locus-tag	class	description
VMUT_0001	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
VMUT_0004	ENOG4105CHM	Aminotransferase
VMUT_0006	ENOG4108A04	Beta-lactamase
VMUT_0009	ENOG4105ETS	cytosine purines uracil thiamine allantoin
VMUT_0017	ENOG4105E39	Enoyl-CoA hydratase
VMUT_0022	ENOG4107TE1	transport protein
VMUT_0024	ENOG4105CEY	Amp-dependent synthetase and ligase
VMUT_0025	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
VMUT_0027	ENOG4105C1G	acyl-Coa dehydrogenase
VMUT_0028	ENOG4105CEY	Amp-dependent synthetase and ligase
VMUT_0032	ENOG4105DQU	oxidoreductase, subunit beta
VMUT_0033	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
VMUT_0036	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
VMUT_0037	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
VMUT_0039	ENOG410842T	Pterin carbinolamine dehydratase
VMUT_0056	ENOG4107QTZ	amino acid
VMUT_0059	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
VMUT_0060	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
VMUT_0078	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
VMUT_0080	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
VMUT_0081	ENOG4108JQ7	(ABC) transporter
VMUT_0084	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
VMUT_0086	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
VMUT_0089	ENOG4105CD8	aminopeptidase N
VMUT_0090	ENOG4107Y49	methyltransferase
VMUT_0092	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
VMUT_0095	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
VMUT_0096	ENOG4107TRG	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
VMUT_0098	ENOG4108RVA	ribokinase
VMUT_0104	ENOG41076HS	cation diffusion facilitator family transporter
VMUT_0107	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
VMUT_0109	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
VMUT_0115	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
VMUT_0116	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
VMUT_0117	ENOG4105C54	Major Facilitator superfamily
VMUT_0118	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
VMUT_0119	ENOG4105E45	Histidinol-phosphate aminotransferase
VMUT_0127	ENOG4105C1G	acyl-Coa dehydrogenase
VMUT_0131	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
VMUT_0133	ENOG4108J9M	Transporter
VMUT_0136	ENOG4105C5S	asparaginyl-tRNA synthetase
VMUT_0141	ENOG4105DJB	Major Facilitator Superfamily
VMUT_0144	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
VMUT_0146	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
VMUT_0147	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
VMUT_0149	ENOG4105CZA	synthase
VMUT_0151	ENOG4105DQU	oxidoreductase, subunit beta
VMUT_0152	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
VMUT_0175	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
VMUT_0177	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
VMUT_0181	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
VMUT_0189	ENOG4105DC7	peptidase M24
VMUT_0190	ENOG4105DCI	Phosphohydrolase
VMUT_0192	ENOG4105C31	Tryptophanyl-tRNA synthetase
VMUT_0195	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
VMUT_0196	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
VMUT_0199	ENOG4105D44	asparaginase
VMUT_0200	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
VMUT_0205	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
VMUT_0206	ENOG4105VG1	fes assembly suf system protein
VMUT_0209	ENOG4105CIF	Ornithine Cyclodeaminase
VMUT_0213	ENOG4105CAS	nag kinase
VMUT_0221	ENOG4107R34	abc transporter permease protein
VMUT_0222	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
VMUT_0234	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
VMUT_0240	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
VMUT_0242	ENOG4105EFZ	amidohydrolase
VMUT_0246	ENOG4105D1Z	hydroxypyruvate reductase
VMUT_0263	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VMUT_0266	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
VMUT_0267	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
VMUT_0274	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
VMUT_0275	ENOG4105CQ2	DNA polymerase
VMUT_0277	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
VMUT_0279	ENOG4105D82	Glutamate dehydrogenase
VMUT_0280	ENOG4105CNW	domain protein
VMUT_0282	ENOG4105BZN	citrate synthase
VMUT_0287	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
VMUT_0292	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
VMUT_0295	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
