locus-tag	class	description
VITFI_CDS0004	COG2974	May be involved in recombination
VITFI_CDS0016	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VITFI_CDS0020	COG2719	SpoVR family
VITFI_CDS0021	COG2718	Belongs to the UPF0229 family
VITFI_CDS0022	COG2766	serine protein kinase
VITFI_CDS0024	COG1475	DNA binding
VITFI_CDS0026	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
VITFI_CDS0027	COG1192	Involved in chromosome partitioning
VITFI_CDS0029	COG0357	Ribosomal RNA small subunit methyltransferase G
VITFI_CDS0030	COG0445	tRNA wobble uridine modification
VITFI_CDS0039	COG2197	response regulator
VITFI_CDS0041	COG1668	transmembrane transport
VITFI_CDS0042	COG1131	(ABC) transporter
VITFI_CDS0043	COG0596	Alpha beta hydrolase
VITFI_CDS0045	COG0625	glutathione transferase activity
VITFI_CDS0051	COG4181	ATPase activity
VITFI_CDS0053	COG0803	Belongs to the bacterial solute-binding protein 9 family
VITFI_CDS0055	COG1121	(ABC) transporter
VITFI_CDS0057	COG0564	pseudouridine synthase activity
VITFI_CDS0060	COG2203	Gaf domain
VITFI_CDS0060	COG2199	diguanylate cyclase activity
VITFI_CDS0070	COG0187	DNA topoisomerase II activity
VITFI_CDS0072	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
VITFI_CDS0072	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
VITFI_CDS0073	COG0230	Belongs to the bacterial ribosomal protein bL34 family
VITFI_CDS0074	COG0594	ribonuclease P activity
VITFI_CDS0075	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
VITFI_CDS0076	COG0706	membrane insertase activity
VITFI_CDS0077	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
VITFI_CDS0079	COG0515	serine threonine protein kinase
VITFI_CDS0079	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VITFI_CDS0080	COG1569	PIN domain
VITFI_CDS0081	COG3311	Transcriptional regulator
VITFI_CDS0082	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VITFI_CDS0091	COG2076	Multidrug Resistance protein
VITFI_CDS0092	COG0745	RESPONSE REGULATOR receiver
VITFI_CDS0107	COG4397	Mu-like prophage major head subunit gpT
VITFI_CDS0113	COG4383	Mu-like prophage protein gp29
VITFI_CDS0114	COG4373	Mu-like prophage FluMu protein gp28
VITFI_CDS0128	COG2974	May be involved in recombination
VITFI_CDS0139	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VITFI_CDS0147	COG1129	ABC transporter
VITFI_CDS0148	COG0402	S-adenosylhomocysteine deaminase activity
VITFI_CDS0151	COG1529	Aldehyde oxidase and xanthine dehydrogenase
VITFI_CDS0153	COG0730	response to heat
VITFI_CDS0161	COG1172	Belongs to the binding-protein-dependent transport system permease family
VITFI_CDS0167	COG2205	protein histidine kinase activity
VITFI_CDS0167	COG2198	Histidine kinase
VITFI_CDS0167	COG0784	Response regulator, receiver
VITFI_CDS0168	COG2974	May be involved in recombination
VITFI_CDS0169	COG0653	protein targeting
VITFI_CDS0171	COG0739	heme binding
VITFI_CDS0173	COG2969	positive regulation of protein catabolic process
VITFI_CDS0174	COG0625	glutathione transferase activity
VITFI_CDS0175	COG2857	Cytochrome c1
VITFI_CDS0176	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VITFI_CDS0177	COG0723	plastoquinol--plastocyanin reductase activity
VITFI_CDS0178	COG1970	mechanosensitive ion channel activity
VITFI_CDS0179	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
VITFI_CDS0180	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VITFI_CDS0181	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VITFI_CDS0182	COG0805	protein transport
VITFI_CDS0183	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VITFI_CDS0184	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VITFI_CDS0185	COG0537	adenosine 5'-monophosphoramidase activity
VITFI_CDS0186	COG0140	phosphoribosyl-ATP diphosphatase activity
VITFI_CDS0187	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
VITFI_CDS0189	COG1309	transcriptional regulator
VITFI_CDS0191	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VITFI_CDS0197	COG3181	Tripartite tricarboxylate transporter family receptor
VITFI_CDS0203	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VITFI_CDS0206	COG1301	dicarboxylic acid transport
VITFI_CDS0210	COG1192	Involved in chromosome partitioning
VITFI_CDS0211	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
VITFI_CDS0212	COG2894	cell division
VITFI_CDS0213	COG0850	regulation of cytokinetic process
VITFI_CDS0214	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VITFI_CDS0215	COG2354	Protein conserved in bacteria
VITFI_CDS0216	COG1305	Transglutaminase-like
VITFI_CDS0217	COG2307	Protein conserved in bacteria
VITFI_CDS0217	COG2308	Evidence 4 Homologs of previously reported genes of
VITFI_CDS0220	COG2308	Evidence 4 Homologs of previously reported genes of
VITFI_CDS0230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VITFI_CDS0234	COG1253	flavin adenine dinucleotide binding
VITFI_CDS0235	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
VITFI_CDS0238	COG0717	Belongs to the dCTP deaminase family
VITFI_CDS0244	COG2824	Alkylphosphonate utilization operon protein PhnA
VITFI_CDS0247	COG0569	domain protein
VITFI_CDS0249	COG4651	solute:proton antiporter activity
VITFI_CDS0249	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VITFI_CDS0253	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
VITFI_CDS0254	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
VITFI_CDS0255	COG0291	Belongs to the bacterial ribosomal protein bL35 family
VITFI_CDS0256	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
VITFI_CDS0257	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
VITFI_CDS0258	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VITFI_CDS0258	COG0072	phenylalanine-tRNA ligase activity
VITFI_CDS0259	COG0776	regulation of translation
VITFI_CDS0263	COG2205	protein histidine kinase activity
VITFI_CDS0263	COG3850	Histidine kinase
VITFI_CDS0263	COG4999	Histidine kinase
VITFI_CDS0263	COG3437	response regulator, receiver
VITFI_CDS0264	COG0745	RESPONSE REGULATOR receiver
VITFI_CDS0268	COG4977	sequence-specific DNA binding
VITFI_CDS0270	COG0166	Belongs to the GPI family
VITFI_CDS0271	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
VITFI_CDS0272	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VITFI_CDS0273	COG1737	Transcriptional regulator
VITFI_CDS0273	COG0837	glucose binding
VITFI_CDS0276	COG2853	Lipoprotein
VITFI_CDS0277	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VITFI_CDS0278	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VITFI_CDS0279	COG1127	ABC transporter
VITFI_CDS0281	COG0070	glutamate synthase
VITFI_CDS0281	COG0069	glutamate synthase activity
VITFI_CDS0281	COG0067	glutamate synthase
VITFI_CDS0283	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
VITFI_CDS0284	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VITFI_CDS0292	COG1965	Belongs to the frataxin family
VITFI_CDS0294	COG1028	Short-chain dehydrogenase reductase Sdr
VITFI_CDS0300	COG3284	Transcriptional regulator
VITFI_CDS0301	COG1012	belongs to the aldehyde dehydrogenase family
VITFI_CDS0305	COG2925	Exonuclease
VITFI_CDS0308	COG3383	formate dehydrogenase (NAD+) activity
VITFI_CDS0313	COG3634	alkyl hydroperoxide reductase activity
VITFI_CDS0314	COG1672	PFAM Archaeal ATPase
VITFI_CDS0314	COG2319	Wd-40 repeat
VITFI_CDS0315	COG1672	PFAM Archaeal ATPase
VITFI_CDS0315	COG2319	Wd-40 repeat
VITFI_CDS0316	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VITFI_CDS0318	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
VITFI_CDS0322	COG0243	molybdopterin cofactor binding
VITFI_CDS0327	COG1473	amidohydrolase
VITFI_CDS0328	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VITFI_CDS0329	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VITFI_CDS0331	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
VITFI_CDS0333	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
VITFI_CDS0336	COG0588	phosphoglycerate mutase activity
VITFI_CDS0337	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VITFI_CDS0339	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
VITFI_CDS0340	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
VITFI_CDS0341	COG1040	competence protein
VITFI_CDS0342	COG2226	methyltransferase
VITFI_CDS0343	COG1999	signal sequence binding
VITFI_CDS0344	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VITFI_CDS0348	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VITFI_CDS0350	COG1024	Enoyl-CoA hydratase
VITFI_CDS0351	COG0583	DNA-binding transcription factor activity
VITFI_CDS0368	COG0446	pyridine nucleotide-disulphide oxidoreductase
VITFI_CDS0372	COG3058	Necessary for formate dehydrogenase activity
VITFI_CDS0373	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VITFI_CDS0374	COG2864	formate dehydrogenase
VITFI_CDS0375	COG0437	4 iron, 4 sulfur cluster binding
VITFI_CDS0376	COG3383	formate dehydrogenase (NAD+) activity
VITFI_CDS0376	COG0243	molybdopterin cofactor binding
VITFI_CDS0379	COG3852	Histidine kinase
VITFI_CDS0380	COG1072	(Pantothenic acid kinase))
VITFI_CDS0382	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VITFI_CDS0387	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VITFI_CDS0387	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VITFI_CDS0388	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VITFI_CDS0390	COG3300	MHYT domain
VITFI_CDS0390	COG5001	Diguanylate cyclase
VITFI_CDS0391	COG3706	GGDEF domain
VITFI_CDS0393	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VITFI_CDS0395	COG1203	CRISPR-associated helicase, Cas3
VITFI_CDS0401	COG1857	crispr-associated protein
VITFI_CDS0404	COG1518	maintenance of DNA repeat elements
VITFI_CDS0405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VITFI_CDS0416	COG0004	ammonium transporteR
VITFI_CDS0419	COG0800	Aldolase
VITFI_CDS0425	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
VITFI_CDS0426	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
VITFI_CDS0428	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
VITFI_CDS0429	COG0604	alcohol dehydrogenase
VITFI_CDS0431	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VITFI_CDS0436	COG1091	dTDP-4-dehydrorhamnose reductase activity
VITFI_CDS0438	COG0513	Belongs to the DEAD box helicase family
VITFI_CDS0439	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VITFI_CDS0440	COG0424	maF-like protein
VITFI_CDS0441	COG1399	metal-binding, possibly nucleic acid-binding protein
VITFI_CDS0442	COG0333	Belongs to the bacterial ribosomal protein bL32 family
VITFI_CDS0443	COG0416	fatty acid biosynthetic process
VITFI_CDS0444	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VITFI_CDS0445	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
VITFI_CDS0446	COG1028	Short-chain dehydrogenase reductase Sdr
VITFI_CDS0447	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VITFI_CDS0448	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VITFI_CDS0452	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VITFI_CDS0453	COG0481	GTPase activity
VITFI_CDS0456	COG0571	ribonuclease III activity
VITFI_CDS0457	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VITFI_CDS0458	COG1381	Involved in DNA repair and RecF pathway recombination
VITFI_CDS0459	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
VITFI_CDS0460	COG0736	holo-[acyl-carrier-protein] synthase activity
VITFI_CDS0463	COG1472	Belongs to the glycosyl hydrolase 3 family
VITFI_CDS0464	COG1530	ribonuclease E activity
VITFI_CDS0465	COG0564	pseudouridine synthase activity
