dependent synthetase and ligase
VITFI_CDS1235	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
VITFI_CDS1236	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
VITFI_CDS1237	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
VITFI_CDS1238	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
VITFI_CDS1239	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
VITFI_CDS1240	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
VITFI_CDS1241	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
VITFI_CDS1242	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
VITFI_CDS1243	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VITFI_CDS1244	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
VITFI_CDS1245	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
VITFI_CDS1246	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
VITFI_CDS1247	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
VITFI_CDS1248	ENOG41084PQ	50s ribosomal protein l29
VITFI_CDS1249	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
VITFI_CDS1252	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
VITFI_CDS1253	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
VITFI_CDS1254	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VITFI_CDS1255	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
VITFI_CDS1256	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
VITFI_CDS1257	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
VITFI_CDS1258	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
VITFI_CDS1259	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
VITFI_CDS1260	ENOG4105VPB	50S ribosomal protein L30
VITFI_CDS1261	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
VITFI_CDS1262	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
VITFI_CDS1264	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VITFI_CDS1265	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
VITFI_CDS1266	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
VITFI_CDS1267	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
VITFI_CDS1268	ENOG4108ZT0	50S ribosomal protein l17
VITFI_CDS1269	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
VITFI_CDS1270	ENOG4105VIE	preprotein translocase, subunit YajC
VITFI_CDS1271	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
VITFI_CDS1272	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
VITFI_CDS1274	ENOG4108RPN	Protein smg homolog
VITFI_CDS1275	ENOG4105C79	DNA protecting protein DprA
VITFI_CDS1277	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
VITFI_CDS1278	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
VITFI_CDS1279	ENOG4105D0M	Protease HtpX homolog
VITFI_CDS1282	ENOG4105BZA	Phosphoglycerate kinase
VITFI_CDS1283	ENOG4105C6K	Malic enzyme
VITFI_CDS1284	ENOG4105CA9	Pyruvate kinase
VITFI_CDS1285	ENOG4105D2N	Aldolase
VITFI_CDS1287	ENOG4105C8V	SAICAR synthetase
VITFI_CDS1290	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
VITFI_CDS1291	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
VITFI_CDS1292	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
VITFI_CDS1295	ENOG4105W3H	MtN3 and saliva related transmembrane protein
VITFI_CDS1296	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
VITFI_CDS1297	ENOG41072GX	Peptidase M22 Glycoprotease
VITFI_CDS1298	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
VITFI_CDS1305	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
VITFI_CDS1310	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
VITFI_CDS1314	ENOG4105NWF	RbsD or FucU transport
VITFI_CDS1315	ENOG4105C2J	ABC transporter
VITFI_CDS1316	ENOG4105CNN	ABC, transporter
VITFI_CDS1317	ENOG4107R5G	Periplasmic binding protein LacI transcriptional regulator
VITFI_CDS1325	ENOG4105RK9	auxin efflux carrier
VITFI_CDS1328	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
VITFI_CDS1332	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
VITFI_CDS1334	ENOG4105CSR	polyphosphate kinase 2
VITFI_CDS1335	ENOG4105CSR	polyphosphate kinase 2
VITFI_CDS1337	ENOG4105BZU	Histidine kinase
VITFI_CDS1338	ENOG4105BZU	Histidine kinase
VITFI_CDS1339	ENOG4108ZXC	Two component transcriptional regulator, luxr family
VITFI_CDS1342	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
VITFI_CDS1344	ENOG4105C0D	helicase
VITFI_CDS1345	ENOG4105DX0	Hemolysin A
VITFI_CDS1346	ENOG4105SYT	Methylenetetrahydrofolate reductase
VITFI_CDS1350	ENOG4105ETT	transcriptional Regulator, LysR family
VITFI_CDS1359	ENOG4105CPK	Glycosyl transferase (Group 1
VITFI_CDS1360	ENOG4107BJW	polysaccharide deacetylase
VITFI_CDS1365	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
VITFI_CDS1366	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
VITFI_CDS1374	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
VITFI_CDS1375	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
VITFI_CDS1376	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
VITFI_CDS1379	ENOG4108PVQ	transcriptional regulator
VITFI_CDS1392	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
VITFI_CDS1393	ENOG4105EU8	FAD linked oxidase domain protein
VITFI_CDS1394	ENOG4105CQB	FAD linked oxidase domain protein
VITFI_CDS1401	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
VITFI_CDS1404	ENOG4108UJD	30S ribosomal protein S9
VITFI_CDS1405	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
VITFI_CDS1409	ENOG4105CB5	ATP-dependent DNA helicase recG
VITFI_CDS1410	ENOG4108I5D	sulfate abc transporter
VITFI_CDS1412	ENOG4108IJ6	ABC transporter
VITFI_CDS1413	ENOG4106H3A	restriction
VITFI_CDS1414	ENOG4105CB5	ATP-dependent DNA helicase recG
VITFI_CDS1415	ENOG4105ESI	atpase involved in dna repair
VITFI_CDS1416	ENOG4105C1J	atp-dependent rna helicase
VITFI_CDS1418	ENOG4107R11	Transcriptional regulator
VITFI_CDS1420	ENOG4105F4R	Transcriptional regulator mode
VITFI_CDS1422	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
VITFI_CDS1423	ENOG4105DSU	hydrolase
VITFI_CDS1424	ENOG4107QUT	magnesium and cobalt transport protein CorA
VITFI_CDS1425	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
VITFI_CDS1426	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
VITFI_CDS1427	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
VITFI_CDS1428	ENOG41090R7	Ferric uptake
VITFI_CDS1429	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
VITFI_CDS1430	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
VITFI_CDS1432	ENOG4105SG9	biopolymer transport protein, ExbD
VITFI_CDS1433	ENOG4105C8T	Leucyl-tRNA synthetase
VITFI_CDS1436	ENOG4105CEV	competence damage-inducible protein
VITFI_CDS1437	ENOG4108ZAI	phosphatidylglycerophosphatase a
VITFI_CDS1438	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
VITFI_CDS1439	ENOG4105C1J	atp-dependent rna helicase
VITFI_CDS1445	ENOG4108ZXC	Two component transcriptional regulator, luxr family
VITFI_CDS1446	ENOG4105BZU	Histidine kinase
VITFI_CDS1447	ENOG4105C6K	Malic enzyme
VITFI_CDS1451	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
VITFI_CDS1452	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
VITFI_CDS1453	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
VITFI_CDS1454	ENOG4105EHM	Aminoglycoside phosphotransferase
VITFI_CDS1455	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
VITFI_CDS1457	ENOG4105E4C	Lytic transglycosylase catalytic
VITFI_CDS1459	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
VITFI_CDS1460	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
VITFI_CDS1461	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
VITFI_CDS1462	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
VITFI_CDS1463	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
VITFI_CDS1464	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
VITFI_CDS1465	ENOG4108JU5	Magnesium and cobalt efflux protein
VITFI_CDS1466	ENOG4105CKI	cobalamin synthesis protein
VITFI_CDS1467	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
VITFI_CDS1469	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
VITFI_CDS1470	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
VITFI_CDS1475	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
VITFI_CDS1477	ENOG4108V1T	peptidylprolyl cis-trans isomerase
VITFI_CDS1478	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
VITFI_CDS1479	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
VITFI_CDS1481	ENOG4105BZU	Histidine kinase
VITFI_CDS1483	ENOG4105C9U	ATP-dependent DNA helicase RecQ
VITFI_CDS1485	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