VMUT_0297	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
VMUT_0305	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
VMUT_0306	ENOG4105DHP	deoxycytidine triphosphate deaminase
VMUT_0309	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
VMUT_0314	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
VMUT_0316	ENOG4107EPV	Aminotransferase class V
VMUT_0317	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
VMUT_0318	ENOG4105DXD	2-methylcitrate dehydratase
VMUT_0319	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
VMUT_0323	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
VMUT_0326	ENOG4105CMG	Carbohydrate kinase
VMUT_0327	ENOG4105DY8	decarboxylase
VMUT_0330	ENOG4108IUW	ABC transporter
VMUT_0333	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
VMUT_0335	ENOG4105CR4	methylisocitrate lyase
VMUT_0336	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
VMUT_0338	ENOG41066FR	extracellular solute-binding protein
VMUT_0343	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
VMUT_0344	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
VMUT_0345	ENOG4105CYW	agmatinase
VMUT_0347	ENOG4105EJ5	oxidoreductase gamma subunit
VMUT_0349	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
VMUT_0350	ENOG4105DDK	oxidoreductase, beta subunit
VMUT_0357	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
VMUT_0362	ENOG4105CEY	Amp-dependent synthetase and ligase
VMUT_0363	ENOG4105CGK	Exodeoxyribonuclease III
VMUT_0367	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
VMUT_0369	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
VMUT_0371	ENOG4108V1U	phospholipid-binding protein
VMUT_0372	ENOG4107TIA	phenylalanyl-tRNA synthetase (beta subunit)
VMUT_0381	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
VMUT_0382	ENOG4105BZJ	Electron transfer flavoprotein
VMUT_0383	ENOG4105C10	Electron transfer flavoprotein
VMUT_0384	ENOG4105DF6	Fe-S oxidoreductase
VMUT_0385	ENOG4105D9P	serine threonine protein kinase
VMUT_0388	ENOG4105CN9	Peptidase m42 family protein
VMUT_0390	ENOG4105BZA	Phosphoglycerate kinase
VMUT_0394	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
VMUT_0396	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
VMUT_0398	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
VMUT_0406	ENOG41067TZ	transcriptional regulator, MarR family
VMUT_0409	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
VMUT_0410	ENOG4105D56	permease protein
VMUT_0412	ENOG4108IUK	alpha amylase, catalytic
VMUT_0414	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
VMUT_0419	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
VMUT_0420	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
VMUT_0428	ENOG4105DBV	ornithine carbamoyltransferase
VMUT_0430	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
VMUT_0432	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
VMUT_0433	ENOG4105C4K	Nad synthetase
VMUT_0434	ENOG4108HMX	isocitrate dehydrogenase (NADP)
VMUT_0437	ENOG4105C5I	Dehydrogenase
VMUT_0438	ENOG4105P8F	nudix hydrolase
VMUT_0441	ENOG4105CPQ	Dehydrogenase
VMUT_0443	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
VMUT_0444	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
VMUT_0445	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
VMUT_0446	ENOG4107QSE	Dipeptidase
VMUT_0447	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
VMUT_0454	ENOG4108JQ7	(ABC) transporter
VMUT_0457	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
VMUT_0487	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
VMUT_0488	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
VMUT_0492	ENOG4107RIQ	Sulfate adenylate transferase
VMUT_0502	ENOG4105PJW	Sulfite reductase dissimilatory-type beta subunit
VMUT_0504	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
VMUT_0508	ENOG4105CV8	reductase
VMUT_0516	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
VMUT_0519	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
VMUT_0520	ENOG4105C3M	thioredoxin reductase
VMUT_0523	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
VMUT_0525	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
VMUT_0528	ENOG4105CAY	ferredoxin--nadp reductase
VMUT_0529	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
VMUT_0530	ENOG4107QTF	adenylosuccinate lyase
VMUT_0536	ENOG4105C01	Dihydroxy-acid dehydratase
VMUT_0537	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
VMUT_0538	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
VMUT_0539	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