VITFI_CDS0468	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VITFI_CDS0468	COG0616	signal peptide processing
VITFI_CDS0469	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
VITFI_CDS0470	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
VITFI_CDS0471	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VITFI_CDS0472	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
VITFI_CDS0473	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
VITFI_CDS0474	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
VITFI_CDS0476	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VITFI_CDS0477	COG1333	cytochrome c biogenesis protein
VITFI_CDS0479	COG0218	Necessary for normal cell division and for the maintenance of normal septation
VITFI_CDS0481	COG0459	protein refolding
VITFI_CDS0482	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VITFI_CDS0483	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
VITFI_CDS0490	COG0110	maltose O-acetyltransferase activity
VITFI_CDS0496	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VITFI_CDS0498	COG1538	Outer membrane efflux protein
VITFI_CDS0499	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VITFI_CDS0500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VITFI_CDS0503	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
VITFI_CDS0504	COG4585	Histidine kinase
VITFI_CDS0505	COG2197	response regulator
VITFI_CDS0506	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VITFI_CDS0508	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VITFI_CDS0509	COG1181	Belongs to the D-alanine--D-alanine ligase family
VITFI_CDS0510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VITFI_CDS0511	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
VITFI_CDS0512	COG0772	Belongs to the SEDS family
VITFI_CDS0513	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
VITFI_CDS0514	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
VITFI_CDS0515	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VITFI_CDS0516	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VITFI_CDS0519	COG0275	rRNA processing
VITFI_CDS0520	COG2814	Major facilitator Superfamily
VITFI_CDS0522	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VITFI_CDS0523	COG1758	RNA polymerase activity
VITFI_CDS0524	COG0194	GDP metabolic process
VITFI_CDS0525	COG1561	YicC-like family, N-terminal region
VITFI_CDS0527	COG0631	protein serine/threonine phosphatase activity
VITFI_CDS0528	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
VITFI_CDS0529	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
VITFI_CDS0531	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VITFI_CDS0534	COG1193	negative regulation of DNA recombination
VITFI_CDS0536	COG0307	riboflavin synthase, alpha
VITFI_CDS0537	COG2003	Belongs to the UPF0758 family
VITFI_CDS0538	COG2186	Transcriptional regulator
VITFI_CDS0539	COG0573	inorganic phosphate transmembrane transporter activity
VITFI_CDS0540	COG1176	ABC-type spermidine putrescine transport system, permease component I
VITFI_CDS0542	COG3842	ATPase activity
VITFI_CDS0544	COG1047	Peptidyl-prolyl cis-trans
VITFI_CDS0545	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VITFI_CDS0546	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
VITFI_CDS0547	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VITFI_CDS0548	COG0582	viral genome integration into host DNA
VITFI_CDS0563	COG2204	response regulator
VITFI_CDS0564	COG5000	phosphorelay sensor kinase activity
VITFI_CDS0571	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
VITFI_CDS0572	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
VITFI_CDS0574	COG0551	DNA topoisomerase type I activity
VITFI_CDS0574	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VITFI_CDS0582	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
VITFI_CDS0584	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
VITFI_CDS0587	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VITFI_CDS0593	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
VITFI_CDS0595	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VITFI_CDS0597	COG2267	carboxylic ester hydrolase activity
VITFI_CDS0598	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VITFI_CDS0600	COG4654	Cytochrome c, class I
VITFI_CDS0601	COG0191	fructose-bisphosphate aldolase activity
VITFI_CDS0602	COG0546	phosphoglycolate phosphatase activity
VITFI_CDS0603	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VITFI_CDS0604	COG3954	Phosphoribulokinase
VITFI_CDS0605	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
VITFI_CDS0606	COG0464	growth
VITFI_CDS0609	COG2369	cell adhesion
VITFI_CDS0611	COG4373	Mu-like prophage FluMu protein gp28
VITFI_CDS0640	COG2974	May be involved in recombination
VITFI_CDS0654	COG4373	Mu-like prophage FluMu protein gp28
VITFI_CDS0655	COG4383	Mu-like prophage protein gp29
VITFI_CDS0661	COG4397	Mu-like prophage major head subunit gpT
VITFI_CDS0676	COG3186	Phenylalanine-4-hydroxylase
VITFI_CDS0678	COG0583	DNA-binding transcription factor activity
VITFI_CDS0680	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
VITFI_CDS0686	COG1045	serine acetyltransferase
VITFI_CDS0688	COG0438	transferase activity, transferring glycosyl groups
VITFI_CDS0688	COG0297	glycogen (starch) synthase activity
VITFI_CDS0693	COG0489	protein tyrosine kinase activity
VITFI_CDS0699	COG1216	Glycosyl transferase, family 2
VITFI_CDS0699	COG0438	transferase activity, transferring glycosyl groups
VITFI_CDS0701	COG0792	nuclease activity
VITFI_CDS0702	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VITFI_CDS0703	COG2823	Periplasmic or secreted lipoprotein
VITFI_CDS0704	COG2084	Dehydrogenase
VITFI_CDS0708	COG2233	PERMEase
VITFI_CDS0712	COG0583	DNA-binding transcription factor activity
VITFI_CDS0714	COG0861	Integral membrane protein TerC family
VITFI_CDS0719	COG4239	(ABC) transporter, permease
VITFI_CDS0724	COG4166	transmembrane transport
VITFI_CDS0727	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
VITFI_CDS0729	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
VITFI_CDS0730	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
VITFI_CDS0733	COG0482	sulfurtransferase activity
VITFI_CDS0736	COG4783	chaperone-mediated protein folding
VITFI_CDS0737	COG0315	cyclic pyranopterin monophosphate synthase activity
VITFI_CDS0738	COG3307	-O-antigen
VITFI_CDS0743	COG1716	ATPase activity
VITFI_CDS0744	COG0631	protein serine/threonine phosphatase activity
VITFI_CDS0745	COG0861	Integral membrane protein TerC family
VITFI_CDS0746	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
VITFI_CDS0747	COG0045	succinate-CoA ligase (ADP-forming) activity
VITFI_CDS0749	COG2137	regulation of response to DNA damage stimulus
VITFI_CDS0750	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VITFI_CDS0752	COG0642	Histidine kinase
VITFI_CDS0753	COG0772	Belongs to the SEDS family
VITFI_CDS0754	COG0768	penicillin binding
VITFI_CDS0757	COG1077	Cell shape determining protein MreB Mrl
VITFI_CDS0758	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
VITFI_CDS0759	COG0154	amidase activity
VITFI_CDS0760	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
VITFI_CDS0761	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
VITFI_CDS0762	COG0708	Exodeoxyribonuclease III
VITFI_CDS0763	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VITFI_CDS0767	COG2223	nitrite transmembrane transporter activity
VITFI_CDS0773	COG2967	ApaG domain
VITFI_CDS0775	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VITFI_CDS0776	COG0546	phosphoglycolate phosphatase activity
VITFI_CDS0778	COG1196	nuclear chromosome segregation
VITFI_CDS0780	COG0512	Glutamine amidotransferase of anthranilate synthase
VITFI_CDS0782	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
VITFI_CDS0783	COG0134	indole-3-glycerol-phosphate synthase activity
VITFI_CDS0784	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
VITFI_CDS0786	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VITFI_CDS0789	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
VITFI_CDS0790	COG0081	regulation of translation
VITFI_CDS0792	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
VITFI_CDS0793	COG0222	ribosome binding
VITFI_CDS0795	COG0085	RNA polymerase activity
VITFI_CDS0796	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
VITFI_CDS0797	COG0352	thiamine-phosphate diphosphorylase activity
VITFI_CDS0797	COG0351	phosphomethylpyrimidine kinase
VITFI_CDS0798	COG2022	thiamine diphosphate biosynthetic process
VITFI_CDS0801	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
VITFI_CDS0806	COG2205	protein histidine kinase activity
VITFI_CDS0806	COG3850	Histidine kinase
VITFI_CDS0806	COG3437	response regulator, receiver
VITFI_CDS0806	COG4999	Histidine kinase
VITFI_CDS0807	COG2258	MOSC domain
VITFI_CDS0808	COG4636	protein conserved in cyanobacteria
VITFI_CDS0809	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
VITFI_CDS0811	COG1902	pentaerythritol trinitrate reductase activity
VITFI_CDS0814	COG1696	Membrane protein involved in D-alanine export
VITFI_CDS0815	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VITFI_CDS0819	COG5002	protein histidine kinase activity
VITFI_CDS0819	COG0784	Response regulator, receiver
VITFI_CDS0819	COG2205	protein histidine kinase activity
VITFI_CDS0825	COG2203	Gaf domain
VITFI_CDS0825	COG2199	diguanylate cyclase activity
VITFI_CDS0826	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VITFI_CDS0829	COG1560	Kdo2-lipid A biosynthetic process
VITFI_CDS0830	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
VITFI_CDS0832	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VITFI_CDS0835	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
VITFI_CDS0839	COG0446	pyridine nucleotide-disulphide oxidoreductase
VITFI_CDS0843	COG0640	Transcriptional regulator
VITFI_CDS0844	COG1937	Protein conserved in bacteria
VITFI_CDS0849	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
VITFI_CDS0850	COG1702	phosphate starvation-inducible protein PhoH
VITFI_CDS0851	COG0632	four-way junction helicase activity
VITFI_CDS0859	COG2255	four-way junction helicase activity
VITFI_CDS0861	COG0840	transmembrane signaling receptor activity
VITFI_CDS0862	COG0643	Histidine kinase
VITFI_CDS0862	COG2198	Histidine kinase
VITFI_CDS0867	COG1804	L-carnitine dehydratase bile acid-inducible protein F
VITFI_CDS0868	COG2032	superoxide dismutase activity
VITFI_CDS0873	COG0515	serine threonine protein kinase
VITFI_CDS0873	COG2815	serine threonine protein kinase
VITFI_CDS0886	COG0121	glutamine amidotransferase
VITFI_CDS0890	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VITFI_CDS0892	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VITFI_CDS0893	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VITFI_CDS0902	COG4654	Cytochrome c, class I
VITFI_CDS0903	COG0343	queuine tRNA-ribosyltransferase activity
VITFI_CDS0904	COG1116	anion transmembrane transporter activity
VITFI_CDS0904	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
VITFI_CDS0907	COG0625	glutathione transferase activity
VITFI_CDS0908	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VITFI_CDS0909	COG0284	orotidine-5'-phosphate decarboxylase activity
VITFI_CDS0910	COG1280	lysine exporter protein (LysE YggA)
VITFI_CDS0916	COG4628	conserved protein (DUF2132)
VITFI_CDS0919	COG1569	PIN domain
VITFI_CDS0922	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