VITFI_CDS1489	ENOG4105D7Z	glutathione synthase
VITFI_CDS1495	ENOG4105C5H	ABC transporter
VITFI_CDS1500	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
VITFI_CDS1502	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
VITFI_CDS1505	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VITFI_CDS1506	ENOG4105CHU	acetyl-coa acetyltransferase
VITFI_CDS1516	ENOG4105DH7	May be involved in recombination (By similarity)
VITFI_CDS1530	ENOG4105CF2	Mu-like prophage FluMu protein GP28
VITFI_CDS1531	ENOG4105QIB	mu-like prophage Flumu protein gp29
VITFI_CDS1537	ENOG4105EFV	Major head subunit
VITFI_CDS1557	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
VITFI_CDS1558	ENOG4105CV6	ABC transporter, permease
VITFI_CDS1561	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
VITFI_CDS1563	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
VITFI_CDS1565	ENOG4105DTN	riboflavin biosynthesis protein ribF
VITFI_CDS1566	ENOG4105I08	Pseudouridine synthase
VITFI_CDS1568	ENOG4105CEY	Amp-dependent synthetase and ligase
VITFI_CDS1579	ENOG4107QR9	Iron-sulfur cluster binding protein
VITFI_CDS1580	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
VITFI_CDS1581	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
VITFI_CDS1582	ENOG41073TP	transcriptional regulator
VITFI_CDS1583	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
VITFI_CDS1585	ENOG4105D64	Mechanosensitive ion channel
VITFI_CDS1586	ENOG4105CGU	Enoyl-CoA hydratase
VITFI_CDS1587	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
VITFI_CDS1588	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
VITFI_CDS1596	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
VITFI_CDS1602	ENOG4105C32	Amino acid ABC transporter (Permease)
VITFI_CDS1604	ENOG4105C0Z	ABC transporter
VITFI_CDS1605	ENOG4108IV0	ABC, transporter
VITFI_CDS1606	ENOG4105CHU	acetyl-coa acetyltransferase
VITFI_CDS1607	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
VITFI_CDS1608	ENOG4105CHU	acetyl-coa acetyltransferase
VITFI_CDS1612	ENOG4105VZ9	UPF0235 protein
VITFI_CDS1616	ENOG4105CD5	CoA-binding domain protein
VITFI_CDS1619	ENOG4105E0F	Histidine kinase
VITFI_CDS1620	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
VITFI_CDS1622	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
VITFI_CDS1623	ENOG4105WD1	Membrane
VITFI_CDS1625	ENOG4105DMF	Dehydrogenase
VITFI_CDS1627	ENOG4105DUM	transcriptional regulator, lysR family
VITFI_CDS1629	ENOG4105C3J	Cysteine desulfurase
VITFI_CDS1630	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
VITFI_CDS1631	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
VITFI_CDS1632	ENOG4108Z4V	iron-sulfur cluster assembly
VITFI_CDS1633	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
VITFI_CDS1634	ENOG4108ZIT	Ferredoxin, 2FE-2S
VITFI_CDS1636	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
VITFI_CDS1637	ENOG410605C	May protect the nitrogenase Fe-Mo protein from oxidative damage (By similarity)
VITFI_CDS1638	ENOG4105BZJ	Electron transfer flavoprotein
VITFI_CDS1639	ENOG4105C10	Electron transfer flavoprotein
VITFI_CDS1641	ENOG41090P5	ferredoxin-like protein
VITFI_CDS1643	ENOG4105PUF	Ferredoxin, 2FE-2S
VITFI_CDS1644	ENOG4108JUA	Transcriptional regulator
VITFI_CDS1647	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
VITFI_CDS1648	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
VITFI_CDS1651	ENOG4108QWQ	LRV FeS4 cluster domain protein
VITFI_CDS1655	ENOG4105C3J	Cysteine desulfurase
VITFI_CDS1658	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
VITFI_CDS1663	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
VITFI_CDS1672	ENOG4105ND9	Nitrogenase-associated protein
VITFI_CDS1674	ENOG41065RQ	ADP-ribosylation crystallin J1
VITFI_CDS1675	ENOG4108K8Z	nad( )--dinitrogen-reductase ADP-d-ribosyltransferase
VITFI_CDS1676	ENOG4105C4R	Atp-dependent dna helicase
VITFI_CDS1680	ENOG41082UU	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
VITFI_CDS1682	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
VITFI_CDS1683	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
VITFI_CDS1684	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
VITFI_CDS1691	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
VITFI_CDS1692	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
VITFI_CDS1694	ENOG4107SC1	transglycosylase
VITFI_CDS1695	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
VITFI_CDS1697	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
VITFI_CDS1699	ENOG4105D05	Receptor
VITFI_CDS1700	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
VITFI_CDS1702	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
VITFI_CDS1703	ENOG4105D1F	ATP-binding protein
VITFI_CDS1705	ENOG4105EVZ	LysR family transcriptional regulator
VITFI_CDS1706	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
VITFI_CDS1707	ENOG4105EKE	dihydroorotase
VITFI_CDS1708	ENOG4105BZU	Histidine kinase
VITFI_CDS1710	ENOG4105K5B	UPF0225 protein
VITFI_CDS1711	ENOG4105DR9	pseudouridine synthase
VITFI_CDS1712	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
VITFI_CDS1714	ENOG4105I7R	Adenylate cyclase
VITFI_CDS1717	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
VITFI_CDS1723	ENOG4105CCT	upf0313 protein
VITFI_CDS1729	ENOG4105D06	uba thif-type nad fad binding protein
VITFI_CDS1730	ENOG4105CN1	protease
VITFI_CDS1731	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
VITFI_CDS1734	ENOG4105CHH	sulfate transporter
VITFI_CDS1735	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
VITFI_CDS1736	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
VITFI_CDS1737	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
VITFI_CDS1738	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
VITFI_CDS1739	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
VITFI_CDS1745	ENOG4108C33	Resolvase
VITFI_CDS1746	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
VITFI_CDS1748	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
VITFI_CDS1752	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
VITFI_CDS1754	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
VITFI_CDS1756	ENOG4105CQM	Urea amidohydrolase subunit alpha
VITFI_CDS1757	ENOG4105KI2	Urea amidohydrolase subunit beta
VITFI_CDS1758	ENOG4108YZ9	Urea amidohydrolase subunit gamma
VITFI_CDS1759	ENOG4105CG3	alpha amylase, catalytic region
VITFI_CDS1760	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
VITFI_CDS1762	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
VITFI_CDS1763	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
VITFI_CDS1764	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
VITFI_CDS1766	ENOG4108VAC	response regulator
VITFI_CDS1767	ENOG4108HRK	Histidine kinase
VITFI_CDS1773	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
VITFI_CDS1777	ENOG4105D7A	ATP-binding protein
VITFI_CDS1778	ENOG4105CDY	transcriptional regulatory protein
VITFI_CDS1779	ENOG4105C12	Phosphoribosylglycinamide synthetase
VITFI_CDS1780	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
VITFI_CDS1781	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
VITFI_CDS1782	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
VITFI_CDS1783	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
VITFI_CDS1788	ENOG4108Z03	MAF-like protein
VITFI_CDS1789	ENOG4105C03	ribonuclease
VITFI_CDS1790	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
VITFI_CDS1791	ENOG4105KCK	Peptidoglycan-associated lipoprotein
VITFI_CDS1793	ENOG4105CUZ	uba thif-type nad fad binding protein
VITFI_CDS1794	ENOG4105KUZ	arsenate reductase
VITFI_CDS1795	ENOG4105C9X	ppx gppa phosphatase
VITFI_CDS1797	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
VITFI_CDS1799	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
VITFI_CDS1800	ENOG4108K5P	(LipO)protein
VITFI_CDS1802	ENOG4108MN8	Membrane
VITFI_CDS1809	ENOG4108NIW	Leucine export protein LeuE
VITFI_CDS1810	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
VITFI_CDS1811	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
VITFI_CDS1814	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
VITFI_CDS1815	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
VITFI_CDS1816	ENOG4105EEI	dihydropteroate synthase
VITFI_CDS1817	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
VITFI_CDS1818	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
VITFI_CDS1819	ENOG4105C8U	phosphate abc transporter
VITFI_CDS1820	ENOG4105E2Z	phosphate ABC transporter (Permease
VITFI_CDS1821	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