VMUT_0542	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
VMUT_0543	ENOG4105CQB	FAD linked oxidase domain protein
VMUT_0548	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
VMUT_0557	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
VMUT_0560	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
VMUT_0567	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
VMUT_0571	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
VMUT_0574	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
VMUT_0576	ENOG4105D3R	alkyl hydroperoxide reductase
VMUT_0586	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
VMUT_0590	ENOG4105E2R	ROK family
VMUT_0592	ENOG4107YZX	Universal stress protein
VMUT_0595	ENOG4105KG3	cytidine deaminase
VMUT_0600	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
VMUT_0605	ENOG4105C26	Dehydrogenase
VMUT_0606	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
VMUT_0607	ENOG4107GFK	fumarate
VMUT_0610	ENOG4105CPQ	Dehydrogenase
VMUT_0612	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
VMUT_0613	ENOG4107TE1	transport protein
VMUT_0615	ENOG4105C5S	asparaginyl-tRNA synthetase
VMUT_0617	ENOG4108IUW	ABC transporter
VMUT_0624	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
VMUT_0625	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
VMUT_0627	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VMUT_0629	ENOG4105C0H	protease
VMUT_0632	ENOG4105BZJ	Electron transfer flavoprotein
VMUT_0633	ENOG4105C10	Electron transfer flavoprotein
VMUT_0634	ENOG4105DF6	Fe-S oxidoreductase
VMUT_0635	ENOG4105EWK	phytoene
VMUT_0637	ENOG4105DQU	oxidoreductase, subunit beta
VMUT_0638	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
VMUT_0643	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
VMUT_0646	ENOG4105CHU	acetyl-coa acetyltransferase
VMUT_0647	ENOG4105G5W	regulator Fur family
VMUT_0648	ENOG4108RAC	Rubrerythrin
VMUT_0650	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
VMUT_0653	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
VMUT_0655	ENOG4105IU0	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
VMUT_0657	ENOG4105EN6	Membrane
VMUT_0658	ENOG4105EQW	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
VMUT_0662	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
VMUT_0666	ENOG4105WCJ	ec 1.1.1.193
VMUT_0679	ENOG4105CEY	Amp-dependent synthetase and ligase
VMUT_0680	ENOG4105C1G	acyl-Coa dehydrogenase
VMUT_0682	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
VMUT_0683	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
VMUT_0688	ENOG4108YZ4	nudix hydrolase
VMUT_0689	ENOG4105CSM	endonuclease III
VMUT_0690	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
VMUT_0691	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
VMUT_0694	ENOG4107SQD	Transcriptional regulator, GntR family
VMUT_0696	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
VMUT_0707	ENOG4105F8V	Hydrolase, tatD family
VMUT_0713	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
VMUT_0714	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
VMUT_0715	ENOG4105CXK	mandelate racemase muconate lactonizing
VMUT_0723	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
VMUT_0724	ENOG4105K63	Thioredoxin
VMUT_0725	ENOG4108JPW	Aminotransferase
VMUT_0726	ENOG4105CD5	CoA-binding domain protein
VMUT_0727	ENOG4105CD5	CoA-binding domain protein
VMUT_0728	ENOG4105D0M	Protease HtpX homolog
VMUT_0737	ENOG41086CI	Bifunctional phosphoglucose phosphomannose isomerase
VMUT_0738	ENOG4105CM2	brancheD-chain amino acid aminotransferase
VMUT_0739	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
VMUT_0743	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
VMUT_0747	ENOG4105DWF	phosphomethylpyrimidine kinase
VMUT_0755	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
VMUT_0756	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
VMUT_0760	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
VMUT_0761	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
VMUT_0775	ENOG4105CI2	imidazolone-5-propionate hydrolase
VMUT_0776	ENOG4105CX6	glutaminyL-tRNA synthetase
VMUT_0778	ENOG4105CHM	Aminotransferase
VMUT_0780	ENOG4105E66	phosphoriboisomerase A
VMUT_0781	ENOG4105EEI	dihydropteroate synthase
VMUT_0784	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
VMUT_0785	ENOG4105CYW	agmatinase
VMUT_0788	ENOG4105D63	family UPF0324
VMUT_0791	ENOG4105CGP	Urocanate hydratase
VMUT_0797	ENOG4105C1G	acyl-Coa dehydrogenase