VITFI_CDS0923	COG1522	sequence-specific DNA binding
VITFI_CDS0925	COG0543	2 iron, 2 sulfur cluster binding
VITFI_CDS0925	COG0633	Ferredoxin
VITFI_CDS0926	COG1151	hydroxylamine reductase activity
VITFI_CDS0929	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VITFI_CDS0930	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
VITFI_CDS0933	COG4452	Inner membrane protein CreD
VITFI_CDS0934	COG2205	protein histidine kinase activity
VITFI_CDS0935	COG2095	MarC family integral membrane protein
VITFI_CDS0936	COG0724	RNA recognition motif
VITFI_CDS0943	COG1028	Short-chain dehydrogenase reductase Sdr
VITFI_CDS0946	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VITFI_CDS0951	COG3344	reverse transcriptase
VITFI_CDS0955	COG2843	Capsule synthesis protein
VITFI_CDS0957	COG1760	l-serine dehydratase
VITFI_CDS0958	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VITFI_CDS0959	COG0612	Peptidase, M16
VITFI_CDS0962	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
VITFI_CDS0964	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VITFI_CDS0966	COG0018	arginyl-trna synthetase
VITFI_CDS0970	COG0583	DNA-binding transcription factor activity
VITFI_CDS0972	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
VITFI_CDS0973	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
VITFI_CDS0976	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VITFI_CDS0977	COG1819	glycosyl
VITFI_CDS0984	COG4654	Cytochrome c, class I
VITFI_CDS0985	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
VITFI_CDS0995	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
VITFI_CDS0996	COG0243	molybdopterin cofactor binding
VITFI_CDS0998	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VITFI_CDS0999	COG2815	serine threonine protein kinase
VITFI_CDS0999	COG0515	serine threonine protein kinase
VITFI_CDS1000	COG2223	nitrite transmembrane transporter activity
VITFI_CDS1002	COG0798	PFAM Bile acid sodium symporter
VITFI_CDS1003	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VITFI_CDS1004	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VITFI_CDS1015	COG1230	cation diffusion facilitator family transporter
VITFI_CDS1016	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
VITFI_CDS1019	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
VITFI_CDS1020	COG0321	lipoyl(octanoyl) transferase activity
VITFI_CDS1021	COG2921	Belongs to the UPF0250 family
VITFI_CDS1023	COG1686	Belongs to the peptidase S11 family
VITFI_CDS1025	COG3411	Ferredoxin
VITFI_CDS1029	COG0598	Magnesium transport protein CorA
VITFI_CDS1033	COG2226	methyltransferase
VITFI_CDS1034	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VITFI_CDS1037	COG0446	pyridine nucleotide-disulphide oxidoreductase
VITFI_CDS1040	COG1858	cytochrome C peroxidase
VITFI_CDS1041	COG0583	DNA-binding transcription factor activity
VITFI_CDS1042	COG1850	ribulose-bisphosphate carboxylase activity
VITFI_CDS1043	COG4451	ribulose bisphosphate carboxylase, small
VITFI_CDS1057	COG4397	Mu-like prophage major head subunit gpT
VITFI_CDS1064	COG4383	Mu-like prophage protein gp29
VITFI_CDS1065	COG4373	Mu-like prophage FluMu protein gp28
VITFI_CDS1079	COG2974	May be involved in recombination
VITFI_CDS1088	COG2205	protein histidine kinase activity
VITFI_CDS1092	COG1218	3'(2'),5'-bisphosphate nucleotidase
VITFI_CDS1093	COG0175	sulfate reduction
VITFI_CDS1095	COG0471	metal ion transport
VITFI_CDS1095	COG3273	potassium ion transport
VITFI_CDS1102	COG0356	it plays a direct role in the translocation of protons across the membrane
VITFI_CDS1104	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
VITFI_CDS1105	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
VITFI_CDS1106	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
VITFI_CDS1107	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VITFI_CDS1108	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
VITFI_CDS1109	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VITFI_CDS1113	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
VITFI_CDS1114	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VITFI_CDS1115	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VITFI_CDS1116	COG3162	membrane
VITFI_CDS1117	COG0210	DNA helicase
VITFI_CDS1119	COG3158	transport of potassium into the cell
VITFI_CDS1122	COG0004	ammonium transporteR
VITFI_CDS1125	COG3344	reverse transcriptase
VITFI_CDS1139	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VITFI_CDS1140	COG2096	Adenosyltransferase
VITFI_CDS1142	COG2201	protein-glutamate methylesterase activity
VITFI_CDS1143	COG2198	Histidine kinase
VITFI_CDS1143	COG0643	Histidine kinase
VITFI_CDS1145	COG1116	anion transmembrane transporter activity
VITFI_CDS1146	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
VITFI_CDS1147	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
VITFI_CDS1151	COG0318	PFAM AMP-dependent synthetase and ligase
VITFI_CDS1154	COG2030	dehydratase
VITFI_CDS1155	COG1960	acyl-CoA dehydrogenase activity
VITFI_CDS1156	COG0318	PFAM AMP-dependent synthetase and ligase
VITFI_CDS1157	COG0784	Response regulator, receiver
VITFI_CDS1157	COG4191	Histidine kinase
VITFI_CDS1158	COG0745	RESPONSE REGULATOR receiver
VITFI_CDS1160	COG2852	Protein conserved in bacteria
VITFI_CDS1161	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VITFI_CDS1163	COG0411	ABC transporter
VITFI_CDS1164	COG0559	Belongs to the binding-protein-dependent transport system permease family
VITFI_CDS1170	COG0183	Belongs to the thiolase family
VITFI_CDS1171	COG1960	acyl-CoA dehydrogenase activity
VITFI_CDS1172	COG1804	L-carnitine dehydratase bile acid-inducible protein F
VITFI_CDS1175	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
VITFI_CDS1175	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
VITFI_CDS1175	COG1703	isobutyryl-CoA mutase activity
VITFI_CDS1177	COG0583	DNA-binding transcription factor activity
VITFI_CDS1179	COG3706	GGDEF domain
VITFI_CDS1182	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
VITFI_CDS1187	COG0330	HflC and HflK could
VITFI_CDS1189	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
VITFI_CDS1194	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
VITFI_CDS1199	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VITFI_CDS1201	COG4566	intracellular signal transduction
VITFI_CDS1206	COG0180	Tryptophanyl-tRNA synthetase
VITFI_CDS1207	COG0697	spore germination
VITFI_CDS1209	COG1216	Glycosyl transferase, family 2
VITFI_CDS1214	COG0586	Pfam SNARE associated Golgi protein
VITFI_CDS1215	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VITFI_CDS1216	COG0277	FAD linked oxidase domain protein
VITFI_CDS1218	COG0312	modulator of DNA gyrase
VITFI_CDS1219	COG1448	Aminotransferase
VITFI_CDS1221	COG1858	cytochrome C peroxidase
VITFI_CDS1224	COG0745	RESPONSE REGULATOR receiver
VITFI_CDS1225	COG0642	Histidine kinase
VITFI_CDS1229	COG0438	transferase activity, transferring glycosyl groups
VITFI_CDS1230	COG0154	amidase activity
VITFI_CDS1232	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VITFI_CDS1234	COG0318	PFAM AMP-dependent synthetase and ligase
VITFI_CDS1235	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
VITFI_CDS1236	COG0049	tRNA binding
VITFI_CDS1237	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VITFI_CDS1238	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VITFI_CDS1239	COG0051	transcription antitermination factor activity, RNA binding
VITFI_CDS1240	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
VITFI_CDS1241	COG0088	Forms part of the polypeptide exit tunnel
VITFI_CDS1242	COG0089	rRNA binding
VITFI_CDS1243	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VITFI_CDS1244	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
VITFI_CDS1245	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
VITFI_CDS1246	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
VITFI_CDS1247	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
VITFI_CDS1248	COG0255	Belongs to the universal ribosomal protein uL29 family
VITFI_CDS1249	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
VITFI_CDS1250	COG0678	peroxiredoxin activity
VITFI_CDS1252	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
VITFI_CDS1253	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
VITFI_CDS1254	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VITFI_CDS1255	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
VITFI_CDS1256	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
VITFI_CDS1257	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
VITFI_CDS1258	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
VITFI_CDS1259	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
VITFI_CDS1260	COG1841	ribosomal large subunit assembly
VITFI_CDS1261	COG0200	Binds to the 23S rRNA
VITFI_CDS1262	COG0201	protein transport
VITFI_CDS1264	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VITFI_CDS1265	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VITFI_CDS1266	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
VITFI_CDS1267	COG0202	RNA polymerase activity
VITFI_CDS1268	COG0203	ribosomal protein L17
VITFI_CDS1269	COG4232	protein-disulfide reductase activity
VITFI_CDS1270	COG1862	Preprotein translocase
VITFI_CDS1271	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VITFI_CDS1272	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VITFI_CDS1274	COG2922	Belongs to the Smg family
VITFI_CDS1275	COG0758	DNA mediated transformation
VITFI_CDS1277	COG0242	peptide deformylase activity
VITFI_CDS1278	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
VITFI_CDS1279	COG0501	Belongs to the peptidase M48B family
VITFI_CDS1282	COG0126	phosphoglycerate kinase activity
VITFI_CDS1283	COG0281	malic enzyme
VITFI_CDS1283	COG0280	phosphate acetyltransferase
VITFI_CDS1284	COG0469	pyruvate kinase activity
VITFI_CDS1287	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
VITFI_CDS1290	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VITFI_CDS1291	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
VITFI_CDS1292	COG0009	L-threonylcarbamoyladenylate synthase
VITFI_CDS1296	COG2027	D-alanyl-D-alanine carboxypeptidase
VITFI_CDS1297	COG1214	PFAM Peptidase M22, glycoprotease
VITFI_CDS1298	COG0456	acetyltransferase
VITFI_CDS1310	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VITFI_CDS1311	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VITFI_CDS1322	COG0583	DNA-binding transcription factor activity
VITFI_CDS1323	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VITFI_CDS1325	COG0679	Auxin Efflux Carrier
VITFI_CDS1328	COG2176	DNA-directed DNA polymerase activity
VITFI_CDS1332	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
VITFI_CDS1335	COG2326	polyphosphate kinase activity
VITFI_CDS1338	COG4191	Histidine kinase
VITFI_CDS1339	COG4566	intracellular signal transduction
VITFI_CDS1342	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
VITFI_CDS1344	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VITFI_CDS1345	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
VITFI_CDS1346	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VITFI_CDS1348	COG3047	cAMP biosynthetic process
VITFI_CDS1350	COG0583	DNA-binding transcription factor activity
VITFI_CDS1359	COG0438	transferase activity, transferring glycosyl groups
VITFI_CDS1360	COG0726	polysaccharide deacetylase
VITFI_CDS1360	COG1649	PFAM Uncharacterised BCR, COG1649
VITFI_CDS1365	COG0037	tRNA processing