VITFI_CDS1823	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
VITFI_CDS1824	ENOG4105BZU	Histidine kinase
VITFI_CDS1826	ENOG4105NRA	50s ribosomal protein l31 type b
VITFI_CDS1827	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
VITFI_CDS1829	ENOG4105K63	Thioredoxin
VITFI_CDS1831	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
VITFI_CDS1832	ENOG4105HDK	L-asparaginase
VITFI_CDS1833	ENOG4105C5H	ABC transporter
VITFI_CDS1834	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
VITFI_CDS1835	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
VITFI_CDS1836	ENOG4105CZX	twitching motility protein
VITFI_CDS1837	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
VITFI_CDS1839	ENOG4105CHM	Aminotransferase
VITFI_CDS1840	ENOG4105F0N	pyrophosphate phospho-hydrolase
VITFI_CDS1859	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VITFI_CDS1860	ENOG4105CUX	Signal transduction histidine kinase
VITFI_CDS1862	ENOG4105C5F	glutamine synthetase
VITFI_CDS1870	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
VITFI_CDS1871	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
VITFI_CDS1872	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
VITFI_CDS1873	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
VITFI_CDS1874	ENOG4109015	Biopolymer transport protein exbD tolR
VITFI_CDS1876	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
VITFI_CDS1877	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
VITFI_CDS1878	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
VITFI_CDS1879	ENOG4105E0F	Histidine kinase
VITFI_CDS1883	ENOG4105EYA	deoxyribonuclease
VITFI_CDS1884	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
VITFI_CDS1885	ENOG4107QHF	type ii secretion system protein e
VITFI_CDS1887	ENOG4105C59	p-type ATPase
VITFI_CDS1889	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
VITFI_CDS1895	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
VITFI_CDS1897	ENOG4105D4P	Coproporphyrinogen iii oxidase
VITFI_CDS1900	ENOG4105VEQ	Cold shock protein
VITFI_CDS1901	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
VITFI_CDS1902	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
VITFI_CDS1903	ENOG4108IXY	short-chain dehydrogenase reductase
VITFI_CDS1905	ENOG4105CXN	decarboxylase
VITFI_CDS1906	ENOG4105CHC	glucokinase (EC 2.7.1.2)
VITFI_CDS1907	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
VITFI_CDS1908	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
VITFI_CDS1909	ENOG4105CHV	Transcription elongation factor NusA
VITFI_CDS1910	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
VITFI_CDS1911	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
VITFI_CDS1912	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
VITFI_CDS1913	ENOG4105CI3	gtp-binding protein typa
VITFI_CDS1915	ENOG4108IPJ	Membrane
VITFI_CDS1916	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
VITFI_CDS1918	ENOG4108VWS	Yaeq family
VITFI_CDS1919	ENOG4105C1J	atp-dependent rna helicase
VITFI_CDS1924	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
VITFI_CDS1926	ENOG4105C5I	Dehydrogenase
VITFI_CDS1927	ENOG4105C5I	Dehydrogenase
VITFI_CDS1928	ENOG4105CSM	endonuclease III
VITFI_CDS1929	ENOG4108R3D	Electron transport complex
VITFI_CDS1932	ENOG4105CGF	Aromatic amino acid aminotransferase
VITFI_CDS1933	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
VITFI_CDS1934	ENOG4105KJF	protein tyrosine phosphatase
VITFI_CDS1935	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
VITFI_CDS1936	ENOG4105C3J	Cysteine desulfurase
VITFI_CDS1937	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
VITFI_CDS1938	ENOG4108Z4V	iron-sulfur cluster assembly
VITFI_CDS1940	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
VITFI_CDS1941	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
VITFI_CDS1942	ENOG4108ZIT	Ferredoxin, 2FE-2S
VITFI_CDS1943	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
VITFI_CDS1944	ENOG4105ES9	amino acid
VITFI_CDS1945	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
VITFI_CDS1947	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
VITFI_CDS1949	ENOG4105CP7	Triose-phosphate isomerase
VITFI_CDS1950	ENOG4107EJC	Preprotein translocase subunit SecG
VITFI_CDS1951	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
VITFI_CDS1952	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
VITFI_CDS1953	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
VITFI_CDS1954	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
VITFI_CDS1955	ENOG4105GKE	subunit e
VITFI_CDS1957	ENOG4108IEH	NADH dehydrogenase subunit g
VITFI_CDS1958	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
VITFI_CDS1959	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
VITFI_CDS1960	ENOG4105DF2	NADH dehydrogenase subunit j
VITFI_CDS1961	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
VITFI_CDS1963	ENOG4105C8S	subunit m
VITFI_CDS1964	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
VITFI_CDS1966	ENOG4108YZ4	nudix hydrolase
VITFI_CDS1968	ENOG4105CQB	FAD linked oxidase domain protein
VITFI_CDS1970	ENOG4107S2Z	UPF0761 membrane protein
VITFI_CDS1971	ENOG4108NVM	synthesis repressor PhaR
VITFI_CDS1972	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
VITFI_CDS1973	ENOG4105FFC	UPF0187 protein
VITFI_CDS1974	ENOG4105C28	cystathionine
VITFI_CDS1975	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
VITFI_CDS1977	ENOG4105VDB	UPF0125 protein
VITFI_CDS1979	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
VITFI_CDS1982	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
VITFI_CDS1987	ENOG4105VT2	5-hydroxyisourate hydrolase
VITFI_CDS1988	ENOG4108QBF	Transcriptional regulator
VITFI_CDS1991	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
VITFI_CDS1992	ENOG4107Z6I	Thiamine biosynthesis protein
VITFI_CDS1993	ENOG4105D7T	ABC transporter
VITFI_CDS1994	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
VITFI_CDS1996	ENOG4108Z6B	deaminase
VITFI_CDS1997	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
VITFI_CDS1999	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
VITFI_CDS2008	ENOG4105E18	UPF0276 protein
VITFI_CDS2010	ENOG4107QHF	type ii secretion system protein e
VITFI_CDS2012	ENOG4105M8F	Biopolymer transport protein exbD tolR
VITFI_CDS2013	ENOG4105E02	MotA TolQ exbB proton channel
VITFI_CDS2014	ENOG4107YD3	Thioesterase
VITFI_CDS2015	ENOG4105D9P	serine threonine protein kinase
VITFI_CDS2016	ENOG4105CHM	Aminotransferase
VITFI_CDS2017	ENOG4107YIM	Involved in the transcription termination process (By similarity)
VITFI_CDS2018	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
VITFI_CDS2019	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
VITFI_CDS2020	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
VITFI_CDS2022	ENOG4105DND	Transcriptional regulator
VITFI_CDS2023	ENOG4105KY5	gCN5-related N-acetyltransferase
VITFI_CDS2027	ENOG4105CPK	Glycosyl transferase (Group 1
VITFI_CDS2031	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
VITFI_CDS2032	ENOG4105CJ1	ABC, transporter
VITFI_CDS2041	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
VITFI_CDS2042	ENOG4108KX4	response regulator
VITFI_CDS2043	ENOG4105BZU	Histidine kinase
VITFI_CDS2046	ENOG4105E09	nadh pyrophosphatase
VITFI_CDS2049	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
VITFI_CDS2051	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
VITFI_CDS2052	ENOG4105CHU	acetyl-coa acetyltransferase
VITFI_CDS2053	ENOG4105CHR	reductase
VITFI_CDS2061	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
VITFI_CDS2062	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
VITFI_CDS2063	ENOG4105BZU	Histidine kinase
VITFI_CDS2064	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
VITFI_CDS2066	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
VITFI_CDS2069	ENOG4105DHQ	Histidine kinase
VITFI_CDS2077	ENOG4105DHQ	Histidine kinase
VITFI_CDS2079	ENOG4105VEJ	Heat shock protein
VITFI_CDS2080	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VITFI_CDS2081	ENOG4105CFG	Acts as a chaperone (By similarity)
VITFI_CDS2082	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
VITFI_CDS2083	ENOG4105CDU	Replicative dna helicase
VITFI_CDS2084	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
VITFI_CDS2085	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
VITFI_CDS2087	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
VITFI_CDS2088	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
VITFI_CDS2090	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