VMUT_0802	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
VMUT_0803	ENOG4105ETU	transcriptional activator (TenA
VMUT_0804	ENOG4105CHR	reductase
VMUT_0805	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
VMUT_0808	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
VMUT_0809	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
VMUT_0815	ENOG4108IEG	Formate dehydrogenase Alpha subunit
VMUT_0816	ENOG4107QIZ	NADH dehydrogenase
VMUT_0819	ENOG4108M14	stage v sporulation protein t
VMUT_0820	ENOG4105HDK	L-asparaginase
VMUT_0826	ENOG4105CHR	reductase
VMUT_0829	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
VMUT_0830	ENOG4105D3W	isochorismatase
VMUT_0832	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
VMUT_0842	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
VMUT_0856	ENOG4105CXK	mandelate racemase muconate lactonizing
VMUT_0857	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
VMUT_0858	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
VMUT_0865	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
VMUT_0872	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
VMUT_0876	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
VMUT_0883	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
VMUT_0891	ENOG4105CI0	Citrate lyase
VMUT_0893	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
VMUT_0894	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
VMUT_0896	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
VMUT_0903	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
VMUT_0904	ENOG4105C5X	domain protein
VMUT_0906	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
VMUT_0910	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
VMUT_0914	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
VMUT_0918	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
VMUT_0920	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
VMUT_0921	ENOG4105E0A	ABC, transporter
VMUT_0922	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
VMUT_0924	ENOG4105D5P	Methylmalonyl-coA mutase
VMUT_0931	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
VMUT_0933	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
VMUT_0934	ENOG4107R56	PP-loop domain protein
VMUT_0935	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
VMUT_0938	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
VMUT_0941	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
VMUT_0945	ENOG4107QTZ	amino acid
VMUT_0946	ENOG4107QTZ	amino acid
VMUT_0957	ENOG4105CSH	Transporter
VMUT_0960	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
VMUT_0963	ENOG4108UJD	30S ribosomal protein S9
VMUT_0965	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
VMUT_0972	ENOG4105CHR	reductase
VMUT_0976	ENOG4108Z0R	Transferase
VMUT_0978	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
VMUT_0979	ENOG4105CN9	Peptidase m42 family protein
VMUT_0980	ENOG4105C7N	Xanthine uracil vitamin C permease
VMUT_1033	ENOG4105BZ1	(ABC) transporter
VMUT_1035	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
VMUT_1051	ENOG4107S6X	Glycosyl transferase, family 2
VMUT_1054	ENOG4108SHN	Glycosyl transferase, family 2
VMUT_1070	ENOG4105CBG	Sulfatase
VMUT_1076	ENOG4105K64	Glycosyl transferase, family 2
VMUT_1079	ENOG4106WTF	Glycosyl transferase, family 2
VMUT_1090	ENOG4105CPK	Glycosyl transferase (Group 1
VMUT_1092	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
VMUT_1093	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
VMUT_1094	ENOG4106WTF	Glycosyl transferase, family 2
VMUT_1095	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
VMUT_1110	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
VMUT_1112	ENOG4107R0E	Glycosyl transferase, family 2
VMUT_1131	ENOG4105EPH	radical SAM domain protein
VMUT_1132	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
VMUT_1133	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
VMUT_1134	ENOG41090P5	ferredoxin-like protein
VMUT_1135	ENOG4105BZJ	Electron transfer flavoprotein
VMUT_1136	ENOG4105C10	Electron transfer flavoprotein
VMUT_1150	ENOG4105DTQ	mandelate racemase muconate lactonizing
VMUT_1151	ENOG4105CTX	dehydratase
VMUT_1153	ENOG4105DRR	Transcriptional regulator, GntR family
VMUT_1154	ENOG4105CSH	Transporter
VMUT_1156	ENOG4105EFZ	amidohydrolase
VMUT_1158	ENOG4105CSH	Transporter
VMUT_1161	ENOG4107QKR	Dehydrogenase
VMUT_1165	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
VMUT_1169	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
VMUT_1170	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