VITFI_CDS1366	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
VITFI_CDS1374	COG1028	Short-chain dehydrogenase reductase Sdr
VITFI_CDS1375	COG4569	acetaldehyde dehydrogenase (acetylating) activity
VITFI_CDS1376	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
VITFI_CDS1379	COG1802	Transcriptional regulator
VITFI_CDS1392	COG0247	lactate metabolic process
VITFI_CDS1393	COG0277	FAD linked oxidase domain protein
VITFI_CDS1394	COG0277	FAD linked oxidase domain protein
VITFI_CDS1401	COG0316	Belongs to the HesB IscA family
VITFI_CDS1404	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
VITFI_CDS1405	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
VITFI_CDS1409	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VITFI_CDS1410	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
VITFI_CDS1411	COG4208	sulfate ABC transporter
VITFI_CDS1412	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
VITFI_CDS1413	COG1715	Restriction endonuclease
VITFI_CDS1415	COG1196	nuclear chromosome segregation
VITFI_CDS1416	COG0513	Belongs to the DEAD box helicase family
VITFI_CDS1418	COG0583	DNA-binding transcription factor activity
VITFI_CDS1422	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
VITFI_CDS1423	COG0647	UMP catabolic process
VITFI_CDS1424	COG0598	Magnesium transport protein CorA
VITFI_CDS1425	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VITFI_CDS1427	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
VITFI_CDS1428	COG0735	belongs to the Fur family
VITFI_CDS1429	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VITFI_CDS1433	COG0495	leucyl-tRNA aminoacylation
VITFI_CDS1436	COG1546	Belongs to the CinA family
VITFI_CDS1436	COG1058	Belongs to the CinA family
VITFI_CDS1437	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VITFI_CDS1438	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
VITFI_CDS1439	COG0513	Belongs to the DEAD box helicase family
VITFI_CDS1443	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VITFI_CDS1451	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
VITFI_CDS1452	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VITFI_CDS1453	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
VITFI_CDS1455	COG0617	tRNA 3'-terminal CCA addition
VITFI_CDS1457	COG0739	heme binding
VITFI_CDS1457	COG0741	lytic transglycosylase activity
VITFI_CDS1457	COG1196	nuclear chromosome segregation
VITFI_CDS1459	COG0204	Acyl-transferase
VITFI_CDS1460	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VITFI_CDS1461	COG0751	glycine-tRNA ligase activity
VITFI_CDS1462	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VITFI_CDS1463	COG0752	glycyl-tRNA synthetase alpha subunit
VITFI_CDS1464	COG0815	Transfers the fatty acyl group on membrane lipoproteins
VITFI_CDS1466	COG0523	cobalamin synthesis protein
VITFI_CDS1467	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
VITFI_CDS1469	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
VITFI_CDS1470	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
VITFI_CDS1475	COG1490	D-aminoacyl-tRNA deacylase activity
VITFI_CDS1476	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
VITFI_CDS1477	COG0545	Peptidyl-prolyl cis-trans isomerase
VITFI_CDS1479	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VITFI_CDS1481	COG0784	Response regulator, receiver
VITFI_CDS1481	COG2205	protein histidine kinase activity
VITFI_CDS1485	COG0326	Molecular chaperone. Has ATPase activity
VITFI_CDS1489	COG0189	ligase activity
VITFI_CDS1490	COG3259	Nickel-dependent hydrogenase
VITFI_CDS1491	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
VITFI_CDS1492	COG3383	formate dehydrogenase (NAD+) activity
VITFI_CDS1493	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
VITFI_CDS1500	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VITFI_CDS1502	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
VITFI_CDS1505	COG1191	sigma factor activity
VITFI_CDS1506	COG0183	Belongs to the thiolase family
VITFI_CDS1516	COG2974	May be involved in recombination
VITFI_CDS1530	COG4373	Mu-like prophage FluMu protein gp28
VITFI_CDS1531	COG4383	Mu-like prophage protein gp29
VITFI_CDS1537	COG4397	Mu-like prophage major head subunit gpT
VITFI_CDS1557	COG3384	dioxygenase
VITFI_CDS1558	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
VITFI_CDS1561	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
VITFI_CDS1563	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
VITFI_CDS1565	COG0196	riboflavin kinase activity
VITFI_CDS1566	COG1187	pseudouridine synthase activity
VITFI_CDS1568	COG0204	Acyl-transferase
VITFI_CDS1568	COG0318	PFAM AMP-dependent synthetase and ligase
VITFI_CDS1575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VITFI_CDS1575	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
VITFI_CDS1579	COG1139	Iron-sulfur cluster binding protein
VITFI_CDS1582	COG2186	Transcriptional regulator
VITFI_CDS1583	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
VITFI_CDS1585	COG0668	transmembrane transport
VITFI_CDS1586	COG1024	Enoyl-CoA hydratase
VITFI_CDS1587	COG1250	3-hydroxyacyl-CoA dehydrogenase
VITFI_CDS1588	COG1024	Enoyl-CoA hydratase
VITFI_CDS1596	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VITFI_CDS1604	COG0411	ABC transporter
VITFI_CDS1606	COG0183	Belongs to the thiolase family
VITFI_CDS1612	COG1872	DUF167
VITFI_CDS1616	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VITFI_CDS1616	COG1042	CoA-binding domain protein
VITFI_CDS1616	COG0045	succinate-CoA ligase (ADP-forming) activity
VITFI_CDS1619	COG2205	protein histidine kinase activity
VITFI_CDS1620	COG0745	RESPONSE REGULATOR receiver
VITFI_CDS1622	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
VITFI_CDS1623	COG2832	Protein of unknown function (DUF454)
VITFI_CDS1625	COG1304	FMN binding
VITFI_CDS1627	COG0583	DNA-binding transcription factor activity
VITFI_CDS1629	COG1104	cysteine desulfurase activity
VITFI_CDS1630	COG0822	iron-sulfur transferase activity
VITFI_CDS1631	COG0316	Belongs to the HesB IscA family
VITFI_CDS1633	COG0443	Heat shock 70 kDa protein
VITFI_CDS1634	COG0633	Ferredoxin
VITFI_CDS1639	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
VITFI_CDS1643	COG3411	Ferredoxin
VITFI_CDS1645	COG2244	polysaccharide biosynthetic process
VITFI_CDS1648	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VITFI_CDS1652	COG5554	nitrogen fixation
VITFI_CDS1656	COG5554	nitrogen fixation
VITFI_CDS1658	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
VITFI_CDS1663	COG0617	tRNA 3'-terminal CCA addition
VITFI_CDS1676	COG0210	DNA helicase
VITFI_CDS1680	COG1722	exodeoxyribonuclease VII activity
VITFI_CDS1682	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
VITFI_CDS1683	COG1469	GTP cyclohydrolase I activity
VITFI_CDS1684	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
VITFI_CDS1691	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VITFI_CDS1692	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VITFI_CDS1694	COG0741	lytic transglycosylase activity
VITFI_CDS1695	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
VITFI_CDS1697	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VITFI_CDS1699	COG4771	TonB-dependent receptor
VITFI_CDS1700	COG0259	pyridoxamine-phosphate oxidase activity
VITFI_CDS1702	COG0746	molybdenum cofactor guanylyltransferase activity
VITFI_CDS1703	COG0489	protein tyrosine kinase activity
VITFI_CDS1707	COG0418	dihydroorotase activity
VITFI_CDS1710	COG3012	SEC-C Motif Domain Protein
VITFI_CDS1711	COG0564	pseudouridine synthase activity
VITFI_CDS1712	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
VITFI_CDS1714	COG3025	triphosphatase activity
VITFI_CDS1717	COG4232	protein-disulfide reductase activity
VITFI_CDS1729	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VITFI_CDS1730	COG0793	Belongs to the peptidase S41A family
VITFI_CDS1731	COG3842	ATPase activity
VITFI_CDS1734	COG0659	secondary active sulfate transmembrane transporter activity
VITFI_CDS1735	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VITFI_CDS1735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VITFI_CDS1736	COG0830	nickel cation binding
VITFI_CDS1737	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
VITFI_CDS1738	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
VITFI_CDS1739	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
VITFI_CDS1745	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
VITFI_CDS1746	COG1538	Outer membrane efflux protein
VITFI_CDS1748	COG1136	(ABC) transporter
VITFI_CDS1754	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
VITFI_CDS1756	COG0804	urea catabolic process
VITFI_CDS1757	COG0832	Belongs to the urease beta subunit family
VITFI_CDS1758	COG0831	urea catabolic process
VITFI_CDS1759	COG0366	Alpha amylase catalytic
VITFI_CDS1760	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
VITFI_CDS1762	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VITFI_CDS1763	COG0297	glycogen (starch) synthase activity
VITFI_CDS1764	COG0058	SHG alpha-glucan phosphorylase activity
VITFI_CDS1767	COG3275	phosphorelay sensor kinase activity
VITFI_CDS1773	COG1136	(ABC) transporter
VITFI_CDS1777	COG0433	COG0433 Predicted ATPase
VITFI_CDS1778	COG0217	transcriptional regulatory protein
VITFI_CDS1779	COG0151	Belongs to the GarS family
VITFI_CDS1780	COG0408	coproporphyrinogen oxidase activity
VITFI_CDS1781	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
VITFI_CDS1782	COG0799	negative regulation of ribosome biogenesis
VITFI_CDS1783	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
VITFI_CDS1788	COG0424	maF-like protein
VITFI_CDS1789	COG1530	ribonuclease E activity
VITFI_CDS1790	COG0823	Involved in the tonB-independent uptake of proteins
VITFI_CDS1793	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VITFI_CDS1794	COG1393	Belongs to the ArsC family
VITFI_CDS1795	COG0248	Ppx GppA phosphatase
VITFI_CDS1797	COG0745	RESPONSE REGULATOR receiver
VITFI_CDS1798	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
VITFI_CDS1799	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
VITFI_CDS1801	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VITFI_CDS1802	COG0670	Belongs to the BI1 family
VITFI_CDS1808	COG0505	Belongs to the CarA family
VITFI_CDS1810	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VITFI_CDS1811	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VITFI_CDS1814	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
VITFI_CDS1815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VITFI_CDS1817	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VITFI_CDS1818	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VITFI_CDS1819	COG0573	inorganic phosphate transmembrane transporter activity
VITFI_CDS1820	COG0581	inorganic phosphate transmembrane transporter activity
VITFI_CDS1821	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VITFI_CDS1823	COG0745	RESPONSE REGULATOR receiver
VITFI_CDS1826	COG0254	rRNA binding
VITFI_CDS1827	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
VITFI_CDS1831	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VITFI_CDS1832	COG0252	asparaginase activity
VITFI_CDS1834	COG2890	protein-(glutamine-N5) methyltransferase activity
VITFI_CDS1835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VITFI_CDS1837	COG2171	N-acyltransferase activity
VITFI_CDS1839	COG0436	Aminotransferase
VITFI_CDS1840	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