VITFI_CDS2096	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
VITFI_CDS2097	ENOG4108JA2	transcriptioN-repair coupling factor
VITFI_CDS2099	ENOG4108ECM	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) (By similarity)
VITFI_CDS2100	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
VITFI_CDS2101	ENOG4105E0F	Histidine kinase
VITFI_CDS2102	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
VITFI_CDS2103	ENOG4105DTD	Dehydrogenase
VITFI_CDS2105	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
VITFI_CDS2107	ENOG4105CY0	Metallo-Beta-Lactamase
VITFI_CDS2108	ENOG4105C1J	atp-dependent rna helicase
VITFI_CDS2109	ENOG4105C5H	ABC transporter
VITFI_CDS2112	ENOG4105EAB	amino acid AbC transporter
VITFI_CDS2128	ENOG41084EC	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
VITFI_CDS2148	ENOG4105CGH	5'-nucleotidase
VITFI_CDS2150	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
VITFI_CDS2152	ENOG4105DSY	exodeoxyribonuclease V, gamma
VITFI_CDS2153	ENOG4107QKA	exodeoxyribonuclease V beta
VITFI_CDS2154	ENOG4107QYX	exodeoxyribonuclease v alpha
VITFI_CDS2155	ENOG4106KED	esterase YpfH
VITFI_CDS2156	ENOG4105D1Q	UPF0246 protein
VITFI_CDS2160	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
VITFI_CDS2165	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
VITFI_CDS2167	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
VITFI_CDS2168	ENOG4108C33	Resolvase
VITFI_CDS2173	ENOG4105DQR	SNARE associated Golgi
VITFI_CDS2174	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
VITFI_CDS2175	ENOG4105FE9	pseudouridine synthase
VITFI_CDS2176	ENOG4105E5M	Multidrug resistance protein D
VITFI_CDS2177	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
VITFI_CDS2180	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
VITFI_CDS2184	ENOG4105CFV	Tetratricopeptide repeat protein
VITFI_CDS2186	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
VITFI_CDS2189	ENOG4105C8N	cysteinyl-tRNA synthetase
VITFI_CDS2191	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
VITFI_CDS2192	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
VITFI_CDS2193	ENOG4105CFH	Aspartokinase
VITFI_CDS2194	ENOG4105CVR	type I restriction-modification system
VITFI_CDS2197	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
VITFI_CDS2202	ENOG4105C26	Dehydrogenase
VITFI_CDS2204	ENOG4105D38	putrescine abc transporter
VITFI_CDS2205	ENOG4105F38	ABC transporter, permease
VITFI_CDS2206	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
VITFI_CDS2207	ENOG4107RUE	extracellular solute-binding protein family 1
VITFI_CDS2208	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
VITFI_CDS2210	ENOG4105CFQ	glutamine synthetase
VITFI_CDS2211	ENOG4108Z86	Glutamine amidotransferase
VITFI_CDS2212	ENOG4105F7P	transcriptional regulator AsnC family
VITFI_CDS2214	ENOG4105CYW	agmatinase
VITFI_CDS2215	ENOG4108I9X	Isocitrate lyase
VITFI_CDS2218	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
VITFI_CDS2223	ENOG4105CFP	Peptidase U32
VITFI_CDS2224	ENOG4105F8V	Hydrolase, tatD family
VITFI_CDS2226	ENOG4107QRG	dna polymerase iii
VITFI_CDS2227	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
VITFI_CDS2228	ENOG4105HHA	aminodeoxychorismate lyase
VITFI_CDS2229	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
VITFI_CDS2232	ENOG4105BZU	Histidine kinase
VITFI_CDS2235	ENOG4107QNJ	CoA-transferase subunit B
VITFI_CDS2237	ENOG4108ZXC	Two component transcriptional regulator, luxr family
VITFI_CDS2241	ENOG4105CFQ	glutamine synthetase
VITFI_CDS2242	ENOG4105DB7	PHP domain protein
VITFI_CDS2243	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
VITFI_CDS2245	ENOG4105M4H	endoribonuclease L-psp
VITFI_CDS2246	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
VITFI_CDS2247	ENOG4108Z66	YbaK ebsC protein
VITFI_CDS2248	ENOG4105CPC	Aldo Keto reductase
VITFI_CDS2249	ENOG4105E39	Enoyl-CoA hydratase
VITFI_CDS2250	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
VITFI_CDS2251	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
VITFI_CDS2252	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VITFI_CDS2255	ENOG4105EKQ	RNA-directed DNA polymerase
VITFI_CDS2256	ENOG4105EKQ	RNA-directed DNA polymerase
VITFI_CDS2257	ENOG4105EKQ	RNA-directed DNA polymerase
VITFI_CDS2258	ENOG4105EKQ	RNA-directed DNA polymerase
VITFI_CDS2263	ENOG4105WZK	nitrite reductase NADPH small subunit
VITFI_CDS2264	ENOG4107QZF	nitrite reductase NADPH large subunit
VITFI_CDS2265	ENOG4105EAC	phosphoserine phosphatase
VITFI_CDS2266	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
VITFI_CDS2268	ENOG4105BZU	Histidine kinase
VITFI_CDS2269	ENOG4105CQ7	ATP-dependent helicase
VITFI_CDS2271	ENOG4108EKC	n-acetylglutamate synthase
VITFI_CDS2272	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
VITFI_CDS2274	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
VITFI_CDS2276	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VITFI_CDS2277	ENOG4106R7G	Glycoside hydrolase family 5
VITFI_CDS2279	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
VITFI_CDS2283	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
VITFI_CDS2284	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
VITFI_CDS2285	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
VITFI_CDS2286	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
VITFI_CDS2287	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
VITFI_CDS2289	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VITFI_CDS2290	ENOG4105DZP	Membrane-associated zinc metalloprotease
VITFI_CDS2291	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
VITFI_CDS2292	ENOG4105KNE	Phosphatidate cytidylyltransferase
VITFI_CDS2294	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
VITFI_CDS2295	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
VITFI_CDS2296	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
VITFI_CDS2297	ENOG4105CE9	30S ribosomal protein S2
VITFI_CDS2298	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
VITFI_CDS2299	ENOG4108VPT	UPF0234 protein
VITFI_CDS2300	ENOG4105D4A	Cell wall formation (By similarity)
VITFI_CDS2301	ENOG4105BZU	Histidine kinase
VITFI_CDS2305	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
VITFI_CDS2306	ENOG4108UJV	acyl-CoA thioesterase i
VITFI_CDS2307	ENOG4108I0Y	(ABC) transporter
VITFI_CDS2308	ENOG4107TF3	peptidylprolyl cis-trans isomerase
VITFI_CDS2310	ENOG4107835	probably involved in intracellular septation (By similarity)
VITFI_CDS2311	ENOG4105E0X	reductase
VITFI_CDS2313	ENOG4105C32	Amino acid ABC transporter (Permease)
VITFI_CDS2315	ENOG4105C0Z	ABC transporter
VITFI_CDS2316	ENOG4108IV0	ABC, transporter
VITFI_CDS2321	ENOG4105E6M	Sulphatase-modifying factor protein
VITFI_CDS2322	ENOG4105E6M	Sulphatase-modifying factor protein
VITFI_CDS2327	ENOG4107YRI	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
VITFI_CDS2328	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
VITFI_CDS2331	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
VITFI_CDS2334	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
VITFI_CDS2335	ENOG4105K8N	protein family UPF0079, ATPase
VITFI_CDS2336	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
VITFI_CDS2339	ENOG4108Z9W	Outer membrane porin
VITFI_CDS2340	ENOG4105DRP	amino acid AbC transporter
VITFI_CDS2341	ENOG4106PMH	Extracellular solute-binding protein family 3
VITFI_CDS2342	ENOG4105ED9	Protein of unknown function (DUF455)
VITFI_CDS2343	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
VITFI_CDS2345	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
VITFI_CDS2348	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
VITFI_CDS2349	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
VITFI_CDS2350	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
VITFI_CDS2352	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
VITFI_CDS2353	ENOG4105ECY	inositol monophosphatase
VITFI_CDS2355	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
VITFI_CDS2356	ENOG4105D7W	serine acetyltransferase
VITFI_CDS2359	ENOG4108I0Y	(ABC) transporter
VITFI_CDS2360	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
VITFI_CDS2362	ENOG4105KHC	sulfurtransferase
VITFI_CDS2366	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
VITFI_CDS2369	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
VITFI_CDS2370	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
VITFI_CDS2376	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
VITFI_CDS2377	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