VMUT_1171	ENOG4105CYW	agmatinase
VMUT_1177	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
VMUT_1178	ENOG4105C26	Dehydrogenase
VMUT_1179	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
VMUT_1197	ENOG4105WGB	oxidoreductase, delta subunit
VMUT_1198	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
VMUT_1199	ENOG4105DDK	oxidoreductase, beta subunit
VMUT_1201	ENOG4105CQB	FAD linked oxidase domain protein
VMUT_1202	ENOG4105CQB	FAD linked oxidase domain protein
VMUT_1204	ENOG4105DAA	L-lactate
VMUT_1205	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
VMUT_1213	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
VMUT_1220	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
VMUT_1225	ENOG4105CUT	histidyl-tRNA synthetase
VMUT_1232	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
VMUT_1234	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
VMUT_1235	ENOG4105CPQ	Dehydrogenase
VMUT_1238	ENOG4105CXK	mandelate racemase muconate lactonizing
VMUT_1241	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
VMUT_1242	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
VMUT_1243	ENOG4108J5G	6-phosphogluconate dehydrogenase
VMUT_1245	ENOG4107QNK	)-transporter
VMUT_1248	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
VMUT_1249	ENOG4105C2J	ABC transporter
VMUT_1251	ENOG4105XN3	extracellular solute-binding protein family 1
VMUT_1253	ENOG4105CEV	competence damage-inducible protein
VMUT_1254	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
VMUT_1255	ENOG4105CTX	dehydratase
VMUT_1260	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
VMUT_1263	ENOG41061GT	Aldolase
VMUT_1266	ENOG4105C8N	cysteinyl-tRNA synthetase
VMUT_1268	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
VMUT_1271	ENOG41082SA	50s ribosomal protein l29
VMUT_1272	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
VMUT_1280	ENOG4105CBC	glutamate synthase
VMUT_1281	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
VMUT_1282	ENOG4105CEY	Amp-dependent synthetase and ligase
VMUT_1283	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
VMUT_1293	ENOG4108V1U	phospholipid-binding protein
VMUT_1294	ENOG4105C01	Dihydroxy-acid dehydratase
VMUT_1296	ENOG4105EUJ	GTP cyclohydrolase i
VMUT_1298	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
VMUT_1299	ENOG4105EYF	MMPL domain protein
VMUT_1301	ENOG4105D7N	magnesium and cobalt transport protein CorA
VMUT_1303	ENOG4105C7W	Xanthine dehydrogenase
VMUT_1305	ENOG4105C54	Major Facilitator superfamily
VMUT_1309	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
VMUT_1310	ENOG4105CY0	Metallo-Beta-Lactamase
VMUT_1311	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
VMUT_1312	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
VMUT_1317	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
VMUT_1318	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
VMUT_1323	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
VMUT_1325	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
VMUT_1334	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
VMUT_1336	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
VMUT_1339	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
VMUT_1347	ENOG4107QNK	)-transporter
VMUT_1348	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VMUT_1352	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
VMUT_1354	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
VMUT_1357	ENOG4105DVY	radical SAM domain protein
VMUT_1358	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
VMUT_1360	ENOG4107R3A	FAD linked oxidase domain protein
VMUT_1363	ENOG41080HI	glycine oxidase
VMUT_1369	ENOG4105C1G	acyl-Coa dehydrogenase
VMUT_1372	ENOG4105C7K	acetolactate synthase
VMUT_1373	ENOG4108JQ1	Dehydrogenase
VMUT_1375	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
VMUT_1376	ENOG4105CHU	acetyl-coa acetyltransferase
VMUT_1378	ENOG4105CGU	Enoyl-CoA hydratase
VMUT_1381	ENOG4105CEY	Amp-dependent synthetase and ligase
VMUT_1387	ENOG4105ECY	inositol monophosphatase
VMUT_1405	ENOG4105Q33	Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency
VMUT_1409	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
VMUT_1411	ENOG4105DIW	FeS assembly protein SUFB
VMUT_1412	ENOG4105DIW	FeS assembly protein SUFB
VMUT_1413	ENOG4105C3K	feS assembly ATPase SufC
VMUT_1414	ENOG4105CD3	dihydroorotase
VMUT_1417	ENOG4105DDQ	anthranilate synthase
VMUT_1418	ENOG4105CRQ	synthase (Component I)