VITFI_CDS1841	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
VITFI_CDS1843	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
VITFI_CDS1845	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
VITFI_CDS1846	COG0298	carbon dioxide binding
VITFI_CDS1847	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VITFI_CDS1848	COG1773	rubredoxin
VITFI_CDS1849	COG1773	rubredoxin
VITFI_CDS1850	COG1773	rubredoxin
VITFI_CDS1851	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
VITFI_CDS1852	COG0375	protein maturation
VITFI_CDS1853	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
VITFI_CDS1854	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
VITFI_CDS1855	COG0298	carbon dioxide binding
VITFI_CDS1856	COG0409	Hydrogenase expression formation protein
VITFI_CDS1857	COG0309	Hydrogenase expression formation protein (HypE)
VITFI_CDS1860	COG3852	Histidine kinase
VITFI_CDS1870	COG0563	adenylate kinase activity
VITFI_CDS1871	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
VITFI_CDS1872	COG1663	tetraacyldisaccharide 4'-kinase activity
VITFI_CDS1872	COG2835	tetraacyldisaccharide 4'-kinase activity
VITFI_CDS1873	COG1663	tetraacyldisaccharide 4'-kinase activity
VITFI_CDS1874	COG0848	biopolymer transport protein
VITFI_CDS1875	COG0811	peptide transport
VITFI_CDS1876	COG1570	exodeoxyribonuclease VII activity
VITFI_CDS1877	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
VITFI_CDS1878	COG0745	RESPONSE REGULATOR receiver
VITFI_CDS1879	COG2205	protein histidine kinase activity
VITFI_CDS1883	COG0084	hydrolase, TatD family'
VITFI_CDS1884	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
VITFI_CDS1885	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VITFI_CDS1887	COG2217	Heavy metal translocating P-type atpase
VITFI_CDS1889	COG3278	Belongs to the heme-copper respiratory oxidase family
VITFI_CDS1895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VITFI_CDS1897	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VITFI_CDS1900	COG1278	Cold shock
VITFI_CDS1901	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
VITFI_CDS1902	COG0542	response to heat
VITFI_CDS1903	COG0300	oxidoreductase activity
VITFI_CDS1905	COG1982	Orn Lys Arg decarboxylase major
VITFI_CDS1906	COG0837	glucose binding
VITFI_CDS1907	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VITFI_CDS1908	COG0779	Required for maturation of 30S ribosomal subunits
VITFI_CDS1909	COG0195	Participates in both transcription termination and antitermination
VITFI_CDS1909	COG2251	uridine kinase activity
VITFI_CDS1910	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
VITFI_CDS1911	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
VITFI_CDS1912	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
VITFI_CDS1915	COG0697	spore germination
VITFI_CDS1918	COG4681	YaeQ
VITFI_CDS1919	COG0513	Belongs to the DEAD box helicase family
VITFI_CDS1924	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VITFI_CDS1927	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VITFI_CDS1928	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VITFI_CDS1929	COG2878	Part of a membrane complex involved in electron transport
VITFI_CDS1934	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VITFI_CDS1935	COG1959	2 iron, 2 sulfur cluster binding
VITFI_CDS1936	COG1104	cysteine desulfurase activity
VITFI_CDS1937	COG0822	iron-sulfur transferase activity
VITFI_CDS1938	COG0316	Belongs to the HesB IscA family
VITFI_CDS1940	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VITFI_CDS1941	COG0443	Heat shock 70 kDa protein
VITFI_CDS1942	COG0633	Ferredoxin
VITFI_CDS1943	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
VITFI_CDS1944	COG0683	leucine binding
VITFI_CDS1945	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VITFI_CDS1947	COG1185	polyribonucleotide nucleotidyltransferase activity
VITFI_CDS1949	COG0149	triose-phosphate isomerase activity
VITFI_CDS1951	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VITFI_CDS1952	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VITFI_CDS1953	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VITFI_CDS1954	COG0649	NAD binding
VITFI_CDS1955	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
VITFI_CDS1957	COG1034	ATP synthesis coupled electron transport
VITFI_CDS1958	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
VITFI_CDS1959	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VITFI_CDS1961	COG0713	ATP synthesis coupled electron transport
VITFI_CDS1964	COG1007	ATP synthesis coupled electron transport
VITFI_CDS1966	COG0494	nUDIX hydrolase
VITFI_CDS1968	COG0277	FAD linked oxidase domain protein
VITFI_CDS1970	COG1295	ribonuclease BN
VITFI_CDS1971	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
VITFI_CDS1972	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VITFI_CDS1973	COG3781	membrane
VITFI_CDS1974	COG0626	cystathionine gamma-synthase activity
VITFI_CDS1975	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
VITFI_CDS1977	COG2914	Belongs to the UPF0125 (RnfH) family
VITFI_CDS1982	COG0518	GMP synthase (glutamine-hydrolyzing) activity
VITFI_CDS1982	COG0519	Catalyzes the synthesis of GMP from XMP
VITFI_CDS1987	COG2351	hydroxyisourate hydrolase activity
VITFI_CDS1991	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VITFI_CDS1992	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
VITFI_CDS1993	COG1116	anion transmembrane transporter activity
VITFI_CDS1994	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
VITFI_CDS1996	COG0590	tRNA wobble adenosine to inosine editing
VITFI_CDS1997	COG1619	proteins homologs of microcin C7 resistance protein MccF
VITFI_CDS1999	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VITFI_CDS2008	COG3220	belongs to the UPF0276 family
VITFI_CDS2012	COG0848	biopolymer transport protein
VITFI_CDS2013	COG0811	peptide transport
VITFI_CDS2014	COG0824	Thioesterase
VITFI_CDS2015	COG2815	serine threonine protein kinase
VITFI_CDS2015	COG0515	serine threonine protein kinase
VITFI_CDS2017	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VITFI_CDS2018	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
VITFI_CDS2020	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VITFI_CDS2020	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VITFI_CDS2022	COG0583	DNA-binding transcription factor activity
VITFI_CDS2027	COG0438	transferase activity, transferring glycosyl groups
VITFI_CDS2032	COG1131	(ABC) transporter
VITFI_CDS2051	COG3243	poly(R)-hydroxyalkanoic acid synthase
VITFI_CDS2052	COG0183	Belongs to the thiolase family
VITFI_CDS2053	COG1028	Short-chain dehydrogenase reductase Sdr
VITFI_CDS2062	COG0024	Methionine aminopeptidase
VITFI_CDS2064	COG3437	response regulator, receiver
VITFI_CDS2066	COG0395	ABC-type sugar transport system, permease component
VITFI_CDS2069	COG0642	Histidine kinase
VITFI_CDS2079	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VITFI_CDS2080	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VITFI_CDS2081	COG0443	Heat shock 70 kDa protein
VITFI_CDS2082	COG0484	heat shock protein binding
VITFI_CDS2084	COG0359	binds to the 23S rRNA
VITFI_CDS2085	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
VITFI_CDS2087	COG0360	Binds together with S18 to 16S ribosomal RNA
VITFI_CDS2090	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
VITFI_CDS2096	COG3622	Belongs to the hyi family
VITFI_CDS2097	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
VITFI_CDS2099	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VITFI_CDS2099	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
VITFI_CDS2100	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
VITFI_CDS2101	COG2205	protein histidine kinase activity
VITFI_CDS2102	COG0745	RESPONSE REGULATOR receiver
VITFI_CDS2103	COG1028	Short-chain dehydrogenase reductase Sdr
VITFI_CDS2105	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VITFI_CDS2107	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
VITFI_CDS2108	COG0513	Belongs to the DEAD box helicase family
VITFI_CDS2109	COG0488	(ABC) transporter
VITFI_CDS2128	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
VITFI_CDS2148	COG0737	Belongs to the 5'-nucleotidase family
VITFI_CDS2150	COG1518	maintenance of DNA repeat elements
VITFI_CDS2152	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VITFI_CDS2153	COG1074	ATP-dependent DNA helicase activity
VITFI_CDS2154	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VITFI_CDS2155	COG0400	carboxylic ester hydrolase activity
VITFI_CDS2156	COG3022	response to hydroperoxide
VITFI_CDS2165	COG1136	(ABC) transporter
VITFI_CDS2167	COG1538	Outer membrane efflux protein
VITFI_CDS2168	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
VITFI_CDS2173	COG0586	Pfam SNARE associated Golgi protein
VITFI_CDS2174	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
VITFI_CDS2175	COG1187	pseudouridine synthase activity
VITFI_CDS2176	COG2814	Major facilitator Superfamily
VITFI_CDS2177	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
VITFI_CDS2180	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
VITFI_CDS2184	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VITFI_CDS2185	COG3228	Belongs to the MtfA family
VITFI_CDS2186	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VITFI_CDS2189	COG0215	cysteine-tRNA ligase activity
VITFI_CDS2191	COG0825	malonyl-CoA metabolic process
VITFI_CDS2192	COG0037	tRNA processing
VITFI_CDS2193	COG0527	aspartate kinase activity
VITFI_CDS2194	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VITFI_CDS2197	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VITFI_CDS2202	COG1012	belongs to the aldehyde dehydrogenase family
VITFI_CDS2204	COG1177	transmembrane transport
VITFI_CDS2205	COG1176	ABC-type spermidine putrescine transport system, permease component I
VITFI_CDS2206	COG3842	ATPase activity
VITFI_CDS2207	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VITFI_CDS2210	COG0174	glutamine synthetase
VITFI_CDS2211	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
VITFI_CDS2212	COG1522	sequence-specific DNA binding
VITFI_CDS2214	COG0010	Belongs to the arginase family
VITFI_CDS2215	COG2224	Isocitrate lyase
VITFI_CDS2218	COG0560	Phosphoserine phosphatase
VITFI_CDS2223	COG0826	peptidase U32
VITFI_CDS2224	COG0084	hydrolase, TatD family'
VITFI_CDS2227	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
VITFI_CDS2228	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VITFI_CDS2232	COG0004	ammonium transporteR
VITFI_CDS2235	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
VITFI_CDS2241	COG0174	glutamine synthetase
VITFI_CDS2242	COG0613	PHP domain protein
VITFI_CDS2243	COG0009	L-threonylcarbamoyladenylate synthase
VITFI_CDS2245	COG0251	oxidation-reduction process
VITFI_CDS2246	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
VITFI_CDS2248	COG0667	Aldo Keto reductase
VITFI_CDS2249	COG1024	Enoyl-CoA hydratase
VITFI_CDS2250	COG0404	The glycine cleavage system catalyzes the degradation of glycine
VITFI_CDS2251	COG0509	glycine decarboxylation via glycine cleavage system
VITFI_CDS2252	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VITFI_CDS2252	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VITFI_CDS2255	COG3344	reverse transcriptase
VITFI_CDS2256	COG3344	reverse transcriptase
VITFI_CDS2257	COG3344	reverse transcriptase
VITFI_CDS2258	COG3344	reverse transcriptase
VITFI_CDS2263	COG2146	nitrite reductase [NAD(P)H] activity