VITFI_CDS2379	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
VITFI_CDS2380	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
VITFI_CDS2381	ENOG4105E66	phosphoriboisomerase A
VITFI_CDS2382	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
VITFI_CDS2384	ENOG4105BZU	Histidine kinase
VITFI_CDS2385	ENOG4105DPX	Hydrogenase, large subunit
VITFI_CDS2386	ENOG4105E3S	small subunit
VITFI_CDS2387	ENOG4105BZU	Histidine kinase
VITFI_CDS2390	ENOG4105BZM	domain protein
VITFI_CDS2394	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
VITFI_CDS2395	ENOG4105F1N	DNA alkylation repair
VITFI_CDS2398	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
VITFI_CDS2399	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
VITFI_CDS2400	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
VITFI_CDS2403	ENOG4107SBE	Glycosyl transferase (Group 1
VITFI_CDS2404	ENOG4105D16	lipopolysaccharide heptosyltransferase i
VITFI_CDS2405	ENOG4107Z67	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
VITFI_CDS2407	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
VITFI_CDS2408	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
VITFI_CDS2409	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
VITFI_CDS2412	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
VITFI_CDS2414	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
VITFI_CDS2415	ENOG4105UYK	outer membrane protein a
VITFI_CDS2416	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
VITFI_CDS2417	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
VITFI_CDS2419	ENOG4105DZR	Type I site-specific deoxyribonuclease
VITFI_CDS2423	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
VITFI_CDS2424	ENOG4105BZJ	Electron transfer flavoprotein
VITFI_CDS2425	ENOG4105C10	Electron transfer flavoprotein
VITFI_CDS2426	ENOG4108WFY	phasin family
VITFI_CDS2428	ENOG4105DGU	Histone deacetylase
VITFI_CDS2432	ENOG4105DGW	oligopeptidase A
VITFI_CDS2433	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
VITFI_CDS2434	ENOG4108ZXC	Two component transcriptional regulator, luxr family
VITFI_CDS2435	ENOG4105BZU	Histidine kinase
VITFI_CDS2436	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
VITFI_CDS2437	ENOG4107QSN	dihydrolipoamide acetyltransferase
VITFI_CDS2438	ENOG4107QN2	dihydrolipoyl dehydrogenase
VITFI_CDS2442	ENOG4105KDC	50s ribosomal protein l28
VITFI_CDS2443	ENOG4105C3M	thioredoxin reductase
VITFI_CDS2444	ENOG4105CNU	cell division protein FtsK
VITFI_CDS2445	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
VITFI_CDS2446	ENOG4105D1H	recombination factor protein RarA
VITFI_CDS2447	ENOG4105C32	Amino acid ABC transporter (Permease)
VITFI_CDS2448	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
VITFI_CDS2449	ENOG4105C0Z	ABC transporter
VITFI_CDS2450	ENOG4108IV0	ABC, transporter
VITFI_CDS2451	ENOG4108R85	Short chain dehydrogenase
VITFI_CDS2452	ENOG4108YXG	UPF0502 protein
VITFI_CDS2454	ENOG4105E0K	tonB-dependent siderophore receptor
VITFI_CDS2455	ENOG4108Z4U	Ferredoxin
VITFI_CDS2456	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
VITFI_CDS2460	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
VITFI_CDS2461	ENOG4105D60	lipoprotein releasing system transmembrane protein
VITFI_CDS2472	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
VITFI_CDS2475	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
VITFI_CDS2477	ENOG4105C4K	Nad synthetase
VITFI_CDS2478	ENOG4108YZA	Nitrogen regulatory protein pii
VITFI_CDS2479	ENOG4108URH	decarboxylase
VITFI_CDS2480	ENOG41080IJ	Diacylglycerol kinase
VITFI_CDS2485	ENOG4105C7K	acetolactate synthase
VITFI_CDS2486	ENOG4108ZP8	Acetolactate synthase small subunit
VITFI_CDS2487	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
VITFI_CDS2488	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
VITFI_CDS2489	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
VITFI_CDS2491	ENOG41061WM	D-Alanyl-D-Alanine
VITFI_CDS2492	ENOG41069M3	Transcriptional regulator
VITFI_CDS2493	ENOG4107S11	squalene-associated FAD-dependent desaturase
VITFI_CDS2494	ENOG4105FE1	phytoene synthase
VITFI_CDS2496	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
VITFI_CDS2498	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
VITFI_CDS2499	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
VITFI_CDS2500	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
VITFI_CDS2501	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
VITFI_CDS2503	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
VITFI_CDS2504	ENOG4108IJ8	ABC transporter
VITFI_CDS2505	ENOG4108ETH	Formylglycinamide ribotide synthetase
VITFI_CDS2508	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
VITFI_CDS2509	ENOG4105DHQ	Histidine kinase
VITFI_CDS2516	ENOG4108RG3	short-chain dehydrogenase reductase
VITFI_CDS2517	ENOG41083B3	HAD-superfamily subfamily IB hydrolase
VITFI_CDS2518	ENOG4105BZ1	(ABC) transporter
VITFI_CDS2519	ENOG4105BZ1	(ABC) transporter
VITFI_CDS2520	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
VITFI_CDS2522	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
VITFI_CDS2526	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
VITFI_CDS2527	ENOG4105P8F	nudix hydrolase
VITFI_CDS2528	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
VITFI_CDS2529	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
VITFI_CDS2530	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
VITFI_CDS2531	ENOG4105K5M	30s ribosomal protein S16
VITFI_CDS2535	ENOG4107QXV	Phosphate transporter
VITFI_CDS2536	ENOG4107GRR	phosphate transport regulator
VITFI_CDS2537	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VITFI_CDS2538	ENOG4105DJ0	Poly(A) Polymerase
VITFI_CDS2541	ENOG4105C02	permease
VITFI_CDS2542	ENOG4105CJR	Integral membrane protein (MviN
VITFI_CDS2543	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
VITFI_CDS2545	ENOG4105C8Y	Acetylornithine aminotransferase
VITFI_CDS2546	ENOG4105DBV	ornithine carbamoyltransferase
VITFI_CDS2550	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
VITFI_CDS2551	ENOG4105C26	Dehydrogenase
VITFI_CDS2552	ENOG4105EW9	transcriptional regulator AsnC family
VITFI_CDS2553	ENOG4107RZZ	dna polymerase iii epsilon subunit
VITFI_CDS2554	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
VITFI_CDS2555	ENOG4105C01	Dihydroxy-acid dehydratase
VITFI_CDS2557	ENOG4105W2Z	cytochrome C, class I
VITFI_CDS2559	ENOG4108TEB	UPF0114 protein
VITFI_CDS2561	ENOG4105EGS	Mechanosensitive ion channel
VITFI_CDS2562	ENOG4105I8R	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VITFI_CDS2563	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
VITFI_CDS2570	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
VITFI_CDS2572	ENOG4105F8C	transglutaminase domain-containing protein
VITFI_CDS2573	ENOG4105CVE	Lytic murein transglycosylase
VITFI_CDS2576	ENOG4105HF0	Membrane
VITFI_CDS2577	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
VITFI_CDS2578	ENOG4105VCC	30S ribosomal protein S21
VITFI_CDS2582	ENOG4105RQF	LysR family Transcriptional regulator
VITFI_CDS2583	ENOG4105HEI	LysR family (Transcriptional regulator
VITFI_CDS2584	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
VITFI_CDS2585	ENOG4108KTG	Membrane protein, drug metabolite transporter
VITFI_CDS2587	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
VITFI_CDS2593	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
VITFI_CDS2594	ENOG4105CH5	extracellular solute-binding protein, family 7
VITFI_CDS2595	ENOG4105CH5	extracellular solute-binding protein, family 7
VITFI_CDS2596	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
VITFI_CDS2597	ENOG4105N42	UPF0307 protein
VITFI_CDS2598	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
VITFI_CDS2605	ENOG4105BZU	Histidine kinase
VITFI_CDS2606	ENOG4105BZU	Histidine kinase
VITFI_CDS2608	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
VITFI_CDS2609	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
VITFI_CDS2610	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
VITFI_CDS2611	ENOG4108IYU	L-aspartate oxidase
VITFI_CDS2612	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
VITFI_CDS2614	ENOG4107Z6W	Protein CrcB homolog
VITFI_CDS2615	ENOG4108ZAF	Molybdopterin
VITFI_CDS2616	ENOG4105M00	molybdopterin converting factor, subunit 1
VITFI_CDS2617	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
VITFI_CDS2618	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
VITFI_CDS2623	ENOG4105D6E	homoserine dehydrogenase