VMUT_1419	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
VMUT_1420	ENOG4108I0Q	anthranilate phosphoribosyltransferase
VMUT_1421	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
VMUT_1422	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
VMUT_1425	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
VMUT_1426	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
VMUT_1429	ENOG4105E2X	shikimate dehydrogenase
VMUT_1430	ENOG4105D49	3-dehydroquinate synthase
VMUT_1431	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
VMUT_1432	ENOG4105CQC	Prephenate dehydratase
VMUT_1434	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
VMUT_1436	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
VMUT_1437	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
VMUT_1438	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
VMUT_1440	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
VMUT_1450	ENOG4105C2X	Arabinose 5-phosphate isomerase
VMUT_1451	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
VMUT_1453	ENOG4107VRP	DNA repair exonuclease
VMUT_1454	ENOG4105EYH	Exonuclease
VMUT_1456	ENOG4105CD5	CoA-binding domain protein
VMUT_1463	ENOG4105CJ1	ABC, transporter
VMUT_1465	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
VMUT_1469	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
VMUT_1470	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
VMUT_1498	ENOG4107QRT	dEAD DEAH box helicase
VMUT_1504	ENOG4107QJE	Chromosome Partitioning Protein
VMUT_1507	ENOG4105KZX	Pterin carbinolamine dehydratase
VMUT_1512	ENOG4105CSH	Transporter
VMUT_1517	ENOG4105CQC	Prephenate dehydratase
VMUT_1518	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
VMUT_1520	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
VMUT_1521	ENOG4105C7K	acetolactate synthase
VMUT_1523	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
VMUT_1524	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
VMUT_1526	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
VMUT_1527	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
VMUT_1528	ENOG4105CFH	Aspartokinase
VMUT_1529	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
VMUT_1530	ENOG4105D6E	homoserine dehydrogenase
VMUT_1532	ENOG4105CSH	Transporter
VMUT_1533	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
VMUT_1535	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
VMUT_1536	ENOG4107SDT	Homocitrate synthase
VMUT_1538	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
VMUT_1540	ENOG4107U4Q	acetylglutamate kinase
VMUT_1541	ENOG4105CHM	Aminotransferase
VMUT_1542	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
VMUT_1543	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
VMUT_1544	ENOG4105CH7	arginosuccinase
VMUT_1547	ENOG4105CDH	Citrulline--aspartate ligase
VMUT_1550	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
VMUT_1551	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
VMUT_1554	ENOG4105CSH	Transporter
VMUT_1556	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
VMUT_1561	ENOG4105C8T	Leucyl-tRNA synthetase
VMUT_1568	ENOG4105EM7	Selenocysteine-specific translation elongation factor
VMUT_1570	ENOG4105C5F	glutamine synthetase
VMUT_1572	ENOG4105K63	Thioredoxin
VMUT_1576	ENOG4108Z4J	Cytidine monophosphate kinase
VMUT_1579	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
VMUT_1580	ENOG4105CE9	30S ribosomal protein S2
VMUT_1581	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
VMUT_1584	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
VMUT_1588	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
VMUT_1596	ENOG4105D06	uba thif-type nad fad binding protein
VMUT_1598	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
VMUT_1599	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
VMUT_1601	ENOG4106YT9	Enoyl-CoA hydratase
VMUT_1607	ENOG4105M7V	2'-5' rna ligase
VMUT_1616	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
VMUT_1623	ENOG4108I62	cina-like protein
VMUT_1646	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
VMUT_1650	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
VMUT_1656	ENOG4107XGZ	Hydrolase
VMUT_1659	ENOG4105NBF	ammecr1 domain protein
VMUT_1663	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
VMUT_1664	ENOG4107Y70	Heat shock protein
VMUT_1666	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
VMUT_1675	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
VMUT_1676	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
VMUT_1677	ENOG4105CTD	carboxy-peptidase