VITFI_CDS2264	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
VITFI_CDS2265	COG0560	Phosphoserine phosphatase
VITFI_CDS2266	COG0516	GMP reductase activity
VITFI_CDS2266	COG0517	IMP dehydrogenase activity
VITFI_CDS2269	COG1643	Atp-dependent helicase
VITFI_CDS2271	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VITFI_CDS2271	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VITFI_CDS2272	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
VITFI_CDS2273	COG1840	ABC-type Fe3 transport system, periplasmic component
VITFI_CDS2276	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VITFI_CDS2277	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
VITFI_CDS2279	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VITFI_CDS2282	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VITFI_CDS2283	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
VITFI_CDS2284	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VITFI_CDS2285	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VITFI_CDS2286	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VITFI_CDS2287	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VITFI_CDS2290	COG0750	zinc metalloprotease
VITFI_CDS2291	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
VITFI_CDS2292	COG0575	Belongs to the CDS family
VITFI_CDS2294	COG0233	cytoplasmic translational termination
VITFI_CDS2295	COG0528	UMP kinase activity
VITFI_CDS2296	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
VITFI_CDS2297	COG0052	Belongs to the universal ribosomal protein uS2 family
VITFI_CDS2298	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
VITFI_CDS2298	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
VITFI_CDS2299	COG1666	GTP binding
VITFI_CDS2300	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VITFI_CDS2305	COG0242	peptide deformylase activity
VITFI_CDS2307	COG4181	ATPase activity
VITFI_CDS2308	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VITFI_CDS2310	COG2917	probably involved in intracellular septation
VITFI_CDS2311	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VITFI_CDS2313	COG0559	Belongs to the binding-protein-dependent transport system permease family
VITFI_CDS2315	COG0411	ABC transporter
VITFI_CDS2316	COG0410	ABC transporter
VITFI_CDS2321	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VITFI_CDS2322	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VITFI_CDS2327	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VITFI_CDS2328	COG1196	nuclear chromosome segregation
VITFI_CDS2331	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
VITFI_CDS2334	COG0860	N-Acetylmuramoyl-L-alanine amidase
VITFI_CDS2335	COG0802	atpase or kinase
VITFI_CDS2336	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VITFI_CDS2339	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VITFI_CDS2340	COG0765	amino acid transport
VITFI_CDS2342	COG2833	Protein of unknown function (DUF455)
VITFI_CDS2343	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
VITFI_CDS2348	COG0148	phosphopyruvate hydratase activity
VITFI_CDS2349	COG2877	3-deoxy-8-phosphooctulonate synthase activity
VITFI_CDS2350	COG0504	CTP synthase activity
VITFI_CDS2352	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
VITFI_CDS2355	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
VITFI_CDS2356	COG1045	serine acetyltransferase
VITFI_CDS2359	COG4181	ATPase activity
VITFI_CDS2360	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VITFI_CDS2363	COG0589	response to stress
VITFI_CDS2366	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VITFI_CDS2369	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VITFI_CDS2370	COG0322	excinuclease ABC activity
VITFI_CDS2376	COG1518	maintenance of DNA repeat elements
VITFI_CDS2377	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
VITFI_CDS2379	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VITFI_CDS2380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
VITFI_CDS2380	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
VITFI_CDS2381	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
VITFI_CDS2382	COG0167	dihydroorotate dehydrogenase activity
VITFI_CDS2384	COG3852	Histidine kinase
VITFI_CDS2386	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
VITFI_CDS2387	COG3706	GGDEF domain
VITFI_CDS2388	COG2204	response regulator
VITFI_CDS2390	COG2183	response to ionizing radiation
VITFI_CDS2395	COG4335	DNA alkylation repair
VITFI_CDS2398	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VITFI_CDS2399	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
VITFI_CDS2400	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VITFI_CDS2403	COG0438	transferase activity, transferring glycosyl groups
VITFI_CDS2405	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
VITFI_CDS2407	COG0776	regulation of translation
VITFI_CDS2409	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
VITFI_CDS2410	COG0287	Prephenate dehydrogenase
VITFI_CDS2411	COG0077	Prephenate dehydratase
VITFI_CDS2411	COG1605	Chorismate mutase
VITFI_CDS2412	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VITFI_CDS2416	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VITFI_CDS2419	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
VITFI_CDS2423	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
VITFI_CDS2428	COG0123	including yeast histone deacetylase and acetoin utilization protein
VITFI_CDS2432	COG0339	signal peptide processing
VITFI_CDS2433	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
VITFI_CDS2434	COG4566	intracellular signal transduction
VITFI_CDS2435	COG4191	Histidine kinase
VITFI_CDS2437	COG0508	dehydrogenase complex catalyzes the overall conversion of
VITFI_CDS2438	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VITFI_CDS2439	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VITFI_CDS2439	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VITFI_CDS2442	COG0227	Belongs to the bacterial ribosomal protein bL28 family
VITFI_CDS2443	COG0492	ferredoxin-NADP+ reductase activity
VITFI_CDS2444	COG1674	ftsk spoiiie
VITFI_CDS2445	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
VITFI_CDS2446	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VITFI_CDS2451	COG1028	Short-chain dehydrogenase reductase Sdr
VITFI_CDS2452	COG3132	Protein of unknown function, DUF480
VITFI_CDS2454	COG4774	siderophore transport
VITFI_CDS2455	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
VITFI_CDS2456	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VITFI_CDS2456	COG1648	precorrin-2 dehydrogenase activity
VITFI_CDS2457	COG0175	sulfate reduction
VITFI_CDS2460	COG1136	(ABC) transporter
VITFI_CDS2461	COG4591	ABC-type transport system involved in lipoprotein release permease component
VITFI_CDS2472	COG0829	nickel cation binding
VITFI_CDS2475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VITFI_CDS2477	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
VITFI_CDS2477	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VITFI_CDS2480	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VITFI_CDS2485	COG0028	Belongs to the TPP enzyme family
VITFI_CDS2486	COG0440	acetolactate synthase activity
VITFI_CDS2487	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
VITFI_CDS2488	COG1183	phosphatidylcholine synthase activity
VITFI_CDS2489	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
VITFI_CDS2492	COG1414	Transcriptional regulator
VITFI_CDS2493	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
VITFI_CDS2495	COG1562	ergosterol biosynthetic process
VITFI_CDS2498	COG0544	peptidyl-prolyl cis-trans isomerase activity
VITFI_CDS2499	COG0740	serine-type endopeptidase activity
VITFI_CDS2500	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
VITFI_CDS2501	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VITFI_CDS2503	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
VITFI_CDS2504	COG1125	glycine betaine transport
VITFI_CDS2504	COG0517	IMP dehydrogenase activity
VITFI_CDS2505	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VITFI_CDS2505	COG0047	phosphoribosylformylglycinamidine synthase activity
VITFI_CDS2508	COG0745	RESPONSE REGULATOR receiver
VITFI_CDS2509	COG0642	Histidine kinase
VITFI_CDS2516	COG1028	Short-chain dehydrogenase reductase Sdr
VITFI_CDS2517	COG0560	Phosphoserine phosphatase
VITFI_CDS2518	COG1132	(ABC) transporter
VITFI_CDS2519	COG1132	(ABC) transporter
VITFI_CDS2520	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
VITFI_CDS2522	COG1162	GTPase activity
VITFI_CDS2526	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
VITFI_CDS2527	COG0494	nUDIX hydrolase
VITFI_CDS2528	COG0335	large ribosomal subunit rRNA binding
VITFI_CDS2529	COG0336	Belongs to the RNA methyltransferase TrmD family
VITFI_CDS2530	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
VITFI_CDS2531	COG0228	four-way junction DNA binding
VITFI_CDS2535	COG0306	phosphate transporter
VITFI_CDS2536	COG1392	Phosphate transport regulator
VITFI_CDS2538	COG0617	tRNA 3'-terminal CCA addition
VITFI_CDS2541	COG0628	permease
VITFI_CDS2542	COG0728	peptidoglycan biosynthetic process
VITFI_CDS2543	COG0268	Binds directly to 16S ribosomal RNA
VITFI_CDS2545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VITFI_CDS2546	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
VITFI_CDS2550	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
VITFI_CDS2553	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VITFI_CDS2554	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
VITFI_CDS2555	COG0129	dihydroxy-acid dehydratase activity
VITFI_CDS2557	COG4654	Cytochrome c, class I
VITFI_CDS2561	COG3264	Mechanosensitive ion channel
VITFI_CDS2561	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
VITFI_CDS2562	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VITFI_CDS2568	COG0123	including yeast histone deacetylase and acetoin utilization protein
VITFI_CDS2570	COG0714	Associated with various cellular activities
VITFI_CDS2573	COG2951	lytic endotransglycosylase activity
VITFI_CDS2576	COG0730	response to heat
VITFI_CDS2577	COG1250	3-hydroxyacyl-CoA dehydrogenase
VITFI_CDS2578	COG0828	Belongs to the bacterial ribosomal protein bS21 family
VITFI_CDS2582	COG0583	DNA-binding transcription factor activity
VITFI_CDS2583	COG0583	DNA-binding transcription factor activity
VITFI_CDS2584	COG1902	pentaerythritol trinitrate reductase activity
VITFI_CDS2585	COG0697	spore germination
VITFI_CDS2587	COG0019	diaminopimelate decarboxylase activity
VITFI_CDS2594	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VITFI_CDS2595	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VITFI_CDS2596	COG0312	modulator of DNA gyrase
VITFI_CDS2597	COG3028	Belongs to the UPF0307 family
VITFI_CDS2598	COG0521	Mo-molybdopterin cofactor biosynthetic process
VITFI_CDS2608	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VITFI_CDS2609	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
VITFI_CDS2611	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VITFI_CDS2612	COG0542	response to heat
VITFI_CDS2613	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
VITFI_CDS2614	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
VITFI_CDS2615	COG0314	molybdopterin synthase activity
VITFI_CDS2616	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VITFI_CDS2617	COG0303	'Molybdopterin
VITFI_CDS2618	COG1763	Mo-molybdopterin cofactor biosynthetic process