VITFI_CDS2624	ENOG4105CHM	Aminotransferase
VITFI_CDS2626	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VITFI_CDS2628	ENOG4108IAB	Phoh family
VITFI_CDS2629	ENOG4105K4H	Nlp p60 protein
VITFI_CDS2630	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
VITFI_CDS2631	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
VITFI_CDS2632	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
VITFI_CDS2633	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
VITFI_CDS2634	ENOG4105E9H	Lytic Murein transglycosylase
VITFI_CDS2635	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
VITFI_CDS2636	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
VITFI_CDS2637	ENOG4107QMP	dna polymerase iii subunits gamma and tau
VITFI_CDS2638	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
VITFI_CDS2640	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
VITFI_CDS2641	ENOG4107QN1	sodium solute
VITFI_CDS2645	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
VITFI_CDS2646	ENOG4105CD8	aminopeptidase N
VITFI_CDS2647	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
VITFI_CDS2650	ENOG410904N	short-chain dehydrogenase reductase
VITFI_CDS2652	ENOG4105D3G	Pseudouridine synthase
VITFI_CDS2655	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
VITFI_CDS2656	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
VITFI_CDS2658	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
VITFI_CDS2659	ENOG4105D5U	fad dependent oxidoreductase
VITFI_CDS2660	ENOG4105CSH	Transporter
VITFI_CDS2667	ENOG4105CWB	LysR family transcriptional Regulator
VITFI_CDS2668	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
VITFI_CDS2669	ENOG4105CEN	a g-specific adenine glycosylase
VITFI_CDS2670	ENOG410890F	Dynamin family
VITFI_CDS2671	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
VITFI_CDS2672	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
VITFI_CDS2673	ENOG4105VFU	Rna-binding protein
VITFI_CDS2676	ENOG41081V9	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
VITFI_CDS2677	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
VITFI_CDS2678	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
VITFI_CDS2679	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
VITFI_CDS2681	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
VITFI_CDS2682	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
VITFI_CDS2684	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
VITFI_CDS2685	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
VITFI_CDS2686	ENOG4106H78	methyltransferase
VITFI_CDS2687	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
VITFI_CDS2688	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
VITFI_CDS2689	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
VITFI_CDS2690	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
VITFI_CDS2691	ENOG4105CIH	Imidazole acetol-phosphate transaminase
VITFI_CDS2699	ENOG4105F4R	Transcriptional regulator mode
VITFI_CDS2702	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
VITFI_CDS2703	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
VITFI_CDS2704	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
VITFI_CDS2706	ENOG4105E3A	(ABC) transporter
VITFI_CDS2707	ENOG4105DA5	(ABC) transporter
VITFI_CDS2711	ENOG4105CBG	Sulfatase
VITFI_CDS2716	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
VITFI_CDS2717	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
VITFI_CDS2718	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
VITFI_CDS2719	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
VITFI_CDS2721	ENOG4105EPW	hflc protein
VITFI_CDS2722	ENOG4107QJR	hflk protein
VITFI_CDS2723	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
VITFI_CDS2724	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
VITFI_CDS2725	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
VITFI_CDS2728	ENOG4105CUT	histidyl-tRNA synthetase
VITFI_CDS2729	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
VITFI_CDS2732	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
VITFI_CDS2733	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
VITFI_CDS2734	ENOG4105FE9	pseudouridine synthase
VITFI_CDS2735	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
VITFI_CDS2736	ENOG4105C34	Pseudouridine synthase
VITFI_CDS2737	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VITFI_CDS2738	ENOG4105DVT	helicase
VITFI_CDS2740	ENOG4105D6Z	AFG1 family ATPase
VITFI_CDS2741	ENOG4107QN2	dihydrolipoyl dehydrogenase
VITFI_CDS2742	ENOG4105C7S	Dehydrogenase
VITFI_CDS2743	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
VITFI_CDS2747	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
VITFI_CDS2748	ENOG4108M8S	permease YjgP YjgQ family protein
VITFI_CDS2751	ENOG4107R11	Transcriptional regulator
VITFI_CDS2752	ENOG4105CHM	Aminotransferase
VITFI_CDS2754	ENOG4105F4R	Transcriptional regulator mode
VITFI_CDS2755	ENOG4105EWA	aspartate glutamate uridylate kinase
VITFI_CDS2756	ENOG4107YCI	aspartate glutamate uridylate kinase
VITFI_CDS2757	ENOG4107XWS	modD protein
VITFI_CDS2758	ENOG4108IJ6	ABC transporter
VITFI_CDS2759	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
VITFI_CDS2760	ENOG4105E0C	molybdate abc transporter
VITFI_CDS2761	ENOG4105PS4	nifq family
VITFI_CDS2762	ENOG4105WCA	Ferredoxin
VITFI_CDS2763	ENOG4105X87	nitrogen fixation
VITFI_CDS2764	ENOG4108VQE	nitrogen fixation protein
VITFI_CDS2765	ENOG4108UR2	Nitrogen fixation protein NifX
VITFI_CDS2766	ENOG4105DK8	Nitrogenase molybdenum-iron cofactor biosynthesis protein NifN
VITFI_CDS2773	ENOG4105BZU	Histidine kinase
VITFI_CDS2776	ENOG4105WN5	stage II sporulation protein
VITFI_CDS2779	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
VITFI_CDS2781	ENOG4105WH1	Two component transcriptional regulator luxr family
VITFI_CDS2782	ENOG4105BZU	Histidine kinase
VITFI_CDS2785	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
VITFI_CDS2787	ENOG4105WF7	pyrroloquinoline quinone biosynthesis protein d
VITFI_CDS2788	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
VITFI_CDS2789	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
VITFI_CDS2790	ENOG4105BZU	Histidine kinase
VITFI_CDS2791	ENOG41077A9	carbonic anhydrase
VITFI_CDS2793	ENOG4107RJX	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
VITFI_CDS2797	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
VITFI_CDS2798	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
VITFI_CDS2799	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
VITFI_CDS2800	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
VITFI_CDS2803	ENOG4105BZU	Histidine kinase
VITFI_CDS2804	ENOG4107YNJ	LysR family Transcriptional regulator
VITFI_CDS2805	ENOG4108JJ7	ABC transporter
VITFI_CDS2820	ENOG4105C1G	acyl-Coa dehydrogenase
VITFI_CDS2821	ENOG4107QX3	carboxylase
VITFI_CDS2825	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
VITFI_CDS2827	ENOG4108ZXC	Two component transcriptional regulator, luxr family
VITFI_CDS2838	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
VITFI_CDS2839	ENOG4105CVR	type I restriction-modification system
VITFI_CDS2841	ENOG4105DFS	Conserved Protein
VITFI_CDS2842	ENOG4107QTH	restriction modification system DNA specificity domain
VITFI_CDS2843	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
VITFI_CDS2844	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
VITFI_CDS2848	ENOG4105D9R	oxidoreductase
VITFI_CDS2851	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
VITFI_CDS2852	ENOG4105CHU	acetyl-coa acetyltransferase
VITFI_CDS2854	ENOG4105CSU	acyl-Coa dehydrogenase
VITFI_CDS2859	ENOG4105KHM	amidohydrolase 2
VITFI_CDS2860	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
VITFI_CDS2861	ENOG4105VTW	prevent-host-death family
VITFI_CDS2862	ENOG4105E9K	Isocitrate dehydrogenase
VITFI_CDS2865	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
VITFI_CDS2866	ENOG4105DC1	bifunctional purine biosynthesis protein purh
VITFI_CDS2867	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
VITFI_CDS2868	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
VITFI_CDS2869	ENOG4105W39	Membrane
VITFI_CDS2870	ENOG4105CTD	carboxy-peptidase
VITFI_CDS2871	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
VITFI_CDS2872	ENOG4105C7B	Threonine dehydratase
VITFI_CDS2873	ENOG4108UKZ	OsmC family
VITFI_CDS2874	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
VITFI_CDS2875	ENOG4108Z9W	Outer membrane porin
VITFI_CDS2876	ENOG4105DP0	ferredoxin-NADP reductase
VITFI_CDS2877	ENOG4105D0B	Nitrogenase protein alpha chain