VMUT_1679	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
VMUT_1680	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
VMUT_1681	ENOG4108Z1Z	gCN5-related N-acetyltransferase
VMUT_1690	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
VMUT_1691	ENOG4108S4H	thioesterase Superfamily protein
VMUT_1695	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
VMUT_1723	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
VMUT_1724	ENOG41082CS	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
VMUT_1726	ENOG4105DGU	Histone deacetylase
VMUT_1734	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
VMUT_1737	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VMUT_1739	ENOG4105D7V	transposase
VMUT_1751	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
VMUT_1760	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
VMUT_1762	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
VMUT_1771	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
VMUT_1774	ENOG4107QRT	dEAD DEAH box helicase
VMUT_1780	ENOG4105C6K	Malic enzyme
VMUT_1782	ENOG4108XM1	transcriptional regulator AsnC family
VMUT_1783	ENOG4105CQ2	DNA polymerase
VMUT_1786	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
VMUT_1787	ENOG4105C3I	Nad-dependent epimerase dehydratase
VMUT_1788	ENOG4105C22	threonyL-tRNA synthetase
VMUT_1791	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
VMUT_1812	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
VMUT_1814	ENOG4108JPZ	Monovalent cation H antiporter subunit D
VMUT_1816	ENOG4107QR9	Iron-sulfur cluster binding protein
VMUT_1818	ENOG4105C7B	Threonine dehydratase
VMUT_1819	ENOG4105KME	endoribonuclease L-psp
VMUT_1822	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
VMUT_1829	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
VMUT_1831	ENOG4105C5S	asparaginyl-tRNA synthetase
VMUT_1836	ENOG4105CUB	amino acid
VMUT_1837	ENOG4105EDK	PfkB domain protein
VMUT_1838	ENOG4105CEY	Amp-dependent synthetase and ligase
VMUT_1839	ENOG4107SVH	Potassium channel protein
VMUT_1844	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
VMUT_1848	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
VMUT_1852	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
VMUT_1853	ENOG4105C1V	Peptidase, M16
VMUT_1854	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
VMUT_1862	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
VMUT_1867	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
VMUT_1868	ENOG41080HJ	6-phospho 3-hexuloisomerase
VMUT_1869	ENOG4105D5M	phosphate starvation-inducible protein
VMUT_1871	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VMUT_1880	ENOG4105C28	cystathionine
VMUT_1899	ENOG4105DQU	oxidoreductase, subunit beta
VMUT_1930	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
VMUT_1931	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
VMUT_1933	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
VMUT_1934	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
VMUT_1935	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
VMUT_1938	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
VMUT_1939	ENOG4105C8V	SAICAR synthetase
VMUT_1940	ENOG4105C12	Phosphoribosylglycinamide synthetase
VMUT_1941	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
VMUT_1942	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
VMUT_1946	ENOG4107QV3	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
VMUT_1959	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
VMUT_1961	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
VMUT_1962	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
VMUT_1966	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
VMUT_1967	ENOG4108IJ9	(ABC) transporter
VMUT_1969	ENOG4105CXT	aspartate transcarbamylase
VMUT_1970	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
VMUT_1971	ENOG4108DJF	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
VMUT_1972	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
VMUT_1977	ENOG4105C5I	Dehydrogenase
VMUT_1981	ENOG4108I5U	Uridine phosphorylase
VMUT_1986	ENOG4105ETU	transcriptional activator (TenA
VMUT_1989	ENOG4105PDP	Short chain dehydrogenase
VMUT_1995	ENOG4105C5X	domain protein
VMUT_2007	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VMUT_2013	ENOG4108Q5Y	Membrane
VMUT_2035	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
VMUT_2036	ENOG4105EYH	Exonuclease
VMUT_2047	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
VMUT_2049	ENOG4108R6G	acetyltransferase
VMUT_2050	ENOG4105E3H	phosphoglycerate mutase