VITFI_CDS2624	COG0436	Aminotransferase
VITFI_CDS2626	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VITFI_CDS2628	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
VITFI_CDS2629	COG0791	NLP P60 protein
VITFI_CDS2630	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VITFI_CDS2631	COG0328	RNA-DNA hybrid ribonuclease activity
VITFI_CDS2633	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VITFI_CDS2634	COG1388	LysM domain
VITFI_CDS2634	COG0741	lytic transglycosylase activity
VITFI_CDS2635	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
VITFI_CDS2636	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
VITFI_CDS2637	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
VITFI_CDS2638	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
VITFI_CDS2640	COG2267	carboxylic ester hydrolase activity
VITFI_CDS2641	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VITFI_CDS2645	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
VITFI_CDS2646	COG0308	aminopeptidase N
VITFI_CDS2647	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
VITFI_CDS2650	COG1028	Short-chain dehydrogenase reductase Sdr
VITFI_CDS2652	COG0564	pseudouridine synthase activity
VITFI_CDS2655	COG1136	(ABC) transporter
VITFI_CDS2655	COG0577	efflux transmembrane transporter activity
VITFI_CDS2656	COG1136	(ABC) transporter
VITFI_CDS2656	COG0577	efflux transmembrane transporter activity
VITFI_CDS2659	COG0579	oxidoreductase
VITFI_CDS2664	COG1086	Polysaccharide biosynthesis protein
VITFI_CDS2666	COG1741	Belongs to the pirin family
VITFI_CDS2667	COG0583	DNA-binding transcription factor activity
VITFI_CDS2668	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VITFI_CDS2669	COG1194	a g-specific adenine glycosylase
VITFI_CDS2670	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
VITFI_CDS2671	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
VITFI_CDS2672	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VITFI_CDS2673	COG0724	RNA recognition motif
VITFI_CDS2676	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
VITFI_CDS2677	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
VITFI_CDS2678	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VITFI_CDS2679	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
VITFI_CDS2682	COG0193	aminoacyl-tRNA hydrolase activity
VITFI_CDS2684	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VITFI_CDS2685	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
VITFI_CDS2686	COG0742	ribosomal rna small subunit methyltransferase
VITFI_CDS2687	COG0107	imidazoleglycerol-phosphate synthase activity
VITFI_CDS2688	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
VITFI_CDS2689	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VITFI_CDS2690	COG0131	Imidazoleglycerol-phosphate dehydratase
VITFI_CDS2691	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VITFI_CDS2703	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
VITFI_CDS2704	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
VITFI_CDS2706	COG0842	Transport permease protein
VITFI_CDS2707	COG1131	(ABC) transporter
VITFI_CDS2711	COG3119	arylsulfatase activity
VITFI_CDS2716	COG0557	exoribonuclease II activity
VITFI_CDS2717	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
VITFI_CDS2718	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VITFI_CDS2719	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
VITFI_CDS2721	COG0330	HflC and HflK could
VITFI_CDS2722	COG0330	HflC and HflK could
VITFI_CDS2723	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VITFI_CDS2724	COG1923	regulation of RNA biosynthetic process
VITFI_CDS2725	COG1160	GTP binding
VITFI_CDS2728	COG0124	histidyl-tRNA synthetase
VITFI_CDS2729	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
VITFI_CDS2732	COG0820	rRNA (adenine-C2-)-methyltransferase activity
VITFI_CDS2733	COG0105	UTP biosynthetic process
VITFI_CDS2734	COG1187	pseudouridine synthase activity
VITFI_CDS2735	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
VITFI_CDS2736	COG0564	pseudouridine synthase activity
VITFI_CDS2738	COG1199	ATP-dependent helicase activity
VITFI_CDS2740	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VITFI_CDS2741	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VITFI_CDS2742	COG0508	dehydrogenase complex catalyzes the overall conversion of
VITFI_CDS2743	COG0567	Dehydrogenase, E1 component
VITFI_CDS2747	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VITFI_CDS2748	COG0795	lipopolysaccharide-transporting ATPase activity
VITFI_CDS2751	COG0583	DNA-binding transcription factor activity
VITFI_CDS2752	COG0436	Aminotransferase
VITFI_CDS2755	COG0528	UMP kinase activity
VITFI_CDS2756	COG0528	UMP kinase activity
VITFI_CDS2758	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
VITFI_CDS2759	COG0725	ABC transporter, periplasmic molybdate-binding protein
VITFI_CDS2760	COG4149	molybdate abc transporter
VITFI_CDS2762	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
VITFI_CDS2763	COG5420	small protein containing a coiled-coil domain
VITFI_CDS2766	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
VITFI_CDS2768	COG0612	Peptidase, M16
VITFI_CDS2773	COG5002	protein histidine kinase activity
VITFI_CDS2776	COG1366	Belongs to the anti-sigma-factor antagonist family
VITFI_CDS2779	COG0745	RESPONSE REGULATOR receiver
VITFI_CDS2781	COG2197	response regulator
VITFI_CDS2785	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
VITFI_CDS2788	COG0535	radical SAM domain protein
VITFI_CDS2789	COG1028	Short-chain dehydrogenase reductase Sdr
VITFI_CDS2790	COG3706	GGDEF domain
VITFI_CDS2791	COG0288	reversible hydration of carbon dioxide
VITFI_CDS2793	COG0602	queuosine metabolic process
VITFI_CDS2797	COG1420	regulation of RNA biosynthetic process
VITFI_CDS2798	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
VITFI_CDS2799	COG0497	DNA recombination
VITFI_CDS2800	COG1660	Displays ATPase and GTPase activities
VITFI_CDS2802	COG5001	Diguanylate cyclase
VITFI_CDS2802	COG4251	negative regulation of phosphorylation
VITFI_CDS2802	COG3706	GGDEF domain
VITFI_CDS2802	COG2203	Gaf domain
VITFI_CDS2803	COG2205	protein histidine kinase activity
VITFI_CDS2803	COG0784	Response regulator, receiver
VITFI_CDS2803	COG5002	protein histidine kinase activity
VITFI_CDS2804	COG0583	DNA-binding transcription factor activity
VITFI_CDS2805	COG5265	(ABC) transporter
VITFI_CDS2819	COG4636	protein conserved in cyanobacteria
VITFI_CDS2820	COG1960	acyl-CoA dehydrogenase activity
VITFI_CDS2821	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
VITFI_CDS2827	COG4566	intracellular signal transduction
VITFI_CDS2838	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VITFI_CDS2839	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VITFI_CDS2841	COG4804	nuclease activity
VITFI_CDS2842	COG0732	type I restriction modification DNA specificity domain
VITFI_CDS2843	COG2852	Protein conserved in bacteria
VITFI_CDS2844	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
VITFI_CDS2848	COG0673	inositol 2-dehydrogenase activity
VITFI_CDS2851	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VITFI_CDS2852	COG0183	Belongs to the thiolase family
VITFI_CDS2853	COG1250	3-hydroxyacyl-CoA dehydrogenase
VITFI_CDS2853	COG1024	Enoyl-CoA hydratase
VITFI_CDS2854	COG1960	acyl-CoA dehydrogenase activity
VITFI_CDS2859	COG2159	amidohydrolase
VITFI_CDS2860	COG4115	mRNA cleavage
VITFI_CDS2861	COG2161	toxin-antitoxin pair type II binding
VITFI_CDS2865	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
VITFI_CDS2866	COG0138	bifunctional purine biosynthesis protein purh
VITFI_CDS2867	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VITFI_CDS2868	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VITFI_CDS2869	COG1238	metal cluster binding
VITFI_CDS2870	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VITFI_CDS2871	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
VITFI_CDS2872	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
VITFI_CDS2873	COG1765	OsmC-like protein
VITFI_CDS2874	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
VITFI_CDS2877	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
VITFI_CDS2882	COG0653	protein targeting
VITFI_CDS2884	COG0756	dUTP diphosphatase activity
VITFI_CDS2885	COG4636	protein conserved in cyanobacteria
VITFI_CDS2887	COG2850	peptidyl-arginine hydroxylation
VITFI_CDS2889	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
VITFI_CDS2890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VITFI_CDS2896	COG0187	DNA topoisomerase II activity
VITFI_CDS2900	COG0745	RESPONSE REGULATOR receiver
VITFI_CDS2907	COG0305	Participates in initiation and elongation during chromosome replication
VITFI_CDS2912	COG0582	viral genome integration into host DNA
VITFI_CDS2913	COG0220	tRNA (guanine-N7-)-methyltransferase activity
VITFI_CDS2914	COG1968	undecaprenyl-diphosphatase activity
VITFI_CDS2916	COG1309	transcriptional regulator
VITFI_CDS2919	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
VITFI_CDS2921	COG1538	Outer membrane efflux protein
VITFI_CDS2924	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
VITFI_CDS2926	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VITFI_CDS2927	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VITFI_CDS2929	COG0285	dihydrofolate synthase activity
VITFI_CDS2930	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VITFI_CDS2931	COG0159	tryptophan synthase activity
VITFI_CDS2932	COG0133	tryptophan synthase activity
VITFI_CDS2933	COG0135	phosphoribosylanthranilate isomerase activity
VITFI_CDS2934	COG0101	tRNA pseudouridine synthase activity
VITFI_CDS2936	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VITFI_CDS2937	COG0473	3-isopropylmalate dehydrogenase activity
VITFI_CDS2938	COG0066	3-isopropylmalate dehydratase activity
VITFI_CDS2939	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
VITFI_CDS2944	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
VITFI_CDS2945	COG2124	cytochrome p450
VITFI_CDS2946	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
VITFI_CDS2947	COG0156	8-amino-7-oxononanoate synthase activity
VITFI_CDS2950	COG0439	Biotin carboxylase
VITFI_CDS2951	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
VITFI_CDS2952	COG1703	isobutyryl-CoA mutase activity
VITFI_CDS2954	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
VITFI_CDS2954	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
VITFI_CDS2955	COG1802	Transcriptional regulator
VITFI_CDS2961	COG0372	Belongs to the citrate synthase family
VITFI_CDS2962	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
VITFI_CDS2963	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VITFI_CDS2964	COG1053	succinate dehydrogenase
VITFI_CDS2967	COG2188	Transcriptional regulator
VITFI_CDS2968	COG0039	L-malate dehydrogenase activity
VITFI_CDS2970	COG1049	propionate catabolic process, 2-methylcitrate cycle
VITFI_CDS2971	COG2852	Protein conserved in bacteria
VITFI_CDS2973	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VITFI_CDS2974	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VITFI_CDS2974	COG0543	2 iron, 2 sulfur cluster binding
VITFI_CDS2979	COG0425	Belongs to the sulfur carrier protein TusA family
VITFI_CDS2980	COG1210	Utp--glucose-1-phosphate uridylyltransferase
VITFI_CDS2983	COG0714	Associated with various cellular activities
VITFI_CDS2984	COG3385	transposase activity