VITFI_CDS2882	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
VITFI_CDS2883	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
VITFI_CDS2884	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
VITFI_CDS2887	ENOG4105EZE	Cupin 4 family protein
VITFI_CDS2889	ENOG4105GJM	(LipO)protein
VITFI_CDS2890	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
VITFI_CDS2896	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
VITFI_CDS2897	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
VITFI_CDS2898	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
VITFI_CDS2899	ENOG4105BZU	Histidine kinase
VITFI_CDS2900	ENOG4108STX	response regulator
VITFI_CDS2907	ENOG4105CDU	Replicative dna helicase
VITFI_CDS2912	ENOG4105DFP	Integrase
VITFI_CDS2913	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
VITFI_CDS2914	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
VITFI_CDS2916	ENOG4105YA8	Transcriptional regulator
VITFI_CDS2919	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
VITFI_CDS2921	ENOG4105DFG	type I secretion outer membrane protein
VITFI_CDS2922	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
VITFI_CDS2924	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
VITFI_CDS2926	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
VITFI_CDS2927	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
VITFI_CDS2929	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
VITFI_CDS2930	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
VITFI_CDS2931	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
VITFI_CDS2932	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
VITFI_CDS2933	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
VITFI_CDS2934	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
VITFI_CDS2936	ENOG4107QJH	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
VITFI_CDS2937	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
VITFI_CDS2938	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
VITFI_CDS2939	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
VITFI_CDS2942	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
VITFI_CDS2944	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
VITFI_CDS2945	ENOG4106A3M	Cytochrome p-450
VITFI_CDS2946	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
VITFI_CDS2947	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
VITFI_CDS2950	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
VITFI_CDS2951	ENOG4107QX3	carboxylase
VITFI_CDS2952	ENOG4105DJT	lAO AO transport system ATPase
VITFI_CDS2954	ENOG4105D5P	Methylmalonyl-coA mutase
VITFI_CDS2955	ENOG4105DRR	Transcriptional regulator, GntR family
VITFI_CDS2961	ENOG4105BZN	citrate synthase
VITFI_CDS2962	ENOG41060IS	Flavinator of succinate dehydrogenase
VITFI_CDS2963	ENOG4105E33	succinate dehydrogenase
VITFI_CDS2964	ENOG4108J01	L-aspartate oxidase
VITFI_CDS2967	ENOG4105FDP	GntR family transcriptional regulator
VITFI_CDS2968	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
VITFI_CDS2970	ENOG4107QIJ	Aconitate hydratase 2
VITFI_CDS2971	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
VITFI_CDS2973	ENOG41083X2	DNA polymerase III, epsilon subunit
VITFI_CDS2974	ENOG4108EX3	reductase
VITFI_CDS2978	ENOG4105C6T	cysteine synthase
VITFI_CDS2979	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
VITFI_CDS2980	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
VITFI_CDS2981	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
VITFI_CDS2983	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
VITFI_CDS2984	ENOG4108SER	Transposase
VITFI_CDS2989	ENOG410829K	Lysine exporter protein (Lyse ygga)
VITFI_CDS2990	ENOG4105ETT	transcriptional Regulator, LysR family
VITFI_CDS2991	ENOG4105C1G	acyl-Coa dehydrogenase
VITFI_CDS2992	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
VITFI_CDS2994	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
VITFI_CDS2995	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
VITFI_CDS2996	ENOG4105FR1	rard protein
VITFI_CDS2997	ENOG4105DY9	regulatoR
VITFI_CDS2998	ENOG4105CH7	arginosuccinase
VITFI_CDS3002	ENOG4105C9M	aspartyl-trna synthetase
VITFI_CDS3005	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
VITFI_CDS3007	ENOG4105CMR	udp-glucose 4-epimerase
VITFI_CDS3008	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
VITFI_CDS3011	ENOG4108MJ5	VirK protein
VITFI_CDS3019	ENOG4105KZX	Pterin carbinolamine dehydratase
VITFI_CDS3021	ENOG4108TIT	dATP pyrophosphohydrolase
VITFI_CDS3022	ENOG4105X23	Endonuclease Exonuclease phosphatase
VITFI_CDS3023	ENOG4105DZQ	phospholipase D Transphosphatidylase
VITFI_CDS3031	ENOG4105BZ1	(ABC) transporter
VITFI_CDS3032	ENOG4108DIG	cyanophycin synthetase
VITFI_CDS3033	ENOG4108DIG	cyanophycin synthetase
VITFI_CDS3044	ENOG4105C7K	acetolactate synthase
VITFI_CDS3046	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
VITFI_CDS3047	ENOG4105FAW	cDP-glucose 4,6-dehydratase
VITFI_CDS3048	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
VITFI_CDS3050	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
VITFI_CDS3051	ENOG4108JPW	Aminotransferase
VITFI_CDS3052	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
VITFI_CDS3054	ENOG4105F38	ABC transporter, permease
VITFI_CDS3059	ENOG4105CEY	Amp-dependent synthetase and ligase
VITFI_CDS3060	ENOG4105E39	Enoyl-CoA hydratase
VITFI_CDS3062	ENOG4108Z20	Acyl-transferase
VITFI_CDS3063	ENOG4105CD3	dihydroorotase
VITFI_CDS3064	ENOG4105CXT	aspartate transcarbamylase
VITFI_CDS3065	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
VITFI_CDS3066	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
VITFI_CDS3067	ENOG4108UJU	UPF0301 protein
VITFI_CDS3068	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
VITFI_CDS3069	ENOG4105CBS	Chea signal transduction histidine kinase
VITFI_CDS3070	ENOG4105C8Q	Methyl-accepting chemotaxis
VITFI_CDS3072	ENOG4105M3Z	response regulator
VITFI_CDS3073	ENOG4108UNF	response regulator
VITFI_CDS3074	ENOG4105VCQ	rubredoxin
VITFI_CDS3076	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
VITFI_CDS3078	ENOG4105DFU	Cell wall formation (By similarity)
VITFI_CDS3081	ENOG4105CHR	reductase
VITFI_CDS3084	ENOG4105E2X	shikimate dehydrogenase
VITFI_CDS3085	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
VITFI_CDS3087	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
VITFI_CDS3088	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
VITFI_CDS3089	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
VITFI_CDS3093	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
VITFI_CDS3094	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
VITFI_CDS3097	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VITFI_CDS3098	ENOG4107TUY	Histidine kinase
VITFI_CDS3099	ENOG4106KVJ	cytochrome C assembly protein
VITFI_CDS3100	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VITFI_CDS3102	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
VITFI_CDS3104	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
VITFI_CDS3105	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
VITFI_CDS3106	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
VITFI_CDS3108	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
VITFI_CDS3109	ENOG4105E4C	Lytic transglycosylase catalytic
VITFI_CDS3110	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
VITFI_CDS3111	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
VITFI_CDS3112	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
VITFI_CDS3113	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VITFI_CDS3114	ENOG4105K46	50S ribosomal protein l27
VITFI_CDS3115	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
VITFI_CDS3116	ENOG4105EAH	synthase
VITFI_CDS3117	ENOG4107QHF	type ii secretion system protein e
VITFI_CDS3120	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
VITFI_CDS3121	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
VITFI_CDS3124	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
VITFI_CDS3125	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
VITFI_CDS3126	ENOG41076E6	Uroporphyrinogen-III Synthase
VITFI_CDS3129	ENOG4105CHU	acetyl-coa acetyltransferase
VITFI_CDS3130	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
VITFI_CDS3132	ENOG4105E9F	Enoyl-CoA hydratase
VITFI_CDS3137	ENOG4105C0Z	ABC transporter
VITFI_CDS3138	ENOG4108IV0	ABC, transporter
VITFI_CDS3139	ENOG4105CSU	acyl-Coa dehydrogenase
VITFI_CDS3142	ENOG4105EKQ	RNA-directed DNA polymerase
VITFI_CDS3146	ENOG4105EDV	vault protein
VITFI_CDS3148	ENOG4105C7F	AcnD-accessory protein PrpF
VITFI_CDS3150	ENOG4106BRA	Membrane
VITFI_CDS3151	ENOG41062QD	Membrane
VITFI_CDS3152	ENOG4107QN1	sodium solute
VITFI_CDS3153	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
VITFI_CDS3154	ENOG4107S52	alpha-2-macroglobulin domain protein
VITFI_CDS3155	ENOG4105BZ4	penicillin-binding protein
VITFI_CDS3157	ENOG4105D7Q	type ii secretion system
VITFI_CDS3158	ENOG4107QHF	type ii secretion system protein e
VITFI_CDS3163	ENOG4108RTD	type II secretion system protein K
VITFI_CDS3164	ENOG4108WWZ	General secretion pathway protein J
VITFI_CDS3167	ENOG4108VAU	general secretion pathway protein G
VITFI_CDS3176	ENOG4105CNM	Receptor
VITFI_CDS3177	ENOG41090R7	Ferric uptake
VITFI_CDS3182	ENOG4107E2E	PKHD-type hydroxylase
VITFI_CDS3189	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
VITFI_CDS3195	ENOG4105C3G	gtp-binding protein
VITFI_CDS3205	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
VITFI_CDS3206	ENOG4105T95	Thiol disulfide interChange protein
VITFI_CDS3222	ENOG4105GAK	amidohydrolase 2
VITFI_CDS3226	ENOG4105CPC	Aldo Keto reductase
VITFI_CDS3233	ENOG4106A3M	Cytochrome p-450
VITFI_CDS3236	ENOG4105BZU	Histidine kinase
VITFI_CDS3239	ENOG4105FCD	Major Facilitator
VITFI_CDS3257	ENOG4105D9M	gamma-glutamylcysteine synthetase
VITFI_CDS3259	ENOG4107RP9	extracellular solute-binding protein, family 3
VITFI_CDS3261	ENOG4107RP9	extracellular solute-binding protein, family 3
VITFI_CDS3262	ENOG4105EAD	ABC transporter
VITFI_CDS3263	ENOG4105DRP	amino acid AbC transporter
VITFI_CDS3264	ENOG4105CDA	abc transporter atp-binding protein
VITFI_CDS3265	ENOG4105CQZ	Histidine kinase
VITFI_CDS3266	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VITFI_CDS3274	ENOG4105CQB	FAD linked oxidase domain protein
VITFI_CDS3280	ENOG4108W9H	Tetr family transcriptional regulator
VITFI_CDS3282	ENOG4105BZU	Histidine kinase
VITFI_CDS3286	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
VITFI_CDS3287	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
VITFI_CDS3288	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
VITFI_CDS3289	ENOG4107S9B	Shikimate dehydrogenase
VITFI_CDS3293	ENOG4105EA8	2-Nitropropane dioxygenase
VITFI_CDS3294	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
VITFI_CDS3297	ENOG4107THI	3,4-dihydroxyphenylacetate 2,3-dioxygenase
VITFI_CDS3298	ENOG4105C26	Dehydrogenase
VITFI_CDS3304	ENOG4108V8F	Transcriptional regulator, MarR family
VITFI_CDS3306	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
VITFI_CDS3310	ENOG4108YZT	Adenosylcobinamide kinase
VITFI_CDS3311	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
VITFI_CDS3315	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
VITFI_CDS3316	ENOG4105NZG	Ferredoxin
VITFI_CDS3317	ENOG4105E4R	Precorrin-3B C17-methyltransferase
VITFI_CDS3318	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
VITFI_CDS3319	ENOG4108P62	biosynthesis protein (CbiG)
VITFI_CDS3321	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
VITFI_CDS3322	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
VITFI_CDS3323	ENOG41081F0	Precorrin-8x methylmutase
VITFI_CDS3324	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
VITFI_CDS3325	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
VITFI_CDS3327	ENOG4105CIH	Imidazole acetol-phosphate transaminase
VITFI_CDS3328	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
VITFI_CDS3330	ENOG4108M0I	Transcriptional regulator
VITFI_CDS3332	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
VITFI_CDS3333	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
VITFI_CDS3334	ENOG4105E0A	ABC, transporter
VITFI_CDS3335	ENOG4105EHG	Permease protein
VITFI_CDS3337	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
VITFI_CDS3341	ENOG4105CA0	peroxidase
VITFI_CDS3342	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
VITFI_CDS3345	ENOG4105EVD	ribosomal RNA large subunit methyltransferase N
VITFI_CDS3348	ENOG4105C0H	protease
VITFI_CDS3352	ENOG4105C4W	S-formylglutathione hydrolase
VITFI_CDS3357	ENOG4105CVR	type I restriction-modification system
VITFI_CDS3358	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
VITFI_CDS3359	ENOG4108JUA	Transcriptional regulator
VITFI_CDS3363	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
VITFI_CDS3369	ENOG4105PNM	synthesis protein
VITFI_CDS3374	ENOG4105MSY	salicylate hydroxylase
VITFI_CDS3380	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
VITFI_CDS3381	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
VITFI_CDS3384	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
VITFI_CDS3387	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
VITFI_CDS3391	ENOG4105C28	cystathionine
VITFI_CDS3395	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
VITFI_CDS3396	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
VITFI_CDS3397	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
VITFI_CDS3399	ENOG410620I	Diguanylate cyclase
VITFI_CDS3400	ENOG4105EXC	Acyl-transferase
VITFI_CDS3402	ENOG4105CNV	Aldolase
VITFI_CDS3403	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
VITFI_CDS3404	ENOG4105MP9	class II Aldolase
VITFI_CDS3407	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
VITFI_CDS3408	ENOG4105EB3	Histidine kinase
VITFI_CDS3409	ENOG4105E3J	oxidoreductase
VITFI_CDS3411	ENOG4105EUP	HipA domain protein
VITFI_CDS3415	ENOG4105DXM	phenylacetic acid degradation protein
VITFI_CDS3417	ENOG4105CHU	acetyl-coa acetyltransferase
VITFI_CDS3418	ENOG4108IG5	Transcriptional regulator
VITFI_CDS3419	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
VITFI_CDS3420	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
VITFI_CDS3421	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
VITFI_CDS3422	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
VITFI_CDS3423	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
VITFI_CDS3425	ENOG4108ZJI	phenylacetic acid degradation protein
VITFI_CDS3426	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
VITFI_CDS3427	ENOG4108UKI	Enoyl-CoA hydratase
VITFI_CDS3430	ENOG4108UKI	Enoyl-CoA hydratase
VITFI_CDS3432	ENOG410811B	TRANSCRIPTIONal
VITFI_CDS3437	ENOG4105BZU	Histidine kinase
VITFI_CDS3440	ENOG4105BZU	Histidine kinase
VITFI_CDS3441	ENOG4105DHQ	Histidine kinase
VITFI_CDS3442	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
VITFI_CDS3445	ENOG4105BZU	Histidine kinase
VITFI_CDS3452	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
VITFI_CDS3453	ENOG4105BZS	acriflavin resistance protein
VITFI_CDS3454	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
VITFI_CDS3456	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
VITFI_CDS3457	ENOG4105EU8	FAD linked oxidase domain protein
VITFI_CDS3458	ENOG4105CQB	FAD linked oxidase domain protein
VITFI_CDS3461	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
VITFI_CDS3467	ENOG4107QX9	Thiol disulfide interChange protein
VITFI_CDS3468	ENOG4105DA4	cytochrome c-type biogenesis protein
VITFI_CDS3469	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
VITFI_CDS3471	ENOG41060IM	Heme exporter protein
VITFI_CDS3472	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
VITFI_CDS3473	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
VITFI_CDS3476	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
VITFI_CDS3477	ENOG4108BGM	Quinol dehydrogenase periplasmic component
VITFI_CDS3478	ENOG4105GXZ	Ferredoxin-type protein NapH
VITFI_CDS3480	ENOG4105CUW	cytochrome C-TYPE protein
VITFI_CDS3484	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
VITFI_CDS3490	ENOG4105DJ4	phosphatidylserine decarboxylase
VITFI_CDS3492	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
VITFI_CDS3495	ENOG4107S78	Band 7 protein
VITFI_CDS3496	ENOG4105PV3	Inner membrane protein yqiJ
VITFI_CDS3499	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
VITFI_CDS3501	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
VITFI_CDS3503	ENOG4105C0H	protease
VITFI_CDS3531	ENOG4105QHH	Antitoxin component of a toxin-antitoxin (TA) module. A labile antitoxin that counteracts the effect of the YafQ toxin. YafQ and DinJ together bind their own promoter, and by analogy to other TA modules probably repress its expression
VITFI_CDS3540	ENOG4108C33	Resolvase
VITFI_CDS3541	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
VITFI_CDS3544	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
VITFI_CDS3546	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
VITFI_CDS3547	ENOG4108C33	Resolvase