VMUT_2051	ENOG4105VF7	tolerance protein
VMUT_2052	ENOG4108FN7	Aldo keto reductase
VMUT_2053	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
VMUT_2054	ENOG4105D64	Mechanosensitive ion channel
VMUT_2055	ENOG4105C3G	gtp-binding protein
VMUT_2056	ENOG4105C75	arginyL-tRNA synthetase
VMUT_2058	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
VMUT_2059	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
VMUT_2060	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
VMUT_2061	ENOG4105XPM	ribosomal protein
VMUT_2065	ENOG4105D1H	recombination factor protein RarA
VMUT_2071	ENOG4107RGD	Major Facilitator superfamily
VMUT_2074	ENOG4105CPC	Aldo Keto reductase
VMUT_2076	ENOG41084XP	SirA-like domain-containing protein
VMUT_2079	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
VMUT_2081	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
VMUT_2083	ENOG4108JJB	ABC transporter
VMUT_2084	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
VMUT_2092	ENOG4105CP7	Triose-phosphate isomerase
VMUT_2093	ENOG4107QM5	aconitate hydratase
VMUT_2097	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
VMUT_2101	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
VMUT_2104	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
VMUT_2105	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
VMUT_2112	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
VMUT_2113	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
VMUT_2119	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
VMUT_2124	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
VMUT_2134	ENOG4107QTZ	amino acid
VMUT_2136	ENOG4105EW9	transcriptional regulator AsnC family
VMUT_2139	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
VMUT_2140	ENOG4105C6T	cysteine synthase
VMUT_2142	ENOG4108JPW	Aminotransferase
VMUT_2146	ENOG4105C4M	(Ubiquinol oxidase) subunit I
VMUT_2147	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
VMUT_2156	ENOG4105CEV	competence damage-inducible protein
VMUT_2159	ENOG4108JQ1	Dehydrogenase
VMUT_2176	ENOG4108R96	Methyltransferase, YaeB family
VMUT_2183	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
VMUT_2186	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
VMUT_2188	ENOG4105C3U	ABC transporter
VMUT_2190	ENOG4105DEF	Extracellular solute-binding protein, family 5
VMUT_2191	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
VMUT_2192	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
VMUT_2198	ENOG4105D52	delta-aminolevulinic acid dehydratase
VMUT_2199	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
VMUT_2202	ENOG4105D1F	ATP-binding protein
VMUT_2203	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
VMUT_2209	ENOG4105F1A	Pyruvate formate-lyase
VMUT_2213	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VMUT_2221	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
VMUT_2223	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
VMUT_2225	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VMUT_2234	ENOG4105I3N	Conserved Protein
VMUT_2237	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
VMUT_2247	ENOG41079KZ	Major Facilitator Superfamily
VMUT_2251	ENOG4105CUJ	penicillin amidase
VMUT_2252	ENOG4105CEY	Amp-dependent synthetase and ligase
VMUT_2254	ENOG4105CEY	Amp-dependent synthetase and ligase
VMUT_2259	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
VMUT_2260	ENOG4105CHR	reductase
VMUT_2263	ENOG4105E09	nadh pyrophosphatase
VMUT_2264	ENOG41079KZ	Major Facilitator Superfamily
VMUT_2265	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
VMUT_2267	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VMUT_2275	ENOG4107QTZ	amino acid
VMUT_2279	ENOG4105DA5	(ABC) transporter
VMUT_2286	ENOG4105CY0	Metallo-Beta-Lactamase
VMUT_2296	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
VMUT_2298	ENOG4105C1J	atp-dependent rna helicase
VMUT_2301	ENOG4108I5U	Uridine phosphorylase
VMUT_2304	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
VMUT_2307	ENOG4105C26	Dehydrogenase
VMUT_2313	ENOG4105CXK	mandelate racemase muconate lactonizing
VMUT_2322	ENOG4107NFR	Fructose-1,6-bisphosphatase
VMUT_2326	ENOG4105E50	uracil-dna glycosylase
VMUT_2327	ENOG4105C1G	acyl-Coa dehydrogenase
VMUT_2328	ENOG4105C1G	acyl-Coa dehydrogenase
VMUT_2331	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
VMUT_2334	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
VMUT_2341	ENOG4105CVN	desaturase
VMUT_2344	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)