VITFI_CDS2989	COG1280	lysine exporter protein (LysE YggA)
VITFI_CDS2990	COG0583	DNA-binding transcription factor activity
VITFI_CDS2991	COG1960	acyl-CoA dehydrogenase activity
VITFI_CDS2992	COG1804	L-carnitine dehydratase bile acid-inducible protein F
VITFI_CDS2994	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
VITFI_CDS2995	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
VITFI_CDS2997	COG3279	Response regulator of the LytR AlgR family
VITFI_CDS2998	COG0165	Argininosuccinate lyase
VITFI_CDS3002	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
VITFI_CDS3005	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
VITFI_CDS3007	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VITFI_CDS3008	COG2226	methyltransferase
VITFI_CDS3011	COG2990	Protein conserved in bacteria
VITFI_CDS3019	COG2154	pterin-4-alpha-carbinolamine dehydratase
VITFI_CDS3021	COG0494	nUDIX hydrolase
VITFI_CDS3022	COG3568	Endonuclease Exonuclease Phosphatase
VITFI_CDS3023	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VITFI_CDS3031	COG1132	(ABC) transporter
VITFI_CDS3032	COG0189	ligase activity
VITFI_CDS3032	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VITFI_CDS3033	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VITFI_CDS3033	COG0189	ligase activity
VITFI_CDS3037	COG1215	transferase activity, transferring glycosyl groups
VITFI_CDS3038	COG0463	Glycosyl transferase, family 2
VITFI_CDS3044	COG0028	Belongs to the TPP enzyme family
VITFI_CDS3048	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
VITFI_CDS3050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VITFI_CDS3052	COG3842	ATPase activity
VITFI_CDS3054	COG1176	ABC-type spermidine putrescine transport system, permease component I
VITFI_CDS3059	COG0318	PFAM AMP-dependent synthetase and ligase
VITFI_CDS3060	COG1024	Enoyl-CoA hydratase
VITFI_CDS3064	COG0540	Belongs to the ATCase OTCase family
VITFI_CDS3065	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
VITFI_CDS3066	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VITFI_CDS3067	COG1678	Uncharacterized ACR, COG1678
VITFI_CDS3068	COG0415	Belongs to the DNA photolyase family
VITFI_CDS3069	COG0643	Histidine kinase
VITFI_CDS3069	COG2198	Histidine kinase
VITFI_CDS3070	COG0840	transmembrane signaling receptor activity
VITFI_CDS3074	COG1773	rubredoxin
VITFI_CDS3076	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
VITFI_CDS3078	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VITFI_CDS3081	COG1028	Short-chain dehydrogenase reductase Sdr
VITFI_CDS3082	COG0557	exoribonuclease II activity
VITFI_CDS3084	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
VITFI_CDS3085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VITFI_CDS3087	COG0511	ligase activity, forming carbon-carbon bonds
VITFI_CDS3088	COG0439	Biotin carboxylase
VITFI_CDS3089	COG2264	protein methyltransferase activity
VITFI_CDS3094	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VITFI_CDS3094	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VITFI_CDS3099	COG4137	Cytochrome C assembly protein
VITFI_CDS3100	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VITFI_CDS3102	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VITFI_CDS3104	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
VITFI_CDS3105	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
VITFI_CDS3106	COG2890	protein-(glutamine-N5) methyltransferase activity
VITFI_CDS3107	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VITFI_CDS3109	COG0741	lytic transglycosylase activity
VITFI_CDS3110	COG0442	prolyl-tRNA aminoacylation
VITFI_CDS3111	COG0494	nUDIX hydrolase
VITFI_CDS3112	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
VITFI_CDS3113	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VITFI_CDS3114	COG0211	Belongs to the bacterial ribosomal protein bL27 family
VITFI_CDS3115	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VITFI_CDS3116	COG0142	geranyltranstransferase activity
VITFI_CDS3120	COG0237	dephospho-CoA kinase activity
VITFI_CDS3121	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
VITFI_CDS3124	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VITFI_CDS3125	COG0181	hydroxymethylbilane synthase activity
VITFI_CDS3129	COG0183	Belongs to the thiolase family
VITFI_CDS3132	COG1024	Enoyl-CoA hydratase
VITFI_CDS3137	COG0411	ABC transporter
VITFI_CDS3138	COG0410	ABC transporter
VITFI_CDS3139	COG1960	acyl-CoA dehydrogenase activity
VITFI_CDS3142	COG3344	reverse transcriptase
VITFI_CDS3146	COG4676	Protein conserved in bacteria
VITFI_CDS3148	COG2828	Protein conserved in bacteria
VITFI_CDS3150	COG2733	membrane
VITFI_CDS3151	COG3162	membrane
VITFI_CDS3152	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VITFI_CDS3176	COG4773	Receptor
VITFI_CDS3177	COG0735	belongs to the Fur family
VITFI_CDS3182	COG3128	pkhd-type hydroxylase
VITFI_CDS3189	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VITFI_CDS3195	COG0012	GTP binding
VITFI_CDS3205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VITFI_CDS3206	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VITFI_CDS3211	COG1819	glycosyl
VITFI_CDS3226	COG0667	Aldo Keto reductase
VITFI_CDS3233	COG2124	cytochrome p450
VITFI_CDS3236	COG5002	protein histidine kinase activity
VITFI_CDS3236	COG0784	Response regulator, receiver
VITFI_CDS3236	COG2205	protein histidine kinase activity
VITFI_CDS3257	COG2918	glutathione biosynthetic process
VITFI_CDS3259	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VITFI_CDS3261	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VITFI_CDS3262	COG0765	amino acid transport
VITFI_CDS3263	COG0765	amino acid transport
VITFI_CDS3264	COG1126	abc transporter atp-binding protein
VITFI_CDS3274	COG0277	FAD linked oxidase domain protein
VITFI_CDS3276	COG1192	Involved in chromosome partitioning
VITFI_CDS3280	COG1309	transcriptional regulator
VITFI_CDS3283	COG1192	Involved in chromosome partitioning
VITFI_CDS3284	COG1475	DNA binding
VITFI_CDS3286	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VITFI_CDS3287	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VITFI_CDS3288	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VITFI_CDS3289	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
VITFI_CDS3293	COG2070	2-Nitropropane dioxygenase
VITFI_CDS3294	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VITFI_CDS3297	COG3384	dioxygenase
VITFI_CDS3298	COG1012	belongs to the aldehyde dehydrogenase family
VITFI_CDS3304	COG1846	Transcriptional regulator
VITFI_CDS3306	COG0033	Phosphoglucomutase
VITFI_CDS3311	COG1797	cobyrinic acid a,c-diamide synthase activity
VITFI_CDS3315	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
VITFI_CDS3316	COG3411	Ferredoxin
VITFI_CDS3318	COG0778	Nitroreductase
VITFI_CDS3322	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
VITFI_CDS3327	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VITFI_CDS3328	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
VITFI_CDS3330	COG0583	DNA-binding transcription factor activity
VITFI_CDS3332	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
VITFI_CDS3334	COG1120	ATPase activity
VITFI_CDS3335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VITFI_CDS3337	COG4206	TonB-dependent receptor
VITFI_CDS3339	COG2204	response regulator
VITFI_CDS3341	COG1858	cytochrome C peroxidase
VITFI_CDS3345	COG0820	rRNA (adenine-C2-)-methyltransferase activity
VITFI_CDS3348	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VITFI_CDS3351	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
VITFI_CDS3352	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
VITFI_CDS3357	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VITFI_CDS3358	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
VITFI_CDS3362	COG3181	Tripartite tricarboxylate transporter family receptor
VITFI_CDS3365	COG0420	3'-5' exonuclease activity
VITFI_CDS3369	COG2843	Capsule synthesis protein
VITFI_CDS3374	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VITFI_CDS3380	COG2337	Toxic component of a toxin-antitoxin (TA) module
VITFI_CDS3381	COG0346	lactoylglutathione lyase activity
VITFI_CDS3382	COG2119	membrane
VITFI_CDS3384	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VITFI_CDS3395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
VITFI_CDS3397	COG0484	heat shock protein binding
VITFI_CDS3399	COG2199	diguanylate cyclase activity
VITFI_CDS3399	COG2203	Gaf domain
VITFI_CDS3400	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
VITFI_CDS3400	COG2755	lipolytic protein G-D-S-L family
VITFI_CDS3403	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VITFI_CDS3404	COG0235	Class ii aldolase
VITFI_CDS3405	COG3971	2-oxopent-4-enoate hydratase activity
VITFI_CDS3407	COG0745	RESPONSE REGULATOR receiver
VITFI_CDS3408	COG2205	protein histidine kinase activity
VITFI_CDS3411	COG3550	peptidyl-serine autophosphorylation
VITFI_CDS3415	COG2030	dehydratase
VITFI_CDS3415	COG1012	belongs to the aldehyde dehydrogenase family
VITFI_CDS3417	COG0183	Belongs to the thiolase family
VITFI_CDS3419	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VITFI_CDS3420	COG2151	metal-sulfur cluster biosynthetic enzyme
VITFI_CDS3421	COG3396	Phenylacetate-CoA oxygenase
VITFI_CDS3422	COG3460	Phenylacetate-CoA oxygenase
VITFI_CDS3423	COG3396	Phenylacetate-CoA oxygenase
VITFI_CDS3425	COG2050	protein possibly involved in aromatic compounds catabolism
VITFI_CDS3426	COG1250	3-hydroxyacyl-CoA dehydrogenase
VITFI_CDS3427	COG1024	Enoyl-CoA hydratase
VITFI_CDS3430	COG1024	Enoyl-CoA hydratase
VITFI_CDS3432	COG0583	DNA-binding transcription factor activity
VITFI_CDS3437	COG4999	Histidine kinase
VITFI_CDS3437	COG3850	Histidine kinase
VITFI_CDS3437	COG3437	response regulator, receiver
VITFI_CDS3437	COG2205	protein histidine kinase activity
VITFI_CDS3441	COG0642	Histidine kinase
VITFI_CDS3442	COG0745	RESPONSE REGULATOR receiver
VITFI_CDS3445	COG3706	GGDEF domain
VITFI_CDS3453	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VITFI_CDS3454	COG1538	Outer membrane efflux protein
VITFI_CDS3456	COG0247	lactate metabolic process
VITFI_CDS3457	COG0277	FAD linked oxidase domain protein
VITFI_CDS3458	COG0277	FAD linked oxidase domain protein
VITFI_CDS3461	COG2267	carboxylic ester hydrolase activity
VITFI_CDS3467	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VITFI_CDS3468	COG1138	Cytochrome C-type biogenesis protein
VITFI_CDS3471	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VITFI_CDS3473	COG4133	protoheme IX ABC transporter activity
VITFI_CDS3476	COG0243	molybdopterin cofactor binding
VITFI_CDS3477	COG0437	4 iron, 4 sulfur cluster binding
VITFI_CDS3478	COG0348	domain, Protein
VITFI_CDS3490	COG0688	phosphatidylethanolamine metabolic process
VITFI_CDS3492	COG2203	Gaf domain
VITFI_CDS3492	COG2200	EAL domain
VITFI_CDS3492	COG2199	diguanylate cyclase activity
VITFI_CDS3495	COG2268	Band 7 protein
VITFI_CDS3496	COG1585	Membrane protein implicated in regulation of membrane protease activity
VITFI_CDS3499	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VITFI_CDS3502	COG3384	dioxygenase
VITFI_CDS3503	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VITFI_CDS3531	COG3077	Addiction module antitoxin, RelB DinJ family
VITFI_CDS3532	COG3041	Addiction module toxin RelE StbE family
VITFI_CDS3544	COG1136	(ABC) transporter
VITFI_CDS3546	COG1538	Outer membrane efflux protein
VITFI_CDS3547	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs