VMUT_1056 fc7947bb044c1ded7c7bd8511ca9d359 709 SUPERFAMILY SSF51126 121 418 1.57E-17 T 23-10-2018 IPR011050 Pectin lyase fold/virulence factor VMUT_1056 fc7947bb044c1ded7c7bd8511ca9d359 709 SMART SM00710 502 529 8400.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat VMUT_1056 fc7947bb044c1ded7c7bd8511ca9d359 709 SMART SM00710 544 565 3600.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat VMUT_1056 fc7947bb044c1ded7c7bd8511ca9d359 709 SMART SM00710 445 466 1900.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat VMUT_1056 fc7947bb044c1ded7c7bd8511ca9d359 709 SMART SM00710 297 319 8800.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat VMUT_1056 fc7947bb044c1ded7c7bd8511ca9d359 709 SMART SM00710 202 237 2900.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat VMUT_1056 fc7947bb044c1ded7c7bd8511ca9d359 709 SMART SM00710 330 352 1000.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat VMUT_1056 fc7947bb044c1ded7c7bd8511ca9d359 709 SMART SM00710 354 375 620.0 T 23-10-2018 IPR006626 Parallel beta-helix repeat VMUT_1056 fc7947bb044c1ded7c7bd8511ca9d359 709 Gene3D G3DSA:2.160.20.10 120 423 1.4E-17 T 23-10-2018 IPR012334 Pectin lyase fold VMUT_1056 fc7947bb044c1ded7c7bd8511ca9d359 709 SUPERFAMILY SSF51126 383 620 7.54E-5 T 23-10-2018 IPR011050 Pectin lyase fold/virulence factor VMUT_0964 f3bc086a0f3b0d2246fb13a0c061d4b7 195 SUPERFAMILY SSF52161 28 166 1.57E-35 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 VMUT_0964 f3bc086a0f3b0d2246fb13a0c061d4b7 195 TIGRFAM TIGR01077 L13_A_E: ribosomal protein uL13 28 164 5.9E-44 T 23-10-2018 IPR005755 Ribosomal protein L13, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 VMUT_0964 f3bc086a0f3b0d2246fb13a0c061d4b7 195 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 27 160 20.016 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 VMUT_0964 f3bc086a0f3b0d2246fb13a0c061d4b7 195 ProSitePatterns PS00783 Ribosomal protein L13 signature. 107 130 - T 23-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 VMUT_0964 f3bc086a0f3b0d2246fb13a0c061d4b7 195 Gene3D G3DSA:3.90.1180.10 24 167 2.6E-44 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 VMUT_0964 f3bc086a0f3b0d2246fb13a0c061d4b7 195 PIRSF PIRSF002181 10 179 9.1E-37 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 VMUT_0964 f3bc086a0f3b0d2246fb13a0c061d4b7 195 Pfam PF00572 Ribosomal protein L13 51 131 1.3E-8 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 VMUT_0118 90abc64f7971df83ba86640dbb6d6460 524 PIRSF PIRSF000538 5 519 3.0E-168 T 23-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 VMUT_0118 90abc64f7971df83ba86640dbb6d6460 524 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 380 400 - T 23-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 VMUT_0118 90abc64f7971df83ba86640dbb6d6460 524 SUPERFAMILY SSF53067 273 514 2.59E-83 T 23-10-2018 VMUT_0118 90abc64f7971df83ba86640dbb6d6460 524 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 8 269 1.1E-71 T 23-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 VMUT_0118 90abc64f7971df83ba86640dbb6d6460 524 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 7 514 1.4E-201 T 23-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 VMUT_0118 90abc64f7971df83ba86640dbb6d6460 524 Gene3D G3DSA:3.30.420.40 3 270 5.2E-94 T 23-10-2018 VMUT_0118 90abc64f7971df83ba86640dbb6d6460 524 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 279 468 3.5E-58 T 23-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 VMUT_0118 90abc64f7971df83ba86640dbb6d6460 524 SUPERFAMILY SSF53067 7 270 5.12E-82 T 23-10-2018 VMUT_0118 90abc64f7971df83ba86640dbb6d6460 524 Gene3D G3DSA:3.30.420.40 272 518 1.5E-89 T 23-10-2018 VMUT_0118 90abc64f7971df83ba86640dbb6d6460 524 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 136 148 - T 23-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 VMUT_0118 90abc64f7971df83ba86640dbb6d6460 524 Hamap MF_00186 Glycerol kinase [glpK]. 5 515 55.106 T 23-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 VMUT_1214 a6e84682b7ca4253a7230bc10b11f369 132 SMART SM01376 69 132 1.2E-17 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 VMUT_1214 a6e84682b7ca4253a7230bc10b11f369 132 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 8 43 3.0E-6 T 23-10-2018 IPR013185 Translation elongation factor, KOW-like VMUT_1214 a6e84682b7ca4253a7230bc10b11f369 132 Gene3D G3DSA:2.40.50.140 69 132 9.0E-29 T 23-10-2018 VMUT_1214 a6e84682b7ca4253a7230bc10b11f369 132 PIRSF PIRSF003025 1 132 8.3E-44 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 VMUT_1214 a6e84682b7ca4253a7230bc10b11f369 132 Pfam PF01287 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold 70 132 6.3E-10 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 VMUT_1214 a6e84682b7ca4253a7230bc10b11f369 132 SUPERFAMILY SSF50104 1 77 4.36E-22 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily VMUT_1214 a6e84682b7ca4253a7230bc10b11f369 132 SUPERFAMILY SSF50249 69 131 3.34E-13 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold VMUT_1214 a6e84682b7ca4253a7230bc10b11f369 132 ProSitePatterns PS00302 Eukaryotic initiation factor 5A hypusine signature. 34 41 - T 23-10-2018 IPR019769 Translation elongation factor, IF5A, hypusine site GO:0003723|GO:0003746|GO:0043022|GO:0045901|GO:0045905 VMUT_1214 a6e84682b7ca4253a7230bc10b11f369 132 Gene3D G3DSA:2.30.30.30 1 68 6.3E-31 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 VMUT_1214 a6e84682b7ca4253a7230bc10b11f369 132 Hamap MF_00085 Translation initiation factor 5A [eif5a]. 2 131 31.835 T 23-10-2018 IPR022847 Translation elongation factor IF5A, archaeal VMUT_1214 a6e84682b7ca4253a7230bc10b11f369 132 TIGRFAM TIGR00037 eIF_5A: translation elongation factor IF5A 1 131 6.4E-39 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 VMUT_0567 520aed484d142aa9d128721d95147169 263 SUPERFAMILY SSF54862 1 205 1.15E-61 T 23-10-2018 VMUT_0567 520aed484d142aa9d128721d95147169 263 Gene3D G3DSA:3.30.70.20 1 248 4.5E-59 T 23-10-2018 VMUT_0567 520aed484d142aa9d128721d95147169 263 Pfam PF12800 4Fe-4S binding domain 11 24 0.32 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_0567 520aed484d142aa9d128721d95147169 263 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 110 121 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_0567 520aed484d142aa9d128721d95147169 263 Pfam PF13247 4Fe-4S dicluster domain 71 171 9.4E-21 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_0644 f99220fd7b77925e720d57d760b7991d 1312 SUPERFAMILY SSF55608 722 841 5.53E-17 T 23-10-2018 IPR027434 Homing endonuclease VMUT_0644 f99220fd7b77925e720d57d760b7991d 1312 PRINTS PR00379 Intein signature 547 560 4.5E-25 T 23-10-2018 IPR006142 Intein GO:0016539 VMUT_0644 f99220fd7b77925e720d57d760b7991d 1312 PRINTS PR00379 Intein signature 630 642 4.5E-25 T 23-10-2018 IPR006142 Intein GO:0016539 VMUT_0644 f99220fd7b77925e720d57d760b7991d 1312 PRINTS PR00379 Intein signature 736 748 4.5E-25 T 23-10-2018 IPR006142 Intein GO:0016539 VMUT_0644 f99220fd7b77925e720d57d760b7991d 1312 PRINTS PR00379 Intein signature 881 890 4.5E-25 T 23-10-2018 IPR006142 Intein GO:0016539 VMUT_0644 f99220fd7b77925e720d57d760b7991d 1312 PRINTS PR00379 Intein signature 763 778 4.5E-25 T 23-10-2018 IPR006142 Intein GO:0016539 VMUT_0644 f99220fd7b77925e720d57d760b7991d 1312 PRINTS PR00379 Intein signature 863 880 4.5E-25 T 23-10-2018 IPR006142 Intein GO:0016539 VMUT_0644 f99220fd7b77925e720d57d760b7991d 1312 Pfam PF14890 Intein splicing domain 593 886 4.2E-12 T 23-10-2018 VMUT_0644 f99220fd7b77925e720d57d760b7991d 1312 SUPERFAMILY SSF51998 239 1240 1.3E-137 T 23-10-2018 VMUT_0644 f99220fd7b77925e720d57d760b7991d 1312 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 158 237 4.6E-23 T 23-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 VMUT_0644 f99220fd7b77925e720d57d760b7991d 1312 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 865 887 9.5E-6 T 23-10-2018 IPR030934 Intein C-terminal splicing region VMUT_0644 f99220fd7b77925e720d57d760b7991d 1312 Gene3D G3DSA:3.10.28.10 720 848 5.6E-19 T 23-10-2018 IPR027434 Homing endonuclease VMUT_0644 f99220fd7b77925e720d57d760b7991d 1312 SUPERFAMILY SSF51294 469 886 7.65E-36 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 VMUT_0644 f99220fd7b77925e720d57d760b7991d 1312 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 470 560 4.3E-14 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 VMUT_0644 f99220fd7b77925e720d57d760b7991d 1312 SMART SM00305 847 892 2.2E-8 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 VMUT_0644 f99220fd7b77925e720d57d760b7991d 1312 SMART SM00306 468 611 3.7E-17 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 VMUT_0644 f99220fd7b77925e720d57d760b7991d 1312 SUPERFAMILY SSF48168 19 238 8.76E-40 T 23-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 VMUT_0644 f99220fd7b77925e720d57d760b7991d 1312 Gene3D G3DSA:2.170.16.10 511 656 4.7E-9 T 23-10-2018 VMUT_0644 f99220fd7b77925e720d57d760b7991d 1312 Gene3D G3DSA:3.20.70.20 103 482 1.1E-106 T 23-10-2018 VMUT_0644 f99220fd7b77925e720d57d760b7991d 1312 Pfam PF14528 LAGLIDADG-like domain 735 831 7.5E-21 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 VMUT_0644 f99220fd7b77925e720d57d760b7991d 1312 Pfam PF02867 Ribonucleotide reductase, barrel domain 240 1227 4.3E-148 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 VMUT_1846 77d6ebccad74fe3bf49f0d53f59d2047 233 Pfam PF04010 Protein of unknown function (DUF357) 13 75 3.2E-17 T 23-10-2018 IPR023140 Domain of unknown function DUF357 VMUT_1846 77d6ebccad74fe3bf49f0d53f59d2047 233 Pfam PF01467 Cytidylyltransferase-like 96 224 6.9E-9 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 VMUT_1846 77d6ebccad74fe3bf49f0d53f59d2047 233 SUPERFAMILY SSF158372 7 78 4.84E-17 T 23-10-2018 IPR036809 AF1782-like superfamily VMUT_1846 77d6ebccad74fe3bf49f0d53f59d2047 233 SUPERFAMILY SSF52374 92 225 7.32E-14 T 23-10-2018 VMUT_1846 77d6ebccad74fe3bf49f0d53f59d2047 233 Gene3D G3DSA:1.20.1270.90 2 77 5.6E-19 T 23-10-2018 VMUT_1846 77d6ebccad74fe3bf49f0d53f59d2047 233 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 94 155 1.7E-9 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 VMUT_1846 77d6ebccad74fe3bf49f0d53f59d2047 233 Gene3D G3DSA:3.40.50.620 91 212 2.8E-23 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_1812 56f4ab4d95e77a3aa899a23e3fa9730f 799 Pfam PF13718 GNAT acetyltransferase 2 468 583 1.0E-28 T 23-10-2018 IPR000182 GNAT domain VMUT_1812 56f4ab4d95e77a3aa899a23e3fa9730f 799 Gene3D G3DSA:3.40.50.12320 244 418 4.4E-35 T 23-10-2018 VMUT_1812 56f4ab4d95e77a3aa899a23e3fa9730f 799 Pfam PF08351 Domain of unknown function (DUF1726) 87 180 9.6E-27 T 23-10-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 VMUT_1812 56f4ab4d95e77a3aa899a23e3fa9730f 799 SUPERFAMILY SSF55729 463 633 2.74E-14 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase VMUT_1812 56f4ab4d95e77a3aa899a23e3fa9730f 799 Pfam PF05127 Helicase 247 428 1.8E-57 T 23-10-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 VMUT_1812 56f4ab4d95e77a3aa899a23e3fa9730f 799 Gene3D G3DSA:3.40.630.30 429 632 3.0E-55 T 23-10-2018 VMUT_1812 56f4ab4d95e77a3aa899a23e3fa9730f 799 SUPERFAMILY SSF52540 216 369 2.41E-6 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1812 56f4ab4d95e77a3aa899a23e3fa9730f 799 Gene3D G3DSA:3.40.50.11040 4 224 7.6E-11 T 23-10-2018 VMUT_1812 56f4ab4d95e77a3aa899a23e3fa9730f 799 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 18 778 44.094 T 23-10-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 VMUT_1942 8a0604bc39e29537fea1411c49ae8df7 223 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 2 217 39.544 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 VMUT_1942 8a0604bc39e29537fea1411c49ae8df7 223 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 3 217 3.6E-79 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 VMUT_1942 8a0604bc39e29537fea1411c49ae8df7 223 SUPERFAMILY SSF52317 2 202 6.45E-64 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like VMUT_1942 8a0604bc39e29537fea1411c49ae8df7 223 Gene3D G3DSA:3.40.50.880 1 211 1.0E-62 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like VMUT_1942 8a0604bc39e29537fea1411c49ae8df7 223 SMART SM01211 1 219 1.7E-101 T 23-10-2018 VMUT_1942 8a0604bc39e29537fea1411c49ae8df7 223 PIRSF PIRSF001586 1 221 2.3E-71 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 VMUT_1942 8a0604bc39e29537fea1411c49ae8df7 223 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 201 5.0E-36 T 23-10-2018 VMUT_1681 02f4505370ec21fb84b9e05463c7d1ae 155 SUPERFAMILY SSF55729 1 145 7.25E-28 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase VMUT_1681 02f4505370ec21fb84b9e05463c7d1ae 155 Gene3D G3DSA:3.40.630.30 1 151 7.6E-31 T 23-10-2018 VMUT_1681 02f4505370ec21fb84b9e05463c7d1ae 155 Pfam PF00583 Acetyltransferase (GNAT) family 28 144 1.0E-18 T 23-10-2018 IPR000182 GNAT domain VMUT_0080 5ee8f7978ba5e590e92b5cf2211de919 262 Pfam PF02511 Thymidylate synthase complementing protein 18 202 1.8E-39 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 VMUT_0080 5ee8f7978ba5e590e92b5cf2211de919 262 Gene3D G3DSA:3.30.1360.170 1 212 4.5E-40 T 23-10-2018 VMUT_0080 5ee8f7978ba5e590e92b5cf2211de919 262 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 31 207 9.6E-28 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 VMUT_0080 5ee8f7978ba5e590e92b5cf2211de919 262 SUPERFAMILY SSF69796 12 211 1.11E-39 T 23-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 VMUT_1312 a7bd71f2602c23b668eb87237a590b78 380 SUPERFAMILY SSF102114 17 354 1.44E-50 T 23-10-2018 VMUT_1312 a7bd71f2602c23b668eb87237a590b78 380 TIGRFAM TIGR04053 sam_11: radical SAM protein, BA_1875 family 13 377 4.6E-141 T 23-10-2018 IPR027634 Radical SAM protein, BA_1875 family VMUT_1312 a7bd71f2602c23b668eb87237a590b78 380 Pfam PF13353 4Fe-4S single cluster domain 26 131 4.8E-7 T 23-10-2018 VMUT_1312 a7bd71f2602c23b668eb87237a590b78 380 Pfam PF04055 Radical SAM superfamily 24 174 8.0E-16 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_1312 a7bd71f2602c23b668eb87237a590b78 380 SMART SM00729 19 227 4.8E-5 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VMUT_1312 a7bd71f2602c23b668eb87237a590b78 380 PIRSF PIRSF037420 6 380 6.3E-70 T 23-10-2018 IPR017200 Coenzyme PQQ synthesis protein E VMUT_1312 a7bd71f2602c23b668eb87237a590b78 380 Gene3D G3DSA:3.20.20.70 16 337 4.1E-36 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_1429 7cf62aa35c9adef9239ba59009c8e0b4 267 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 114 186 4.7E-8 T 23-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase VMUT_1429 7cf62aa35c9adef9239ba59009c8e0b4 267 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 3 257 9.1E-63 T 23-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 VMUT_1429 7cf62aa35c9adef9239ba59009c8e0b4 267 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 6 87 1.6E-24 T 23-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 VMUT_1429 7cf62aa35c9adef9239ba59009c8e0b4 267 SUPERFAMILY SSF51735 101 252 4.26E-25 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1429 7cf62aa35c9adef9239ba59009c8e0b4 267 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 1 267 28.564 T 23-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 VMUT_1429 7cf62aa35c9adef9239ba59009c8e0b4 267 Gene3D G3DSA:3.40.50.720 99 232 3.4E-67 T 23-10-2018 VMUT_1429 7cf62aa35c9adef9239ba59009c8e0b4 267 Gene3D G3DSA:3.40.50.10860 4 250 3.4E-67 T 23-10-2018 VMUT_1429 7cf62aa35c9adef9239ba59009c8e0b4 267 SUPERFAMILY SSF53223 2 99 2.48E-28 T 23-10-2018 VMUT_0146 4415997b817e9dcd7acf5fc337af975f 327 Pfam PF01967 MoaC family 184 320 4.6E-32 T 23-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VMUT_0146 4415997b817e9dcd7acf5fc337af975f 327 Pfam PF01967 MoaC family 5 126 1.1E-23 T 23-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VMUT_0146 4415997b817e9dcd7acf5fc337af975f 327 Gene3D G3DSA:3.30.70.640 181 327 5.2E-41 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VMUT_0146 4415997b817e9dcd7acf5fc337af975f 327 SUPERFAMILY SSF55040 3 126 1.31E-25 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VMUT_0146 4415997b817e9dcd7acf5fc337af975f 327 SUPERFAMILY SSF55040 182 304 3.01E-32 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VMUT_0146 4415997b817e9dcd7acf5fc337af975f 327 Gene3D G3DSA:3.30.70.640 1 145 1.8E-28 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VMUT_1648 691819bb6449c27d4e454402f87e67db 235 SUPERFAMILY SSF56784 1 232 1.97E-40 T 23-10-2018 IPR036412 HAD-like superfamily VMUT_1648 691819bb6449c27d4e454402f87e67db 235 Hamap MF_01419 Phosphoglycolate phosphatase. 2 233 24.916 T 23-10-2018 IPR006382 Phosphoglycolate phosphatase GO:0000287|GO:0008967|GO:0016311 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 VMUT_1648 691819bb6449c27d4e454402f87e67db 235 TIGRFAM TIGR01487 Pglycolate_arch: phosphoglycolate phosphatase, TA0175-type 2 228 1.1E-43 T 23-10-2018 VMUT_1648 691819bb6449c27d4e454402f87e67db 235 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 201 1.8E-18 T 23-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 VMUT_1648 691819bb6449c27d4e454402f87e67db 235 Gene3D G3DSA:3.40.50.1000 5 221 6.4E-53 T 23-10-2018 IPR023214 HAD superfamily VMUT_1648 691819bb6449c27d4e454402f87e67db 235 Pfam PF08282 haloacid dehalogenase-like hydrolase 131 228 5.5E-17 T 23-10-2018 VMUT_1648 691819bb6449c27d4e454402f87e67db 235 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 80 8.9E-6 T 23-10-2018 VMUT_1648 691819bb6449c27d4e454402f87e67db 235 Gene3D G3DSA:3.90.1070.10 83 154 6.4E-53 T 23-10-2018 VMUT_1128 47ad267e4dbb4aefd72e4f8fe56a92f8 77 SMART SM01389 17 77 4.6E-29 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 VMUT_1128 47ad267e4dbb4aefd72e4f8fe56a92f8 77 Hamap MF_00949 Transcription elongation factor Spt4 [spt4]. 19 77 29.776 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 VMUT_1128 47ad267e4dbb4aefd72e4f8fe56a92f8 77 ProDom PD019197 RNA DNA-DIRECTED POLYMERASE SUBUNIT E'' POLYMERASE RPOE2 TRANSFERASE NUCLEOTIDYLTRANSFERASE E 27 76 1.0E-8 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 VMUT_1128 47ad267e4dbb4aefd72e4f8fe56a92f8 77 Pfam PF06093 Spt4/RpoE2 zinc finger 18 76 3.8E-16 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 VMUT_1128 47ad267e4dbb4aefd72e4f8fe56a92f8 77 Gene3D G3DSA:2.20.28.90 12 77 3.9E-25 T 23-10-2018 IPR038589 Archaeal transcription elongation factor Spt4 superfamily VMUT_1128 47ad267e4dbb4aefd72e4f8fe56a92f8 77 SUPERFAMILY SSF63393 13 76 8.37E-22 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 VMUT_0627 8a19fa12d95274c3f5ef5b1329796b76 446 Pfam PF02978 Signal peptide binding domain 326 430 1.0E-24 T 23-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 VMUT_0627 8a19fa12d95274c3f5ef5b1329796b76 446 SUPERFAMILY SSF47364 6 92 9.42E-17 T 23-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 VMUT_0627 8a19fa12d95274c3f5ef5b1329796b76 446 SMART SM00962 101 296 4.3E-81 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 VMUT_0627 8a19fa12d95274c3f5ef5b1329796b76 446 Gene3D G3DSA:1.20.120.140 8 306 3.9E-99 T 23-10-2018 VMUT_0627 8a19fa12d95274c3f5ef5b1329796b76 446 Gene3D G3DSA:3.40.50.300 91 285 3.9E-99 T 23-10-2018 VMUT_0627 8a19fa12d95274c3f5ef5b1329796b76 446 SMART SM00963 9 87 4.1E-11 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 VMUT_0627 8a19fa12d95274c3f5ef5b1329796b76 446 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 3.1E-12 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 VMUT_0627 8a19fa12d95274c3f5ef5b1329796b76 446 SMART SM00382 100 301 1.9E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0627 8a19fa12d95274c3f5ef5b1329796b76 446 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 444 32.174 T 23-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 VMUT_0627 8a19fa12d95274c3f5ef5b1329796b76 446 SUPERFAMILY SSF52540 98 298 1.47E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0627 8a19fa12d95274c3f5ef5b1329796b76 446 Pfam PF00448 SRP54-type protein, GTPase domain 103 296 4.4E-63 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 VMUT_0627 8a19fa12d95274c3f5ef5b1329796b76 446 Gene3D G3DSA:1.10.260.30 307 443 5.0E-33 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 VMUT_0627 8a19fa12d95274c3f5ef5b1329796b76 446 SUPERFAMILY SSF47446 298 433 2.09E-31 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 VMUT_2213 052fb0c278f9cba579ec96c7c5c37916 310 Gene3D G3DSA:3.20.20.70 17 238 3.3E-26 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_2213 052fb0c278f9cba579ec96c7c5c37916 310 SUPERFAMILY SSF102114 20 233 4.84E-30 T 23-10-2018 VMUT_2213 052fb0c278f9cba579ec96c7c5c37916 310 Pfam PF04055 Radical SAM superfamily 22 183 2.2E-21 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_2213 052fb0c278f9cba579ec96c7c5c37916 310 SMART SM00729 16 227 2.4E-4 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VMUT_0391 89e3bee5e0a3aee0a2752d65ae596a92 197 Gene3D G3DSA:3.30.1370.10 84 190 3.9E-35 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 VMUT_0391 89e3bee5e0a3aee0a2752d65ae596a92 197 Gene3D G3DSA:3.30.1370.10 11 82 2.4E-10 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 VMUT_0391 89e3bee5e0a3aee0a2752d65ae596a92 197 SUPERFAMILY SSF54791 26 78 2.92E-5 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 VMUT_0391 89e3bee5e0a3aee0a2752d65ae596a92 197 SUPERFAMILY SSF54791 86 170 1.39E-17 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 VMUT_0391 89e3bee5e0a3aee0a2752d65ae596a92 197 TIGRFAM TIGR03665 arCOG04150: arCOG04150 universal archaeal KH domain protein 13 181 2.5E-51 T 23-10-2018 IPR019964 KH domain protein, archaea VMUT_1863 d291c237742afef1f5aa26a2a6bf68bf 172 SUPERFAMILY SSF55486 54 164 7.84E-15 T 23-10-2018 VMUT_1863 d291c237742afef1f5aa26a2a6bf68bf 172 Pfam PF07998 Peptidase family M54 42 168 1.4E-27 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 VMUT_1863 d291c237742afef1f5aa26a2a6bf68bf 172 Gene3D G3DSA:3.40.390.10 3 172 1.6E-46 T 23-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 VMUT_1863 d291c237742afef1f5aa26a2a6bf68bf 172 PIRSF PIRSF005785 1 172 1.5E-43 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 VMUT_0777 917a227a972314944968c1b5ab526e6c 362 SUPERFAMILY SSF53686 4 359 2.62E-81 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme VMUT_0777 917a227a972314944968c1b5ab526e6c 362 Gene3D G3DSA:3.40.50.1100 92 186 4.1E-95 T 23-10-2018 VMUT_0777 917a227a972314944968c1b5ab526e6c 362 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 61 350 1.8E-65 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme VMUT_0777 917a227a972314944968c1b5ab526e6c 362 Gene3D G3DSA:3.40.50.1100 49 355 4.1E-95 T 23-10-2018 VMUT_0472 907e11c07650232df3138a6b73c947a2 776 Gene3D G3DSA:3.40.50.12610 498 603 4.7E-23 T 23-10-2018 VMUT_0472 907e11c07650232df3138a6b73c947a2 776 Pfam PF02516 Oligosaccharyl transferase STT3 subunit 42 546 9.0E-17 T 23-10-2018 IPR003674 Oligosaccharyl transferase, STT3 subunit GO:0004576|GO:0006486|GO:0016020 VMUT_0926 533153d96a760e1f1063e58882c5cd3e 432 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 39 298 2.0E-74 T 23-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 VMUT_0926 533153d96a760e1f1063e58882c5cd3e 432 Gene3D G3DSA:3.40.50.300 39 245 3.7E-68 T 23-10-2018 VMUT_0926 533153d96a760e1f1063e58882c5cd3e 432 Pfam PF03308 ArgK protein 40 276 5.3E-71 T 23-10-2018 VMUT_0926 533153d96a760e1f1063e58882c5cd3e 432 Gene3D G3DSA:3.10.180.10 302 430 9.1E-36 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VMUT_0926 533153d96a760e1f1063e58882c5cd3e 432 SMART SM00382 40 251 2.2E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0926 533153d96a760e1f1063e58882c5cd3e 432 SUPERFAMILY SSF52540 9 271 7.42E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0926 533153d96a760e1f1063e58882c5cd3e 432 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 307 409 1.3E-20 T 23-10-2018 VMUT_0926 533153d96a760e1f1063e58882c5cd3e 432 SUPERFAMILY SSF54593 303 431 5.91E-31 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VMUT_0926 533153d96a760e1f1063e58882c5cd3e 432 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 305 429 1.2E-38 T 23-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 VMUT_0707 e1f69b04c70fcc2257a9a79335c5c927 238 SUPERFAMILY SSF51556 5 237 3.93E-50 T 23-10-2018 IPR032466 Metal-dependent hydrolase VMUT_0707 e1f69b04c70fcc2257a9a79335c5c927 238 Pfam PF01026 TatD related DNase 5 236 2.3E-45 T 23-10-2018 IPR001130 TatD family GO:0016788 VMUT_0707 e1f69b04c70fcc2257a9a79335c5c927 238 Gene3D G3DSA:3.20.20.140 2 237 4.7E-62 T 23-10-2018 VMUT_0707 e1f69b04c70fcc2257a9a79335c5c927 238 PIRSF PIRSF005902 1 238 6.0E-50 T 23-10-2018 IPR001130 TatD family GO:0016788 VMUT_0303 8e7ee184547fa80ea142a459b1dfe5d3 76 SUPERFAMILY SSF116820 1 61 1.83E-20 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0303 8e7ee184547fa80ea142a459b1dfe5d3 76 Gene3D G3DSA:1.10.60.20 1 62 9.7E-26 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0303 8e7ee184547fa80ea142a459b1dfe5d3 76 Pfam PF00833 Ribosomal S17 1 75 1.4E-18 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0303 8e7ee184547fa80ea142a459b1dfe5d3 76 Hamap MF_00511 30S ribosomal protein S17e [rps17e]. 1 63 20.312 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1347 14f5fef35cd5ec83cba0844d5b4af52b 464 ProSitePatterns PS00216 Sugar transport proteins signature 1. 308 324 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VMUT_1347 14f5fef35cd5ec83cba0844d5b4af52b 464 ProSitePatterns PS00217 Sugar transport proteins signature 2. 118 143 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VMUT_1347 14f5fef35cd5ec83cba0844d5b4af52b 464 Gene3D G3DSA:1.20.1250.20 18 459 3.0E-93 T 23-10-2018 VMUT_1347 14f5fef35cd5ec83cba0844d5b4af52b 464 Pfam PF00083 Sugar (and other) transporter 32 455 3.8E-48 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VMUT_1347 14f5fef35cd5ec83cba0844d5b4af52b 464 SUPERFAMILY SSF103473 2 454 1.01E-65 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_0256 35acd52f7117c1a42f08656d32a50da0 368 Pfam PF04123 Domain of unknown function (DUF373) 7 337 3.6E-84 T 23-10-2018 IPR007254 Protein of unknown function DUF373 VMUT_0215 dc4156482a2a657502041b3f4bbf450d 396 Pfam PF00108 Thiolase, N-terminal domain 5 264 5.0E-77 T 23-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 VMUT_0215 dc4156482a2a657502041b3f4bbf450d 396 ProSitePatterns PS00099 Thiolases active site. 377 390 - T 23-10-2018 IPR020610 Thiolase, active site GO:0016747 VMUT_0215 dc4156482a2a657502041b3f4bbf450d 396 Gene3D G3DSA:3.40.47.10 6 279 1.1E-137 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_0215 dc4156482a2a657502041b3f4bbf450d 396 Pfam PF02803 Thiolase, C-terminal domain 273 394 6.6E-42 T 23-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 VMUT_0215 dc4156482a2a657502041b3f4bbf450d 396 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 23-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 VMUT_0215 dc4156482a2a657502041b3f4bbf450d 396 ProSitePatterns PS00737 Thiolases signature 2. 342 358 - T 23-10-2018 IPR020613 Thiolase, conserved site GO:0016747 VMUT_0215 dc4156482a2a657502041b3f4bbf450d 396 Gene3D G3DSA:3.40.47.10 127 393 1.1E-137 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_0215 dc4156482a2a657502041b3f4bbf450d 396 SUPERFAMILY SSF53901 274 395 1.92E-38 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_0215 dc4156482a2a657502041b3f4bbf450d 396 SUPERFAMILY SSF53901 4 273 2.18E-75 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_0215 dc4156482a2a657502041b3f4bbf450d 396 PIRSF PIRSF000429 1 396 1.8E-124 T 23-10-2018 IPR002155 Thiolase GO:0016747 VMUT_0215 dc4156482a2a657502041b3f4bbf450d 396 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 394 3.0E-129 T 23-10-2018 IPR002155 Thiolase GO:0016747 VMUT_2342 14d6baba65462c7824790abdae6373d8 448 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 114 125 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_2342 14d6baba65462c7824790abdae6373d8 448 Gene3D G3DSA:3.50.50.60 360 408 2.8E-11 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_2342 14d6baba65462c7824790abdae6373d8 448 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 422 5.8E-24 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VMUT_2342 14d6baba65462c7824790abdae6373d8 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 384 406 3.3E-9 T 23-10-2018 VMUT_2342 14d6baba65462c7824790abdae6373d8 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 3.3E-9 T 23-10-2018 VMUT_2342 14d6baba65462c7824790abdae6373d8 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 351 367 3.3E-9 T 23-10-2018 VMUT_2342 14d6baba65462c7824790abdae6373d8 448 Pfam PF12838 4Fe-4S dicluster domain 114 175 4.2E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_2342 14d6baba65462c7824790abdae6373d8 448 Gene3D G3DSA:3.50.50.60 1 98 3.4E-13 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_2342 14d6baba65462c7824790abdae6373d8 448 SUPERFAMILY SSF51905 8 428 4.0E-39 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_2342 14d6baba65462c7824790abdae6373d8 448 Gene3D G3DSA:3.30.70.20 99 131 3.1E-5 T 23-10-2018 VMUT_2342 14d6baba65462c7824790abdae6373d8 448 Gene3D G3DSA:3.30.70.20 138 193 4.2E-8 T 23-10-2018 VMUT_2342 14d6baba65462c7824790abdae6373d8 448 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 161 172 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_2342 14d6baba65462c7824790abdae6373d8 448 Gene3D G3DSA:3.50.50.60 298 359 2.8E-11 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0241 e850a103dab2cb5934ea30dec9b50f03 379 SUPERFAMILY SSF51905 5 373 9.06E-46 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0241 e850a103dab2cb5934ea30dec9b50f03 379 Gene3D G3DSA:3.30.9.10 84 310 5.2E-72 T 23-10-2018 VMUT_0241 e850a103dab2cb5934ea30dec9b50f03 379 Pfam PF01266 FAD dependent oxidoreductase 6 345 1.3E-48 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VMUT_0241 e850a103dab2cb5934ea30dec9b50f03 379 Gene3D G3DSA:3.50.50.60 6 350 5.2E-72 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_2050 c06cff92be7ccef0c6331131fc9c0a0f 414 Hamap MF_01402_A 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 2 405 41.764 T 23-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VMUT_2050 c06cff92be7ccef0c6331131fc9c0a0f 414 Pfam PF01676 Metalloenzyme superfamily 3 402 1.0E-40 T 23-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 VMUT_2050 c06cff92be7ccef0c6331131fc9c0a0f 414 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 39 213 1.9E-47 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VMUT_2050 c06cff92be7ccef0c6331131fc9c0a0f 414 PIRSF PIRSF006392 1 410 1.5E-137 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VMUT_2050 c06cff92be7ccef0c6331131fc9c0a0f 414 SUPERFAMILY SSF53649 1 407 7.85E-36 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 VMUT_2050 c06cff92be7ccef0c6331131fc9c0a0f 414 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 5 402 3.0E-129 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VMUT_2050 c06cff92be7ccef0c6331131fc9c0a0f 414 Gene3D G3DSA:3.40.720.10 5 400 9.4E-123 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 VMUT_2050 c06cff92be7ccef0c6331131fc9c0a0f 414 Gene3D G3DSA:3.30.70.2130 79 235 9.4E-123 T 23-10-2018 VMUT_1899 0ecf5dd47dee40ac149e3cfc9744c54c 307 Gene3D G3DSA:3.40.50.970 21 196 6.6E-26 T 23-10-2018 VMUT_1899 0ecf5dd47dee40ac149e3cfc9744c54c 307 SUPERFAMILY SSF52518 7 272 1.08E-76 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold VMUT_1899 0ecf5dd47dee40ac149e3cfc9744c54c 307 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 196 269 9.3E-24 T 23-10-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal VMUT_1899 0ecf5dd47dee40ac149e3cfc9744c54c 307 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 45 192 2.1E-31 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 VMUT_1899 0ecf5dd47dee40ac149e3cfc9744c54c 307 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 11 302 1.0E-133 T 23-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate VMUT_1580 71a003e53955de96d5085af9421e384f 225 Hamap MF_00291_A 30S ribosomal protein S2 [rpsB]. 18 218 46.696 T 23-10-2018 IPR023454 Ribosomal protein S2, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_1580 71a003e53955de96d5085af9421e384f 225 SUPERFAMILY SSF52313 23 210 1.11E-55 T 23-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily VMUT_1580 71a003e53955de96d5085af9421e384f 225 TIGRFAM TIGR01012 uS2_euk_arch: ribosomal protein uS2 23 217 1.2E-79 T 23-10-2018 IPR005707 Ribosomal protein S2, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1580 71a003e53955de96d5085af9421e384f 225 Pfam PF00318 Ribosomal protein S2 132 194 2.4E-14 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_1580 71a003e53955de96d5085af9421e384f 225 PRINTS PR00395 Ribosomal protein S2 signature 106 123 7.0E-23 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_1580 71a003e53955de96d5085af9421e384f 225 PRINTS PR00395 Ribosomal protein S2 signature 148 159 7.0E-23 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_1580 71a003e53955de96d5085af9421e384f 225 PRINTS PR00395 Ribosomal protein S2 signature 131 148 7.0E-23 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_1580 71a003e53955de96d5085af9421e384f 225 PRINTS PR00395 Ribosomal protein S2 signature 169 183 7.0E-23 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_1580 71a003e53955de96d5085af9421e384f 225 PRINTS PR00395 Ribosomal protein S2 signature 26 44 7.0E-23 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_1580 71a003e53955de96d5085af9421e384f 225 PRINTS PR00395 Ribosomal protein S2 signature 58 67 7.0E-23 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_1580 71a003e53955de96d5085af9421e384f 225 Gene3D G3DSA:3.40.50.10490 25 221 1.7E-62 T 23-10-2018 VMUT_0948 3423e2b765df5409ed21c6023f44ce6a 391 SUPERFAMILY SSF52540 43 201 6.56E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0948 3423e2b765df5409ed21c6023f44ce6a 391 Pfam PF07728 AAA domain (dynein-related subfamily) 53 179 2.4E-26 T 23-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 VMUT_0948 3423e2b765df5409ed21c6023f44ce6a 391 SMART SM00382 49 189 1.0E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0948 3423e2b765df5409ed21c6023f44ce6a 391 Gene3D G3DSA:3.40.50.300 13 216 2.7E-38 T 23-10-2018 VMUT_0948 3423e2b765df5409ed21c6023f44ce6a 391 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 121 139 5.3E-5 T 23-10-2018 IPR001270 ClpA/B family GO:0005524 VMUT_0948 3423e2b765df5409ed21c6023f44ce6a 391 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 53 71 5.3E-5 T 23-10-2018 IPR001270 ClpA/B family GO:0005524 VMUT_1628 a6ede971fa1c15c02ffdf4443effccbf 99 SUPERFAMILY SSF103473 9 96 3.4E-12 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_1628 a6ede971fa1c15c02ffdf4443effccbf 99 Gene3D G3DSA:1.20.1250.20 1 99 1.2E-14 T 23-10-2018 VMUT_1628 a6ede971fa1c15c02ffdf4443effccbf 99 ProSitePatterns PS00217 Sugar transport proteins signature 2. 68 93 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VMUT_1628 a6ede971fa1c15c02ffdf4443effccbf 99 Pfam PF00083 Sugar (and other) transporter 8 93 3.9E-10 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VMUT_0045 159e3f519e40e65c55fdab6ca2c377ff 110 Pfam PF01909 Nucleotidyltransferase domain 20 93 5.2E-9 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 VMUT_0045 159e3f519e40e65c55fdab6ca2c377ff 110 SUPERFAMILY SSF81301 11 100 9.54E-12 T 23-10-2018 VMUT_0045 159e3f519e40e65c55fdab6ca2c377ff 110 Gene3D G3DSA:3.30.460.10 15 110 6.1E-19 T 23-10-2018 VMUT_0458 1e0d1a57e43e010968463b0ae48035a2 885 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 40 288 5.9E-8 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain VMUT_0458 1e0d1a57e43e010968463b0ae48035a2 885 Gene3D G3DSA:3.10.105.10 94 347 1.0E-10 T 23-10-2018 VMUT_0458 1e0d1a57e43e010968463b0ae48035a2 885 SUPERFAMILY SSF53850 40 377 1.47E-17 T 23-10-2018 VMUT_1431 c5138d4293b5f57181a073d87f316207 331 Gene3D G3DSA:3.20.20.70 55 321 4.4E-98 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_1431 c5138d4293b5f57181a073d87f316207 331 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 66 319 4.5E-124 T 23-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 VMUT_1431 c5138d4293b5f57181a073d87f316207 331 SUPERFAMILY SSF51569 50 329 2.66E-95 T 23-10-2018 VMUT_1431 c5138d4293b5f57181a073d87f316207 331 Pfam PF00793 DAHP synthetase I family 80 324 5.2E-74 T 23-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 VMUT_1432 ada73d2ebea3b329343ff521bcbbae98 336 SUPERFAMILY SSF48600 9 93 8.85E-19 T 23-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 VMUT_1432 ada73d2ebea3b329343ff521bcbbae98 336 SUPERFAMILY SSF51735 93 235 9.38E-14 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1432 ada73d2ebea3b329343ff521bcbbae98 336 Pfam PF02153 Prephenate dehydrogenase 130 305 2.5E-17 T 23-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 VMUT_1432 ada73d2ebea3b329343ff521bcbbae98 336 SMART SM00830 15 95 4.5E-18 T 23-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 VMUT_1432 ada73d2ebea3b329343ff521bcbbae98 336 Gene3D G3DSA:1.20.59.10 7 83 4.5E-17 T 23-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 VMUT_1432 ada73d2ebea3b329343ff521bcbbae98 336 Pfam PF01817 Chorismate mutase type II 15 92 3.3E-16 T 23-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 VMUT_1432 ada73d2ebea3b329343ff521bcbbae98 336 Gene3D G3DSA:3.40.50.720 84 243 2.4E-20 T 23-10-2018 VMUT_1432 ada73d2ebea3b329343ff521bcbbae98 336 SUPERFAMILY SSF48179 238 327 5.44E-9 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VMUT_1371 a8e61635bb1d27553c38f7f02d1b46b6 348 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 138 7.1E-30 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VMUT_1371 a8e61635bb1d27553c38f7f02d1b46b6 348 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 23-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 VMUT_1371 a8e61635bb1d27553c38f7f02d1b46b6 348 SMART SM00829 8 345 4.1E-7 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VMUT_1371 a8e61635bb1d27553c38f7f02d1b46b6 348 Gene3D G3DSA:3.40.50.720 159 293 2.0E-37 T 23-10-2018 VMUT_1371 a8e61635bb1d27553c38f7f02d1b46b6 348 SUPERFAMILY SSF50129 1 177 4.57E-52 T 23-10-2018 IPR011032 GroES-like superfamily VMUT_1371 a8e61635bb1d27553c38f7f02d1b46b6 348 Pfam PF00107 Zinc-binding dehydrogenase 180 309 3.8E-28 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 VMUT_1371 a8e61635bb1d27553c38f7f02d1b46b6 348 SUPERFAMILY SSF51735 142 314 5.26E-43 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0225 b45bb376f06453b37a0eda87d268eb8c 272 Gene3D G3DSA:3.40.50.300 14 264 6.0E-70 T 23-10-2018 VMUT_0225 b45bb376f06453b37a0eda87d268eb8c 272 Pfam PF03029 Conserved hypothetical ATP binding protein 22 259 1.5E-59 T 23-10-2018 IPR004130 GPN-loop GTPase VMUT_0225 b45bb376f06453b37a0eda87d268eb8c 272 SMART SM00382 16 181 1.6E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0225 b45bb376f06453b37a0eda87d268eb8c 272 SUPERFAMILY SSF52540 18 260 9.43E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0518 499de907cb78a93aa2d2c91ff8d635b4 419 PIRSF PIRSF000530 1 409 5.4E-61 T 23-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 VMUT_0518 499de907cb78a93aa2d2c91ff8d635b4 419 Pfam PF00288 GHMP kinases N terminal domain 117 182 3.2E-12 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 VMUT_0518 499de907cb78a93aa2d2c91ff8d635b4 419 Gene3D G3DSA:3.30.70.890 279 410 4.2E-23 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily VMUT_0518 499de907cb78a93aa2d2c91ff8d635b4 419 SUPERFAMILY SSF55060 204 411 1.06E-23 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily VMUT_0518 499de907cb78a93aa2d2c91ff8d635b4 419 Pfam PF10509 Galactokinase galactose-binding signature 9 57 1.7E-11 T 23-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 VMUT_0518 499de907cb78a93aa2d2c91ff8d635b4 419 SUPERFAMILY SSF54211 6 198 1.21E-40 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VMUT_0518 499de907cb78a93aa2d2c91ff8d635b4 419 PRINTS PR00959 Mevalonate kinase family signature 163 182 1.9E-26 T 23-10-2018 VMUT_0518 499de907cb78a93aa2d2c91ff8d635b4 419 PRINTS PR00959 Mevalonate kinase family signature 24 48 1.9E-26 T 23-10-2018 VMUT_0518 499de907cb78a93aa2d2c91ff8d635b4 419 PRINTS PR00959 Mevalonate kinase family signature 367 384 1.9E-26 T 23-10-2018 VMUT_0518 499de907cb78a93aa2d2c91ff8d635b4 419 PRINTS PR00959 Mevalonate kinase family signature 120 142 1.9E-26 T 23-10-2018 VMUT_0518 499de907cb78a93aa2d2c91ff8d635b4 419 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 122 133 - T 23-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 VMUT_0518 499de907cb78a93aa2d2c91ff8d635b4 419 Pfam PF08544 GHMP kinases C terminal 343 396 1.4E-12 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain VMUT_0518 499de907cb78a93aa2d2c91ff8d635b4 419 Gene3D G3DSA:3.30.230.10 2 207 5.5E-40 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup VMUT_0779 3e3a757b6ca86320589061451d35b441 498 Pfam PF00221 Aromatic amino acid lyase 11 464 1.8E-143 T 23-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 VMUT_0779 3e3a757b6ca86320589061451d35b441 498 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 139 155 - T 23-10-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 VMUT_0779 3e3a757b6ca86320589061451d35b441 498 SUPERFAMILY SSF48557 8 477 1.41E-142 T 23-10-2018 IPR008948 L-Aspartase-like GO:0003824 VMUT_0779 3e3a757b6ca86320589061451d35b441 498 Gene3D G3DSA:1.20.200.10 198 492 2.3E-71 T 23-10-2018 VMUT_0779 3e3a757b6ca86320589061451d35b441 498 Gene3D G3DSA:1.10.275.10 3 197 4.4E-61 T 23-10-2018 IPR024083 Fumarase/histidase, N-terminal VMUT_1851 866dfb91a74b0ea2aec9ac46c26bbe3c 178 SMART SM00359 90 164 3.7E-19 T 23-10-2018 IPR002478 PUA domain GO:0003723 VMUT_1851 866dfb91a74b0ea2aec9ac46c26bbe3c 178 Gene3D G3DSA:2.30.130.10 87 171 1.4E-29 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 VMUT_1851 866dfb91a74b0ea2aec9ac46c26bbe3c 178 SUPERFAMILY SSF88697 89 170 5.36E-25 T 23-10-2018 IPR015947 PUA-like superfamily VMUT_1851 866dfb91a74b0ea2aec9ac46c26bbe3c 178 Pfam PF09183 Domain of unknown function (DUF1947) 8 58 4.1E-7 T 23-10-2018 IPR015266 Domain of unknown function DUF1947 VMUT_1851 866dfb91a74b0ea2aec9ac46c26bbe3c 178 TIGRFAM TIGR03684 arCOG00985: arCOG04150 universal archaeal PUA-domain protein 9 170 1.5E-38 T 23-10-2018 IPR022430 Conserved hypothetical protein CHP03684 VMUT_1851 866dfb91a74b0ea2aec9ac46c26bbe3c 178 Pfam PF01472 PUA domain 90 163 7.3E-21 T 23-10-2018 IPR002478 PUA domain GO:0003723 VMUT_1851 866dfb91a74b0ea2aec9ac46c26bbe3c 178 PIRSF PIRSF005067 2 175 2.4E-32 T 23-10-2018 IPR016437 MCT-1/Tma20 VMUT_1851 866dfb91a74b0ea2aec9ac46c26bbe3c 178 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 85 165 2.9E-21 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 VMUT_0633 d282ba210b4149c6f6445a427f7a49d0 326 SMART SM00893 7 193 1.1E-30 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 VMUT_0633 d282ba210b4149c6f6445a427f7a49d0 326 Gene3D G3DSA:3.40.50.1220 201 326 1.5E-35 T 23-10-2018 VMUT_0633 d282ba210b4149c6f6445a427f7a49d0 326 SUPERFAMILY SSF52402 6 188 4.19E-40 T 23-10-2018 VMUT_0633 d282ba210b4149c6f6445a427f7a49d0 326 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 205 284 1.4E-18 T 23-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 VMUT_0633 d282ba210b4149c6f6445a427f7a49d0 326 SUPERFAMILY SSF52467 203 322 5.45E-33 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily VMUT_0633 d282ba210b4149c6f6445a427f7a49d0 326 Pfam PF01012 Electron transfer flavoprotein domain 8 184 4.6E-31 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 VMUT_0633 d282ba210b4149c6f6445a427f7a49d0 326 Gene3D G3DSA:3.40.50.620 3 200 2.1E-55 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_0633 d282ba210b4149c6f6445a427f7a49d0 326 PIRSF PIRSF000089 3 326 4.4E-77 T 23-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 VMUT_0860 483ccd07bb928657363f23f82e78322b 358 Gene3D G3DSA:1.10.150.20 51 112 1.6E-16 T 23-10-2018 VMUT_0860 483ccd07bb928657363f23f82e78322b 358 Pfam PF14520 Helix-hairpin-helix domain 51 104 2.8E-8 T 23-10-2018 VMUT_0860 483ccd07bb928657363f23f82e78322b 358 Pfam PF08423 Rad51 111 358 3.4E-96 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 VMUT_0860 483ccd07bb928657363f23f82e78322b 358 PIRSF PIRSF005856 36 358 5.7E-128 T 23-10-2018 IPR016467 DNA recombination and repair protein, RecA-like Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 VMUT_0860 483ccd07bb928657363f23f82e78322b 358 Hamap MF_00348 DNA repair and recombination protein RadA [radA]. 49 358 74.751 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 VMUT_0860 483ccd07bb928657363f23f82e78322b 358 SMART SM00382 144 328 2.8E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0860 483ccd07bb928657363f23f82e78322b 358 SUPERFAMILY SSF52540 124 357 3.87E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0860 483ccd07bb928657363f23f82e78322b 358 Gene3D G3DSA:3.40.50.300 113 358 2.5E-84 T 23-10-2018 VMUT_0860 483ccd07bb928657363f23f82e78322b 358 TIGRFAM TIGR02236 recomb_radA: DNA repair and recombination protein RadA 51 358 1.7E-145 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 VMUT_0860 483ccd07bb928657363f23f82e78322b 358 SUPERFAMILY SSF47794 47 106 3.45E-12 T 23-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 VMUT_1280 6825b344469313c2d41db40beb31a966 460 SUPERFAMILY SSF51395 43 457 8.24E-54 T 23-10-2018 VMUT_1280 6825b344469313c2d41db40beb31a966 460 Pfam PF01645 Conserved region in glutamate synthase 221 399 5.7E-20 T 23-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 VMUT_1280 6825b344469313c2d41db40beb31a966 460 Gene3D G3DSA:3.20.20.70 114 407 1.2E-39 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_1025 5dcdbdc10dd3bf862c3f58e00e85d8eb 132 Gene3D G3DSA:3.30.460.10 5 93 2.4E-5 T 23-10-2018 VMUT_1025 5dcdbdc10dd3bf862c3f58e00e85d8eb 132 SUPERFAMILY SSF81301 9 90 2.7E-7 T 23-10-2018 VMUT_0536 1a206dc0cb98a59fa8e1e2a24b07c33b 567 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 10 567 48.078 T 23-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VMUT_0536 1a206dc0cb98a59fa8e1e2a24b07c33b 567 Pfam PF00920 Dehydratase family 40 564 3.6E-220 T 23-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VMUT_0536 1a206dc0cb98a59fa8e1e2a24b07c33b 567 SUPERFAMILY SSF143975 7 388 3.01E-140 T 23-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VMUT_0536 1a206dc0cb98a59fa8e1e2a24b07c33b 567 SUPERFAMILY SSF52016 389 566 7.85E-61 T 23-10-2018 VMUT_0536 1a206dc0cb98a59fa8e1e2a24b07c33b 567 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 475 486 - T 23-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VMUT_0536 1a206dc0cb98a59fa8e1e2a24b07c33b 567 Gene3D G3DSA:3.50.30.80 389 538 7.3E-55 T 23-10-2018 VMUT_0536 1a206dc0cb98a59fa8e1e2a24b07c33b 567 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 23 566 2.4E-232 T 23-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VMUT_0536 1a206dc0cb98a59fa8e1e2a24b07c33b 567 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 128 138 - T 23-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VMUT_0540 0f2af371d8f943d28149cd07231553b2 372 Gene3D G3DSA:3.40.50.10840 7 221 5.3E-14 T 23-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily VMUT_0540 0f2af371d8f943d28149cd07231553b2 372 Pfam PF07005 Putative sugar-binding N-terminal domain 11 134 5.9E-14 T 23-10-2018 IPR010737 Four-carbon acid sugar kinase, N-terminal domain VMUT_0540 0f2af371d8f943d28149cd07231553b2 372 SUPERFAMILY SSF142764 11 362 1.96E-40 T 23-10-2018 VMUT_0768 543ad5d3c4f07df66abb49273c2f0f9a 317 Hamap MF_01406 UPF0282 protein . 1 296 37.164 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase VMUT_0768 543ad5d3c4f07df66abb49273c2f0f9a 317 SUPERFAMILY SSF56281 16 273 1.09E-10 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_0768 543ad5d3c4f07df66abb49273c2f0f9a 317 Gene3D G3DSA:3.60.15.10 13 202 3.6E-7 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_0768 543ad5d3c4f07df66abb49273c2f0f9a 317 PIRSF PIRSF004944 1 315 1.0E-91 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase VMUT_2113 43d0db69933cc8ff4e9d573d128f6777 1004 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 11 857 9.1E-246 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 VMUT_2113 43d0db69933cc8ff4e9d573d128f6777 1004 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 54 65 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_2113 43d0db69933cc8ff4e9d573d128f6777 1004 SUPERFAMILY SSF50677 207 406 1.99E-53 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 VMUT_2113 43d0db69933cc8ff4e9d573d128f6777 1004 SUPERFAMILY SSF47323 911 992 2.75E-6 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_2113 43d0db69933cc8ff4e9d573d128f6777 1004 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 25 646 7.3E-164 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_2113 43d0db69933cc8ff4e9d573d128f6777 1004 Pfam PF08264 Anticodon-binding domain of tRNA 700 851 1.6E-22 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 VMUT_2113 43d0db69933cc8ff4e9d573d128f6777 1004 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 228 251 1.5E-25 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 VMUT_2113 43d0db69933cc8ff4e9d573d128f6777 1004 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 532 545 1.5E-25 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 VMUT_2113 43d0db69933cc8ff4e9d573d128f6777 1004 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 404 419 1.5E-25 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 VMUT_2113 43d0db69933cc8ff4e9d573d128f6777 1004 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 571 580 1.5E-25 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 VMUT_2113 43d0db69933cc8ff4e9d573d128f6777 1004 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 47 58 1.5E-25 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 VMUT_2113 43d0db69933cc8ff4e9d573d128f6777 1004 Gene3D G3DSA:3.40.50.620 20 638 9.1E-211 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_2113 43d0db69933cc8ff4e9d573d128f6777 1004 SUPERFAMILY SSF52374 13 659 8.57E-118 T 23-10-2018 VMUT_2113 43d0db69933cc8ff4e9d573d128f6777 1004 Gene3D G3DSA:1.10.730.10 657 843 2.2E-35 T 23-10-2018 VMUT_2113 43d0db69933cc8ff4e9d573d128f6777 1004 SUPERFAMILY SSF47323 666 889 9.72E-42 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_2113 43d0db69933cc8ff4e9d573d128f6777 1004 Gene3D G3DSA:3.90.740.10 204 410 9.1E-211 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 VMUT_1102 212b7b6743f70e041b6ba4b73c3a585d 489 Pfam PF01943 Polysaccharide biosynthesis protein 8 264 2.9E-8 T 23-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 VMUT_0336 d5b94e23a8c94086be5fcc4096ab6721 663 SUPERFAMILY SSF52096 401 661 2.26E-87 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VMUT_0336 d5b94e23a8c94086be5fcc4096ab6721 663 Gene3D G3DSA:3.90.226.10 396 603 5.6E-69 T 23-10-2018 VMUT_0336 d5b94e23a8c94086be5fcc4096ab6721 663 Gene3D G3DSA:1.10.1040.10 193 300 1.9E-29 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VMUT_0336 d5b94e23a8c94086be5fcc4096ab6721 663 SUPERFAMILY SSF51735 6 187 4.17E-59 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0336 d5b94e23a8c94086be5fcc4096ab6721 663 SUPERFAMILY SSF48179 190 294 5.7E-28 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VMUT_0336 d5b94e23a8c94086be5fcc4096ab6721 663 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 504 524 - T 23-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 VMUT_0336 d5b94e23a8c94086be5fcc4096ab6721 663 Gene3D G3DSA:1.10.12.10 606 662 7.2E-18 T 23-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal VMUT_0336 d5b94e23a8c94086be5fcc4096ab6721 663 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 309 399 6.5E-22 T 23-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 VMUT_0336 d5b94e23a8c94086be5fcc4096ab6721 663 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 191 285 1.6E-26 T 23-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 VMUT_0336 d5b94e23a8c94086be5fcc4096ab6721 663 Gene3D G3DSA:1.10.1040.10 310 395 2.9E-23 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VMUT_0336 d5b94e23a8c94086be5fcc4096ab6721 663 Pfam PF00378 Enoyl-CoA hydratase/isomerase 420 661 5.4E-64 T 23-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VMUT_0336 d5b94e23a8c94086be5fcc4096ab6721 663 SUPERFAMILY SSF48179 309 399 6.21E-20 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VMUT_0336 d5b94e23a8c94086be5fcc4096ab6721 663 Gene3D G3DSA:3.40.50.720 1 192 3.6E-69 T 23-10-2018 VMUT_0336 d5b94e23a8c94086be5fcc4096ab6721 663 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 9 188 1.3E-66 T 23-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 VMUT_0523 5215a68a815da11e8379a382a92455a4 403 Gene3D G3DSA:3.50.50.60 116 264 8.7E-77 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0523 5215a68a815da11e8379a382a92455a4 403 Gene3D G3DSA:3.50.50.60 14 317 8.7E-77 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0523 5215a68a815da11e8379a382a92455a4 403 SUPERFAMILY SSF51905 11 156 2.31E-22 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0523 5215a68a815da11e8379a382a92455a4 403 SUPERFAMILY SSF51905 129 255 5.51E-26 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0523 5215a68a815da11e8379a382a92455a4 403 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 12 297 2.1E-15 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VMUT_0632 6808beeb0c2d52bd8d48ec496c690b17 264 Pfam PF01012 Electron transfer flavoprotein domain 27 189 1.7E-43 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 VMUT_0632 6808beeb0c2d52bd8d48ec496c690b17 264 Gene3D G3DSA:3.40.50.620 6 263 5.0E-79 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_0632 6808beeb0c2d52bd8d48ec496c690b17 264 PIRSF PIRSF000090 5 263 4.2E-73 T 23-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 VMUT_0632 6808beeb0c2d52bd8d48ec496c690b17 264 SUPERFAMILY SSF52402 6 262 1.74E-63 T 23-10-2018 VMUT_0632 6808beeb0c2d52bd8d48ec496c690b17 264 SMART SM00893 26 218 2.2E-39 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 VMUT_1632 f697d5d441fd45e7553db14b20be3561 616 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 392 528 8.3E-22 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 VMUT_1632 f697d5d441fd45e7553db14b20be3561 616 SUPERFAMILY SSF54862 534 603 2.76E-13 T 23-10-2018 VMUT_1632 f697d5d441fd45e7553db14b20be3561 616 Gene3D G3DSA:3.40.50.970 385 531 7.1E-16 T 23-10-2018 VMUT_1632 f697d5d441fd45e7553db14b20be3561 616 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 585 596 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_1632 f697d5d441fd45e7553db14b20be3561 616 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 17 192 1.3E-13 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 VMUT_1632 f697d5d441fd45e7553db14b20be3561 616 SUPERFAMILY SSF52518 6 227 5.35E-60 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold VMUT_1632 f697d5d441fd45e7553db14b20be3561 616 Gene3D G3DSA:3.40.50.970 1 185 1.8E-56 T 23-10-2018 VMUT_1632 f697d5d441fd45e7553db14b20be3561 616 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 7 600 4.2E-203 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 VMUT_1632 f697d5d441fd45e7553db14b20be3561 616 Gene3D G3DSA:3.40.50.920 231 297 2.1E-5 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VMUT_1632 f697d5d441fd45e7553db14b20be3561 616 SUPERFAMILY SSF52922 229 315 1.73E-11 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VMUT_1632 f697d5d441fd45e7553db14b20be3561 616 SUPERFAMILY SSF52518 343 535 6.51E-26 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold VMUT_1632 f697d5d441fd45e7553db14b20be3561 616 PIRSF PIRSF006439 1 607 4.0E-207 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 VMUT_1632 f697d5d441fd45e7553db14b20be3561 616 Pfam PF00037 4Fe-4S binding domain 579 601 1.1E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_1632 f697d5d441fd45e7553db14b20be3561 616 Gene3D G3DSA:3.30.70.20 548 604 5.4E-9 T 23-10-2018 VMUT_0929 e7afdf3bcd8797e53bf65150e69cd1a4 122 SUPERFAMILY SSF46785 14 118 2.04E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0929 e7afdf3bcd8797e53bf65150e69cd1a4 122 Gene3D G3DSA:1.10.10.10 11 81 9.2E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_0929 e7afdf3bcd8797e53bf65150e69cd1a4 122 Pfam PF03965 Penicillinase repressor 14 70 4.1E-11 T 23-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 VMUT_0682 c5cf870a2e66efd29871656e23554a9c 431 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 13 428 7.3E-194 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 VMUT_0682 c5cf870a2e66efd29871656e23554a9c 431 Gene3D G3DSA:3.40.50.1100 14 236 5.4E-160 T 23-10-2018 VMUT_0682 c5cf870a2e66efd29871656e23554a9c 431 Gene3D G3DSA:3.40.50.1100 13 419 5.4E-160 T 23-10-2018 VMUT_0682 c5cf870a2e66efd29871656e23554a9c 431 PIRSF PIRSF001413 9 431 1.7E-135 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 VMUT_0682 c5cf870a2e66efd29871656e23554a9c 431 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 74 413 8.8E-36 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme VMUT_0682 c5cf870a2e66efd29871656e23554a9c 431 SUPERFAMILY SSF53686 42 425 3.27E-95 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme VMUT_0682 c5cf870a2e66efd29871656e23554a9c 431 PIRSF PIRSF500824 1 431 8.0E-189 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 VMUT_0682 c5cf870a2e66efd29871656e23554a9c 431 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 21 426 39.052 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 VMUT_0587 85bc79c2ff0767ec220cc89b802b171a 231 Pfam PF01209 ubiE/COQ5 methyltransferase family 6 209 8.7E-13 T 23-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 VMUT_0587 85bc79c2ff0767ec220cc89b802b171a 231 Gene3D G3DSA:3.40.50.150 15 230 3.5E-18 T 23-10-2018 VMUT_0587 85bc79c2ff0767ec220cc89b802b171a 231 SUPERFAMILY SSF53335 17 172 2.69E-14 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_0345 c83a94029d065e821da1e2c1f76d4384 303 ProSitePatterns PS01053 Arginase family signature. 226 247 - T 23-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 VMUT_0345 c83a94029d065e821da1e2c1f76d4384 303 PRINTS PR00116 Arginase signature 109 124 1.3E-11 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 VMUT_0345 c83a94029d065e821da1e2c1f76d4384 303 PRINTS PR00116 Arginase signature 223 252 1.3E-11 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 VMUT_0345 c83a94029d065e821da1e2c1f76d4384 303 Pfam PF00491 Arginase family 25 294 2.4E-53 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 VMUT_0345 c83a94029d065e821da1e2c1f76d4384 303 SUPERFAMILY SSF52768 19 300 2.16E-54 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily VMUT_0345 c83a94029d065e821da1e2c1f76d4384 303 PIRSF PIRSF036979 6 303 2.7E-54 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 VMUT_0345 c83a94029d065e821da1e2c1f76d4384 303 Gene3D G3DSA:3.40.800.10 21 302 1.2E-58 T 23-10-2018 VMUT_1977 42f6392edbb2cf2c313de5766cf70f1f 324 SUPERFAMILY SSF51735 101 287 4.29E-37 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1977 42f6392edbb2cf2c313de5766cf70f1f 324 Gene3D G3DSA:3.40.50.720 58 311 4.0E-62 T 23-10-2018 VMUT_1977 42f6392edbb2cf2c313de5766cf70f1f 324 SUPERFAMILY SSF52283 5 116 5.83E-18 T 23-10-2018 VMUT_1977 42f6392edbb2cf2c313de5766cf70f1f 324 Gene3D G3DSA:3.40.50.720 99 287 4.0E-62 T 23-10-2018 VMUT_1977 42f6392edbb2cf2c313de5766cf70f1f 324 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 129 286 1.7E-35 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 VMUT_1977 42f6392edbb2cf2c313de5766cf70f1f 324 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 8 319 5.3E-16 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 VMUT_1780 bf37f9a0afa23c899de9367660b00b3a 443 SMART SM01274 20 153 7.6E-66 T 23-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 VMUT_1780 bf37f9a0afa23c899de9367660b00b3a 443 SUPERFAMILY SSF51735 165 425 6.47E-70 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1780 bf37f9a0afa23c899de9367660b00b3a 443 SMART SM00919 165 397 3.1E-110 T 23-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 VMUT_1780 bf37f9a0afa23c899de9367660b00b3a 443 Pfam PF00390 Malic enzyme, N-terminal domain 23 153 3.7E-21 T 23-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 VMUT_1780 bf37f9a0afa23c899de9367660b00b3a 443 Pfam PF03949 Malic enzyme, NAD binding domain 166 395 5.1E-24 T 23-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 VMUT_1780 bf37f9a0afa23c899de9367660b00b3a 443 Gene3D G3DSA:3.40.50.10380 4 162 5.5E-64 T 23-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 VMUT_1780 bf37f9a0afa23c899de9367660b00b3a 443 PIRSF PIRSF000106 40 428 1.1E-77 T 23-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 VMUT_1780 bf37f9a0afa23c899de9367660b00b3a 443 Gene3D G3DSA:3.40.50.720 163 443 8.2E-89 T 23-10-2018 VMUT_1780 bf37f9a0afa23c899de9367660b00b3a 443 SUPERFAMILY SSF53223 17 163 1.94E-49 T 23-10-2018 VMUT_1969 21661cf39634073020b830e0f54f430f 298 SUPERFAMILY SSF53671 2 294 3.93E-89 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 VMUT_1969 21661cf39634073020b830e0f54f430f 298 Gene3D G3DSA:3.40.50.1370 123 280 6.8E-102 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 VMUT_1969 21661cf39634073020b830e0f54f430f 298 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 142 291 1.9E-25 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 VMUT_1969 21661cf39634073020b830e0f54f430f 298 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 3 293 1.8E-107 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VMUT_1969 21661cf39634073020b830e0f54f430f 298 Gene3D G3DSA:3.40.50.1370 3 290 6.8E-102 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 VMUT_1969 21661cf39634073020b830e0f54f430f 298 PRINTS PR00101 Aspartate carbamoyltransferase signature 29 51 7.2E-32 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VMUT_1969 21661cf39634073020b830e0f54f430f 298 PRINTS PR00101 Aspartate carbamoyltransferase signature 68 77 7.2E-32 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VMUT_1969 21661cf39634073020b830e0f54f430f 298 PRINTS PR00101 Aspartate carbamoyltransferase signature 252 257 7.2E-32 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VMUT_1969 21661cf39634073020b830e0f54f430f 298 PRINTS PR00101 Aspartate carbamoyltransferase signature 122 139 7.2E-32 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VMUT_1969 21661cf39634073020b830e0f54f430f 298 PRINTS PR00101 Aspartate carbamoyltransferase signature 274 288 7.2E-32 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VMUT_1969 21661cf39634073020b830e0f54f430f 298 PRINTS PR00101 Aspartate carbamoyltransferase signature 213 222 7.2E-32 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VMUT_1969 21661cf39634073020b830e0f54f430f 298 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 39 46 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VMUT_1969 21661cf39634073020b830e0f54f430f 298 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 295 33.774 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VMUT_1969 21661cf39634073020b830e0f54f430f 298 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 258 281 2.0E-22 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VMUT_1969 21661cf39634073020b830e0f54f430f 298 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 39 58 2.0E-22 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VMUT_1969 21661cf39634073020b830e0f54f430f 298 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 248 257 2.0E-22 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VMUT_1969 21661cf39634073020b830e0f54f430f 298 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 123 134 2.0E-22 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VMUT_1969 21661cf39634073020b830e0f54f430f 298 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 135 3.0E-41 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 VMUT_2311 e329e55bdcf26d1d5d43008eb1aeff20 389 SUPERFAMILY SSF103473 8 380 4.97E-37 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_2311 e329e55bdcf26d1d5d43008eb1aeff20 389 Pfam PF07690 Major Facilitator Superfamily 8 336 6.7E-21 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_2311 e329e55bdcf26d1d5d43008eb1aeff20 389 Gene3D G3DSA:1.20.1250.20 1 382 1.2E-30 T 23-10-2018 VMUT_1788 27bad0a8721c505e888595ed6bfa824d 621 Pfam PF03129 Anticodon binding domain 506 596 5.5E-21 T 23-10-2018 IPR004154 Anticodon-binding VMUT_1788 27bad0a8721c505e888595ed6bfa824d 621 ProDom PD016189 SYNTHETASE LIGASE THREONYL-TRNA AMINOACYL-TRNA NUCLEOTIDE-BINDING BIOSYNTHESIS ATP-BINDING ZINC METAL-BINDING THRRS 1 131 1.0E-28 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 VMUT_1788 27bad0a8721c505e888595ed6bfa824d 621 SUPERFAMILY SSF52954 497 606 3.17E-27 T 23-10-2018 VMUT_1788 27bad0a8721c505e888595ed6bfa824d 621 SUPERFAMILY SSF55681 189 513 3.08E-47 T 23-10-2018 VMUT_1788 27bad0a8721c505e888595ed6bfa824d 621 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 35 600 25.837 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 VMUT_1788 27bad0a8721c505e888595ed6bfa824d 621 Pfam PF08915 Archaea-specific editing domain of threonyl-tRNA synthetase 1 138 5.2E-46 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 VMUT_1788 27bad0a8721c505e888595ed6bfa824d 621 Gene3D G3DSA:3.40.50.800 497 604 2.2E-29 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily VMUT_1788 27bad0a8721c505e888595ed6bfa824d 621 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 280 484 1.5E-16 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_1788 27bad0a8721c505e888595ed6bfa824d 621 Gene3D G3DSA:3.50.80.10 1 139 9.5E-47 T 23-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily VMUT_1788 27bad0a8721c505e888595ed6bfa824d 621 Gene3D G3DSA:3.30.930.10 209 486 1.4E-49 T 23-10-2018 VMUT_1788 27bad0a8721c505e888595ed6bfa824d 621 PRINTS PR01047 Threonyl-tRNA synthetase signature 291 319 6.7E-24 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 VMUT_1788 27bad0a8721c505e888595ed6bfa824d 621 PRINTS PR01047 Threonyl-tRNA synthetase signature 421 449 6.7E-24 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 VMUT_1788 27bad0a8721c505e888595ed6bfa824d 621 PRINTS PR01047 Threonyl-tRNA synthetase signature 464 477 6.7E-24 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 VMUT_1788 27bad0a8721c505e888595ed6bfa824d 621 PRINTS PR01047 Threonyl-tRNA synthetase signature 499 511 6.7E-24 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 VMUT_1788 27bad0a8721c505e888595ed6bfa824d 621 PRINTS PR01047 Threonyl-tRNA synthetase signature 324 347 6.7E-24 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 VMUT_1434 de5bbaefba30a4a34af87e990716d81e 366 ProSitePatterns PS00787 Chorismate synthase signature 1. 15 30 - T 23-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 VMUT_1434 de5bbaefba30a4a34af87e990716d81e 366 Hamap MF_00300 Chorismate synthase [aroC]. 9 362 34.045 T 23-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 VMUT_1434 de5bbaefba30a4a34af87e990716d81e 366 PIRSF PIRSF001456 2 365 4.3E-135 T 23-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 VMUT_1434 de5bbaefba30a4a34af87e990716d81e 366 Pfam PF01264 Chorismate synthase 9 355 1.4E-116 T 23-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 VMUT_1434 de5bbaefba30a4a34af87e990716d81e 366 Gene3D G3DSA:3.60.150.10 1 365 4.1E-124 T 23-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 VMUT_1434 de5bbaefba30a4a34af87e990716d81e 366 SUPERFAMILY SSF103263 3 356 3.92E-119 T 23-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 VMUT_1434 de5bbaefba30a4a34af87e990716d81e 366 TIGRFAM TIGR00033 aroC: chorismate synthase 9 356 1.8E-118 T 23-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 VMUT_1871 e6aee1eef8c0da143b815a6ab641d737 350 Gene3D G3DSA:3.40.50.300 163 344 8.9E-42 T 23-10-2018 VMUT_1871 e6aee1eef8c0da143b815a6ab641d737 350 Pfam PF06858 Nucleolar GTP-binding protein 1 (NOG1) 238 293 4.4E-21 T 23-10-2018 IPR010674 Nucleolar GTP-binding protein 1, Rossman-fold domain GO:0005525 VMUT_1871 e6aee1eef8c0da143b815a6ab641d737 350 SUPERFAMILY SSF52540 164 337 1.49E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1871 e6aee1eef8c0da143b815a6ab641d737 350 Gene3D G3DSA:1.20.120.1190 7 162 6.4E-34 T 23-10-2018 VMUT_1871 e6aee1eef8c0da143b815a6ab641d737 350 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 193 211 1.9E-10 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 VMUT_1871 e6aee1eef8c0da143b815a6ab641d737 350 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 221 236 1.9E-10 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 VMUT_1871 e6aee1eef8c0da143b815a6ab641d737 350 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 172 192 1.9E-10 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 VMUT_1675 3843000efe6bc1f8214456e599731d34 458 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 4 312 4.3E-55 T 23-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 VMUT_1675 3843000efe6bc1f8214456e599731d34 458 Gene3D G3DSA:3.50.50.60 2 449 1.2E-133 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_1675 3843000efe6bc1f8214456e599731d34 458 Pfam PF01134 Glucose inhibited division protein A 5 35 8.8E-6 T 23-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 VMUT_1675 3843000efe6bc1f8214456e599731d34 458 SUPERFAMILY SSF51905 3 357 3.06E-36 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_1675 3843000efe6bc1f8214456e599731d34 458 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 4.0E-9 T 23-10-2018 VMUT_1675 3843000efe6bc1f8214456e599731d34 458 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 4.0E-9 T 23-10-2018 VMUT_1675 3843000efe6bc1f8214456e599731d34 458 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 277 292 4.0E-9 T 23-10-2018 VMUT_1675 3843000efe6bc1f8214456e599731d34 458 Pfam PF04820 Tryptophan halogenase 88 180 2.2E-4 T 23-10-2018 IPR006905 Flavin-dependent halogenase VMUT_1349 22f4c8a788be9106f9fa71d242eccb91 687 SUPERFAMILY SSF53850 59 655 1.55E-72 T 23-10-2018 VMUT_1349 22f4c8a788be9106f9fa71d242eccb91 687 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 100 570 8.8E-61 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain VMUT_1349 22f4c8a788be9106f9fa71d242eccb91 687 Gene3D G3DSA:3.10.105.10 391 631 2.9E-22 T 23-10-2018 VMUT_1349 22f4c8a788be9106f9fa71d242eccb91 687 PIRSF PIRSF002741 35 662 6.2E-40 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 VMUT_0947 999d40e9db626154c784237eb015b6de 484 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 370 478 2.1E-27 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 VMUT_0947 999d40e9db626154c784237eb015b6de 484 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 59 69 - T 23-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 VMUT_0947 999d40e9db626154c784237eb015b6de 484 Gene3D G3DSA:3.50.50.60 172 298 1.6E-83 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0947 999d40e9db626154c784237eb015b6de 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 305 7.4E-33 T 23-10-2018 VMUT_0947 999d40e9db626154c784237eb015b6de 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 314 336 7.4E-33 T 23-10-2018 VMUT_0947 999d40e9db626154c784237eb015b6de 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 201 219 7.4E-33 T 23-10-2018 VMUT_0947 999d40e9db626154c784237eb015b6de 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 26 45 7.4E-33 T 23-10-2018 VMUT_0947 999d40e9db626154c784237eb015b6de 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 178 7.4E-33 T 23-10-2018 VMUT_0947 999d40e9db626154c784237eb015b6de 484 SUPERFAMILY SSF55424 368 481 5.33E-33 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 VMUT_0947 999d40e9db626154c784237eb015b6de 484 SUPERFAMILY SSF51905 23 392 1.76E-49 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0947 999d40e9db626154c784237eb015b6de 484 Gene3D G3DSA:3.50.50.60 24 347 1.6E-83 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0947 999d40e9db626154c784237eb015b6de 484 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 24 348 1.9E-54 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VMUT_0947 999d40e9db626154c784237eb015b6de 484 PIRSF PIRSF000350 10 483 4.0E-60 T 23-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 VMUT_0947 999d40e9db626154c784237eb015b6de 484 Gene3D G3DSA:3.30.390.30 368 483 5.1E-35 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 VMUT_0947 999d40e9db626154c784237eb015b6de 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 58 73 1.3E-53 T 23-10-2018 VMUT_0947 999d40e9db626154c784237eb015b6de 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 201 226 1.3E-53 T 23-10-2018 VMUT_0947 999d40e9db626154c784237eb015b6de 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 453 473 1.3E-53 T 23-10-2018 VMUT_0947 999d40e9db626154c784237eb015b6de 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 329 336 1.3E-53 T 23-10-2018 VMUT_0947 999d40e9db626154c784237eb015b6de 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 25 47 1.3E-53 T 23-10-2018 VMUT_0947 999d40e9db626154c784237eb015b6de 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 290 304 1.3E-53 T 23-10-2018 VMUT_0947 999d40e9db626154c784237eb015b6de 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 366 387 1.3E-53 T 23-10-2018 VMUT_0947 999d40e9db626154c784237eb015b6de 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 446 1.3E-53 T 23-10-2018 VMUT_0947 999d40e9db626154c784237eb015b6de 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 163 172 1.3E-53 T 23-10-2018 VMUT_0713 8b5c0b35164e52768bef97acc1cf132b 300 Pfam PF08443 RimK-like ATP-grasp domain 109 294 2.9E-33 T 23-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 VMUT_0713 8b5c0b35164e52768bef97acc1cf132b 300 Gene3D G3DSA:3.30.470.80 193 300 3.4E-33 T 23-10-2018 VMUT_0713 8b5c0b35164e52768bef97acc1cf132b 300 Gene3D G3DSA:3.40.50.20 14 125 3.6E-8 T 23-10-2018 VMUT_0713 8b5c0b35164e52768bef97acc1cf132b 300 SUPERFAMILY SSF56059 111 298 1.5E-44 T 23-10-2018 VMUT_0713 8b5c0b35164e52768bef97acc1cf132b 300 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 74 293 1.8E-55 T 23-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 VMUT_1517 40933dbe30a926c744227359ff07a65f 301 SUPERFAMILY SSF53850 36 215 1.02E-40 T 23-10-2018 VMUT_1517 40933dbe30a926c744227359ff07a65f 301 Gene3D G3DSA:3.40.190.10 38 207 1.8E-39 T 23-10-2018 VMUT_1517 40933dbe30a926c744227359ff07a65f 301 Pfam PF00800 Prephenate dehydratase 36 211 2.9E-42 T 23-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 VMUT_1517 40933dbe30a926c744227359ff07a65f 301 Gene3D G3DSA:3.30.70.260 211 299 2.2E-24 T 23-10-2018 VMUT_1517 40933dbe30a926c744227359ff07a65f 301 PIRSF PIRSF001500 8 299 7.4E-65 T 23-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 VMUT_1517 40933dbe30a926c744227359ff07a65f 301 Gene3D G3DSA:3.40.190.10 116 199 1.8E-39 T 23-10-2018 VMUT_1517 40933dbe30a926c744227359ff07a65f 301 SUPERFAMILY SSF55021 211 296 1.58E-21 T 23-10-2018 VMUT_1565 01e4e2712b3d60ed3f10f0fb58d24ebc 455 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 5 445 1.3E-126 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VMUT_1565 01e4e2712b3d60ed3f10f0fb58d24ebc 455 Gene3D G3DSA:3.40.1380.20 331 445 4.0E-25 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VMUT_1565 01e4e2712b3d60ed3f10f0fb58d24ebc 455 Gene3D G3DSA:2.40.33.10 67 160 1.0E-101 T 23-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VMUT_1565 01e4e2712b3d60ed3f10f0fb58d24ebc 455 SUPERFAMILY SSF50800 67 159 1.59E-10 T 23-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily VMUT_1565 01e4e2712b3d60ed3f10f0fb58d24ebc 455 Pfam PF02887 Pyruvate kinase, alpha/beta domain 344 442 1.2E-15 T 23-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VMUT_1565 01e4e2712b3d60ed3f10f0fb58d24ebc 455 SUPERFAMILY SSF52935 315 444 7.48E-25 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VMUT_1565 01e4e2712b3d60ed3f10f0fb58d24ebc 455 Pfam PF00224 Pyruvate kinase, barrel domain 5 332 7.7E-84 T 23-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VMUT_1565 01e4e2712b3d60ed3f10f0fb58d24ebc 455 PRINTS PR01050 Pyruvate kinase family signature 286 304 1.6E-50 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VMUT_1565 01e4e2712b3d60ed3f10f0fb58d24ebc 455 PRINTS PR01050 Pyruvate kinase family signature 209 235 1.6E-50 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VMUT_1565 01e4e2712b3d60ed3f10f0fb58d24ebc 455 PRINTS PR01050 Pyruvate kinase family signature 261 285 1.6E-50 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VMUT_1565 01e4e2712b3d60ed3f10f0fb58d24ebc 455 PRINTS PR01050 Pyruvate kinase family signature 178 192 1.6E-50 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VMUT_1565 01e4e2712b3d60ed3f10f0fb58d24ebc 455 PRINTS PR01050 Pyruvate kinase family signature 56 72 1.6E-50 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VMUT_1565 01e4e2712b3d60ed3f10f0fb58d24ebc 455 PRINTS PR01050 Pyruvate kinase family signature 236 260 1.6E-50 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VMUT_1565 01e4e2712b3d60ed3f10f0fb58d24ebc 455 PRINTS PR01050 Pyruvate kinase family signature 305 321 1.6E-50 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VMUT_1565 01e4e2712b3d60ed3f10f0fb58d24ebc 455 Gene3D G3DSA:3.20.20.60 7 321 1.0E-101 T 23-10-2018 VMUT_1565 01e4e2712b3d60ed3f10f0fb58d24ebc 455 SUPERFAMILY SSF51621 3 335 5.23E-71 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 VMUT_1090 f0f13f47a01c51814c75e3e0fdd3ee40 385 Gene3D G3DSA:3.40.50.2000 23 378 7.6E-34 T 23-10-2018 VMUT_1090 f0f13f47a01c51814c75e3e0fdd3ee40 385 Gene3D G3DSA:3.40.50.2000 191 369 7.6E-34 T 23-10-2018 VMUT_1090 f0f13f47a01c51814c75e3e0fdd3ee40 385 Pfam PF00534 Glycosyl transferases group 1 203 362 9.2E-20 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 VMUT_1090 f0f13f47a01c51814c75e3e0fdd3ee40 385 SUPERFAMILY SSF53756 12 380 1.36E-45 T 23-10-2018 VMUT_0905 db3fc8932d393c344141b1d64a7eeb47 353 Gene3D G3DSA:3.90.105.20 117 196 1.1E-55 T 23-10-2018 VMUT_0905 db3fc8932d393c344141b1d64a7eeb47 353 Hamap MF_00280 50S ribosomal protein L10 [rpl10]. 14 294 31.062 T 23-10-2018 IPR022909 50S ribosomal protein L10, archaea VMUT_0905 db3fc8932d393c344141b1d64a7eeb47 353 SUPERFAMILY SSF160369 17 147 7.45E-19 T 23-10-2018 VMUT_0905 db3fc8932d393c344141b1d64a7eeb47 353 Pfam PF00466 Ribosomal protein L10 18 112 1.3E-20 T 23-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 VMUT_0905 db3fc8932d393c344141b1d64a7eeb47 353 Gene3D G3DSA:3.30.70.1730 28 220 1.1E-55 T 23-10-2018 VMUT_0856 e395054a31a96112f1f826415159400f 394 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 83 108 - T 23-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 VMUT_0856 e395054a31a96112f1f826415159400f 394 Pfam PF13378 Enolase C-terminal domain-like 152 378 8.6E-61 T 23-10-2018 IPR029065 Enolase C-terminal domain-like VMUT_0856 e395054a31a96112f1f826415159400f 394 Gene3D G3DSA:3.20.20.120 102 370 4.2E-112 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VMUT_0856 e395054a31a96112f1f826415159400f 394 SUPERFAMILY SSF54826 4 108 1.77E-22 T 23-10-2018 VMUT_0856 e395054a31a96112f1f826415159400f 394 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 16 108 5.4E-12 T 23-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain VMUT_0856 e395054a31a96112f1f826415159400f 394 SMART SM00922 147 259 4.2E-20 T 23-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal VMUT_0856 e395054a31a96112f1f826415159400f 394 SUPERFAMILY SSF51604 96 384 3.8E-77 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VMUT_0856 e395054a31a96112f1f826415159400f 394 Gene3D G3DSA:3.30.390.10 6 379 4.2E-112 T 23-10-2018 IPR029017 Enolase-like, N-terminal VMUT_1532 61db1b6d1db1ed585d0e07c4f09e272d 406 Pfam PF07690 Major Facilitator Superfamily 12 351 4.6E-21 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_1532 61db1b6d1db1ed585d0e07c4f09e272d 406 SUPERFAMILY SSF103473 1 391 8.24E-45 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_1532 61db1b6d1db1ed585d0e07c4f09e272d 406 Gene3D G3DSA:1.20.1250.20 1 403 1.1E-43 T 23-10-2018 VMUT_1471 016c64e836dab4aa67c7bf6f626fcb3c 356 Pfam PF09376 NurA domain 59 321 4.1E-9 T 23-10-2018 IPR018977 NurA domain VMUT_1471 016c64e836dab4aa67c7bf6f626fcb3c 356 SMART SM00933 58 322 1.3E-15 T 23-10-2018 IPR018977 NurA domain VMUT_1471 016c64e836dab4aa67c7bf6f626fcb3c 356 SUPERFAMILY SSF56003 131 303 9.87E-5 T 23-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 TIGRFAM TIGR01647 ATPase-IIIA_H: plasma-membrane proton-efflux P-type ATPase 1 718 9.6E-212 T 23-10-2018 IPR006534 P-type ATPase, subfamily IIIA GO:0008553|GO:0016021|GO:0120029 KEGG: 00190+3.6.3.6 VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 260 266 - T 23-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 535 560 5.1E-29 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 372 390 5.1E-29 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 476 492 5.1E-29 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 504 520 5.1E-29 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 673 694 5.1E-29 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 Gene3D G3DSA:3.40.50.1000 404 451 1.3E-7 T 23-10-2018 IPR023214 HAD superfamily VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 SUPERFAMILY SSF81665 1 748 6.41E-48 T 23-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 SUPERFAMILY SSF81660 264 413 6.15E-17 T 23-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 Gene3D G3DSA:1.20.1110.10 159 272 1.2E-11 T 23-10-2018 VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 466 593 2.7E-28 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 27 448 1.2E-54 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 Gene3D G3DSA:2.70.150.10 29 158 3.1E-33 T 23-10-2018 VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 SUPERFAMILY SSF56784 256 594 1.38E-41 T 23-10-2018 IPR036412 HAD-like superfamily VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 Gene3D G3DSA:1.20.1110.10 452 760 2.8E-47 T 23-10-2018 VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 527 539 3.1E-38 T 23-10-2018 VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 504 523 3.1E-38 T 23-10-2018 VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 105 119 3.1E-38 T 23-10-2018 VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 424 434 3.1E-38 T 23-10-2018 VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 402 413 3.1E-38 T 23-10-2018 VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 258 272 3.1E-38 T 23-10-2018 VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 Pfam PF00122 E1-E2 ATPase 57 238 2.8E-51 T 23-10-2018 VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 Pfam PF00702 haloacid dehalogenase-like hydrolase 255 517 9.2E-22 T 23-10-2018 VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 Gene3D G3DSA:3.40.1110.10 273 403 8.3E-30 T 23-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 VMUT_0483 530d12551460efc2979e25b0a4f0d531 766 SUPERFAMILY SSF81653 58 155 7.98E-30 T 23-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 VMUT_1798 104264dfb414dd1fde6b3671109ed4b0 176 Hamap MF_00699 Probable Brix domain-containing ribosomal biogenesis protein. 1 168 21.9 T 23-10-2018 IPR023548 Probable Brix domain-containing ribosomal biogenesis protein VMUT_1798 104264dfb414dd1fde6b3671109ed4b0 176 Gene3D G3DSA:3.40.50.10480 1 164 1.8E-19 T 23-10-2018 VMUT_1798 104264dfb414dd1fde6b3671109ed4b0 176 SUPERFAMILY SSF52954 1 161 4.12E-16 T 23-10-2018 VMUT_0455 afc367f2e941bc6eae8a2c12048aedd2 329 Pfam PF00005 ABC transporter 26 183 5.5E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_0455 afc367f2e941bc6eae8a2c12048aedd2 329 SMART SM00382 35 240 6.3E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0455 afc367f2e941bc6eae8a2c12048aedd2 329 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 294 6.4E-19 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VMUT_0455 afc367f2e941bc6eae8a2c12048aedd2 329 Gene3D G3DSA:3.40.50.300 4 329 1.2E-97 T 23-10-2018 VMUT_0455 afc367f2e941bc6eae8a2c12048aedd2 329 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 327 1.6E-25 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VMUT_0455 afc367f2e941bc6eae8a2c12048aedd2 329 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VMUT_0455 afc367f2e941bc6eae8a2c12048aedd2 329 SUPERFAMILY SSF52540 35 295 5.32E-68 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1451 e655dc441f3ee4d0b6b46c181403e6cc 382 Gene3D G3DSA:1.10.10.10 303 362 1.1E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_1451 e655dc441f3ee4d0b6b46c181403e6cc 382 Gene3D G3DSA:3.40.50.1100 243 302 1.3E-5 T 23-10-2018 VMUT_1451 e655dc441f3ee4d0b6b46c181403e6cc 382 Gene3D G3DSA:3.40.50.1100 49 230 1.8E-24 T 23-10-2018 VMUT_1451 e655dc441f3ee4d0b6b46c181403e6cc 382 Gene3D G3DSA:3.40.50.1100 89 169 1.8E-24 T 23-10-2018 VMUT_1451 e655dc441f3ee4d0b6b46c181403e6cc 382 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 62 296 4.3E-19 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme VMUT_1451 e655dc441f3ee4d0b6b46c181403e6cc 382 SUPERFAMILY SSF53686 15 312 1.7E-26 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme VMUT_1451 e655dc441f3ee4d0b6b46c181403e6cc 382 SUPERFAMILY SSF46785 311 372 6.25E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0061 4c738e41f96a83db3a84d2154d6403f7 205 PRINTS PR00141 Proteasome component signature 17 32 2.2E-7 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 VMUT_0061 4c738e41f96a83db3a84d2154d6403f7 205 PRINTS PR00141 Proteasome component signature 138 149 2.2E-7 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 VMUT_0061 4c738e41f96a83db3a84d2154d6403f7 205 PRINTS PR00141 Proteasome component signature 149 160 2.2E-7 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 VMUT_0061 4c738e41f96a83db3a84d2154d6403f7 205 PRINTS PR00141 Proteasome component signature 174 185 2.2E-7 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 VMUT_0061 4c738e41f96a83db3a84d2154d6403f7 205 SUPERFAMILY SSF56235 10 198 9.36E-57 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VMUT_0061 4c738e41f96a83db3a84d2154d6403f7 205 Pfam PF00227 Proteasome subunit 10 188 2.4E-50 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 VMUT_0061 4c738e41f96a83db3a84d2154d6403f7 205 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 13 60 - T 23-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 VMUT_0061 4c738e41f96a83db3a84d2154d6403f7 205 Gene3D G3DSA:3.60.20.10 10 201 5.0E-58 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VMUT_0061 4c738e41f96a83db3a84d2154d6403f7 205 Hamap MF_02113_A Proteasome subunit beta [prcB]. 5 201 34.384 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 VMUT_0133 adbea9ebf370151b434214029a982a45 425 PRINTS PR00758 Arsenical pump membrane protein signature 181 204 4.5E-10 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 VMUT_0133 adbea9ebf370151b434214029a982a45 425 PRINTS PR00758 Arsenical pump membrane protein signature 106 130 4.5E-10 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 VMUT_0133 adbea9ebf370151b434214029a982a45 425 PRINTS PR00758 Arsenical pump membrane protein signature 281 305 4.5E-10 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 VMUT_0133 adbea9ebf370151b434214029a982a45 425 PRINTS PR00758 Arsenical pump membrane protein signature 220 245 4.5E-10 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 VMUT_0133 adbea9ebf370151b434214029a982a45 425 Pfam PF03600 Citrate transporter 34 351 1.6E-36 T 23-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 VMUT_0766 7f17779d2f01292cdc3ce9b051164b55 72 Pfam PF01423 LSM domain 7 70 2.2E-20 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type VMUT_0766 7f17779d2f01292cdc3ce9b051164b55 72 Gene3D G3DSA:2.30.30.100 1 71 1.4E-21 T 23-10-2018 VMUT_0766 7f17779d2f01292cdc3ce9b051164b55 72 SMART SM00651 6 70 3.5E-20 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type VMUT_0766 7f17779d2f01292cdc3ce9b051164b55 72 SUPERFAMILY SSF50182 7 70 1.15E-19 T 23-10-2018 IPR010920 LSM domain superfamily VMUT_2228 930eeb42eef1fbc683217fddd6295fb3 296 Gene3D G3DSA:3.20.20.70 17 206 4.0E-15 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_2228 930eeb42eef1fbc683217fddd6295fb3 296 Pfam PF13394 4Fe-4S single cluster domain 20 108 8.7E-7 T 23-10-2018 VMUT_2228 930eeb42eef1fbc683217fddd6295fb3 296 Pfam PF04055 Radical SAM superfamily 22 130 8.1E-11 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_2228 930eeb42eef1fbc683217fddd6295fb3 296 SUPERFAMILY SSF102114 19 191 2.35E-20 T 23-10-2018 VMUT_2228 930eeb42eef1fbc683217fddd6295fb3 296 SMART SM00729 16 202 0.0039 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VMUT_1361 39c6858d39e3ac82033e1cbe67b74cb0 468 SUPERFAMILY SSF53067 5 234 2.99E-45 T 23-10-2018 VMUT_1361 39c6858d39e3ac82033e1cbe67b74cb0 468 Gene3D G3DSA:3.30.420.40 2 232 4.9E-47 T 23-10-2018 VMUT_1361 39c6858d39e3ac82033e1cbe67b74cb0 468 PIRSF PIRSF000538 1 464 1.6E-63 T 23-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 VMUT_1361 39c6858d39e3ac82033e1cbe67b74cb0 468 SUPERFAMILY SSF53067 233 454 1.11E-33 T 23-10-2018 VMUT_1361 39c6858d39e3ac82033e1cbe67b74cb0 468 Gene3D G3DSA:3.30.420.40 233 462 3.8E-40 T 23-10-2018 VMUT_1361 39c6858d39e3ac82033e1cbe67b74cb0 468 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 267 418 1.1E-21 T 23-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 VMUT_1361 39c6858d39e3ac82033e1cbe67b74cb0 468 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 214 1.8E-25 T 23-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 VMUT_0401 ae64b2175281fdb141dc23810dbd2b72 152 Pfam PF03692 Putative zinc- or iron-chelating domain 23 112 1.8E-17 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein VMUT_1445 08b7b7c54a6a1a2151c3120be0b6d27b 724 Pfam PF05317 Thermopsin 145 398 6.9E-72 T 23-10-2018 IPR007981 Peptidase A5, thermopsin VMUT_0890 62bbb94d5e5fd22883f1fe719f3e19d5 397 Gene3D G3DSA:1.10.8.60 10 277 2.0E-77 T 23-10-2018 VMUT_0890 62bbb94d5e5fd22883f1fe719f3e19d5 397 SUPERFAMILY SSF46785 289 393 9.98E-27 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0890 62bbb94d5e5fd22883f1fe719f3e19d5 397 SMART SM00382 44 212 2.1E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0890 62bbb94d5e5fd22883f1fe719f3e19d5 397 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 4 374 6.3E-79 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea VMUT_0890 62bbb94d5e5fd22883f1fe719f3e19d5 397 SMART SM01074 302 386 1.6E-20 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 VMUT_0890 62bbb94d5e5fd22883f1fe719f3e19d5 397 Pfam PF13401 AAA domain 49 180 1.1E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0890 62bbb94d5e5fd22883f1fe719f3e19d5 397 Pfam PF09079 CDC6, C terminal winged helix domain 302 381 4.4E-18 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 VMUT_0890 62bbb94d5e5fd22883f1fe719f3e19d5 397 Gene3D G3DSA:1.10.10.10 285 395 6.7E-32 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_0890 62bbb94d5e5fd22883f1fe719f3e19d5 397 Hamap MF_01407 ORC1-type DNA replication protein. 1 386 24.52 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea VMUT_0890 62bbb94d5e5fd22883f1fe719f3e19d5 397 Gene3D G3DSA:3.40.50.300 20 199 2.0E-77 T 23-10-2018 VMUT_0890 62bbb94d5e5fd22883f1fe719f3e19d5 397 SUPERFAMILY SSF52540 4 281 1.12E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1283 9935e9a8a7eae0dcafe179e3ceffee0b 661 SMART SM00852 193 333 2.5E-38 T 23-10-2018 IPR001453 MoaB/Mog domain VMUT_1283 9935e9a8a7eae0dcafe179e3ceffee0b 661 SUPERFAMILY SSF53850 446 651 2.47E-20 T 23-10-2018 VMUT_1283 9935e9a8a7eae0dcafe179e3ceffee0b 661 Pfam PF03454 MoeA C-terminal region (domain IV) 345 415 3.6E-15 T 23-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VMUT_1283 9935e9a8a7eae0dcafe179e3ceffee0b 661 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 190 329 9.6E-30 T 23-10-2018 IPR001453 MoaB/Mog domain VMUT_1283 9935e9a8a7eae0dcafe179e3ceffee0b 661 SUPERFAMILY SSF53218 188 335 7.59E-38 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily VMUT_1283 9935e9a8a7eae0dcafe179e3ceffee0b 661 Gene3D G3DSA:3.90.105.10 37 187 3.1E-104 T 23-10-2018 VMUT_1283 9935e9a8a7eae0dcafe179e3ceffee0b 661 Gene3D G3DSA:2.40.340.10 342 416 6.0E-19 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VMUT_1283 9935e9a8a7eae0dcafe179e3ceffee0b 661 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 266 301 - T 23-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 VMUT_1283 9935e9a8a7eae0dcafe179e3ceffee0b 661 Gene3D G3DSA:3.40.980.10 188 332 3.1E-104 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily VMUT_1283 9935e9a8a7eae0dcafe179e3ceffee0b 661 Pfam PF03453 MoeA N-terminal region (domain I and II) 15 180 3.5E-44 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VMUT_1283 9935e9a8a7eae0dcafe179e3ceffee0b 661 SUPERFAMILY SSF63867 343 416 8.76E-15 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VMUT_1283 9935e9a8a7eae0dcafe179e3ceffee0b 661 Gene3D G3DSA:2.170.190.11 58 154 3.1E-104 T 23-10-2018 VMUT_1283 9935e9a8a7eae0dcafe179e3ceffee0b 661 Pfam PF12727 PBP superfamily domain 445 632 2.6E-62 T 23-10-2018 IPR024370 PBP domain VMUT_1283 9935e9a8a7eae0dcafe179e3ceffee0b 661 Pfam PF00994 Probable molybdopterin binding domain 194 332 1.8E-25 T 23-10-2018 IPR001453 MoaB/Mog domain VMUT_1283 9935e9a8a7eae0dcafe179e3ceffee0b 661 SUPERFAMILY SSF63882 13 188 4.32E-53 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VMUT_1283 9935e9a8a7eae0dcafe179e3ceffee0b 661 Gene3D G3DSA:3.40.190.10 504 611 1.9E-10 T 23-10-2018 VMUT_2212 fc49cd4c4a013bf71904b5c1367b0866 404 SUPERFAMILY SSF51905 6 384 1.29E-37 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_2212 fc49cd4c4a013bf71904b5c1367b0866 404 Pfam PF01266 FAD dependent oxidoreductase 8 380 1.0E-44 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VMUT_2212 fc49cd4c4a013bf71904b5c1367b0866 404 Gene3D G3DSA:3.50.50.60 8 375 2.0E-70 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_2212 fc49cd4c4a013bf71904b5c1367b0866 404 Gene3D G3DSA:3.30.9.10 94 342 2.0E-70 T 23-10-2018 VMUT_1658 2d98b872e801d26cdcf8f8faf33922c0 250 SUPERFAMILY SSF89550 31 230 3.14E-40 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 VMUT_1658 2d98b872e801d26cdcf8f8faf33922c0 250 Pfam PF13263 PHP-associated 172 225 3.7E-13 T 23-10-2018 VMUT_1658 2d98b872e801d26cdcf8f8faf33922c0 250 Pfam PF02811 PHP domain 33 117 3.0E-6 T 23-10-2018 IPR004013 PHP domain GO:0003824 VMUT_1658 2d98b872e801d26cdcf8f8faf33922c0 250 Gene3D G3DSA:3.20.20.140 29 232 6.4E-38 T 23-10-2018 VMUT_1658 2d98b872e801d26cdcf8f8faf33922c0 250 SMART SM00481 32 103 2.2E-13 T 23-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal VMUT_1620 1473e42f474bd88461b9768d0fb29416 146 Gene3D G3DSA:3.30.428.10 6 141 1.8E-43 T 23-10-2018 IPR036265 HIT-like superfamily VMUT_1620 1473e42f474bd88461b9768d0fb29416 146 Pfam PF01230 HIT domain 19 112 1.8E-28 T 23-10-2018 IPR001310 Histidine triad (HIT) protein VMUT_1620 1473e42f474bd88461b9768d0fb29416 146 PRINTS PR00332 Histidine triad family signature 100 110 2.9E-14 T 23-10-2018 IPR001310 Histidine triad (HIT) protein VMUT_1620 1473e42f474bd88461b9768d0fb29416 146 PRINTS PR00332 Histidine triad family signature 12 28 2.9E-14 T 23-10-2018 IPR001310 Histidine triad (HIT) protein VMUT_1620 1473e42f474bd88461b9768d0fb29416 146 PRINTS PR00332 Histidine triad family signature 33 51 2.9E-14 T 23-10-2018 IPR001310 Histidine triad (HIT) protein VMUT_1620 1473e42f474bd88461b9768d0fb29416 146 ProSitePatterns PS00892 HIT domain signature. 93 111 - T 23-10-2018 IPR019808 Histidine triad, conserved site VMUT_1620 1473e42f474bd88461b9768d0fb29416 146 SUPERFAMILY SSF54197 9 126 2.27E-41 T 23-10-2018 IPR036265 HIT-like superfamily VMUT_0800 128f11c9c691b12ba482832bd7a73f54 623 SMART SM00488 8 254 7.6E-11 T 23-10-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 VMUT_0800 128f11c9c691b12ba482832bd7a73f54 623 SMART SM00382 34 262 0.0058 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0800 128f11c9c691b12ba482832bd7a73f54 623 SMART SM00491 456 591 1.6E-10 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 VMUT_0800 128f11c9c691b12ba482832bd7a73f54 623 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 208 217 - T 23-10-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site VMUT_0800 128f11c9c691b12ba482832bd7a73f54 623 Gene3D G3DSA:1.10.275.30 227 352 5.3E-92 T 23-10-2018 VMUT_0800 128f11c9c691b12ba482832bd7a73f54 623 Pfam PF06733 DEAD_2 70 230 1.7E-22 T 23-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 VMUT_0800 128f11c9c691b12ba482832bd7a73f54 623 Pfam PF06777 Helical and beta-bridge domain 247 422 2.1E-8 T 23-10-2018 IPR010643 Helical and beta-bridge domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-2564830|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 VMUT_0800 128f11c9c691b12ba482832bd7a73f54 623 Pfam PF13307 Helicase C-terminal domain 447 600 1.7E-24 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 VMUT_0800 128f11c9c691b12ba482832bd7a73f54 623 SUPERFAMILY SSF52540 38 603 6.6E-5 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0800 128f11c9c691b12ba482832bd7a73f54 623 Gene3D G3DSA:3.40.50.300 406 601 2.2E-42 T 23-10-2018 VMUT_0800 128f11c9c691b12ba482832bd7a73f54 623 SUPERFAMILY SSF52540 8 226 2.53E-15 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0800 128f11c9c691b12ba482832bd7a73f54 623 Gene3D G3DSA:3.40.50.300 18 391 5.3E-92 T 23-10-2018 VMUT_1582 5b077a8501b82e181caaf5dea4d512e7 205 SUPERFAMILY SSF56784 1 203 4.67E-27 T 23-10-2018 IPR036412 HAD-like superfamily VMUT_1582 5b077a8501b82e181caaf5dea4d512e7 205 Pfam PF08282 haloacid dehalogenase-like hydrolase 134 191 6.7E-9 T 23-10-2018 VMUT_1582 5b077a8501b82e181caaf5dea4d512e7 205 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 4 166 1.4E-16 T 23-10-2018 VMUT_1582 5b077a8501b82e181caaf5dea4d512e7 205 Gene3D G3DSA:3.40.50.1000 1 202 2.1E-28 T 23-10-2018 IPR023214 HAD superfamily VMUT_0205 5a920c148bac6059bf698aebb768e568 375 PIRSF PIRSF004930 15 373 8.7E-121 T 23-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 VMUT_0205 5a920c148bac6059bf698aebb768e568 375 SUPERFAMILY SSF55821 20 225 1.62E-64 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily VMUT_0205 5a920c148bac6059bf698aebb768e568 375 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 23 225 1.9E-58 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 VMUT_0205 5a920c148bac6059bf698aebb768e568 375 Gene3D G3DSA:3.40.50.11030 233 375 7.9E-38 T 23-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily VMUT_0205 5a920c148bac6059bf698aebb768e568 375 Pfam PF01300 Telomere recombination 38 215 1.3E-52 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 VMUT_0205 5a920c148bac6059bf698aebb768e568 375 Pfam PF03481 Putative GTP-binding controlling metal-binding 219 367 3.1E-22 T 23-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain VMUT_0205 5a920c148bac6059bf698aebb768e568 375 Gene3D G3DSA:3.90.870.10 17 230 3.5E-80 T 23-10-2018 VMUT_1659 48c9861cc28be3d232f573e42a507708 202 SUPERFAMILY SSF143447 2 196 4.45E-60 T 23-10-2018 IPR036071 AMMECR1 domain superfamily VMUT_1659 48c9861cc28be3d232f573e42a507708 202 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 2 176 6.3E-47 T 23-10-2018 IPR027623 AmmeMemoRadiSam system protein A VMUT_1659 48c9861cc28be3d232f573e42a507708 202 Hamap MF_00645 Protein . 2 174 31.94 T 23-10-2018 IPR023472 Uncharacterised protein family MJ0810 VMUT_1659 48c9861cc28be3d232f573e42a507708 202 Pfam PF01871 AMMECR1 2 176 1.7E-43 T 23-10-2018 IPR002733 AMMECR1 domain VMUT_1659 48c9861cc28be3d232f573e42a507708 202 Gene3D G3DSA:3.30.1490.150 98 172 9.7E-63 T 23-10-2018 VMUT_1659 48c9861cc28be3d232f573e42a507708 202 Gene3D G3DSA:3.30.700.20 2 184 9.7E-63 T 23-10-2018 IPR027485 AMMECR1, N-terminal VMUT_1659 48c9861cc28be3d232f573e42a507708 202 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 1 187 1.8E-55 T 23-10-2018 IPR023473 AMMECR1 VMUT_1381 1e69181c798c2ce2d27474bd52115469 552 Gene3D G3DSA:3.30.300.310 444 551 1.7E-33 T 23-10-2018 VMUT_1381 1e69181c798c2ce2d27474bd52115469 552 Gene3D G3DSA:3.40.50.12780 1 443 2.7E-109 T 23-10-2018 VMUT_1381 1e69181c798c2ce2d27474bd52115469 552 ProSitePatterns PS00455 Putative AMP-binding domain signature. 189 200 - T 23-10-2018 IPR020845 AMP-binding, conserved site VMUT_1381 1e69181c798c2ce2d27474bd52115469 552 Pfam PF13193 AMP-binding enzyme C-terminal domain 458 538 1.1E-20 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VMUT_1381 1e69181c798c2ce2d27474bd52115469 552 Pfam PF00501 AMP-binding enzyme 17 448 4.3E-80 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VMUT_1381 1e69181c798c2ce2d27474bd52115469 552 SUPERFAMILY SSF56801 5 548 2.75E-129 T 23-10-2018 VMUT_1783 3007c8ce1095f00c4ff18c345a53666d 784 Gene3D G3DSA:1.10.132.60 622 784 7.9E-41 T 23-10-2018 VMUT_1783 3007c8ce1095f00c4ff18c345a53666d 784 Gene3D G3DSA:3.30.342.10 6 150 2.7E-27 T 23-10-2018 VMUT_1783 3007c8ce1095f00c4ff18c345a53666d 784 SUPERFAMILY SSF53098 5 397 1.28E-73 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily VMUT_1783 3007c8ce1095f00c4ff18c345a53666d 784 Gene3D G3DSA:1.10.287.690 470 523 1.3E-59 T 23-10-2018 VMUT_1783 3007c8ce1095f00c4ff18c345a53666d 784 Pfam PF03104 DNA polymerase family B, exonuclease domain 27 291 2.2E-38 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VMUT_1783 3007c8ce1095f00c4ff18c345a53666d 784 SUPERFAMILY SSF56672 377 768 1.84E-111 T 23-10-2018 VMUT_1783 3007c8ce1095f00c4ff18c345a53666d 784 Pfam PF00136 DNA polymerase family B 363 762 1.2E-67 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VMUT_1783 3007c8ce1095f00c4ff18c345a53666d 784 SMART SM00486 167 573 3.5E-104 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VMUT_1783 3007c8ce1095f00c4ff18c345a53666d 784 Gene3D G3DSA:3.90.1600.10 407 609 1.3E-59 T 23-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VMUT_1783 3007c8ce1095f00c4ff18c345a53666d 784 Gene3D G3DSA:3.30.420.10 167 374 7.8E-47 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VMUT_1783 3007c8ce1095f00c4ff18c345a53666d 784 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 203 761 6.5E-82 T 23-10-2018 VMUT_1783 3007c8ce1095f00c4ff18c345a53666d 784 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 423 436 2.2E-11 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VMUT_1783 3007c8ce1095f00c4ff18c345a53666d 784 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 559 567 2.2E-11 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VMUT_1783 3007c8ce1095f00c4ff18c345a53666d 784 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 507 519 2.2E-11 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VMUT_1783 3007c8ce1095f00c4ff18c345a53666d 784 ProSitePatterns PS00116 DNA polymerase family B signature. 561 569 - T 23-10-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VMUT_2074 22249cddd253c2eaf8f9a2dd318bdaa8 279 PRINTS PR00069 Aldo-keto reductase signature 133 150 2.4E-20 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VMUT_2074 22249cddd253c2eaf8f9a2dd318bdaa8 279 PRINTS PR00069 Aldo-keto reductase signature 48 72 2.4E-20 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VMUT_2074 22249cddd253c2eaf8f9a2dd318bdaa8 279 PRINTS PR00069 Aldo-keto reductase signature 211 235 2.4E-20 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VMUT_2074 22249cddd253c2eaf8f9a2dd318bdaa8 279 PRINTS PR00069 Aldo-keto reductase signature 102 120 2.4E-20 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VMUT_2074 22249cddd253c2eaf8f9a2dd318bdaa8 279 SUPERFAMILY SSF51430 2 277 7.46E-84 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VMUT_2074 22249cddd253c2eaf8f9a2dd318bdaa8 279 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 133 150 - T 23-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 VMUT_2074 22249cddd253c2eaf8f9a2dd318bdaa8 279 Pfam PF00248 Aldo/keto reductase family 39 278 4.6E-59 T 23-10-2018 IPR023210 NADP-dependent oxidoreductase domain VMUT_2074 22249cddd253c2eaf8f9a2dd318bdaa8 279 PIRSF PIRSF000097 121 279 1.9E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VMUT_2074 22249cddd253c2eaf8f9a2dd318bdaa8 279 PIRSF PIRSF000097 4 123 1.4E-20 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VMUT_2074 22249cddd253c2eaf8f9a2dd318bdaa8 279 Gene3D G3DSA:3.20.20.100 1 278 2.0E-82 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VMUT_0323 6521fda390a7d660a2fc116936f71e06 348 Gene3D G3DSA:2.30.130.70 18 324 1.0E-133 T 23-10-2018 VMUT_0323 6521fda390a7d660a2fc116936f71e06 348 Pfam PF08068 DKCLD (NUC011) domain 9 56 3.0E-15 T 23-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 VMUT_0323 6521fda390a7d660a2fc116936f71e06 348 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 61 111 1.7E-14 T 23-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 VMUT_0323 6521fda390a7d660a2fc116936f71e06 348 SMART SM00359 244 318 2.5E-19 T 23-10-2018 IPR002478 PUA domain GO:0003723 VMUT_0323 6521fda390a7d660a2fc116936f71e06 348 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 175 240 4.9E-20 T 23-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 VMUT_0323 6521fda390a7d660a2fc116936f71e06 348 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 232 315 9.2E-9 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 VMUT_0323 6521fda390a7d660a2fc116936f71e06 348 SUPERFAMILY SSF88697 242 324 3.87E-21 T 23-10-2018 IPR015947 PUA-like superfamily VMUT_0323 6521fda390a7d660a2fc116936f71e06 348 Hamap MF_01081 Probable tRNA pseudouridine synthase B [truB]. 34 318 47.781 T 23-10-2018 IPR026326 Probable tRNA pseudouridine synthase B, archaeal GO:0006396 VMUT_0323 6521fda390a7d660a2fc116936f71e06 348 TIGRFAM TIGR00425 CBF5: putative rRNA pseudouridine synthase 11 328 2.3E-129 T 23-10-2018 IPR004802 tRNA pseudouridine synthase B family GO:0006396 Reactome: R-HSA-171319|Reactome: R-HSA-6790901 VMUT_0323 6521fda390a7d660a2fc116936f71e06 348 SUPERFAMILY SSF55120 6 241 2.26E-69 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 VMUT_0323 6521fda390a7d660a2fc116936f71e06 348 Pfam PF01472 PUA domain 244 317 4.3E-18 T 23-10-2018 IPR002478 PUA domain GO:0003723 VMUT_0323 6521fda390a7d660a2fc116936f71e06 348 Gene3D G3DSA:3.30.2350.10 34 236 1.0E-133 T 23-10-2018 VMUT_0323 6521fda390a7d660a2fc116936f71e06 348 SMART SM01136 8 57 1.5E-20 T 23-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 VMUT_0158 3f16ea068152bfc69b1b1a8ef8a726dd 98 Pfam PF10007 Uncharacterized protein conserved in archaea (DUF2250) 6 91 1.3E-33 T 23-10-2018 IPR019254 Protein of unknown function DUF2250 VMUT_0158 3f16ea068152bfc69b1b1a8ef8a726dd 98 Gene3D G3DSA:1.10.10.10 1 98 6.9E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_0158 3f16ea068152bfc69b1b1a8ef8a726dd 98 SUPERFAMILY SSF46785 3 61 1.64E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_1490 e8890161c88a0a59572019b3c243c9d3 325 TIGRFAM TIGR02582 cas7_TM1809: CRISPR type III-A/MTUBE-associated RAMP protein Csm3 21 277 6.2E-28 T 23-10-2018 IPR013412 CRISPR-associated RAMP Csm3 VMUT_1490 e8890161c88a0a59572019b3c243c9d3 325 Pfam PF03787 RAMP superfamily 63 276 2.3E-8 T 23-10-2018 IPR005537 CRISPR type III-associated RAMP protein VMUT_0578 c78a7bc8553ad6de6d9680ddf6b4273c 281 SUPERFAMILY SSF48150 6 250 1.02E-66 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 VMUT_0578 c78a7bc8553ad6de6d9680ddf6b4273c 281 Pfam PF09171 N-glycosylase/DNA lyase 11 254 2.9E-72 T 23-10-2018 IPR015254 N-glycosylase/DNA lyase-like GO:0003906|GO:0016799 VMUT_0578 c78a7bc8553ad6de6d9680ddf6b4273c 281 Gene3D G3DSA:1.10.1670.10 13 245 1.7E-56 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 VMUT_0578 c78a7bc8553ad6de6d9680ddf6b4273c 281 Gene3D G3DSA:1.10.340.30 27 167 1.7E-56 T 23-10-2018 VMUT_1318 d8a47ea388facd578953cdecf82f9f7b 893 SUPERFAMILY SSF56059 5 381 2.59E-120 T 23-10-2018 VMUT_1318 d8a47ea388facd578953cdecf82f9f7b 893 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 525 879 1.8E-77 T 23-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 VMUT_1318 d8a47ea388facd578953cdecf82f9f7b 893 SUPERFAMILY SSF51621 512 881 3.34E-104 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 VMUT_1318 d8a47ea388facd578953cdecf82f9f7b 893 Gene3D G3DSA:3.30.470.20 247 344 2.3E-37 T 23-10-2018 VMUT_1318 d8a47ea388facd578953cdecf82f9f7b 893 SUPERFAMILY SSF52009 388 513 1.57E-37 T 23-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 VMUT_1318 d8a47ea388facd578953cdecf82f9f7b 893 Gene3D G3DSA:1.20.80.30 113 199 1.7E-84 T 23-10-2018 VMUT_1318 d8a47ea388facd578953cdecf82f9f7b 893 Pfam PF00391 PEP-utilising enzyme, mobile domain 423 504 3.2E-25 T 23-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 VMUT_1318 d8a47ea388facd578953cdecf82f9f7b 893 Gene3D G3DSA:3.20.20.60 534 882 1.0E-128 T 23-10-2018 VMUT_1318 d8a47ea388facd578953cdecf82f9f7b 893 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 20 298 5.8E-35 T 23-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 VMUT_1318 d8a47ea388facd578953cdecf82f9f7b 893 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 305 359 2.9E-6 T 23-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 VMUT_1318 d8a47ea388facd578953cdecf82f9f7b 893 PIRSF PIRSF000853 4 887 0.0 T 23-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 VMUT_1318 d8a47ea388facd578953cdecf82f9f7b 893 Gene3D G3DSA:1.10.189.10 348 530 2.2E-66 T 23-10-2018 VMUT_1318 d8a47ea388facd578953cdecf82f9f7b 893 Gene3D G3DSA:3.30.1490.20 17 246 1.7E-84 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VMUT_1318 d8a47ea388facd578953cdecf82f9f7b 893 Gene3D G3DSA:3.50.30.10 386 510 2.2E-66 T 23-10-2018 VMUT_1318 d8a47ea388facd578953cdecf82f9f7b 893 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 6 879 0.0 T 23-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 VMUT_1318 d8a47ea388facd578953cdecf82f9f7b 893 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 451 462 - T 23-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 VMUT_1966 8d2be8b7590417d6147a28d06b5fca29 438 Gene3D G3DSA:3.40.50.1480 5 427 2.3E-173 T 23-10-2018 VMUT_1966 8d2be8b7590417d6147a28d06b5fca29 438 SUPERFAMILY SSF52283 2 438 1.87E-98 T 23-10-2018 VMUT_1966 8d2be8b7590417d6147a28d06b5fca29 438 SUPERFAMILY SSF51735 204 367 4.58E-64 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1966 8d2be8b7590417d6147a28d06b5fca29 438 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 226 242 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 VMUT_1966 8d2be8b7590417d6147a28d06b5fca29 438 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 204 365 5.4E-51 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 VMUT_1966 8d2be8b7590417d6147a28d06b5fca29 438 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 3 432 1.6E-74 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 VMUT_1966 8d2be8b7590417d6147a28d06b5fca29 438 Gene3D G3DSA:3.40.50.720 206 366 2.3E-173 T 23-10-2018 VMUT_1966 8d2be8b7590417d6147a28d06b5fca29 438 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 3 438 9.3E-195 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 VMUT_1966 8d2be8b7590417d6147a28d06b5fca29 438 PIRSF PIRSF001109 1 438 1.3E-190 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 VMUT_1966 8d2be8b7590417d6147a28d06b5fca29 438 SMART SM00997 204 366 3.6E-104 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 VMUT_1966 8d2be8b7590417d6147a28d06b5fca29 438 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 1 438 49.8 T 23-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 VMUT_1966 8d2be8b7590417d6147a28d06b5fca29 438 SMART SM00996 2 437 1.6E-149 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 VMUT_1966 8d2be8b7590417d6147a28d06b5fca29 438 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 74 88 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 VMUT_0609 cfa9e894a0b5366b060f48d5af10cfeb 280 Pfam PF01925 Sulfite exporter TauE/SafE 11 271 2.1E-28 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 VMUT_1876 68904a8730ce73624050d5e68284a290 392 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 298 2.4E-18 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VMUT_1876 68904a8730ce73624050d5e68284a290 392 SUPERFAMILY SSF51905 127 253 9.26E-27 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_1876 68904a8730ce73624050d5e68284a290 392 Gene3D G3DSA:3.50.50.60 127 255 2.9E-66 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_1876 68904a8730ce73624050d5e68284a290 392 SUPERFAMILY SSF51905 4 325 7.22E-23 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_1876 68904a8730ce73624050d5e68284a290 392 Gene3D G3DSA:3.50.50.60 7 309 2.9E-66 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_1528 05e38ec9ee9749da14dc93eccb1c745e 359 Pfam PF00696 Amino acid kinase family 1 263 4.9E-35 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 VMUT_1528 05e38ec9ee9749da14dc93eccb1c745e 359 SUPERFAMILY SSF53633 1 276 9.95E-48 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily VMUT_1528 05e38ec9ee9749da14dc93eccb1c745e 359 Gene3D G3DSA:3.40.1160.10 1 276 2.4E-53 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily VMUT_0784 7f037a7518bdc3d48734d8996cdc9d08 209 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 101 203 5.6E-29 T 23-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VMUT_0784 7f037a7518bdc3d48734d8996cdc9d08 209 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 170 177 - T 23-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VMUT_0784 7f037a7518bdc3d48734d8996cdc9d08 209 Gene3D G3DSA:1.10.287.990 28 92 1.5E-23 T 23-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VMUT_0784 7f037a7518bdc3d48734d8996cdc9d08 209 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 10 92 1.1E-28 T 23-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VMUT_0784 7f037a7518bdc3d48734d8996cdc9d08 209 SUPERFAMILY SSF46609 9 97 1.7E-28 T 23-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VMUT_0784 7f037a7518bdc3d48734d8996cdc9d08 209 SUPERFAMILY SSF54719 95 208 7.07E-36 T 23-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VMUT_0784 7f037a7518bdc3d48734d8996cdc9d08 209 Gene3D G3DSA:2.40.500.20 93 209 1.2E-39 T 23-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VMUT_0784 7f037a7518bdc3d48734d8996cdc9d08 209 PIRSF PIRSF000349 4 209 7.0E-67 T 23-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VMUT_0784 7f037a7518bdc3d48734d8996cdc9d08 209 PRINTS PR01703 Manganese superoxide dismutase signature 14 25 1.3E-15 T 23-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VMUT_0784 7f037a7518bdc3d48734d8996cdc9d08 209 PRINTS PR01703 Manganese superoxide dismutase signature 35 48 1.3E-15 T 23-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VMUT_0784 7f037a7518bdc3d48734d8996cdc9d08 209 PRINTS PR01703 Manganese superoxide dismutase signature 168 180 1.3E-15 T 23-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VMUT_0784 7f037a7518bdc3d48734d8996cdc9d08 209 PRINTS PR01703 Manganese superoxide dismutase signature 130 138 1.3E-15 T 23-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VMUT_0784 7f037a7518bdc3d48734d8996cdc9d08 209 PRINTS PR01703 Manganese superoxide dismutase signature 75 88 1.3E-15 T 23-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VMUT_1315 552a6b6190665f1cc95be2533db49313 364 Pfam PF00557 Metallopeptidase family M24 146 344 3.6E-55 T 23-10-2018 IPR000994 Peptidase M24 VMUT_1315 552a6b6190665f1cc95be2533db49313 364 SUPERFAMILY SSF53092 5 136 7.5E-14 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal VMUT_1315 552a6b6190665f1cc95be2533db49313 364 Gene3D G3DSA:3.40.350.10 4 137 2.2E-16 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal VMUT_1315 552a6b6190665f1cc95be2533db49313 364 Gene3D G3DSA:3.90.230.10 139 359 1.3E-68 T 23-10-2018 VMUT_1315 552a6b6190665f1cc95be2533db49313 364 Pfam PF01321 Creatinase/Prolidase N-terminal domain 6 136 1.6E-10 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 VMUT_1315 552a6b6190665f1cc95be2533db49313 364 SUPERFAMILY SSF55920 139 354 1.57E-63 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like VMUT_1315 552a6b6190665f1cc95be2533db49313 364 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 292 304 - T 23-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site VMUT_0874 6ffc3876186459cf75de7e6f3388d649 339 Gene3D G3DSA:3.60.15.10 9 202 2.1E-25 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_0874 6ffc3876186459cf75de7e6f3388d649 339 SUPERFAMILY SSF56281 12 321 1.55E-37 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_0874 6ffc3876186459cf75de7e6f3388d649 339 Pfam PF12706 Beta-lactamase superfamily domain 25 152 5.5E-7 T 23-10-2018 IPR001279 Metallo-beta-lactamase VMUT_0874 6ffc3876186459cf75de7e6f3388d649 339 SMART SM00849 8 157 6.4E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase VMUT_2209 3aa4297b6e8fa3a4ea51d39c9ecd9c72 251 SUPERFAMILY SSF102114 23 237 3.01E-34 T 23-10-2018 VMUT_2209 3aa4297b6e8fa3a4ea51d39c9ecd9c72 251 SMART SM00729 14 231 0.0068 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VMUT_2209 3aa4297b6e8fa3a4ea51d39c9ecd9c72 251 Pfam PF04055 Radical SAM superfamily 23 188 5.9E-21 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_2209 3aa4297b6e8fa3a4ea51d39c9ecd9c72 251 Gene3D G3DSA:3.20.20.70 21 246 3.7E-30 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_2063 6c18c767cc5656e4eff5cac47e1481f3 150 Gene3D G3DSA:2.40.50.140 31 150 6.2E-47 T 23-10-2018 VMUT_2063 6c18c767cc5656e4eff5cac47e1481f3 150 SUPERFAMILY SSF50249 26 148 1.68E-34 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold VMUT_2063 6c18c767cc5656e4eff5cac47e1481f3 150 Pfam PF00164 Ribosomal protein S12/S23 35 148 1.4E-42 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_2063 6c18c767cc5656e4eff5cac47e1481f3 150 Hamap MF_00403_A 30S ribosomal protein S12 [rpsL]. 4 150 41.087 T 23-10-2018 IPR022863 Ribosomal protein S12, archaea VMUT_2063 6c18c767cc5656e4eff5cac47e1481f3 150 PIRSF PIRSF002133 22 150 6.2E-32 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_2063 6c18c767cc5656e4eff5cac47e1481f3 150 TIGRFAM TIGR00982 uS12_E_A: ribosomal protein uS12 12 150 2.7E-70 T 23-10-2018 IPR005680 Ribosomal protein S23, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0127 5242a4dd4e1a7331eaf0747425806b48 414 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 16 128 6.6E-19 T 23-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VMUT_0127 5242a4dd4e1a7331eaf0747425806b48 414 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 250 408 7.0E-37 T 23-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VMUT_0127 5242a4dd4e1a7331eaf0747425806b48 414 Gene3D G3DSA:1.20.140.10 256 413 1.3E-35 T 23-10-2018 VMUT_0127 5242a4dd4e1a7331eaf0747425806b48 414 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 132 236 3.3E-13 T 23-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VMUT_0127 5242a4dd4e1a7331eaf0747425806b48 414 Gene3D G3DSA:2.40.110.10 132 255 3.8E-18 T 23-10-2018 VMUT_0127 5242a4dd4e1a7331eaf0747425806b48 414 SUPERFAMILY SSF47203 248 411 5.8E-40 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VMUT_0127 5242a4dd4e1a7331eaf0747425806b48 414 SUPERFAMILY SSF56645 8 261 2.23E-46 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VMUT_0127 5242a4dd4e1a7331eaf0747425806b48 414 Gene3D G3DSA:1.10.540.10 6 129 1.5E-24 T 23-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VMUT_0127 5242a4dd4e1a7331eaf0747425806b48 414 PIRSF PIRSF016578 39 203 0.0014 T 23-10-2018 VMUT_0127 5242a4dd4e1a7331eaf0747425806b48 414 PIRSF PIRSF016578 254 389 8.7E-11 T 23-10-2018 VMUT_0216 02045845084eaa83a05c288e0440a0c1 385 Hamap MF_00424 Peptide chain release factor subunit 1 [prf1]. 22 371 33.688 T 23-10-2018 IPR020918 Peptide chain release factor aRF1 GO:0003747|GO:0005737|GO:0006415 VMUT_0216 02045845084eaa83a05c288e0440a0c1 385 Gene3D G3DSA:3.30.1330.30 273 367 2.2E-10 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like VMUT_0216 02045845084eaa83a05c288e0440a0c1 385 SUPERFAMILY SSF55481 13 139 5.49E-42 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0216 02045845084eaa83a05c288e0440a0c1 385 TIGRFAM TIGR03676 aRF1/eRF1: peptide chain release factor 1, archaeal and eukaryotic forms 14 324 3.6E-114 T 23-10-2018 IPR004403 Peptide chain release factor eRF1/aRF1 GO:0003747|GO:0005737|GO:0006415 Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0216 02045845084eaa83a05c288e0440a0c1 385 Pfam PF03464 eRF1 domain 2 144 273 1.5E-31 T 23-10-2018 IPR005141 eRF1 domain 2 VMUT_0216 02045845084eaa83a05c288e0440a0c1 385 Pfam PF03465 eRF1 domain 3 276 366 5.5E-5 T 23-10-2018 IPR005142 eRF1 domain 3 VMUT_0216 02045845084eaa83a05c288e0440a0c1 385 SUPERFAMILY SSF53137 142 271 1.22E-34 T 23-10-2018 VMUT_0216 02045845084eaa83a05c288e0440a0c1 385 Gene3D G3DSA:3.30.420.60 141 272 2.2E-38 T 23-10-2018 VMUT_0216 02045845084eaa83a05c288e0440a0c1 385 SMART SM01194 7 139 8.3E-25 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like VMUT_0216 02045845084eaa83a05c288e0440a0c1 385 Gene3D G3DSA:3.30.960.10 9 140 5.4E-40 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0216 02045845084eaa83a05c288e0440a0c1 385 SUPERFAMILY SSF55315 273 367 6.02E-12 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like VMUT_1362 f74218fba82edcfcfbf9598853e2d406 312 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 6.5E-5 T 23-10-2018 VMUT_1362 f74218fba82edcfcfbf9598853e2d406 312 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 300 6.5E-5 T 23-10-2018 VMUT_1362 f74218fba82edcfcfbf9598853e2d406 312 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 159 1.9E-8 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VMUT_1362 f74218fba82edcfcfbf9598853e2d406 312 SUPERFAMILY SSF51905 3 206 2.33E-20 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_1362 f74218fba82edcfcfbf9598853e2d406 312 Gene3D G3DSA:3.50.50.60 99 159 6.6E-13 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_1362 f74218fba82edcfcfbf9598853e2d406 312 Gene3D G3DSA:3.50.50.60 6 98 6.6E-13 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0580 0143e2763334af9e05681964f671b01f 412 Pfam PF02163 Peptidase family M50 148 392 6.7E-19 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 VMUT_0580 0143e2763334af9e05681964f671b01f 412 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 190 202 2.2E-9 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 VMUT_0580 0143e2763334af9e05681964f671b01f 412 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 157 171 2.2E-9 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 VMUT_0580 0143e2763334af9e05681964f671b01f 412 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 134 153 2.2E-9 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 VMUT_0718 6efacb37241aeafe4c513a97c5f5e302 400 Pfam PF00534 Glycosyl transferases group 1 209 365 4.9E-44 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 VMUT_0718 6efacb37241aeafe4c513a97c5f5e302 400 Gene3D G3DSA:3.40.50.2000 187 367 2.9E-88 T 23-10-2018 VMUT_0718 6efacb37241aeafe4c513a97c5f5e302 400 SUPERFAMILY SSF53756 4 388 7.68E-101 T 23-10-2018 VMUT_0718 6efacb37241aeafe4c513a97c5f5e302 400 Gene3D G3DSA:3.40.50.2000 7 384 2.9E-88 T 23-10-2018 VMUT_0718 6efacb37241aeafe4c513a97c5f5e302 400 Pfam PF13439 Glycosyltransferase Family 4 17 190 5.8E-29 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 VMUT_0124 23609a3470cc2e8da0ea2b163c66afcc 503 SUPERFAMILY SSF53187 17 379 1.18E-24 T 23-10-2018 VMUT_0124 23609a3470cc2e8da0ea2b163c66afcc 503 Gene3D G3DSA:3.50.30.30 58 181 4.5E-31 T 23-10-2018 VMUT_0124 23609a3470cc2e8da0ea2b163c66afcc 503 Gene3D G3DSA:3.40.630.10 23 367 4.5E-31 T 23-10-2018 VMUT_0124 23609a3470cc2e8da0ea2b163c66afcc 503 Pfam PF04389 Peptidase family M28 191 373 2.9E-15 T 23-10-2018 IPR007484 Peptidase M28 VMUT_1523 f1b1392a07d082a7fddccf592ed433c2 327 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 326 38.369 T 23-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 VMUT_1523 f1b1392a07d082a7fddccf592ed433c2 327 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 325 8.0E-51 T 23-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 VMUT_1523 f1b1392a07d082a7fddccf592ed433c2 327 SUPERFAMILY SSF48179 183 324 4.25E-54 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VMUT_1523 f1b1392a07d082a7fddccf592ed433c2 327 Gene3D G3DSA:3.40.50.720 1 181 3.1E-72 T 23-10-2018 VMUT_1523 f1b1392a07d082a7fddccf592ed433c2 327 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 177 6.8E-66 T 23-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 VMUT_1523 f1b1392a07d082a7fddccf592ed433c2 327 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 16 325 5.7E-117 T 23-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 VMUT_1523 f1b1392a07d082a7fddccf592ed433c2 327 Gene3D G3DSA:1.10.3730.40 182 327 5.6E-54 T 23-10-2018 VMUT_1523 f1b1392a07d082a7fddccf592ed433c2 327 SUPERFAMILY SSF51735 3 182 1.35E-64 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1523 f1b1392a07d082a7fddccf592ed433c2 327 PIRSF PIRSF000116 204 326 4.8E-12 T 23-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 VMUT_1523 f1b1392a07d082a7fddccf592ed433c2 327 PIRSF PIRSF000116 3 208 4.6E-39 T 23-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 VMUT_0586 af5b73a35f70e0bf3383942c0f6a01ae 593 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 224 589 2.8E-99 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_0586 af5b73a35f70e0bf3383942c0f6a01ae 593 SUPERFAMILY SSF48310 214 589 8.63E-96 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_0586 af5b73a35f70e0bf3383942c0f6a01ae 593 SUPERFAMILY SSF56228 1 204 3.53E-64 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily VMUT_0586 af5b73a35f70e0bf3383942c0f6a01ae 593 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 203 4.1E-70 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_0586 af5b73a35f70e0bf3383942c0f6a01ae 593 Gene3D G3DSA:1.10.569.10 242 420 1.5E-95 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 VMUT_0586 af5b73a35f70e0bf3383942c0f6a01ae 593 Gene3D G3DSA:3.60.9.10 1 209 2.1E-73 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily VMUT_0586 af5b73a35f70e0bf3383942c0f6a01ae 593 SMART SM00790 4 209 2.8E-86 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_0586 af5b73a35f70e0bf3383942c0f6a01ae 593 Gene3D G3DSA:1.10.599.10 241 588 1.5E-95 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 VMUT_1303 11080980b87af2c65378e30f0cce4c11 700 Gene3D G3DSA:3.30.365.10 353 431 1.4E-30 T 23-10-2018 VMUT_1303 11080980b87af2c65378e30f0cce4c11 700 Gene3D G3DSA:3.90.1170.50 26 118 3.0E-92 T 23-10-2018 VMUT_1303 11080980b87af2c65378e30f0cce4c11 700 Gene3D G3DSA:3.30.365.10 12 267 3.0E-92 T 23-10-2018 VMUT_1303 11080980b87af2c65378e30f0cce4c11 700 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 134 631 6.4E-114 T 23-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 VMUT_1303 11080980b87af2c65378e30f0cce4c11 700 SMART SM01008 11 118 2.3E-26 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead VMUT_1303 11080980b87af2c65378e30f0cce4c11 700 SUPERFAMILY SSF54665 4 135 5.76E-29 T 23-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily VMUT_1303 11080980b87af2c65378e30f0cce4c11 700 Gene3D G3DSA:3.30.365.10 432 526 1.4E-30 T 23-10-2018 VMUT_1303 11080980b87af2c65378e30f0cce4c11 700 SUPERFAMILY SSF56003 110 697 2.36E-135 T 23-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 VMUT_1303 11080980b87af2c65378e30f0cce4c11 700 Gene3D G3DSA:3.30.365.10 548 691 4.2E-29 T 23-10-2018 VMUT_1303 11080980b87af2c65378e30f0cce4c11 700 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 12 118 3.1E-16 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead VMUT_1303 11080980b87af2c65378e30f0cce4c11 700 Gene3D G3DSA:3.30.365.10 119 344 3.0E-92 T 23-10-2018 VMUT_0689 39f0e515e9b4db82eece388a675c33ab 231 SMART SM00525 202 222 7.5E-5 T 23-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 VMUT_0689 39f0e515e9b4db82eece388a675c33ab 231 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 203 219 - T 23-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 VMUT_0689 39f0e515e9b4db82eece388a675c33ab 231 SUPERFAMILY SSF48150 27 223 2.98E-55 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 VMUT_0689 39f0e515e9b4db82eece388a675c33ab 231 SMART SM00478 43 201 9.8E-39 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 VMUT_0689 39f0e515e9b4db82eece388a675c33ab 231 Gene3D G3DSA:1.10.340.30 27 140 4.4E-29 T 23-10-2018 VMUT_0689 39f0e515e9b4db82eece388a675c33ab 231 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 39 179 1.2E-19 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 VMUT_0689 39f0e515e9b4db82eece388a675c33ab 231 Gene3D G3DSA:1.10.1670.10 141 225 4.7E-22 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 VMUT_0689 39f0e515e9b4db82eece388a675c33ab 231 PIRSF PIRSF001435 5 227 7.6E-56 T 23-10-2018 VMUT_0615 1c0a10b5ccf5853a1a1cb7d3b1d06563 433 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 8 433 4.8E-152 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 VMUT_0615 1c0a10b5ccf5853a1a1cb7d3b1d06563 433 Gene3D G3DSA:2.40.50.140 3 105 5.9E-24 T 23-10-2018 VMUT_0615 1c0a10b5ccf5853a1a1cb7d3b1d06563 433 PRINTS PR01042 Aspartyl-tRNA synthetase signature 348 364 4.2E-20 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_0615 1c0a10b5ccf5853a1a1cb7d3b1d06563 433 PRINTS PR01042 Aspartyl-tRNA synthetase signature 205 218 4.2E-20 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_0615 1c0a10b5ccf5853a1a1cb7d3b1d06563 433 PRINTS PR01042 Aspartyl-tRNA synthetase signature 388 402 4.2E-20 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_0615 1c0a10b5ccf5853a1a1cb7d3b1d06563 433 PRINTS PR01042 Aspartyl-tRNA synthetase signature 189 201 4.2E-20 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_0615 1c0a10b5ccf5853a1a1cb7d3b1d06563 433 SUPERFAMILY SSF50249 5 104 1.2E-23 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold VMUT_0615 1c0a10b5ccf5853a1a1cb7d3b1d06563 433 SUPERFAMILY SSF55681 118 428 6.57E-86 T 23-10-2018 VMUT_0615 1c0a10b5ccf5853a1a1cb7d3b1d06563 433 Gene3D G3DSA:3.30.930.10 109 433 4.4E-102 T 23-10-2018 VMUT_0615 1c0a10b5ccf5853a1a1cb7d3b1d06563 433 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 5 433 37.68 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 VMUT_0615 1c0a10b5ccf5853a1a1cb7d3b1d06563 433 Pfam PF00152 tRNA synthetases class II (D, K and N) 120 427 5.9E-82 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_0615 1c0a10b5ccf5853a1a1cb7d3b1d06563 433 Pfam PF01336 OB-fold nucleic acid binding domain 22 101 2.6E-9 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 VMUT_0893 b40281b1862b12a6919ff3bdf69d9801 356 SUPERFAMILY SSF53448 6 239 3.49E-31 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0893 b40281b1862b12a6919ff3bdf69d9801 356 Gene3D G3DSA:3.90.550.10 4 234 1.3E-39 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0893 b40281b1862b12a6919ff3bdf69d9801 356 Pfam PF00535 Glycosyl transferase family 2 7 178 6.6E-26 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VMUT_0888 528cebd9210d2e44adab48ae6eaee904 406 Gene3D G3DSA:3.20.110.20 4 336 6.7E-23 T 23-10-2018 VMUT_0888 528cebd9210d2e44adab48ae6eaee904 406 SUPERFAMILY SSF88713 4 349 3.71E-53 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 VMUT_0888 528cebd9210d2e44adab48ae6eaee904 406 Pfam PF03065 Glycosyl hydrolase family 57 12 324 1.7E-52 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 VMUT_0705 49585f603244d0baa38d5a4d0fed22e2 530 SMART SM00491 367 503 0.0012 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 VMUT_0705 49585f603244d0baa38d5a4d0fed22e2 530 Pfam PF13307 Helicase C-terminal domain 358 512 1.0E-20 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 VMUT_0705 49585f603244d0baa38d5a4d0fed22e2 530 Pfam PF06733 DEAD_2 122 190 8.2E-5 T 23-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 VMUT_0705 49585f603244d0baa38d5a4d0fed22e2 530 SUPERFAMILY SSF52540 10 489 8.76E-16 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0705 49585f603244d0baa38d5a4d0fed22e2 530 Gene3D G3DSA:3.40.50.300 3 184 2.9E-18 T 23-10-2018 VMUT_0705 49585f603244d0baa38d5a4d0fed22e2 530 Gene3D G3DSA:3.40.50.300 316 528 9.5E-23 T 23-10-2018 VMUT_0262 0e1c73a410e433a62008f183e9666e52 372 Pfam PF00483 Nucleotidyl transferase 7 236 1.5E-41 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 VMUT_0262 0e1c73a410e433a62008f183e9666e52 372 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 264 296 5.8E-7 T 23-10-2018 IPR001451 Hexapeptide repeat VMUT_0262 0e1c73a410e433a62008f183e9666e52 372 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 316 349 3.5E-6 T 23-10-2018 IPR001451 Hexapeptide repeat VMUT_0262 0e1c73a410e433a62008f183e9666e52 372 Gene3D G3DSA:3.90.550.10 1 252 1.0E-67 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0262 0e1c73a410e433a62008f183e9666e52 372 SUPERFAMILY SSF53448 6 304 1.32E-68 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0262 0e1c73a410e433a62008f183e9666e52 372 Gene3D G3DSA:2.160.10.10 253 371 8.3E-20 T 23-10-2018 VMUT_0262 0e1c73a410e433a62008f183e9666e52 372 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 318 346 - T 23-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 VMUT_1589 b6dd945f1ff2ae26b7f3a195c1e4b41e 364 Gene3D G3DSA:3.40.50.300 5 212 1.1E-60 T 23-10-2018 VMUT_1589 b6dd945f1ff2ae26b7f3a195c1e4b41e 364 SUPERFAMILY SSF52540 71 345 3.81E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1589 b6dd945f1ff2ae26b7f3a195c1e4b41e 364 Gene3D G3DSA:3.40.50.300 213 361 4.1E-42 T 23-10-2018 VMUT_1589 b6dd945f1ff2ae26b7f3a195c1e4b41e 364 SMART SM00487 20 214 1.3E-50 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain VMUT_1589 b6dd945f1ff2ae26b7f3a195c1e4b41e 364 Pfam PF00271 Helicase conserved C-terminal domain 231 328 5.9E-27 T 23-10-2018 IPR001650 Helicase, C-terminal VMUT_1589 b6dd945f1ff2ae26b7f3a195c1e4b41e 364 SMART SM00490 248 329 2.7E-26 T 23-10-2018 IPR001650 Helicase, C-terminal VMUT_1589 b6dd945f1ff2ae26b7f3a195c1e4b41e 364 Pfam PF00270 DEAD/DEAH box helicase 25 187 8.4E-42 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 VMUT_2054 7a6ab2693ed8cb71fa25fbb5aacc3da9 209 SUPERFAMILY SSF50182 133 194 7.19E-10 T 23-10-2018 IPR010920 LSM domain superfamily VMUT_2054 7a6ab2693ed8cb71fa25fbb5aacc3da9 209 Gene3D G3DSA:2.30.30.60 148 195 1.3E-9 T 23-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily VMUT_2054 7a6ab2693ed8cb71fa25fbb5aacc3da9 209 Pfam PF00924 Mechanosensitive ion channel 93 194 7.7E-19 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 VMUT_1496 994002799a6af02938e8a43f001dfbb9 344 SUPERFAMILY SSF160980 7 315 9.02E-23 T 23-10-2018 VMUT_1496 994002799a6af02938e8a43f001dfbb9 344 Gene3D G3DSA:3.40.50.10640 3 166 4.5E-15 T 23-10-2018 VMUT_1496 994002799a6af02938e8a43f001dfbb9 344 Pfam PF09455 CRISPR-associated (Cas) DxTHG family 10 304 1.3E-13 T 23-10-2018 IPR019016 CRISPR-associated DxTHG protein VMUT_1496 994002799a6af02938e8a43f001dfbb9 344 Gene3D G3DSA:1.10.3740.10 103 314 4.5E-15 T 23-10-2018 IPR027419 CRISPR-associated protein Csx1, C-terminal VMUT_1496 994002799a6af02938e8a43f001dfbb9 344 TIGRFAM TIGR02549 CRISPR_DxTHG: CRISPR-associated DxTHG motif protein 15 33 1.7E-8 T 23-10-2018 IPR013383 CRISPR-associated protein DxTHG, conserved site VMUT_0680 4a1f0f983337421a738bae28c27a2d50 402 SUPERFAMILY SSF56645 6 243 1.31E-66 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VMUT_0680 4a1f0f983337421a738bae28c27a2d50 402 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 131 224 1.4E-24 T 23-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VMUT_0680 4a1f0f983337421a738bae28c27a2d50 402 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 240 394 2.8E-44 T 23-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VMUT_0680 4a1f0f983337421a738bae28c27a2d50 402 Gene3D G3DSA:2.40.110.10 130 242 3.0E-35 T 23-10-2018 VMUT_0680 4a1f0f983337421a738bae28c27a2d50 402 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 13 125 1.1E-27 T 23-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VMUT_0680 4a1f0f983337421a738bae28c27a2d50 402 SUPERFAMILY SSF47203 239 398 1.05E-53 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VMUT_0680 4a1f0f983337421a738bae28c27a2d50 402 PIRSF PIRSF016578 19 114 210.0 T 23-10-2018 VMUT_0680 4a1f0f983337421a738bae28c27a2d50 402 PIRSF PIRSF016578 146 385 8.2E-15 T 23-10-2018 VMUT_0680 4a1f0f983337421a738bae28c27a2d50 402 Gene3D G3DSA:1.20.140.10 243 400 1.5E-52 T 23-10-2018 VMUT_0680 4a1f0f983337421a738bae28c27a2d50 402 Gene3D G3DSA:1.10.540.10 3 126 1.5E-31 T 23-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VMUT_0680 4a1f0f983337421a738bae28c27a2d50 402 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 354 373 - T 23-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 VMUT_0816 f192006ba72f51f082956291224ab405 516 Gene3D G3DSA:1.20.1440.230 417 514 9.0E-30 T 23-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_0816 f192006ba72f51f082956291224ab405 516 Gene3D G3DSA:3.10.20.600 330 415 3.8E-13 T 23-10-2018 VMUT_0816 f192006ba72f51f082956291224ab405 516 SMART SM00928 419 464 5.9E-19 T 23-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_0816 f192006ba72f51f082956291224ab405 516 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 421 504 2.1E-27 T 23-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_0816 f192006ba72f51f082956291224ab405 516 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 432 443 - T 23-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_0816 f192006ba72f51f082956291224ab405 516 SUPERFAMILY SSF142019 122 323 1.96E-44 T 23-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_0816 f192006ba72f51f082956291224ab405 516 Gene3D G3DSA:3.40.50.11540 159 326 1.2E-42 T 23-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_0816 f192006ba72f51f082956291224ab405 516 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 158 318 2.1E-28 T 23-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_0816 f192006ba72f51f082956291224ab405 516 Gene3D G3DSA:3.40.30.10 51 126 5.1E-8 T 23-10-2018 VMUT_0816 f192006ba72f51f082956291224ab405 516 SUPERFAMILY SSF142984 334 413 6.54E-12 T 23-10-2018 VMUT_0816 f192006ba72f51f082956291224ab405 516 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 18 106 2.9E-9 T 23-10-2018 VMUT_0816 f192006ba72f51f082956291224ab405 516 SUPERFAMILY SSF140490 415 508 1.7E-30 T 23-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_0816 f192006ba72f51f082956291224ab405 516 SUPERFAMILY SSF52833 20 106 7.38E-13 T 23-10-2018 IPR036249 Thioredoxin-like superfamily VMUT_0681 3575c5a30068e733c9401502edbf0300 469 Gene3D G3DSA:2.40.110.10 138 263 6.5E-46 T 23-10-2018 VMUT_0681 3575c5a30068e733c9401502edbf0300 469 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 269 464 6.2E-51 T 23-10-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal VMUT_0681 3575c5a30068e733c9401502edbf0300 469 PIRSF PIRSF000331 1 468 2.3E-135 T 23-10-2018 IPR004925 HpaB/PvcC/4-BUDH VMUT_0681 3575c5a30068e733c9401502edbf0300 469 SUPERFAMILY SSF47203 253 464 1.56E-53 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VMUT_0681 3575c5a30068e733c9401502edbf0300 469 Gene3D G3DSA:1.10.3140.10 1 136 2.1E-22 T 23-10-2018 VMUT_0681 3575c5a30068e733c9401502edbf0300 469 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 7 262 1.3E-79 T 23-10-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal VMUT_0681 3575c5a30068e733c9401502edbf0300 469 Gene3D G3DSA:1.20.140.10 266 466 2.1E-54 T 23-10-2018 VMUT_0681 3575c5a30068e733c9401502edbf0300 469 SUPERFAMILY SSF56645 1 262 3.27E-65 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VMUT_2013 401a26d61dad1b4818c272fb7a17963f 274 Pfam PF00892 EamA-like transporter family 139 269 5.5E-17 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VMUT_2013 401a26d61dad1b4818c272fb7a17963f 274 Pfam PF00892 EamA-like transporter family 6 131 4.2E-17 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VMUT_2013 401a26d61dad1b4818c272fb7a17963f 274 SUPERFAMILY SSF103481 40 131 2.88E-11 T 23-10-2018 VMUT_2013 401a26d61dad1b4818c272fb7a17963f 274 SUPERFAMILY SSF103481 176 272 4.58E-9 T 23-10-2018 VMUT_2198 859785108cf648c8fb9a811512fb56e8 350 SMART SM01004 16 343 1.1E-224 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 VMUT_2198 859785108cf648c8fb9a811512fb56e8 350 Pfam PF00490 Delta-aminolevulinic acid dehydratase 19 340 2.5E-147 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 VMUT_2198 859785108cf648c8fb9a811512fb56e8 350 PIRSF PIRSF001415 9 345 1.1E-152 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 VMUT_2198 859785108cf648c8fb9a811512fb56e8 350 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 261 277 1.1E-59 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 VMUT_2198 859785108cf648c8fb9a811512fb56e8 350 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 171 190 1.1E-59 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 VMUT_2198 859785108cf648c8fb9a811512fb56e8 350 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 287 302 1.1E-59 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 VMUT_2198 859785108cf648c8fb9a811512fb56e8 350 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 317 336 1.1E-59 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 VMUT_2198 859785108cf648c8fb9a811512fb56e8 350 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 136 150 1.1E-59 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 VMUT_2198 859785108cf648c8fb9a811512fb56e8 350 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 209 228 1.1E-59 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 VMUT_2198 859785108cf648c8fb9a811512fb56e8 350 Gene3D G3DSA:3.20.20.70 13 348 4.6E-152 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_2198 859785108cf648c8fb9a811512fb56e8 350 SUPERFAMILY SSF51569 10 345 1.61E-138 T 23-10-2018 VMUT_1978 503a0ca23a5f4ba8f8ad00a817bd12b3 54 ProSitePatterns PS00527 Ribosomal protein S14 signature. 21 42 - T 23-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1978 503a0ca23a5f4ba8f8ad00a817bd12b3 54 SUPERFAMILY SSF57716 6 51 4.42E-5 T 23-10-2018 VMUT_1978 503a0ca23a5f4ba8f8ad00a817bd12b3 54 Hamap MF_01364_A 30S ribosomal protein S14 type Z [rpsZ]. 2 54 17.017 T 23-10-2018 IPR023676 Ribosomal protein S14, type Z, archaeal GO:0003723|GO:0003735|GO:0006412|GO:0015935 VMUT_1978 503a0ca23a5f4ba8f8ad00a817bd12b3 54 Pfam PF00253 Ribosomal protein S14p/S29e 6 53 4.2E-11 T 23-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_1978 503a0ca23a5f4ba8f8ad00a817bd12b3 54 Gene3D G3DSA:4.10.830.10 1 54 1.7E-20 T 23-10-2018 VMUT_1443 baaf0757f0c503c94107aba12e2236d8 278 SUPERFAMILY SSF103481 177 275 2.48E-13 T 23-10-2018 VMUT_1443 baaf0757f0c503c94107aba12e2236d8 278 Pfam PF00892 EamA-like transporter family 137 273 1.2E-14 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VMUT_1443 baaf0757f0c503c94107aba12e2236d8 278 SUPERFAMILY SSF103481 38 126 2.75E-6 T 23-10-2018 VMUT_1358 87417051e71f1f83657cf86996b3732b 362 TIGRFAM TIGR03699 menaquin_MqnC: dehypoxanthine futalosine cyclase 17 358 2.1E-137 T 23-10-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 VMUT_1358 87417051e71f1f83657cf86996b3732b 362 SUPERFAMILY SSF102114 29 341 5.76E-50 T 23-10-2018 VMUT_1358 87417051e71f1f83657cf86996b3732b 362 PIRSF PIRSF004762 3 362 4.8E-107 T 23-10-2018 VMUT_1358 87417051e71f1f83657cf86996b3732b 362 Gene3D G3DSA:3.20.20.70 4 325 1.7E-56 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_1358 87417051e71f1f83657cf86996b3732b 362 Pfam PF04055 Radical SAM superfamily 60 225 1.4E-15 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_1358 87417051e71f1f83657cf86996b3732b 362 Hamap MF_00992 Cyclic dehypoxanthine futalosine synthase [mqnC]. 15 361 47.038 T 23-10-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 VMUT_1358 87417051e71f1f83657cf86996b3732b 362 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 50 357 8.6E-106 T 23-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 VMUT_0721 65ffc60061a6a3bf3a70b2cb9716e868 346 Hamap MF_00497_A Glycerol-1-phosphate dehydrogenase [NAD(P)+] [egsA]. 1 346 39.668 T 23-10-2018 IPR023002 Glycerol-1-phosphate dehydrogenase, archaea GO:0050492|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 VMUT_0721 65ffc60061a6a3bf3a70b2cb9716e868 346 PIRSF PIRSF000112 1 341 1.3E-61 T 23-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 VMUT_0721 65ffc60061a6a3bf3a70b2cb9716e868 346 SUPERFAMILY SSF56796 2 328 1.3E-59 T 23-10-2018 VMUT_0721 65ffc60061a6a3bf3a70b2cb9716e868 346 Pfam PF13685 Iron-containing alcohol dehydrogenase 10 269 1.3E-54 T 23-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 VMUT_0721 65ffc60061a6a3bf3a70b2cb9716e868 346 Gene3D G3DSA:1.20.1090.10 153 345 1.1E-56 T 23-10-2018 VMUT_0721 65ffc60061a6a3bf3a70b2cb9716e868 346 Gene3D G3DSA:3.40.50.1970 1 152 5.3E-25 T 23-10-2018 VMUT_0136 d1595a13fd06c21021280965b3eb3771 429 Pfam PF00152 tRNA synthetases class II (D, K and N) 109 422 3.6E-91 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_0136 d1595a13fd06c21021280965b3eb3771 429 SUPERFAMILY SSF55681 108 423 1.51E-91 T 23-10-2018 VMUT_0136 d1595a13fd06c21021280965b3eb3771 429 Gene3D G3DSA:3.30.930.10 100 429 5.3E-114 T 23-10-2018 VMUT_0136 d1595a13fd06c21021280965b3eb3771 429 Pfam PF01336 OB-fold nucleic acid binding domain 15 89 4.9E-10 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 VMUT_0136 d1595a13fd06c21021280965b3eb3771 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 344 360 4.5E-16 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_0136 d1595a13fd06c21021280965b3eb3771 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 180 192 4.5E-16 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_0136 d1595a13fd06c21021280965b3eb3771 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 196 209 4.5E-16 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_0136 d1595a13fd06c21021280965b3eb3771 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 384 398 4.5E-16 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_0136 d1595a13fd06c21021280965b3eb3771 429 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 10 428 7.4E-129 T 23-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 VMUT_0136 d1595a13fd06c21021280965b3eb3771 429 SUPERFAMILY SSF50249 3 91 8.78E-20 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold VMUT_0136 d1595a13fd06c21021280965b3eb3771 429 Gene3D G3DSA:2.40.50.140 1 93 5.7E-21 T 23-10-2018 VMUT_1750 9c6e41a8095305381e5bc508f5386913 144 Hamap MF_01112 UPF0201 protein . 1 133 27.274 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 VMUT_1750 9c6e41a8095305381e5bc508f5386913 144 Pfam PF01877 RNA binding 4 114 1.1E-16 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 VMUT_1750 9c6e41a8095305381e5bc508f5386913 144 SUPERFAMILY SSF55282 4 142 3.3E-40 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1750 9c6e41a8095305381e5bc508f5386913 144 Gene3D G3DSA:3.30.1440.10 2 135 7.7E-40 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0933 48191d81cffecf1a771ba4964e2ec8f2 192 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 3 188 39.446 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like VMUT_0933 48191d81cffecf1a771ba4964e2ec8f2 192 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 4 186 8.7E-79 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like VMUT_0933 48191d81cffecf1a771ba4964e2ec8f2 192 SUPERFAMILY SSF52507 3 188 2.35E-63 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 VMUT_0933 48191d81cffecf1a771ba4964e2ec8f2 192 Gene3D G3DSA:3.40.50.1950 3 192 1.8E-81 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 VMUT_0933 48191d81cffecf1a771ba4964e2ec8f2 192 Pfam PF02441 Flavoprotein 4 167 5.9E-30 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 VMUT_1437 46b9e3e6541c77d536f6a267f894fa00 380 Pfam PF01171 PP-loop family 27 184 7.4E-7 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 VMUT_1437 46b9e3e6541c77d536f6a267f894fa00 380 Pfam PF00958 GMP synthase C terminal domain 322 379 1.2E-14 T 23-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 VMUT_1437 46b9e3e6541c77d536f6a267f894fa00 380 SUPERFAMILY SSF54810 197 316 2.09E-11 T 23-10-2018 VMUT_1437 46b9e3e6541c77d536f6a267f894fa00 380 Gene3D G3DSA:3.30.300.10 318 380 5.5E-13 T 23-10-2018 VMUT_1437 46b9e3e6541c77d536f6a267f894fa00 380 Gene3D G3DSA:3.30.300.10 198 317 1.6E-13 T 23-10-2018 VMUT_1437 46b9e3e6541c77d536f6a267f894fa00 380 Gene3D G3DSA:3.40.50.620 9 197 4.5E-56 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_1437 46b9e3e6541c77d536f6a267f894fa00 380 SUPERFAMILY SSF54810 322 380 6.02E-15 T 23-10-2018 VMUT_1437 46b9e3e6541c77d536f6a267f894fa00 380 SUPERFAMILY SSF52402 15 228 4.19E-38 T 23-10-2018 VMUT_0206 dfa81af559e76cc335ec42e919753927 157 Pfam PF01883 Iron-sulfur cluster assembly protein 34 106 3.5E-17 T 23-10-2018 IPR002744 MIP18 family-like VMUT_0206 dfa81af559e76cc335ec42e919753927 157 Gene3D G3DSA:3.30.300.130 25 127 2.8E-31 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily VMUT_0206 dfa81af559e76cc335ec42e919753927 157 SUPERFAMILY SSF117916 32 125 1.96E-25 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily VMUT_0726 48716e5bee47ce83f6fa73774548a537 484 Gene3D G3DSA:3.40.50.261 150 318 6.1E-53 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VMUT_0726 48716e5bee47ce83f6fa73774548a537 484 SMART SM00881 27 121 6.7E-37 T 23-10-2018 IPR003781 CoA-binding GO:0048037 VMUT_0726 48716e5bee47ce83f6fa73774548a537 484 SUPERFAMILY SSF51735 20 159 5.07E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0726 48716e5bee47ce83f6fa73774548a537 484 SUPERFAMILY SSF52210 321 475 2.62E-30 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VMUT_0726 48716e5bee47ce83f6fa73774548a537 484 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 175 315 5.2E-46 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain VMUT_0726 48716e5bee47ce83f6fa73774548a537 484 SUPERFAMILY SSF52210 151 318 8.24E-41 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VMUT_0726 48716e5bee47ce83f6fa73774548a537 484 Gene3D G3DSA:3.40.50.261 319 482 7.7E-43 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VMUT_0726 48716e5bee47ce83f6fa73774548a537 484 Pfam PF13380 CoA binding domain 31 154 1.2E-21 T 23-10-2018 IPR003781 CoA-binding GO:0048037 VMUT_0726 48716e5bee47ce83f6fa73774548a537 484 Gene3D G3DSA:3.40.50.720 23 149 2.6E-42 T 23-10-2018 VMUT_1156 165a78b27505ceeb936120867d3919bb 553 Gene3D G3DSA:2.30.40.10 6 513 3.1E-97 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VMUT_1156 165a78b27505ceeb936120867d3919bb 553 Gene3D G3DSA:3.20.20.140 56 499 3.1E-97 T 23-10-2018 VMUT_1156 165a78b27505ceeb936120867d3919bb 553 SUPERFAMILY SSF51556 55 493 4.21E-24 T 23-10-2018 IPR032466 Metal-dependent hydrolase VMUT_1156 165a78b27505ceeb936120867d3919bb 553 SUPERFAMILY SSF51338 28 550 3.65E-7 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VMUT_1156 165a78b27505ceeb936120867d3919bb 553 Gene3D G3DSA:3.10.310.70 75 192 3.1E-97 T 23-10-2018 VMUT_1156 165a78b27505ceeb936120867d3919bb 553 Pfam PF07969 Amidohydrolase family 44 548 2.2E-57 T 23-10-2018 IPR013108 Amidohydrolase 3 VMUT_2203 055dd11e87a2de88496e21192289ab45 739 SUPERFAMILY SSF50447 262 378 8.84E-32 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VMUT_2203 055dd11e87a2de88496e21192289ab45 739 SUPERFAMILY SSF54980 393 469 2.59E-19 T 23-10-2018 IPR035647 EF-G domain III/V-like VMUT_2203 055dd11e87a2de88496e21192289ab45 739 SUPERFAMILY SSF54211 469 630 1.85E-50 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VMUT_2203 055dd11e87a2de88496e21192289ab45 739 SMART SM00838 628 715 3.3E-36 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like VMUT_2203 055dd11e87a2de88496e21192289ab45 739 SUPERFAMILY SSF54980 631 722 1.49E-21 T 23-10-2018 IPR035647 EF-G domain III/V-like VMUT_2203 055dd11e87a2de88496e21192289ab45 739 Hamap MF_00054_A Elongation factor G [fusA]. 4 732 40.842 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 VMUT_2203 055dd11e87a2de88496e21192289ab45 739 Gene3D G3DSA:3.40.50.300 9 227 3.2E-67 T 23-10-2018 VMUT_2203 055dd11e87a2de88496e21192289ab45 739 TIGRFAM TIGR00490 aEF-2: translation elongation factor aEF-2 8 727 9.1E-264 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 VMUT_2203 055dd11e87a2de88496e21192289ab45 739 PRINTS PR00315 GTP-binding elongation factor signature 109 120 9.9E-12 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VMUT_2203 055dd11e87a2de88496e21192289ab45 739 PRINTS PR00315 GTP-binding elongation factor signature 25 38 9.9E-12 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VMUT_2203 055dd11e87a2de88496e21192289ab45 739 PRINTS PR00315 GTP-binding elongation factor signature 93 103 9.9E-12 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VMUT_2203 055dd11e87a2de88496e21192289ab45 739 PRINTS PR00315 GTP-binding elongation factor signature 145 154 9.9E-12 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VMUT_2203 055dd11e87a2de88496e21192289ab45 739 Gene3D G3DSA:3.30.70.240 472 725 1.3E-90 T 23-10-2018 VMUT_2203 055dd11e87a2de88496e21192289ab45 739 Gene3D G3DSA:3.30.230.10 478 729 1.3E-90 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup VMUT_2203 055dd11e87a2de88496e21192289ab45 739 Pfam PF00679 Elongation factor G C-terminus 629 711 1.3E-22 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like VMUT_2203 055dd11e87a2de88496e21192289ab45 739 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 25 156 4.2E-18 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 VMUT_2203 055dd11e87a2de88496e21192289ab45 739 Pfam PF03144 Elongation factor Tu domain 2 308 374 1.2E-15 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 VMUT_2203 055dd11e87a2de88496e21192289ab45 739 SMART SM00889 511 626 1.5E-23 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 VMUT_2203 055dd11e87a2de88496e21192289ab45 739 Gene3D G3DSA:3.30.70.870 393 467 5.3E-23 T 23-10-2018 VMUT_2203 055dd11e87a2de88496e21192289ab45 739 Gene3D G3DSA:2.40.30.10 261 392 5.8E-27 T 23-10-2018 VMUT_2203 055dd11e87a2de88496e21192289ab45 739 Pfam PF00009 Elongation factor Tu GTP binding domain 22 259 7.0E-59 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VMUT_2203 055dd11e87a2de88496e21192289ab45 739 Pfam PF14492 Elongation Factor G, domain II 392 465 3.6E-23 T 23-10-2018 VMUT_2203 055dd11e87a2de88496e21192289ab45 739 Pfam PF03764 Elongation factor G, domain IV 517 625 8.9E-29 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 VMUT_2203 055dd11e87a2de88496e21192289ab45 739 SUPERFAMILY SSF52540 10 256 1.3E-64 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1975 1276628381eb63464ceaf27a727321e8 476 Pfam PF06195 Protein of unknown function (DUF996) 38 178 3.2E-8 T 23-10-2018 IPR010397 Protein of unknown function DUF996 VMUT_1815 1515327a6f5664cd5492a20a65071ab0 666 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 92 117 2.4E-16 T 23-10-2018 VMUT_1815 1515327a6f5664cd5492a20a65071ab0 666 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 261 282 2.4E-16 T 23-10-2018 VMUT_1815 1515327a6f5664cd5492a20a65071ab0 666 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 283 309 2.4E-16 T 23-10-2018 VMUT_1815 1515327a6f5664cd5492a20a65071ab0 666 Pfam PF00361 Proton-conducting membrane transporter 187 466 2.9E-25 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_0004 91bf8cd7ed5bfd6b88b5d8e4817d4b2d 407 SUPERFAMILY SSF53383 22 404 2.37E-115 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VMUT_0004 91bf8cd7ed5bfd6b88b5d8e4817d4b2d 407 Pfam PF00155 Aminotransferase class I and II 37 398 2.7E-78 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VMUT_0004 91bf8cd7ed5bfd6b88b5d8e4817d4b2d 407 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 236 260 3.4E-11 T 23-10-2018 VMUT_0004 91bf8cd7ed5bfd6b88b5d8e4817d4b2d 407 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 169 193 3.4E-11 T 23-10-2018 VMUT_0004 91bf8cd7ed5bfd6b88b5d8e4817d4b2d 407 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 120 141 3.4E-11 T 23-10-2018 VMUT_0004 91bf8cd7ed5bfd6b88b5d8e4817d4b2d 407 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 205 228 3.4E-11 T 23-10-2018 VMUT_0004 91bf8cd7ed5bfd6b88b5d8e4817d4b2d 407 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 242 255 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 VMUT_0004 91bf8cd7ed5bfd6b88b5d8e4817d4b2d 407 Gene3D G3DSA:3.40.640.10 68 292 4.9E-126 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VMUT_0004 91bf8cd7ed5bfd6b88b5d8e4817d4b2d 407 Gene3D G3DSA:3.90.1150.10 32 398 4.9E-126 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VMUT_2058 5f1c201564f191c0d3179cd63d501804 1141 Pfam PF04567 RNA polymerase Rpb2, domain 5 621 661 1.1E-8 T 23-10-2018 IPR007647 RNA polymerase Rpb2, domain 5 GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_2058 5f1c201564f191c0d3179cd63d501804 1141 Pfam PF04561 RNA polymerase Rpb2, domain 2 206 371 1.3E-31 T 23-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_2058 5f1c201564f191c0d3179cd63d501804 1141 Gene3D G3DSA:3.90.1110.10 198 361 4.1E-49 T 23-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_2058 5f1c201564f191c0d3179cd63d501804 1141 Pfam PF04565 RNA polymerase Rpb2, domain 3 439 503 2.2E-27 T 23-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_2058 5f1c201564f191c0d3179cd63d501804 1141 SUPERFAMILY SSF64484 36 1133 0.0 T 23-10-2018 VMUT_2058 5f1c201564f191c0d3179cd63d501804 1141 TIGRFAM TIGR03670 rpoB_arch: DNA-directed RNA polymerase subunit B 537 1134 5.8E-300 T 23-10-2018 IPR019969 DNA-directed RNA polymerase subunit B (Rpo2) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_2058 5f1c201564f191c0d3179cd63d501804 1141 ProSitePatterns PS01166 RNA polymerases beta chain signature. 892 904 - T 23-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_2058 5f1c201564f191c0d3179cd63d501804 1141 Gene3D G3DSA:3.90.1800.10 1026 1134 4.3E-42 T 23-10-2018 VMUT_2058 5f1c201564f191c0d3179cd63d501804 1141 Pfam PF00562 RNA polymerase Rpb2, domain 6 668 1039 4.9E-131 T 23-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_2058 5f1c201564f191c0d3179cd63d501804 1141 Gene3D G3DSA:2.40.50.150 699 888 2.6E-145 T 23-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_2058 5f1c201564f191c0d3179cd63d501804 1141 Gene3D G3DSA:2.40.270.10 669 1025 2.6E-145 T 23-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_2058 5f1c201564f191c0d3179cd63d501804 1141 Pfam PF04566 RNA polymerase Rpb2, domain 4 537 600 1.4E-20 T 23-10-2018 IPR007646 RNA polymerase Rpb2, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_2058 5f1c201564f191c0d3179cd63d501804 1141 Gene3D G3DSA:3.90.1070.20 506 588 1.7E-26 T 23-10-2018 VMUT_2058 5f1c201564f191c0d3179cd63d501804 1141 Pfam PF04563 RNA polymerase beta subunit 49 418 2.9E-57 T 23-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_2058 5f1c201564f191c0d3179cd63d501804 1141 Gene3D G3DSA:3.90.1100.10 42 197 9.7E-20 T 23-10-2018 VMUT_2058 5f1c201564f191c0d3179cd63d501804 1141 Pfam PF04560 RNA polymerase Rpb2, domain 7 1041 1131 7.3E-30 T 23-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_1960 005f1a1b47a27f4faa4428701b071af9 199 Pfam PF09339 IclR helix-turn-helix domain 53 83 5.5E-7 T 23-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VMUT_1960 005f1a1b47a27f4faa4428701b071af9 199 Gene3D G3DSA:1.10.10.10 38 101 1.4E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_1960 005f1a1b47a27f4faa4428701b071af9 199 SUPERFAMILY SSF46785 52 93 1.12E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0309 8795eb17aba3b1a4ecdefe46075da7e5 162 SUPERFAMILY SSF52833 1 154 5.61E-47 T 23-10-2018 IPR036249 Thioredoxin-like superfamily VMUT_0309 8795eb17aba3b1a4ecdefe46075da7e5 162 Gene3D G3DSA:3.40.30.10 1 155 2.9E-49 T 23-10-2018 VMUT_0309 8795eb17aba3b1a4ecdefe46075da7e5 162 Pfam PF00578 AhpC/TSA family 4 131 1.0E-35 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 VMUT_0309 8795eb17aba3b1a4ecdefe46075da7e5 162 PIRSF PIRSF000239 1 159 5.3E-29 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 VMUT_0096 7723022838c7f4e0eb91ee5575c176f1 606 Pfam PF04675 DNA ligase N terminus 9 192 3.2E-38 T 23-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 VMUT_0096 7723022838c7f4e0eb91ee5575c176f1 606 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 63 593 5.9E-170 T 23-10-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 VMUT_0096 7723022838c7f4e0eb91ee5575c176f1 606 SUPERFAMILY SSF50249 451 595 6.28E-45 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold VMUT_0096 7723022838c7f4e0eb91ee5575c176f1 606 SUPERFAMILY SSF56091 237 442 8.87E-53 T 23-10-2018 VMUT_0096 7723022838c7f4e0eb91ee5575c176f1 606 SUPERFAMILY SSF117018 3 248 3.79E-65 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 VMUT_0096 7723022838c7f4e0eb91ee5575c176f1 606 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 264 272 - T 23-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 VMUT_0096 7723022838c7f4e0eb91ee5575c176f1 606 Gene3D G3DSA:1.10.3260.10 2 237 1.3E-73 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 VMUT_0096 7723022838c7f4e0eb91ee5575c176f1 606 Gene3D G3DSA:3.30.470.30 238 444 3.6E-76 T 23-10-2018 VMUT_0096 7723022838c7f4e0eb91ee5575c176f1 606 Pfam PF04679 ATP dependent DNA ligase C terminal region 467 577 2.0E-20 T 23-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 VMUT_0096 7723022838c7f4e0eb91ee5575c176f1 606 Gene3D G3DSA:2.40.50.140 445 604 6.9E-57 T 23-10-2018 VMUT_0096 7723022838c7f4e0eb91ee5575c176f1 606 Pfam PF01068 ATP dependent DNA ligase domain 241 442 3.8E-66 T 23-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 VMUT_0096 7723022838c7f4e0eb91ee5575c176f1 606 Hamap MF_00407 DNA ligase [lig]. 7 593 32.342 T 23-10-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 VMUT_1822 cb00c3ee151f2d598a7aa092b90f1af1 420 SMART SM00852 185 327 7.2E-39 T 23-10-2018 IPR001453 MoaB/Mog domain VMUT_1822 cb00c3ee151f2d598a7aa092b90f1af1 420 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 182 323 9.6E-31 T 23-10-2018 IPR001453 MoaB/Mog domain VMUT_1822 cb00c3ee151f2d598a7aa092b90f1af1 420 SUPERFAMILY SSF63882 9 180 3.14E-50 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VMUT_1822 cb00c3ee151f2d598a7aa092b90f1af1 420 SUPERFAMILY SSF53218 182 332 1.23E-38 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily VMUT_1822 cb00c3ee151f2d598a7aa092b90f1af1 420 Gene3D G3DSA:3.40.980.10 181 325 9.9E-94 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily VMUT_1822 cb00c3ee151f2d598a7aa092b90f1af1 420 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 262 296 - T 23-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 VMUT_1822 cb00c3ee151f2d598a7aa092b90f1af1 420 Pfam PF03453 MoeA N-terminal region (domain I and II) 15 173 2.1E-39 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VMUT_1822 cb00c3ee151f2d598a7aa092b90f1af1 420 Gene3D G3DSA:2.40.340.10 332 411 3.0E-18 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VMUT_1822 cb00c3ee151f2d598a7aa092b90f1af1 420 Pfam PF03454 MoeA C-terminal region (domain IV) 341 411 1.3E-14 T 23-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VMUT_1822 cb00c3ee151f2d598a7aa092b90f1af1 420 Gene3D G3DSA:2.170.190.11 50 147 9.9E-94 T 23-10-2018 VMUT_1822 cb00c3ee151f2d598a7aa092b90f1af1 420 Gene3D G3DSA:3.90.105.10 31 180 9.9E-94 T 23-10-2018 VMUT_1822 cb00c3ee151f2d598a7aa092b90f1af1 420 Pfam PF00994 Probable molybdopterin binding domain 185 327 3.7E-26 T 23-10-2018 IPR001453 MoaB/Mog domain VMUT_1822 cb00c3ee151f2d598a7aa092b90f1af1 420 SUPERFAMILY SSF63867 336 415 3.4E-17 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 Pfam PF01131 DNA topoisomerase 833 1244 6.4E-81 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 Pfam PF01751 Toprim domain 645 815 8.8E-20 T 23-10-2018 IPR006171 TOPRIM domain VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 TIGRFAM TIGR01054 rgy: reverse gyrase 7 1251 0.0 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 Hamap MF_01125 Reverse gyrase [rgy]. 4 1256 56.949 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 Gene3D G3DSA:1.10.460.10 836 1248 7.9E-137 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 Gene3D G3DSA:3.40.50.140 641 698 6.3E-5 T 23-10-2018 VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 SMART SM00437 939 1204 5.5E-83 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 SMART SM00487 82 330 2.4E-19 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 Gene3D G3DSA:3.40.50.300 323 503 1.7E-28 T 23-10-2018 VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 Gene3D G3DSA:3.40.50.300 536 627 1.1E-12 T 23-10-2018 VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 Gene3D G3DSA:3.40.50.140 746 835 3.1E-19 T 23-10-2018 VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 Pfam PF00270 DEAD/DEAH box helicase 92 231 3.0E-13 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 SMART SM00493 642 805 4.9E-13 T 23-10-2018 IPR006171 TOPRIM domain VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 SUPERFAMILY SSF56712 641 1250 2.75E-126 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 SMART SM00436 806 893 6.7E-36 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 SUPERFAMILY SSF52540 328 620 1.87E-28 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 779 792 1.1E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1164 1178 1.1E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 865 883 1.1E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 981 990 1.1E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1064 1080 1.1E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 SMART SM00382 99 272 3.2E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 Gene3D G3DSA:1.10.290.10 949 1075 7.9E-137 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 Gene3D G3DSA:3.40.50.300 65 320 9.4E-72 T 23-10-2018 VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 Gene3D G3DSA:2.60.510.20 887 1148 7.9E-137 T 23-10-2018 VMUT_0643 9fda946b6f2c0e725b353252d3089a8e 1263 SUPERFAMILY SSF52540 8 223 8.11E-28 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0384 15bb5c7264bd88602d0fe7dc01fb5084 657 SUPERFAMILY SSF103501 5 232 3.66E-9 T 23-10-2018 IPR036197 NarG-like superfamily VMUT_0384 15bb5c7264bd88602d0fe7dc01fb5084 657 Gene3D G3DSA:1.10.1060.10 247 366 4.6E-10 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VMUT_0384 15bb5c7264bd88602d0fe7dc01fb5084 657 Pfam PF13183 4Fe-4S dicluster domain 275 342 1.1E-10 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_0384 15bb5c7264bd88602d0fe7dc01fb5084 657 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 329 340 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_0384 15bb5c7264bd88602d0fe7dc01fb5084 657 Pfam PF02754 Cysteine-rich domain 537 621 3.4E-13 T 23-10-2018 IPR004017 Cysteine-rich domain VMUT_0384 15bb5c7264bd88602d0fe7dc01fb5084 657 Pfam PF02754 Cysteine-rich domain 408 495 6.5E-11 T 23-10-2018 IPR004017 Cysteine-rich domain VMUT_0384 15bb5c7264bd88602d0fe7dc01fb5084 657 SUPERFAMILY SSF46548 273 359 7.15E-19 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VMUT_1524 623dc52ba62d087e54803d29fc4e0bb4 416 ProSitePatterns PS01244 Aconitase family signature 2. 347 360 - T 23-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 VMUT_1524 623dc52ba62d087e54803d29fc4e0bb4 416 Pfam PF00330 Aconitase family (aconitate hydratase) 28 406 4.3E-80 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VMUT_1524 623dc52ba62d087e54803d29fc4e0bb4 416 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 4 412 2.8E-145 T 23-10-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 VMUT_1524 623dc52ba62d087e54803d29fc4e0bb4 416 Gene3D G3DSA:3.30.499.20 4 267 1.5E-85 T 23-10-2018 VMUT_1524 623dc52ba62d087e54803d29fc4e0bb4 416 Gene3D G3DSA:3.30.499.10 270 414 1.1E-52 T 23-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 VMUT_1524 623dc52ba62d087e54803d29fc4e0bb4 416 PRINTS PR00415 Aconitase family signature 111 124 1.2E-13 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VMUT_1524 623dc52ba62d087e54803d29fc4e0bb4 416 PRINTS PR00415 Aconitase family signature 201 214 1.2E-13 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VMUT_1524 623dc52ba62d087e54803d29fc4e0bb4 416 PRINTS PR00415 Aconitase family signature 125 140 1.2E-13 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VMUT_1524 623dc52ba62d087e54803d29fc4e0bb4 416 PRINTS PR00415 Aconitase family signature 347 360 1.2E-13 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VMUT_1524 623dc52ba62d087e54803d29fc4e0bb4 416 PRINTS PR00415 Aconitase family signature 187 200 1.2E-13 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VMUT_1524 623dc52ba62d087e54803d29fc4e0bb4 416 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 3 412 1.9E-166 T 23-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 VMUT_1524 623dc52ba62d087e54803d29fc4e0bb4 416 Hamap MF_01027 3-isopropylmalate dehydratase large subunit [leuC]. 3 414 46.332 T 23-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 VMUT_1524 623dc52ba62d087e54803d29fc4e0bb4 416 ProSitePatterns PS00450 Aconitase family signature 1. 289 305 - T 23-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 VMUT_1524 623dc52ba62d087e54803d29fc4e0bb4 416 SUPERFAMILY SSF53732 1 414 4.45E-128 T 23-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 VMUT_0318 fc7daf2d372ef99c3716d48fe1acbee3 461 Gene3D G3DSA:1.10.4100.10 17 441 3.2E-118 T 23-10-2018 VMUT_0318 fc7daf2d372ef99c3716d48fe1acbee3 461 Pfam PF03972 MmgE/PrpD family 9 448 5.1E-137 T 23-10-2018 IPR005656 MmgE/PrpD GO:0016829 VMUT_0318 fc7daf2d372ef99c3716d48fe1acbee3 461 SUPERFAMILY SSF103378 5 453 1.31E-128 T 23-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 VMUT_0318 fc7daf2d372ef99c3716d48fe1acbee3 461 Gene3D G3DSA:3.30.1330.120 269 407 3.2E-118 T 23-10-2018 VMUT_1935 153887710e16b0b3a8091a8fc829c090 726 Gene3D G3DSA:3.30.1330.10 372 545 1.3E-49 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily VMUT_1935 153887710e16b0b3a8091a8fc829c090 726 Gene3D G3DSA:3.30.1330.10 29 176 1.3E-107 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily VMUT_1935 153887710e16b0b3a8091a8fc829c090 726 SUPERFAMILY SSF56042 556 715 5.08E-34 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily VMUT_1935 153887710e16b0b3a8091a8fc829c090 726 Gene3D G3DSA:3.90.650.10 554 723 3.8E-34 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily VMUT_1935 153887710e16b0b3a8091a8fc829c090 726 Gene3D G3DSA:3.90.650.10 14 338 1.3E-107 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily VMUT_1935 153887710e16b0b3a8091a8fc829c090 726 SUPERFAMILY SSF55326 5 174 8.82E-41 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily VMUT_1935 153887710e16b0b3a8091a8fc829c090 726 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 726 218.922 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 VMUT_1935 153887710e16b0b3a8091a8fc829c090 726 Pfam PF00586 AIR synthase related protein, N-terminal domain 72 172 1.9E-20 T 23-10-2018 IPR016188 PurM-like, N-terminal domain VMUT_1935 153887710e16b0b3a8091a8fc829c090 726 Pfam PF00586 AIR synthase related protein, N-terminal domain 437 542 2.4E-18 T 23-10-2018 IPR016188 PurM-like, N-terminal domain VMUT_1935 153887710e16b0b3a8091a8fc829c090 726 SUPERFAMILY SSF56042 181 403 4.04E-48 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily VMUT_1935 153887710e16b0b3a8091a8fc829c090 726 SUPERFAMILY SSF55326 376 549 6.28E-42 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily VMUT_1935 153887710e16b0b3a8091a8fc829c090 726 Pfam PF02769 AIR synthase related protein, C-terminal domain 185 333 3.5E-28 T 23-10-2018 IPR010918 PurM-like, C-terminal domain VMUT_1935 153887710e16b0b3a8091a8fc829c090 726 Pfam PF02769 AIR synthase related protein, C-terminal domain 559 692 1.7E-14 T 23-10-2018 IPR010918 PurM-like, C-terminal domain VMUT_1935 153887710e16b0b3a8091a8fc829c090 726 PIRSF PIRSF001587 1 725 4.4E-224 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 VMUT_1935 153887710e16b0b3a8091a8fc829c090 726 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 3 721 8.9E-240 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 VMUT_1866 48df1d719672e015ceabb725ab222e2f 702 Gene3D G3DSA:3.40.50.300 353 466 2.2E-12 T 23-10-2018 VMUT_1866 48df1d719672e015ceabb725ab222e2f 702 Gene3D G3DSA:3.40.50.300 491 695 6.9E-15 T 23-10-2018 VMUT_1866 48df1d719672e015ceabb725ab222e2f 702 SUPERFAMILY SSF52540 360 660 1.68E-32 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1866 48df1d719672e015ceabb725ab222e2f 702 SMART SM00382 378 646 1.1E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_1866 48df1d719672e015ceabb725ab222e2f 702 Pfam PF01935 Domain of unknown function DUF87 378 420 7.4E-7 T 23-10-2018 IPR002789 Helicase HerA, central domain VMUT_2039 33584ee850331f99442866d275514e1b 436 Gene3D G3DSA:3.30.420.40 7 431 4.4E-181 T 23-10-2018 VMUT_2039 33584ee850331f99442866d275514e1b 436 SMART SM00268 10 436 0.0064 T 23-10-2018 IPR004000 Actin family VMUT_2039 33584ee850331f99442866d275514e1b 436 Pfam PF00022 Actin 287 413 1.4E-5 T 23-10-2018 IPR004000 Actin family VMUT_2039 33584ee850331f99442866d275514e1b 436 SUPERFAMILY SSF53067 181 416 2.47E-19 T 23-10-2018 VMUT_2039 33584ee850331f99442866d275514e1b 436 Gene3D G3DSA:3.30.420.570 180 402 4.4E-181 T 23-10-2018 VMUT_1802 4948c73e7b6b27b0adafad56296480d8 296 SUPERFAMILY SSF64182 2 267 3.14E-39 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily VMUT_1802 4948c73e7b6b27b0adafad56296480d8 296 Pfam PF02272 DHHA1 domain 212 273 4.4E-7 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 VMUT_1802 4948c73e7b6b27b0adafad56296480d8 296 Pfam PF01368 DHH family 25 125 1.4E-9 T 23-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 VMUT_1802 4948c73e7b6b27b0adafad56296480d8 296 Gene3D G3DSA:3.90.1640.10 1 171 2.7E-27 T 23-10-2018 VMUT_1742 7d9e8ecbbb9078afbe6f69f652758b8c 336 SUPERFAMILY SSF57783 36 83 2.38E-16 T 23-10-2018 VMUT_1742 7d9e8ecbbb9078afbe6f69f652758b8c 336 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 34 333 38.274 T 23-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea VMUT_1742 7d9e8ecbbb9078afbe6f69f652758b8c 336 SUPERFAMILY SSF47954 243 334 6.53E-27 T 23-10-2018 IPR036915 Cyclin-like superfamily VMUT_1742 7d9e8ecbbb9078afbe6f69f652758b8c 336 Pfam PF08271 TFIIB zinc-binding 39 80 1.5E-16 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type VMUT_1742 7d9e8ecbbb9078afbe6f69f652758b8c 336 Pfam PF00382 Transcription factor TFIIB repeat 248 318 7.9E-17 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 VMUT_1742 7d9e8ecbbb9078afbe6f69f652758b8c 336 Pfam PF00382 Transcription factor TFIIB repeat 155 224 1.6E-15 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 VMUT_1742 7d9e8ecbbb9078afbe6f69f652758b8c 336 PRINTS PR00685 Transcription initiation factor IIB signature 194 213 6.1E-48 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 VMUT_1742 7d9e8ecbbb9078afbe6f69f652758b8c 336 PRINTS PR00685 Transcription initiation factor IIB signature 281 297 6.1E-48 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 VMUT_1742 7d9e8ecbbb9078afbe6f69f652758b8c 336 PRINTS PR00685 Transcription initiation factor IIB signature 74 87 6.1E-48 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 VMUT_1742 7d9e8ecbbb9078afbe6f69f652758b8c 336 PRINTS PR00685 Transcription initiation factor IIB signature 313 327 6.1E-48 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 VMUT_1742 7d9e8ecbbb9078afbe6f69f652758b8c 336 PRINTS PR00685 Transcription initiation factor IIB signature 52 72 6.1E-48 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 VMUT_1742 7d9e8ecbbb9078afbe6f69f652758b8c 336 PRINTS PR00685 Transcription initiation factor IIB signature 87 108 6.1E-48 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 VMUT_1742 7d9e8ecbbb9078afbe6f69f652758b8c 336 PRINTS PR00685 Transcription initiation factor IIB signature 220 235 6.1E-48 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 VMUT_1742 7d9e8ecbbb9078afbe6f69f652758b8c 336 PRINTS PR00685 Transcription initiation factor IIB signature 247 265 6.1E-48 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 VMUT_1742 7d9e8ecbbb9078afbe6f69f652758b8c 336 Gene3D G3DSA:1.10.472.170 38 235 2.7E-56 T 23-10-2018 VMUT_1742 7d9e8ecbbb9078afbe6f69f652758b8c 336 SUPERFAMILY SSF47954 148 240 3.14E-24 T 23-10-2018 IPR036915 Cyclin-like superfamily VMUT_1742 7d9e8ecbbb9078afbe6f69f652758b8c 336 SMART SM00385 246 327 5.7E-10 T 23-10-2018 IPR013763 Cyclin-like VMUT_1742 7d9e8ecbbb9078afbe6f69f652758b8c 336 SMART SM00385 152 233 3.0E-12 T 23-10-2018 IPR013763 Cyclin-like VMUT_1742 7d9e8ecbbb9078afbe6f69f652758b8c 336 Gene3D G3DSA:1.10.472.10 243 336 3.0E-26 T 23-10-2018 VMUT_1742 7d9e8ecbbb9078afbe6f69f652758b8c 336 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 280 295 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 VMUT_1535 be76f03fb01e6099d1392f9f33561fa8 260 SUPERFAMILY SSF52440 2 69 7.77E-11 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily VMUT_1535 be76f03fb01e6099d1392f9f33561fa8 260 Gene3D G3DSA:3.30.470.80 150 259 2.1E-36 T 23-10-2018 VMUT_1535 be76f03fb01e6099d1392f9f33561fa8 260 SUPERFAMILY SSF56059 59 258 6.7E-43 T 23-10-2018 VMUT_1535 be76f03fb01e6099d1392f9f33561fa8 260 Pfam PF08443 RimK-like ATP-grasp domain 69 254 2.6E-33 T 23-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 VMUT_1535 be76f03fb01e6099d1392f9f33561fa8 260 Gene3D G3DSA:3.40.50.20 1 84 2.5E-16 T 23-10-2018 VMUT_1535 be76f03fb01e6099d1392f9f33561fa8 260 Gene3D G3DSA:3.30.1490.20 94 149 4.6E-13 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VMUT_1535 be76f03fb01e6099d1392f9f33561fa8 260 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 4 254 8.9E-66 T 23-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 VMUT_0164 d5cd91f9353565404a8c12fa7a5dfc0c 361 Gene3D G3DSA:3.40.50.300 1 210 1.4E-40 T 23-10-2018 VMUT_0164 d5cd91f9353565404a8c12fa7a5dfc0c 361 Gene3D G3DSA:1.10.8.60 212 286 3.0E-23 T 23-10-2018 VMUT_0164 d5cd91f9353565404a8c12fa7a5dfc0c 361 Pfam PF01637 ATPase domain predominantly from Archaea 18 251 3.2E-13 T 23-10-2018 IPR011579 ATPase domain GO:0005524 VMUT_0164 d5cd91f9353565404a8c12fa7a5dfc0c 361 SUPERFAMILY SSF52540 1 265 2.46E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0164 d5cd91f9353565404a8c12fa7a5dfc0c 361 Gene3D G3DSA:1.10.10.10 288 358 1.6E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_0164 d5cd91f9353565404a8c12fa7a5dfc0c 361 SUPERFAMILY SSF46785 288 358 1.27E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0963 cc593f4f391fdb8bf8126f5fcefe05f8 158 Pfam PF00380 Ribosomal protein S9/S16 33 158 1.4E-32 T 23-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 VMUT_0963 cc593f4f391fdb8bf8126f5fcefe05f8 158 Hamap MF_00532_A 30S ribosomal protein S9 [rpsI]. 28 158 34.379 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_0963 cc593f4f391fdb8bf8126f5fcefe05f8 158 TIGRFAM TIGR03627 uS9_arch: ribosomal protein uS9 28 158 1.5E-57 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_0963 cc593f4f391fdb8bf8126f5fcefe05f8 158 ProSitePatterns PS00360 Ribosomal protein S9 signature. 93 111 - T 23-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 VMUT_0963 cc593f4f391fdb8bf8126f5fcefe05f8 158 Gene3D G3DSA:3.30.230.10 23 158 4.0E-46 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup VMUT_0963 cc593f4f391fdb8bf8126f5fcefe05f8 158 SUPERFAMILY SSF54211 28 158 3.75E-35 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VMUT_1059 03bd93882fb26deb65101fa7f6ea783d 380 Pfam PF00534 Glycosyl transferases group 1 187 339 8.6E-23 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 VMUT_1059 03bd93882fb26deb65101fa7f6ea783d 380 Gene3D G3DSA:3.40.50.2000 6 191 4.5E-6 T 23-10-2018 VMUT_1059 03bd93882fb26deb65101fa7f6ea783d 380 Gene3D G3DSA:3.40.50.2000 192 356 9.5E-28 T 23-10-2018 VMUT_1059 03bd93882fb26deb65101fa7f6ea783d 380 Pfam PF13439 Glycosyltransferase Family 4 22 186 2.9E-9 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 VMUT_1059 03bd93882fb26deb65101fa7f6ea783d 380 SUPERFAMILY SSF53756 16 373 1.49E-48 T 23-10-2018 VMUT_1883 3884ea450c946f78d66b9b39a7127afd 362 Pfam PF07282 Putative transposase DNA-binding domain 295 349 1.0E-9 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal VMUT_1883 3884ea450c946f78d66b9b39a7127afd 362 SUPERFAMILY SSF51998 214 352 4.49E-6 T 23-10-2018 VMUT_1248 71b42a2d18d8227d2c79a8de1b6b6f42 339 Pfam PF02653 Branched-chain amino acid transport system / permease component 65 327 4.1E-42 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VMUT_2007 8f8f267d04657d30daeb2644825169a5 160 SUPERFAMILY SSF52833 3 134 1.61E-44 T 23-10-2018 IPR036249 Thioredoxin-like superfamily VMUT_2007 8f8f267d04657d30daeb2644825169a5 160 Gene3D G3DSA:3.40.30.10 5 154 1.8E-42 T 23-10-2018 VMUT_2007 8f8f267d04657d30daeb2644825169a5 160 PIRSF PIRSF000239 1 155 2.7E-27 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 VMUT_2007 8f8f267d04657d30daeb2644825169a5 160 Pfam PF00578 AhpC/TSA family 7 127 3.6E-37 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 VMUT_1853 7a15603e3d40650a956aba787022fb0e 394 SUPERFAMILY SSF63411 2 198 4.54E-48 T 23-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 VMUT_1853 7a15603e3d40650a956aba787022fb0e 394 Pfam PF00675 Insulinase (Peptidase family M16) 23 151 1.2E-18 T 23-10-2018 IPR011765 Peptidase M16, N-terminal VMUT_1853 7a15603e3d40650a956aba787022fb0e 394 SUPERFAMILY SSF63411 216 374 2.02E-8 T 23-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 VMUT_1853 7a15603e3d40650a956aba787022fb0e 394 Gene3D G3DSA:3.30.830.10 215 383 5.0E-7 T 23-10-2018 VMUT_1853 7a15603e3d40650a956aba787022fb0e 394 Gene3D G3DSA:3.30.830.10 3 209 3.4E-51 T 23-10-2018 VMUT_1853 7a15603e3d40650a956aba787022fb0e 394 Pfam PF05193 Peptidase M16 inactive domain 161 314 2.6E-11 T 23-10-2018 IPR007863 Peptidase M16, C-terminal VMUT_0793 30bc379ff6793e290f58d789061372fa 78 Gene3D G3DSA:3.40.50.300 1 78 1.1E-16 T 23-10-2018 VMUT_0793 30bc379ff6793e290f58d789061372fa 78 SUPERFAMILY SSF52540 1 70 6.89E-14 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1267 96a508cacb5bdc7fa52cecfa32848042 188 Gene3D G3DSA:1.10.10.10 7 69 1.7E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_1267 96a508cacb5bdc7fa52cecfa32848042 188 SUPERFAMILY SSF46785 5 67 5.86E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_1267 96a508cacb5bdc7fa52cecfa32848042 188 Gene3D G3DSA:3.30.1360.30 70 179 1.7E-19 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 VMUT_1267 96a508cacb5bdc7fa52cecfa32848042 188 SUPERFAMILY SSF55261 88 184 3.99E-8 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 VMUT_1135 ab0d11406bdde4d0f90bb14b369ac8a4 273 Gene3D G3DSA:3.40.50.620 4 272 2.0E-67 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_1135 ab0d11406bdde4d0f90bb14b369ac8a4 273 SUPERFAMILY SSF52402 4 266 4.4E-57 T 23-10-2018 VMUT_1135 ab0d11406bdde4d0f90bb14b369ac8a4 273 SMART SM00893 26 213 2.4E-35 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 VMUT_1135 ab0d11406bdde4d0f90bb14b369ac8a4 273 Pfam PF01012 Electron transfer flavoprotein domain 29 203 7.1E-37 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 VMUT_1135 ab0d11406bdde4d0f90bb14b369ac8a4 273 PIRSF PIRSF000090 4 272 2.4E-69 T 23-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 VMUT_2324 0d91f04cd20bdde1e6fd2f8ee342ead7 356 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 197 218 4.7E-16 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 VMUT_2324 0d91f04cd20bdde1e6fd2f8ee342ead7 356 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 240 250 4.7E-16 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 VMUT_2324 0d91f04cd20bdde1e6fd2f8ee342ead7 356 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 120 139 4.7E-16 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 VMUT_2324 0d91f04cd20bdde1e6fd2f8ee342ead7 356 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 67 83 4.7E-16 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 VMUT_2324 0d91f04cd20bdde1e6fd2f8ee342ead7 356 Pfam PF00579 tRNA synthetases class I (W and Y) 56 332 9.9E-25 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_2324 0d91f04cd20bdde1e6fd2f8ee342ead7 356 SUPERFAMILY SSF52374 3 344 3.9E-74 T 23-10-2018 VMUT_2324 0d91f04cd20bdde1e6fd2f8ee342ead7 356 Gene3D G3DSA:3.40.50.620 1 243 2.8E-84 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_2324 0d91f04cd20bdde1e6fd2f8ee342ead7 356 Gene3D G3DSA:1.10.240.10 244 354 9.3E-42 T 23-10-2018 VMUT_2324 0d91f04cd20bdde1e6fd2f8ee342ead7 356 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 56 344 1.6E-73 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 VMUT_2324 0d91f04cd20bdde1e6fd2f8ee342ead7 356 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 63 72 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_1137 73878d70adf50ca14bed9fc9085bccef 411 SUPERFAMILY SSF102645 190 408 6.54E-48 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 VMUT_1137 73878d70adf50ca14bed9fc9085bccef 411 Pfam PF02441 Flavoprotein 21 186 7.4E-33 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 VMUT_1137 73878d70adf50ca14bed9fc9085bccef 411 SUPERFAMILY SSF52507 17 187 5.89E-44 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 VMUT_1137 73878d70adf50ca14bed9fc9085bccef 411 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 193 378 1.9E-40 T 23-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 VMUT_1137 73878d70adf50ca14bed9fc9085bccef 411 Gene3D G3DSA:3.40.50.10300 190 410 3.1E-48 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 VMUT_1137 73878d70adf50ca14bed9fc9085bccef 411 Gene3D G3DSA:3.40.50.1950 20 189 2.8E-41 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 VMUT_1137 73878d70adf50ca14bed9fc9085bccef 411 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 19 403 8.3E-90 T 23-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 VMUT_0382 f3203aed55bda6ed1c04e15009ae4917 264 Gene3D G3DSA:3.40.50.620 1 263 3.6E-74 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_0382 f3203aed55bda6ed1c04e15009ae4917 264 SMART SM00893 20 218 4.8E-45 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 VMUT_0382 f3203aed55bda6ed1c04e15009ae4917 264 SUPERFAMILY SSF52402 1 251 2.43E-65 T 23-10-2018 VMUT_0382 f3203aed55bda6ed1c04e15009ae4917 264 Pfam PF01012 Electron transfer flavoprotein domain 23 213 5.1E-45 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 VMUT_0382 f3203aed55bda6ed1c04e15009ae4917 264 PIRSF PIRSF000090 1 262 9.0E-73 T 23-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 VMUT_0173 9cc8d6d1e58d2ba40823e8e36b08fe71 354 Gene3D G3DSA:3.50.50.60 130 280 5.7E-51 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0173 9cc8d6d1e58d2ba40823e8e36b08fe71 354 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 19 41 1.8E-11 T 23-10-2018 VMUT_0173 9cc8d6d1e58d2ba40823e8e36b08fe71 354 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 171 196 1.8E-11 T 23-10-2018 VMUT_0173 9cc8d6d1e58d2ba40823e8e36b08fe71 354 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 273 287 1.8E-11 T 23-10-2018 VMUT_0173 9cc8d6d1e58d2ba40823e8e36b08fe71 354 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 315 322 1.8E-11 T 23-10-2018 VMUT_0173 9cc8d6d1e58d2ba40823e8e36b08fe71 354 SUPERFAMILY SSF51971 265 347 2.24E-10 T 23-10-2018 VMUT_0173 9cc8d6d1e58d2ba40823e8e36b08fe71 354 SUPERFAMILY SSF51971 18 280 1.12E-57 T 23-10-2018 VMUT_0173 9cc8d6d1e58d2ba40823e8e36b08fe71 354 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 300 322 3.3E-17 T 23-10-2018 VMUT_0173 9cc8d6d1e58d2ba40823e8e36b08fe71 354 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 20 39 3.3E-17 T 23-10-2018 VMUT_0173 9cc8d6d1e58d2ba40823e8e36b08fe71 354 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 3.3E-17 T 23-10-2018 VMUT_0173 9cc8d6d1e58d2ba40823e8e36b08fe71 354 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 272 288 3.3E-17 T 23-10-2018 VMUT_0173 9cc8d6d1e58d2ba40823e8e36b08fe71 354 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 335 2.4E-34 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VMUT_0173 9cc8d6d1e58d2ba40823e8e36b08fe71 354 Gene3D G3DSA:3.50.50.60 21 342 5.7E-51 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_1115 022fbebfeda75152153b1466eec58ca7 525 Pfam PF12704 MacB-like periplasmic core domain 19 193 8.3E-7 T 23-10-2018 IPR025857 MacB-like periplasmic core domain VMUT_0394 2ecba4d8bc902f76e5a3fbab5cf23502 572 SUPERFAMILY SSF102114 143 361 1.07E-38 T 23-10-2018 VMUT_0394 2ecba4d8bc902f76e5a3fbab5cf23502 572 Pfam PF13394 4Fe-4S single cluster domain 161 242 1.4E-5 T 23-10-2018 VMUT_0394 2ecba4d8bc902f76e5a3fbab5cf23502 572 Gene3D G3DSA:3.20.20.70 149 394 6.8E-35 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_0394 2ecba4d8bc902f76e5a3fbab5cf23502 572 Pfam PF04055 Radical SAM superfamily 160 327 5.0E-22 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_0725 4aaba88a829e250eabd8352e9d7c793e 439 Gene3D G3DSA:3.90.1150.10 21 427 7.1E-132 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VMUT_0725 4aaba88a829e250eabd8352e9d7c793e 439 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 241 278 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VMUT_0725 4aaba88a829e250eabd8352e9d7c793e 439 SUPERFAMILY SSF53383 16 432 2.33E-111 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VMUT_0725 4aaba88a829e250eabd8352e9d7c793e 439 Pfam PF00202 Aminotransferase class-III 23 427 6.2E-94 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VMUT_0725 4aaba88a829e250eabd8352e9d7c793e 439 PIRSF PIRSF000521 2 131 1.1E-9 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VMUT_0725 4aaba88a829e250eabd8352e9d7c793e 439 PIRSF PIRSF000521 124 432 1.4E-39 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VMUT_0725 4aaba88a829e250eabd8352e9d7c793e 439 Gene3D G3DSA:3.40.640.10 59 325 7.1E-132 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VMUT_0340 531320b53d3a6a387709417959fe9f7a 257 SUPERFAMILY SSF52540 6 247 1.05E-61 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0340 531320b53d3a6a387709417959fe9f7a 257 Gene3D G3DSA:3.40.50.300 3 241 7.2E-61 T 23-10-2018 VMUT_0340 531320b53d3a6a387709417959fe9f7a 257 SMART SM00382 34 233 1.8E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0340 531320b53d3a6a387709417959fe9f7a 257 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VMUT_0340 531320b53d3a6a387709417959fe9f7a 257 Pfam PF00005 ABC transporter 25 166 1.9E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_2093 cb6f349b139df41be5611fe11b03d8c8 904 PRINTS PR00415 Aconitase family signature 148 161 1.6E-33 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VMUT_2093 cb6f349b139df41be5611fe11b03d8c8 904 PRINTS PR00415 Aconitase family signature 282 295 1.6E-33 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VMUT_2093 cb6f349b139df41be5611fe11b03d8c8 904 PRINTS PR00415 Aconitase family signature 296 309 1.6E-33 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VMUT_2093 cb6f349b139df41be5611fe11b03d8c8 904 PRINTS PR00415 Aconitase family signature 436 447 1.6E-33 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VMUT_2093 cb6f349b139df41be5611fe11b03d8c8 904 PRINTS PR00415 Aconitase family signature 376 390 1.6E-33 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VMUT_2093 cb6f349b139df41be5611fe11b03d8c8 904 PRINTS PR00415 Aconitase family signature 498 511 1.6E-33 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VMUT_2093 cb6f349b139df41be5611fe11b03d8c8 904 PRINTS PR00415 Aconitase family signature 206 219 1.6E-33 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VMUT_2093 cb6f349b139df41be5611fe11b03d8c8 904 PRINTS PR00415 Aconitase family signature 172 180 1.6E-33 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VMUT_2093 cb6f349b139df41be5611fe11b03d8c8 904 PRINTS PR00415 Aconitase family signature 220 235 1.6E-33 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VMUT_2093 cb6f349b139df41be5611fe11b03d8c8 904 SUPERFAMILY SSF53732 9 620 1.15E-205 T 23-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 VMUT_2093 cb6f349b139df41be5611fe11b03d8c8 904 Gene3D G3DSA:1.10.1440.20 596 657 1.0E-16 T 23-10-2018 VMUT_2093 cb6f349b139df41be5611fe11b03d8c8 904 ProSitePatterns PS00450 Aconitase family signature 1. 432 448 - T 23-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 VMUT_2093 cb6f349b139df41be5611fe11b03d8c8 904 Gene3D G3DSA:3.20.19.10 660 901 5.1E-101 T 23-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 VMUT_2093 cb6f349b139df41be5611fe11b03d8c8 904 Gene3D G3DSA:3.30.499.10 377 595 3.1E-85 T 23-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 VMUT_2093 cb6f349b139df41be5611fe11b03d8c8 904 Gene3D G3DSA:3.30.499.20 8 376 1.1E-149 T 23-10-2018 VMUT_2093 cb6f349b139df41be5611fe11b03d8c8 904 SUPERFAMILY SSF52016 637 899 1.69E-84 T 23-10-2018 VMUT_2093 cb6f349b139df41be5611fe11b03d8c8 904 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 21 900 0.0 T 23-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 VMUT_2093 cb6f349b139df41be5611fe11b03d8c8 904 Pfam PF00694 Aconitase C-terminal domain 699 827 1.7E-38 T 23-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 VMUT_2093 cb6f349b139df41be5611fe11b03d8c8 904 Pfam PF00330 Aconitase family (aconitate hydratase) 78 567 3.0E-165 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VMUT_1215 009789eb5115653e3d6e6553b380849b 190 Gene3D G3DSA:1.10.150.280 86 181 3.5E-38 T 23-10-2018 VMUT_1215 009789eb5115653e3d6e6553b380849b 190 Pfam PF04919 Protein of unknown function (DUF655) 8 189 3.9E-59 T 23-10-2018 IPR007003 Protein of unknown function DUF655 VMUT_1215 009789eb5115653e3d6e6553b380849b 190 SUPERFAMILY SSF160975 8 190 2.48E-77 T 23-10-2018 VMUT_1215 009789eb5115653e3d6e6553b380849b 190 Gene3D G3DSA:2.40.50.140 8 85 3.0E-22 T 23-10-2018 VMUT_0882 cdba9c036f724e3d23c98d90790a6ebc 108 SMART SM01380 7 87 6.3E-30 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0882 cdba9c036f724e3d23c98d90790a6ebc 108 ProSitePatterns PS01144 Ribosomal protein L31e signature. 52 66 - T 23-10-2018 IPR020052 Ribosomal protein L31e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0882 cdba9c036f724e3d23c98d90790a6ebc 108 Hamap MF_00410 50S ribosomal protein L31e [rpl31e]. 7 91 22.758 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0882 cdba9c036f724e3d23c98d90790a6ebc 108 ProDom PD006030 RIBOSOMAL 60S L31 RIBONUCLEOPROTEIN L31E 50S L31 SUBUNIT STRAIN PHOSPHORYLATION 7 59 2.0E-12 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0882 cdba9c036f724e3d23c98d90790a6ebc 108 Gene3D G3DSA:3.10.440.10 4 94 1.6E-31 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0882 cdba9c036f724e3d23c98d90790a6ebc 108 Pfam PF01198 Ribosomal protein L31e 10 80 3.2E-16 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0882 cdba9c036f724e3d23c98d90790a6ebc 108 SUPERFAMILY SSF54575 10 90 6.02E-27 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_2062 03becc892764bc140f7bd2adf5d77d11 150 Gene3D G3DSA:3.30.300.20 76 143 3.0E-22 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta VMUT_2062 03becc892764bc140f7bd2adf5d77d11 150 Gene3D G3DSA:3.30.300.20 2 74 6.6E-26 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta VMUT_2062 03becc892764bc140f7bd2adf5d77d11 150 Pfam PF13184 NusA-like KH domain 35 95 2.8E-11 T 23-10-2018 IPR025249 KH domain, NusA-like GO:0003723 VMUT_2062 03becc892764bc140f7bd2adf5d77d11 150 SUPERFAMILY SSF54814 77 140 5.42E-10 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 VMUT_2062 03becc892764bc140f7bd2adf5d77d11 150 SUPERFAMILY SSF54814 14 75 4.19E-10 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 VMUT_2062 03becc892764bc140f7bd2adf5d77d11 150 SMART SM00322 33 114 4.2E-4 T 23-10-2018 IPR004087 K Homology domain GO:0003676 VMUT_2062 03becc892764bc140f7bd2adf5d77d11 150 Hamap MF_00945_A Transcription termination/antitermination protein NusA [nusA]. 2 144 29.912 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal VMUT_2062 03becc892764bc140f7bd2adf5d77d11 150 TIGRFAM TIGR01952 nusA_arch: NusA family KH domain protein, archaeal 3 144 2.0E-46 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal VMUT_2101 22408528f14441f4c762dd21a063f96d 385 Gene3D G3DSA:3.10.580.10 127 287 1.4E-32 T 23-10-2018 VMUT_2101 22408528f14441f4c762dd21a063f96d 385 SMART SM00116 217 264 2.5E-10 T 23-10-2018 IPR000644 CBS domain VMUT_2101 22408528f14441f4c762dd21a063f96d 385 SMART SM00116 138 185 6.9E-8 T 23-10-2018 IPR000644 CBS domain VMUT_2101 22408528f14441f4c762dd21a063f96d 385 SMART SM00116 73 121 9.3E-8 T 23-10-2018 IPR000644 CBS domain VMUT_2101 22408528f14441f4c762dd21a063f96d 385 SMART SM00116 13 61 0.01 T 23-10-2018 IPR000644 CBS domain VMUT_2101 22408528f14441f4c762dd21a063f96d 385 Gene3D G3DSA:3.10.580.10 2 126 1.5E-24 T 23-10-2018 VMUT_2101 22408528f14441f4c762dd21a063f96d 385 SUPERFAMILY SSF54631 125 265 3.64E-30 T 23-10-2018 VMUT_2101 22408528f14441f4c762dd21a063f96d 385 SUPERFAMILY SSF54631 3 122 4.55E-26 T 23-10-2018 VMUT_2101 22408528f14441f4c762dd21a063f96d 385 SUPERFAMILY SSF69754 282 375 8.5E-6 T 23-10-2018 IPR036567 Ribosome hibernation promotion factor-like VMUT_2101 22408528f14441f4c762dd21a063f96d 385 Pfam PF00571 CBS domain 131 184 2.5E-11 T 23-10-2018 IPR000644 CBS domain VMUT_2101 22408528f14441f4c762dd21a063f96d 385 Pfam PF00571 CBS domain 6 59 1.0E-8 T 23-10-2018 IPR000644 CBS domain VMUT_2101 22408528f14441f4c762dd21a063f96d 385 Pfam PF00571 CBS domain 67 121 3.4E-9 T 23-10-2018 IPR000644 CBS domain VMUT_2101 22408528f14441f4c762dd21a063f96d 385 Pfam PF00571 CBS domain 211 263 1.6E-10 T 23-10-2018 IPR000644 CBS domain VMUT_1197 6eadf4865526b8e2c3e78f58dd118653 366 Gene3D G3DSA:3.30.70.20 247 334 1.3E-15 T 23-10-2018 VMUT_1197 6eadf4865526b8e2c3e78f58dd118653 366 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 257 323 9.0E-20 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 VMUT_1197 6eadf4865526b8e2c3e78f58dd118653 366 SUPERFAMILY SSF54862 259 324 1.2E-17 T 23-10-2018 VMUT_1197 6eadf4865526b8e2c3e78f58dd118653 366 Pfam PF14697 4Fe-4S dicluster domain 266 320 8.6E-11 T 23-10-2018 VMUT_1197 6eadf4865526b8e2c3e78f58dd118653 366 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 302 313 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_1197 6eadf4865526b8e2c3e78f58dd118653 366 Gene3D G3DSA:3.40.920.10 24 212 1.1E-6 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 VMUT_1110 31239f7e57aefd3595fd58540df5714a 326 Gene3D G3DSA:1.10.8.300 212 314 3.0E-24 T 23-10-2018 VMUT_1110 31239f7e57aefd3595fd58540df5714a 326 SUPERFAMILY SSF52540 6 293 1.41E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1110 31239f7e57aefd3595fd58540df5714a 326 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 44 174 1.4E-37 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 VMUT_1110 31239f7e57aefd3595fd58540df5714a 326 Gene3D G3DSA:3.40.50.300 11 211 1.5E-42 T 23-10-2018 VMUT_1110 31239f7e57aefd3595fd58540df5714a 326 SMART SM00382 41 183 4.6E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_1110 31239f7e57aefd3595fd58540df5714a 326 PIRSF PIRSF002849 5 319 6.7E-93 T 23-10-2018 VMUT_0557 2ecd64307e6171181def355fa0ff9110 424 Pfam PF00361 Proton-conducting membrane transporter 99 368 3.1E-24 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_0673 ac94b54d47c3f899b4d21ea22bb42608 258 Pfam PF04016 Putative heavy-metal chelation 122 246 3.0E-29 T 23-10-2018 IPR007161 Putative heavy-metal chelation domain VMUT_0673 ac94b54d47c3f899b4d21ea22bb42608 258 Gene3D G3DSA:3.40.50.11590 121 228 4.8E-22 T 23-10-2018 VMUT_0673 ac94b54d47c3f899b4d21ea22bb42608 258 Pfam PF13938 Putative heavy-metal chelation 19 93 4.1E-8 T 23-10-2018 IPR025251 Domain of unknown function DUF4213 VMUT_0673 ac94b54d47c3f899b4d21ea22bb42608 258 SUPERFAMILY SSF159713 19 246 7.85E-43 T 23-10-2018 VMUT_0400 02f57a3c8d4dbd743d781fae210acbf8 187 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 9 185 9.5E-54 T 23-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 VMUT_0400 02f57a3c8d4dbd743d781fae210acbf8 187 SUPERFAMILY SSF53323 7 185 2.22E-38 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 VMUT_0400 02f57a3c8d4dbd743d781fae210acbf8 187 Gene3D G3DSA:3.40.920.10 6 186 2.5E-47 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 VMUT_0400 02f57a3c8d4dbd743d781fae210acbf8 187 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 16 182 1.2E-26 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 VMUT_0906 2cc0467065fdd29a85d9420cd5ff0ee1 219 Hamap MF_01318_A 50S ribosomal protein L1 [rplA]. 4 214 31.323 T 23-10-2018 IPR023669 Ribosomal protein L1, archaea GO:0003723|GO:0003735|GO:0006412|GO:0015934 VMUT_0906 2cc0467065fdd29a85d9420cd5ff0ee1 219 Gene3D G3DSA:3.30.190.20 14 211 1.5E-62 T 23-10-2018 VMUT_0906 2cc0467065fdd29a85d9420cd5ff0ee1 219 Gene3D G3DSA:3.40.50.790 60 151 1.5E-62 T 23-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich VMUT_0906 2cc0467065fdd29a85d9420cd5ff0ee1 219 SUPERFAMILY SSF56808 9 212 4.71E-53 T 23-10-2018 IPR023674 Ribosomal protein L1-like VMUT_0906 2cc0467065fdd29a85d9420cd5ff0ee1 219 Pfam PF00687 Ribosomal protein L1p/L10e family 18 209 5.4E-39 T 23-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein VMUT_0906 2cc0467065fdd29a85d9420cd5ff0ee1 219 PIRSF PIRSF002155 1 214 6.0E-54 T 23-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0906 2cc0467065fdd29a85d9420cd5ff0ee1 219 ProSitePatterns PS01199 Ribosomal protein L1 signature. 116 135 - T 23-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_2298 9b2f42e44d4981746fbf3af2cb88fd32 753 Gene3D G3DSA:3.40.50.300 250 434 2.1E-25 T 23-10-2018 VMUT_2298 9b2f42e44d4981746fbf3af2cb88fd32 753 SMART SM00490 294 377 1.3E-18 T 23-10-2018 IPR001650 Helicase, C-terminal VMUT_2298 9b2f42e44d4981746fbf3af2cb88fd32 753 Pfam PF00271 Helicase conserved C-terminal domain 277 377 7.8E-15 T 23-10-2018 IPR001650 Helicase, C-terminal VMUT_2298 9b2f42e44d4981746fbf3af2cb88fd32 753 Pfam PF09369 Domain of unknown function (DUF1998) 638 711 1.7E-12 T 23-10-2018 IPR018973 DEAD/DEAH-box helicase, putative VMUT_2298 9b2f42e44d4981746fbf3af2cb88fd32 753 Gene3D G3DSA:3.40.50.300 40 240 5.0E-41 T 23-10-2018 VMUT_2298 9b2f42e44d4981746fbf3af2cb88fd32 753 Pfam PF00270 DEAD/DEAH box helicase 63 225 4.2E-24 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 VMUT_2298 9b2f42e44d4981746fbf3af2cb88fd32 753 SUPERFAMILY SSF52540 70 387 7.54E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_2298 9b2f42e44d4981746fbf3af2cb88fd32 753 SMART SM00487 57 256 4.9E-28 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain VMUT_2238 57da00483647ecbe58d62beb98645a57 276 SUPERFAMILY SSF51735 1 151 1.03E-24 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_2238 57da00483647ecbe58d62beb98645a57 276 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 158 274 1.7E-10 T 23-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 VMUT_2238 57da00483647ecbe58d62beb98645a57 276 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 150 6.3E-24 T 23-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 VMUT_2238 57da00483647ecbe58d62beb98645a57 276 SUPERFAMILY SSF48179 157 274 5.1E-16 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VMUT_2238 57da00483647ecbe58d62beb98645a57 276 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 23-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 VMUT_2238 57da00483647ecbe58d62beb98645a57 276 Gene3D G3DSA:1.10.1040.10 152 276 5.2E-17 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VMUT_2238 57da00483647ecbe58d62beb98645a57 276 Gene3D G3DSA:3.40.50.720 1 151 8.1E-30 T 23-10-2018 VMUT_2238 57da00483647ecbe58d62beb98645a57 276 PIRSF PIRSF000103 1 276 9.6E-40 T 23-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 VMUT_0464 4e5a3f6c87774157a48499a806863fc2 100 ProSitePatterns PS00466 Zinc finger TFIIS-type signature. 61 96 - T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 VMUT_0464 4e5a3f6c87774157a48499a806863fc2 100 Pfam PF01096 Transcription factor S-II (TFIIS) 60 97 2.2E-19 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 VMUT_0464 4e5a3f6c87774157a48499a806863fc2 100 SUPERFAMILY SSF57783 38 100 2.89E-22 T 23-10-2018 VMUT_0464 4e5a3f6c87774157a48499a806863fc2 100 PIRSF PIRSF005586 1 100 7.6E-31 T 23-10-2018 IPR012164 DNA-directed RNA polymerase subunit/transcription factor S GO:0006351 VMUT_0464 4e5a3f6c87774157a48499a806863fc2 100 Gene3D G3DSA:2.20.25.10 47 100 7.9E-23 T 23-10-2018 VMUT_0464 4e5a3f6c87774157a48499a806863fc2 100 TIGRFAM TIGR01384 TFS_arch: transcription factor S 5 100 3.2E-27 T 23-10-2018 IPR006288 Transcription factor S GO:0006355 VMUT_0464 4e5a3f6c87774157a48499a806863fc2 100 SMART SM00440 59 98 1.6E-19 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 VMUT_1375 ecd8d92b738d2c7b0c9253480b0daeb5 664 SUPERFAMILY SSF51735 4 186 5.18E-64 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1375 ecd8d92b738d2c7b0c9253480b0daeb5 664 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 187 1.5E-70 T 23-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 VMUT_1375 ecd8d92b738d2c7b0c9253480b0daeb5 664 Gene3D G3DSA:1.10.12.10 606 664 3.7E-18 T 23-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal VMUT_1375 ecd8d92b738d2c7b0c9253480b0daeb5 664 Gene3D G3DSA:1.10.1040.10 192 302 3.4E-26 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VMUT_1375 ecd8d92b738d2c7b0c9253480b0daeb5 664 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 505 525 - T 23-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 VMUT_1375 ecd8d92b738d2c7b0c9253480b0daeb5 664 Gene3D G3DSA:3.90.226.10 399 605 1.9E-74 T 23-10-2018 VMUT_1375 ecd8d92b738d2c7b0c9253480b0daeb5 664 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 308 398 2.3E-21 T 23-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 VMUT_1375 ecd8d92b738d2c7b0c9253480b0daeb5 664 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 285 1.9E-24 T 23-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 VMUT_1375 ecd8d92b738d2c7b0c9253480b0daeb5 664 Gene3D G3DSA:1.10.1040.10 303 394 9.0E-27 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VMUT_1375 ecd8d92b738d2c7b0c9253480b0daeb5 664 SUPERFAMILY SSF52096 402 663 1.42E-89 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VMUT_1375 ecd8d92b738d2c7b0c9253480b0daeb5 664 Pfam PF00378 Enoyl-CoA hydratase/isomerase 417 663 1.3E-64 T 23-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VMUT_1375 ecd8d92b738d2c7b0c9253480b0daeb5 664 SUPERFAMILY SSF48179 308 402 1.11E-26 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VMUT_1375 ecd8d92b738d2c7b0c9253480b0daeb5 664 Gene3D G3DSA:3.40.50.720 1 191 4.2E-75 T 23-10-2018 VMUT_1375 ecd8d92b738d2c7b0c9253480b0daeb5 664 SUPERFAMILY SSF48179 189 294 1.45E-24 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VMUT_2047 876f7a7b7504b846b2e774dc5a25d2bb 553 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 12 528 4.3E-238 T 23-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 VMUT_2047 876f7a7b7504b846b2e774dc5a25d2bb 553 SUPERFAMILY SSF52029 216 382 7.74E-60 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily VMUT_2047 876f7a7b7504b846b2e774dc5a25d2bb 553 Gene3D G3DSA:3.50.7.10 221 372 8.8E-198 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily VMUT_2047 876f7a7b7504b846b2e774dc5a25d2bb 553 Pfam PF00118 TCP-1/cpn60 chaperonin family 39 528 9.2E-179 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 VMUT_2047 876f7a7b7504b846b2e774dc5a25d2bb 553 SUPERFAMILY SSF48592 21 528 3.4E-89 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily VMUT_2047 876f7a7b7504b846b2e774dc5a25d2bb 553 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 377 399 7.2E-32 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 VMUT_2047 876f7a7b7504b846b2e774dc5a25d2bb 553 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 411 423 7.2E-32 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 VMUT_2047 876f7a7b7504b846b2e774dc5a25d2bb 553 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 41 57 7.2E-32 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 VMUT_2047 876f7a7b7504b846b2e774dc5a25d2bb 553 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 63 81 7.2E-32 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 VMUT_2047 876f7a7b7504b846b2e774dc5a25d2bb 553 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 93 112 7.2E-32 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 VMUT_2047 876f7a7b7504b846b2e774dc5a25d2bb 553 SUPERFAMILY SSF54849 152 408 4.58E-25 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily VMUT_2047 876f7a7b7504b846b2e774dc5a25d2bb 553 Gene3D G3DSA:1.10.560.10 32 525 8.8E-198 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily VMUT_2047 876f7a7b7504b846b2e774dc5a25d2bb 553 Gene3D G3DSA:3.30.260.10 150 408 8.8E-198 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily VMUT_2047 876f7a7b7504b846b2e774dc5a25d2bb 553 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 93 101 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 VMUT_1454 30b608d24d95ec6145770460cec3fd58 803 SUPERFAMILY SSF52540 2 791 1.43E-32 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1454 30b608d24d95ec6145770460cec3fd58 803 SUPERFAMILY SSF75712 373 457 7.98E-11 T 23-10-2018 VMUT_1454 30b608d24d95ec6145770460cec3fd58 803 Pfam PF04423 Rad50 zinc hook motif 390 435 1.1E-5 T 23-10-2018 IPR013134 RAD50, zinc hook Reactome: R-HSA-2559586|Reactome: R-HSA-5685938|Reactome: R-HSA-5685939|Reactome: R-HSA-5685942|Reactome: R-HSA-5693548|Reactome: R-HSA-5693554|Reactome: R-HSA-5693565|Reactome: R-HSA-5693568|Reactome: R-HSA-5693571|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 VMUT_1454 30b608d24d95ec6145770460cec3fd58 803 Pfam PF02463 RecF/RecN/SMC N terminal domain 333 793 2.0E-12 T 23-10-2018 IPR003395 RecF/RecN/SMC, N-terminal VMUT_1454 30b608d24d95ec6145770460cec3fd58 803 SMART SM00382 21 793 7.1E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_1454 30b608d24d95ec6145770460cec3fd58 803 Gene3D G3DSA:1.10.287.510 361 478 2.3E-6 T 23-10-2018 VMUT_1454 30b608d24d95ec6145770460cec3fd58 803 Gene3D G3DSA:3.40.50.300 563 799 1.2E-34 T 23-10-2018 VMUT_1454 30b608d24d95ec6145770460cec3fd58 803 Gene3D G3DSA:3.40.50.300 1 293 3.7E-35 T 23-10-2018 VMUT_1454 30b608d24d95ec6145770460cec3fd58 803 Pfam PF13476 AAA domain 4 281 2.8E-20 T 23-10-2018 IPR038729 Rad50/SbcC-type AAA domain VMUT_1538 857506d8834b049a8d1c95283cd30f6c 285 SUPERFAMILY SSF56059 88 280 5.79E-45 T 23-10-2018 VMUT_1538 857506d8834b049a8d1c95283cd30f6c 285 Gene3D G3DSA:3.40.50.20 6 104 3.3E-18 T 23-10-2018 VMUT_1538 857506d8834b049a8d1c95283cd30f6c 285 Gene3D G3DSA:3.30.470.80 174 284 4.8E-40 T 23-10-2018 VMUT_1538 857506d8834b049a8d1c95283cd30f6c 285 Gene3D G3DSA:3.30.1490.20 105 173 3.1E-19 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VMUT_1538 857506d8834b049a8d1c95283cd30f6c 285 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 8 277 8.4E-78 T 23-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 VMUT_1538 857506d8834b049a8d1c95283cd30f6c 285 TIGRFAM TIGR02144 LysX_arch: lysine biosynthesis enzyme LysX 8 284 5.7E-97 T 23-10-2018 IPR011870 Lysine biosynthesis enzyme LysX GO:0003824|GO:0005524|GO:0009085 VMUT_1538 857506d8834b049a8d1c95283cd30f6c 285 SUPERFAMILY SSF52440 7 89 1.21E-13 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily VMUT_1538 857506d8834b049a8d1c95283cd30f6c 285 Pfam PF08443 RimK-like ATP-grasp domain 88 277 1.2E-34 T 23-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 VMUT_1588 ffd08b908b1f1d643c9c9bd1caa8ffb8 610 SUPERFAMILY SSF68923 3 233 5.75E-62 T 23-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 VMUT_1588 ffd08b908b1f1d643c9c9bd1caa8ffb8 610 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 234 593 9.4E-109 T 23-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 VMUT_1588 ffd08b908b1f1d643c9c9bd1caa8ffb8 610 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 8 594 35.368 T 23-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 VMUT_1588 ffd08b908b1f1d643c9c9bd1caa8ffb8 610 Gene3D G3DSA:3.40.449.10 17 236 3.6E-156 T 23-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 VMUT_1588 ffd08b908b1f1d643c9c9bd1caa8ffb8 610 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 19 229 5.5E-62 T 23-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 VMUT_1588 ffd08b908b1f1d643c9c9bd1caa8ffb8 610 PIRSF PIRSF001348 1 597 9.9E-197 T 23-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 VMUT_1588 ffd08b908b1f1d643c9c9bd1caa8ffb8 610 SUPERFAMILY SSF53795 234 593 1.22E-111 T 23-10-2018 VMUT_1588 ffd08b908b1f1d643c9c9bd1caa8ffb8 610 Gene3D G3DSA:2.170.8.10 55 387 3.6E-156 T 23-10-2018 VMUT_1588 ffd08b908b1f1d643c9c9bd1caa8ffb8 610 Gene3D G3DSA:3.90.228.20 237 592 3.6E-156 T 23-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 VMUT_1392 b5e97f927e75574fc9379b538b8e3588 540 SMART SM00487 2 218 1.3E-9 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain VMUT_1392 b5e97f927e75574fc9379b538b8e3588 540 Gene3D G3DSA:3.40.50.300 3 202 2.8E-13 T 23-10-2018 VMUT_1392 b5e97f927e75574fc9379b538b8e3588 540 SUPERFAMILY SSF52540 12 359 5.27E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1392 b5e97f927e75574fc9379b538b8e3588 540 Gene3D G3DSA:3.40.50.300 210 403 5.9E-21 T 23-10-2018 VMUT_1392 b5e97f927e75574fc9379b538b8e3588 540 Pfam PF00270 DEAD/DEAH box helicase 9 189 4.5E-8 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 VMUT_1392 b5e97f927e75574fc9379b538b8e3588 540 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 21 372 6.0E-51 T 23-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core VMUT_1392 b5e97f927e75574fc9379b538b8e3588 540 Pfam PF00271 Helicase conserved C-terminal domain 244 346 2.4E-13 T 23-10-2018 IPR001650 Helicase, C-terminal VMUT_1392 b5e97f927e75574fc9379b538b8e3588 540 SMART SM00490 269 347 9.8E-14 T 23-10-2018 IPR001650 Helicase, C-terminal VMUT_1568 db517658b2265d47e85aa68943b84af1 414 Pfam PF03144 Elongation factor Tu domain 2 235 302 1.5E-7 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 VMUT_1568 db517658b2265d47e85aa68943b84af1 414 Pfam PF09173 Initiation factor eIF2 gamma, C terminal 344 405 1.6E-15 T 23-10-2018 IPR015256 Translation initiation factor 2, gamma subunit, C-terminal VMUT_1568 db517658b2265d47e85aa68943b84af1 414 PRINTS PR00315 GTP-binding elongation factor signature 91 101 4.7E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VMUT_1568 db517658b2265d47e85aa68943b84af1 414 PRINTS PR00315 GTP-binding elongation factor signature 10 23 4.7E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VMUT_1568 db517658b2265d47e85aa68943b84af1 414 PRINTS PR00315 GTP-binding elongation factor signature 107 118 4.7E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VMUT_1568 db517658b2265d47e85aa68943b84af1 414 PRINTS PR00315 GTP-binding elongation factor signature 145 154 4.7E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VMUT_1568 db517658b2265d47e85aa68943b84af1 414 SUPERFAMILY SSF50447 211 316 1.64E-32 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VMUT_1568 db517658b2265d47e85aa68943b84af1 414 Gene3D G3DSA:3.40.50.300 9 207 6.0E-50 T 23-10-2018 VMUT_1568 db517658b2265d47e85aa68943b84af1 414 SUPERFAMILY SSF50465 317 407 3.64E-18 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal VMUT_1568 db517658b2265d47e85aa68943b84af1 414 SUPERFAMILY SSF52540 2 205 1.37E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1568 db517658b2265d47e85aa68943b84af1 414 Gene3D G3DSA:2.40.30.10 319 413 6.0E-16 T 23-10-2018 VMUT_1568 db517658b2265d47e85aa68943b84af1 414 Gene3D G3DSA:2.40.30.10 210 318 4.3E-40 T 23-10-2018 VMUT_1568 db517658b2265d47e85aa68943b84af1 414 Pfam PF00009 Elongation factor Tu GTP binding domain 11 204 3.0E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VMUT_0548 d2cc2357ad413214c61d89a1aca06467 562 SMART SM00729 240 486 3.2E-7 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VMUT_0548 d2cc2357ad413214c61d89a1aca06467 562 SUPERFAMILY SSF102114 227 454 2.35E-17 T 23-10-2018 VMUT_0548 d2cc2357ad413214c61d89a1aca06467 562 Pfam PF04055 Radical SAM superfamily 244 434 4.6E-13 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_0548 d2cc2357ad413214c61d89a1aca06467 562 Gene3D G3DSA:3.80.30.20 241 453 3.5E-20 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe VMUT_1079 4d539812ef10fbcf72455fe6c8405a62 182 Gene3D G3DSA:3.90.550.10 1 150 5.7E-15 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1079 4d539812ef10fbcf72455fe6c8405a62 182 Pfam PF00535 Glycosyl transferase family 2 5 106 3.8E-9 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VMUT_1079 4d539812ef10fbcf72455fe6c8405a62 182 SUPERFAMILY SSF53448 2 120 1.53E-16 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0840 dc85c75967ebcc71c6f95d0e7e6bd867 342 Gene3D G3DSA:3.90.180.10 1 340 1.1E-86 T 23-10-2018 VMUT_0840 dc85c75967ebcc71c6f95d0e7e6bd867 342 Pfam PF00107 Zinc-binding dehydrogenase 179 302 2.5E-20 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 VMUT_0840 dc85c75967ebcc71c6f95d0e7e6bd867 342 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 136 6.4E-21 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VMUT_0840 dc85c75967ebcc71c6f95d0e7e6bd867 342 SUPERFAMILY SSF51735 145 311 2.75E-33 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0840 dc85c75967ebcc71c6f95d0e7e6bd867 342 SMART SM00829 10 337 6.9E-10 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VMUT_0840 dc85c75967ebcc71c6f95d0e7e6bd867 342 SUPERFAMILY SSF50129 1 173 1.0E-44 T 23-10-2018 IPR011032 GroES-like superfamily VMUT_1158 4efad642ae81311fb1ef2a28fee48ded 383 Pfam PF00083 Sugar (and other) transporter 4 162 1.1E-14 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VMUT_1158 4efad642ae81311fb1ef2a28fee48ded 383 Pfam PF00083 Sugar (and other) transporter 221 382 3.9E-5 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VMUT_1158 4efad642ae81311fb1ef2a28fee48ded 383 SUPERFAMILY SSF103473 4 382 1.11E-44 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_1158 4efad642ae81311fb1ef2a28fee48ded 383 Gene3D G3DSA:1.20.1250.20 2 383 1.9E-46 T 23-10-2018 VMUT_1132 a72d55270d99dfee17b0d9cac22cde43 503 Pfam PF13353 4Fe-4S single cluster domain 142 243 2.8E-7 T 23-10-2018 VMUT_1132 a72d55270d99dfee17b0d9cac22cde43 503 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 391 476 1.2E-11 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain VMUT_1132 a72d55270d99dfee17b0d9cac22cde43 503 Gene3D G3DSA:3.20.20.70 137 437 2.8E-56 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_1132 a72d55270d99dfee17b0d9cac22cde43 503 SUPERFAMILY SSF102114 135 457 1.57E-76 T 23-10-2018 VMUT_1132 a72d55270d99dfee17b0d9cac22cde43 503 SMART SM00729 136 339 4.7E-9 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VMUT_1132 a72d55270d99dfee17b0d9cac22cde43 503 Pfam PF04055 Radical SAM superfamily 141 297 9.6E-24 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_1132 a72d55270d99dfee17b0d9cac22cde43 503 Pfam PF13186 Iron-sulfur cluster-binding domain 391 450 4.7E-10 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain VMUT_0981 5229db9123ae1e3123371caa59be0826 781 Pfam PF01433 Peptidase family M1 domain 196 419 1.8E-85 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 VMUT_0981 5229db9123ae1e3123371caa59be0826 781 Gene3D G3DSA:2.60.40.1730 5 176 9.2E-37 T 23-10-2018 VMUT_0981 5229db9123ae1e3123371caa59be0826 781 Gene3D G3DSA:1.10.390.60 181 424 2.6E-97 T 23-10-2018 VMUT_0981 5229db9123ae1e3123371caa59be0826 781 Gene3D G3DSA:1.25.50.20 506 769 4.7E-12 T 23-10-2018 VMUT_0981 5229db9123ae1e3123371caa59be0826 781 SUPERFAMILY SSF55486 195 431 8.64E-89 T 23-10-2018 VMUT_0981 5229db9123ae1e3123371caa59be0826 781 Pfam PF11838 ERAP1-like C-terminal domain 486 771 1.3E-26 T 23-10-2018 IPR024571 ERAP1-like C-terminal domain VMUT_0981 5229db9123ae1e3123371caa59be0826 781 Gene3D G3DSA:2.60.40.1910 425 499 5.2E-18 T 23-10-2018 VMUT_0981 5229db9123ae1e3123371caa59be0826 781 SUPERFAMILY SSF63737 5 174 5.89E-40 T 23-10-2018 VMUT_0981 5229db9123ae1e3123371caa59be0826 781 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 158 173 2.8E-26 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 VMUT_0981 5229db9123ae1e3123371caa59be0826 781 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 236 246 2.8E-26 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 VMUT_0981 5229db9123ae1e3123371caa59be0826 781 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 111 126 2.8E-26 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 VMUT_0981 5229db9123ae1e3123371caa59be0826 781 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 271 286 2.8E-26 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 VMUT_0981 5229db9123ae1e3123371caa59be0826 781 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 290 302 2.8E-26 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 VMUT_1548 946c49bc0f25e8081418950307e72c39 369 Pfam PF05193 Peptidase M16 inactive domain 195 306 6.4E-10 T 23-10-2018 IPR007863 Peptidase M16, C-terminal VMUT_1548 946c49bc0f25e8081418950307e72c39 369 SUPERFAMILY SSF63411 7 159 1.12E-11 T 23-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 VMUT_1548 946c49bc0f25e8081418950307e72c39 369 SUPERFAMILY SSF63411 203 368 2.17E-26 T 23-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 VMUT_1548 946c49bc0f25e8081418950307e72c39 369 Gene3D G3DSA:3.30.830.10 4 172 3.2E-9 T 23-10-2018 VMUT_1548 946c49bc0f25e8081418950307e72c39 369 Gene3D G3DSA:3.30.830.10 195 369 6.0E-28 T 23-10-2018 VMUT_1637 65b3e106d29e370cad4547e15a1276fb 304 SUPERFAMILY SSF55347 152 277 7.06E-8 T 23-10-2018 VMUT_1637 65b3e106d29e370cad4547e15a1276fb 304 Gene3D G3DSA:3.40.50.720 1 119 5.5E-15 T 23-10-2018 VMUT_1637 65b3e106d29e370cad4547e15a1276fb 304 SUPERFAMILY SSF51735 1 178 1.56E-24 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1637 65b3e106d29e370cad4547e15a1276fb 304 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 120 2.8E-15 T 23-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 VMUT_1637 65b3e106d29e370cad4547e15a1276fb 304 Gene3D G3DSA:3.30.360.10 122 293 2.0E-20 T 23-10-2018 VMUT_0409 ddb0547700abdef91cf0c941f4f46ae2 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 280 9.3E-16 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VMUT_0409 ddb0547700abdef91cf0c941f4f46ae2 290 SUPERFAMILY SSF161098 15 289 9.25E-53 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_0409 ddb0547700abdef91cf0c941f4f46ae2 290 Gene3D G3DSA:1.10.3720.10 9 277 1.8E-49 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_0654 44df5f238279c41bb30f00de77a76f60 338 Gene3D G3DSA:3.40.50.300 1 162 6.6E-59 T 23-10-2018 VMUT_0654 44df5f238279c41bb30f00de77a76f60 338 Gene3D G3DSA:1.20.272.10 227 322 2.2E-30 T 23-10-2018 VMUT_0654 44df5f238279c41bb30f00de77a76f60 338 Pfam PF08542 Replication factor C C-terminal domain 228 315 2.3E-21 T 23-10-2018 IPR013748 Replication factor C, C-terminal Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-176187|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804756|Reactome: R-HSA-69091|Reactome: R-HSA-69473 VMUT_0654 44df5f238279c41bb30f00de77a76f60 338 Gene3D G3DSA:1.10.8.60 163 226 1.6E-22 T 23-10-2018 VMUT_0654 44df5f238279c41bb30f00de77a76f60 338 SMART SM00382 38 163 1.5E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0654 44df5f238279c41bb30f00de77a76f60 338 SUPERFAMILY SSF48019 227 319 2.01E-18 T 23-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 VMUT_0654 44df5f238279c41bb30f00de77a76f60 338 Hamap MF_01509 Replication factor C small subunit [rfcS]. 4 320 48.178 T 23-10-2018 IPR023748 Replication factor C small subunit, archaeal GO:0003689|GO:0005524|GO:0005663|GO:0006260 VMUT_0654 44df5f238279c41bb30f00de77a76f60 338 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 42 159 1.9E-17 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VMUT_0654 44df5f238279c41bb30f00de77a76f60 338 SUPERFAMILY SSF52540 6 224 5.06E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0613 be7d6cdced0b35829c001622eeed1543 461 Gene3D G3DSA:1.20.1250.20 255 461 2.3E-12 T 23-10-2018 VMUT_0613 be7d6cdced0b35829c001622eeed1543 461 ProSitePatterns PS00216 Sugar transport proteins signature 1. 80 96 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VMUT_0613 be7d6cdced0b35829c001622eeed1543 461 SUPERFAMILY SSF103473 26 450 1.03E-39 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_0613 be7d6cdced0b35829c001622eeed1543 461 Pfam PF00083 Sugar (and other) transporter 71 436 1.5E-21 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VMUT_0613 be7d6cdced0b35829c001622eeed1543 461 Gene3D G3DSA:1.20.1250.20 21 238 8.2E-27 T 23-10-2018 VMUT_1967 53fe234f372270b64f3459c4150146d2 367 Gene3D G3DSA:2.40.50.140 286 350 3.2E-13 T 23-10-2018 VMUT_1967 53fe234f372270b64f3459c4150146d2 367 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VMUT_1967 53fe234f372270b64f3459c4150146d2 367 SUPERFAMILY SSF50331 243 359 1.56E-19 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal VMUT_1967 53fe234f372270b64f3459c4150146d2 367 Gene3D G3DSA:2.40.50.100 245 363 3.2E-13 T 23-10-2018 VMUT_1967 53fe234f372270b64f3459c4150146d2 367 Gene3D G3DSA:3.40.50.300 1 244 2.0E-71 T 23-10-2018 VMUT_1967 53fe234f372270b64f3459c4150146d2 367 Pfam PF08402 TOBE domain 283 357 2.2E-5 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 VMUT_1967 53fe234f372270b64f3459c4150146d2 367 SMART SM00382 29 226 2.4E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_1967 53fe234f372270b64f3459c4150146d2 367 SUPERFAMILY SSF52540 5 248 5.17E-83 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1967 53fe234f372270b64f3459c4150146d2 367 Pfam PF00005 ABC transporter 20 168 5.7E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_0883 f6cead14a5f49307d41a56ee885f74ce 885 ProSitePatterns PS00674 AAA-protein family signature. 482 500 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 VMUT_0883 f6cead14a5f49307d41a56ee885f74ce 885 SMART SM00382 376 514 4.9E-20 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0883 f6cead14a5f49307d41a56ee885f74ce 885 SMART SM00382 653 789 1.1E-21 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0883 f6cead14a5f49307d41a56ee885f74ce 885 Gene3D G3DSA:1.10.8.60 788 862 2.0E-81 T 23-10-2018 VMUT_0883 f6cead14a5f49307d41a56ee885f74ce 885 Gene3D G3DSA:1.10.8.60 513 582 8.3E-77 T 23-10-2018 VMUT_0883 f6cead14a5f49307d41a56ee885f74ce 885 Gene3D G3DSA:3.40.50.300 341 597 8.3E-77 T 23-10-2018 VMUT_0883 f6cead14a5f49307d41a56ee885f74ce 885 SUPERFAMILY SSF52540 342 597 2.21E-65 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0883 f6cead14a5f49307d41a56ee885f74ce 885 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 380 511 1.8E-41 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VMUT_0883 f6cead14a5f49307d41a56ee885f74ce 885 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 657 786 1.3E-36 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VMUT_0883 f6cead14a5f49307d41a56ee885f74ce 885 SUPERFAMILY SSF52540 615 877 2.01E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0883 f6cead14a5f49307d41a56ee885f74ce 885 ProSitePatterns PS00674 AAA-protein family signature. 757 775 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 VMUT_0883 f6cead14a5f49307d41a56ee885f74ce 885 Gene3D G3DSA:3.40.50.300 615 877 2.0E-81 T 23-10-2018 VMUT_1306 8036777694594cf3d44f487c2d69042b 243 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 150 166 1.5E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VMUT_1306 8036777694594cf3d44f487c2d69042b 243 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 9 20 1.5E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VMUT_1306 8036777694594cf3d44f487c2d69042b 243 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 116 129 1.5E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VMUT_1306 8036777694594cf3d44f487c2d69042b 243 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 168 188 1.5E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VMUT_1306 8036777694594cf3d44f487c2d69042b 243 Pfam PF13419 Haloacid dehalogenase-like hydrolase 12 204 1.5E-21 T 23-10-2018 VMUT_1306 8036777694594cf3d44f487c2d69042b 243 Gene3D G3DSA:3.40.50.1000 10 236 6.5E-39 T 23-10-2018 IPR023214 HAD superfamily VMUT_1306 8036777694594cf3d44f487c2d69042b 243 SUPERFAMILY SSF56784 8 241 7.11E-39 T 23-10-2018 IPR036412 HAD-like superfamily VMUT_1306 8036777694594cf3d44f487c2d69042b 243 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 105 201 1.9E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VMUT_1306 8036777694594cf3d44f487c2d69042b 243 Gene3D G3DSA:1.20.120.710 22 103 6.5E-39 T 23-10-2018 VMUT_0419 be5edffa36154151f7ae494bbbd71fce 748 Gene3D G3DSA:3.40.50.300 465 735 2.0E-102 T 23-10-2018 VMUT_0419 be5edffa36154151f7ae494bbbd71fce 748 ProSitePatterns PS00674 AAA-protein family signature. 318 336 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 VMUT_0419 be5edffa36154151f7ae494bbbd71fce 748 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 112 169 8.3E-8 T 23-10-2018 IPR004201 CDC48, domain 2 VMUT_0419 be5edffa36154151f7ae494bbbd71fce 748 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 218 347 6.6E-50 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VMUT_0419 be5edffa36154151f7ae494bbbd71fce 748 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 507 637 3.6E-46 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VMUT_0419 be5edffa36154151f7ae494bbbd71fce 748 SMART SM01072 109 170 7.5E-10 T 23-10-2018 IPR004201 CDC48, domain 2 VMUT_0419 be5edffa36154151f7ae494bbbd71fce 748 SUPERFAMILY SSF52540 465 736 9.85E-75 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0419 be5edffa36154151f7ae494bbbd71fce 748 Gene3D G3DSA:1.10.8.60 639 722 2.0E-102 T 23-10-2018 VMUT_0419 be5edffa36154151f7ae494bbbd71fce 748 SMART SM00382 214 350 3.8E-22 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0419 be5edffa36154151f7ae494bbbd71fce 748 SMART SM00382 503 640 4.6E-23 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0419 be5edffa36154151f7ae494bbbd71fce 748 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 9 92 2.1E-30 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain VMUT_0419 be5edffa36154151f7ae494bbbd71fce 748 SMART SM01073 8 93 4.9E-36 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain VMUT_0419 be5edffa36154151f7ae494bbbd71fce 748 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 7 744 0.0 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 VMUT_0419 be5edffa36154151f7ae494bbbd71fce 748 ProSitePatterns PS00674 AAA-protein family signature. 608 626 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 VMUT_0419 be5edffa36154151f7ae494bbbd71fce 748 Gene3D G3DSA:3.40.50.300 173 348 9.5E-73 T 23-10-2018 VMUT_0419 be5edffa36154151f7ae494bbbd71fce 748 SUPERFAMILY SSF50692 3 91 1.62E-26 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily VMUT_0419 be5edffa36154151f7ae494bbbd71fce 748 SUPERFAMILY SSF52540 175 456 4.6E-70 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0419 be5edffa36154151f7ae494bbbd71fce 748 SUPERFAMILY SSF54585 94 183 3.92E-15 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily VMUT_0419 be5edffa36154151f7ae494bbbd71fce 748 Gene3D G3DSA:1.10.8.60 349 459 6.9E-26 T 23-10-2018 VMUT_0419 be5edffa36154151f7ae494bbbd71fce 748 Gene3D G3DSA:2.40.40.20 1 92 5.3E-33 T 23-10-2018 VMUT_1333 4cdbb91723847da61d15757937cf95fa 146 Gene3D G3DSA:1.10.10.10 15 114 2.4E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_1333 4cdbb91723847da61d15757937cf95fa 146 SUPERFAMILY SSF46785 8 94 6.61E-24 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_1333 4cdbb91723847da61d15757937cf95fa 146 Pfam PF03551 Transcriptional regulator PadR-like family 25 92 4.0E-19 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal VMUT_1094 b298ea9e1db063ba959f511d89cd58ca 261 Pfam PF00535 Glycosyl transferase family 2 54 179 8.3E-16 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VMUT_1094 b298ea9e1db063ba959f511d89cd58ca 261 Gene3D G3DSA:3.90.550.10 25 247 3.6E-26 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1094 b298ea9e1db063ba959f511d89cd58ca 261 SUPERFAMILY SSF53448 46 229 6.19E-31 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1559 8ff710ef1e418f51b86555518d99aa13 272 SMART SM01092 167 269 1.0E-33 T 23-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal VMUT_1559 8ff710ef1e418f51b86555518d99aa13 272 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 1 160 1.9E-47 T 23-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 VMUT_1559 8ff710ef1e418f51b86555518d99aa13 272 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 168 268 3.8E-27 T 23-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal VMUT_1559 8ff710ef1e418f51b86555518d99aa13 272 SUPERFAMILY SSF56176 1 160 1.31E-51 T 23-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VMUT_1559 8ff710ef1e418f51b86555518d99aa13 272 Gene3D G3DSA:3.30.465.10 44 160 1.6E-38 T 23-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 VMUT_1559 8ff710ef1e418f51b86555518d99aa13 272 Gene3D G3DSA:3.30.390.50 166 272 6.7E-39 T 23-10-2018 VMUT_1559 8ff710ef1e418f51b86555518d99aa13 272 SUPERFAMILY SSF55447 166 271 1.57E-31 T 23-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily VMUT_1559 8ff710ef1e418f51b86555518d99aa13 272 Gene3D G3DSA:3.30.43.10 1 43 1.5E-18 T 23-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 VMUT_0339 06e13b35cdc3633e79d70d0b0fbcaa2b 213 SUPERFAMILY SSF111278 5 177 1.83E-42 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 VMUT_0339 06e13b35cdc3633e79d70d0b0fbcaa2b 213 Pfam PF02676 Methyltransferase TYW3 6 174 1.1E-32 T 23-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 VMUT_0339 06e13b35cdc3633e79d70d0b0fbcaa2b 213 Gene3D G3DSA:3.30.1960.10 1 178 2.2E-50 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 VMUT_0339 06e13b35cdc3633e79d70d0b0fbcaa2b 213 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 2 180 26.162 T 23-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 VMUT_1605 c408fb95b1bb19234a61c54668815dac 311 SUPERFAMILY SSF47954 219 309 1.02E-17 T 23-10-2018 IPR036915 Cyclin-like superfamily VMUT_1605 c408fb95b1bb19234a61c54668815dac 311 Gene3D G3DSA:1.10.472.170 13 203 9.7E-34 T 23-10-2018 VMUT_1605 c408fb95b1bb19234a61c54668815dac 311 SMART SM00385 218 303 1.5E-5 T 23-10-2018 IPR013763 Cyclin-like VMUT_1605 c408fb95b1bb19234a61c54668815dac 311 Pfam PF08271 TFIIB zinc-binding 14 55 9.2E-19 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type VMUT_1605 c408fb95b1bb19234a61c54668815dac 311 Pfam PF00382 Transcription factor TFIIB repeat 221 294 6.9E-8 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 VMUT_1605 c408fb95b1bb19234a61c54668815dac 311 SUPERFAMILY SSF57783 7 58 6.23E-18 T 23-10-2018 VMUT_1605 c408fb95b1bb19234a61c54668815dac 311 SUPERFAMILY SSF47954 92 185 2.01E-8 T 23-10-2018 IPR036915 Cyclin-like superfamily VMUT_1605 c408fb95b1bb19234a61c54668815dac 311 Gene3D G3DSA:1.10.472.10 217 310 4.0E-16 T 23-10-2018 VMUT_1605 c408fb95b1bb19234a61c54668815dac 311 PRINTS PR00685 Transcription initiation factor IIB signature 27 47 7.5E-22 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 VMUT_1605 c408fb95b1bb19234a61c54668815dac 311 PRINTS PR00685 Transcription initiation factor IIB signature 188 203 7.5E-22 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 VMUT_1605 c408fb95b1bb19234a61c54668815dac 311 PRINTS PR00685 Transcription initiation factor IIB signature 289 303 7.5E-22 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 VMUT_1605 c408fb95b1bb19234a61c54668815dac 311 PRINTS PR00685 Transcription initiation factor IIB signature 49 62 7.5E-22 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 VMUT_1605 c408fb95b1bb19234a61c54668815dac 311 PRINTS PR00685 Transcription initiation factor IIB signature 161 180 7.5E-22 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 VMUT_1605 c408fb95b1bb19234a61c54668815dac 311 PRINTS PR00685 Transcription initiation factor IIB signature 257 273 7.5E-22 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 VMUT_0365 89e6be0bcee514fcdcf46a68af311afe 145 Pfam PF01092 Ribosomal protein S6e 1 113 2.5E-26 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0365 89e6be0bcee514fcdcf46a68af311afe 145 ProSitePatterns PS00578 Ribosomal protein S6e signature. 51 62 - T 23-10-2018 IPR018282 Ribosomal protein S6e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0365 89e6be0bcee514fcdcf46a68af311afe 145 SMART SM01405 1 135 1.9E-40 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0365 89e6be0bcee514fcdcf46a68af311afe 145 Hamap MF_00512 30S ribosomal protein S6e [rps6e]. 1 113 12.298 T 23-10-2018 IPR020924 Ribosomal protein S6e, archaeal GO:0003735|GO:0005840|GO:0006412 VMUT_2142 92b37e6b80bdacaf4869dd3a4b7de25f 461 Gene3D G3DSA:3.90.1150.10 25 448 6.9E-154 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VMUT_2142 92b37e6b80bdacaf4869dd3a4b7de25f 461 Gene3D G3DSA:3.40.640.10 81 351 6.9E-154 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VMUT_2142 92b37e6b80bdacaf4869dd3a4b7de25f 461 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 270 307 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VMUT_2142 92b37e6b80bdacaf4869dd3a4b7de25f 461 Pfam PF00202 Aminotransferase class-III 46 452 3.1E-119 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VMUT_2142 92b37e6b80bdacaf4869dd3a4b7de25f 461 PIRSF PIRSF000521 5 154 1.5E-9 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VMUT_2142 92b37e6b80bdacaf4869dd3a4b7de25f 461 PIRSF PIRSF000521 147 455 7.4E-47 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VMUT_2142 92b37e6b80bdacaf4869dd3a4b7de25f 461 SUPERFAMILY SSF53383 37 454 2.4E-127 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VMUT_1526 fee3cd8644e8a3320ff456780efc5c7a 174 Hamap MF_01032 Methanogen homoaconitase small subunit [hacB]. 13 173 34.953 T 23-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 VMUT_1526 fee3cd8644e8a3320ff456780efc5c7a 174 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 15 170 9.5E-66 T 23-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 VMUT_1526 fee3cd8644e8a3320ff456780efc5c7a 174 Gene3D G3DSA:3.20.19.10 10 173 1.7E-55 T 23-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 VMUT_1526 fee3cd8644e8a3320ff456780efc5c7a 174 Pfam PF00694 Aconitase C-terminal domain 56 113 1.7E-19 T 23-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 VMUT_1526 fee3cd8644e8a3320ff456780efc5c7a 174 SUPERFAMILY SSF52016 12 172 2.55E-45 T 23-10-2018 VMUT_0238 5aab2c6178429e5f1dc1f10d72138220 383 Pfam PF04055 Radical SAM superfamily 82 238 3.3E-16 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_0238 5aab2c6178429e5f1dc1f10d72138220 383 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 10 334 1.5E-98 T 23-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme VMUT_0238 5aab2c6178429e5f1dc1f10d72138220 383 SUPERFAMILY SSF102114 40 316 4.58E-31 T 23-10-2018 VMUT_0238 5aab2c6178429e5f1dc1f10d72138220 383 Gene3D G3DSA:3.20.20.70 68 287 2.2E-26 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_0324 b17471bf2e17884ac6dd1ab121eb1692 385 Pfam PF04055 Radical SAM superfamily 48 192 6.8E-23 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_0324 b17471bf2e17884ac6dd1ab121eb1692 385 PIRSF PIRSF037420 29 383 6.6E-65 T 23-10-2018 IPR017200 Coenzyme PQQ synthesis protein E VMUT_0324 b17471bf2e17884ac6dd1ab121eb1692 385 Pfam PF13353 4Fe-4S single cluster domain 46 152 9.6E-8 T 23-10-2018 VMUT_0324 b17471bf2e17884ac6dd1ab121eb1692 385 Gene3D G3DSA:3.20.20.70 38 339 3.4E-59 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_0324 b17471bf2e17884ac6dd1ab121eb1692 385 SMART SM00729 42 244 1.4E-4 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VMUT_0324 b17471bf2e17884ac6dd1ab121eb1692 385 Pfam PF13186 Iron-sulfur cluster-binding domain 285 347 1.6E-8 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain VMUT_0324 b17471bf2e17884ac6dd1ab121eb1692 385 SUPERFAMILY SSF102114 42 356 2.62E-62 T 23-10-2018 VMUT_0324 b17471bf2e17884ac6dd1ab121eb1692 385 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 285 374 2.3E-14 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain VMUT_2314 6de0fade109d2b1c0ac220b6f8a7a882 478 Gene3D G3DSA:1.20.1720.10 8 220 1.4E-40 T 23-10-2018 VMUT_2314 6de0fade109d2b1c0ac220b6f8a7a882 478 Gene3D G3DSA:1.20.1250.20 251 462 7.6E-17 T 23-10-2018 VMUT_2314 6de0fade109d2b1c0ac220b6f8a7a882 478 SUPERFAMILY SSF103473 196 463 3.27E-24 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_2314 6de0fade109d2b1c0ac220b6f8a7a882 478 Pfam PF07690 Major Facilitator Superfamily 13 184 7.4E-35 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_2314 6de0fade109d2b1c0ac220b6f8a7a882 478 Pfam PF07690 Major Facilitator Superfamily 196 403 1.3E-11 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_2314 6de0fade109d2b1c0ac220b6f8a7a882 478 SUPERFAMILY SSF103473 3 185 9.16E-41 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_0529 34d028b3b33090bba780734bcefb8c3a 338 Gene3D G3DSA:3.40.440.10 1 335 8.6E-106 T 23-10-2018 VMUT_0529 34d028b3b33090bba780734bcefb8c3a 338 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 315 328 - T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 VMUT_0529 34d028b3b33090bba780734bcefb8c3a 338 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 338 76.495 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 VMUT_0529 34d028b3b33090bba780734bcefb8c3a 338 SMART SM00788 3 330 5.4E-113 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 VMUT_0529 34d028b3b33090bba780734bcefb8c3a 338 SUPERFAMILY SSF52540 3 331 1.04E-87 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0529 34d028b3b33090bba780734bcefb8c3a 338 Pfam PF00709 Adenylosuccinate synthetase 288 329 4.8E-5 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 VMUT_0529 34d028b3b33090bba780734bcefb8c3a 338 Pfam PF00709 Adenylosuccinate synthetase 4 138 4.9E-27 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 VMUT_0529 34d028b3b33090bba780734bcefb8c3a 338 Pfam PF00709 Adenylosuccinate synthetase 146 284 6.7E-37 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 VMUT_0026 6c4942ffb30247c97b4b4aec81592d7c 198 Gene3D G3DSA:1.10.357.10 2 194 5.6E-33 T 23-10-2018 VMUT_0026 6c4942ffb30247c97b4b4aec81592d7c 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.3E-10 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VMUT_0026 6c4942ffb30247c97b4b4aec81592d7c 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.3E-10 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VMUT_0026 6c4942ffb30247c97b4b4aec81592d7c 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 2.8E-16 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VMUT_0026 6c4942ffb30247c97b4b4aec81592d7c 198 SUPERFAMILY SSF48498 93 181 8.26E-6 T 23-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VMUT_0026 6c4942ffb30247c97b4b4aec81592d7c 198 SUPERFAMILY SSF46689 4 83 1.85E-19 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VMUT_0026 6c4942ffb30247c97b4b4aec81592d7c 198 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 60 - T 23-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site VMUT_0344 b28ee5d245b17f61948fe6c5241608c2 591 Gene3D G3DSA:1.10.30.30 359 429 4.0E-124 T 23-10-2018 VMUT_0344 b28ee5d245b17f61948fe6c5241608c2 591 Gene3D G3DSA:1.20.1430.20 85 153 4.0E-124 T 23-10-2018 VMUT_0344 b28ee5d245b17f61948fe6c5241608c2 591 Pfam PF03129 Anticodon binding domain 478 567 2.5E-17 T 23-10-2018 IPR004154 Anticodon-binding VMUT_0344 b28ee5d245b17f61948fe6c5241608c2 591 Gene3D G3DSA:3.40.50.800 470 583 5.6E-29 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily VMUT_0344 b28ee5d245b17f61948fe6c5241608c2 591 SUPERFAMILY SSF52954 467 569 4.08E-28 T 23-10-2018 VMUT_0344 b28ee5d245b17f61948fe6c5241608c2 591 PRINTS PR01043 Glycyl-tRNA synthetase signature 148 160 6.5E-47 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 VMUT_0344 b28ee5d245b17f61948fe6c5241608c2 591 PRINTS PR01043 Glycyl-tRNA synthetase signature 438 450 6.5E-47 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 VMUT_0344 b28ee5d245b17f61948fe6c5241608c2 591 PRINTS PR01043 Glycyl-tRNA synthetase signature 25 39 6.5E-47 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 VMUT_0344 b28ee5d245b17f61948fe6c5241608c2 591 PRINTS PR01043 Glycyl-tRNA synthetase signature 216 226 6.5E-47 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 VMUT_0344 b28ee5d245b17f61948fe6c5241608c2 591 PRINTS PR01043 Glycyl-tRNA synthetase signature 167 184 6.5E-47 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 VMUT_0344 b28ee5d245b17f61948fe6c5241608c2 591 PRINTS PR01043 Glycyl-tRNA synthetase signature 516 535 6.5E-47 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 VMUT_0344 b28ee5d245b17f61948fe6c5241608c2 591 PRINTS PR01043 Glycyl-tRNA synthetase signature 199 216 6.5E-47 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 VMUT_0344 b28ee5d245b17f61948fe6c5241608c2 591 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 2 568 2.6E-171 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 VMUT_0344 b28ee5d245b17f61948fe6c5241608c2 591 Gene3D G3DSA:3.30.930.10 13 460 4.0E-124 T 23-10-2018 VMUT_0344 b28ee5d245b17f61948fe6c5241608c2 591 SUPERFAMILY SSF55681 3 481 4.15E-104 T 23-10-2018 VMUT_0107 44e86cfa911db2181dbe848f12b9eb63 380 SUPERFAMILY SSF51905 5 313 5.46E-40 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0107 44e86cfa911db2181dbe848f12b9eb63 380 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 140 155 9.8E-12 T 23-10-2018 VMUT_0107 44e86cfa911db2181dbe848f12b9eb63 380 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 9.8E-12 T 23-10-2018 VMUT_0107 44e86cfa911db2181dbe848f12b9eb63 380 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 250 265 9.8E-12 T 23-10-2018 VMUT_0107 44e86cfa911db2181dbe848f12b9eb63 380 Pfam PF01494 FAD binding domain 5 166 5.5E-14 T 23-10-2018 IPR002938 FAD-binding domain GO:0071949 VMUT_0107 44e86cfa911db2181dbe848f12b9eb63 380 Gene3D G3DSA:3.50.50.60 3 347 1.7E-67 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0107 44e86cfa911db2181dbe848f12b9eb63 380 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 5 283 4.6E-63 T 23-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 VMUT_0150 0347e412a755c7b906ea1fc797ca2130 254 Pfam PF06745 KaiC 8 239 1.7E-63 T 23-10-2018 IPR014774 KaiC-like domain VMUT_0150 0347e412a755c7b906ea1fc797ca2130 254 Gene3D G3DSA:3.40.50.300 5 240 2.9E-47 T 23-10-2018 VMUT_0150 0347e412a755c7b906ea1fc797ca2130 254 SUPERFAMILY SSF52540 7 240 2.0E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0150 0347e412a755c7b906ea1fc797ca2130 254 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 29 42 - T 23-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 VMUT_0150 0347e412a755c7b906ea1fc797ca2130 254 PRINTS PR01874 DNA repair protein radA signature 17 45 9.1E-9 T 23-10-2018 VMUT_0150 0347e412a755c7b906ea1fc797ca2130 254 PRINTS PR01874 DNA repair protein radA signature 60 77 9.1E-9 T 23-10-2018 VMUT_0305 2c9836577500c16c7a64a04c44006f77 584 PRINTS PR01041 Methionyl-tRNA synthetase signature 397 408 3.7E-21 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 VMUT_0305 2c9836577500c16c7a64a04c44006f77 584 PRINTS PR01041 Methionyl-tRNA synthetase signature 303 318 3.7E-21 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 VMUT_0305 2c9836577500c16c7a64a04c44006f77 584 PRINTS PR01041 Methionyl-tRNA synthetase signature 52 66 3.7E-21 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 VMUT_0305 2c9836577500c16c7a64a04c44006f77 584 PRINTS PR01041 Methionyl-tRNA synthetase signature 263 274 3.7E-21 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 VMUT_0305 2c9836577500c16c7a64a04c44006f77 584 PRINTS PR01041 Methionyl-tRNA synthetase signature 100 111 3.7E-21 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 VMUT_0305 2c9836577500c16c7a64a04c44006f77 584 PRINTS PR01041 Methionyl-tRNA synthetase signature 19 32 3.7E-21 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 VMUT_0305 2c9836577500c16c7a64a04c44006f77 584 SUPERFAMILY SSF57770 152 186 1.57E-11 T 23-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 VMUT_0305 2c9836577500c16c7a64a04c44006f77 584 Hamap MF_00098 Methionine--tRNA ligase [metG]. 15 561 37.752 T 23-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 VMUT_0305 2c9836577500c16c7a64a04c44006f77 584 SUPERFAMILY SSF52374 15 397 3.13E-92 T 23-10-2018 VMUT_0305 2c9836577500c16c7a64a04c44006f77 584 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 19 551 7.7E-149 T 23-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 VMUT_0305 2c9836577500c16c7a64a04c44006f77 584 SUPERFAMILY SSF47323 402 562 9.72E-35 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_0305 2c9836577500c16c7a64a04c44006f77 584 Gene3D G3DSA:2.20.28.20 152 186 2.0E-144 T 23-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 VMUT_0305 2c9836577500c16c7a64a04c44006f77 584 Gene3D G3DSA:3.40.50.620 18 393 2.0E-144 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_0305 2c9836577500c16c7a64a04c44006f77 584 Pfam PF09334 tRNA synthetases class I (M) 18 410 1.6E-149 T 23-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_0305 2c9836577500c16c7a64a04c44006f77 584 Gene3D G3DSA:1.10.730.10 394 556 2.7E-34 T 23-10-2018 VMUT_1241 88e0f3a4f374c8c662502eebceb4c1e4 335 SUPERFAMILY SSF51658 14 327 3.87E-54 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily VMUT_1241 88e0f3a4f374c8c662502eebceb4c1e4 335 PIRSF PIRSF016049 146 335 3.6E-66 T 23-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 VMUT_1241 88e0f3a4f374c8c662502eebceb4c1e4 335 PIRSF PIRSF016049 3 157 5.3E-25 T 23-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 VMUT_1241 88e0f3a4f374c8c662502eebceb4c1e4 335 Pfam PF03786 D-mannonate dehydratase (UxuA) 152 327 7.0E-63 T 23-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 VMUT_1241 88e0f3a4f374c8c662502eebceb4c1e4 335 Gene3D G3DSA:3.20.20.150 11 335 6.3E-91 T 23-10-2018 VMUT_0879 619025bc8f7ba258f7ae4b9a7983bf51 415 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 133 325 1.6E-17 T 23-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 VMUT_0879 619025bc8f7ba258f7ae4b9a7983bf51 415 Gene3D G3DSA:3.20.20.70 125 317 1.2E-59 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_0879 619025bc8f7ba258f7ae4b9a7983bf51 415 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 68 131 7.7E-6 T 23-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 VMUT_0879 619025bc8f7ba258f7ae4b9a7983bf51 415 SUPERFAMILY SSF54675 18 133 6.28E-29 T 23-10-2018 VMUT_0879 619025bc8f7ba258f7ae4b9a7983bf51 415 SUPERFAMILY SSF51690 130 411 2.5E-70 T 23-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 VMUT_0879 619025bc8f7ba258f7ae4b9a7983bf51 415 PIRSF PIRSF000484 83 414 7.5E-55 T 23-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 VMUT_0879 619025bc8f7ba258f7ae4b9a7983bf51 415 PIRSF PIRSF000484 23 86 10.0 T 23-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 VMUT_0879 619025bc8f7ba258f7ae4b9a7983bf51 415 Gene3D G3DSA:3.90.1170.20 12 124 2.5E-35 T 23-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 VMUT_0505 dc393cd8c2b66a055236eb09e3ecadfb 142 Pfam PF05168 HEPN domain 10 134 1.2E-22 T 23-10-2018 IPR007842 HEPN domain VMUT_0505 dc393cd8c2b66a055236eb09e3ecadfb 142 SUPERFAMILY SSF81593 12 138 1.26E-17 T 23-10-2018 VMUT_0505 dc393cd8c2b66a055236eb09e3ecadfb 142 SMART SM00748 13 130 1.5E-6 T 23-10-2018 IPR007842 HEPN domain VMUT_0505 dc393cd8c2b66a055236eb09e3ecadfb 142 Gene3D G3DSA:1.20.120.330 3 140 1.0E-24 T 23-10-2018 VMUT_1136 fcd74f5dbb454c97f7d17a6fca474aef 352 SUPERFAMILY SSF52402 24 205 1.81E-52 T 23-10-2018 VMUT_1136 fcd74f5dbb454c97f7d17a6fca474aef 352 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 229 310 1.8E-31 T 23-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 VMUT_1136 fcd74f5dbb454c97f7d17a6fca474aef 352 SUPERFAMILY SSF52467 226 347 1.66E-44 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily VMUT_1136 fcd74f5dbb454c97f7d17a6fca474aef 352 Pfam PF01012 Electron transfer flavoprotein domain 26 204 2.2E-44 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 VMUT_1136 fcd74f5dbb454c97f7d17a6fca474aef 352 Gene3D G3DSA:3.40.50.620 21 210 3.1E-67 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_1136 fcd74f5dbb454c97f7d17a6fca474aef 352 SMART SM00893 25 217 2.2E-44 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 VMUT_1136 fcd74f5dbb454c97f7d17a6fca474aef 352 PIRSF PIRSF000089 21 352 1.1E-109 T 23-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 VMUT_1136 fcd74f5dbb454c97f7d17a6fca474aef 352 Gene3D G3DSA:3.40.50.1220 221 352 7.7E-51 T 23-10-2018 VMUT_0538 060168d6ddb6fd379724d1ccd618727b 272 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VMUT_0538 060168d6ddb6fd379724d1ccd618727b 272 Gene3D G3DSA:3.40.50.720 4 267 6.9E-80 T 23-10-2018 VMUT_0538 060168d6ddb6fd379724d1ccd618727b 272 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 25 261 3.0E-65 T 23-10-2018 VMUT_0538 060168d6ddb6fd379724d1ccd618727b 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 1.9E-30 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0538 060168d6ddb6fd379724d1ccd618727b 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 1.9E-30 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0538 060168d6ddb6fd379724d1ccd618727b 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 158 1.9E-30 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0538 060168d6ddb6fd379724d1ccd618727b 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 1.9E-30 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0538 060168d6ddb6fd379724d1ccd618727b 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 1.9E-30 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0538 060168d6ddb6fd379724d1ccd618727b 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 1.9E-30 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0538 060168d6ddb6fd379724d1ccd618727b 272 SUPERFAMILY SSF51735 18 262 2.79E-78 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1560 77b85573d9d073191a88dd45bb38b11d 731 SUPERFAMILY SSF56003 111 728 6.41E-174 T 23-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 VMUT_1560 77b85573d9d073191a88dd45bb38b11d 731 SUPERFAMILY SSF54665 3 134 1.7E-41 T 23-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily VMUT_1560 77b85573d9d073191a88dd45bb38b11d 731 Gene3D G3DSA:3.90.1170.50 1 119 2.4E-40 T 23-10-2018 VMUT_1560 77b85573d9d073191a88dd45bb38b11d 731 Gene3D G3DSA:3.30.365.10 433 590 6.0E-108 T 23-10-2018 VMUT_1560 77b85573d9d073191a88dd45bb38b11d 731 Gene3D G3DSA:3.30.365.10 173 267 1.0E-59 T 23-10-2018 VMUT_1560 77b85573d9d073191a88dd45bb38b11d 731 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 18 119 1.9E-29 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead VMUT_1560 77b85573d9d073191a88dd45bb38b11d 731 SMART SM01008 18 119 5.4E-46 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead VMUT_1560 77b85573d9d073191a88dd45bb38b11d 731 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 143 672 2.2E-152 T 23-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 VMUT_1560 77b85573d9d073191a88dd45bb38b11d 731 Gene3D G3DSA:3.30.365.10 138 341 1.0E-59 T 23-10-2018 VMUT_1560 77b85573d9d073191a88dd45bb38b11d 731 Gene3D G3DSA:3.30.365.10 350 714 6.0E-108 T 23-10-2018 VMUT_1052 b93bf86051ef6e0bac2d7188c6a90f84 337 SUPERFAMILY SSF53448 1 297 2.03E-18 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1052 b93bf86051ef6e0bac2d7188c6a90f84 337 Gene3D G3DSA:3.90.550.10 1 247 2.0E-20 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1052 b93bf86051ef6e0bac2d7188c6a90f84 337 Pfam PF00535 Glycosyl transferase family 2 6 125 1.7E-10 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VMUT_0854 04afd0d12647f82900a83fe2dc6418e0 171 Gene3D G3DSA:3.30.300.310 101 169 1.9E-7 T 23-10-2018 VMUT_0854 04afd0d12647f82900a83fe2dc6418e0 171 SUPERFAMILY SSF56801 122 166 7.06E-8 T 23-10-2018 VMUT_0854 04afd0d12647f82900a83fe2dc6418e0 171 Pfam PF02596 Uncharacterised ArCR, COG2043 2 126 3.3E-19 T 23-10-2018 IPR003748 Protein of unknown function DUF169 VMUT_1243 3151e23a48700e24c6a9d660e429b59e 295 SUPERFAMILY SSF48179 170 290 2.49E-23 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VMUT_1243 3151e23a48700e24c6a9d660e429b59e 295 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 172 287 2.4E-18 T 23-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 VMUT_1243 3151e23a48700e24c6a9d660e429b59e 295 SUPERFAMILY SSF51735 1 145 3.64E-27 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1243 3151e23a48700e24c6a9d660e429b59e 295 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 158 1.4E-26 T 23-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 VMUT_1243 3151e23a48700e24c6a9d660e429b59e 295 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 23-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 VMUT_1243 3151e23a48700e24c6a9d660e429b59e 295 PIRSF PIRSF000103 1 295 2.1E-57 T 23-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 VMUT_1243 3151e23a48700e24c6a9d660e429b59e 295 Gene3D G3DSA:3.40.50.720 2 165 3.0E-36 T 23-10-2018 VMUT_1243 3151e23a48700e24c6a9d660e429b59e 295 Gene3D G3DSA:1.10.1040.10 166 293 1.3E-23 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VMUT_1730 1015df4fa848ce05f18c9bb7d6639cc8 231 Pfam PF01871 AMMECR1 39 181 8.9E-22 T 23-10-2018 IPR002733 AMMECR1 domain VMUT_1730 1015df4fa848ce05f18c9bb7d6639cc8 231 SUPERFAMILY SSF143447 5 219 7.06E-29 T 23-10-2018 IPR036071 AMMECR1 domain superfamily VMUT_1730 1015df4fa848ce05f18c9bb7d6639cc8 231 Gene3D G3DSA:3.30.1490.150 120 195 3.5E-24 T 23-10-2018 VMUT_1730 1015df4fa848ce05f18c9bb7d6639cc8 231 Gene3D G3DSA:3.30.700.20 14 199 3.5E-24 T 23-10-2018 IPR027485 AMMECR1, N-terminal VMUT_0445 a7616e76b09f1e4a6c4c7d160942b10e 393 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 9 135 5.3E-22 T 23-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 VMUT_0445 a7616e76b09f1e4a6c4c7d160942b10e 393 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 158 275 2.8E-16 T 23-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase VMUT_0445 a7616e76b09f1e4a6c4c7d160942b10e 393 SUPERFAMILY SSF69075 294 381 3.01E-15 T 23-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 VMUT_0445 a7616e76b09f1e4a6c4c7d160942b10e 393 Gene3D G3DSA:3.30.460.30 2 141 8.0E-23 T 23-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 VMUT_0445 a7616e76b09f1e4a6c4c7d160942b10e 393 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 294 377 1.5E-12 T 23-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 VMUT_0445 a7616e76b09f1e4a6c4c7d160942b10e 393 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 3 387 15.747 T 23-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 VMUT_0445 a7616e76b09f1e4a6c4c7d160942b10e 393 SUPERFAMILY SSF69742 4 138 6.15E-27 T 23-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 VMUT_0445 a7616e76b09f1e4a6c4c7d160942b10e 393 SUPERFAMILY SSF51735 158 255 2.17E-12 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0445 a7616e76b09f1e4a6c4c7d160942b10e 393 Gene3D G3DSA:3.40.50.720 143 275 7.4E-18 T 23-10-2018 VMUT_1263 5f2bf56523fcbc477122835ac9c9c497 265 SUPERFAMILY SSF51569 9 252 2.64E-79 T 23-10-2018 VMUT_1263 5f2bf56523fcbc477122835ac9c9c497 265 PIRSF PIRSF038992 2 265 6.3E-75 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 VMUT_1263 5f2bf56523fcbc477122835ac9c9c497 265 SMART SM01133 18 237 5.2E-44 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 VMUT_1263 5f2bf56523fcbc477122835ac9c9c497 265 Pfam PF01791 DeoC/LacD family aldolase 19 237 3.2E-40 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 VMUT_1263 5f2bf56523fcbc477122835ac9c9c497 265 Gene3D G3DSA:3.20.20.70 1 265 5.3E-93 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_1281 11e2681cd5b05a7137f36b90a9546102 630 ProSitePatterns PS00455 Putative AMP-binding domain signature. 244 255 - T 23-10-2018 IPR020845 AMP-binding, conserved site VMUT_1281 11e2681cd5b05a7137f36b90a9546102 630 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 19 66 2.8E-13 T 23-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 VMUT_1281 11e2681cd5b05a7137f36b90a9546102 630 Pfam PF00501 AMP-binding enzyme 72 503 2.2E-70 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VMUT_1281 11e2681cd5b05a7137f36b90a9546102 630 Pfam PF13193 AMP-binding enzyme C-terminal domain 514 588 4.3E-16 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VMUT_1281 11e2681cd5b05a7137f36b90a9546102 630 SUPERFAMILY SSF56801 7 618 1.02E-135 T 23-10-2018 VMUT_1281 11e2681cd5b05a7137f36b90a9546102 630 Gene3D G3DSA:3.40.50.12780 42 498 5.7E-90 T 23-10-2018 VMUT_1281 11e2681cd5b05a7137f36b90a9546102 630 Gene3D G3DSA:3.30.300.30 500 624 1.3E-22 T 23-10-2018 VMUT_0357 dabf113f69215cbe4708efc63a49bd06 318 SUPERFAMILY SSF52540 12 289 3.67E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0357 dabf113f69215cbe4708efc63a49bd06 318 Gene3D G3DSA:1.10.8.300 207 314 4.9E-26 T 23-10-2018 VMUT_0357 dabf113f69215cbe4708efc63a49bd06 318 Gene3D G3DSA:3.40.50.300 6 206 7.4E-49 T 23-10-2018 VMUT_0357 dabf113f69215cbe4708efc63a49bd06 318 PIRSF PIRSF002849 2 318 5.4E-120 T 23-10-2018 VMUT_0357 dabf113f69215cbe4708efc63a49bd06 318 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 44 174 1.8E-63 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 VMUT_0938 9a66bab08f3695cd2f0ebe28343ce2cd 737 Gene3D G3DSA:3.10.330.10 97 177 3.1E-10 T 23-10-2018 VMUT_0938 9a66bab08f3695cd2f0ebe28343ce2cd 737 SMART SM01072 112 176 8.9E-10 T 23-10-2018 IPR004201 CDC48, domain 2 VMUT_0938 9a66bab08f3695cd2f0ebe28343ce2cd 737 SUPERFAMILY SSF54585 97 187 2.62E-17 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily VMUT_0938 9a66bab08f3695cd2f0ebe28343ce2cd 737 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 113 175 6.0E-10 T 23-10-2018 IPR004201 CDC48, domain 2 VMUT_0938 9a66bab08f3695cd2f0ebe28343ce2cd 737 ProSitePatterns PS00674 AAA-protein family signature. 322 340 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 VMUT_0938 9a66bab08f3695cd2f0ebe28343ce2cd 737 Gene3D G3DSA:3.40.50.300 178 351 5.7E-71 T 23-10-2018 VMUT_0938 9a66bab08f3695cd2f0ebe28343ce2cd 737 Gene3D G3DSA:2.40.40.20 6 96 2.5E-27 T 23-10-2018 VMUT_0938 9a66bab08f3695cd2f0ebe28343ce2cd 737 Gene3D G3DSA:1.10.8.60 353 451 9.4E-29 T 23-10-2018 VMUT_0938 9a66bab08f3695cd2f0ebe28343ce2cd 737 SUPERFAMILY SSF52540 456 721 5.35E-80 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0938 9a66bab08f3695cd2f0ebe28343ce2cd 737 Gene3D G3DSA:3.40.50.300 456 717 2.3E-108 T 23-10-2018 VMUT_0938 9a66bab08f3695cd2f0ebe28343ce2cd 737 SMART SM00382 494 631 1.5E-23 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0938 9a66bab08f3695cd2f0ebe28343ce2cd 737 SMART SM00382 218 354 2.0E-23 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0938 9a66bab08f3695cd2f0ebe28343ce2cd 737 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 11 723 0.0 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 VMUT_0938 9a66bab08f3695cd2f0ebe28343ce2cd 737 SUPERFAMILY SSF52540 180 448 3.06E-73 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0938 9a66bab08f3695cd2f0ebe28343ce2cd 737 SUPERFAMILY SSF50692 8 94 7.46E-24 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily VMUT_0938 9a66bab08f3695cd2f0ebe28343ce2cd 737 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 13 95 6.9E-29 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain VMUT_0938 9a66bab08f3695cd2f0ebe28343ce2cd 737 ProSitePatterns PS00674 AAA-protein family signature. 599 617 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 VMUT_0938 9a66bab08f3695cd2f0ebe28343ce2cd 737 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 222 350 6.6E-49 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VMUT_0938 9a66bab08f3695cd2f0ebe28343ce2cd 737 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 498 628 2.7E-47 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VMUT_0938 9a66bab08f3695cd2f0ebe28343ce2cd 737 Gene3D G3DSA:1.10.8.60 630 702 2.3E-108 T 23-10-2018 VMUT_0938 9a66bab08f3695cd2f0ebe28343ce2cd 737 SMART SM01073 12 96 6.7E-31 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain VMUT_1934 dbd1f75168be03ad6d6e1f884962a58d 161 Pfam PF00731 AIR carboxylase 7 152 1.9E-66 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 VMUT_1934 dbd1f75168be03ad6d6e1f884962a58d 161 SUPERFAMILY SSF52255 5 156 1.44E-65 T 23-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 VMUT_1934 dbd1f75168be03ad6d6e1f884962a58d 161 SMART SM01001 5 154 6.9E-101 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 VMUT_1934 dbd1f75168be03ad6d6e1f884962a58d 161 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 7 156 7.8E-68 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 VMUT_1934 dbd1f75168be03ad6d6e1f884962a58d 161 Gene3D G3DSA:3.40.50.7700 1 160 1.8E-70 T 23-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 VMUT_1934 dbd1f75168be03ad6d6e1f884962a58d 161 PIRSF PIRSF001338 2 159 3.4E-68 T 23-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 VMUT_1934 dbd1f75168be03ad6d6e1f884962a58d 161 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 7 158 32.623 T 23-10-2018 IPR033747 Class I PurE VMUT_2066 fa13514ae75cc73a45353d703b11e3ca 359 Gene3D G3DSA:3.40.50.300 1 209 1.7E-47 T 23-10-2018 VMUT_2066 fa13514ae75cc73a45353d703b11e3ca 359 SUPERFAMILY SSF52540 2 284 2.7E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_2066 fa13514ae75cc73a45353d703b11e3ca 359 Gene3D G3DSA:1.10.10.10 288 359 6.4E-32 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_2066 fa13514ae75cc73a45353d703b11e3ca 359 Gene3D G3DSA:1.10.8.60 210 287 2.5E-29 T 23-10-2018 VMUT_2066 fa13514ae75cc73a45353d703b11e3ca 359 Pfam PF01637 ATPase domain predominantly from Archaea 14 250 1.9E-20 T 23-10-2018 IPR011579 ATPase domain GO:0005524 VMUT_2066 fa13514ae75cc73a45353d703b11e3ca 359 SUPERFAMILY SSF46785 291 358 1.2E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_2300 8e88d117e61abde9c2625c5693a86d86 470 Gene3D G3DSA:3.40.120.10 176 362 1.6E-54 T 23-10-2018 VMUT_2300 8e88d117e61abde9c2625c5693a86d86 470 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 411 463 3.8E-12 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VMUT_2300 8e88d117e61abde9c2625c5693a86d86 470 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 4 134 1.4E-33 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VMUT_2300 8e88d117e61abde9c2625c5693a86d86 470 SUPERFAMILY SSF53738 248 381 1.29E-22 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VMUT_2300 8e88d117e61abde9c2625c5693a86d86 470 SUPERFAMILY SSF53738 4 184 1.88E-36 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VMUT_2300 8e88d117e61abde9c2625c5693a86d86 470 Gene3D G3DSA:3.40.120.10 260 344 1.6E-54 T 23-10-2018 VMUT_2300 8e88d117e61abde9c2625c5693a86d86 470 SUPERFAMILY SSF55957 368 465 7.85E-22 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VMUT_2300 8e88d117e61abde9c2625c5693a86d86 470 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 3.9E-10 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VMUT_2300 8e88d117e61abde9c2625c5693a86d86 470 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 211 224 3.9E-10 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VMUT_2300 8e88d117e61abde9c2625c5693a86d86 470 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 239 254 3.9E-10 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VMUT_2300 8e88d117e61abde9c2625c5693a86d86 470 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 177 196 3.9E-10 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VMUT_2300 8e88d117e61abde9c2625c5693a86d86 470 SUPERFAMILY SSF53738 163 260 6.28E-24 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VMUT_2300 8e88d117e61abde9c2625c5693a86d86 470 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 264 374 9.3E-19 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VMUT_2300 8e88d117e61abde9c2625c5693a86d86 470 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 159 257 7.0E-25 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VMUT_2300 8e88d117e61abde9c2625c5693a86d86 470 Gene3D G3DSA:3.30.310.50 377 464 3.0E-20 T 23-10-2018 VMUT_2300 8e88d117e61abde9c2625c5693a86d86 470 Gene3D G3DSA:3.40.120.10 1 146 8.0E-36 T 23-10-2018 VMUT_2032 14838e9ffd6e1ae1a4ffecc2de1a36a4 199 Gene3D G3DSA:3.30.2170.10 11 198 1.8E-53 T 23-10-2018 VMUT_2032 14838e9ffd6e1ae1a4ffecc2de1a36a4 199 PIRSF PIRSF006380 6 198 1.5E-47 T 23-10-2018 IPR002802 Protein of unknown function DUF99 VMUT_2032 14838e9ffd6e1ae1a4ffecc2de1a36a4 199 Hamap MF_00582 UPF0215 protein . 16 194 25.074 T 23-10-2018 IPR002802 Protein of unknown function DUF99 VMUT_2032 14838e9ffd6e1ae1a4ffecc2de1a36a4 199 ProDom PD016744 UPF0215 ST0304 TK2033 MA4269 PAE0952 SSO0256 NEQ431 MK0057 PTO0905 TV0037 73 191 9.0E-22 T 23-10-2018 IPR002802 Protein of unknown function DUF99 VMUT_2032 14838e9ffd6e1ae1a4ffecc2de1a36a4 199 Pfam PF01949 Protein of unknown function DUF99 15 192 1.1E-61 T 23-10-2018 IPR002802 Protein of unknown function DUF99 VMUT_1530 596f84dedee6ea38f65e9df6b3e21ed7 326 Pfam PF00742 Homoserine dehydrogenase 156 317 3.7E-44 T 23-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 VMUT_1530 596f84dedee6ea38f65e9df6b3e21ed7 326 SUPERFAMILY SSF55347 158 304 6.54E-41 T 23-10-2018 VMUT_1530 596f84dedee6ea38f65e9df6b3e21ed7 326 Gene3D G3DSA:3.40.50.720 6 317 2.1E-91 T 23-10-2018 VMUT_1530 596f84dedee6ea38f65e9df6b3e21ed7 326 PIRSF PIRSF036497 1 324 7.7E-84 T 23-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 VMUT_1530 596f84dedee6ea38f65e9df6b3e21ed7 326 Gene3D G3DSA:3.30.360.10 160 300 2.1E-91 T 23-10-2018 VMUT_1530 596f84dedee6ea38f65e9df6b3e21ed7 326 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 140 3.2E-7 T 23-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 VMUT_1530 596f84dedee6ea38f65e9df6b3e21ed7 326 SUPERFAMILY SSF51735 1 170 1.35E-21 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1666 33f3536dcb336f28c2740da1315261ce 200 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 113 119 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 VMUT_1666 33f3536dcb336f28c2740da1315261ce 200 Pfam PF05175 Methyltransferase small domain 28 122 1.6E-8 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 VMUT_1666 33f3536dcb336f28c2740da1315261ce 200 SUPERFAMILY SSF53335 9 189 2.99E-19 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_1666 33f3536dcb336f28c2740da1315261ce 200 Gene3D G3DSA:3.40.50.150 9 200 6.4E-23 T 23-10-2018 VMUT_0266 5fcbc23c07972ab7b6d08e29b5fc2dad 611 SUPERFAMILY SSF56235 2 228 3.43E-70 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VMUT_0266 5fcbc23c07972ab7b6d08e29b5fc2dad 611 Gene3D G3DSA:3.40.50.10490 255 610 2.6E-122 T 23-10-2018 VMUT_0266 5fcbc23c07972ab7b6d08e29b5fc2dad 611 Pfam PF13522 Glutamine amidotransferase domain 68 198 3.4E-24 T 23-10-2018 VMUT_0266 5fcbc23c07972ab7b6d08e29b5fc2dad 611 Gene3D G3DSA:3.40.50.10490 447 596 2.6E-122 T 23-10-2018 VMUT_0266 5fcbc23c07972ab7b6d08e29b5fc2dad 611 Pfam PF01380 SIS domain 290 416 9.5E-29 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 VMUT_0266 5fcbc23c07972ab7b6d08e29b5fc2dad 611 Pfam PF01380 SIS domain 464 593 7.4E-13 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 VMUT_0266 5fcbc23c07972ab7b6d08e29b5fc2dad 611 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 611 1.2E-221 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 VMUT_0266 5fcbc23c07972ab7b6d08e29b5fc2dad 611 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 611 37.847 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 VMUT_0266 5fcbc23c07972ab7b6d08e29b5fc2dad 611 Gene3D G3DSA:3.60.20.10 2 239 7.7E-74 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VMUT_0266 5fcbc23c07972ab7b6d08e29b5fc2dad 611 SUPERFAMILY SSF53697 253 611 3.8E-102 T 23-10-2018 VMUT_1938 bc57cf31e818bf58c96f73abd02f2d33 333 SUPERFAMILY SSF55326 3 154 2.44E-26 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily VMUT_1938 bc57cf31e818bf58c96f73abd02f2d33 333 Gene3D G3DSA:3.30.1330.10 2 159 5.0E-33 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily VMUT_1938 bc57cf31e818bf58c96f73abd02f2d33 333 Gene3D G3DSA:3.90.650.10 160 328 2.8E-43 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily VMUT_1938 bc57cf31e818bf58c96f73abd02f2d33 333 Pfam PF02769 AIR synthase related protein, C-terminal domain 164 323 3.5E-20 T 23-10-2018 IPR010918 PurM-like, C-terminal domain VMUT_1938 bc57cf31e818bf58c96f73abd02f2d33 333 SUPERFAMILY SSF56042 161 321 1.94E-36 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily VMUT_1938 bc57cf31e818bf58c96f73abd02f2d33 333 Pfam PF00586 AIR synthase related protein, N-terminal domain 54 154 5.2E-12 T 23-10-2018 IPR016188 PurM-like, N-terminal domain VMUT_1938 bc57cf31e818bf58c96f73abd02f2d33 333 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 4 317 5.4E-73 T 23-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 VMUT_0175 96bdf24bda79a644af20fc02e7234380 291 SUPERFAMILY SSF100950 10 268 1.26E-35 T 23-10-2018 IPR037171 NagB/RpiA transferase-like VMUT_0175 96bdf24bda79a644af20fc02e7234380 291 Pfam PF01008 Initiation factor 2 subunit family 30 268 9.7E-21 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 VMUT_0175 96bdf24bda79a644af20fc02e7234380 291 Gene3D G3DSA:1.20.120.420 7 83 6.8E-6 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 VMUT_0175 96bdf24bda79a644af20fc02e7234380 291 Gene3D G3DSA:3.40.50.10470 106 272 6.7E-28 T 23-10-2018 VMUT_0405 f4c23804a3bddf1250f74dd276be1131 57 Gene3D G3DSA:1.10.620.20 2 51 2.3E-10 T 23-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 VMUT_0405 f4c23804a3bddf1250f74dd276be1131 57 SMART SM00746 6 43 4.6E-11 T 23-10-2018 IPR011017 TRASH domain VMUT_0405 f4c23804a3bddf1250f74dd276be1131 57 SUPERFAMILY SSF47240 3 46 5.68E-10 T 23-10-2018 IPR009078 Ferritin-like superfamily VMUT_0405 f4c23804a3bddf1250f74dd276be1131 57 Pfam PF04945 YHS domain 4 48 1.1E-18 T 23-10-2018 IPR007029 YHS domain VMUT_1328 da7bd92da144e543163ab20800eab827 255 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 165 176 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_1328 da7bd92da144e543163ab20800eab827 255 Gene3D G3DSA:3.10.20.30 12 118 6.8E-36 T 23-10-2018 IPR012675 Beta-grasp domain superfamily VMUT_1328 da7bd92da144e543163ab20800eab827 255 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 20 124 1.3E-34 T 23-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 VMUT_1328 da7bd92da144e543163ab20800eab827 255 SUPERFAMILY SSF54292 17 118 8.13E-30 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VMUT_1328 da7bd92da144e543163ab20800eab827 255 SUPERFAMILY SSF46548 120 248 4.71E-30 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VMUT_1328 da7bd92da144e543163ab20800eab827 255 Gene3D G3DSA:1.10.1060.10 119 252 6.3E-42 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VMUT_1328 da7bd92da144e543163ab20800eab827 255 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 23 245 2.7E-75 T 23-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 VMUT_1328 da7bd92da144e543163ab20800eab827 255 Pfam PF13183 4Fe-4S dicluster domain 162 235 1.6E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_1328 da7bd92da144e543163ab20800eab827 255 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 69 77 - T 23-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VMUT_2259 0915ca44227697929c91f9ac407d4d81 114 Gene3D G3DSA:3.40.50.720 1 108 1.3E-32 T 23-10-2018 VMUT_2259 0915ca44227697929c91f9ac407d4d81 114 SUPERFAMILY SSF51735 1 95 8.95E-31 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_2259 0915ca44227697929c91f9ac407d4d81 114 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 7.8E-12 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_2259 0915ca44227697929c91f9ac407d4d81 114 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 7.8E-12 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_2259 0915ca44227697929c91f9ac407d4d81 114 Pfam PF00106 short chain dehydrogenase 9 94 9.8E-25 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0189 253e491840ff6464b96324b90a129431 369 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 301 313 - T 23-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site VMUT_0189 253e491840ff6464b96324b90a129431 369 Gene3D G3DSA:3.90.230.10 145 369 8.6E-76 T 23-10-2018 VMUT_0189 253e491840ff6464b96324b90a129431 369 Pfam PF01321 Creatinase/Prolidase N-terminal domain 7 143 4.2E-6 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 VMUT_0189 253e491840ff6464b96324b90a129431 369 Gene3D G3DSA:3.40.350.10 3 144 4.8E-10 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal VMUT_0189 253e491840ff6464b96324b90a129431 369 SUPERFAMILY SSF55920 145 368 6.41E-71 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like VMUT_0189 253e491840ff6464b96324b90a129431 369 Pfam PF00557 Metallopeptidase family M24 153 355 2.8E-60 T 23-10-2018 IPR000994 Peptidase M24 VMUT_0189 253e491840ff6464b96324b90a129431 369 SUPERFAMILY SSF53092 5 78 1.55E-8 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal VMUT_1403 ab455f865de8b407181453892d611a3b 130 Pfam PF01850 PIN domain 3 121 1.4E-13 T 23-10-2018 IPR002716 PIN domain VMUT_1403 ab455f865de8b407181453892d611a3b 130 SUPERFAMILY SSF88723 3 128 4.21E-21 T 23-10-2018 IPR029060 PIN-like domain superfamily VMUT_1403 ab455f865de8b407181453892d611a3b 130 Gene3D G3DSA:3.40.50.1010 2 124 2.1E-30 T 23-10-2018 VMUT_1127 88f1fb5cdc225f751e78d5299745ebae 230 SUPERFAMILY SSF48150 27 226 5.18E-43 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 VMUT_1127 88f1fb5cdc225f751e78d5299745ebae 230 Gene3D G3DSA:1.10.340.30 35 149 4.8E-38 T 23-10-2018 VMUT_1127 88f1fb5cdc225f751e78d5299745ebae 230 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 47 182 1.3E-8 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 VMUT_1127 88f1fb5cdc225f751e78d5299745ebae 230 Gene3D G3DSA:1.10.1670.10 33 223 4.8E-38 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 VMUT_1127 88f1fb5cdc225f751e78d5299745ebae 230 SMART SM00525 206 226 7.1E-4 T 23-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 VMUT_1127 88f1fb5cdc225f751e78d5299745ebae 230 SMART SM00478 50 205 6.5E-18 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 VMUT_1127 88f1fb5cdc225f751e78d5299745ebae 230 PIRSF PIRSF001435 11 229 1.1E-55 T 23-10-2018 VMUT_0700 81f4fe5f752c04ae9f8d400bac028efe 252 SUPERFAMILY SSF46785 192 249 4.19E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0700 81f4fe5f752c04ae9f8d400bac028efe 252 Gene3D G3DSA:3.40.50.150 27 182 1.0E-46 T 23-10-2018 VMUT_0700 81f4fe5f752c04ae9f8d400bac028efe 252 SUPERFAMILY SSF53335 34 184 6.5E-31 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_0700 81f4fe5f752c04ae9f8d400bac028efe 252 Pfam PF02353 Mycolic acid cyclopropane synthetase 41 116 5.1E-7 T 23-10-2018 VMUT_1511 c6f4b8133e57882ef896c6a9e04c15b0 326 Pfam PF01878 EVE domain 17 152 4.2E-6 T 23-10-2018 IPR002740 EVE domain VMUT_1511 c6f4b8133e57882ef896c6a9e04c15b0 326 Gene3D G3DSA:3.10.590.10 15 152 1.3E-10 T 23-10-2018 VMUT_1511 c6f4b8133e57882ef896c6a9e04c15b0 326 SUPERFAMILY SSF88697 17 153 8.2E-15 T 23-10-2018 IPR015947 PUA-like superfamily VMUT_2025 b90852faebf577f68b54af64a4322af0 519 Pfam PF02538 Hydantoinase B/oxoprolinase 3 517 5.5E-191 T 23-10-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 VMUT_2137 8608a0f38145f703270d9f170fd6f0eb 108 SUPERFAMILY SSF54862 8 82 1.35E-19 T 23-10-2018 VMUT_2137 8608a0f38145f703270d9f170fd6f0eb 108 Pfam PF12837 4Fe-4S binding domain 10 33 4.4E-10 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_2137 8608a0f38145f703270d9f170fd6f0eb 108 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 18 29 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_2137 8608a0f38145f703270d9f170fd6f0eb 108 Gene3D G3DSA:3.30.70.20 5 71 1.3E-14 T 23-10-2018 VMUT_1654 83d07df49ff485b2b4f5579396418c7d 434 SUPERFAMILY SSF52096 5 191 1.09E-24 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VMUT_1654 83d07df49ff485b2b4f5579396418c7d 434 Pfam PF00574 Clp protease 31 147 3.5E-4 T 23-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA VMUT_1654 83d07df49ff485b2b4f5579396418c7d 434 SUPERFAMILY SSF141322 380 433 7.06E-10 T 23-10-2018 VMUT_1654 83d07df49ff485b2b4f5579396418c7d 434 Gene3D G3DSA:2.40.50.140 378 434 1.2E-11 T 23-10-2018 VMUT_1654 83d07df49ff485b2b4f5579396418c7d 434 Pfam PF01957 NfeD-like C-terminal, partner-binding 284 433 9.1E-18 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain VMUT_1654 83d07df49ff485b2b4f5579396418c7d 434 Gene3D G3DSA:3.90.226.10 23 238 4.8E-41 T 23-10-2018 VMUT_2065 a68333153988428e953e539dc3d1cbff 185 Pfam PF01661 Macro domain 28 141 1.8E-37 T 23-10-2018 IPR002589 Macro domain VMUT_2065 a68333153988428e953e539dc3d1cbff 185 SMART SM00506 11 141 5.6E-48 T 23-10-2018 IPR002589 Macro domain VMUT_2065 a68333153988428e953e539dc3d1cbff 185 Gene3D G3DSA:3.40.220.10 3 177 1.1E-61 T 23-10-2018 VMUT_2065 a68333153988428e953e539dc3d1cbff 185 SUPERFAMILY SSF52949 7 178 1.24E-59 T 23-10-2018 VMUT_0053 c7c96f036efe4923623ec4daa4560427 304 SUPERFAMILY SSF117892 108 214 5.75E-10 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily VMUT_0053 c7c96f036efe4923623ec4daa4560427 304 Pfam PF01145 SPFH domain / Band 7 family 40 222 8.7E-18 T 23-10-2018 IPR001107 Band 7 domain VMUT_0163 dc5b039971f82dbb414bd4e20dd8aa1c 384 SUPERFAMILY SSF102114 19 235 5.89E-14 T 23-10-2018 VMUT_0163 dc5b039971f82dbb414bd4e20dd8aa1c 384 Gene3D G3DSA:3.20.20.70 37 244 1.4E-5 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_1433 a3071869d195d5dce4b70c4d3db84573 68 SUPERFAMILY SSF46785 9 67 6.26E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_1433 a3071869d195d5dce4b70c4d3db84573 68 Gene3D G3DSA:1.10.10.10 7 68 3.3E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_0612 9382c14d9357e6c6b5ba5cd9eff9cb00 213 Gene3D G3DSA:3.30.420.100 1 197 7.7E-73 T 23-10-2018 VMUT_0612 9382c14d9357e6c6b5ba5cd9eff9cb00 213 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 100 132 3.9E-10 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0612 9382c14d9357e6c6b5ba5cd9eff9cb00 213 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 6 96 1.5E-23 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0612 9382c14d9357e6c6b5ba5cd9eff9cb00 213 SUPERFAMILY SSF53137 3 194 1.42E-63 T 23-10-2018 VMUT_0612 9382c14d9357e6c6b5ba5cd9eff9cb00 213 Pfam PF14204 Ribosomal L18 C-terminal region 141 193 6.6E-11 T 23-10-2018 IPR025607 Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0612 9382c14d9357e6c6b5ba5cd9eff9cb00 213 Hamap MF_01337_A 50S ribosomal protein L18 [rplR]. 5 191 40.811 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0332 a0ee1796f69243d49720dc07b3e55ad3 395 Pfam PF07690 Major Facilitator Superfamily 12 350 2.1E-21 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_0332 a0ee1796f69243d49720dc07b3e55ad3 395 SUPERFAMILY SSF103473 2 391 2.88E-43 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_0332 a0ee1796f69243d49720dc07b3e55ad3 395 Gene3D G3DSA:1.20.1250.20 1 196 1.3E-18 T 23-10-2018 VMUT_0332 a0ee1796f69243d49720dc07b3e55ad3 395 Gene3D G3DSA:1.20.1250.20 207 393 1.9E-12 T 23-10-2018 VMUT_1046 1b686fea37f5208a36e06f58e90612b9 389 Pfam PF13439 Glycosyltransferase Family 4 11 189 1.8E-26 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 VMUT_1046 1b686fea37f5208a36e06f58e90612b9 389 Gene3D G3DSA:3.40.50.2000 1 383 2.0E-73 T 23-10-2018 VMUT_1046 1b686fea37f5208a36e06f58e90612b9 389 Pfam PF00534 Glycosyl transferases group 1 201 365 2.6E-32 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 VMUT_1046 1b686fea37f5208a36e06f58e90612b9 389 SUPERFAMILY SSF53756 5 388 3.27E-82 T 23-10-2018 VMUT_1046 1b686fea37f5208a36e06f58e90612b9 389 Gene3D G3DSA:3.40.50.2000 186 367 2.0E-73 T 23-10-2018 VMUT_0937 7347f029517a508cd384b6f66c56f6e8 92 SMART SM00888 3 90 1.9E-23 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 VMUT_0937 7347f029517a508cd384b6f66c56f6e8 92 Hamap MF_00043 Elongation factor 1-beta [ef1b]. 1 92 36.721 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 VMUT_0937 7347f029517a508cd384b6f66c56f6e8 92 SUPERFAMILY SSF54984 1 90 4.19E-20 T 23-10-2018 IPR036219 Translation elongation factor eEF-1beta-like superfamily Reactome: R-HSA-156842 VMUT_0937 7347f029517a508cd384b6f66c56f6e8 92 PIRSF PIRSF006521 1 90 7.5E-29 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 VMUT_0937 7347f029517a508cd384b6f66c56f6e8 92 Gene3D G3DSA:3.30.70.60 1 90 2.1E-24 T 23-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 VMUT_0937 7347f029517a508cd384b6f66c56f6e8 92 TIGRFAM TIGR00489 aEF-1_beta: translation elongation factor aEF-1 beta 1 87 3.9E-18 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 VMUT_0937 7347f029517a508cd384b6f66c56f6e8 92 Pfam PF00736 EF-1 guanine nucleotide exchange domain 6 90 1.6E-14 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 VMUT_2159 abc50a6feec0a4c591a03fedfcb26643 307 SUPERFAMILY SSF52283 1 134 8.69E-34 T 23-10-2018 VMUT_2159 abc50a6feec0a4c591a03fedfcb26643 307 SUPERFAMILY SSF51735 98 283 2.08E-55 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_2159 abc50a6feec0a4c591a03fedfcb26643 307 Gene3D G3DSA:3.40.50.720 5 299 8.6E-118 T 23-10-2018 VMUT_2159 abc50a6feec0a4c591a03fedfcb26643 307 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 283 2.0E-58 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 VMUT_2159 abc50a6feec0a4c591a03fedfcb26643 307 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 143 170 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 VMUT_2159 abc50a6feec0a4c591a03fedfcb26643 307 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 306 4.3E-35 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 VMUT_2159 abc50a6feec0a4c591a03fedfcb26643 307 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 220 236 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site VMUT_2159 abc50a6feec0a4c591a03fedfcb26643 307 Gene3D G3DSA:3.40.50.720 93 285 8.6E-118 T 23-10-2018 VMUT_0152 0785c1d8f43fd7f56c4c8a44603c2e96 629 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 514 584 2.2E-8 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II VMUT_0152 0785c1d8f43fd7f56c4c8a44603c2e96 629 SUPERFAMILY SSF52922 504 621 1.57E-18 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VMUT_0152 0785c1d8f43fd7f56c4c8a44603c2e96 629 SUPERFAMILY SSF53323 6 259 1.31E-11 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 VMUT_0152 0785c1d8f43fd7f56c4c8a44603c2e96 629 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 251 483 7.9E-61 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 VMUT_0152 0785c1d8f43fd7f56c4c8a44603c2e96 629 Gene3D G3DSA:3.40.50.970 228 430 1.0E-70 T 23-10-2018 VMUT_0152 0785c1d8f43fd7f56c4c8a44603c2e96 629 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 13 214 3.1E-35 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 VMUT_0152 0785c1d8f43fd7f56c4c8a44603c2e96 629 Gene3D G3DSA:3.40.50.920 500 619 9.0E-28 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VMUT_0152 0785c1d8f43fd7f56c4c8a44603c2e96 629 SUPERFAMILY SSF52518 240 493 3.49E-59 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold VMUT_0152 0785c1d8f43fd7f56c4c8a44603c2e96 629 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 5 612 3.6E-165 T 23-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 VMUT_0650 195ca7f3c36145fdd7acddbc612e8049 625 Pfam PF02934 GatB/GatE catalytic domain 14 449 7.4E-66 T 23-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 VMUT_0650 195ca7f3c36145fdd7acddbc612e8049 625 SUPERFAMILY SSF89095 498 623 1.05E-11 T 23-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 VMUT_0650 195ca7f3c36145fdd7acddbc612e8049 625 SUPERFAMILY SSF55931 7 456 5.1E-98 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 VMUT_0650 195ca7f3c36145fdd7acddbc612e8049 625 Gene3D G3DSA:3.30.1360.30 277 407 9.4E-40 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 VMUT_0650 195ca7f3c36145fdd7acddbc612e8049 625 SUPERFAMILY SSF55261 281 407 2.4E-37 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 VMUT_0650 195ca7f3c36145fdd7acddbc612e8049 625 Pfam PF02938 GAD domain 302 375 3.1E-9 T 23-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 VMUT_0650 195ca7f3c36145fdd7acddbc612e8049 625 ProDom PD609240 SUBUNIT E AMIDOTRANSFERASE 6.3.5.- LIGASE GLUTAMYL-TRNAGLN GLU-ADT BIOSYNTHESIS TRANSFERASE B 288 409 3.0E-39 T 23-10-2018 VMUT_0650 195ca7f3c36145fdd7acddbc612e8049 625 Pfam PF02637 GatB domain 500 623 4.1E-10 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 VMUT_0650 195ca7f3c36145fdd7acddbc612e8049 625 SMART SM00845 486 623 1.1E-8 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 VMUT_0650 195ca7f3c36145fdd7acddbc612e8049 625 Hamap MF_00588 Glutamyl-tRNA(Gln) amidotransferase subunit E [gatE]. 1 625 284.064 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 VMUT_0650 195ca7f3c36145fdd7acddbc612e8049 625 Gene3D G3DSA:1.10.150.380 456 552 2.0E-17 T 23-10-2018 VMUT_0650 195ca7f3c36145fdd7acddbc612e8049 625 TIGRFAM TIGR00134 gatE_arch: glutamyl-tRNA(Gln) amidotransferase, subunit E 6 617 6.9E-202 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 VMUT_0606 318fa6b116205a0237903a7ca5fcab43 255 Gene3D G3DSA:3.10.580.10 65 188 8.5E-27 T 23-10-2018 VMUT_0606 318fa6b116205a0237903a7ca5fcab43 255 SUPERFAMILY SSF54631 125 253 2.74E-30 T 23-10-2018 VMUT_0606 318fa6b116205a0237903a7ca5fcab43 255 SUPERFAMILY SSF54631 1 120 4.55E-20 T 23-10-2018 VMUT_0606 318fa6b116205a0237903a7ca5fcab43 255 Pfam PF00571 CBS domain 131 184 9.3E-12 T 23-10-2018 IPR000644 CBS domain VMUT_0606 318fa6b116205a0237903a7ca5fcab43 255 Pfam PF00571 CBS domain 74 122 7.0E-7 T 23-10-2018 IPR000644 CBS domain VMUT_0606 318fa6b116205a0237903a7ca5fcab43 255 Pfam PF00571 CBS domain 201 252 3.3E-13 T 23-10-2018 IPR000644 CBS domain VMUT_0606 318fa6b116205a0237903a7ca5fcab43 255 Pfam PF00571 CBS domain 3 48 4.8E-4 T 23-10-2018 IPR000644 CBS domain VMUT_0606 318fa6b116205a0237903a7ca5fcab43 255 Gene3D G3DSA:3.10.580.10 189 254 4.7E-16 T 23-10-2018 VMUT_0606 318fa6b116205a0237903a7ca5fcab43 255 SMART SM00116 138 185 1.3E-9 T 23-10-2018 IPR000644 CBS domain VMUT_0606 318fa6b116205a0237903a7ca5fcab43 255 SMART SM00116 10 57 0.026 T 23-10-2018 IPR000644 CBS domain VMUT_0606 318fa6b116205a0237903a7ca5fcab43 255 SMART SM00116 207 254 4.8E-11 T 23-10-2018 IPR000644 CBS domain VMUT_0606 318fa6b116205a0237903a7ca5fcab43 255 SMART SM00116 75 122 0.025 T 23-10-2018 IPR000644 CBS domain VMUT_0606 318fa6b116205a0237903a7ca5fcab43 255 Gene3D G3DSA:3.10.580.10 1 64 5.4E-8 T 23-10-2018 VMUT_1670 25c5019642dec56e036c9bed7135244f 193 Hamap MF_00408 TATA-box-binding protein [tbp]. 2 181 38.245 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 VMUT_1670 25c5019642dec56e036c9bed7135244f 193 PRINTS PR00686 Transcription initiation factor TFIID signature 8 23 1.2E-47 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 VMUT_1670 25c5019642dec56e036c9bed7135244f 193 PRINTS PR00686 Transcription initiation factor TFIID signature 32 51 1.2E-47 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 VMUT_1670 25c5019642dec56e036c9bed7135244f 193 PRINTS PR00686 Transcription initiation factor TFIID signature 141 157 1.2E-47 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 VMUT_1670 25c5019642dec56e036c9bed7135244f 193 PRINTS PR00686 Transcription initiation factor TFIID signature 122 137 1.2E-47 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 VMUT_1670 25c5019642dec56e036c9bed7135244f 193 PRINTS PR00686 Transcription initiation factor TFIID signature 99 115 1.2E-47 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 VMUT_1670 25c5019642dec56e036c9bed7135244f 193 PRINTS PR00686 Transcription initiation factor TFIID signature 51 69 1.2E-47 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 VMUT_1670 25c5019642dec56e036c9bed7135244f 193 Gene3D G3DSA:3.30.310.10 91 182 2.3E-34 T 23-10-2018 IPR012295 TBP domain superfamily VMUT_1670 25c5019642dec56e036c9bed7135244f 193 Gene3D G3DSA:3.30.310.10 2 89 5.1E-32 T 23-10-2018 IPR012295 TBP domain superfamily VMUT_1670 25c5019642dec56e036c9bed7135244f 193 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 6 86 4.4E-31 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 VMUT_1670 25c5019642dec56e036c9bed7135244f 193 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 97 177 2.7E-29 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 VMUT_1670 25c5019642dec56e036c9bed7135244f 193 SUPERFAMILY SSF55945 4 93 2.83E-31 T 23-10-2018 VMUT_1670 25c5019642dec56e036c9bed7135244f 193 SUPERFAMILY SSF55945 95 179 1.33E-30 T 23-10-2018 VMUT_1670 25c5019642dec56e036c9bed7135244f 193 ProSitePatterns PS00351 Transcription factor TFIID repeat signature. 126 175 - T 23-10-2018 IPR030491 TATA-box binding protein, conserved site VMUT_0611 ea7d42b2df4e2f355061bee2623c5859 148 Pfam PF01280 Ribosomal protein L19e 4 141 7.0E-47 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0611 ea7d42b2df4e2f355061bee2623c5859 148 SMART SM01416 1 143 2.0E-64 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0611 ea7d42b2df4e2f355061bee2623c5859 148 Hamap MF_01475 50S ribosomal protein L19e [rpl19e]. 3 146 23.407 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0611 ea7d42b2df4e2f355061bee2623c5859 148 SUPERFAMILY SSF48140 4 139 2.48E-44 T 23-10-2018 IPR035970 Ribosomal protein L19/L19e superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0611 ea7d42b2df4e2f355061bee2623c5859 148 Gene3D G3DSA:1.10.1200.240 55 148 1.0E-23 T 23-10-2018 VMUT_0611 ea7d42b2df4e2f355061bee2623c5859 148 Gene3D G3DSA:1.10.1650.10 2 51 1.8E-14 T 23-10-2018 IPR015972 Ribosomal protein L19/L19e, domain 1 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1363 a6009d5efaaacc253523ec6be75c56c9 463 SUPERFAMILY SSF51905 3 355 3.56E-39 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_1363 a6009d5efaaacc253523ec6be75c56c9 463 Pfam PF04324 BFD-like [2Fe-2S] binding domain 391 441 1.1E-12 T 23-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain VMUT_1363 a6009d5efaaacc253523ec6be75c56c9 463 Gene3D G3DSA:1.10.10.1100 382 451 1.1E-16 T 23-10-2018 VMUT_1363 a6009d5efaaacc253523ec6be75c56c9 463 Gene3D G3DSA:3.30.9.10 86 312 5.6E-79 T 23-10-2018 VMUT_1363 a6009d5efaaacc253523ec6be75c56c9 463 Gene3D G3DSA:3.50.50.60 4 346 5.6E-79 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_1363 a6009d5efaaacc253523ec6be75c56c9 463 Pfam PF01266 FAD dependent oxidoreductase 4 351 7.5E-51 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VMUT_1044 d01a9acb57e9c6b691f08f674bfa6a9b 332 SUPERFAMILY SSF51735 4 191 1.38E-28 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1044 d01a9acb57e9c6b691f08f674bfa6a9b 332 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 148 199 1.2E-4 T 23-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 VMUT_1044 d01a9acb57e9c6b691f08f674bfa6a9b 332 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 121 8.4E-14 T 23-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 VMUT_1044 d01a9acb57e9c6b691f08f674bfa6a9b 332 SUPERFAMILY SSF55347 128 289 4.58E-7 T 23-10-2018 VMUT_1044 d01a9acb57e9c6b691f08f674bfa6a9b 332 Gene3D G3DSA:3.30.360.10 123 279 1.8E-37 T 23-10-2018 VMUT_1044 d01a9acb57e9c6b691f08f674bfa6a9b 332 Gene3D G3DSA:3.40.50.720 4 303 1.8E-37 T 23-10-2018 VMUT_0088 a4e4f03e038b2cc286311c7d15c778c7 79 Pfam PF01206 Sulfurtransferase TusA 7 75 2.6E-7 T 23-10-2018 IPR001455 TusA-like domain VMUT_0088 a4e4f03e038b2cc286311c7d15c778c7 79 Gene3D G3DSA:3.30.110.40 4 75 2.5E-6 T 23-10-2018 IPR036868 TusA-like domain superfamily VMUT_0088 a4e4f03e038b2cc286311c7d15c778c7 79 SUPERFAMILY SSF64307 6 75 5.23E-11 T 23-10-2018 IPR036868 TusA-like domain superfamily VMUT_0825 5ea6d961d2b60bf8b2f9188624d52ea8 581 Pfam PF02080 TrkA-C domain 319 387 3.1E-8 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 VMUT_0825 5ea6d961d2b60bf8b2f9188624d52ea8 581 Gene3D G3DSA:3.30.70.1450 316 389 2.0E-13 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 VMUT_0825 5ea6d961d2b60bf8b2f9188624d52ea8 581 SUPERFAMILY SSF116726 318 394 1.96E-15 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 VMUT_0825 5ea6d961d2b60bf8b2f9188624d52ea8 581 Pfam PF03600 Citrate transporter 38 533 1.3E-44 T 23-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 VMUT_1941 feb473c52eb689c21e9dc914db5f9afc 398 SUPERFAMILY SSF56059 119 391 1.91E-53 T 23-10-2018 VMUT_1941 feb473c52eb689c21e9dc914db5f9afc 398 Gene3D G3DSA:3.30.470.20 196 398 4.4E-55 T 23-10-2018 VMUT_1941 feb473c52eb689c21e9dc914db5f9afc 398 SUPERFAMILY SSF52440 3 111 1.58E-32 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily VMUT_1941 feb473c52eb689c21e9dc914db5f9afc 398 Gene3D G3DSA:3.40.50.20 1 123 6.2E-48 T 23-10-2018 VMUT_1941 feb473c52eb689c21e9dc914db5f9afc 398 Gene3D G3DSA:3.30.1490.20 124 195 1.6E-23 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VMUT_1941 feb473c52eb689c21e9dc914db5f9afc 398 Pfam PF02222 ATP-grasp domain 122 300 5.4E-42 T 23-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type VMUT_1941 feb473c52eb689c21e9dc914db5f9afc 398 Hamap MF_01643 Formate-dependent phosphoribosylglycinamide formyltransferase [purT]. 7 398 46.688 T 23-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 VMUT_0492 df65d3b8cec2f420a9fed0d91a78a15a 458 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 10 423 1.6E-123 T 23-10-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 VMUT_0492 df65d3b8cec2f420a9fed0d91a78a15a 458 SUPERFAMILY SSF88697 9 192 7.06E-33 T 23-10-2018 IPR015947 PUA-like superfamily VMUT_0492 df65d3b8cec2f420a9fed0d91a78a15a 458 SUPERFAMILY SSF52374 194 424 1.25E-63 T 23-10-2018 VMUT_0492 df65d3b8cec2f420a9fed0d91a78a15a 458 Gene3D G3DSA:3.40.50.620 197 423 1.4E-68 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_0492 df65d3b8cec2f420a9fed0d91a78a15a 458 Gene3D G3DSA:3.10.400.10 8 186 2.2E-32 T 23-10-2018 VMUT_0492 df65d3b8cec2f420a9fed0d91a78a15a 458 Pfam PF14306 PUA-like domain 9 187 1.3E-39 T 23-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 VMUT_0492 df65d3b8cec2f420a9fed0d91a78a15a 458 Pfam PF01747 ATP-sulfurylase 196 424 4.2E-73 T 23-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 VMUT_1542 caed79f922bd6a369c9a876bd72186ae 344 PRINTS PR00097 Anthranilate synthase component II signature 200 209 5.3E-7 T 23-10-2018 VMUT_1542 caed79f922bd6a369c9a876bd72186ae 344 PRINTS PR00097 Anthranilate synthase component II signature 228 239 5.3E-7 T 23-10-2018 VMUT_1542 caed79f922bd6a369c9a876bd72186ae 344 PRINTS PR00097 Anthranilate synthase component II signature 314 327 5.3E-7 T 23-10-2018 VMUT_1542 caed79f922bd6a369c9a876bd72186ae 344 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 343 38.637 T 23-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VMUT_1542 caed79f922bd6a369c9a876bd72186ae 344 SUPERFAMILY SSF52021 1 130 1.83E-46 T 23-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VMUT_1542 caed79f922bd6a369c9a876bd72186ae 344 SMART SM01097 1 119 3.6E-63 T 23-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VMUT_1542 caed79f922bd6a369c9a876bd72186ae 344 Gene3D G3DSA:3.40.50.880 135 341 1.9E-51 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like VMUT_1542 caed79f922bd6a369c9a876bd72186ae 344 Pfam PF00117 Glutamine amidotransferase class-I 162 337 4.1E-40 T 23-10-2018 IPR017926 Glutamine amidotransferase VMUT_1542 caed79f922bd6a369c9a876bd72186ae 344 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 1 118 2.8E-44 T 23-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VMUT_1542 caed79f922bd6a369c9a876bd72186ae 344 Gene3D G3DSA:3.50.30.20 1 133 6.8E-50 T 23-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VMUT_1542 caed79f922bd6a369c9a876bd72186ae 344 SUPERFAMILY SSF52317 134 342 2.66E-51 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like VMUT_1542 caed79f922bd6a369c9a876bd72186ae 344 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 1 339 2.7E-118 T 23-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VMUT_1542 caed79f922bd6a369c9a876bd72186ae 344 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 160 174 5.2E-32 T 23-10-2018 VMUT_1542 caed79f922bd6a369c9a876bd72186ae 344 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 245 262 5.2E-32 T 23-10-2018 VMUT_1542 caed79f922bd6a369c9a876bd72186ae 344 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 197 211 5.2E-32 T 23-10-2018 VMUT_1542 caed79f922bd6a369c9a876bd72186ae 344 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 228 244 5.2E-32 T 23-10-2018 VMUT_1542 caed79f922bd6a369c9a876bd72186ae 344 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 270 281 5.2E-32 T 23-10-2018 VMUT_1542 caed79f922bd6a369c9a876bd72186ae 344 PRINTS PR00096 Glutamine amidotransferase superfamily signature 314 327 1.6E-11 T 23-10-2018 VMUT_1542 caed79f922bd6a369c9a876bd72186ae 344 PRINTS PR00096 Glutamine amidotransferase superfamily signature 228 239 1.6E-11 T 23-10-2018 VMUT_1542 caed79f922bd6a369c9a876bd72186ae 344 PRINTS PR00096 Glutamine amidotransferase superfamily signature 200 209 1.6E-11 T 23-10-2018 VMUT_0036 7a4661e6c846da4717d9ea968ef10761 422 Gene3D G3DSA:3.40.630.10 9 211 5.8E-43 T 23-10-2018 VMUT_0036 7a4661e6c846da4717d9ea968ef10761 422 Gene3D G3DSA:3.40.630.10 315 422 2.3E-10 T 23-10-2018 VMUT_0036 7a4661e6c846da4717d9ea968ef10761 422 SUPERFAMILY SSF53187 4 420 9.69E-59 T 23-10-2018 VMUT_0036 7a4661e6c846da4717d9ea968ef10761 422 Pfam PF07687 Peptidase dimerisation domain 206 311 4.0E-16 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain VMUT_0036 7a4661e6c846da4717d9ea968ef10761 422 Pfam PF01546 Peptidase family M20/M25/M40 96 420 1.8E-34 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 VMUT_0036 7a4661e6c846da4717d9ea968ef10761 422 SUPERFAMILY SSF55031 210 326 2.99E-18 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VMUT_0036 7a4661e6c846da4717d9ea968ef10761 422 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 20 413 1.2E-77 T 23-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase VMUT_0036 7a4661e6c846da4717d9ea968ef10761 422 Gene3D G3DSA:3.30.70.360 212 314 6.4E-18 T 23-10-2018 VMUT_0901 c7e353d1146be1a597ec644ec5966c2e 294 Pfam PF13462 Thioredoxin 222 275 9.5E-9 T 23-10-2018 IPR012336 Thioredoxin-like fold VMUT_0901 c7e353d1146be1a597ec644ec5966c2e 294 Gene3D G3DSA:3.40.30.10 206 284 4.7E-9 T 23-10-2018 VMUT_0901 c7e353d1146be1a597ec644ec5966c2e 294 SUPERFAMILY SSF52833 219 273 6.4E-10 T 23-10-2018 IPR036249 Thioredoxin-like superfamily VMUT_1961 b1065b00d852cb64e6729c60fd4953ca 292 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 291 42.268 T 23-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VMUT_1961 b1065b00d852cb64e6729c60fd4953ca 292 SUPERFAMILY SSF51735 1 123 6.57E-41 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1961 b1065b00d852cb64e6729c60fd4953ca 292 Gene3D G3DSA:3.40.50.720 1 124 1.5E-52 T 23-10-2018 VMUT_1961 b1065b00d852cb64e6729c60fd4953ca 292 PRINTS PR01798 Succinyl-CoA synthase signature 243 260 3.8E-33 T 23-10-2018 VMUT_1961 b1065b00d852cb64e6729c60fd4953ca 292 PRINTS PR01798 Succinyl-CoA synthase signature 210 223 3.8E-33 T 23-10-2018 VMUT_1961 b1065b00d852cb64e6729c60fd4953ca 292 PRINTS PR01798 Succinyl-CoA synthase signature 179 197 3.8E-33 T 23-10-2018 VMUT_1961 b1065b00d852cb64e6729c60fd4953ca 292 PRINTS PR01798 Succinyl-CoA synthase signature 83 100 3.8E-33 T 23-10-2018 VMUT_1961 b1065b00d852cb64e6729c60fd4953ca 292 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 289 4.4E-121 T 23-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VMUT_1961 b1065b00d852cb64e6729c60fd4953ca 292 PIRSF PIRSF001553 1 292 1.6E-131 T 23-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VMUT_1961 b1065b00d852cb64e6729c60fd4953ca 292 Pfam PF00549 CoA-ligase 153 270 3.4E-16 T 23-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VMUT_1961 b1065b00d852cb64e6729c60fd4953ca 292 Gene3D G3DSA:3.40.50.261 125 291 1.6E-67 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VMUT_1961 b1065b00d852cb64e6729c60fd4953ca 292 SMART SM00881 4 101 2.3E-33 T 23-10-2018 IPR003781 CoA-binding GO:0048037 VMUT_1961 b1065b00d852cb64e6729c60fd4953ca 292 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 154 183 - T 23-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site VMUT_1961 b1065b00d852cb64e6729c60fd4953ca 292 SUPERFAMILY SSF52210 124 291 2.49E-48 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VMUT_1961 b1065b00d852cb64e6729c60fd4953ca 292 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 239 252 - T 23-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site VMUT_1961 b1065b00d852cb64e6729c60fd4953ca 292 Pfam PF02629 CoA binding domain 6 100 3.8E-30 T 23-10-2018 IPR003781 CoA-binding GO:0048037 VMUT_1830 0f46d58543ce47e3e8e4bf922a71246d 394 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 17 221 8.0E-18 T 23-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 VMUT_1830 0f46d58543ce47e3e8e4bf922a71246d 394 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 283 385 1.5E-10 T 23-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 VMUT_1830 0f46d58543ce47e3e8e4bf922a71246d 394 SUPERFAMILY SSF51726 19 391 7.46E-66 T 23-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 VMUT_1830 0f46d58543ce47e3e8e4bf922a71246d 394 Gene3D G3DSA:3.20.20.210 6 391 1.8E-89 T 23-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 VMUT_2083 6e288cdeb854999889ad3aba44159c51 553 Gene3D G3DSA:3.40.50.300 287 552 3.7E-70 T 23-10-2018 VMUT_2083 6e288cdeb854999889ad3aba44159c51 553 Pfam PF00005 ABC transporter 309 454 1.7E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_2083 6e288cdeb854999889ad3aba44159c51 553 Gene3D G3DSA:3.40.50.300 2 267 1.8E-61 T 23-10-2018 VMUT_2083 6e288cdeb854999889ad3aba44159c51 553 ProSitePatterns PS00211 ABC transporters family signature. 427 441 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VMUT_2083 6e288cdeb854999889ad3aba44159c51 553 SMART SM00382 31 228 5.2E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_2083 6e288cdeb854999889ad3aba44159c51 553 SMART SM00382 318 512 1.3E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_2083 6e288cdeb854999889ad3aba44159c51 553 Pfam PF00005 ABC transporter 22 173 1.4E-24 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_2083 6e288cdeb854999889ad3aba44159c51 553 SUPERFAMILY SSF52540 4 233 2.6E-54 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_2083 6e288cdeb854999889ad3aba44159c51 553 SUPERFAMILY SSF52540 288 518 1.46E-61 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_2083 6e288cdeb854999889ad3aba44159c51 553 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VMUT_0023 ba78467f5779d024423d723ee8aa26aa 285 PRINTS PR00412 Epoxide hydrolase signature 212 228 6.9E-7 T 23-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VMUT_0023 ba78467f5779d024423d723ee8aa26aa 285 PRINTS PR00412 Epoxide hydrolase signature 50 65 6.9E-7 T 23-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VMUT_0023 ba78467f5779d024423d723ee8aa26aa 285 PRINTS PR00412 Epoxide hydrolase signature 108 121 6.9E-7 T 23-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VMUT_0023 ba78467f5779d024423d723ee8aa26aa 285 PRINTS PR00412 Epoxide hydrolase signature 245 267 6.9E-7 T 23-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VMUT_0023 ba78467f5779d024423d723ee8aa26aa 285 SUPERFAMILY SSF53474 8 269 1.86E-60 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold VMUT_0023 ba78467f5779d024423d723ee8aa26aa 285 Gene3D G3DSA:3.40.50.1820 5 270 2.4E-60 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold VMUT_0023 ba78467f5779d024423d723ee8aa26aa 285 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 6.8E-7 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VMUT_0023 ba78467f5779d024423d723ee8aa26aa 285 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 6.8E-7 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VMUT_0023 ba78467f5779d024423d723ee8aa26aa 285 PRINTS PR00111 Alpha/beta hydrolase fold signature 214 228 6.8E-7 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VMUT_0023 ba78467f5779d024423d723ee8aa26aa 285 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 6.8E-7 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VMUT_0023 ba78467f5779d024423d723ee8aa26aa 285 Pfam PF12146 Serine aminopeptidase, S33 52 255 2.5E-21 T 23-10-2018 IPR022742 Serine aminopeptidase, S33 VMUT_0295 5105ea3428a38d58c716a325e8b9bcf8 559 SUPERFAMILY SSF48592 25 534 5.63E-93 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily VMUT_0295 5105ea3428a38d58c716a325e8b9bcf8 559 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 69 85 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 VMUT_0295 5105ea3428a38d58c716a325e8b9bcf8 559 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 97 105 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 VMUT_0295 5105ea3428a38d58c716a325e8b9bcf8 559 Gene3D G3DSA:3.50.7.10 225 376 9.4E-202 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily VMUT_0295 5105ea3428a38d58c716a325e8b9bcf8 559 SUPERFAMILY SSF54849 157 412 6.1E-27 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily VMUT_0295 5105ea3428a38d58c716a325e8b9bcf8 559 Pfam PF00118 TCP-1/cpn60 chaperonin family 43 535 7.0E-177 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 VMUT_0295 5105ea3428a38d58c716a325e8b9bcf8 559 Gene3D G3DSA:1.10.560.10 36 531 9.4E-202 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily VMUT_0295 5105ea3428a38d58c716a325e8b9bcf8 559 SUPERFAMILY SSF52029 220 386 5.65E-56 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily VMUT_0295 5105ea3428a38d58c716a325e8b9bcf8 559 Gene3D G3DSA:3.30.260.10 154 412 9.4E-202 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily VMUT_0295 5105ea3428a38d58c716a325e8b9bcf8 559 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 16 534 2.2E-231 T 23-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 VMUT_0295 5105ea3428a38d58c716a325e8b9bcf8 559 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 45 61 6.5E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 VMUT_0295 5105ea3428a38d58c716a325e8b9bcf8 559 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 97 116 6.5E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 VMUT_0295 5105ea3428a38d58c716a325e8b9bcf8 559 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 67 85 6.5E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 VMUT_0295 5105ea3428a38d58c716a325e8b9bcf8 559 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 415 427 6.5E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 VMUT_0295 5105ea3428a38d58c716a325e8b9bcf8 559 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 381 403 6.5E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 VMUT_0295 5105ea3428a38d58c716a325e8b9bcf8 559 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 48 60 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 VMUT_1848 82f51133b75c70443ddc226a40146b32 510 Gene3D G3DSA:3.30.110.30 433 510 6.7E-8 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 VMUT_1848 82f51133b75c70443ddc226a40146b32 510 Gene3D G3DSA:3.30.930.10 32 310 1.6E-88 T 23-10-2018 VMUT_1848 82f51133b75c70443ddc226a40146b32 510 Hamap MF_01571 Proline--tRNA ligase [proS]. 35 510 39.917 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 VMUT_1848 82f51133b75c70443ddc226a40146b32 510 SUPERFAMILY SSF52954 305 430 6.34E-36 T 23-10-2018 VMUT_1848 82f51133b75c70443ddc226a40146b32 510 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 128 299 1.2E-28 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_1848 82f51133b75c70443ddc226a40146b32 510 SMART SM00946 439 510 7.0E-13 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 VMUT_1848 82f51133b75c70443ddc226a40146b32 510 SUPERFAMILY SSF55681 40 304 3.45E-79 T 23-10-2018 VMUT_1848 82f51133b75c70443ddc226a40146b32 510 SUPERFAMILY SSF64586 434 510 1.16E-12 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 VMUT_1848 82f51133b75c70443ddc226a40146b32 510 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 440 510 3.6E-10 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 VMUT_1848 82f51133b75c70443ddc226a40146b32 510 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 37 510 3.4E-172 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 VMUT_1848 82f51133b75c70443ddc226a40146b32 510 Pfam PF03129 Anticodon binding domain 317 412 1.1E-20 T 23-10-2018 IPR004154 Anticodon-binding VMUT_1848 82f51133b75c70443ddc226a40146b32 510 Gene3D G3DSA:3.40.50.800 311 428 5.6E-38 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily VMUT_1848 82f51133b75c70443ddc226a40146b32 510 PRINTS PR01046 Prolyl-tRNA synthetase signature 133 144 8.2E-10 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 VMUT_1848 82f51133b75c70443ddc226a40146b32 510 PRINTS PR01046 Prolyl-tRNA synthetase signature 94 112 8.2E-10 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 VMUT_1848 82f51133b75c70443ddc226a40146b32 510 PRINTS PR01046 Prolyl-tRNA synthetase signature 173 184 8.2E-10 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 VMUT_1848 82f51133b75c70443ddc226a40146b32 510 PRINTS PR01046 Prolyl-tRNA synthetase signature 163 171 8.2E-10 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 VMUT_0462 4e1edc51b385e935c73a27afacf75672 160 SMART SM01413 3 141 1.8E-77 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0462 4e1edc51b385e935c73a27afacf75672 160 Gene3D G3DSA:1.10.10.2700 1 152 2.9E-51 T 23-10-2018 IPR038111 Ribosomal protein S19e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0462 4e1edc51b385e935c73a27afacf75672 160 Pfam PF01090 Ribosomal protein S19e 3 140 5.5E-49 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0462 4e1edc51b385e935c73a27afacf75672 160 ProDom PD003854 RIBOSOMAL 40S RIBONUCLEOPROTEIN S19 S19E 30S MULTIGENE FAMILY S19 SSU 3 120 7.0E-46 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0462 4e1edc51b385e935c73a27afacf75672 160 Hamap MF_01474 30S ribosomal protein S19e [rps19e]. 1 150 34.41 T 23-10-2018 IPR027548 Ribosomal protein S19e, archaeal GO:0003735|GO:0005840|GO:0006412 VMUT_0462 4e1edc51b385e935c73a27afacf75672 160 SUPERFAMILY SSF46785 2 152 5.99E-48 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0965 b1fb8ca3d7e7f52923a73ec9b3ce1a2d 122 Gene3D G3DSA:3.100.10.10 7 122 1.1E-33 T 23-10-2018 VMUT_0965 b1fb8ca3d7e7f52923a73ec9b3ce1a2d 122 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 46 103 1.2E-5 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P VMUT_0965 b1fb8ca3d7e7f52923a73ec9b3ce1a2d 122 SUPERFAMILY SSF52080 7 121 1.13E-23 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily VMUT_0965 b1fb8ca3d7e7f52923a73ec9b3ce1a2d 122 Hamap MF_00329 50S ribosomal protein L18e [rpl18e]. 6 122 26.897 T 23-10-2018 IPR022947 Ribosomal protein L18e, archaea VMUT_0965 b1fb8ca3d7e7f52923a73ec9b3ce1a2d 122 ProSitePatterns PS00475 Ribosomal protein L15 signature. 69 99 - T 23-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0625 da8c0504392dac34a51dfe066dba543a 529 Gene3D G3DSA:3.40.50.300 238 409 9.1E-22 T 23-10-2018 VMUT_0625 da8c0504392dac34a51dfe066dba543a 529 Pfam PF00437 Type II/IV secretion system protein 196 373 2.0E-11 T 23-10-2018 IPR001482 Type II/IV secretion system protein VMUT_0625 da8c0504392dac34a51dfe066dba543a 529 SMART SM00670 5 119 2.3E-4 T 23-10-2018 IPR002716 PIN domain VMUT_0625 da8c0504392dac34a51dfe066dba543a 529 SUPERFAMILY SSF88723 6 135 3.53E-9 T 23-10-2018 IPR029060 PIN-like domain superfamily VMUT_0625 da8c0504392dac34a51dfe066dba543a 529 SMART SM00382 261 396 1.5E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0625 da8c0504392dac34a51dfe066dba543a 529 SUPERFAMILY SSF52540 139 444 2.37E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0625 da8c0504392dac34a51dfe066dba543a 529 Gene3D G3DSA:3.40.50.1010 5 131 1.1E-18 T 23-10-2018 VMUT_0066 8ab9d441ad4eba264ca80368a2e954d6 338 Pfam PF00535 Glycosyl transferase family 2 5 118 1.1E-9 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VMUT_0066 8ab9d441ad4eba264ca80368a2e954d6 338 SUPERFAMILY SSF53448 3 295 9.9E-18 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0066 8ab9d441ad4eba264ca80368a2e954d6 338 Gene3D G3DSA:3.90.550.10 1 250 1.8E-21 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0787 2d5a5685e756e038d28d775e79812616 79 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 5 48 4.6E-15 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VMUT_0787 2d5a5685e756e038d28d775e79812616 79 SUPERFAMILY SSF89447 3 45 7.85E-13 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily VMUT_0787 2d5a5685e756e038d28d775e79812616 79 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 45 2.4E-16 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VMUT_0787 2d5a5685e756e038d28d775e79812616 79 SMART SM00966 5 50 2.4E-15 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VMUT_0787 2d5a5685e756e038d28d775e79812616 79 Gene3D G3DSA:2.10.260.10 1 43 1.8E-16 T 23-10-2018 VMUT_0803 59b1fd040ce6660190d27fab6123caaa 223 Pfam PF03070 TENA/THI-4/PQQC family 11 217 3.1E-47 T 23-10-2018 IPR004305 Thiaminase-2/PQQC VMUT_0803 59b1fd040ce6660190d27fab6123caaa 223 SUPERFAMILY SSF48613 6 219 3.86E-61 T 23-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 VMUT_0803 59b1fd040ce6660190d27fab6123caaa 223 Gene3D G3DSA:1.20.910.10 1 223 6.4E-60 T 23-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 VMUT_0803 59b1fd040ce6660190d27fab6123caaa 223 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 13 217 4.8E-43 T 23-10-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 VMUT_0958 cb0725bc69ad9ed0b6e435b05d3e1f80 332 Gene3D G3DSA:1.10.510.10 195 332 2.6E-24 T 23-10-2018 VMUT_0958 cb0725bc69ad9ed0b6e435b05d3e1f80 332 Gene3D G3DSA:3.30.200.20 98 194 4.8E-32 T 23-10-2018 VMUT_0958 cb0725bc69ad9ed0b6e435b05d3e1f80 332 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 226 237 - T 23-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 VMUT_0958 cb0725bc69ad9ed0b6e435b05d3e1f80 332 Pfam PF09202 Rio2, N-terminal 11 91 1.2E-22 T 23-10-2018 IPR015285 RIO2 kinase winged helix domain, N-terminal GO:0004674|GO:0005524|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 VMUT_0958 cb0725bc69ad9ed0b6e435b05d3e1f80 332 Pfam PF01163 RIO1 family 109 282 6.1E-45 T 23-10-2018 VMUT_0958 cb0725bc69ad9ed0b6e435b05d3e1f80 332 Gene3D G3DSA:1.10.10.10 4 93 1.2E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_0958 cb0725bc69ad9ed0b6e435b05d3e1f80 332 SUPERFAMILY SSF56112 101 276 1.99E-25 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily VMUT_0958 cb0725bc69ad9ed0b6e435b05d3e1f80 332 SUPERFAMILY SSF46785 6 92 2.49E-22 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0958 cb0725bc69ad9ed0b6e435b05d3e1f80 332 SMART SM00090 66 295 1.2E-58 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 VMUT_1026 5e1b2b7b5d8531bf6705c9ba07de17a9 225 SUPERFAMILY SSF51219 1 214 5.75E-57 T 23-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily VMUT_1026 5e1b2b7b5d8531bf6705c9ba07de17a9 225 Pfam PF01987 Mitochondrial biogenesis AIM24 4 204 4.7E-49 T 23-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 VMUT_1026 5e1b2b7b5d8531bf6705c9ba07de17a9 225 Gene3D G3DSA:3.60.160.10 1 222 2.4E-57 T 23-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily VMUT_1026 5e1b2b7b5d8531bf6705c9ba07de17a9 225 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 3 210 2.1E-33 T 23-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 VMUT_1114 772232a69059c0137db62b244950daba 219 Gene3D G3DSA:3.40.50.300 2 218 2.8E-64 T 23-10-2018 VMUT_1114 772232a69059c0137db62b244950daba 219 SMART SM00382 30 214 2.5E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_1114 772232a69059c0137db62b244950daba 219 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VMUT_1114 772232a69059c0137db62b244950daba 219 SUPERFAMILY SSF52540 6 215 1.63E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1114 772232a69059c0137db62b244950daba 219 Pfam PF00005 ABC transporter 21 167 1.2E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_0507 3c4f40258a53eaa4b00d16e63efc0e9c 82 SUPERFAMILY SSF46785 26 80 3.03E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0507 3c4f40258a53eaa4b00d16e63efc0e9c 82 Gene3D G3DSA:1.10.10.10 17 82 4.1E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_0222 c6d5c7b2334b2a2eba0e5e7c93f125dc 452 Pfam PF00919 Uncharacterized protein family UPF0004 4 98 1.9E-21 T 23-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 VMUT_0222 c6d5c7b2334b2a2eba0e5e7c93f125dc 452 Gene3D G3DSA:3.40.50.12160 4 127 1.9E-21 T 23-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily VMUT_0222 c6d5c7b2334b2a2eba0e5e7c93f125dc 452 SUPERFAMILY SSF102114 122 364 2.22E-46 T 23-10-2018 VMUT_0222 c6d5c7b2334b2a2eba0e5e7c93f125dc 452 Pfam PF04055 Radical SAM superfamily 141 318 2.4E-22 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_0222 c6d5c7b2334b2a2eba0e5e7c93f125dc 452 Gene3D G3DSA:3.80.30.20 135 373 1.4E-67 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe VMUT_0222 c6d5c7b2334b2a2eba0e5e7c93f125dc 452 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 426 1.7E-111 T 23-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 VMUT_0222 c6d5c7b2334b2a2eba0e5e7c93f125dc 452 SMART SM00729 137 359 2.1E-42 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VMUT_0222 c6d5c7b2334b2a2eba0e5e7c93f125dc 452 TIGRFAM TIGR01578 MiaB-like-B: MiaB-like tRNA modifying enzyme, archaeal-type 7 428 1.3E-103 T 23-10-2018 IPR006466 MiaB-like tRNA modifying enzyme, archaeal-type Reactome: R-HSA-6782315 VMUT_1171 b9b5ac9d8bfd2d5456f1e2085f93f7bb 314 TIGRFAM TIGR01230 agmatinase: agmatinase 34 302 1.5E-56 T 23-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 VMUT_1171 b9b5ac9d8bfd2d5456f1e2085f93f7bb 314 SUPERFAMILY SSF52768 3 307 4.86E-87 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily VMUT_1171 b9b5ac9d8bfd2d5456f1e2085f93f7bb 314 Pfam PF00491 Arginase family 32 300 2.9E-79 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 VMUT_1171 b9b5ac9d8bfd2d5456f1e2085f93f7bb 314 Gene3D G3DSA:3.40.800.10 1 313 1.4E-96 T 23-10-2018 VMUT_1171 b9b5ac9d8bfd2d5456f1e2085f93f7bb 314 PIRSF PIRSF036979 14 308 1.5E-86 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 VMUT_1171 b9b5ac9d8bfd2d5456f1e2085f93f7bb 314 ProSitePatterns PS01053 Arginase family signature. 230 251 - T 23-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 VMUT_1887 0d26d1053244688ec8798623c0119828 95 Pfam PF00248 Aldo/keto reductase family 15 66 2.0E-12 T 23-10-2018 IPR023210 NADP-dependent oxidoreductase domain VMUT_1887 0d26d1053244688ec8798623c0119828 95 SUPERFAMILY SSF51430 1 67 2.23E-21 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VMUT_1887 0d26d1053244688ec8798623c0119828 95 Gene3D G3DSA:3.20.20.100 1 85 2.1E-22 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VMUT_2072 de97a3d77106ce267e6598cb4aba2870 350 Gene3D G3DSA:3.30.1330.30 253 350 7.5E-23 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like VMUT_2072 de97a3d77106ce267e6598cb4aba2870 350 Hamap MF_01853 Protein pelota homolog [pelA]. 1 346 27.016 T 23-10-2018 IPR023521 Translation release factor pelota, archaea GO:0070481|GO:0070966|GO:0071025 VMUT_2072 de97a3d77106ce267e6598cb4aba2870 350 Gene3D G3DSA:3.30.420.60 129 247 8.3E-8 T 23-10-2018 VMUT_2072 de97a3d77106ce267e6598cb4aba2870 350 Pfam PF03465 eRF1 domain 3 255 346 2.8E-16 T 23-10-2018 IPR005142 eRF1 domain 3 VMUT_2072 de97a3d77106ce267e6598cb4aba2870 350 SUPERFAMILY SSF159065 6 108 1.07E-23 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain VMUT_2072 de97a3d77106ce267e6598cb4aba2870 350 SMART SM01194 1 121 2.4E-20 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like VMUT_2072 de97a3d77106ce267e6598cb4aba2870 350 SUPERFAMILY SSF55315 244 346 3.06E-22 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like VMUT_2072 de97a3d77106ce267e6598cb4aba2870 350 Gene3D G3DSA:2.30.30.870 1 122 2.6E-26 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain VMUT_2072 de97a3d77106ce267e6598cb4aba2870 350 Pfam PF03463 eRF1 domain 1 8 109 9.9E-14 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like VMUT_1143 c80595b754c749f096e82b050bacd4ae 415 SUPERFAMILY SSF69322 31 365 5.62E-28 T 23-10-2018 VMUT_1143 c80595b754c749f096e82b050bacd4ae 415 Gene3D G3DSA:2.130.10.10 236 380 1.9E-7 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 VMUT_1143 c80595b754c749f096e82b050bacd4ae 415 Gene3D G3DSA:2.130.10.10 11 235 2.2E-13 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 VMUT_1143 c80595b754c749f096e82b050bacd4ae 415 Pfam PF13360 PQQ-like domain 60 254 2.5E-7 T 23-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat VMUT_1641 e3bd7b6593e4fa109590b0082da16105 376 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 9 94 1.1E-6 T 23-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 VMUT_1641 e3bd7b6593e4fa109590b0082da16105 376 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 127 366 8.1E-24 T 23-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 VMUT_1641 e3bd7b6593e4fa109590b0082da16105 376 SUPERFAMILY SSF51735 10 166 4.68E-13 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1641 e3bd7b6593e4fa109590b0082da16105 376 Gene3D G3DSA:3.30.360.10 128 314 4.5E-84 T 23-10-2018 VMUT_1641 e3bd7b6593e4fa109590b0082da16105 376 Gene3D G3DSA:3.40.50.720 11 366 4.5E-84 T 23-10-2018 VMUT_1641 e3bd7b6593e4fa109590b0082da16105 376 SUPERFAMILY SSF55347 129 292 4.05E-23 T 23-10-2018 VMUT_0457 56e55863584c2d42013a7a787e92663c 369 SUPERFAMILY SSF161098 120 351 2.29E-6 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_0457 56e55863584c2d42013a7a787e92663c 369 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 144 368 1.7E-28 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VMUT_2077 32bb6a24c041488aee020691956c9e18 581 ProSitePatterns PS00150 Acylphosphatase signature 1. 501 511 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 VMUT_2077 32bb6a24c041488aee020691956c9e18 581 SUPERFAMILY SSF54975 494 581 4.14E-23 T 23-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 VMUT_2077 32bb6a24c041488aee020691956c9e18 581 Gene3D G3DSA:3.90.650.10 244 468 6.7E-12 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily VMUT_2077 32bb6a24c041488aee020691956c9e18 581 SUPERFAMILY SSF56042 275 462 3.07E-7 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily VMUT_2077 32bb6a24c041488aee020691956c9e18 581 Pfam PF00708 Acylphosphatase 498 580 5.4E-23 T 23-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 VMUT_2077 32bb6a24c041488aee020691956c9e18 581 ProSitePatterns PS00151 Acylphosphatase signature 2. 525 541 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 VMUT_2077 32bb6a24c041488aee020691956c9e18 581 Gene3D G3DSA:3.30.70.100 485 581 1.6E-25 T 23-10-2018 VMUT_1372 451e3fd53be73f3ffae6ae08af8d0a2d 566 Gene3D G3DSA:3.40.50.970 364 562 1.2E-48 T 23-10-2018 VMUT_1372 451e3fd53be73f3ffae6ae08af8d0a2d 566 SUPERFAMILY SSF52467 161 338 1.38E-46 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily VMUT_1372 451e3fd53be73f3ffae6ae08af8d0a2d 566 SUPERFAMILY SSF52518 4 190 7.25E-49 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold VMUT_1372 451e3fd53be73f3ffae6ae08af8d0a2d 566 Gene3D G3DSA:3.40.50.970 2 180 1.3E-54 T 23-10-2018 VMUT_1372 451e3fd53be73f3ffae6ae08af8d0a2d 566 SUPERFAMILY SSF52518 369 555 1.24E-46 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold VMUT_1372 451e3fd53be73f3ffae6ae08af8d0a2d 566 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 330 2.3E-38 T 23-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 VMUT_1372 451e3fd53be73f3ffae6ae08af8d0a2d 566 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 397 544 2.5E-35 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 VMUT_1372 451e3fd53be73f3ffae6ae08af8d0a2d 566 Gene3D G3DSA:3.40.50.1220 191 359 7.6E-48 T 23-10-2018 VMUT_1372 451e3fd53be73f3ffae6ae08af8d0a2d 566 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 177 1.1E-49 T 23-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 VMUT_0714 7b7b2fe5183301ce4908283b4b21a792 447 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 7 394 2.9E-95 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 VMUT_0714 7b7b2fe5183301ce4908283b4b21a792 447 Gene3D G3DSA:3.40.1670.10 306 421 1.5E-36 T 23-10-2018 VMUT_0714 7b7b2fe5183301ce4908283b4b21a792 447 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 3 421 2.5E-96 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 VMUT_0714 7b7b2fe5183301ce4908283b4b21a792 447 SUPERFAMILY SSF50475 1 280 2.28E-65 T 23-10-2018 VMUT_0714 7b7b2fe5183301ce4908283b4b21a792 447 SUPERFAMILY SSF143968 292 428 2.09E-41 T 23-10-2018 VMUT_0412 31d53a842aa2d202ed09c7a4bcad7331 474 Pfam PF16561 Glycogen recognition site of AMP-activated protein kinase 26 73 1.0E-6 T 23-10-2018 IPR032640 AMP-activated protein kinase, glycogen-binding domain Reactome: R-HSA-1445148|Reactome: R-HSA-1632852|Reactome: R-HSA-2151209|Reactome: R-HSA-380972|Reactome: R-HSA-5628897|Reactome: R-HSA-6804756 VMUT_0412 31d53a842aa2d202ed09c7a4bcad7331 474 SUPERFAMILY SSF51445 48 427 2.77E-74 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily VMUT_0412 31d53a842aa2d202ed09c7a4bcad7331 474 SMART SM00642 105 428 1.4E-58 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 VMUT_0412 31d53a842aa2d202ed09c7a4bcad7331 474 Gene3D G3DSA:2.60.40.10 9 87 3.8E-8 T 23-10-2018 IPR013783 Immunoglobulin-like fold VMUT_0412 31d53a842aa2d202ed09c7a4bcad7331 474 Gene3D G3DSA:3.20.20.80 103 427 2.5E-85 T 23-10-2018 VMUT_0412 31d53a842aa2d202ed09c7a4bcad7331 474 Pfam PF00128 Alpha amylase, catalytic domain 228 399 6.6E-13 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 VMUT_0412 31d53a842aa2d202ed09c7a4bcad7331 474 Pfam PF00128 Alpha amylase, catalytic domain 125 224 2.7E-28 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 VMUT_0412 31d53a842aa2d202ed09c7a4bcad7331 474 Gene3D G3DSA:3.90.400.10 198 241 2.5E-85 T 23-10-2018 VMUT_1159 ee508cc2c0009ee7de89dbed0e635abd 463 PIRSF PIRSF006060 1 462 1.5E-61 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_1159 ee508cc2c0009ee7de89dbed0e635abd 463 Pfam PF00324 Amino acid permease 37 427 6.0E-23 T 23-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 VMUT_1159 ee508cc2c0009ee7de89dbed0e635abd 463 Gene3D G3DSA:1.20.1740.10 12 454 7.0E-33 T 23-10-2018 VMUT_1639 44351ae273cb2aee301cae1774766885 108 Gene3D G3DSA:2.10.260.10 10 97 6.2E-13 T 23-10-2018 VMUT_0830 097d0181df1d58b2be6d4fc1789d9636 188 SUPERFAMILY SSF52499 6 184 1.22E-39 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VMUT_0830 097d0181df1d58b2be6d4fc1789d9636 188 Pfam PF00857 Isochorismatase family 16 181 1.6E-33 T 23-10-2018 IPR000868 Isochorismatase-like GO:0003824 VMUT_0830 097d0181df1d58b2be6d4fc1789d9636 188 Gene3D G3DSA:3.40.50.850 4 184 7.3E-36 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VMUT_0387 1c65678c55b2ddb8a7905573bf4b3f64 151 Pfam PF03684 Uncharacterised protein family (UPF0179) 8 143 1.0E-29 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 VMUT_0387 1c65678c55b2ddb8a7905573bf4b3f64 151 ProDom PD016182 UPF0179 TK0790 TV1250 PAE0681 PF1381 AF2154 MA3685 VNG1401C MJ1627 PH1477 7 146 7.0E-19 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 VMUT_0720 606f6677c0e5f0b21ba6b5da11dfe186 174 Pfam PF01965 DJ-1/PfpI family 1 164 8.5E-8 T 23-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 VMUT_0720 606f6677c0e5f0b21ba6b5da11dfe186 174 SUPERFAMILY SSF52317 1 159 8.78E-14 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like VMUT_0720 606f6677c0e5f0b21ba6b5da11dfe186 174 Gene3D G3DSA:3.40.50.880 1 172 2.0E-17 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like VMUT_1562 a7585c38b836de4e853083848ff2df2d 146 Pfam PF00571 CBS domain 77 121 2.1E-8 T 23-10-2018 IPR000644 CBS domain VMUT_1562 a7585c38b836de4e853083848ff2df2d 146 Pfam PF00571 CBS domain 7 60 4.1E-11 T 23-10-2018 IPR000644 CBS domain VMUT_1562 a7585c38b836de4e853083848ff2df2d 146 Gene3D G3DSA:3.10.580.10 1 137 2.5E-34 T 23-10-2018 VMUT_1562 a7585c38b836de4e853083848ff2df2d 146 SMART SM00116 77 124 1.8E-9 T 23-10-2018 IPR000644 CBS domain VMUT_1562 a7585c38b836de4e853083848ff2df2d 146 SMART SM00116 12 60 2.6E-10 T 23-10-2018 IPR000644 CBS domain VMUT_1562 a7585c38b836de4e853083848ff2df2d 146 SUPERFAMILY SSF54631 4 121 6.95E-31 T 23-10-2018 VMUT_1189 5933a13605d4c35424c46d8b3d97a4ac 46 Pfam PF04758 Ribosomal protein S30 1 38 5.5E-6 T 23-10-2018 IPR006846 Ribosomal protein S30 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1164 f50bcf1fd2b2fcb7cc077f9282510af7 282 SUPERFAMILY SSF50447 120 198 8.33E-12 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VMUT_1164 f50bcf1fd2b2fcb7cc077f9282510af7 282 Gene3D G3DSA:2.40.30.10 125 203 6.3E-13 T 23-10-2018 VMUT_2321 d4fa525668462338191001908eb3a184 329 Gene3D G3DSA:3.40.50.150 6 308 6.0E-65 T 23-10-2018 VMUT_2321 d4fa525668462338191001908eb3a184 329 Gene3D G3DSA:3.90.120.10 156 302 6.0E-65 T 23-10-2018 VMUT_2321 d4fa525668462338191001908eb3a184 329 SUPERFAMILY SSF53335 1 311 7.14E-78 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_2321 d4fa525668462338191001908eb3a184 329 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 117 131 2.1E-12 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 VMUT_2321 d4fa525668462338191001908eb3a184 329 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 161 174 2.1E-12 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 VMUT_2321 d4fa525668462338191001908eb3a184 329 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 4 20 2.1E-12 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 VMUT_2321 d4fa525668462338191001908eb3a184 329 Pfam PF00145 C-5 cytosine-specific DNA methylase 251 311 5.4E-13 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 VMUT_2321 d4fa525668462338191001908eb3a184 329 Pfam PF00145 C-5 cytosine-specific DNA methylase 3 172 4.6E-34 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 VMUT_2321 d4fa525668462338191001908eb3a184 329 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 5 171 6.9E-32 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 VMUT_0605 90b45d4f426ac14b5a4af597e5ee62c7 500 Gene3D G3DSA:3.40.605.10 44 495 2.2E-137 T 23-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VMUT_0605 90b45d4f426ac14b5a4af597e5ee62c7 500 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 273 280 - T 23-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 VMUT_0605 90b45d4f426ac14b5a4af597e5ee62c7 500 Gene3D G3DSA:3.40.309.10 280 467 2.2E-137 T 23-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VMUT_0605 90b45d4f426ac14b5a4af597e5ee62c7 500 SUPERFAMILY SSF53720 26 498 4.32E-136 T 23-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VMUT_0605 90b45d4f426ac14b5a4af597e5ee62c7 500 Pfam PF00171 Aldehyde dehydrogenase family 44 495 9.8E-135 T 23-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VMUT_0007 61a5ee69ed08644a7664d294754e3eb2 337 Gene3D G3DSA:3.60.15.10 6 261 4.6E-50 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_0007 61a5ee69ed08644a7664d294754e3eb2 337 SMART SM00849 25 234 3.2E-23 T 23-10-2018 IPR001279 Metallo-beta-lactamase VMUT_0007 61a5ee69ed08644a7664d294754e3eb2 337 Pfam PF00753 Metallo-beta-lactamase superfamily 23 234 3.7E-24 T 23-10-2018 IPR001279 Metallo-beta-lactamase VMUT_0007 61a5ee69ed08644a7664d294754e3eb2 337 SUPERFAMILY SSF56281 7 307 7.08E-44 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_1581 a2caf8f7d5f8120ceebf674a01ef6034 416 SUPERFAMILY SSF54826 4 127 1.86E-35 T 23-10-2018 VMUT_1581 a2caf8f7d5f8120ceebf674a01ef6034 416 SUPERFAMILY SSF51604 127 406 4.45E-83 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VMUT_1581 a2caf8f7d5f8120ceebf674a01ef6034 416 Pfam PF00113 Enolase, C-terminal TIM barrel domain 130 407 4.1E-62 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VMUT_1581 a2caf8f7d5f8120ceebf674a01ef6034 416 ProSitePatterns PS00164 Enolase signature. 324 337 - T 23-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VMUT_1581 a2caf8f7d5f8120ceebf674a01ef6034 416 Gene3D G3DSA:3.30.390.10 1 114 4.7E-29 T 23-10-2018 IPR029017 Enolase-like, N-terminal VMUT_1581 a2caf8f7d5f8120ceebf674a01ef6034 416 SMART SM01192 127 407 1.3E-111 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VMUT_1581 a2caf8f7d5f8120ceebf674a01ef6034 416 PRINTS PR00148 Enolase signature 33 47 5.7E-26 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VMUT_1581 a2caf8f7d5f8120ceebf674a01ef6034 416 PRINTS PR00148 Enolase signature 353 370 5.7E-26 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VMUT_1581 a2caf8f7d5f8120ceebf674a01ef6034 416 PRINTS PR00148 Enolase signature 150 163 5.7E-26 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VMUT_1581 a2caf8f7d5f8120ceebf674a01ef6034 416 PRINTS PR00148 Enolase signature 95 111 5.7E-26 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VMUT_1581 a2caf8f7d5f8120ceebf674a01ef6034 416 PRINTS PR00148 Enolase signature 324 338 5.7E-26 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VMUT_1581 a2caf8f7d5f8120ceebf674a01ef6034 416 PRINTS PR00148 Enolase signature 301 312 5.7E-26 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VMUT_1581 a2caf8f7d5f8120ceebf674a01ef6034 416 SMART SM01193 1 122 8.6E-44 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VMUT_1581 a2caf8f7d5f8120ceebf674a01ef6034 416 PIRSF PIRSF001400 1 413 5.4E-139 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VMUT_1581 a2caf8f7d5f8120ceebf674a01ef6034 416 Gene3D G3DSA:3.20.20.120 117 415 7.7E-87 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VMUT_1581 a2caf8f7d5f8120ceebf674a01ef6034 416 Hamap MF_00318 Enolase [eno]. 1 400 35.862 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VMUT_1581 a2caf8f7d5f8120ceebf674a01ef6034 416 Pfam PF03952 Enolase, N-terminal domain 3 122 1.3E-32 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VMUT_0566 6fe7d1a7b15ca343f9ab5126b3f86059 221 Gene3D G3DSA:1.10.3480.10 11 218 3.8E-20 T 23-10-2018 VMUT_0566 6fe7d1a7b15ca343f9ab5126b3f86059 221 Pfam PF02613 Nitrate reductase delta subunit 65 181 7.2E-13 T 23-10-2018 IPR020945 DMSO/Nitrate reductase chaperone VMUT_0566 6fe7d1a7b15ca343f9ab5126b3f86059 221 SUPERFAMILY SSF89155 15 211 1.96E-21 T 23-10-2018 IPR036411 TorD-like superfamily VMUT_1714 6ff5b467c5f249e408e891e46bda8c3d 219 Gene3D G3DSA:3.40.50.2000 39 207 2.7E-24 T 23-10-2018 VMUT_1714 6ff5b467c5f249e408e891e46bda8c3d 219 Pfam PF00534 Glycosyl transferases group 1 33 188 5.0E-17 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 VMUT_1714 6ff5b467c5f249e408e891e46bda8c3d 219 SUPERFAMILY SSF53756 17 217 6.28E-29 T 23-10-2018 VMUT_0636 8c5319b398f6547bee218a33170621f5 184 Gene3D G3DSA:3.40.920.10 1 181 2.2E-41 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 VMUT_0636 8c5319b398f6547bee218a33170621f5 184 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 4 174 1.1E-29 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 VMUT_0636 8c5319b398f6547bee218a33170621f5 184 SUPERFAMILY SSF53323 2 178 3.92E-31 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 VMUT_0371 46c2a1efd02b298d6c8dcab3a3534e94 201 SUPERFAMILY SSF49777 53 199 2.62E-33 T 23-10-2018 IPR036610 PEBP-like superfamily VMUT_0371 46c2a1efd02b298d6c8dcab3a3534e94 201 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 69 177 5.4E-26 T 23-10-2018 IPR005247 YbhB/YbcL VMUT_0371 46c2a1efd02b298d6c8dcab3a3534e94 201 Pfam PF01161 Phosphatidylethanolamine-binding protein 64 199 1.4E-25 T 23-10-2018 IPR008914 Phosphatidylethanolamine-binding protein VMUT_0371 46c2a1efd02b298d6c8dcab3a3534e94 201 Gene3D G3DSA:3.90.280.10 45 200 1.6E-38 T 23-10-2018 IPR036610 PEBP-like superfamily VMUT_1076 0471bb927868a1739490c77f65c48d47 334 Pfam PF00535 Glycosyl transferase family 2 8 122 3.8E-20 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VMUT_1076 0471bb927868a1739490c77f65c48d47 334 Gene3D G3DSA:3.90.550.10 5 225 9.9E-30 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1076 0471bb927868a1739490c77f65c48d47 334 SUPERFAMILY SSF53448 9 254 9.19E-38 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_2265 11682e3884f72b097cc82bf014c20571 350 Pfam PF01137 RNA 3'-terminal phosphate cyclase 11 335 5.0E-84 T 23-10-2018 IPR023797 RNA 3'-terminal phosphate cyclase domain VMUT_2265 11682e3884f72b097cc82bf014c20571 350 SUPERFAMILY SSF55205 279 341 8.5E-7 T 23-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 VMUT_2265 11682e3884f72b097cc82bf014c20571 350 Pfam PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain 181 283 4.5E-28 T 23-10-2018 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain VMUT_2265 11682e3884f72b097cc82bf014c20571 350 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 4 334 2.5E-134 T 23-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 VMUT_2265 11682e3884f72b097cc82bf014c20571 350 PIRSF PIRSF005378 1 348 2.5E-121 T 23-10-2018 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 VMUT_2265 11682e3884f72b097cc82bf014c20571 350 Gene3D G3DSA:3.65.10.20 5 329 1.3E-122 T 23-10-2018 IPR037136 RNA 3'-terminal phosphate cyclase domain superfamily VMUT_2265 11682e3884f72b097cc82bf014c20571 350 Gene3D G3DSA:3.30.360.20 183 284 1.3E-122 T 23-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily VMUT_2265 11682e3884f72b097cc82bf014c20571 350 SUPERFAMILY SSF55205 3 235 2.55E-69 T 23-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 VMUT_2265 11682e3884f72b097cc82bf014c20571 350 Hamap MF_00200 RNA 3'-terminal phosphate cyclase [rtcA]. 3 347 41.227 T 23-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 VMUT_2265 11682e3884f72b097cc82bf014c20571 350 ProSitePatterns PS01287 RNA 3'-terminal phosphate cyclase signature. 156 166 - T 23-10-2018 IPR020719 RNA 3'-terminal phosphate cyclase-like, conserved site VMUT_0441 4dfbdb78734c93a27c454d3914c4cf50 351 SUPERFAMILY SSF50129 10 193 3.8E-36 T 23-10-2018 IPR011032 GroES-like superfamily VMUT_0441 4dfbdb78734c93a27c454d3914c4cf50 351 SUPERFAMILY SSF51735 172 303 3.73E-16 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0441 4dfbdb78734c93a27c454d3914c4cf50 351 Hamap MF_02127 Glucose 1-dehydrogenase [gdh]. 1 349 63.562 T 23-10-2018 IPR026583 Glucose 1-dehydrogenase GO:0005536|GO:0008270|GO:0047936 KEGG: 00030+1.1.1.47 VMUT_0441 4dfbdb78734c93a27c454d3914c4cf50 351 Pfam PF16912 Glucose dehydrogenase C-terminus 143 348 9.3E-63 T 23-10-2018 IPR031640 Glucose dehydrogenase, C-terminal KEGG: 00030+1.1.1.47 VMUT_0441 4dfbdb78734c93a27c454d3914c4cf50 351 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 137 1.6E-12 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VMUT_0441 4dfbdb78734c93a27c454d3914c4cf50 351 Gene3D G3DSA:3.40.50.720 145 322 4.1E-91 T 23-10-2018 VMUT_0441 4dfbdb78734c93a27c454d3914c4cf50 351 Gene3D G3DSA:3.90.180.10 16 346 4.1E-91 T 23-10-2018 VMUT_0343 9fc81fceaded61eff602393ac33c4135 144 SMART SM01374 21 144 6.3E-52 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 VMUT_0343 9fc81fceaded61eff602393ac33c4135 144 ProSitePatterns PS00049 Ribosomal protein L14 signature. 83 109 - T 23-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0343 9fc81fceaded61eff602393ac33c4135 144 Pfam PF00238 Ribosomal protein L14p/L23e 22 143 1.5E-32 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 VMUT_0343 9fc81fceaded61eff602393ac33c4135 144 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 21 144 19.455 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 VMUT_0343 9fc81fceaded61eff602393ac33c4135 144 Gene3D G3DSA:2.40.150.20 1 144 7.9E-45 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 VMUT_0343 9fc81fceaded61eff602393ac33c4135 144 SUPERFAMILY SSF50193 15 144 3.27E-39 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 VMUT_0270 da8b4fdb41c49113cb6b61f76579199a 422 Gene3D G3DSA:3.90.600.20 161 253 2.8E-19 T 23-10-2018 VMUT_0270 da8b4fdb41c49113cb6b61f76579199a 422 Hamap MF_01892 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS [tiaS]. 4 413 26.841 T 23-10-2018 IPR024913 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS GO:0002101|GO:0016879 VMUT_0270 da8b4fdb41c49113cb6b61f76579199a 422 Gene3D G3DSA:3.30.70.2200 3 158 2.3E-42 T 23-10-2018 VMUT_0270 da8b4fdb41c49113cb6b61f76579199a 422 Pfam PF08489 Domain of unknown function (DUF1743) 145 254 7.5E-26 T 23-10-2018 IPR013696 Domain of unknown function DUF1743 VMUT_0270 da8b4fdb41c49113cb6b61f76579199a 422 Gene3D G3DSA:2.40.50.1010 254 383 1.1E-13 T 23-10-2018 VMUT_1222 0ab0d3df5ba0a5844ed3311231a0330b 136 SMART SM00960 21 109 3.7E-14 T 23-10-2018 IPR004942 Roadblock/LAMTOR2 domain VMUT_1222 0ab0d3df5ba0a5844ed3311231a0330b 136 Pfam PF03259 Roadblock/LC7 domain 24 104 2.1E-10 T 23-10-2018 IPR004942 Roadblock/LAMTOR2 domain VMUT_1222 0ab0d3df5ba0a5844ed3311231a0330b 136 Gene3D G3DSA:3.30.450.30 16 136 5.7E-20 T 23-10-2018 VMUT_1222 0ab0d3df5ba0a5844ed3311231a0330b 136 SUPERFAMILY SSF103196 17 132 2.09E-16 T 23-10-2018 VMUT_1242 274b3252f1b4a973a64e0ffb0af79e2a 606 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 8 207 2.2E-68 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_1242 274b3252f1b4a973a64e0ffb0af79e2a 606 SMART SM00790 6 208 2.1E-86 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_1242 274b3252f1b4a973a64e0ffb0af79e2a 606 SUPERFAMILY SSF56228 4 210 3.53E-64 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily VMUT_1242 274b3252f1b4a973a64e0ffb0af79e2a 606 SUPERFAMILY SSF48310 213 601 1.44E-101 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_1242 274b3252f1b4a973a64e0ffb0af79e2a 606 Gene3D G3DSA:1.10.599.10 240 602 1.4E-114 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 VMUT_1242 274b3252f1b4a973a64e0ffb0af79e2a 606 Gene3D G3DSA:3.60.9.10 2 212 3.2E-74 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily VMUT_1242 274b3252f1b4a973a64e0ffb0af79e2a 606 Gene3D G3DSA:1.10.569.10 242 433 1.4E-114 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 VMUT_1242 274b3252f1b4a973a64e0ffb0af79e2a 606 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 223 602 1.3E-111 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_0092 8750f8aa43922bd082f0a753e57f3bca 159 TIGRFAM TIGR01080 rplX_A_E: ribosomal protein uL24 7 120 4.8E-47 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0092 8750f8aa43922bd082f0a753e57f3bca 159 ProSitePatterns PS01108 Ribosomal protein L24 signature. 51 68 - T 23-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_0092 8750f8aa43922bd082f0a753e57f3bca 159 SUPERFAMILY SSF50104 7 116 3.1E-33 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily VMUT_0092 8750f8aa43922bd082f0a753e57f3bca 159 Pfam PF16906 Ribosomal proteins L26 eukaryotic, L24P archaeal 7 120 2.3E-29 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0092 8750f8aa43922bd082f0a753e57f3bca 159 Hamap MF_01326_A 50S ribosomal protein L24 [rplX]. 7 120 29.983 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0092 8750f8aa43922bd082f0a753e57f3bca 159 Pfam PF00467 KOW motif 50 81 3.9E-7 T 23-10-2018 IPR005824 KOW VMUT_0092 8750f8aa43922bd082f0a753e57f3bca 159 SMART SM00739 47 74 1.5E-5 T 23-10-2018 IPR005824 KOW VMUT_0092 8750f8aa43922bd082f0a753e57f3bca 159 Gene3D G3DSA:2.30.30.30 2 143 1.3E-44 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 VMUT_2313 78e716d65edea47e44337a48331c4caf 398 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 95 120 - T 23-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 VMUT_2313 78e716d65edea47e44337a48331c4caf 398 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 27 120 6.0E-16 T 23-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain VMUT_2313 78e716d65edea47e44337a48331c4caf 398 SMART SM00922 141 247 1.1E-21 T 23-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal VMUT_2313 78e716d65edea47e44337a48331c4caf 398 SUPERFAMILY SSF51604 108 376 5.01E-75 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VMUT_2313 78e716d65edea47e44337a48331c4caf 398 Pfam PF13378 Enolase C-terminal domain-like 144 368 2.1E-61 T 23-10-2018 IPR029065 Enolase C-terminal domain-like VMUT_2313 78e716d65edea47e44337a48331c4caf 398 SUPERFAMILY SSF54826 3 125 2.06E-27 T 23-10-2018 VMUT_2313 78e716d65edea47e44337a48331c4caf 398 Gene3D G3DSA:3.20.20.120 113 360 1.3E-112 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VMUT_2313 78e716d65edea47e44337a48331c4caf 398 Gene3D G3DSA:3.30.390.10 27 370 1.3E-112 T 23-10-2018 IPR029017 Enolase-like, N-terminal VMUT_2136 6cf1298a8a19a8a4e0a2ceaa4699d7c2 171 Gene3D G3DSA:1.10.10.10 3 54 7.5E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_2136 6cf1298a8a19a8a4e0a2ceaa4699d7c2 171 SUPERFAMILY SSF46785 2 63 2.69E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_2136 6cf1298a8a19a8a4e0a2ceaa4699d7c2 171 Gene3D G3DSA:3.30.70.920 56 150 1.9E-25 T 23-10-2018 VMUT_2136 6cf1298a8a19a8a4e0a2ceaa4699d7c2 171 SMART SM00344 3 123 7.5E-23 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 VMUT_2136 6cf1298a8a19a8a4e0a2ceaa4699d7c2 171 SUPERFAMILY SSF54909 101 155 1.34E-12 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel VMUT_2136 6cf1298a8a19a8a4e0a2ceaa4699d7c2 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 7.4E-8 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VMUT_2136 6cf1298a8a19a8a4e0a2ceaa4699d7c2 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 7.4E-8 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VMUT_2136 6cf1298a8a19a8a4e0a2ceaa4699d7c2 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 7.4E-8 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VMUT_2136 6cf1298a8a19a8a4e0a2ceaa4699d7c2 171 Pfam PF01037 Lrp/AsnC ligand binding domain 70 153 8.8E-16 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain VMUT_2136 6cf1298a8a19a8a4e0a2ceaa4699d7c2 171 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 1.1E-9 T 23-10-2018 VMUT_1943 c4905b4ee47c2cea86004a193c445fe5 90 Gene3D G3DSA:3.30.1280.10 3 88 1.1E-21 T 23-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 VMUT_1943 c4905b4ee47c2cea86004a193c445fe5 90 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 10 82 1.2E-13 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 VMUT_1943 c4905b4ee47c2cea86004a193c445fe5 90 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 17 80 0.001 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 VMUT_1943 c4905b4ee47c2cea86004a193c445fe5 90 SUPERFAMILY SSF82697 8 82 2.44E-10 T 23-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 VMUT_2341 2ae1df1f13e6879679d957e047958364 656 Gene3D G3DSA:3.50.50.60 496 562 1.1E-5 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_2341 2ae1df1f13e6879679d957e047958364 656 SUPERFAMILY SSF54862 565 639 3.09E-21 T 23-10-2018 VMUT_2341 2ae1df1f13e6879679d957e047958364 656 Pfam PF12838 4Fe-4S dicluster domain 585 633 1.8E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_2341 2ae1df1f13e6879679d957e047958364 656 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 619 630 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_2341 2ae1df1f13e6879679d957e047958364 656 SUPERFAMILY SSF51905 149 568 1.53E-23 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_2341 2ae1df1f13e6879679d957e047958364 656 Gene3D G3DSA:3.50.50.60 407 495 1.1E-5 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_2341 2ae1df1f13e6879679d957e047958364 656 Pfam PF12831 FAD dependent oxidoreductase 149 217 6.1E-10 T 23-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal VMUT_2341 2ae1df1f13e6879679d957e047958364 656 Gene3D G3DSA:3.30.70.20 578 638 2.7E-14 T 23-10-2018 VMUT_2341 2ae1df1f13e6879679d957e047958364 656 Gene3D G3DSA:3.50.50.60 144 252 3.0E-15 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_2188 a05e8c3dd6323dadfc4adb55000c7a81 324 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 321 8.6E-27 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VMUT_2188 a05e8c3dd6323dadfc4adb55000c7a81 324 Pfam PF00005 ABC transporter 23 187 1.2E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_2188 a05e8c3dd6323dadfc4adb55000c7a81 324 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 302 1.8E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VMUT_2188 a05e8c3dd6323dadfc4adb55000c7a81 324 Gene3D G3DSA:3.40.50.300 1 324 6.1E-95 T 23-10-2018 VMUT_2188 a05e8c3dd6323dadfc4adb55000c7a81 324 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VMUT_2188 a05e8c3dd6323dadfc4adb55000c7a81 324 SUPERFAMILY SSF52540 32 316 2.22E-64 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_2188 a05e8c3dd6323dadfc4adb55000c7a81 324 SMART SM00382 32 244 7.8E-18 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_1607 2d18a7cffd008024726373692561fc0e 187 Pfam PF02834 LigT like Phosphoesterase 12 94 8.1E-20 T 23-10-2018 IPR014051 Phosphoesterase, HXTX VMUT_1607 2d18a7cffd008024726373692561fc0e 187 Pfam PF02834 LigT like Phosphoesterase 98 178 5.5E-7 T 23-10-2018 IPR014051 Phosphoesterase, HXTX VMUT_1607 2d18a7cffd008024726373692561fc0e 187 SUPERFAMILY SSF55144 6 186 3.84E-43 T 23-10-2018 IPR009097 Cyclic phosphodiesterase VMUT_1607 2d18a7cffd008024726373692561fc0e 187 Gene3D G3DSA:3.90.1140.10 6 187 8.9E-53 T 23-10-2018 VMUT_1607 2d18a7cffd008024726373692561fc0e 187 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 6 186 25.944 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 VMUT_1607 2d18a7cffd008024726373692561fc0e 187 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 7 186 4.1E-49 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 VMUT_1576 68fddc80b52156d27aedaeffbe159cd4 184 Gene3D G3DSA:3.40.50.300 3 177 3.3E-39 T 23-10-2018 VMUT_1576 68fddc80b52156d27aedaeffbe159cd4 184 TIGRFAM TIGR02173 cyt_kin_arch: putative cytidylate kinase 6 174 3.8E-53 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 VMUT_1576 68fddc80b52156d27aedaeffbe159cd4 184 Hamap MF_00239 Cytidylate kinase [cmk]. 5 178 40.481 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 VMUT_1576 68fddc80b52156d27aedaeffbe159cd4 184 SUPERFAMILY SSF52540 6 177 9.0E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1576 68fddc80b52156d27aedaeffbe159cd4 184 Pfam PF13189 Cytidylate kinase-like family 6 159 9.3E-21 T 23-10-2018 VMUT_1551 983d075157b8a51621ec75a0f94d99e2 444 SUPERFAMILY SSF50447 233 329 4.37E-30 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VMUT_1551 983d075157b8a51621ec75a0f94d99e2 444 Gene3D G3DSA:3.40.50.300 5 232 1.4E-88 T 23-10-2018 VMUT_1551 983d075157b8a51621ec75a0f94d99e2 444 Pfam PF03144 Elongation factor Tu domain 2 255 321 1.9E-17 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 VMUT_1551 983d075157b8a51621ec75a0f94d99e2 444 SUPERFAMILY SSF52540 13 256 7.17E-78 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1551 983d075157b8a51621ec75a0f94d99e2 444 Pfam PF03143 Elongation factor Tu C-terminal domain 329 435 1.5E-34 T 23-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal VMUT_1551 983d075157b8a51621ec75a0f94d99e2 444 Hamap MF_00118_A Elongation factor Tu [tuf]. 11 438 60.041 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 VMUT_1551 983d075157b8a51621ec75a0f94d99e2 444 PRINTS PR00315 GTP-binding elongation factor signature 18 31 6.6E-21 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VMUT_1551 983d075157b8a51621ec75a0f94d99e2 444 PRINTS PR00315 GTP-binding elongation factor signature 97 107 6.6E-21 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VMUT_1551 983d075157b8a51621ec75a0f94d99e2 444 PRINTS PR00315 GTP-binding elongation factor signature 157 166 6.6E-21 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VMUT_1551 983d075157b8a51621ec75a0f94d99e2 444 PRINTS PR00315 GTP-binding elongation factor signature 113 124 6.6E-21 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VMUT_1551 983d075157b8a51621ec75a0f94d99e2 444 PRINTS PR00315 GTP-binding elongation factor signature 77 85 6.6E-21 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VMUT_1551 983d075157b8a51621ec75a0f94d99e2 444 Gene3D G3DSA:2.40.30.10 236 329 8.8E-39 T 23-10-2018 VMUT_1551 983d075157b8a51621ec75a0f94d99e2 444 TIGRFAM TIGR00483 EF-1_alpha: translation elongation factor EF-1, subunit alpha 12 439 7.6E-193 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 VMUT_1551 983d075157b8a51621ec75a0f94d99e2 444 Pfam PF00009 Elongation factor Tu GTP binding domain 14 230 1.0E-52 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VMUT_1551 983d075157b8a51621ec75a0f94d99e2 444 SUPERFAMILY SSF50465 333 436 5.9E-34 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal VMUT_1551 983d075157b8a51621ec75a0f94d99e2 444 Gene3D G3DSA:2.40.30.10 330 436 3.2E-38 T 23-10-2018 VMUT_0908 4c592f1a03862ba1b925a01587633324 148 TIGRFAM TIGR00405 KOW_elon_Spt5: transcription elongation factor Spt5 6 146 1.6E-28 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 VMUT_0908 4c592f1a03862ba1b925a01587633324 148 Hamap MF_00950 Transcription elongation factor Spt5 [spt5]. 4 147 35.207 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 VMUT_0908 4c592f1a03862ba1b925a01587633324 148 SMART SM00739 91 118 0.0084 T 23-10-2018 IPR005824 KOW VMUT_0908 4c592f1a03862ba1b925a01587633324 148 SMART SM00738 2 89 4.7E-6 T 23-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 VMUT_0908 4c592f1a03862ba1b925a01587633324 148 Pfam PF03439 Early transcription elongation factor of RNA pol II, NGN section 6 84 1.1E-14 T 23-10-2018 IPR005100 NGN domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 VMUT_0908 4c592f1a03862ba1b925a01587633324 148 Gene3D G3DSA:3.30.70.940 5 92 3.5E-22 T 23-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 VMUT_0908 4c592f1a03862ba1b925a01587633324 148 Gene3D G3DSA:2.30.30.30 93 148 6.5E-18 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 VMUT_0908 4c592f1a03862ba1b925a01587633324 148 SUPERFAMILY SSF50104 60 145 9.03E-12 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily VMUT_1266 22ba19bceafd8a89e6fd2c4e012905e0 503 Gene3D G3DSA:1.20.120.640 335 496 9.1E-22 T 23-10-2018 VMUT_1266 22ba19bceafd8a89e6fd2c4e012905e0 503 SUPERFAMILY SSF47323 368 495 3.6E-25 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_1266 22ba19bceafd8a89e6fd2c4e012905e0 503 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 83 92 7.4E-26 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 VMUT_1266 22ba19bceafd8a89e6fd2c4e012905e0 503 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 249 270 7.4E-26 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 VMUT_1266 22ba19bceafd8a89e6fd2c4e012905e0 503 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 218 236 7.4E-26 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 VMUT_1266 22ba19bceafd8a89e6fd2c4e012905e0 503 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 47 58 7.4E-26 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 VMUT_1266 22ba19bceafd8a89e6fd2c4e012905e0 503 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 25 494 2.4E-139 T 23-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 VMUT_1266 22ba19bceafd8a89e6fd2c4e012905e0 503 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 43 341 9.3E-113 T 23-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 VMUT_1266 22ba19bceafd8a89e6fd2c4e012905e0 503 Pfam PF09190 DALR domain 382 441 4.8E-7 T 23-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 VMUT_1266 22ba19bceafd8a89e6fd2c4e012905e0 503 Gene3D G3DSA:3.40.50.620 9 333 3.2E-117 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_1266 22ba19bceafd8a89e6fd2c4e012905e0 503 SMART SM00840 381 444 3.2E-4 T 23-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 VMUT_1266 22ba19bceafd8a89e6fd2c4e012905e0 503 SUPERFAMILY SSF52374 26 342 2.56E-85 T 23-10-2018 VMUT_1266 22ba19bceafd8a89e6fd2c4e012905e0 503 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 24 496 33.208 T 23-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 VMUT_0269 db2d4d64215f3e35e292344050c1c218 303 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 50 302 27.316 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 VMUT_0269 db2d4d64215f3e35e292344050c1c218 303 SUPERFAMILY SSF55979 51 155 1.04E-26 T 23-10-2018 VMUT_0269 db2d4d64215f3e35e292344050c1c218 303 Gene3D G3DSA:3.70.10.10 50 297 3.6E-72 T 23-10-2018 VMUT_0269 db2d4d64215f3e35e292344050c1c218 303 SUPERFAMILY SSF55979 180 302 9.42E-23 T 23-10-2018 VMUT_0269 db2d4d64215f3e35e292344050c1c218 303 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 82 100 4.5E-9 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 VMUT_0269 db2d4d64215f3e35e292344050c1c218 303 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 104 128 4.5E-9 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 VMUT_0269 db2d4d64215f3e35e292344050c1c218 303 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 288 303 4.5E-9 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 VMUT_0269 db2d4d64215f3e35e292344050c1c218 303 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 180 300 4.6E-6 T 23-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 VMUT_0269 db2d4d64215f3e35e292344050c1c218 303 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 56 151 1.1E-13 T 23-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 VMUT_0543 f3dfdf5eda5acf83ee8922e3ccce78eb 470 SUPERFAMILY SSF55103 195 470 4.58E-41 T 23-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 VMUT_0543 f3dfdf5eda5acf83ee8922e3ccce78eb 470 Pfam PF02913 FAD linked oxidases, C-terminal domain 222 468 3.7E-42 T 23-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 VMUT_0543 f3dfdf5eda5acf83ee8922e3ccce78eb 470 Gene3D G3DSA:1.10.45.10 422 469 5.0E-9 T 23-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 VMUT_0543 f3dfdf5eda5acf83ee8922e3ccce78eb 470 Pfam PF01565 FAD binding domain 45 184 4.6E-36 T 23-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 VMUT_0543 f3dfdf5eda5acf83ee8922e3ccce78eb 470 SUPERFAMILY SSF56176 11 222 1.64E-58 T 23-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VMUT_0543 f3dfdf5eda5acf83ee8922e3ccce78eb 470 Gene3D G3DSA:3.30.70.2740 341 421 8.0E-16 T 23-10-2018 VMUT_0543 f3dfdf5eda5acf83ee8922e3ccce78eb 470 Gene3D G3DSA:3.30.465.40 7 239 4.4E-60 T 23-10-2018 VMUT_0678 12df0ee672e2cd9084c6e073aa44a80d 306 SUPERFAMILY SSF51556 1 291 1.19E-17 T 23-10-2018 IPR032466 Metal-dependent hydrolase VMUT_0678 12df0ee672e2cd9084c6e073aa44a80d 306 Gene3D G3DSA:3.20.20.140 2 296 1.3E-26 T 23-10-2018 VMUT_0678 12df0ee672e2cd9084c6e073aa44a80d 306 Pfam PF04909 Amidohydrolase 86 290 2.3E-13 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VMUT_1623 a9a07cf839bf121397eeb1f143a45067 422 Gene3D G3DSA:2.170.190.11 53 146 1.3E-82 T 23-10-2018 VMUT_1623 a9a07cf839bf121397eeb1f143a45067 422 SUPERFAMILY SSF53218 180 335 1.83E-27 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily VMUT_1623 a9a07cf839bf121397eeb1f143a45067 422 Gene3D G3DSA:3.40.980.10 180 342 1.3E-82 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily VMUT_1623 a9a07cf839bf121397eeb1f143a45067 422 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 258 271 - T 23-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 VMUT_1623 a9a07cf839bf121397eeb1f143a45067 422 Pfam PF00994 Probable molybdopterin binding domain 186 330 7.8E-23 T 23-10-2018 IPR001453 MoaB/Mog domain VMUT_1623 a9a07cf839bf121397eeb1f143a45067 422 Gene3D G3DSA:2.40.340.10 343 411 1.3E-82 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VMUT_1623 a9a07cf839bf121397eeb1f143a45067 422 Pfam PF03453 MoeA N-terminal region (domain I and II) 19 172 2.2E-31 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VMUT_1623 a9a07cf839bf121397eeb1f143a45067 422 SMART SM00852 185 332 1.0E-21 T 23-10-2018 IPR001453 MoaB/Mog domain VMUT_1623 a9a07cf839bf121397eeb1f143a45067 422 Gene3D G3DSA:3.90.105.10 29 179 1.3E-82 T 23-10-2018 VMUT_1623 a9a07cf839bf121397eeb1f143a45067 422 SUPERFAMILY SSF63882 19 181 7.59E-43 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VMUT_0389 85ad397946218da78c83d8347ea86c66 348 Gene3D G3DSA:3.40.50.720 4 336 3.9E-134 T 23-10-2018 VMUT_0389 85ad397946218da78c83d8347ea86c66 348 SMART SM00846 3 141 8.4E-6 T 23-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 VMUT_0389 85ad397946218da78c83d8347ea86c66 348 Hamap MF_00559 Glyceraldehyde-3-phosphate dehydrogenase [gap]. 1 348 167.056 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 VMUT_0389 85ad397946218da78c83d8347ea86c66 348 TIGRFAM TIGR01546 GAPDH-II_archae: glyceraldehyde-3-phosphate dehydrogenase, type II 5 336 1.8E-140 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 VMUT_0389 85ad397946218da78c83d8347ea86c66 348 Gene3D G3DSA:3.30.360.10 141 309 3.9E-134 T 23-10-2018 VMUT_0389 85ad397946218da78c83d8347ea86c66 348 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 139 146 - T 23-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 VMUT_0389 85ad397946218da78c83d8347ea86c66 348 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 300 1.7E-17 T 23-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 VMUT_0389 85ad397946218da78c83d8347ea86c66 348 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 96 6.0E-11 T 23-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VMUT_0389 85ad397946218da78c83d8347ea86c66 348 SUPERFAMILY SSF55347 141 304 1.31E-45 T 23-10-2018 VMUT_0389 85ad397946218da78c83d8347ea86c66 348 PIRSF PIRSF000149 1 324 1.5E-69 T 23-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 VMUT_0389 85ad397946218da78c83d8347ea86c66 348 SUPERFAMILY SSF51735 3 151 2.18E-34 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0978 c3fff8c6944c5445768e483ec57830d0 473 Gene3D G3DSA:3.40.120.10 3 151 9.5E-36 T 23-10-2018 VMUT_0978 c3fff8c6944c5445768e483ec57830d0 473 Gene3D G3DSA:3.40.120.10 264 348 6.7E-52 T 23-10-2018 VMUT_0978 c3fff8c6944c5445768e483ec57830d0 473 SUPERFAMILY SSF53738 251 384 1.69E-23 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VMUT_0978 c3fff8c6944c5445768e483ec57830d0 473 Gene3D G3DSA:3.30.310.50 390 472 1.5E-18 T 23-10-2018 VMUT_0978 c3fff8c6944c5445768e483ec57830d0 473 SUPERFAMILY SSF55957 372 472 9.16E-19 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VMUT_0978 c3fff8c6944c5445768e483ec57830d0 473 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 8 139 5.9E-33 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VMUT_0978 c3fff8c6944c5445768e483ec57830d0 473 SUPERFAMILY SSF53738 164 261 6.28E-20 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VMUT_0978 c3fff8c6944c5445768e483ec57830d0 473 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 163 260 1.3E-21 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VMUT_0978 c3fff8c6944c5445768e483ec57830d0 473 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 243 258 1.4E-8 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VMUT_0978 c3fff8c6944c5445768e483ec57830d0 473 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 98 112 1.4E-8 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VMUT_0978 c3fff8c6944c5445768e483ec57830d0 473 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 215 228 1.4E-8 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VMUT_0978 c3fff8c6944c5445768e483ec57830d0 473 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 418 463 1.1E-10 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VMUT_0978 c3fff8c6944c5445768e483ec57830d0 473 SUPERFAMILY SSF53738 7 188 2.2E-35 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VMUT_0978 c3fff8c6944c5445768e483ec57830d0 473 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 269 374 8.7E-22 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VMUT_0978 c3fff8c6944c5445768e483ec57830d0 473 Gene3D G3DSA:3.40.120.10 180 366 6.7E-52 T 23-10-2018 VMUT_1838 bcc8a210cec75aaa35275e1b44dcca41 551 Gene3D G3DSA:3.40.50.12780 1 436 2.4E-101 T 23-10-2018 VMUT_1838 bcc8a210cec75aaa35275e1b44dcca41 551 Pfam PF00501 AMP-binding enzyme 30 441 1.6E-81 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VMUT_1838 bcc8a210cec75aaa35275e1b44dcca41 551 Pfam PF13193 AMP-binding enzyme C-terminal domain 451 529 3.3E-17 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VMUT_1838 bcc8a210cec75aaa35275e1b44dcca41 551 SUPERFAMILY SSF56801 3 542 3.53E-125 T 23-10-2018 VMUT_1838 bcc8a210cec75aaa35275e1b44dcca41 551 Gene3D G3DSA:3.30.300.310 437 545 1.1E-30 T 23-10-2018 VMUT_1770 e3b1e6f82c0a2daaa30c9949bb160a06 250 SUPERFAMILY SSF52833 21 134 4.98E-11 T 23-10-2018 IPR036249 Thioredoxin-like superfamily VMUT_1770 e3b1e6f82c0a2daaa30c9949bb160a06 250 Gene3D G3DSA:3.40.30.10 144 243 1.4E-18 T 23-10-2018 VMUT_1770 e3b1e6f82c0a2daaa30c9949bb160a06 250 Pfam PF13192 Thioredoxin domain 162 241 4.3E-9 T 23-10-2018 IPR012336 Thioredoxin-like fold VMUT_1770 e3b1e6f82c0a2daaa30c9949bb160a06 250 SUPERFAMILY SSF52833 142 247 1.7E-15 T 23-10-2018 IPR036249 Thioredoxin-like superfamily VMUT_1770 e3b1e6f82c0a2daaa30c9949bb160a06 250 TIGRFAM TIGR02187 GlrX_arch: glutaredoxin-like domain protein 21 242 6.3E-53 T 23-10-2018 IPR011903 Glutaredoxin-like domain VMUT_1770 e3b1e6f82c0a2daaa30c9949bb160a06 250 Gene3D G3DSA:3.40.30.10 14 133 1.6E-26 T 23-10-2018 VMUT_0471 fa109cffbba7815aaa98c0232ec122b5 77 Hamap MF_00803 Ribosome biogenesis protein Nop10 [nop10]. 3 54 18.764 T 23-10-2018 IPR023532 H/ACA ribonucleoprotein complex subunit Nop10 , archaeal-type GO:0001522|GO:0030515|GO:0042254 VMUT_0471 fa109cffbba7815aaa98c0232ec122b5 77 SUPERFAMILY SSF144210 5 51 1.44E-17 T 23-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 VMUT_0471 fa109cffbba7815aaa98c0232ec122b5 77 Pfam PF04135 Nucleolar RNA-binding protein, Nop10p family 1 50 9.2E-22 T 23-10-2018 IPR007264 H/ACA ribonucleoprotein complex, subunit Nop10 GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 VMUT_0471 fa109cffbba7815aaa98c0232ec122b5 77 Gene3D G3DSA:2.20.28.40 1 58 7.8E-23 T 23-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 VMUT_0447 486a8d452c085227c08854ec0e7ed93e 316 SMART SM00981 59 149 2.0E-13 T 23-10-2018 IPR004114 THUMP domain GO:0003723 VMUT_0447 486a8d452c085227c08854ec0e7ed93e 316 Gene3D G3DSA:3.30.2130.30 17 151 7.7E-15 T 23-10-2018 VMUT_0447 486a8d452c085227c08854ec0e7ed93e 316 SUPERFAMILY SSF143437 45 147 7.32E-19 T 23-10-2018 VMUT_0447 486a8d452c085227c08854ec0e7ed93e 316 Pfam PF02926 THUMP domain 30 145 1.1E-14 T 23-10-2018 IPR004114 THUMP domain GO:0003723 VMUT_1341 6e56c95747f34fce88c0bd4c124b2268 415 Pfam PF02687 FtsX-like permease family 294 408 5.4E-12 T 23-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 VMUT_1341 6e56c95747f34fce88c0bd4c124b2268 415 Pfam PF12704 MacB-like periplasmic core domain 21 238 1.3E-8 T 23-10-2018 IPR025857 MacB-like periplasmic core domain VMUT_0747 459c90275610110fabdba5c8bfb4e701 460 SUPERFAMILY SSF53639 271 451 6.28E-65 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VMUT_0747 459c90275610110fabdba5c8bfb4e701 460 Gene3D G3DSA:3.40.225.10 274 458 1.3E-72 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VMUT_0747 459c90275610110fabdba5c8bfb4e701 460 Pfam PF10120 Thiamine-phosphate synthase 278 449 1.6E-65 T 23-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 VMUT_0747 459c90275610110fabdba5c8bfb4e701 460 Pfam PF08543 Phosphomethylpyrimidine kinase 15 261 2.6E-93 T 23-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 VMUT_0747 459c90275610110fabdba5c8bfb4e701 460 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 8 262 8.5E-99 T 23-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 VMUT_0747 459c90275610110fabdba5c8bfb4e701 460 Gene3D G3DSA:3.40.1190.20 1 273 2.0E-98 T 23-10-2018 IPR029056 Ribokinase-like VMUT_0747 459c90275610110fabdba5c8bfb4e701 460 SUPERFAMILY SSF53613 3 266 4.21E-80 T 23-10-2018 IPR029056 Ribokinase-like VMUT_1276 c82b754a45e603fa1beaa4681f64395e 130 Gene3D G3DSA:3.30.160.60 63 130 6.6E-8 T 23-10-2018 VMUT_1276 c82b754a45e603fa1beaa4681f64395e 130 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 106 127 - T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 VMUT_1276 c82b754a45e603fa1beaa4681f64395e 130 SMART SM00355 40 61 1.2 T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 VMUT_1276 c82b754a45e603fa1beaa4681f64395e 130 SMART SM00355 104 127 0.79 T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 VMUT_1276 c82b754a45e603fa1beaa4681f64395e 130 SMART SM00355 69 91 0.13 T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 VMUT_1276 c82b754a45e603fa1beaa4681f64395e 130 SUPERFAMILY SSF57667 67 123 3.24E-5 T 23-10-2018 IPR036236 Zinc finger C2H2 superfamily VMUT_1276 c82b754a45e603fa1beaa4681f64395e 130 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 71 91 - T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 VMUT_1276 c82b754a45e603fa1beaa4681f64395e 130 Pfam PF05605 Drought induced 19 protein (Di19), zinc-binding 40 89 1.3E-6 T 23-10-2018 IPR008598 Drought induced 19 protein type, zinc-binding domain VMUT_2132 89cfbcb5f91f13f0abf7fb8bf1a8b635 124 Pfam PF01934 Protein of unknown function DUF86 11 101 6.8E-8 T 23-10-2018 IPR008201 Protein of unknown function DUF86 VMUT_1617 bd82fbc9f102124b4a05e351d89ffbcb 48 Pfam PF03911 Sec61beta family 6 45 1.5E-12 T 23-10-2018 IPR016482 Protein transport protein SecG/Sec61-beta/Sbh Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 VMUT_1294 45336937983d19ec38f8dbbe16bd1bd3 561 SUPERFAMILY SSF52016 380 557 1.88E-62 T 23-10-2018 VMUT_1294 45336937983d19ec38f8dbbe16bd1bd3 561 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 6 558 46.06 T 23-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VMUT_1294 45336937983d19ec38f8dbbe16bd1bd3 561 Pfam PF00920 Dehydratase family 36 555 3.8E-209 T 23-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VMUT_1294 45336937983d19ec38f8dbbe16bd1bd3 561 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 124 134 - T 23-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VMUT_1294 45336937983d19ec38f8dbbe16bd1bd3 561 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 19 557 5.6E-217 T 23-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VMUT_1294 45336937983d19ec38f8dbbe16bd1bd3 561 Gene3D G3DSA:3.50.30.80 380 529 5.8E-56 T 23-10-2018 VMUT_1294 45336937983d19ec38f8dbbe16bd1bd3 561 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 466 477 - T 23-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VMUT_1294 45336937983d19ec38f8dbbe16bd1bd3 561 SUPERFAMILY SSF143975 3 379 4.58E-132 T 23-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VMUT_0525 66bdedcef416ef7546eeff904e4e7ce1 138 Gene3D G3DSA:3.40.1260.10 1 138 7.3E-34 T 23-10-2018 IPR027396 DsrEFH-like VMUT_0525 66bdedcef416ef7546eeff904e4e7ce1 138 Pfam PF02635 DsrE/DsrF-like family 26 133 5.7E-9 T 23-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein VMUT_0525 66bdedcef416ef7546eeff904e4e7ce1 138 SUPERFAMILY SSF75169 6 133 1.01E-15 T 23-10-2018 IPR027396 DsrEFH-like VMUT_1473 f00c7b251dbb90722302304a33255522 255 Gene3D G3DSA:3.40.50.10770 46 202 4.6E-17 T 23-10-2018 VMUT_1473 f00c7b251dbb90722302304a33255522 255 Pfam PF09651 CRISPR-associated protein (Cas_APE2256) 67 197 2.4E-16 T 23-10-2018 IPR013442 CRISPR-associated protein APE2256 VMUT_0702 798c81f4bf8da7672c8e77ece95f92fa 378 Pfam PF01435 Peptidase family M48 205 375 3.2E-24 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 VMUT_0702 798c81f4bf8da7672c8e77ece95f92fa 378 Gene3D G3DSA:3.30.2010.10 189 277 9.1E-11 T 23-10-2018 VMUT_1663 eb0829acf420a6fe5a54a0a155409a94 389 SUPERFAMILY SSF51905 12 382 2.59E-53 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_1663 eb0829acf420a6fe5a54a0a155409a94 389 Gene3D G3DSA:3.30.9.10 92 321 3.6E-94 T 23-10-2018 VMUT_1663 eb0829acf420a6fe5a54a0a155409a94 389 Gene3D G3DSA:3.50.50.60 13 364 3.6E-94 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_1663 eb0829acf420a6fe5a54a0a155409a94 389 Pfam PF01266 FAD dependent oxidoreductase 13 358 8.7E-59 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VMUT_0761 6d846170828ee2a1e7387bcccf81face 667 Pfam PF00501 AMP-binding enzyme 115 539 1.0E-48 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VMUT_0761 6d846170828ee2a1e7387bcccf81face 667 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 50 105 1.6E-11 T 23-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 VMUT_0761 6d846170828ee2a1e7387bcccf81face 667 Gene3D G3DSA:3.30.300.30 535 643 4.9E-11 T 23-10-2018 VMUT_0761 6d846170828ee2a1e7387bcccf81face 667 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 3 651 1.8E-209 T 23-10-2018 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 VMUT_0761 6d846170828ee2a1e7387bcccf81face 667 ProSitePatterns PS00455 Putative AMP-binding domain signature. 281 292 - T 23-10-2018 IPR020845 AMP-binding, conserved site VMUT_0761 6d846170828ee2a1e7387bcccf81face 667 SUPERFAMILY SSF56801 43 649 1.44E-116 T 23-10-2018 VMUT_0761 6d846170828ee2a1e7387bcccf81face 667 Gene3D G3DSA:3.40.50.12780 84 532 2.6E-57 T 23-10-2018 VMUT_1689 c1a1c0e4535f09032e6fd07aa506378b 80 Gene3D G3DSA:2.20.28.30 34 79 1.4E-16 T 23-10-2018 VMUT_1689 c1a1c0e4535f09032e6fd07aa506378b 80 SMART SM00659 34 79 6.8E-8 T 23-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 VMUT_1689 c1a1c0e4535f09032e6fd07aa506378b 80 SUPERFAMILY SSF63393 35 76 1.7E-9 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 VMUT_1481 b643b1499e1b2c81df822215cb5b8911 327 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 26 288 2.7E-15 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VMUT_1481 b643b1499e1b2c81df822215cb5b8911 327 SUPERFAMILY SSF52540 6 318 3.89E-23 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1481 b643b1499e1b2c81df822215cb5b8911 327 Gene3D G3DSA:3.40.50.300 4 319 3.3E-22 T 23-10-2018 VMUT_1481 b643b1499e1b2c81df822215cb5b8911 327 SMART SM00382 23 304 1.3E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_1736 66e6b6ead393b31f5d3332e26fd09414 318 PIRSF PIRSF005856 1 318 8.6E-99 T 23-10-2018 IPR016467 DNA recombination and repair protein, RecA-like Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 VMUT_1736 66e6b6ead393b31f5d3332e26fd09414 318 Pfam PF14520 Helix-hairpin-helix domain 7 61 1.9E-9 T 23-10-2018 VMUT_1736 66e6b6ead393b31f5d3332e26fd09414 318 SUPERFAMILY SSF47794 5 64 8.63E-12 T 23-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 VMUT_1736 66e6b6ead393b31f5d3332e26fd09414 318 Gene3D G3DSA:3.40.50.300 69 318 1.2E-69 T 23-10-2018 VMUT_1736 66e6b6ead393b31f5d3332e26fd09414 318 Gene3D G3DSA:1.10.150.20 6 66 9.6E-15 T 23-10-2018 VMUT_1736 66e6b6ead393b31f5d3332e26fd09414 318 SMART SM00278 39 58 140.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 VMUT_1736 66e6b6ead393b31f5d3332e26fd09414 318 SMART SM00278 6 25 0.25 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 VMUT_1736 66e6b6ead393b31f5d3332e26fd09414 318 Pfam PF08423 Rad51 71 317 4.4E-72 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 VMUT_1736 66e6b6ead393b31f5d3332e26fd09414 318 SUPERFAMILY SSF52540 82 317 3.97E-52 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1736 66e6b6ead393b31f5d3332e26fd09414 318 SMART SM00382 102 286 3.9E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_1323 c0c896c87f7bc8f11a81579a967f6c12 238 PRINTS PR00052 Fibrillarin signature 163 192 6.9E-62 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 VMUT_1323 c0c896c87f7bc8f11a81579a967f6c12 238 PRINTS PR00052 Fibrillarin signature 81 102 6.9E-62 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 VMUT_1323 c0c896c87f7bc8f11a81579a967f6c12 238 PRINTS PR00052 Fibrillarin signature 54 73 6.9E-62 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 VMUT_1323 c0c896c87f7bc8f11a81579a967f6c12 238 PRINTS PR00052 Fibrillarin signature 215 236 6.9E-62 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 VMUT_1323 c0c896c87f7bc8f11a81579a967f6c12 238 PRINTS PR00052 Fibrillarin signature 31 50 6.9E-62 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 VMUT_1323 c0c896c87f7bc8f11a81579a967f6c12 238 PRINTS PR00052 Fibrillarin signature 133 162 6.9E-62 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 VMUT_1323 c0c896c87f7bc8f11a81579a967f6c12 238 Gene3D G3DSA:3.40.50.150 59 237 1.1E-66 T 23-10-2018 VMUT_1323 c0c896c87f7bc8f11a81579a967f6c12 238 ProSitePatterns PS00566 Fibrillarin signature. 106 120 - T 23-10-2018 IPR020813 Fibrillarin, conserved site GO:0003723|GO:0006364|GO:0008168 VMUT_1323 c0c896c87f7bc8f11a81579a967f6c12 238 Hamap MF_00351 Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase [flpA]. 24 237 43.063 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 VMUT_1323 c0c896c87f7bc8f11a81579a967f6c12 238 PIRSF PIRSF006540 1 238 4.1E-97 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 VMUT_1323 c0c896c87f7bc8f11a81579a967f6c12 238 SUPERFAMILY SSF53335 12 235 1.08E-50 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_1323 c0c896c87f7bc8f11a81579a967f6c12 238 SMART SM01206 10 238 6.5E-142 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 VMUT_1323 c0c896c87f7bc8f11a81579a967f6c12 238 Gene3D G3DSA:3.30.200.20 4 58 7.8E-22 T 23-10-2018 VMUT_1323 c0c896c87f7bc8f11a81579a967f6c12 238 Pfam PF01269 Fibrillarin 10 236 1.2E-101 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 VMUT_0873 af24e291080cad1b3a4c211e6389be07 61 Gene3D G3DSA:1.10.10.10 3 60 2.8E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_0873 af24e291080cad1b3a4c211e6389be07 61 SUPERFAMILY SSF46785 2 57 8.65E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_2234 6a42824dbb2648e23560d19d41822554 233 SUPERFAMILY SSF117396 2 229 3.01E-66 T 23-10-2018 IPR036520 UPF0759 superfamily VMUT_2234 6a42824dbb2648e23560d19d41822554 233 Gene3D G3DSA:3.20.20.410 1 231 9.5E-53 T 23-10-2018 IPR036520 UPF0759 superfamily VMUT_2234 6a42824dbb2648e23560d19d41822554 233 Pfam PF01904 Protein of unknown function DUF72 19 224 2.0E-44 T 23-10-2018 IPR002763 Protein of unknown function DUF72 VMUT_1959 f732dcf0efc24eee6b1136553c9c3db0 194 Gene3D G3DSA:3.30.70.3270 40 176 1.5E-21 T 23-10-2018 VMUT_1959 f732dcf0efc24eee6b1136553c9c3db0 194 SUPERFAMILY SSF54862 40 133 1.63E-20 T 23-10-2018 VMUT_1959 f732dcf0efc24eee6b1136553c9c3db0 194 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 96 107 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_1959 f732dcf0efc24eee6b1136553c9c3db0 194 Pfam PF12838 4Fe-4S dicluster domain 61 110 3.2E-10 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_1959 f732dcf0efc24eee6b1136553c9c3db0 194 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 62 73 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_0519 771313ecc1c2643e62240b274956d120 326 Gene3D G3DSA:3.30.428.10 36 155 1.0E-85 T 23-10-2018 IPR036265 HIT-like superfamily VMUT_0519 771313ecc1c2643e62240b274956d120 326 SUPERFAMILY SSF54197 159 316 6.19E-38 T 23-10-2018 IPR036265 HIT-like superfamily VMUT_0519 771313ecc1c2643e62240b274956d120 326 PIRSF PIRSF000808 1 318 3.8E-96 T 23-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 VMUT_0519 771313ecc1c2643e62240b274956d120 326 SUPERFAMILY SSF54197 6 156 4.89E-38 T 23-10-2018 IPR036265 HIT-like superfamily VMUT_0519 771313ecc1c2643e62240b274956d120 326 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 10 316 2.4E-43 T 23-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 VMUT_0519 771313ecc1c2643e62240b274956d120 326 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 163 319 1.3E-18 T 23-10-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 VMUT_0519 771313ecc1c2643e62240b274956d120 326 Gene3D G3DSA:3.30.428.10 8 315 1.0E-85 T 23-10-2018 IPR036265 HIT-like superfamily VMUT_0519 771313ecc1c2643e62240b274956d120 326 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 8 156 9.5E-16 T 23-10-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 VMUT_0068 1e066e5f731f0fa57cd990fdc958eb8b 287 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 118 249 2.7E-31 T 23-10-2018 IPR006342 Methyltransferase FkbM VMUT_0068 1e066e5f731f0fa57cd990fdc958eb8b 287 Gene3D G3DSA:3.40.50.150 106 274 5.5E-33 T 23-10-2018 VMUT_0068 1e066e5f731f0fa57cd990fdc958eb8b 287 Pfam PF05050 Methyltransferase FkbM domain 121 251 3.9E-16 T 23-10-2018 IPR006342 Methyltransferase FkbM VMUT_0068 1e066e5f731f0fa57cd990fdc958eb8b 287 SUPERFAMILY SSF53335 32 269 5.53E-41 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_2249 b87e3e93a274896dcc7bc3d105a26a62 349 Pfam PF07690 Major Facilitator Superfamily 9 317 1.0E-26 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_2249 b87e3e93a274896dcc7bc3d105a26a62 349 SUPERFAMILY SSF103473 4 347 1.7E-36 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_2249 b87e3e93a274896dcc7bc3d105a26a62 349 Gene3D G3DSA:1.20.1250.20 164 349 1.3E-9 T 23-10-2018 VMUT_2249 b87e3e93a274896dcc7bc3d105a26a62 349 Gene3D G3DSA:1.20.1250.20 1 163 6.9E-20 T 23-10-2018 VMUT_1907 e0fbc484054dde595cfaf45176956d9b 100 SUPERFAMILY SSF46785 4 97 3.56E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_1907 e0fbc484054dde595cfaf45176956d9b 100 Pfam PF12840 Helix-turn-helix domain 10 63 7.9E-11 T 23-10-2018 VMUT_1907 e0fbc484054dde595cfaf45176956d9b 100 SMART SM00418 9 94 1.2E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VMUT_1907 e0fbc484054dde595cfaf45176956d9b 100 Gene3D G3DSA:1.10.10.10 3 82 2.9E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_1207 220a90b585e474dcc11e449a57f2927b 768 SMART SM00487 27 214 7.0E-31 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain VMUT_1207 220a90b585e474dcc11e449a57f2927b 768 Gene3D G3DSA:1.10.150.20 675 730 6.6E-16 T 23-10-2018 VMUT_1207 220a90b585e474dcc11e449a57f2927b 768 SUPERFAMILY SSF52540 42 406 1.21E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1207 220a90b585e474dcc11e449a57f2927b 768 Pfam PF14520 Helix-hairpin-helix domain 678 732 4.6E-13 T 23-10-2018 VMUT_1207 220a90b585e474dcc11e449a57f2927b 768 Pfam PF00271 Helicase conserved C-terminal domain 301 393 1.8E-7 T 23-10-2018 IPR001650 Helicase, C-terminal VMUT_1207 220a90b585e474dcc11e449a57f2927b 768 Pfam PF00270 DEAD/DEAH box helicase 33 190 1.1E-26 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 VMUT_1207 220a90b585e474dcc11e449a57f2927b 768 SUPERFAMILY SSF158702 518 733 7.06E-50 T 23-10-2018 VMUT_1207 220a90b585e474dcc11e449a57f2927b 768 SMART SM00490 302 393 2.2E-17 T 23-10-2018 IPR001650 Helicase, C-terminal VMUT_1207 220a90b585e474dcc11e449a57f2927b 768 Gene3D G3DSA:1.10.3380.30 431 673 1.9E-65 T 23-10-2018 VMUT_1207 220a90b585e474dcc11e449a57f2927b 768 Gene3D G3DSA:3.40.50.300 211 419 9.8E-56 T 23-10-2018 VMUT_1207 220a90b585e474dcc11e449a57f2927b 768 SUPERFAMILY SSF46785 424 517 1.5E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_1207 220a90b585e474dcc11e449a57f2927b 768 Gene3D G3DSA:3.40.50.300 19 210 2.4E-64 T 23-10-2018 VMUT_1207 220a90b585e474dcc11e449a57f2927b 768 Hamap MF_00442 ATP-dependent DNA helicase Hel308 [hel308]. 15 733 31.292 T 23-10-2018 IPR022965 ATP-dependent DNA helicase Hel308 GO:0004386 VMUT_1355 4edc37862cef29377c08a7f3243ca033 267 SUPERFAMILY SSF53850 6 259 4.75E-81 T 23-10-2018 VMUT_1355 4edc37862cef29377c08a7f3243ca033 267 Gene3D G3DSA:3.40.190.10 6 255 1.1E-89 T 23-10-2018 VMUT_1355 4edc37862cef29377c08a7f3243ca033 267 Pfam PF02621 Menaquinone biosynthesis 6 255 2.5E-77 T 23-10-2018 IPR003773 Menaquinone biosynthesis enzyme VMUT_1355 4edc37862cef29377c08a7f3243ca033 267 Hamap MF_00996 1,4-dihydroxy-6-naphtoate synthase [mqnD]. 3 260 39.522 T 23-10-2018 IPR030869 1,4-dihydroxy-6-naphtoate synthase GO:0009234|GO:0016829 VMUT_1355 4edc37862cef29377c08a7f3243ca033 267 Gene3D G3DSA:3.40.190.10 80 168 1.1E-89 T 23-10-2018 VMUT_0752 43e2fb2d9cdda11f7eff7c9615b46fbe 447 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 54 65 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_0752 43e2fb2d9cdda11f7eff7c9615b46fbe 447 Pfam PF13183 4Fe-4S dicluster domain 54 121 4.6E-12 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_0752 43e2fb2d9cdda11f7eff7c9615b46fbe 447 Gene3D G3DSA:1.10.1060.10 33 137 1.3E-7 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VMUT_0752 43e2fb2d9cdda11f7eff7c9615b46fbe 447 Pfam PF02754 Cysteine-rich domain 321 408 4.4E-8 T 23-10-2018 IPR004017 Cysteine-rich domain VMUT_0752 43e2fb2d9cdda11f7eff7c9615b46fbe 447 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 107 118 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_0752 43e2fb2d9cdda11f7eff7c9615b46fbe 447 SUPERFAMILY SSF46548 44 136 6.8E-20 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VMUT_0278 9a799ed0adcada155b3389d29506fd57 113 Pfam PF03551 Transcriptional regulator PadR-like family 22 79 1.5E-9 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal VMUT_0278 9a799ed0adcada155b3389d29506fd57 113 SUPERFAMILY SSF46785 5 101 3.83E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0278 9a799ed0adcada155b3389d29506fd57 113 Gene3D G3DSA:1.10.10.10 1 105 4.0E-15 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_1400 e98e4bd62f0af7af3a04d4f309020d76 331 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 3 317 24.533 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 VMUT_1400 e98e4bd62f0af7af3a04d4f309020d76 331 Gene3D G3DSA:3.100.10.20 2 82 5.5E-15 T 23-10-2018 VMUT_1400 e98e4bd62f0af7af3a04d4f309020d76 331 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 5 315 3.0E-71 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 VMUT_1400 e98e4bd62f0af7af3a04d4f309020d76 331 Pfam PF01867 CRISPR associated protein Cas1 5 263 2.2E-62 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 VMUT_1400 e98e4bd62f0af7af3a04d4f309020d76 331 Gene3D G3DSA:1.20.120.920 84 330 2.8E-54 T 23-10-2018 VMUT_1314 7f319998894cceb0be20c15ac39ecc5b 207 PIRSF PIRSF000709 2 180 1.3E-10 T 23-10-2018 VMUT_1314 7f319998894cceb0be20c15ac39ecc5b 207 SMART SM00855 2 148 2.6E-15 T 23-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 VMUT_1314 7f319998894cceb0be20c15ac39ecc5b 207 Gene3D G3DSA:3.40.50.1240 2 187 7.4E-42 T 23-10-2018 IPR029033 Histidine phosphatase superfamily VMUT_1314 7f319998894cceb0be20c15ac39ecc5b 207 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 5 14 - T 23-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 VMUT_1314 7f319998894cceb0be20c15ac39ecc5b 207 SUPERFAMILY SSF53254 3 183 1.47E-42 T 23-10-2018 IPR029033 Histidine phosphatase superfamily VMUT_1314 7f319998894cceb0be20c15ac39ecc5b 207 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 181 2.7E-37 T 23-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 VMUT_1047 e8dd0058212c059d57f11f4e7cabe099 357 SUPERFAMILY SSF53756 2 350 2.12E-56 T 23-10-2018 VMUT_1047 e8dd0058212c059d57f11f4e7cabe099 357 Pfam PF13439 Glycosyltransferase Family 4 14 182 2.5E-21 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 VMUT_1047 e8dd0058212c059d57f11f4e7cabe099 357 Gene3D G3DSA:3.40.50.2000 198 352 1.9E-22 T 23-10-2018 VMUT_1047 e8dd0058212c059d57f11f4e7cabe099 357 Gene3D G3DSA:3.40.50.2000 1 197 5.0E-32 T 23-10-2018 VMUT_1047 e8dd0058212c059d57f11f4e7cabe099 357 Pfam PF00534 Glycosyl transferases group 1 189 299 1.6E-16 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 VMUT_1933 b5920536aff676f0683a73a84dc4ebbe 374 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 4 345 37.809 T 23-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 VMUT_1933 b5920536aff676f0683a73a84dc4ebbe 374 Pfam PF02222 ATP-grasp domain 104 268 2.7E-49 T 23-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type VMUT_1933 b5920536aff676f0683a73a84dc4ebbe 374 SUPERFAMILY SSF52440 4 79 8.92E-17 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily VMUT_1933 b5920536aff676f0683a73a84dc4ebbe 374 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 5 32 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 VMUT_1933 b5920536aff676f0683a73a84dc4ebbe 374 SUPERFAMILY SSF51246 294 363 2.75E-15 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 VMUT_1933 b5920536aff676f0683a73a84dc4ebbe 374 SUPERFAMILY SSF56059 95 289 1.24E-55 T 23-10-2018 VMUT_1933 b5920536aff676f0683a73a84dc4ebbe 374 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 5 350 6.3E-113 T 23-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 VMUT_1933 b5920536aff676f0683a73a84dc4ebbe 374 Gene3D G3DSA:3.30.470.20 170 366 1.0E-68 T 23-10-2018 VMUT_1933 b5920536aff676f0683a73a84dc4ebbe 374 Gene3D G3DSA:3.40.50.20 1 99 3.6E-25 T 23-10-2018 VMUT_1933 b5920536aff676f0683a73a84dc4ebbe 374 Gene3D G3DSA:3.30.1490.20 100 169 4.6E-15 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VMUT_0275 6bbb8139c2d600ffe65431b4ed86e1af 871 SMART SM00486 217 662 1.5E-87 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VMUT_0275 6bbb8139c2d600ffe65431b4ed86e1af 871 Gene3D G3DSA:3.30.420.10 220 421 3.1E-170 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VMUT_0275 6bbb8139c2d600ffe65431b4ed86e1af 871 Gene3D G3DSA:1.10.287.690 558 617 7.7E-58 T 23-10-2018 VMUT_0275 6bbb8139c2d600ffe65431b4ed86e1af 871 SUPERFAMILY SSF56672 452 859 1.89E-106 T 23-10-2018 VMUT_0275 6bbb8139c2d600ffe65431b4ed86e1af 871 SUPERFAMILY SSF53098 42 447 1.05E-59 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily VMUT_0275 6bbb8139c2d600ffe65431b4ed86e1af 871 Gene3D G3DSA:3.30.342.10 43 476 3.1E-170 T 23-10-2018 VMUT_0275 6bbb8139c2d600ffe65431b4ed86e1af 871 Gene3D G3DSA:3.90.1600.10 499 691 7.7E-58 T 23-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VMUT_0275 6bbb8139c2d600ffe65431b4ed86e1af 871 Pfam PF00136 DNA polymerase family B 452 828 2.2E-47 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VMUT_0275 6bbb8139c2d600ffe65431b4ed86e1af 871 Pfam PF03104 DNA polymerase family B, exonuclease domain 70 358 8.2E-30 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VMUT_0275 6bbb8139c2d600ffe65431b4ed86e1af 871 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 648 656 1.4E-9 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VMUT_0275 6bbb8139c2d600ffe65431b4ed86e1af 871 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 510 523 1.4E-9 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VMUT_0275 6bbb8139c2d600ffe65431b4ed86e1af 871 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 596 608 1.4E-9 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VMUT_0275 6bbb8139c2d600ffe65431b4ed86e1af 871 ProSitePatterns PS00116 DNA polymerase family B signature. 650 658 - T 23-10-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VMUT_0275 6bbb8139c2d600ffe65431b4ed86e1af 871 Gene3D G3DSA:1.10.132.60 712 868 1.7E-20 T 23-10-2018 VMUT_2281 bd06d9b4215d5aa0b2ee2a9790ed8b6c 333 SUPERFAMILY SSF55961 119 309 1.02E-23 T 23-10-2018 VMUT_2281 bd06d9b4215d5aa0b2ee2a9790ed8b6c 333 Pfam PF00355 Rieske [2Fe-2S] domain 2 83 1.7E-18 T 23-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 VMUT_2281 bd06d9b4215d5aa0b2ee2a9790ed8b6c 333 SUPERFAMILY SSF50022 2 111 1.96E-28 T 23-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VMUT_2281 bd06d9b4215d5aa0b2ee2a9790ed8b6c 333 Gene3D G3DSA:2.102.10.10 1 132 5.6E-33 T 23-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VMUT_1209 5c29e8be3d22bf09b53a79df55f9dbb8 334 Gene3D G3DSA:3.40.50.2000 160 331 1.0E-26 T 23-10-2018 VMUT_1209 5c29e8be3d22bf09b53a79df55f9dbb8 334 Pfam PF13692 Glycosyl transferases group 1 172 294 1.3E-14 T 23-10-2018 VMUT_1209 5c29e8be3d22bf09b53a79df55f9dbb8 334 SUPERFAMILY SSF53756 85 330 1.61E-41 T 23-10-2018 VMUT_0494 0b7a6ee7d2048355f2112612d4acc6d1 165 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 13 24 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_0494 0b7a6ee7d2048355f2112612d4acc6d1 165 TIGRFAM TIGR02060 aprB: adenylylsulfate reductase, beta subunit 4 127 1.6E-47 T 23-10-2018 IPR011802 Adenylylsulphate reductase, beta subunit VMUT_0494 0b7a6ee7d2048355f2112612d4acc6d1 165 Pfam PF12838 4Fe-4S dicluster domain 12 62 8.1E-12 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_0494 0b7a6ee7d2048355f2112612d4acc6d1 165 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 48 59 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_0494 0b7a6ee7d2048355f2112612d4acc6d1 165 Gene3D G3DSA:3.30.720.40 69 155 2.5E-32 T 23-10-2018 IPR038465 APS reductase, beta subunit, C-terminal domain superfamily VMUT_0494 0b7a6ee7d2048355f2112612d4acc6d1 165 Pfam PF12139 Adenosine-5'-phosphosulfate reductase beta subunit 65 142 5.3E-24 T 23-10-2018 IPR022738 Adenylylsulphate reductase, beta subunit, C-terminal VMUT_0494 0b7a6ee7d2048355f2112612d4acc6d1 165 SUPERFAMILY SSF54862 7 111 4.68E-19 T 23-10-2018 VMUT_0494 0b7a6ee7d2048355f2112612d4acc6d1 165 Gene3D G3DSA:3.30.70.20 5 68 2.3E-22 T 23-10-2018 VMUT_1510 ba3eea201990bd314669776e53cff5a1 552 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 26 533 8.6E-73 T 23-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 VMUT_2254 94912eded3c13048b37584b5f1ca26db 583 Pfam PF00501 AMP-binding enzyme 55 479 1.1E-106 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VMUT_2254 94912eded3c13048b37584b5f1ca26db 583 Pfam PF13193 AMP-binding enzyme C-terminal domain 489 565 3.0E-19 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VMUT_2254 94912eded3c13048b37584b5f1ca26db 583 SUPERFAMILY SSF56801 20 575 9.55E-154 T 23-10-2018 VMUT_2254 94912eded3c13048b37584b5f1ca26db 583 Gene3D G3DSA:3.40.50.12780 45 472 4.4E-116 T 23-10-2018 VMUT_2254 94912eded3c13048b37584b5f1ca26db 583 Gene3D G3DSA:3.30.300.310 475 581 3.7E-28 T 23-10-2018 VMUT_2254 94912eded3c13048b37584b5f1ca26db 583 ProSitePatterns PS00455 Putative AMP-binding domain signature. 229 240 - T 23-10-2018 IPR020845 AMP-binding, conserved site VMUT_0151 2dcceb82f7448b3b23c00b4ae9dd6822 316 SUPERFAMILY SSF52518 17 268 1.4E-71 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold VMUT_0151 2dcceb82f7448b3b23c00b4ae9dd6822 316 Gene3D G3DSA:3.40.50.970 29 205 8.6E-25 T 23-10-2018 VMUT_0151 2dcceb82f7448b3b23c00b4ae9dd6822 316 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 204 276 5.8E-19 T 23-10-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal VMUT_0151 2dcceb82f7448b3b23c00b4ae9dd6822 316 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 53 200 4.3E-28 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 VMUT_0151 2dcceb82f7448b3b23c00b4ae9dd6822 316 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 18 307 4.7E-128 T 23-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate VMUT_2214 921e5b1c5c177d3ab472db14531dcd8d 151 Gene3D G3DSA:3.30.1050.10 5 145 1.2E-20 T 23-10-2018 IPR036527 SCP2 sterol-binding domain superfamily VMUT_2214 921e5b1c5c177d3ab472db14531dcd8d 151 SUPERFAMILY SSF55718 3 149 9.12E-12 T 23-10-2018 IPR036527 SCP2 sterol-binding domain superfamily VMUT_0018 b1a55c98ee235ac1658ecef6cf832323 78 SMART SM00966 3 50 2.5E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VMUT_0018 b1a55c98ee235ac1658ecef6cf832323 78 SUPERFAMILY SSF89447 3 61 1.24E-12 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily VMUT_0018 b1a55c98ee235ac1658ecef6cf832323 78 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 3 48 1.9E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VMUT_0018 b1a55c98ee235ac1658ecef6cf832323 78 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 2 46 2.0E-16 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VMUT_0018 b1a55c98ee235ac1658ecef6cf832323 78 Gene3D G3DSA:2.10.260.10 2 43 3.0E-16 T 23-10-2018 VMUT_1708 c61d237e467eb642e5328557380456ff 260 Pfam PF01934 Protein of unknown function DUF86 22 126 2.2E-13 T 23-10-2018 IPR008201 Protein of unknown function DUF86 VMUT_1708 c61d237e467eb642e5328557380456ff 260 Gene3D G3DSA:1.20.120.580 2 132 4.6E-11 T 23-10-2018 IPR037038 Bsu32300-like superfamily VMUT_1708 c61d237e467eb642e5328557380456ff 260 SUPERFAMILY SSF81301 149 236 1.43E-9 T 23-10-2018 VMUT_1708 c61d237e467eb642e5328557380456ff 260 Gene3D G3DSA:3.30.460.10 138 229 3.9E-10 T 23-10-2018 VMUT_0410 f33cf370e53ebc3ce105418c51b126eb 296 SUPERFAMILY SSF161098 57 283 5.89E-60 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_0410 f33cf370e53ebc3ce105418c51b126eb 296 Gene3D G3DSA:1.10.3720.10 52 293 6.5E-69 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_0410 f33cf370e53ebc3ce105418c51b126eb 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 286 1.1E-15 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VMUT_1278 79691bd416e1d7b6677ef6f2368520d9 95 Pfam PF01990 ATP synthase (F/14-kDa) subunit 1 77 3.1E-16 T 23-10-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 VMUT_1278 79691bd416e1d7b6677ef6f2368520d9 95 SUPERFAMILY SSF159468 1 94 3.14E-16 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 VMUT_1278 79691bd416e1d7b6677ef6f2368520d9 95 Gene3D G3DSA:3.40.50.10580 1 94 4.1E-16 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 VMUT_1238 be6a69bcbe2f44c583f9ce0529406363 383 SUPERFAMILY SSF51604 122 381 1.24E-79 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VMUT_1238 be6a69bcbe2f44c583f9ce0529406363 383 Gene3D G3DSA:3.30.390.10 1 132 9.1E-35 T 23-10-2018 IPR029017 Enolase-like, N-terminal VMUT_1238 be6a69bcbe2f44c583f9ce0529406363 383 Pfam PF13378 Enolase C-terminal domain-like 157 375 3.3E-60 T 23-10-2018 IPR029065 Enolase C-terminal domain-like VMUT_1238 be6a69bcbe2f44c583f9ce0529406363 383 Gene3D G3DSA:3.20.20.120 133 382 1.5E-84 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VMUT_1238 be6a69bcbe2f44c583f9ce0529406363 383 SUPERFAMILY SSF54826 1 139 3.54E-30 T 23-10-2018 VMUT_1238 be6a69bcbe2f44c583f9ce0529406363 383 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 109 134 - T 23-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 VMUT_1238 be6a69bcbe2f44c583f9ce0529406363 383 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 30 134 8.1E-17 T 23-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain VMUT_1238 be6a69bcbe2f44c583f9ce0529406363 383 SMART SM00922 153 249 2.7E-29 T 23-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal VMUT_0192 1872e72f6dbab369efb569b9bd157473 374 SUPERFAMILY SSF52374 1 356 1.13E-58 T 23-10-2018 VMUT_0192 1872e72f6dbab369efb569b9bd157473 374 Hamap MF_02009 Tyrosine--tRNA ligase [tyrS]. 5 355 42.519 T 23-10-2018 IPR023678 Tyrosine-tRNA ligase, type 4 GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 VMUT_0192 1872e72f6dbab369efb569b9bd157473 374 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 183 204 3.4E-5 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 VMUT_0192 1872e72f6dbab369efb569b9bd157473 374 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 105 124 3.4E-5 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 VMUT_0192 1872e72f6dbab369efb569b9bd157473 374 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 245 255 3.4E-5 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 VMUT_0192 1872e72f6dbab369efb569b9bd157473 374 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 46 62 3.4E-5 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 VMUT_0192 1872e72f6dbab369efb569b9bd157473 374 PIRSF PIRSF006588 1 372 4.2E-109 T 23-10-2018 IPR023617 Tyrosine-tRNA ligase, archaeal/eukaryotic-type GO:0004831 KEGG: 00970+6.1.1.1 VMUT_0192 1872e72f6dbab369efb569b9bd157473 374 Pfam PF00579 tRNA synthetases class I (W and Y) 32 347 2.3E-39 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_0192 1872e72f6dbab369efb569b9bd157473 374 Gene3D G3DSA:3.40.50.620 1 227 5.3E-56 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_0192 1872e72f6dbab369efb569b9bd157473 374 Gene3D G3DSA:1.10.240.10 229 370 1.6E-38 T 23-10-2018 VMUT_0297 7ef5f83e3533654453edca8e00376bd9 520 SMART SM00382 327 450 0.0048 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0297 7ef5f83e3533654453edca8e00376bd9 520 SUPERFAMILY SSF52540 193 442 4.81E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0297 7ef5f83e3533654453edca8e00376bd9 520 Pfam PF00437 Type II/IV secretion system protein 212 446 4.1E-18 T 23-10-2018 IPR001482 Type II/IV secretion system protein VMUT_0297 7ef5f83e3533654453edca8e00376bd9 520 Gene3D G3DSA:3.30.450.380 148 274 1.5E-6 T 23-10-2018 VMUT_0297 7ef5f83e3533654453edca8e00376bd9 520 Gene3D G3DSA:3.40.50.300 299 519 9.5E-27 T 23-10-2018 VMUT_1348 6334329822ef10e1226774dfdf3e7bc7 197 PIRSF PIRSF002161 10 195 6.2E-46 T 23-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1348 6334329822ef10e1226774dfdf3e7bc7 197 SUPERFAMILY SSF55282 30 194 5.89E-49 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1348 6334329822ef10e1226774dfdf3e7bc7 197 Pfam PF00281 Ribosomal protein L5 31 83 3.5E-18 T 23-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1348 6334329822ef10e1226774dfdf3e7bc7 197 Gene3D G3DSA:3.30.1440.10 27 197 1.1E-62 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1348 6334329822ef10e1226774dfdf3e7bc7 197 Pfam PF00673 ribosomal L5P family C-terminus 87 186 1.1E-19 T 23-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1348 6334329822ef10e1226774dfdf3e7bc7 197 Hamap MF_01333_A 50S ribosomal protein L5 [rplE]. 29 196 36.869 T 23-10-2018 IPR022804 Ribosomal protein L5, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_0341 aaaa4d5d1e7c9a9df8724f2e1e02bae6 557 SUPERFAMILY SSF161098 339 525 1.27E-15 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_0341 aaaa4d5d1e7c9a9df8724f2e1e02bae6 557 SUPERFAMILY SSF161098 15 205 7.33E-17 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_0341 aaaa4d5d1e7c9a9df8724f2e1e02bae6 557 Gene3D G3DSA:1.10.3720.10 5 213 9.8E-14 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_0341 aaaa4d5d1e7c9a9df8724f2e1e02bae6 557 Gene3D G3DSA:1.10.3720.10 334 542 2.1E-18 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_0341 aaaa4d5d1e7c9a9df8724f2e1e02bae6 557 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 214 4.0E-10 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VMUT_0341 aaaa4d5d1e7c9a9df8724f2e1e02bae6 557 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 353 534 2.8E-14 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VMUT_1095 7b53a9e3f12a1d64ad342b7c90fdf585 209 SUPERFAMILY SSF53756 7 207 3.53E-43 T 23-10-2018 VMUT_1095 7b53a9e3f12a1d64ad342b7c90fdf585 209 Gene3D G3DSA:3.40.50.2000 7 202 3.8E-36 T 23-10-2018 VMUT_1095 7b53a9e3f12a1d64ad342b7c90fdf585 209 Gene3D G3DSA:3.40.50.2000 17 186 3.8E-36 T 23-10-2018 VMUT_1095 7b53a9e3f12a1d64ad342b7c90fdf585 209 Pfam PF00534 Glycosyl transferases group 1 28 185 4.6E-26 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 VMUT_0727 26aec7d92d0223c955aae264fa49cce9 237 Gene3D G3DSA:3.30.1490.20 39 116 6.0E-83 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VMUT_0727 26aec7d92d0223c955aae264fa49cce9 237 Gene3D G3DSA:3.30.470.20 20 231 6.0E-83 T 23-10-2018 VMUT_0727 26aec7d92d0223c955aae264fa49cce9 237 Pfam PF13549 ATP-grasp domain 12 233 7.6E-77 T 23-10-2018 VMUT_0727 26aec7d92d0223c955aae264fa49cce9 237 SUPERFAMILY SSF56059 20 234 2.83E-44 T 23-10-2018 VMUT_0427 7030db3fb334083362ad3c32174c5418 636 SUPERFAMILY SSF54211 43 225 9.48E-23 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VMUT_0427 7030db3fb334083362ad3c32174c5418 636 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 102 184 4.1E-10 T 23-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 VMUT_0427 7030db3fb334083362ad3c32174c5418 636 Gene3D G3DSA:3.30.230.10 40 237 1.3E-23 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup VMUT_1865 746bc7df24ffbf7efda4dea2dae36e4d 567 SMART SM00382 179 445 4.5E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_1865 746bc7df24ffbf7efda4dea2dae36e4d 567 SUPERFAMILY SSF52540 174 475 2.13E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1865 746bc7df24ffbf7efda4dea2dae36e4d 567 Pfam PF12846 AAA-like domain 381 461 4.3E-7 T 23-10-2018 VMUT_1865 746bc7df24ffbf7efda4dea2dae36e4d 567 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 381 390 - T 23-10-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site VMUT_1865 746bc7df24ffbf7efda4dea2dae36e4d 567 Gene3D G3DSA:3.40.50.300 295 484 6.8E-16 T 23-10-2018 VMUT_1865 746bc7df24ffbf7efda4dea2dae36e4d 567 Pfam PF01935 Domain of unknown function DUF87 170 310 2.7E-15 T 23-10-2018 IPR002789 Helicase HerA, central domain VMUT_1865 746bc7df24ffbf7efda4dea2dae36e4d 567 Gene3D G3DSA:3.40.50.300 163 239 1.4E-11 T 23-10-2018 VMUT_0921 272ebf7ffa3febde6fb7f9f6b59dffc7 257 Pfam PF00005 ABC transporter 24 165 1.7E-25 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_0921 272ebf7ffa3febde6fb7f9f6b59dffc7 257 SUPERFAMILY SSF52540 7 226 2.3E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0921 272ebf7ffa3febde6fb7f9f6b59dffc7 257 Gene3D G3DSA:3.40.50.300 3 252 3.0E-51 T 23-10-2018 VMUT_0921 272ebf7ffa3febde6fb7f9f6b59dffc7 257 SMART SM00382 32 213 4.7E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_1940 b70849cff7eb7ffa02f577cb643ea502 491 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 5 109 1.3E-18 T 23-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 VMUT_1940 b70849cff7eb7ffa02f577cb643ea502 491 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 111 316 7.9E-42 T 23-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 VMUT_1940 b70849cff7eb7ffa02f577cb643ea502 491 SUPERFAMILY SSF52440 4 109 7.91E-18 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily VMUT_1940 b70849cff7eb7ffa02f577cb643ea502 491 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 5 449 1.1E-93 T 23-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 VMUT_1940 b70849cff7eb7ffa02f577cb643ea502 491 SMART SM01209 110 316 5.9E-60 T 23-10-2018 VMUT_1940 b70849cff7eb7ffa02f577cb643ea502 491 Gene3D G3DSA:3.40.50.20 4 102 8.6E-18 T 23-10-2018 VMUT_1940 b70849cff7eb7ffa02f577cb643ea502 491 Gene3D G3DSA:3.30.470.20 208 349 3.3E-37 T 23-10-2018 VMUT_1940 b70849cff7eb7ffa02f577cb643ea502 491 SUPERFAMILY SSF56059 111 342 9.49E-33 T 23-10-2018 VMUT_1940 b70849cff7eb7ffa02f577cb643ea502 491 SMART SM01210 351 449 4.7E-6 T 23-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 VMUT_1940 b70849cff7eb7ffa02f577cb643ea502 491 SUPERFAMILY SSF51246 352 449 5.49E-7 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 VMUT_0279 91974c8a274977eabd31f00a715b5405 410 Gene3D G3DSA:3.40.50.720 172 410 2.3E-82 T 23-10-2018 VMUT_0279 91974c8a274977eabd31f00a715b5405 410 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 174 408 1.7E-72 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 VMUT_0279 91974c8a274977eabd31f00a715b5405 410 SMART SM00839 172 408 3.5E-92 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 VMUT_0279 91974c8a274977eabd31f00a715b5405 410 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 82 96 5.7E-26 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 VMUT_0279 91974c8a274977eabd31f00a715b5405 410 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 333 344 5.7E-26 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 VMUT_0279 91974c8a274977eabd31f00a715b5405 410 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 204 224 5.7E-26 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 VMUT_0279 91974c8a274977eabd31f00a715b5405 410 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 162 184 5.7E-26 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 VMUT_0279 91974c8a274977eabd31f00a715b5405 410 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 25 153 5.0E-54 T 23-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 VMUT_0279 91974c8a274977eabd31f00a715b5405 410 Gene3D G3DSA:3.40.50.10860 27 170 2.2E-63 T 23-10-2018 VMUT_0279 91974c8a274977eabd31f00a715b5405 410 PIRSF PIRSF000185 1 410 5.7E-167 T 23-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 VMUT_0279 91974c8a274977eabd31f00a715b5405 410 SUPERFAMILY SSF51735 173 409 1.54E-72 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0279 91974c8a274977eabd31f00a715b5405 410 SUPERFAMILY SSF53223 3 172 3.84E-64 T 23-10-2018 VMUT_0810 94b6992a1ee312b10d4b347cce31ada0 225 TIGRFAM TIGR02076 pyrH_arch: putative uridylate kinase 8 223 8.6E-65 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 VMUT_0810 94b6992a1ee312b10d4b347cce31ada0 225 SUPERFAMILY SSF53633 8 224 7.59E-35 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily VMUT_0810 94b6992a1ee312b10d4b347cce31ada0 225 Gene3D G3DSA:3.40.1160.10 7 225 1.8E-46 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily VMUT_0810 94b6992a1ee312b10d4b347cce31ada0 225 Pfam PF00696 Amino acid kinase family 8 201 9.6E-26 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 VMUT_0915 52ec1935e89cd3370fa58931022a9061 178 PIRSF PIRSF006373 10 177 9.1E-32 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 VMUT_0915 52ec1935e89cd3370fa58931022a9061 178 Gene3D G3DSA:1.10.10.10 14 98 2.1E-13 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_0915 52ec1935e89cd3370fa58931022a9061 178 Hamap MF_01909 Transcription factor E [tfe]. 4 175 17.177 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 VMUT_0915 52ec1935e89cd3370fa58931022a9061 178 Pfam PF02002 TFIIE alpha subunit 26 116 4.2E-8 T 23-10-2018 IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 VMUT_0915 52ec1935e89cd3370fa58931022a9061 178 SUPERFAMILY SSF46785 17 97 1.01E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0915 52ec1935e89cd3370fa58931022a9061 178 SMART SM00531 29 167 2.6E-5 T 23-10-2018 IPR002853 Transcription initiation factor IIE subunit alpha, N-terminal GO:0006367 Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 VMUT_0635 3dfb29d5e4302cdc3f613b48a32c6552 1137 Gene3D G3DSA:3.30.70.20 922 978 2.7E-13 T 23-10-2018 VMUT_0635 3dfb29d5e4302cdc3f613b48a32c6552 1137 Pfam PF12831 FAD dependent oxidoreductase 6 43 1.9E-7 T 23-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal VMUT_0635 3dfb29d5e4302cdc3f613b48a32c6552 1137 Pfam PF00890 FAD binding domain 594 628 1.8E-4 T 23-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 VMUT_0635 3dfb29d5e4302cdc3f613b48a32c6552 1137 Gene3D G3DSA:3.50.50.60 701 839 3.7E-30 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0635 3dfb29d5e4302cdc3f613b48a32c6552 1137 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 753 899 1.4E-6 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VMUT_0635 3dfb29d5e4302cdc3f613b48a32c6552 1137 Gene3D G3DSA:3.50.50.60 366 420 8.5E-7 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0635 3dfb29d5e4302cdc3f613b48a32c6552 1137 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 929 940 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_0635 3dfb29d5e4302cdc3f613b48a32c6552 1137 Gene3D G3DSA:3.50.50.60 292 365 8.5E-7 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0635 3dfb29d5e4302cdc3f613b48a32c6552 1137 Gene3D G3DSA:3.50.50.60 595 903 3.7E-30 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0635 3dfb29d5e4302cdc3f613b48a32c6552 1137 SUPERFAMILY SSF51905 575 906 2.59E-30 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0635 3dfb29d5e4302cdc3f613b48a32c6552 1137 SUPERFAMILY SSF51905 4 432 3.67E-27 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0635 3dfb29d5e4302cdc3f613b48a32c6552 1137 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 959 970 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_0635 3dfb29d5e4302cdc3f613b48a32c6552 1137 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 690 698 4.9E-6 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VMUT_0635 3dfb29d5e4302cdc3f613b48a32c6552 1137 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 593 615 4.9E-6 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VMUT_0635 3dfb29d5e4302cdc3f613b48a32c6552 1137 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 875 893 4.9E-6 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VMUT_0635 3dfb29d5e4302cdc3f613b48a32c6552 1137 SUPERFAMILY SSF54862 913 986 9.21E-20 T 23-10-2018 VMUT_0635 3dfb29d5e4302cdc3f613b48a32c6552 1137 Pfam PF02662 Methyl-viologen-reducing hydrogenase, delta subunit 1000 1119 4.3E-36 T 23-10-2018 IPR003813 F420-non-reducing hydrogenase iron-sulfur subunit D GO:0055114 VMUT_0635 3dfb29d5e4302cdc3f613b48a32c6552 1137 Gene3D G3DSA:3.30.70.3270 86 210 1.7E-5 T 23-10-2018 VMUT_0635 3dfb29d5e4302cdc3f613b48a32c6552 1137 Pfam PF00037 4Fe-4S binding domain 100 118 9.8E-5 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_0635 3dfb29d5e4302cdc3f613b48a32c6552 1137 Pfam PF00037 4Fe-4S binding domain 954 975 2.7E-5 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_0635 3dfb29d5e4302cdc3f613b48a32c6552 1137 Pfam PF00037 4Fe-4S binding domain 922 945 3.9E-9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_0635 3dfb29d5e4302cdc3f613b48a32c6552 1137 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 105 116 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_0635 3dfb29d5e4302cdc3f613b48a32c6552 1137 Gene3D G3DSA:3.40.50.720 2 78 2.6E-11 T 23-10-2018 VMUT_1211 49550a150381dcf9e381d57d4396e8ed 184 Hamap MF_01331_A 50S ribosomal protein L22 [rplV]. 17 168 29.942 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1211 49550a150381dcf9e381d57d4396e8ed 184 Gene3D G3DSA:3.90.470.10 21 183 4.0E-39 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 VMUT_1211 49550a150381dcf9e381d57d4396e8ed 184 SUPERFAMILY SSF54843 22 163 4.06E-40 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 VMUT_1211 49550a150381dcf9e381d57d4396e8ed 184 TIGRFAM TIGR01038 uL22_arch_euk: ribosomal protein uL22 27 164 5.0E-48 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1211 49550a150381dcf9e381d57d4396e8ed 184 Pfam PF00237 Ribosomal protein L22p/L17e 35 163 1.6E-26 T 23-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 VMUT_1376 0cd835455353edfe9de97f1e47472d07 404 SUPERFAMILY SSF53901 4 228 4.01E-43 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_1376 0cd835455353edfe9de97f1e47472d07 404 Gene3D G3DSA:3.40.47.10 3 393 1.0E-115 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_1376 0cd835455353edfe9de97f1e47472d07 404 PIRSF PIRSF000429 1 391 7.2E-57 T 23-10-2018 IPR002155 Thiolase GO:0016747 VMUT_1376 0cd835455353edfe9de97f1e47472d07 404 SUPERFAMILY SSF53901 232 390 1.67E-25 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_1376 0cd835455353edfe9de97f1e47472d07 404 Pfam PF00108 Thiolase, N-terminal domain 5 183 7.3E-17 T 23-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 VMUT_1376 0cd835455353edfe9de97f1e47472d07 404 Pfam PF02803 Thiolase, C-terminal domain 247 357 1.5E-6 T 23-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 VMUT_1782 f9b515dccb630422a9bd4c725ca69528 154 Gene3D G3DSA:3.30.70.920 60 152 1.9E-21 T 23-10-2018 VMUT_1782 f9b515dccb630422a9bd4c725ca69528 154 SMART SM00344 7 115 6.2E-31 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 VMUT_1782 f9b515dccb630422a9bd4c725ca69528 154 Pfam PF01037 Lrp/AsnC ligand binding domain 77 144 1.9E-11 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain VMUT_1782 f9b515dccb630422a9bd4c725ca69528 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 2.0E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VMUT_1782 f9b515dccb630422a9bd4c725ca69528 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 2.0E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VMUT_1782 f9b515dccb630422a9bd4c725ca69528 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 2.0E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VMUT_1782 f9b515dccb630422a9bd4c725ca69528 154 SUPERFAMILY SSF46785 7 66 6.93E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_1782 f9b515dccb630422a9bd4c725ca69528 154 SUPERFAMILY SSF54909 70 154 4.69E-15 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel VMUT_1782 f9b515dccb630422a9bd4c725ca69528 154 Pfam PF13412 Winged helix-turn-helix DNA-binding 8 53 3.0E-15 T 23-10-2018 VMUT_1782 f9b515dccb630422a9bd4c725ca69528 154 Gene3D G3DSA:1.10.10.10 7 58 2.3E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_2111 35be1afa120ad48123f5a18d859afb5f 189 Hamap MF_00975 Exosome complex component Csl4 [csl4]. 5 188 25.748 T 23-10-2018 IPR030850 Exosome complex component Csl4, archaea GO:0000178|GO:0006396 VMUT_2111 35be1afa120ad48123f5a18d859afb5f 189 SUPERFAMILY SSF50249 59 182 6.66E-21 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold VMUT_2111 35be1afa120ad48123f5a18d859afb5f 189 Gene3D G3DSA:2.40.50.100 3 54 2.6E-10 T 23-10-2018 VMUT_2111 35be1afa120ad48123f5a18d859afb5f 189 SMART SM00316 75 143 1.8E-4 T 23-10-2018 IPR022967 RNA-binding domain, S1 VMUT_2111 35be1afa120ad48123f5a18d859afb5f 189 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 5 42 9.3E-7 T 23-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 VMUT_2111 35be1afa120ad48123f5a18d859afb5f 189 Gene3D G3DSA:2.40.50.140 60 149 2.0E-16 T 23-10-2018 VMUT_2111 35be1afa120ad48123f5a18d859afb5f 189 Gene3D G3DSA:2.20.70.10 150 184 9.5E-7 T 23-10-2018 VMUT_2111 35be1afa120ad48123f5a18d859afb5f 189 SUPERFAMILY SSF110324 4 56 6.58E-9 T 23-10-2018 VMUT_1690 b6a352290836694891d2c194c411175d 171 Pfam PF01467 Cytidylyltransferase-like 5 84 2.0E-12 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 VMUT_1690 b6a352290836694891d2c194c411175d 171 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 171 66.234 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 VMUT_1690 b6a352290836694891d2c194c411175d 171 Gene3D G3DSA:3.40.50.620 2 171 7.5E-39 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_1690 b6a352290836694891d2c194c411175d 171 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 62 1.6E-11 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 VMUT_1690 b6a352290836694891d2c194c411175d 171 SUPERFAMILY SSF52374 3 163 2.95E-24 T 23-10-2018 VMUT_0683 da14666234ae4de8ef4bea255046c454 598 TIGRFAM TIGR00491 aIF-2: translation initiation factor aIF-2 12 595 9.9E-221 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 VMUT_0683 da14666234ae4de8ef4bea255046c454 598 Gene3D G3DSA:3.40.50.300 9 235 2.5E-55 T 23-10-2018 VMUT_0683 da14666234ae4de8ef4bea255046c454 598 SUPERFAMILY SSF52540 12 290 2.13E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0683 da14666234ae4de8ef4bea255046c454 598 PRINTS PR00315 GTP-binding elongation factor signature 99 110 2.5E-8 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VMUT_0683 da14666234ae4de8ef4bea255046c454 598 PRINTS PR00315 GTP-binding elongation factor signature 15 28 2.5E-8 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VMUT_0683 da14666234ae4de8ef4bea255046c454 598 PRINTS PR00315 GTP-binding elongation factor signature 135 144 2.5E-8 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VMUT_0683 da14666234ae4de8ef4bea255046c454 598 PRINTS PR00315 GTP-binding elongation factor signature 83 93 2.5E-8 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VMUT_0683 da14666234ae4de8ef4bea255046c454 598 Pfam PF00009 Elongation factor Tu GTP binding domain 17 222 3.7E-27 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VMUT_0683 da14666234ae4de8ef4bea255046c454 598 SUPERFAMILY SSF52156 342 466 5.49E-30 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily VMUT_0683 da14666234ae4de8ef4bea255046c454 598 Gene3D G3DSA:2.40.30.10 474 563 2.6E-34 T 23-10-2018 VMUT_0683 da14666234ae4de8ef4bea255046c454 598 Gene3D G3DSA:3.40.50.10050 358 463 1.9E-32 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily VMUT_0683 da14666234ae4de8ef4bea255046c454 598 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 17 153 7.7E-15 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 VMUT_0683 da14666234ae4de8ef4bea255046c454 598 Pfam PF11987 Translation-initiation factor 2 351 453 6.8E-18 T 23-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 VMUT_0683 da14666234ae4de8ef4bea255046c454 598 Hamap MF_00100_A Translation initiation factor IF-2 [infB]. 9 598 40.914 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 VMUT_0683 da14666234ae4de8ef4bea255046c454 598 Pfam PF14578 Elongation factor Tu domain 4 474 560 1.2E-38 T 23-10-2018 IPR029459 Elongation factor Tu-type domain VMUT_0683 da14666234ae4de8ef4bea255046c454 598 Pfam PF03144 Elongation factor Tu domain 2 255 333 3.2E-7 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 VMUT_0683 da14666234ae4de8ef4bea255046c454 598 Gene3D G3DSA:2.40.30.10 241 357 2.1E-33 T 23-10-2018 VMUT_0683 da14666234ae4de8ef4bea255046c454 598 SUPERFAMILY SSF50447 473 594 4.64E-30 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VMUT_2241 30216c30cb5b7468d80b3e3b1aabc3b7 296 Pfam PF00348 Polyprenyl synthetase 41 231 3.0E-46 T 23-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 VMUT_2241 30216c30cb5b7468d80b3e3b1aabc3b7 296 Gene3D G3DSA:1.10.600.10 17 295 1.8E-55 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily VMUT_2241 30216c30cb5b7468d80b3e3b1aabc3b7 296 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 92 106 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site VMUT_2241 30216c30cb5b7468d80b3e3b1aabc3b7 296 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 215 227 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site VMUT_2241 30216c30cb5b7468d80b3e3b1aabc3b7 296 SUPERFAMILY SSF48576 23 233 3.24E-53 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily VMUT_1055 4ff2063068299dd9db84ba8caf8a7f1b 112 SUPERFAMILY SSF53756 2 108 1.05E-24 T 23-10-2018 VMUT_1055 4ff2063068299dd9db84ba8caf8a7f1b 112 Gene3D G3DSA:3.40.50.2000 1 112 1.0E-20 T 23-10-2018 VMUT_1055 4ff2063068299dd9db84ba8caf8a7f1b 112 Pfam PF00534 Glycosyl transferases group 1 17 107 3.9E-14 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 VMUT_1221 025adab08432d81ae5f283421afab74a 200 Pfam PF01022 Bacterial regulatory protein, arsR family 43 86 3.5E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VMUT_1221 025adab08432d81ae5f283421afab74a 200 Gene3D G3DSA:1.10.10.10 23 102 2.7E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_1221 025adab08432d81ae5f283421afab74a 200 SUPERFAMILY SSF46785 36 91 1.67E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_1878 838534a77702b67bdf7e580d4705df98 261 SUPERFAMILY SSF103473 82 250 3.27E-7 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_1878 838534a77702b67bdf7e580d4705df98 261 Gene3D G3DSA:1.20.1250.20 54 252 9.1E-6 T 23-10-2018 VMUT_1504 55c14ae985d24cbeed8ef591f6cde80c 259 Gene3D G3DSA:3.40.50.300 3 252 1.1E-26 T 23-10-2018 VMUT_1504 55c14ae985d24cbeed8ef591f6cde80c 259 SUPERFAMILY SSF52540 1 246 2.31E-24 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1504 55c14ae985d24cbeed8ef591f6cde80c 259 Pfam PF13614 AAA domain 4 161 3.5E-14 T 23-10-2018 IPR025669 AAA domain VMUT_2290 19e9be3c81eff9fdf2d3d1c7da0966c9 583 Gene3D G3DSA:3.40.50.12780 10 453 1.6E-119 T 23-10-2018 VMUT_2290 19e9be3c81eff9fdf2d3d1c7da0966c9 583 Pfam PF13193 AMP-binding enzyme C-terminal domain 468 546 4.8E-20 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VMUT_2290 19e9be3c81eff9fdf2d3d1c7da0966c9 583 SUPERFAMILY SSF56801 23 559 1.27E-137 T 23-10-2018 VMUT_2290 19e9be3c81eff9fdf2d3d1c7da0966c9 583 Gene3D G3DSA:3.30.300.30 455 575 3.6E-25 T 23-10-2018 VMUT_2290 19e9be3c81eff9fdf2d3d1c7da0966c9 583 Pfam PF00501 AMP-binding enzyme 54 459 7.7E-77 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VMUT_0293 eb2a5208b1268a5840b3195364deb29d 152 SUPERFAMILY SSF53335 3 128 1.24E-20 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_0293 eb2a5208b1268a5840b3195364deb29d 152 Gene3D G3DSA:3.40.50.150 1 152 5.7E-36 T 23-10-2018 VMUT_1550 6e6c53271d31efb31590c62201097e1d 103 SUPERFAMILY SSF54999 4 101 9.29E-28 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily VMUT_1550 6e6c53271d31efb31590c62201097e1d 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 2 101 22.95 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1550 6e6c53271d31efb31590c62201097e1d 103 Pfam PF00338 Ribosomal protein S10p/S20e 6 99 1.0E-25 T 23-10-2018 IPR027486 Ribosomal protein S10 domain VMUT_1550 6e6c53271d31efb31590c62201097e1d 103 Gene3D G3DSA:3.30.70.600 2 102 2.7E-29 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily VMUT_1550 6e6c53271d31efb31590c62201097e1d 103 TIGRFAM TIGR01046 uS10_euk_arch: ribosomal protein uS10 4 101 1.1E-39 T 23-10-2018 IPR005729 Ribosomal protein S10, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1550 6e6c53271d31efb31590c62201097e1d 103 PRINTS PR00971 Ribosomal protein S10 family signature 4 17 2.4E-13 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1550 6e6c53271d31efb31590c62201097e1d 103 PRINTS PR00971 Ribosomal protein S10 family signature 39 54 2.4E-13 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1550 6e6c53271d31efb31590c62201097e1d 103 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 2.4E-13 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1550 6e6c53271d31efb31590c62201097e1d 103 SMART SM01403 6 100 1.2E-39 T 23-10-2018 IPR027486 Ribosomal protein S10 domain VMUT_0910 c67628b23b29aa310bf1f9364f9df9f1 305 SUPERFAMILY SSF47364 1 90 9.16E-10 T 23-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 VMUT_0910 c67628b23b29aa310bf1f9364f9df9f1 305 SMART SM00382 109 285 2.7E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0910 c67628b23b29aa310bf1f9364f9df9f1 305 Pfam PF02881 SRP54-type protein, helical bundle domain 12 59 5.5E-6 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 VMUT_0910 c67628b23b29aa310bf1f9364f9df9f1 305 SMART SM00963 4 89 0.0033 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 VMUT_0910 c67628b23b29aa310bf1f9364f9df9f1 305 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 31 303 1.3E-89 T 23-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 VMUT_0910 c67628b23b29aa310bf1f9364f9df9f1 305 Pfam PF00448 SRP54-type protein, GTPase domain 111 304 7.2E-67 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 VMUT_0910 c67628b23b29aa310bf1f9364f9df9f1 305 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 278 291 - T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 VMUT_0910 c67628b23b29aa310bf1f9364f9df9f1 305 SUPERFAMILY SSF52540 106 299 1.17E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0910 c67628b23b29aa310bf1f9364f9df9f1 305 SMART SM00962 110 305 5.2E-87 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 VMUT_0910 c67628b23b29aa310bf1f9364f9df9f1 305 Gene3D G3DSA:1.20.120.140 3 90 2.3E-13 T 23-10-2018 VMUT_0910 c67628b23b29aa310bf1f9364f9df9f1 305 Gene3D G3DSA:3.40.50.300 94 304 3.8E-71 T 23-10-2018 VMUT_1166 97ad2a59a49fac7a7c9aec49be138662 590 Pfam PF12146 Serine aminopeptidase, S33 65 168 1.4E-9 T 23-10-2018 IPR022742 Serine aminopeptidase, S33 VMUT_1166 97ad2a59a49fac7a7c9aec49be138662 590 SUPERFAMILY SSF53474 36 277 1.47E-27 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold VMUT_1166 97ad2a59a49fac7a7c9aec49be138662 590 Gene3D G3DSA:3.40.50.1820 28 275 1.3E-25 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold VMUT_0797 57d6b3ee839d4e9e4a5abd665d454a54 409 Gene3D G3DSA:1.20.140.10 247 399 2.2E-45 T 23-10-2018 VMUT_0797 57d6b3ee839d4e9e4a5abd665d454a54 409 SUPERFAMILY SSF56645 10 250 1.02E-77 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VMUT_0797 57d6b3ee839d4e9e4a5abd665d454a54 409 SUPERFAMILY SSF47203 240 394 3.22E-49 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VMUT_0797 57d6b3ee839d4e9e4a5abd665d454a54 409 Gene3D G3DSA:1.10.540.10 7 129 4.0E-36 T 23-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VMUT_0797 57d6b3ee839d4e9e4a5abd665d454a54 409 Gene3D G3DSA:2.40.110.10 130 246 5.2E-41 T 23-10-2018 VMUT_0797 57d6b3ee839d4e9e4a5abd665d454a54 409 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 241 388 4.3E-40 T 23-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VMUT_0797 57d6b3ee839d4e9e4a5abd665d454a54 409 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 349 368 - T 23-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 VMUT_0797 57d6b3ee839d4e9e4a5abd665d454a54 409 PIRSF PIRSF016578 15 391 4.9E-17 T 23-10-2018 VMUT_0797 57d6b3ee839d4e9e4a5abd665d454a54 409 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 17 127 1.1E-32 T 23-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VMUT_0797 57d6b3ee839d4e9e4a5abd665d454a54 409 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 132 229 4.1E-25 T 23-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VMUT_1220 ecda7ba755fb2981394d80dab9a09214 202 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 20 194 2.0E-72 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 VMUT_1220 ecda7ba755fb2981394d80dab9a09214 202 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 20 192 1.2E-72 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 VMUT_1220 ecda7ba755fb2981394d80dab9a09214 202 Gene3D G3DSA:2.60.120.10 19 201 2.1E-70 T 23-10-2018 IPR014710 RmlC-like jelly roll fold VMUT_1220 ecda7ba755fb2981394d80dab9a09214 202 SUPERFAMILY SSF51182 20 200 3.44E-73 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily VMUT_1220 ecda7ba755fb2981394d80dab9a09214 202 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 23 192 5.6E-68 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 VMUT_2156 37867bccde1f86be6be1e8f24431411f 264 Gene3D G3DSA:3.40.980.10 4 173 9.3E-51 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily VMUT_2156 37867bccde1f86be6be1e8f24431411f 264 Pfam PF00994 Probable molybdopterin binding domain 7 172 3.0E-32 T 23-10-2018 IPR001453 MoaB/Mog domain VMUT_2156 37867bccde1f86be6be1e8f24431411f 264 SUPERFAMILY SSF53218 4 201 2.49E-38 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily VMUT_2156 37867bccde1f86be6be1e8f24431411f 264 SMART SM00852 6 173 1.9E-33 T 23-10-2018 IPR001453 MoaB/Mog domain VMUT_1858 b4aa9a2b3c8c509f853b67c34c0a2594 388 Gene3D G3DSA:3.20.20.140 56 330 7.1E-29 T 23-10-2018 VMUT_1858 b4aa9a2b3c8c509f853b67c34c0a2594 388 SUPERFAMILY SSF51338 9 64 2.91E-5 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VMUT_1858 b4aa9a2b3c8c509f853b67c34c0a2594 388 SUPERFAMILY SSF51556 54 329 5.11E-31 T 23-10-2018 IPR032466 Metal-dependent hydrolase VMUT_1858 b4aa9a2b3c8c509f853b67c34c0a2594 388 Pfam PF01979 Amidohydrolase family 51 312 7.6E-11 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VMUT_0653 ff25468ed0ecec19932da6106d2fadca 222 TIGRFAM TIGR01028 uS7_euk_arch: ribosomal protein uS7 38 222 1.4E-82 T 23-10-2018 IPR005716 Ribosomal protein S5/S7, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0653 ff25468ed0ecec19932da6106d2fadca 222 Gene3D G3DSA:1.10.455.10 18 222 4.6E-85 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily VMUT_0653 ff25468ed0ecec19932da6106d2fadca 222 Pfam PF00177 Ribosomal protein S7p/S5e 81 222 3.5E-43 T 23-10-2018 IPR023798 Ribosomal protein S7 domain VMUT_0653 ff25468ed0ecec19932da6106d2fadca 222 SUPERFAMILY SSF47973 38 222 5.36E-66 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily VMUT_0653 ff25468ed0ecec19932da6106d2fadca 222 ProSitePatterns PS00052 Ribosomal protein S7 signature. 88 114 - T 23-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0653 ff25468ed0ecec19932da6106d2fadca 222 Hamap MF_00480_A 30S ribosomal protein S7 [rpsG]. 38 222 40.184 T 23-10-2018 IPR026018 Ribosomal protein S7, archaeal VMUT_0653 ff25468ed0ecec19932da6106d2fadca 222 PIRSF PIRSF002122 6 222 1.3E-50 T 23-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 VMUT_0406 8b8fd2564c7763f82aa4e33def710229 180 SMART SM00347 4 90 0.0081 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VMUT_0406 8b8fd2564c7763f82aa4e33def710229 180 Gene3D G3DSA:1.10.10.10 2 114 1.7E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_0406 8b8fd2564c7763f82aa4e33def710229 180 SMART SM00746 134 169 1.8E-6 T 23-10-2018 IPR011017 TRASH domain VMUT_0406 8b8fd2564c7763f82aa4e33def710229 180 Pfam PF13412 Winged helix-turn-helix DNA-binding 11 56 5.9E-14 T 23-10-2018 VMUT_0406 8b8fd2564c7763f82aa4e33def710229 180 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 11 27 2.9E-8 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VMUT_0406 8b8fd2564c7763f82aa4e33def710229 180 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 38 57 2.9E-8 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VMUT_0406 8b8fd2564c7763f82aa4e33def710229 180 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 27 38 2.9E-8 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VMUT_0406 8b8fd2564c7763f82aa4e33def710229 180 SUPERFAMILY SSF46785 8 56 2.06E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0406 8b8fd2564c7763f82aa4e33def710229 180 Pfam PF08394 Archaeal TRASH domain 134 169 9.8E-14 T 23-10-2018 IPR013603 TRASH transcription regulator C-terminal, archaeal VMUT_0742 237915e95322601af6a9c71aa8db7c60 653 SUPERFAMILY SSF54897 46 142 1.51E-9 T 23-10-2018 VMUT_0742 237915e95322601af6a9c71aa8db7c60 653 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 538 548 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site VMUT_0742 237915e95322601af6a9c71aa8db7c60 653 Gene3D G3DSA:3.40.50.200 215 640 5.4E-70 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 VMUT_0742 237915e95322601af6a9c71aa8db7c60 653 SMART SM00944 36 190 0.0047 T 23-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 VMUT_0742 237915e95322601af6a9c71aa8db7c60 653 SUPERFAMILY SSF52743 233 637 1.44E-45 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 VMUT_0468 7ecc49c387340b06483c7fb578554bbc 94 ProDom PD002841 RIBOSOMAL RIBONUCLEOPROTEIN 60S L44 L44E L41 RESISTANCE 50S ANTIBIOTIC CYCLOHEXIMIDE 9 92 1.0E-24 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0468 7ecc49c387340b06483c7fb578554bbc 94 Gene3D G3DSA:3.10.450.80 1 94 3.3E-28 T 23-10-2018 VMUT_0468 7ecc49c387340b06483c7fb578554bbc 94 SUPERFAMILY SSF57829 1 92 2.75E-27 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 VMUT_0468 7ecc49c387340b06483c7fb578554bbc 94 Hamap MF_01476 50S ribosomal protein L44e [rpl44e]. 1 91 22.324 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0468 7ecc49c387340b06483c7fb578554bbc 94 Pfam PF00935 Ribosomal protein L44 17 91 1.4E-26 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1642 76cd01cfde874949c1865b0499e4ccf8 610 PRINTS PR01868 ABC transporter family E signature 135 151 1.0E-54 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 VMUT_1642 76cd01cfde874949c1865b0499e4ccf8 610 PRINTS PR01868 ABC transporter family E signature 151 177 1.0E-54 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 VMUT_1642 76cd01cfde874949c1865b0499e4ccf8 610 PRINTS PR01868 ABC transporter family E signature 75 95 1.0E-54 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 VMUT_1642 76cd01cfde874949c1865b0499e4ccf8 610 PRINTS PR01868 ABC transporter family E signature 21 36 1.0E-54 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 VMUT_1642 76cd01cfde874949c1865b0499e4ccf8 610 PRINTS PR01868 ABC transporter family E signature 48 72 1.0E-54 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 VMUT_1642 76cd01cfde874949c1865b0499e4ccf8 610 PRINTS PR01868 ABC transporter family E signature 103 128 1.0E-54 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 VMUT_1642 76cd01cfde874949c1865b0499e4ccf8 610 ProSitePatterns PS00211 ABC transporters family signature. 463 477 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VMUT_1642 76cd01cfde874949c1865b0499e4ccf8 610 Pfam PF00005 ABC transporter 364 491 7.2E-17 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_1642 76cd01cfde874949c1865b0499e4ccf8 610 Gene3D G3DSA:3.40.50.300 334 598 1.0E-48 T 23-10-2018 VMUT_1642 76cd01cfde874949c1865b0499e4ccf8 610 SUPERFAMILY SSF52540 332 550 8.45E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1642 76cd01cfde874949c1865b0499e4ccf8 610 SUPERFAMILY SSF52540 96 285 5.5E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1642 76cd01cfde874949c1865b0499e4ccf8 610 Pfam PF00005 ABC transporter 98 240 8.8E-18 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_1642 76cd01cfde874949c1865b0499e4ccf8 610 Pfam PF04068 Possible Fer4-like domain in RNase L inhibitor, RLI 3 33 1.6E-12 T 23-10-2018 IPR007209 RNase L inhibitor RLI, possible metal-binding domain VMUT_1642 76cd01cfde874949c1865b0499e4ccf8 610 SUPERFAMILY SSF54862 6 124 1.06E-16 T 23-10-2018 VMUT_1642 76cd01cfde874949c1865b0499e4ccf8 610 Pfam PF00037 4Fe-4S binding domain 45 67 1.2E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_1642 76cd01cfde874949c1865b0499e4ccf8 610 Gene3D G3DSA:3.40.50.300 1 328 6.2E-75 T 23-10-2018 VMUT_1642 76cd01cfde874949c1865b0499e4ccf8 610 ProSitePatterns PS00211 ABC transporters family signature. 213 227 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VMUT_1642 76cd01cfde874949c1865b0499e4ccf8 610 SMART SM00382 98 290 1.6E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_1642 76cd01cfde874949c1865b0499e4ccf8 610 SMART SM00382 366 520 2.1E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_1642 76cd01cfde874949c1865b0499e4ccf8 610 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 51 62 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_2295 9b7f754751606f1ffeb09f57570cda07 416 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 35 409 1.1E-128 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VMUT_2295 9b7f754751606f1ffeb09f57570cda07 416 SUPERFAMILY SSF55035 132 246 6.02E-46 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VMUT_2295 9b7f754751606f1ffeb09f57570cda07 416 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 189 203 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VMUT_2295 9b7f754751606f1ffeb09f57570cda07 416 Gene3D G3DSA:3.90.770.10 78 396 6.7E-127 T 23-10-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VMUT_2295 9b7f754751606f1ffeb09f57570cda07 416 Gene3D G3DSA:1.10.3270.10 3 77 1.0E-6 T 23-10-2018 IPR023282 Hydroxymethylglutaryl-CoA reductase, N-terminal GO:0004420 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VMUT_2295 9b7f754751606f1ffeb09f57570cda07 416 SUPERFAMILY SSF56542 8 398 1.96E-84 T 23-10-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VMUT_2295 9b7f754751606f1ffeb09f57570cda07 416 Gene3D G3DSA:3.30.70.420 132 246 6.7E-127 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VMUT_2295 9b7f754751606f1ffeb09f57570cda07 416 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 341 348 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VMUT_2295 9b7f754751606f1ffeb09f57570cda07 416 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 67 88 2.6E-53 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VMUT_2295 9b7f754751606f1ffeb09f57570cda07 416 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 98 118 2.6E-53 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VMUT_2295 9b7f754751606f1ffeb09f57570cda07 416 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 227 252 2.6E-53 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VMUT_2295 9b7f754751606f1ffeb09f57570cda07 416 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 187 205 2.6E-53 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VMUT_2295 9b7f754751606f1ffeb09f57570cda07 416 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 276 302 2.6E-53 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VMUT_2295 9b7f754751606f1ffeb09f57570cda07 416 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 329 350 2.6E-53 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VMUT_2295 9b7f754751606f1ffeb09f57570cda07 416 TIGRFAM TIGR00533 HMG_CoA_R_NADP: hydroxymethylglutaryl-CoA reductase (NADPH) 9 409 3.3E-152 T 23-10-2018 IPR004554 Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type GO:0004420|GO:0008299|GO:0016021|GO:0050661|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VMUT_0349 15697b0a33af8ffaf8724a077ad0c4f1 407 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 274 379 2.4E-25 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II VMUT_0349 15697b0a33af8ffaf8724a077ad0c4f1 407 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 29 251 9.2E-72 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 VMUT_0349 15697b0a33af8ffaf8724a077ad0c4f1 407 SUPERFAMILY SSF52518 17 263 1.03E-66 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold VMUT_0349 15697b0a33af8ffaf8724a077ad0c4f1 407 Gene3D G3DSA:3.40.50.970 15 264 8.2E-96 T 23-10-2018 VMUT_0349 15697b0a33af8ffaf8724a077ad0c4f1 407 SUPERFAMILY SSF52922 265 387 1.23E-28 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VMUT_0349 15697b0a33af8ffaf8724a077ad0c4f1 407 Gene3D G3DSA:3.40.50.920 265 407 5.8E-37 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VMUT_1112 167444f2c62762ca04fb0bb44084dbd6 376 Gene3D G3DSA:3.90.550.10 32 262 1.6E-42 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1112 167444f2c62762ca04fb0bb44084dbd6 376 SUPERFAMILY SSF53448 49 319 4.98E-53 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1112 167444f2c62762ca04fb0bb44084dbd6 376 Pfam PF00535 Glycosyl transferase family 2 54 220 2.0E-34 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VMUT_2121 06b16f6b6d052998dcee6daadc45975b 366 Hamap MF_00701 DNA primase large subunit PriL [priL]. 13 360 37.662 T 23-10-2018 IPR023642 DNA primase large subunit PriL GO:0003896 VMUT_2121 06b16f6b6d052998dcee6daadc45975b 366 Pfam PF04104 Eukaryotic and archaeal DNA primase, large subunit 149 339 2.9E-27 T 23-10-2018 IPR007238 DNA primase large subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 VMUT_2121 06b16f6b6d052998dcee6daadc45975b 366 SUPERFAMILY SSF140914 12 251 1.57E-40 T 23-10-2018 VMUT_0776 6809b8083c2a06bd3f3283cb0e0ecac4 588 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 423 576 2.0E-29 T 23-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 VMUT_0776 6809b8083c2a06bd3f3283cb0e0ecac4 588 PRINTS PR00987 Glutamyl-tRNA synthetase signature 315 323 4.0E-12 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 VMUT_0776 6809b8083c2a06bd3f3283cb0e0ecac4 588 PRINTS PR00987 Glutamyl-tRNA synthetase signature 299 309 4.0E-12 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 VMUT_0776 6809b8083c2a06bd3f3283cb0e0ecac4 588 PRINTS PR00987 Glutamyl-tRNA synthetase signature 111 123 4.0E-12 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 VMUT_0776 6809b8083c2a06bd3f3283cb0e0ecac4 588 PRINTS PR00987 Glutamyl-tRNA synthetase signature 125 136 4.0E-12 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 VMUT_0776 6809b8083c2a06bd3f3283cb0e0ecac4 588 SUPERFAMILY SSF50715 423 576 7.32E-25 T 23-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 VMUT_0776 6809b8083c2a06bd3f3283cb0e0ecac4 588 Gene3D G3DSA:3.40.50.620 101 422 5.1E-94 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_0776 6809b8083c2a06bd3f3283cb0e0ecac4 588 TIGRFAM TIGR00463 gltX_arch: glutamate--tRNA ligase 10 581 6.7E-156 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 VMUT_0776 6809b8083c2a06bd3f3283cb0e0ecac4 588 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 108 417 6.0E-62 T 23-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 VMUT_0776 6809b8083c2a06bd3f3283cb0e0ecac4 588 Gene3D G3DSA:2.40.240.10 432 533 2.8E-36 T 23-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 VMUT_0776 6809b8083c2a06bd3f3283cb0e0ecac4 588 Hamap MF_02076 Glutamate--tRNA ligase [gltX]. 12 586 33.926 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 VMUT_0776 6809b8083c2a06bd3f3283cb0e0ecac4 588 SUPERFAMILY SSF52374 108 429 7.19E-72 T 23-10-2018 VMUT_0776 6809b8083c2a06bd3f3283cb0e0ecac4 588 Gene3D G3DSA:2.40.240.100 423 587 2.8E-36 T 23-10-2018 VMUT_0855 a3be7dd05ff47e2250310614219ad7d4 100 Pfam PF01929 Ribosomal protein L14 46 84 9.8E-5 T 23-10-2018 IPR002784 Ribosomal protein L14e domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0855 a3be7dd05ff47e2250310614219ad7d4 100 SUPERFAMILY SSF50104 3 88 2.62E-24 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily VMUT_0855 a3be7dd05ff47e2250310614219ad7d4 100 Gene3D G3DSA:2.30.30.30 4 88 5.7E-35 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 VMUT_0855 a3be7dd05ff47e2250310614219ad7d4 100 Hamap MF_00721 50S ribosomal protein L14e [rpl14e]. 2 81 28.014 T 23-10-2018 IPR023651 Ribosomal protein L14e GO:0003735|GO:0005840|GO:0006412 VMUT_0372 ff151331cdddc8649b90aecd3438872e 552 Gene3D G3DSA:3.30.930.10 362 550 4.0E-36 T 23-10-2018 VMUT_0372 ff151331cdddc8649b90aecd3438872e 552 SUPERFAMILY SSF55681 342 549 2.73E-33 T 23-10-2018 VMUT_0372 ff151331cdddc8649b90aecd3438872e 552 Gene3D G3DSA:3.30.56.10 275 344 7.1E-17 T 23-10-2018 VMUT_0372 ff151331cdddc8649b90aecd3438872e 552 Gene3D G3DSA:3.50.40.10 80 274 2.5E-48 T 23-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 VMUT_0372 ff151331cdddc8649b90aecd3438872e 552 SUPERFAMILY SSF56037 136 255 3.66E-5 T 23-10-2018 VMUT_0372 ff151331cdddc8649b90aecd3438872e 552 SUPERFAMILY SSF46955 4 77 5.77E-8 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily VMUT_0372 ff151331cdddc8649b90aecd3438872e 552 TIGRFAM TIGR00471 pheT_arch: phenylalanine--tRNA ligase, beta subunit 1 550 4.5E-131 T 23-10-2018 IPR004531 Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 VMUT_0372 ff151331cdddc8649b90aecd3438872e 552 SMART SM00874 276 344 9.8E-15 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 VMUT_0372 ff151331cdddc8649b90aecd3438872e 552 Gene3D G3DSA:3.30.56.10 1 76 1.0E-14 T 23-10-2018 VMUT_0372 ff151331cdddc8649b90aecd3438872e 552 Pfam PF03483 B3/4 domain 112 233 4.6E-13 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 VMUT_0372 ff151331cdddc8649b90aecd3438872e 552 Pfam PF03484 tRNA synthetase B5 domain 280 344 9.3E-12 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 VMUT_0372 ff151331cdddc8649b90aecd3438872e 552 SMART SM00873 94 253 2.3E-6 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 VMUT_0372 ff151331cdddc8649b90aecd3438872e 552 SUPERFAMILY SSF46955 277 348 2.56E-14 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily VMUT_1873 8f7e15d42055d7172414b11f691acd15 108 SMART SM00966 71 107 0.25 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VMUT_1873 8f7e15d42055d7172414b11f691acd15 108 SMART SM00966 24 67 16.0 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VMUT_1873 8f7e15d42055d7172414b11f691acd15 108 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 73 100 1.2E-7 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VMUT_1873 8f7e15d42055d7172414b11f691acd15 108 Gene3D G3DSA:2.10.260.10 20 106 2.5E-11 T 23-10-2018 VMUT_1873 8f7e15d42055d7172414b11f691acd15 108 SUPERFAMILY SSF89447 72 101 1.92E-6 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily VMUT_0951 949cef1fbaa2bb1baf4573d6113b036d 292 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 165 6.2E-37 T 23-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 VMUT_0951 949cef1fbaa2bb1baf4573d6113b036d 292 SUPERFAMILY SSF48179 166 291 2.15E-31 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VMUT_0951 949cef1fbaa2bb1baf4573d6113b036d 292 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 168 289 7.0E-26 T 23-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 VMUT_0951 949cef1fbaa2bb1baf4573d6113b036d 292 Gene3D G3DSA:3.40.50.720 2 165 1.1E-44 T 23-10-2018 VMUT_0951 949cef1fbaa2bb1baf4573d6113b036d 292 PIRSF PIRSF000103 1 292 1.3E-78 T 23-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 VMUT_0951 949cef1fbaa2bb1baf4573d6113b036d 292 SUPERFAMILY SSF51735 4 166 6.85E-40 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0951 949cef1fbaa2bb1baf4573d6113b036d 292 Gene3D G3DSA:1.10.1040.10 166 292 2.5E-32 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VMUT_1944 c7b2d05ea2a7e864682c02bc6774c769 338 Gene3D G3DSA:3.30.470.20 107 336 6.0E-78 T 23-10-2018 VMUT_1944 c7b2d05ea2a7e864682c02bc6774c769 338 Hamap MF_01163 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [purP]. 17 338 49.097 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 VMUT_1944 c7b2d05ea2a7e864682c02bc6774c769 338 Pfam PF06973 Domain of unknown function (DUF1297) 177 338 4.1E-60 T 23-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 VMUT_1944 c7b2d05ea2a7e864682c02bc6774c769 338 Gene3D G3DSA:3.40.50.20 1 105 5.2E-25 T 23-10-2018 VMUT_1944 c7b2d05ea2a7e864682c02bc6774c769 338 SUPERFAMILY SSF52440 4 117 7.0E-35 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily VMUT_1944 c7b2d05ea2a7e864682c02bc6774c769 338 Pfam PF06849 Protein of unknown function (DUF1246) 19 137 4.8E-39 T 23-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 VMUT_1944 c7b2d05ea2a7e864682c02bc6774c769 338 SUPERFAMILY SSF56059 121 338 3.37E-75 T 23-10-2018 VMUT_1944 c7b2d05ea2a7e864682c02bc6774c769 338 PIRSF PIRSF004602 1 338 1.9E-130 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 VMUT_1944 c7b2d05ea2a7e864682c02bc6774c769 338 Gene3D G3DSA:3.30.1490.20 134 187 6.0E-78 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VMUT_0111 cf252e9a5674ad6b45a79ddcf5cf3f87 212 Gene3D G3DSA:3.40.50.300 12 146 9.1E-11 T 23-10-2018 VMUT_0111 cf252e9a5674ad6b45a79ddcf5cf3f87 212 SMART SM00382 35 162 6.1E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0111 cf252e9a5674ad6b45a79ddcf5cf3f87 212 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 40 154 1.6E-4 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VMUT_0111 cf252e9a5674ad6b45a79ddcf5cf3f87 212 SUPERFAMILY SSF52540 21 168 8.15E-13 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1572 9e5a487e5248fd4ad95f5b4c10ed9af6 142 ProSitePatterns PS00194 Thioredoxin family active site. 55 73 - T 23-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 VMUT_1572 9e5a487e5248fd4ad95f5b4c10ed9af6 142 Gene3D G3DSA:3.40.30.10 32 136 1.3E-27 T 23-10-2018 VMUT_1572 9e5a487e5248fd4ad95f5b4c10ed9af6 142 PRINTS PR00421 Thioredoxin family signature 54 62 7.3E-5 T 23-10-2018 VMUT_1572 9e5a487e5248fd4ad95f5b4c10ed9af6 142 PRINTS PR00421 Thioredoxin family signature 62 71 7.3E-5 T 23-10-2018 VMUT_1572 9e5a487e5248fd4ad95f5b4c10ed9af6 142 PRINTS PR00421 Thioredoxin family signature 102 113 7.3E-5 T 23-10-2018 VMUT_1572 9e5a487e5248fd4ad95f5b4c10ed9af6 142 SUPERFAMILY SSF52833 30 138 9.49E-32 T 23-10-2018 IPR036249 Thioredoxin-like superfamily VMUT_1572 9e5a487e5248fd4ad95f5b4c10ed9af6 142 PIRSF PIRSF000077 34 138 3.0E-27 T 23-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 VMUT_1572 9e5a487e5248fd4ad95f5b4c10ed9af6 142 Pfam PF00085 Thioredoxin 37 134 2.1E-21 T 23-10-2018 IPR013766 Thioredoxin domain GO:0045454 VMUT_0213 e9d3abe909e4fcce8a97ca27e22ad0cb 254 Gene3D G3DSA:3.40.1160.10 1 249 1.1E-40 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily VMUT_0213 e9d3abe909e4fcce8a97ca27e22ad0cb 254 SUPERFAMILY SSF53633 1 244 1.07E-28 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily VMUT_0213 e9d3abe909e4fcce8a97ca27e22ad0cb 254 PIRSF PIRSF016496 1 250 3.0E-53 T 23-10-2018 IPR024192 Fosfomycin resistance kinase, FomA-type GO:0016301 KEGG: 00900+2.7.4.26|MetaCyc: PWY-6174|MetaCyc: PWY-7524 VMUT_0213 e9d3abe909e4fcce8a97ca27e22ad0cb 254 Pfam PF00696 Amino acid kinase family 3 221 6.7E-32 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 VMUT_0846 d97278e6c554e2c0f40375fb3e5d4fe9 191 SMART SM00028 38 71 0.18 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VMUT_0846 d97278e6c554e2c0f40375fb3e5d4fe9 191 SMART SM00028 81 107 50.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VMUT_0846 d97278e6c554e2c0f40375fb3e5d4fe9 191 SUPERFAMILY SSF48452 6 130 6.9E-18 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VMUT_0846 d97278e6c554e2c0f40375fb3e5d4fe9 191 Pfam PF12895 Anaphase-promoting complex, cyclosome, subunit 3 60 134 1.8E-6 T 23-10-2018 VMUT_0846 d97278e6c554e2c0f40375fb3e5d4fe9 191 Gene3D G3DSA:1.25.40.10 74 162 5.0E-9 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VMUT_0846 d97278e6c554e2c0f40375fb3e5d4fe9 191 Gene3D G3DSA:1.25.40.10 4 73 3.2E-6 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VMUT_2189 8ed33e5d2048cca26cac91a613d04b48 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 303 7.3E-19 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VMUT_2189 8ed33e5d2048cca26cac91a613d04b48 327 SUPERFAMILY SSF52540 28 261 5.45E-71 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_2189 8ed33e5d2048cca26cac91a613d04b48 327 Pfam PF00005 ABC transporter 39 190 3.7E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_2189 8ed33e5d2048cca26cac91a613d04b48 327 SMART SM00382 47 242 7.9E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_2189 8ed33e5d2048cca26cac91a613d04b48 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 239 323 2.1E-25 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VMUT_2189 8ed33e5d2048cca26cac91a613d04b48 327 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VMUT_2189 8ed33e5d2048cca26cac91a613d04b48 327 Gene3D G3DSA:3.40.50.300 24 327 8.1E-94 T 23-10-2018 VMUT_2242 cc2925788d2c54713e5b87a03bb737f9 400 Gene3D G3DSA:3.50.50.60 6 317 2.4E-61 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_2242 cc2925788d2c54713e5b87a03bb737f9 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 159 174 1.0E-13 T 23-10-2018 VMUT_2242 cc2925788d2c54713e5b87a03bb737f9 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 313 1.0E-13 T 23-10-2018 VMUT_2242 cc2925788d2c54713e5b87a03bb737f9 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.0E-13 T 23-10-2018 VMUT_2242 cc2925788d2c54713e5b87a03bb737f9 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 297 1.0E-13 T 23-10-2018 VMUT_2242 cc2925788d2c54713e5b87a03bb737f9 400 Gene3D G3DSA:3.30.9.10 78 276 2.4E-61 T 23-10-2018 VMUT_2242 cc2925788d2c54713e5b87a03bb737f9 400 SUPERFAMILY SSF51905 4 342 3.41E-31 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_2242 cc2925788d2c54713e5b87a03bb737f9 400 Pfam PF01494 FAD binding domain 4 39 1.4E-5 T 23-10-2018 IPR002938 FAD-binding domain GO:0071949 VMUT_0104 b08efbb85161eb9b94b6e21b09833d8e 478 SUPERFAMILY SSF160240 240 316 9.55E-20 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 VMUT_0104 b08efbb85161eb9b94b6e21b09833d8e 478 SUPERFAMILY SSF160240 314 392 6.41E-12 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 VMUT_0104 b08efbb85161eb9b94b6e21b09833d8e 478 Pfam PF01545 Cation efflux family 33 236 1.1E-38 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 VMUT_0104 b08efbb85161eb9b94b6e21b09833d8e 478 Gene3D G3DSA:3.30.70.1350 397 477 1.2E-5 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 VMUT_0104 b08efbb85161eb9b94b6e21b09833d8e 478 Gene3D G3DSA:1.20.1510.10 28 236 3.0E-47 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily VMUT_0104 b08efbb85161eb9b94b6e21b09833d8e 478 Gene3D G3DSA:3.30.70.1350 237 316 2.3E-19 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 VMUT_0104 b08efbb85161eb9b94b6e21b09833d8e 478 Gene3D G3DSA:3.30.70.1350 317 394 6.5E-10 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 VMUT_0104 b08efbb85161eb9b94b6e21b09833d8e 478 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 29 316 6.5E-57 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 VMUT_0104 b08efbb85161eb9b94b6e21b09833d8e 478 SUPERFAMILY SSF161111 27 237 1.11E-41 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily VMUT_0104 b08efbb85161eb9b94b6e21b09833d8e 478 Pfam PF16916 Dimerisation domain of Zinc Transporter 241 316 4.7E-21 T 23-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain VMUT_0104 b08efbb85161eb9b94b6e21b09833d8e 478 Pfam PF16916 Dimerisation domain of Zinc Transporter 318 392 9.7E-8 T 23-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain VMUT_0104 b08efbb85161eb9b94b6e21b09833d8e 478 Pfam PF16916 Dimerisation domain of Zinc Transporter 401 473 2.9E-6 T 23-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain VMUT_0104 b08efbb85161eb9b94b6e21b09833d8e 478 SUPERFAMILY SSF160240 399 473 1.96E-8 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 VMUT_0973 42bc285e1f5ac85306f858d9afe07c19 248 SUPERFAMILY SSF159659 6 236 3.27E-26 T 23-10-2018 VMUT_0973 42bc285e1f5ac85306f858d9afe07c19 248 Gene3D G3DSA:3.40.50.10900 1 244 6.8E-40 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily VMUT_0973 42bc285e1f5ac85306f858d9afe07c19 248 Pfam PF09754 PAC2 family 2 230 3.5E-33 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 VMUT_2174 dc0da05d9a5ce22b8a924f0ccef0ed00 278 Gene3D G3DSA:3.60.20.10 1 141 1.0E-7 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VMUT_1335 975b3665676c71f2b8398d11f426c9f1 413 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 106 146 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 VMUT_1335 975b3665676c71f2b8398d11f426c9f1 413 Gene3D G3DSA:3.40.630.10 3 184 8.3E-46 T 23-10-2018 VMUT_1335 975b3665676c71f2b8398d11f426c9f1 413 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 13 402 8.0E-95 T 23-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase VMUT_1335 975b3665676c71f2b8398d11f426c9f1 413 SUPERFAMILY SSF53187 5 411 2.2E-64 T 23-10-2018 VMUT_1335 975b3665676c71f2b8398d11f426c9f1 413 SUPERFAMILY SSF55031 181 317 8.67E-17 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VMUT_1335 975b3665676c71f2b8398d11f426c9f1 413 Pfam PF01546 Peptidase family M20/M25/M40 71 408 1.2E-36 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 VMUT_1335 975b3665676c71f2b8398d11f426c9f1 413 Gene3D G3DSA:3.40.630.10 317 413 9.2E-14 T 23-10-2018 VMUT_1335 975b3665676c71f2b8398d11f426c9f1 413 Pfam PF07687 Peptidase dimerisation domain 178 314 3.3E-21 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain VMUT_2328 e91c96073f0c8ca6bc267a712fa4f287 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 217 4.4E-23 T 23-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VMUT_2328 e91c96073f0c8ca6bc267a712fa4f287 387 SUPERFAMILY SSF47203 228 381 5.96E-52 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VMUT_2328 e91c96073f0c8ca6bc267a712fa4f287 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 376 1.1E-46 T 23-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VMUT_2328 e91c96073f0c8ca6bc267a712fa4f287 387 PIRSF PIRSF016578 7 386 1.9E-21 T 23-10-2018 VMUT_2328 e91c96073f0c8ca6bc267a712fa4f287 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 119 1.1E-27 T 23-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VMUT_2328 e91c96073f0c8ca6bc267a712fa4f287 387 Gene3D G3DSA:1.20.140.10 234 381 3.5E-47 T 23-10-2018 VMUT_2328 e91c96073f0c8ca6bc267a712fa4f287 387 SUPERFAMILY SSF56645 3 240 7.59E-71 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VMUT_2328 e91c96073f0c8ca6bc267a712fa4f287 387 Gene3D G3DSA:2.40.110.10 122 233 6.8E-36 T 23-10-2018 VMUT_2328 e91c96073f0c8ca6bc267a712fa4f287 387 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 23-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 VMUT_2328 e91c96073f0c8ca6bc267a712fa4f287 387 Gene3D G3DSA:1.10.540.10 2 121 2.7E-32 T 23-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VMUT_0857 faa4bb4f722ea30b43220b7b6ebada5a 243 PIRSF PIRSF001357 2 243 6.0E-59 T 23-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 VMUT_0857 faa4bb4f722ea30b43220b7b6ebada5a 243 Pfam PF01791 DeoC/LacD family aldolase 21 215 9.1E-7 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 VMUT_0857 faa4bb4f722ea30b43220b7b6ebada5a 243 SMART SM01133 4 238 3.0E-47 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 VMUT_0857 faa4bb4f722ea30b43220b7b6ebada5a 243 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 3 240 26.735 T 23-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 VMUT_0857 faa4bb4f722ea30b43220b7b6ebada5a 243 Gene3D G3DSA:3.20.20.70 5 236 1.8E-65 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_0857 faa4bb4f722ea30b43220b7b6ebada5a 243 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 7 217 4.7E-42 T 23-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 VMUT_0857 faa4bb4f722ea30b43220b7b6ebada5a 243 SUPERFAMILY SSF51569 4 239 7.22E-53 T 23-10-2018 VMUT_1398 79c92b538b6be2c88ae74554ba64b764 190 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 4 190 5.4E-34 T 23-10-2018 IPR013343 CRISPR-associated protein Cas4 VMUT_1398 79c92b538b6be2c88ae74554ba64b764 190 Gene3D G3DSA:3.90.320.10 6 190 9.6E-12 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal VMUT_1398 79c92b538b6be2c88ae74554ba64b764 190 Pfam PF01930 Domain of unknown function DUF83 6 188 7.8E-16 T 23-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 VMUT_1272 3274ad9c0ef5fcde126a93d140031129 228 TIGRFAM TIGR01008 uS3_euk_arch: ribosomal protein uS3 11 202 6.9E-62 T 23-10-2018 IPR005703 Ribosomal protein S3, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1272 3274ad9c0ef5fcde126a93d140031129 228 SUPERFAMILY SSF54821 94 191 9.94E-23 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1272 3274ad9c0ef5fcde126a93d140031129 228 SMART SM00322 45 111 3.7E-4 T 23-10-2018 IPR004087 K Homology domain GO:0003676 VMUT_1272 3274ad9c0ef5fcde126a93d140031129 228 SUPERFAMILY SSF54814 17 102 1.15E-17 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 VMUT_1272 3274ad9c0ef5fcde126a93d140031129 228 Pfam PF00189 Ribosomal protein S3, C-terminal domain 106 189 9.8E-20 T 23-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1272 3274ad9c0ef5fcde126a93d140031129 228 Gene3D G3DSA:3.30.1140.32 95 228 8.5E-28 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1272 3274ad9c0ef5fcde126a93d140031129 228 Gene3D G3DSA:3.30.300.20 1 92 2.2E-21 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta VMUT_1272 3274ad9c0ef5fcde126a93d140031129 228 Hamap MF_01309_A 30S ribosomal protein S3 [rpsC]. 9 203 36.15 T 23-10-2018 IPR027488 Ribosomal protein S3, archaeal GO:0003735|GO:0006412|GO:0015935 VMUT_1272 3274ad9c0ef5fcde126a93d140031129 228 Pfam PF07650 KH domain 24 88 1.5E-7 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_2158 82b45c2e8033144a736e3b208099521c 252 Pfam PF00239 Resolvase, N terminal domain 4 157 3.3E-32 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 VMUT_2158 82b45c2e8033144a736e3b208099521c 252 Gene3D G3DSA:1.10.10.60 163 203 4.7E-6 T 23-10-2018 VMUT_2158 82b45c2e8033144a736e3b208099521c 252 Pfam PF13384 Homeodomain-like domain 172 204 1.4E-5 T 23-10-2018 VMUT_2158 82b45c2e8033144a736e3b208099521c 252 Gene3D G3DSA:3.40.50.1390 2 162 4.1E-30 T 23-10-2018 VMUT_2158 82b45c2e8033144a736e3b208099521c 252 SMART SM00857 4 158 5.4E-40 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 VMUT_2158 82b45c2e8033144a736e3b208099521c 252 SUPERFAMILY SSF53041 4 158 7.85E-28 T 23-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 VMUT_2158 82b45c2e8033144a736e3b208099521c 252 ProSitePatterns PS00397 Site-specific recombinases active site. 7 15 - T 23-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 VMUT_1304 8e3af5e4636e49a4e23cfe8839dc8352 126 SMART SM00960 13 100 1.6E-11 T 23-10-2018 IPR004942 Roadblock/LAMTOR2 domain VMUT_1304 8e3af5e4636e49a4e23cfe8839dc8352 126 SUPERFAMILY SSF103196 11 124 5.1E-18 T 23-10-2018 VMUT_1304 8e3af5e4636e49a4e23cfe8839dc8352 126 Gene3D G3DSA:3.30.450.30 1 126 4.7E-20 T 23-10-2018 VMUT_1304 8e3af5e4636e49a4e23cfe8839dc8352 126 SMART SM01278 11 124 8.2E-4 T 23-10-2018 IPR015019 Ragulator complex protein LAMTOR3 GO:0032006 Reactome: R-HSA-1632852|Reactome: R-HSA-165159|Reactome: R-HSA-166208|Reactome: R-HSA-380972|Reactome: R-HSA-5628897|Reactome: R-HSA-5674135|Reactome: R-HSA-6798695|Reactome: R-HSA-8943724 VMUT_1304 8e3af5e4636e49a4e23cfe8839dc8352 126 Pfam PF03259 Roadblock/LC7 domain 22 100 1.1E-6 T 23-10-2018 IPR004942 Roadblock/LAMTOR2 domain VMUT_1679 d76628d97274e8c917d8276612e029cf 283 Hamap MF_00622 Exosome complex component Rrp42 [rrp42]. 7 273 40.44 T 23-10-2018 IPR020869 Exosome complex component Rrp42, archaea GO:0000178|GO:0006401 VMUT_1679 d76628d97274e8c917d8276612e029cf 283 SUPERFAMILY SSF54211 13 222 3.19E-54 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VMUT_1679 d76628d97274e8c917d8276612e029cf 283 SUPERFAMILY SSF55666 194 274 9.67E-12 T 23-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 VMUT_1679 d76628d97274e8c917d8276612e029cf 283 Gene3D G3DSA:3.30.230.70 14 277 4.0E-74 T 23-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 VMUT_1679 d76628d97274e8c917d8276612e029cf 283 Pfam PF01138 3' exoribonuclease family, domain 1 37 171 3.7E-32 T 23-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 VMUT_1679 d76628d97274e8c917d8276612e029cf 283 Pfam PF03725 3' exoribonuclease family, domain 2 199 256 1.2E-5 T 23-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 VMUT_0976 1e36c883720d4e0372efae2bd93a14a5 173 SUPERFAMILY SSF51161 4 168 3.01E-52 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily VMUT_0976 1e36c883720d4e0372efae2bd93a14a5 173 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 12 45 6.3E-9 T 23-10-2018 IPR001451 Hexapeptide repeat VMUT_0976 1e36c883720d4e0372efae2bd93a14a5 173 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 89 122 6.2E-7 T 23-10-2018 IPR001451 Hexapeptide repeat VMUT_0976 1e36c883720d4e0372efae2bd93a14a5 173 Gene3D G3DSA:2.160.10.10 1 171 6.2E-64 T 23-10-2018 VMUT_0377 b9ce201a81010da5dcad56999bc5f492 160 SUPERFAMILY SSF50249 18 139 3.43E-32 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold VMUT_0377 b9ce201a81010da5dcad56999bc5f492 160 Gene3D G3DSA:1.10.12.20 5 80 1.1E-13 T 23-10-2018 VMUT_0377 b9ce201a81010da5dcad56999bc5f492 160 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 40 76 2.1E-16 T 23-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal VMUT_0377 b9ce201a81010da5dcad56999bc5f492 160 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 77 136 3.9E-12 T 23-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal VMUT_0162 add0cccd64f8f8348e2d001a6a28ef14 470 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 366 382 - T 23-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VMUT_0162 add0cccd64f8f8348e2d001a6a28ef14 470 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 92 231 8.9E-17 T 23-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VMUT_0162 add0cccd64f8f8348e2d001a6a28ef14 470 Gene3D G3DSA:3.90.480.10 37 299 5.1E-35 T 23-10-2018 VMUT_0162 add0cccd64f8f8348e2d001a6a28ef14 470 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 21 83 8.9E-5 T 23-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VMUT_0162 add0cccd64f8f8348e2d001a6a28ef14 470 SUPERFAMILY SSF55124 3 91 8.5E-11 T 23-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VMUT_0162 add0cccd64f8f8348e2d001a6a28ef14 470 SUPERFAMILY SSF55124 216 336 1.52E-7 T 23-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VMUT_0162 add0cccd64f8f8348e2d001a6a28ef14 470 SUPERFAMILY SSF56014 326 452 1.57E-18 T 23-10-2018 VMUT_0162 add0cccd64f8f8348e2d001a6a28ef14 470 SUPERFAMILY SSF56014 92 236 1.7E-27 T 23-10-2018 VMUT_0162 add0cccd64f8f8348e2d001a6a28ef14 470 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 327 398 3.9E-5 T 23-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VMUT_0162 add0cccd64f8f8348e2d001a6a28ef14 470 Gene3D G3DSA:3.30.413.10 91 246 5.1E-35 T 23-10-2018 VMUT_0162 add0cccd64f8f8348e2d001a6a28ef14 470 Gene3D G3DSA:3.30.413.10 325 467 2.4E-18 T 23-10-2018 VMUT_1254 f416301b4abb0c7d4f1ae2c6b316c552 283 Gene3D G3DSA:1.10.1040.10 152 281 2.0E-40 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VMUT_1254 f416301b4abb0c7d4f1ae2c6b316c552 283 SUPERFAMILY SSF48179 152 275 1.7E-38 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VMUT_1254 f416301b4abb0c7d4f1ae2c6b316c552 283 PIRSF PIRSF000103 1 283 2.1E-80 T 23-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 VMUT_1254 f416301b4abb0c7d4f1ae2c6b316c552 283 SUPERFAMILY SSF51735 1 153 1.05E-45 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1254 f416301b4abb0c7d4f1ae2c6b316c552 283 Gene3D G3DSA:3.40.50.720 1 151 1.0E-51 T 23-10-2018 VMUT_1254 f416301b4abb0c7d4f1ae2c6b316c552 283 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 1 151 1.9E-46 T 23-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 VMUT_1254 f416301b4abb0c7d4f1ae2c6b316c552 283 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 154 274 4.6E-35 T 23-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 VMUT_0511 303d329b7f64f190bd39ddab873b51c1 356 Pfam PF01992 ATP synthase (C/AC39) subunit 15 347 6.3E-33 T 23-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 VMUT_0511 303d329b7f64f190bd39ddab873b51c1 356 SUPERFAMILY SSF103486 13 348 5.49E-32 T 23-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 VMUT_0511 303d329b7f64f190bd39ddab873b51c1 356 Gene3D G3DSA:1.10.132.50 11 125 1.7E-5 T 23-10-2018 VMUT_2202 1f6c1613e089bbf51681717739a30f09 302 Gene3D G3DSA:3.40.50.300 7 264 2.3E-74 T 23-10-2018 VMUT_2202 1f6c1613e089bbf51681717739a30f09 302 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 19 266 1.2E-87 T 23-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 VMUT_2202 1f6c1613e089bbf51681717739a30f09 302 Hamap MF_02040 Iron-sulfur cluster carrier protein. 14 267 33.181 T 23-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein VMUT_2202 1f6c1613e089bbf51681717739a30f09 302 SUPERFAMILY SSF52540 22 271 1.9E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0542 eba35bcacee58278938a8d14bb01ed8c 104 Gene3D G3DSA:1.10.1060.10 2 104 8.0E-10 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VMUT_0542 eba35bcacee58278938a8d14bb01ed8c 104 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 71 82 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_0542 eba35bcacee58278938a8d14bb01ed8c 104 Pfam PF13183 4Fe-4S dicluster domain 11 85 1.8E-10 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_0542 eba35bcacee58278938a8d14bb01ed8c 104 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 14 25 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_0542 eba35bcacee58278938a8d14bb01ed8c 104 SUPERFAMILY SSF46548 8 99 4.53E-17 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VMUT_0319 9c8346d79155e62fb7b19ab51034c2eb 536 SMART SM00387 29 148 8.2E-4 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VMUT_0319 9c8346d79155e62fb7b19ab51034c2eb 536 SUPERFAMILY SSF46946 234 304 9.03E-6 T 23-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 VMUT_0319 9c8346d79155e62fb7b19ab51034c2eb 536 Gene3D G3DSA:3.30.565.10 3 231 4.6E-71 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VMUT_0319 9c8346d79155e62fb7b19ab51034c2eb 536 PIRSF PIRSF006553 2 535 4.8E-183 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 VMUT_0319 9c8346d79155e62fb7b19ab51034c2eb 536 TIGRFAM TIGR01052 top6b: DNA topoisomerase VI, B subunit 8 488 3.3E-142 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 VMUT_0319 9c8346d79155e62fb7b19ab51034c2eb 536 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 127 1.3E-11 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VMUT_0319 9c8346d79155e62fb7b19ab51034c2eb 536 SUPERFAMILY SSF55874 16 213 1.31E-34 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VMUT_0319 9c8346d79155e62fb7b19ab51034c2eb 536 Gene3D G3DSA:3.30.230.10 310 527 3.0E-70 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup VMUT_0319 9c8346d79155e62fb7b19ab51034c2eb 536 ProDom PD013790 TOPOISOMERASE ISOMERASE SUBUNIT DNA B VI TYPE II NUCLEOTIDE-BINDING ATP-BINDING 309 508 3.0E-69 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 VMUT_0319 9c8346d79155e62fb7b19ab51034c2eb 536 Pfam PF09239 Topoisomerase VI B subunit, transducer 311 465 9.9E-62 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 VMUT_0319 9c8346d79155e62fb7b19ab51034c2eb 536 SUPERFAMILY SSF54211 310 469 2.12E-56 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VMUT_0319 9c8346d79155e62fb7b19ab51034c2eb 536 Hamap MF_00322 Type 2 DNA topoisomerase 6 subunit B [top6B]. 6 506 27.371 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 VMUT_0319 9c8346d79155e62fb7b19ab51034c2eb 536 Gene3D G3DSA:1.10.8.50 233 309 1.8E-21 T 23-10-2018 VMUT_1819 1815d5e7eab5a7a248f9100c34cfa1c7 127 Gene3D G3DSA:3.30.1330.40 1 127 1.0E-53 T 23-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VMUT_1819 1815d5e7eab5a7a248f9100c34cfa1c7 127 Pfam PF01042 Endoribonuclease L-PSP 9 125 2.1E-40 T 23-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 VMUT_1819 1815d5e7eab5a7a248f9100c34cfa1c7 127 SUPERFAMILY SSF55298 1 126 2.04E-45 T 23-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VMUT_1819 1815d5e7eab5a7a248f9100c34cfa1c7 127 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 4 126 7.6E-49 T 23-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 VMUT_0411 3768adefd099d2072a49739ce149a7eb 470 Gene3D G3DSA:3.40.190.10 189 449 2.9E-55 T 23-10-2018 VMUT_0411 3768adefd099d2072a49739ce149a7eb 470 Gene3D G3DSA:3.40.190.10 84 424 2.9E-55 T 23-10-2018 VMUT_0411 3768adefd099d2072a49739ce149a7eb 470 Pfam PF13416 Bacterial extracellular solute-binding protein 103 394 1.0E-20 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein VMUT_0411 3768adefd099d2072a49739ce149a7eb 470 SUPERFAMILY SSF53850 72 459 3.74E-58 T 23-10-2018 VMUT_0299 ddfb726cb6b046bb87fc649687b912d8 116 Gene3D G3DSA:2.40.50.140 1 114 2.1E-10 T 23-10-2018 VMUT_2089 2be6786afd35874e42a2f9948cca29c3 240 Pfam PF13614 AAA domain 8 171 6.1E-10 T 23-10-2018 IPR025669 AAA domain VMUT_2089 2be6786afd35874e42a2f9948cca29c3 240 Gene3D G3DSA:3.40.50.300 5 214 1.2E-21 T 23-10-2018 VMUT_2089 2be6786afd35874e42a2f9948cca29c3 240 SUPERFAMILY SSF52540 8 218 2.01E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1154 5022600d6330329aaed479c97b037ecd 439 SUPERFAMILY SSF103473 13 433 3.53E-43 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_1154 5022600d6330329aaed479c97b037ecd 439 Gene3D G3DSA:1.20.1250.20 13 437 1.2E-45 T 23-10-2018 VMUT_1154 5022600d6330329aaed479c97b037ecd 439 Pfam PF07690 Major Facilitator Superfamily 58 382 4.2E-14 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_1913 ba2135e1c55f9e65bbc6aa71bffd66aa 192 SUPERFAMILY SSF53448 1 179 1.67E-33 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1913 ba2135e1c55f9e65bbc6aa71bffd66aa 192 Gene3D G3DSA:3.90.550.10 2 176 1.6E-54 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1913 ba2135e1c55f9e65bbc6aa71bffd66aa 192 Pfam PF12804 MobA-like NTP transferase domain 5 157 7.7E-39 T 23-10-2018 IPR025877 MobA-like NTP transferase VMUT_1776 cee521023d99d5074a5da56bdf388ed8 509 PIRSF PIRSF006060 1 499 7.1E-32 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_1776 cee521023d99d5074a5da56bdf388ed8 509 Gene3D G3DSA:1.20.1740.10 17 502 1.9E-11 T 23-10-2018 VMUT_1776 cee521023d99d5074a5da56bdf388ed8 509 Pfam PF13520 Amino acid permease 33 469 6.5E-16 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_1575 e99b00361f614303e13b9b8505167cce 88 Hamap MF_00349 50S ribosomal protein L34e [rpl34e]. 2 85 21.804 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1575 e99b00361f614303e13b9b8505167cce 88 Pfam PF01199 Ribosomal protein L34e 3 76 1.5E-17 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1575 e99b00361f614303e13b9b8505167cce 88 Gene3D G3DSA:3.40.1800.40 32 82 1.3E-8 T 23-10-2018 IPR038562 Ribosomal protein L34Ae superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1575 e99b00361f614303e13b9b8505167cce 88 PRINTS PR01250 Ribosomal protein L34 signature 37 47 7.7E-15 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1575 e99b00361f614303e13b9b8505167cce 88 PRINTS PR01250 Ribosomal protein L34 signature 6 19 7.7E-15 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1575 e99b00361f614303e13b9b8505167cce 88 PRINTS PR01250 Ribosomal protein L34 signature 19 36 7.7E-15 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1575 e99b00361f614303e13b9b8505167cce 88 PRINTS PR01250 Ribosomal protein L34 signature 54 76 7.7E-15 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0741 4cc2eb251cc70fc907c610a425fde2cb 399 Pfam PF07690 Major Facilitator Superfamily 16 180 4.5E-9 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_0741 4cc2eb251cc70fc907c610a425fde2cb 399 Pfam PF07690 Major Facilitator Superfamily 220 387 3.7E-16 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_0741 4cc2eb251cc70fc907c610a425fde2cb 399 SUPERFAMILY SSF103473 8 391 4.71E-36 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_0741 4cc2eb251cc70fc907c610a425fde2cb 399 Gene3D G3DSA:1.20.1250.20 10 185 1.9E-11 T 23-10-2018 VMUT_0741 4cc2eb251cc70fc907c610a425fde2cb 399 Gene3D G3DSA:1.20.1250.20 217 390 5.6E-20 T 23-10-2018 VMUT_1778 d8d081424f92b1a76d0812451d58e47f 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 71 262 2.4E-17 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VMUT_1778 d8d081424f92b1a76d0812451d58e47f 270 SUPERFAMILY SSF161098 10 260 1.96E-36 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_1778 d8d081424f92b1a76d0812451d58e47f 270 Gene3D G3DSA:1.10.3720.10 8 265 3.2E-49 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_0858 faab894def3d52e16debdf558a151359 165 Gene3D G3DSA:3.30.420.80 8 165 1.1E-57 T 23-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 VMUT_0858 faab894def3d52e16debdf558a151359 165 ProSitePatterns PS00054 Ribosomal protein S11 signature. 130 152 - T 23-10-2018 IPR018102 Ribosomal S11, conserved site VMUT_0858 faab894def3d52e16debdf558a151359 165 PIRSF PIRSF002131 1 164 1.7E-32 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 VMUT_0858 faab894def3d52e16debdf558a151359 165 TIGRFAM TIGR03628 arch_S11P: ribosomal protein uS11 41 157 3.2E-60 T 23-10-2018 IPR019961 Ribosomal protein S11, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_0858 faab894def3d52e16debdf558a151359 165 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 8 162 21.826 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 VMUT_0858 faab894def3d52e16debdf558a151359 165 SUPERFAMILY SSF53137 39 163 1.37E-35 T 23-10-2018 VMUT_0858 faab894def3d52e16debdf558a151359 165 Pfam PF00411 Ribosomal protein S11 43 161 5.6E-44 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 VMUT_1216 e932e2df12da163b09aa714ed5c8da7c 115 Pfam PF03874 RNA polymerase Rpb4 23 111 8.6E-16 T 23-10-2018 IPR005574 RNA polymerase subunit RPB4/RPC9 GO:0006352|GO:0030880 VMUT_1216 e932e2df12da163b09aa714ed5c8da7c 115 SMART SM00657 3 113 3.1E-4 T 23-10-2018 IPR006590 RNA polymerase Rpb4/RPC9, core VMUT_1216 e932e2df12da163b09aa714ed5c8da7c 115 SUPERFAMILY SSF47819 3 112 1.0E-25 T 23-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 VMUT_1216 e932e2df12da163b09aa714ed5c8da7c 115 Gene3D G3DSA:1.20.1250.40 3 115 4.4E-16 T 23-10-2018 IPR038324 Rpb4/RPC9 superfamily VMUT_1216 e932e2df12da163b09aa714ed5c8da7c 115 PIRSF PIRSF005053 1 114 1.4E-24 T 23-10-2018 IPR010924 DNA-directed RNA polymerase subunit F (Rpo4) VMUT_1293 8a82d64db48b7cf3c07a79208046d3e1 154 Pfam PF01161 Phosphatidylethanolamine-binding protein 16 152 9.9E-40 T 23-10-2018 IPR008914 Phosphatidylethanolamine-binding protein VMUT_1293 8a82d64db48b7cf3c07a79208046d3e1 154 Gene3D G3DSA:3.90.280.10 1 154 6.2E-58 T 23-10-2018 IPR036610 PEBP-like superfamily VMUT_1293 8a82d64db48b7cf3c07a79208046d3e1 154 SUPERFAMILY SSF49777 3 153 9.68E-49 T 23-10-2018 IPR036610 PEBP-like superfamily VMUT_1293 8a82d64db48b7cf3c07a79208046d3e1 154 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 19 150 3.7E-44 T 23-10-2018 IPR005247 YbhB/YbcL VMUT_1599 300780f420440feb27466157151adfbd 218 Pfam PF13241 Putative NAD(P)-binding 5 118 5.2E-24 T 23-10-2018 VMUT_1599 300780f420440feb27466157151adfbd 218 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 3 211 9.3E-24 T 23-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 VMUT_1599 300780f420440feb27466157151adfbd 218 SUPERFAMILY SSF51735 3 111 3.52E-22 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1599 300780f420440feb27466157151adfbd 218 Gene3D G3DSA:3.40.50.720 3 134 3.2E-28 T 23-10-2018 VMUT_1599 300780f420440feb27466157151adfbd 218 SUPERFAMILY SSF75615 123 204 5.62E-7 T 23-10-2018 VMUT_1418 892a1684ae0f12594e1441de45334c89 421 SUPERFAMILY SSF56322 21 417 1.09E-120 T 23-10-2018 IPR005801 ADC synthase GO:0009058 VMUT_1418 892a1684ae0f12594e1441de45334c89 421 Gene3D G3DSA:3.60.120.10 6 421 4.1E-122 T 23-10-2018 IPR005801 ADC synthase GO:0009058 VMUT_1418 892a1684ae0f12594e1441de45334c89 421 PRINTS PR00095 Anthranilate synthase component I signature 353 367 9.2E-14 T 23-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 VMUT_1418 892a1684ae0f12594e1441de45334c89 421 PRINTS PR00095 Anthranilate synthase component I signature 367 381 9.2E-14 T 23-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 VMUT_1418 892a1684ae0f12594e1441de45334c89 421 PRINTS PR00095 Anthranilate synthase component I signature 273 286 9.2E-14 T 23-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 VMUT_1418 892a1684ae0f12594e1441de45334c89 421 PRINTS PR00095 Anthranilate synthase component I signature 259 272 9.2E-14 T 23-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 VMUT_1418 892a1684ae0f12594e1441de45334c89 421 Pfam PF00425 chorismate binding enzyme 158 410 6.0E-88 T 23-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal VMUT_0780 4e1f9b2b5c5c0e0b5bd0375ec52a9613 233 Gene3D G3DSA:3.40.50.1360 9 227 1.9E-71 T 23-10-2018 VMUT_0780 4e1f9b2b5c5c0e0b5bd0375ec52a9613 233 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 4 232 29.747 T 23-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 VMUT_0780 4e1f9b2b5c5c0e0b5bd0375ec52a9613 233 Gene3D G3DSA:3.30.70.260 132 210 1.9E-71 T 23-10-2018 VMUT_0780 4e1f9b2b5c5c0e0b5bd0375ec52a9613 233 SUPERFAMILY SSF75445 136 212 5.23E-24 T 23-10-2018 VMUT_0780 4e1f9b2b5c5c0e0b5bd0375ec52a9613 233 SUPERFAMILY SSF100950 7 184 7.09E-38 T 23-10-2018 IPR037171 NagB/RpiA transferase-like VMUT_0780 4e1f9b2b5c5c0e0b5bd0375ec52a9613 233 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 8 228 1.2E-64 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 VMUT_0780 4e1f9b2b5c5c0e0b5bd0375ec52a9613 233 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 54 227 1.4E-57 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 VMUT_2102 d22313d6f4b8fbadadc6455d93ed8834 137 Pfam PF09895 RecB-family nuclease (DUF2122) 33 129 8.3E-29 T 23-10-2018 IPR018665 Protein of unknown function DUF2122, RecB-family nuclease-related VMUT_1150 6147f07ae318f89b3f137575b252230e 380 Pfam PF13378 Enolase C-terminal domain-like 155 363 3.5E-42 T 23-10-2018 IPR029065 Enolase C-terminal domain-like VMUT_1150 6147f07ae318f89b3f137575b252230e 380 Gene3D G3DSA:3.30.390.10 3 127 3.1E-17 T 23-10-2018 IPR029017 Enolase-like, N-terminal VMUT_1150 6147f07ae318f89b3f137575b252230e 380 SUPERFAMILY SSF51604 117 371 1.1E-50 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VMUT_1150 6147f07ae318f89b3f137575b252230e 380 Gene3D G3DSA:3.20.20.120 128 376 6.2E-54 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VMUT_1150 6147f07ae318f89b3f137575b252230e 380 SMART SM00922 148 244 4.8E-17 T 23-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal VMUT_1150 6147f07ae318f89b3f137575b252230e 380 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 20 129 5.0E-11 T 23-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain VMUT_1150 6147f07ae318f89b3f137575b252230e 380 SUPERFAMILY SSF54826 4 134 2.57E-20 T 23-10-2018 VMUT_1201 f82ad816906add3cd92d141f103458be 469 Pfam PF01565 FAD binding domain 42 186 5.4E-38 T 23-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 VMUT_1201 f82ad816906add3cd92d141f103458be 469 SUPERFAMILY SSF55103 228 468 3.27E-67 T 23-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 VMUT_1201 f82ad816906add3cd92d141f103458be 469 Gene3D G3DSA:3.30.70.2740 345 426 5.0E-9 T 23-10-2018 VMUT_1201 f82ad816906add3cd92d141f103458be 469 Gene3D G3DSA:1.10.45.10 427 467 1.7E-10 T 23-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 VMUT_1201 f82ad816906add3cd92d141f103458be 469 Pfam PF02913 FAD linked oxidases, C-terminal domain 226 466 1.1E-63 T 23-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 VMUT_1201 f82ad816906add3cd92d141f103458be 469 SUPERFAMILY SSF56176 5 222 6.54E-67 T 23-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VMUT_1201 f82ad816906add3cd92d141f103458be 469 Gene3D G3DSA:3.30.465.40 4 242 6.1E-66 T 23-10-2018 VMUT_1775 8e73404ea5b9112af02c671997beb467 189 Gene3D G3DSA:2.40.320.10 3 188 1.7E-50 T 23-10-2018 VMUT_1775 8e73404ea5b9112af02c671997beb467 189 Pfam PF01928 CYTH domain 9 172 5.9E-37 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 VMUT_1775 8e73404ea5b9112af02c671997beb467 189 SUPERFAMILY SSF55154 8 179 1.05E-42 T 23-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 VMUT_1775 8e73404ea5b9112af02c671997beb467 189 SMART SM01118 7 182 8.0E-22 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 VMUT_1775 8e73404ea5b9112af02c671997beb467 189 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 8 180 3.1E-52 T 23-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 VMUT_1775 8e73404ea5b9112af02c671997beb467 189 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 7 157 5.0E-27 T 23-10-2018 VMUT_0699 e34d886246c4a025457706d7275456d2 330 Pfam PF01916 Deoxyhypusine synthase 23 313 6.3E-99 T 23-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 VMUT_0699 e34d886246c4a025457706d7275456d2 330 Hamap MF_00153 Probable deoxyhypusine synthase [dys]. 21 317 41.723 T 23-10-2018 IPR022899 Deoxyhypusine synthase, putative, archaeal GO:0034038 VMUT_0699 e34d886246c4a025457706d7275456d2 330 Gene3D G3DSA:3.40.910.10 8 324 6.3E-91 T 23-10-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 VMUT_0699 e34d886246c4a025457706d7275456d2 330 SUPERFAMILY SSF52467 4 321 3.6E-96 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily VMUT_1484 7e25fa1ded72e3ff967d929de32cead5 281 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 141 268 3.0E-13 T 23-10-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal VMUT_1484 7e25fa1ded72e3ff967d929de32cead5 281 Gene3D G3DSA:3.30.70.1900 128 278 1.3E-24 T 23-10-2018 VMUT_1484 7e25fa1ded72e3ff967d929de32cead5 281 Gene3D G3DSA:3.30.70.1890 13 126 1.7E-8 T 23-10-2018 VMUT_0011 f5b84c3a8dc01a27704f83966ac7ec47 377 Gene3D G3DSA:1.20.1250.20 1 180 2.7E-24 T 23-10-2018 VMUT_0011 f5b84c3a8dc01a27704f83966ac7ec47 377 Gene3D G3DSA:1.20.1250.20 188 376 7.6E-19 T 23-10-2018 VMUT_0011 f5b84c3a8dc01a27704f83966ac7ec47 377 Pfam PF07690 Major Facilitator Superfamily 13 340 2.3E-35 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_0011 f5b84c3a8dc01a27704f83966ac7ec47 377 SUPERFAMILY SSF103473 4 373 7.32E-52 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_0229 2e82dcac1ba50bc629897d5174aca4ac 237 Gene3D G3DSA:3.40.1080.10 1 236 2.7E-51 T 23-10-2018 VMUT_0229 2e82dcac1ba50bc629897d5174aca4ac 237 SUPERFAMILY SSF100950 2 235 1.47E-47 T 23-10-2018 IPR037171 NagB/RpiA transferase-like VMUT_0229 2e82dcac1ba50bc629897d5174aca4ac 237 SMART SM00882 2 201 1.3E-4 T 23-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 VMUT_0229 2e82dcac1ba50bc629897d5174aca4ac 237 Pfam PF01144 Coenzyme A transferase 3 200 4.3E-15 T 23-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 VMUT_2035 c83125bd3302310bfb551e5ea080163d 289 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 129 160 - T 23-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 VMUT_2035 c83125bd3302310bfb551e5ea080163d 289 SMART SM01130 1 284 1.2E-73 T 23-10-2018 IPR002220 DapA-like GO:0016829 VMUT_2035 c83125bd3302310bfb551e5ea080163d 289 Gene3D G3DSA:3.20.20.70 3 284 9.3E-79 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_2035 c83125bd3302310bfb551e5ea080163d 289 Pfam PF00701 Dihydrodipicolinate synthetase family 2 276 2.9E-47 T 23-10-2018 IPR002220 DapA-like GO:0016829 VMUT_2035 c83125bd3302310bfb551e5ea080163d 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 33 54 7.9E-14 T 23-10-2018 IPR002220 DapA-like GO:0016829 VMUT_2035 c83125bd3302310bfb551e5ea080163d 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 99 115 7.9E-14 T 23-10-2018 IPR002220 DapA-like GO:0016829 VMUT_2035 c83125bd3302310bfb551e5ea080163d 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 124 141 7.9E-14 T 23-10-2018 IPR002220 DapA-like GO:0016829 VMUT_2035 c83125bd3302310bfb551e5ea080163d 289 PIRSF PIRSF001365 1 288 2.9E-66 T 23-10-2018 IPR002220 DapA-like GO:0016829 VMUT_2035 c83125bd3302310bfb551e5ea080163d 289 SUPERFAMILY SSF51569 2 284 4.5E-71 T 23-10-2018 VMUT_1199 817f2f51ec31a3e6a260939245701212 322 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 40 211 2.0E-15 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 VMUT_1199 817f2f51ec31a3e6a260939245701212 322 SUPERFAMILY SSF52518 5 301 2.16E-63 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold VMUT_1199 817f2f51ec31a3e6a260939245701212 322 Gene3D G3DSA:3.40.50.970 70 302 6.3E-50 T 23-10-2018 VMUT_0277 07c6802214b1f77bb139b7f55c2350ba 207 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 73 95 - T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 VMUT_0277 07c6802214b1f77bb139b7f55c2350ba 207 Gene3D G3DSA:1.20.120.1760 15 205 7.5E-45 T 23-10-2018 VMUT_0277 07c6802214b1f77bb139b7f55c2350ba 207 Pfam PF01066 CDP-alcohol phosphatidyltransferase 30 95 3.2E-12 T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 VMUT_2323 c4ed0e911a8efc5a57db175ba6181b8f 339 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 4 335 3.0E-79 T 23-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 VMUT_2323 c4ed0e911a8efc5a57db175ba6181b8f 339 Gene3D G3DSA:3.20.20.140 1 338 8.6E-82 T 23-10-2018 VMUT_2323 c4ed0e911a8efc5a57db175ba6181b8f 339 SUPERFAMILY SSF51556 3 338 1.7E-69 T 23-10-2018 IPR032466 Metal-dependent hydrolase VMUT_1317 474e7ca5bafa4a69f0acea2f8d1847c5 727 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 7 706 9.2E-217 T 23-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 VMUT_1317 474e7ca5bafa4a69f0acea2f8d1847c5 727 Pfam PF03030 Inorganic H+ pyrophosphatase 14 700 4.0E-216 T 23-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 VMUT_1317 474e7ca5bafa4a69f0acea2f8d1847c5 727 PIRSF PIRSF001265 3 712 2.0E-216 T 23-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 VMUT_1317 474e7ca5bafa4a69f0acea2f8d1847c5 727 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 3 705 22.039 T 23-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 VMUT_0719 af1c25d3ab19688289a5933089ce97b7 199 Hamap MF_00234 Adenylate kinase [adkA]. 1 192 41.441 T 23-10-2018 IPR023477 Adenylate kinase AdkA GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 VMUT_0719 af1c25d3ab19688289a5933089ce97b7 199 Gene3D G3DSA:3.40.50.300 2 187 4.0E-47 T 23-10-2018 VMUT_0719 af1c25d3ab19688289a5933089ce97b7 199 SUPERFAMILY SSF52540 3 158 7.62E-16 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0719 af1c25d3ab19688289a5933089ce97b7 199 Pfam PF13207 AAA domain 8 142 1.1E-31 T 23-10-2018 VMUT_2264 5b078ea7d9e5da05e95ba2524737b302 363 Pfam PF00083 Sugar (and other) transporter 163 359 1.8E-10 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VMUT_2264 5b078ea7d9e5da05e95ba2524737b302 363 Pfam PF00083 Sugar (and other) transporter 4 152 2.3E-24 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VMUT_2264 5b078ea7d9e5da05e95ba2524737b302 363 ProSitePatterns PS00216 Sugar transport proteins signature 1. 226 242 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VMUT_2264 5b078ea7d9e5da05e95ba2524737b302 363 SUPERFAMILY SSF103473 2 358 1.57E-48 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_2264 5b078ea7d9e5da05e95ba2524737b302 363 ProSitePatterns PS00217 Sugar transport proteins signature 2. 62 87 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VMUT_2264 5b078ea7d9e5da05e95ba2524737b302 363 Gene3D G3DSA:1.20.1250.20 1 363 5.0E-58 T 23-10-2018 VMUT_1195 507da417e9eb3c65ad548d65f340baa1 687 Gene3D G3DSA:1.10.10.10 600 685 5.9E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_1195 507da417e9eb3c65ad548d65f340baa1 687 Pfam PF14551 MCM N-terminal domain 24 99 1.0E-9 T 23-10-2018 IPR027925 MCM N-terminal domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962|Reactome: R-HSA-69052 VMUT_1195 507da417e9eb3c65ad548d65f340baa1 687 Pfam PF00493 MCM2/3/5 family 271 594 8.1E-141 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 VMUT_1195 507da417e9eb3c65ad548d65f340baa1 687 SMART SM00350 103 595 3.1E-229 T 23-10-2018 IPR031327 Mini-chromosome maintenance protein VMUT_1195 507da417e9eb3c65ad548d65f340baa1 687 Gene3D G3DSA:2.20.28.10 134 184 3.7E-43 T 23-10-2018 VMUT_1195 507da417e9eb3c65ad548d65f340baa1 687 Gene3D G3DSA:2.40.50.140 110 255 3.7E-43 T 23-10-2018 VMUT_1195 507da417e9eb3c65ad548d65f340baa1 687 Gene3D G3DSA:3.30.1640.10 11 103 6.8E-15 T 23-10-2018 VMUT_1195 507da417e9eb3c65ad548d65f340baa1 687 SUPERFAMILY SSF52540 294 593 8.33E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1195 507da417e9eb3c65ad548d65f340baa1 687 Gene3D G3DSA:3.40.50.300 268 599 3.9E-138 T 23-10-2018 VMUT_1195 507da417e9eb3c65ad548d65f340baa1 687 SUPERFAMILY SSF50249 25 253 3.43E-59 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold VMUT_1195 507da417e9eb3c65ad548d65f340baa1 687 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 413 426 3.8E-31 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 VMUT_1195 507da417e9eb3c65ad548d65f340baa1 687 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 464 472 3.8E-31 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 VMUT_1195 507da417e9eb3c65ad548d65f340baa1 687 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 325 340 3.8E-31 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 VMUT_1195 507da417e9eb3c65ad548d65f340baa1 687 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 385 399 3.8E-31 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 VMUT_1195 507da417e9eb3c65ad548d65f340baa1 687 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 437 449 3.8E-31 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 VMUT_1195 507da417e9eb3c65ad548d65f340baa1 687 Pfam PF17207 MCM OB domain 107 232 1.2E-35 T 23-10-2018 IPR033762 MCM OB domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 VMUT_1980 c0606f96d7f0f38f570fc12aafb96b74 362 SUPERFAMILY SSF51998 1 360 5.68E-62 T 23-10-2018 VMUT_1980 c0606f96d7f0f38f570fc12aafb96b74 362 Pfam PF05167 Uncharacterised ACR (DUF711) 183 345 9.0E-35 T 23-10-2018 IPR007841 Uncharacterised protein family UPF0210 VMUT_1980 c0606f96d7f0f38f570fc12aafb96b74 362 Gene3D G3DSA:3.20.70.20 13 362 1.4E-51 T 23-10-2018 VMUT_1645 b91ef478575567c88687cf3a78652c6a 246 Gene3D G3DSA:3.60.20.10 5 246 8.9E-83 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VMUT_1645 b91ef478575567c88687cf3a78652c6a 246 SUPERFAMILY SSF56235 8 238 3.05E-77 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VMUT_1645 b91ef478575567c88687cf3a78652c6a 246 Pfam PF00227 Proteasome subunit 32 215 4.6E-59 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 VMUT_1645 b91ef478575567c88687cf3a78652c6a 246 TIGRFAM TIGR03633 arc_protsome_A: proteasome endopeptidase complex, archaeal, alpha subunit 8 235 1.4E-100 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 VMUT_1645 b91ef478575567c88687cf3a78652c6a 246 SMART SM00948 9 31 1.0E-8 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 VMUT_1645 b91ef478575567c88687cf3a78652c6a 246 Pfam PF10584 Proteasome subunit A N-terminal signature 9 31 5.8E-10 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 VMUT_1645 b91ef478575567c88687cf3a78652c6a 246 Hamap MF_00289_A Proteasome subunit alpha [prcA]. 4 234 44.682 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 VMUT_1069 30b47dff42c9736dad01d78a7a8bba99 300 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 66 257 6.7E-34 T 23-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 VMUT_1069 30b47dff42c9736dad01d78a7a8bba99 300 Gene3D G3DSA:3.40.50.620 38 294 3.0E-57 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_1069 30b47dff42c9736dad01d78a7a8bba99 300 SUPERFAMILY SSF52402 41 251 1.09E-43 T 23-10-2018 VMUT_1456 465628614be991cc4fea82393e644142 464 Pfam PF13380 CoA binding domain 12 135 1.5E-21 T 23-10-2018 IPR003781 CoA-binding GO:0048037 VMUT_1456 465628614be991cc4fea82393e644142 464 Gene3D G3DSA:3.40.50.261 300 460 2.0E-42 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VMUT_1456 465628614be991cc4fea82393e644142 464 SUPERFAMILY SSF52210 302 458 1.57E-31 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VMUT_1456 465628614be991cc4fea82393e644142 464 Gene3D G3DSA:3.40.50.261 131 299 5.6E-51 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VMUT_1456 465628614be991cc4fea82393e644142 464 SMART SM00881 8 102 5.3E-38 T 23-10-2018 IPR003781 CoA-binding GO:0048037 VMUT_1456 465628614be991cc4fea82393e644142 464 SUPERFAMILY SSF52210 130 303 3.01E-39 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VMUT_1456 465628614be991cc4fea82393e644142 464 Gene3D G3DSA:3.40.50.720 4 130 4.9E-41 T 23-10-2018 VMUT_1456 465628614be991cc4fea82393e644142 464 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 156 296 5.5E-46 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain VMUT_1456 465628614be991cc4fea82393e644142 464 SUPERFAMILY SSF51735 5 131 4.59E-37 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1684 2439c1105dfe4a7140894f850a8e5c7e 354 Gene3D G3DSA:3.40.50.300 2 136 4.8E-9 T 23-10-2018 VMUT_1684 2439c1105dfe4a7140894f850a8e5c7e 354 SUPERFAMILY SSF52540 4 339 2.06E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1684 2439c1105dfe4a7140894f850a8e5c7e 354 SMART SM00382 19 341 0.0017 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_1684 2439c1105dfe4a7140894f850a8e5c7e 354 Pfam PF13476 AAA domain 4 44 4.7E-8 T 23-10-2018 IPR038729 Rad50/SbcC-type AAA domain VMUT_0687 2ba1f43f452b603962f6522994b64d4e 64 Hamap MF_00773 50S ribosomal protein L24e [rpl24e]. 1 55 26.744 T 23-10-2018 IPR023438 Ribosomal protein L24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_0687 2ba1f43f452b603962f6522994b64d4e 64 Pfam PF01246 Ribosomal protein L24e 1 60 4.7E-22 T 23-10-2018 IPR000988 Ribosomal protein L24e-related VMUT_0687 2ba1f43f452b603962f6522994b64d4e 64 SUPERFAMILY SSF57716 5 53 9.98E-15 T 23-10-2018 VMUT_0687 2ba1f43f452b603962f6522994b64d4e 64 SMART SM00746 6 44 1.1E-11 T 23-10-2018 IPR011017 TRASH domain VMUT_0687 2ba1f43f452b603962f6522994b64d4e 64 Gene3D G3DSA:2.30.170.20 1 64 2.0E-24 T 23-10-2018 IPR038630 Ribosomal protein L24e/L24 superfamily VMUT_0687 2ba1f43f452b603962f6522994b64d4e 64 ProSitePatterns PS01073 Ribosomal protein L24e signature. 8 25 - T 23-10-2018 IPR023442 Ribosomal protein L24e, conserved site VMUT_0723 703dd7787876801c2a81458308bdbc67 260 Hamap MF_00304 Thiamine thiazole synthase [thi4]. 6 260 37.73 T 23-10-2018 IPR022828 Thiazole biosynthetic enzyme, prokaryotic VMUT_0723 703dd7787876801c2a81458308bdbc67 260 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 30 52 9.4E-6 T 23-10-2018 VMUT_0723 703dd7787876801c2a81458308bdbc67 260 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 179 9.4E-6 T 23-10-2018 VMUT_0723 703dd7787876801c2a81458308bdbc67 260 Pfam PF01946 Thi4 family 12 241 4.3E-72 T 23-10-2018 VMUT_0723 703dd7787876801c2a81458308bdbc67 260 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 31 50 2.0E-6 T 23-10-2018 VMUT_0723 703dd7787876801c2a81458308bdbc67 260 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 167 185 2.0E-6 T 23-10-2018 VMUT_0723 703dd7787876801c2a81458308bdbc67 260 Gene3D G3DSA:3.50.50.60 4 260 4.8E-88 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0723 703dd7787876801c2a81458308bdbc67 260 TIGRFAM TIGR00292 TIGR00292: thiazole biosynthesis enzyme 8 260 1.4E-90 T 23-10-2018 IPR002922 Thiazole biosynthetic enzyme Thi4 family VMUT_0723 703dd7787876801c2a81458308bdbc67 260 SUPERFAMILY SSF51905 5 259 1.43E-43 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_1217 06190d5a2cdf5634a857d2e0d6aa95da 107 ProSitePatterns PS01171 Ribosomal protein L21e signature. 37 62 - T 23-10-2018 IPR018259 Ribosomal protein L21e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1217 06190d5a2cdf5634a857d2e0d6aa95da 107 SUPERFAMILY SSF50104 3 94 2.08E-27 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily VMUT_1217 06190d5a2cdf5634a857d2e0d6aa95da 107 Hamap MF_00369 50S ribosomal protein L21e [rpl21e]. 2 96 24.853 T 23-10-2018 IPR022856 Ribosomal protein L21e, archaeal VMUT_1217 06190d5a2cdf5634a857d2e0d6aa95da 107 Gene3D G3DSA:2.30.30.70 1 94 2.8E-29 T 23-10-2018 IPR036948 Ribosomal protein L21 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1217 06190d5a2cdf5634a857d2e0d6aa95da 107 Pfam PF01157 Ribosomal protein L21e 4 92 6.2E-26 T 23-10-2018 IPR001147 Ribosomal protein L21e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0809 11fd979eefad0c946ec850bc88bc01a3 276 Gene3D G3DSA:3.40.50.150 6 201 7.4E-52 T 23-10-2018 VMUT_0809 11fd979eefad0c946ec850bc88bc01a3 276 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 52 79 - T 23-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 VMUT_0809 11fd979eefad0c946ec850bc88bc01a3 276 SUPERFAMILY SSF53335 18 269 1.27E-59 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_0809 11fd979eefad0c946ec850bc88bc01a3 276 SMART SM00650 38 200 2.2E-47 T 23-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 VMUT_0809 11fd979eefad0c946ec850bc88bc01a3 276 Pfam PF00398 Ribosomal RNA adenine dimethylase 23 266 1.3E-44 T 23-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm VMUT_0809 11fd979eefad0c946ec850bc88bc01a3 276 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 23 266 7.0E-63 T 23-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 VMUT_2176 9050c2d0d51e0fe070b63d8834132a7a 207 Gene3D G3DSA:2.40.30.70 47 191 9.3E-37 T 23-10-2018 IPR036414 YaeB, N-terminal domain superfamily VMUT_2176 9050c2d0d51e0fe070b63d8834132a7a 207 SUPERFAMILY SSF118196 47 201 3.14E-41 T 23-10-2018 IPR036413 YaeB-like superfamily VMUT_2176 9050c2d0d51e0fe070b63d8834132a7a 207 Pfam PF01980 Uncharacterised protein family UPF0066 71 181 4.1E-32 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain VMUT_2176 9050c2d0d51e0fe070b63d8834132a7a 207 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 44 181 4.9E-34 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain VMUT_0330 629d336f5d090597ebcc50178d854d2e 294 SUPERFAMILY SSF52540 6 207 1.81E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0330 629d336f5d090597ebcc50178d854d2e 294 SMART SM00382 28 209 7.8E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0330 629d336f5d090597ebcc50178d854d2e 294 Gene3D G3DSA:3.40.50.300 2 223 2.3E-57 T 23-10-2018 VMUT_0330 629d336f5d090597ebcc50178d854d2e 294 Pfam PF00005 ABC transporter 20 162 1.8E-25 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_0610 6683024d6b326e25f8b7dfc5ca6caf8a 338 SUPERFAMILY SSF50129 1 167 1.83E-49 T 23-10-2018 IPR011032 GroES-like superfamily VMUT_0610 6683024d6b326e25f8b7dfc5ca6caf8a 338 SUPERFAMILY SSF51735 138 309 8.34E-42 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0610 6683024d6b326e25f8b7dfc5ca6caf8a 338 Gene3D G3DSA:3.40.50.720 144 285 1.4E-99 T 23-10-2018 VMUT_0610 6683024d6b326e25f8b7dfc5ca6caf8a 338 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 130 3.5E-27 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VMUT_0610 6683024d6b326e25f8b7dfc5ca6caf8a 338 Gene3D G3DSA:3.90.180.10 16 324 1.4E-99 T 23-10-2018 VMUT_0610 6683024d6b326e25f8b7dfc5ca6caf8a 338 Pfam PF00107 Zinc-binding dehydrogenase 175 300 5.7E-23 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 VMUT_0610 6683024d6b326e25f8b7dfc5ca6caf8a 338 SMART SM00829 10 336 1.1E-12 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VMUT_2090 a3eae4077799ae13025064403b88d455 284 PIRSF PIRSF000887 10 269 2.8E-43 T 23-10-2018 IPR024173 Phosphoesterase, MJ0037 VMUT_2090 a3eae4077799ae13025064403b88d455 284 SUPERFAMILY SSF56300 18 212 1.22E-16 T 23-10-2018 VMUT_2090 a3eae4077799ae13025064403b88d455 284 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 20 166 1.3E-7 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 VMUT_2090 a3eae4077799ae13025064403b88d455 284 Gene3D G3DSA:3.60.21.10 17 178 2.1E-9 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like VMUT_0452 f891ea3add9714d65592d3fb0a678378 104 SUPERFAMILY SSF160350 2 91 7.98E-6 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 VMUT_1271 17735f6bc87e983f6ffe3645e6bb6ec6 61 Gene3D G3DSA:1.10.287.310 1 58 2.1E-17 T 23-10-2018 VMUT_1271 17735f6bc87e983f6ffe3645e6bb6ec6 61 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 52 11.721 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1271 17735f6bc87e983f6ffe3645e6bb6ec6 61 SUPERFAMILY SSF46561 2 54 1.2E-12 T 23-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1271 17735f6bc87e983f6ffe3645e6bb6ec6 61 TIGRFAM TIGR00012 L29: ribosomal protein uL29 1 52 2.2E-17 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1271 17735f6bc87e983f6ffe3645e6bb6ec6 61 ProSitePatterns PS00579 Ribosomal protein L29 signature. 31 45 - T 23-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1271 17735f6bc87e983f6ffe3645e6bb6ec6 61 Pfam PF00831 Ribosomal L29 protein 3 51 5.6E-15 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1799 8e740bcf81a0b770e2de0260c12c146d 50 Pfam PF09341 Transcription factor Pcc1 8 45 2.7E-5 T 23-10-2018 IPR015419 CTAG/Pcc1 family VMUT_1799 8e740bcf81a0b770e2de0260c12c146d 50 Gene3D G3DSA:3.30.310.50 1 48 1.0E-5 T 23-10-2018 VMUT_0565 f06655a8be7d4cb2ece440ec25d3a071 444 SUPERFAMILY SSF54862 302 367 1.65E-15 T 23-10-2018 VMUT_0565 f06655a8be7d4cb2ece440ec25d3a071 444 SUPERFAMILY SSF54862 92 161 4.76E-18 T 23-10-2018 VMUT_0565 f06655a8be7d4cb2ece440ec25d3a071 444 Pfam PF00037 4Fe-4S binding domain 134 156 9.3E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_0565 f06655a8be7d4cb2ece440ec25d3a071 444 Gene3D G3DSA:3.30.70.20 305 366 2.4E-13 T 23-10-2018 VMUT_0565 f06655a8be7d4cb2ece440ec25d3a071 444 Pfam PF13187 4Fe-4S dicluster domain 313 362 1.7E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_0565 f06655a8be7d4cb2ece440ec25d3a071 444 Gene3D G3DSA:3.30.70.20 104 185 1.4E-14 T 23-10-2018 VMUT_0565 f06655a8be7d4cb2ece440ec25d3a071 444 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 141 152 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_0565 f06655a8be7d4cb2ece440ec25d3a071 444 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 347 358 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_0565 f06655a8be7d4cb2ece440ec25d3a071 444 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 314 325 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_0301 1436c9a78394adee74b64deba077be13 542 Pfam PF01702 Queuine tRNA-ribosyltransferase 106 334 2.4E-39 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 VMUT_0301 1436c9a78394adee74b64deba077be13 542 Hamap MF_01634 tRNA-guanine(15) transglycosylase [tgtA]. 3 509 38.52 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 VMUT_0301 1436c9a78394adee74b64deba077be13 542 SUPERFAMILY SSF52141 384 512 2.09E-6 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VMUT_0301 1436c9a78394adee74b64deba077be13 542 Gene3D G3DSA:3.20.20.105 1 359 3.7E-98 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 VMUT_0301 1436c9a78394adee74b64deba077be13 542 Gene3D G3DSA:3.40.50.10630 370 533 1.3E-9 T 23-10-2018 VMUT_0301 1436c9a78394adee74b64deba077be13 542 SUPERFAMILY SSF51713 1 350 6.54E-99 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 VMUT_0301 1436c9a78394adee74b64deba077be13 542 SUPERFAMILY SSF88802 369 468 1.7E-12 T 23-10-2018 VMUT_0301 1436c9a78394adee74b64deba077be13 542 TIGRFAM TIGR00432 arcsn_tRNA_tgt: tRNA-guanine(15) transglycosylase 3 466 8.8E-127 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 VMUT_0301 1436c9a78394adee74b64deba077be13 542 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 3 336 4.1E-69 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 VMUT_1804 331a878bd1b71afccf86aefa39b9d6c1 505 Pfam PF00437 Type II/IV secretion system protein 123 390 7.2E-50 T 23-10-2018 IPR001482 Type II/IV secretion system protein VMUT_1804 331a878bd1b71afccf86aefa39b9d6c1 505 SUPERFAMILY SSF52540 103 415 1.16E-54 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1804 331a878bd1b71afccf86aefa39b9d6c1 505 Gene3D G3DSA:3.30.450.380 5 220 9.6E-73 T 23-10-2018 VMUT_1804 331a878bd1b71afccf86aefa39b9d6c1 505 Gene3D G3DSA:3.40.50.300 221 501 7.1E-95 T 23-10-2018 VMUT_1408 0bb0ed391497a95b20ef68fa9cc55e69 337 Pfam PF01895 PhoU domain 141 232 3.5E-15 T 23-10-2018 IPR026022 PhoU domain VMUT_1408 0bb0ed391497a95b20ef68fa9cc55e69 337 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 15 54 8.8E-8 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VMUT_1408 0bb0ed391497a95b20ef68fa9cc55e69 337 SUPERFAMILY SSF109755 135 333 1.26E-26 T 23-10-2018 VMUT_1408 0bb0ed391497a95b20ef68fa9cc55e69 337 SMART SM00966 11 56 2.4E-6 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VMUT_1408 0bb0ed391497a95b20ef68fa9cc55e69 337 Gene3D G3DSA:1.20.58.220 135 237 3.0E-16 T 23-10-2018 IPR038078 PhoU-like domain superfamily VMUT_1408 0bb0ed391497a95b20ef68fa9cc55e69 337 SUPERFAMILY SSF89447 14 53 8.02E-6 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily VMUT_1377 80a05a1d23285aa973665e53e99861c6 181 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 100 162 1.0E-14 T 23-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal VMUT_1377 80a05a1d23285aa973665e53e99861c6 181 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 63 99 3.9E-13 T 23-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal VMUT_1377 80a05a1d23285aa973665e53e99861c6 181 SUPERFAMILY SSF50249 40 171 1.63E-36 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold VMUT_1377 80a05a1d23285aa973665e53e99861c6 181 Gene3D G3DSA:1.10.12.20 33 103 1.4E-16 T 23-10-2018 VMUT_0022 b6c9172fd308470cd172db3e3ca28824 430 Pfam PF00083 Sugar (and other) transporter 34 423 3.7E-52 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VMUT_0022 b6c9172fd308470cd172db3e3ca28824 430 Gene3D G3DSA:1.20.1250.20 1 430 2.9E-79 T 23-10-2018 VMUT_0022 b6c9172fd308470cd172db3e3ca28824 430 ProSitePatterns PS00216 Sugar transport proteins signature 1. 55 72 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VMUT_0022 b6c9172fd308470cd172db3e3ca28824 430 ProSitePatterns PS00217 Sugar transport proteins signature 2. 97 122 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VMUT_0022 b6c9172fd308470cd172db3e3ca28824 430 SUPERFAMILY SSF103473 2 427 8.76E-72 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_2211 3666cf7213e4b452a28c70b6836ed7df 277 SUPERFAMILY SSF143744 153 271 3.4E-19 T 23-10-2018 IPR038084 GlcG-like domain superfamily VMUT_2211 3666cf7213e4b452a28c70b6836ed7df 277 Gene3D G3DSA:3.30.450.150 2 137 1.6E-36 T 23-10-2018 IPR038084 GlcG-like domain superfamily VMUT_2211 3666cf7213e4b452a28c70b6836ed7df 277 Pfam PF03928 Haem-degrading 7 132 1.9E-26 T 23-10-2018 IPR005624 Haem-degrading VMUT_2211 3666cf7213e4b452a28c70b6836ed7df 277 Pfam PF03928 Haem-degrading 153 267 2.1E-16 T 23-10-2018 IPR005624 Haem-degrading VMUT_2211 3666cf7213e4b452a28c70b6836ed7df 277 SUPERFAMILY SSF143744 5 136 3.27E-30 T 23-10-2018 IPR038084 GlcG-like domain superfamily VMUT_2211 3666cf7213e4b452a28c70b6836ed7df 277 Gene3D G3DSA:3.30.450.150 146 274 1.3E-22 T 23-10-2018 IPR038084 GlcG-like domain superfamily VMUT_1761 21c8349c11c2f5571f44c411a790394a 184 Hamap MF_01371_A 50S ribosomal protein L30 [rpmD]. 1 184 69.156 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 VMUT_1761 21c8349c11c2f5571f44c411a790394a 184 Pfam PF00327 Ribosomal protein L30p/L7e 19 68 1.6E-11 T 23-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain VMUT_1761 21c8349c11c2f5571f44c411a790394a 184 Gene3D G3DSA:3.30.1390.20 19 172 2.9E-39 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily VMUT_1761 21c8349c11c2f5571f44c411a790394a 184 Gene3D G3DSA:1.10.15.30 74 144 2.9E-39 T 23-10-2018 IPR023106 Ribosomal protein L30, central domain, archaeal type VMUT_1761 21c8349c11c2f5571f44c411a790394a 184 SUPERFAMILY SSF55129 19 183 5.86E-38 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily VMUT_1761 21c8349c11c2f5571f44c411a790394a 184 TIGRFAM TIGR01309 uL30_arch: ribosomal protein uL30 19 184 1.3E-48 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 VMUT_0242 71eef512c484d5b75a6144bbd9d5d9e5 532 SUPERFAMILY SSF51338 5 527 1.24E-11 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VMUT_0242 71eef512c484d5b75a6144bbd9d5d9e5 532 Pfam PF07969 Amidohydrolase family 53 527 2.9E-103 T 23-10-2018 IPR013108 Amidohydrolase 3 VMUT_0242 71eef512c484d5b75a6144bbd9d5d9e5 532 Gene3D G3DSA:3.10.310.70 81 196 8.2E-143 T 23-10-2018 VMUT_0242 71eef512c484d5b75a6144bbd9d5d9e5 532 Gene3D G3DSA:2.30.40.10 9 504 8.2E-143 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VMUT_0242 71eef512c484d5b75a6144bbd9d5d9e5 532 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 64 72 - T 23-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 VMUT_0242 71eef512c484d5b75a6144bbd9d5d9e5 532 Gene3D G3DSA:3.20.20.140 63 486 8.2E-143 T 23-10-2018 VMUT_0242 71eef512c484d5b75a6144bbd9d5d9e5 532 SUPERFAMILY SSF51556 62 486 8.75E-37 T 23-10-2018 IPR032466 Metal-dependent hydrolase VMUT_1131 e9bbe4fd7ea4aa9dc42c7fa41a858a93 472 SUPERFAMILY SSF102114 154 395 9.81E-53 T 23-10-2018 VMUT_1131 e9bbe4fd7ea4aa9dc42c7fa41a858a93 472 SUPERFAMILY SSF52242 29 129 1.33E-12 T 23-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 VMUT_1131 e9bbe4fd7ea4aa9dc42c7fa41a858a93 472 Gene3D G3DSA:3.80.30.20 198 422 5.9E-34 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe VMUT_1131 e9bbe4fd7ea4aa9dc42c7fa41a858a93 472 SMART SM00729 198 409 3.6E-41 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VMUT_1131 e9bbe4fd7ea4aa9dc42c7fa41a858a93 472 Gene3D G3DSA:3.40.50.280 31 147 3.3E-15 T 23-10-2018 VMUT_1131 e9bbe4fd7ea4aa9dc42c7fa41a858a93 472 Pfam PF04055 Radical SAM superfamily 205 364 8.7E-24 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_1131 e9bbe4fd7ea4aa9dc42c7fa41a858a93 472 Pfam PF02310 B12 binding domain 21 134 1.1E-27 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 VMUT_0006 47fb12ff49cf49103dba2a240611ea94 451 Pfam PF13969 Pab87 octamerisation domain 354 448 1.2E-25 T 23-10-2018 IPR025879 Pab87 octamerisation domain VMUT_0006 47fb12ff49cf49103dba2a240611ea94 451 SUPERFAMILY SSF56601 5 340 1.79E-83 T 23-10-2018 IPR012338 Beta-lactamase/transpeptidase-like VMUT_0006 47fb12ff49cf49103dba2a240611ea94 451 Pfam PF00144 Beta-lactamase 16 335 2.2E-64 T 23-10-2018 IPR001466 Beta-lactamase-related VMUT_0006 47fb12ff49cf49103dba2a240611ea94 451 Gene3D G3DSA:3.40.710.10 1 351 8.1E-121 T 23-10-2018 VMUT_0006 47fb12ff49cf49103dba2a240611ea94 451 Gene3D G3DSA:2.40.128.210 352 450 5.6E-28 T 23-10-2018 IPR038164 Pab87 octamerisation domain superfamily VMUT_0128 4bc6ccdf38a5f620b71a325a01606574 386 Pfam PF05559 Protein of unknown function (DUF763) 5 335 2.8E-117 T 23-10-2018 IPR008482 Protein of unknown function DUF763 VMUT_0113 259a9314f79105e850a9ec2139ca1b49 331 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 139 198 5.1E-5 T 23-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 VMUT_0113 259a9314f79105e850a9ec2139ca1b49 331 Gene3D G3DSA:3.40.50.720 6 303 1.7E-62 T 23-10-2018 VMUT_0113 259a9314f79105e850a9ec2139ca1b49 331 SUPERFAMILY SSF51735 3 147 1.23E-34 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0113 259a9314f79105e850a9ec2139ca1b49 331 Gene3D G3DSA:3.30.360.10 128 319 1.7E-62 T 23-10-2018 VMUT_0113 259a9314f79105e850a9ec2139ca1b49 331 SUPERFAMILY SSF55347 128 292 8.01E-27 T 23-10-2018 VMUT_0113 259a9314f79105e850a9ec2139ca1b49 331 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 121 7.4E-18 T 23-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 VMUT_1125 c11b60e44135dfe6ea4eb429b16a3a63 783 Gene3D G3DSA:3.90.1170.50 2 124 1.2E-24 T 23-10-2018 VMUT_1125 c11b60e44135dfe6ea4eb429b16a3a63 783 Gene3D G3DSA:3.30.365.10 139 348 4.3E-58 T 23-10-2018 VMUT_1125 c11b60e44135dfe6ea4eb429b16a3a63 783 Gene3D G3DSA:3.30.365.10 180 275 4.3E-58 T 23-10-2018 VMUT_1125 c11b60e44135dfe6ea4eb429b16a3a63 783 SUPERFAMILY SSF56003 126 782 1.44E-144 T 23-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 VMUT_1125 c11b60e44135dfe6ea4eb429b16a3a63 783 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 140 718 5.3E-126 T 23-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 VMUT_1125 c11b60e44135dfe6ea4eb429b16a3a63 783 SUPERFAMILY SSF54665 8 129 9.29E-30 T 23-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily VMUT_1125 c11b60e44135dfe6ea4eb429b16a3a63 783 SMART SM01008 15 125 7.6E-29 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead VMUT_1125 c11b60e44135dfe6ea4eb429b16a3a63 783 Gene3D G3DSA:3.30.365.10 363 777 6.2E-88 T 23-10-2018 VMUT_1125 c11b60e44135dfe6ea4eb429b16a3a63 783 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 15 124 8.3E-17 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead VMUT_1125 c11b60e44135dfe6ea4eb429b16a3a63 783 Gene3D G3DSA:3.30.365.10 448 635 6.2E-88 T 23-10-2018 VMUT_0437 36151c1e2914d639fc2d981943ab9b9a 341 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 158 185 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 VMUT_0437 36151c1e2914d639fc2d981943ab9b9a 341 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 235 251 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site VMUT_0437 36151c1e2914d639fc2d981943ab9b9a 341 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 119 296 2.3E-64 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 VMUT_0437 36151c1e2914d639fc2d981943ab9b9a 341 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 43 327 3.9E-28 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 VMUT_0437 36151c1e2914d639fc2d981943ab9b9a 341 SUPERFAMILY SSF52283 42 146 1.7E-24 T 23-10-2018 VMUT_0437 36151c1e2914d639fc2d981943ab9b9a 341 Gene3D G3DSA:3.40.50.720 108 296 3.2E-112 T 23-10-2018 VMUT_0437 36151c1e2914d639fc2d981943ab9b9a 341 Gene3D G3DSA:3.40.50.720 37 323 3.2E-112 T 23-10-2018 VMUT_0437 36151c1e2914d639fc2d981943ab9b9a 341 SUPERFAMILY SSF51735 113 296 2.27E-61 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0872 50b3517863688770442687def183add0 147 SUPERFAMILY SSF54631 18 139 1.02E-33 T 23-10-2018 VMUT_0872 50b3517863688770442687def183add0 147 SMART SM00116 93 140 9.1E-11 T 23-10-2018 IPR000644 CBS domain VMUT_0872 50b3517863688770442687def183add0 147 SMART SM00116 29 77 1.1E-5 T 23-10-2018 IPR000644 CBS domain VMUT_0872 50b3517863688770442687def183add0 147 Gene3D G3DSA:3.10.580.10 16 145 1.5E-37 T 23-10-2018 VMUT_0872 50b3517863688770442687def183add0 147 Pfam PF00571 CBS domain 23 77 1.7E-10 T 23-10-2018 IPR000644 CBS domain VMUT_0872 50b3517863688770442687def183add0 147 Pfam PF00571 CBS domain 89 140 3.2E-14 T 23-10-2018 IPR000644 CBS domain VMUT_2060 2ccf0e98d4323c435c665ac0797f0cd6 391 Gene3D G3DSA:1.10.150.390 340 384 1.7E-17 T 23-10-2018 VMUT_2060 2ccf0e98d4323c435c665ac0797f0cd6 391 SUPERFAMILY SSF64484 36 389 3.2E-90 T 23-10-2018 VMUT_2060 2ccf0e98d4323c435c665ac0797f0cd6 391 Hamap MF_00411 DNA-directed RNA polymerase subunit A'' [rpoA2]. 9 391 39.787 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_2060 2ccf0e98d4323c435c665ac0797f0cd6 391 Pfam PF04998 RNA polymerase Rpb1, domain 5 45 336 4.1E-51 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_2060 2ccf0e98d4323c435c665ac0797f0cd6 391 TIGRFAM TIGR02389 RNA_pol_rpoA2: DNA-directed RNA polymerase, subunit A'' 23 388 3.7E-145 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_0940 b94f017273dd7b9a22a997b34cc69df8 349 SMART SM00279 228 262 1.7E-9 T 23-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 VMUT_0940 b94f017273dd7b9a22a997b34cc69df8 349 Gene3D G3DSA:3.40.50.1010 2 349 1.0E-94 T 23-10-2018 VMUT_0940 b94f017273dd7b9a22a997b34cc69df8 349 Pfam PF00752 XPG N-terminal domain 1 104 4.3E-19 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 VMUT_0940 b94f017273dd7b9a22a997b34cc69df8 349 SUPERFAMILY SSF88723 2 223 6.54E-58 T 23-10-2018 IPR029060 PIN-like domain superfamily VMUT_0940 b94f017273dd7b9a22a997b34cc69df8 349 SMART SM00485 1 105 7.7E-42 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 VMUT_0940 b94f017273dd7b9a22a997b34cc69df8 349 SUPERFAMILY SSF47807 230 348 3.74E-28 T 23-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily VMUT_0940 b94f017273dd7b9a22a997b34cc69df8 349 TIGRFAM TIGR03674 fen_arch: flap structure-specific endonuclease 1 348 1.0E-135 T 23-10-2018 IPR019973 Flap structure-specific endonuclease, archaea GO:0016788 VMUT_0940 b94f017273dd7b9a22a997b34cc69df8 349 Hamap MF_00614 Flap endonuclease 1 [fen]. 1 349 136.175 T 23-10-2018 IPR023426 Flap endonuclease 1 GO:0016788 Reactome: R-HSA-110362|Reactome: R-HSA-162594|Reactome: R-HSA-174437|Reactome: R-HSA-5651801|Reactome: R-HSA-5685939|Reactome: R-HSA-69166 VMUT_0940 b94f017273dd7b9a22a997b34cc69df8 349 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 164 184 4.7E-25 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 VMUT_0940 b94f017273dd7b9a22a997b34cc69df8 349 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 231 246 4.7E-25 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 VMUT_0940 b94f017273dd7b9a22a997b34cc69df8 349 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 79 98 4.7E-25 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 VMUT_0940 b94f017273dd7b9a22a997b34cc69df8 349 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 143 160 4.7E-25 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 VMUT_0940 b94f017273dd7b9a22a997b34cc69df8 349 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 25 39 4.7E-25 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 VMUT_0940 b94f017273dd7b9a22a997b34cc69df8 349 SMART SM00484 144 225 1.7E-27 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 VMUT_0940 b94f017273dd7b9a22a997b34cc69df8 349 Pfam PF00867 XPG I-region 145 241 2.6E-23 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 VMUT_1462 aaef039b75cc1ad1ef5770c6619fddf4 104 SUPERFAMILY SSF46785 11 72 2.22E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_1462 aaef039b75cc1ad1ef5770c6619fddf4 104 Pfam PF13412 Winged helix-turn-helix DNA-binding 12 59 3.1E-14 T 23-10-2018 VMUT_1462 aaef039b75cc1ad1ef5770c6619fddf4 104 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 39 3.2E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VMUT_1462 aaef039b75cc1ad1ef5770c6619fddf4 104 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 12 28 3.2E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VMUT_1462 aaef039b75cc1ad1ef5770c6619fddf4 104 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 39 58 3.2E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VMUT_1462 aaef039b75cc1ad1ef5770c6619fddf4 104 Gene3D G3DSA:1.10.10.10 8 63 9.3E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_1462 aaef039b75cc1ad1ef5770c6619fddf4 104 SMART SM00344 12 100 4.6E-6 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 VMUT_0082 f65fc806076c8ac6ff1b24c18b4b4bd1 326 Pfam PF00005 ABC transporter 23 186 2.7E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_0082 f65fc806076c8ac6ff1b24c18b4b4bd1 326 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VMUT_0082 f65fc806076c8ac6ff1b24c18b4b4bd1 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 304 5.0E-17 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VMUT_0082 f65fc806076c8ac6ff1b24c18b4b4bd1 326 SMART SM00382 32 243 1.7E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0082 f65fc806076c8ac6ff1b24c18b4b4bd1 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 323 5.0E-25 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VMUT_0082 f65fc806076c8ac6ff1b24c18b4b4bd1 326 SUPERFAMILY SSF52540 3 262 2.72E-62 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0082 f65fc806076c8ac6ff1b24c18b4b4bd1 326 Gene3D G3DSA:3.40.50.300 1 325 9.5E-90 T 23-10-2018 VMUT_1995 7fc992ccf16889d91eefa033c70e979a 208 Pfam PF00753 Metallo-beta-lactamase superfamily 14 186 4.9E-29 T 23-10-2018 IPR001279 Metallo-beta-lactamase VMUT_1995 7fc992ccf16889d91eefa033c70e979a 208 SMART SM00849 17 186 4.1E-34 T 23-10-2018 IPR001279 Metallo-beta-lactamase VMUT_1995 7fc992ccf16889d91eefa033c70e979a 208 SUPERFAMILY SSF56281 9 196 5.96E-45 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_1995 7fc992ccf16889d91eefa033c70e979a 208 Gene3D G3DSA:3.60.15.10 6 206 7.9E-61 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_1549 b2a9881e75bcf0a4ae495daff56f0ac7 414 Gene3D G3DSA:3.30.830.10 2 212 3.9E-54 T 23-10-2018 VMUT_1549 b2a9881e75bcf0a4ae495daff56f0ac7 414 SUPERFAMILY SSF63411 222 408 2.5E-13 T 23-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 VMUT_1549 b2a9881e75bcf0a4ae495daff56f0ac7 414 Pfam PF00675 Insulinase (Peptidase family M16) 13 148 5.9E-15 T 23-10-2018 IPR011765 Peptidase M16, N-terminal VMUT_1549 b2a9881e75bcf0a4ae495daff56f0ac7 414 SUPERFAMILY SSF63411 5 208 2.44E-50 T 23-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 VMUT_1549 b2a9881e75bcf0a4ae495daff56f0ac7 414 Gene3D G3DSA:3.30.830.10 221 413 9.6E-17 T 23-10-2018 VMUT_1549 b2a9881e75bcf0a4ae495daff56f0ac7 414 Pfam PF05193 Peptidase M16 inactive domain 164 321 3.8E-17 T 23-10-2018 IPR007863 Peptidase M16, C-terminal VMUT_0520 3c1a634c3b1580dec3ead4e5154d06e0 335 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 153 173 - T 23-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 VMUT_0520 3c1a634c3b1580dec3ead4e5154d06e0 335 SUPERFAMILY SSF51905 23 324 2.77E-47 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0520 3c1a634c3b1580dec3ead4e5154d06e0 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 307 326 6.9E-60 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VMUT_0520 3c1a634c3b1580dec3ead4e5154d06e0 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 251 272 6.9E-60 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VMUT_0520 3c1a634c3b1580dec3ead4e5154d06e0 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 161 185 6.9E-60 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VMUT_0520 3c1a634c3b1580dec3ead4e5154d06e0 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 58 73 6.9E-60 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VMUT_0520 3c1a634c3b1580dec3ead4e5154d06e0 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 78 88 6.9E-60 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VMUT_0520 3c1a634c3b1580dec3ead4e5154d06e0 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 124 132 6.9E-60 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VMUT_0520 3c1a634c3b1580dec3ead4e5154d06e0 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 146 158 6.9E-60 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VMUT_0520 3c1a634c3b1580dec3ead4e5154d06e0 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 26 48 6.9E-60 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VMUT_0520 3c1a634c3b1580dec3ead4e5154d06e0 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 213 229 6.9E-60 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VMUT_0520 3c1a634c3b1580dec3ead4e5154d06e0 335 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 25 315 5.8E-46 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VMUT_0520 3c1a634c3b1580dec3ead4e5154d06e0 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 27 46 1.8E-31 T 23-10-2018 VMUT_0520 3c1a634c3b1580dec3ead4e5154d06e0 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 276 298 1.8E-31 T 23-10-2018 VMUT_0520 3c1a634c3b1580dec3ead4e5154d06e0 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 165 183 1.8E-31 T 23-10-2018 VMUT_0520 3c1a634c3b1580dec3ead4e5154d06e0 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 123 141 1.8E-31 T 23-10-2018 VMUT_0520 3c1a634c3b1580dec3ead4e5154d06e0 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 249 265 1.8E-31 T 23-10-2018 VMUT_0520 3c1a634c3b1580dec3ead4e5154d06e0 335 Gene3D G3DSA:3.50.50.60 135 257 7.3E-111 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0520 3c1a634c3b1580dec3ead4e5154d06e0 335 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 25 326 2.0E-105 T 23-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 VMUT_0520 3c1a634c3b1580dec3ead4e5154d06e0 335 Gene3D G3DSA:3.50.50.60 25 322 7.3E-111 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0051 3f858eeeef025b4d3b45602ef8c0f45a 125 Gene3D G3DSA:3.30.420.130 1 123 1.5E-23 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily VMUT_0051 3f858eeeef025b4d3b45602ef8c0f45a 125 SUPERFAMILY SSF53146 1 118 1.44E-24 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily VMUT_0051 3f858eeeef025b4d3b45602ef8c0f45a 125 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 16 111 1.2E-16 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis VMUT_0196 b4d10f1a26944b3a5769f08ccdfb908b 305 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 3 300 8.5E-100 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VMUT_0196 b4d10f1a26944b3a5769f08ccdfb908b 305 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 2 300 35.663 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VMUT_0196 b4d10f1a26944b3a5769f08ccdfb908b 305 SUPERFAMILY SSF54782 224 303 1.57E-18 T 23-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VMUT_0196 b4d10f1a26944b3a5769f08ccdfb908b 305 Gene3D G3DSA:3.30.160.40 225 304 3.6E-13 T 23-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VMUT_0196 b4d10f1a26944b3a5769f08ccdfb908b 305 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 230 298 1.3E-14 T 23-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VMUT_0196 b4d10f1a26944b3a5769f08ccdfb908b 305 SUPERFAMILY SSF53850 1 220 1.09E-67 T 23-10-2018 VMUT_0196 b4d10f1a26944b3a5769f08ccdfb908b 305 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 234 250 - T 23-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VMUT_0196 b4d10f1a26944b3a5769f08ccdfb908b 305 PRINTS PR00151 Porphobilinogen deaminase signature 233 250 3.0E-37 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VMUT_0196 b4d10f1a26944b3a5769f08ccdfb908b 305 PRINTS PR00151 Porphobilinogen deaminase signature 142 159 3.0E-37 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VMUT_0196 b4d10f1a26944b3a5769f08ccdfb908b 305 PRINTS PR00151 Porphobilinogen deaminase signature 42 62 3.0E-37 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VMUT_0196 b4d10f1a26944b3a5769f08ccdfb908b 305 PRINTS PR00151 Porphobilinogen deaminase signature 73 92 3.0E-37 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VMUT_0196 b4d10f1a26944b3a5769f08ccdfb908b 305 PRINTS PR00151 Porphobilinogen deaminase signature 123 140 3.0E-37 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VMUT_0196 b4d10f1a26944b3a5769f08ccdfb908b 305 PIRSF PIRSF001438 1 305 3.2E-92 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VMUT_0196 b4d10f1a26944b3a5769f08ccdfb908b 305 Gene3D G3DSA:3.40.190.10 3 213 5.9E-67 T 23-10-2018 VMUT_0196 b4d10f1a26944b3a5769f08ccdfb908b 305 Gene3D G3DSA:3.40.190.10 100 205 5.9E-67 T 23-10-2018 VMUT_0196 b4d10f1a26944b3a5769f08ccdfb908b 305 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 3 215 1.2E-64 T 23-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VMUT_0231 049c1ce290e3919ebdb6c27db4e8786c 92 Pfam PF02597 ThiS family 5 85 9.0E-13 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 VMUT_0231 049c1ce290e3919ebdb6c27db4e8786c 92 Gene3D G3DSA:3.10.20.30 1 89 1.1E-17 T 23-10-2018 IPR012675 Beta-grasp domain superfamily VMUT_0231 049c1ce290e3919ebdb6c27db4e8786c 92 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 4 88 9.4E-14 T 23-10-2018 IPR010038 MoaD, archaeal-type VMUT_0231 049c1ce290e3919ebdb6c27db4e8786c 92 SUPERFAMILY SSF54285 1 87 1.46E-14 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp VMUT_1697 f2959c3fbf3ca78d0ce13ddb6b7c44ec 119 Gene3D G3DSA:2.40.70.10 1 113 3.8E-11 T 23-10-2018 IPR021109 Aspartic peptidase domain superfamily VMUT_1697 f2959c3fbf3ca78d0ce13ddb6b7c44ec 119 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 23 34 - T 23-10-2018 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 VMUT_1697 f2959c3fbf3ca78d0ce13ddb6b7c44ec 119 Pfam PF13975 gag-polyprotein putative aspartyl protease 20 96 6.1E-9 T 23-10-2018 VMUT_1697 f2959c3fbf3ca78d0ce13ddb6b7c44ec 119 SUPERFAMILY SSF50630 20 102 5.3E-9 T 23-10-2018 IPR021109 Aspartic peptidase domain superfamily VMUT_0802 0c7932dcf41415e45cbdf2e95b77561b 618 SMART SM00436 135 233 3.0E-28 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 VMUT_0802 0c7932dcf41415e45cbdf2e95b77561b 618 Pfam PF01751 Toprim domain 6 142 4.2E-15 T 23-10-2018 IPR006171 TOPRIM domain VMUT_0802 0c7932dcf41415e45cbdf2e95b77561b 618 Pfam PF01131 DNA topoisomerase 160 573 1.8E-105 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 VMUT_0802 0c7932dcf41415e45cbdf2e95b77561b 618 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 401 417 3.9E-19 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 VMUT_0802 0c7932dcf41415e45cbdf2e95b77561b 618 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 203 221 3.9E-19 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 VMUT_0802 0c7932dcf41415e45cbdf2e95b77561b 618 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 106 119 3.9E-19 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 VMUT_0802 0c7932dcf41415e45cbdf2e95b77561b 618 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 320 329 3.9E-19 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 VMUT_0802 0c7932dcf41415e45cbdf2e95b77561b 618 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 499 513 3.9E-19 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 VMUT_0802 0c7932dcf41415e45cbdf2e95b77561b 618 SMART SM00437 278 536 2.1E-63 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 VMUT_0802 0c7932dcf41415e45cbdf2e95b77561b 618 Gene3D G3DSA:1.10.460.10 167 585 1.5E-120 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 VMUT_0802 0c7932dcf41415e45cbdf2e95b77561b 618 Gene3D G3DSA:3.40.50.140 1 157 6.6E-35 T 23-10-2018 VMUT_0802 0c7932dcf41415e45cbdf2e95b77561b 618 Gene3D G3DSA:2.70.20.10 227 483 1.5E-120 T 23-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 VMUT_0802 0c7932dcf41415e45cbdf2e95b77561b 618 SMART SM00493 4 132 1.5E-10 T 23-10-2018 IPR006171 TOPRIM domain VMUT_0802 0c7932dcf41415e45cbdf2e95b77561b 618 Gene3D G3DSA:1.10.290.10 286 415 1.5E-120 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 VMUT_0802 0c7932dcf41415e45cbdf2e95b77561b 618 SUPERFAMILY SSF56712 5 587 2.88E-141 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain VMUT_0688 4cb3c44cc6e93ac29dbf5177bfc764d4 171 Gene3D G3DSA:3.90.79.10 2 170 3.1E-39 T 23-10-2018 VMUT_0688 4cb3c44cc6e93ac29dbf5177bfc764d4 171 SUPERFAMILY SSF55811 3 166 1.9E-39 T 23-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 VMUT_0688 4cb3c44cc6e93ac29dbf5177bfc764d4 171 PRINTS PR00502 NUDIX hydrolase family signature 76 91 7.6E-6 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 VMUT_0688 4cb3c44cc6e93ac29dbf5177bfc764d4 171 PRINTS PR00502 NUDIX hydrolase family signature 62 76 7.6E-6 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 VMUT_0688 4cb3c44cc6e93ac29dbf5177bfc764d4 171 ProSitePatterns PS00893 Nudix box signature. 67 88 - T 23-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 VMUT_0688 4cb3c44cc6e93ac29dbf5177bfc764d4 171 Pfam PF00293 NUDIX domain 34 142 1.9E-16 T 23-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 VMUT_1175 39e67f992c699d5772104b4958b51a12 618 SMART SM00790 5 211 1.2E-90 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_1175 39e67f992c699d5772104b4958b51a12 618 Gene3D G3DSA:1.10.569.10 247 428 4.0E-111 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 VMUT_1175 39e67f992c699d5772104b4958b51a12 618 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 229 611 8.7E-117 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_1175 39e67f992c699d5772104b4958b51a12 618 Gene3D G3DSA:3.60.9.10 3 213 3.0E-70 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily VMUT_1175 39e67f992c699d5772104b4958b51a12 618 Gene3D G3DSA:1.10.599.10 245 611 4.0E-111 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 VMUT_1175 39e67f992c699d5772104b4958b51a12 618 SUPERFAMILY SSF56228 6 211 1.44E-61 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily VMUT_1175 39e67f992c699d5772104b4958b51a12 618 SUPERFAMILY SSF48310 219 614 2.22E-115 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_1175 39e67f992c699d5772104b4958b51a12 618 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 7 209 5.3E-69 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_0424 d190f31fef31a532e3f2fd93473d8074 289 Gene3D G3DSA:3.20.20.140 1 284 1.2E-42 T 23-10-2018 VMUT_0424 d190f31fef31a532e3f2fd93473d8074 289 Pfam PF04909 Amidohydrolase 4 282 1.0E-28 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VMUT_0424 d190f31fef31a532e3f2fd93473d8074 289 SUPERFAMILY SSF51556 4 283 3.18E-36 T 23-10-2018 IPR032466 Metal-dependent hydrolase VMUT_0502 73e77903a316c304999a642dfef9ac36 378 SUPERFAMILY SSF56014 127 359 9.68E-31 T 23-10-2018 VMUT_0502 73e77903a316c304999a642dfef9ac36 378 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 129 354 1.1E-31 T 23-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VMUT_0502 73e77903a316c304999a642dfef9ac36 378 Gene3D G3DSA:3.30.413.10 135 359 1.0E-73 T 23-10-2018 VMUT_0502 73e77903a316c304999a642dfef9ac36 378 TIGRFAM TIGR02066 dsrB: sulfite reductase, dissimilatory-type beta subunit 31 360 5.6E-113 T 23-10-2018 IPR011808 Sulphite reductase, dissimilatory-type beta subunit GO:0006790|GO:0009055|GO:0018551|GO:0051539 KEGG: 00633+1.8.99.5|KEGG: 00920+1.8.99.5|MetaCyc: PWY-5306|MetaCyc: PWY-5360 VMUT_0502 73e77903a316c304999a642dfef9ac36 378 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 53 120 9.8E-8 T 23-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VMUT_0502 73e77903a316c304999a642dfef9ac36 378 Gene3D G3DSA:3.30.70.20 203 272 1.0E-73 T 23-10-2018 VMUT_0502 73e77903a316c304999a642dfef9ac36 378 SUPERFAMILY SSF54862 232 271 6.28E-8 T 23-10-2018 VMUT_0502 73e77903a316c304999a642dfef9ac36 378 SUPERFAMILY SSF55124 11 135 3.05E-33 T 23-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VMUT_0502 73e77903a316c304999a642dfef9ac36 378 Gene3D G3DSA:3.30.70.3340 4 132 3.4E-36 T 23-10-2018 VMUT_0263 234a4c382fd97f7e09a0174746d37f8e 158 PIRSF PIRSF002134 1 150 1.6E-38 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0263 234a4c382fd97f7e09a0174746d37f8e 158 Pfam PF00416 Ribosomal protein S13/S18 10 136 9.3E-35 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0263 234a4c382fd97f7e09a0174746d37f8e 158 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 8 147 22.715 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0263 234a4c382fd97f7e09a0174746d37f8e 158 ProSitePatterns PS00646 Ribosomal protein S13 signature. 116 129 - T 23-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0263 234a4c382fd97f7e09a0174746d37f8e 158 SUPERFAMILY SSF46946 9 147 1.61E-30 T 23-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 VMUT_0263 234a4c382fd97f7e09a0174746d37f8e 158 Gene3D G3DSA:4.10.910.10 88 137 9.6E-17 T 23-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0263 234a4c382fd97f7e09a0174746d37f8e 158 TIGRFAM TIGR03629 uS13_arch: ribosomal protein uS13 4 146 6.0E-57 T 23-10-2018 IPR019977 Ribosomal protein S13, archaeal GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_0263 234a4c382fd97f7e09a0174746d37f8e 158 Gene3D G3DSA:1.10.8.50 1 74 8.8E-19 T 23-10-2018 VMUT_0144 13297562aab57f4614a7c8408ea370f0 225 SUPERFAMILY SSF55821 2 214 6.41E-54 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily VMUT_0144 13297562aab57f4614a7c8408ea370f0 225 Gene3D G3DSA:3.90.870.10 1 224 2.8E-58 T 23-10-2018 VMUT_0144 13297562aab57f4614a7c8408ea370f0 225 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 3 214 4.5E-47 T 23-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VMUT_0737 e2ac7ed840fdda2ee2d24f9f1da50337 338 TIGRFAM TIGR02128 G6PI_arch: bifunctional phosphoglucose/phosphomannose isomerase 40 330 2.7E-64 T 23-10-2018 IPR011857 Bifunctional phosphoglucose/phosphomannose isomerase GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 VMUT_0737 e2ac7ed840fdda2ee2d24f9f1da50337 338 SUPERFAMILY SSF53697 50 323 5.5E-38 T 23-10-2018 VMUT_0737 e2ac7ed840fdda2ee2d24f9f1da50337 338 Pfam PF01380 SIS domain 88 121 5.9E-6 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 VMUT_0737 e2ac7ed840fdda2ee2d24f9f1da50337 338 Gene3D G3DSA:3.40.50.10490 16 172 6.9E-35 T 23-10-2018 VMUT_0737 e2ac7ed840fdda2ee2d24f9f1da50337 338 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 186 329 1.1E-30 T 23-10-2018 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 VMUT_0737 e2ac7ed840fdda2ee2d24f9f1da50337 338 Gene3D G3DSA:3.40.50.10490 187 331 3.2E-28 T 23-10-2018 VMUT_0773 20b497bd8bd631be4c84737434509eb3 319 Pfam PF00953 Glycosyl transferase family 4 75 225 7.6E-25 T 23-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 VMUT_1134 72d559eea4215742e6ed61d54351cf8d 97 SUPERFAMILY SSF54862 25 96 5.02E-19 T 23-10-2018 VMUT_1134 72d559eea4215742e6ed61d54351cf8d 97 Gene3D G3DSA:3.30.70.20 9 92 3.2E-15 T 23-10-2018 VMUT_1134 72d559eea4215742e6ed61d54351cf8d 97 PIRSF PIRSF036548 3 97 2.7E-34 T 23-10-2018 IPR012206 Ferredoxin-like, FixX GO:0005506 VMUT_1134 72d559eea4215742e6ed61d54351cf8d 97 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 66 77 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_1134 72d559eea4215742e6ed61d54351cf8d 97 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 16 94 5.7E-8 T 23-10-2018 VMUT_2208 7aa48fc969af6319b3af251a7bfc5341 158 SUPERFAMILY SSF54637 6 147 6.51E-42 T 23-10-2018 IPR029069 HotDog domain superfamily VMUT_2208 7aa48fc969af6319b3af251a7bfc5341 158 Pfam PF01575 MaoC like domain 14 119 2.2E-25 T 23-10-2018 IPR002539 MaoC-like dehydratase domain VMUT_2208 7aa48fc969af6319b3af251a7bfc5341 158 Gene3D G3DSA:3.10.129.10 6 156 6.6E-48 T 23-10-2018 VMUT_1411 fe9d172808f0f3fbac958b9831b5bbe5 477 SUPERFAMILY SSF101960 42 470 3.53E-120 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily VMUT_1411 fe9d172808f0f3fbac958b9831b5bbe5 477 Pfam PF01458 Uncharacterized protein family (UPF0051) 221 446 1.3E-63 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 VMUT_1411 fe9d172808f0f3fbac958b9831b5bbe5 477 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 35 466 1.2E-186 T 23-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 VMUT_0935 9d10f1621f5cc96606c8898fd1c5fd62 892 TIGRFAM TIGR00422 valS: valine--tRNA ligase 97 853 2.1E-196 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 VMUT_0935 9d10f1621f5cc96606c8898fd1c5fd62 892 SUPERFAMILY SSF47323 674 889 2.06E-40 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_0935 9d10f1621f5cc96606c8898fd1c5fd62 892 PRINTS PR00986 Valyl-tRNA synthetase signature 428 441 4.9E-11 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 VMUT_0935 9d10f1621f5cc96606c8898fd1c5fd62 892 PRINTS PR00986 Valyl-tRNA synthetase signature 313 330 4.9E-11 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 VMUT_0935 9d10f1621f5cc96606c8898fd1c5fd62 892 PRINTS PR00986 Valyl-tRNA synthetase signature 540 561 4.9E-11 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 VMUT_0935 9d10f1621f5cc96606c8898fd1c5fd62 892 PRINTS PR00986 Valyl-tRNA synthetase signature 573 591 4.9E-11 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 VMUT_0935 9d10f1621f5cc96606c8898fd1c5fd62 892 PRINTS PR00986 Valyl-tRNA synthetase signature 123 134 4.9E-11 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 VMUT_0935 9d10f1621f5cc96606c8898fd1c5fd62 892 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 102 659 1.2E-116 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_0935 9d10f1621f5cc96606c8898fd1c5fd62 892 Gene3D G3DSA:1.10.730.10 99 808 1.3E-199 T 23-10-2018 VMUT_0935 9d10f1621f5cc96606c8898fd1c5fd62 892 Gene3D G3DSA:3.90.740.10 258 424 1.3E-199 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 VMUT_0935 9d10f1621f5cc96606c8898fd1c5fd62 892 SUPERFAMILY SSF50677 274 424 2.35E-41 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 VMUT_0935 9d10f1621f5cc96606c8898fd1c5fd62 892 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 130 141 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_0935 9d10f1621f5cc96606c8898fd1c5fd62 892 Gene3D G3DSA:3.40.50.620 109 622 1.3E-199 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_0935 9d10f1621f5cc96606c8898fd1c5fd62 892 SUPERFAMILY SSF52374 101 667 1.66E-110 T 23-10-2018 VMUT_0935 9d10f1621f5cc96606c8898fd1c5fd62 892 Pfam PF08264 Anticodon-binding domain of tRNA 699 843 9.7E-28 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 VMUT_0495 2822b33f21bca6009062d7cda28ab1f9 286 SUPERFAMILY SSF103501 58 255 4.32E-14 T 23-10-2018 IPR036197 NarG-like superfamily VMUT_1611 fc33de48df5fa51341925e0da4a0c8fe 450 Pfam PF07690 Major Facilitator Superfamily 1 382 3.3E-47 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_1611 fc33de48df5fa51341925e0da4a0c8fe 450 Gene3D G3DSA:1.20.1250.20 1 172 3.4E-40 T 23-10-2018 VMUT_1611 fc33de48df5fa51341925e0da4a0c8fe 450 Gene3D G3DSA:1.20.1250.20 228 439 3.3E-16 T 23-10-2018 VMUT_1611 fc33de48df5fa51341925e0da4a0c8fe 450 SUPERFAMILY SSF103473 1 438 7.98E-60 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_0398 8346a75b3cce0f2a975f129dccc5ff61 404 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 274 373 6.8E-24 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II VMUT_0398 8346a75b3cce0f2a975f129dccc5ff61 404 SUPERFAMILY SSF52922 265 394 5.57E-27 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VMUT_0398 8346a75b3cce0f2a975f129dccc5ff61 404 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 24 250 1.7E-63 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 VMUT_0398 8346a75b3cce0f2a975f129dccc5ff61 404 SUPERFAMILY SSF52518 12 262 1.4E-61 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold VMUT_0398 8346a75b3cce0f2a975f129dccc5ff61 404 Gene3D G3DSA:3.40.50.920 265 399 7.2E-28 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VMUT_0398 8346a75b3cce0f2a975f129dccc5ff61 404 Gene3D G3DSA:3.40.50.970 10 263 1.1E-89 T 23-10-2018 VMUT_0198 32541caf373d0810f04c15b274b1b3cb 185 Pfam PF13384 Homeodomain-like domain 13 45 3.3E-7 T 23-10-2018 VMUT_0198 32541caf373d0810f04c15b274b1b3cb 185 Gene3D G3DSA:1.10.10.10 1 87 4.7E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_0198 32541caf373d0810f04c15b274b1b3cb 185 SUPERFAMILY SSF88659 3 50 1.05E-7 T 23-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like VMUT_2023 a3caf4f5c3f257a9bd61372ba4761e20 431 Gene3D G3DSA:1.20.1250.20 29 223 8.0E-25 T 23-10-2018 VMUT_2023 a3caf4f5c3f257a9bd61372ba4761e20 431 SUPERFAMILY SSF103473 28 422 1.31E-47 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_2023 a3caf4f5c3f257a9bd61372ba4761e20 431 Gene3D G3DSA:1.20.1250.20 244 428 1.2E-14 T 23-10-2018 VMUT_2023 a3caf4f5c3f257a9bd61372ba4761e20 431 Pfam PF07690 Major Facilitator Superfamily 47 381 2.5E-26 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_0759 7b99fa290f255959ab02d8fcab036cb9 173 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 48 62 1.5E-23 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family VMUT_0759 7b99fa290f255959ab02d8fcab036cb9 173 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 83 93 1.5E-23 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family VMUT_0759 7b99fa290f255959ab02d8fcab036cb9 173 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 93 107 1.5E-23 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family VMUT_0759 7b99fa290f255959ab02d8fcab036cb9 173 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 67 80 1.5E-23 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family VMUT_0759 7b99fa290f255959ab02d8fcab036cb9 173 Hamap MF_00326 50S ribosomal protein L7Ae [rpl7ae]. 19 139 32.737 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_0759 7b99fa290f255959ab02d8fcab036cb9 173 SUPERFAMILY SSF55315 22 138 9.13E-37 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like VMUT_0759 7b99fa290f255959ab02d8fcab036cb9 173 TIGRFAM TIGR03677 eL8_ribo: ribosomal protein eL8 22 138 1.5E-51 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_0759 7b99fa290f255959ab02d8fcab036cb9 173 Gene3D G3DSA:3.30.1330.30 17 143 9.8E-40 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like VMUT_0759 7b99fa290f255959ab02d8fcab036cb9 173 ProSitePatterns PS01082 Ribosomal protein L7Ae signature. 86 103 - T 23-10-2018 IPR004037 Ribosomal protein L7Ae conserved site GO:0042254|GO:1990904 Reactome: R-HSA-6791226 VMUT_0759 7b99fa290f255959ab02d8fcab036cb9 173 PRINTS PR00884 Ribosomal protein HS6 signature 93 103 8.7E-21 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_0759 7b99fa290f255959ab02d8fcab036cb9 173 PRINTS PR00884 Ribosomal protein HS6 signature 22 33 8.7E-21 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_0759 7b99fa290f255959ab02d8fcab036cb9 173 PRINTS PR00884 Ribosomal protein HS6 signature 66 77 8.7E-21 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_0759 7b99fa290f255959ab02d8fcab036cb9 173 PRINTS PR00884 Ribosomal protein HS6 signature 56 66 8.7E-21 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_0759 7b99fa290f255959ab02d8fcab036cb9 173 PRINTS PR00884 Ribosomal protein HS6 signature 107 123 8.7E-21 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_0759 7b99fa290f255959ab02d8fcab036cb9 173 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 34 124 2.2E-30 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 VMUT_1751 50319c6bc1e40e369dd90694a960b37f 295 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 13 292 4.4E-76 T 23-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 VMUT_1751 50319c6bc1e40e369dd90694a960b37f 295 Gene3D G3DSA:3.40.50.2020 157 282 7.8E-32 T 23-10-2018 VMUT_1751 50319c6bc1e40e369dd90694a960b37f 295 SMART SM01400 4 121 2.4E-25 T 23-10-2018 VMUT_1751 50319c6bc1e40e369dd90694a960b37f 295 Gene3D G3DSA:3.40.50.2020 6 156 3.1E-36 T 23-10-2018 VMUT_1751 50319c6bc1e40e369dd90694a960b37f 295 SUPERFAMILY SSF53271 73 280 3.57E-35 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like VMUT_1751 50319c6bc1e40e369dd90694a960b37f 295 Pfam PF00156 Phosphoribosyl transferase domain 156 273 6.6E-17 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 VMUT_1751 50319c6bc1e40e369dd90694a960b37f 295 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 7 121 1.7E-18 T 23-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 VMUT_2246 6b134b3ce98137981278d57018a3fba5 262 Gene3D G3DSA:3.40.50.1000 16 257 2.0E-74 T 23-10-2018 IPR023214 HAD superfamily VMUT_2246 6b134b3ce98137981278d57018a3fba5 262 PIRSF PIRSF000915 1 262 3.2E-52 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA VMUT_2246 6b134b3ce98137981278d57018a3fba5 262 Pfam PF13344 Haloacid dehalogenase-like hydrolase 14 113 9.5E-20 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA VMUT_2246 6b134b3ce98137981278d57018a3fba5 262 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 14 236 1.8E-39 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA VMUT_2246 6b134b3ce98137981278d57018a3fba5 262 Gene3D G3DSA:3.40.50.1000 80 186 2.0E-74 T 23-10-2018 IPR023214 HAD superfamily VMUT_2246 6b134b3ce98137981278d57018a3fba5 262 SUPERFAMILY SSF56784 12 261 1.44E-60 T 23-10-2018 IPR036412 HAD-like superfamily VMUT_2246 6b134b3ce98137981278d57018a3fba5 262 Pfam PF13242 HAD-hyrolase-like 187 259 1.0E-19 T 23-10-2018 VMUT_1845 9d4781d3dc277246c09587f63f9a1b89 169 Pfam PF13545 Crp-like helix-turn-helix domain 41 86 2.6E-7 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VMUT_1845 9d4781d3dc277246c09587f63f9a1b89 169 SMART SM00419 37 85 5.0E-4 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VMUT_1845 9d4781d3dc277246c09587f63f9a1b89 169 SUPERFAMILY SSF54909 97 167 1.88E-7 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel VMUT_1845 9d4781d3dc277246c09587f63f9a1b89 169 Gene3D G3DSA:1.10.10.10 19 92 7.4E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_1845 9d4781d3dc277246c09587f63f9a1b89 169 Pfam PF01037 Lrp/AsnC ligand binding domain 100 166 5.0E-9 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain VMUT_1845 9d4781d3dc277246c09587f63f9a1b89 169 SUPERFAMILY SSF46785 19 92 9.93E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_1845 9d4781d3dc277246c09587f63f9a1b89 169 Gene3D G3DSA:3.30.70.920 96 162 1.0E-8 T 23-10-2018 VMUT_1875 816bc202e8c3cad9415bea07c1e82c7a 252 Pfam PF00149 Calcineurin-like phosphoesterase 4 193 9.3E-12 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 VMUT_1875 816bc202e8c3cad9415bea07c1e82c7a 252 SUPERFAMILY SSF56300 2 225 3.8E-27 T 23-10-2018 VMUT_1875 816bc202e8c3cad9415bea07c1e82c7a 252 Gene3D G3DSA:3.60.21.10 3 239 1.5E-12 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like VMUT_1421 404d4491c11c9db2cfb936f0c82524ca 413 SUPERFAMILY SSF53686 32 410 1.96E-103 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme VMUT_1421 404d4491c11c9db2cfb936f0c82524ca 413 PIRSF PIRSF500824 1 412 1.0E-179 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 VMUT_1421 404d4491c11c9db2cfb936f0c82524ca 413 Gene3D G3DSA:3.40.50.1100 3 406 7.2E-154 T 23-10-2018 VMUT_1421 404d4491c11c9db2cfb936f0c82524ca 413 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 67 400 8.5E-47 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme VMUT_1421 404d4491c11c9db2cfb936f0c82524ca 413 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 95 109 - T 23-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 VMUT_1421 404d4491c11c9db2cfb936f0c82524ca 413 Gene3D G3DSA:3.40.50.1100 4 228 7.2E-154 T 23-10-2018 VMUT_1421 404d4491c11c9db2cfb936f0c82524ca 413 PIRSF PIRSF001413 1 413 5.0E-136 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 VMUT_1421 404d4491c11c9db2cfb936f0c82524ca 413 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 3 411 1.5E-180 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 VMUT_1421 404d4491c11c9db2cfb936f0c82524ca 413 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 11 413 38.798 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 VMUT_0285 4b8e48bd1f10d0a736501a231ee68b40 251 Pfam PF01939 Endonuclease NucS 37 249 5.5E-57 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 VMUT_0285 4b8e48bd1f10d0a736501a231ee68b40 251 Hamap MF_00722 Endonuclease NucS [nucS]. 38 251 33.628 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 VMUT_0285 4b8e48bd1f10d0a736501a231ee68b40 251 Gene3D G3DSA:3.40.1350.10 135 248 2.6E-40 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 VMUT_0285 4b8e48bd1f10d0a736501a231ee68b40 251 Gene3D G3DSA:2.70.180.20 14 131 5.9E-25 T 23-10-2018 VMUT_1043 a9872891b4132bf28b93cc2a2951d867 395 Pfam PF13439 Glycosyltransferase Family 4 15 202 9.0E-7 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 VMUT_1043 a9872891b4132bf28b93cc2a2951d867 395 Gene3D G3DSA:3.40.50.2000 212 372 1.8E-15 T 23-10-2018 VMUT_1043 a9872891b4132bf28b93cc2a2951d867 395 SUPERFAMILY SSF53756 2 372 5.21E-39 T 23-10-2018 VMUT_1043 a9872891b4132bf28b93cc2a2951d867 395 Pfam PF13692 Glycosyl transferases group 1 218 352 3.7E-9 T 23-10-2018 VMUT_1176 484c46a808a0ed98ab158b2764327773 425 Gene3D G3DSA:1.20.1740.10 2 421 1.6E-25 T 23-10-2018 VMUT_1176 484c46a808a0ed98ab158b2764327773 425 Pfam PF00324 Amino acid permease 7 412 3.3E-23 T 23-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 VMUT_1176 484c46a808a0ed98ab158b2764327773 425 PIRSF PIRSF006060 3 422 5.9E-42 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_0274 541eb48b2829c362da07b7eb6be33c91 471 SUPERFAMILY SSF52317 25 188 5.18E-17 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like VMUT_0274 541eb48b2829c362da07b7eb6be33c91 471 Gene3D G3DSA:3.40.50.300 238 431 3.5E-14 T 23-10-2018 VMUT_0274 541eb48b2829c362da07b7eb6be33c91 471 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 240 425 7.1E-7 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain VMUT_0274 541eb48b2829c362da07b7eb6be33c91 471 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 25 194 3.1E-10 T 23-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 VMUT_0274 541eb48b2829c362da07b7eb6be33c91 471 Gene3D G3DSA:3.40.50.880 1 209 2.7E-11 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like VMUT_0274 541eb48b2829c362da07b7eb6be33c91 471 SUPERFAMILY SSF52540 235 424 1.29E-16 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_2225 29684621017e13e9d4907b58a5a8877a 271 Gene3D G3DSA:2.40.50.140 1 82 1.2E-22 T 23-10-2018 VMUT_2225 29684621017e13e9d4907b58a5a8877a 271 SUPERFAMILY SSF50249 2 93 4.11E-15 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold VMUT_2225 29684621017e13e9d4907b58a5a8877a 271 PIRSF PIRSF002158 1 248 5.4E-63 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_2225 29684621017e13e9d4907b58a5a8877a 271 SMART SM01382 92 223 2.5E-61 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 VMUT_2225 29684621017e13e9d4907b58a5a8877a 271 Hamap MF_01320_A 50S ribosomal protein L2 [rplB]. 1 238 38.216 T 23-10-2018 IPR023672 Ribosomal protein L2, archaeal-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_2225 29684621017e13e9d4907b58a5a8877a 271 SUPERFAMILY SSF50104 95 237 3.55E-47 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily VMUT_2225 29684621017e13e9d4907b58a5a8877a 271 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 11 85 1.0E-12 T 23-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_2225 29684621017e13e9d4907b58a5a8877a 271 Gene3D G3DSA:2.30.30.30 86 163 1.2E-28 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 VMUT_2225 29684621017e13e9d4907b58a5a8877a 271 Gene3D G3DSA:4.10.950.10 164 240 1.8E-27 T 23-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_2225 29684621017e13e9d4907b58a5a8877a 271 SMART SM01383 11 86 1.7E-23 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_2225 29684621017e13e9d4907b58a5a8877a 271 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 94 222 4.9E-43 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 VMUT_1840 8830b4989e248fee6e254e61fb21864d 321 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 128 156 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VMUT_1840 8830b4989e248fee6e254e61fb21864d 321 Gene3D G3DSA:3.90.25.10 173 301 3.8E-95 T 23-10-2018 VMUT_1840 8830b4989e248fee6e254e61fb21864d 321 Gene3D G3DSA:3.40.50.720 2 236 3.8E-95 T 23-10-2018 VMUT_1840 8830b4989e248fee6e254e61fb21864d 321 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 304 1.0E-52 T 23-10-2018 IPR016040 NAD(P)-binding domain VMUT_1840 8830b4989e248fee6e254e61fb21864d 321 SUPERFAMILY SSF51735 1 311 1.49E-82 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1760 ca65a7f5beac9d9c7fb9c9f1e0b9ad74 203 Gene3D G3DSA:3.30.160.770 9 113 3.5E-40 T 23-10-2018 VMUT_1760 ca65a7f5beac9d9c7fb9c9f1e0b9ad74 203 Pfam PF03719 Ribosomal protein S5, C-terminal domain 137 201 3.9E-22 T 23-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 VMUT_1760 ca65a7f5beac9d9c7fb9c9f1e0b9ad74 203 Gene3D G3DSA:3.30.230.10 114 203 9.4E-32 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup VMUT_1760 ca65a7f5beac9d9c7fb9c9f1e0b9ad74 203 SUPERFAMILY SSF54768 45 116 2.72E-19 T 23-10-2018 VMUT_1760 ca65a7f5beac9d9c7fb9c9f1e0b9ad74 203 Pfam PF00333 Ribosomal protein S5, N-terminal domain 51 115 7.7E-23 T 23-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 VMUT_1760 ca65a7f5beac9d9c7fb9c9f1e0b9ad74 203 SUPERFAMILY SSF54211 129 201 8.85E-21 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VMUT_1760 ca65a7f5beac9d9c7fb9c9f1e0b9ad74 203 TIGRFAM TIGR01020 uS5_euk_arch: ribosomal protein uS5 6 200 1.4E-93 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1760 ca65a7f5beac9d9c7fb9c9f1e0b9ad74 203 Hamap MF_01307_A 30S ribosomal protein S5 [rpsE]. 3 203 45.987 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1760 ca65a7f5beac9d9c7fb9c9f1e0b9ad74 203 ProSitePatterns PS00585 Ribosomal protein S5 signature. 68 100 - T 23-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site VMUT_1558 eebaedd29f30d1d98661197f8df38094 172 SUPERFAMILY SSF47741 98 166 1.11E-34 T 23-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily VMUT_1558 eebaedd29f30d1d98661197f8df38094 172 SUPERFAMILY SSF54292 2 101 4.19E-25 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VMUT_1558 eebaedd29f30d1d98661197f8df38094 172 Pfam PF01799 [2Fe-2S] binding domain 87 160 7.9E-33 T 23-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 VMUT_1558 eebaedd29f30d1d98661197f8df38094 172 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 20 70 7.4E-6 T 23-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VMUT_1558 eebaedd29f30d1d98661197f8df38094 172 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 53 61 - T 23-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VMUT_1558 eebaedd29f30d1d98661197f8df38094 172 Gene3D G3DSA:1.10.150.120 91 171 3.4E-36 T 23-10-2018 VMUT_1558 eebaedd29f30d1d98661197f8df38094 172 Gene3D G3DSA:3.10.20.30 7 90 1.0E-29 T 23-10-2018 IPR012675 Beta-grasp domain superfamily VMUT_1832 87c92fa925c2769f1ebd55b87d0ec1d3 508 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 17 502 7.7E-115 T 23-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 VMUT_1832 87c92fa925c2769f1ebd55b87d0ec1d3 508 Gene3D G3DSA:3.40.50.300 15 246 4.0E-40 T 23-10-2018 VMUT_1832 87c92fa925c2769f1ebd55b87d0ec1d3 508 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 16 250 2.8E-19 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain VMUT_1832 87c92fa925c2769f1ebd55b87d0ec1d3 508 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 508 126.167 T 23-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 VMUT_1832 87c92fa925c2769f1ebd55b87d0ec1d3 508 SUPERFAMILY SSF52540 16 251 1.63E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1832 87c92fa925c2769f1ebd55b87d0ec1d3 508 SUPERFAMILY SSF52317 262 461 1.01E-27 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like VMUT_1832 87c92fa925c2769f1ebd55b87d0ec1d3 508 Gene3D G3DSA:3.40.50.880 262 413 1.5E-16 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like VMUT_1832 87c92fa925c2769f1ebd55b87d0ec1d3 508 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 263 448 3.0E-36 T 23-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 VMUT_0955 fccfe5765900539926f6bc7ff18ec0c0 618 Gene3D G3DSA:1.10.569.10 246 432 4.2E-107 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 VMUT_0955 fccfe5765900539926f6bc7ff18ec0c0 618 SUPERFAMILY SSF48310 218 614 3.66E-117 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_0955 fccfe5765900539926f6bc7ff18ec0c0 618 Gene3D G3DSA:3.60.9.10 2 213 1.3E-71 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily VMUT_0955 fccfe5765900539926f6bc7ff18ec0c0 618 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 5 209 1.7E-68 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_0955 fccfe5765900539926f6bc7ff18ec0c0 618 Gene3D G3DSA:1.10.599.10 244 611 4.2E-107 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 VMUT_0955 fccfe5765900539926f6bc7ff18ec0c0 618 SMART SM00790 4 210 8.8E-103 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_0955 fccfe5765900539926f6bc7ff18ec0c0 618 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 225 611 4.8E-121 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_0955 fccfe5765900539926f6bc7ff18ec0c0 618 SUPERFAMILY SSF56228 3 211 7.32E-64 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily VMUT_1644 8a35d3eb4a1d03d89136a28f259102b3 197 Pfam PF03692 Putative zinc- or iron-chelating domain 12 116 1.1E-9 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein VMUT_1529 f1101444c76edc00f586748b586dd2ca 339 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 154 319 1.8E-22 T 23-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 VMUT_1529 f1101444c76edc00f586748b586dd2ca 339 Gene3D G3DSA:3.30.360.10 145 316 4.5E-105 T 23-10-2018 VMUT_1529 f1101444c76edc00f586748b586dd2ca 339 SUPERFAMILY SSF55347 143 321 9.52E-32 T 23-10-2018 VMUT_1529 f1101444c76edc00f586748b586dd2ca 339 SMART SM00859 5 131 5.6E-28 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 VMUT_1529 f1101444c76edc00f586748b586dd2ca 339 PIRSF PIRSF000148 3 339 2.0E-76 T 23-10-2018 VMUT_1529 f1101444c76edc00f586748b586dd2ca 339 SUPERFAMILY SSF51735 4 170 3.01E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1529 f1101444c76edc00f586748b586dd2ca 339 Gene3D G3DSA:3.40.50.720 4 331 4.5E-105 T 23-10-2018 VMUT_1529 f1101444c76edc00f586748b586dd2ca 339 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 128 1.3E-28 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 VMUT_1529 f1101444c76edc00f586748b586dd2ca 339 TIGRFAM TIGR00978 asd_EA: aspartate-semialdehyde dehydrogenase 4 334 2.1E-120 T 23-10-2018 IPR005676 Aspartate-semialdehyde dehydrogenase, peptidoglycan lacking GO:0050661|GO:0055114 VMUT_0754 d5b4c96ed1cfac16829d85e2744c9daa 120 Pfam PF11494 Ta0938 38 101 1.9E-10 T 23-10-2018 IPR021585 Ta0938 VMUT_1544 60b657fda24d74c604e76dae9b2944b6 452 PRINTS PR00145 Argininosuccinate lyase family signature 189 205 1.6E-21 T 23-10-2018 VMUT_1544 60b657fda24d74c604e76dae9b2944b6 452 PRINTS PR00145 Argininosuccinate lyase family signature 271 287 1.6E-21 T 23-10-2018 VMUT_1544 60b657fda24d74c604e76dae9b2944b6 452 PRINTS PR00145 Argininosuccinate lyase family signature 306 325 1.6E-21 T 23-10-2018 VMUT_1544 60b657fda24d74c604e76dae9b2944b6 452 PRINTS PR00145 Argininosuccinate lyase family signature 227 251 1.6E-21 T 23-10-2018 VMUT_1544 60b657fda24d74c604e76dae9b2944b6 452 PRINTS PR00145 Argininosuccinate lyase family signature 97 119 1.6E-21 T 23-10-2018 VMUT_1544 60b657fda24d74c604e76dae9b2944b6 452 PRINTS PR00145 Argininosuccinate lyase family signature 138 158 1.6E-21 T 23-10-2018 VMUT_1544 60b657fda24d74c604e76dae9b2944b6 452 SUPERFAMILY SSF48557 15 403 2.04E-76 T 23-10-2018 IPR008948 L-Aspartase-like GO:0003824 VMUT_1544 60b657fda24d74c604e76dae9b2944b6 452 PRINTS PR00149 Fumarate lyase superfamily signature 98 116 2.4E-12 T 23-10-2018 IPR000362 Fumarate lyase family VMUT_1544 60b657fda24d74c604e76dae9b2944b6 452 PRINTS PR00149 Fumarate lyase superfamily signature 143 161 2.4E-12 T 23-10-2018 IPR000362 Fumarate lyase family VMUT_1544 60b657fda24d74c604e76dae9b2944b6 452 PRINTS PR00149 Fumarate lyase superfamily signature 271 287 2.4E-12 T 23-10-2018 IPR000362 Fumarate lyase family VMUT_1544 60b657fda24d74c604e76dae9b2944b6 452 Gene3D G3DSA:1.10.40.30 356 399 4.6E-86 T 23-10-2018 VMUT_1544 60b657fda24d74c604e76dae9b2944b6 452 Gene3D G3DSA:1.20.200.10 115 355 4.6E-86 T 23-10-2018 VMUT_1544 60b657fda24d74c604e76dae9b2944b6 452 Pfam PF00206 Lyase 18 296 2.8E-32 T 23-10-2018 IPR022761 Fumarate lyase, N-terminal VMUT_1544 60b657fda24d74c604e76dae9b2944b6 452 Gene3D G3DSA:1.10.275.10 27 225 4.6E-86 T 23-10-2018 IPR024083 Fumarase/histidase, N-terminal VMUT_1579 1b42617ba6a519ceb266363a6c5c99b0 283 Gene3D G3DSA:3.40.830.10 1 283 6.0E-63 T 23-10-2018 VMUT_1579 1b42617ba6a519ceb266363a6c5c99b0 283 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 2 281 5.0E-92 T 23-10-2018 VMUT_1579 1b42617ba6a519ceb266363a6c5c99b0 283 Hamap MF_00055 MEMO1 family protein . 1 282 57.319 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 VMUT_1579 1b42617ba6a519ceb266363a6c5c99b0 283 Pfam PF01875 Memo-like protein 4 279 6.2E-78 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 VMUT_2194 a2f4597edbd0b5aec8f09ec876da0993 307 Pfam PF07859 alpha/beta hydrolase fold 74 281 2.5E-74 T 23-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 VMUT_2194 a2f4597edbd0b5aec8f09ec876da0993 307 SUPERFAMILY SSF53474 16 303 1.94E-76 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold VMUT_2194 a2f4597edbd0b5aec8f09ec876da0993 307 Gene3D G3DSA:3.40.50.1820 1 306 6.0E-92 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold VMUT_0108 6fd169dc4eabb9fcfa5bbe6d4e9b559a 71 Gene3D G3DSA:2.40.50.140 1 46 4.0E-19 T 23-10-2018 VMUT_0108 6fd169dc4eabb9fcfa5bbe6d4e9b559a 71 Pfam PF01938 TRAM domain 4 45 1.8E-11 T 23-10-2018 IPR002792 TRAM domain VMUT_0108 6fd169dc4eabb9fcfa5bbe6d4e9b559a 71 SUPERFAMILY SSF50249 4 46 3.77E-13 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold VMUT_1720 c5af29d84124e492cb7893dfc9e6721f 402 Gene3D G3DSA:3.40.50.2000 208 384 3.9E-30 T 23-10-2018 VMUT_1720 c5af29d84124e492cb7893dfc9e6721f 402 SUPERFAMILY SSF53756 3 401 3.84E-48 T 23-10-2018 VMUT_1720 c5af29d84124e492cb7893dfc9e6721f 402 Pfam PF00534 Glycosyl transferases group 1 211 375 2.2E-25 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 VMUT_2190 2e95856425637df07839383e12932db4 676 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 109 571 6.1E-65 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain VMUT_2190 2e95856425637df07839383e12932db4 676 SUPERFAMILY SSF53850 59 656 5.61E-96 T 23-10-2018 VMUT_2190 2e95856425637df07839383e12932db4 676 PIRSF PIRSF002741 15 178 9.1E-16 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 VMUT_2190 2e95856425637df07839383e12932db4 676 PIRSF PIRSF002741 222 658 1.8E-48 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 VMUT_2190 2e95856425637df07839383e12932db4 676 Gene3D G3DSA:3.10.105.10 394 628 1.8E-41 T 23-10-2018 VMUT_0497 ccfec212587dccdd95a69869ce60708e 472 Gene3D G3DSA:1.10.1060.10 33 173 3.5E-5 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VMUT_0497 ccfec212587dccdd95a69869ce60708e 472 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 143 154 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_0497 ccfec212587dccdd95a69869ce60708e 472 Pfam PF02754 Cysteine-rich domain 355 442 1.4E-8 T 23-10-2018 IPR004017 Cysteine-rich domain VMUT_0497 ccfec212587dccdd95a69869ce60708e 472 Pfam PF13183 4Fe-4S dicluster domain 72 157 3.3E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_0497 ccfec212587dccdd95a69869ce60708e 472 SUPERFAMILY SSF46548 62 172 2.79E-18 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VMUT_0497 ccfec212587dccdd95a69869ce60708e 472 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 74 85 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_1837 4d0914fa8b039d3880a6e41929fc148e 327 Gene3D G3DSA:3.40.1190.20 7 320 2.5E-98 T 23-10-2018 IPR029056 Ribokinase-like VMUT_1837 4d0914fa8b039d3880a6e41929fc148e 327 Pfam PF00294 pfkB family carbohydrate kinase 7 308 2.0E-52 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB VMUT_1837 4d0914fa8b039d3880a6e41929fc148e 327 SUPERFAMILY SSF53613 6 317 1.87E-83 T 23-10-2018 IPR029056 Ribokinase-like VMUT_0010 e87c565d26a24245ba766a28d8940b26 473 Gene3D G3DSA:1.20.1740.10 28 468 1.1E-42 T 23-10-2018 VMUT_0010 e87c565d26a24245ba766a28d8940b26 473 Pfam PF00324 Amino acid permease 44 446 1.3E-30 T 23-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 VMUT_0010 e87c565d26a24245ba766a28d8940b26 473 PIRSF PIRSF006060 1 471 1.0E-51 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_0598 8428316d7d0883703cf0d8152ae29758 189 Pfam PF01944 Stage II sporulation protein M 24 175 1.3E-10 T 23-10-2018 IPR002798 Stage II sporulation protein M-like VMUT_0585 c3bf2200e6106dd85c226ddb40130c6c 266 Gene3D G3DSA:3.90.226.10 16 266 8.1E-76 T 23-10-2018 VMUT_0585 c3bf2200e6106dd85c226ddb40130c6c 266 Pfam PF00378 Enoyl-CoA hydratase/isomerase 21 264 4.9E-55 T 23-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VMUT_0585 c3bf2200e6106dd85c226ddb40130c6c 266 SUPERFAMILY SSF52096 16 265 5.16E-75 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VMUT_0585 c3bf2200e6106dd85c226ddb40130c6c 266 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 107 127 - T 23-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 VMUT_1430 33a0ffbffb54af7f8559c8d7353bca9d 348 SUPERFAMILY SSF56796 39 328 7.72E-74 T 23-10-2018 VMUT_1430 33a0ffbffb54af7f8559c8d7353bca9d 348 PIRSF PIRSF001455 28 344 3.3E-95 T 23-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 VMUT_1430 33a0ffbffb54af7f8559c8d7353bca9d 348 Pfam PF01761 3-dehydroquinate synthase 55 310 2.8E-79 T 23-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 VMUT_1430 33a0ffbffb54af7f8559c8d7353bca9d 348 Gene3D G3DSA:3.40.50.1970 8 159 3.1E-40 T 23-10-2018 VMUT_1430 33a0ffbffb54af7f8559c8d7353bca9d 348 Gene3D G3DSA:1.20.1090.10 160 341 7.5E-44 T 23-10-2018 VMUT_0388 d7991ec41882f1a1cfb06dc0f02d0081 351 PIRSF PIRSF001123 1 349 8.6E-107 T 23-10-2018 IPR008007 Peptidase M42 VMUT_0388 d7991ec41882f1a1cfb06dc0f02d0081 351 SUPERFAMILY SSF53187 3 339 7.07E-58 T 23-10-2018 VMUT_0388 d7991ec41882f1a1cfb06dc0f02d0081 351 Gene3D G3DSA:3.40.630.10 5 331 8.7E-111 T 23-10-2018 VMUT_0388 d7991ec41882f1a1cfb06dc0f02d0081 351 SUPERFAMILY SSF101821 66 170 2.29E-20 T 23-10-2018 VMUT_0388 d7991ec41882f1a1cfb06dc0f02d0081 351 Gene3D G3DSA:2.40.30.40 65 154 8.7E-111 T 23-10-2018 IPR023367 Peptidase M42, domain 2 VMUT_0388 d7991ec41882f1a1cfb06dc0f02d0081 351 Pfam PF05343 M42 glutamyl aminopeptidase 43 331 1.2E-87 T 23-10-2018 IPR008007 Peptidase M42 VMUT_0672 803f2f14b111f1eae2cb48b4cb170a0e 241 Pfam PF01904 Protein of unknown function DUF72 12 236 9.3E-31 T 23-10-2018 IPR002763 Protein of unknown function DUF72 VMUT_0672 803f2f14b111f1eae2cb48b4cb170a0e 241 SUPERFAMILY SSF117396 1 240 5.23E-42 T 23-10-2018 IPR036520 UPF0759 superfamily VMUT_0672 803f2f14b111f1eae2cb48b4cb170a0e 241 Gene3D G3DSA:3.20.20.410 1 241 1.9E-34 T 23-10-2018 IPR036520 UPF0759 superfamily VMUT_1972 2845849759964f69afa3ad67345c63f3 330 Pfam PF01180 Dihydroorotate dehydrogenase 41 315 1.0E-41 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 VMUT_1972 2845849759964f69afa3ad67345c63f3 330 PIRSF PIRSF000164 10 324 1.8E-52 T 23-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 VMUT_1972 2845849759964f69afa3ad67345c63f3 330 Gene3D G3DSA:3.20.20.70 3 325 9.3E-54 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_1972 2845849759964f69afa3ad67345c63f3 330 SUPERFAMILY SSF51395 10 320 5.13E-53 T 23-10-2018 VMUT_1972 2845849759964f69afa3ad67345c63f3 330 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 74 93 - T 23-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 VMUT_0724 b849e8783324b609fe6ecba241d224b6 140 Gene3D G3DSA:3.40.30.10 7 139 1.2E-29 T 23-10-2018 VMUT_0724 b849e8783324b609fe6ecba241d224b6 140 ProSitePatterns PS00194 Thioredoxin family active site. 55 73 - T 23-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 VMUT_0724 b849e8783324b609fe6ecba241d224b6 140 TIGRFAM TIGR01068 thioredoxin: thioredoxin 40 135 8.1E-29 T 23-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 VMUT_0724 b849e8783324b609fe6ecba241d224b6 140 SUPERFAMILY SSF52833 10 138 2.84E-36 T 23-10-2018 IPR036249 Thioredoxin-like superfamily VMUT_0724 b849e8783324b609fe6ecba241d224b6 140 Pfam PF00085 Thioredoxin 37 134 2.7E-23 T 23-10-2018 IPR013766 Thioredoxin domain GO:0045454 VMUT_0724 b849e8783324b609fe6ecba241d224b6 140 PRINTS PR00421 Thioredoxin family signature 54 62 1.0E-6 T 23-10-2018 VMUT_0724 b849e8783324b609fe6ecba241d224b6 140 PRINTS PR00421 Thioredoxin family signature 62 71 1.0E-6 T 23-10-2018 VMUT_0724 b849e8783324b609fe6ecba241d224b6 140 PRINTS PR00421 Thioredoxin family signature 101 112 1.0E-6 T 23-10-2018 VMUT_0724 b849e8783324b609fe6ecba241d224b6 140 PIRSF PIRSF000077 34 137 3.3E-27 T 23-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 VMUT_1680 6665d3a899ca46142d6cf9435d769a66 246 SUPERFAMILY SSF55666 153 239 4.32E-22 T 23-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 VMUT_1680 6665d3a899ca46142d6cf9435d769a66 246 SUPERFAMILY SSF54211 10 180 3.59E-46 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VMUT_1680 6665d3a899ca46142d6cf9435d769a66 246 Pfam PF03725 3' exoribonuclease family, domain 2 157 221 4.0E-14 T 23-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 VMUT_1680 6665d3a899ca46142d6cf9435d769a66 246 Pfam PF01138 3' exoribonuclease family, domain 1 23 153 9.0E-36 T 23-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 VMUT_1680 6665d3a899ca46142d6cf9435d769a66 246 TIGRFAM TIGR02065 ECX1: exosome complex exonuclease 1 10 237 1.1E-105 T 23-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 VMUT_1680 6665d3a899ca46142d6cf9435d769a66 246 Gene3D G3DSA:3.30.230.70 9 241 6.0E-76 T 23-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 VMUT_1680 6665d3a899ca46142d6cf9435d769a66 246 Hamap MF_00591 Exosome complex component Rrp41 [rrp41]. 4 241 57.209 T 23-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 VMUT_1413 39b6ad53647566483c236c6fe7f52298 254 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VMUT_1413 39b6ad53647566483c236c6fe7f52298 254 Pfam PF00005 ABC transporter 19 174 6.5E-22 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_1413 39b6ad53647566483c236c6fe7f52298 254 SUPERFAMILY SSF52540 4 235 1.67E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1413 39b6ad53647566483c236c6fe7f52298 254 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 244 5.9E-74 T 23-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 VMUT_1413 39b6ad53647566483c236c6fe7f52298 254 Gene3D G3DSA:3.40.50.300 2 246 2.3E-53 T 23-10-2018 VMUT_1413 39b6ad53647566483c236c6fe7f52298 254 SMART SM00382 28 224 3.1E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0843 f289f34fd351747f5f2d6cf6333bfefc 376 SUPERFAMILY SSF47240 15 90 8.94E-20 T 23-10-2018 IPR009078 Ferritin-like superfamily VMUT_0843 f289f34fd351747f5f2d6cf6333bfefc 376 Pfam PF04454 Encapsulating protein for peroxidase 128 360 5.9E-31 T 23-10-2018 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 VMUT_0843 f289f34fd351747f5f2d6cf6333bfefc 376 Gene3D G3DSA:1.20.1260.10 4 76 1.9E-10 T 23-10-2018 IPR012347 Ferritin-like VMUT_0843 f289f34fd351747f5f2d6cf6333bfefc 376 Pfam PF02915 Rubrerythrin 24 85 2.8E-8 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 VMUT_0843 f289f34fd351747f5f2d6cf6333bfefc 376 Gene3D G3DSA:3.30.2400.30 127 363 2.1E-31 T 23-10-2018 VMUT_0843 f289f34fd351747f5f2d6cf6333bfefc 376 Gene3D G3DSA:3.30.2320.10 240 369 2.1E-31 T 23-10-2018 VMUT_0607 e54f19bd259058e04d03141096510652 207 SUPERFAMILY SSF117457 4 180 5.89E-62 T 23-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 VMUT_0607 e54f19bd259058e04d03141096510652 207 Pfam PF05683 Fumarase C-terminus 10 181 7.8E-50 T 23-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 VMUT_0607 e54f19bd259058e04d03141096510652 207 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 14 180 2.8E-68 T 23-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 VMUT_0607 e54f19bd259058e04d03141096510652 207 Gene3D G3DSA:3.20.130.10 1 181 2.7E-73 T 23-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 VMUT_0093 40e10add3abbb4249efc92e0eadc47c0 248 PIRSF PIRSF002116 1 243 2.1E-86 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0093 40e10add3abbb4249efc92e0eadc47c0 248 Pfam PF08071 RS4NT (NUC023) domain 2 35 8.6E-13 T 23-10-2018 IPR013843 Ribosomal protein S4e, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0093 40e10add3abbb4249efc92e0eadc47c0 248 Gene3D G3DSA:3.10.290.40 1 114 3.5E-38 T 23-10-2018 VMUT_0093 40e10add3abbb4249efc92e0eadc47c0 248 Hamap MF_00485 30S ribosomal protein S4e [rps4e]. 4 238 40.465 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0093 40e10add3abbb4249efc92e0eadc47c0 248 SUPERFAMILY SSF55174 50 90 1.57E-5 T 23-10-2018 VMUT_0093 40e10add3abbb4249efc92e0eadc47c0 248 Gene3D G3DSA:2.40.50.740 119 174 4.9E-21 T 23-10-2018 IPR038237 Ribosomal protein S4e, central domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0093 40e10add3abbb4249efc92e0eadc47c0 248 Pfam PF00900 Ribosomal family S4e 92 169 2.1E-26 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0093 40e10add3abbb4249efc92e0eadc47c0 248 Pfam PF01479 S4 domain 50 87 5.3E-8 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0093 40e10add3abbb4249efc92e0eadc47c0 248 Gene3D G3DSA:2.30.30.30 176 243 4.3E-9 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 VMUT_0093 40e10add3abbb4249efc92e0eadc47c0 248 ProDom PD002667 RIBOSOMAL RIBONUCLEOPROTEIN RNA-BINDING 40S S4 S4 S4E 30S ISOFORM X 84 173 7.0E-21 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0093 40e10add3abbb4249efc92e0eadc47c0 248 SMART SM00363 39 104 0.0013 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0098 7352679f03df5f5444f9c7439d3b2e64 321 Gene3D G3DSA:3.40.1190.20 1 303 8.0E-72 T 23-10-2018 IPR029056 Ribokinase-like VMUT_0098 7352679f03df5f5444f9c7439d3b2e64 321 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 41 65 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 VMUT_0098 7352679f03df5f5444f9c7439d3b2e64 321 Pfam PF00294 pfkB family carbohydrate kinase 7 292 1.7E-49 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB VMUT_0098 7352679f03df5f5444f9c7439d3b2e64 321 SUPERFAMILY SSF53613 7 302 1.71E-69 T 23-10-2018 IPR029056 Ribokinase-like VMUT_0098 7352679f03df5f5444f9c7439d3b2e64 321 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 247 260 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 VMUT_0098 7352679f03df5f5444f9c7439d3b2e64 321 PRINTS PR00990 Ribokinase signature 9 30 9.6E-17 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 VMUT_0098 7352679f03df5f5444f9c7439d3b2e64 321 PRINTS PR00990 Ribokinase signature 108 121 9.6E-17 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 VMUT_0098 7352679f03df5f5444f9c7439d3b2e64 321 PRINTS PR00990 Ribokinase signature 36 55 9.6E-17 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 VMUT_0098 7352679f03df5f5444f9c7439d3b2e64 321 PRINTS PR00990 Ribokinase signature 218 229 9.6E-17 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 VMUT_0098 7352679f03df5f5444f9c7439d3b2e64 321 PRINTS PR00990 Ribokinase signature 178 193 9.6E-17 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 VMUT_0956 6bb888ca8de50b0ca1004d8687aa1200 174 SMART SM00404 61 165 9.0E-4 T 23-10-2018 IPR003595 Protein-tyrosine phosphatase, catalytic VMUT_0956 6bb888ca8de50b0ca1004d8687aa1200 174 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 107 117 - T 23-10-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 VMUT_0956 6bb888ca8de50b0ca1004d8687aa1200 174 SUPERFAMILY SSF52799 9 164 2.18E-35 T 23-10-2018 IPR029021 Protein-tyrosine phosphatase-like VMUT_0956 6bb888ca8de50b0ca1004d8687aa1200 174 SMART SM00195 35 162 8.0E-10 T 23-10-2018 IPR020422 Dual specificity protein phosphatase domain GO:0006470|GO:0008138 VMUT_0956 6bb888ca8de50b0ca1004d8687aa1200 174 Gene3D G3DSA:3.90.190.10 11 171 4.6E-33 T 23-10-2018 IPR029021 Protein-tyrosine phosphatase-like VMUT_0956 6bb888ca8de50b0ca1004d8687aa1200 174 Pfam PF00782 Dual specificity phosphatase, catalytic domain 64 158 4.0E-19 T 23-10-2018 IPR000340 Dual specificity phosphatase, catalytic domain GO:0008138|GO:0016311 VMUT_1223 11b5c59ca92dd1c8085882318b59ee37 136 PIRSF PIRSF004681 1 136 1.3E-40 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 VMUT_1223 11b5c59ca92dd1c8085882318b59ee37 136 SUPERFAMILY SSF111038 1 134 1.96E-46 T 23-10-2018 IPR035917 YjbQ-like superfamily VMUT_1223 11b5c59ca92dd1c8085882318b59ee37 136 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 7 135 1.5E-42 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 VMUT_1223 11b5c59ca92dd1c8085882318b59ee37 136 Pfam PF01894 Uncharacterised protein family UPF0047 20 131 3.9E-36 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 VMUT_1223 11b5c59ca92dd1c8085882318b59ee37 136 Gene3D G3DSA:2.60.120.460 1 136 1.4E-47 T 23-10-2018 IPR035917 YjbQ-like superfamily VMUT_0235 ecdf96e820a530afb1b7e70be988a774 549 Gene3D G3DSA:3.30.200.20 272 355 7.2E-6 T 23-10-2018 VMUT_0235 ecdf96e820a530afb1b7e70be988a774 549 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 412 424 - T 23-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 VMUT_0235 ecdf96e820a530afb1b7e70be988a774 549 Gene3D G3DSA:1.10.510.10 361 548 4.1E-42 T 23-10-2018 VMUT_0235 ecdf96e820a530afb1b7e70be988a774 549 SUPERFAMILY SSF56112 271 537 2.02E-57 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily VMUT_0235 ecdf96e820a530afb1b7e70be988a774 549 Pfam PF00069 Protein kinase domain 280 535 1.4E-36 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 VMUT_0235 ecdf96e820a530afb1b7e70be988a774 549 SMART SM00220 274 545 3.8E-47 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 VMUT_0903 57276233eb14c4318149dc68fc050132 912 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 61 887 2.6E-192 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 VMUT_0903 57276233eb14c4318149dc68fc050132 912 Gene3D G3DSA:3.30.980.10 594 662 6.7E-19 T 23-10-2018 VMUT_0903 57276233eb14c4318149dc68fc050132 912 SUPERFAMILY SSF55681 59 251 6.32E-57 T 23-10-2018 VMUT_0903 57276233eb14c4318149dc68fc050132 912 Gene3D G3DSA:3.30.54.20 663 718 4.8E-21 T 23-10-2018 VMUT_0903 57276233eb14c4318149dc68fc050132 912 Gene3D G3DSA:3.30.930.10 1 247 1.9E-103 T 23-10-2018 VMUT_0903 57276233eb14c4318149dc68fc050132 912 Hamap MF_00036_A Alanine--tRNA ligase [alaS]. 3 909 22.503 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 VMUT_0903 57276233eb14c4318149dc68fc050132 912 SUPERFAMILY SSF101353 292 497 1.44E-41 T 23-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 VMUT_0903 57276233eb14c4318149dc68fc050132 912 PRINTS PR00980 Alanyl-tRNA synthetase signature 206 217 5.5E-17 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 VMUT_0903 57276233eb14c4318149dc68fc050132 912 PRINTS PR00980 Alanyl-tRNA synthetase signature 127 138 5.5E-17 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 VMUT_0903 57276233eb14c4318149dc68fc050132 912 PRINTS PR00980 Alanyl-tRNA synthetase signature 346 359 5.5E-17 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 VMUT_0903 57276233eb14c4318149dc68fc050132 912 PRINTS PR00980 Alanyl-tRNA synthetase signature 322 338 5.5E-17 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 VMUT_0903 57276233eb14c4318149dc68fc050132 912 PRINTS PR00980 Alanyl-tRNA synthetase signature 232 245 5.5E-17 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 VMUT_0903 57276233eb14c4318149dc68fc050132 912 Gene3D G3DSA:2.40.30.130 491 587 8.2E-27 T 23-10-2018 VMUT_0903 57276233eb14c4318149dc68fc050132 912 SUPERFAMILY SSF55186 591 744 2.35E-41 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 VMUT_0903 57276233eb14c4318149dc68fc050132 912 Pfam PF01411 tRNA synthetases class II (A) 61 589 2.7E-116 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 VMUT_0903 57276233eb14c4318149dc68fc050132 912 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 690 735 3.8E-13 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 VMUT_0903 57276233eb14c4318149dc68fc050132 912 SUPERFAMILY SSF50447 500 573 2.12E-15 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VMUT_0903 57276233eb14c4318149dc68fc050132 912 SMART SM00863 690 737 5.8E-15 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 VMUT_0903 57276233eb14c4318149dc68fc050132 912 TIGRFAM TIGR03683 A-tRNA_syn_arch: alanine--tRNA ligase 2 910 0.0 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 VMUT_0903 57276233eb14c4318149dc68fc050132 912 Gene3D G3DSA:3.10.310.40 805 912 5.2E-7 T 23-10-2018 VMUT_1939 eb5a43da2ed126f3b8f905fbbade1a88 239 Gene3D G3DSA:3.30.470.20 87 224 3.2E-76 T 23-10-2018 VMUT_1939 eb5a43da2ed126f3b8f905fbbade1a88 239 ProSitePatterns PS01058 SAICAR synthetase signature 2. 176 184 - T 23-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 VMUT_1939 eb5a43da2ed126f3b8f905fbbade1a88 239 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 8 209 1.5E-57 T 23-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 VMUT_1939 eb5a43da2ed126f3b8f905fbbade1a88 239 SUPERFAMILY SSF56104 5 234 1.7E-69 T 23-10-2018 VMUT_1939 eb5a43da2ed126f3b8f905fbbade1a88 239 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 7 238 25.995 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 VMUT_1939 eb5a43da2ed126f3b8f905fbbade1a88 239 Gene3D G3DSA:3.30.200.20 10 232 3.2E-76 T 23-10-2018 VMUT_1939 eb5a43da2ed126f3b8f905fbbade1a88 239 Pfam PF01259 SAICAR synthetase 10 222 1.3E-52 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 VMUT_1939 eb5a43da2ed126f3b8f905fbbade1a88 239 ProSitePatterns PS01057 SAICAR synthetase signature 1. 88 102 - T 23-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 VMUT_1409 ecd03230410bed362881056f37782d7b 216 SUPERFAMILY SSF53335 9 180 1.37E-27 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_1409 ecd03230410bed362881056f37782d7b 216 Pfam PF08241 Methyltransferase domain 46 129 2.2E-13 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 VMUT_1409 ecd03230410bed362881056f37782d7b 216 Gene3D G3DSA:3.40.50.150 4 205 6.4E-41 T 23-10-2018 VMUT_2046 7f1d3e768a4d976545e2b02d3ed771ea 117 SUPERFAMILY SSF63562 28 106 1.36E-22 T 23-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 VMUT_2046 7f1d3e768a4d976545e2b02d3ed771ea 117 Gene3D G3DSA:3.90.940.10 11 106 7.7E-25 T 23-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 VMUT_2046 7f1d3e768a4d976545e2b02d3ed771ea 117 Pfam PF01192 RNA polymerase Rpb6 39 87 1.2E-14 T 23-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 VMUT_2046 7f1d3e768a4d976545e2b02d3ed771ea 117 SMART SM01409 37 87 2.8E-8 T 23-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 VMUT_2046 7f1d3e768a4d976545e2b02d3ed771ea 117 Hamap MF_00192 DNA-directed RNA polymerase subunit K [rpoK]. 36 93 19.38 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 VMUT_2046 7f1d3e768a4d976545e2b02d3ed771ea 117 PIRSF PIRSF000778 1 109 3.9E-28 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 VMUT_2046 7f1d3e768a4d976545e2b02d3ed771ea 117 ProSitePatterns PS01111 RNA polymerases K / 14 to 18 Kd subunits signature. 39 53 - T 23-10-2018 IPR020708 DNA-directed RNA polymerase, 14-18kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 VMUT_0862 b0e06829b1fb30d390f5ecd093508ccb 435 SUPERFAMILY SSF102114 155 225 3.27E-11 T 23-10-2018 VMUT_0862 b0e06829b1fb30d390f5ecd093508ccb 435 SUPERFAMILY SSF102114 268 403 9.29E-6 T 23-10-2018 VMUT_0862 b0e06829b1fb30d390f5ecd093508ccb 435 Pfam PF04055 Radical SAM superfamily 152 349 4.1E-11 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_0862 b0e06829b1fb30d390f5ecd093508ccb 435 Gene3D G3DSA:3.20.20.70 154 259 1.8E-9 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_1206 18d6d4bb9affb0287d995c4b127d9e5c 374 Gene3D G3DSA:3.50.50.60 3 341 3.1E-26 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_1206 18d6d4bb9affb0287d995c4b127d9e5c 374 Gene3D G3DSA:3.30.9.10 76 298 3.1E-26 T 23-10-2018 VMUT_1206 18d6d4bb9affb0287d995c4b127d9e5c 374 SUPERFAMILY SSF51905 1 362 1.94E-22 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_1206 18d6d4bb9affb0287d995c4b127d9e5c 374 Pfam PF01266 FAD dependent oxidoreductase 2 335 5.4E-17 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VMUT_0381 f526a76178c2673013c8287bc4adebbb 524 Hamap MF_00282 Phenylalanine--tRNA ligase alpha subunit [pheS]. 10 511 34.875 T 23-10-2018 IPR022917 Phenylalanine-tRNA ligase alpha subunit, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 VMUT_0381 f526a76178c2673013c8287bc4adebbb 524 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 204 507 1.6E-94 T 23-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 VMUT_0381 f526a76178c2673013c8287bc4adebbb 524 Pfam PF01409 tRNA synthetases class II core domain (F) 238 508 1.0E-81 T 23-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 VMUT_0381 f526a76178c2673013c8287bc4adebbb 524 Gene3D G3DSA:1.10.10.10 2 82 8.6E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_0381 f526a76178c2673013c8287bc4adebbb 524 Gene3D G3DSA:3.30.930.10 211 523 5.9E-97 T 23-10-2018 VMUT_0381 f526a76178c2673013c8287bc4adebbb 524 SUPERFAMILY SSF46785 11 86 2.19E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0381 f526a76178c2673013c8287bc4adebbb 524 SUPERFAMILY SSF55681 240 508 6.38E-62 T 23-10-2018 VMUT_1469 09416dff2b104c9a6cc882af36f04d76 285 Pfam PF01048 Phosphorylase superfamily 27 265 1.3E-37 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 VMUT_1469 09416dff2b104c9a6cc882af36f04d76 285 Gene3D G3DSA:3.40.50.1580 21 285 2.8E-84 T 23-10-2018 VMUT_1469 09416dff2b104c9a6cc882af36f04d76 285 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 73 113 - T 23-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 VMUT_1469 09416dff2b104c9a6cc882af36f04d76 285 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 25 285 41.044 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 VMUT_1469 09416dff2b104c9a6cc882af36f04d76 285 SUPERFAMILY SSF53167 25 283 4.87E-80 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 VMUT_1469 09416dff2b104c9a6cc882af36f04d76 285 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 27 266 4.5E-90 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 VMUT_0595 be193753720275ab002b24a0596dc16c 129 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 23-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 VMUT_0595 be193753720275ab002b24a0596dc16c 129 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 9 123 4.8E-34 T 23-10-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 VMUT_0595 be193753720275ab002b24a0596dc16c 129 SUPERFAMILY SSF53927 4 123 5.02E-38 T 23-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 VMUT_0595 be193753720275ab002b24a0596dc16c 129 Gene3D G3DSA:3.40.140.10 4 128 3.4E-39 T 23-10-2018 VMUT_0595 be193753720275ab002b24a0596dc16c 129 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 6 104 7.0E-15 T 23-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain VMUT_0832 ad1c47eee6754635a0d087f1f0ee60d5 334 SUPERFAMILY SSF53067 3 292 1.23E-27 T 23-10-2018 VMUT_0832 ad1c47eee6754635a0d087f1f0ee60d5 334 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 5 18 9.2E-40 T 23-10-2018 IPR017861 Kae1/TsaD family VMUT_0832 ad1c47eee6754635a0d087f1f0ee60d5 334 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 74 94 9.2E-40 T 23-10-2018 IPR017861 Kae1/TsaD family VMUT_0832 ad1c47eee6754635a0d087f1f0ee60d5 334 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 149 170 9.2E-40 T 23-10-2018 IPR017861 Kae1/TsaD family VMUT_0832 ad1c47eee6754635a0d087f1f0ee60d5 334 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 95 114 9.2E-40 T 23-10-2018 IPR017861 Kae1/TsaD family VMUT_0832 ad1c47eee6754635a0d087f1f0ee60d5 334 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 250 259 9.2E-40 T 23-10-2018 IPR017861 Kae1/TsaD family VMUT_0832 ad1c47eee6754635a0d087f1f0ee60d5 334 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 127 139 9.2E-40 T 23-10-2018 IPR017861 Kae1/TsaD family VMUT_0832 ad1c47eee6754635a0d087f1f0ee60d5 334 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 5 293 7.4E-79 T 23-10-2018 IPR017861 Kae1/TsaD family VMUT_0832 ad1c47eee6754635a0d087f1f0ee60d5 334 Pfam PF00814 Glycoprotease family 29 293 3.2E-73 T 23-10-2018 IPR000905 Gcp-like domain VMUT_0832 ad1c47eee6754635a0d087f1f0ee60d5 334 Gene3D G3DSA:3.30.420.40 4 302 1.8E-89 T 23-10-2018 VMUT_0832 ad1c47eee6754635a0d087f1f0ee60d5 334 Gene3D G3DSA:3.30.420.40 125 280 1.8E-89 T 23-10-2018 VMUT_0832 ad1c47eee6754635a0d087f1f0ee60d5 334 TIGRFAM TIGR03722 arch_KAE1: universal archaeal protein Kae1 4 326 1.1E-136 T 23-10-2018 IPR022449 tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea GO:0000408|GO:0002949 VMUT_0832 ad1c47eee6754635a0d087f1f0ee60d5 334 Hamap MF_01446 tRNA N6-adenosine threonylcarbamoyltransferase [kae1]. 2 327 36.398 T 23-10-2018 IPR034680 tRNA N6-adenosine threonylcarbamoyltransferase Kae1/OSGEP GO:0000408|GO:0002949 Reactome: R-HSA-6782315 VMUT_0019 a31f3967644b4c959c4d62101ae5fa27 121 Gene3D G3DSA:3.40.50.1010 1 121 4.7E-9 T 23-10-2018 VMUT_0019 a31f3967644b4c959c4d62101ae5fa27 121 SUPERFAMILY SSF88723 1 120 8.69E-14 T 23-10-2018 IPR029060 PIN-like domain superfamily VMUT_0019 a31f3967644b4c959c4d62101ae5fa27 121 Pfam PF01850 PIN domain 3 112 9.1E-12 T 23-10-2018 IPR002716 PIN domain VMUT_1881 752c78f28bae25920a5579c4a6f50bff 285 PIRSF PIRSF000193 12 274 1.4E-69 T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 VMUT_1881 752c78f28bae25920a5579c4a6f50bff 285 SUPERFAMILY SSF51735 14 167 5.07E-31 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1881 752c78f28bae25920a5579c4a6f50bff 285 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 13 108 2.4E-18 T 23-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal VMUT_1881 752c78f28bae25920a5579c4a6f50bff 285 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 12 271 22.968 T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 VMUT_1881 752c78f28bae25920a5579c4a6f50bff 285 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 169 270 2.4E-28 T 23-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 VMUT_1881 752c78f28bae25920a5579c4a6f50bff 285 Gene3D G3DSA:3.40.50.720 11 171 3.1E-47 T 23-10-2018 VMUT_1881 752c78f28bae25920a5579c4a6f50bff 285 Gene3D G3DSA:1.10.3730.10 172 273 1.6E-25 T 23-10-2018 VMUT_1881 752c78f28bae25920a5579c4a6f50bff 285 SUPERFAMILY SSF48179 168 274 8.16E-25 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VMUT_1881 752c78f28bae25920a5579c4a6f50bff 285 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 15 271 3.1E-67 T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 VMUT_1205 742175e13002096efc07d851978c0023 310 PIRSF PIRSF000676 1 294 2.3E-65 T 23-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 VMUT_1205 742175e13002096efc07d851978c0023 310 Gene3D G3DSA:3.30.230.10 1 156 4.2E-41 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup VMUT_1205 742175e13002096efc07d851978c0023 310 Pfam PF08544 GHMP kinases C terminal 226 276 2.4E-7 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain VMUT_1205 742175e13002096efc07d851978c0023 310 PRINTS PR00958 Homoserine kinase signature 134 147 3.2E-24 T 23-10-2018 VMUT_1205 742175e13002096efc07d851978c0023 310 PRINTS PR00958 Homoserine kinase signature 10 25 3.2E-24 T 23-10-2018 VMUT_1205 742175e13002096efc07d851978c0023 310 PRINTS PR00958 Homoserine kinase signature 251 266 3.2E-24 T 23-10-2018 VMUT_1205 742175e13002096efc07d851978c0023 310 PRINTS PR00958 Homoserine kinase signature 94 109 3.2E-24 T 23-10-2018 VMUT_1205 742175e13002096efc07d851978c0023 310 PRINTS PR00958 Homoserine kinase signature 171 188 3.2E-24 T 23-10-2018 VMUT_1205 742175e13002096efc07d851978c0023 310 Gene3D G3DSA:3.30.70.890 162 288 1.1E-24 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily VMUT_1205 742175e13002096efc07d851978c0023 310 Hamap MF_00384 Homoserine kinase [thrB]. 5 303 25.673 T 23-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 VMUT_1205 742175e13002096efc07d851978c0023 310 Pfam PF00288 GHMP kinases N terminal domain 80 147 1.7E-15 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 VMUT_1205 742175e13002096efc07d851978c0023 310 TIGRFAM TIGR00191 thrB: homoserine kinase 5 271 3.4E-51 T 23-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 VMUT_1205 742175e13002096efc07d851978c0023 310 SUPERFAMILY SSF55060 173 281 7.91E-23 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily VMUT_1205 742175e13002096efc07d851978c0023 310 SUPERFAMILY SSF54211 1 152 4.71E-33 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VMUT_2138 65d0be4467ee546ec83e7afaae9d8e2b 237 PIRSF PIRSF005902 1 237 8.0E-54 T 23-10-2018 IPR001130 TatD family GO:0016788 VMUT_2138 65d0be4467ee546ec83e7afaae9d8e2b 237 SUPERFAMILY SSF51556 2 237 6.53E-58 T 23-10-2018 IPR032466 Metal-dependent hydrolase VMUT_2138 65d0be4467ee546ec83e7afaae9d8e2b 237 Gene3D G3DSA:3.20.20.140 1 237 2.4E-58 T 23-10-2018 VMUT_2138 65d0be4467ee546ec83e7afaae9d8e2b 237 Pfam PF01026 TatD related DNase 4 236 3.0E-50 T 23-10-2018 IPR001130 TatD family GO:0016788 VMUT_0821 9519f789355ba887c2b6384f32269b1b 230 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 5 215 5.2E-52 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein VMUT_0821 9519f789355ba887c2b6384f32269b1b 230 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 3 229 43.176 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein VMUT_0821 9519f789355ba887c2b6384f32269b1b 230 Pfam PF03749 Sugar fermentation stimulation protein 15 217 3.4E-54 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein VMUT_0821 9519f789355ba887c2b6384f32269b1b 230 Gene3D G3DSA:3.40.1350.60 79 229 7.8E-43 T 23-10-2018 VMUT_0821 9519f789355ba887c2b6384f32269b1b 230 Gene3D G3DSA:2.40.50.580 3 78 4.2E-16 T 23-10-2018 VMUT_0560 0dcce640fa602ba9b242da8635078656 166 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 2 166 6.5E-41 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 VMUT_0560 0dcce640fa602ba9b242da8635078656 166 SUPERFAMILY SSF52540 2 166 4.69E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0560 0dcce640fa602ba9b242da8635078656 166 PIRSF PIRSF015617 1 166 4.3E-41 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 VMUT_0560 0dcce640fa602ba9b242da8635078656 166 Gene3D G3DSA:3.40.50.300 1 166 3.0E-42 T 23-10-2018 VMUT_1596 07c6957d4ba8b63a1a08745df064d4f2 248 Pfam PF00899 ThiF family 10 238 1.3E-61 T 23-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 VMUT_1596 07c6957d4ba8b63a1a08745df064d4f2 248 SUPERFAMILY SSF69572 7 243 7.59E-87 T 23-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 VMUT_1596 07c6957d4ba8b63a1a08745df064d4f2 248 Gene3D G3DSA:3.40.50.720 5 246 2.7E-79 T 23-10-2018 VMUT_0818 8abc25a4b1e99dda5fc1e3e7e5f59cfa 130 Gene3D G3DSA:3.40.50.1010 2 128 3.7E-15 T 23-10-2018 VMUT_0818 8abc25a4b1e99dda5fc1e3e7e5f59cfa 130 Pfam PF01850 PIN domain 2 120 7.5E-18 T 23-10-2018 IPR002716 PIN domain VMUT_0818 8abc25a4b1e99dda5fc1e3e7e5f59cfa 130 SMART SM00670 1 118 6.2E-10 T 23-10-2018 IPR002716 PIN domain VMUT_0818 8abc25a4b1e99dda5fc1e3e7e5f59cfa 130 SUPERFAMILY SSF88723 1 127 5.61E-20 T 23-10-2018 IPR029060 PIN-like domain superfamily VMUT_1250 2c689a443abd915454397f4fe8e65433 415 Pfam PF13407 Periplasmic binding protein domain 50 317 1.7E-34 T 23-10-2018 IPR025997 Periplasmic binding protein VMUT_1250 2c689a443abd915454397f4fe8e65433 415 Gene3D G3DSA:3.40.50.2300 38 163 5.2E-18 T 23-10-2018 VMUT_1250 2c689a443abd915454397f4fe8e65433 415 Gene3D G3DSA:3.40.50.2300 164 316 3.1E-20 T 23-10-2018 VMUT_1250 2c689a443abd915454397f4fe8e65433 415 SUPERFAMILY SSF53822 46 337 2.14E-37 T 23-10-2018 IPR028082 Periplasmic binding protein-like I VMUT_1273 2117bacb2d1964cbf4b757d78b639b6a 155 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 73 137 4.4E-11 T 23-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal VMUT_1273 2117bacb2d1964cbf4b757d78b639b6a 155 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 36 62 2.3E-5 T 23-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal VMUT_1273 2117bacb2d1964cbf4b757d78b639b6a 155 Gene3D G3DSA:1.10.12.20 1 75 1.6E-21 T 23-10-2018 VMUT_1273 2117bacb2d1964cbf4b757d78b639b6a 155 SUPERFAMILY SSF50249 11 142 3.6E-27 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold VMUT_1273 2117bacb2d1964cbf4b757d78b639b6a 155 Gene3D G3DSA:2.40.50.140 77 134 8.3E-14 T 23-10-2018 VMUT_0555 08b38881f53c1696e56650f7f22352e0 182 Gene3D G3DSA:3.40.30.10 23 180 4.9E-14 T 23-10-2018 VMUT_0555 08b38881f53c1696e56650f7f22352e0 182 Pfam PF13462 Thioredoxin 31 154 2.3E-9 T 23-10-2018 IPR012336 Thioredoxin-like fold VMUT_0555 08b38881f53c1696e56650f7f22352e0 182 SUPERFAMILY SSF52833 29 176 9.42E-16 T 23-10-2018 IPR036249 Thioredoxin-like superfamily VMUT_1498 8166314ad7c6a67fed0e93d030930d77 946 SUPERFAMILY SSF52540 9 202 2.57E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1498 8166314ad7c6a67fed0e93d030930d77 946 SMART SM00490 274 358 2.0E-17 T 23-10-2018 IPR001650 Helicase, C-terminal VMUT_1498 8166314ad7c6a67fed0e93d030930d77 946 Pfam PF00271 Helicase conserved C-terminal domain 254 354 5.0E-17 T 23-10-2018 IPR001650 Helicase, C-terminal VMUT_1498 8166314ad7c6a67fed0e93d030930d77 946 Gene3D G3DSA:3.40.50.300 8 208 9.1E-49 T 23-10-2018 VMUT_1498 8166314ad7c6a67fed0e93d030930d77 946 SMART SM00487 21 223 2.3E-33 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain VMUT_1498 8166314ad7c6a67fed0e93d030930d77 946 Gene3D G3DSA:3.40.50.300 229 418 2.9E-27 T 23-10-2018 VMUT_1498 8166314ad7c6a67fed0e93d030930d77 946 PIRSF PIRSF037307 2 945 1.5E-300 T 23-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 VMUT_1498 8166314ad7c6a67fed0e93d030930d77 946 Pfam PF00270 DEAD/DEAH box helicase 26 193 2.4E-30 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 VMUT_1498 8166314ad7c6a67fed0e93d030930d77 946 Pfam PF08494 DEAD/H associated 621 781 1.6E-22 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 VMUT_1498 8166314ad7c6a67fed0e93d030930d77 946 SUPERFAMILY SSF52540 146 367 5.62E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1498 8166314ad7c6a67fed0e93d030930d77 946 SMART SM00382 38 290 5.7E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0583 ac53e05799d97db5061f56a82cefc0cf 113 Pfam PF00428 60s Acidic ribosomal protein 17 112 5.1E-16 T 23-10-2018 VMUT_0583 ac53e05799d97db5061f56a82cefc0cf 113 Gene3D G3DSA:1.10.10.1410 1 58 2.7E-26 T 23-10-2018 IPR038716 Ribosomal protein P1/P2, N-terminal domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0583 ac53e05799d97db5061f56a82cefc0cf 113 Hamap MF_01478 50S ribosomal protein L12 [rpl12]. 1 110 13.384 T 23-10-2018 IPR027534 Ribosomal protein L12 family GO:0003735|GO:0005622|GO:0005840|GO:0006414 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0583 ac53e05799d97db5061f56a82cefc0cf 113 TIGRFAM TIGR03685 ribo_P1_arch: 50S ribosomal protein P1 1 113 1.5E-36 T 23-10-2018 IPR022295 Ribosomal protein L12, archaea GO:0003735|GO:0005840|GO:0006414 VMUT_0571 f55803205d3e42e0681387b80ca4420e 291 Pfam PF00902 Sec-independent protein translocase protein (TatC) 18 268 3.8E-44 T 23-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 VMUT_0571 f55803205d3e42e0681387b80ca4420e 291 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 149 175 1.1E-18 T 23-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 VMUT_0571 f55803205d3e42e0681387b80ca4420e 291 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 15 42 1.1E-18 T 23-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 VMUT_0571 f55803205d3e42e0681387b80ca4420e 291 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 201 229 1.1E-18 T 23-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 VMUT_0571 f55803205d3e42e0681387b80ca4420e 291 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 5 286 11.487 T 23-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 VMUT_1497 24a3008489023fa22b61e8e7aaf4eb13 157 SUPERFAMILY SSF88697 13 135 2.24E-6 T 23-10-2018 IPR015947 PUA-like superfamily VMUT_1497 24a3008489023fa22b61e8e7aaf4eb13 157 Gene3D G3DSA:3.10.590.10 1 135 3.9E-15 T 23-10-2018 VMUT_1741 aa3398c0733fd04f8a1dc4ef5216ed4d 327 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 42 60 2.9E-5 T 23-10-2018 IPR001270 ClpA/B family GO:0005524 VMUT_1741 aa3398c0733fd04f8a1dc4ef5216ed4d 327 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 108 126 2.9E-5 T 23-10-2018 IPR001270 ClpA/B family GO:0005524 VMUT_1741 aa3398c0733fd04f8a1dc4ef5216ed4d 327 Gene3D G3DSA:1.20.272.10 227 323 1.7E-13 T 23-10-2018 VMUT_1741 aa3398c0733fd04f8a1dc4ef5216ed4d 327 SMART SM00382 38 165 6.4E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_1741 aa3398c0733fd04f8a1dc4ef5216ed4d 327 SUPERFAMILY SSF52540 6 225 1.35E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1741 aa3398c0733fd04f8a1dc4ef5216ed4d 327 Pfam PF08542 Replication factor C C-terminal domain 228 317 3.9E-12 T 23-10-2018 IPR013748 Replication factor C, C-terminal Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-176187|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804756|Reactome: R-HSA-69091|Reactome: R-HSA-69473 VMUT_1741 aa3398c0733fd04f8a1dc4ef5216ed4d 327 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 42 157 1.1E-16 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VMUT_1741 aa3398c0733fd04f8a1dc4ef5216ed4d 327 SUPERFAMILY SSF48019 228 322 1.74E-13 T 23-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 VMUT_1741 aa3398c0733fd04f8a1dc4ef5216ed4d 327 Gene3D G3DSA:1.10.8.60 163 226 3.2E-25 T 23-10-2018 VMUT_1741 aa3398c0733fd04f8a1dc4ef5216ed4d 327 Gene3D G3DSA:3.40.50.300 1 162 1.6E-56 T 23-10-2018 VMUT_1124 7176d24459a50e2f7e50d09b764c9453 474 SUPERFAMILY SSF54292 321 396 9.04E-21 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VMUT_1124 7176d24459a50e2f7e50d09b764c9453 474 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 357 365 - T 23-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VMUT_1124 7176d24459a50e2f7e50d09b764c9453 474 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 13 181 6.4E-51 T 23-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 VMUT_1124 7176d24459a50e2f7e50d09b764c9453 474 SUPERFAMILY SSF56176 10 181 6.54E-53 T 23-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VMUT_1124 7176d24459a50e2f7e50d09b764c9453 474 Gene3D G3DSA:3.30.465.10 65 182 2.6E-38 T 23-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 VMUT_1124 7176d24459a50e2f7e50d09b764c9453 474 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 188 286 1.0E-4 T 23-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal VMUT_1124 7176d24459a50e2f7e50d09b764c9453 474 SUPERFAMILY SSF55447 187 291 1.18E-11 T 23-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily VMUT_1124 7176d24459a50e2f7e50d09b764c9453 474 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 325 374 3.2E-6 T 23-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VMUT_1124 7176d24459a50e2f7e50d09b764c9453 474 Pfam PF01799 [2Fe-2S] binding domain 391 464 7.6E-22 T 23-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 VMUT_1124 7176d24459a50e2f7e50d09b764c9453 474 Gene3D G3DSA:3.30.43.10 9 61 4.5E-20 T 23-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 VMUT_1124 7176d24459a50e2f7e50d09b764c9453 474 SMART SM01092 186 288 2.6E-4 T 23-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal VMUT_1124 7176d24459a50e2f7e50d09b764c9453 474 Gene3D G3DSA:3.30.390.50 184 290 4.4E-10 T 23-10-2018 VMUT_1124 7176d24459a50e2f7e50d09b764c9453 474 Gene3D G3DSA:3.10.20.30 314 392 3.4E-25 T 23-10-2018 IPR012675 Beta-grasp domain superfamily VMUT_1124 7176d24459a50e2f7e50d09b764c9453 474 Gene3D G3DSA:1.10.150.120 393 473 1.4E-23 T 23-10-2018 VMUT_1124 7176d24459a50e2f7e50d09b764c9453 474 SUPERFAMILY SSF47741 402 471 2.62E-24 T 23-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily VMUT_0230 26380d1377acb35e942f09c108084852 271 Gene3D G3DSA:3.40.1080.10 7 270 2.1E-71 T 23-10-2018 VMUT_0230 26380d1377acb35e942f09c108084852 271 Pfam PF01144 Coenzyme A transferase 7 227 1.5E-27 T 23-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 VMUT_0230 26380d1377acb35e942f09c108084852 271 SMART SM00882 6 228 1.3E-33 T 23-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 VMUT_0230 26380d1377acb35e942f09c108084852 271 SUPERFAMILY SSF100950 4 255 6.98E-68 T 23-10-2018 IPR037171 NagB/RpiA transferase-like VMUT_0230 26380d1377acb35e942f09c108084852 271 Gene3D G3DSA:3.30.30.40 117 156 2.1E-71 T 23-10-2018 VMUT_1054 11d7eee79038b82fdd7a71bece56a8f6 217 SUPERFAMILY SSF53448 8 215 1.78E-21 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1054 11d7eee79038b82fdd7a71bece56a8f6 217 Pfam PF00535 Glycosyl transferase family 2 8 106 8.2E-11 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VMUT_1054 11d7eee79038b82fdd7a71bece56a8f6 217 Gene3D G3DSA:3.90.550.10 2 217 1.3E-16 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0927 5d93fa17b89e57fea31f48a1e11813a0 593 Pfam PF09843 Predicted membrane protein (DUF2070) 7 582 3.2E-113 T 23-10-2018 IPR019204 Domain of unknown function DUF2070, membrane VMUT_0037 4285034b95b95f0ef4a2f0df3b0a63be 585 SMART SM00382 289 474 3.1E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0037 4285034b95b95f0ef4a2f0df3b0a63be 585 Gene3D G3DSA:3.40.50.300 277 482 2.6E-18 T 23-10-2018 VMUT_0037 4285034b95b95f0ef4a2f0df3b0a63be 585 SUPERFAMILY SSF52540 263 546 7.12E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0037 4285034b95b95f0ef4a2f0df3b0a63be 585 Pfam PF07728 AAA domain (dynein-related subfamily) 292 466 9.8E-13 T 23-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 VMUT_0665 227eaa113b515a93439354ca4e7b5e8a 174 Hamap MF_00590 UPF0218 protein . 5 172 22.017 T 23-10-2018 IPR007164 Protein of unknown function DUF359 VMUT_0665 227eaa113b515a93439354ca4e7b5e8a 174 Pfam PF04019 Protein of unknown function (DUF359) 48 169 3.6E-29 T 23-10-2018 IPR007164 Protein of unknown function DUF359 VMUT_1427 132e33696ccd4748e6468e56e7e78439 274 SUPERFAMILY SSF54211 24 147 5.46E-18 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VMUT_1427 132e33696ccd4748e6468e56e7e78439 274 TIGRFAM TIGR01920 Shik_kin_archae: shikimate kinase 10 247 2.2E-61 T 23-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 VMUT_1427 132e33696ccd4748e6468e56e7e78439 274 Hamap MF_00370 Shikimate kinase [aroK]. 1 274 68.014 T 23-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 VMUT_1427 132e33696ccd4748e6468e56e7e78439 274 Gene3D G3DSA:3.30.230.10 27 151 3.6E-17 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup VMUT_1427 132e33696ccd4748e6468e56e7e78439 274 SUPERFAMILY SSF55060 209 262 4.8E-5 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily VMUT_1427 132e33696ccd4748e6468e56e7e78439 274 Pfam PF00288 GHMP kinases N terminal domain 68 136 2.2E-11 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 VMUT_1427 132e33696ccd4748e6468e56e7e78439 274 PIRSF PIRSF005758 4 272 4.7E-65 T 23-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 VMUT_1507 135fd7a0e4230409029dc9e851706e2b 100 Gene3D G3DSA:3.30.1360.20 1 96 1.6E-28 T 23-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 VMUT_1507 135fd7a0e4230409029dc9e851706e2b 100 SUPERFAMILY SSF55248 6 89 2.88E-26 T 23-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 VMUT_1507 135fd7a0e4230409029dc9e851706e2b 100 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 1 89 19.799 T 23-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 VMUT_1507 135fd7a0e4230409029dc9e851706e2b 100 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 2 88 3.8E-27 T 23-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 VMUT_2253 fb6ae97a039afd488b44d4b532a8e8b6 492 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 6 272 3.7E-79 T 23-10-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal VMUT_2253 fb6ae97a039afd488b44d4b532a8e8b6 492 Gene3D G3DSA:1.20.140.10 276 479 1.4E-49 T 23-10-2018 VMUT_2253 fb6ae97a039afd488b44d4b532a8e8b6 492 SUPERFAMILY SSF56645 1 272 8.74E-62 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VMUT_2253 fb6ae97a039afd488b44d4b532a8e8b6 492 Gene3D G3DSA:1.10.3140.10 1 143 1.4E-32 T 23-10-2018 VMUT_2253 fb6ae97a039afd488b44d4b532a8e8b6 492 SUPERFAMILY SSF47203 263 468 2.51E-45 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VMUT_2253 fb6ae97a039afd488b44d4b532a8e8b6 492 PIRSF PIRSF000331 1 489 2.3E-118 T 23-10-2018 IPR004925 HpaB/PvcC/4-BUDH VMUT_2253 fb6ae97a039afd488b44d4b532a8e8b6 492 Gene3D G3DSA:2.40.110.10 144 273 1.8E-37 T 23-10-2018 VMUT_2253 fb6ae97a039afd488b44d4b532a8e8b6 492 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 285 467 1.0E-40 T 23-10-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal VMUT_1826 63083c700251003bae8337ff4fa16d46 275 Gene3D G3DSA:3.40.30.10 1 78 1.1E-10 T 23-10-2018 VMUT_1826 63083c700251003bae8337ff4fa16d46 275 SUPERFAMILY SSF52833 2 78 3.12E-13 T 23-10-2018 IPR036249 Thioredoxin-like superfamily VMUT_1826 63083c700251003bae8337ff4fa16d46 275 Pfam PF13192 Thioredoxin domain 5 77 2.2E-9 T 23-10-2018 IPR012336 Thioredoxin-like fold VMUT_0735 f07a75a2a7f7bcd09c5e1ed1aec04ea8 1037 SUPERFAMILY SSF52540 209 390 5.6E-24 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0735 f07a75a2a7f7bcd09c5e1ed1aec04ea8 1037 SMART SM00306 388 480 9.7E-14 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 VMUT_0735 f07a75a2a7f7bcd09c5e1ed1aec04ea8 1037 Gene3D G3DSA:2.170.16.10 391 494 1.1E-12 T 23-10-2018 VMUT_0735 f07a75a2a7f7bcd09c5e1ed1aec04ea8 1037 SMART SM00487 278 451 5.3E-5 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain VMUT_0735 f07a75a2a7f7bcd09c5e1ed1aec04ea8 1037 Pfam PF00271 Helicase conserved C-terminal domain 865 973 5.4E-19 T 23-10-2018 IPR001650 Helicase, C-terminal VMUT_0735 f07a75a2a7f7bcd09c5e1ed1aec04ea8 1037 SMART SM00490 894 974 4.6E-19 T 23-10-2018 IPR001650 Helicase, C-terminal VMUT_0735 f07a75a2a7f7bcd09c5e1ed1aec04ea8 1037 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 744 766 3.6E-10 T 23-10-2018 IPR030934 Intein C-terminal splicing region VMUT_0735 f07a75a2a7f7bcd09c5e1ed1aec04ea8 1037 SMART SM00305 735 771 9.1E-6 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 VMUT_0735 f07a75a2a7f7bcd09c5e1ed1aec04ea8 1037 Gene3D G3DSA:3.40.50.300 271 390 1.2E-24 T 23-10-2018 VMUT_0735 f07a75a2a7f7bcd09c5e1ed1aec04ea8 1037 Gene3D G3DSA:2.170.16.10 715 767 1.2E-6 T 23-10-2018 VMUT_0735 f07a75a2a7f7bcd09c5e1ed1aec04ea8 1037 Gene3D G3DSA:3.40.50.300 818 1020 1.7E-42 T 23-10-2018 VMUT_0735 f07a75a2a7f7bcd09c5e1ed1aec04ea8 1037 SUPERFAMILY SSF52540 828 1006 2.42E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0735 f07a75a2a7f7bcd09c5e1ed1aec04ea8 1037 Pfam PF04851 Type III restriction enzyme, res subunit 280 390 3.3E-7 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 VMUT_0735 f07a75a2a7f7bcd09c5e1ed1aec04ea8 1037 SUPERFAMILY SSF51294 390 765 2.16E-21 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 VMUT_0028 77d2198f358723a7678975f7e98454af 510 SUPERFAMILY SSF56801 9 510 7.85E-113 T 23-10-2018 VMUT_0028 77d2198f358723a7678975f7e98454af 510 Gene3D G3DSA:3.30.300.310 418 510 7.4E-21 T 23-10-2018 VMUT_0028 77d2198f358723a7678975f7e98454af 510 ProSitePatterns PS00455 Putative AMP-binding domain signature. 163 174 - T 23-10-2018 IPR020845 AMP-binding, conserved site VMUT_0028 77d2198f358723a7678975f7e98454af 510 Pfam PF00501 AMP-binding enzyme 23 422 3.7E-78 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VMUT_0028 77d2198f358723a7678975f7e98454af 510 Pfam PF13193 AMP-binding enzyme C-terminal domain 432 510 1.4E-15 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VMUT_0028 77d2198f358723a7678975f7e98454af 510 Gene3D G3DSA:3.40.50.12780 6 417 2.3E-81 T 23-10-2018 VMUT_0645 c450286acdd4cf95ff2cdffd7792407d 61 Pfam PF09082 Domain of unknown function (DUF1922) 5 54 3.4E-6 T 23-10-2018 IPR015166 Protein of unknown function DUF1922 VMUT_0645 c450286acdd4cf95ff2cdffd7792407d 61 SUPERFAMILY SSF57821 5 54 3.01E-5 T 23-10-2018 IPR036304 Hypothetical protein MTH1184 VMUT_0645 c450286acdd4cf95ff2cdffd7792407d 61 Gene3D G3DSA:3.90.820.10 1 58 4.3E-10 T 23-10-2018 VMUT_1420 97900e94db2bc6a8875cf5f34807af87 334 SUPERFAMILY SSF47648 1 66 1.26E-12 T 23-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 VMUT_1420 97900e94db2bc6a8875cf5f34807af87 334 Gene3D G3DSA:1.20.970.10 5 182 1.5E-110 T 23-10-2018 VMUT_1420 97900e94db2bc6a8875cf5f34807af87 334 Gene3D G3DSA:3.40.1030.10 70 313 1.5E-110 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 VMUT_1420 97900e94db2bc6a8875cf5f34807af87 334 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 5 320 9.2E-109 T 23-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 VMUT_1420 97900e94db2bc6a8875cf5f34807af87 334 Pfam PF00591 Glycosyl transferase family, a/b domain 73 320 2.3E-79 T 23-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 VMUT_1420 97900e94db2bc6a8875cf5f34807af87 334 Pfam PF02885 Glycosyl transferase family, helical bundle domain 3 61 2.1E-10 T 23-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 VMUT_1420 97900e94db2bc6a8875cf5f34807af87 334 SUPERFAMILY SSF52418 72 320 4.45E-80 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 VMUT_1420 97900e94db2bc6a8875cf5f34807af87 334 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 3 331 34.669 T 23-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 VMUT_2002 bfc220acd49590c8aa9996b084278c3c 466 SUPERFAMILY SSF48452 180 382 2.31E-6 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VMUT_2002 bfc220acd49590c8aa9996b084278c3c 466 Gene3D G3DSA:1.25.40.10 126 422 1.6E-11 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VMUT_0823 471568c48c3bb47feea91c0d0e5b3aff 380 SUPERFAMILY SSF103473 11 373 3.14E-39 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_0823 471568c48c3bb47feea91c0d0e5b3aff 380 Gene3D G3DSA:1.20.1250.20 4 184 1.9E-14 T 23-10-2018 VMUT_0823 471568c48c3bb47feea91c0d0e5b3aff 380 Pfam PF07690 Major Facilitator Superfamily 200 372 5.2E-17 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_0823 471568c48c3bb47feea91c0d0e5b3aff 380 Gene3D G3DSA:1.20.1250.20 186 377 1.3E-21 T 23-10-2018 VMUT_1422 3c03efdbf78a65cce3f6f6f555489999 239 Gene3D G3DSA:3.20.20.70 3 236 5.7E-41 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_1422 3c03efdbf78a65cce3f6f6f555489999 239 Pfam PF00290 Tryptophan synthase alpha chain 10 225 9.4E-25 T 23-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 VMUT_1422 3c03efdbf78a65cce3f6f6f555489999 239 SUPERFAMILY SSF51366 5 224 1.88E-42 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 VMUT_1533 0e82476df07dbd454c84614ccb9cfd0d 358 SUPERFAMILY SSF55347 157 325 6.8E-45 T 23-10-2018 VMUT_1533 0e82476df07dbd454c84614ccb9cfd0d 358 SUPERFAMILY SSF51735 5 186 3.55E-52 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1533 0e82476df07dbd454c84614ccb9cfd0d 358 Hamap MF_02083 [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase [lysY]. 6 357 54.305 T 23-10-2018 IPR037535 [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase GO:0016620 VMUT_1533 0e82476df07dbd454c84614ccb9cfd0d 358 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 7 148 6.7E-34 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 VMUT_1533 0e82476df07dbd454c84614ccb9cfd0d 358 SMART SM00859 7 149 3.1E-53 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 VMUT_1533 0e82476df07dbd454c84614ccb9cfd0d 358 Gene3D G3DSA:3.30.360.10 155 325 2.1E-116 T 23-10-2018 VMUT_1533 0e82476df07dbd454c84614ccb9cfd0d 358 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 6 351 42.323 T 23-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 VMUT_1533 0e82476df07dbd454c84614ccb9cfd0d 358 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 7 357 3.4E-129 T 23-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 VMUT_1533 0e82476df07dbd454c84614ccb9cfd0d 358 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 166 328 1.5E-14 T 23-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 VMUT_1533 0e82476df07dbd454c84614ccb9cfd0d 358 Gene3D G3DSA:3.40.50.720 7 343 2.1E-116 T 23-10-2018 VMUT_0482 b0e910ee467d205b9f6ee4b6c6a6d667 473 Pfam PF01925 Sulfite exporter TauE/SafE 15 280 4.4E-41 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 VMUT_0482 b0e910ee467d205b9f6ee4b6c6a6d667 473 Pfam PF07843 Protein of unknown function (DUF1634) 350 464 6.3E-23 T 23-10-2018 IPR012861 Protein of unknown function DUF1634 VMUT_0123 c0ca6e4739f82b1213ed7bc08ec346ce 156 Gene3D G3DSA:3.40.50.620 7 153 2.0E-37 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_0123 c0ca6e4739f82b1213ed7bc08ec346ce 156 SUPERFAMILY SSF52374 7 148 8.45E-20 T 23-10-2018 VMUT_0123 c0ca6e4739f82b1213ed7bc08ec346ce 156 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 9 70 1.8E-12 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 VMUT_0123 c0ca6e4739f82b1213ed7bc08ec346ce 156 Pfam PF01467 Cytidylyltransferase-like 11 148 2.5E-14 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 VMUT_0446 f0d79a1d3ead15147cd4d309f2ab455c 412 Pfam PF01546 Peptidase family M20/M25/M40 93 404 3.8E-31 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 VMUT_0446 f0d79a1d3ead15147cd4d309f2ab455c 412 Pfam PF07687 Peptidase dimerisation domain 202 309 1.5E-18 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain VMUT_0446 f0d79a1d3ead15147cd4d309f2ab455c 412 SUPERFAMILY SSF55031 206 321 9.42E-22 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VMUT_0446 f0d79a1d3ead15147cd4d309f2ab455c 412 Gene3D G3DSA:3.40.630.10 57 397 2.0E-71 T 23-10-2018 VMUT_0446 f0d79a1d3ead15147cd4d309f2ab455c 412 Gene3D G3DSA:3.30.70.360 206 328 2.0E-71 T 23-10-2018 VMUT_0446 f0d79a1d3ead15147cd4d309f2ab455c 412 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 21 402 3.3E-73 T 23-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase VMUT_0446 f0d79a1d3ead15147cd4d309f2ab455c 412 SUPERFAMILY SSF53187 6 405 5.14E-52 T 23-10-2018 VMUT_1692 6ed61049b665b05154d2b52fd817a3af 232 SUPERFAMILY SSF89895 2 84 7.06E-23 T 23-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily VMUT_1692 6ed61049b665b05154d2b52fd817a3af 232 SUPERFAMILY SSF109728 80 153 6.93E-23 T 23-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily VMUT_1692 6ed61049b665b05154d2b52fd817a3af 232 Pfam PF09377 SBDS protein C-terminal domain 99 213 2.5E-16 T 23-10-2018 IPR018978 Ribosome maturation protein SBDS, C-terminal GO:0042254 VMUT_1692 6ed61049b665b05154d2b52fd817a3af 232 Gene3D G3DSA:3.30.1250.10 6 85 4.5E-27 T 23-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily VMUT_1692 6ed61049b665b05154d2b52fd817a3af 232 Gene3D G3DSA:3.30.70.240 163 230 4.4E-19 T 23-10-2018 VMUT_1692 6ed61049b665b05154d2b52fd817a3af 232 TIGRFAM TIGR00291 RNA_SBDS: rRNA metabolism protein, SBDS family 4 226 1.5E-66 T 23-10-2018 IPR002140 Ribosome maturation protein Sdo1/SBDS GO:0042256 VMUT_1692 6ed61049b665b05154d2b52fd817a3af 232 Pfam PF01172 Shwachman-Bodian-Diamond syndrome (SBDS) protein 5 92 5.4E-22 T 23-10-2018 IPR019783 Ribosome maturation protein SBDS, N-terminal VMUT_1692 6ed61049b665b05154d2b52fd817a3af 232 SUPERFAMILY SSF54980 155 227 2.3E-17 T 23-10-2018 IPR035647 EF-G domain III/V-like VMUT_1692 6ed61049b665b05154d2b52fd817a3af 232 Gene3D G3DSA:1.10.10.900 86 160 4.8E-29 T 23-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily VMUT_2057 3fbf0f1e0f929787903437b216bae4dd 90 ProDom PD005155 RNA POLYMERASE DNA-DIRECTED SUBUNIT NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION II H POLYPEPTIDE 21 88 2.0E-16 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 VMUT_2057 3fbf0f1e0f929787903437b216bae4dd 90 Hamap MF_00025 DNA-directed RNA polymerase subunit H [rpoH]. 15 88 22.134 T 23-10-2018 IPR020609 Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 VMUT_2057 3fbf0f1e0f929787903437b216bae4dd 90 Gene3D G3DSA:3.90.940.20 7 90 1.7E-28 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 VMUT_2057 3fbf0f1e0f929787903437b216bae4dd 90 Pfam PF01191 RNA polymerase Rpb5, C-terminal domain 17 87 5.6E-29 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 VMUT_2057 3fbf0f1e0f929787903437b216bae4dd 90 SUPERFAMILY SSF55287 16 88 2.49E-25 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 VMUT_1792 8b8eecdf6ee88fc09ee281958d7483a2 529 Gene3D G3DSA:3.40.50.300 323 509 4.0E-33 T 23-10-2018 VMUT_1792 8b8eecdf6ee88fc09ee281958d7483a2 529 Gene3D G3DSA:3.40.50.300 124 322 1.1E-20 T 23-10-2018 VMUT_1792 8b8eecdf6ee88fc09ee281958d7483a2 529 SUPERFAMILY SSF52540 115 512 2.0E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1792 8b8eecdf6ee88fc09ee281958d7483a2 529 Pfam PF01935 Domain of unknown function DUF87 141 388 1.4E-36 T 23-10-2018 IPR002789 Helicase HerA, central domain VMUT_0782 aa77933a44d938e40b67fbfb44c0133e 131 SUPERFAMILY SSF46785 8 108 1.8E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0782 aa77933a44d938e40b67fbfb44c0133e 131 Gene3D G3DSA:1.10.10.10 4 109 1.3E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_1334 a7db63ca318490f37eff07c0246169ef 346 Gene3D G3DSA:3.40.640.10 32 250 2.3E-77 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VMUT_1334 a7db63ca318490f37eff07c0246169ef 346 Pfam PF00155 Aminotransferase class I and II 20 296 2.1E-31 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VMUT_1334 a7db63ca318490f37eff07c0246169ef 346 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 206 219 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 VMUT_1334 a7db63ca318490f37eff07c0246169ef 346 SUPERFAMILY SSF53383 18 341 3.03E-58 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VMUT_1334 a7db63ca318490f37eff07c0246169ef 346 Gene3D G3DSA:3.90.1150.10 20 338 2.3E-77 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VMUT_1512 ab73d3b321235c2b3896d5beba783b45 429 Pfam PF07690 Major Facilitator Superfamily 27 380 1.6E-22 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_1512 ab73d3b321235c2b3896d5beba783b45 429 SUPERFAMILY SSF103473 12 422 2.88E-48 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_1512 ab73d3b321235c2b3896d5beba783b45 429 Gene3D G3DSA:1.20.1250.20 11 428 2.2E-49 T 23-10-2018 VMUT_1869 1473e46ce062d31e7879776a58fee233 377 Pfam PF02562 PhoH-like protein 7 209 5.3E-50 T 23-10-2018 IPR003714 PhoH-like protein GO:0005524 VMUT_1869 1473e46ce062d31e7879776a58fee233 377 SUPERFAMILY SSF52540 8 219 2.41E-13 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1869 1473e46ce062d31e7879776a58fee233 377 Pfam PF07650 KH domain 246 301 5.9E-7 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1869 1473e46ce062d31e7879776a58fee233 377 Gene3D G3DSA:3.40.50.300 5 211 2.1E-36 T 23-10-2018 VMUT_0466 21a3a079c1c3103eaefe6e43f8cfa722 347 Pfam PF01896 DNA primase small subunit 93 276 8.5E-26 T 23-10-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 VMUT_0466 21a3a079c1c3103eaefe6e43f8cfa722 347 SUPERFAMILY SSF56747 7 345 8.28E-74 T 23-10-2018 VMUT_0466 21a3a079c1c3103eaefe6e43f8cfa722 347 TIGRFAM TIGR00335 primase_sml: putative DNA primase, eukaryotic-type, small subunit 22 177 1.4E-44 T 23-10-2018 IPR014052 DNA primase, small subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 VMUT_0466 21a3a079c1c3103eaefe6e43f8cfa722 347 Hamap MF_00700 DNA primase small subunit PriS [priS]. 6 341 28.335 T 23-10-2018 IPR023639 DNA primase small subunit PriS GO:0003896 VMUT_1151 f0674c2c72fff500cf5303e16520f6a3 389 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 7 386 2.7E-119 T 23-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 VMUT_1598 b3b10230105470fe85bef4b14fcc2f3a 219 Hamap MF_01218_A Uracil phosphoribosyltransferase [upp]. 2 217 43.005 T 23-10-2018 IPR034331 Uracil phosphoribosyltransferase, archaea GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 VMUT_1598 b3b10230105470fe85bef4b14fcc2f3a 219 Pfam PF14681 Uracil phosphoribosyltransferase 6 217 4.8E-49 T 23-10-2018 VMUT_1598 b3b10230105470fe85bef4b14fcc2f3a 219 Gene3D G3DSA:3.40.50.2020 3 217 6.3E-62 T 23-10-2018 VMUT_1598 b3b10230105470fe85bef4b14fcc2f3a 219 SUPERFAMILY SSF53271 4 217 1.2E-59 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like VMUT_1598 b3b10230105470fe85bef4b14fcc2f3a 219 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 217 1.7E-70 T 23-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 VMUT_0791 6a10291d0ea8f7db989422bd460451fa 620 Pfam PF17392 Urocanase C-terminal domain 368 563 2.4E-82 T 23-10-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 VMUT_0791 6a10291d0ea8f7db989422bd460451fa 620 SUPERFAMILY SSF111326 38 572 5.49E-218 T 23-10-2018 IPR036190 Urocanase superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 VMUT_0791 6a10291d0ea8f7db989422bd460451fa 620 Pfam PF01175 Urocanase Rossmann-like domain 159 364 7.4E-81 T 23-10-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 VMUT_0791 6a10291d0ea8f7db989422bd460451fa 620 Gene3D G3DSA:3.40.50.10730 160 365 1.7E-212 T 23-10-2018 IPR038364 Urocanase, central domain superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 VMUT_0791 6a10291d0ea8f7db989422bd460451fa 620 Pfam PF17391 Urocanase N-terminal domain 38 155 1.2E-42 T 23-10-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 VMUT_0791 6a10291d0ea8f7db989422bd460451fa 620 Gene3D G3DSA:3.40.1770.10 39 558 1.7E-212 T 23-10-2018 VMUT_0791 6a10291d0ea8f7db989422bd460451fa 620 TIGRFAM TIGR01228 hutU: urocanate hydratase 28 570 1.7E-232 T 23-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 VMUT_0791 6a10291d0ea8f7db989422bd460451fa 620 Hamap MF_00577 Urocanate hydratase [hutU]. 7 573 44.479 T 23-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 VMUT_0791 6a10291d0ea8f7db989422bd460451fa 620 PIRSF PIRSF001423 17 578 8.9E-237 T 23-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 VMUT_0791 6a10291d0ea8f7db989422bd460451fa 620 ProSitePatterns PS01233 Urocanase signature. 459 474 - T 23-10-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 VMUT_0201 fb64a1d54235321ec45501f9d2253457 232 Gene3D G3DSA:3.40.50.620 1 126 8.5E-34 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_0201 fb64a1d54235321ec45501f9d2253457 232 PIRSF PIRSF039123 1 231 1.4E-69 T 23-10-2018 IPR030662 Diphthine--ammonia ligase/Uncharacterised protein MJ0570 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 VMUT_0201 fb64a1d54235321ec45501f9d2253457 232 Pfam PF01902 Diphthamide synthase 1 221 4.9E-53 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 VMUT_0201 fb64a1d54235321ec45501f9d2253457 232 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 1 221 3.3E-53 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 VMUT_0201 fb64a1d54235321ec45501f9d2253457 232 TIGRFAM TIGR03679 arCOG00187: arCOG00187 universal archaeal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein 4 222 1.4E-75 T 23-10-2018 IPR022427 Uncharacterised protein MJ0570, ATP-binding VMUT_0201 fb64a1d54235321ec45501f9d2253457 232 SUPERFAMILY SSF52402 1 219 8.13E-64 T 23-10-2018 VMUT_0201 fb64a1d54235321ec45501f9d2253457 232 Gene3D G3DSA:3.90.1490.10 127 228 4.6E-24 T 23-10-2018 VMUT_2067 a8f0cf2c323a6bd1cd652ee347691cff 417 Gene3D G3DSA:1.20.1250.20 220 412 5.7E-19 T 23-10-2018 VMUT_2067 a8f0cf2c323a6bd1cd652ee347691cff 417 ProSitePatterns PS00216 Sugar transport proteins signature 1. 280 297 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VMUT_2067 a8f0cf2c323a6bd1cd652ee347691cff 417 Pfam PF07690 Major Facilitator Superfamily 18 263 4.0E-18 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_2067 a8f0cf2c323a6bd1cd652ee347691cff 417 Gene3D G3DSA:1.20.1250.20 7 195 2.9E-12 T 23-10-2018 VMUT_2067 a8f0cf2c323a6bd1cd652ee347691cff 417 SUPERFAMILY SSF103473 8 410 5.1E-41 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_0675 df9c47f3636f118c2a810ee3c517bf9d 480 PIRSF PIRSF006060 1 475 1.6E-41 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_0675 df9c47f3636f118c2a810ee3c517bf9d 480 Pfam PF00324 Amino acid permease 27 467 1.8E-26 T 23-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 VMUT_0675 df9c47f3636f118c2a810ee3c517bf9d 480 Gene3D G3DSA:1.20.1740.10 18 477 2.7E-25 T 23-10-2018 VMUT_0414 4f2a964079ca7a10061a6828fa97cf0f 568 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 22 563 1.9E-105 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 VMUT_0414 4f2a964079ca7a10061a6828fa97cf0f 568 Gene3D G3DSA:3.40.50.620 23 296 2.2E-75 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_0414 4f2a964079ca7a10061a6828fa97cf0f 568 Gene3D G3DSA:1.10.10.350 473 565 1.7E-18 T 23-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 VMUT_0414 4f2a964079ca7a10061a6828fa97cf0f 568 SUPERFAMILY SSF48163 350 565 1.7E-27 T 23-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 VMUT_0414 4f2a964079ca7a10061a6828fa97cf0f 568 Gene3D G3DSA:1.10.10.770 348 471 3.5E-26 T 23-10-2018 VMUT_0414 4f2a964079ca7a10061a6828fa97cf0f 568 Pfam PF01921 tRNA synthetases class I (K) 21 373 1.4E-99 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 VMUT_0414 4f2a964079ca7a10061a6828fa97cf0f 568 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 21 567 30.307 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 VMUT_0414 4f2a964079ca7a10061a6828fa97cf0f 568 SUPERFAMILY SSF52374 22 348 1.41E-33 T 23-10-2018 VMUT_0414 4f2a964079ca7a10061a6828fa97cf0f 568 Gene3D G3DSA:2.30.30.300 195 241 2.2E-75 T 23-10-2018 IPR023386 Lysine-tRNA ligase, insertion domain superfamily GO:0004824 KEGG: 00970+6.1.1.6 VMUT_1359 552a5014d21848a308c666b358a70e7d 113 Pfam PF00355 Rieske [2Fe-2S] domain 13 92 9.3E-12 T 23-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 VMUT_1359 552a5014d21848a308c666b358a70e7d 113 SUPERFAMILY SSF50022 15 111 1.2E-19 T 23-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VMUT_1359 552a5014d21848a308c666b358a70e7d 113 Gene3D G3DSA:2.102.10.10 2 112 1.4E-16 T 23-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VMUT_0881 e7f1fd27eb5de16c3246c603a2e483f3 275 Gene3D G3DSA:1.10.1040.10 145 268 9.1E-20 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VMUT_0881 e7f1fd27eb5de16c3246c603a2e483f3 275 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 150 261 2.2E-14 T 23-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 VMUT_0881 e7f1fd27eb5de16c3246c603a2e483f3 275 SUPERFAMILY SSF48179 149 261 4.0E-19 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VMUT_0881 e7f1fd27eb5de16c3246c603a2e483f3 275 Gene3D G3DSA:3.40.50.720 1 141 1.3E-24 T 23-10-2018 VMUT_0881 e7f1fd27eb5de16c3246c603a2e483f3 275 PIRSF PIRSF000103 1 271 1.2E-53 T 23-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 VMUT_0881 e7f1fd27eb5de16c3246c603a2e483f3 275 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 141 7.6E-20 T 23-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 VMUT_0881 e7f1fd27eb5de16c3246c603a2e483f3 275 SUPERFAMILY SSF51735 1 142 1.51E-23 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0289 c3fd8908b9163fda2dbffe73471048bb 260 Gene3D G3DSA:1.10.150.20 142 213 1.9E-10 T 23-10-2018 VMUT_0289 c3fd8908b9163fda2dbffe73471048bb 260 SMART SM00891 4 86 2.5E-17 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 VMUT_0289 c3fd8908b9163fda2dbffe73471048bb 260 Pfam PF02732 ERCC4 domain 7 130 9.6E-16 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 VMUT_0289 c3fd8908b9163fda2dbffe73471048bb 260 SUPERFAMILY SSF52980 2 132 7.24E-26 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 VMUT_0289 c3fd8908b9163fda2dbffe73471048bb 260 Gene3D G3DSA:3.40.50.10130 1 134 6.9E-35 T 23-10-2018 VMUT_0337 ba680b184ee37e738cb1cb53292d33e2 250 Gene3D G3DSA:1.10.3720.10 1 246 1.7E-42 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_0337 ba680b184ee37e738cb1cb53292d33e2 250 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 51 241 6.2E-12 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VMUT_0337 ba680b184ee37e738cb1cb53292d33e2 250 SUPERFAMILY SSF161098 4 238 7.06E-31 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_1817 36217eae34962019e883458012a986a9 330 SUPERFAMILY SSF56042 141 309 3.44E-33 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily VMUT_1817 36217eae34962019e883458012a986a9 330 Gene3D G3DSA:3.30.1330.10 2 138 1.3E-27 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily VMUT_1817 36217eae34962019e883458012a986a9 330 SUPERFAMILY SSF55326 3 138 7.15E-25 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily VMUT_1817 36217eae34962019e883458012a986a9 330 Gene3D G3DSA:3.90.650.10 141 315 8.6E-37 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily VMUT_1817 36217eae34962019e883458012a986a9 330 Pfam PF00586 AIR synthase related protein, N-terminal domain 32 136 1.0E-12 T 23-10-2018 IPR016188 PurM-like, N-terminal domain VMUT_1817 36217eae34962019e883458012a986a9 330 PIRSF PIRSF005644 1 325 6.7E-76 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE VMUT_1817 36217eae34962019e883458012a986a9 330 Pfam PF02769 AIR synthase related protein, C-terminal domain 147 299 1.3E-20 T 23-10-2018 IPR010918 PurM-like, C-terminal domain VMUT_1777 213f2eba9016fb7fa016e81f832fc6a8 391 Gene3D G3DSA:3.40.190.10 63 350 1.7E-61 T 23-10-2018 VMUT_1777 213f2eba9016fb7fa016e81f832fc6a8 391 Pfam PF13531 Bacterial extracellular solute-binding protein 63 350 5.3E-34 T 23-10-2018 VMUT_1777 213f2eba9016fb7fa016e81f832fc6a8 391 SUPERFAMILY SSF53850 63 363 5.43E-21 T 23-10-2018 VMUT_1777 213f2eba9016fb7fa016e81f832fc6a8 391 Gene3D G3DSA:3.40.190.10 139 314 1.7E-61 T 23-10-2018 VMUT_1305 471998910fe1db836e67493094a72f62 472 Pfam PF00083 Sugar (and other) transporter 29 462 1.2E-54 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VMUT_1305 471998910fe1db836e67493094a72f62 472 SUPERFAMILY SSF103473 13 458 2.62E-72 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_2055 009d9899941cbce91a4a4ca4470fd5fd 405 Pfam PF01926 50S ribosome-binding GTPase 8 124 2.4E-18 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 VMUT_2055 009d9899941cbce91a4a4ca4470fd5fd 405 Gene3D G3DSA:1.10.8.470 134 224 5.9E-28 T 23-10-2018 VMUT_2055 009d9899941cbce91a4a4ca4470fd5fd 405 Pfam PF08438 GTPase of unknown function C-terminal 229 336 1.1E-35 T 23-10-2018 IPR013646 Uncharacterised GTP-binding protein, C-terminal VMUT_2055 009d9899941cbce91a4a4ca4470fd5fd 405 SUPERFAMILY SSF52540 8 286 5.14E-64 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_2055 009d9899941cbce91a4a4ca4470fd5fd 405 Gene3D G3DSA:3.10.20.30 328 404 3.7E-22 T 23-10-2018 IPR012675 Beta-grasp domain superfamily VMUT_2055 009d9899941cbce91a4a4ca4470fd5fd 405 SUPERFAMILY SSF81271 331 402 1.13E-9 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 VMUT_2055 009d9899941cbce91a4a4ca4470fd5fd 405 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 81 96 1.8E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 VMUT_2055 009d9899941cbce91a4a4ca4470fd5fd 405 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 98 116 1.8E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 VMUT_2055 009d9899941cbce91a4a4ca4470fd5fd 405 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 30 48 1.8E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 VMUT_2055 009d9899941cbce91a4a4ca4470fd5fd 405 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 9 29 1.8E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 VMUT_2055 009d9899941cbce91a4a4ca4470fd5fd 405 Pfam PF02824 TGS domain 349 401 4.6E-6 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 VMUT_1262 e8de57a545a6e70379819270edf77a0b 239 Pfam PF02633 Creatinine amidohydrolase 11 225 3.7E-45 T 23-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 VMUT_1262 e8de57a545a6e70379819270edf77a0b 239 Gene3D G3DSA:3.40.50.10310 4 232 1.7E-47 T 23-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 VMUT_1262 e8de57a545a6e70379819270edf77a0b 239 SUPERFAMILY SSF102215 8 231 1.44E-49 T 23-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 VMUT_0815 96c711bd180ff21bb0a7a41539b90d00 897 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 212 892 1.1E-228 T 23-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 VMUT_0815 96c711bd180ff21bb0a7a41539b90d00 897 Pfam PF00384 Molybdopterin oxidoreductase 263 700 3.4E-91 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_0815 96c711bd180ff21bb0a7a41539b90d00 897 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 183 194 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_0815 96c711bd180ff21bb0a7a41539b90d00 897 Gene3D G3DSA:3.10.20.740 3 119 1.1E-32 T 23-10-2018 VMUT_0815 96c711bd180ff21bb0a7a41539b90d00 897 Pfam PF01568 Molydopterin dinucleotide binding domain 784 888 3.7E-24 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 VMUT_0815 96c711bd180ff21bb0a7a41539b90d00 897 Pfam PF00037 4Fe-4S binding domain 181 198 1.0E-5 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_0815 96c711bd180ff21bb0a7a41539b90d00 897 SUPERFAMILY SSF50692 739 895 1.57E-36 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily VMUT_0815 96c711bd180ff21bb0a7a41539b90d00 897 Gene3D G3DSA:2.20.25.90 208 260 3.3E-19 T 23-10-2018 VMUT_0815 96c711bd180ff21bb0a7a41539b90d00 897 Gene3D G3DSA:2.40.40.20 777 897 5.4E-34 T 23-10-2018 VMUT_0815 96c711bd180ff21bb0a7a41539b90d00 897 SUPERFAMILY SSF54292 3 116 2.23E-28 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VMUT_0815 96c711bd180ff21bb0a7a41539b90d00 897 Gene3D G3DSA:3.40.50.740 286 742 2.0E-172 T 23-10-2018 VMUT_0815 96c711bd180ff21bb0a7a41539b90d00 897 SUPERFAMILY SSF53706 187 769 1.57E-193 T 23-10-2018 VMUT_0815 96c711bd180ff21bb0a7a41539b90d00 897 Gene3D G3DSA:3.40.228.10 354 553 2.0E-172 T 23-10-2018 VMUT_0815 96c711bd180ff21bb0a7a41539b90d00 897 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 208 260 1.1E-15 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_0815 96c711bd180ff21bb0a7a41539b90d00 897 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 3 74 4.2E-15 T 23-10-2018 VMUT_0815 96c711bd180ff21bb0a7a41539b90d00 897 PIRSF PIRSF036643 1 897 0.0 T 23-10-2018 VMUT_0815 96c711bd180ff21bb0a7a41539b90d00 897 Gene3D G3DSA:3.30.70.20 122 201 3.5E-20 T 23-10-2018 VMUT_0815 96c711bd180ff21bb0a7a41539b90d00 897 SUPERFAMILY SSF54862 124 199 1.26E-15 T 23-10-2018 VMUT_0815 96c711bd180ff21bb0a7a41539b90d00 897 SMART SM00926 207 260 2.8E-18 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_1269 0ea69423671bb92d5bdb4dee6c9d9cbf 198 Gene3D G3DSA:3.30.2320.30 80 194 4.7E-18 T 23-10-2018 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 VMUT_1269 0ea69423671bb92d5bdb4dee6c9d9cbf 198 Pfam PF01991 ATP synthase (E/31 kDa) subunit 33 187 2.6E-13 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 VMUT_1269 0ea69423671bb92d5bdb4dee6c9d9cbf 198 SUPERFAMILY SSF160527 86 189 1.07E-16 T 23-10-2018 VMUT_1885 53455e482d9d2b4b40e0919ebf55efe3 201 Pfam PF06195 Protein of unknown function (DUF996) 27 187 4.9E-26 T 23-10-2018 IPR010397 Protein of unknown function DUF996 VMUT_1261 b55acb63e478ec1d25e2df7eb1da830e 189 SUPERFAMILY SSF140663 79 174 8.76E-21 T 23-10-2018 IPR023203 TTHA0068-like superfamily VMUT_1261 b55acb63e478ec1d25e2df7eb1da830e 189 Gene3D G3DSA:1.10.3450.10 67 188 8.1E-14 T 23-10-2018 VMUT_1261 b55acb63e478ec1d25e2df7eb1da830e 189 Pfam PF03745 Domain of unknown function (DUF309) 89 141 4.6E-16 T 23-10-2018 IPR005500 Protein of unknown function DUF309 VMUT_0089 17f75eb0fc047e25911b1e88431e9b4e 844 SUPERFAMILY SSF55486 217 467 3.66E-72 T 23-10-2018 VMUT_0089 17f75eb0fc047e25911b1e88431e9b4e 844 Pfam PF01433 Peptidase family M1 domain 219 457 6.9E-57 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 VMUT_0089 17f75eb0fc047e25911b1e88431e9b4e 844 Gene3D G3DSA:1.25.10.10 658 835 1.7E-19 T 23-10-2018 IPR011989 Armadillo-like helical VMUT_0089 17f75eb0fc047e25911b1e88431e9b4e 844 Pfam PF13646 HEAT repeats 716 800 3.0E-7 T 23-10-2018 VMUT_0089 17f75eb0fc047e25911b1e88431e9b4e 844 Pfam PF13646 HEAT repeats 586 662 1.4E-14 T 23-10-2018 VMUT_0089 17f75eb0fc047e25911b1e88431e9b4e 844 Gene3D G3DSA:2.60.40.1730 34 208 1.4E-28 T 23-10-2018 VMUT_0089 17f75eb0fc047e25911b1e88431e9b4e 844 SUPERFAMILY SSF48371 553 741 2.09E-26 T 23-10-2018 IPR016024 Armadillo-type fold VMUT_0089 17f75eb0fc047e25911b1e88431e9b4e 844 Gene3D G3DSA:1.25.10.110 545 643 2.5E-15 T 23-10-2018 VMUT_0089 17f75eb0fc047e25911b1e88431e9b4e 844 Gene3D G3DSA:1.10.390.60 212 462 7.2E-71 T 23-10-2018 VMUT_0089 17f75eb0fc047e25911b1e88431e9b4e 844 SMART SM00567 E-Z type HEAT repeats 664 693 4.4 T 23-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 VMUT_0089 17f75eb0fc047e25911b1e88431e9b4e 844 SMART SM00567 E-Z type HEAT repeats 729 759 270.0 T 23-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 VMUT_0089 17f75eb0fc047e25911b1e88431e9b4e 844 SMART SM00567 E-Z type HEAT repeats 598 627 4.2E-7 T 23-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 VMUT_0089 17f75eb0fc047e25911b1e88431e9b4e 844 SMART SM00567 E-Z type HEAT repeats 761 790 130.0 T 23-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 VMUT_0089 17f75eb0fc047e25911b1e88431e9b4e 844 SMART SM00567 E-Z type HEAT repeats 566 595 82.0 T 23-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 VMUT_0089 17f75eb0fc047e25911b1e88431e9b4e 844 SMART SM00567 E-Z type HEAT repeats 630 660 0.21 T 23-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 VMUT_0089 17f75eb0fc047e25911b1e88431e9b4e 844 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 192 207 4.0E-8 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 VMUT_0089 17f75eb0fc047e25911b1e88431e9b4e 844 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 331 343 4.0E-8 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 VMUT_0089 17f75eb0fc047e25911b1e88431e9b4e 844 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 312 327 4.0E-8 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 VMUT_0089 17f75eb0fc047e25911b1e88431e9b4e 844 SUPERFAMILY SSF63737 30 209 2.09E-34 T 23-10-2018 VMUT_1931 9012d57f0a1384801941367a630ce3f0 495 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 255 455 1.1E-44 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 VMUT_1931 9012d57f0a1384801941367a630ce3f0 495 SUPERFAMILY SSF56235 21 239 6.18E-21 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VMUT_1931 9012d57f0a1384801941367a630ce3f0 495 SUPERFAMILY SSF52402 252 470 2.09E-49 T 23-10-2018 VMUT_1931 9012d57f0a1384801941367a630ce3f0 495 Pfam PF13537 Glutamine amidotransferase domain 94 208 1.0E-14 T 23-10-2018 IPR017932 Glutamine amidotransferase type 2 domain VMUT_1931 9012d57f0a1384801941367a630ce3f0 495 Pfam PF06508 Queuosine biosynthesis protein QueC 254 461 1.5E-55 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 VMUT_1931 9012d57f0a1384801941367a630ce3f0 495 Gene3D G3DSA:3.40.50.620 251 471 2.1E-58 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_1931 9012d57f0a1384801941367a630ce3f0 495 Gene3D G3DSA:3.60.20.10 2 241 1.5E-23 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VMUT_1931 9012d57f0a1384801941367a630ce3f0 495 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 252 468 41.22 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 VMUT_1327 db7ca2b59be83aa432c254adc60d76f5 248 PIRSF PIRSF037724 2 241 1.3E-82 T 23-10-2018 IPR017271 Transcription regulator HTH, MJ1545, predicted VMUT_1327 db7ca2b59be83aa432c254adc60d76f5 248 Pfam PF01381 Helix-turn-helix 29 77 6.0E-9 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VMUT_1327 db7ca2b59be83aa432c254adc60d76f5 248 SUPERFAMILY SSF47413 23 77 1.8E-11 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VMUT_1327 db7ca2b59be83aa432c254adc60d76f5 248 Gene3D G3DSA:1.10.260.40 26 82 1.0E-10 T 23-10-2018 VMUT_1327 db7ca2b59be83aa432c254adc60d76f5 248 SMART SM00530 28 83 2.0E-10 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VMUT_0236 84784ae0938fd17e09616738804eaff5 135 SMART SM00240 51 101 4.8E-10 T 23-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 VMUT_0236 84784ae0938fd17e09616738804eaff5 135 Gene3D G3DSA:2.60.200.20 22 131 2.0E-23 T 23-10-2018 VMUT_0236 84784ae0938fd17e09616738804eaff5 135 Pfam PF00498 FHA domain 52 119 6.3E-16 T 23-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 VMUT_0236 84784ae0938fd17e09616738804eaff5 135 SUPERFAMILY SSF49879 51 123 1.4E-18 T 23-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 VMUT_1173 29215c75239848f165455874148bd216 343 Gene3D G3DSA:3.30.9.10 32 251 7.5E-24 T 23-10-2018 VMUT_1173 29215c75239848f165455874148bd216 343 SUPERFAMILY SSF51905 7 313 5.44E-21 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_1173 29215c75239848f165455874148bd216 343 Gene3D G3DSA:3.50.50.60 8 304 7.5E-24 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_1173 29215c75239848f165455874148bd216 343 Pfam PF01266 FAD dependent oxidoreductase 7 290 2.1E-11 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VMUT_0060 27e60dca507a6af70625f155f2bb3742 483 SUPERFAMILY SSF52402 172 330 1.28E-36 T 23-10-2018 VMUT_0060 27e60dca507a6af70625f155f2bb3742 483 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 172 363 7.3E-56 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 VMUT_0060 27e60dca507a6af70625f155f2bb3742 483 Gene3D G3DSA:3.30.2130.30 1 171 1.8E-38 T 23-10-2018 VMUT_0060 27e60dca507a6af70625f155f2bb3742 483 Pfam PF00581 Rhodanese-like domain 407 471 3.8E-6 T 23-10-2018 IPR001763 Rhodanese-like domain VMUT_0060 27e60dca507a6af70625f155f2bb3742 483 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 4 363 4.6E-87 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 VMUT_0060 27e60dca507a6af70625f155f2bb3742 483 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 483 130.398 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 VMUT_0060 27e60dca507a6af70625f155f2bb3742 483 SMART SM00450 393 478 0.0032 T 23-10-2018 IPR001763 Rhodanese-like domain VMUT_0060 27e60dca507a6af70625f155f2bb3742 483 Gene3D G3DSA:3.40.250.10 394 475 2.1E-14 T 23-10-2018 IPR036873 Rhodanese-like domain superfamily VMUT_0060 27e60dca507a6af70625f155f2bb3742 483 Pfam PF02926 THUMP domain 39 160 6.0E-19 T 23-10-2018 IPR004114 THUMP domain GO:0003723 VMUT_0060 27e60dca507a6af70625f155f2bb3742 483 SMART SM00981 74 162 1.3E-21 T 23-10-2018 IPR004114 THUMP domain GO:0003723 VMUT_0060 27e60dca507a6af70625f155f2bb3742 483 SUPERFAMILY SSF143437 1 170 5.06E-42 T 23-10-2018 VMUT_0060 27e60dca507a6af70625f155f2bb3742 483 Gene3D G3DSA:3.40.50.620 172 379 9.7E-50 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_0060 27e60dca507a6af70625f155f2bb3742 483 SUPERFAMILY SSF52821 405 471 6.02E-17 T 23-10-2018 IPR036873 Rhodanese-like domain superfamily VMUT_1089 2ad2139ccb5cb9d39b601e263d17782f 383 SUPERFAMILY SSF53756 3 372 2.04E-42 T 23-10-2018 VMUT_1089 2ad2139ccb5cb9d39b601e263d17782f 383 Gene3D G3DSA:3.40.50.2000 1 192 3.3E-9 T 23-10-2018 VMUT_1089 2ad2139ccb5cb9d39b601e263d17782f 383 Pfam PF13692 Glycosyl transferases group 1 203 341 4.1E-13 T 23-10-2018 VMUT_1089 2ad2139ccb5cb9d39b601e263d17782f 383 Gene3D G3DSA:3.40.50.2000 201 365 1.0E-21 T 23-10-2018 VMUT_2220 95efdb9e51a0c990cd1d8dec0b01dd91 318 Gene3D G3DSA:3.40.50.720 4 316 1.6E-35 T 23-10-2018 VMUT_2220 95efdb9e51a0c990cd1d8dec0b01dd91 318 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 185 1.4E-19 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 VMUT_2220 95efdb9e51a0c990cd1d8dec0b01dd91 318 SUPERFAMILY SSF51735 4 316 2.39E-36 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0433 8906bf26ae77ffeb0b1a7438b0bd0c2a 296 Pfam PF00795 Carbon-nitrogen hydrolase 6 251 4.1E-49 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 VMUT_0433 8906bf26ae77ffeb0b1a7438b0bd0c2a 296 SUPERFAMILY SSF56317 2 260 7.98E-73 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily VMUT_0433 8906bf26ae77ffeb0b1a7438b0bd0c2a 296 Gene3D G3DSA:3.60.110.10 1 270 4.7E-67 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily VMUT_0966 2028b99160e180c5f8124083392963be 317 Gene3D G3DSA:2.170.120.12 56 171 9.3E-77 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_0966 2028b99160e180c5f8124083392963be 317 Hamap MF_00320 DNA-directed RNA polymerase subunit D [rpoD]. 19 281 30.802 T 23-10-2018 IPR022842 DNA-directed RNA polymerase subunit D (Rpo3) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_0966 2028b99160e180c5f8124083392963be 317 Gene3D G3DSA:3.30.70.3110 181 242 9.3E-77 T 23-10-2018 VMUT_0966 2028b99160e180c5f8124083392963be 317 SUPERFAMILY SSF56553 55 172 1.59E-29 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_0966 2028b99160e180c5f8124083392963be 317 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 63 172 2.4E-26 T 23-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_0966 2028b99160e180c5f8124083392963be 317 Gene3D G3DSA:3.30.1360.10 22 275 9.3E-77 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_0966 2028b99160e180c5f8124083392963be 317 SMART SM00662 30 278 1.7E-62 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_0966 2028b99160e180c5f8124083392963be 317 SUPERFAMILY SSF55257 21 280 2.55E-23 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_0966 2028b99160e180c5f8124083392963be 317 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 35 272 1.4E-13 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_0966 2028b99160e180c5f8124083392963be 317 ProSitePatterns PS00446 RNA polymerases D / 30 to 40 Kd subunits signature. 44 84 - T 23-10-2018 IPR001514 DNA-directed RNA polymerase, 30-40kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 VMUT_0568 9d964d56ac3fc120fd3c51bcd15275fa 152 Pfam PF04173 TQO small subunit DoxD 1 152 2.7E-49 T 23-10-2018 IPR007301 TQO small subunit DoxD KEGG: 00920+1.8.5.2|MetaCyc: PWY-5303 VMUT_0304 5ad4263a61ee090c10bdd6fb2c9e3ebc 180 Gene3D G3DSA:2.60.40.790 82 170 4.1E-23 T 23-10-2018 IPR008978 HSP20-like chaperone VMUT_0304 5ad4263a61ee090c10bdd6fb2c9e3ebc 180 Pfam PF00011 Hsp20/alpha crystallin family 93 174 4.1E-10 T 23-10-2018 IPR002068 Alpha crystallin/Hsp20 domain VMUT_0304 5ad4263a61ee090c10bdd6fb2c9e3ebc 180 SUPERFAMILY SSF49764 86 178 5.89E-19 T 23-10-2018 IPR008978 HSP20-like chaperone VMUT_1561 99f0d285163192e01314c3dc9a5864fb 998 Hamap MF_00049_A Leucine--tRNA ligase [leuS]. 4 992 15.995 T 23-10-2018 IPR020791 Leucine-tRNA ligase, archaeal GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4 VMUT_1561 99f0d285163192e01314c3dc9a5864fb 998 TIGRFAM TIGR00395 leuS_arch: leucine--tRNA ligase 6 992 0.0 T 23-10-2018 IPR004493 Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 VMUT_1561 99f0d285163192e01314c3dc9a5864fb 998 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 11 692 8.6E-65 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_1561 99f0d285163192e01314c3dc9a5864fb 998 Pfam PF08264 Anticodon-binding domain of tRNA 740 874 1.2E-19 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 VMUT_1561 99f0d285163192e01314c3dc9a5864fb 998 Gene3D G3DSA:1.10.10.720 880 938 2.6E-25 T 23-10-2018 VMUT_1561 99f0d285163192e01314c3dc9a5864fb 998 Gene3D G3DSA:3.90.740.10 208 448 3.8E-267 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 VMUT_1561 99f0d285163192e01314c3dc9a5864fb 998 SUPERFAMILY SSF50677 214 438 1.74E-39 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 VMUT_1561 99f0d285163192e01314c3dc9a5864fb 998 SUPERFAMILY SSF52374 4 705 1.0E-89 T 23-10-2018 VMUT_1561 99f0d285163192e01314c3dc9a5864fb 998 Gene3D G3DSA:1.10.730.10 699 825 2.3E-18 T 23-10-2018 VMUT_1561 99f0d285163192e01314c3dc9a5864fb 998 SUPERFAMILY SSF47323 729 898 1.61E-27 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_1561 99f0d285163192e01314c3dc9a5864fb 998 Gene3D G3DSA:3.40.50.620 7 697 3.8E-267 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_1561 99f0d285163192e01314c3dc9a5864fb 998 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 50 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_1561 99f0d285163192e01314c3dc9a5864fb 998 Gene3D G3DSA:3.30.2320.20 852 992 2.6E-25 T 23-10-2018 VMUT_0875 579aa785c351145fed1a1848620e8ab4 268 SUPERFAMILY SSF101852 165 265 1.57E-22 T 23-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal VMUT_0875 579aa785c351145fed1a1848620e8ab4 268 SUPERFAMILY SSF102522 3 155 5.36E-62 T 23-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal VMUT_0875 579aa785c351145fed1a1848620e8ab4 268 PIRSF PIRSF006779 1 267 2.2E-90 T 23-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase VMUT_0875 579aa785c351145fed1a1848620e8ab4 268 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 5 262 3.6E-81 T 23-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase VMUT_0875 579aa785c351145fed1a1848620e8ab4 268 Gene3D G3DSA:2.40.30.90 163 267 1.1E-23 T 23-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal VMUT_0875 579aa785c351145fed1a1848620e8ab4 268 Gene3D G3DSA:3.40.50.10790 1 159 1.1E-65 T 23-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal VMUT_0075 9c7283f37695ba070c85a9a88aaa51a9 305 Pfam PF12644 Protein of unknown function (DUF3782) 152 230 3.2E-21 T 23-10-2018 IPR024271 Protein of unknown function DUF3782 VMUT_0075 9c7283f37695ba070c85a9a88aaa51a9 305 SUPERFAMILY SSF52980 83 300 9.65E-8 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 VMUT_0075 9c7283f37695ba070c85a9a88aaa51a9 305 Pfam PF07788 PD-(D/E)XK nuclease superfamily 232 299 1.9E-26 T 23-10-2018 IPR012431 PD-(D/E)XK nuclease VMUT_1646 5a2ee24157d79314887ea72e6aa3a182 292 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 19 100 3.9E-8 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis VMUT_1646 5a2ee24157d79314887ea72e6aa3a182 292 SUPERFAMILY SSF53335 114 285 6.23E-31 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_1646 5a2ee24157d79314887ea72e6aa3a182 292 Gene3D G3DSA:3.30.420.130 1 123 5.9E-33 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily VMUT_1646 5a2ee24157d79314887ea72e6aa3a182 292 Gene3D G3DSA:3.40.50.150 124 290 1.7E-38 T 23-10-2018 VMUT_1646 5a2ee24157d79314887ea72e6aa3a182 292 Pfam PF08241 Methyltransferase domain 149 242 5.9E-21 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 VMUT_1646 5a2ee24157d79314887ea72e6aa3a182 292 SUPERFAMILY SSF53146 1 118 1.09E-19 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily VMUT_0659 a1f0ad6a3b6631f13b48f36c8f156bc8 283 Gene3D G3DSA:3.40.50.10880 136 276 2.5E-28 T 23-10-2018 VMUT_0659 a1f0ad6a3b6631f13b48f36c8f156bc8 283 Pfam PF01937 Protein of unknown function DUF89 58 269 6.1E-17 T 23-10-2018 IPR002791 Domain of unknown function DUF89 VMUT_0659 a1f0ad6a3b6631f13b48f36c8f156bc8 283 SUPERFAMILY SSF111321 11 274 1.96E-45 T 23-10-2018 IPR036075 AF1104-like superfamily VMUT_0659 a1f0ad6a3b6631f13b48f36c8f156bc8 283 PIRSF PIRSF006593 9 278 2.8E-32 T 23-10-2018 IPR014444 Uncharacterised conserved protein UCP006593 VMUT_1345 18135bfd70e2d3472f901cf69305da24 133 SUPERFAMILY SSF81301 10 105 4.0E-11 T 23-10-2018 VMUT_1345 18135bfd70e2d3472f901cf69305da24 133 Pfam PF01909 Nucleotidyltransferase domain 21 102 1.5E-5 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 VMUT_1345 18135bfd70e2d3472f901cf69305da24 133 Gene3D G3DSA:3.30.460.10 10 102 2.3E-12 T 23-10-2018 VMUT_0280 e914c08612ca2a8b1b0b2e2fdf4aa76d 409 Gene3D G3DSA:3.40.50.360 258 404 1.0E-26 T 23-10-2018 IPR029039 Flavoprotein-like superfamily VMUT_0280 e914c08612ca2a8b1b0b2e2fdf4aa76d 409 SUPERFAMILY SSF56281 37 284 2.36E-38 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_0280 e914c08612ca2a8b1b0b2e2fdf4aa76d 409 SMART SM00849 43 235 1.5E-21 T 23-10-2018 IPR001279 Metallo-beta-lactamase VMUT_0280 e914c08612ca2a8b1b0b2e2fdf4aa76d 409 Gene3D G3DSA:3.60.15.10 2 256 1.1E-76 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_0280 e914c08612ca2a8b1b0b2e2fdf4aa76d 409 SUPERFAMILY SSF52218 260 406 8.17E-22 T 23-10-2018 IPR029039 Flavoprotein-like superfamily VMUT_1229 a0503943c77865834f6310aeb60c752a 297 SUPERFAMILY SSF51556 9 296 6.04E-28 T 23-10-2018 IPR032466 Metal-dependent hydrolase VMUT_1229 a0503943c77865834f6310aeb60c752a 297 PIRSF PIRSF021898 2 297 3.7E-61 T 23-10-2018 IPR016797 Uncharacterised conserved protein UCP021898 VMUT_1229 a0503943c77865834f6310aeb60c752a 297 Gene3D G3DSA:3.20.20.140 161 297 2.5E-7 T 23-10-2018 VMUT_0116 079e56278724d2b244bc46704bdab212 241 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 7 229 2.1E-47 T 23-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 VMUT_0116 079e56278724d2b244bc46704bdab212 241 SUPERFAMILY SSF51695 2 235 8.37E-76 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 VMUT_0116 079e56278724d2b244bc46704bdab212 241 Gene3D G3DSA:3.20.20.190 1 238 9.9E-85 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 VMUT_2252 14d3db18664cd29831e2825d0e61c82e 525 Gene3D G3DSA:3.40.50.12780 10 411 4.2E-66 T 23-10-2018 VMUT_2252 14d3db18664cd29831e2825d0e61c82e 525 Pfam PF13193 AMP-binding enzyme C-terminal domain 426 510 9.7E-15 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VMUT_2252 14d3db18664cd29831e2825d0e61c82e 525 SUPERFAMILY SSF56801 13 523 3.92E-93 T 23-10-2018 VMUT_2252 14d3db18664cd29831e2825d0e61c82e 525 ProSitePatterns PS00455 Putative AMP-binding domain signature. 141 152 - T 23-10-2018 IPR020845 AMP-binding, conserved site VMUT_2252 14d3db18664cd29831e2825d0e61c82e 525 Pfam PF00501 AMP-binding enzyme 13 416 9.6E-52 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VMUT_2252 14d3db18664cd29831e2825d0e61c82e 525 Gene3D G3DSA:3.30.300.310 412 525 7.6E-28 T 23-10-2018 VMUT_0516 d20cfe5e5ca15837b9e0e1f84bd1071f 404 SUPERFAMILY SSF53335 15 398 9.75E-55 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_0516 d20cfe5e5ca15837b9e0e1f84bd1071f 404 SMART SM00359 98 172 3.8E-10 T 23-10-2018 IPR002478 PUA domain GO:0003723 VMUT_0516 d20cfe5e5ca15837b9e0e1f84bd1071f 404 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 85 168 4.9E-11 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 VMUT_0516 d20cfe5e5ca15837b9e0e1f84bd1071f 404 Gene3D G3DSA:3.30.70.1170 40 97 1.6E-6 T 23-10-2018 VMUT_0516 d20cfe5e5ca15837b9e0e1f84bd1071f 404 Gene3D G3DSA:3.40.50.150 196 404 1.0E-54 T 23-10-2018 VMUT_0516 d20cfe5e5ca15837b9e0e1f84bd1071f 404 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 381 398 2.1E-22 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase VMUT_0516 d20cfe5e5ca15837b9e0e1f84bd1071f 404 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 211 221 2.1E-22 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase VMUT_0516 d20cfe5e5ca15837b9e0e1f84bd1071f 404 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 182 196 2.1E-22 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase VMUT_0516 d20cfe5e5ca15837b9e0e1f84bd1071f 404 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 329 345 2.1E-22 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase VMUT_0516 d20cfe5e5ca15837b9e0e1f84bd1071f 404 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 282 294 2.1E-22 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase VMUT_0516 d20cfe5e5ca15837b9e0e1f84bd1071f 404 Pfam PF01189 16S rRNA methyltransferase RsmB/F 201 397 2.7E-42 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 VMUT_0516 d20cfe5e5ca15837b9e0e1f84bd1071f 404 Gene3D G3DSA:2.30.130.10 98 174 2.7E-17 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 VMUT_0516 d20cfe5e5ca15837b9e0e1f84bd1071f 404 Pfam PF01472 PUA domain 99 167 2.2E-16 T 23-10-2018 IPR002478 PUA domain GO:0003723 VMUT_0516 d20cfe5e5ca15837b9e0e1f84bd1071f 404 SUPERFAMILY SSF88697 98 168 7.18E-17 T 23-10-2018 IPR015947 PUA-like superfamily VMUT_0257 bda74c141d2211b5181a5aa122ef7549 198 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 118 124 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 VMUT_0257 bda74c141d2211b5181a5aa122ef7549 198 Gene3D G3DSA:3.40.50.150 33 198 3.8E-23 T 23-10-2018 VMUT_0257 bda74c141d2211b5181a5aa122ef7549 198 Pfam PF01555 DNA methylase 43 90 1.2E-8 T 23-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 VMUT_0257 bda74c141d2211b5181a5aa122ef7549 198 SUPERFAMILY SSF53335 41 170 2.94E-22 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_0751 c10948f170e43c067dffcd9d9ba45780 133 Hamap MF_00029 30S ribosomal protein S8e [rps8e]. 6 132 28.944 T 23-10-2018 IPR020919 Ribosomal protein S8e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_0751 c10948f170e43c067dffcd9d9ba45780 133 TIGRFAM TIGR00307 eS8: ribosomal protein eS8 7 132 2.9E-33 T 23-10-2018 IPR001047 Ribosomal protein S8e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0751 c10948f170e43c067dffcd9d9ba45780 133 Pfam PF01201 Ribosomal protein S8e 9 131 1.6E-26 T 23-10-2018 IPR022309 Ribosomal protein S8e/ribosomal biogenesis NSA2 VMUT_0751 c10948f170e43c067dffcd9d9ba45780 133 Gene3D G3DSA:2.40.10.310 64 133 7.7E-30 T 23-10-2018 VMUT_0025 3dbab0fe6b0c36f34af6a622787369ce 329 Gene3D G3DSA:3.40.47.10 2 329 3.4E-57 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_0025 3dbab0fe6b0c36f34af6a622787369ce 329 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 105 185 2.2E-12 T 23-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 VMUT_0025 3dbab0fe6b0c36f34af6a622787369ce 329 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 240 326 3.5E-19 T 23-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 VMUT_0025 3dbab0fe6b0c36f34af6a622787369ce 329 SUPERFAMILY SSF53901 5 327 1.26E-27 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_2112 1084ba80eccad386ada73d7859c3b71a 274 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 3 242 2.2E-55 T 23-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 VMUT_2112 1084ba80eccad386ada73d7859c3b71a 274 Gene3D G3DSA:3.40.1210.10 2 273 6.8E-91 T 23-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 VMUT_2112 1084ba80eccad386ada73d7859c3b71a 274 Pfam PF01975 Survival protein SurE 4 190 1.1E-46 T 23-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 VMUT_2112 1084ba80eccad386ada73d7859c3b71a 274 SUPERFAMILY SSF64167 3 251 6.54E-69 T 23-10-2018 VMUT_2112 1084ba80eccad386ada73d7859c3b71a 274 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 2 265 30.308 T 23-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 VMUT_1785 78715dffdd00461314d994f1f087fdac 296 TIGRFAM TIGR00501 met_pdase_II: methionine aminopeptidase, type II 6 285 4.8E-90 T 23-10-2018 IPR002468 Peptidase M24A, methionine aminopeptidase, subfamily 2 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800|Reactome: R-HSA-2514859 VMUT_1785 78715dffdd00461314d994f1f087fdac 296 SUPERFAMILY SSF55920 4 286 6.8E-61 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like VMUT_1785 78715dffdd00461314d994f1f087fdac 296 ProSitePatterns PS01202 Methionine aminopeptidase subfamily 2 signature. 75 91 - T 23-10-2018 IPR018349 Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site MetaCyc: PWY-7799|MetaCyc: PWY-7800 VMUT_1785 78715dffdd00461314d994f1f087fdac 296 Gene3D G3DSA:3.90.230.10 8 280 7.9E-90 T 23-10-2018 VMUT_1785 78715dffdd00461314d994f1f087fdac 296 Gene3D G3DSA:1.10.10.10 192 266 7.9E-90 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_1785 78715dffdd00461314d994f1f087fdac 296 PRINTS PR00599 Methionine aminopeptidase-1 signature 50 63 3.7E-14 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 VMUT_1785 78715dffdd00461314d994f1f087fdac 296 PRINTS PR00599 Methionine aminopeptidase-1 signature 75 91 3.7E-14 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 VMUT_1785 78715dffdd00461314d994f1f087fdac 296 PRINTS PR00599 Methionine aminopeptidase-1 signature 173 185 3.7E-14 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 VMUT_1785 78715dffdd00461314d994f1f087fdac 296 PRINTS PR00599 Methionine aminopeptidase-1 signature 142 154 3.7E-14 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 VMUT_1785 78715dffdd00461314d994f1f087fdac 296 Pfam PF00557 Metallopeptidase family M24 5 281 1.5E-37 T 23-10-2018 IPR000994 Peptidase M24 VMUT_1785 78715dffdd00461314d994f1f087fdac 296 SUPERFAMILY SSF46785 196 264 2.99E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_1785 78715dffdd00461314d994f1f087fdac 296 Hamap MF_01975 Methionine aminopeptidase [map]. 1 289 44.698 T 23-10-2018 IPR028595 Methionine aminopeptidase, archaeal GO:0004177|GO:0006508 MetaCyc: PWY-7799|MetaCyc: PWY-7800 VMUT_0202 35b1edc2869991d8096a76e5753b0cc7 85 SUPERFAMILY SSF57850 37 70 4.71E-5 T 23-10-2018 VMUT_0132 b48fc1c12e657cf2841fe377e4ae1061 256 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 256 22.678 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 VMUT_0132 b48fc1c12e657cf2841fe377e4ae1061 256 Pfam PF02654 Cobalamin-5-phosphate synthase 14 245 2.4E-31 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 VMUT_0132 b48fc1c12e657cf2841fe377e4ae1061 256 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 7 245 4.0E-33 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 VMUT_1536 bba3be951641854f034e0fd7e6d5dc04 440 SUPERFAMILY SSF51569 40 338 4.21E-56 T 23-10-2018 VMUT_1536 bba3be951641854f034e0fd7e6d5dc04 440 Gene3D G3DSA:3.20.20.70 38 320 3.4E-61 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_1536 bba3be951641854f034e0fd7e6d5dc04 440 Gene3D G3DSA:1.10.238.260 327 438 1.8E-20 T 23-10-2018 VMUT_1536 bba3be951641854f034e0fd7e6d5dc04 440 Pfam PF00682 HMGL-like 45 299 1.0E-35 T 23-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 VMUT_1694 e0e4efcdbddea775dccb50635c788d05 289 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VMUT_1694 e0e4efcdbddea775dccb50635c788d05 289 SMART SM00382 28 211 3.0E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_1694 e0e4efcdbddea775dccb50635c788d05 289 SUPERFAMILY SSF52540 4 230 5.43E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1694 e0e4efcdbddea775dccb50635c788d05 289 Gene3D G3DSA:3.40.50.300 1 233 8.4E-60 T 23-10-2018 VMUT_1694 e0e4efcdbddea775dccb50635c788d05 289 Pfam PF00005 ABC transporter 19 162 1.5E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_1165 33aded8a4c402c0e31f7a4726dc14ae0 539 Pfam PF01144 Coenzyme A transferase 9 248 4.6E-22 T 23-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 VMUT_1165 33aded8a4c402c0e31f7a4726dc14ae0 539 SUPERFAMILY SSF100950 2 265 1.67E-54 T 23-10-2018 IPR037171 NagB/RpiA transferase-like VMUT_1165 33aded8a4c402c0e31f7a4726dc14ae0 539 SUPERFAMILY SSF100950 306 531 1.74E-53 T 23-10-2018 IPR037171 NagB/RpiA transferase-like VMUT_1165 33aded8a4c402c0e31f7a4726dc14ae0 539 PIRSF PIRSF000858 1 536 1.6E-172 T 23-10-2018 IPR014388 3-oxoacid CoA-transferase GO:0008410|GO:0046952 Reactome: R-HSA-77108 VMUT_1165 33aded8a4c402c0e31f7a4726dc14ae0 539 Gene3D G3DSA:3.40.1080.10 1 273 3.7E-72 T 23-10-2018 VMUT_1165 33aded8a4c402c0e31f7a4726dc14ae0 539 Gene3D G3DSA:3.40.1080.10 284 535 1.6E-80 T 23-10-2018 VMUT_1165 33aded8a4c402c0e31f7a4726dc14ae0 539 SMART SM00882 4 249 6.8E-23 T 23-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 VMUT_0034 327f0754d6a8bd84f2b816d6bb1f364f 296 Pfam PF01972 Serine dehydrogenase proteinase 4 283 2.6E-124 T 23-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 VMUT_0034 327f0754d6a8bd84f2b816d6bb1f364f 296 SUPERFAMILY SSF52096 54 246 2.58E-28 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VMUT_0034 327f0754d6a8bd84f2b816d6bb1f364f 296 Gene3D G3DSA:3.90.226.10 58 246 2.1E-22 T 23-10-2018 VMUT_1606 b0399c128aa2faad34111fb960dea574 144 Gene3D G3DSA:1.10.10.10 4 104 2.2E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_1606 b0399c128aa2faad34111fb960dea574 144 SUPERFAMILY SSF46785 12 89 2.22E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0892 93c5dc8d8f8a212935224df7bc6bb901 318 Pfam PF00107 Zinc-binding dehydrogenase 164 281 2.2E-17 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 VMUT_0892 93c5dc8d8f8a212935224df7bc6bb901 318 SUPERFAMILY SSF51735 127 286 2.03E-31 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0892 93c5dc8d8f8a212935224df7bc6bb901 318 SMART SM00829 10 316 1.4E-7 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VMUT_0892 93c5dc8d8f8a212935224df7bc6bb901 318 SUPERFAMILY SSF50129 5 160 6.18E-39 T 23-10-2018 IPR011032 GroES-like superfamily VMUT_0892 93c5dc8d8f8a212935224df7bc6bb901 318 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 122 8.1E-20 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VMUT_0892 93c5dc8d8f8a212935224df7bc6bb901 318 Gene3D G3DSA:3.90.180.10 3 318 9.9E-80 T 23-10-2018 VMUT_1531 c95739472314ac351179b66924038f8d 407 Gene3D G3DSA:3.40.50.1100 59 376 1.4E-115 T 23-10-2018 VMUT_1531 c95739472314ac351179b66924038f8d 407 TIGRFAM TIGR00260 thrC: threonine synthase 57 377 5.0E-78 T 23-10-2018 IPR004450 Threonine synthase-like VMUT_1531 c95739472314ac351179b66924038f8d 407 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 72 370 6.1E-67 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme VMUT_1531 c95739472314ac351179b66924038f8d 407 PIRSF PIRSF038945 42 400 9.8E-122 T 23-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 VMUT_1531 c95739472314ac351179b66924038f8d 407 SUPERFAMILY SSF53686 8 381 6.55E-101 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme VMUT_1531 c95739472314ac351179b66924038f8d 407 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 94 107 - T 23-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 VMUT_1531 c95739472314ac351179b66924038f8d 407 Gene3D G3DSA:3.40.50.1100 102 204 1.4E-115 T 23-10-2018 VMUT_1331 86e331c243d07f07ead46be1d1de133e 392 Gene3D G3DSA:3.40.640.10 20 265 3.8E-95 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VMUT_1331 86e331c243d07f07ead46be1d1de133e 392 Pfam PF00266 Aminotransferase class-V 11 342 1.9E-24 T 23-10-2018 IPR000192 Aminotransferase class V domain VMUT_1331 86e331c243d07f07ead46be1d1de133e 392 SUPERFAMILY SSF53383 9 365 7.17E-81 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VMUT_1331 86e331c243d07f07ead46be1d1de133e 392 PIRSF PIRSF000524 3 381 2.0E-95 T 23-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 VMUT_1331 86e331c243d07f07ead46be1d1de133e 392 Gene3D G3DSA:3.90.1150.10 15 366 3.8E-95 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VMUT_1439 71ba0caa3d4420e21236723195a4a395 506 PIRSF PIRSF006060 4 499 7.7E-33 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_1439 71ba0caa3d4420e21236723195a4a395 506 Pfam PF13520 Amino acid permease 32 448 2.4E-19 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_1439 71ba0caa3d4420e21236723195a4a395 506 Gene3D G3DSA:1.20.1740.10 16 494 1.1E-12 T 23-10-2018 VMUT_0594 30bac3cf808fa33a47191afdc438a712 220 SUPERFAMILY SSF116726 145 216 1.7E-7 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 VMUT_0594 30bac3cf808fa33a47191afdc438a712 220 Gene3D G3DSA:3.40.50.720 4 135 3.5E-29 T 23-10-2018 VMUT_0594 30bac3cf808fa33a47191afdc438a712 220 Gene3D G3DSA:3.30.70.1450 147 216 2.6E-6 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 VMUT_0594 30bac3cf808fa33a47191afdc438a712 220 PRINTS PR00335 TrkA potassium uptake protein signature 51 61 2.9E-8 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 VMUT_0594 30bac3cf808fa33a47191afdc438a712 220 PRINTS PR00335 TrkA potassium uptake protein signature 62 72 2.9E-8 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 VMUT_0594 30bac3cf808fa33a47191afdc438a712 220 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 2.9E-8 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 VMUT_0594 30bac3cf808fa33a47191afdc438a712 220 PRINTS PR00335 TrkA potassium uptake protein signature 75 89 2.9E-8 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 VMUT_0594 30bac3cf808fa33a47191afdc438a712 220 PRINTS PR00335 TrkA potassium uptake protein signature 3 17 2.9E-8 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 VMUT_0594 30bac3cf808fa33a47191afdc438a712 220 SUPERFAMILY SSF51735 5 141 7.62E-25 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0594 30bac3cf808fa33a47191afdc438a712 220 Pfam PF02254 TrkA-N domain 5 118 1.7E-23 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 VMUT_0395 37f68430edf6e147d380d94bd6313c95 249 SUPERFAMILY SSF46785 5 94 1.27E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0395 37f68430edf6e147d380d94bd6313c95 249 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 14 78 5.6E-19 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal VMUT_0395 37f68430edf6e147d380d94bd6313c95 249 Gene3D G3DSA:1.10.10.10 1 103 3.8E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_1971 fdc789281cf786ff8eec5d4325843818 203 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 203 24.073 T 23-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VMUT_1971 fdc789281cf786ff8eec5d4325843818 203 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 12 171 4.7E-43 T 23-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VMUT_1971 fdc789281cf786ff8eec5d4325843818 203 SUPERFAMILY SSF53271 5 195 2.49E-47 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like VMUT_1971 fdc789281cf786ff8eec5d4325843818 203 Gene3D G3DSA:3.40.50.2020 1 201 1.8E-63 T 23-10-2018 VMUT_1971 fdc789281cf786ff8eec5d4325843818 203 Pfam PF00156 Phosphoribosyl transferase domain 44 153 3.1E-18 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 VMUT_0251 f0c16de80033ed9c2b7d609672a08227 97 SUPERFAMILY SSF160363 3 88 7.98E-29 T 23-10-2018 IPR023129 MTH889-like domain superfamily VMUT_0251 f0c16de80033ed9c2b7d609672a08227 97 ProDom PD012512 ARCHAEA PH1931 STS176 TA1183 MJ0319 PRECURSOR TVG0378908 UNCHARACTERIZED DUF211 AF1549 57 88 9.0E-4 T 23-10-2018 IPR003831 Protein of unknown function DUF211 VMUT_0251 f0c16de80033ed9c2b7d609672a08227 97 Pfam PF02680 Uncharacterized ArCR, COG1888 4 88 3.9E-31 T 23-10-2018 IPR003831 Protein of unknown function DUF211 VMUT_0251 f0c16de80033ed9c2b7d609672a08227 97 Gene3D G3DSA:3.30.70.1340 1 86 4.2E-29 T 23-10-2018 IPR023129 MTH889-like domain superfamily VMUT_1161 cb98f948155e317e8b7ca157e7052b32 246 Pfam PF02566 OsmC-like protein 143 245 1.7E-22 T 23-10-2018 IPR003718 OsmC/Ohr family VMUT_1161 cb98f948155e317e8b7ca157e7052b32 246 Gene3D G3DSA:3.30.559.10 11 101 4.7E-32 T 23-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 VMUT_1161 cb98f948155e317e8b7ca157e7052b32 246 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 13 100 1.2E-30 T 23-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 VMUT_1161 cb98f948155e317e8b7ca157e7052b32 246 Gene3D G3DSA:3.30.300.20 103 239 2.6E-36 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta VMUT_1161 cb98f948155e317e8b7ca157e7052b32 246 SUPERFAMILY SSF82784 107 245 1.13E-34 T 23-10-2018 IPR036102 OsmC/Ohr superfamily VMUT_1161 cb98f948155e317e8b7ca157e7052b32 246 SUPERFAMILY SSF52777 13 99 1.16E-32 T 23-10-2018 VMUT_2092 b86c9cb9bdb43106ebc3fc214489f7a1 223 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 6 208 1.4E-52 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VMUT_2092 b86c9cb9bdb43106ebc3fc214489f7a1 223 ProSitePatterns PS00171 Triosephosphate isomerase active site. 139 149 - T 23-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VMUT_2092 b86c9cb9bdb43106ebc3fc214489f7a1 223 Hamap MF_00147_A Triosephosphate isomerase [tpiA]. 3 222 38.779 T 23-10-2018 IPR022891 Triosephosphate isomerase, archaeal GO:0004807|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003 VMUT_2092 b86c9cb9bdb43106ebc3fc214489f7a1 223 Pfam PF05690 Thiazole biosynthesis protein ThiG 145 213 8.6E-8 T 23-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 VMUT_2092 b86c9cb9bdb43106ebc3fc214489f7a1 223 Pfam PF00121 Triosephosphate isomerase 5 103 2.0E-9 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VMUT_2092 b86c9cb9bdb43106ebc3fc214489f7a1 223 Gene3D G3DSA:3.20.20.70 1 223 6.3E-84 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_2092 b86c9cb9bdb43106ebc3fc214489f7a1 223 SUPERFAMILY SSF51351 1 222 1.11E-47 T 23-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VMUT_1872 271765de1e8954a2de8ff5639f1f0e76 189 Pfam PF06197 Protein of unknown function (DUF998) 15 177 7.7E-19 T 23-10-2018 IPR009339 Protein of unknown function DUF998 VMUT_0310 7e821a8fa73a66fc594c2cf890887535 301 Gene3D G3DSA:3.90.420.10 72 300 1.9E-49 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 VMUT_0310 7e821a8fa73a66fc594c2cf890887535 301 Pfam PF00174 Oxidoreductase molybdopterin binding domain 139 287 1.3E-40 T 23-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 VMUT_0310 7e821a8fa73a66fc594c2cf890887535 301 SUPERFAMILY SSF56524 123 293 5.23E-58 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 VMUT_1707 09d7402622421db090c6a5ff9337c920 345 Pfam PF12644 Protein of unknown function (DUF3782) 185 261 5.0E-25 T 23-10-2018 IPR024271 Protein of unknown function DUF3782 VMUT_1707 09d7402622421db090c6a5ff9337c920 345 Pfam PF07788 PD-(D/E)XK nuclease superfamily 262 335 4.7E-20 T 23-10-2018 IPR012431 PD-(D/E)XK nuclease VMUT_1707 09d7402622421db090c6a5ff9337c920 345 SUPERFAMILY SSF58104 39 158 3.79E-6 T 23-10-2018 VMUT_0254 115ec09c0164ec723f10fd5f96d09146 586 SUPERFAMILY SSF51905 2 424 5.05E-70 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0254 115ec09c0164ec723f10fd5f96d09146 586 Gene3D G3DSA:4.10.80.40 549 582 1.7E-9 T 23-10-2018 VMUT_0254 115ec09c0164ec723f10fd5f96d09146 586 SUPERFAMILY SSF56425 232 354 3.44E-42 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 VMUT_0254 115ec09c0164ec723f10fd5f96d09146 586 PIRSF PIRSF000171 1 584 7.7E-47 T 23-10-2018 VMUT_0254 115ec09c0164ec723f10fd5f96d09146 586 Pfam PF00890 FAD binding domain 8 400 1.2E-108 T 23-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 VMUT_0254 115ec09c0164ec723f10fd5f96d09146 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 2.8E-5 T 23-10-2018 VMUT_0254 115ec09c0164ec723f10fd5f96d09146 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 363 385 2.8E-5 T 23-10-2018 VMUT_0254 115ec09c0164ec723f10fd5f96d09146 586 Pfam PF02910 Fumarate reductase flavoprotein C-term 461 586 1.5E-41 T 23-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VMUT_0254 115ec09c0164ec723f10fd5f96d09146 586 Gene3D G3DSA:3.90.700.10 242 348 2.2E-145 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 VMUT_0254 115ec09c0164ec723f10fd5f96d09146 586 SUPERFAMILY SSF46977 453 586 5.63E-51 T 23-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VMUT_0254 115ec09c0164ec723f10fd5f96d09146 586 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 8 586 4.3E-233 T 23-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VMUT_0254 115ec09c0164ec723f10fd5f96d09146 586 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 45 54 - T 23-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VMUT_0254 115ec09c0164ec723f10fd5f96d09146 586 Gene3D G3DSA:3.50.50.60 8 409 2.2E-145 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0254 115ec09c0164ec723f10fd5f96d09146 586 Gene3D G3DSA:1.20.58.100 431 548 6.4E-35 T 23-10-2018 VMUT_1686 feff9e23045a5dc4224d107c9601ae4e 164 Pfam PF01230 HIT domain 34 127 7.8E-11 T 23-10-2018 IPR001310 Histidine triad (HIT) protein VMUT_1686 feff9e23045a5dc4224d107c9601ae4e 164 SUPERFAMILY SSF54197 1 131 1.5E-31 T 23-10-2018 IPR036265 HIT-like superfamily VMUT_1686 feff9e23045a5dc4224d107c9601ae4e 164 Gene3D G3DSA:3.30.428.10 1 160 3.5E-36 T 23-10-2018 IPR036265 HIT-like superfamily VMUT_1556 a499965b73c5c857cb2fe5bfdbf1e55c 188 SMART SM00852 32 182 1.3E-27 T 23-10-2018 IPR001453 MoaB/Mog domain VMUT_1556 a499965b73c5c857cb2fe5bfdbf1e55c 188 SUPERFAMILY SSF53218 27 186 4.84E-39 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily VMUT_1556 a499965b73c5c857cb2fe5bfdbf1e55c 188 PIRSF PIRSF006443 16 188 9.8E-58 T 23-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 VMUT_1556 a499965b73c5c857cb2fe5bfdbf1e55c 188 Pfam PF00994 Probable molybdopterin binding domain 33 181 8.2E-33 T 23-10-2018 IPR001453 MoaB/Mog domain VMUT_1556 a499965b73c5c857cb2fe5bfdbf1e55c 188 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 31 177 4.8E-34 T 23-10-2018 IPR001453 MoaB/Mog domain VMUT_1556 a499965b73c5c857cb2fe5bfdbf1e55c 188 Gene3D G3DSA:3.40.980.10 25 188 3.8E-44 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily VMUT_1556 a499965b73c5c857cb2fe5bfdbf1e55c 188 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 97 110 - T 23-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 VMUT_0979 4a102eba62d99607e95d22b80dda66d5 369 SUPERFAMILY SSF101821 72 181 1.68E-30 T 23-10-2018 VMUT_0979 4a102eba62d99607e95d22b80dda66d5 369 Gene3D G3DSA:3.40.630.10 9 343 3.1E-130 T 23-10-2018 VMUT_0979 4a102eba62d99607e95d22b80dda66d5 369 Pfam PF05343 M42 glutamyl aminopeptidase 47 343 2.6E-102 T 23-10-2018 IPR008007 Peptidase M42 VMUT_0979 4a102eba62d99607e95d22b80dda66d5 369 Gene3D G3DSA:2.40.30.40 71 164 3.1E-130 T 23-10-2018 IPR023367 Peptidase M42, domain 2 VMUT_0979 4a102eba62d99607e95d22b80dda66d5 369 SUPERFAMILY SSF53187 4 353 1.72E-63 T 23-10-2018 VMUT_0979 4a102eba62d99607e95d22b80dda66d5 369 PIRSF PIRSF001123 3 362 9.2E-120 T 23-10-2018 IPR008007 Peptidase M42 VMUT_1236 cb05d1579253b7ecfe7dcbfab33e0b10 99 SUPERFAMILY SSF81301 2 86 1.64E-14 T 23-10-2018 VMUT_1236 cb05d1579253b7ecfe7dcbfab33e0b10 99 Pfam PF01909 Nucleotidyltransferase domain 6 41 1.7E-9 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 VMUT_1236 cb05d1579253b7ecfe7dcbfab33e0b10 99 Gene3D G3DSA:3.30.460.10 1 89 1.9E-12 T 23-10-2018 VMUT_1672 7f23de2c807107e241e6f68741c95c14 139 Hamap MF_01490 Holliday junction resolvase Hjc [hjc]. 4 134 37.159 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal VMUT_1672 7f23de2c807107e241e6f68741c95c14 139 Gene3D G3DSA:3.40.1350.10 1 138 1.5E-37 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 VMUT_1672 7f23de2c807107e241e6f68741c95c14 139 Pfam PF01870 Archaeal holliday junction resolvase (hjc) 11 104 1.9E-27 T 23-10-2018 IPR002732 Holliday junction resolvase Hjc VMUT_1672 7f23de2c807107e241e6f68741c95c14 139 ProDom PD015874 RESOLVASE HOLLIDAY JUNCTION ARCHAEAL HOLLIDAY-JUNCTION TYPE MJ0497 ORF-C21_024 PF1503 NEQ424 12 134 1.0E-27 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal VMUT_1672 7f23de2c807107e241e6f68741c95c14 139 SUPERFAMILY SSF52980 8 109 1.29E-22 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 VMUT_2192 fbf8f9c18743cc7792feaac534a605fb 287 Gene3D G3DSA:1.10.3720.10 74 280 1.7E-19 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_2192 fbf8f9c18743cc7792feaac534a605fb 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 280 3.9E-26 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VMUT_2192 fbf8f9c18743cc7792feaac534a605fb 287 SUPERFAMILY SSF161098 87 265 7.19E-23 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_1322 30d28a28f1a4572c6961d33405fc7ebf 421 Gene3D G3DSA:1.10.287.660 144 256 4.7E-36 T 23-10-2018 IPR029012 Helix hairpin bin domain superfamily VMUT_1322 30d28a28f1a4572c6961d33405fc7ebf 421 Gene3D G3DSA:3.30.420.220 1 138 1.7E-32 T 23-10-2018 VMUT_1322 30d28a28f1a4572c6961d33405fc7ebf 421 Gene3D G3DSA:1.10.246.90 257 380 1.3E-43 T 23-10-2018 VMUT_1322 30d28a28f1a4572c6961d33405fc7ebf 421 Gene3D G3DSA:1.10.150.460 174 225 4.7E-36 T 23-10-2018 VMUT_1322 30d28a28f1a4572c6961d33405fc7ebf 421 SUPERFAMILY SSF89124 138 377 4.84E-74 T 23-10-2018 IPR036070 Nop domain superfamily VMUT_1322 30d28a28f1a4572c6961d33405fc7ebf 421 Pfam PF01798 snoRNA binding domain, fibrillarin 151 376 3.5E-64 T 23-10-2018 IPR002687 Nop domain VMUT_1322 30d28a28f1a4572c6961d33405fc7ebf 421 SMART SM00931 143 195 2.9E-24 T 23-10-2018 IPR012976 NOSIC VMUT_0174 d84363b38f67b688be1f838956389a45 279 PIRSF PIRSF006593 4 278 3.7E-34 T 23-10-2018 IPR014444 Uncharacterised conserved protein UCP006593 VMUT_0174 d84363b38f67b688be1f838956389a45 279 Pfam PF01937 Protein of unknown function DUF89 56 267 1.6E-19 T 23-10-2018 IPR002791 Domain of unknown function DUF89 VMUT_0174 d84363b38f67b688be1f838956389a45 279 Gene3D G3DSA:3.40.50.10880 131 277 1.3E-26 T 23-10-2018 VMUT_0174 d84363b38f67b688be1f838956389a45 279 SUPERFAMILY SSF111321 7 276 4.45E-49 T 23-10-2018 IPR036075 AF1104-like superfamily VMUT_0728 e51758bc28f3fd23d2fa802401bccf11 323 Pfam PF01435 Peptidase family M48 83 317 2.0E-33 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 VMUT_0728 e51758bc28f3fd23d2fa802401bccf11 323 Hamap MF_00188 Protease HtpX [htpX]. 7 318 27.728 T 23-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 VMUT_0728 e51758bc28f3fd23d2fa802401bccf11 323 Gene3D G3DSA:3.30.2010.10 74 164 5.5E-18 T 23-10-2018 VMUT_0115 aa88b63361dcfa12d76c964beba0ea08 429 Pfam PF01266 FAD dependent oxidoreductase 4 355 9.6E-45 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VMUT_0115 aa88b63361dcfa12d76c964beba0ea08 429 SUPERFAMILY SSF51905 3 358 2.41E-38 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0115 aa88b63361dcfa12d76c964beba0ea08 429 Gene3D G3DSA:3.50.50.60 4 354 1.6E-66 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0115 aa88b63361dcfa12d76c964beba0ea08 429 SUPERFAMILY SSF54373 220 309 4.19E-8 T 23-10-2018 VMUT_0115 aa88b63361dcfa12d76c964beba0ea08 429 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 16 26 4.6E-15 T 23-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 VMUT_0115 aa88b63361dcfa12d76c964beba0ea08 429 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 32 44 4.6E-15 T 23-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 VMUT_0115 aa88b63361dcfa12d76c964beba0ea08 429 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 335 347 4.6E-15 T 23-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 VMUT_0115 aa88b63361dcfa12d76c964beba0ea08 429 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 3 15 4.6E-15 T 23-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 VMUT_0115 aa88b63361dcfa12d76c964beba0ea08 429 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 303 309 4.6E-15 T 23-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 VMUT_0115 aa88b63361dcfa12d76c964beba0ea08 429 Gene3D G3DSA:3.30.9.10 80 310 1.6E-66 T 23-10-2018 VMUT_2327 3fb3f02765356e33057906163679446c 386 Gene3D G3DSA:1.10.540.10 3 124 3.9E-27 T 23-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VMUT_2327 3fb3f02765356e33057906163679446c 386 SUPERFAMILY SSF56645 7 243 1.28E-64 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VMUT_2327 3fb3f02765356e33057906163679446c 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 381 1.1E-39 T 23-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VMUT_2327 3fb3f02765356e33057906163679446c 386 SUPERFAMILY SSF47203 231 384 4.34E-43 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VMUT_2327 3fb3f02765356e33057906163679446c 386 PIRSF PIRSF016578 2 383 6.1E-23 T 23-10-2018 VMUT_2327 3fb3f02765356e33057906163679446c 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 122 7.9E-22 T 23-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VMUT_2327 3fb3f02765356e33057906163679446c 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 220 6.2E-22 T 23-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VMUT_2327 3fb3f02765356e33057906163679446c 386 Gene3D G3DSA:2.40.110.10 125 237 4.8E-34 T 23-10-2018 VMUT_2327 3fb3f02765356e33057906163679446c 386 Gene3D G3DSA:1.20.140.10 238 384 8.1E-40 T 23-10-2018 VMUT_0572 8e5cf464e7b55dbcbe2c9cc8fee8c7a9 124 SUPERFAMILY SSF46785 7 112 1.95E-29 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0572 8e5cf464e7b55dbcbe2c9cc8fee8c7a9 124 Gene3D G3DSA:1.10.10.10 2 124 4.2E-36 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_0572 8e5cf464e7b55dbcbe2c9cc8fee8c7a9 124 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 28 88 3.3E-14 T 23-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VMUT_0067 1162a367323e11d6a31f97b779b9a502 435 Pfam PF00534 Glycosyl transferases group 1 247 395 2.7E-20 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 VMUT_0067 1162a367323e11d6a31f97b779b9a502 435 SUPERFAMILY SSF53756 19 430 2.75E-36 T 23-10-2018 VMUT_0067 1162a367323e11d6a31f97b779b9a502 435 Gene3D G3DSA:3.40.50.2000 6 196 4.8E-6 T 23-10-2018 VMUT_0067 1162a367323e11d6a31f97b779b9a502 435 Gene3D G3DSA:3.40.50.2000 237 399 1.7E-26 T 23-10-2018 VMUT_0032 abfc5e8a81ecb5e88a4fecf88a75765a 277 Gene3D G3DSA:3.40.50.970 73 222 7.4E-29 T 23-10-2018 VMUT_0032 abfc5e8a81ecb5e88a4fecf88a75765a 277 SUPERFAMILY SSF52518 5 265 8.84E-65 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold VMUT_0032 abfc5e8a81ecb5e88a4fecf88a75765a 277 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 74 206 4.0E-31 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 VMUT_1187 6a1ba026db0a0f99efb4a4e589100734 143 Pfam PF01934 Protein of unknown function DUF86 13 129 1.3E-18 T 23-10-2018 IPR008201 Protein of unknown function DUF86 VMUT_1187 6a1ba026db0a0f99efb4a4e589100734 143 Gene3D G3DSA:1.20.120.580 8 138 1.2E-12 T 23-10-2018 IPR037038 Bsu32300-like superfamily VMUT_1616 9017e0cd3e2e51d81321e6a22898ac51 257 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 12 242 33.539 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 VMUT_1616 9017e0cd3e2e51d81321e6a22898ac51 257 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 17 240 2.5E-71 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 VMUT_1616 9017e0cd3e2e51d81321e6a22898ac51 257 SUPERFAMILY SSF51395 17 240 1.43E-43 T 23-10-2018 VMUT_1616 9017e0cd3e2e51d81321e6a22898ac51 257 Pfam PF01884 PcrB family 18 243 8.7E-57 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 VMUT_1616 9017e0cd3e2e51d81321e6a22898ac51 257 Gene3D G3DSA:3.20.20.390 1 247 6.4E-84 T 23-10-2018 IPR038597 GGGP/HepGP synthase superfamily VMUT_1616 9017e0cd3e2e51d81321e6a22898ac51 257 TIGRFAM TIGR01769 GGGP: phosphoglycerol geranylgeranyltransferase 18 226 4.0E-82 T 23-10-2018 IPR010946 Geranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005737|GO:0006650|GO:0047294 KEGG: 00564+2.5.1.41|MetaCyc: PWY-6349 VMUT_2070 1f99b79e9407bc3d29cad5b7be194cdd 301 Gene3D G3DSA:3.40.1190.20 4 296 7.3E-49 T 23-10-2018 IPR029056 Ribokinase-like VMUT_2070 1f99b79e9407bc3d29cad5b7be194cdd 301 SUPERFAMILY SSF53613 6 289 6.86E-52 T 23-10-2018 IPR029056 Ribokinase-like VMUT_2070 1f99b79e9407bc3d29cad5b7be194cdd 301 Pfam PF00294 pfkB family carbohydrate kinase 8 289 1.3E-32 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB VMUT_0845 7c2e1107129830463fcbd2a062f9b183 393 SUPERFAMILY SSF51905 1 146 2.99E-19 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0845 7c2e1107129830463fcbd2a062f9b183 393 SUPERFAMILY SSF51905 122 253 6.71E-26 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0845 7c2e1107129830463fcbd2a062f9b183 393 Gene3D G3DSA:3.50.50.60 4 321 9.6E-81 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0845 7c2e1107129830463fcbd2a062f9b183 393 Gene3D G3DSA:3.50.50.60 118 262 9.6E-81 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0845 7c2e1107129830463fcbd2a062f9b183 393 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 143 7.0E-12 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VMUT_0226 48dd17bf373e5d2756c0cac71ef65363 312 Gene3D G3DSA:1.20.1250.20 183 311 2.8E-9 T 23-10-2018 VMUT_0226 48dd17bf373e5d2756c0cac71ef65363 312 SUPERFAMILY SSF103473 11 172 1.96E-9 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_0226 48dd17bf373e5d2756c0cac71ef65363 312 SUPERFAMILY SSF103473 194 296 4.05E-10 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_0226 48dd17bf373e5d2756c0cac71ef65363 312 Gene3D G3DSA:1.20.1250.20 9 182 2.3E-7 T 23-10-2018 VMUT_0404 c6eb2727ef15447aa7661de85d5420f4 810 SUPERFAMILY SSF81665 254 773 5.75E-17 T 23-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 VMUT_0404 c6eb2727ef15447aa7661de85d5420f4 810 Gene3D G3DSA:3.40.1110.10 516 633 5.7E-89 T 23-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 VMUT_0404 c6eb2727ef15447aa7661de85d5420f4 810 Pfam PF00702 haloacid dehalogenase-like hydrolase 502 715 2.1E-43 T 23-10-2018 VMUT_0404 c6eb2727ef15447aa7661de85d5420f4 810 Pfam PF00403 Heavy-metal-associated domain 25 86 4.5E-15 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 VMUT_0404 c6eb2727ef15447aa7661de85d5420f4 810 Gene3D G3DSA:3.40.50.1000 486 752 5.7E-89 T 23-10-2018 IPR023214 HAD superfamily VMUT_0404 c6eb2727ef15447aa7661de85d5420f4 810 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 243 807 3.1E-176 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 VMUT_0404 c6eb2727ef15447aa7661de85d5420f4 810 ProSitePatterns PS01047 Heavy-metal-associated domain. 28 57 - T 23-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 VMUT_0404 c6eb2727ef15447aa7661de85d5420f4 810 Gene3D G3DSA:3.30.70.100 19 88 5.3E-18 T 23-10-2018 VMUT_0404 c6eb2727ef15447aa7661de85d5420f4 810 SUPERFAMILY SSF55008 18 88 1.57E-18 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 VMUT_0404 c6eb2727ef15447aa7661de85d5420f4 810 SUPERFAMILY SSF56784 503 805 1.7E-55 T 23-10-2018 IPR036412 HAD-like superfamily VMUT_0404 c6eb2727ef15447aa7661de85d5420f4 810 SUPERFAMILY SSF81653 308 404 1.05E-23 T 23-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 VMUT_0404 c6eb2727ef15447aa7661de85d5420f4 810 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 505 519 3.5E-27 T 23-10-2018 VMUT_0404 c6eb2727ef15447aa7661de85d5420f4 810 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 724 736 3.5E-27 T 23-10-2018 VMUT_0404 c6eb2727ef15447aa7661de85d5420f4 810 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 648 658 3.5E-27 T 23-10-2018 VMUT_0404 c6eb2727ef15447aa7661de85d5420f4 810 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 701 720 3.5E-27 T 23-10-2018 VMUT_0404 c6eb2727ef15447aa7661de85d5420f4 810 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 355 369 3.5E-27 T 23-10-2018 VMUT_0404 c6eb2727ef15447aa7661de85d5420f4 810 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 626 637 3.5E-27 T 23-10-2018 VMUT_0404 c6eb2727ef15447aa7661de85d5420f4 810 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 279 779 1.0E-89 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VMUT_0404 c6eb2727ef15447aa7661de85d5420f4 810 Gene3D G3DSA:2.70.150.20 298 410 2.5E-30 T 23-10-2018 VMUT_0404 c6eb2727ef15447aa7661de85d5420f4 810 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 507 513 - T 23-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 VMUT_0404 c6eb2727ef15447aa7661de85d5420f4 810 Pfam PF00122 E1-E2 ATPase 306 485 9.7E-48 T 23-10-2018 VMUT_0404 c6eb2727ef15447aa7661de85d5420f4 810 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 225 808 1.1E-161 T 23-10-2018 VMUT_1771 dd8178e37fe7dd6be63f6d5fc55cc906 187 SUPERFAMILY SSF52972 1 185 1.31E-52 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like VMUT_1771 dd8178e37fe7dd6be63f6d5fc55cc906 187 Gene3D G3DSA:3.90.950.10 1 186 8.4E-59 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like VMUT_1771 dd8178e37fe7dd6be63f6d5fc55cc906 187 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 183 1.4E-51 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 VMUT_1771 dd8178e37fe7dd6be63f6d5fc55cc906 187 Pfam PF01725 Ham1 family 3 181 7.2E-43 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 VMUT_0288 a38e12b9f1da849c73c27c6c04356868 290 SUPERFAMILY SSF103481 190 284 1.57E-11 T 23-10-2018 VMUT_0288 a38e12b9f1da849c73c27c6c04356868 290 SUPERFAMILY SSF103481 36 138 5.62E-11 T 23-10-2018 VMUT_0288 a38e12b9f1da849c73c27c6c04356868 290 Pfam PF00892 EamA-like transporter family 7 135 1.2E-14 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VMUT_0288 a38e12b9f1da849c73c27c6c04356868 290 Pfam PF00892 EamA-like transporter family 147 281 4.9E-11 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VMUT_0463 feffadda0306a1d1f8bbaa20435c4350 285 Pfam PF08823 Putative peptidoglycan binding domain 199 272 7.3E-24 T 23-10-2018 IPR014927 Putative peptidoglycan binding VMUT_0463 feffadda0306a1d1f8bbaa20435c4350 285 Pfam PF06267 Family of unknown function (DUF1028) 7 189 2.4E-67 T 23-10-2018 IPR010430 Protein of unknown function DUF1028 VMUT_0463 feffadda0306a1d1f8bbaa20435c4350 285 SUPERFAMILY SSF56235 8 201 1.31E-62 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VMUT_0463 feffadda0306a1d1f8bbaa20435c4350 285 Gene3D G3DSA:3.60.20.10 1 205 1.9E-69 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VMUT_2345 4af0d302cd6d919ace2e8e11bdd5ce65 149 Pfam PF02635 DsrE/DsrF-like family 38 146 4.2E-7 T 23-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein VMUT_2345 4af0d302cd6d919ace2e8e11bdd5ce65 149 SUPERFAMILY SSF75169 15 148 1.71E-15 T 23-10-2018 IPR027396 DsrEFH-like VMUT_2345 4af0d302cd6d919ace2e8e11bdd5ce65 149 Gene3D G3DSA:3.40.1260.10 9 149 1.3E-28 T 23-10-2018 IPR027396 DsrEFH-like VMUT_1839 d7a43ccab3d48aca1db345b6fa741144 339 Pfam PF07885 Ion channel 30 107 8.2E-16 T 23-10-2018 IPR013099 Potassium channel domain VMUT_1839 d7a43ccab3d48aca1db345b6fa741144 339 SUPERFAMILY SSF51735 124 272 5.61E-14 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1839 d7a43ccab3d48aca1db345b6fa741144 339 Gene3D G3DSA:3.40.50.720 115 251 6.3E-21 T 23-10-2018 VMUT_1839 d7a43ccab3d48aca1db345b6fa741144 339 PRINTS PR00169 Potassium channel signature 20 43 7.8E-6 T 23-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 VMUT_1839 d7a43ccab3d48aca1db345b6fa741144 339 PRINTS PR00169 Potassium channel signature 51 73 7.8E-6 T 23-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 VMUT_1839 d7a43ccab3d48aca1db345b6fa741144 339 PRINTS PR00169 Potassium channel signature 80 106 7.8E-6 T 23-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 VMUT_1839 d7a43ccab3d48aca1db345b6fa741144 339 SUPERFAMILY SSF116726 301 338 1.23E-5 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 VMUT_1839 d7a43ccab3d48aca1db345b6fa741144 339 SUPERFAMILY SSF81324 10 138 1.03E-28 T 23-10-2018 VMUT_1839 d7a43ccab3d48aca1db345b6fa741144 339 PRINTS PR01333 Two pore domain K+ channel signature 248 257 1.4E-5 T 23-10-2018 IPR003280 Two pore domain potassium channel GO:0005267|GO:0016020|GO:0071805 Reactome: R-HSA-5576886 VMUT_1839 d7a43ccab3d48aca1db345b6fa741144 339 PRINTS PR01333 Two pore domain K+ channel signature 63 91 1.4E-5 T 23-10-2018 IPR003280 Two pore domain potassium channel GO:0005267|GO:0016020|GO:0071805 Reactome: R-HSA-5576886 VMUT_1839 d7a43ccab3d48aca1db345b6fa741144 339 Pfam PF02254 TrkA-N domain 170 251 5.7E-10 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 VMUT_1839 d7a43ccab3d48aca1db345b6fa741144 339 Gene3D G3DSA:1.10.287.70 3 110 9.5E-27 T 23-10-2018 VMUT_1447 59dca2e72391f9ee4f3c8c6b6cc212be 184 PIRSF PIRSF005285 5 184 1.3E-54 T 23-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 VMUT_1447 59dca2e72391f9ee4f3c8c6b6cc212be 184 Pfam PF02778 tRNA intron endonuclease, N-terminal domain 3 80 9.3E-19 T 23-10-2018 IPR006678 tRNA intron endonuclease, N-terminal GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 VMUT_1447 59dca2e72391f9ee4f3c8c6b6cc212be 184 Gene3D G3DSA:3.40.1170.20 2 89 1.0E-27 T 23-10-2018 VMUT_1447 59dca2e72391f9ee4f3c8c6b6cc212be 184 SUPERFAMILY SSF53032 90 181 6.28E-22 T 23-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 VMUT_1447 59dca2e72391f9ee4f3c8c6b6cc212be 184 SUPERFAMILY SSF55267 3 85 1.16E-15 T 23-10-2018 IPR036740 tRNA intron endonuclease, N-terminal domain superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803 VMUT_1447 59dca2e72391f9ee4f3c8c6b6cc212be 184 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 91 168 1.2E-23 T 23-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 VMUT_1447 59dca2e72391f9ee4f3c8c6b6cc212be 184 Gene3D G3DSA:3.40.1350.10 90 184 1.0E-27 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 VMUT_1447 59dca2e72391f9ee4f3c8c6b6cc212be 184 TIGRFAM TIGR00324 endA: tRNA-intron lyase 43 181 1.8E-30 T 23-10-2018 IPR006676 tRNA-splicing endonuclease GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 VMUT_0658 2241949e9b924524a246d5ae49cda5e5 221 SUPERFAMILY SSF56524 25 206 4.97E-55 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 VMUT_0658 2241949e9b924524a246d5ae49cda5e5 221 Gene3D G3DSA:3.90.420.10 35 220 9.0E-45 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 VMUT_0658 2241949e9b924524a246d5ae49cda5e5 221 Pfam PF00174 Oxidoreductase molybdopterin binding domain 48 188 1.3E-34 T 23-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 VMUT_0960 c01ec1a947d5b46ec9771b7203cdc911 411 Hamap MF_00136 S-adenosylmethionine synthase [mat]. 4 411 51.208 T 23-10-2018 IPR002795 S-adenosylmethionine synthetase, archaea GO:0004478|GO:0005524|GO:0006730 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 VMUT_0960 c01ec1a947d5b46ec9771b7203cdc911 411 Gene3D G3DSA:3.30.300.10 29 161 1.2E-157 T 23-10-2018 VMUT_0960 c01ec1a947d5b46ec9771b7203cdc911 411 ProDom PD011777 SYNTHETASE TRANSFERASE METHIONINE ADENOSYLTRANSFERASE S-ADENOSYLMETHIONINE NUCLEOTIDE-BINDING METABOLISM ATP-BINDING MAGNESIUM ONE-CARBON 23 402 7.0E-150 T 23-10-2018 VMUT_0960 c01ec1a947d5b46ec9771b7203cdc911 411 Gene3D G3DSA:3.30.300.340 17 291 1.2E-157 T 23-10-2018 VMUT_0960 c01ec1a947d5b46ec9771b7203cdc911 411 Pfam PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) 5 406 1.2E-173 T 23-10-2018 IPR027790 S-adenosylmethionine synthase KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 VMUT_0960 c01ec1a947d5b46ec9771b7203cdc911 411 Gene3D G3DSA:3.30.300.280 15 404 1.2E-157 T 23-10-2018 VMUT_1160 1fc1eea52a4c5356143819e79811af39 311 SUPERFAMILY SSF141130 7 306 1.27E-83 T 23-10-2018 VMUT_1160 1fc1eea52a4c5356143819e79811af39 311 Gene3D G3DSA:3.10.28.20 233 308 1.4E-10 T 23-10-2018 VMUT_1160 1fc1eea52a4c5356143819e79811af39 311 Gene3D G3DSA:2.60.120.580 3 106 1.3E-20 T 23-10-2018 VMUT_1160 1fc1eea52a4c5356143819e79811af39 311 Gene3D G3DSA:2.60.120.580 123 219 4.2E-33 T 23-10-2018 VMUT_1160 1fc1eea52a4c5356143819e79811af39 311 Pfam PF03069 Acetamidase/Formamidase family 8 148 5.0E-22 T 23-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 VMUT_1160 1fc1eea52a4c5356143819e79811af39 311 Pfam PF03069 Acetamidase/Formamidase family 153 307 3.2E-31 T 23-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 VMUT_0363 2e3bef40cb39589d183b5b4b4edd7726 246 Gene3D G3DSA:3.60.10.10 1 244 2.2E-78 T 23-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily VMUT_0363 2e3bef40cb39589d183b5b4b4edd7726 246 SUPERFAMILY SSF56219 1 244 7.59E-64 T 23-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily VMUT_0363 2e3bef40cb39589d183b5b4b4edd7726 246 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 244 8.5E-67 T 23-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 VMUT_0363 2e3bef40cb39589d183b5b4b4edd7726 246 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 243 4.5E-63 T 23-10-2018 VMUT_0363 2e3bef40cb39589d183b5b4b4edd7726 246 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 237 6.2E-12 T 23-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase VMUT_1552 d204d48ed23f1235c30a0bf0cf3f401f 148 Gene3D G3DSA:3.30.530.20 3 148 1.2E-34 T 23-10-2018 IPR023393 START-like domain superfamily VMUT_1552 d204d48ed23f1235c30a0bf0cf3f401f 148 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 8 148 8.3E-34 T 23-10-2018 IPR010419 Carbon monoxide dehydrogenase subunit G VMUT_1552 d204d48ed23f1235c30a0bf0cf3f401f 148 SUPERFAMILY SSF55961 6 147 2.65E-32 T 23-10-2018 VMUT_1440 73daa185e570d1b51662f228ec4e06d0 445 SUPERFAMILY SSF51556 62 355 9.91E-47 T 23-10-2018 IPR032466 Metal-dependent hydrolase VMUT_1440 73daa185e570d1b51662f228ec4e06d0 445 Gene3D G3DSA:2.30.40.10 7 425 5.0E-90 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VMUT_1440 73daa185e570d1b51662f228ec4e06d0 445 Pfam PF01979 Amidohydrolase family 59 406 5.7E-30 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VMUT_1440 73daa185e570d1b51662f228ec4e06d0 445 SUPERFAMILY SSF51338 5 429 1.07E-25 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VMUT_1440 73daa185e570d1b51662f228ec4e06d0 445 Gene3D G3DSA:3.20.20.140 63 354 5.0E-90 T 23-10-2018 VMUT_1662 0a52d89d40b7a96f30f3a29a1e5cb2cc 605 Gene3D G3DSA:3.50.50.60 125 365 2.3E-20 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_1662 0a52d89d40b7a96f30f3a29a1e5cb2cc 605 SUPERFAMILY SSF51905 119 420 1.17E-27 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_1662 0a52d89d40b7a96f30f3a29a1e5cb2cc 605 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 125 358 3.1E-14 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VMUT_1662 0a52d89d40b7a96f30f3a29a1e5cb2cc 605 Gene3D G3DSA:1.10.10.1100 486 583 1.1E-6 T 23-10-2018 VMUT_1662 0a52d89d40b7a96f30f3a29a1e5cb2cc 605 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 260 284 9.5E-7 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VMUT_1662 0a52d89d40b7a96f30f3a29a1e5cb2cc 605 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 175 185 9.5E-7 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VMUT_1662 0a52d89d40b7a96f30f3a29a1e5cb2cc 605 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 125 147 9.5E-7 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VMUT_1662 0a52d89d40b7a96f30f3a29a1e5cb2cc 605 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 222 230 9.5E-7 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VMUT_1662 0a52d89d40b7a96f30f3a29a1e5cb2cc 605 Gene3D G3DSA:3.50.50.60 233 359 2.3E-20 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_1289 0aa441aad95fb9fc8db6d818f21e1f91 261 Gene3D G3DSA:1.10.150.400 21 112 4.2E-35 T 23-10-2018 VMUT_1289 0aa441aad95fb9fc8db6d818f21e1f91 261 Pfam PF13419 Haloacid dehalogenase-like hydrolase 83 211 1.5E-13 T 23-10-2018 VMUT_1289 0aa441aad95fb9fc8db6d818f21e1f91 261 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 128 141 6.8E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VMUT_1289 0aa441aad95fb9fc8db6d818f21e1f91 261 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 8 19 6.8E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VMUT_1289 0aa441aad95fb9fc8db6d818f21e1f91 261 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 162 178 6.8E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VMUT_1289 0aa441aad95fb9fc8db6d818f21e1f91 261 Gene3D G3DSA:3.40.50.1000 9 224 4.2E-35 T 23-10-2018 IPR023214 HAD superfamily VMUT_1289 0aa441aad95fb9fc8db6d818f21e1f91 261 SUPERFAMILY SSF56784 9 225 2.48E-28 T 23-10-2018 IPR036412 HAD-like superfamily VMUT_0040 b42e3502aec8c1703460ead1ffa29d6b 259 Gene3D G3DSA:3.90.550.10 3 239 1.3E-21 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0040 b42e3502aec8c1703460ead1ffa29d6b 259 Pfam PF00535 Glycosyl transferase family 2 6 106 1.1E-13 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VMUT_0040 b42e3502aec8c1703460ead1ffa29d6b 259 SUPERFAMILY SSF53448 7 232 2.16E-27 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1836 7813526478f6b9cb1f3f88a610eb1cfd 442 PIRSF PIRSF006060 3 441 3.3E-59 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_1836 7813526478f6b9cb1f3f88a610eb1cfd 442 Gene3D G3DSA:1.20.1740.10 7 442 2.1E-60 T 23-10-2018 VMUT_1836 7813526478f6b9cb1f3f88a610eb1cfd 442 Pfam PF13520 Amino acid permease 12 415 3.6E-42 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_1330 be7f8519e0ced8ee46275ef98fe6cc15 121 Gene3D G3DSA:1.20.1300.10 2 119 4.5E-6 T 23-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VMUT_1330 be7f8519e0ced8ee46275ef98fe6cc15 121 SUPERFAMILY SSF81343 14 113 1.79E-8 T 23-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VMUT_1227 d00468373d6001e15b570a0e68f62f5e 385 SUPERFAMILY SSF53901 247 369 7.37E-16 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_1227 d00468373d6001e15b570a0e68f62f5e 385 PIRSF PIRSF000429 1 367 1.8E-14 T 23-10-2018 IPR002155 Thiolase GO:0016747 VMUT_1227 d00468373d6001e15b570a0e68f62f5e 385 SUPERFAMILY SSF53901 2 227 2.12E-18 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_1227 d00468373d6001e15b570a0e68f62f5e 385 Gene3D G3DSA:3.40.47.10 1 385 2.1E-76 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_2286 a02815ebd6caae89747b035ee2dde4f1 650 SUPERFAMILY SSF56281 192 649 2.36E-123 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_2286 a02815ebd6caae89747b035ee2dde4f1 650 SMART SM00849 204 414 1.1E-20 T 23-10-2018 IPR001279 Metallo-beta-lactamase VMUT_2286 a02815ebd6caae89747b035ee2dde4f1 650 Pfam PF17214 KH domain 12 76 1.4E-23 T 23-10-2018 IPR033769 KH domain, archaeal VMUT_2286 a02815ebd6caae89747b035ee2dde4f1 650 Pfam PF10996 Beta-Casp domain 430 560 6.6E-21 T 23-10-2018 IPR022712 Beta-Casp domain VMUT_2286 a02815ebd6caae89747b035ee2dde4f1 650 Gene3D G3DSA:3.30.300.230 17 182 3.8E-46 T 23-10-2018 VMUT_2286 a02815ebd6caae89747b035ee2dde4f1 650 Pfam PF00753 Metallo-beta-lactamase superfamily 204 401 7.5E-15 T 23-10-2018 IPR001279 Metallo-beta-lactamase VMUT_2286 a02815ebd6caae89747b035ee2dde4f1 650 SMART SM01027 430 560 1.4E-41 T 23-10-2018 IPR022712 Beta-Casp domain VMUT_2286 a02815ebd6caae89747b035ee2dde4f1 650 Gene3D G3DSA:3.40.50.10890 398 590 2.2E-140 T 23-10-2018 VMUT_2286 a02815ebd6caae89747b035ee2dde4f1 650 Gene3D G3DSA:3.30.300.20 72 143 3.8E-46 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta VMUT_2286 a02815ebd6caae89747b035ee2dde4f1 650 Gene3D G3DSA:3.60.15.10 197 627 2.2E-140 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_2286 a02815ebd6caae89747b035ee2dde4f1 650 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 577 630 3.8E-14 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain VMUT_2286 a02815ebd6caae89747b035ee2dde4f1 650 TIGRFAM TIGR03675 arCOG00543: arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein 13 649 7.8E-237 T 23-10-2018 IPR019975 KH-domain/beta-lactamase-domain protein, archaea VMUT_1425 44b753ffcc078ea2edd8adb6399d860f 433 PIRSF PIRSF000505 1 428 1.1E-96 T 23-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 VMUT_1425 44b753ffcc078ea2edd8adb6399d860f 433 Gene3D G3DSA:3.65.10.10 222 432 1.2E-47 T 23-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 VMUT_1425 44b753ffcc078ea2edd8adb6399d860f 433 SUPERFAMILY SSF55205 1 425 4.58E-84 T 23-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 VMUT_1425 44b753ffcc078ea2edd8adb6399d860f 433 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 10 425 25.4 T 23-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 VMUT_1425 44b753ffcc078ea2edd8adb6399d860f 433 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 13 416 1.1E-75 T 23-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 VMUT_1425 44b753ffcc078ea2edd8adb6399d860f 433 Gene3D G3DSA:3.65.10.10 22 221 9.2E-41 T 23-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 VMUT_1425 44b753ffcc078ea2edd8adb6399d860f 433 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 14 424 2.4E-89 T 23-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 VMUT_1356 32f682b20927efdfe601215f050268b3 247 Hamap MF_00995 Chorismate dehydratase [mqnA]. 5 240 19.393 T 23-10-2018 IPR030868 Chorismate dehydratase GO:0009234|GO:0016829 KEGG: 00130+4.2.1.151|MetaCyc: PWY-7371|MetaCyc: PWY-7374 VMUT_1356 32f682b20927efdfe601215f050268b3 247 SUPERFAMILY SSF53850 3 233 2.04E-45 T 23-10-2018 VMUT_1356 32f682b20927efdfe601215f050268b3 247 Gene3D G3DSA:3.40.190.10 33 227 6.6E-28 T 23-10-2018 VMUT_1356 32f682b20927efdfe601215f050268b3 247 Pfam PF02621 Menaquinone biosynthesis 35 229 2.0E-27 T 23-10-2018 IPR003773 Menaquinone biosynthesis enzyme VMUT_1356 32f682b20927efdfe601215f050268b3 247 Gene3D G3DSA:3.40.190.10 71 155 6.6E-28 T 23-10-2018 VMUT_1218 8501d467f02a32bb2ba91bf1e58fa7d0 412 Gene3D G3DSA:3.30.70.3190 306 411 3.6E-9 T 23-10-2018 VMUT_1218 8501d467f02a32bb2ba91bf1e58fa7d0 412 Gene3D G3DSA:3.30.70.2510 197 304 4.0E-5 T 23-10-2018 VMUT_1218 8501d467f02a32bb2ba91bf1e58fa7d0 412 Hamap MF_01893 tRNA pseudouridine synthase Pus10 [pus10]. 7 412 48.571 T 23-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 VMUT_1218 8501d467f02a32bb2ba91bf1e58fa7d0 412 Pfam PF02926 THUMP domain 21 195 1.8E-8 T 23-10-2018 IPR004114 THUMP domain GO:0003723 VMUT_1784 9c85cfc783e18db7fb61dffd12d994e6 456 Pfam PF13662 Toprim domain 172 258 8.7E-7 T 23-10-2018 IPR006171 TOPRIM domain VMUT_1784 9c85cfc783e18db7fb61dffd12d994e6 456 Hamap MF_00007 DNA primase DnaG [dnaG]. 8 444 32.857 T 23-10-2018 IPR020607 DNA primase DnaG, archaea GO:0000178|GO:0003896|GO:0008143 VMUT_1784 9c85cfc783e18db7fb61dffd12d994e6 456 SMART SM00493 172 243 5.0E-9 T 23-10-2018 IPR006171 TOPRIM domain VMUT_1784 9c85cfc783e18db7fb61dffd12d994e6 456 SUPERFAMILY SSF56731 167 296 1.41E-9 T 23-10-2018 VMUT_1784 9c85cfc783e18db7fb61dffd12d994e6 456 Gene3D G3DSA:3.40.1360.10 161 293 2.2E-12 T 23-10-2018 VMUT_0871 48a3cfe7cc16f471d8767b1ed24346d2 631 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 321 560 3.6E-14 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_0871 48a3cfe7cc16f471d8767b1ed24346d2 631 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 2 214 2.2E-39 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_0871 48a3cfe7cc16f471d8767b1ed24346d2 631 SUPERFAMILY SSF56228 2 215 8.76E-40 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily VMUT_0871 48a3cfe7cc16f471d8767b1ed24346d2 631 SMART SM00790 2 215 2.1E-27 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_0871 48a3cfe7cc16f471d8767b1ed24346d2 631 SUPERFAMILY SSF48310 239 616 5.23E-59 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_0871 48a3cfe7cc16f471d8767b1ed24346d2 631 Gene3D G3DSA:3.60.9.10 1 217 9.9E-26 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily VMUT_0871 48a3cfe7cc16f471d8767b1ed24346d2 631 Gene3D G3DSA:1.10.569.10 287 462 2.4E-15 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 VMUT_1232 5a3bcf27293bfb1cf02e6c4bc425a1d1 263 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 9 251 3.2E-90 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 VMUT_1232 5a3bcf27293bfb1cf02e6c4bc425a1d1 263 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 11 257 32.198 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 VMUT_1232 5a3bcf27293bfb1cf02e6c4bc425a1d1 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 30 51 2.2E-37 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 VMUT_1232 5a3bcf27293bfb1cf02e6c4bc425a1d1 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 61 69 2.2E-37 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 VMUT_1232 5a3bcf27293bfb1cf02e6c4bc425a1d1 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 17 24 2.2E-37 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 VMUT_1232 5a3bcf27293bfb1cf02e6c4bc425a1d1 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 160 177 2.2E-37 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 VMUT_1232 5a3bcf27293bfb1cf02e6c4bc425a1d1 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 87 104 2.2E-37 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 VMUT_1232 5a3bcf27293bfb1cf02e6c4bc425a1d1 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 118 132 2.2E-37 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 VMUT_1232 5a3bcf27293bfb1cf02e6c4bc425a1d1 263 SUPERFAMILY SSF53613 5 253 5.3E-60 T 23-10-2018 IPR029056 Ribokinase-like VMUT_1232 5a3bcf27293bfb1cf02e6c4bc425a1d1 263 Gene3D G3DSA:3.40.1190.20 3 260 4.7E-94 T 23-10-2018 IPR029056 Ribokinase-like VMUT_1232 5a3bcf27293bfb1cf02e6c4bc425a1d1 263 PIRSF PIRSF000513 3 261 2.3E-95 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 VMUT_1232 5a3bcf27293bfb1cf02e6c4bc425a1d1 263 Pfam PF02110 Hydroxyethylthiazole kinase family 9 250 9.5E-85 T 23-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 VMUT_1930 787da3e7a2dc63c91232a0c9276bf151 218 PIRSF PIRSF000370 1 218 5.7E-39 T 23-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 VMUT_1930 787da3e7a2dc63c91232a0c9276bf151 218 Pfam PF04055 Radical SAM superfamily 26 117 4.5E-12 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_1930 787da3e7a2dc63c91232a0c9276bf151 218 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 1 218 32.533 T 23-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 VMUT_1930 787da3e7a2dc63c91232a0c9276bf151 218 Gene3D G3DSA:3.20.20.70 1 203 2.4E-34 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_1930 787da3e7a2dc63c91232a0c9276bf151 218 SUPERFAMILY SSF102114 26 136 3.14E-17 T 23-10-2018 VMUT_1930 787da3e7a2dc63c91232a0c9276bf151 218 Pfam PF13394 4Fe-4S single cluster domain 22 125 2.2E-11 T 23-10-2018 VMUT_0193 464703ef02f09140a14293f5f1042947 154 Gene3D G3DSA:2.60.120.630 1 148 2.1E-51 T 23-10-2018 IPR023131 Mth639-like domain superfamily VMUT_0193 464703ef02f09140a14293f5f1042947 154 Pfam PF04027 Domain of unknown function (DUF371) 9 138 3.9E-50 T 23-10-2018 IPR007171 Protein of unknown function DUF371 VMUT_2334 6168acd4817a7aff17cb5d1c88303708 198 Gene3D G3DSA:1.10.10.460 148 193 6.1E-25 T 23-10-2018 IPR023160 Ribonuclease HII, helix-loop-helix cap domain superfamily GO:0004523 VMUT_2334 6168acd4817a7aff17cb5d1c88303708 198 Gene3D G3DSA:3.30.420.10 1 147 5.3E-31 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VMUT_2334 6168acd4817a7aff17cb5d1c88303708 198 SUPERFAMILY SSF53098 1 191 1.11E-40 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily VMUT_2334 6168acd4817a7aff17cb5d1c88303708 198 TIGRFAM TIGR00729 TIGR00729: ribonuclease HII 1 190 5.7E-57 T 23-10-2018 IPR004649 Ribonuclease H2, subunit A GO:0004523|GO:0016070 VMUT_2334 6168acd4817a7aff17cb5d1c88303708 198 Pfam PF01351 Ribonuclease HII 2 185 8.3E-39 T 23-10-2018 IPR024567 Ribonuclease HII/HIII domain VMUT_1774 9474ce19eff209b54abae7b046298b14 980 Pfam PF08494 DEAD/H associated 643 821 5.5E-22 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 VMUT_1774 9474ce19eff209b54abae7b046298b14 980 Gene3D G3DSA:3.40.50.300 18 240 5.4E-49 T 23-10-2018 VMUT_1774 9474ce19eff209b54abae7b046298b14 980 PIRSF PIRSF037307 10 980 0.0 T 23-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 VMUT_1774 9474ce19eff209b54abae7b046298b14 980 Pfam PF00271 Helicase conserved C-terminal domain 278 378 7.2E-18 T 23-10-2018 IPR001650 Helicase, C-terminal VMUT_1774 9474ce19eff209b54abae7b046298b14 980 Gene3D G3DSA:3.40.50.300 270 411 3.9E-26 T 23-10-2018 VMUT_1774 9474ce19eff209b54abae7b046298b14 980 SMART SM00490 295 382 2.3E-14 T 23-10-2018 IPR001650 Helicase, C-terminal VMUT_1774 9474ce19eff209b54abae7b046298b14 980 SUPERFAMILY SSF52540 171 379 7.9E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1774 9474ce19eff209b54abae7b046298b14 980 SUPERFAMILY SSF52540 18 230 2.17E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1774 9474ce19eff209b54abae7b046298b14 980 SMART SM00487 40 244 3.5E-37 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain VMUT_1774 9474ce19eff209b54abae7b046298b14 980 Pfam PF00270 DEAD/DEAH box helicase 45 218 5.6E-31 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 VMUT_2293 adabe69c35a6ae9d7bc5a8691e6080d8 136 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 51 113 1.4E-10 T 23-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal VMUT_2293 adabe69c35a6ae9d7bc5a8691e6080d8 136 SUPERFAMILY SSF50249 10 116 9.25E-24 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold VMUT_2293 adabe69c35a6ae9d7bc5a8691e6080d8 136 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 19 47 3.4E-9 T 23-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal VMUT_2293 adabe69c35a6ae9d7bc5a8691e6080d8 136 Gene3D G3DSA:1.10.12.20 6 48 4.4E-6 T 23-10-2018 VMUT_1213 bed12019526cfe43ae48b2c557d1c1b6 268 Hamap MF_00361 NAD kinase [nadK]. 1 267 23.36 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 VMUT_1213 bed12019526cfe43ae48b2c557d1c1b6 268 Pfam PF01513 ATP-NAD kinase 51 250 1.7E-33 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 VMUT_1213 bed12019526cfe43ae48b2c557d1c1b6 268 SUPERFAMILY SSF111331 10 265 1.7E-50 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily VMUT_1213 bed12019526cfe43ae48b2c557d1c1b6 268 Gene3D G3DSA:3.40.50.10330 50 264 1.5E-54 T 23-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 VMUT_1213 bed12019526cfe43ae48b2c557d1c1b6 268 Gene3D G3DSA:2.60.200.30 118 244 1.5E-54 T 23-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 VMUT_1264 f694bf31e6b24f7c6ad4ffbfa0f8254f 334 Gene3D G3DSA:3.40.50.460 141 265 2.4E-88 T 23-10-2018 VMUT_1264 f694bf31e6b24f7c6ad4ffbfa0f8254f 334 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 137 155 2.8E-61 T 23-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 VMUT_1264 f694bf31e6b24f7c6ad4ffbfa0f8254f 334 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 119 136 2.8E-61 T 23-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 VMUT_1264 f694bf31e6b24f7c6ad4ffbfa0f8254f 334 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 157 173 2.8E-61 T 23-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 VMUT_1264 f694bf31e6b24f7c6ad4ffbfa0f8254f 334 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 2.8E-61 T 23-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 VMUT_1264 f694bf31e6b24f7c6ad4ffbfa0f8254f 334 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 29 42 2.8E-61 T 23-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 VMUT_1264 f694bf31e6b24f7c6ad4ffbfa0f8254f 334 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 210 222 2.8E-61 T 23-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 VMUT_1264 f694bf31e6b24f7c6ad4ffbfa0f8254f 334 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 175 192 2.8E-61 T 23-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 VMUT_1264 f694bf31e6b24f7c6ad4ffbfa0f8254f 334 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 253 275 2.8E-61 T 23-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 VMUT_1264 f694bf31e6b24f7c6ad4ffbfa0f8254f 334 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 91 107 2.8E-61 T 23-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 VMUT_1264 f694bf31e6b24f7c6ad4ffbfa0f8254f 334 SUPERFAMILY SSF53784 1 326 1.96E-103 T 23-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 VMUT_1264 f694bf31e6b24f7c6ad4ffbfa0f8254f 334 Gene3D G3DSA:3.40.50.450 2 299 2.4E-88 T 23-10-2018 VMUT_1264 f694bf31e6b24f7c6ad4ffbfa0f8254f 334 Pfam PF00365 Phosphofructokinase 2 288 1.8E-89 T 23-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 VMUT_1264 f694bf31e6b24f7c6ad4ffbfa0f8254f 334 PIRSF PIRSF000532 1 333 5.9E-107 T 23-10-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 VMUT_0078 f7fdd6c765e9771d04fe7dd58daa6c7b 354 SUPERFAMILY SSF53448 5 292 7.43E-64 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0078 f7fdd6c765e9771d04fe7dd58daa6c7b 354 Gene3D G3DSA:2.160.10.10 242 354 9.7E-6 T 23-10-2018 VMUT_0078 f7fdd6c765e9771d04fe7dd58daa6c7b 354 TIGRFAM TIGR01208 rmlA_long: glucose-1-phosphate thymidylyltransferase 5 349 8.1E-106 T 23-10-2018 IPR005908 Glucose-1-phosphate thymidylyltransferase, long form VMUT_0078 f7fdd6c765e9771d04fe7dd58daa6c7b 354 SUPERFAMILY SSF51161 256 352 1.57E-6 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily VMUT_0078 f7fdd6c765e9771d04fe7dd58daa6c7b 354 Gene3D G3DSA:3.90.550.10 2 241 1.7E-57 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0078 f7fdd6c765e9771d04fe7dd58daa6c7b 354 Pfam PF00483 Nucleotidyl transferase 5 234 9.1E-43 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 VMUT_2151 7717e0c9841504736394d09f4c7339f5 413 Pfam PF04895 Archaeal Nre, C-terminal 300 409 4.5E-37 T 23-10-2018 IPR006979 Archaeal Nre, C-terminal VMUT_2151 7717e0c9841504736394d09f4c7339f5 413 Hamap MF_02096 DNA repair protein. 1 409 35.302 T 23-10-2018 IPR033167 Archaeal Nre GO:0006281 VMUT_2151 7717e0c9841504736394d09f4c7339f5 413 Pfam PF04894 Archaeal Nre, N-terminal 17 287 1.3E-102 T 23-10-2018 IPR006978 Archaeal Nre, N-terminal VMUT_0396 9a449dbb508d41e53425951a5526654f 468 SUPERFAMILY SSF55681 158 440 4.42E-76 T 23-10-2018 VMUT_0396 9a449dbb508d41e53425951a5526654f 468 SUPERFAMILY SSF46589 7 113 1.52E-24 T 23-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 VMUT_0396 9a449dbb508d41e53425951a5526654f 468 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 7 108 1.4E-22 T 23-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 VMUT_0396 9a449dbb508d41e53425951a5526654f 468 Gene3D G3DSA:1.10.287.40 6 105 1.6E-23 T 23-10-2018 VMUT_0396 9a449dbb508d41e53425951a5526654f 468 PRINTS PR00981 Seryl-tRNA synthetase signature 375 391 9.0E-27 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 VMUT_0396 9a449dbb508d41e53425951a5526654f 468 PRINTS PR00981 Seryl-tRNA synthetase signature 340 353 9.0E-27 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 VMUT_0396 9a449dbb508d41e53425951a5526654f 468 PRINTS PR00981 Seryl-tRNA synthetase signature 300 313 9.0E-27 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 VMUT_0396 9a449dbb508d41e53425951a5526654f 468 PRINTS PR00981 Seryl-tRNA synthetase signature 288 300 9.0E-27 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 VMUT_0396 9a449dbb508d41e53425951a5526654f 468 PRINTS PR00981 Seryl-tRNA synthetase signature 357 373 9.0E-27 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 VMUT_0396 9a449dbb508d41e53425951a5526654f 468 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 246 423 1.7E-36 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_0396 9a449dbb508d41e53425951a5526654f 468 TIGRFAM TIGR00414 serS: serine--tRNA ligase 7 440 9.0E-131 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 VMUT_0396 9a449dbb508d41e53425951a5526654f 468 Gene3D G3DSA:3.30.930.10 106 447 4.7E-105 T 23-10-2018 VMUT_0396 9a449dbb508d41e53425951a5526654f 468 PIRSF PIRSF001529 5 445 1.6E-125 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 VMUT_1543 ee5246c0287a514679967219ec0ea752 1038 SUPERFAMILY SSF56059 658 920 1.54E-74 T 23-10-2018 VMUT_1543 ee5246c0287a514679967219ec0ea752 1038 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 658 857 1.0E-28 T 23-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VMUT_1543 ee5246c0287a514679967219ec0ea752 1038 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 125 329 5.4E-59 T 23-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VMUT_1543 ee5246c0287a514679967219ec0ea752 1038 Gene3D G3DSA:1.10.1030.10 405 505 4.4E-12 T 23-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VMUT_1543 ee5246c0287a514679967219ec0ea752 1038 Gene3D G3DSA:3.30.1490.20 671 741 1.7E-82 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VMUT_1543 ee5246c0287a514679967219ec0ea752 1038 SUPERFAMILY SSF52440 542 659 1.12E-29 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily VMUT_1543 ee5246c0287a514679967219ec0ea752 1038 SUPERFAMILY SSF48108 389 535 2.22E-26 T 23-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VMUT_1543 ee5246c0287a514679967219ec0ea752 1038 SUPERFAMILY SSF56059 125 394 1.48E-92 T 23-10-2018 VMUT_1543 ee5246c0287a514679967219ec0ea752 1038 SMART SM01096 416 529 4.9E-24 T 23-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VMUT_1543 ee5246c0287a514679967219ec0ea752 1038 Gene3D G3DSA:3.40.50.20 1 112 6.8E-40 T 23-10-2018 VMUT_1543 ee5246c0287a514679967219ec0ea752 1038 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 164 176 1.4E-55 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VMUT_1543 ee5246c0287a514679967219ec0ea752 1038 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 235 252 1.4E-55 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VMUT_1543 ee5246c0287a514679967219ec0ea752 1038 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 292 321 1.4E-55 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VMUT_1543 ee5246c0287a514679967219ec0ea752 1038 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 373 391 1.4E-55 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VMUT_1543 ee5246c0287a514679967219ec0ea752 1038 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 15 29 1.4E-55 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VMUT_1543 ee5246c0287a514679967219ec0ea752 1038 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 44 54 1.4E-55 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VMUT_1543 ee5246c0287a514679967219ec0ea752 1038 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 200 219 1.4E-55 T 23-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VMUT_1543 ee5246c0287a514679967219ec0ea752 1038 Gene3D G3DSA:3.30.470.20 116 396 2.5E-104 T 23-10-2018 VMUT_1543 ee5246c0287a514679967219ec0ea752 1038 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 427 528 5.9E-21 T 23-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VMUT_1543 ee5246c0287a514679967219ec0ea752 1038 Gene3D G3DSA:3.40.50.20 506 647 3.3E-36 T 23-10-2018 VMUT_1543 ee5246c0287a514679967219ec0ea752 1038 Gene3D G3DSA:3.30.470.20 653 917 1.7E-82 T 23-10-2018 VMUT_1543 ee5246c0287a514679967219ec0ea752 1038 SUPERFAMILY SSF52440 2 121 1.87E-38 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily VMUT_1543 ee5246c0287a514679967219ec0ea752 1038 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 826 833 - T 23-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VMUT_1543 ee5246c0287a514679967219ec0ea752 1038 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 953 0.0 T 23-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VMUT_0896 77f5d0221e645fca370e3a60929ee063 180 PIRSF PIRSF005590 1 179 5.6E-64 T 23-10-2018 IPR001197 Ribosomal protein L10e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0896 77f5d0221e645fca370e3a60929ee063 180 Pfam PF00252 Ribosomal protein L16p/L10e 13 167 1.4E-31 T 23-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 VMUT_0896 77f5d0221e645fca370e3a60929ee063 180 SUPERFAMILY SSF54686 4 170 5.63E-51 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 VMUT_0896 77f5d0221e645fca370e3a60929ee063 180 ProSitePatterns PS01257 Ribosomal protein L10e signature. 108 129 - T 23-10-2018 IPR018255 Ribosomal protein L10e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0896 77f5d0221e645fca370e3a60929ee063 180 Hamap MF_00448 50S ribosomal protein L10e [rpl10e]. 1 176 34.454 T 23-10-2018 IPR022981 Ribosomal protein L10e, archaea VMUT_0896 77f5d0221e645fca370e3a60929ee063 180 Gene3D G3DSA:3.90.1170.10 1 179 1.1E-63 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 VMUT_0056 83ed33873ce9cb9b92e70f3d62593c64 528 PIRSF PIRSF006060 460 528 21.0 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_0056 83ed33873ce9cb9b92e70f3d62593c64 528 PIRSF PIRSF006060 1 468 6.6E-65 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_0056 83ed33873ce9cb9b92e70f3d62593c64 528 Gene3D G3DSA:1.20.1740.10 15 466 1.5E-58 T 23-10-2018 VMUT_0056 83ed33873ce9cb9b92e70f3d62593c64 528 Pfam PF13520 Amino acid permease 20 433 1.1E-32 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_1483 72e8b340497c01885e4db613effa711e 293 TIGRFAM TIGR02619 TIGR02619: putative CRISPR-associated protein, APE2256 family 70 228 2.3E-24 T 23-10-2018 IPR013442 CRISPR-associated protein APE2256 VMUT_1483 72e8b340497c01885e4db613effa711e 293 Pfam PF09651 CRISPR-associated protein (Cas_APE2256) 77 228 3.1E-37 T 23-10-2018 IPR013442 CRISPR-associated protein APE2256 VMUT_1483 72e8b340497c01885e4db613effa711e 293 Gene3D G3DSA:3.40.50.10770 58 233 1.2E-51 T 23-10-2018 VMUT_1749 117cbfcb4bf195c81ff54c6fe0e4d25c 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 1.2E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VMUT_1749 117cbfcb4bf195c81ff54c6fe0e4d25c 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 146 162 1.2E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VMUT_1749 117cbfcb4bf195c81ff54c6fe0e4d25c 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 164 184 1.2E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VMUT_1749 117cbfcb4bf195c81ff54c6fe0e4d25c 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 191 204 1.2E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VMUT_1749 117cbfcb4bf195c81ff54c6fe0e4d25c 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 115 128 1.2E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VMUT_1749 117cbfcb4bf195c81ff54c6fe0e4d25c 231 Gene3D G3DSA:1.10.150.240 15 95 1.6E-29 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 VMUT_1749 117cbfcb4bf195c81ff54c6fe0e4d25c 231 SUPERFAMILY SSF56784 1 229 2.91E-35 T 23-10-2018 IPR036412 HAD-like superfamily VMUT_1749 117cbfcb4bf195c81ff54c6fe0e4d25c 231 Gene3D G3DSA:3.40.50.1000 4 205 1.6E-29 T 23-10-2018 IPR023214 HAD superfamily VMUT_1749 117cbfcb4bf195c81ff54c6fe0e4d25c 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 96 202 1.5E-13 T 23-10-2018 VMUT_1749 117cbfcb4bf195c81ff54c6fe0e4d25c 231 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 64 201 1.8E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VMUT_0408 3afe969dca3fd0baf4eb2cab302f8d46 926 Pfam PF03065 Glycosyl hydrolase family 57 359 710 7.7E-48 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 VMUT_0408 3afe969dca3fd0baf4eb2cab302f8d46 926 Gene3D G3DSA:3.20.110.20 445 705 1.9E-31 T 23-10-2018 VMUT_0408 3afe969dca3fd0baf4eb2cab302f8d46 926 SUPERFAMILY SSF88713 354 684 1.49E-66 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 VMUT_1936 fd2d6144cf0c09aee8a4d5030f866e3b 443 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 419 37.862 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 VMUT_1936 fd2d6144cf0c09aee8a4d5030f866e3b 443 SUPERFAMILY SSF53271 219 423 7.46E-51 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like VMUT_1936 fd2d6144cf0c09aee8a4d5030f866e3b 443 Gene3D G3DSA:3.40.50.2020 243 404 9.6E-114 T 23-10-2018 VMUT_1936 fd2d6144cf0c09aee8a4d5030f866e3b 443 Gene3D G3DSA:3.60.20.10 3 421 9.6E-114 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VMUT_1936 fd2d6144cf0c09aee8a4d5030f866e3b 443 SUPERFAMILY SSF56235 2 203 5.75E-39 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VMUT_1936 fd2d6144cf0c09aee8a4d5030f866e3b 443 Pfam PF13537 Glutamine amidotransferase domain 71 183 3.9E-18 T 23-10-2018 IPR017932 Glutamine amidotransferase type 2 domain VMUT_1936 fd2d6144cf0c09aee8a4d5030f866e3b 443 PIRSF PIRSF000485 1 436 1.0E-119 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 VMUT_1852 0a0f8146a93e2fc3a79cf6ba3ad55db8 112 SUPERFAMILY SSF50249 10 111 1.4E-27 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold VMUT_1852 0a0f8146a93e2fc3a79cf6ba3ad55db8 112 Pfam PF01588 Putative tRNA binding domain 16 102 2.4E-26 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 VMUT_1852 0a0f8146a93e2fc3a79cf6ba3ad55db8 112 Gene3D G3DSA:2.40.50.140 2 112 2.4E-30 T 23-10-2018 VMUT_1852 0a0f8146a93e2fc3a79cf6ba3ad55db8 112 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 3 112 1.4E-35 T 23-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 VMUT_1465 1acbe81aaf62d341023f85301f475672 197 SMART SM00316 80 168 4.8E-13 T 23-10-2018 IPR022967 RNA-binding domain, S1 VMUT_1465 1acbe81aaf62d341023f85301f475672 197 SUPERFAMILY SSF88798 1 77 2.35E-19 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 VMUT_1465 1acbe81aaf62d341023f85301f475672 197 SUPERFAMILY SSF50249 81 182 3.21E-18 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold VMUT_1465 1acbe81aaf62d341023f85301f475672 197 Pfam PF00575 S1 RNA binding domain 81 152 1.3E-10 T 23-10-2018 IPR003029 S1 domain GO:0003676 VMUT_1465 1acbe81aaf62d341023f85301f475672 197 TIGRFAM TIGR00448 rpoE: DNA-directed RNA polymerase 1 181 3.3E-56 T 23-10-2018 IPR004519 DNA-directed RNA polymerase, subunit E/RPC8 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-1834949|Reactome: R-HSA-73780|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071 VMUT_1465 1acbe81aaf62d341023f85301f475672 197 Gene3D G3DSA:3.30.1490.120 1 81 2.2E-25 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 VMUT_1465 1acbe81aaf62d341023f85301f475672 197 Pfam PF03876 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 8 77 5.3E-14 T 23-10-2018 IPR005576 RNA polymerase Rpb7, N-terminal GO:0003899|GO:0006351 VMUT_1465 1acbe81aaf62d341023f85301f475672 197 Gene3D G3DSA:2.40.50.140 82 193 3.9E-21 T 23-10-2018 VMUT_1060 6a1bba6bb50ac87ebe13c71b3c5a35ab 237 SUPERFAMILY SSF52540 2 231 1.7E-14 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1060 6a1bba6bb50ac87ebe13c71b3c5a35ab 237 Gene3D G3DSA:3.40.50.300 4 232 3.8E-11 T 23-10-2018 VMUT_1590 b0b1783ac428188644d48d9b3238b750 359 SUPERFAMILY SSF51998 108 351 1.56E-7 T 23-10-2018 VMUT_1590 b0b1783ac428188644d48d9b3238b750 359 Pfam PF07282 Putative transposase DNA-binding domain 295 349 4.2E-10 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal VMUT_0589 0a49b32805ef35a41e17c34f5d730831 433 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 56 2.1E-5 T 23-10-2018 VMUT_0589 0a49b32805ef35a41e17c34f5d730831 433 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 198 223 2.0E-5 T 23-10-2018 VMUT_0589 0a49b32805ef35a41e17c34f5d730831 433 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 2.0E-5 T 23-10-2018 VMUT_0589 0a49b32805ef35a41e17c34f5d730831 433 SUPERFAMILY SSF51905 3 425 1.83E-33 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0589 0a49b32805ef35a41e17c34f5d730831 433 Gene3D G3DSA:3.50.50.60 2 92 2.4E-10 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0589 0a49b32805ef35a41e17c34f5d730831 433 Gene3D G3DSA:3.50.50.60 185 297 1.4E-10 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_2279 740143f5d8c9d0a63c6c279ea57a8d60 219 Gene3D G3DSA:3.40.50.300 1 218 1.4E-57 T 23-10-2018 VMUT_2279 740143f5d8c9d0a63c6c279ea57a8d60 219 SMART SM00382 10 189 1.6E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_2279 740143f5d8c9d0a63c6c279ea57a8d60 219 Pfam PF00005 ABC transporter 1 141 1.1E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_2279 740143f5d8c9d0a63c6c279ea57a8d60 219 SUPERFAMILY SSF52540 1 201 4.9E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0347 aa98ae96ba32686294aab93ee81b583f 186 Gene3D G3DSA:3.40.920.10 4 183 1.9E-53 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 VMUT_0347 aa98ae96ba32686294aab93ee81b583f 186 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 178 7.7E-36 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 VMUT_0347 aa98ae96ba32686294aab93ee81b583f 186 SUPERFAMILY SSF53323 6 182 1.19E-40 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 VMUT_0347 aa98ae96ba32686294aab93ee81b583f 186 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 6 181 1.0E-56 T 23-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 VMUT_0179 4f2f758a14afb4f9c45d32419e73865e 219 Pfam PF05239 PRC-barrel domain 15 60 4.3E-5 T 23-10-2018 IPR027275 PRC-barrel domain VMUT_1253 d88bd36bb324b778a61bc29a893fa67f 331 Gene3D G3DSA:3.40.980.10 145 302 1.3E-24 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily VMUT_1253 d88bd36bb324b778a61bc29a893fa67f 331 SMART SM00852 171 329 9.6E-12 T 23-10-2018 IPR001453 MoaB/Mog domain VMUT_1253 d88bd36bb324b778a61bc29a893fa67f 331 Pfam PF00994 Probable molybdopterin binding domain 171 277 5.1E-18 T 23-10-2018 IPR001453 MoaB/Mog domain VMUT_1253 d88bd36bb324b778a61bc29a893fa67f 331 SUPERFAMILY SSF53218 168 315 6.41E-26 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily VMUT_0390 8dfb4243c9623f405bdbd47f15407c00 403 PRINTS PR00477 Phosphoglycerate kinase family signature 179 201 1.7E-48 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VMUT_0390 8dfb4243c9623f405bdbd47f15407c00 403 PRINTS PR00477 Phosphoglycerate kinase family signature 372 389 1.7E-48 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VMUT_0390 8dfb4243c9623f405bdbd47f15407c00 403 PRINTS PR00477 Phosphoglycerate kinase family signature 15 31 1.7E-48 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VMUT_0390 8dfb4243c9623f405bdbd47f15407c00 403 PRINTS PR00477 Phosphoglycerate kinase family signature 349 360 1.7E-48 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VMUT_0390 8dfb4243c9623f405bdbd47f15407c00 403 PRINTS PR00477 Phosphoglycerate kinase family signature 38 60 1.7E-48 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VMUT_0390 8dfb4243c9623f405bdbd47f15407c00 403 PRINTS PR00477 Phosphoglycerate kinase family signature 114 129 1.7E-48 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VMUT_0390 8dfb4243c9623f405bdbd47f15407c00 403 PRINTS PR00477 Phosphoglycerate kinase family signature 316 341 1.7E-48 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VMUT_0390 8dfb4243c9623f405bdbd47f15407c00 403 PRINTS PR00477 Phosphoglycerate kinase family signature 149 171 1.7E-48 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VMUT_0390 8dfb4243c9623f405bdbd47f15407c00 403 PRINTS PR00477 Phosphoglycerate kinase family signature 202 221 1.7E-48 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VMUT_0390 8dfb4243c9623f405bdbd47f15407c00 403 Gene3D G3DSA:3.40.50.1260 19 393 1.5E-109 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VMUT_0390 8dfb4243c9623f405bdbd47f15407c00 403 SUPERFAMILY SSF53748 17 395 3.42E-103 T 23-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VMUT_0390 8dfb4243c9623f405bdbd47f15407c00 403 Pfam PF00162 Phosphoglycerate kinase 18 384 1.2E-100 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VMUT_0390 8dfb4243c9623f405bdbd47f15407c00 403 PIRSF PIRSF000724 8 402 2.4E-112 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VMUT_0390 8dfb4243c9623f405bdbd47f15407c00 403 Gene3D G3DSA:3.40.50.1260 198 386 1.5E-109 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VMUT_0390 8dfb4243c9623f405bdbd47f15407c00 403 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 12 396 31.917 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VMUT_1691 9d0d62c95e248d42983da1c998fcd743 338 SUPERFAMILY SSF54637 15 163 4.62E-36 T 23-10-2018 IPR029069 HotDog domain superfamily VMUT_1691 9d0d62c95e248d42983da1c998fcd743 338 Gene3D G3DSA:3.10.129.10 182 332 7.9E-42 T 23-10-2018 VMUT_1691 9d0d62c95e248d42983da1c998fcd743 338 SUPERFAMILY SSF54637 187 323 2.04E-36 T 23-10-2018 IPR029069 HotDog domain superfamily VMUT_1691 9d0d62c95e248d42983da1c998fcd743 338 Gene3D G3DSA:3.10.129.10 7 168 4.7E-41 T 23-10-2018 VMUT_1691 9d0d62c95e248d42983da1c998fcd743 338 Pfam PF03061 Thioesterase superfamily 38 109 1.6E-13 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 VMUT_1691 9d0d62c95e248d42983da1c998fcd743 338 Pfam PF03061 Thioesterase superfamily 200 270 4.5E-14 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 VMUT_0967 7767e79c4207262d2c227d5de28b00ea 508 Gene3D G3DSA:1.20.1730.10 33 504 1.1E-24 T 23-10-2018 IPR038377 Sodium/glucose symporter superfamily VMUT_0048 8ec9b89c0511322ff04173e5baad6bcc 124 Pfam PF07883 Cupin domain 44 111 1.4E-18 T 23-10-2018 IPR013096 Cupin 2, conserved barrel VMUT_0048 8ec9b89c0511322ff04173e5baad6bcc 124 SUPERFAMILY SSF51182 25 114 8.91E-26 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily VMUT_0048 8ec9b89c0511322ff04173e5baad6bcc 124 PRINTS PR00655 Auxin binding protein signature 5 24 3.9E-6 T 23-10-2018 IPR000526 Auxin-binding protein GO:0010011 VMUT_0048 8ec9b89c0511322ff04173e5baad6bcc 124 PRINTS PR00655 Auxin binding protein signature 49 73 3.9E-6 T 23-10-2018 IPR000526 Auxin-binding protein GO:0010011 VMUT_0048 8ec9b89c0511322ff04173e5baad6bcc 124 Gene3D G3DSA:2.60.120.10 3 117 1.3E-29 T 23-10-2018 IPR014710 RmlC-like jelly roll fold VMUT_1573 c1333ffd8de8671e65a81c9d7de0eaf9 288 PIRSF PIRSF004961 2 288 3.4E-93 T 23-10-2018 IPR011589 Protein of unknown function UCP004961 VMUT_1573 c1333ffd8de8671e65a81c9d7de0eaf9 288 Pfam PF01026 TatD related DNase 10 282 3.0E-21 T 23-10-2018 IPR001130 TatD family GO:0016788 VMUT_1573 c1333ffd8de8671e65a81c9d7de0eaf9 288 Gene3D G3DSA:3.20.20.140 8 287 2.7E-18 T 23-10-2018 VMUT_1573 c1333ffd8de8671e65a81c9d7de0eaf9 288 SUPERFAMILY SSF51556 7 285 9.95E-23 T 23-10-2018 IPR032466 Metal-dependent hydrolase VMUT_1573 c1333ffd8de8671e65a81c9d7de0eaf9 288 ProDom PD038341 HYDROLASE COFACTOR MOLYBDENUM BIOSYNTHESIS METAL-DEPENDENT DEOXYRIBONUCLEASE PREDICTED TATD-RELATED TVG0313409 A 107 283 9.0E-54 T 23-10-2018 VMUT_1163 9d01af0ac72cfc7315cb9d43b5e47a7b 636 Gene3D G3DSA:3.60.9.10 3 210 9.9E-72 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily VMUT_1163 9d01af0ac72cfc7315cb9d43b5e47a7b 636 SUPERFAMILY SSF48310 211 624 3.01E-95 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_1163 9d01af0ac72cfc7315cb9d43b5e47a7b 636 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 11 205 2.7E-67 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_1163 9d01af0ac72cfc7315cb9d43b5e47a7b 636 Gene3D G3DSA:1.10.599.10 241 623 6.1E-108 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 VMUT_1163 9d01af0ac72cfc7315cb9d43b5e47a7b 636 Gene3D G3DSA:1.10.569.10 243 435 6.1E-108 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 VMUT_1163 9d01af0ac72cfc7315cb9d43b5e47a7b 636 SMART SM00790 6 207 2.1E-92 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_1163 9d01af0ac72cfc7315cb9d43b5e47a7b 636 SUPERFAMILY SSF56228 5 208 6.67E-61 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily VMUT_1163 9d01af0ac72cfc7315cb9d43b5e47a7b 636 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 235 623 5.7E-100 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_0086 fd42bd6165fbbded3f91d59b072c8934 668 ProSitePatterns PS00455 Putative AMP-binding domain signature. 272 283 - T 23-10-2018 IPR020845 AMP-binding, conserved site VMUT_0086 fd42bd6165fbbded3f91d59b072c8934 668 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 24 654 1.5E-286 T 23-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 VMUT_0086 fd42bd6165fbbded3f91d59b072c8934 668 Pfam PF13193 AMP-binding enzyme C-terminal domain 544 622 6.3E-28 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VMUT_0086 fd42bd6165fbbded3f91d59b072c8934 668 SUPERFAMILY SSF56801 19 652 7.33E-177 T 23-10-2018 VMUT_0086 fd42bd6165fbbded3f91d59b072c8934 668 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 28 81 2.4E-19 T 23-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 VMUT_0086 fd42bd6165fbbded3f91d59b072c8934 668 Gene3D G3DSA:3.40.50.12780 61 529 6.8E-105 T 23-10-2018 VMUT_0086 fd42bd6165fbbded3f91d59b072c8934 668 Pfam PF00501 AMP-binding enzyme 92 535 6.7E-95 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VMUT_0086 fd42bd6165fbbded3f91d59b072c8934 668 Gene3D G3DSA:3.30.300.30 531 662 7.8E-31 T 23-10-2018 VMUT_2000 91ad761b8f00b39333cffbd88868b104 239 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 42 225 6.5E-17 T 23-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 VMUT_2000 91ad761b8f00b39333cffbd88868b104 239 Pfam PF02592 Putative vitamin uptake transporter 71 219 5.0E-24 T 23-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 VMUT_1547 4d81d51a3293c820a8d00bf318bfeff8 360 Gene3D G3DSA:3.90.1260.10 29 314 2.8E-121 T 23-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 VMUT_1547 4d81d51a3293c820a8d00bf318bfeff8 360 Gene3D G3DSA:3.40.50.620 1 136 2.8E-121 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_1547 4d81d51a3293c820a8d00bf318bfeff8 360 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 82 93 - T 23-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 VMUT_1547 4d81d51a3293c820a8d00bf318bfeff8 360 Hamap MF_00005 Argininosuccinate synthase [argG]. 1 359 39.391 T 23-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 VMUT_1547 4d81d51a3293c820a8d00bf318bfeff8 360 TIGRFAM TIGR00032 argG: argininosuccinate synthase 1 351 7.9E-124 T 23-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 VMUT_1547 4d81d51a3293c820a8d00bf318bfeff8 360 SUPERFAMILY SSF69864 136 359 2.35E-73 T 23-10-2018 VMUT_1547 4d81d51a3293c820a8d00bf318bfeff8 360 SUPERFAMILY SSF52402 1 169 1.58E-31 T 23-10-2018 VMUT_1547 4d81d51a3293c820a8d00bf318bfeff8 360 Pfam PF00764 Arginosuccinate synthase 1 351 1.1E-128 T 23-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 VMUT_1074 a9a8baaa5111c7f0f6a0aca53279773f 225 Gene3D G3DSA:3.40.50.150 30 212 7.2E-24 T 23-10-2018 VMUT_1074 a9a8baaa5111c7f0f6a0aca53279773f 225 Pfam PF05050 Methyltransferase FkbM domain 37 199 4.1E-9 T 23-10-2018 IPR006342 Methyltransferase FkbM VMUT_1074 a9a8baaa5111c7f0f6a0aca53279773f 225 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 35 177 2.7E-20 T 23-10-2018 IPR006342 Methyltransferase FkbM VMUT_1074 a9a8baaa5111c7f0f6a0aca53279773f 225 SUPERFAMILY SSF53335 18 207 9.93E-32 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_1669 d4adf73a597777ba89242c861ee01b6f 113 Gene3D G3DSA:1.10.10.10 37 113 1.8E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_1669 d4adf73a597777ba89242c861ee01b6f 113 Pfam PF03297 S25 ribosomal protein 13 103 8.3E-19 T 23-10-2018 IPR004977 Ribosomal protein S25 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1669 d4adf73a597777ba89242c861ee01b6f 113 ProDom PD012268 RIBOSOMAL S25 40S RIBONUCLEOPROTEIN S25 MULTIGENE FAMILY TRANSCRIPTION STRAIN DIRECT 42 103 0.005 T 23-10-2018 IPR004977 Ribosomal protein S25 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0617 10e97c5e073f1c9f13e1c365bbf22602 307 SMART SM00382 42 225 1.4E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0617 10e97c5e073f1c9f13e1c365bbf22602 307 SUPERFAMILY SSF52540 30 249 2.83E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0617 10e97c5e073f1c9f13e1c365bbf22602 307 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VMUT_0617 10e97c5e073f1c9f13e1c365bbf22602 307 Gene3D G3DSA:3.40.50.300 7 254 6.1E-60 T 23-10-2018 VMUT_0617 10e97c5e073f1c9f13e1c365bbf22602 307 Pfam PF00005 ABC transporter 33 177 4.3E-25 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_1438 35248fd55b6ea455d9ada5c3d411ad79 187 PRINTS PR00097 Anthranilate synthase component II signature 75 86 6.3E-9 T 23-10-2018 VMUT_1438 35248fd55b6ea455d9ada5c3d411ad79 187 PRINTS PR00097 Anthranilate synthase component II signature 162 175 6.3E-9 T 23-10-2018 VMUT_1438 35248fd55b6ea455d9ada5c3d411ad79 187 PRINTS PR00097 Anthranilate synthase component II signature 46 55 6.3E-9 T 23-10-2018 VMUT_1438 35248fd55b6ea455d9ada5c3d411ad79 187 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 43 57 4.3E-6 T 23-10-2018 VMUT_1438 35248fd55b6ea455d9ada5c3d411ad79 187 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 75 91 4.3E-6 T 23-10-2018 VMUT_1438 35248fd55b6ea455d9ada5c3d411ad79 187 Pfam PF00117 Glutamine amidotransferase class-I 5 183 9.6E-31 T 23-10-2018 IPR017926 Glutamine amidotransferase VMUT_1438 35248fd55b6ea455d9ada5c3d411ad79 187 Gene3D G3DSA:3.40.50.880 1 187 2.9E-44 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like VMUT_1438 35248fd55b6ea455d9ada5c3d411ad79 187 PRINTS PR00096 Glutamine amidotransferase superfamily signature 46 55 4.6E-10 T 23-10-2018 VMUT_1438 35248fd55b6ea455d9ada5c3d411ad79 187 PRINTS PR00096 Glutamine amidotransferase superfamily signature 75 86 4.6E-10 T 23-10-2018 VMUT_1438 35248fd55b6ea455d9ada5c3d411ad79 187 PRINTS PR00096 Glutamine amidotransferase superfamily signature 162 175 4.6E-10 T 23-10-2018 VMUT_1438 35248fd55b6ea455d9ada5c3d411ad79 187 SUPERFAMILY SSF52317 2 186 3.3E-45 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like VMUT_1329 9ead83f194a75d9eaca875dfdf6d0827 158 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 7 146 1.3E-20 T 23-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VMUT_1329 9ead83f194a75d9eaca875dfdf6d0827 158 Gene3D G3DSA:1.20.1300.10 17 158 8.4E-7 T 23-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VMUT_1329 9ead83f194a75d9eaca875dfdf6d0827 158 SUPERFAMILY SSF81343 15 156 3.27E-10 T 23-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VMUT_1518 616c9af32ce65f4e7f11386561b4d8dd 337 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 2 332 1.4E-99 T 23-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 VMUT_1518 616c9af32ce65f4e7f11386561b4d8dd 337 SMART SM01329 2 332 8.0E-171 T 23-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 VMUT_1518 616c9af32ce65f4e7f11386561b4d8dd 337 SUPERFAMILY SSF53659 2 336 4.22E-117 T 23-10-2018 VMUT_1518 616c9af32ce65f4e7f11386561b4d8dd 337 TIGRFAM TIGR02088 LEU3_arch: isopropylmalate/isohomocitrate dehydrogenases 3 333 4.6E-125 T 23-10-2018 IPR011828 Isopropylmalate/isohomocitrate dehydrogenase GO:0003862|GO:0009098|GO:0051287|GO:0055114 VMUT_1518 616c9af32ce65f4e7f11386561b4d8dd 337 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 221 240 - T 23-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 VMUT_1518 616c9af32ce65f4e7f11386561b4d8dd 337 Gene3D G3DSA:3.40.718.10 1 337 2.5E-136 T 23-10-2018 VMUT_0629 b473ea32af2258f6d644d197ac78cc64 309 Gene3D G3DSA:2.40.10.120 7 210 2.1E-65 T 23-10-2018 VMUT_0629 b473ea32af2258f6d644d197ac78cc64 309 Pfam PF13180 PDZ domain 238 308 4.3E-10 T 23-10-2018 IPR001478 PDZ domain GO:0005515 VMUT_0629 b473ea32af2258f6d644d197ac78cc64 309 Pfam PF13365 Trypsin-like peptidase domain 43 180 3.5E-32 T 23-10-2018 VMUT_0629 b473ea32af2258f6d644d197ac78cc64 309 SMART SM00228 216 300 1.5E-9 T 23-10-2018 IPR001478 PDZ domain GO:0005515 VMUT_0629 b473ea32af2258f6d644d197ac78cc64 309 SUPERFAMILY SSF50494 9 213 2.79E-58 T 23-10-2018 IPR009003 Peptidase S1, PA clan VMUT_0629 b473ea32af2258f6d644d197ac78cc64 309 PRINTS PR00834 HtrA/DegQ protease family signature 151 168 9.7E-38 T 23-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VMUT_0629 b473ea32af2258f6d644d197ac78cc64 309 PRINTS PR00834 HtrA/DegQ protease family signature 113 137 9.7E-38 T 23-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VMUT_0629 b473ea32af2258f6d644d197ac78cc64 309 PRINTS PR00834 HtrA/DegQ protease family signature 256 268 9.7E-38 T 23-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VMUT_0629 b473ea32af2258f6d644d197ac78cc64 309 PRINTS PR00834 HtrA/DegQ protease family signature 173 190 9.7E-38 T 23-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VMUT_0629 b473ea32af2258f6d644d197ac78cc64 309 PRINTS PR00834 HtrA/DegQ protease family signature 51 63 9.7E-38 T 23-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VMUT_0629 b473ea32af2258f6d644d197ac78cc64 309 PRINTS PR00834 HtrA/DegQ protease family signature 72 92 9.7E-38 T 23-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VMUT_0629 b473ea32af2258f6d644d197ac78cc64 309 SUPERFAMILY SSF50156 187 300 2.1E-17 T 23-10-2018 IPR036034 PDZ superfamily GO:0005515 VMUT_0629 b473ea32af2258f6d644d197ac78cc64 309 Gene3D G3DSA:2.30.42.10 211 309 2.3E-21 T 23-10-2018 VMUT_0789 cf8b7fc1e574491d0ec5090976f8627d 340 Pfam PF04055 Radical SAM superfamily 4 141 1.0E-13 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_0789 cf8b7fc1e574491d0ec5090976f8627d 340 Pfam PF13186 Iron-sulfur cluster-binding domain 238 312 2.4E-12 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain VMUT_0789 cf8b7fc1e574491d0ec5090976f8627d 340 Gene3D G3DSA:3.20.20.70 2 304 3.8E-39 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_0789 cf8b7fc1e574491d0ec5090976f8627d 340 SUPERFAMILY SSF102114 2 310 3.92E-38 T 23-10-2018 VMUT_0870 32e2b9045f503e62ea63e31201fe2a2e 293 PIRSF PIRSF001365 1 293 1.3E-47 T 23-10-2018 IPR002220 DapA-like GO:0016829 VMUT_0870 32e2b9045f503e62ea63e31201fe2a2e 293 SMART SM01130 2 289 3.0E-41 T 23-10-2018 IPR002220 DapA-like GO:0016829 VMUT_0870 32e2b9045f503e62ea63e31201fe2a2e 293 SUPERFAMILY SSF51569 2 291 2.93E-58 T 23-10-2018 VMUT_0870 32e2b9045f503e62ea63e31201fe2a2e 293 Pfam PF00701 Dihydrodipicolinate synthetase family 3 281 2.5E-37 T 23-10-2018 IPR002220 DapA-like GO:0016829 VMUT_0870 32e2b9045f503e62ea63e31201fe2a2e 293 Gene3D G3DSA:3.20.20.70 1 289 1.6E-58 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_1766 dd7790de1811bce4e3cbeb2491c82cc7 342 ProSitePatterns PS00474 Ribosomal protein L3 signature. 196 219 - T 23-10-2018 IPR019926 Ribosomal protein L3, conserved site VMUT_1766 dd7790de1811bce4e3cbeb2491c82cc7 342 Gene3D G3DSA:2.40.30.10 42 319 2.8E-108 T 23-10-2018 VMUT_1766 dd7790de1811bce4e3cbeb2491c82cc7 342 TIGRFAM TIGR03626 L3_arch: ribosomal protein uL3 6 337 5.1E-125 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_1766 dd7790de1811bce4e3cbeb2491c82cc7 342 SUPERFAMILY SSF50447 4 339 3.27E-83 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VMUT_1766 dd7790de1811bce4e3cbeb2491c82cc7 342 Gene3D G3DSA:3.30.1430.10 81 191 2.8E-108 T 23-10-2018 VMUT_1766 dd7790de1811bce4e3cbeb2491c82cc7 342 Pfam PF00297 Ribosomal protein L3 4 340 1.3E-68 T 23-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_1766 dd7790de1811bce4e3cbeb2491c82cc7 342 Hamap MF_01325_A 50S ribosomal protein L3 [rplC]. 1 340 45.155 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_1766 dd7790de1811bce4e3cbeb2491c82cc7 342 Gene3D G3DSA:4.10.960.10 7 259 2.8E-108 T 23-10-2018 VMUT_0785 e21e2b47c3d5f894d68834dd252fa6f3 298 PIRSF PIRSF036979 23 298 8.2E-54 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 VMUT_0785 e21e2b47c3d5f894d68834dd252fa6f3 298 Pfam PF00491 Arginase family 32 291 4.1E-59 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 VMUT_0785 e21e2b47c3d5f894d68834dd252fa6f3 298 Gene3D G3DSA:3.40.800.10 26 296 1.7E-65 T 23-10-2018 VMUT_0785 e21e2b47c3d5f894d68834dd252fa6f3 298 SUPERFAMILY SSF52768 27 294 1.35E-68 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily VMUT_1982 2c931379c9b602334521673f0722fd02 138 Gene3D G3DSA:3.30.460.10 2 121 1.9E-18 T 23-10-2018 VMUT_1982 2c931379c9b602334521673f0722fd02 138 Pfam PF01909 Nucleotidyltransferase domain 25 89 8.6E-9 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 VMUT_1982 2c931379c9b602334521673f0722fd02 138 SUPERFAMILY SSF81301 7 115 4.53E-19 T 23-10-2018 VMUT_0690 15f6aadd1a847a0e8854e09039cb7452 219 PRINTS PR00141 Proteasome component signature 186 197 7.2E-11 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 VMUT_0690 15f6aadd1a847a0e8854e09039cb7452 219 PRINTS PR00141 Proteasome component signature 26 41 7.2E-11 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 VMUT_0690 15f6aadd1a847a0e8854e09039cb7452 219 PRINTS PR00141 Proteasome component signature 150 161 7.2E-11 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 VMUT_0690 15f6aadd1a847a0e8854e09039cb7452 219 PRINTS PR00141 Proteasome component signature 161 172 7.2E-11 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 VMUT_0690 15f6aadd1a847a0e8854e09039cb7452 219 SUPERFAMILY SSF56235 12 210 1.2E-55 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VMUT_0690 15f6aadd1a847a0e8854e09039cb7452 219 Hamap MF_02113_A Proteasome subunit beta [prcB]. 14 213 33.846 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 VMUT_0690 15f6aadd1a847a0e8854e09039cb7452 219 Pfam PF00227 Proteasome subunit 17 200 2.9E-48 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 VMUT_0690 15f6aadd1a847a0e8854e09039cb7452 219 Gene3D G3DSA:3.60.20.10 5 218 2.5E-59 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VMUT_1570 0bec7ec983a3f0e5f0d04160e3910634 442 Gene3D G3DSA:3.30.590.10 110 439 5.4E-100 T 23-10-2018 VMUT_1570 0bec7ec983a3f0e5f0d04160e3910634 442 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 22 98 1.4E-11 T 23-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 VMUT_1570 0bec7ec983a3f0e5f0d04160e3910634 442 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 232 247 - T 23-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 VMUT_1570 0bec7ec983a3f0e5f0d04160e3910634 442 Gene3D G3DSA:3.10.20.70 10 107 2.3E-17 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 VMUT_1570 0bec7ec983a3f0e5f0d04160e3910634 442 Pfam PF00120 Glutamine synthetase, catalytic domain 109 427 2.6E-97 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 VMUT_1570 0bec7ec983a3f0e5f0d04160e3910634 442 SUPERFAMILY SSF54368 11 105 7.85E-20 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 VMUT_1570 0bec7ec983a3f0e5f0d04160e3910634 442 SUPERFAMILY SSF55931 108 427 2.01E-100 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 VMUT_1570 0bec7ec983a3f0e5f0d04160e3910634 442 SMART SM01230 107 350 2.1E-99 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 VMUT_0214 7f076f3053affee0ce9693a43a4e9f4d 343 SUPERFAMILY SSF48576 14 342 2.88E-69 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily VMUT_0214 7f076f3053affee0ce9693a43a4e9f4d 343 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 221 233 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site VMUT_0214 7f076f3053affee0ce9693a43a4e9f4d 343 Gene3D G3DSA:1.10.600.10 1 343 1.3E-103 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily VMUT_0214 7f076f3053affee0ce9693a43a4e9f4d 343 Pfam PF00348 Polyprenyl synthetase 31 295 1.4E-52 T 23-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 VMUT_1857 38ce91fdeb34c3613070c8d99b08d884 582 Gene3D G3DSA:3.20.110.20 93 445 1.5E-21 T 23-10-2018 VMUT_1857 38ce91fdeb34c3613070c8d99b08d884 582 SUPERFAMILY SSF88713 94 418 2.63E-41 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 VMUT_1857 38ce91fdeb34c3613070c8d99b08d884 582 Pfam PF03065 Glycosyl hydrolase family 57 99 428 2.1E-38 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 VMUT_0524 3cc00719db1877cdc24931144894f627 82 SUPERFAMILY SSF64307 9 77 6.93E-19 T 23-10-2018 IPR036868 TusA-like domain superfamily VMUT_0524 3cc00719db1877cdc24931144894f627 82 Pfam PF01206 Sulfurtransferase TusA 11 77 9.2E-19 T 23-10-2018 IPR001455 TusA-like domain VMUT_0524 3cc00719db1877cdc24931144894f627 82 Gene3D G3DSA:3.30.110.40 5 79 1.3E-24 T 23-10-2018 IPR036868 TusA-like domain superfamily VMUT_0273 1607cc507c325e2ca64116132cc032b3 148 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 6 132 1.2E-8 T 23-10-2018 IPR005519 Acid phosphatase, class B-like VMUT_0273 1607cc507c325e2ca64116132cc032b3 148 Gene3D G3DSA:3.40.50.1000 5 148 8.9E-28 T 23-10-2018 IPR023214 HAD superfamily VMUT_0273 1607cc507c325e2ca64116132cc032b3 148 SUPERFAMILY SSF56784 4 145 3.34E-15 T 23-10-2018 IPR036412 HAD-like superfamily VMUT_0039 4279c925393155d3cd2ec8f86ea08246 87 SUPERFAMILY SSF55248 7 82 9.03E-26 T 23-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 VMUT_0039 4279c925393155d3cd2ec8f86ea08246 87 Gene3D G3DSA:3.30.1360.20 1 87 1.6E-28 T 23-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 VMUT_0039 4279c925393155d3cd2ec8f86ea08246 87 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 6 80 7.6E-26 T 23-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 VMUT_1765 8111ac71e70ac2c8193454ebd5c8dc40 292 Gene3D G3DSA:3.40.1280.10 18 283 1.6E-67 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal VMUT_1765 8111ac71e70ac2c8193454ebd5c8dc40 292 Gene3D G3DSA:2.40.50.140 113 177 1.6E-67 T 23-10-2018 VMUT_1765 8111ac71e70ac2c8193454ebd5c8dc40 292 SUPERFAMILY SSF50249 108 183 3.43E-5 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold VMUT_1765 8111ac71e70ac2c8193454ebd5c8dc40 292 Pfam PF02598 Putative RNA methyltransferase 17 281 1.0E-53 T 23-10-2018 IPR003750 Putative RNA methyltransferase VMUT_1765 8111ac71e70ac2c8193454ebd5c8dc40 292 SUPERFAMILY SSF75217 17 285 3.66E-33 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases VMUT_1274 03aa44908f577a273015860ae9ce1bae 170 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 39 69 6.3E-11 T 23-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal VMUT_1274 03aa44908f577a273015860ae9ce1bae 170 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 75 151 1.2E-14 T 23-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal VMUT_1274 03aa44908f577a273015860ae9ce1bae 170 SUPERFAMILY SSF50249 14 155 3.43E-29 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold VMUT_1274 03aa44908f577a273015860ae9ce1bae 170 Gene3D G3DSA:1.10.12.20 8 78 2.0E-22 T 23-10-2018 VMUT_0200 bb6852cfb72d7ea9192822cd5e57df33 427 SUPERFAMILY SSF51556 57 343 2.83E-83 T 23-10-2018 IPR032466 Metal-dependent hydrolase VMUT_0200 bb6852cfb72d7ea9192822cd5e57df33 427 Gene3D G3DSA:3.20.20.140 58 342 2.6E-114 T 23-10-2018 VMUT_0200 bb6852cfb72d7ea9192822cd5e57df33 427 Gene3D G3DSA:2.30.40.10 11 403 2.6E-114 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VMUT_0200 bb6852cfb72d7ea9192822cd5e57df33 427 SUPERFAMILY SSF51338 4 415 5.19E-22 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VMUT_0200 bb6852cfb72d7ea9192822cd5e57df33 427 Pfam PF01979 Amidohydrolase family 54 397 9.7E-56 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VMUT_2163 f7ce2702a1f499f73ca1ecad168ddb67 291 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 78 86 - T 23-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 VMUT_2163 f7ce2702a1f499f73ca1ecad168ddb67 291 SMART SM00518 15 281 4.4E-53 T 23-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 VMUT_2163 f7ce2702a1f499f73ca1ecad168ddb67 291 SUPERFAMILY SSF51658 12 288 5.24E-57 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily VMUT_2163 f7ce2702a1f499f73ca1ecad168ddb67 291 Gene3D G3DSA:3.20.20.150 20 289 3.4E-42 T 23-10-2018 VMUT_2163 f7ce2702a1f499f73ca1ecad168ddb67 291 Pfam PF01261 Xylose isomerase-like TIM barrel 36 242 8.8E-25 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain VMUT_2325 7355cf8a018b5dbc8a6e7c01bf543329 149 SUPERFAMILY SSF88697 72 146 1.89E-17 T 23-10-2018 IPR015947 PUA-like superfamily VMUT_2325 7355cf8a018b5dbc8a6e7c01bf543329 149 SUPERFAMILY SSF88802 7 71 9.15E-11 T 23-10-2018 VMUT_2325 7355cf8a018b5dbc8a6e7c01bf543329 149 Pfam PF01472 PUA domain 73 142 3.4E-16 T 23-10-2018 IPR002478 PUA domain GO:0003723 VMUT_2325 7355cf8a018b5dbc8a6e7c01bf543329 149 SMART SM00359 71 144 6.8E-13 T 23-10-2018 IPR002478 PUA domain GO:0003723 VMUT_2325 7355cf8a018b5dbc8a6e7c01bf543329 149 Gene3D G3DSA:3.10.450.90 3 71 5.6E-11 T 23-10-2018 IPR038250 TGT, patch-forming C2 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 VMUT_2325 7355cf8a018b5dbc8a6e7c01bf543329 149 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 9 71 2.0E-11 T 23-10-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 VMUT_2325 7355cf8a018b5dbc8a6e7c01bf543329 149 Gene3D G3DSA:2.30.130.10 72 144 7.1E-22 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 VMUT_2325 7355cf8a018b5dbc8a6e7c01bf543329 149 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 70 145 4.9E-11 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 VMUT_0453 3ecf6f5a0cdb19f018ab2802cc9ed266 164 Pfam PF01613 Flavin reductase like domain 12 158 2.7E-41 T 23-10-2018 IPR002563 Flavin reductase like domain GO:0010181 VMUT_0453 3ecf6f5a0cdb19f018ab2802cc9ed266 164 SUPERFAMILY SSF50475 9 158 3.48E-48 T 23-10-2018 VMUT_0453 3ecf6f5a0cdb19f018ab2802cc9ed266 164 Gene3D G3DSA:2.30.110.10 1 161 1.1E-50 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 VMUT_0453 3ecf6f5a0cdb19f018ab2802cc9ed266 164 SMART SM00903 12 156 3.5E-56 T 23-10-2018 IPR002563 Flavin reductase like domain GO:0010181 VMUT_0109 81b2d529a3f82358b74e9f720538b23c 275 Gene3D G3DSA:3.60.21.10 4 272 8.9E-77 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like VMUT_0109 81b2d529a3f82358b74e9f720538b23c 275 ProSitePatterns PS00125 Serine/threonine specific protein phosphatases signature. 94 99 - T 23-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VMUT_0109 81b2d529a3f82358b74e9f720538b23c 275 Pfam PF00149 Calcineurin-like phosphoesterase 35 228 4.9E-31 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 VMUT_0109 81b2d529a3f82358b74e9f720538b23c 275 SUPERFAMILY SSF56300 8 248 1.09E-66 T 23-10-2018 VMUT_0109 81b2d529a3f82358b74e9f720538b23c 275 PRINTS PR00114 Serine/threonine phosphatase family signature 93 117 1.6E-30 T 23-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VMUT_0109 81b2d529a3f82358b74e9f720538b23c 275 PRINTS PR00114 Serine/threonine phosphatase family signature 219 239 1.6E-30 T 23-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VMUT_0109 81b2d529a3f82358b74e9f720538b23c 275 PRINTS PR00114 Serine/threonine phosphatase family signature 131 157 1.6E-30 T 23-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VMUT_0109 81b2d529a3f82358b74e9f720538b23c 275 PRINTS PR00114 Serine/threonine phosphatase family signature 160 187 1.6E-30 T 23-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VMUT_0109 81b2d529a3f82358b74e9f720538b23c 275 PRINTS PR00114 Serine/threonine phosphatase family signature 34 61 1.6E-30 T 23-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VMUT_0109 81b2d529a3f82358b74e9f720538b23c 275 SMART SM00156 5 267 5.1E-63 T 23-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VMUT_1584 8af1b5ff2c0fb0d8071be970f723c788 536 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 14 225 3.0E-56 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 VMUT_1584 8af1b5ff2c0fb0d8071be970f723c788 536 Pfam PF01256 Carbohydrate kinase 255 511 1.5E-50 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 VMUT_1584 8af1b5ff2c0fb0d8071be970f723c788 536 Gene3D G3DSA:3.40.1190.20 237 532 1.8E-76 T 23-10-2018 IPR029056 Ribokinase-like VMUT_1584 8af1b5ff2c0fb0d8071be970f723c788 536 PIRSF PIRSF017184 11 521 1.5E-113 T 23-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 VMUT_1584 8af1b5ff2c0fb0d8071be970f723c788 536 SUPERFAMILY SSF64153 13 253 8.11E-59 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 VMUT_1584 8af1b5ff2c0fb0d8071be970f723c788 536 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 231 515 1.1E-66 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 VMUT_1584 8af1b5ff2c0fb0d8071be970f723c788 536 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 14 224 24.741 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 VMUT_1584 8af1b5ff2c0fb0d8071be970f723c788 536 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 454 464 - T 23-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site VMUT_1584 8af1b5ff2c0fb0d8071be970f723c788 536 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 232 518 21.949 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 VMUT_1584 8af1b5ff2c0fb0d8071be970f723c788 536 Pfam PF03853 YjeF-related protein N-terminus 33 203 3.2E-41 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 VMUT_1584 8af1b5ff2c0fb0d8071be970f723c788 536 SUPERFAMILY SSF53613 237 515 2.76E-63 T 23-10-2018 IPR029056 Ribokinase-like VMUT_1584 8af1b5ff2c0fb0d8071be970f723c788 536 Gene3D G3DSA:3.40.50.10260 9 230 4.4E-61 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 VMUT_2027 ec50910d18f5f43812243984d6fca010 1141 SUPERFAMILY SSF52540 27 288 1.2E-7 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_2027 ec50910d18f5f43812243984d6fca010 1141 Gene3D G3DSA:1.20.120.20 840 974 3.0E-5 T 23-10-2018 VMUT_1855 f16504bdb2b68cdb817a41e3f96129de 195 SUPERFAMILY SSF53756 3 185 1.18E-16 T 23-10-2018 VMUT_1855 f16504bdb2b68cdb817a41e3f96129de 195 Pfam PF13439 Glycosyltransferase Family 4 23 174 9.4E-11 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 VMUT_1855 f16504bdb2b68cdb817a41e3f96129de 195 Gene3D G3DSA:3.40.50.2000 2 186 4.4E-14 T 23-10-2018 VMUT_2287 cd07b188447a491bc03e6d55c8333eab 630 Pfam PF00723 Glycosyl hydrolases family 15 247 288 4.5E-8 T 23-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 VMUT_2287 cd07b188447a491bc03e6d55c8333eab 630 Gene3D G3DSA:1.50.10.10 239 603 6.1E-62 T 23-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 VMUT_2287 cd07b188447a491bc03e6d55c8333eab 630 SUPERFAMILY SSF48208 208 594 2.0E-69 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 VMUT_0325 b3b7394993aa2e08d5ad55441d9fbf83 268 SUPERFAMILY SSF55729 13 258 9.43E-20 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase VMUT_0325 b3b7394993aa2e08d5ad55441d9fbf83 268 Pfam PF08445 FR47-like protein 177 258 2.1E-12 T 23-10-2018 IPR013653 FR47-like GO:0016747 VMUT_0325 b3b7394993aa2e08d5ad55441d9fbf83 268 Gene3D G3DSA:3.40.630.30 104 261 2.0E-19 T 23-10-2018 VMUT_1861 49ef948ea31b8d01f783872b04ddc15e 150 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 14 138 2.0E-12 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 VMUT_1861 49ef948ea31b8d01f783872b04ddc15e 150 SUPERFAMILY SSF55620 10 143 6.67E-20 T 23-10-2018 VMUT_1861 49ef948ea31b8d01f783872b04ddc15e 150 Gene3D G3DSA:3.30.479.10 7 144 1.7E-13 T 23-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 VMUT_0461 eca331995cda0df76a8bb5e07dafc956 122 Pfam PF01984 Double-stranded DNA-binding domain 25 120 2.1E-23 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 VMUT_0461 eca331995cda0df76a8bb5e07dafc956 122 Hamap MF_00026 DNA-binding protein . 20 121 16.499 T 23-10-2018 IPR022889 DNA-binding protein, archaeal VMUT_0461 eca331995cda0df76a8bb5e07dafc956 122 SUPERFAMILY SSF46950 25 120 6.15E-27 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 VMUT_0461 eca331995cda0df76a8bb5e07dafc956 122 Gene3D G3DSA:1.10.8.140 42 122 1.3E-25 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 VMUT_0461 eca331995cda0df76a8bb5e07dafc956 122 PIRSF PIRSF015730 16 122 6.2E-31 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 VMUT_2250 51eff2c44fe1df32be88a23a73329257 114 Pfam PF03061 Thioesterase superfamily 1 84 1.1E-14 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 VMUT_2250 51eff2c44fe1df32be88a23a73329257 114 Gene3D G3DSA:3.10.129.10 1 114 1.1E-29 T 23-10-2018 VMUT_2250 51eff2c44fe1df32be88a23a73329257 114 SUPERFAMILY SSF54637 1 111 1.91E-29 T 23-10-2018 IPR029069 HotDog domain superfamily VMUT_2250 51eff2c44fe1df32be88a23a73329257 114 PIRSF PIRSF003230 1 114 1.0E-22 T 23-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 VMUT_0758 67f4d864788d5980df3d4e83c78821f7 81 Pfam PF01200 Ribosomal protein S28e 16 78 2.0E-29 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0758 67f4d864788d5980df3d4e83c78821f7 81 Hamap MF_00292 30S ribosomal protein S28e [rps28e]. 1 79 24.731 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0758 67f4d864788d5980df3d4e83c78821f7 81 ProSitePatterns PS00961 Ribosomal protein S28e signature. 70 78 - T 23-10-2018 IPR028626 Ribosomal protein S28e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0758 67f4d864788d5980df3d4e83c78821f7 81 SUPERFAMILY SSF50249 14 79 2.23E-24 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold VMUT_0758 67f4d864788d5980df3d4e83c78821f7 81 Gene3D G3DSA:2.40.50.140 14 80 8.1E-30 T 23-10-2018 VMUT_0758 67f4d864788d5980df3d4e83c78821f7 81 ProDom PD005541 RIBOSOMAL RIBONUCLEOPROTEIN 40S S28 S28E 30S ACETYLATION S33 S33 CG15527 22 60 1.0E-11 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0438 28b39b4bc5a292e259b1c623856ddc8b 196 Gene3D G3DSA:3.90.79.10 2 184 1.4E-28 T 23-10-2018 VMUT_0438 28b39b4bc5a292e259b1c623856ddc8b 196 SUPERFAMILY SSF55811 5 181 3.38E-24 T 23-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 VMUT_0438 28b39b4bc5a292e259b1c623856ddc8b 196 Pfam PF00293 NUDIX domain 27 145 2.3E-13 T 23-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 VMUT_0829 94c5d0083fbddc43809f3afe977e90f3 452 Pfam PF00202 Aminotransferase class-III 50 443 6.3E-59 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VMUT_0829 94c5d0083fbddc43809f3afe977e90f3 452 PIRSF PIRSF000521 44 157 1.2 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VMUT_0829 94c5d0083fbddc43809f3afe977e90f3 452 PIRSF PIRSF000521 415 448 410.0 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VMUT_0829 94c5d0083fbddc43809f3afe977e90f3 452 PIRSF PIRSF000521 193 366 1.9E-10 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VMUT_0829 94c5d0083fbddc43809f3afe977e90f3 452 SUPERFAMILY SSF53383 23 448 5.33E-110 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VMUT_0829 94c5d0083fbddc43809f3afe977e90f3 452 Gene3D G3DSA:3.90.1150.10 28 439 4.9E-142 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VMUT_0829 94c5d0083fbddc43809f3afe977e90f3 452 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 248 284 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VMUT_0829 94c5d0083fbddc43809f3afe977e90f3 452 Gene3D G3DSA:3.40.640.10 88 338 4.9E-142 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VMUT_1595 9849624b6bc6ed62e1b247c62a09409a 385 Pfam PF07690 Major Facilitator Superfamily 225 378 6.5E-9 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_1595 9849624b6bc6ed62e1b247c62a09409a 385 Pfam PF07690 Major Facilitator Superfamily 34 217 9.8E-19 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_1595 9849624b6bc6ed62e1b247c62a09409a 385 Gene3D G3DSA:1.20.1250.20 4 380 1.0E-33 T 23-10-2018 VMUT_1595 9849624b6bc6ed62e1b247c62a09409a 385 ProSitePatterns PS00216 Sugar transport proteins signature 1. 56 72 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VMUT_1595 9849624b6bc6ed62e1b247c62a09409a 385 SUPERFAMILY SSF103473 27 379 6.67E-37 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_0327 481709ab0ae8be6200ade635caf48b18 478 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 77 370 6.7E-26 T 23-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 VMUT_0327 481709ab0ae8be6200ade635caf48b18 478 Gene3D G3DSA:3.90.1150.10 340 434 5.1E-120 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VMUT_0327 481709ab0ae8be6200ade635caf48b18 478 Gene3D G3DSA:3.40.640.10 112 339 5.1E-120 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VMUT_0327 481709ab0ae8be6200ade635caf48b18 478 SUPERFAMILY SSF53383 36 436 3.95E-104 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VMUT_2260 eb1b34989fe4442102eaee270d2818c1 135 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 15 23 3.6E-7 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_2260 eb1b34989fe4442102eaee270d2818c1 135 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 35 54 3.6E-7 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_2260 eb1b34989fe4442102eaee270d2818c1 135 SUPERFAMILY SSF51735 1 133 3.44E-47 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_2260 eb1b34989fe4442102eaee270d2818c1 135 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 22 50 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VMUT_2260 eb1b34989fe4442102eaee270d2818c1 135 Gene3D G3DSA:3.40.50.720 1 135 4.2E-48 T 23-10-2018 VMUT_2260 eb1b34989fe4442102eaee270d2818c1 135 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 116 1.6E-33 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_2260 eb1b34989fe4442102eaee270d2818c1 135 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 56 73 1.6E-33 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_2260 eb1b34989fe4442102eaee270d2818c1 135 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 35 54 1.6E-33 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_2260 eb1b34989fe4442102eaee270d2818c1 135 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 25 1.6E-33 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_2260 eb1b34989fe4442102eaee270d2818c1 135 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 1 130 5.3E-39 T 23-10-2018 VMUT_2079 6c1994fe38f672d9a93e67ebfea98628 272 PIRSF PIRSF001430 1 230 1.8E-51 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 VMUT_2079 6c1994fe38f672d9a93e67ebfea98628 272 Pfam PF01416 tRNA pseudouridine synthase 121 220 5.4E-14 T 23-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 VMUT_2079 6c1994fe38f672d9a93e67ebfea98628 272 SUPERFAMILY SSF55120 2 223 3.16E-49 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 VMUT_2079 6c1994fe38f672d9a93e67ebfea98628 272 Gene3D G3DSA:3.30.70.580 1 95 9.1E-16 T 23-10-2018 VMUT_2079 6c1994fe38f672d9a93e67ebfea98628 272 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 220 23.903 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 VMUT_2079 6c1994fe38f672d9a93e67ebfea98628 272 Gene3D G3DSA:3.30.70.660 96 219 1.1E-18 T 23-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 VMUT_2221 8f5212cf7fa3a0f0f721ed1165b9a259 685 Gene3D G3DSA:1.20.1250.20 10 201 1.3E-28 T 23-10-2018 VMUT_2221 8f5212cf7fa3a0f0f721ed1165b9a259 685 SUPERFAMILY SSF103473 8 554 2.35E-50 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_2221 8f5212cf7fa3a0f0f721ed1165b9a259 685 Pfam PF07690 Major Facilitator Superfamily 18 433 7.6E-39 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_2221 8f5212cf7fa3a0f0f721ed1165b9a259 685 Gene3D G3DSA:1.20.1250.20 281 551 3.4E-11 T 23-10-2018 VMUT_2217 eb1819cd45f13e0a44f128a685015ab6 463 SUPERFAMILY SSF53850 27 452 1.58E-33 T 23-10-2018 VMUT_2217 eb1819cd45f13e0a44f128a685015ab6 463 Pfam PF01547 Bacterial extracellular solute-binding protein 41 363 1.4E-14 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein VMUT_2217 eb1819cd45f13e0a44f128a685015ab6 463 Gene3D G3DSA:3.40.190.10 22 450 4.9E-38 T 23-10-2018 VMUT_1255 b3e548faf54c4eff57f4c1e7dfec007a 389 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 5 386 1.7E-151 T 23-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 VMUT_1762 fd1a3114f6c04d0344bacdd075a228b3 157 Gene3D G3DSA:3.100.10.10 66 153 1.5E-20 T 23-10-2018 VMUT_1762 fd1a3114f6c04d0344bacdd075a228b3 157 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 30 149 2.2E-20 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P VMUT_1762 fd1a3114f6c04d0344bacdd075a228b3 157 SUPERFAMILY SSF52080 7 151 3.14E-34 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily VMUT_1762 fd1a3114f6c04d0344bacdd075a228b3 157 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 2 151 14.252 T 23-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 VMUT_1762 fd1a3114f6c04d0344bacdd075a228b3 157 ProSitePatterns PS00475 Ribosomal protein L15 signature. 115 145 - T 23-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1762 fd1a3114f6c04d0344bacdd075a228b3 157 Gene3D G3DSA:4.10.990.10 5 55 4.7E-11 T 23-10-2018 IPR027386 50S ribosomal protein L15, N-terminal VMUT_0916 716482c52f3cffb3b347d294c2b04fba 450 Gene3D G3DSA:3.50.50.60 114 442 9.6E-154 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0916 716482c52f3cffb3b347d294c2b04fba 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 175 1.9E-20 T 23-10-2018 VMUT_0916 716482c52f3cffb3b347d294c2b04fba 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.9E-20 T 23-10-2018 VMUT_0916 716482c52f3cffb3b347d294c2b04fba 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 284 1.9E-20 T 23-10-2018 VMUT_0916 716482c52f3cffb3b347d294c2b04fba 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 236 250 1.9E-20 T 23-10-2018 VMUT_0916 716482c52f3cffb3b347d294c2b04fba 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 388 403 1.9E-20 T 23-10-2018 VMUT_0916 716482c52f3cffb3b347d294c2b04fba 450 SUPERFAMILY SSF55424 324 445 7.9E-27 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 VMUT_0916 716482c52f3cffb3b347d294c2b04fba 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 3.7E-33 T 23-10-2018 VMUT_0916 716482c52f3cffb3b347d294c2b04fba 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 3.7E-33 T 23-10-2018 VMUT_0916 716482c52f3cffb3b347d294c2b04fba 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 3.7E-33 T 23-10-2018 VMUT_0916 716482c52f3cffb3b347d294c2b04fba 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 3.7E-33 T 23-10-2018 VMUT_0916 716482c52f3cffb3b347d294c2b04fba 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 3.7E-33 T 23-10-2018 VMUT_0916 716482c52f3cffb3b347d294c2b04fba 450 Gene3D G3DSA:3.50.50.60 4 341 9.6E-154 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0916 716482c52f3cffb3b347d294c2b04fba 450 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 307 6.2E-63 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VMUT_0916 716482c52f3cffb3b347d294c2b04fba 450 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 331 432 5.4E-14 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 VMUT_0916 716482c52f3cffb3b347d294c2b04fba 450 SUPERFAMILY SSF51905 4 348 1.67E-51 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0631 bf84e249d8d287ed3a51f43dfa7066d0 105 ProDom PD005579 INITIATION FACTOR TRANSLATION 1A BIOSYNTHESIS EUKARYOTIC EIF-1A AIF-1A EIF-4C 1A 38 90 1.0E-13 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 VMUT_0631 bf84e249d8d287ed3a51f43dfa7066d0 105 SUPERFAMILY SSF50249 11 94 2.09E-26 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold VMUT_0631 bf84e249d8d287ed3a51f43dfa7066d0 105 Hamap MF_00216 Translation initiation factor 1A [eif1a]. 2 95 24.808 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 VMUT_0631 bf84e249d8d287ed3a51f43dfa7066d0 105 SMART SM00652 13 95 2.0E-32 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 VMUT_0631 bf84e249d8d287ed3a51f43dfa7066d0 105 ProSitePatterns PS01262 Eukaryotic initiation factor 1A signature. 26 48 - T 23-10-2018 IPR018104 Translation initiation factor 1A (eIF-1A), conserved site GO:0003743|GO:0006413 VMUT_0631 bf84e249d8d287ed3a51f43dfa7066d0 105 Gene3D G3DSA:2.40.50.140 2 102 7.0E-30 T 23-10-2018 VMUT_0631 bf84e249d8d287ed3a51f43dfa7066d0 105 Pfam PF01176 Translation initiation factor 1A / IF-1 17 79 2.6E-18 T 23-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 VMUT_1369 0a64ee952bf9615964aa4ae8fd567fb2 417 Gene3D G3DSA:1.10.540.10 7 130 3.2E-16 T 23-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VMUT_1369 0a64ee952bf9615964aa4ae8fd567fb2 417 SUPERFAMILY SSF56645 8 252 8.12E-40 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VMUT_1369 0a64ee952bf9615964aa4ae8fd567fb2 417 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 125 2.8E-11 T 23-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VMUT_1369 0a64ee952bf9615964aa4ae8fd567fb2 417 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 266 408 5.9E-26 T 23-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VMUT_1369 0a64ee952bf9615964aa4ae8fd567fb2 417 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 136 244 2.0E-11 T 23-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VMUT_1369 0a64ee952bf9615964aa4ae8fd567fb2 417 Gene3D G3DSA:1.20.140.10 261 415 1.3E-33 T 23-10-2018 VMUT_1369 0a64ee952bf9615964aa4ae8fd567fb2 417 Gene3D G3DSA:2.40.110.10 135 257 1.8E-22 T 23-10-2018 VMUT_1369 0a64ee952bf9615964aa4ae8fd567fb2 417 SUPERFAMILY SSF47203 265 413 8.05E-34 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VMUT_1234 454083392446a93cd2e90ee2314ad7e7 643 Gene3D G3DSA:3.40.50.970 230 441 3.3E-71 T 23-10-2018 VMUT_1234 454083392446a93cd2e90ee2314ad7e7 643 SUPERFAMILY SSF52518 241 508 5.11E-58 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold VMUT_1234 454083392446a93cd2e90ee2314ad7e7 643 Gene3D G3DSA:3.40.50.920 516 632 5.0E-32 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VMUT_1234 454083392446a93cd2e90ee2314ad7e7 643 SUPERFAMILY SSF53323 8 261 6.28E-18 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 VMUT_1234 454083392446a93cd2e90ee2314ad7e7 643 SUPERFAMILY SSF52922 520 636 1.31E-22 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VMUT_1234 454083392446a93cd2e90ee2314ad7e7 643 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 528 596 5.6E-9 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II VMUT_1234 454083392446a93cd2e90ee2314ad7e7 643 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 4 625 3.2E-177 T 23-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 VMUT_1234 454083392446a93cd2e90ee2314ad7e7 643 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 252 502 1.5E-56 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 VMUT_1234 454083392446a93cd2e90ee2314ad7e7 643 Gene3D G3DSA:3.40.920.10 1 229 1.5E-10 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 VMUT_1234 454083392446a93cd2e90ee2314ad7e7 643 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 220 2.6E-34 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 VMUT_1296 6889e6008f48874aafd96f696fb35a77 193 Gene3D G3DSA:3.30.1130.10 54 178 2.0E-34 T 23-10-2018 VMUT_1296 6889e6008f48874aafd96f696fb35a77 193 Gene3D G3DSA:1.10.286.10 2 48 4.7E-14 T 23-10-2018 VMUT_1296 6889e6008f48874aafd96f696fb35a77 193 Pfam PF01227 GTP cyclohydrolase I 4 172 1.7E-49 T 23-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 VMUT_1296 6889e6008f48874aafd96f696fb35a77 193 SUPERFAMILY SSF55620 2 171 4.3E-51 T 23-10-2018 VMUT_1169 4643fd7412ca2fcdb7db0824d009d27c 310 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 88 101 - T 23-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 VMUT_1169 4643fd7412ca2fcdb7db0824d009d27c 310 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 12 293 38.686 T 23-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 VMUT_1169 4643fd7412ca2fcdb7db0824d009d27c 310 Gene3D G3DSA:2.30.140.10 10 61 1.5E-14 T 23-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 VMUT_1169 4643fd7412ca2fcdb7db0824d009d27c 310 TIGRFAM TIGR00417 speE: spermidine synthase 13 286 1.3E-81 T 23-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 VMUT_1169 4643fd7412ca2fcdb7db0824d009d27c 310 SUPERFAMILY SSF53335 11 293 1.28E-87 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_1169 4643fd7412ca2fcdb7db0824d009d27c 310 Gene3D G3DSA:3.40.50.150 63 309 9.0E-88 T 23-10-2018 VMUT_1169 4643fd7412ca2fcdb7db0824d009d27c 310 Pfam PF01564 Spermine/spermidine synthase domain 67 246 1.1E-50 T 23-10-2018 VMUT_1169 4643fd7412ca2fcdb7db0824d009d27c 310 Pfam PF17284 Spermidine synthase tetramerisation domain 13 63 1.1E-9 T 23-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 VMUT_1981 c52c03d1b286c7c318d3b86ed9c2f472 239 Pfam PF01048 Phosphorylase superfamily 14 217 4.2E-35 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 VMUT_1981 c52c03d1b286c7c318d3b86ed9c2f472 239 SUPERFAMILY SSF53167 2 234 1.14E-63 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 VMUT_1981 c52c03d1b286c7c318d3b86ed9c2f472 239 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 60 75 - T 23-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 VMUT_1981 c52c03d1b286c7c318d3b86ed9c2f472 239 Gene3D G3DSA:3.40.50.1580 1 238 5.7E-63 T 23-10-2018 VMUT_0470 9695fcdce315fc0f8070ce13ffecafad 283 SMART SM00316 27 100 4.6E-12 T 23-10-2018 IPR022967 RNA-binding domain, S1 VMUT_0470 9695fcdce315fc0f8070ce13ffecafad 283 Gene3D G3DSA:2.40.50.140 15 101 1.9E-23 T 23-10-2018 VMUT_0470 9695fcdce315fc0f8070ce13ffecafad 283 Pfam PF07541 Eukaryotic translation initiation factor 2 alpha subunit 139 249 2.7E-22 T 23-10-2018 IPR011488 Translation initiation factor 2, alpha subunit GO:0003723|GO:0003743 Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 VMUT_0470 9695fcdce315fc0f8070ce13ffecafad 283 Pfam PF00575 S1 RNA binding domain 26 100 3.7E-7 T 23-10-2018 IPR003029 S1 domain GO:0003676 VMUT_0470 9695fcdce315fc0f8070ce13ffecafad 283 Gene3D G3DSA:3.30.70.1130 192 280 5.3E-24 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 VMUT_0470 9695fcdce315fc0f8070ce13ffecafad 283 SUPERFAMILY SSF116742 102 191 3.66E-20 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 VMUT_0470 9695fcdce315fc0f8070ce13ffecafad 283 SUPERFAMILY SSF110993 193 278 2.22E-21 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 VMUT_0470 9695fcdce315fc0f8070ce13ffecafad 283 Gene3D G3DSA:1.10.150.190 102 191 4.6E-24 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 VMUT_0470 9695fcdce315fc0f8070ce13ffecafad 283 SUPERFAMILY SSF50249 24 106 3.29E-16 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold VMUT_0139 3001dc3770e78c58e8e34f5f525f072d 353 SUPERFAMILY SSF102114 4 289 4.32E-37 T 23-10-2018 VMUT_0139 3001dc3770e78c58e8e34f5f525f072d 353 Pfam PF13353 4Fe-4S single cluster domain 5 107 3.4E-5 T 23-10-2018 VMUT_0139 3001dc3770e78c58e8e34f5f525f072d 353 Gene3D G3DSA:3.20.20.70 2 332 7.7E-41 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_0139 3001dc3770e78c58e8e34f5f525f072d 353 TIGRFAM TIGR04084 rSAM_AF0577: putative peptide-modifying radical SAM enzyme, AF0577 family 5 353 1.3E-171 T 23-10-2018 IPR023819 Peptide-modifying radical SAM enzyme putative, AF0577 VMUT_0139 3001dc3770e78c58e8e34f5f525f072d 353 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 229 297 3.5E-9 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain VMUT_0139 3001dc3770e78c58e8e34f5f525f072d 353 Pfam PF04055 Radical SAM superfamily 7 143 3.3E-12 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_1354 757b83c995adeda00203df94dd963746 357 Gene3D G3DSA:3.40.50.10540 3 347 4.0E-89 T 23-10-2018 IPR023606 CoA-transferase family III domain superfamily VMUT_1354 757b83c995adeda00203df94dd963746 357 Gene3D G3DSA:3.30.1540.10 208 292 4.0E-89 T 23-10-2018 VMUT_1354 757b83c995adeda00203df94dd963746 357 Pfam PF02515 CoA-transferase family III 3 301 3.8E-78 T 23-10-2018 IPR003673 CoA-transferase family III GO:0003824 VMUT_1354 757b83c995adeda00203df94dd963746 357 SUPERFAMILY SSF89796 2 353 6.02E-98 T 23-10-2018 IPR023606 CoA-transferase family III domain superfamily VMUT_0031 a87745f6de2191368fd5b9bec6124eb5 81 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 19 30 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_0031 a87745f6de2191368fd5b9bec6124eb5 81 Gene3D G3DSA:3.30.70.20 10 79 4.5E-14 T 23-10-2018 VMUT_0031 a87745f6de2191368fd5b9bec6124eb5 81 SUPERFAMILY SSF54862 8 75 2.49E-14 T 23-10-2018 VMUT_0031 a87745f6de2191368fd5b9bec6124eb5 81 Pfam PF13187 4Fe-4S dicluster domain 19 70 2.9E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_0031 a87745f6de2191368fd5b9bec6124eb5 81 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 56 67 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_1695 a2b38c5f7bbbd45de507b646d757f2aa 179 Gene3D G3DSA:3.10.290.10 105 178 5.2E-16 T 23-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 VMUT_1695 a2b38c5f7bbbd45de507b646d757f2aa 179 Hamap MF_01306_A 30S ribosomal protein S4 [rpsD]. 1 159 30.175 T 23-10-2018 IPR022802 Ribosomal protein S4, archaeal GO:0006412|GO:0019843 VMUT_1695 a2b38c5f7bbbd45de507b646d757f2aa 179 SMART SM00363 106 169 1.9E-13 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1695 a2b38c5f7bbbd45de507b646d757f2aa 179 SMART SM01390 5 105 3.7E-5 T 23-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 VMUT_1695 a2b38c5f7bbbd45de507b646d757f2aa 179 Pfam PF01479 S4 domain 106 151 1.2E-16 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1695 a2b38c5f7bbbd45de507b646d757f2aa 179 TIGRFAM TIGR01018 uS4_arch: ribosomal protein uS4 1 163 2.2E-56 T 23-10-2018 IPR005710 Ribosomal protein S4/S9, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1695 a2b38c5f7bbbd45de507b646d757f2aa 179 ProSitePatterns PS00632 Ribosomal protein S4 signature. 104 128 - T 23-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1695 a2b38c5f7bbbd45de507b646d757f2aa 179 SUPERFAMILY SSF55174 16 163 7.59E-27 T 23-10-2018 VMUT_1179 9408f4a7900f1b99a87a94cac4f2a2f8 282 SUPERFAMILY SSF53335 16 280 3.8E-35 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_1179 9408f4a7900f1b99a87a94cac4f2a2f8 282 Pfam PF08241 Methyltransferase domain 63 155 4.1E-19 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 VMUT_1179 9408f4a7900f1b99a87a94cac4f2a2f8 282 Gene3D G3DSA:3.40.50.150 7 281 1.0E-38 T 23-10-2018 VMUT_1235 f36a134b7b2b238982c1b883534f6a49 332 Hamap MF_02127 Glucose 1-dehydrogenase [gdh]. 1 330 56.932 T 23-10-2018 IPR026583 Glucose 1-dehydrogenase GO:0005536|GO:0008270|GO:0047936 KEGG: 00030+1.1.1.47 VMUT_1235 f36a134b7b2b238982c1b883534f6a49 332 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 11 118 2.0E-13 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VMUT_1235 f36a134b7b2b238982c1b883534f6a49 332 Gene3D G3DSA:3.40.50.720 126 303 5.3E-101 T 23-10-2018 VMUT_1235 f36a134b7b2b238982c1b883534f6a49 332 SUPERFAMILY SSF50129 3 173 3.96E-36 T 23-10-2018 IPR011032 GroES-like superfamily VMUT_1235 f36a134b7b2b238982c1b883534f6a49 332 Pfam PF16912 Glucose dehydrogenase C-terminus 124 329 3.0E-68 T 23-10-2018 IPR031640 Glucose dehydrogenase, C-terminal KEGG: 00030+1.1.1.47 VMUT_1235 f36a134b7b2b238982c1b883534f6a49 332 SUPERFAMILY SSF51735 124 290 1.39E-19 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1235 f36a134b7b2b238982c1b883534f6a49 332 Gene3D G3DSA:3.90.180.10 2 327 5.3E-101 T 23-10-2018 VMUT_0493 c7b9937d1867cb4f0a5858676160c009 634 Gene3D G3DSA:3.50.50.90 9 630 1.7E-241 T 23-10-2018 VMUT_0493 c7b9937d1867cb4f0a5858676160c009 634 SUPERFAMILY SSF56425 239 378 5.23E-43 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 VMUT_0493 c7b9937d1867cb4f0a5858676160c009 634 PIRSF PIRSF000171 1 633 6.1E-232 T 23-10-2018 VMUT_0493 c7b9937d1867cb4f0a5858676160c009 634 SUPERFAMILY SSF51905 5 472 5.46E-62 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0493 c7b9937d1867cb4f0a5858676160c009 634 SUPERFAMILY SSF46977 504 632 3.79E-41 T 23-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VMUT_0493 c7b9937d1867cb4f0a5858676160c009 634 Gene3D G3DSA:3.90.700.10 264 389 1.7E-241 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 VMUT_0493 c7b9937d1867cb4f0a5858676160c009 634 TIGRFAM TIGR02061 aprA: adenylylsulfate reductase, alpha subunit 10 631 2.7E-255 T 23-10-2018 IPR011803 Adenylylsulphate reductase, alpha subunit KEGG: 00920+1.8.99.2|MetaCyc: PWY-5278|MetaCyc: PWY-5279 VMUT_0493 c7b9937d1867cb4f0a5858676160c009 634 Pfam PF00890 FAD binding domain 10 246 2.3E-13 T 23-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 VMUT_0493 c7b9937d1867cb4f0a5858676160c009 634 Pfam PF02910 Fumarate reductase flavoprotein C-term 530 628 8.8E-7 T 23-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VMUT_2275 427462cd6aa8d2f09e9f08356ce3425f 524 Pfam PF13520 Amino acid permease 14 463 2.1E-32 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_2275 427462cd6aa8d2f09e9f08356ce3425f 524 Gene3D G3DSA:1.20.1740.10 8 460 3.0E-60 T 23-10-2018 VMUT_2275 427462cd6aa8d2f09e9f08356ce3425f 524 PIRSF PIRSF006060 1 523 1.5E-62 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_1701 f535f4a1dfb9613e063921e9104de64b 121 Gene3D G3DSA:3.40.50.300 1 110 3.0E-19 T 23-10-2018 VMUT_1701 f535f4a1dfb9613e063921e9104de64b 121 SUPERFAMILY SSF52540 3 97 8.65E-14 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1096 b346a3b4e1b9dab0db42f75f82d0b46a 368 Pfam PF00534 Glycosyl transferases group 1 188 347 1.5E-20 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 VMUT_1096 b346a3b4e1b9dab0db42f75f82d0b46a 368 Pfam PF13439 Glycosyltransferase Family 4 14 184 3.1E-21 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 VMUT_1096 b346a3b4e1b9dab0db42f75f82d0b46a 368 SUPERFAMILY SSF53756 1 367 4.13E-64 T 23-10-2018 VMUT_1096 b346a3b4e1b9dab0db42f75f82d0b46a 368 Gene3D G3DSA:3.40.50.2000 201 357 3.3E-26 T 23-10-2018 VMUT_1096 b346a3b4e1b9dab0db42f75f82d0b46a 368 Gene3D G3DSA:3.40.50.2000 1 200 1.7E-30 T 23-10-2018 VMUT_1827 139fb39df5d166e4f946222360e74aba 567 Gene3D G3DSA:3.80.30.20 191 453 1.9E-16 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe VMUT_1827 139fb39df5d166e4f946222360e74aba 567 SMART SM00729 187 432 7.1E-19 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VMUT_1827 139fb39df5d166e4f946222360e74aba 567 SUPERFAMILY SSF102114 184 437 3.14E-18 T 23-10-2018 VMUT_1827 139fb39df5d166e4f946222360e74aba 567 SUPERFAMILY SSF47781 513 558 5.78E-6 T 23-10-2018 IPR010994 RuvA domain 2-like VMUT_1827 139fb39df5d166e4f946222360e74aba 567 Pfam PF04055 Radical SAM superfamily 203 390 2.7E-12 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_0647 6aee6b3db1b7d0bc6aebc61b66f34ec4 142 SUPERFAMILY SSF46785 6 130 9.09E-30 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0647 6aee6b3db1b7d0bc6aebc61b66f34ec4 142 Pfam PF01475 Ferric uptake regulator family 14 122 1.2E-24 T 23-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 VMUT_0647 6aee6b3db1b7d0bc6aebc61b66f34ec4 142 Gene3D G3DSA:1.10.10.10 1 82 3.1E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_2149 3a30bca48cd5dc36c45023800cbecfdc 520 PIRSF PIRSF006060 1 520 1.5E-25 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_2149 3a30bca48cd5dc36c45023800cbecfdc 520 PRINTS PR01692 Lipocalin-1 interacting membrane receptor signature 173 194 6.0E-7 T 23-10-2018 IPR008075 Lipocalin-interacting membrane receptor VMUT_2149 3a30bca48cd5dc36c45023800cbecfdc 520 PRINTS PR01692 Lipocalin-1 interacting membrane receptor signature 52 74 6.0E-7 T 23-10-2018 IPR008075 Lipocalin-interacting membrane receptor VMUT_2149 3a30bca48cd5dc36c45023800cbecfdc 520 PRINTS PR01692 Lipocalin-1 interacting membrane receptor signature 395 416 6.0E-7 T 23-10-2018 IPR008075 Lipocalin-interacting membrane receptor VMUT_2149 3a30bca48cd5dc36c45023800cbecfdc 520 PRINTS PR01692 Lipocalin-1 interacting membrane receptor signature 320 341 6.0E-7 T 23-10-2018 IPR008075 Lipocalin-interacting membrane receptor VMUT_2149 3a30bca48cd5dc36c45023800cbecfdc 520 Pfam PF13520 Amino acid permease 24 495 6.8E-10 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_2149 3a30bca48cd5dc36c45023800cbecfdc 520 Gene3D G3DSA:1.20.1740.10 16 517 2.1E-10 T 23-10-2018 VMUT_2088 899ac83c5619c922b7d61b7b5f2e980b 159 Gene3D G3DSA:1.20.120.330 31 157 1.9E-37 T 23-10-2018 VMUT_2088 899ac83c5619c922b7d61b7b5f2e980b 159 Pfam PF05942 Archaeal PaREP1/PaREP8 family 36 149 1.2E-31 T 23-10-2018 IPR010268 Archaeal PaREP1 VMUT_0561 8b314713ffce7afcc2113321ef95955c 246 Pfam PF03437 BtpA family 1 241 9.4E-73 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family VMUT_0561 8b314713ffce7afcc2113321ef95955c 246 ProDom PD011184 BTPA I PHOTOSYSTEM BIOGENESIS ASSEMBLY SGCQ TRIPHOSPHATASE NUCLEOSIDE PAE3553 ENZYME 18 187 6.0E-47 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family VMUT_0561 8b314713ffce7afcc2113321ef95955c 246 SUPERFAMILY SSF51366 20 239 2.83E-20 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 VMUT_0561 8b314713ffce7afcc2113321ef95955c 246 TIGRFAM TIGR00259 thylakoid_BtpA: membrane complex biogenesis protein, BtpA family 1 241 7.1E-66 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family VMUT_0561 8b314713ffce7afcc2113321ef95955c 246 PIRSF PIRSF005956 1 246 2.7E-82 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family VMUT_1540 1c2fcbf1beaee2a05116047fca9bda91 269 Pfam PF00696 Amino acid kinase family 1 248 5.2E-38 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 VMUT_1540 1c2fcbf1beaee2a05116047fca9bda91 269 Gene3D G3DSA:3.40.1160.10 2 267 6.7E-63 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily VMUT_1540 1c2fcbf1beaee2a05116047fca9bda91 269 Hamap MF_02082 [LysW]-aminoadipate/[LysW]-glutamate kinase [lysZ]. 2 267 50.852 T 23-10-2018 IPR037529 [LysW]-aminoadipate/[LysW]-glutamate kinase GO:0016301 VMUT_1540 1c2fcbf1beaee2a05116047fca9bda91 269 TIGRFAM TIGR00761 argB: acetylglutamate kinase 3 246 2.4E-56 T 23-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 VMUT_1540 1c2fcbf1beaee2a05116047fca9bda91 269 SUPERFAMILY SSF53633 1 268 1.23E-54 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily VMUT_1540 1c2fcbf1beaee2a05116047fca9bda91 269 PIRSF PIRSF000728 1 268 1.1E-64 T 23-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 VMUT_0450 89e5d021263562e1f554d938a0033838 137 SUPERFAMILY SSF55282 6 124 3.53E-26 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0450 89e5d021263562e1f554d938a0033838 137 Pfam PF01877 RNA binding 6 121 5.9E-27 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 VMUT_0450 89e5d021263562e1f554d938a0033838 137 Gene3D G3DSA:3.30.1440.10 1 136 1.2E-32 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1352 77fabfc9df4d97a568ac3a8ff29dc15e 401 Gene3D G3DSA:3.20.20.10 28 259 2.9E-116 T 23-10-2018 IPR029066 PLP-binding barrel VMUT_1352 77fabfc9df4d97a568ac3a8ff29dc15e 401 Gene3D G3DSA:2.40.37.10 9 386 2.9E-116 T 23-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 VMUT_1352 77fabfc9df4d97a568ac3a8ff29dc15e 401 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 9 396 35.736 T 23-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VMUT_1352 77fabfc9df4d97a568ac3a8ff29dc15e 401 SUPERFAMILY SSF51419 20 266 1.03E-58 T 23-10-2018 IPR029066 PLP-binding barrel VMUT_1352 77fabfc9df4d97a568ac3a8ff29dc15e 401 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 29 264 3.9E-35 T 23-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 VMUT_1352 77fabfc9df4d97a568ac3a8ff29dc15e 401 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 68 80 1.8E-19 T 23-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 VMUT_1352 77fabfc9df4d97a568ac3a8ff29dc15e 401 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 48 66 1.8E-19 T 23-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 VMUT_1352 77fabfc9df4d97a568ac3a8ff29dc15e 401 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 254 273 1.8E-19 T 23-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 VMUT_1352 77fabfc9df4d97a568ac3a8ff29dc15e 401 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 353 366 1.8E-19 T 23-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 VMUT_1352 77fabfc9df4d97a568ac3a8ff29dc15e 401 SUPERFAMILY SSF50621 248 398 5.65E-51 T 23-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 VMUT_1352 77fabfc9df4d97a568ac3a8ff29dc15e 401 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 215 228 - T 23-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site VMUT_1352 77fabfc9df4d97a568ac3a8ff29dc15e 401 PRINTS PR01181 Diaminopimelate decarboxylase signature 282 300 2.1E-19 T 23-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VMUT_1352 77fabfc9df4d97a568ac3a8ff29dc15e 401 PRINTS PR01181 Diaminopimelate decarboxylase signature 363 385 2.1E-19 T 23-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VMUT_1352 77fabfc9df4d97a568ac3a8ff29dc15e 401 PRINTS PR01181 Diaminopimelate decarboxylase signature 151 160 2.1E-19 T 23-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VMUT_1352 77fabfc9df4d97a568ac3a8ff29dc15e 401 PRINTS PR01181 Diaminopimelate decarboxylase signature 66 83 2.1E-19 T 23-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VMUT_1352 77fabfc9df4d97a568ac3a8ff29dc15e 401 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 8 394 4.2E-103 T 23-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VMUT_1352 77fabfc9df4d97a568ac3a8ff29dc15e 401 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 265 353 9.2E-25 T 23-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 VMUT_2147 b9924cb12eff6415967f0677866d0aa5 439 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 322 425 4.4E-15 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 VMUT_2147 b9924cb12eff6415967f0677866d0aa5 439 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 278 1.6E-50 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VMUT_2147 b9924cb12eff6415967f0677866d0aa5 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 226 242 1.3E-25 T 23-10-2018 VMUT_2147 b9924cb12eff6415967f0677866d0aa5 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 1.3E-25 T 23-10-2018 VMUT_2147 b9924cb12eff6415967f0677866d0aa5 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.3E-25 T 23-10-2018 VMUT_2147 b9924cb12eff6415967f0677866d0aa5 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 1.3E-25 T 23-10-2018 VMUT_2147 b9924cb12eff6415967f0677866d0aa5 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 1.3E-25 T 23-10-2018 VMUT_2147 b9924cb12eff6415967f0677866d0aa5 439 Gene3D G3DSA:3.50.50.60 2 331 3.9E-134 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_2147 b9924cb12eff6415967f0677866d0aa5 439 SUPERFAMILY SSF55424 314 436 2.75E-27 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 VMUT_2147 b9924cb12eff6415967f0677866d0aa5 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 378 393 1.2E-20 T 23-10-2018 VMUT_2147 b9924cb12eff6415967f0677866d0aa5 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 1.2E-20 T 23-10-2018 VMUT_2147 b9924cb12eff6415967f0677866d0aa5 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 1.2E-20 T 23-10-2018 VMUT_2147 b9924cb12eff6415967f0677866d0aa5 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 227 241 1.2E-20 T 23-10-2018 VMUT_2147 b9924cb12eff6415967f0677866d0aa5 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 142 167 1.2E-20 T 23-10-2018 VMUT_2147 b9924cb12eff6415967f0677866d0aa5 439 Gene3D G3DSA:3.50.50.60 107 433 3.9E-134 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_2147 b9924cb12eff6415967f0677866d0aa5 439 SUPERFAMILY SSF51905 1 337 5.41E-46 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0469 fc4d15be4957265a6e9c9ee9bc518e24 71 Pfam PF01667 Ribosomal protein S27 16 62 4.0E-21 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0469 fc4d15be4957265a6e9c9ee9bc518e24 71 SUPERFAMILY SSF57829 16 66 7.14E-17 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 VMUT_0469 fc4d15be4957265a6e9c9ee9bc518e24 71 ProSitePatterns PS01168 Ribosomal protein S27e signature. 24 56 - T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0469 fc4d15be4957265a6e9c9ee9bc518e24 71 Gene3D G3DSA:2.20.25.100 17 71 2.1E-20 T 23-10-2018 IPR023407 Ribosomal protein S27e, zinc-binding domain superfamily VMUT_0469 fc4d15be4957265a6e9c9ee9bc518e24 71 Hamap MF_00371 30S ribosomal protein S27e [rps27e]. 10 70 20.71 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1656 58ac4366a899d04a70222d5ea4577db8 229 Gene3D G3DSA:1.10.150.240 35 97 1.8E-48 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 VMUT_1656 58ac4366a899d04a70222d5ea4577db8 229 Pfam PF13419 Haloacid dehalogenase-like hydrolase 23 197 9.0E-40 T 23-10-2018 VMUT_1656 58ac4366a899d04a70222d5ea4577db8 229 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 77 197 4.9E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VMUT_1656 58ac4366a899d04a70222d5ea4577db8 229 Gene3D G3DSA:3.40.50.1000 23 199 1.8E-48 T 23-10-2018 IPR023214 HAD superfamily VMUT_1656 58ac4366a899d04a70222d5ea4577db8 229 SUPERFAMILY SSF56784 17 204 9.63E-56 T 23-10-2018 IPR036412 HAD-like superfamily VMUT_1656 58ac4366a899d04a70222d5ea4577db8 229 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 101 192 2.5E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VMUT_1168 956c060dc1379400472e3a4188d284a4 463 Pfam PF00202 Aminotransferase class-III 46 455 1.3E-107 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VMUT_1168 956c060dc1379400472e3a4188d284a4 463 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 270 307 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VMUT_1168 956c060dc1379400472e3a4188d284a4 463 SUPERFAMILY SSF53383 38 458 4.59E-126 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VMUT_1168 956c060dc1379400472e3a4188d284a4 463 PIRSF PIRSF000521 148 458 1.6E-41 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VMUT_1168 956c060dc1379400472e3a4188d284a4 463 PIRSF PIRSF000521 2 156 3.0E-8 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VMUT_1168 956c060dc1379400472e3a4188d284a4 463 Gene3D G3DSA:3.90.1150.10 39 451 1.5E-142 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VMUT_1168 956c060dc1379400472e3a4188d284a4 463 Gene3D G3DSA:3.40.640.10 84 353 1.5E-142 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VMUT_1627 9061cfe83b65cf3dcd1abb35d506b431 63 Pfam PF11520 Chromatin protein Cren7 13 53 4.3E-13 T 23-10-2018 IPR020906 Double-stranded DNA-binding Cren7 GO:0003690|GO:0005737 VMUT_1627 9061cfe83b65cf3dcd1abb35d506b431 63 Gene3D G3DSA:2.30.30.610 10 55 1.4E-9 T 23-10-2018 IPR038647 Cren7 superfamily VMUT_1627 9061cfe83b65cf3dcd1abb35d506b431 63 Hamap MF_01387 Chromatin protein Cren7 [creN7]. 4 57 15.869 T 23-10-2018 IPR020906 Double-stranded DNA-binding Cren7 GO:0003690|GO:0005737 VMUT_1228 7f0150e678f5c6fbbe62a98778c94135 393 SUPERFAMILY SSF53901 13 234 1.79E-30 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_1228 7f0150e678f5c6fbbe62a98778c94135 393 Gene3D G3DSA:3.40.47.10 5 393 7.2E-95 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_1228 7f0150e678f5c6fbbe62a98778c94135 393 SUPERFAMILY SSF53901 255 371 2.88E-22 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_1228 7f0150e678f5c6fbbe62a98778c94135 393 Pfam PF00108 Thiolase, N-terminal domain 28 230 3.2E-8 T 23-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 VMUT_1228 7f0150e678f5c6fbbe62a98778c94135 393 PIRSF PIRSF000429 6 393 9.2E-37 T 23-10-2018 IPR002155 Thiolase GO:0016747 VMUT_1339 97eacb29eb9b2f4c047211f2d95d6b4c 240 SUPERFAMILY SSF52540 4 228 1.17E-71 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1339 97eacb29eb9b2f4c047211f2d95d6b4c 240 Pfam PF00005 ABC transporter 19 167 1.4E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_1339 97eacb29eb9b2f4c047211f2d95d6b4c 240 Gene3D G3DSA:3.40.50.300 1 238 3.0E-66 T 23-10-2018 VMUT_1339 97eacb29eb9b2f4c047211f2d95d6b4c 240 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VMUT_1339 97eacb29eb9b2f4c047211f2d95d6b4c 240 SMART SM00382 28 231 1.3E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0996 e5f733d80058f0effa0c6b2c74e8aad9 383 Gene3D G3DSA:3.40.50.300 159 261 3.0E-8 T 23-10-2018 VMUT_0996 e5f733d80058f0effa0c6b2c74e8aad9 383 Gene3D G3DSA:3.40.50.300 2 120 1.2E-6 T 23-10-2018 VMUT_0996 e5f733d80058f0effa0c6b2c74e8aad9 383 SUPERFAMILY SSF52540 6 260 4.08E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0996 e5f733d80058f0effa0c6b2c74e8aad9 383 Pfam PF01935 Domain of unknown function DUF87 6 178 1.6E-5 T 23-10-2018 IPR002789 Helicase HerA, central domain VMUT_2052 fe1b3207bb8d09329cf95f02b5839fac 315 SUPERFAMILY SSF51430 1 305 1.44E-96 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VMUT_2052 fe1b3207bb8d09329cf95f02b5839fac 315 Pfam PF00248 Aldo/keto reductase family 15 304 6.6E-72 T 23-10-2018 IPR023210 NADP-dependent oxidoreductase domain VMUT_2052 fe1b3207bb8d09329cf95f02b5839fac 315 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 134 151 - T 23-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 VMUT_2052 fe1b3207bb8d09329cf95f02b5839fac 315 PRINTS PR00069 Aldo-keto reductase signature 101 119 1.7E-12 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VMUT_2052 fe1b3207bb8d09329cf95f02b5839fac 315 PRINTS PR00069 Aldo-keto reductase signature 43 67 1.7E-12 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VMUT_2052 fe1b3207bb8d09329cf95f02b5839fac 315 PRINTS PR00069 Aldo-keto reductase signature 171 200 1.7E-12 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VMUT_2052 fe1b3207bb8d09329cf95f02b5839fac 315 PRINTS PR00069 Aldo-keto reductase signature 134 151 1.7E-12 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VMUT_2052 fe1b3207bb8d09329cf95f02b5839fac 315 Gene3D G3DSA:3.20.20.100 1 313 1.9E-98 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VMUT_1726 9ec2b704222c9345b7f6c2651062aa73 348 Gene3D G3DSA:3.40.800.20 3 346 1.0E-106 T 23-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VMUT_1726 9ec2b704222c9345b7f6c2651062aa73 348 Pfam PF00850 Histone deacetylase domain 19 306 4.8E-84 T 23-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VMUT_1726 9ec2b704222c9345b7f6c2651062aa73 348 SUPERFAMILY SSF52768 3 346 6.71E-102 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily VMUT_1726 9ec2b704222c9345b7f6c2651062aa73 348 PRINTS PR01270 Histone deacetylase superfamily signature 154 169 1.1E-11 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VMUT_1726 9ec2b704222c9345b7f6c2651062aa73 348 PRINTS PR01270 Histone deacetylase superfamily signature 121 144 1.1E-11 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VMUT_1726 9ec2b704222c9345b7f6c2651062aa73 348 PRINTS PR01270 Histone deacetylase superfamily signature 240 250 1.1E-11 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VMUT_1541 1b216f6cc9c9d67f83d3162c78c9830e 398 Gene3D G3DSA:3.40.640.10 67 285 1.9E-105 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VMUT_1541 1b216f6cc9c9d67f83d3162c78c9830e 398 Pfam PF00155 Aminotransferase class I and II 32 372 2.6E-56 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VMUT_1541 1b216f6cc9c9d67f83d3162c78c9830e 398 Gene3D G3DSA:3.90.1150.10 25 385 1.9E-105 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VMUT_1541 1b216f6cc9c9d67f83d3162c78c9830e 398 SUPERFAMILY SSF53383 3 394 2.66E-104 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VMUT_1233 1cdc72df0d66c2b9d6509ae42b5bf690 333 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 129 2.7E-23 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VMUT_1233 1cdc72df0d66c2b9d6509ae42b5bf690 333 SMART SM00829 10 331 1.2E-13 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VMUT_1233 1cdc72df0d66c2b9d6509ae42b5bf690 333 SUPERFAMILY SSF50129 1 167 6.39E-50 T 23-10-2018 IPR011032 GroES-like superfamily VMUT_1233 1cdc72df0d66c2b9d6509ae42b5bf690 333 Pfam PF00107 Zinc-binding dehydrogenase 171 291 2.0E-26 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 VMUT_1233 1cdc72df0d66c2b9d6509ae42b5bf690 333 SUPERFAMILY SSF51735 133 304 1.38E-39 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1233 1cdc72df0d66c2b9d6509ae42b5bf690 333 Gene3D G3DSA:3.90.180.10 1 333 2.3E-98 T 23-10-2018 VMUT_0298 9ab6a6ee86c4ecc87649d7e141bbc6fc 275 PRINTS PR00685 Transcription initiation factor IIB signature 228 244 3.1E-5 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 VMUT_0298 9ab6a6ee86c4ecc87649d7e141bbc6fc 275 PRINTS PR00685 Transcription initiation factor IIB signature 260 274 3.1E-5 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 VMUT_0298 9ab6a6ee86c4ecc87649d7e141bbc6fc 275 PRINTS PR00685 Transcription initiation factor IIB signature 13 33 3.1E-5 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 VMUT_0298 9ab6a6ee86c4ecc87649d7e141bbc6fc 275 Gene3D G3DSA:2.20.25.10 1 35 1.8E-5 T 23-10-2018 VMUT_0298 9ab6a6ee86c4ecc87649d7e141bbc6fc 275 SUPERFAMILY SSF57783 1 30 7.65E-7 T 23-10-2018 VMUT_0298 9ab6a6ee86c4ecc87649d7e141bbc6fc 275 Pfam PF08271 TFIIB zinc-binding 1 28 8.6E-8 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type VMUT_0298 9ab6a6ee86c4ecc87649d7e141bbc6fc 275 Gene3D G3DSA:1.10.472.10 197 275 1.6E-9 T 23-10-2018 VMUT_0298 9ab6a6ee86c4ecc87649d7e141bbc6fc 275 Gene3D G3DSA:1.10.472.10 85 182 1.7E-5 T 23-10-2018 VMUT_0298 9ab6a6ee86c4ecc87649d7e141bbc6fc 275 SUPERFAMILY SSF47954 220 274 1.36E-8 T 23-10-2018 IPR036915 Cyclin-like superfamily VMUT_0298 9ab6a6ee86c4ecc87649d7e141bbc6fc 275 SUPERFAMILY SSF47954 93 163 1.28E-5 T 23-10-2018 IPR036915 Cyclin-like superfamily VMUT_2124 8f6f3c9775474352f6b11464ea7c55e6 190 TIGRFAM TIGR03653 uL6_arch: ribosomal protein uL6 9 185 1.8E-60 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 VMUT_2124 8f6f3c9775474352f6b11464ea7c55e6 190 Pfam PF00347 Ribosomal protein L6 97 161 1.7E-7 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_2124 8f6f3c9775474352f6b11464ea7c55e6 190 Pfam PF00347 Ribosomal protein L6 13 85 6.0E-10 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_2124 8f6f3c9775474352f6b11464ea7c55e6 190 Hamap MF_01365_A 50S ribosomal protein L6 [rplF]. 2 187 34.715 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 VMUT_2124 8f6f3c9775474352f6b11464ea7c55e6 190 SUPERFAMILY SSF56053 9 85 2.88E-19 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_2124 8f6f3c9775474352f6b11464ea7c55e6 190 PIRSF PIRSF002162 3 169 1.2E-37 T 23-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_2124 8f6f3c9775474352f6b11464ea7c55e6 190 Gene3D G3DSA:3.90.930.12 86 189 4.0E-23 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_2124 8f6f3c9775474352f6b11464ea7c55e6 190 Gene3D G3DSA:3.90.930.12 3 85 2.9E-24 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_2124 8f6f3c9775474352f6b11464ea7c55e6 190 SUPERFAMILY SSF56053 86 163 2.78E-23 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0986 e885251399fde1856321cc3c736033c1 219 SUPERFAMILY SSF52540 1 195 6.59E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0986 e885251399fde1856321cc3c736033c1 219 Gene3D G3DSA:3.40.50.300 1 215 3.7E-24 T 23-10-2018 VMUT_0986 e885251399fde1856321cc3c736033c1 219 Pfam PF06745 KaiC 2 194 4.3E-16 T 23-10-2018 IPR014774 KaiC-like domain VMUT_0009 c0b9f728e57ba421c1423dd07e75a4bc 444 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 13 427 6.6E-35 T 23-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 VMUT_0009 c0b9f728e57ba421c1423dd07e75a4bc 444 PIRSF PIRSF002744 2 442 1.6E-102 T 23-10-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 VMUT_0009 c0b9f728e57ba421c1423dd07e75a4bc 444 Gene3D G3DSA:1.10.4160.10 10 419 5.1E-33 T 23-10-2018 IPR038271 Purine-cytosine permease superfamily VMUT_1240 55bbb57edd29f4c0c69774ffe41fc336 473 Gene3D G3DSA:3.40.605.10 6 467 5.3E-164 T 23-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VMUT_1240 55bbb57edd29f4c0c69774ffe41fc336 473 Gene3D G3DSA:3.40.309.10 241 440 5.3E-164 T 23-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VMUT_1240 55bbb57edd29f4c0c69774ffe41fc336 473 SUPERFAMILY SSF53720 4 472 3.8E-155 T 23-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VMUT_1240 55bbb57edd29f4c0c69774ffe41fc336 473 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 265 276 - T 23-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 VMUT_1240 55bbb57edd29f4c0c69774ffe41fc336 473 Pfam PF00171 Aldehyde dehydrogenase family 6 468 5.3E-170 T 23-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VMUT_1240 55bbb57edd29f4c0c69774ffe41fc336 473 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 237 244 - T 23-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 VMUT_1674 37ac4cdf7053350f14a418eff2c5d6a7 229 SMART SM00849 11 188 5.2E-10 T 23-10-2018 IPR001279 Metallo-beta-lactamase VMUT_1674 37ac4cdf7053350f14a418eff2c5d6a7 229 SUPERFAMILY SSF56281 7 225 1.31E-37 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_1674 37ac4cdf7053350f14a418eff2c5d6a7 229 Gene3D G3DSA:3.60.15.10 5 226 9.6E-71 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_1674 37ac4cdf7053350f14a418eff2c5d6a7 229 Pfam PF12706 Beta-lactamase superfamily domain 23 189 3.8E-26 T 23-10-2018 IPR001279 Metallo-beta-lactamase VMUT_1674 37ac4cdf7053350f14a418eff2c5d6a7 229 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 5 226 38.718 T 23-10-2018 IPR022877 Protein of unknown funcion UPF0173 VMUT_0696 8b86f0c43e4762e333c3ddbba49eb1e5 548 SUPERFAMILY SSF52540 3 271 2.34E-115 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0696 8b86f0c43e4762e333c3ddbba49eb1e5 548 TIGRFAM TIGR00337 PyrG: CTP synthase 2 528 9.8E-227 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 VMUT_0696 8b86f0c43e4762e333c3ddbba49eb1e5 548 Pfam PF06418 CTP synthase N-terminus 4 267 9.2E-121 T 23-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 VMUT_0696 8b86f0c43e4762e333c3ddbba49eb1e5 548 Hamap MF_01227 CTP synthase [pyrG]. 3 533 49.59 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 VMUT_0696 8b86f0c43e4762e333c3ddbba49eb1e5 548 Gene3D G3DSA:3.40.50.300 1 285 6.3E-130 T 23-10-2018 VMUT_0696 8b86f0c43e4762e333c3ddbba49eb1e5 548 Gene3D G3DSA:3.40.50.880 286 540 1.0E-101 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like VMUT_0696 8b86f0c43e4762e333c3ddbba49eb1e5 548 Pfam PF00117 Glutamine amidotransferase class-I 302 527 6.2E-55 T 23-10-2018 IPR017926 Glutamine amidotransferase VMUT_0696 8b86f0c43e4762e333c3ddbba49eb1e5 548 SUPERFAMILY SSF52317 292 533 1.8E-73 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like VMUT_1210 eb60f934921c2e7acd77c61b9053f7a6 398 Pfam PF07687 Peptidase dimerisation domain 188 291 7.0E-12 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain VMUT_1210 eb60f934921c2e7acd77c61b9053f7a6 398 SUPERFAMILY SSF55031 191 298 3.74E-16 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VMUT_1210 eb60f934921c2e7acd77c61b9053f7a6 398 Gene3D G3DSA:3.30.70.360 191 311 1.3E-74 T 23-10-2018 VMUT_1210 eb60f934921c2e7acd77c61b9053f7a6 398 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 118 156 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 VMUT_1210 eb60f934921c2e7acd77c61b9053f7a6 398 SUPERFAMILY SSF53187 4 393 8.29E-55 T 23-10-2018 VMUT_1210 eb60f934921c2e7acd77c61b9053f7a6 398 Pfam PF01546 Peptidase family M20/M25/M40 85 391 3.4E-33 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 VMUT_1210 eb60f934921c2e7acd77c61b9053f7a6 398 Gene3D G3DSA:3.40.630.10 12 382 1.3E-74 T 23-10-2018 VMUT_1210 eb60f934921c2e7acd77c61b9053f7a6 398 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 11 385 5.2E-81 T 23-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase VMUT_0141 d2f103879f280a80570151bb5371c55e 461 Gene3D G3DSA:1.20.1250.20 10 217 7.7E-36 T 23-10-2018 VMUT_0141 d2f103879f280a80570151bb5371c55e 461 SUPERFAMILY SSF103473 9 440 1.7E-60 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_0141 d2f103879f280a80570151bb5371c55e 461 Pfam PF07690 Major Facilitator Superfamily 25 402 4.4E-43 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_0141 d2f103879f280a80570151bb5371c55e 461 Gene3D G3DSA:1.20.1250.20 240 446 7.2E-16 T 23-10-2018 VMUT_1172 373578e923ae885cbcf19ae2dffd485c 537 PIRSF PIRSF006060 1 536 1.4E-23 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_1172 373578e923ae885cbcf19ae2dffd485c 537 Pfam PF13520 Amino acid permease 24 495 3.4E-30 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_1172 373578e923ae885cbcf19ae2dffd485c 537 Gene3D G3DSA:1.20.1740.10 20 532 3.3E-11 T 23-10-2018 VMUT_1198 160dbe272e12c902e460b7dfaab8a4ad 415 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 282 387 1.5E-33 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II VMUT_1198 160dbe272e12c902e460b7dfaab8a4ad 415 SUPERFAMILY SSF52922 273 401 2.22E-36 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VMUT_1198 160dbe272e12c902e460b7dfaab8a4ad 415 Gene3D G3DSA:3.40.50.970 21 270 2.9E-70 T 23-10-2018 VMUT_1198 160dbe272e12c902e460b7dfaab8a4ad 415 Gene3D G3DSA:3.40.50.920 272 415 7.5E-47 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VMUT_1198 160dbe272e12c902e460b7dfaab8a4ad 415 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 34 257 9.8E-51 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 VMUT_1198 160dbe272e12c902e460b7dfaab8a4ad 415 SUPERFAMILY SSF52518 24 269 6.87E-46 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold VMUT_1041 88d0e0944184e9fc0f380d30bcf24351 313 Pfam PF00535 Glycosyl transferase family 2 20 173 1.2E-26 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VMUT_1041 88d0e0944184e9fc0f380d30bcf24351 313 Gene3D G3DSA:3.90.550.10 2 238 3.9E-42 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1041 88d0e0944184e9fc0f380d30bcf24351 313 SUPERFAMILY SSF53448 19 272 5.42E-43 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_2267 b0cc08a90df2ec20aa091dc99638d6e1 147 PIRSF PIRSF000239 1 134 5.1E-29 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 VMUT_2267 b0cc08a90df2ec20aa091dc99638d6e1 147 Pfam PF00578 AhpC/TSA family 5 125 4.7E-40 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 VMUT_2267 b0cc08a90df2ec20aa091dc99638d6e1 147 SUPERFAMILY SSF52833 1 145 8.86E-50 T 23-10-2018 IPR036249 Thioredoxin-like superfamily VMUT_2267 b0cc08a90df2ec20aa091dc99638d6e1 147 Gene3D G3DSA:3.40.30.10 3 146 3.5E-49 T 23-10-2018 VMUT_1862 96d4bda9e1407581a63d057829535fb7 253 Gene3D G3DSA:3.40.1010.10 1 118 6.4E-35 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 VMUT_1862 96d4bda9e1407581a63d057829535fb7 253 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 216 6.0E-41 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 VMUT_1862 96d4bda9e1407581a63d057829535fb7 253 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 3 236 1.1E-72 T 23-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 VMUT_1862 96d4bda9e1407581a63d057829535fb7 253 Gene3D G3DSA:3.30.950.10 119 250 1.7E-29 T 23-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 VMUT_1862 96d4bda9e1407581a63d057829535fb7 253 SUPERFAMILY SSF53790 1 237 3.27E-62 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 VMUT_1862 96d4bda9e1407581a63d057829535fb7 253 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 83 116 - T 23-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 VMUT_2117 c92351f78e892b2711270cbfe0c3b22c 438 Pfam PF16575 mRNA cleavage and polyadenylation factor CLP1 P-loop 99 277 1.3E-33 T 23-10-2018 IPR032319 Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain VMUT_2117 c92351f78e892b2711270cbfe0c3b22c 438 SUPERFAMILY SSF52540 94 228 8.82E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_2117 c92351f78e892b2711270cbfe0c3b22c 438 Gene3D G3DSA:3.40.50.300 82 283 5.8E-26 T 23-10-2018 VMUT_0449 9f868d2552e00888f64ac8e623088742 192 Pfam PF00827 Ribosomal L15 4 185 9.4E-63 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0449 9f868d2552e00888f64ac8e623088742 192 SUPERFAMILY SSF54189 3 177 2.45E-63 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_0449 9f868d2552e00888f64ac8e623088742 192 SMART SM01384 4 186 8.5E-100 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0449 9f868d2552e00888f64ac8e623088742 192 Gene3D G3DSA:3.40.1120.10 2 192 2.2E-64 T 23-10-2018 IPR024794 Ribosomal protein L15e core domain superfamily GO:0003735|GO:0005840 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1442 9d82e21a2192d5f9bfdb92cf20720af5 144 Pfam PF07843 Protein of unknown function (DUF1634) 10 122 6.2E-28 T 23-10-2018 IPR012861 Protein of unknown function DUF1634 VMUT_0968 9ab61c6620d947b8aafb2733f9d70397 55 Pfam PF11755 Protein of unknown function (DUF3311) 2 45 4.1E-10 T 23-10-2018 IPR021741 Protein of unknown function DUF3311 VMUT_1615 efdfbfe5f637e1cc58d72364f072ffb5 145 Pfam PF05129 Transcription elongation factor Elf1 like 2 77 2.8E-19 T 23-10-2018 IPR007808 Transcription elongation factor 1 VMUT_1615 efdfbfe5f637e1cc58d72364f072ffb5 145 SUPERFAMILY SSF57783 1 81 7.82E-19 T 23-10-2018 VMUT_1109 86ccd2b27732a1665523e2a09a00ee8d 275 SUPERFAMILY SSF52317 55 217 1.12E-5 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like VMUT_2343 0d1bca8b27e3970d30bf3a75495d73a9 103 Pfam PF02662 Methyl-viologen-reducing hydrogenase, delta subunit 1 94 5.6E-25 T 23-10-2018 IPR003813 F420-non-reducing hydrogenase iron-sulfur subunit D GO:0055114 VMUT_0876 c940241f8cd18cf33d18e3cec75dbd2d 178 Gene3D G3DSA:1.10.10.10 69 147 2.6E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_0876 c940241f8cd18cf33d18e3cec75dbd2d 178 SUPERFAMILY SSF46767 72 144 1.2E-20 T 23-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 VMUT_0876 c940241f8cd18cf33d18e3cec75dbd2d 178 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 72 141 4.1E-21 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 VMUT_0876 c940241f8cd18cf33d18e3cec75dbd2d 178 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 111 117 - T 23-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 VMUT_0876 c940241f8cd18cf33d18e3cec75dbd2d 178 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 72 143 2.2E-22 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 VMUT_0820 aacd7123e1cffad3a6620e52355ef6f1 449 PIRSF PIRSF001220 87 429 6.2E-103 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 VMUT_0820 aacd7123e1cffad3a6620e52355ef6f1 449 PRINTS PR00139 Asparaginase/glutaminase family signature 169 187 2.4E-16 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 VMUT_0820 aacd7123e1cffad3a6620e52355ef6f1 449 PRINTS PR00139 Asparaginase/glutaminase family signature 93 104 2.4E-16 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 VMUT_0820 aacd7123e1cffad3a6620e52355ef6f1 449 PRINTS PR00139 Asparaginase/glutaminase family signature 355 373 2.4E-16 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 VMUT_0820 aacd7123e1cffad3a6620e52355ef6f1 449 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 91 430 3.9E-117 T 23-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 VMUT_0820 aacd7123e1cffad3a6620e52355ef6f1 449 Gene3D G3DSA:3.40.50.40 303 439 6.8E-48 T 23-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 VMUT_0820 aacd7123e1cffad3a6620e52355ef6f1 449 Gene3D G3DSA:3.40.50.1170 81 300 3.6E-68 T 23-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 VMUT_0820 aacd7123e1cffad3a6620e52355ef6f1 449 SUPERFAMILY SSF141300 3 69 7.98E-17 T 23-10-2018 IPR037222 GatD, N-terminal VMUT_0820 aacd7123e1cffad3a6620e52355ef6f1 449 TIGRFAM TIGR02153 gatD_arch: glutamyl-tRNA(Gln) amidotransferase, subunit D 27 433 1.9E-162 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 VMUT_0820 aacd7123e1cffad3a6620e52355ef6f1 449 SUPERFAMILY SSF53774 85 435 1.15E-105 T 23-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 VMUT_0820 aacd7123e1cffad3a6620e52355ef6f1 449 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 170 180 - T 23-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 VMUT_0820 aacd7123e1cffad3a6620e52355ef6f1 449 Hamap MF_00586 Glutamyl-tRNA(Gln) amidotransferase subunit D [gatD]. 17 434 44.484 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 VMUT_0820 aacd7123e1cffad3a6620e52355ef6f1 449 SMART SM00870 92 418 7.8E-127 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 VMUT_0820 aacd7123e1cffad3a6620e52355ef6f1 449 PIRSF PIRSF500175 11 438 1.1E-158 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 VMUT_0820 aacd7123e1cffad3a6620e52355ef6f1 449 Gene3D G3DSA:2.30.30.520 2 74 6.1E-19 T 23-10-2018 IPR037222 GatD, N-terminal VMUT_0820 aacd7123e1cffad3a6620e52355ef6f1 449 Pfam PF00710 Asparaginase, N-terminal 92 284 3.1E-56 T 23-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 VMUT_1033 903de31fac5d3918e968a0069dd52886 211 Gene3D G3DSA:3.40.50.300 6 204 8.1E-7 T 23-10-2018 VMUT_1033 903de31fac5d3918e968a0069dd52886 211 SUPERFAMILY SSF52540 5 126 5.33E-9 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1180 5c73a7326daf5a4e23b7748ea9459f98 325 Pfam PF00149 Calcineurin-like phosphoesterase 5 276 1.7E-4 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 VMUT_1180 5c73a7326daf5a4e23b7748ea9459f98 325 SUPERFAMILY SSF56300 6 318 3.64E-51 T 23-10-2018 VMUT_1180 5c73a7326daf5a4e23b7748ea9459f98 325 Gene3D G3DSA:3.60.21.10 89 298 3.5E-13 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like VMUT_1452 d550e80ea10b3167dc6c9b587168b842 640 SUPERFAMILY SSF52540 131 525 8.21E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1452 d550e80ea10b3167dc6c9b587168b842 640 Gene3D G3DSA:3.40.50.300 352 539 5.1E-46 T 23-10-2018 VMUT_1452 d550e80ea10b3167dc6c9b587168b842 640 Gene3D G3DSA:3.40.50.300 121 236 5.4E-18 T 23-10-2018 VMUT_1452 d550e80ea10b3167dc6c9b587168b842 640 Pfam PF01935 Domain of unknown function DUF87 135 393 4.0E-35 T 23-10-2018 IPR002789 Helicase HerA, central domain VMUT_1864 05bbe029ae4af3b3880f6a67a6cf7edf 524 Gene3D G3DSA:3.40.50.150 20 247 6.3E-26 T 23-10-2018 VMUT_1864 05bbe029ae4af3b3880f6a67a6cf7edf 524 SUPERFAMILY SSF53335 19 233 3.41E-28 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_1864 05bbe029ae4af3b3880f6a67a6cf7edf 524 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 53 67 5.7E-6 T 23-10-2018 VMUT_1864 05bbe029ae4af3b3880f6a67a6cf7edf 524 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 116 128 5.7E-6 T 23-10-2018 VMUT_1864 05bbe029ae4af3b3880f6a67a6cf7edf 524 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 156 180 5.7E-6 T 23-10-2018 VMUT_1864 05bbe029ae4af3b3880f6a67a6cf7edf 524 Pfam PF01555 DNA methylase 23 90 4.1E-5 T 23-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 VMUT_1864 05bbe029ae4af3b3880f6a67a6cf7edf 524 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 119 125 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 VMUT_1919 07ef0006b01584d5e64a330ef882fc23 103 SUPERFAMILY SSF88723 1 98 3.36E-15 T 23-10-2018 IPR029060 PIN-like domain superfamily VMUT_1006 4edd9e9af2123fc9dfcd027818b62a68 523 Pfam PF00437 Type II/IV secretion system protein 171 383 8.7E-22 T 23-10-2018 IPR001482 Type II/IV secretion system protein VMUT_1006 4edd9e9af2123fc9dfcd027818b62a68 523 Gene3D G3DSA:3.40.50.300 228 485 1.2E-36 T 23-10-2018 VMUT_1006 4edd9e9af2123fc9dfcd027818b62a68 523 SUPERFAMILY SSF52540 99 411 2.87E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0423 6a7aa44b7a918f977f1385626f707eed 191 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 9 183 1.5E-44 T 23-10-2018 IPR001303 Class II aldolase/adducin N-terminal VMUT_0423 6a7aa44b7a918f977f1385626f707eed 191 SMART SM01007 8 184 7.4E-53 T 23-10-2018 IPR001303 Class II aldolase/adducin N-terminal VMUT_0423 6a7aa44b7a918f977f1385626f707eed 191 Gene3D G3DSA:3.40.225.10 1 191 1.6E-53 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VMUT_0423 6a7aa44b7a918f977f1385626f707eed 191 SUPERFAMILY SSF53639 1 185 1.22E-50 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VMUT_0172 a355922d3cfe1ee5ff97511b95523d2f 314 Gene3D G3DSA:3.90.850.10 99 314 1.3E-83 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VMUT_0172 a355922d3cfe1ee5ff97511b95523d2f 314 SUPERFAMILY SSF56529 91 312 7.33E-80 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VMUT_0172 a355922d3cfe1ee5ff97511b95523d2f 314 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 104 311 1.3E-69 T 23-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 VMUT_1773 7ccd553ffa769d3792a89b3c75971a4b 67 Pfam PF11781 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 8 37 1.2E-6 T 23-10-2018 IPR021752 Transcription initiation factor Rrn7, Zinc-finger Reactome: R-HSA-427359|Reactome: R-HSA-427413|Reactome: R-HSA-5250924|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73777|Reactome: R-HSA-73863 VMUT_0826 142c0c46ca8b88f4728e3a0d4b9d7a78 253 Gene3D G3DSA:3.40.50.720 1 246 4.0E-79 T 23-10-2018 VMUT_0826 142c0c46ca8b88f4728e3a0d4b9d7a78 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 244 3.9E-62 T 23-10-2018 VMUT_0826 142c0c46ca8b88f4728e3a0d4b9d7a78 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 4.9E-10 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0826 142c0c46ca8b88f4728e3a0d4b9d7a78 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 4.9E-10 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0826 142c0c46ca8b88f4728e3a0d4b9d7a78 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 4.9E-10 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0826 142c0c46ca8b88f4728e3a0d4b9d7a78 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.2E-43 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0826 142c0c46ca8b88f4728e3a0d4b9d7a78 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 3.2E-43 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0826 142c0c46ca8b88f4728e3a0d4b9d7a78 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 3.2E-43 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0826 142c0c46ca8b88f4728e3a0d4b9d7a78 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 3.2E-43 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0826 142c0c46ca8b88f4728e3a0d4b9d7a78 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 3.2E-43 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0826 142c0c46ca8b88f4728e3a0d4b9d7a78 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 3.2E-43 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0826 142c0c46ca8b88f4728e3a0d4b9d7a78 253 SUPERFAMILY SSF51735 6 245 2.89E-80 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0600 16245569e324950f1575abbe3706ac9b 266 Gene3D G3DSA:1.10.1580.10 165 254 2.4E-13 T 23-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily VMUT_0600 16245569e324950f1575abbe3706ac9b 266 PIRSF PIRSF006230 6 260 2.2E-47 T 23-10-2018 IPR016478 GTPase, MTG1 VMUT_0600 16245569e324950f1575abbe3706ac9b 266 Gene3D G3DSA:3.40.50.300 8 164 3.7E-43 T 23-10-2018 VMUT_0600 16245569e324950f1575abbe3706ac9b 266 Pfam PF01926 50S ribosome-binding GTPase 107 165 1.1E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 VMUT_0600 16245569e324950f1575abbe3706ac9b 266 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 108 128 1.0E-5 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 VMUT_0600 16245569e324950f1575abbe3706ac9b 266 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 154 169 1.0E-5 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 VMUT_0600 16245569e324950f1575abbe3706ac9b 266 SUPERFAMILY SSF52540 7 169 2.58E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0282 365322758b04824aff992242de0d1706 397 SUPERFAMILY SSF48256 19 397 4.19E-131 T 23-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 VMUT_0282 365322758b04824aff992242de0d1706 397 Pfam PF00285 Citrate synthase, C-terminal domain 27 380 5.8E-128 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 VMUT_0282 365322758b04824aff992242de0d1706 397 Gene3D G3DSA:1.10.580.10 38 369 8.0E-130 T 23-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 VMUT_0282 365322758b04824aff992242de0d1706 397 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 27 397 1.3E-141 T 23-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 VMUT_0282 365322758b04824aff992242de0d1706 397 PRINTS PR00143 Citrate synthase signature 350 364 1.3E-42 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 VMUT_0282 365322758b04824aff992242de0d1706 397 PRINTS PR00143 Citrate synthase signature 195 210 1.3E-42 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 VMUT_0282 365322758b04824aff992242de0d1706 397 PRINTS PR00143 Citrate synthase signature 330 346 1.3E-42 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 VMUT_0282 365322758b04824aff992242de0d1706 397 PRINTS PR00143 Citrate synthase signature 270 290 1.3E-42 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 VMUT_0282 365322758b04824aff992242de0d1706 397 PRINTS PR00143 Citrate synthase signature 146 159 1.3E-42 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 VMUT_0282 365322758b04824aff992242de0d1706 397 PRINTS PR00143 Citrate synthase signature 217 245 1.3E-42 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 VMUT_0282 365322758b04824aff992242de0d1706 397 ProSitePatterns PS00480 Citrate synthase signature. 277 289 - T 23-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 VMUT_0282 365322758b04824aff992242de0d1706 397 Gene3D G3DSA:1.10.230.10 243 344 8.0E-130 T 23-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain VMUT_0282 365322758b04824aff992242de0d1706 397 PIRSF PIRSF001369 23 397 3.7E-142 T 23-10-2018 IPR024176 Citrate synthase, bacterial-type VMUT_2109 cbf5cd6d2be8ea5103665a79d17d3cb5 210 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 18 160 1.8E-33 T 23-10-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related VMUT_2109 cbf5cd6d2be8ea5103665a79d17d3cb5 210 SUPERFAMILY SSF50475 6 177 2.07E-43 T 23-10-2018 VMUT_2109 cbf5cd6d2be8ea5103665a79d17d3cb5 210 Gene3D G3DSA:2.30.110.10 1 209 4.2E-59 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 VMUT_0501 bfab29817bf06ac4711730abe20266e8 414 SUPERFAMILY SSF55124 13 150 4.19E-31 T 23-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VMUT_0501 bfab29817bf06ac4711730abe20266e8 414 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 151 368 2.3E-19 T 23-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VMUT_0501 bfab29817bf06ac4711730abe20266e8 414 Gene3D G3DSA:3.30.70.2500 57 148 3.1E-7 T 23-10-2018 VMUT_0501 bfab29817bf06ac4711730abe20266e8 414 SUPERFAMILY SSF56014 151 365 2.75E-30 T 23-10-2018 VMUT_0501 bfab29817bf06ac4711730abe20266e8 414 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 83 140 2.0E-4 T 23-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VMUT_0501 bfab29817bf06ac4711730abe20266e8 414 SUPERFAMILY SSF54862 216 283 1.41E-9 T 23-10-2018 VMUT_0501 bfab29817bf06ac4711730abe20266e8 414 Gene3D G3DSA:3.30.413.10 149 375 1.8E-76 T 23-10-2018 VMUT_0501 bfab29817bf06ac4711730abe20266e8 414 Gene3D G3DSA:3.30.70.20 225 295 1.8E-76 T 23-10-2018 VMUT_0428 8dcb0df10388c15e809739fcf8e11e99 313 Gene3D G3DSA:3.40.50.1370 10 308 2.0E-115 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 VMUT_0428 8dcb0df10388c15e809739fcf8e11e99 313 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 10 312 4.3E-119 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 VMUT_0428 8dcb0df10388c15e809739fcf8e11e99 313 Gene3D G3DSA:3.40.50.1370 141 299 2.0E-115 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 VMUT_0428 8dcb0df10388c15e809739fcf8e11e99 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 127 141 2.0E-29 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 VMUT_0428 8dcb0df10388c15e809739fcf8e11e99 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 291 302 2.0E-29 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 VMUT_0428 8dcb0df10388c15e809739fcf8e11e99 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 87 100 2.0E-29 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 VMUT_0428 8dcb0df10388c15e809739fcf8e11e99 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 229 239 2.0E-29 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 VMUT_0428 8dcb0df10388c15e809739fcf8e11e99 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 54 68 2.0E-29 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 VMUT_0428 8dcb0df10388c15e809739fcf8e11e99 313 SUPERFAMILY SSF53671 7 312 3.93E-103 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 VMUT_0428 8dcb0df10388c15e809739fcf8e11e99 313 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 56 63 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VMUT_0428 8dcb0df10388c15e809739fcf8e11e99 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 274 1.3E-27 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VMUT_0428 8dcb0df10388c15e809739fcf8e11e99 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 56 75 1.3E-27 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VMUT_0428 8dcb0df10388c15e809739fcf8e11e99 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 138 149 1.3E-27 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VMUT_0428 8dcb0df10388c15e809739fcf8e11e99 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 277 300 1.3E-27 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VMUT_0428 8dcb0df10388c15e809739fcf8e11e99 313 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 9 313 76.534 T 23-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 VMUT_0428 8dcb0df10388c15e809739fcf8e11e99 313 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 10 151 9.9E-47 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 VMUT_0428 8dcb0df10388c15e809739fcf8e11e99 313 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 157 310 1.2E-54 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 VMUT_2331 02e155621917c31d4f493ba18090711f 314 Gene3D G3DSA:3.40.50.300 21 186 5.6E-46 T 23-10-2018 VMUT_2331 02e155621917c31d4f493ba18090711f 314 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 40 170 7.2E-64 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 VMUT_2331 02e155621917c31d4f493ba18090711f 314 PIRSF PIRSF002849 1 307 2.2E-126 T 23-10-2018 VMUT_2331 02e155621917c31d4f493ba18090711f 314 SUPERFAMILY SSF52540 7 283 6.93E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_2331 02e155621917c31d4f493ba18090711f 314 Gene3D G3DSA:1.10.8.300 200 302 1.0E-30 T 23-10-2018 VMUT_0877 5eecf39aec56693349c7a13cccba67d9 93 Pfam PF02597 ThiS family 6 93 1.4E-9 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 VMUT_0877 5eecf39aec56693349c7a13cccba67d9 93 Gene3D G3DSA:3.10.20.30 1 93 4.2E-19 T 23-10-2018 IPR012675 Beta-grasp domain superfamily VMUT_0877 5eecf39aec56693349c7a13cccba67d9 93 SUPERFAMILY SSF54285 3 93 7.1E-20 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp VMUT_0386 479505f74951877ba884b8ae7974c48c 150 ProSitePatterns PS00362 Ribosomal protein S15 signature. 98 128 - T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_0386 479505f74951877ba884b8ae7974c48c 150 Gene3D G3DSA:1.10.287.10 83 150 7.9E-29 T 23-10-2018 VMUT_0386 479505f74951877ba884b8ae7974c48c 150 SUPERFAMILY SSF47060 66 142 1.29E-18 T 23-10-2018 IPR009068 S15/NS1, RNA-binding VMUT_0386 479505f74951877ba884b8ae7974c48c 150 Pfam PF00312 Ribosomal protein S15 74 146 1.3E-14 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_0386 479505f74951877ba884b8ae7974c48c 150 Hamap MF_01343_A 30S ribosomal protein S15 [rpsO]. 3 149 34.221 T 23-10-2018 IPR023029 Ribosomal protein S15P Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0386 479505f74951877ba884b8ae7974c48c 150 SMART SM01387 71 149 1.5E-15 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_0386 479505f74951877ba884b8ae7974c48c 150 SMART SM01386 2 60 8.0E-27 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0386 479505f74951877ba884b8ae7974c48c 150 Pfam PF08069 Ribosomal S13/S15 N-terminal domain 5 60 3.8E-24 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0386 479505f74951877ba884b8ae7974c48c 150 Gene3D G3DSA:1.10.8.1030 35 82 1.1E-19 T 23-10-2018 VMUT_1015 6c1dfa770d9c448f915d93a88b5bebc8 328 Gene3D G3DSA:3.40.50.300 81 328 2.6E-50 T 23-10-2018 VMUT_1015 6c1dfa770d9c448f915d93a88b5bebc8 328 PIRSF PIRSF005856 5 328 1.5E-50 T 23-10-2018 IPR016467 DNA recombination and repair protein, RecA-like Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 VMUT_1015 6c1dfa770d9c448f915d93a88b5bebc8 328 Pfam PF08423 Rad51 82 327 4.6E-37 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 VMUT_1015 6c1dfa770d9c448f915d93a88b5bebc8 328 SUPERFAMILY SSF52540 93 327 1.62E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0717 a1033e71982defc3ee7b9c8f9fd4eaa9 43 Pfam PF13660 Domain of unknown function (DUF4147) 10 40 1.5E-6 T 23-10-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 VMUT_0717 a1033e71982defc3ee7b9c8f9fd4eaa9 43 Gene3D G3DSA:3.40.50.10180 9 43 5.6E-6 T 23-10-2018 IPR038614 Glycerate kinase, N-terminal domain superfamily Reactome: R-HSA-70350 VMUT_0717 a1033e71982defc3ee7b9c8f9fd4eaa9 43 SUPERFAMILY SSF82544 10 39 2.09E-5 T 23-10-2018 VMUT_0064 545862e93a20d86b2ec3dcb714802843 297 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 117 196 4.6E-12 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal VMUT_1800 0fd2d47db8b29d16398263d2dd98ab16 126 TIGRFAM TIGR02338 gimC_beta: prefoldin, beta subunit 4 113 2.1E-37 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 VMUT_1800 0fd2d47db8b29d16398263d2dd98ab16 126 Pfam PF01920 Prefoldin subunit 9 112 3.9E-22 T 23-10-2018 IPR002777 Prefoldin beta-like GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 VMUT_1800 0fd2d47db8b29d16398263d2dd98ab16 126 Gene3D G3DSA:1.10.287.370 1 117 5.0E-33 T 23-10-2018 IPR009053 Prefoldin VMUT_1800 0fd2d47db8b29d16398263d2dd98ab16 126 SUPERFAMILY SSF46579 7 111 1.57E-23 T 23-10-2018 VMUT_1800 0fd2d47db8b29d16398263d2dd98ab16 126 Hamap MF_00307 Prefoldin subunit beta [pfdB]. 1 122 46.96 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 VMUT_0806 ab57625bc7fd71cf05272db3486163be 224 Gene3D G3DSA:1.10.10.10 19 108 3.7E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_0806 ab57625bc7fd71cf05272db3486163be 224 SUPERFAMILY SSF46785 25 87 1.1E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0806 ab57625bc7fd71cf05272db3486163be 224 Pfam PF01022 Bacterial regulatory protein, arsR family 35 78 3.3E-9 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VMUT_0429 6704d31385519aa29c0693f8bb97b94d 369 Hamap MF_00132 Type 2 DNA topoisomerase 6 subunit A [top6A]. 2 368 38.813 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 VMUT_0429 6704d31385519aa29c0693f8bb97b94d 369 SUPERFAMILY SSF56726 67 367 2.75E-87 T 23-10-2018 IPR036078 Spo11/DNA topoisomerase VI subunit A superfamily GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 VMUT_0429 6704d31385519aa29c0693f8bb97b94d 369 Gene3D G3DSA:3.40.1360.10 149 367 3.9E-76 T 23-10-2018 VMUT_0429 6704d31385519aa29c0693f8bb97b94d 369 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 116 133 3.7E-30 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 VMUT_0429 6704d31385519aa29c0693f8bb97b94d 369 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 340 363 3.7E-30 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 VMUT_0429 6704d31385519aa29c0693f8bb97b94d 369 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 169 187 3.7E-30 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 VMUT_0429 6704d31385519aa29c0693f8bb97b94d 369 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 34 54 3.7E-30 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 VMUT_0429 6704d31385519aa29c0693f8bb97b94d 369 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 225 245 3.7E-30 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 VMUT_0429 6704d31385519aa29c0693f8bb97b94d 369 Pfam PF04406 Type IIB DNA topoisomerase 68 144 3.5E-21 T 23-10-2018 IPR013049 Spo11/DNA topoisomerase VI, subunit A, N-terminal GO:0003677|GO:0003824|GO:0005524|GO:0005694|GO:0006259 Reactome: R-HSA-912446 VMUT_0429 6704d31385519aa29c0693f8bb97b94d 369 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 122 139 2.2E-35 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 VMUT_0429 6704d31385519aa29c0693f8bb97b94d 369 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 219 240 2.2E-35 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 VMUT_0429 6704d31385519aa29c0693f8bb97b94d 369 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 92 103 2.2E-35 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 VMUT_0429 6704d31385519aa29c0693f8bb97b94d 369 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 140 155 2.2E-35 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 VMUT_0429 6704d31385519aa29c0693f8bb97b94d 369 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 195 212 2.2E-35 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 VMUT_0429 6704d31385519aa29c0693f8bb97b94d 369 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 251 267 2.2E-35 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 VMUT_0429 6704d31385519aa29c0693f8bb97b94d 369 Gene3D G3DSA:1.10.10.10 2 147 1.6E-48 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_0430 4c2af3df816466afc0d3a822d084ba46 323 Pfam PF13394 4Fe-4S single cluster domain 18 97 1.1E-5 T 23-10-2018 VMUT_0430 4c2af3df816466afc0d3a822d084ba46 323 TIGRFAM TIGR02668 moaA_archaeal: probable molybdenum cofactor biosynthesis protein A 2 301 1.4E-101 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 VMUT_0430 4c2af3df816466afc0d3a822d084ba46 323 SUPERFAMILY SSF102114 2 289 1.44E-61 T 23-10-2018 VMUT_0430 4c2af3df816466afc0d3a822d084ba46 323 SMART SM00729 11 209 8.9E-4 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VMUT_0430 4c2af3df816466afc0d3a822d084ba46 323 Pfam PF06463 Molybdenum Cofactor Synthesis C 181 300 1.4E-22 T 23-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VMUT_0430 4c2af3df816466afc0d3a822d084ba46 323 Gene3D G3DSA:3.20.20.70 1 310 1.2E-66 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_0430 4c2af3df816466afc0d3a822d084ba46 323 Pfam PF04055 Radical SAM superfamily 16 173 1.4E-23 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_0430 4c2af3df816466afc0d3a822d084ba46 323 Hamap MF_01225_A GTP 3',8-cyclase [moaA]. 2 302 38.581 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 VMUT_0778 8c679626ae479deb86ad8d48619c94a5 400 Gene3D G3DSA:3.40.640.10 3 395 1.5E-101 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VMUT_0778 8c679626ae479deb86ad8d48619c94a5 400 SUPERFAMILY SSF53383 3 392 1.84E-97 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VMUT_0778 8c679626ae479deb86ad8d48619c94a5 400 Pfam PF00155 Aminotransferase class I and II 63 385 4.1E-51 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VMUT_1979 4e96ccb7366be5615e8ca73e9a0b253e 307 SMART SM00525 270 290 2.7E-4 T 23-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 VMUT_1979 4e96ccb7366be5615e8ca73e9a0b253e 307 SUPERFAMILY SSF48150 132 293 6.41E-23 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 VMUT_1979 4e96ccb7366be5615e8ca73e9a0b253e 307 Gene3D G3DSA:1.10.1670.10 187 301 7.0E-13 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 VMUT_0655 5963d0f4ebbfa0d82aacb386f5f4ca6d 435 Hamap MF_01508 Replication factor C large subunit [rfcL]. 5 411 32.717 T 23-10-2018 IPR023935 Replication factor C, large subunit VMUT_0655 5963d0f4ebbfa0d82aacb386f5f4ca6d 435 Pfam PF08519 Replication factor RFC1 C terminal domain 290 400 1.7E-9 T 23-10-2018 IPR013725 DNA replication factor RFC1, C-terminal GO:0003689|GO:0005524|GO:0005663|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 VMUT_0655 5963d0f4ebbfa0d82aacb386f5f4ca6d 435 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 46 146 5.1E-13 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VMUT_0655 5963d0f4ebbfa0d82aacb386f5f4ca6d 435 SUPERFAMILY SSF48019 232 355 1.38E-6 T 23-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 VMUT_0655 5963d0f4ebbfa0d82aacb386f5f4ca6d 435 SMART SM00382 42 164 8.5E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0655 5963d0f4ebbfa0d82aacb386f5f4ca6d 435 SUPERFAMILY SSF52540 5 223 3.42E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0655 5963d0f4ebbfa0d82aacb386f5f4ca6d 435 Gene3D G3DSA:1.10.8.60 166 228 2.9E-16 T 23-10-2018 VMUT_0655 5963d0f4ebbfa0d82aacb386f5f4ca6d 435 Gene3D G3DSA:3.40.50.300 6 162 5.5E-44 T 23-10-2018 VMUT_1162 61b560ed15afc64f9677f8997dee4495 401 Pfam PF07690 Major Facilitator Superfamily 25 322 5.7E-18 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_1162 61b560ed15afc64f9677f8997dee4495 401 SUPERFAMILY SSF103473 20 390 7.59E-35 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_1162 61b560ed15afc64f9677f8997dee4495 401 Gene3D G3DSA:1.20.1250.20 7 388 3.1E-31 T 23-10-2018 VMUT_1249 fc9f83068ce28508d027dc2fc7cfb3ca 531 Gene3D G3DSA:3.40.50.300 13 253 2.0E-51 T 23-10-2018 VMUT_1249 fc9f83068ce28508d027dc2fc7cfb3ca 531 SMART SM00382 304 501 0.005 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_1249 fc9f83068ce28508d027dc2fc7cfb3ca 531 SMART SM00382 38 227 9.8E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_1249 fc9f83068ce28508d027dc2fc7cfb3ca 531 Pfam PF00005 ABC transporter 295 451 1.8E-20 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_1249 fc9f83068ce28508d027dc2fc7cfb3ca 531 SUPERFAMILY SSF52540 293 503 2.01E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1249 fc9f83068ce28508d027dc2fc7cfb3ca 531 Gene3D G3DSA:3.40.50.300 261 526 2.5E-38 T 23-10-2018 VMUT_1249 fc9f83068ce28508d027dc2fc7cfb3ca 531 SUPERFAMILY SSF52540 13 239 1.84E-52 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1249 fc9f83068ce28508d027dc2fc7cfb3ca 531 Pfam PF00005 ABC transporter 29 180 9.3E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_1301 1ca61b9c6e60c08edb1181808075b548 228 Pfam PF01544 CorA-like Mg2+ transporter protein 125 224 1.7E-11 T 23-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 VMUT_1301 1ca61b9c6e60c08edb1181808075b548 228 Gene3D G3DSA:1.20.58.340 151 228 3.2E-13 T 23-10-2018 VMUT_1301 1ca61b9c6e60c08edb1181808075b548 228 SUPERFAMILY SSF144083 164 226 6.02E-8 T 23-10-2018 VMUT_0135 8f0eb27f58088c6aca2b4fee859cbf33 192 Gene3D G3DSA:3.40.50.300 2 183 1.6E-27 T 23-10-2018 VMUT_0135 8f0eb27f58088c6aca2b4fee859cbf33 192 Pfam PF13238 AAA domain 5 122 2.0E-13 T 23-10-2018 VMUT_0135 8f0eb27f58088c6aca2b4fee859cbf33 192 SUPERFAMILY SSF52540 3 163 2.28E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1985 a577a7c05a766714e64e0196a962cbb3 242 Gene3D G3DSA:3.30.70.3000 23 239 2.7E-29 T 23-10-2018 IPR038469 tRNAHis guanylyltransferase Thg1 superfamily Reactome: R-HSA-6782315 VMUT_1985 a577a7c05a766714e64e0196a962cbb3 242 Pfam PF04446 tRNAHis guanylyltransferase 36 135 3.9E-17 T 23-10-2018 IPR024956 tRNAHis guanylyltransferase catalytic domain GO:0000287|GO:0006400|GO:0008193 Reactome: R-HSA-6782315 VMUT_0638 4bc721c322f1ff1615a9d9c8701fb7e7 393 Gene3D G3DSA:3.40.50.970 12 209 2.6E-73 T 23-10-2018 VMUT_0638 4bc721c322f1ff1615a9d9c8701fb7e7 393 SUPERFAMILY SSF52518 20 270 1.32E-64 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold VMUT_0638 4bc721c322f1ff1615a9d9c8701fb7e7 393 Gene3D G3DSA:3.40.50.920 279 393 5.1E-18 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VMUT_0638 4bc721c322f1ff1615a9d9c8701fb7e7 393 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 289 365 4.0E-16 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II VMUT_0638 4bc721c322f1ff1615a9d9c8701fb7e7 393 SUPERFAMILY SSF52922 281 392 1.57E-22 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VMUT_0638 4bc721c322f1ff1615a9d9c8701fb7e7 393 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 31 259 2.8E-66 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 VMUT_0712 9f2ff612d813a91dbd3cebf9f2da9e29 308 Pfam PF10120 Thiamine-phosphate synthase 140 301 3.8E-43 T 23-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 VMUT_0712 9f2ff612d813a91dbd3cebf9f2da9e29 308 Gene3D G3DSA:3.40.225.10 129 308 6.5E-40 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VMUT_0712 9f2ff612d813a91dbd3cebf9f2da9e29 308 SUPERFAMILY SSF47413 18 71 9.28E-5 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VMUT_0712 9f2ff612d813a91dbd3cebf9f2da9e29 308 SUPERFAMILY SSF53639 135 306 1.92E-39 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VMUT_1884 e12068f615ecfd40205c37cd854b1149 124 Pfam PF07788 PD-(D/E)XK nuclease superfamily 39 112 3.8E-26 T 23-10-2018 IPR012431 PD-(D/E)XK nuclease VMUT_1884 e12068f615ecfd40205c37cd854b1149 124 Pfam PF12644 Protein of unknown function (DUF3782) 1 38 1.0E-12 T 23-10-2018 IPR024271 Protein of unknown function DUF3782 VMUT_2016 12c1d16f2786ab295708dfb5e3d73123 97 SUPERFAMILY SSF88723 2 83 2.66E-11 T 23-10-2018 IPR029060 PIN-like domain superfamily VMUT_2016 12c1d16f2786ab295708dfb5e3d73123 97 Pfam PF01850 PIN domain 21 77 8.5E-6 T 23-10-2018 IPR002716 PIN domain VMUT_2016 12c1d16f2786ab295708dfb5e3d73123 97 Gene3D G3DSA:3.40.50.1010 1 84 2.8E-15 T 23-10-2018 VMUT_0504 e1958729ef54b3bc7e4660992d65e514 111 Gene3D G3DSA:1.10.10.370 48 111 8.6E-28 T 23-10-2018 VMUT_0504 e1958729ef54b3bc7e4660992d65e514 111 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 10 111 4.6E-35 T 23-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE VMUT_0504 e1958729ef54b3bc7e4660992d65e514 111 SUPERFAMILY SSF69721 2 111 9.16E-37 T 23-10-2018 IPR025526 DsrC-like domain superfamily VMUT_0504 e1958729ef54b3bc7e4660992d65e514 111 PIRSF PIRSF006223 9 111 2.1E-31 T 23-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE VMUT_0504 e1958729ef54b3bc7e4660992d65e514 111 Pfam PF04358 DsrC like protein 10 111 1.6E-35 T 23-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE VMUT_0504 e1958729ef54b3bc7e4660992d65e514 111 Gene3D G3DSA:3.30.1420.10 1 47 1.8E-25 T 23-10-2018 VMUT_1992 a341f1d91622cef2ca4568b6da6b30b3 87 SUPERFAMILY SSF81301 8 68 5.72E-8 T 23-10-2018 VMUT_1992 a341f1d91622cef2ca4568b6da6b30b3 87 Gene3D G3DSA:3.30.460.10 8 78 7.8E-6 T 23-10-2018 VMUT_1643 86c45c3b2994093326944309fdf62669 263 Gene3D G3DSA:3.40.50.150 66 259 4.6E-64 T 23-10-2018 VMUT_1643 86c45c3b2994093326944309fdf62669 263 SUPERFAMILY SSF53335 2 253 4.47E-65 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_1643 86c45c3b2994093326944309fdf62669 263 Gene3D G3DSA:3.10.330.20 3 62 1.4E-15 T 23-10-2018 VMUT_1643 86c45c3b2994093326944309fdf62669 263 PIRSF PIRSF017269 1 263 2.0E-80 T 23-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 VMUT_1643 86c45c3b2994093326944309fdf62669 263 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 75 235 1.5E-35 T 23-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 VMUT_1953 42926d1c9bbe8ad6f2bd1416f7cdda0f 486 Gene3D G3DSA:3.30.450.380 1 203 1.1E-59 T 23-10-2018 VMUT_1953 42926d1c9bbe8ad6f2bd1416f7cdda0f 486 Pfam PF00437 Type II/IV secretion system protein 110 361 1.5E-46 T 23-10-2018 IPR001482 Type II/IV secretion system protein VMUT_1953 42926d1c9bbe8ad6f2bd1416f7cdda0f 486 SUPERFAMILY SSF52540 88 396 8.08E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1953 42926d1c9bbe8ad6f2bd1416f7cdda0f 486 Gene3D G3DSA:3.40.50.300 204 483 1.9E-81 T 23-10-2018 VMUT_0864 2be4e03b3ed810e17a14e7a38bcc0309 153 SUPERFAMILY SSF52121 2 142 1.57E-40 T 23-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VMUT_0864 2be4e03b3ed810e17a14e7a38bcc0309 153 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 5 137 3.1E-42 T 23-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VMUT_0864 2be4e03b3ed810e17a14e7a38bcc0309 153 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 1 140 22.054 T 23-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VMUT_0864 2be4e03b3ed810e17a14e7a38bcc0309 153 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 5 136 2.1E-36 T 23-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VMUT_0864 2be4e03b3ed810e17a14e7a38bcc0309 153 Gene3D G3DSA:3.40.50.960 1 143 7.9E-34 T 23-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VMUT_1417 f389f0165ccb2eed75efc57d9df707b7 193 PRINTS PR00097 Anthranilate synthase component II signature 169 182 2.7E-32 T 23-10-2018 VMUT_1417 f389f0165ccb2eed75efc57d9df707b7 193 PRINTS PR00097 Anthranilate synthase component II signature 104 112 2.7E-32 T 23-10-2018 VMUT_1417 f389f0165ccb2eed75efc57d9df707b7 193 PRINTS PR00097 Anthranilate synthase component II signature 49 58 2.7E-32 T 23-10-2018 VMUT_1417 f389f0165ccb2eed75efc57d9df707b7 193 PRINTS PR00097 Anthranilate synthase component II signature 79 90 2.7E-32 T 23-10-2018 VMUT_1417 f389f0165ccb2eed75efc57d9df707b7 193 PRINTS PR00097 Anthranilate synthase component II signature 4 18 2.7E-32 T 23-10-2018 VMUT_1417 f389f0165ccb2eed75efc57d9df707b7 193 PRINTS PR00097 Anthranilate synthase component II signature 125 137 2.7E-32 T 23-10-2018 VMUT_1417 f389f0165ccb2eed75efc57d9df707b7 193 Gene3D G3DSA:3.40.50.880 1 191 7.1E-69 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like VMUT_1417 f389f0165ccb2eed75efc57d9df707b7 193 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 4 191 1.1E-60 T 23-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 VMUT_1417 f389f0165ccb2eed75efc57d9df707b7 193 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 46 60 2.3E-10 T 23-10-2018 VMUT_1417 f389f0165ccb2eed75efc57d9df707b7 193 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 79 95 2.3E-10 T 23-10-2018 VMUT_1417 f389f0165ccb2eed75efc57d9df707b7 193 SUPERFAMILY SSF52317 1 191 7.94E-59 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like VMUT_1417 f389f0165ccb2eed75efc57d9df707b7 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 79 90 4.9E-15 T 23-10-2018 VMUT_1417 f389f0165ccb2eed75efc57d9df707b7 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 169 182 4.9E-15 T 23-10-2018 VMUT_1417 f389f0165ccb2eed75efc57d9df707b7 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 49 58 4.9E-15 T 23-10-2018 VMUT_1417 f389f0165ccb2eed75efc57d9df707b7 193 Pfam PF00117 Glutamine amidotransferase class-I 6 190 1.2E-52 T 23-10-2018 IPR017926 Glutamine amidotransferase VMUT_0348 09d80bc375077ab24a168aecbda77a08 106 Pfam PF14697 4Fe-4S dicluster domain 36 100 3.1E-11 T 23-10-2018 VMUT_0348 09d80bc375077ab24a168aecbda77a08 106 SUPERFAMILY SSF54862 23 103 6.28E-22 T 23-10-2018 VMUT_0348 09d80bc375077ab24a168aecbda77a08 106 Gene3D G3DSA:3.30.70.20 22 63 7.0E-6 T 23-10-2018 VMUT_0348 09d80bc375077ab24a168aecbda77a08 106 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_0348 09d80bc375077ab24a168aecbda77a08 106 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 17 103 2.2E-33 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 VMUT_0348 09d80bc375077ab24a168aecbda77a08 106 Gene3D G3DSA:3.30.70.20 64 105 7.2E-9 T 23-10-2018 VMUT_1612 c38564e5e546253e878940d0073452a3 335 SUPERFAMILY SSF55326 39 150 1.1E-17 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily VMUT_1612 c38564e5e546253e878940d0073452a3 335 Pfam PF00586 AIR synthase related protein, N-terminal domain 55 150 3.0E-10 T 23-10-2018 IPR016188 PurM-like, N-terminal domain VMUT_1612 c38564e5e546253e878940d0073452a3 335 Gene3D G3DSA:3.30.1330.10 19 152 4.1E-19 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily VMUT_1612 c38564e5e546253e878940d0073452a3 335 SUPERFAMILY SSF56042 158 316 3.87E-14 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily VMUT_1612 c38564e5e546253e878940d0073452a3 335 Gene3D G3DSA:3.90.650.10 159 329 1.1E-17 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily VMUT_1257 928c0e5506bd5667efe5ff5160385350 518 Gene3D G3DSA:3.40.190.10 173 353 6.1E-43 T 23-10-2018 VMUT_1257 928c0e5506bd5667efe5ff5160385350 518 SUPERFAMILY SSF53850 48 418 4.11E-19 T 23-10-2018 VMUT_1257 928c0e5506bd5667efe5ff5160385350 518 Gene3D G3DSA:3.40.190.10 52 377 6.1E-43 T 23-10-2018 VMUT_1257 928c0e5506bd5667efe5ff5160385350 518 Pfam PF01547 Bacterial extracellular solute-binding protein 68 327 4.2E-10 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein VMUT_0934 d43a58cc3bf18ac64db42ac3215b163b 338 SUPERFAMILY SSF52402 28 265 5.03E-42 T 23-10-2018 VMUT_0934 d43a58cc3bf18ac64db42ac3215b163b 338 Gene3D G3DSA:3.40.50.620 5 328 2.2E-65 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_0934 d43a58cc3bf18ac64db42ac3215b163b 338 PIRSF PIRSF004976 1 325 5.6E-89 T 23-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 VMUT_0934 d43a58cc3bf18ac64db42ac3215b163b 338 Pfam PF01171 PP-loop family 54 239 2.0E-10 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 VMUT_0934 d43a58cc3bf18ac64db42ac3215b163b 338 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 213 314 3.6E-21 T 23-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 VMUT_1734 94cc81eefe420ba63dbe7cec2116cccd 157 Pfam PF00571 CBS domain 71 120 5.8E-16 T 23-10-2018 IPR000644 CBS domain VMUT_1734 94cc81eefe420ba63dbe7cec2116cccd 157 Pfam PF00571 CBS domain 6 61 3.0E-13 T 23-10-2018 IPR000644 CBS domain VMUT_1734 94cc81eefe420ba63dbe7cec2116cccd 157 Gene3D G3DSA:3.10.580.10 1 152 1.8E-39 T 23-10-2018 VMUT_1734 94cc81eefe420ba63dbe7cec2116cccd 157 SUPERFAMILY SSF54631 5 120 2.4E-35 T 23-10-2018 VMUT_1734 94cc81eefe420ba63dbe7cec2116cccd 157 SMART SM00116 13 61 2.2E-8 T 23-10-2018 IPR000644 CBS domain VMUT_1734 94cc81eefe420ba63dbe7cec2116cccd 157 SMART SM00116 78 126 2.2E-10 T 23-10-2018 IPR000644 CBS domain VMUT_1661 cf92a1bfe917f0b7b1094822f92586ed 187 SUPERFAMILY SSF89028 17 169 6.67E-12 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 VMUT_1661 cf92a1bfe917f0b7b1094822f92586ed 187 Gene3D G3DSA:1.20.1200.10 27 182 7.4E-6 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 VMUT_1661 cf92a1bfe917f0b7b1094822f92586ed 187 Pfam PF01923 Cobalamin adenosyltransferase 19 162 1.2E-10 T 23-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 VMUT_1479 e738cd8176d8a30052ee057c23d5d54a 502 Pfam PF03787 RAMP superfamily 10 278 6.7E-5 T 23-10-2018 IPR005537 CRISPR type III-associated RAMP protein VMUT_2009 145a67aa179d1836a7d8db6072251a91 138 Gene3D G3DSA:1.20.120.580 2 127 6.7E-9 T 23-10-2018 IPR037038 Bsu32300-like superfamily VMUT_2009 145a67aa179d1836a7d8db6072251a91 138 Pfam PF01934 Protein of unknown function DUF86 15 116 1.1E-16 T 23-10-2018 IPR008201 Protein of unknown function DUF86 VMUT_1487 f3ed4c8056b64ce8f8900de7b427a24d 741 Gene3D G3DSA:3.30.70.2230 440 579 6.8E-10 T 23-10-2018 VMUT_2097 c74e69e185030b52496778da2b9312f8 328 Gene3D G3DSA:3.40.50.10330 15 238 1.2E-45 T 23-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 VMUT_2097 c74e69e185030b52496778da2b9312f8 328 SUPERFAMILY SSF46785 254 321 1.77E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_2097 c74e69e185030b52496778da2b9312f8 328 Gene3D G3DSA:1.10.10.10 241 326 1.2E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_2097 c74e69e185030b52496778da2b9312f8 328 SUPERFAMILY SSF111331 25 228 7.85E-44 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily VMUT_2097 c74e69e185030b52496778da2b9312f8 328 Gene3D G3DSA:2.60.200.30 101 231 1.2E-45 T 23-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 VMUT_2097 c74e69e185030b52496778da2b9312f8 328 Pfam PF01513 ATP-NAD kinase 58 224 4.0E-32 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 VMUT_1474 1270e0e8801060876a1eae6256207939 441 TIGRFAM TIGR02549 CRISPR_DxTHG: CRISPR-associated DxTHG motif protein 185 202 3.6E-9 T 23-10-2018 IPR013383 CRISPR-associated protein DxTHG, conserved site VMUT_1474 1270e0e8801060876a1eae6256207939 441 Gene3D G3DSA:3.40.50.10640 3 306 2.9E-34 T 23-10-2018 VMUT_1474 1270e0e8801060876a1eae6256207939 441 SUPERFAMILY SSF160980 5 433 3.01E-48 T 23-10-2018 VMUT_1474 1270e0e8801060876a1eae6256207939 441 Pfam PF09455 CRISPR-associated (Cas) DxTHG family 8 222 2.1E-13 T 23-10-2018 IPR019016 CRISPR-associated DxTHG protein VMUT_0570 68df493aff83904b72aa47dda91f5b84 157 Gene3D G3DSA:1.20.120.330 41 156 1.3E-33 T 23-10-2018 VMUT_0570 68df493aff83904b72aa47dda91f5b84 157 Pfam PF05942 Archaeal PaREP1/PaREP8 family 39 147 3.6E-27 T 23-10-2018 IPR010268 Archaeal PaREP1 VMUT_1501 23c7f24c424ff8100b0b992fb26ce413 211 Gene3D G3DSA:3.40.50.300 1 211 2.1E-13 T 23-10-2018 VMUT_1501 23c7f24c424ff8100b0b992fb26ce413 211 SUPERFAMILY SSF52540 1 175 4.12E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_2322 9a1264ab2f7dcbf43705eaf11b77a433 401 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 2 369 2.0E-175 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 VMUT_2322 9a1264ab2f7dcbf43705eaf11b77a433 401 Pfam PF01950 Fructose-1,6-bisphosphatase 2 370 2.2E-174 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 VMUT_2322 9a1264ab2f7dcbf43705eaf11b77a433 401 SUPERFAMILY SSF111249 2 370 5.23E-163 T 23-10-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 VMUT_2322 9a1264ab2f7dcbf43705eaf11b77a433 401 PIRSF PIRSF015647 1 386 1.8E-177 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 VMUT_2322 9a1264ab2f7dcbf43705eaf11b77a433 401 Hamap MF_02067 Fructose-1,6-bisphosphate aldolase/phosphatase [fbp]. 1 373 58.839 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 VMUT_1064 2baa4df4b95f87b793baa65bbc5ea768 461 SUPERFAMILY SSF53649 4 421 3.45E-55 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 VMUT_1064 2baa4df4b95f87b793baa65bbc5ea768 461 Pfam PF00884 Sulfatase 4 347 1.1E-35 T 23-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 VMUT_0454 2861bbb26bb1e2ce82714bdd0cf25e00 338 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VMUT_0454 2861bbb26bb1e2ce82714bdd0cf25e00 338 SUPERFAMILY SSF52540 51 331 1.49E-67 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0454 2861bbb26bb1e2ce82714bdd0cf25e00 338 SMART SM00382 51 246 1.9E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0454 2861bbb26bb1e2ce82714bdd0cf25e00 338 Gene3D G3DSA:3.40.50.300 17 338 1.1E-92 T 23-10-2018 VMUT_0454 2861bbb26bb1e2ce82714bdd0cf25e00 338 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 249 314 9.7E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VMUT_0454 2861bbb26bb1e2ce82714bdd0cf25e00 338 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 248 334 1.9E-25 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VMUT_0454 2861bbb26bb1e2ce82714bdd0cf25e00 338 Pfam PF00005 ABC transporter 43 196 4.5E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_0553 4881a5c8162a1350d11b1b9d8dd500c8 397 Gene3D G3DSA:3.90.230.10 153 393 1.8E-58 T 23-10-2018 VMUT_0553 4881a5c8162a1350d11b1b9d8dd500c8 397 Pfam PF01321 Creatinase/Prolidase N-terminal domain 12 154 2.2E-16 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 VMUT_0553 4881a5c8162a1350d11b1b9d8dd500c8 397 SUPERFAMILY SSF55920 153 391 2.09E-55 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like VMUT_0553 4881a5c8162a1350d11b1b9d8dd500c8 397 Gene3D G3DSA:3.40.350.10 2 152 4.7E-28 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal VMUT_0553 4881a5c8162a1350d11b1b9d8dd500c8 397 SUPERFAMILY SSF53092 2 152 2.62E-24 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal VMUT_0553 4881a5c8162a1350d11b1b9d8dd500c8 397 Pfam PF00557 Metallopeptidase family M24 161 377 2.9E-38 T 23-10-2018 IPR000994 Peptidase M24 VMUT_1071 63beb06d865e74427613b94555f8739f 186 Pfam PF05942 Archaeal PaREP1/PaREP8 family 23 146 9.0E-32 T 23-10-2018 IPR010268 Archaeal PaREP1 VMUT_0220 4a85aaafbe8e440b5106caad1b356e50 384 Gene3D G3DSA:3.50.50.60 1 310 5.5E-66 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0220 4a85aaafbe8e440b5106caad1b356e50 384 SUPERFAMILY SSF51905 1 141 5.13E-20 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0220 4a85aaafbe8e440b5106caad1b356e50 384 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 239 3.7E-15 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VMUT_0220 4a85aaafbe8e440b5106caad1b356e50 384 Gene3D G3DSA:3.50.50.60 106 251 5.5E-66 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0220 4a85aaafbe8e440b5106caad1b356e50 384 SUPERFAMILY SSF51905 113 242 8.03E-26 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_2183 3af2514dca7cda043276b63829418ec8 186 Gene3D G3DSA:3.40.50.150 1 171 3.5E-27 T 23-10-2018 VMUT_2183 3af2514dca7cda043276b63829418ec8 186 Pfam PF13489 Methyltransferase domain 39 144 3.2E-15 T 23-10-2018 VMUT_2183 3af2514dca7cda043276b63829418ec8 186 SUPERFAMILY SSF53335 5 148 7.21E-29 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_2048 ec2fd95f833fdf7e0a6920272adb11d4 144 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 10 141 1.9E-24 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 VMUT_2048 ec2fd95f833fdf7e0a6920272adb11d4 144 ProSitePatterns PS00501 Signal peptidases I serine active site. 25 32 - T 23-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 VMUT_2048 ec2fd95f833fdf7e0a6920272adb11d4 144 SUPERFAMILY SSF51306 16 112 1.44E-11 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily VMUT_2145 177e6d60795a98dcd8e1cfe38de9f0d2 426 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 15 255 2.7E-16 T 23-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 VMUT_0662 1916515e8d904948a13f4122025d8fc0 449 Gene3D G3DSA:3.30.2350.20 148 437 3.1E-99 T 23-10-2018 VMUT_0662 1916515e8d904948a13f4122025d8fc0 449 Gene3D G3DSA:1.10.1510.30 192 282 3.1E-99 T 23-10-2018 VMUT_0662 1916515e8d904948a13f4122025d8fc0 449 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 101 114 - T 23-10-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 VMUT_0662 1916515e8d904948a13f4122025d8fc0 449 PIRSF PIRSF037016 55 418 2.5E-49 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 VMUT_0662 1916515e8d904948a13f4122025d8fc0 449 PIRSF PIRSF037016 9 61 6.9 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 VMUT_0662 1916515e8d904948a13f4122025d8fc0 449 PIRSF PIRSF037016 416 447 0.0018 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 VMUT_0662 1916515e8d904948a13f4122025d8fc0 449 SUPERFAMILY SSF55120 12 440 6.19E-73 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 VMUT_0662 1916515e8d904948a13f4122025d8fc0 449 Gene3D G3DSA:3.30.70.3160 63 147 3.1E-99 T 23-10-2018 VMUT_0662 1916515e8d904948a13f4122025d8fc0 449 TIGRFAM TIGR00094 tRNA_TruD_broad: tRNA pseudouridine synthase, TruD family 20 443 5.3E-67 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 VMUT_0662 1916515e8d904948a13f4122025d8fc0 449 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 14 443 26.022 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 VMUT_0662 1916515e8d904948a13f4122025d8fc0 449 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 13 438 1.3E-126 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 VMUT_1779 b0d3f0fea8d50561ff7bc464b0c5c526 343 SUPERFAMILY SSF52540 1 237 7.66E-71 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1779 b0d3f0fea8d50561ff7bc464b0c5c526 343 SUPERFAMILY SSF50331 235 342 5.86E-12 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal VMUT_1779 b0d3f0fea8d50561ff7bc464b0c5c526 343 Pfam PF00005 ABC transporter 25 158 2.5E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_1779 b0d3f0fea8d50561ff7bc464b0c5c526 343 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VMUT_1779 b0d3f0fea8d50561ff7bc464b0c5c526 343 SMART SM00382 27 216 7.6E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_1779 b0d3f0fea8d50561ff7bc464b0c5c526 343 Gene3D G3DSA:3.40.50.300 12 234 8.2E-70 T 23-10-2018 VMUT_0931 13ab9b2e1a66cd9355c50736a1afc4df 476 SUPERFAMILY SSF52540 87 364 1.7E-82 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0931 13ab9b2e1a66cd9355c50736a1afc4df 476 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 18 83 5.8E-7 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VMUT_0931 13ab9b2e1a66cd9355c50736a1afc4df 476 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 140 358 1.2E-65 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VMUT_0931 13ab9b2e1a66cd9355c50736a1afc4df 476 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 11 467 55.388 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 VMUT_0931 13ab9b2e1a66cd9355c50736a1afc4df 476 Gene3D G3DSA:3.40.50.12240 6 467 2.1E-167 T 23-10-2018 VMUT_1153 7719f42efdc55c38a178e21e0550cc6a 220 SMART SM00895 79 205 8.3E-25 T 23-10-2018 IPR011711 GntR, C-terminal VMUT_1153 7719f42efdc55c38a178e21e0550cc6a 220 SUPERFAMILY SSF46785 5 96 2.94E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_1153 7719f42efdc55c38a178e21e0550cc6a 220 Gene3D G3DSA:1.20.120.530 72 213 7.5E-32 T 23-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VMUT_1153 7719f42efdc55c38a178e21e0550cc6a 220 SUPERFAMILY SSF48008 75 211 8.89E-29 T 23-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VMUT_1153 7719f42efdc55c38a178e21e0550cc6a 220 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 64 3.7E-17 T 23-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VMUT_1153 7719f42efdc55c38a178e21e0550cc6a 220 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 1.2E-5 T 23-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VMUT_1153 7719f42efdc55c38a178e21e0550cc6a 220 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 1.2E-5 T 23-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VMUT_1153 7719f42efdc55c38a178e21e0550cc6a 220 Pfam PF07729 FCD domain 79 204 7.4E-27 T 23-10-2018 IPR011711 GntR, C-terminal VMUT_1153 7719f42efdc55c38a178e21e0550cc6a 220 SMART SM00345 12 69 2.2E-14 T 23-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VMUT_1153 7719f42efdc55c38a178e21e0550cc6a 220 Gene3D G3DSA:1.10.10.10 5 70 2.0E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_1351 883a8c13a11665cd76cb237bbcbf7cb6 282 SUPERFAMILY SSF56235 2 268 1.13E-12 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VMUT_1351 883a8c13a11665cd76cb237bbcbf7cb6 282 Gene3D G3DSA:3.60.20.10 2 279 6.7E-12 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VMUT_1351 883a8c13a11665cd76cb237bbcbf7cb6 282 Pfam PF13522 Glutamine amidotransferase domain 87 199 3.9E-9 T 23-10-2018 VMUT_0764 bd20c10127f463494d21236fc0f8d814 973 Pfam PF09261 Alpha mannosidase middle domain 490 560 5.3E-11 T 23-10-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 VMUT_0764 bd20c10127f463494d21236fc0f8d814 973 SUPERFAMILY SSF88688 489 587 3.6E-13 T 23-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily VMUT_0764 bd20c10127f463494d21236fc0f8d814 973 Gene3D G3DSA:2.70.98.30 643 880 3.1E-17 T 23-10-2018 VMUT_0764 bd20c10127f463494d21236fc0f8d814 973 SUPERFAMILY SSF88713 227 488 2.18E-58 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 VMUT_0764 bd20c10127f463494d21236fc0f8d814 973 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 232 476 9.5E-62 T 23-10-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 VMUT_0764 bd20c10127f463494d21236fc0f8d814 973 SMART SM00872 490 561 1.4E-10 T 23-10-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 VMUT_0764 bd20c10127f463494d21236fc0f8d814 973 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 587 969 8.2E-52 T 23-10-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 VMUT_0764 bd20c10127f463494d21236fc0f8d814 973 Gene3D G3DSA:1.20.1270.50 493 582 2.7E-6 T 23-10-2018 IPR037094 Glycoside hydrolase family 38, central domain superfamily GO:0004559|GO:0006013 VMUT_0764 bd20c10127f463494d21236fc0f8d814 973 Gene3D G3DSA:3.20.110.10 228 489 4.4E-51 T 23-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily VMUT_0764 bd20c10127f463494d21236fc0f8d814 973 SUPERFAMILY SSF74650 584 971 3.45E-72 T 23-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 VMUT_0106 5ba45b738351ee7176cffed545b25642 514 Pfam PF00535 Glycosyl transferase family 2 96 267 9.7E-19 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VMUT_0106 5ba45b738351ee7176cffed545b25642 514 Gene3D G3DSA:3.90.550.10 85 303 1.4E-35 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0106 5ba45b738351ee7176cffed545b25642 514 SUPERFAMILY SSF53448 89 352 1.09E-41 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0919 70400b101c091baf4e0611da98887201 360 Pfam PF01497 Periplasmic binding protein 67 299 2.9E-26 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain VMUT_0919 70400b101c091baf4e0611da98887201 360 Gene3D G3DSA:3.40.50.1980 36 359 4.0E-45 T 23-10-2018 VMUT_0919 70400b101c091baf4e0611da98887201 360 SUPERFAMILY SSF53807 50 330 3.41E-51 T 23-10-2018 VMUT_0378 089936fee2dd86dafe15f315edfbd898 387 PIRSF PIRSF000429 1 386 3.9E-61 T 23-10-2018 IPR002155 Thiolase GO:0016747 VMUT_0378 089936fee2dd86dafe15f315edfbd898 387 Gene3D G3DSA:3.40.47.10 1 387 7.4E-120 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_0378 089936fee2dd86dafe15f315edfbd898 387 SUPERFAMILY SSF53901 7 229 3.91E-44 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_0378 089936fee2dd86dafe15f315edfbd898 387 Pfam PF00108 Thiolase, N-terminal domain 13 223 1.2E-18 T 23-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 VMUT_0378 089936fee2dd86dafe15f315edfbd898 387 Pfam PF02803 Thiolase, C-terminal domain 261 355 3.5E-11 T 23-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 VMUT_0378 089936fee2dd86dafe15f315edfbd898 387 SUPERFAMILY SSF53901 230 384 5.62E-31 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_1553 c5d0a23919be92e277e1a5da82cece9e 207 SUPERFAMILY SSF103473 3 203 2.22E-8 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_1423 8eb6f3ad42ea00bfcf45ce9feb504e3e 247 Gene3D G3DSA:3.20.20.70 3 247 1.1E-58 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_1423 8eb6f3ad42ea00bfcf45ce9feb504e3e 247 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 42 59 - T 23-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 VMUT_1423 8eb6f3ad42ea00bfcf45ce9feb504e3e 247 SUPERFAMILY SSF51366 23 239 5.81E-50 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 VMUT_1423 8eb6f3ad42ea00bfcf45ce9feb504e3e 247 Pfam PF00218 Indole-3-glycerol phosphate synthase 19 240 2.4E-49 T 23-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 VMUT_1891 39d6d5527cb22b0cc51fd50bcc04ce89 303 SUPERFAMILY SSF48557 1 57 5.18E-7 T 23-10-2018 IPR008948 L-Aspartase-like GO:0003824 VMUT_1891 39d6d5527cb22b0cc51fd50bcc04ce89 303 SUPERFAMILY SSF51430 52 296 1.7E-26 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VMUT_1891 39d6d5527cb22b0cc51fd50bcc04ce89 303 Pfam PF00248 Aldo/keto reductase family 49 293 2.5E-16 T 23-10-2018 IPR023210 NADP-dependent oxidoreductase domain VMUT_1891 39d6d5527cb22b0cc51fd50bcc04ce89 303 Gene3D G3DSA:3.20.20.100 45 301 2.1E-24 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VMUT_1891 39d6d5527cb22b0cc51fd50bcc04ce89 303 Pfam PF00221 Aromatic amino acid lyase 1 49 2.2E-7 T 23-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 VMUT_1282 d1ce12e4c0000c9a1818b76a4fa90946 499 Gene3D G3DSA:3.40.50.12780 8 407 2.3E-90 T 23-10-2018 VMUT_1282 d1ce12e4c0000c9a1818b76a4fa90946 499 Pfam PF13193 AMP-binding enzyme C-terminal domain 425 497 4.1E-12 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VMUT_1282 d1ce12e4c0000c9a1818b76a4fa90946 499 SUPERFAMILY SSF56801 10 498 4.32E-113 T 23-10-2018 VMUT_1282 d1ce12e4c0000c9a1818b76a4fa90946 499 Pfam PF00501 AMP-binding enzyme 24 415 5.6E-79 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VMUT_1282 d1ce12e4c0000c9a1818b76a4fa90946 499 Gene3D G3DSA:3.30.300.30 410 497 5.3E-19 T 23-10-2018 VMUT_0798 0da489d8cdca4f8afd6ab8518f335ca0 264 SUPERFAMILY SSF56317 1 247 4.97E-38 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily VMUT_0798 0da489d8cdca4f8afd6ab8518f335ca0 264 Pfam PF00795 Carbon-nitrogen hydrolase 27 236 1.6E-18 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 VMUT_0798 0da489d8cdca4f8afd6ab8518f335ca0 264 Gene3D G3DSA:3.60.110.10 1 253 3.9E-37 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily VMUT_0100 3b74fd5af1e12ee236540cc898ae91c7 226 Pfam PF00483 Nucleotidyl transferase 5 220 4.0E-22 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 VMUT_0100 3b74fd5af1e12ee236540cc898ae91c7 226 Gene3D G3DSA:3.90.550.10 2 225 1.0E-44 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0100 3b74fd5af1e12ee236540cc898ae91c7 226 SUPERFAMILY SSF53448 2 222 2.6E-46 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0041 e3b873fd937e26bce85820c6b78409f0 489 Gene3D G3DSA:3.20.20.80 2 489 4.3E-171 T 23-10-2018 VMUT_0041 e3b873fd937e26bce85820c6b78409f0 489 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 9 23 - T 23-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site VMUT_0041 e3b873fd937e26bce85820c6b78409f0 489 SUPERFAMILY SSF51445 4 477 2.01E-129 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily VMUT_0041 e3b873fd937e26bce85820c6b78409f0 489 PRINTS PR00131 Glycosyl hydrolase family 1 signature 395 406 4.9E-21 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 VMUT_0041 e3b873fd937e26bce85820c6b78409f0 489 PRINTS PR00131 Glycosyl hydrolase family 1 signature 440 452 4.9E-21 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 VMUT_0041 e3b873fd937e26bce85820c6b78409f0 489 PRINTS PR00131 Glycosyl hydrolase family 1 signature 416 433 4.9E-21 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 VMUT_0041 e3b873fd937e26bce85820c6b78409f0 489 PRINTS PR00131 Glycosyl hydrolase family 1 signature 383 391 4.9E-21 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 VMUT_0041 e3b873fd937e26bce85820c6b78409f0 489 PRINTS PR00131 Glycosyl hydrolase family 1 signature 312 326 4.9E-21 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 VMUT_0041 e3b873fd937e26bce85820c6b78409f0 489 Pfam PF00232 Glycosyl hydrolase family 1 4 93 4.7E-5 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 VMUT_0041 e3b873fd937e26bce85820c6b78409f0 489 Pfam PF00232 Glycosyl hydrolase family 1 125 469 5.9E-58 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 VMUT_0041 e3b873fd937e26bce85820c6b78409f0 489 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 383 391 - T 23-10-2018 IPR018120 Glycoside hydrolase family 1, active site VMUT_0451 7f560dd3d2c78c0ac51d949703ffa4d4 192 Gene3D G3DSA:3.20.20.140 7 183 1.9E-14 T 23-10-2018 VMUT_0451 7f560dd3d2c78c0ac51d949703ffa4d4 192 Pfam PF01876 RNase P subunit p30 52 164 2.3E-12 T 23-10-2018 IPR002738 RNase P subunit p30 GO:0004540|GO:0008033 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 VMUT_0451 7f560dd3d2c78c0ac51d949703ffa4d4 192 SUPERFAMILY SSF89550 7 176 2.28E-12 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 VMUT_1174 b0045bdaa579082a505d2cfb92b96a8a 356 Gene3D G3DSA:3.40.50.720 1 106 2.3E-13 T 23-10-2018 VMUT_1174 b0045bdaa579082a505d2cfb92b96a8a 356 SUPERFAMILY SSF51735 1 141 8.14E-16 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1174 b0045bdaa579082a505d2cfb92b96a8a 356 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 112 1.2E-11 T 23-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 VMUT_1174 b0045bdaa579082a505d2cfb92b96a8a 356 Gene3D G3DSA:3.40.50.720 293 356 2.5E-8 T 23-10-2018 VMUT_1174 b0045bdaa579082a505d2cfb92b96a8a 356 Gene3D G3DSA:3.30.360.10 119 281 6.3E-24 T 23-10-2018 VMUT_1174 b0045bdaa579082a505d2cfb92b96a8a 356 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 117 346 2.0E-7 T 23-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 VMUT_0608 88bb3937dc4c8386f908cf7fce985c97 292 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 8 281 3.0E-90 T 23-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 VMUT_0608 88bb3937dc4c8386f908cf7fce985c97 292 Pfam PF05681 Fumarate hydratase (Fumerase) 10 279 4.0E-81 T 23-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 VMUT_0300 a9a1f24011e5bf5d735c7f69e93c27f8 140 Gene3D G3DSA:3.30.310.60 79 135 1.2E-23 T 23-10-2018 IPR037156 Like-Sm ribonucleoprotein, C-terminal domain superfamily VMUT_0300 a9a1f24011e5bf5d735c7f69e93c27f8 140 SUPERFAMILY SSF50182 14 130 7.71E-16 T 23-10-2018 IPR010920 LSM domain superfamily VMUT_0300 a9a1f24011e5bf5d735c7f69e93c27f8 140 Gene3D G3DSA:2.30.30.100 11 76 2.4E-14 T 23-10-2018 VMUT_0300 a9a1f24011e5bf5d735c7f69e93c27f8 140 Pfam PF01423 LSM domain 15 57 1.3E-7 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type VMUT_0300 a9a1f24011e5bf5d735c7f69e93c27f8 140 SMART SM00651 13 74 0.0069 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type VMUT_0300 a9a1f24011e5bf5d735c7f69e93c27f8 140 Pfam PF14894 Lsm C-terminal 82 139 9.1E-24 T 23-10-2018 IPR028277 Lsm, C-terminal VMUT_0005 e86704969d8abb1ed99f333149193ea2 122 SUPERFAMILY SSF51182 17 112 1.04E-24 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily VMUT_0005 e86704969d8abb1ed99f333149193ea2 122 Pfam PF07883 Cupin domain 43 109 1.7E-14 T 23-10-2018 IPR013096 Cupin 2, conserved barrel VMUT_0005 e86704969d8abb1ed99f333149193ea2 122 Gene3D G3DSA:2.60.120.10 1 115 3.3E-27 T 23-10-2018 IPR014710 RmlC-like jelly roll fold VMUT_0197 ba9d18bbdcd6e76c3092d84832e38995 767 Gene3D G3DSA:3.40.50.300 563 683 3.9E-8 T 23-10-2018 VMUT_0197 ba9d18bbdcd6e76c3092d84832e38995 767 SUPERFAMILY SSF52540 550 694 1.36E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0090 3a7ace584482d3b1dee992f853b06951 198 SUPERFAMILY SSF53335 15 179 1.21E-35 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_0090 3a7ace584482d3b1dee992f853b06951 198 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 124 136 2.6E-5 T 23-10-2018 VMUT_0090 3a7ace584482d3b1dee992f853b06951 198 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 60 74 2.6E-5 T 23-10-2018 VMUT_0090 3a7ace584482d3b1dee992f853b06951 198 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 138 162 2.6E-5 T 23-10-2018 VMUT_0090 3a7ace584482d3b1dee992f853b06951 198 Gene3D G3DSA:3.40.50.150 6 195 2.3E-39 T 23-10-2018 VMUT_0090 3a7ace584482d3b1dee992f853b06951 198 Pfam PF05175 Methyltransferase small domain 27 190 4.5E-40 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 VMUT_0922 ad836ba7aafe2cc331a44feca1e9ca40 612 Gene3D G3DSA:1.10.569.10 243 423 9.2E-119 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 VMUT_0922 ad836ba7aafe2cc331a44feca1e9ca40 612 Gene3D G3DSA:3.60.9.10 1 214 7.7E-77 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily VMUT_0922 ad836ba7aafe2cc331a44feca1e9ca40 612 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 208 4.0E-72 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_0922 ad836ba7aafe2cc331a44feca1e9ca40 612 Gene3D G3DSA:1.10.599.10 241 598 9.2E-119 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 VMUT_0922 ad836ba7aafe2cc331a44feca1e9ca40 612 SUPERFAMILY SSF48310 227 607 1.03E-109 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_0922 ad836ba7aafe2cc331a44feca1e9ca40 612 SUPERFAMILY SSF56228 1 214 5.62E-67 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily VMUT_0922 ad836ba7aafe2cc331a44feca1e9ca40 612 SMART SM00790 4 210 4.5E-102 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_0922 ad836ba7aafe2cc331a44feca1e9ca40 612 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 230 598 7.7E-111 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 VMUT_0838 5cac12f9127f49951d6671a056e07849 156 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 3 26 4.8E-7 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal VMUT_0535 842858bcbff9befca6e0b1ba57a4356b 428 SUPERFAMILY SSF103473 12 417 3.79E-82 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_0535 842858bcbff9befca6e0b1ba57a4356b 428 Gene3D G3DSA:1.20.1250.20 6 423 8.8E-78 T 23-10-2018 VMUT_0535 842858bcbff9befca6e0b1ba57a4356b 428 Pfam PF07690 Major Facilitator Superfamily 25 383 3.3E-55 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_0842 e0a7fa6e767284e6140b1e40c0b10d44 294 PIRSF PIRSF005355 1 292 8.5E-52 T 23-10-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 VMUT_0842 e0a7fa6e767284e6140b1e40c0b10d44 294 Pfam PF01040 UbiA prenyltransferase family 26 271 1.6E-30 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 VMUT_1414 da8264073c537898e2f5c71d0d8dae26 441 Pfam PF01979 Amidohydrolase family 56 419 7.1E-16 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VMUT_1414 da8264073c537898e2f5c71d0d8dae26 441 SUPERFAMILY SSF51338 23 69 8.63E-5 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VMUT_1414 da8264073c537898e2f5c71d0d8dae26 441 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 24 422 3.0E-99 T 23-10-2018 VMUT_1414 da8264073c537898e2f5c71d0d8dae26 441 ProSitePatterns PS00483 Dihydroorotase signature 2. 304 315 - T 23-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VMUT_1414 da8264073c537898e2f5c71d0d8dae26 441 Hamap MF_00220_A Dihydroorotase [pyrC]. 11 428 60.939 T 23-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VMUT_1414 da8264073c537898e2f5c71d0d8dae26 441 SUPERFAMILY SSF51556 60 365 4.7E-71 T 23-10-2018 IPR032466 Metal-dependent hydrolase VMUT_1414 da8264073c537898e2f5c71d0d8dae26 441 Gene3D G3DSA:3.20.20.140 59 406 2.6E-88 T 23-10-2018 VMUT_1414 da8264073c537898e2f5c71d0d8dae26 441 ProSitePatterns PS00482 Dihydroorotase signature 1. 63 71 - T 23-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VMUT_1414 da8264073c537898e2f5c71d0d8dae26 441 SUPERFAMILY SSF51338 315 430 2.56E-14 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VMUT_1414 da8264073c537898e2f5c71d0d8dae26 441 Gene3D G3DSA:2.30.40.10 18 421 2.6E-88 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VMUT_1537 3fb8f305e7ac21e17cdeeb3c16bdcc7c 358 TIGRFAM TIGR01902 dapE-lys-deAc: N-acetyl-ornithine/N-acetyl-lysine deacetylase 10 354 7.0E-72 T 23-10-2018 IPR010175 [LysW]-lysine/[LysW]-ornithine hydrolase GO:0005737|GO:0008270|GO:0009085|GO:0016811|GO:0050897 VMUT_1537 3fb8f305e7ac21e17cdeeb3c16bdcc7c 358 SUPERFAMILY SSF53187 6 355 5.19E-50 T 23-10-2018 VMUT_1537 3fb8f305e7ac21e17cdeeb3c16bdcc7c 358 SUPERFAMILY SSF55031 166 270 1.64E-15 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VMUT_1537 3fb8f305e7ac21e17cdeeb3c16bdcc7c 358 Hamap MF_01120 [LysW]-lysine/[LysW]-ornithine hydrolase [lysK]. 6 354 31.989 T 23-10-2018 IPR010175 [LysW]-lysine/[LysW]-ornithine hydrolase GO:0005737|GO:0008270|GO:0009085|GO:0016811|GO:0050897 VMUT_1537 3fb8f305e7ac21e17cdeeb3c16bdcc7c 358 Pfam PF01546 Peptidase family M20/M25/M40 64 350 2.1E-26 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 VMUT_1537 3fb8f305e7ac21e17cdeeb3c16bdcc7c 358 Pfam PF07687 Peptidase dimerisation domain 159 252 3.2E-13 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain VMUT_1537 3fb8f305e7ac21e17cdeeb3c16bdcc7c 358 Gene3D G3DSA:3.40.630.10 15 345 3.0E-84 T 23-10-2018 VMUT_1537 3fb8f305e7ac21e17cdeeb3c16bdcc7c 358 Gene3D G3DSA:3.30.70.360 159 268 3.0E-84 T 23-10-2018 VMUT_0091 2172205e081227d93f681d4e20b3d11f 285 SUPERFAMILY SSF103481 40 138 3.4E-13 T 23-10-2018 VMUT_0091 2172205e081227d93f681d4e20b3d11f 285 SUPERFAMILY SSF103481 193 283 4.71E-7 T 23-10-2018 VMUT_0091 2172205e081227d93f681d4e20b3d11f 285 Pfam PF00892 EamA-like transporter family 8 134 1.3E-16 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VMUT_0091 2172205e081227d93f681d4e20b3d11f 285 Pfam PF00892 EamA-like transporter family 147 284 2.5E-15 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VMUT_0465 7b286271ddc8ff1df1e52a7bf12612c9 251 ProSitePatterns PS01251 Proliferating cell nuclear antigen signature 1. 36 59 - T 23-10-2018 IPR022659 Proliferating cell nuclear antigen, PCNA, conserved site Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 VMUT_0465 7b286271ddc8ff1df1e52a7bf12612c9 251 SUPERFAMILY SSF55979 5 127 6.06E-28 T 23-10-2018 VMUT_0465 7b286271ddc8ff1df1e52a7bf12612c9 251 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 4 250 30.35 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 VMUT_0465 7b286271ddc8ff1df1e52a7bf12612c9 251 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 109 131 1.3E-9 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 VMUT_0465 7b286271ddc8ff1df1e52a7bf12612c9 251 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 12 31 1.3E-9 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 VMUT_0465 7b286271ddc8ff1df1e52a7bf12612c9 251 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 236 251 1.3E-9 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 VMUT_0465 7b286271ddc8ff1df1e52a7bf12612c9 251 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 36 54 1.3E-9 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 VMUT_0465 7b286271ddc8ff1df1e52a7bf12612c9 251 SUPERFAMILY SSF55979 127 251 6.06E-25 T 23-10-2018 VMUT_0465 7b286271ddc8ff1df1e52a7bf12612c9 251 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 130 248 1.0E-8 T 23-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 VMUT_0465 7b286271ddc8ff1df1e52a7bf12612c9 251 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 11 107 1.7E-11 T 23-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 VMUT_0465 7b286271ddc8ff1df1e52a7bf12612c9 251 Gene3D G3DSA:3.70.10.10 3 245 1.0E-74 T 23-10-2018 VMUT_0465 7b286271ddc8ff1df1e52a7bf12612c9 251 TIGRFAM TIGR00590 pcna: proliferating cell nuclear antigen (pcna) 10 251 4.9E-30 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 VMUT_0528 01ba3f571073c7d0a6b9a06023acfe69 472 Pfam PF03486 HI0933-like protein 3 37 1.5E-5 T 23-10-2018 VMUT_0528 01ba3f571073c7d0a6b9a06023acfe69 472 Pfam PF01134 Glucose inhibited division protein A 389 455 5.0E-4 T 23-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 VMUT_0528 01ba3f571073c7d0a6b9a06023acfe69 472 Gene3D G3DSA:3.30.9.10 226 258 1.2E-6 T 23-10-2018 VMUT_0528 01ba3f571073c7d0a6b9a06023acfe69 472 SUPERFAMILY SSF51905 1 456 5.52E-34 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0528 01ba3f571073c7d0a6b9a06023acfe69 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 6.2E-8 T 23-10-2018 VMUT_0528 01ba3f571073c7d0a6b9a06023acfe69 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 413 435 6.2E-8 T 23-10-2018 VMUT_0528 01ba3f571073c7d0a6b9a06023acfe69 472 Gene3D G3DSA:3.50.50.60 404 471 2.0E-6 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0528 01ba3f571073c7d0a6b9a06023acfe69 472 Gene3D G3DSA:3.50.50.60 152 225 1.2E-6 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0528 01ba3f571073c7d0a6b9a06023acfe69 472 Gene3D G3DSA:3.50.50.60 1 94 9.0E-15 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0528 01ba3f571073c7d0a6b9a06023acfe69 472 PIRSF PIRSF038984 1 93 4.0E-6 T 23-10-2018 IPR028348 FAD dependent protein VMUT_0528 01ba3f571073c7d0a6b9a06023acfe69 472 PIRSF PIRSF038984 123 462 9.5E-31 T 23-10-2018 IPR028348 FAD dependent protein VMUT_0473 84d25e51ed22f65f6b0db9611b1a83a8 268 SUPERFAMILY SSF74650 10 265 4.46E-53 T 23-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 VMUT_0473 84d25e51ed22f65f6b0db9611b1a83a8 268 Pfam PF01263 Aldose 1-epimerase 11 263 4.9E-37 T 23-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 VMUT_0473 84d25e51ed22f65f6b0db9611b1a83a8 268 Gene3D G3DSA:2.70.98.10 3 266 2.2E-54 T 23-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 VMUT_0112 847e515fab9b3353db6fde6be019336a 212 Gene3D G3DSA:2.30.110.10 29 203 5.6E-37 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 VMUT_0112 847e515fab9b3353db6fde6be019336a 212 SUPERFAMILY SSF50475 34 201 1.03E-36 T 23-10-2018 VMUT_0112 847e515fab9b3353db6fde6be019336a 212 Pfam PF01613 Flavin reductase like domain 40 178 2.2E-19 T 23-10-2018 IPR002563 Flavin reductase like domain GO:0010181 VMUT_0112 847e515fab9b3353db6fde6be019336a 212 SMART SM00903 37 178 3.6E-8 T 23-10-2018 IPR002563 Flavin reductase like domain GO:0010181 VMUT_1401 bf921eab9f33f4195a5a8487b9d55e65 264 Pfam PF06023 CRISPR-associated exonuclease Csa1 8 264 3.4E-58 T 23-10-2018 IPR009260 CRISPR-associated exonuclease Csa1 VMUT_1401 bf921eab9f33f4195a5a8487b9d55e65 264 TIGRFAM TIGR01896 cas_AF1879: CRISPR-associated protein Cas4/Csa1, subtype I-A/APERN 16 263 2.8E-58 T 23-10-2018 IPR009260 CRISPR-associated exonuclease Csa1 VMUT_1797 23ce3906140f3146121146409c4425e5 92 Pfam PF01780 Ribosomal L37ae protein family 5 84 8.0E-30 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_1797 23ce3906140f3146121146409c4425e5 92 SUPERFAMILY SSF57829 12 81 1.4E-24 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 VMUT_1797 23ce3906140f3146121146409c4425e5 92 Hamap MF_00327 50S ribosomal protein L37Ae [rpl37ae]. 5 74 23.085 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_1797 23ce3906140f3146121146409c4425e5 92 Gene3D G3DSA:2.20.25.30 3 92 3.8E-28 T 23-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_2106 ce811dfc89dd1439a40ecd16180150bf 398 SMART SM00933 66 355 6.6E-21 T 23-10-2018 IPR018977 NurA domain VMUT_2106 ce811dfc89dd1439a40ecd16180150bf 398 Pfam PF09376 NurA domain 67 354 6.6E-17 T 23-10-2018 IPR018977 NurA domain VMUT_2326 0b09c9f1ec9dc47bda25874f898e36ba 220 SMART SM00987 44 208 2.4E-25 T 23-10-2018 VMUT_2326 0b09c9f1ec9dc47bda25874f898e36ba 220 Gene3D G3DSA:3.40.470.10 4 217 6.0E-57 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VMUT_2326 0b09c9f1ec9dc47bda25874f898e36ba 220 SUPERFAMILY SSF52141 14 213 3.2E-43 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VMUT_2326 0b09c9f1ec9dc47bda25874f898e36ba 220 Pfam PF03167 Uracil DNA glycosylase superfamily 50 208 1.0E-32 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VMUT_2326 0b09c9f1ec9dc47bda25874f898e36ba 220 SMART SM00986 44 208 2.4E-25 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VMUT_0317 2565f031f6a5dafd85213a0900e95df1 235 Pfam PF06508 Queuosine biosynthesis protein QueC 4 208 8.3E-47 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 VMUT_0317 2565f031f6a5dafd85213a0900e95df1 235 SUPERFAMILY SSF52402 2 218 3.53E-49 T 23-10-2018 VMUT_0317 2565f031f6a5dafd85213a0900e95df1 235 Gene3D G3DSA:3.40.50.620 1 212 9.5E-55 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_0317 2565f031f6a5dafd85213a0900e95df1 235 PIRSF PIRSF006293 1 220 1.4E-52 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 VMUT_1467 a86eae1f8f056aa5fee3ecd84b015995 125 SUPERFAMILY SSF55159 34 116 7.72E-17 T 23-10-2018 IPR036877 SUI1 domain superfamily GO:0003743|GO:0006413 VMUT_1467 a86eae1f8f056aa5fee3ecd84b015995 125 Pfam PF01253 Translation initiation factor SUI1 40 111 9.3E-16 T 23-10-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 VMUT_1467 a86eae1f8f056aa5fee3ecd84b015995 125 Gene3D G3DSA:3.30.780.10 39 119 5.9E-22 T 23-10-2018 VMUT_0029 afb314ede586594f47fd59ebb3bc1932 147 SMART SM00116 77 124 5.1E-6 T 23-10-2018 IPR000644 CBS domain VMUT_0029 afb314ede586594f47fd59ebb3bc1932 147 SMART SM00116 12 60 0.0012 T 23-10-2018 IPR000644 CBS domain VMUT_0029 afb314ede586594f47fd59ebb3bc1932 147 Gene3D G3DSA:3.10.580.10 1 142 2.2E-27 T 23-10-2018 VMUT_0029 afb314ede586594f47fd59ebb3bc1932 147 Pfam PF00571 CBS domain 12 60 8.8E-9 T 23-10-2018 IPR000644 CBS domain VMUT_0029 afb314ede586594f47fd59ebb3bc1932 147 Pfam PF00571 CBS domain 77 121 7.0E-9 T 23-10-2018 IPR000644 CBS domain VMUT_0029 afb314ede586594f47fd59ebb3bc1932 147 SUPERFAMILY SSF54631 3 121 1.64E-26 T 23-10-2018 VMUT_0975 5ea77cb20b91343f3c833959340a89c3 663 Gene3D G3DSA:3.30.365.10 119 335 1.4E-69 T 23-10-2018 VMUT_0975 5ea77cb20b91343f3c833959340a89c3 663 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 159 641 4.4E-95 T 23-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 VMUT_0975 5ea77cb20b91343f3c833959340a89c3 663 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 12 118 3.0E-19 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead VMUT_0975 5ea77cb20b91343f3c833959340a89c3 663 Gene3D G3DSA:3.90.1170.50 25 118 1.4E-69 T 23-10-2018 VMUT_0975 5ea77cb20b91343f3c833959340a89c3 663 Gene3D G3DSA:3.30.365.10 12 261 1.4E-69 T 23-10-2018 VMUT_0975 5ea77cb20b91343f3c833959340a89c3 663 SMART SM01008 11 118 1.1E-29 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead VMUT_0975 5ea77cb20b91343f3c833959340a89c3 663 Gene3D G3DSA:3.30.365.10 418 558 1.8E-62 T 23-10-2018 VMUT_0975 5ea77cb20b91343f3c833959340a89c3 663 SUPERFAMILY SSF56003 110 660 2.09E-114 T 23-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 VMUT_0975 5ea77cb20b91343f3c833959340a89c3 663 Gene3D G3DSA:3.30.365.10 343 660 1.8E-62 T 23-10-2018 VMUT_0975 5ea77cb20b91343f3c833959340a89c3 663 SUPERFAMILY SSF54665 1 137 2.09E-31 T 23-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily VMUT_0945 5d8eb5b72c87e6ac5ed17192d790e2a1 626 PIRSF PIRSF006060 490 623 250.0 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_0945 5d8eb5b72c87e6ac5ed17192d790e2a1 626 PIRSF PIRSF006060 21 494 3.3E-62 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_0945 5d8eb5b72c87e6ac5ed17192d790e2a1 626 Pfam PF13520 Amino acid permease 43 459 2.4E-34 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_0945 5d8eb5b72c87e6ac5ed17192d790e2a1 626 Gene3D G3DSA:1.20.1740.10 35 502 4.4E-56 T 23-10-2018 VMUT_0083 e470012cd13332d9c5dc8f6e23d8010e 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 126 308 4.6E-27 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VMUT_0083 e470012cd13332d9c5dc8f6e23d8010e 311 Gene3D G3DSA:1.10.3720.10 110 304 9.8E-17 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_0083 e470012cd13332d9c5dc8f6e23d8010e 311 SUPERFAMILY SSF161098 116 290 4.91E-19 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_2301 2855bbf628a01997fc735c00649d6d4b 277 Pfam PF01048 Phosphorylase superfamily 25 233 4.4E-38 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 VMUT_2301 2855bbf628a01997fc735c00649d6d4b 277 Gene3D G3DSA:3.40.50.1580 9 258 2.3E-75 T 23-10-2018 VMUT_2301 2855bbf628a01997fc735c00649d6d4b 277 TIGRFAM TIGR01718 Uridine-psphlse: uridine phosphorylase 12 251 2.3E-94 T 23-10-2018 IPR010058 Uridine phosphorylase GO:0004850|GO:0005737|GO:0009166 KEGG: 00240+2.4.2.3|KEGG: 00983+2.4.2.3|MetaCyc: PWY-5532 VMUT_2301 2855bbf628a01997fc735c00649d6d4b 277 SUPERFAMILY SSF53167 12 248 1.57E-68 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 VMUT_0763 82a5310cba016d92d0b796fac668437d 160 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 29 141 5.4E-17 T 23-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 VMUT_0763 82a5310cba016d92d0b796fac668437d 160 Gene3D G3DSA:3.10.129.10 6 142 2.7E-28 T 23-10-2018 VMUT_0763 82a5310cba016d92d0b796fac668437d 160 Pfam PF03061 Thioesterase superfamily 57 132 2.8E-10 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 VMUT_0763 82a5310cba016d92d0b796fac668437d 160 SUPERFAMILY SSF54637 20 146 1.11E-26 T 23-10-2018 IPR029069 HotDog domain superfamily VMUT_1906 e79f0056eb5b95f09e5b3fefc3e3118b 248 Pfam PF01061 ABC-2 type transporter 30 205 2.7E-14 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 VMUT_2119 7f0b7c27d77a09fe45663440c3d1e55d 333 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 69 87 5.6E-7 T 23-10-2018 IPR001270 ClpA/B family GO:0005524 VMUT_2119 7f0b7c27d77a09fe45663440c3d1e55d 333 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 145 163 5.6E-7 T 23-10-2018 IPR001270 ClpA/B family GO:0005524 VMUT_2119 7f0b7c27d77a09fe45663440c3d1e55d 333 SUPERFAMILY SSF52540 39 296 2.26E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_2119 7f0b7c27d77a09fe45663440c3d1e55d 333 Pfam PF07728 AAA domain (dynein-related subfamily) 68 205 2.2E-20 T 23-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 VMUT_2119 7f0b7c27d77a09fe45663440c3d1e55d 333 PIRSF PIRSF002849 15 326 6.9E-35 T 23-10-2018 VMUT_2119 7f0b7c27d77a09fe45663440c3d1e55d 333 SMART SM00382 65 216 1.6E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_2119 7f0b7c27d77a09fe45663440c3d1e55d 333 Gene3D G3DSA:3.40.50.300 50 223 9.4E-37 T 23-10-2018 VMUT_1086 f4e85b8cb63a1aa2f4941862bda641fb 188 Pfam PF05050 Methyltransferase FkbM domain 9 162 1.9E-19 T 23-10-2018 IPR006342 Methyltransferase FkbM VMUT_1086 f4e85b8cb63a1aa2f4941862bda641fb 188 Gene3D G3DSA:3.40.50.150 1 181 6.6E-39 T 23-10-2018 VMUT_1086 f4e85b8cb63a1aa2f4941862bda641fb 188 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 6 144 7.9E-34 T 23-10-2018 IPR006342 Methyltransferase FkbM VMUT_1086 f4e85b8cb63a1aa2f4941862bda641fb 188 SUPERFAMILY SSF53335 3 167 2.19E-45 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_2195 ad1a08cb364ff8149ef8e6660199ed38 93 Gene3D G3DSA:2.30.30.90 17 73 4.9E-6 T 23-10-2018 IPR038157 Ferrous iron transporter, core domain VMUT_2195 ad1a08cb364ff8149ef8e6660199ed38 93 Pfam PF04023 FeoA domain 18 72 4.6E-5 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 VMUT_2195 ad1a08cb364ff8149ef8e6660199ed38 93 SUPERFAMILY SSF50037 12 73 2.2E-6 T 23-10-2018 IPR008988 Transcriptional repressor, C-terminal VMUT_0460 7373871db5b56e6940e307fc79e681a5 54 SUPERFAMILY SSF48662 7 54 1.83E-15 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily VMUT_0460 7373871db5b56e6940e307fc79e681a5 54 Gene3D G3DSA:1.10.1620.10 4 54 7.7E-16 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily VMUT_0460 7373871db5b56e6940e307fc79e681a5 54 Hamap MF_00629 50S ribosomal protein L39e [rpl39e]. 4 54 16.78 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_0460 7373871db5b56e6940e307fc79e681a5 54 Pfam PF00832 Ribosomal L39 protein 12 53 3.6E-18 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_1288 c12ab21f64e81bce1bea33360b8639bc 235 Gene3D G3DSA:3.30.70.270 120 234 9.7E-28 T 23-10-2018 VMUT_1288 c12ab21f64e81bce1bea33360b8639bc 235 ProDom PD313320 GTP III HYDROLASE CYCLOHYDROLASE RIBOFLAVIN BIOSYNTHESIS 3.5.4.- FAMILY MAGNESIUM GGDN 3 221 3.0E-27 T 23-10-2018 IPR007839 GTP cyclohydrolase III GO:0003933|GO:0009058 KEGG: 00740+3.5.4.29|MetaCyc: PWY-6167 VMUT_1288 c12ab21f64e81bce1bea33360b8639bc 235 Pfam PF05165 GTP cyclohydrolase III 4 233 1.8E-39 T 23-10-2018 IPR007839 GTP cyclohydrolase III GO:0003933|GO:0009058 KEGG: 00740+3.5.4.29|MetaCyc: PWY-6167 VMUT_1288 c12ab21f64e81bce1bea33360b8639bc 235 PIRSF PIRSF009265 1 235 2.5E-48 T 23-10-2018 IPR007839 GTP cyclohydrolase III GO:0003933|GO:0009058 KEGG: 00740+3.5.4.29|MetaCyc: PWY-6167 VMUT_1288 c12ab21f64e81bce1bea33360b8639bc 235 Gene3D G3DSA:3.30.70.1230 1 113 3.6E-33 T 23-10-2018 IPR029787 Nucleotide cyclase VMUT_1288 c12ab21f64e81bce1bea33360b8639bc 235 Hamap MF_00608 GTP cyclohydrolase III [gch3]. 4 233 28.05 T 23-10-2018 IPR007839 GTP cyclohydrolase III GO:0003933|GO:0009058 KEGG: 00740+3.5.4.29|MetaCyc: PWY-6167 VMUT_2029 9b45a5a571be6b1dde51727a844f7cb3 307 Pfam PF09376 NurA domain 50 268 3.4E-5 T 23-10-2018 IPR018977 NurA domain VMUT_2029 9b45a5a571be6b1dde51727a844f7cb3 307 SMART SM00933 48 268 5.5E-9 T 23-10-2018 IPR018977 NurA domain VMUT_2059 a7c76202a80a8394c9f45d63fc7987e8 891 TIGRFAM TIGR02390 RNA_pol_rpoA1: DNA-directed RNA polymerase subunit A' 18 883 0.0 T 23-10-2018 IPR012758 DNA-directed RNA polymerase subunit A' (Rpo1N) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_2059 a7c76202a80a8394c9f45d63fc7987e8 891 Gene3D G3DSA:1.20.120.1280 8 130 1.0E-30 T 23-10-2018 VMUT_2059 a7c76202a80a8394c9f45d63fc7987e8 891 Gene3D G3DSA:1.20.120.1280 243 293 1.8E-10 T 23-10-2018 VMUT_2059 a7c76202a80a8394c9f45d63fc7987e8 891 Gene3D G3DSA:1.10.274.100 503 656 3.3E-89 T 23-10-2018 VMUT_2059 a7c76202a80a8394c9f45d63fc7987e8 891 Gene3D G3DSA:3.30.1490.180 363 428 4.4E-81 T 23-10-2018 VMUT_2059 a7c76202a80a8394c9f45d63fc7987e8 891 SUPERFAMILY SSF64484 13 877 0.0 T 23-10-2018 VMUT_2059 a7c76202a80a8394c9f45d63fc7987e8 891 Gene3D G3DSA:2.20.25.410 841 888 1.8E-11 T 23-10-2018 VMUT_2059 a7c76202a80a8394c9f45d63fc7987e8 891 Pfam PF00623 RNA polymerase Rpb1, domain 2 330 497 1.6E-73 T 23-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_2059 a7c76202a80a8394c9f45d63fc7987e8 891 Pfam PF05000 RNA polymerase Rpb1, domain 4 690 795 2.3E-26 T 23-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_2059 a7c76202a80a8394c9f45d63fc7987e8 891 Gene3D G3DSA:1.10.132.30 657 803 3.3E-89 T 23-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_2059 a7c76202a80a8394c9f45d63fc7987e8 891 Pfam PF04997 RNA polymerase Rpb1, domain 1 18 328 9.3E-98 T 23-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_2059 a7c76202a80a8394c9f45d63fc7987e8 891 Pfam PF04998 RNA polymerase Rpb1, domain 5 802 867 7.8E-27 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_2059 a7c76202a80a8394c9f45d63fc7987e8 891 Pfam PF04983 RNA polymerase Rpb1, domain 3 500 662 4.0E-33 T 23-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_2059 a7c76202a80a8394c9f45d63fc7987e8 891 SMART SM00663 220 525 1.7E-198 T 23-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_2059 a7c76202a80a8394c9f45d63fc7987e8 891 Gene3D G3DSA:2.40.40.20 320 492 4.4E-81 T 23-10-2018 VMUT_0930 c43724fdecf04065d6e13309a7a2384f 281 Gene3D G3DSA:3.30.300.110 1 85 4.9E-18 T 23-10-2018 VMUT_0930 c43724fdecf04065d6e13309a7a2384f 281 SUPERFAMILY SSF53335 13 278 1.22E-53 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_0930 c43724fdecf04065d6e13309a7a2384f 281 Pfam PF02475 Met-10+ like-protein 31 226 4.0E-49 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 VMUT_0930 c43724fdecf04065d6e13309a7a2384f 281 Gene3D G3DSA:3.40.50.150 87 280 1.4E-38 T 23-10-2018 VMUT_1824 3bced671b69ed07a77f0d7e005f1119c 471 SMART SM00933 57 430 8.0E-16 T 23-10-2018 IPR018977 NurA domain VMUT_1824 3bced671b69ed07a77f0d7e005f1119c 471 Pfam PF09376 NurA domain 60 429 5.2E-19 T 23-10-2018 IPR018977 NurA domain VMUT_1157 2d1b95580cd67ba396b4891fdb010fab 402 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 10 391 5.8E-95 T 23-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 VMUT_1157 2d1b95580cd67ba396b4891fdb010fab 402 SUPERFAMILY SSF55031 199 308 4.36E-21 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VMUT_1157 2d1b95580cd67ba396b4891fdb010fab 402 PIRSF PIRSF001235 8 399 9.2E-119 T 23-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 VMUT_1157 2d1b95580cd67ba396b4891fdb010fab 402 Pfam PF01546 Peptidase family M20/M25/M40 75 392 8.2E-27 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 VMUT_1157 2d1b95580cd67ba396b4891fdb010fab 402 SUPERFAMILY SSF53187 3 396 5.14E-73 T 23-10-2018 VMUT_1157 2d1b95580cd67ba396b4891fdb010fab 402 Gene3D G3DSA:3.30.70.360 197 313 6.2E-111 T 23-10-2018 VMUT_1157 2d1b95580cd67ba396b4891fdb010fab 402 Gene3D G3DSA:3.40.630.10 15 389 6.2E-111 T 23-10-2018 VMUT_0420 900d24a660fc399c112c3daeaa5f0eee 349 Hamap MF_01409 UPF0219 protein . 3 347 56.805 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related VMUT_0420 900d24a660fc399c112c3daeaa5f0eee 349 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 220 301 2.0E-14 T 23-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 VMUT_0420 900d24a660fc399c112c3daeaa5f0eee 349 Pfam PF00108 Thiolase, N-terminal domain 49 143 2.7E-8 T 23-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 VMUT_0420 900d24a660fc399c112c3daeaa5f0eee 349 TIGRFAM TIGR00748 HMG_CoA_syn_Arc: putative hydroxymethylglutaryl-CoA synthase 4 346 3.2E-151 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related VMUT_0420 900d24a660fc399c112c3daeaa5f0eee 349 Gene3D G3DSA:3.40.47.10 2 347 8.4E-75 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_0420 900d24a660fc399c112c3daeaa5f0eee 349 SUPERFAMILY SSF53901 3 308 5.9E-47 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_0117 2e18b02176201525d3da49f57d5d78c6 454 SUPERFAMILY SSF103473 1 430 9.42E-67 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_0117 2e18b02176201525d3da49f57d5d78c6 454 Pfam PF00083 Sugar (and other) transporter 2 433 1.6E-65 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VMUT_0117 2e18b02176201525d3da49f57d5d78c6 454 Gene3D G3DSA:1.20.1250.20 1 434 9.0E-89 T 23-10-2018 VMUT_0117 2e18b02176201525d3da49f57d5d78c6 454 PRINTS PR00171 Sugar transporter signature 360 372 3.0E-6 T 23-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 VMUT_0117 2e18b02176201525d3da49f57d5d78c6 454 PRINTS PR00171 Sugar transporter signature 3 13 3.0E-6 T 23-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 VMUT_0117 2e18b02176201525d3da49f57d5d78c6 454 PRINTS PR00171 Sugar transporter signature 88 107 3.0E-6 T 23-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 VMUT_0221 662d3d13e3f9b59657fe2890e227bb9a 378 Pfam PF12704 MacB-like periplasmic core domain 14 206 1.4E-12 T 23-10-2018 IPR025857 MacB-like periplasmic core domain VMUT_0221 662d3d13e3f9b59657fe2890e227bb9a 378 Pfam PF02687 FtsX-like permease family 277 369 8.2E-11 T 23-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 VMUT_1399 7828f44b9cb4dc244845fb3339462b21 91 Gene3D G3DSA:3.30.70.240 1 66 2.2E-16 T 23-10-2018 VMUT_1399 7828f44b9cb4dc244845fb3339462b21 91 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 81 2.3E-13 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 VMUT_1399 7828f44b9cb4dc244845fb3339462b21 91 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 85 13.76 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 VMUT_1399 7828f44b9cb4dc244845fb3339462b21 91 Pfam PF09827 CRISPR associated protein Cas2 1 68 2.7E-12 T 23-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 VMUT_1399 7828f44b9cb4dc244845fb3339462b21 91 SUPERFAMILY SSF143430 1 78 5.1E-14 T 23-10-2018 VMUT_1478 d4909c2be80fe1fba72125f921f8d64c 158 SUPERFAMILY SSF158568 9 155 8.76E-17 T 23-10-2018 IPR023101 AF1862-like domain superfamily VMUT_1478 d4909c2be80fe1fba72125f921f8d64c 158 Pfam PF09701 CRISPR-associated protein (Cas_Cmr5) 13 154 5.0E-7 T 23-10-2018 IPR010160 CRISPR-associated protein, Cmr5 VMUT_1478 d4909c2be80fe1fba72125f921f8d64c 158 Gene3D G3DSA:1.10.520.30 3 158 1.3E-9 T 23-10-2018 IPR023101 AF1862-like domain superfamily VMUT_1478 d4909c2be80fe1fba72125f921f8d64c 158 TIGRFAM TIGR01881 cas_Cmr5: CRISPR type III-B/RAMP module-associated protein Cmr5 10 156 1.9E-14 T 23-10-2018 IPR010160 CRISPR-associated protein, Cmr5 VMUT_0738 63a38794d773b1389505794089068aa1 314 ProSitePatterns PS00770 Aminotransferases class-IV signature. 200 229 - T 23-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 VMUT_0738 63a38794d773b1389505794089068aa1 314 Gene3D G3DSA:3.30.470.10 7 140 1.1E-38 T 23-10-2018 VMUT_0738 63a38794d773b1389505794089068aa1 314 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 18 313 7.3E-118 T 23-10-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 VMUT_0738 63a38794d773b1389505794089068aa1 314 Gene3D G3DSA:3.20.10.10 141 302 4.4E-53 T 23-10-2018 VMUT_0738 63a38794d773b1389505794089068aa1 314 SUPERFAMILY SSF56752 15 310 6.28E-97 T 23-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 VMUT_0738 63a38794d773b1389505794089068aa1 314 Pfam PF01063 Amino-transferase class IV 44 274 1.1E-43 T 23-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 VMUT_0033 d6c4526260d11571e0b6adea1f10cfa1 355 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 256 346 9.4E-19 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II VMUT_0033 d6c4526260d11571e0b6adea1f10cfa1 355 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 187 2.0E-63 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 VMUT_0033 d6c4526260d11571e0b6adea1f10cfa1 355 SUPERFAMILY SSF52922 253 352 3.01E-21 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VMUT_0033 d6c4526260d11571e0b6adea1f10cfa1 355 Gene3D G3DSA:3.40.50.920 245 354 6.8E-24 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VMUT_0033 d6c4526260d11571e0b6adea1f10cfa1 355 Gene3D G3DSA:3.40.50.970 1 191 1.4E-76 T 23-10-2018 VMUT_0033 d6c4526260d11571e0b6adea1f10cfa1 355 SUPERFAMILY SSF52518 4 236 2.83E-67 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold VMUT_1816 1576c3a184ff8bfff0b76a32e29b5064 388 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 304 315 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_1816 1576c3a184ff8bfff0b76a32e29b5064 388 SUPERFAMILY SSF100950 50 286 5.86E-42 T 23-10-2018 IPR037171 NagB/RpiA transferase-like VMUT_1816 1576c3a184ff8bfff0b76a32e29b5064 388 Pfam PF02589 LUD domain 57 285 4.5E-46 T 23-10-2018 IPR003741 LUD domain VMUT_1816 1576c3a184ff8bfff0b76a32e29b5064 388 Gene3D G3DSA:3.40.50.10420 109 285 3.3E-23 T 23-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily VMUT_1816 1576c3a184ff8bfff0b76a32e29b5064 388 Gene3D G3DSA:1.10.1060.10 286 388 1.3E-7 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VMUT_1816 1576c3a184ff8bfff0b76a32e29b5064 388 Pfam PF13183 4Fe-4S dicluster domain 303 368 1.6E-9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_1816 1576c3a184ff8bfff0b76a32e29b5064 388 SUPERFAMILY SSF46548 277 385 4.71E-18 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VMUT_0329 666e24280082834dab28abfb0635c7f4 190 SUPERFAMILY SSF103473 2 186 1.44E-9 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_0329 666e24280082834dab28abfb0635c7f4 190 Gene3D G3DSA:1.20.1250.20 1 190 2.1E-6 T 23-10-2018 VMUT_1476 cc5250a77d2ed1a7ea3dfc2ecbc3e535 1068 TIGRFAM TIGR02577 cas_TM1794_Cmr2: CRISPR-associated protein Cas10/Cmr2, subtype III-B 542 911 8.1E-28 T 23-10-2018 IPR013407 CRISPR-associated protein Cmr2 VMUT_1476 cc5250a77d2ed1a7ea3dfc2ecbc3e535 1068 Pfam PF12469 CRISPR-associated protein 210 344 2.1E-26 T 23-10-2018 IPR024615 CRISPR-associated protein Cmr2, N-terminal VMUT_1476 cc5250a77d2ed1a7ea3dfc2ecbc3e535 1068 Gene3D G3DSA:3.30.70.2220 176 330 5.8E-28 T 23-10-2018 IPR038242 Cmr2, N-terminal domain superfamily VMUT_0316 769586ae153dab0b8d69bc46b81347b1 393 SUPERFAMILY SSF53383 5 390 4.12E-75 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VMUT_0316 769586ae153dab0b8d69bc46b81347b1 393 Gene3D G3DSA:3.40.640.10 29 301 3.0E-82 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VMUT_0316 769586ae153dab0b8d69bc46b81347b1 393 Pfam PF00266 Aminotransferase class-V 18 381 1.4E-33 T 23-10-2018 IPR000192 Aminotransferase class V domain VMUT_0316 769586ae153dab0b8d69bc46b81347b1 393 Gene3D G3DSA:3.90.1150.10 14 381 3.0E-82 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VMUT_1945 8a9cfad711d30bdbe00bead40fef9d7d 351 SUPERFAMILY SSF56059 114 351 6.25E-75 T 23-10-2018 VMUT_1945 8a9cfad711d30bdbe00bead40fef9d7d 351 Gene3D G3DSA:3.30.470.20 97 350 5.5E-90 T 23-10-2018 VMUT_1945 8a9cfad711d30bdbe00bead40fef9d7d 351 SUPERFAMILY SSF52440 4 108 4.8E-40 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily VMUT_1945 8a9cfad711d30bdbe00bead40fef9d7d 351 Gene3D G3DSA:3.40.50.20 1 96 8.3E-34 T 23-10-2018 VMUT_1945 8a9cfad711d30bdbe00bead40fef9d7d 351 Pfam PF06849 Protein of unknown function (DUF1246) 6 130 5.6E-47 T 23-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 VMUT_1945 8a9cfad711d30bdbe00bead40fef9d7d 351 Gene3D G3DSA:3.30.1490.20 127 192 5.5E-90 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VMUT_1945 8a9cfad711d30bdbe00bead40fef9d7d 351 PIRSF PIRSF004602 1 351 2.0E-145 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 VMUT_1945 8a9cfad711d30bdbe00bead40fef9d7d 351 Pfam PF06973 Domain of unknown function (DUF1297) 164 351 1.9E-80 T 23-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 VMUT_0624 3306fbe4faa40b7032e72a4ca3f5c5e6 330 PRINTS PR00959 Mevalonate kinase family signature 6 30 9.7E-28 T 23-10-2018 VMUT_0624 3306fbe4faa40b7032e72a4ca3f5c5e6 330 PRINTS PR00959 Mevalonate kinase family signature 282 299 9.7E-28 T 23-10-2018 VMUT_0624 3306fbe4faa40b7032e72a4ca3f5c5e6 330 PRINTS PR00959 Mevalonate kinase family signature 149 168 9.7E-28 T 23-10-2018 VMUT_0624 3306fbe4faa40b7032e72a4ca3f5c5e6 330 PRINTS PR00959 Mevalonate kinase family signature 106 128 9.7E-28 T 23-10-2018 VMUT_0624 3306fbe4faa40b7032e72a4ca3f5c5e6 330 SUPERFAMILY SSF55060 189 327 5.58E-31 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily VMUT_0624 3306fbe4faa40b7032e72a4ca3f5c5e6 330 Pfam PF08544 GHMP kinases C terminal 236 308 1.5E-13 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain VMUT_0624 3306fbe4faa40b7032e72a4ca3f5c5e6 330 Gene3D G3DSA:3.30.70.890 192 315 1.3E-35 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily VMUT_0624 3306fbe4faa40b7032e72a4ca3f5c5e6 330 SUPERFAMILY SSF54211 1 174 9.87E-43 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VMUT_0624 3306fbe4faa40b7032e72a4ca3f5c5e6 330 Hamap MF_00217 Mevalonate kinase [mvk]. 2 324 58.845 T 23-10-2018 IPR022937 Mevalonate kinase, archaeal GO:0004496 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922 VMUT_0624 3306fbe4faa40b7032e72a4ca3f5c5e6 330 Pfam PF00288 GHMP kinases N terminal domain 101 168 2.5E-14 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 VMUT_0624 3306fbe4faa40b7032e72a4ca3f5c5e6 330 Gene3D G3DSA:3.30.230.10 1 187 9.3E-48 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup VMUT_0624 3306fbe4faa40b7032e72a4ca3f5c5e6 330 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 6 297 4.4E-80 T 23-10-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 VMUT_0624 3306fbe4faa40b7032e72a4ca3f5c5e6 330 Pfam PF10509 Galactokinase galactose-binding signature 3 38 1.6E-4 T 23-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 VMUT_0385 0f62689e372106b436ec742e948677e1 223 TIGRFAM TIGR03724 arch_bud32: Kae1-associated kinase Bud32 6 220 7.7E-58 T 23-10-2018 IPR022495 Serine/threonine-protein kinase Bud32 GO:0004674 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 VMUT_0385 0f62689e372106b436ec742e948677e1 223 Gene3D G3DSA:1.10.510.10 94 222 9.5E-19 T 23-10-2018 VMUT_0385 0f62689e372106b436ec742e948677e1 223 SUPERFAMILY SSF56112 4 154 1.35E-25 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily VMUT_0385 0f62689e372106b436ec742e948677e1 223 Gene3D G3DSA:3.30.200.20 11 83 9.8E-26 T 23-10-2018 VMUT_0385 0f62689e372106b436ec742e948677e1 223 Pfam PF01163 RIO1 family 41 145 1.3E-10 T 23-10-2018 VMUT_0217 309ab0239a3b6eb3a91ab7235d2b1441 92 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 1 92 3.2E-21 T 23-10-2018 IPR010038 MoaD, archaeal-type VMUT_0217 309ab0239a3b6eb3a91ab7235d2b1441 92 SUPERFAMILY SSF54285 1 92 1.14E-19 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp VMUT_0217 309ab0239a3b6eb3a91ab7235d2b1441 92 Pfam PF02597 ThiS family 3 92 1.4E-14 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 VMUT_0217 309ab0239a3b6eb3a91ab7235d2b1441 92 Gene3D G3DSA:3.10.20.30 1 92 1.1E-23 T 23-10-2018 IPR012675 Beta-grasp domain superfamily VMUT_2175 4c081b62c651f88d4635d94be025cf0b 367 Pfam PF04055 Radical SAM superfamily 90 270 6.0E-19 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_2175 4c081b62c651f88d4635d94be025cf0b 367 Pfam PF08608 Wyosine base formation 280 345 4.0E-18 T 23-10-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 VMUT_2175 4c081b62c651f88d4635d94be025cf0b 367 TIGRFAM TIGR03972 rSAM_TYW1: wyosine biosynthesis protein TYW1 35 344 4.0E-104 T 23-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 VMUT_2175 4c081b62c651f88d4635d94be025cf0b 367 Gene3D G3DSA:3.20.20.70 27 354 3.6E-97 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_2175 4c081b62c651f88d4635d94be025cf0b 367 Hamap MF_01921 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase [taw1]. 32 345 44.575 T 23-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 VMUT_2175 4c081b62c651f88d4635d94be025cf0b 367 SUPERFAMILY SSF102114 87 303 1.7E-19 T 23-10-2018 VMUT_2056 bc0792a91b40b9694c53b3a5adc8bb81 643 PRINTS PR01038 Arginyl-tRNA synthetase signature 156 169 2.9E-12 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 VMUT_2056 bc0792a91b40b9694c53b3a5adc8bb81 643 PRINTS PR01038 Arginyl-tRNA synthetase signature 117 132 2.9E-12 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 VMUT_2056 bc0792a91b40b9694c53b3a5adc8bb81 643 PRINTS PR01038 Arginyl-tRNA synthetase signature 132 148 2.9E-12 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 VMUT_2056 bc0792a91b40b9694c53b3a5adc8bb81 643 SUPERFAMILY SSF47323 524 643 2.49E-25 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_2056 bc0792a91b40b9694c53b3a5adc8bb81 643 Gene3D G3DSA:1.10.730.10 529 643 5.3E-26 T 23-10-2018 VMUT_2056 bc0792a91b40b9694c53b3a5adc8bb81 643 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 272 643 1.8E-86 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 VMUT_2056 bc0792a91b40b9694c53b3a5adc8bb81 643 SMART SM00836 529 643 1.5E-27 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 VMUT_2056 bc0792a91b40b9694c53b3a5adc8bb81 643 Pfam PF00750 tRNA synthetases class I (R) 272 515 1.8E-25 T 23-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 VMUT_2056 bc0792a91b40b9694c53b3a5adc8bb81 643 Pfam PF00750 tRNA synthetases class I (R) 117 169 3.5E-9 T 23-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 VMUT_2056 bc0792a91b40b9694c53b3a5adc8bb81 643 Pfam PF05746 DALR anticodon binding domain 529 643 2.6E-23 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 VMUT_2056 bc0792a91b40b9694c53b3a5adc8bb81 643 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 127 136 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_2056 bc0792a91b40b9694c53b3a5adc8bb81 643 Hamap MF_00123 Arginine--tRNA ligase [argS]. 6 643 22.137 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 VMUT_2056 bc0792a91b40b9694c53b3a5adc8bb81 643 SUPERFAMILY SSF52374 116 520 4.07E-73 T 23-10-2018 VMUT_0418 d8208862ce455e3da7a88c564fbeda7b 237 SUPERFAMILY SSF51161 12 218 3.76E-43 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily VMUT_0418 d8208862ce455e3da7a88c564fbeda7b 237 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 176 204 - T 23-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 VMUT_0418 d8208862ce455e3da7a88c564fbeda7b 237 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 106 134 - T 23-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 VMUT_0418 d8208862ce455e3da7a88c564fbeda7b 237 Gene3D G3DSA:2.160.10.10 2 218 5.9E-58 T 23-10-2018 VMUT_0418 d8208862ce455e3da7a88c564fbeda7b 237 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 168 202 1.6E-11 T 23-10-2018 IPR001451 Hexapeptide repeat VMUT_0418 d8208862ce455e3da7a88c564fbeda7b 237 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 4 41 2.0E-4 T 23-10-2018 IPR001451 Hexapeptide repeat VMUT_0418 d8208862ce455e3da7a88c564fbeda7b 237 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 67 101 1.5E-8 T 23-10-2018 IPR001451 Hexapeptide repeat VMUT_0418 d8208862ce455e3da7a88c564fbeda7b 237 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 121 156 1.8E-8 T 23-10-2018 IPR001451 Hexapeptide repeat VMUT_1083 f8fadfb6af718623ccec3cbd543f9cb5 388 Pfam PF00534 Glycosyl transferases group 1 215 356 3.4E-16 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 VMUT_1083 f8fadfb6af718623ccec3cbd543f9cb5 388 Pfam PF13439 Glycosyltransferase Family 4 18 203 3.1E-9 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 VMUT_1083 f8fadfb6af718623ccec3cbd543f9cb5 388 Gene3D G3DSA:3.40.50.2000 3 211 1.6E-12 T 23-10-2018 VMUT_1083 f8fadfb6af718623ccec3cbd543f9cb5 388 SUPERFAMILY SSF53756 1 386 9.16E-51 T 23-10-2018 VMUT_1083 f8fadfb6af718623ccec3cbd543f9cb5 388 Gene3D G3DSA:3.40.50.2000 212 371 1.3E-25 T 23-10-2018 VMUT_1767 97df57d7e9ff1271efb8c13f3ed252c6 278 Hamap MF_01328_A 50S ribosomal protein L4 [rplD]. 21 274 42.923 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 VMUT_1767 97df57d7e9ff1271efb8c13f3ed252c6 278 Gene3D G3DSA:3.40.1370.10 18 276 1.7E-88 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 VMUT_1767 97df57d7e9ff1271efb8c13f3ed252c6 278 Pfam PF00573 Ribosomal protein L4/L1 family 35 273 2.2E-40 T 23-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 VMUT_1767 97df57d7e9ff1271efb8c13f3ed252c6 278 TIGRFAM TIGR03672 rpl4p_arch: 50S ribosomal protein uL4 22 273 2.1E-105 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 VMUT_1767 97df57d7e9ff1271efb8c13f3ed252c6 278 SUPERFAMILY SSF52166 21 272 2.22E-64 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 VMUT_1767 97df57d7e9ff1271efb8c13f3ed252c6 278 ProSitePatterns PS00939 Ribosomal protein L1e signature. 126 152 - T 23-10-2018 IPR013000 Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1291 469b7f46221aa8519136f5b8d42a154e 332 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VMUT_1291 469b7f46221aa8519136f5b8d42a154e 332 Pfam PF13732 Domain of unknown function (DUF4162) 218 305 1.0E-13 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 VMUT_1291 469b7f46221aa8519136f5b8d42a154e 332 Pfam PF00005 ABC transporter 21 163 3.0E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_1291 469b7f46221aa8519136f5b8d42a154e 332 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 307 1.4E-124 T 23-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 VMUT_1291 469b7f46221aa8519136f5b8d42a154e 332 Gene3D G3DSA:3.40.50.300 1 235 9.2E-71 T 23-10-2018 VMUT_1291 469b7f46221aa8519136f5b8d42a154e 332 SUPERFAMILY SSF52540 4 228 1.52E-67 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1291 469b7f46221aa8519136f5b8d42a154e 332 SMART SM00382 29 215 1.2E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0760 e83e893e43fa6fb8f8ac00287855cf09 199 Pfam PF00203 Ribosomal protein S19 98 182 1.9E-28 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0760 e83e893e43fa6fb8f8ac00287855cf09 199 PRINTS PR00975 Ribosomal protein S19 family signature 132 151 2.0E-12 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0760 e83e893e43fa6fb8f8ac00287855cf09 199 PRINTS PR00975 Ribosomal protein S19 family signature 152 164 2.0E-12 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0760 e83e893e43fa6fb8f8ac00287855cf09 199 PRINTS PR00975 Ribosomal protein S19 family signature 164 179 2.0E-12 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0760 e83e893e43fa6fb8f8ac00287855cf09 199 Gene3D G3DSA:3.30.860.20 61 197 2.7E-46 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0760 e83e893e43fa6fb8f8ac00287855cf09 199 TIGRFAM TIGR01025 uS19_arch: ribosomal protein uS19 68 198 3.3E-51 T 23-10-2018 IPR005713 Ribosomal protein S19A/S15e GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0760 e83e893e43fa6fb8f8ac00287855cf09 199 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 96 188 22.19 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0760 e83e893e43fa6fb8f8ac00287855cf09 199 SUPERFAMILY SSF54570 113 183 6.54E-25 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0760 e83e893e43fa6fb8f8ac00287855cf09 199 ProSitePatterns PS00323 Ribosomal protein S19 signature. 152 176 - T 23-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_2085 2978b693c20216782cfceee3c75bd7fb 226 SMART SM00654 9 205 4.1E-57 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 VMUT_2085 2978b693c20216782cfceee3c75bd7fb 226 TIGRFAM TIGR00323 eIF-6: putative translation initiation factor eIF-6 14 224 2.5E-54 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 VMUT_2085 2978b693c20216782cfceee3c75bd7fb 226 PIRSF PIRSF006413 7 226 1.3E-67 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 VMUT_2085 2978b693c20216782cfceee3c75bd7fb 226 SUPERFAMILY SSF55909 10 223 9.02E-59 T 23-10-2018 VMUT_2085 2978b693c20216782cfceee3c75bd7fb 226 Pfam PF01912 eIF-6 family 11 204 6.3E-60 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 VMUT_2085 2978b693c20216782cfceee3c75bd7fb 226 Gene3D G3DSA:3.75.10.10 9 225 1.5E-65 T 23-10-2018 VMUT_2085 2978b693c20216782cfceee3c75bd7fb 226 Hamap MF_00032 Translation initiation factor 6 [eif6]. 1 226 75.45 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 VMUT_0001 7af50db92d5f33788cf8296a15f84558 355 SUPERFAMILY SSF56024 43 174 1.3E-23 T 23-10-2018 VMUT_0001 7af50db92d5f33788cf8296a15f84558 355 SUPERFAMILY SSF56024 254 307 5.83E-10 T 23-10-2018 VMUT_0001 7af50db92d5f33788cf8296a15f84558 355 Gene3D G3DSA:3.30.870.10 249 309 2.6E-8 T 23-10-2018 VMUT_0001 7af50db92d5f33788cf8296a15f84558 355 Gene3D G3DSA:3.30.870.10 15 174 9.7E-26 T 23-10-2018 VMUT_0001 7af50db92d5f33788cf8296a15f84558 355 SMART SM00155 250 276 66.0 T 23-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 VMUT_0001 7af50db92d5f33788cf8296a15f84558 355 SMART SM00155 117 144 0.1 T 23-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 VMUT_0001 7af50db92d5f33788cf8296a15f84558 355 Pfam PF13091 PLD-like domain 46 164 6.5E-15 T 23-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 VMUT_0001 7af50db92d5f33788cf8296a15f84558 355 Pfam PF13091 PLD-like domain 256 302 7.1E-9 T 23-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 VMUT_1854 840b48cccbda45c80746f9468dfa90ac 259 Gene3D G3DSA:3.40.50.1220 22 246 7.8E-84 T 23-10-2018 VMUT_1854 840b48cccbda45c80746f9468dfa90ac 259 SUPERFAMILY SSF52467 7 252 2.45E-85 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily VMUT_1854 840b48cccbda45c80746f9468dfa90ac 259 Hamap MF_01968 NAD-dependent protein deacetylase [cobB]. 15 249 62.314 T 23-10-2018 IPR028628 Sirtuin, class U GO:0034979|GO:0051287 VMUT_1854 840b48cccbda45c80746f9468dfa90ac 259 Pfam PF02146 Sir2 family 31 204 1.2E-50 T 23-10-2018 IPR003000 Sirtuin family GO:0070403 VMUT_1854 840b48cccbda45c80746f9468dfa90ac 259 Gene3D G3DSA:3.30.1600.10 40 176 7.8E-84 T 23-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily VMUT_2340 87f38c4eb7ce65fad664e6770d30d9d4 97 Pfam PF08221 RNA polymerase III subunit RPC82 helix-turn-helix domain 33 76 8.1E-7 T 23-10-2018 IPR013197 RNA polymerase III subunit RPC82-related, helix-turn-helix Reactome: R-HSA-1834949|Reactome: R-HSA-73780|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071 VMUT_2340 87f38c4eb7ce65fad664e6770d30d9d4 97 Gene3D G3DSA:1.10.10.10 31 95 6.6E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_2340 87f38c4eb7ce65fad664e6770d30d9d4 97 SUPERFAMILY SSF46785 33 93 8.41E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_1737 9268119ca3e02238c9e736d330ea13f5 392 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 109 127 3.5E-10 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 VMUT_1737 9268119ca3e02238c9e736d330ea13f5 392 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 88 108 3.5E-10 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 VMUT_1737 9268119ca3e02238c9e736d330ea13f5 392 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 152 170 3.5E-10 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 VMUT_1737 9268119ca3e02238c9e736d330ea13f5 392 Pfam PF01926 50S ribosome-binding GTPase 87 189 4.5E-10 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 VMUT_1737 9268119ca3e02238c9e736d330ea13f5 392 Pfam PF02824 TGS domain 316 389 5.2E-17 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 VMUT_1737 9268119ca3e02238c9e736d330ea13f5 392 Gene3D G3DSA:3.10.20.30 311 391 5.1E-20 T 23-10-2018 IPR012675 Beta-grasp domain superfamily VMUT_1737 9268119ca3e02238c9e736d330ea13f5 392 SUPERFAMILY SSF81271 313 390 1.44E-18 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 VMUT_1737 9268119ca3e02238c9e736d330ea13f5 392 SUPERFAMILY SSF52540 87 322 6.39E-25 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1737 9268119ca3e02238c9e736d330ea13f5 392 Pfam PF16897 C-terminal region of MMR_HSR1 domain 208 299 1.1E-14 T 23-10-2018 IPR031662 GTP binding protein, second domain VMUT_2017 2941138633b23c088637b60cf45bb2f3 241 SUPERFAMILY SSF100950 6 221 3.21E-30 T 23-10-2018 IPR037171 NagB/RpiA transferase-like VMUT_2017 2941138633b23c088637b60cf45bb2f3 241 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 7 202 4.1E-30 T 23-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase VMUT_2017 2941138633b23c088637b60cf45bb2f3 241 Gene3D G3DSA:3.40.50.10420 39 209 5.0E-8 T 23-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily VMUT_2076 25fb69ecc7b3e457d5a0b93e55c14745 81 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 13 37 - T 23-10-2018 IPR001455 TusA-like domain VMUT_2076 25fb69ecc7b3e457d5a0b93e55c14745 81 Pfam PF01206 Sulfurtransferase TusA 12 80 2.2E-23 T 23-10-2018 IPR001455 TusA-like domain VMUT_2076 25fb69ecc7b3e457d5a0b93e55c14745 81 Gene3D G3DSA:3.30.110.40 9 80 4.8E-24 T 23-10-2018 IPR036868 TusA-like domain superfamily VMUT_2076 25fb69ecc7b3e457d5a0b93e55c14745 81 SUPERFAMILY SSF64307 9 80 9.55E-24 T 23-10-2018 IPR036868 TusA-like domain superfamily VMUT_0886 b14bf08536ef163541abe7a7c17b9c99 153 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 3 124 5.9E-12 T 23-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VMUT_0886 b14bf08536ef163541abe7a7c17b9c99 153 TIGRFAM TIGR01506 ribC_arch: riboflavin synthase 5 151 4.7E-53 T 23-10-2018 IPR006399 Riboflavin synthase, archaeal GO:0004746|GO:0009231 KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VMUT_0886 b14bf08536ef163541abe7a7c17b9c99 153 SUPERFAMILY SSF52121 3 129 2.88E-22 T 23-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VMUT_0886 b14bf08536ef163541abe7a7c17b9c99 153 Gene3D G3DSA:3.40.50.960 1 153 3.4E-52 T 23-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VMUT_0265 eaea2fdd0f909d576ee740df7eb88167 228 Pfam PF03587 EMG1/NEP1 methyltransferase 6 221 9.1E-40 T 23-10-2018 IPR005304 Ribosomal biogenesis, methyltransferase, EMG1/NEP1 GO:0008168 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 VMUT_0265 eaea2fdd0f909d576ee740df7eb88167 228 SUPERFAMILY SSF75217 3 225 3.14E-49 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases VMUT_0265 eaea2fdd0f909d576ee740df7eb88167 228 Hamap MF_00554 Ribosomal RNA small subunit methyltransferase Nep1 [nep1]. 4 223 29.224 T 23-10-2018 IPR023503 Ribosome biogenesis methyltransferase NEP1, archaea GO:0008168 VMUT_0265 eaea2fdd0f909d576ee740df7eb88167 228 Gene3D G3DSA:3.40.1280.10 3 224 1.3E-62 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal VMUT_0413 96475bd1d3de52a9c605a854864b414a 95 SUPERFAMILY SSF54285 2 95 1.63E-17 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp VMUT_0413 96475bd1d3de52a9c605a854864b414a 95 Pfam PF02597 ThiS family 5 95 2.2E-12 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 VMUT_0413 96475bd1d3de52a9c605a854864b414a 95 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 3 95 1.1E-18 T 23-10-2018 IPR010038 MoaD, archaeal-type VMUT_0413 96475bd1d3de52a9c605a854864b414a 95 Gene3D G3DSA:3.10.20.30 1 95 1.0E-22 T 23-10-2018 IPR012675 Beta-grasp domain superfamily VMUT_1145 56ad8772dd8676aedae5a83eedee7046 72 Gene3D G3DSA:3.40.630.30 1 69 2.7E-8 T 23-10-2018 VMUT_1145 56ad8772dd8676aedae5a83eedee7046 72 Pfam PF00583 Acetyltransferase (GNAT) family 3 62 3.8E-7 T 23-10-2018 IPR000182 GNAT domain VMUT_1145 56ad8772dd8676aedae5a83eedee7046 72 SUPERFAMILY SSF55729 2 64 2.48E-9 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase VMUT_2216 8f88b60acbd9b1bcdebed47e99a27ca6 562 Gene3D G3DSA:1.10.3720.10 284 548 1.8E-27 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_2216 8f88b60acbd9b1bcdebed47e99a27ca6 562 SUPERFAMILY SSF161098 288 562 5.51E-34 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_2216 8f88b60acbd9b1bcdebed47e99a27ca6 562 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 269 3.9E-12 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VMUT_2216 8f88b60acbd9b1bcdebed47e99a27ca6 562 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 382 553 9.0E-9 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VMUT_2216 8f88b60acbd9b1bcdebed47e99a27ca6 562 SUPERFAMILY SSF161098 49 261 2.49E-39 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_2216 8f88b60acbd9b1bcdebed47e99a27ca6 562 Gene3D G3DSA:1.10.3720.10 39 275 5.7E-40 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_0756 4fe2f21f758b0d732126cb43de7ada0c 653 Pfam PF00326 Prolyl oligopeptidase family 425 639 3.9E-56 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 VMUT_0756 4fe2f21f758b0d732126cb43de7ada0c 653 SUPERFAMILY SSF82171 16 372 8.76E-21 T 23-10-2018 VMUT_0756 4fe2f21f758b0d732126cb43de7ada0c 653 Gene3D G3DSA:3.40.50.1820 382 643 7.9E-71 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold VMUT_0756 4fe2f21f758b0d732126cb43de7ada0c 653 SUPERFAMILY SSF53474 379 638 1.43E-69 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold VMUT_0756 4fe2f21f758b0d732126cb43de7ada0c 653 Gene3D G3DSA:2.120.10.30 146 377 8.1E-13 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like VMUT_1226 2269e612750e7787d3ad91d893515515 253 Gene3D G3DSA:1.20.120.1220 6 141 3.7E-22 T 23-10-2018 VMUT_1226 2269e612750e7787d3ad91d893515515 253 Pfam PF01478 Type IV leader peptidase family 14 126 3.4E-9 T 23-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 VMUT_0539 3a940d5825926acab25d5bad1b55daa9 331 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 4 312 6.2E-95 T 23-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 VMUT_0539 3a940d5825926acab25d5bad1b55daa9 331 Gene3D G3DSA:3.40.718.10 1 315 9.8E-113 T 23-10-2018 VMUT_0539 3a940d5825926acab25d5bad1b55daa9 331 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 36 309 4.7E-93 T 23-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 VMUT_0539 3a940d5825926acab25d5bad1b55daa9 331 SUPERFAMILY SSF53659 3 316 5.0E-93 T 23-10-2018 VMUT_0745 9dd1d74371300dd2499683f8061897a8 51 Hamap MF_00788 50S ribosomal protein L40e [rpl40e]. 7 51 16.179 T 23-10-2018 IPR023657 Ribosomal protein L40e, archaeal GO:0003735|GO:0005840|GO:0006412 VMUT_0745 9dd1d74371300dd2499683f8061897a8 51 ProSitePatterns PS01358 Zinc finger RanBP2-type signature. 20 39 - T 23-10-2018 IPR001876 Zinc finger, RanBP2-type VMUT_0745 9dd1d74371300dd2499683f8061897a8 51 Pfam PF01020 Ribosomal L40e family 10 48 1.6E-7 T 23-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 VMUT_0745 9dd1d74371300dd2499683f8061897a8 51 SMART SM01377 3 51 2.9E-21 T 23-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 VMUT_0745 9dd1d74371300dd2499683f8061897a8 51 Gene3D G3DSA:2.20.28.70 1 51 1.1E-23 T 23-10-2018 IPR038587 Ribosomal protein L40e superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 VMUT_0745 9dd1d74371300dd2499683f8061897a8 51 SUPERFAMILY SSF57829 1 48 4.21E-18 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 VMUT_1527 edc21463c3640987d6abeace56545be3 491 SMART SM00917 344 477 1.2E-27 T 23-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 VMUT_1527 edc21463c3640987d6abeace56545be3 491 Pfam PF00682 HMGL-like 3 221 2.0E-41 T 23-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 VMUT_1527 edc21463c3640987d6abeace56545be3 491 Gene3D G3DSA:3.20.20.70 1 295 7.0E-94 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_1527 edc21463c3640987d6abeace56545be3 491 SUPERFAMILY SSF51569 2 262 6.41E-69 T 23-10-2018 VMUT_1527 edc21463c3640987d6abeace56545be3 491 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 3 483 8.2E-167 T 23-10-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 VMUT_1527 edc21463c3640987d6abeace56545be3 491 SUPERFAMILY SSF110921 371 476 9.94E-15 T 23-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 VMUT_1527 edc21463c3640987d6abeace56545be3 491 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 171 184 - T 23-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 VMUT_1527 edc21463c3640987d6abeace56545be3 491 Pfam PF08502 LeuA allosteric (dimerisation) domain 347 477 1.3E-21 T 23-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 VMUT_0021 c003699271ad87b89b1a511bfa1678fd 867 Gene3D G3DSA:1.10.439.10 63 207 1.6E-26 T 23-10-2018 IPR023343 Penicillin amidase type, domain 1 GO:0016811 VMUT_0021 c003699271ad87b89b1a511bfa1678fd 867 Pfam PF01804 Penicillin amidase 71 846 2.0E-157 T 23-10-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 VMUT_0021 c003699271ad87b89b1a511bfa1678fd 867 Gene3D G3DSA:1.10.1400.10 608 761 4.7E-111 T 23-10-2018 VMUT_0021 c003699271ad87b89b1a511bfa1678fd 867 Gene3D G3DSA:2.30.120.10 391 457 4.7E-111 T 23-10-2018 VMUT_0021 c003699271ad87b89b1a511bfa1678fd 867 PIRSF PIRSF001227 25 857 2.6E-166 T 23-10-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 VMUT_0021 c003699271ad87b89b1a511bfa1678fd 867 SUPERFAMILY SSF56235 68 848 3.86E-175 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VMUT_0021 c003699271ad87b89b1a511bfa1678fd 867 Gene3D G3DSA:3.60.20.10 322 841 4.7E-111 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VMUT_1677 235beb1d3cbb734e4542a78a77d1c6de 487 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 396 417 2.3E-69 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 VMUT_1677 235beb1d3cbb734e4542a78a77d1c6de 487 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 287 303 2.3E-69 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 VMUT_1677 235beb1d3cbb734e4542a78a77d1c6de 487 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 327 346 2.3E-69 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 VMUT_1677 235beb1d3cbb734e4542a78a77d1c6de 487 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 240 259 2.3E-69 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 VMUT_1677 235beb1d3cbb734e4542a78a77d1c6de 487 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 260 279 2.3E-69 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 VMUT_1677 235beb1d3cbb734e4542a78a77d1c6de 487 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 373 390 2.3E-69 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 VMUT_1677 235beb1d3cbb734e4542a78a77d1c6de 487 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 223 239 2.3E-69 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 VMUT_1677 235beb1d3cbb734e4542a78a77d1c6de 487 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 141 161 2.3E-69 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 VMUT_1677 235beb1d3cbb734e4542a78a77d1c6de 487 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 15 485 9.4E-95 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 VMUT_1677 235beb1d3cbb734e4542a78a77d1c6de 487 SUPERFAMILY SSF55486 5 486 1.16E-105 T 23-10-2018 VMUT_1677 235beb1d3cbb734e4542a78a77d1c6de 487 Gene3D G3DSA:1.10.1370.30 1 486 1.2E-179 T 23-10-2018 VMUT_1677 235beb1d3cbb734e4542a78a77d1c6de 487 PIRSF PIRSF006615 1 487 1.4E-187 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 VMUT_0367 e90eb33db19cf4b6bb1932c31637ffb1 214 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 23 200 5.0E-70 T 23-10-2018 IPR005273 Uracil-DNA glycosylase family 4 VMUT_0367 e90eb33db19cf4b6bb1932c31637ffb1 214 Pfam PF03167 Uracil DNA glycosylase superfamily 37 193 3.4E-46 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VMUT_0367 e90eb33db19cf4b6bb1932c31637ffb1 214 Gene3D G3DSA:3.40.470.10 11 203 1.3E-69 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VMUT_0367 e90eb33db19cf4b6bb1932c31637ffb1 214 SMART SM00987 37 194 1.2E-39 T 23-10-2018 VMUT_0367 e90eb33db19cf4b6bb1932c31637ffb1 214 SUPERFAMILY SSF52141 12 201 5.89E-61 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VMUT_0367 e90eb33db19cf4b6bb1932c31637ffb1 214 SMART SM00986 37 194 1.2E-39 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VMUT_1678 c27b5b029cdd00cc95b6976e598446ad 218 SUPERFAMILY SSF52980 4 110 4.18E-16 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 VMUT_1678 c27b5b029cdd00cc95b6976e598446ad 218 Gene3D G3DSA:3.40.1350.10 8 108 1.7E-7 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 VMUT_1678 c27b5b029cdd00cc95b6976e598446ad 218 Pfam PF04471 Restriction endonuclease 4 107 3.5E-8 T 23-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 VMUT_2099 6b5301debc10c6beda9cf2697908c8f2 91 Gene3D G3DSA:3.30.1360.10 1 89 3.1E-21 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_2099 6b5301debc10c6beda9cf2697908c8f2 91 Hamap MF_00261 DNA-directed RNA polymerase subunit L [rpoL]. 2 87 17.369 T 23-10-2018 IPR022905 DNA-directed RNA polymerase subunit L (Rpo11) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_2099 6b5301debc10c6beda9cf2697908c8f2 91 SUPERFAMILY SSF55257 3 89 5.89E-22 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VMUT_2099 6b5301debc10c6beda9cf2697908c8f2 91 Pfam PF13656 RNA polymerase Rpb3/Rpb11 dimerisation domain 15 85 1.1E-19 T 23-10-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 VMUT_0233 20888a968cfe7c2192b99134ef75982b 154 Pfam PF00293 NUDIX domain 13 135 3.1E-20 T 23-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 VMUT_0233 20888a968cfe7c2192b99134ef75982b 154 ProSitePatterns PS00893 Nudix box signature. 42 63 - T 23-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 VMUT_0233 20888a968cfe7c2192b99134ef75982b 154 Gene3D G3DSA:3.90.79.10 2 140 2.3E-34 T 23-10-2018 VMUT_0233 20888a968cfe7c2192b99134ef75982b 154 SUPERFAMILY SSF55811 5 141 1.21E-34 T 23-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 VMUT_0233 20888a968cfe7c2192b99134ef75982b 154 PRINTS PR00502 NUDIX hydrolase family signature 37 51 1.6E-7 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 VMUT_0233 20888a968cfe7c2192b99134ef75982b 154 PRINTS PR00502 NUDIX hydrolase family signature 51 66 1.6E-7 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 VMUT_1391 8e3ff84bbee93f0e4ad9ac62383d65b3 234 Pfam PF01966 HD domain 42 107 6.8E-6 T 23-10-2018 IPR006674 HD domain VMUT_1391 8e3ff84bbee93f0e4ad9ac62383d65b3 234 SUPERFAMILY SSF109604 37 119 1.05E-9 T 23-10-2018 VMUT_1391 8e3ff84bbee93f0e4ad9ac62383d65b3 234 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 21 127 4.4E-17 T 23-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain VMUT_1391 8e3ff84bbee93f0e4ad9ac62383d65b3 234 Gene3D G3DSA:1.10.3210.30 12 191 4.2E-20 T 23-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily VMUT_1225 9ced3b72aa1989168c475fd247c1222d 430 Gene3D G3DSA:3.30.930.10 3 328 7.2E-103 T 23-10-2018 VMUT_1225 9ced3b72aa1989168c475fd247c1222d 430 SUPERFAMILY SSF52954 343 423 6.87E-15 T 23-10-2018 VMUT_1225 9ced3b72aa1989168c475fd247c1222d 430 Pfam PF13393 Histidyl-tRNA synthetase 13 323 3.7E-65 T 23-10-2018 VMUT_1225 9ced3b72aa1989168c475fd247c1222d 430 Gene3D G3DSA:3.40.50.800 339 427 9.2E-17 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily VMUT_1225 9ced3b72aa1989168c475fd247c1222d 430 SUPERFAMILY SSF55681 9 328 3.58E-75 T 23-10-2018 VMUT_1225 9ced3b72aa1989168c475fd247c1222d 430 PIRSF PIRSF001549 5 428 3.0E-125 T 23-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 VMUT_1225 9ced3b72aa1989168c475fd247c1222d 430 Pfam PF03129 Anticodon binding domain 345 422 6.7E-9 T 23-10-2018 IPR004154 Anticodon-binding VMUT_1225 9ced3b72aa1989168c475fd247c1222d 430 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 20 385 24.788 T 23-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 VMUT_1225 9ced3b72aa1989168c475fd247c1222d 430 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 6 430 28.408 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 VMUT_1225 9ced3b72aa1989168c475fd247c1222d 430 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 10 421 5.2E-113 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 VMUT_1245 20222a17b9a00d4d984e5adc27421f51 471 Gene3D G3DSA:1.20.1250.20 28 453 6.0E-57 T 23-10-2018 VMUT_1245 20222a17b9a00d4d984e5adc27421f51 471 Pfam PF00083 Sugar (and other) transporter 56 450 1.2E-26 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VMUT_1245 20222a17b9a00d4d984e5adc27421f51 471 SUPERFAMILY SSF103473 26 461 9.16E-52 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_1245 20222a17b9a00d4d984e5adc27421f51 471 ProSitePatterns PS00217 Sugar transport proteins signature 2. 129 154 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VMUT_1676 94a01d1334a75b5706ed14b27a4bc656 366 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 15 363 35.983 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 VMUT_1676 94a01d1334a75b5706ed14b27a4bc656 366 Gene3D G3DSA:1.20.120.420 15 164 1.0E-37 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 VMUT_1676 94a01d1334a75b5706ed14b27a4bc656 366 Pfam PF01008 Initiation factor 2 subunit family 60 353 7.6E-76 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 VMUT_1676 94a01d1334a75b5706ed14b27a4bc656 366 SUPERFAMILY SSF100950 16 355 4.52E-107 T 23-10-2018 IPR037171 NagB/RpiA transferase-like VMUT_1676 94a01d1334a75b5706ed14b27a4bc656 366 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 19 352 3.3E-107 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 VMUT_1676 94a01d1334a75b5706ed14b27a4bc656 366 Gene3D G3DSA:3.40.50.10470 165 366 9.0E-61 T 23-10-2018 VMUT_1676 94a01d1334a75b5706ed14b27a4bc656 366 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 51 353 5.9E-103 T 23-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 VMUT_1412 a24e26b03ad538c1141407a052650761 473 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 25 461 8.6E-162 T 23-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 VMUT_1412 a24e26b03ad538c1141407a052650761 473 SUPERFAMILY SSF101960 39 466 1.1E-110 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily VMUT_1412 a24e26b03ad538c1141407a052650761 473 Pfam PF01458 Uncharacterized protein family (UPF0051) 217 442 1.1E-60 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 VMUT_1080 534f0bf31996bba1b000f37dd2c71e1f 335 Pfam PF00535 Glycosyl transferase family 2 5 139 7.1E-19 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VMUT_1080 534f0bf31996bba1b000f37dd2c71e1f 335 SUPERFAMILY SSF53448 4 323 6.47E-48 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1080 534f0bf31996bba1b000f37dd2c71e1f 335 Gene3D G3DSA:3.90.550.10 2 222 3.2E-41 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0834 f33581f23a22640ec012e9b9dba2a2db 176 Gene3D G3DSA:3.30.460.40 1 136 2.2E-7 T 23-10-2018 VMUT_0834 f33581f23a22640ec012e9b9dba2a2db 176 Pfam PF09970 Nucleotidyl transferase of unknown function (DUF2204) 6 137 1.6E-4 T 23-10-2018 IPR018700 Protein of unknown function DUF2204 VMUT_0834 f33581f23a22640ec012e9b9dba2a2db 176 SUPERFAMILY SSF81301 3 136 3.6E-12 T 23-10-2018 VMUT_2229 0b4de282686a3311aa774dcfc920e33f 190 Gene3D G3DSA:1.20.1540.10 3 189 4.3E-23 T 23-10-2018 IPR035952 Rhomboid-like superfamily VMUT_2229 0b4de282686a3311aa774dcfc920e33f 190 Pfam PF01694 Rhomboid family 48 183 1.4E-19 T 23-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 VMUT_2229 0b4de282686a3311aa774dcfc920e33f 190 SUPERFAMILY SSF144091 5 185 1.24E-25 T 23-10-2018 VMUT_1252 b8e554d47cd54b3f289f9a235750ddaa 325 SUPERFAMILY SSF51735 4 155 2.23E-42 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1252 b8e554d47cd54b3f289f9a235750ddaa 325 Gene3D G3DSA:3.30.360.10 133 315 6.1E-62 T 23-10-2018 VMUT_1252 b8e554d47cd54b3f289f9a235750ddaa 325 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 122 1.2E-23 T 23-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 VMUT_1252 b8e554d47cd54b3f289f9a235750ddaa 325 SUPERFAMILY SSF55347 131 281 7.85E-18 T 23-10-2018 VMUT_1252 b8e554d47cd54b3f289f9a235750ddaa 325 Gene3D G3DSA:3.40.50.720 7 301 6.1E-62 T 23-10-2018 VMUT_1457 b38da0826ce3297109c1b112fad8587b 399 Pfam PF00999 Sodium/hydrogen exchanger family 16 382 8.1E-48 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 VMUT_1457 b38da0826ce3297109c1b112fad8587b 399 Gene3D G3DSA:1.20.1530.20 8 392 1.2E-69 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily VMUT_0755 914001a3c2cb2b67103cd25a186ea866 130 SUPERFAMILY SSF56047 2 130 1.11E-35 T 23-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0755 914001a3c2cb2b67103cd25a186ea866 130 Pfam PF00410 Ribosomal protein S8 5 130 1.2E-24 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0755 914001a3c2cb2b67103cd25a186ea866 130 Gene3D G3DSA:3.30.1490.10 70 128 7.2E-24 T 23-10-2018 VMUT_0755 914001a3c2cb2b67103cd25a186ea866 130 Hamap MF_01302_A 30S ribosomal protein S8 [rpsH]. 2 130 35.853 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0755 914001a3c2cb2b67103cd25a186ea866 130 ProSitePatterns PS00053 Ribosomal protein S8 signature. 100 117 - T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0755 914001a3c2cb2b67103cd25a186ea866 130 Gene3D G3DSA:3.30.1370.30 1 69 2.2E-30 T 23-10-2018 VMUT_1342 f51f2320f85ec2ef8ba44d98fd1ff40d 325 Gene3D G3DSA:1.10.8.60 178 253 1.9E-20 T 23-10-2018 VMUT_1342 f51f2320f85ec2ef8ba44d98fd1ff40d 325 Gene3D G3DSA:3.40.50.300 1 175 4.6E-28 T 23-10-2018 VMUT_1342 f51f2320f85ec2ef8ba44d98fd1ff40d 325 SUPERFAMILY SSF46785 253 321 3.36E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_1342 f51f2320f85ec2ef8ba44d98fd1ff40d 325 SUPERFAMILY SSF52540 2 234 6.61E-32 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1342 f51f2320f85ec2ef8ba44d98fd1ff40d 325 Gene3D G3DSA:1.10.10.10 254 323 2.6E-16 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_2263 2e1535eb34bf57790c4b9f2d63cccd05 161 Pfam PF00293 NUDIX domain 16 125 4.2E-18 T 23-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 VMUT_2263 2e1535eb34bf57790c4b9f2d63cccd05 161 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 87 106 7.0E-20 T 23-10-2018 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502|Reactome: R-HSA-2393930 VMUT_2263 2e1535eb34bf57790c4b9f2d63cccd05 161 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 107 125 7.0E-20 T 23-10-2018 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502|Reactome: R-HSA-2393930 VMUT_2263 2e1535eb34bf57790c4b9f2d63cccd05 161 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 126 144 7.0E-20 T 23-10-2018 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502|Reactome: R-HSA-2393930 VMUT_2263 2e1535eb34bf57790c4b9f2d63cccd05 161 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 6 23 7.0E-20 T 23-10-2018 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502|Reactome: R-HSA-2393930 VMUT_2263 2e1535eb34bf57790c4b9f2d63cccd05 161 PRINTS PR01403 7,8-dihydro-8-oxoguanine triphosphatase signature 23 39 7.0E-20 T 23-10-2018 IPR003563 7,8-dihydro-8-oxoguanine triphosphatase GO:0006281|GO:0008413 MetaCyc: PWY-6502|Reactome: R-HSA-2393930 VMUT_2263 2e1535eb34bf57790c4b9f2d63cccd05 161 SUPERFAMILY SSF55811 10 137 6.5E-29 T 23-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 VMUT_2263 2e1535eb34bf57790c4b9f2d63cccd05 161 Gene3D G3DSA:3.90.79.10 8 158 4.0E-45 T 23-10-2018 VMUT_0634 75709935c78ba65c9b751838afa5dbcd 377 Pfam PF13183 4Fe-4S dicluster domain 24 82 1.2E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_0634 75709935c78ba65c9b751838afa5dbcd 377 Pfam PF02754 Cysteine-rich domain 144 230 1.0E-7 T 23-10-2018 IPR004017 Cysteine-rich domain VMUT_0634 75709935c78ba65c9b751838afa5dbcd 377 Pfam PF02754 Cysteine-rich domain 264 351 5.8E-17 T 23-10-2018 IPR004017 Cysteine-rich domain VMUT_0634 75709935c78ba65c9b751838afa5dbcd 377 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 68 79 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_0634 75709935c78ba65c9b751838afa5dbcd 377 SUPERFAMILY SSF46548 18 102 1.74E-14 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VMUT_0634 75709935c78ba65c9b751838afa5dbcd 377 Gene3D G3DSA:1.10.1060.10 14 97 7.4E-10 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VMUT_1716 3a1deaccbc646769d95299d4764fb6c4 143 SUPERFAMILY SSF52540 10 141 2.2E-8 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1716 3a1deaccbc646769d95299d4764fb6c4 143 Gene3D G3DSA:3.40.50.300 2 143 3.6E-10 T 23-10-2018 VMUT_0657 8a3b312c8861c3311f920a9244590fcc 228 Pfam PF03458 UPF0126 domain 10 84 6.5E-17 T 23-10-2018 IPR005115 Uncharacterised domain UPF0126 VMUT_0657 8a3b312c8861c3311f920a9244590fcc 228 Pfam PF03458 UPF0126 domain 96 169 1.4E-22 T 23-10-2018 IPR005115 Uncharacterised domain UPF0126 VMUT_0904 f6840ba272281bb281166ac1fd84a69e 303 SUPERFAMILY SSF56281 3 283 1.05E-44 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_0904 f6840ba272281bb281166ac1fd84a69e 303 SMART SM00849 24 218 7.1E-29 T 23-10-2018 IPR001279 Metallo-beta-lactamase VMUT_0904 f6840ba272281bb281166ac1fd84a69e 303 Gene3D G3DSA:3.60.15.10 7 268 6.5E-50 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_0904 f6840ba272281bb281166ac1fd84a69e 303 Pfam PF00753 Metallo-beta-lactamase superfamily 25 218 1.2E-16 T 23-10-2018 IPR001279 Metallo-beta-lactamase VMUT_1387 4dae764f93de4241bdcbe62b1197bf2e 275 Gene3D G3DSA:3.40.190.80 151 272 5.4E-11 T 23-10-2018 VMUT_1387 4dae764f93de4241bdcbe62b1197bf2e 275 Gene3D G3DSA:3.30.540.10 2 145 7.4E-21 T 23-10-2018 VMUT_1387 4dae764f93de4241bdcbe62b1197bf2e 275 SUPERFAMILY SSF56655 7 265 8.51E-31 T 23-10-2018 VMUT_1387 4dae764f93de4241bdcbe62b1197bf2e 275 Pfam PF00459 Inositol monophosphatase family 11 231 5.1E-16 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 VMUT_0077 ef11774df08ad0a5ac96445f40a9c08d 326 SUPERFAMILY SSF51735 1 315 1.77E-90 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0077 ef11774df08ad0a5ac96445f40a9c08d 326 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 5 314 1.7E-122 T 23-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 VMUT_0077 ef11774df08ad0a5ac96445f40a9c08d 326 Gene3D G3DSA:3.90.25.10 187 308 8.6E-108 T 23-10-2018 VMUT_0077 ef11774df08ad0a5ac96445f40a9c08d 326 Gene3D G3DSA:3.40.50.720 5 299 8.6E-108 T 23-10-2018 VMUT_0077 ef11774df08ad0a5ac96445f40a9c08d 326 Pfam PF16363 GDP-mannose 4,6 dehydratase 7 300 6.3E-71 T 23-10-2018 IPR016040 NAD(P)-binding domain VMUT_0928 fdeb176a746330bbb33da2832bf64a14 155 Pfam PF09921 Uncharacterized protein conserved in archaea (DUF2153) 21 142 1.2E-44 T 23-10-2018 IPR014450 Uncharacterised conserved protein UCP008210 VMUT_1829 81a53b73c8bdc2e665a089c48d91055a 193 Pfam PF01914 MarC family integral membrane protein 4 186 3.1E-33 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 VMUT_1829 81a53b73c8bdc2e665a089c48d91055a 193 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 5 183 1.2E-32 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 VMUT_0276 05a025a67bc74d43da7558f37e23982b 146 Pfam PF10051 Uncharacterized protein conserved in archaea (DUF2286) 8 142 2.5E-43 T 23-10-2018 IPR017006 Uncharacterised conserved protein UCP032756 VMUT_0366 16515c4e48ca712f4c7abf8f098922da 67 Hamap MF_01387 Chromatin protein Cren7 [creN7]. 4 61 20.144 T 23-10-2018 IPR020906 Double-stranded DNA-binding Cren7 GO:0003690|GO:0005737 VMUT_0366 16515c4e48ca712f4c7abf8f098922da 67 Pfam PF11520 Chromatin protein Cren7 8 57 1.7E-17 T 23-10-2018 IPR020906 Double-stranded DNA-binding Cren7 GO:0003690|GO:0005737 VMUT_0366 16515c4e48ca712f4c7abf8f098922da 67 Gene3D G3DSA:2.30.30.610 9 59 2.2E-9 T 23-10-2018 IPR038647 Cren7 superfamily VMUT_2053 05879494e8c224173f178134fe3c8ffd 205 Pfam PF02581 Thiamine monophosphate synthase 7 185 1.7E-54 T 23-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 VMUT_2053 05879494e8c224173f178134fe3c8ffd 205 Gene3D G3DSA:3.20.20.70 3 205 2.0E-62 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_2053 05879494e8c224173f178134fe3c8ffd 205 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 5 203 25.883 T 23-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 VMUT_2053 05879494e8c224173f178134fe3c8ffd 205 SUPERFAMILY SSF51391 5 203 2.49E-61 T 23-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 VMUT_2053 05879494e8c224173f178134fe3c8ffd 205 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 7 197 5.4E-52 T 23-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 VMUT_1768 4c9ec56cdf711bac4b3906afa1edb81e 81 Gene3D G3DSA:3.30.70.330 1 81 3.0E-26 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily VMUT_1768 4c9ec56cdf711bac4b3906afa1edb81e 81 TIGRFAM TIGR03636 uL23_arch: ribosomal protein uL23 6 80 1.7E-31 T 23-10-2018 IPR019985 Ribosomal protein L23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1768 4c9ec56cdf711bac4b3906afa1edb81e 81 Pfam PF00276 Ribosomal protein L23 2 65 5.7E-15 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 VMUT_1768 4c9ec56cdf711bac4b3906afa1edb81e 81 ProSitePatterns PS00050 Ribosomal protein L23 signature. 59 74 - T 23-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1768 4c9ec56cdf711bac4b3906afa1edb81e 81 SUPERFAMILY SSF54189 2 72 2.59E-21 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_1768 4c9ec56cdf711bac4b3906afa1edb81e 81 Hamap MF_01369_A 50S ribosomal protein L23 [rplW]. 1 81 22.586 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 VMUT_0131 eb6eeda2728b74ca8a936c80b3c1f81c 516 SUPERFAMILY SSF53756 8 512 2.97E-87 T 23-10-2018 VMUT_0131 eb6eeda2728b74ca8a936c80b3c1f81c 516 Pfam PF00343 Carbohydrate phosphorylase 280 480 5.6E-15 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 VMUT_0131 eb6eeda2728b74ca8a936c80b3c1f81c 516 Gene3D G3DSA:3.40.50.2000 242 509 1.2E-29 T 23-10-2018 VMUT_0925 98d8e476505c2029c532a8680d4e07e3 130 Gene3D G3DSA:3.40.50.280 2 130 9.0E-54 T 23-10-2018 VMUT_0925 98d8e476505c2029c532a8680d4e07e3 130 Pfam PF02310 B12 binding domain 5 115 7.6E-25 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 VMUT_0925 98d8e476505c2029c532a8680d4e07e3 130 SUPERFAMILY SSF52242 3 125 1.24E-45 T 23-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 VMUT_0925 98d8e476505c2029c532a8680d4e07e3 130 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 3 127 2.1E-48 T 23-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 VMUT_2294 9f50e6f612f53b6a9444cd3c05fb2a51 385 PIRSF PIRSF000429 2 371 4.1E-33 T 23-10-2018 IPR002155 Thiolase GO:0016747 VMUT_2294 9f50e6f612f53b6a9444cd3c05fb2a51 385 Pfam PF00108 Thiolase, N-terminal domain 25 223 4.6E-10 T 23-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 VMUT_2294 9f50e6f612f53b6a9444cd3c05fb2a51 385 Pfam PF02803 Thiolase, C-terminal domain 260 350 1.3E-4 T 23-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 VMUT_2294 9f50e6f612f53b6a9444cd3c05fb2a51 385 Gene3D G3DSA:3.40.47.10 6 383 1.8E-80 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_2294 9f50e6f612f53b6a9444cd3c05fb2a51 385 SUPERFAMILY SSF53901 26 350 1.73E-25 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_2135 6433e81322c60e1add7081376d01af5e 220 Gene3D G3DSA:3.20.20.70 2 218 1.7E-44 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_2135 6433e81322c60e1add7081376d01af5e 220 SUPERFAMILY SSF51366 5 216 8.87E-39 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 VMUT_2135 6433e81322c60e1add7081376d01af5e 220 SMART SM00934 7 211 3.6E-18 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VMUT_2135 6433e81322c60e1add7081376d01af5e 220 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 8 207 2.3E-16 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VMUT_0234 9b01e2f7a268763e243fd1a8d4a070bd 91 SUPERFAMILY SSF54975 1 91 5.67E-29 T 23-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 VMUT_0234 9b01e2f7a268763e243fd1a8d4a070bd 91 Pfam PF00708 Acylphosphatase 5 89 9.9E-30 T 23-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 VMUT_0234 9b01e2f7a268763e243fd1a8d4a070bd 91 ProSitePatterns PS00150 Acylphosphatase signature 1. 8 18 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 VMUT_0234 9b01e2f7a268763e243fd1a8d4a070bd 91 Gene3D G3DSA:3.30.70.100 1 90 3.0E-33 T 23-10-2018 VMUT_0537 fc114bc05639f0e167c09b5b42e725cc 307 SMART SM01329 2 300 1.2E-89 T 23-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 VMUT_0537 fc114bc05639f0e167c09b5b42e725cc 307 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 3 292 1.6E-70 T 23-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 VMUT_0537 fc114bc05639f0e167c09b5b42e725cc 307 Gene3D G3DSA:3.40.718.10 1 294 4.7E-95 T 23-10-2018 VMUT_0537 fc114bc05639f0e167c09b5b42e725cc 307 SUPERFAMILY SSF53659 2 303 2.34E-85 T 23-10-2018 VMUT_0290 545b9c7348171980096213c8db0063ab 59 SUPERFAMILY SSF57783 3 43 5.95E-8 T 23-10-2018 VMUT_0290 545b9c7348171980096213c8db0063ab 59 Pfam PF01096 Transcription factor S-II (TFIIS) 3 40 1.3E-5 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 VMUT_2255 e0555c50eda988516a843a4a3907dbfc 315 ProSitePatterns PS01322 Phosphotriesterase family signature 1. 18 26 - T 23-10-2018 IPR017947 Aryldialkylphosphatase, zinc-binding site GO:0008270|GO:0009056|GO:0016788 VMUT_2255 e0555c50eda988516a843a4a3907dbfc 315 SUPERFAMILY SSF51556 11 313 9.24E-71 T 23-10-2018 IPR032466 Metal-dependent hydrolase VMUT_2255 e0555c50eda988516a843a4a3907dbfc 315 Pfam PF02126 Phosphotriesterase family 12 313 1.0E-77 T 23-10-2018 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 VMUT_2255 e0555c50eda988516a843a4a3907dbfc 315 Gene3D G3DSA:3.20.20.140 1 315 9.0E-106 T 23-10-2018 VMUT_1743 4e635ff3aaf54f10c16211907287fde9 123 SUPERFAMILY SSF54197 3 117 2.04E-23 T 23-10-2018 IPR036265 HIT-like superfamily VMUT_1743 4e635ff3aaf54f10c16211907287fde9 123 Gene3D G3DSA:3.30.428.10 2 121 1.5E-27 T 23-10-2018 IPR036265 HIT-like superfamily VMUT_1970 5f50ca1d2b4fc8e612f28ad7d112c21a 159 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 8 98 2.7E-33 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal VMUT_1970 5f50ca1d2b4fc8e612f28ad7d112c21a 159 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 4 154 33.657 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 VMUT_1970 5f50ca1d2b4fc8e612f28ad7d112c21a 159 SUPERFAMILY SSF57825 102 154 4.19E-15 T 23-10-2018 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily VMUT_1970 5f50ca1d2b4fc8e612f28ad7d112c21a 159 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 5 150 7.0E-54 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 VMUT_1970 5f50ca1d2b4fc8e612f28ad7d112c21a 159 SUPERFAMILY SSF54893 3 101 8.89E-34 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily VMUT_1970 5f50ca1d2b4fc8e612f28ad7d112c21a 159 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 9 97 3.0E-25 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal VMUT_1970 5f50ca1d2b4fc8e612f28ad7d112c21a 159 Gene3D G3DSA:2.30.30.20 101 158 1.1E-17 T 23-10-2018 VMUT_1970 5f50ca1d2b4fc8e612f28ad7d112c21a 159 Gene3D G3DSA:3.30.70.140 1 100 2.4E-38 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily VMUT_1970 5f50ca1d2b4fc8e612f28ad7d112c21a 159 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 104 152 2.5E-18 T 23-10-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal VMUT_0267 75004cddb0b7565fb469082c7d320b3e 397 SUPERFAMILY SSF53448 9 288 5.18E-35 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0267 75004cddb0b7565fb469082c7d320b3e 397 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 270 303 5.5E-6 T 23-10-2018 IPR001451 Hexapeptide repeat VMUT_0267 75004cddb0b7565fb469082c7d320b3e 397 Gene3D G3DSA:3.90.550.10 2 220 4.4E-22 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0267 75004cddb0b7565fb469082c7d320b3e 397 Gene3D G3DSA:2.160.10.10 221 397 3.8E-37 T 23-10-2018 VMUT_0267 75004cddb0b7565fb469082c7d320b3e 397 Pfam PF00483 Nucleotidyl transferase 11 163 2.0E-14 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 VMUT_0267 75004cddb0b7565fb469082c7d320b3e 397 SUPERFAMILY SSF51161 234 395 1.67E-26 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily VMUT_2071 e3b9dd1c2d83d7f4ab9eb5733d864fcc 392 Gene3D G3DSA:1.20.1250.20 4 181 7.1E-18 T 23-10-2018 VMUT_2071 e3b9dd1c2d83d7f4ab9eb5733d864fcc 392 Pfam PF00083 Sugar (and other) transporter 37 173 9.6E-16 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VMUT_2071 e3b9dd1c2d83d7f4ab9eb5733d864fcc 392 SUPERFAMILY SSF103473 7 374 1.28E-29 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_2071 e3b9dd1c2d83d7f4ab9eb5733d864fcc 392 Gene3D G3DSA:1.20.1250.20 189 380 1.7E-6 T 23-10-2018 VMUT_1947 7fc56bae1d374e5c3cb8d267b298349b 542 Gene3D G3DSA:2.130.10.10 155 245 1.7E-6 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 VMUT_1947 7fc56bae1d374e5c3cb8d267b298349b 542 SUPERFAMILY SSF51004 23 144 1.94E-7 T 23-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily VMUT_1947 7fc56bae1d374e5c3cb8d267b298349b 542 SUPERFAMILY SSF51004 163 421 5.49E-24 T 23-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily VMUT_1947 7fc56bae1d374e5c3cb8d267b298349b 542 Gene3D G3DSA:2.130.10.10 18 147 1.6E-8 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 VMUT_1947 7fc56bae1d374e5c3cb8d267b298349b 542 Gene3D G3DSA:2.130.10.10 252 420 1.5E-17 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 VMUT_1051 f7ab2a7a2cd28687ed6dd4a7bfe486bb 305 SUPERFAMILY SSF53448 6 227 1.74E-40 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1051 f7ab2a7a2cd28687ed6dd4a7bfe486bb 305 Pfam PF00535 Glycosyl transferase family 2 8 166 4.3E-22 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VMUT_1051 f7ab2a7a2cd28687ed6dd4a7bfe486bb 305 Gene3D G3DSA:3.90.550.10 3 211 1.5E-36 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1426 9492a0a23f247ca903d4ab92578100cf 569 SUPERFAMILY SSF52922 435 568 1.15E-26 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VMUT_1426 9492a0a23f247ca903d4ab92578100cf 569 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 37 254 1.8E-36 T 23-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 VMUT_1426 9492a0a23f247ca903d4ab92578100cf 569 Pfam PF02780 Transketolase, C-terminal domain 444 559 1.7E-21 T 23-10-2018 IPR033248 Transketolase, C-terminal domain VMUT_1426 9492a0a23f247ca903d4ab92578100cf 569 SUPERFAMILY SSF52518 259 429 1.34E-48 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold VMUT_1426 9492a0a23f247ca903d4ab92578100cf 569 Gene3D G3DSA:3.40.50.920 441 569 2.8E-31 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VMUT_1426 9492a0a23f247ca903d4ab92578100cf 569 SUPERFAMILY SSF52518 32 264 8.84E-65 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold VMUT_1426 9492a0a23f247ca903d4ab92578100cf 569 Gene3D G3DSA:3.40.50.970 248 440 3.5E-54 T 23-10-2018 VMUT_1426 9492a0a23f247ca903d4ab92578100cf 569 Pfam PF02779 Transketolase, pyrimidine binding domain 265 424 8.6E-34 T 23-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain VMUT_1426 9492a0a23f247ca903d4ab92578100cf 569 SMART SM00861 265 430 3.4E-42 T 23-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain VMUT_1426 9492a0a23f247ca903d4ab92578100cf 569 Gene3D G3DSA:3.40.50.970 8 247 1.5E-48 T 23-10-2018 VMUT_1260 6afd50d384430d3ee84b2f5edacfd051 368 SUPERFAMILY SSF50331 240 353 8.99E-14 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal VMUT_1260 6afd50d384430d3ee84b2f5edacfd051 368 SMART SM00382 27 217 1.6E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_1260 6afd50d384430d3ee84b2f5edacfd051 368 Pfam PF00005 ABC transporter 19 165 2.3E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_1260 6afd50d384430d3ee84b2f5edacfd051 368 SUPERFAMILY SSF52540 2 248 4.6E-71 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1260 6afd50d384430d3ee84b2f5edacfd051 368 Gene3D G3DSA:3.40.50.300 1 241 6.1E-66 T 23-10-2018 VMUT_1260 6afd50d384430d3ee84b2f5edacfd051 368 Gene3D G3DSA:2.40.50.100 242 355 9.4E-7 T 23-10-2018 VMUT_1260 6afd50d384430d3ee84b2f5edacfd051 368 Gene3D G3DSA:2.40.50.140 277 344 9.4E-7 T 23-10-2018 VMUT_0187 ce918b081597673da3e6d4adbe06a6d5 290 SUPERFAMILY SSF53613 4 273 3.59E-37 T 23-10-2018 IPR029056 Ribokinase-like VMUT_0187 ce918b081597673da3e6d4adbe06a6d5 290 Pfam PF00294 pfkB family carbohydrate kinase 19 262 2.0E-13 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB VMUT_0187 ce918b081597673da3e6d4adbe06a6d5 290 Gene3D G3DSA:3.40.1190.20 2 278 4.9E-51 T 23-10-2018 IPR029056 Ribokinase-like VMUT_1870 f68f13e453cbf8d4156437d4442cb542 177 SUPERFAMILY SSF102405 3 165 4.27E-24 T 23-10-2018 VMUT_1870 f68f13e453cbf8d4156437d4442cb542 177 Gene3D G3DSA:3.40.50.450 3 167 1.9E-19 T 23-10-2018 VMUT_1448 668f899388ca3b16e9080bae23552aa6 122 Gene3D G3DSA:2.40.40.20 27 119 8.4E-6 T 23-10-2018 VMUT_0804 847f596ee92bd41e24c6aaae6fb7179c 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VMUT_0804 847f596ee92bd41e24c6aaae6fb7179c 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 248 1.3E-61 T 23-10-2018 VMUT_0804 847f596ee92bd41e24c6aaae6fb7179c 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 4.5E-43 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0804 847f596ee92bd41e24c6aaae6fb7179c 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 4.5E-43 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0804 847f596ee92bd41e24c6aaae6fb7179c 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 4.5E-43 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0804 847f596ee92bd41e24c6aaae6fb7179c 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 4.5E-43 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0804 847f596ee92bd41e24c6aaae6fb7179c 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 4.5E-43 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0804 847f596ee92bd41e24c6aaae6fb7179c 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 4.5E-43 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0804 847f596ee92bd41e24c6aaae6fb7179c 261 SUPERFAMILY SSF51735 4 249 1.59E-79 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0804 847f596ee92bd41e24c6aaae6fb7179c 261 Gene3D G3DSA:3.40.50.720 2 249 1.9E-78 T 23-10-2018 VMUT_0804 847f596ee92bd41e24c6aaae6fb7179c 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.1E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0804 847f596ee92bd41e24c6aaae6fb7179c 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.1E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0804 847f596ee92bd41e24c6aaae6fb7179c 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.1E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_1700 56f73b9ccb06d24c0ed1e2d660284f26 120 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 21 32 - T 23-10-2018 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 VMUT_1700 56f73b9ccb06d24c0ed1e2d660284f26 120 SUPERFAMILY SSF50630 18 102 2.25E-11 T 23-10-2018 IPR021109 Aspartic peptidase domain superfamily VMUT_1700 56f73b9ccb06d24c0ed1e2d660284f26 120 Gene3D G3DSA:2.40.70.10 1 111 2.0E-13 T 23-10-2018 IPR021109 Aspartic peptidase domain superfamily VMUT_1700 56f73b9ccb06d24c0ed1e2d660284f26 120 Pfam PF13975 gag-polyprotein putative aspartyl protease 18 95 7.6E-10 T 23-10-2018 VMUT_0362 66cf226c29a759b24b4e19c7bbf743df 561 ProSitePatterns PS00455 Putative AMP-binding domain signature. 194 205 - T 23-10-2018 IPR020845 AMP-binding, conserved site VMUT_0362 66cf226c29a759b24b4e19c7bbf743df 561 Pfam PF13193 AMP-binding enzyme C-terminal domain 464 545 2.7E-20 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VMUT_0362 66cf226c29a759b24b4e19c7bbf743df 561 Gene3D G3DSA:3.40.50.12780 2 449 2.2E-108 T 23-10-2018 VMUT_0362 66cf226c29a759b24b4e19c7bbf743df 561 SUPERFAMILY SSF56801 9 558 3.14E-132 T 23-10-2018 VMUT_0362 66cf226c29a759b24b4e19c7bbf743df 561 Gene3D G3DSA:3.30.300.310 450 560 1.5E-32 T 23-10-2018 VMUT_0362 66cf226c29a759b24b4e19c7bbf743df 561 Pfam PF00501 AMP-binding enzyme 25 454 5.4E-83 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VMUT_0792 ecc3612cbca7068369ed98aeb44c3f6d 173 Gene3D G3DSA:3.40.50.300 2 127 2.5E-20 T 23-10-2018 VMUT_0792 ecc3612cbca7068369ed98aeb44c3f6d 173 Gene3D G3DSA:1.10.8.60 128 173 1.1E-17 T 23-10-2018 VMUT_0792 ecc3612cbca7068369ed98aeb44c3f6d 173 Pfam PF01637 ATPase domain predominantly from Archaea 39 167 3.9E-9 T 23-10-2018 IPR011579 ATPase domain GO:0005524 VMUT_0792 ecc3612cbca7068369ed98aeb44c3f6d 173 SUPERFAMILY SSF52540 10 171 1.79E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0356 15845c7da55e8f2ccc6228ff76de0c64 430 Pfam PF01882 Protein of unknown function DUF58 199 285 5.9E-23 T 23-10-2018 IPR002881 Domain of unknown function DUF58 VMUT_1152 3e6c52c964bb76a9ae98449617dc1cbb 98 SMART SM00858 10 88 3.0E-17 T 23-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 VMUT_1152 3e6c52c964bb76a9ae98449617dc1cbb 98 Pfam PF08666 SAF domain 10 88 3.3E-16 T 23-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 VMUT_1152 3e6c52c964bb76a9ae98449617dc1cbb 98 Gene3D G3DSA:3.90.1210.30 2 90 8.2E-29 T 23-10-2018 VMUT_1722 44ac8a7f3ed2cc9963bad2e623b40f02 260 SUPERFAMILY SSF52980 61 259 3.49E-7 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 VMUT_1111 4be8d751d252d5fa37fee7a01a200e2d 429 Pfam PF01882 Protein of unknown function DUF58 262 327 3.3E-11 T 23-10-2018 IPR002881 Domain of unknown function DUF58 VMUT_0844 e1bdb2fa40b79a5c0ca579b0e8fe3a99 149 Pfam PF07849 Protein of unknown function (DUF1641) 105 137 7.8E-9 T 23-10-2018 IPR012440 Protein of unknown function DUF1641 VMUT_1592 03c057fafe116abf4f438c472c6c46fc 117 SUPERFAMILY SSF81301 3 97 1.16E-13 T 23-10-2018 VMUT_1592 03c057fafe116abf4f438c472c6c46fc 117 Pfam PF01909 Nucleotidyltransferase domain 5 72 3.4E-10 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 VMUT_1592 03c057fafe116abf4f438c472c6c46fc 117 Gene3D G3DSA:3.30.460.10 1 84 7.1E-12 T 23-10-2018 VMUT_0900 b33619700f2855da8f1a507580e4a525 149 Hamap MF_00814 Nascent polypeptide-associated complex protein [nac]. 6 141 17.797 T 23-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 VMUT_0900 b33619700f2855da8f1a507580e4a525 149 Gene3D G3DSA:1.10.8.10 102 140 3.0E-17 T 23-10-2018 VMUT_0900 b33619700f2855da8f1a507580e4a525 149 Gene3D G3DSA:2.20.70.30 11 71 3.2E-6 T 23-10-2018 IPR038187 NAC A/B domain superfamily VMUT_0900 b33619700f2855da8f1a507580e4a525 149 Pfam PF01849 NAC domain 5 61 1.2E-8 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain VMUT_0900 b33619700f2855da8f1a507580e4a525 149 SMART SM01407 5 69 2.0E-14 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain VMUT_0900 b33619700f2855da8f1a507580e4a525 149 SUPERFAMILY SSF46934 88 143 1.19E-9 T 23-10-2018 IPR009060 UBA-like superfamily GO:0005515 VMUT_1698 238b54b31f5fa570fab0af7bae78dc6e 107 SUPERFAMILY SSF81301 16 89 1.24E-12 T 23-10-2018 VMUT_1698 238b54b31f5fa570fab0af7bae78dc6e 107 Gene3D G3DSA:3.30.460.10 9 96 2.0E-10 T 23-10-2018 VMUT_1698 238b54b31f5fa570fab0af7bae78dc6e 107 Pfam PF01909 Nucleotidyltransferase domain 28 71 2.5E-7 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 VMUT_1256 943c433e1f5652369b41f72fe1a5c3d9 119 Gene3D G3DSA:3.90.1210.30 25 110 5.5E-31 T 23-10-2018 VMUT_1256 943c433e1f5652369b41f72fe1a5c3d9 119 Pfam PF08666 SAF domain 33 108 5.4E-20 T 23-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 VMUT_1256 943c433e1f5652369b41f72fe1a5c3d9 119 SMART SM00858 33 108 2.3E-15 T 23-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 VMUT_1295 4f8aeb4c8c09f37b2f727c41c9735c64 146 Gene3D G3DSA:3.30.1440.10 3 146 6.5E-39 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1295 4f8aeb4c8c09f37b2f727c41c9735c64 146 SUPERFAMILY SSF55282 6 141 6.77E-33 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1295 4f8aeb4c8c09f37b2f727c41c9735c64 146 Pfam PF01877 RNA binding 6 126 1.1E-30 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 VMUT_0335 4ad178c50eee2410b0e45d61c3fe3abd 314 ProSitePatterns PS00161 Isocitrate lyase signature. 130 135 - T 23-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 VMUT_0335 4ad178c50eee2410b0e45d61c3fe3abd 314 Pfam PF13714 Phosphoenolpyruvate phosphomutase 22 261 1.2E-58 T 23-10-2018 VMUT_0335 4ad178c50eee2410b0e45d61c3fe3abd 314 Gene3D G3DSA:3.20.20.60 4 306 9.1E-110 T 23-10-2018 VMUT_0335 4ad178c50eee2410b0e45d61c3fe3abd 314 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 20 299 5.5E-125 T 23-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 VMUT_0335 4ad178c50eee2410b0e45d61c3fe3abd 314 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 15 301 47.743 T 23-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 VMUT_0335 4ad178c50eee2410b0e45d61c3fe3abd 314 SUPERFAMILY SSF51621 15 309 2.87E-101 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 VMUT_2008 8f73493a47834333bb42814201a81d5c 245 Gene3D G3DSA:3.40.50.10310 1 236 3.4E-65 T 23-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 VMUT_2008 8f73493a47834333bb42814201a81d5c 245 SUPERFAMILY SSF102215 1 235 1.96E-57 T 23-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 VMUT_2008 8f73493a47834333bb42814201a81d5c 245 Pfam PF02633 Creatinine amidohydrolase 5 231 4.9E-59 T 23-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 VMUT_0281 3d8a9100215093292baaec811cb4e055 181 Pfam PF01467 Cytidylyltransferase-like 8 138 1.8E-10 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 VMUT_0281 3d8a9100215093292baaec811cb4e055 181 Gene3D G3DSA:3.40.50.620 4 177 1.2E-44 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_0281 3d8a9100215093292baaec811cb4e055 181 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 6 67 1.6E-13 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 VMUT_0281 3d8a9100215093292baaec811cb4e055 181 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 181 86.412 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 VMUT_0281 3d8a9100215093292baaec811cb4e055 181 TIGRFAM TIGR01527 arch_NMN_Atrans: nicotinamide-nucleotide adenylyltransferase 6 172 5.5E-60 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 VMUT_0281 3d8a9100215093292baaec811cb4e055 181 SUPERFAMILY SSF52374 6 169 6.57E-28 T 23-10-2018 VMUT_0819 e133b664c5b19239fadad36ec5a085ad 89 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 11 50 9.4E-11 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VMUT_0819 e133b664c5b19239fadad36ec5a085ad 89 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 10 45 1.5E-11 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VMUT_0819 e133b664c5b19239fadad36ec5a085ad 89 Gene3D G3DSA:2.10.260.10 5 45 6.9E-11 T 23-10-2018 VMUT_0819 e133b664c5b19239fadad36ec5a085ad 89 SUPERFAMILY SSF89447 11 49 2.79E-10 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily VMUT_0819 e133b664c5b19239fadad36ec5a085ad 89 SMART SM00966 7 52 2.4E-6 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VMUT_0781 835d082b9f701f632af0a46dde49917c 329 Gene3D G3DSA:3.20.20.20 11 311 1.3E-79 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 VMUT_0781 835d082b9f701f632af0a46dde49917c 329 SUPERFAMILY SSF51717 13 309 1.96E-68 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 VMUT_0781 835d082b9f701f632af0a46dde49917c 329 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 59 72 - T 23-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 VMUT_0781 835d082b9f701f632af0a46dde49917c 329 Pfam PF00809 Pterin binding enzyme 232 292 4.2E-9 T 23-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 VMUT_0781 835d082b9f701f632af0a46dde49917c 329 Pfam PF00809 Pterin binding enzyme 27 195 6.4E-47 T 23-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 VMUT_2036 a13fd6f13de75b24292d2a7d8c2c921f 827 SUPERFAMILY SSF75712 397 486 8.63E-10 T 23-10-2018 VMUT_2036 a13fd6f13de75b24292d2a7d8c2c921f 827 Pfam PF02463 RecF/RecN/SMC N terminal domain 5 794 7.7E-17 T 23-10-2018 IPR003395 RecF/RecN/SMC, N-terminal VMUT_2036 a13fd6f13de75b24292d2a7d8c2c921f 827 SUPERFAMILY SSF52540 3 794 4.14E-23 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_2036 a13fd6f13de75b24292d2a7d8c2c921f 827 Gene3D G3DSA:3.40.50.300 560 804 6.5E-19 T 23-10-2018 VMUT_2036 a13fd6f13de75b24292d2a7d8c2c921f 827 Gene3D G3DSA:3.40.50.300 3 339 5.2E-29 T 23-10-2018 VMUT_1918 13a299304bff3a62b8f670c819d2ea3e 75 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 12 45 2.7E-10 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VMUT_1918 13a299304bff3a62b8f670c819d2ea3e 75 Gene3D G3DSA:2.10.260.10 10 42 3.6E-8 T 23-10-2018 VMUT_1918 13a299304bff3a62b8f670c819d2ea3e 75 SMART SM00966 4 49 4.7E-6 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VMUT_1918 13a299304bff3a62b8f670c819d2ea3e 75 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 12 47 3.9E-9 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VMUT_1918 13a299304bff3a62b8f670c819d2ea3e 75 SUPERFAMILY SSF89447 11 65 1.2E-10 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily VMUT_1521 af9db4ba54ed5436bc9435f4d17a5c22 573 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 425 444 - T 23-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 VMUT_1521 af9db4ba54ed5436bc9435f4d17a5c22 573 Gene3D G3DSA:3.40.50.970 366 559 1.1E-56 T 23-10-2018 VMUT_1521 af9db4ba54ed5436bc9435f4d17a5c22 573 Gene3D G3DSA:3.40.50.1220 186 365 2.5E-57 T 23-10-2018 VMUT_1521 af9db4ba54ed5436bc9435f4d17a5c22 573 SUPERFAMILY SSF52467 156 357 1.14E-53 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily VMUT_1521 af9db4ba54ed5436bc9435f4d17a5c22 573 SUPERFAMILY SSF52518 366 562 1.73E-57 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold VMUT_1521 af9db4ba54ed5436bc9435f4d17a5c22 573 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 172 2.6E-53 T 23-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 VMUT_1521 af9db4ba54ed5436bc9435f4d17a5c22 573 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 9 560 2.4E-189 T 23-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 VMUT_1521 af9db4ba54ed5436bc9435f4d17a5c22 573 SUPERFAMILY SSF52518 5 173 2.64E-55 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold VMUT_1521 af9db4ba54ed5436bc9435f4d17a5c22 573 Gene3D G3DSA:3.40.50.970 3 184 2.0E-62 T 23-10-2018 VMUT_1521 af9db4ba54ed5436bc9435f4d17a5c22 573 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 327 1.0E-42 T 23-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 VMUT_1521 af9db4ba54ed5436bc9435f4d17a5c22 573 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 388 536 6.1E-42 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 VMUT_2173 d72afff402c8ee2571990650db507f60 313 Pfam PF13614 AAA domain 3 183 1.6E-16 T 23-10-2018 IPR025669 AAA domain VMUT_2173 d72afff402c8ee2571990650db507f60 313 Gene3D G3DSA:3.40.50.300 2 258 9.2E-33 T 23-10-2018 VMUT_2173 d72afff402c8ee2571990650db507f60 313 SUPERFAMILY SSF52540 1 246 1.5E-24 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1239 742cdc8a67f19b57473f660e77745316 291 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 112 287 1.4E-24 T 23-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 VMUT_1239 742cdc8a67f19b57473f660e77745316 291 SUPERFAMILY SSF56529 73 287 2.22E-33 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VMUT_1239 742cdc8a67f19b57473f660e77745316 291 Gene3D G3DSA:3.10.330.40 1 70 5.1E-6 T 23-10-2018 VMUT_1239 742cdc8a67f19b57473f660e77745316 291 Gene3D G3DSA:3.90.850.10 71 290 2.1E-76 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VMUT_1597 39c6461c799051057812eb917b830851 312 SUPERFAMILY SSF64182 22 290 4.84E-14 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily VMUT_1597 39c6461c799051057812eb917b830851 312 Gene3D G3DSA:3.10.310.30 218 277 2.4E-5 T 23-10-2018 VMUT_1247 4ccfd6b83ebd4d15d05661b58f8e3114 328 Gene3D G3DSA:3.40.50.720 3 327 8.7E-66 T 23-10-2018 VMUT_1247 4ccfd6b83ebd4d15d05661b58f8e3114 328 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 317 8.2E-38 T 23-10-2018 IPR016040 NAD(P)-binding domain VMUT_1247 4ccfd6b83ebd4d15d05661b58f8e3114 328 SUPERFAMILY SSF51735 1 324 3.08E-63 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1790 8e07e3541a2da4400b0e4a2f2ade1ab0 389 Pfam PF04894 Archaeal Nre, N-terminal 21 267 2.4E-80 T 23-10-2018 IPR006978 Archaeal Nre, N-terminal VMUT_1790 8e07e3541a2da4400b0e4a2f2ade1ab0 389 Pfam PF04895 Archaeal Nre, C-terminal 280 384 1.1E-30 T 23-10-2018 IPR006979 Archaeal Nre, C-terminal VMUT_1790 8e07e3541a2da4400b0e4a2f2ade1ab0 389 Hamap MF_02096 DNA repair protein. 1 387 32.342 T 23-10-2018 IPR033167 Archaeal Nre GO:0006281 VMUT_1395 8bbc421a8db966571f66257327786b9c 329 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 6 253 4.1E-67 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR VMUT_1395 8bbc421a8db966571f66257327786b9c 329 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 5 245 1.1E-33 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR VMUT_1892 40957ece053de70c891a3b495983017e 99 Gene3D G3DSA:3.40.50.1010 1 96 1.4E-22 T 23-10-2018 VMUT_1892 40957ece053de70c891a3b495983017e 99 SUPERFAMILY SSF88723 2 83 6.17E-10 T 23-10-2018 IPR029060 PIN-like domain superfamily VMUT_1325 37fab22ce82961c7d929503bae614751 386 Pfam PF02005 N2,N2-dimethylguanosine tRNA methyltransferase 32 383 1.5E-85 T 23-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 VMUT_1325 37fab22ce82961c7d929503bae614751 386 Gene3D G3DSA:3.40.50.150 5 323 1.5E-84 T 23-10-2018 VMUT_1325 37fab22ce82961c7d929503bae614751 386 SUPERFAMILY SSF53335 7 383 2.76E-87 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_1325 37fab22ce82961c7d929503bae614751 386 Gene3D G3DSA:3.30.56.70 330 385 4.2E-8 T 23-10-2018 VMUT_0918 c18b25e9dbb01f5658828c2f96cef8ad 510 Gene3D G3DSA:3.60.20.40 341 509 2.4E-38 T 23-10-2018 VMUT_0918 c18b25e9dbb01f5658828c2f96cef8ad 510 SUPERFAMILY SSF56235 8 509 2.7E-136 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VMUT_0918 c18b25e9dbb01f5658828c2f96cef8ad 510 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 253 272 3.9E-43 T 23-10-2018 VMUT_0918 c18b25e9dbb01f5658828c2f96cef8ad 510 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 224 240 3.9E-43 T 23-10-2018 VMUT_0918 c18b25e9dbb01f5658828c2f96cef8ad 510 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 339 357 3.9E-43 T 23-10-2018 VMUT_0918 c18b25e9dbb01f5658828c2f96cef8ad 510 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 363 381 3.9E-43 T 23-10-2018 VMUT_0918 c18b25e9dbb01f5658828c2f96cef8ad 510 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 129 148 3.9E-43 T 23-10-2018 VMUT_0918 c18b25e9dbb01f5658828c2f96cef8ad 510 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 392 407 3.9E-43 T 23-10-2018 VMUT_0918 c18b25e9dbb01f5658828c2f96cef8ad 510 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 111 129 3.9E-43 T 23-10-2018 VMUT_0918 c18b25e9dbb01f5658828c2f96cef8ad 510 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 40 65 3.9E-43 T 23-10-2018 VMUT_0918 c18b25e9dbb01f5658828c2f96cef8ad 510 Pfam PF01019 Gamma-glutamyltranspeptidase 33 463 2.1E-116 T 23-10-2018 VMUT_0918 c18b25e9dbb01f5658828c2f96cef8ad 510 Gene3D G3DSA:1.10.246.130 240 340 5.7E-18 T 23-10-2018 VMUT_0576 1a7be16f8f2f4cc328e70ff592463cf7 230 PIRSF PIRSF000239 1 221 1.2E-73 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 VMUT_0576 1a7be16f8f2f4cc328e70ff592463cf7 230 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 158 200 4.4E-10 T 23-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 VMUT_0576 1a7be16f8f2f4cc328e70ff592463cf7 230 SUPERFAMILY SSF52833 4 212 4.32E-63 T 23-10-2018 IPR036249 Thioredoxin-like superfamily VMUT_0576 1a7be16f8f2f4cc328e70ff592463cf7 230 Hamap MF_00401 Peroxiredoxin. 6 213 49.037 T 23-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 VMUT_0576 1a7be16f8f2f4cc328e70ff592463cf7 230 Pfam PF00578 AhpC/TSA family 8 137 5.1E-27 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 VMUT_0576 1a7be16f8f2f4cc328e70ff592463cf7 230 Gene3D G3DSA:3.30.1020.20 145 230 6.4E-29 T 23-10-2018 VMUT_0576 1a7be16f8f2f4cc328e70ff592463cf7 230 Gene3D G3DSA:3.40.30.10 3 144 8.0E-41 T 23-10-2018 VMUT_1789 e689f4bc4ff78852f862e7b6849c9026 221 Pfam PF06168 Protein of unknown function (DUF981) 1 207 1.4E-59 T 23-10-2018 IPR009324 Protein of unknown function DUF981 VMUT_2344 758a0a5986cc5c18be573ef8d02557c8 94 Gene3D G3DSA:3.30.110.40 17 94 1.0E-26 T 23-10-2018 IPR036868 TusA-like domain superfamily VMUT_2344 758a0a5986cc5c18be573ef8d02557c8 94 SUPERFAMILY SSF64307 18 92 1.18E-24 T 23-10-2018 IPR036868 TusA-like domain superfamily VMUT_2344 758a0a5986cc5c18be573ef8d02557c8 94 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 25 49 - T 23-10-2018 IPR001455 TusA-like domain VMUT_2344 758a0a5986cc5c18be573ef8d02557c8 94 Pfam PF01206 Sulfurtransferase TusA 23 92 1.1E-22 T 23-10-2018 IPR001455 TusA-like domain VMUT_1058 ee982027a96abcd27714b76a8cd058e3 517 Pfam PF13440 Polysaccharide biosynthesis protein 32 328 4.8E-15 T 23-10-2018 VMUT_2061 ca461ff283fac2f2124a87019f7e3802 103 Hamap MF_00481 50S ribosomal protein L30e [rpl30e]. 2 99 25.732 T 23-10-2018 IPR000231 Ribosomal protein L30e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_2061 ca461ff283fac2f2124a87019f7e3802 103 SUPERFAMILY SSF55315 3 96 1.99E-28 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like VMUT_2061 ca461ff283fac2f2124a87019f7e3802 103 Gene3D G3DSA:3.30.1330.30 1 101 1.2E-38 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like VMUT_2061 ca461ff283fac2f2124a87019f7e3802 103 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 4 95 2.1E-19 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 VMUT_2191 387dfc8af93c6e67e12c7dc3093fa1a6 337 Gene3D G3DSA:1.10.3720.10 89 330 1.1E-19 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_2191 387dfc8af93c6e67e12c7dc3093fa1a6 337 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 335 9.6E-45 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VMUT_2191 387dfc8af93c6e67e12c7dc3093fa1a6 337 SUPERFAMILY SSF161098 96 321 1.64E-16 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_0314 63eb9ca3ddc1147b55b48894d1dcfa43 612 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 586 597 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_0314 63eb9ca3ddc1147b55b48894d1dcfa43 612 Gene3D G3DSA:3.30.70.20 543 606 1.7E-9 T 23-10-2018 VMUT_0314 63eb9ca3ddc1147b55b48894d1dcfa43 612 Gene3D G3DSA:3.40.50.620 204 413 7.9E-51 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_0314 63eb9ca3ddc1147b55b48894d1dcfa43 612 SUPERFAMILY SSF54862 547 598 2.56E-12 T 23-10-2018 VMUT_0314 63eb9ca3ddc1147b55b48894d1dcfa43 612 SUPERFAMILY SSF52402 206 395 7.45E-45 T 23-10-2018 VMUT_0314 63eb9ca3ddc1147b55b48894d1dcfa43 612 Pfam PF00037 4Fe-4S binding domain 580 597 6.0E-5 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_0314 63eb9ca3ddc1147b55b48894d1dcfa43 612 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 234 406 6.2E-40 T 23-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 VMUT_1702 3dcab8f9a41d4fc0ac0f2adc6ebb406c 457 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 314 390 3.6E-7 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal VMUT_1702 3dcab8f9a41d4fc0ac0f2adc6ebb406c 457 Pfam PF07282 Putative transposase DNA-binding domain 363 429 1.2E-18 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal VMUT_1702 3dcab8f9a41d4fc0ac0f2adc6ebb406c 457 Pfam PF01385 Probable transposase 205 348 1.2E-35 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 VMUT_2075 7bd6ed4e98bb4914e9b7378ecf632f46 144 Pfam PF02635 DsrE/DsrF-like family 1 140 1.9E-5 T 23-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein VMUT_2075 7bd6ed4e98bb4914e9b7378ecf632f46 144 Gene3D G3DSA:3.40.1260.10 1 143 6.0E-19 T 23-10-2018 IPR027396 DsrEFH-like VMUT_2075 7bd6ed4e98bb4914e9b7378ecf632f46 144 SUPERFAMILY SSF75169 1 122 2.16E-8 T 23-10-2018 IPR027396 DsrEFH-like VMUT_0326 2ca1946a133ab7d79ff8039c1b733dd3 517 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 282 464 6.8E-23 T 23-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 VMUT_0326 2ca1946a133ab7d79ff8039c1b733dd3 517 SUPERFAMILY SSF53067 11 272 4.8E-58 T 23-10-2018 VMUT_0326 2ca1946a133ab7d79ff8039c1b733dd3 517 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 15 22 - T 23-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 VMUT_0326 2ca1946a133ab7d79ff8039c1b733dd3 517 PIRSF PIRSF000538 9 516 6.3E-101 T 23-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 VMUT_0326 2ca1946a133ab7d79ff8039c1b733dd3 517 SUPERFAMILY SSF53067 272 510 8.64E-52 T 23-10-2018 VMUT_0326 2ca1946a133ab7d79ff8039c1b733dd3 517 Gene3D G3DSA:3.30.420.40 271 516 1.7E-58 T 23-10-2018 VMUT_0326 2ca1946a133ab7d79ff8039c1b733dd3 517 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 11 264 1.6E-41 T 23-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 VMUT_0326 2ca1946a133ab7d79ff8039c1b733dd3 517 Gene3D G3DSA:3.30.420.40 6 270 1.9E-68 T 23-10-2018 VMUT_2307 8f77286b57b1851fa6ca5a6030fab7ce 513 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 263 270 - T 23-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 VMUT_2307 8f77286b57b1851fa6ca5a6030fab7ce 513 Gene3D G3DSA:3.40.309.10 268 461 1.6E-168 T 23-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VMUT_2307 8f77286b57b1851fa6ca5a6030fab7ce 513 Pfam PF00171 Aldehyde dehydrogenase family 29 491 7.9E-164 T 23-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VMUT_2307 8f77286b57b1851fa6ca5a6030fab7ce 513 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 291 302 - T 23-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 VMUT_2307 8f77286b57b1851fa6ca5a6030fab7ce 513 Gene3D G3DSA:3.40.605.10 21 489 1.6E-168 T 23-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VMUT_2307 8f77286b57b1851fa6ca5a6030fab7ce 513 SUPERFAMILY SSF53720 9 494 4.58E-164 T 23-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VMUT_1905 555438b471ff2ec8b6daffb4df665bf9 283 SUPERFAMILY SSF52540 7 227 1.2E-54 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1905 555438b471ff2ec8b6daffb4df665bf9 283 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VMUT_1905 555438b471ff2ec8b6daffb4df665bf9 283 Gene3D G3DSA:3.40.50.300 1 229 7.3E-55 T 23-10-2018 VMUT_1905 555438b471ff2ec8b6daffb4df665bf9 283 SMART SM00382 32 219 1.8E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_1905 555438b471ff2ec8b6daffb4df665bf9 283 Pfam PF00005 ABC transporter 25 164 4.9E-24 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_0014 2f5bd0c071272df18c29593831885ced 359 Gene3D G3DSA:3.40.50.1820 2 356 1.6E-85 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold VMUT_0014 2f5bd0c071272df18c29593831885ced 359 SUPERFAMILY SSF53474 49 354 4.93E-23 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold VMUT_0014 2f5bd0c071272df18c29593831885ced 359 Pfam PF12697 Alpha/beta hydrolase family 52 280 2.2E-7 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VMUT_2114 c51cd0365492354669529ff6dc4687ae 190 Pfam PF04266 ASCH domain 29 102 5.7E-7 T 23-10-2018 IPR007374 ASCH domain VMUT_2114 c51cd0365492354669529ff6dc4687ae 190 SUPERFAMILY SSF88697 7 100 3.73E-13 T 23-10-2018 IPR015947 PUA-like superfamily VMUT_2114 c51cd0365492354669529ff6dc4687ae 190 SMART SM01022 11 108 6.2E-8 T 23-10-2018 IPR007374 ASCH domain VMUT_1378 ad7f24b3ca52ecd52a3ebf1829453e24 256 Gene3D G3DSA:3.90.226.10 3 198 2.8E-54 T 23-10-2018 VMUT_1378 ad7f24b3ca52ecd52a3ebf1829453e24 256 Gene3D G3DSA:1.10.12.10 199 255 3.4E-19 T 23-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal VMUT_1378 ad7f24b3ca52ecd52a3ebf1829453e24 256 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 23-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 VMUT_1378 ad7f24b3ca52ecd52a3ebf1829453e24 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 253 4.4E-53 T 23-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VMUT_1378 ad7f24b3ca52ecd52a3ebf1829453e24 256 SUPERFAMILY SSF52096 1 255 2.49E-71 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VMUT_2218 a88bc412ab2ddec3fa282e9013322c57 249 Pfam PF12706 Beta-lactamase superfamily domain 30 219 3.9E-23 T 23-10-2018 IPR001279 Metallo-beta-lactamase VMUT_2218 a88bc412ab2ddec3fa282e9013322c57 249 SMART SM00849 18 196 4.0E-5 T 23-10-2018 IPR001279 Metallo-beta-lactamase VMUT_2218 a88bc412ab2ddec3fa282e9013322c57 249 SUPERFAMILY SSF56281 2 222 1.31E-50 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_2218 a88bc412ab2ddec3fa282e9013322c57 249 Gene3D G3DSA:3.60.15.10 2 230 2.3E-51 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_1311 382f47ce34ab14796a0a32e2fe4bcf96 412 Gene3D G3DSA:3.20.20.70 34 335 1.2E-63 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_1311 382f47ce34ab14796a0a32e2fe4bcf96 412 PIRSF PIRSF037420 22 383 7.0E-105 T 23-10-2018 IPR017200 Coenzyme PQQ synthesis protein E VMUT_1311 382f47ce34ab14796a0a32e2fe4bcf96 412 SMART SM00729 36 236 1.1E-5 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VMUT_1311 382f47ce34ab14796a0a32e2fe4bcf96 412 SUPERFAMILY SSF102114 37 357 4.19E-76 T 23-10-2018 VMUT_1311 382f47ce34ab14796a0a32e2fe4bcf96 412 Pfam PF13353 4Fe-4S single cluster domain 43 123 6.5E-8 T 23-10-2018 VMUT_1311 382f47ce34ab14796a0a32e2fe4bcf96 412 Pfam PF04055 Radical SAM superfamily 41 195 4.7E-25 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_1311 382f47ce34ab14796a0a32e2fe4bcf96 412 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 285 376 3.2E-14 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain VMUT_1311 382f47ce34ab14796a0a32e2fe4bcf96 412 Pfam PF13186 Iron-sulfur cluster-binding domain 285 350 9.2E-11 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain VMUT_0652 40aacdb3c9cf848bacbbd913af0609c0 490 Gene3D G3DSA:3.90.1860.10 7 490 6.2E-195 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 VMUT_0652 40aacdb3c9cf848bacbbd913af0609c0 490 Pfam PF01139 tRNA-splicing ligase RtcB 53 490 8.4E-156 T 23-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 VMUT_0652 40aacdb3c9cf848bacbbd913af0609c0 490 SUPERFAMILY SSF103365 11 490 1.05E-166 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 VMUT_0521 c352ca6a7baa5199b822ca765f370ca3 288 SUPERFAMILY SSF46785 32 86 6.71E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_1001 9201cf47d24e6b057099ed036873c511 697 Pfam PF01935 Domain of unknown function DUF87 381 438 4.2E-13 T 23-10-2018 IPR002789 Helicase HerA, central domain VMUT_1001 9201cf47d24e6b057099ed036873c511 697 SUPERFAMILY SSF52540 351 655 3.14E-28 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0294 fb7ac3169566be92653d943d49b4adfb 343 Gene3D G3DSA:3.40.50.11850 101 231 2.5E-39 T 23-10-2018 VMUT_0294 fb7ac3169566be92653d943d49b4adfb 343 Gene3D G3DSA:3.40.50.11860 232 328 2.5E-39 T 23-10-2018 VMUT_0294 fb7ac3169566be92653d943d49b4adfb 343 TIGRFAM TIGR00322 diphth2_R: diphthamide biosynthesis enzyme Dph1/Dph2 domain 16 330 5.5E-65 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 VMUT_0294 fb7ac3169566be92653d943d49b4adfb 343 Gene3D G3DSA:3.40.50.11840 29 100 2.5E-39 T 23-10-2018 VMUT_0294 fb7ac3169566be92653d943d49b4adfb 343 Pfam PF01866 Putative diphthamide synthesis protein 38 327 4.0E-34 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 VMUT_0294 fb7ac3169566be92653d943d49b4adfb 343 PIRSF PIRSF004967 6 335 4.3E-50 T 23-10-2018 IPR035435 Diphthamide synthesis DHP1/DPH2, eukaryotes and archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 VMUT_0195 f1270b20facf38939f4bf515445dd98c 330 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 185 324 4.7E-33 T 23-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 VMUT_0195 f1270b20facf38939f4bf515445dd98c 330 SUPERFAMILY SSF51735 6 171 7.28E-50 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0195 f1270b20facf38939f4bf515445dd98c 330 Gene3D G3DSA:3.40.50.720 1 178 6.3E-61 T 23-10-2018 VMUT_0195 f1270b20facf38939f4bf515445dd98c 330 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 323 1.2E-76 T 23-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 VMUT_0195 f1270b20facf38939f4bf515445dd98c 330 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 13 171 5.0E-56 T 23-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 VMUT_0195 f1270b20facf38939f4bf515445dd98c 330 SUPERFAMILY SSF48179 185 321 1.19E-23 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VMUT_0195 f1270b20facf38939f4bf515445dd98c 330 Gene3D G3DSA:1.10.3730.40 183 330 6.3E-39 T 23-10-2018 VMUT_0095 bb12940e1ff90b2b89536d98d325595e 428 Gene3D G3DSA:3.90.1150.10 280 423 4.4E-51 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VMUT_0095 bb12940e1ff90b2b89536d98d325595e 428 PIRSF PIRSF000412 1 420 2.2E-141 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 VMUT_0095 bb12940e1ff90b2b89536d98d325595e 428 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 219 235 - T 23-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 VMUT_0095 bb12940e1ff90b2b89536d98d325595e 428 SUPERFAMILY SSF53383 10 408 1.38E-127 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VMUT_0095 bb12940e1ff90b2b89536d98d325595e 428 Pfam PF00464 Serine hydroxymethyltransferase 8 382 4.8E-76 T 23-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 VMUT_0095 bb12940e1ff90b2b89536d98d325595e 428 Gene3D G3DSA:3.40.640.10 33 279 2.4E-77 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VMUT_0095 bb12940e1ff90b2b89536d98d325595e 428 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 410 39.247 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 VMUT_0292 0b7344e807ed83969b73026b071f9bcd 130 Pfam PF02675 S-adenosylmethionine decarboxylase 19 127 2.2E-32 T 23-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 VMUT_0292 0b7344e807ed83969b73026b071f9bcd 130 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 14 128 3.9E-36 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 VMUT_0292 0b7344e807ed83969b73026b071f9bcd 130 SUPERFAMILY SSF56276 15 128 1.88E-32 T 23-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 VMUT_0292 0b7344e807ed83969b73026b071f9bcd 130 Hamap MF_01298 Arginine decarboxylase proenzyme. 5 129 46.793 T 23-10-2018 IPR027549 Arginine decarboxylase proenzyme GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 VMUT_0292 0b7344e807ed83969b73026b071f9bcd 130 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 13 130 26.174 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 VMUT_0292 0b7344e807ed83969b73026b071f9bcd 130 Gene3D G3DSA:3.60.90.10 5 130 3.9E-33 T 23-10-2018 VMUT_1520 2933f36f5cf8df8bbccddd865321a867 347 Gene3D G3DSA:1.10.238.260 243 347 1.3E-36 T 23-10-2018 VMUT_1520 2933f36f5cf8df8bbccddd865321a867 347 Gene3D G3DSA:3.20.20.70 1 239 6.4E-88 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_1520 2933f36f5cf8df8bbccddd865321a867 347 Pfam PF00682 HMGL-like 1 236 1.6E-78 T 23-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 VMUT_1520 2933f36f5cf8df8bbccddd865321a867 347 SUPERFAMILY SSF51569 2 254 2.75E-83 T 23-10-2018 VMUT_1520 2933f36f5cf8df8bbccddd865321a867 347 TIGRFAM TIGR02090 LEU1_arch: isopropylmalate/citramalate/homocitrate synthases 2 341 1.5E-147 T 23-10-2018 IPR011830 Isopropylmalate/citramalate/homocitrate synthase GO:0019752|GO:0046912 VMUT_1520 2933f36f5cf8df8bbccddd865321a867 347 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 165 178 - T 23-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 VMUT_1911 a4b14e06b59597dc537950d46d1a55dd 321 SUPERFAMILY SSF51735 5 317 4.48E-81 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1911 a4b14e06b59597dc537950d46d1a55dd 321 Gene3D G3DSA:3.30.1780.10 20 304 8.6E-87 T 23-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 VMUT_1911 a4b14e06b59597dc537950d46d1a55dd 321 PIRSF PIRSF001439 1 317 2.5E-72 T 23-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 VMUT_1911 a4b14e06b59597dc537950d46d1a55dd 321 Gene3D G3DSA:3.40.50.720 119 289 8.6E-87 T 23-10-2018 VMUT_1911 a4b14e06b59597dc537950d46d1a55dd 321 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 9 307 1.1E-64 T 23-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 VMUT_1801 3f5ce2da8b15580e3d3b8e62f6806d24 113 Pfam PF11419 Protein of unknown function (DUF3194) 7 75 3.2E-6 T 23-10-2018 IPR024502 Protein of unknown function DUF3194 VMUT_1801 3f5ce2da8b15580e3d3b8e62f6806d24 113 Gene3D G3DSA:3.30.300.100 1 87 4.0E-7 T 23-10-2018 IPR035954 MTH677-like superfamily VMUT_0788 e1c2822e7fd82c0e861786c05c12f838 497 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 347 473 2.0E-26 T 23-10-2018 VMUT_0788 e1c2822e7fd82c0e861786c05c12f838 497 Pfam PF03601 Conserved hypothetical protein 698 159 464 1.6E-21 T 23-10-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 VMUT_0913 d56954960297fadce5e8abe4f3088699 179 SMART SM00530 92 147 1.6E-9 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VMUT_0913 d56954960297fadce5e8abe4f3088699 179 Gene3D G3DSA:1.10.260.40 79 179 2.0E-18 T 23-10-2018 VMUT_0913 d56954960297fadce5e8abe4f3088699 179 TIGRFAM TIGR00270 TIGR00270: TIGR00270 family protein 4 171 5.4E-28 T 23-10-2018 IPR004451 Conserved hypothetical protein CHP00270 VMUT_0913 d56954960297fadce5e8abe4f3088699 179 Pfam PF01381 Helix-turn-helix 93 144 6.1E-12 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VMUT_0913 d56954960297fadce5e8abe4f3088699 179 SUPERFAMILY SSF47413 88 144 7.17E-13 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VMUT_1404 e057de8748d2c24038ba142dd9c7a9e6 333 SUPERFAMILY SSF52540 9 260 4.51E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1404 e057de8748d2c24038ba142dd9c7a9e6 333 Gene3D G3DSA:3.40.50.300 8 182 4.0E-23 T 23-10-2018 VMUT_1404 e057de8748d2c24038ba142dd9c7a9e6 333 Gene3D G3DSA:1.10.8.60 183 260 2.1E-24 T 23-10-2018 VMUT_1404 e057de8748d2c24038ba142dd9c7a9e6 333 Pfam PF01637 ATPase domain predominantly from Archaea 21 222 1.8E-12 T 23-10-2018 IPR011579 ATPase domain GO:0005524 VMUT_1786 98fe82c3ef159eedf5682d73b48790a0 238 Gene3D G3DSA:3.40.1180.10 1 238 2.8E-84 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 VMUT_1786 98fe82c3ef159eedf5682d73b48790a0 238 SUPERFAMILY SSF64005 3 233 2.35E-70 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 VMUT_1786 98fe82c3ef159eedf5682d73b48790a0 238 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 183 200 - T 23-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 VMUT_1786 98fe82c3ef159eedf5682d73b48790a0 238 Pfam PF01255 Putative undecaprenyl diphosphate synthase 12 237 1.1E-69 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 VMUT_1786 98fe82c3ef159eedf5682d73b48790a0 238 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 5 238 36.597 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 VMUT_1786 98fe82c3ef159eedf5682d73b48790a0 238 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 5 237 8.8E-67 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 VMUT_1268 b0e3ddcec6c6f93e662cdfbb421e92b5 603 Gene3D G3DSA:2.40.50.100 120 192 2.7E-155 T 23-10-2018 VMUT_1268 b0e3ddcec6c6f93e662cdfbb421e92b5 603 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 3 594 48.91 T 23-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 VMUT_1268 b0e3ddcec6c6f93e662cdfbb421e92b5 603 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 219 442 4.3E-79 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VMUT_1268 b0e3ddcec6c6f93e662cdfbb421e92b5 603 SUPERFAMILY SSF52540 185 447 7.24E-76 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1268 b0e3ddcec6c6f93e662cdfbb421e92b5 603 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 85 210 5.8E-41 T 23-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 VMUT_1268 b0e3ddcec6c6f93e662cdfbb421e92b5 603 SUPERFAMILY SSF47917 455 560 5.49E-24 T 23-10-2018 VMUT_1268 b0e3ddcec6c6f93e662cdfbb421e92b5 603 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 8 69 3.6E-11 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VMUT_1268 b0e3ddcec6c6f93e662cdfbb421e92b5 603 Gene3D G3DSA:3.40.50.300 75 442 2.7E-155 T 23-10-2018 VMUT_1268 b0e3ddcec6c6f93e662cdfbb421e92b5 603 Gene3D G3DSA:1.10.1140.10 443 595 4.7E-41 T 23-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VMUT_1268 b0e3ddcec6c6f93e662cdfbb421e92b5 603 Gene3D G3DSA:2.40.30.20 3 72 8.4E-27 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VMUT_1268 b0e3ddcec6c6f93e662cdfbb421e92b5 603 SUPERFAMILY SSF50615 4 72 3.88E-10 T 23-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VMUT_0145 6cb697d143dc8ad0a2ec0ea07692d242 229 SUPERFAMILY SSF53448 3 225 2.5E-63 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0145 6cb697d143dc8ad0a2ec0ea07692d242 229 Gene3D G3DSA:3.90.550.10 2 228 1.1E-64 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0145 6cb697d143dc8ad0a2ec0ea07692d242 229 Pfam PF00483 Nucleotidyl transferase 4 223 4.0E-35 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 VMUT_0168 6bb7c1fb648ea734905f257facbfe279 295 Pfam PF04321 RmlD substrate binding domain 28 282 7.6E-57 T 23-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 VMUT_0168 6bb7c1fb648ea734905f257facbfe279 295 SUPERFAMILY SSF51735 1 285 3.96E-62 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0168 6bb7c1fb648ea734905f257facbfe279 295 Gene3D G3DSA:3.40.50.720 4 263 7.2E-69 T 23-10-2018 VMUT_0168 6bb7c1fb648ea734905f257facbfe279 295 Gene3D G3DSA:3.90.25.10 166 257 7.2E-69 T 23-10-2018 VMUT_2332 95c23ceb342bf4f492c60d0a7ec22b46 368 SUPERFAMILY SSF54001 228 323 8.99E-7 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily VMUT_2332 95c23ceb342bf4f492c60d0a7ec22b46 368 Pfam PF01841 Transglutaminase-like superfamily 242 320 5.8E-8 T 23-10-2018 IPR002931 Transglutaminase-like VMUT_1077 36fd11d31de37f2b272e0e7932271625 124 Gene3D G3DSA:3.40.50.2000 7 124 1.1E-20 T 23-10-2018 VMUT_1077 36fd11d31de37f2b272e0e7932271625 124 Pfam PF00534 Glycosyl transferases group 1 41 121 2.7E-15 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 VMUT_1077 36fd11d31de37f2b272e0e7932271625 124 SUPERFAMILY SSF53756 19 120 2.77E-22 T 23-10-2018 VMUT_1703 1c50efd56b05388ac61ba952d67d5d4c 52 SUPERFAMILY SSF46785 2 48 1.29E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_1703 1c50efd56b05388ac61ba952d67d5d4c 52 Gene3D G3DSA:1.10.10.10 1 50 4.0E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_0477 90722686db6f5bb67adf3fbfe614de4a 316 Pfam PF01925 Sulfite exporter TauE/SafE 32 303 9.1E-34 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 VMUT_1993 55dc8a83235b4029bf5fa44b29c873e8 236 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 41 219 2.5E-15 T 23-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 VMUT_1993 55dc8a83235b4029bf5fa44b29c873e8 236 Pfam PF02592 Putative vitamin uptake transporter 68 212 1.4E-23 T 23-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 VMUT_0240 6e2f4395c282e0efab947f2da2dc1427 592 SUPERFAMILY SSF50692 489 588 1.7E-8 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily VMUT_0240 6e2f4395c282e0efab947f2da2dc1427 592 Gene3D G3DSA:3.40.50.740 55 426 2.5E-70 T 23-10-2018 VMUT_0240 6e2f4395c282e0efab947f2da2dc1427 592 SUPERFAMILY SSF53706 5 507 7.59E-75 T 23-10-2018 VMUT_0240 6e2f4395c282e0efab947f2da2dc1427 592 Gene3D G3DSA:3.40.228.10 114 312 2.5E-70 T 23-10-2018 VMUT_0240 6e2f4395c282e0efab947f2da2dc1427 592 Gene3D G3DSA:3.30.2070.10 383 462 2.5E-70 T 23-10-2018 VMUT_0240 6e2f4395c282e0efab947f2da2dc1427 592 Pfam PF00384 Molybdopterin oxidoreductase 324 391 4.2E-5 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_2251 267f00c6223151f16fa1e8a8005e5d0e 788 Pfam PF01804 Penicillin amidase 17 622 6.6E-98 T 23-10-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 VMUT_2251 267f00c6223151f16fa1e8a8005e5d0e 788 SUPERFAMILY SSF56235 15 622 1.13E-101 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VMUT_2251 267f00c6223151f16fa1e8a8005e5d0e 788 PIRSF PIRSF001227 28 625 3.2E-99 T 23-10-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 VMUT_2251 267f00c6223151f16fa1e8a8005e5d0e 788 Gene3D G3DSA:1.10.1400.10 392 534 2.9E-80 T 23-10-2018 VMUT_2251 267f00c6223151f16fa1e8a8005e5d0e 788 Gene3D G3DSA:2.30.120.10 179 241 2.9E-80 T 23-10-2018 VMUT_2251 267f00c6223151f16fa1e8a8005e5d0e 788 Gene3D G3DSA:3.60.20.10 109 615 2.9E-80 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VMUT_0397 c0943b4ba24524a623b197d822c53606 304 SUPERFAMILY SSF52518 19 302 3.93E-77 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold VMUT_0397 c0943b4ba24524a623b197d822c53606 304 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 52 207 4.1E-22 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 VMUT_0397 c0943b4ba24524a623b197d822c53606 304 Gene3D G3DSA:3.40.50.970 5 96 3.7E-6 T 23-10-2018 VMUT_0397 c0943b4ba24524a623b197d822c53606 304 Gene3D G3DSA:3.40.50.970 97 302 3.7E-68 T 23-10-2018 VMUT_0541 cf7628012631205bf957b3b286869179 318 Pfam PF02754 Cysteine-rich domain 212 295 0.0011 T 23-10-2018 IPR004017 Cysteine-rich domain VMUT_0666 a58bf75a235c56d57d08106ffd86ae79 219 TIGRFAM TIGR01508 rib_reduct_arch: diaminohydroxyphosphoribosylaminopyrimidine reductase 4 213 4.2E-73 T 23-10-2018 IPR006401 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal GO:0016491|GO:0055114 KEGG: 00740+1.1.1.302|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VMUT_0666 a58bf75a235c56d57d08106ffd86ae79 219 SUPERFAMILY SSF53597 2 207 3.23E-57 T 23-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 VMUT_0666 a58bf75a235c56d57d08106ffd86ae79 219 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 3 215 1.9E-58 T 23-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 VMUT_0666 a58bf75a235c56d57d08106ffd86ae79 219 Gene3D G3DSA:3.40.430.10 2 218 3.0E-66 T 23-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 VMUT_0666 a58bf75a235c56d57d08106ffd86ae79 219 Pfam PF01872 RibD C-terminal domain 4 212 9.2E-54 T 23-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 VMUT_1360 5de672490d63956fc212f05806a1fb47 464 Gene3D G3DSA:3.30.465.40 5 241 8.3E-58 T 23-10-2018 VMUT_1360 5de672490d63956fc212f05806a1fb47 464 Gene3D G3DSA:3.40.462.40 271 415 2.6E-31 T 23-10-2018 VMUT_1360 5de672490d63956fc212f05806a1fb47 464 SUPERFAMILY SSF55103 231 456 3.76E-32 T 23-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 VMUT_1360 5de672490d63956fc212f05806a1fb47 464 SUPERFAMILY SSF56176 2 227 1.72E-53 T 23-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VMUT_1360 5de672490d63956fc212f05806a1fb47 464 Pfam PF01565 FAD binding domain 49 188 6.4E-37 T 23-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 VMUT_1360 5de672490d63956fc212f05806a1fb47 464 Pfam PF02913 FAD linked oxidases, C-terminal domain 227 455 8.0E-30 T 23-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 VMUT_0808 1819b4583c5b24b3f37eaf3cabdea2a9 307 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 4 304 3.2E-93 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 VMUT_0808 1819b4583c5b24b3f37eaf3cabdea2a9 307 SMART SM00849 20 272 0.0045 T 23-10-2018 IPR001279 Metallo-beta-lactamase VMUT_0808 1819b4583c5b24b3f37eaf3cabdea2a9 307 Gene3D G3DSA:3.60.15.10 3 305 3.4E-81 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_0808 1819b4583c5b24b3f37eaf3cabdea2a9 307 SUPERFAMILY SSF56281 4 303 1.97E-71 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_0808 1819b4583c5b24b3f37eaf3cabdea2a9 307 Pfam PF12706 Beta-lactamase superfamily domain 31 273 3.1E-14 T 23-10-2018 IPR001279 Metallo-beta-lactamase VMUT_0808 1819b4583c5b24b3f37eaf3cabdea2a9 307 Hamap MF_01818 Ribonuclease BN [rbn]. 3 305 33.783 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 VMUT_0208 21a79a284c503d026495ef92c4045360 149 Gene3D G3DSA:1.10.10.10 14 134 8.7E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_0208 21a79a284c503d026495ef92c4045360 149 SUPERFAMILY SSF46785 32 122 4.63E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0208 21a79a284c503d026495ef92c4045360 149 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 33 104 2.9E-9 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal VMUT_0024 f3309b5c9de40bf3666027cde9517706 477 SUPERFAMILY SSF56801 3 467 1.96E-130 T 23-10-2018 VMUT_0024 f3309b5c9de40bf3666027cde9517706 477 Pfam PF00501 AMP-binding enzyme 12 371 2.0E-76 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VMUT_0024 f3309b5c9de40bf3666027cde9517706 477 Gene3D G3DSA:3.30.300.310 369 469 2.5E-34 T 23-10-2018 VMUT_0024 f3309b5c9de40bf3666027cde9517706 477 ProSitePatterns PS00455 Putative AMP-binding domain signature. 136 147 - T 23-10-2018 IPR020845 AMP-binding, conserved site VMUT_0024 f3309b5c9de40bf3666027cde9517706 477 Gene3D G3DSA:3.40.50.12780 2 368 1.3E-92 T 23-10-2018 VMUT_0024 f3309b5c9de40bf3666027cde9517706 477 Pfam PF13193 AMP-binding enzyme C-terminal domain 380 455 2.3E-20 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VMUT_0264 4d927f47efa650d6443301388a0a77b7 164 Pfam PF00583 Acetyltransferase (GNAT) family 33 129 2.4E-12 T 23-10-2018 IPR000182 GNAT domain VMUT_0264 4d927f47efa650d6443301388a0a77b7 164 Gene3D G3DSA:3.40.630.30 9 153 6.9E-23 T 23-10-2018 VMUT_0264 4d927f47efa650d6443301388a0a77b7 164 SUPERFAMILY SSF55729 10 131 1.1E-20 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase VMUT_0443 3f56e51decb3d4a25930ecd5c94272bd 184 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 156 164 - T 23-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 VMUT_0443 3f56e51decb3d4a25930ecd5c94272bd 184 SMART SM00562 2 182 4.9E-51 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 VMUT_0443 3f56e51decb3d4a25930ecd5c94272bd 184 SUPERFAMILY SSF54919 1 182 5.36E-51 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 VMUT_0443 3f56e51decb3d4a25930ecd5c94272bd 184 Pfam PF00334 Nucleoside diphosphate kinase 95 179 3.3E-22 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 VMUT_0443 3f56e51decb3d4a25930ecd5c94272bd 184 Pfam PF00334 Nucleoside diphosphate kinase 3 53 3.5E-17 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 VMUT_0443 3f56e51decb3d4a25930ecd5c94272bd 184 Gene3D G3DSA:3.30.70.141 1 182 1.0E-72 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 VMUT_0258 35bfdb0b93fa806da21451c7ff459d51 204 SMART SM00934 1 197 3.0E-23 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VMUT_0258 35bfdb0b93fa806da21451c7ff459d51 204 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 4 195 1.8E-20 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VMUT_0258 35bfdb0b93fa806da21451c7ff459d51 204 SUPERFAMILY SSF51366 3 201 2.89E-27 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 VMUT_0258 35bfdb0b93fa806da21451c7ff459d51 204 Gene3D G3DSA:3.20.20.70 1 202 3.4E-60 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_0434 db6149e20d94b56926493e743bc634ce 415 SMART SM01329 28 407 3.1E-172 T 23-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 VMUT_0434 db6149e20d94b56926493e743bc634ce 415 SUPERFAMILY SSF53659 3 411 1.29E-135 T 23-10-2018 VMUT_0434 db6149e20d94b56926493e743bc634ce 415 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 29 406 1.2E-103 T 23-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 VMUT_0434 db6149e20d94b56926493e743bc634ce 415 Gene3D G3DSA:3.40.718.10 4 414 2.1E-164 T 23-10-2018 VMUT_1787 a8db85c3e3bb36cdc47a7e6d8c81290d 388 SUPERFAMILY SSF51735 1 332 1.02E-51 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1787 a8db85c3e3bb36cdc47a7e6d8c81290d 388 Gene3D G3DSA:3.40.50.720 2 293 4.2E-137 T 23-10-2018 VMUT_1787 a8db85c3e3bb36cdc47a7e6d8c81290d 388 Gene3D G3DSA:3.90.25.10 210 373 4.2E-137 T 23-10-2018 VMUT_1787 a8db85c3e3bb36cdc47a7e6d8c81290d 388 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 282 2.2E-21 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 VMUT_1603 ca03b9e44a2f393b1be9effd5b745936 306 SUPERFAMILY SSF53633 3 302 2.23E-73 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily VMUT_1603 ca03b9e44a2f393b1be9effd5b745936 306 PIRSF PIRSF000723 1 304 6.8E-113 T 23-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 VMUT_1603 ca03b9e44a2f393b1be9effd5b745936 306 Gene3D G3DSA:3.40.1160.10 1 304 1.9E-108 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily VMUT_1603 ca03b9e44a2f393b1be9effd5b745936 306 Pfam PF00696 Amino acid kinase family 2 284 1.6E-27 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 VMUT_1603 ca03b9e44a2f393b1be9effd5b745936 306 PRINTS PR01469 Bacterial carbamate kinase signature 103 122 1.6E-48 T 23-10-2018 VMUT_1603 ca03b9e44a2f393b1be9effd5b745936 306 PRINTS PR01469 Bacterial carbamate kinase signature 204 219 1.6E-48 T 23-10-2018 VMUT_1603 ca03b9e44a2f393b1be9effd5b745936 306 PRINTS PR01469 Bacterial carbamate kinase signature 152 171 1.6E-48 T 23-10-2018 VMUT_1603 ca03b9e44a2f393b1be9effd5b745936 306 PRINTS PR01469 Bacterial carbamate kinase signature 259 274 1.6E-48 T 23-10-2018 VMUT_1603 ca03b9e44a2f393b1be9effd5b745936 306 PRINTS PR01469 Bacterial carbamate kinase signature 43 62 1.6E-48 T 23-10-2018 VMUT_1603 ca03b9e44a2f393b1be9effd5b745936 306 PRINTS PR01469 Bacterial carbamate kinase signature 175 193 1.6E-48 T 23-10-2018 VMUT_1309 4b0e7ca8735cfe77e519b4b5715b6172 451 Pfam PF06068 TIP49 C-terminus 15 410 1.0E-151 T 23-10-2018 IPR010339 TIP49, C-terminal GO:0003678|GO:0005524 Reactome: R-HSA-171319|Reactome: R-HSA-3214847 VMUT_1309 4b0e7ca8735cfe77e519b4b5715b6172 451 SMART SM00382 62 360 1.5E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_1309 4b0e7ca8735cfe77e519b4b5715b6172 451 Gene3D G3DSA:1.10.8.60 361 451 2.9E-29 T 23-10-2018 VMUT_1309 4b0e7ca8735cfe77e519b4b5715b6172 451 Gene3D G3DSA:3.40.50.300 19 356 1.2E-96 T 23-10-2018 VMUT_1309 4b0e7ca8735cfe77e519b4b5715b6172 451 Gene3D G3DSA:2.40.50.360 119 245 1.2E-96 T 23-10-2018 VMUT_1309 4b0e7ca8735cfe77e519b4b5715b6172 451 SUPERFAMILY SSF52540 35 446 2.97E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1309 4b0e7ca8735cfe77e519b4b5715b6172 451 SUPERFAMILY SSF50249 125 206 1.64E-18 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold VMUT_1688 df6b9212899efc18003d06276831c018 352 PRINTS PR01270 Histone deacetylase superfamily signature 123 146 2.9E-18 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VMUT_1688 df6b9212899efc18003d06276831c018 352 PRINTS PR01270 Histone deacetylase superfamily signature 241 251 2.9E-18 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VMUT_1688 df6b9212899efc18003d06276831c018 352 PRINTS PR01270 Histone deacetylase superfamily signature 156 171 2.9E-18 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VMUT_1688 df6b9212899efc18003d06276831c018 352 PRINTS PR01271 Histone deacetylase signature 219 237 2.1E-7 T 23-10-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 VMUT_1688 df6b9212899efc18003d06276831c018 352 PRINTS PR01271 Histone deacetylase signature 202 215 2.1E-7 T 23-10-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 VMUT_1688 df6b9212899efc18003d06276831c018 352 PRINTS PR01271 Histone deacetylase signature 23 40 2.1E-7 T 23-10-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 VMUT_1688 df6b9212899efc18003d06276831c018 352 PRINTS PR01271 Histone deacetylase signature 57 75 2.1E-7 T 23-10-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 VMUT_1688 df6b9212899efc18003d06276831c018 352 SUPERFAMILY SSF52768 4 314 1.01E-94 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily VMUT_1688 df6b9212899efc18003d06276831c018 352 Pfam PF00850 Histone deacetylase domain 21 308 1.1E-69 T 23-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VMUT_1688 df6b9212899efc18003d06276831c018 352 Gene3D G3DSA:3.40.800.20 1 332 9.1E-96 T 23-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VMUT_0530 193039c6250bbe5b18ede1085234c5f3 473 Pfam PF08328 Adenylosuccinate lyase C-terminal 322 433 1.6E-29 T 23-10-2018 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 VMUT_0530 193039c6250bbe5b18ede1085234c5f3 473 SUPERFAMILY SSF48557 3 457 5.5E-71 T 23-10-2018 IPR008948 L-Aspartase-like GO:0003824 VMUT_0530 193039c6250bbe5b18ede1085234c5f3 473 PRINTS PR00149 Fumarate lyase superfamily signature 285 301 1.8E-19 T 23-10-2018 IPR000362 Fumarate lyase family VMUT_0530 193039c6250bbe5b18ede1085234c5f3 473 PRINTS PR00149 Fumarate lyase superfamily signature 156 174 1.8E-19 T 23-10-2018 IPR000362 Fumarate lyase family VMUT_0530 193039c6250bbe5b18ede1085234c5f3 473 PRINTS PR00149 Fumarate lyase superfamily signature 244 271 1.8E-19 T 23-10-2018 IPR000362 Fumarate lyase family VMUT_0530 193039c6250bbe5b18ede1085234c5f3 473 PRINTS PR00149 Fumarate lyase superfamily signature 110 128 1.8E-19 T 23-10-2018 IPR000362 Fumarate lyase family VMUT_0530 193039c6250bbe5b18ede1085234c5f3 473 Gene3D G3DSA:1.20.200.10 111 434 6.1E-105 T 23-10-2018 VMUT_0530 193039c6250bbe5b18ede1085234c5f3 473 ProSitePatterns PS00163 Fumarate lyases signature. 285 294 - T 23-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 VMUT_0530 193039c6250bbe5b18ede1085234c5f3 473 Pfam PF00206 Lyase 68 303 1.7E-37 T 23-10-2018 IPR022761 Fumarate lyase, N-terminal VMUT_0530 193039c6250bbe5b18ede1085234c5f3 473 Gene3D G3DSA:1.10.40.30 373 433 6.1E-105 T 23-10-2018 VMUT_0530 193039c6250bbe5b18ede1085234c5f3 473 Gene3D G3DSA:1.10.275.10 1 109 8.9E-26 T 23-10-2018 IPR024083 Fumarase/histidase, N-terminal VMUT_0121 b58d7e6a86ca5a244abdf95a0e8c1042 214 Pfam PF13847 Methyltransferase domain 57 186 1.0E-17 T 23-10-2018 IPR025714 Methyltransferase domain VMUT_0121 b58d7e6a86ca5a244abdf95a0e8c1042 214 SUPERFAMILY SSF53335 17 179 1.63E-31 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_0121 b58d7e6a86ca5a244abdf95a0e8c1042 214 Gene3D G3DSA:3.40.50.150 9 213 3.4E-54 T 23-10-2018 VMUT_0121 b58d7e6a86ca5a244abdf95a0e8c1042 214 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 126 132 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 VMUT_1655 ba80d3a9d876f06c904fa0f3c2931aac 244 Pfam PF07758 Protein of unknown function (DUF1614) 59 235 1.1E-37 T 23-10-2018 IPR011672 Protein of unknown function DUF1614 VMUT_0533 220b7621503b21713c2dc24feca248a7 76 SMART SM00966 5 50 1.9E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VMUT_0533 220b7621503b21713c2dc24feca248a7 76 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 45 8.1E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VMUT_0533 220b7621503b21713c2dc24feca248a7 76 SUPERFAMILY SSF89447 5 68 7.67E-13 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily VMUT_0533 220b7621503b21713c2dc24feca248a7 76 Gene3D G3DSA:2.10.260.10 2 43 7.1E-12 T 23-10-2018 VMUT_0533 220b7621503b21713c2dc24feca248a7 76 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 6 47 3.9E-11 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VMUT_1018 28a9ea8ae11ac4668d047efddab4a06a 106 Pfam PF01402 Ribbon-helix-helix protein, copG family 6 39 1.2E-7 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 VMUT_1018 28a9ea8ae11ac4668d047efddab4a06a 106 Gene3D G3DSA:1.10.1220.10 4 80 3.0E-5 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 VMUT_1018 28a9ea8ae11ac4668d047efddab4a06a 106 SUPERFAMILY SSF47598 5 40 7.51E-5 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 VMUT_2081 2efea161d5104d4878199d81937bd513 505 Gene3D G3DSA:3.80.30.20 189 413 1.1E-17 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe VMUT_2081 2efea161d5104d4878199d81937bd513 505 SUPERFAMILY SSF102114 188 414 8.24E-32 T 23-10-2018 VMUT_2081 2efea161d5104d4878199d81937bd513 505 SMART SM00729 190 402 4.1E-30 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VMUT_2081 2efea161d5104d4878199d81937bd513 505 Pfam PF04055 Radical SAM superfamily 195 357 2.2E-15 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_0621 0ab98fd9706f4460526953c3b0e03329 508 Gene3D G3DSA:3.30.70.20 454 506 1.9E-5 T 23-10-2018 VMUT_0621 0ab98fd9706f4460526953c3b0e03329 508 SUPERFAMILY SSF54862 450 505 7.33E-12 T 23-10-2018 VMUT_0204 e990b70f1b6eaacda40f6ac308ac986d 309 PIRSF PIRSF000102 1 306 3.0E-96 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 VMUT_0204 e990b70f1b6eaacda40f6ac308ac986d 309 PRINTS PR00086 L-lactate dehydrogenase signature 114 134 1.3E-25 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 VMUT_0204 e990b70f1b6eaacda40f6ac308ac986d 309 PRINTS PR00086 L-lactate dehydrogenase signature 1 23 1.3E-25 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 VMUT_0204 e990b70f1b6eaacda40f6ac308ac986d 309 PRINTS PR00086 L-lactate dehydrogenase signature 168 181 1.3E-25 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 VMUT_0204 e990b70f1b6eaacda40f6ac308ac986d 309 PRINTS PR00086 L-lactate dehydrogenase signature 26 50 1.3E-25 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 VMUT_0204 e990b70f1b6eaacda40f6ac308ac986d 309 PRINTS PR00086 L-lactate dehydrogenase signature 138 156 1.3E-25 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 VMUT_0204 e990b70f1b6eaacda40f6ac308ac986d 309 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 144 302 1.2E-21 T 23-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 VMUT_0204 e990b70f1b6eaacda40f6ac308ac986d 309 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 2 140 4.6E-39 T 23-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 VMUT_0204 e990b70f1b6eaacda40f6ac308ac986d 309 Gene3D G3DSA:3.40.50.720 1 142 3.4E-51 T 23-10-2018 VMUT_0204 e990b70f1b6eaacda40f6ac308ac986d 309 Gene3D G3DSA:3.90.110.10 143 301 2.2E-46 T 23-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 VMUT_0204 e990b70f1b6eaacda40f6ac308ac986d 309 SUPERFAMILY SSF51735 2 140 1.22E-47 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0204 e990b70f1b6eaacda40f6ac308ac986d 309 SUPERFAMILY SSF56327 143 302 2.31E-43 T 23-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 VMUT_0444 06c4d53ffad077e21595b412f91012c1 426 Gene3D G3DSA:3.90.1150.10 7 414 2.0E-162 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VMUT_0444 06c4d53ffad077e21595b412f91012c1 426 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 232 268 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VMUT_0444 06c4d53ffad077e21595b412f91012c1 426 Pfam PF00202 Aminotransferase class-III 29 398 7.9E-67 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VMUT_0444 06c4d53ffad077e21595b412f91012c1 426 Gene3D G3DSA:3.40.640.10 67 315 2.0E-162 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VMUT_0444 06c4d53ffad077e21595b412f91012c1 426 SUPERFAMILY SSF53383 2 420 6.81E-118 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VMUT_0444 06c4d53ffad077e21595b412f91012c1 426 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 3 423 88.718 T 23-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 VMUT_0444 06c4d53ffad077e21595b412f91012c1 426 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 4 421 6.1E-171 T 23-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 VMUT_1989 77274864ab207bb37fd3646d3532165f 102 Gene3D G3DSA:3.40.50.720 2 102 2.1E-26 T 23-10-2018 VMUT_1989 77274864ab207bb37fd3646d3532165f 102 Pfam PF00106 short chain dehydrogenase 3 90 1.1E-18 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_1989 77274864ab207bb37fd3646d3532165f 102 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.7E-8 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_1989 77274864ab207bb37fd3646d3532165f 102 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.7E-8 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_1989 77274864ab207bb37fd3646d3532165f 102 SUPERFAMILY SSF51735 3 96 2.6E-24 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1453 b6c03b4c3b2b7289d9fa94b363e7fe1c 412 Pfam PF00149 Calcineurin-like phosphoesterase 2 197 1.3E-11 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 VMUT_1453 b6c03b4c3b2b7289d9fa94b363e7fe1c 412 Gene3D G3DSA:3.60.21.10 1 260 2.3E-44 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like VMUT_1453 b6c03b4c3b2b7289d9fa94b363e7fe1c 412 SUPERFAMILY SSF56300 1 282 2.53E-45 T 23-10-2018 VMUT_1053 c80999a45e11a80a9eccbdb2db7114fa 278 Pfam PF05050 Methyltransferase FkbM domain 113 259 9.4E-6 T 23-10-2018 IPR006342 Methyltransferase FkbM VMUT_1053 c80999a45e11a80a9eccbdb2db7114fa 278 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 110 243 4.8E-14 T 23-10-2018 IPR006342 Methyltransferase FkbM VMUT_1053 c80999a45e11a80a9eccbdb2db7114fa 278 Gene3D G3DSA:3.40.50.150 96 265 2.7E-18 T 23-10-2018 VMUT_1053 c80999a45e11a80a9eccbdb2db7114fa 278 SUPERFAMILY SSF53335 79 243 7.56E-22 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_0105 d3591346a7aea3c65250fa33ef712dfa 213 Pfam PF09840 Uncharacterized protein conserved in archaea (DUF2067) 7 199 6.4E-44 T 23-10-2018 IPR019202 Protein of unknown function DUF2067 VMUT_1834 e91d4ead637ce2b6bf0febeadc9559d1 99 Pfam PF14947 Winged helix-turn-helix 7 75 1.9E-7 T 23-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain VMUT_1834 e91d4ead637ce2b6bf0febeadc9559d1 99 Gene3D G3DSA:1.10.10.10 4 97 4.4E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_1834 e91d4ead637ce2b6bf0febeadc9559d1 99 SUPERFAMILY SSF46785 15 78 5.54E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0249 4d873807dceb586ea9a24fee6927da6a 268 SUPERFAMILY SSF55469 72 265 1.99E-24 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 VMUT_0249 4d873807dceb586ea9a24fee6927da6a 268 Gene3D G3DSA:3.40.109.10 35 263 3.5E-59 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 VMUT_0249 4d873807dceb586ea9a24fee6927da6a 268 Pfam PF00881 Nitroreductase family 79 263 5.2E-21 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 VMUT_0249 4d873807dceb586ea9a24fee6927da6a 268 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 94 263 4.0E-42 T 23-10-2018 IPR020051 SagB-type dehydrogenase domain VMUT_0119 4136d1adba4a3d8a6e59e256eb7185be 341 Gene3D G3DSA:3.40.640.10 32 217 4.7E-25 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VMUT_0119 4136d1adba4a3d8a6e59e256eb7185be 341 SUPERFAMILY SSF53383 40 336 6.36E-38 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VMUT_0119 4136d1adba4a3d8a6e59e256eb7185be 341 Pfam PF00155 Aminotransferase class I and II 41 321 1.0E-12 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VMUT_0119 4136d1adba4a3d8a6e59e256eb7185be 341 Gene3D G3DSA:3.90.1150.10 218 332 8.2E-9 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VMUT_1182 9f4447fa714b69d5a9d2693ea54c141a 195 Pfam PF06195 Protein of unknown function (DUF996) 27 177 5.6E-29 T 23-10-2018 IPR010397 Protein of unknown function DUF996 VMUT_0799 4105316005d15da62675f7e61052a8a2 508 Pfam PF16199 Radical_SAM C-terminal domain 245 325 1.2E-21 T 23-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 VMUT_0799 4105316005d15da62675f7e61052a8a2 508 PIRSF PIRSF005669 2 486 6.6E-191 T 23-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 VMUT_0799 4105316005d15da62675f7e61052a8a2 508 SUPERFAMILY SSF55729 367 481 7.02E-6 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase VMUT_0799 4105316005d15da62675f7e61052a8a2 508 SMART SM00729 23 284 9.2E-40 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VMUT_0799 4105316005d15da62675f7e61052a8a2 508 TIGRFAM TIGR01211 ELP3: radical SAM enzyme/protein acetyltransferase, ELP3 family 11 483 4.3E-177 T 23-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 VMUT_0799 4105316005d15da62675f7e61052a8a2 508 Gene3D G3DSA:3.80.30.20 23 283 6.8E-15 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe VMUT_0799 4105316005d15da62675f7e61052a8a2 508 Pfam PF04055 Radical SAM superfamily 32 228 4.5E-23 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_0799 4105316005d15da62675f7e61052a8a2 508 Gene3D G3DSA:3.40.630.30 428 502 6.5E-6 T 23-10-2018 VMUT_0799 4105316005d15da62675f7e61052a8a2 508 SUPERFAMILY SSF102114 28 290 5.36E-39 T 23-10-2018 VMUT_2304 1154107697456ecafba319067670a304 215 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 5 210 2.2E-65 T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 VMUT_2304 1154107697456ecafba319067670a304 215 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 6 213 35.421 T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 VMUT_2304 1154107697456ecafba319067670a304 215 Gene3D G3DSA:3.40.50.150 2 215 1.8E-75 T 23-10-2018 VMUT_2304 1154107697456ecafba319067670a304 215 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 9 210 6.4E-66 T 23-10-2018 VMUT_2304 1154107697456ecafba319067670a304 215 SUPERFAMILY SSF53335 1 180 3.8E-47 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_0772 7bebb6898930c831f95409d0dbaec3d8 293 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 223 9.5E-40 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 VMUT_0772 7bebb6898930c831f95409d0dbaec3d8 293 SUPERFAMILY SSF51735 1 292 1.67E-76 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0772 7bebb6898930c831f95409d0dbaec3d8 293 Gene3D G3DSA:3.40.50.720 1 293 1.1E-69 T 23-10-2018 VMUT_1554 d04a0439ef91c8a17905530a06c6f969 110 Gene3D G3DSA:1.20.1250.20 3 103 1.0E-9 T 23-10-2018 VMUT_1554 d04a0439ef91c8a17905530a06c6f969 110 SUPERFAMILY SSF103473 15 102 4.45E-9 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_1554 d04a0439ef91c8a17905530a06c6f969 110 Pfam PF00083 Sugar (and other) transporter 30 98 3.4E-7 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VMUT_0691 9e8819f78c58672cf28dcab2862e5946 257 Gene3D G3DSA:2.40.10.330 91 134 9.2E-46 T 23-10-2018 VMUT_0691 9e8819f78c58672cf28dcab2862e5946 257 SUPERFAMILY SSF54534 4 150 1.85E-32 T 23-10-2018 VMUT_0691 9e8819f78c58672cf28dcab2862e5946 257 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 4 88 1.8E-6 T 23-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain VMUT_0691 9e8819f78c58672cf28dcab2862e5946 257 Gene3D G3DSA:3.30.70.2210 153 240 3.2E-11 T 23-10-2018 VMUT_0691 9e8819f78c58672cf28dcab2862e5946 257 Gene3D G3DSA:3.10.50.40 5 148 9.2E-46 T 23-10-2018 VMUT_0122 f7f5fe36f7a8cd62825849a392560a70 329 Pfam PF01895 PhoU domain 135 212 3.2E-11 T 23-10-2018 IPR026022 PhoU domain VMUT_0122 f7f5fe36f7a8cd62825849a392560a70 329 SUPERFAMILY SSF89447 13 52 1.13E-5 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily VMUT_0122 f7f5fe36f7a8cd62825849a392560a70 329 SUPERFAMILY SSF109755 130 271 3.27E-14 T 23-10-2018 VMUT_0122 f7f5fe36f7a8cd62825849a392560a70 329 Gene3D G3DSA:1.20.58.220 121 233 1.5E-8 T 23-10-2018 IPR038078 PhoU-like domain superfamily VMUT_0122 f7f5fe36f7a8cd62825849a392560a70 329 SMART SM00966 10 55 0.0077 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VMUT_0149 20d8a26f108cbea6e4d7e887e30b5518 343 SUPERFAMILY SSF55347 177 282 3.27E-24 T 23-10-2018 VMUT_0149 20d8a26f108cbea6e4d7e887e30b5518 343 Gene3D G3DSA:3.40.50.720 1 336 6.9E-92 T 23-10-2018 VMUT_0149 20d8a26f108cbea6e4d7e887e30b5518 343 Pfam PF01658 Myo-inositol-1-phosphate synthase 179 282 2.9E-21 T 23-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 VMUT_0149 20d8a26f108cbea6e4d7e887e30b5518 343 SUPERFAMILY SSF51735 1 339 4.2E-63 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0149 20d8a26f108cbea6e4d7e887e30b5518 343 PIRSF PIRSF015578 1 339 2.2E-72 T 23-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 VMUT_0149 20d8a26f108cbea6e4d7e887e30b5518 343 Gene3D G3DSA:3.30.360.10 178 283 6.9E-92 T 23-10-2018 VMUT_1460 2d812c659b954a180a8860ee4784ed02 184 Pfam PF05942 Archaeal PaREP1/PaREP8 family 21 142 1.2E-28 T 23-10-2018 IPR010268 Archaeal PaREP1 VMUT_1665 7a56693c19a757f2b8421616f9b6c22c 351 Gene3D G3DSA:1.20.58.220 145 247 1.6E-18 T 23-10-2018 IPR038078 PhoU-like domain superfamily VMUT_1665 7a56693c19a757f2b8421616f9b6c22c 351 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 16 57 5.2E-10 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VMUT_1665 7a56693c19a757f2b8421616f9b6c22c 351 SMART SM00966 15 61 8.1E-9 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VMUT_1665 7a56693c19a757f2b8421616f9b6c22c 351 Pfam PF01895 PhoU domain 149 239 1.8E-16 T 23-10-2018 IPR026022 PhoU domain VMUT_1665 7a56693c19a757f2b8421616f9b6c22c 351 SUPERFAMILY SSF109755 133 345 2.75E-24 T 23-10-2018 VMUT_2185 846a63d2ad1297deba1e2e88971fe3ce 452 Pfam PF01523 Putative modulator of DNA gyrase 23 306 1.5E-28 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 VMUT_2185 846a63d2ad1297deba1e2e88971fe3ce 452 SUPERFAMILY SSF111283 7 445 1.7E-60 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 VMUT_0961 4e3fa9ab8a0313406a20d5bd8be4c852 81 SUPERFAMILY SSF50182 7 78 2.09E-17 T 23-10-2018 IPR010920 LSM domain superfamily VMUT_0961 4e3fa9ab8a0313406a20d5bd8be4c852 81 Gene3D G3DSA:2.30.30.100 1 80 1.3E-20 T 23-10-2018 VMUT_0961 4e3fa9ab8a0313406a20d5bd8be4c852 81 SMART SM00651 9 76 9.0E-15 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type VMUT_0961 4e3fa9ab8a0313406a20d5bd8be4c852 81 Pfam PF01423 LSM domain 10 75 6.9E-18 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type VMUT_2268 1215fa49561237474f0949a1bc2b552d 266 Pfam PF01828 Peptidase A4 family 51 213 2.9E-33 T 23-10-2018 IPR000250 Peptidase G1 GO:0004190|GO:0006508 VMUT_2268 1215fa49561237474f0949a1bc2b552d 266 Gene3D G3DSA:2.60.120.700 79 262 1.9E-38 T 23-10-2018 IPR038656 Peptidase G1 superfamily VMUT_2268 1215fa49561237474f0949a1bc2b552d 266 SUPERFAMILY SSF49899 48 260 1.58E-45 T 23-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily VMUT_0147 1f24326ac9cd0a8d24f830101f6b2f8b 199 SUPERFAMILY SSF52540 1 197 4.3E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0147 1f24326ac9cd0a8d24f830101f6b2f8b 199 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 187 5.8E-46 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 VMUT_0147 1f24326ac9cd0a8d24f830101f6b2f8b 199 ProSitePatterns PS01331 Thymidylate kinase signature. 90 102 - T 23-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 VMUT_0147 1f24326ac9cd0a8d24f830101f6b2f8b 199 Hamap MF_00165 Thymidylate kinase [tmk]. 1 195 24.394 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 VMUT_0147 1f24326ac9cd0a8d24f830101f6b2f8b 199 Pfam PF02223 Thymidylate kinase 5 187 1.1E-45 T 23-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 VMUT_0147 1f24326ac9cd0a8d24f830101f6b2f8b 199 Gene3D G3DSA:3.40.50.300 1 197 8.9E-60 T 23-10-2018 VMUT_1048 65f339db26812385ed2db59f8822bc4b 161 Pfam PF00535 Glycosyl transferase family 2 12 108 1.0E-12 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VMUT_1048 65f339db26812385ed2db59f8822bc4b 161 SUPERFAMILY SSF53448 5 152 2.67E-17 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1048 65f339db26812385ed2db59f8822bc4b 161 Gene3D G3DSA:3.90.550.10 1 160 1.4E-19 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0488 5ca5272370544e0e52d05a254920ce0b 219 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 6 186 3.1E-37 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 VMUT_0488 5ca5272370544e0e52d05a254920ce0b 219 Gene3D G3DSA:3.40.1010.10 4 116 3.8E-33 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 VMUT_0488 5ca5272370544e0e52d05a254920ce0b 219 SUPERFAMILY SSF53790 6 208 2.62E-45 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 VMUT_1650 ba93fd32f1b6485b97fd3047b1bba121 545 SMART SM00729 229 463 4.0E-17 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VMUT_1650 ba93fd32f1b6485b97fd3047b1bba121 545 Pfam PF04055 Radical SAM superfamily 233 419 9.9E-17 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_1650 ba93fd32f1b6485b97fd3047b1bba121 545 SUPERFAMILY SSF102114 230 467 2.22E-21 T 23-10-2018 VMUT_1650 ba93fd32f1b6485b97fd3047b1bba121 545 Gene3D G3DSA:3.80.30.20 229 446 5.0E-22 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe VMUT_0209 eeb62e5bdc5def5bc00a503c3405d996 326 SUPERFAMILY SSF51735 2 326 2.66E-88 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0209 eeb62e5bdc5def5bc00a503c3405d996 326 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 21 318 1.9E-72 T 23-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 VMUT_0209 eeb62e5bdc5def5bc00a503c3405d996 326 PIRSF PIRSF001439 1 326 1.0E-78 T 23-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 VMUT_0209 eeb62e5bdc5def5bc00a503c3405d996 326 Gene3D G3DSA:3.40.50.720 127 299 2.3E-92 T 23-10-2018 VMUT_0209 eeb62e5bdc5def5bc00a503c3405d996 326 Gene3D G3DSA:3.30.1780.10 9 321 2.3E-92 T 23-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 VMUT_1389 dbc147c73608fc64a98d40ca8b5eb710 97 Gene3D G3DSA:3.40.50.300 2 97 2.2E-5 T 23-10-2018 VMUT_0895 552629d78f311565b41498de975d6fdf 258 Pfam PF09958 Uncharacterized protein conserved in archaea (DUF2192) 8 245 6.7E-76 T 23-10-2018 IPR018693 Protein of unknown function DUF2192 VMUT_1324 cdaeb634dc9c6e8f0bb493e8b5033067 282 Gene3D G3DSA:1.10.260.40 128 217 6.6E-12 T 23-10-2018 VMUT_1324 cdaeb634dc9c6e8f0bb493e8b5033067 282 SMART SM00530 134 189 6.5E-10 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VMUT_1324 cdaeb634dc9c6e8f0bb493e8b5033067 282 Hamap MF_00584 Putative HTH-type transcriptional regulatory protein . 1 274 14.79 T 23-10-2018 IPR020886 Transcription regulator HTH, Cro/C1-type DNA-binding GO:0003700|GO:0006355 VMUT_1324 cdaeb634dc9c6e8f0bb493e8b5033067 282 Pfam PF01381 Helix-turn-helix 135 185 1.3E-11 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VMUT_1324 cdaeb634dc9c6e8f0bb493e8b5033067 282 SUPERFAMILY SSF47413 132 186 3.75E-12 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VMUT_1062 3f21b22bb5045d5610a987f8953bc6c3 335 Pfam PF00534 Glycosyl transferases group 1 138 308 5.4E-18 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 VMUT_1062 3f21b22bb5045d5610a987f8953bc6c3 335 SUPERFAMILY SSF53756 116 332 2.41E-33 T 23-10-2018 VMUT_1062 3f21b22bb5045d5610a987f8953bc6c3 335 Gene3D G3DSA:3.40.50.2000 150 320 1.8E-22 T 23-10-2018 VMUT_2104 8326e15b842f13b3de965976f45d4890 419 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 279 330 3.0E-14 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_2104 8326e15b842f13b3de965976f45d4890 419 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 226 345 1.2E-25 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_2104 8326e15b842f13b3de965976f45d4890 419 Gene3D G3DSA:3.40.50.12280 2 158 2.0E-52 T 23-10-2018 VMUT_2104 8326e15b842f13b3de965976f45d4890 419 Gene3D G3DSA:3.30.460.80 186 324 1.9E-23 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_2104 8326e15b842f13b3de965976f45d4890 419 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 36 134 6.2E-20 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_2104 8326e15b842f13b3de965976f45d4890 419 SUPERFAMILY SSF56770 6 144 2.49E-53 T 23-10-2018 VMUT_2104 8326e15b842f13b3de965976f45d4890 419 SUPERFAMILY SSF143243 206 351 1.7E-32 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_2104 8326e15b842f13b3de965976f45d4890 419 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 141 1.8E-46 T 23-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_1167 24dcbb4d3c61a50b4ac3c620f2ddec8f 489 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 23-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 VMUT_1167 24dcbb4d3c61a50b4ac3c620f2ddec8f 489 Gene3D G3DSA:3.40.605.10 22 461 7.4E-170 T 23-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VMUT_1167 24dcbb4d3c61a50b4ac3c620f2ddec8f 489 SUPERFAMILY SSF53720 4 472 5.24E-151 T 23-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VMUT_1167 24dcbb4d3c61a50b4ac3c620f2ddec8f 489 Gene3D G3DSA:3.40.309.10 253 441 7.4E-170 T 23-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VMUT_1167 24dcbb4d3c61a50b4ac3c620f2ddec8f 489 Pfam PF00171 Aldehyde dehydrogenase family 16 466 1.5E-156 T 23-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VMUT_2261 d2ddbd96b27d8bc4d1ef4beefeb075a9 388 SUPERFAMILY SSF103473 5 386 1.57E-30 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_2261 d2ddbd96b27d8bc4d1ef4beefeb075a9 388 Pfam PF07690 Major Facilitator Superfamily 215 378 3.1E-10 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_2261 d2ddbd96b27d8bc4d1ef4beefeb075a9 388 Gene3D G3DSA:1.20.1250.20 2 186 4.7E-9 T 23-10-2018 VMUT_2261 d2ddbd96b27d8bc4d1ef4beefeb075a9 388 Gene3D G3DSA:1.20.1250.20 210 388 7.3E-14 T 23-10-2018 VMUT_1998 e63d7c7a8c11ebbc0fb24184cda42b2d 245 Gene3D G3DSA:3.40.50.10420 39 210 1.0E-8 T 23-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily VMUT_1998 e63d7c7a8c11ebbc0fb24184cda42b2d 245 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 7 202 2.9E-30 T 23-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase VMUT_1998 e63d7c7a8c11ebbc0fb24184cda42b2d 245 SUPERFAMILY SSF100950 6 221 5.72E-31 T 23-10-2018 IPR037171 NagB/RpiA transferase-like VMUT_0715 5378d6bbf3d27c831e0a2c677eee317c 367 Pfam PF13378 Enolase C-terminal domain-like 148 363 3.4E-64 T 23-10-2018 IPR029065 Enolase C-terminal domain-like VMUT_0715 5378d6bbf3d27c831e0a2c677eee317c 367 SMART SM00922 145 244 1.7E-27 T 23-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal VMUT_0715 5378d6bbf3d27c831e0a2c677eee317c 367 Gene3D G3DSA:3.20.20.120 125 361 2.5E-79 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VMUT_0715 5378d6bbf3d27c831e0a2c677eee317c 367 SUPERFAMILY SSF51604 115 364 4.06E-75 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VMUT_0715 5378d6bbf3d27c831e0a2c677eee317c 367 SUPERFAMILY SSF54826 2 129 3.54E-28 T 23-10-2018 VMUT_0715 5378d6bbf3d27c831e0a2c677eee317c 367 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 24 127 3.9E-13 T 23-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain VMUT_0715 5378d6bbf3d27c831e0a2c677eee317c 367 Gene3D G3DSA:3.30.390.10 1 124 5.6E-28 T 23-10-2018 IPR029017 Enolase-like, N-terminal VMUT_0245 fd03a0840f4e0a06299c6878426e951c 371 Pfam PF16575 mRNA cleavage and polyadenylation factor CLP1 P-loop 89 258 3.7E-32 T 23-10-2018 IPR032319 Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain VMUT_0245 fd03a0840f4e0a06299c6878426e951c 371 Gene3D G3DSA:3.40.50.300 80 264 1.8E-27 T 23-10-2018 VMUT_0245 fd03a0840f4e0a06299c6878426e951c 371 SUPERFAMILY SSF52540 86 211 1.76E-8 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0370 7ce5612337a4289b0bc13ef1d85f785a 218 Gene3D G3DSA:3.30.470.50 9 154 9.7E-73 T 23-10-2018 VMUT_0972 cb4d8ca8bb06a93892aebbd71bad8166 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 258 1.8E-52 T 23-10-2018 VMUT_0972 cb4d8ca8bb06a93892aebbd71bad8166 263 Gene3D G3DSA:3.40.50.720 1 259 4.7E-68 T 23-10-2018 VMUT_0972 cb4d8ca8bb06a93892aebbd71bad8166 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 5.1E-30 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0972 cb4d8ca8bb06a93892aebbd71bad8166 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 5.1E-30 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0972 cb4d8ca8bb06a93892aebbd71bad8166 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 5.1E-30 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0972 cb4d8ca8bb06a93892aebbd71bad8166 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.1E-30 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0972 cb4d8ca8bb06a93892aebbd71bad8166 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 5.1E-30 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0972 cb4d8ca8bb06a93892aebbd71bad8166 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 5.1E-30 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0972 cb4d8ca8bb06a93892aebbd71bad8166 263 SUPERFAMILY SSF51735 7 259 1.85E-71 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0271 c16c57e3b5f93fba9537ab735064eb66 255 Gene3D G3DSA:3.40.50.1000 13 118 9.2E-9 T 23-10-2018 IPR023214 HAD superfamily VMUT_0271 c16c57e3b5f93fba9537ab735064eb66 255 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 15 216 7.2E-14 T 23-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 VMUT_0271 c16c57e3b5f93fba9537ab735064eb66 255 Gene3D G3DSA:3.40.50.1000 136 224 6.8E-7 T 23-10-2018 IPR023214 HAD superfamily VMUT_0271 c16c57e3b5f93fba9537ab735064eb66 255 SUPERFAMILY SSF56784 15 220 4.31E-23 T 23-10-2018 IPR036412 HAD-like superfamily VMUT_0271 c16c57e3b5f93fba9537ab735064eb66 255 Pfam PF02358 Trehalose-phosphatase 17 205 3.6E-10 T 23-10-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 VMUT_1444 f491f8be5e6afc84e45aaab0b8412cfb 380 Pfam PF07690 Major Facilitator Superfamily 8 332 8.3E-28 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_1444 f491f8be5e6afc84e45aaab0b8412cfb 380 Gene3D G3DSA:1.20.1250.20 6 183 4.7E-16 T 23-10-2018 VMUT_1444 f491f8be5e6afc84e45aaab0b8412cfb 380 Gene3D G3DSA:1.20.1250.20 187 370 9.5E-17 T 23-10-2018 VMUT_1444 f491f8be5e6afc84e45aaab0b8412cfb 380 SUPERFAMILY SSF103473 11 372 1.18E-39 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_0333 605bebb4ef62e7d5c747b665a81cd99d 263 Gene3D G3DSA:3.40.50.720 5 259 5.7E-76 T 23-10-2018 VMUT_0333 605bebb4ef62e7d5c747b665a81cd99d 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 94 105 1.4E-8 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0333 605bebb4ef62e7d5c747b665a81cd99d 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 157 1.4E-8 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0333 605bebb4ef62e7d5c747b665a81cd99d 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 169 188 1.4E-8 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0333 605bebb4ef62e7d5c747b665a81cd99d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 3.2E-38 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0333 605bebb4ef62e7d5c747b665a81cd99d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 3.2E-38 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0333 605bebb4ef62e7d5c747b665a81cd99d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 188 3.2E-38 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0333 605bebb4ef62e7d5c747b665a81cd99d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 3.2E-38 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0333 605bebb4ef62e7d5c747b665a81cd99d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 3.2E-38 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0333 605bebb4ef62e7d5c747b665a81cd99d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 3.2E-38 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_0333 605bebb4ef62e7d5c747b665a81cd99d 263 SUPERFAMILY SSF51735 17 258 7.15E-79 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0333 605bebb4ef62e7d5c747b665a81cd99d 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 257 7.2E-65 T 23-10-2018 VMUT_0177 1957a29f61e56b069797a98e921042e0 406 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 24 397 3.1E-122 T 23-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase VMUT_0177 1957a29f61e56b069797a98e921042e0 406 Gene3D G3DSA:3.90.1150.10 256 402 3.2E-26 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VMUT_0177 1957a29f61e56b069797a98e921042e0 406 SUPERFAMILY SSF53383 17 401 1.53E-113 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VMUT_0177 1957a29f61e56b069797a98e921042e0 406 PIRSF PIRSF000390 17 404 3.1E-113 T 23-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase VMUT_0177 1957a29f61e56b069797a98e921042e0 406 Gene3D G3DSA:3.40.640.10 12 255 5.6E-98 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VMUT_0361 7dbbe3243f07eff44e1a162a90bee038 269 SUPERFAMILY SSF56281 28 249 5.63E-24 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_0361 7dbbe3243f07eff44e1a162a90bee038 269 Pfam PF00753 Metallo-beta-lactamase superfamily 33 85 1.7E-10 T 23-10-2018 IPR001279 Metallo-beta-lactamase VMUT_0361 7dbbe3243f07eff44e1a162a90bee038 269 Gene3D G3DSA:3.60.15.10 1 268 9.4E-63 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_1117 f0c1db344127c48f3538ca96eb2db77a 148 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 13 138 7.0E-39 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 VMUT_1117 f0c1db344127c48f3538ca96eb2db77a 148 Gene3D G3DSA:3.55.10.10 7 148 2.0E-38 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 VMUT_1117 f0c1db344127c48f3538ca96eb2db77a 148 Pfam PF01951 Archease protein family (MTH1598/TM1083) 9 148 8.4E-40 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 VMUT_1117 f0c1db344127c48f3538ca96eb2db77a 148 SUPERFAMILY SSF69819 7 148 7.06E-39 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 VMUT_1117 f0c1db344127c48f3538ca96eb2db77a 148 Hamap MF_01222 Protein archease. 7 148 36.241 T 23-10-2018 IPR022952 Archease, archaea VMUT_2296 07fe77a09d07fc73f4f2a8a9a48c116e 203 Pfam PF00857 Isochorismatase family 26 187 5.4E-41 T 23-10-2018 IPR000868 Isochorismatase-like GO:0003824 VMUT_2296 07fe77a09d07fc73f4f2a8a9a48c116e 203 SUPERFAMILY SSF52499 18 200 1.96E-59 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VMUT_2296 07fe77a09d07fc73f4f2a8a9a48c116e 203 Gene3D G3DSA:3.40.50.850 6 200 1.6E-57 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VMUT_2339 f6c339bcf68872d0a72520ca5a0c5b6a 371 SUPERFAMILY SSF46548 17 95 1.19E-16 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VMUT_2339 f6c339bcf68872d0a72520ca5a0c5b6a 371 SUPERFAMILY SSF103501 209 357 1.57E-14 T 23-10-2018 IPR036197 NarG-like superfamily VMUT_2339 f6c339bcf68872d0a72520ca5a0c5b6a 371 Gene3D G3DSA:1.10.1060.10 1 98 1.9E-6 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VMUT_2339 f6c339bcf68872d0a72520ca5a0c5b6a 371 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 67 78 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_2339 f6c339bcf68872d0a72520ca5a0c5b6a 371 Pfam PF13183 4Fe-4S dicluster domain 20 80 1.1E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_0739 f67871d2d4206b1e96b945232ff402f3 134 SUPERFAMILY SSF46785 6 84 7.49E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0739 f67871d2d4206b1e96b945232ff402f3 134 SMART SM00529 25 122 4.2E-14 T 23-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 VMUT_0739 f67871d2d4206b1e96b945232ff402f3 134 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 63 130 2.4E-20 T 23-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 VMUT_0739 f67871d2d4206b1e96b945232ff402f3 134 Gene3D G3DSA:1.10.10.10 1 130 1.4E-37 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_0739 f67871d2d4206b1e96b945232ff402f3 134 SUPERFAMILY SSF47979 63 132 2.22E-18 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 VMUT_1436 79e872b4b68c0c7c0c92b0595ced80e9 187 Pfam PF00156 Phosphoribosyl transferase domain 17 149 3.9E-26 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 VMUT_1436 79e872b4b68c0c7c0c92b0595ced80e9 187 SUPERFAMILY SSF53271 4 155 6.69E-35 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like VMUT_1436 79e872b4b68c0c7c0c92b0595ced80e9 187 Gene3D G3DSA:3.40.50.2020 1 168 1.8E-44 T 23-10-2018 VMUT_2073 42b3d7202a6cbb1a55883f1490762634 133 Pfam PF06677 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) 11 49 3.2E-13 T 23-10-2018 IPR009563 Sjoegren syndrome/scleroderma autoantigen 1 VMUT_0590 68cb812db74e66757d6d7c51ca71fd21 327 Gene3D G3DSA:3.30.420.40 4 307 3.4E-80 T 23-10-2018 VMUT_0590 68cb812db74e66757d6d7c51ca71fd21 327 SUPERFAMILY SSF53067 1 310 6.24E-58 T 23-10-2018 VMUT_0590 68cb812db74e66757d6d7c51ca71fd21 327 Pfam PF00480 ROK family 3 310 5.6E-60 T 23-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 VMUT_0590 68cb812db74e66757d6d7c51ca71fd21 327 Gene3D G3DSA:3.30.420.40 122 294 3.4E-80 T 23-10-2018 VMUT_0369 6e17ea74a1671ee049fcddf7c0e0a47c 246 Gene3D G3DSA:3.40.50.2020 64 245 7.7E-31 T 23-10-2018 VMUT_0369 6e17ea74a1671ee049fcddf7c0e0a47c 246 SUPERFAMILY SSF53271 79 243 1.84E-28 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like VMUT_0369 6e17ea74a1671ee049fcddf7c0e0a47c 246 Pfam PF00156 Phosphoribosyl transferase domain 96 227 4.7E-10 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 VMUT_1818 477da8cf873f283be8a8050c29a0b563 412 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 26 311 7.6E-89 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme VMUT_1818 477da8cf873f283be8a8050c29a0b563 412 Gene3D G3DSA:3.40.50.1100 24 316 9.4E-120 T 23-10-2018 VMUT_1818 477da8cf873f283be8a8050c29a0b563 412 Pfam PF01842 ACT domain 340 394 8.0E-8 T 23-10-2018 IPR002912 ACT domain VMUT_1818 477da8cf873f283be8a8050c29a0b563 412 Gene3D G3DSA:3.30.70.260 333 411 2.9E-8 T 23-10-2018 VMUT_1818 477da8cf873f283be8a8050c29a0b563 412 SUPERFAMILY SSF53686 11 360 1.23E-101 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme VMUT_1818 477da8cf873f283be8a8050c29a0b563 412 SUPERFAMILY SSF55021 339 409 9.99E-8 T 23-10-2018 VMUT_1818 477da8cf873f283be8a8050c29a0b563 412 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 30 409 2.3E-144 T 23-10-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 VMUT_1818 477da8cf873f283be8a8050c29a0b563 412 Gene3D G3DSA:3.40.50.1100 59 155 9.4E-120 T 23-10-2018 VMUT_0017 c345ec9cd91491119c4b575121ce561a 259 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 97 117 - T 23-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 VMUT_0017 c345ec9cd91491119c4b575121ce561a 259 SUPERFAMILY SSF52096 4 247 9.96E-70 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VMUT_0017 c345ec9cd91491119c4b575121ce561a 259 Gene3D G3DSA:3.90.226.10 7 225 7.7E-67 T 23-10-2018 VMUT_0017 c345ec9cd91491119c4b575121ce561a 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 247 2.4E-43 T 23-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VMUT_1450 a76125488ba7234f2f35068c518b3a96 297 SUPERFAMILY SSF46785 9 80 1.45E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_1450 a76125488ba7234f2f35068c518b3a96 297 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 6 81 2.5E-26 T 23-10-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 VMUT_1450 a76125488ba7234f2f35068c518b3a96 297 Pfam PF00571 CBS domain 177 231 6.3E-13 T 23-10-2018 IPR000644 CBS domain VMUT_1450 a76125488ba7234f2f35068c518b3a96 297 Pfam PF00571 CBS domain 240 294 1.7E-13 T 23-10-2018 IPR000644 CBS domain VMUT_1450 a76125488ba7234f2f35068c518b3a96 297 SMART SM00116 184 232 3.6E-9 T 23-10-2018 IPR000644 CBS domain VMUT_1450 a76125488ba7234f2f35068c518b3a96 297 SMART SM00116 247 294 5.4E-12 T 23-10-2018 IPR000644 CBS domain VMUT_1450 a76125488ba7234f2f35068c518b3a96 297 SUPERFAMILY SSF54631 172 294 3.26E-34 T 23-10-2018 VMUT_1450 a76125488ba7234f2f35068c518b3a96 297 PIRSF PIRSF005063 3 297 8.1E-94 T 23-10-2018 IPR016436 Uncharacterised conserved protein UCP005063, CBS-type VMUT_1450 a76125488ba7234f2f35068c518b3a96 297 Gene3D G3DSA:1.10.10.10 1 83 8.6E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_1450 a76125488ba7234f2f35068c518b3a96 297 Gene3D G3DSA:3.10.580.10 170 297 5.8E-36 T 23-10-2018 VMUT_2305 9cdd1bf9d03d8a805addea6f3cae9643 126 Pfam PF05610 Protein of unknown function (DUF779) 15 106 5.2E-21 T 23-10-2018 IPR008497 Protein of unknown function DUF779 VMUT_1224 53be16a3fbc1720f0b8c9c1b5f9141e0 164 Gene3D G3DSA:3.10.690.10 9 152 1.0E-32 T 23-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 VMUT_1224 53be16a3fbc1720f0b8c9c1b5f9141e0 164 SUPERFAMILY SSF103256 14 148 1.02E-31 T 23-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 VMUT_1224 53be16a3fbc1720f0b8c9c1b5f9141e0 164 Pfam PF02577 Bifunctional nuclease 29 141 8.8E-30 T 23-10-2018 IPR003729 Bifunctional nuclease domain GO:0004518 VMUT_1791 8868834ce9184cf0f193218f41b33fd2 284 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 2 282 15.311 T 23-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 VMUT_1791 8868834ce9184cf0f193218f41b33fd2 284 Pfam PF01040 UbiA prenyltransferase family 19 263 1.1E-42 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 VMUT_1791 8868834ce9184cf0f193218f41b33fd2 284 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 4 278 1.7E-67 T 23-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 VMUT_1791 8868834ce9184cf0f193218f41b33fd2 284 Gene3D G3DSA:1.10.357.140 10 168 1.1E-13 T 23-10-2018 VMUT_1791 8868834ce9184cf0f193218f41b33fd2 284 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 57 79 - T 23-10-2018 IPR030470 UbiA prenyltransferase conserved site VMUT_1893 fb209f819f7e2c28181bc2d111acd680 134 SUPERFAMILY SSF143422 2 127 1.7E-43 T 23-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 VMUT_1893 fb209f819f7e2c28181bc2d111acd680 134 SMART SM01321 11 127 1.9E-41 T 23-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 VMUT_1893 fb209f819f7e2c28181bc2d111acd680 134 Gene3D G3DSA:3.30.70.1290 1 134 2.0E-42 T 23-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 VMUT_1893 fb209f819f7e2c28181bc2d111acd680 134 Pfam PF01797 Transposase IS200 like 12 127 2.3E-36 T 23-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 VMUT_1310 b392e765992f4cea9e39018c16874afe 433 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 362 421 9.5E-12 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain VMUT_1310 b392e765992f4cea9e39018c16874afe 433 SMART SM00849 16 202 3.7E-21 T 23-10-2018 IPR001279 Metallo-beta-lactamase VMUT_1310 b392e765992f4cea9e39018c16874afe 433 Pfam PF10996 Beta-Casp domain 246 344 1.4E-13 T 23-10-2018 IPR022712 Beta-Casp domain VMUT_1310 b392e765992f4cea9e39018c16874afe 433 Gene3D G3DSA:3.60.15.10 9 405 5.1E-99 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_1310 b392e765992f4cea9e39018c16874afe 433 Gene3D G3DSA:3.40.50.10890 204 373 5.1E-99 T 23-10-2018 VMUT_1310 b392e765992f4cea9e39018c16874afe 433 Pfam PF00753 Metallo-beta-lactamase superfamily 16 178 4.4E-13 T 23-10-2018 IPR001279 Metallo-beta-lactamase VMUT_1310 b392e765992f4cea9e39018c16874afe 433 SMART SM01027 236 346 9.4E-25 T 23-10-2018 IPR022712 Beta-Casp domain VMUT_1310 b392e765992f4cea9e39018c16874afe 433 SUPERFAMILY SSF56281 5 429 1.76E-95 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_1298 0b2e10b45bd6b2dbbd7716b4e2d9c2d9 289 SUPERFAMILY SSF52540 8 239 2.24E-67 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1298 0b2e10b45bd6b2dbbd7716b4e2d9c2d9 289 SMART SM00382 37 226 8.2E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_1298 0b2e10b45bd6b2dbbd7716b4e2d9c2d9 289 Pfam PF00005 ABC transporter 30 177 4.1E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_1298 0b2e10b45bd6b2dbbd7716b4e2d9c2d9 289 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VMUT_1298 0b2e10b45bd6b2dbbd7716b4e2d9c2d9 289 Gene3D G3DSA:3.40.50.300 5 280 2.8E-63 T 23-10-2018 VMUT_1583 463778a728f27ee3503f22966131fc29 107 SUPERFAMILY SSF49764 23 97 4.19E-12 T 23-10-2018 IPR008978 HSP20-like chaperone VMUT_1583 463778a728f27ee3503f22966131fc29 107 Gene3D G3DSA:2.60.40.790 18 100 1.3E-10 T 23-10-2018 IPR008978 HSP20-like chaperone VMUT_0417 18c763cbe8ffb55fcb5b2eb6bffeadfc 192 Gene3D G3DSA:1.20.5.170 11 68 9.1E-7 T 23-10-2018 VMUT_1265 6b87741ea46e6de8dc3aa54241516983 614 Pfam PF00723 Glycosyl hydrolases family 15 344 553 3.4E-11 T 23-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 VMUT_1265 6b87741ea46e6de8dc3aa54241516983 614 Gene3D G3DSA:1.50.10.10 239 614 4.1E-85 T 23-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 VMUT_1265 6b87741ea46e6de8dc3aa54241516983 614 SUPERFAMILY SSF48208 218 612 1.42E-94 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 VMUT_0980 10195c873985c1d0741a68abe0f82c9f 488 Pfam PF00860 Permease family 27 444 2.6E-25 T 23-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 VMUT_2120 ad90a8fca627403ab7bd68ff9a79d881 498 SUPERFAMILY SSF53300 318 489 9.64E-31 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily VMUT_2120 ad90a8fca627403ab7bd68ff9a79d881 498 SMART SM00327 319 491 5.9E-22 T 23-10-2018 IPR002035 von Willebrand factor, type A VMUT_2120 ad90a8fca627403ab7bd68ff9a79d881 498 Pfam PF00092 von Willebrand factor type A domain 321 485 1.1E-18 T 23-10-2018 IPR002035 von Willebrand factor, type A VMUT_2120 ad90a8fca627403ab7bd68ff9a79d881 498 Gene3D G3DSA:3.40.50.410 312 495 1.2E-31 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily VMUT_0859 2cb2f6305a5eadb2ffe2798e4931620e 204 SUPERFAMILY SSF55729 32 131 3.71E-16 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase VMUT_0859 2cb2f6305a5eadb2ffe2798e4931620e 204 Pfam PF13508 Acetyltransferase (GNAT) domain 52 127 1.7E-8 T 23-10-2018 IPR000182 GNAT domain VMUT_0859 2cb2f6305a5eadb2ffe2798e4931620e 204 Gene3D G3DSA:3.40.630.30 13 132 1.9E-13 T 23-10-2018 VMUT_0291 58738573367ce0ad54fcfd09ae6993c7 76 Gene3D G3DSA:1.10.20.10 1 66 1.8E-19 T 23-10-2018 IPR009072 Histone-fold GO:0046982 VMUT_0291 58738573367ce0ad54fcfd09ae6993c7 76 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 3 65 1.5E-13 T 23-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain VMUT_0291 58738573367ce0ad54fcfd09ae6993c7 76 SUPERFAMILY SSF47113 3 69 2.84E-18 T 23-10-2018 IPR009072 Histone-fold GO:0046982 VMUT_1133 5dc8755cceee320b2b0482229f2c396b 425 Gene3D G3DSA:3.30.9.90 69 369 1.1E-60 T 23-10-2018 VMUT_1133 5dc8755cceee320b2b0482229f2c396b 425 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 337 353 6.2E-8 T 23-10-2018 VMUT_1133 5dc8755cceee320b2b0482229f2c396b 425 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 6.2E-8 T 23-10-2018 VMUT_1133 5dc8755cceee320b2b0482229f2c396b 425 SUPERFAMILY SSF54373 177 277 5.89E-18 T 23-10-2018 VMUT_1133 5dc8755cceee320b2b0482229f2c396b 425 Pfam PF03486 HI0933-like protein 5 157 5.6E-11 T 23-10-2018 VMUT_1133 5dc8755cceee320b2b0482229f2c396b 425 SUPERFAMILY SSF51905 4 416 2.41E-42 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_1133 5dc8755cceee320b2b0482229f2c396b 425 Gene3D G3DSA:3.50.50.60 5 361 1.1E-60 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0783 b6062ab53d7c407de0df8c839abf86e6 332 Gene3D G3DSA:1.20.1420.30 35 321 1.2E-24 T 23-10-2018 VMUT_0783 b6062ab53d7c407de0df8c839abf86e6 332 Gene3D G3DSA:1.20.58.1130 9 222 1.2E-24 T 23-10-2018 VMUT_0783 b6062ab53d7c407de0df8c839abf86e6 332 Pfam PF01699 Sodium/calcium exchanger protein 191 329 1.2E-5 T 23-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 VMUT_0783 b6062ab53d7c407de0df8c839abf86e6 332 Pfam PF01699 Sodium/calcium exchanger protein 5 158 9.6E-13 T 23-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 VMUT_1219 8c88a117a2f27c21756bf430073dd468 184 SUPERFAMILY SSF55608 69 168 5.39E-6 T 23-10-2018 IPR027434 Homing endonuclease VMUT_0506 5de2e29532d1806a4040fff3189d6ee5 172 SUPERFAMILY SSF81301 8 135 4.21E-21 T 23-10-2018 VMUT_0506 5de2e29532d1806a4040fff3189d6ee5 172 Pfam PF01909 Nucleotidyltransferase domain 19 92 3.4E-8 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 VMUT_0506 5de2e29532d1806a4040fff3189d6ee5 172 Gene3D G3DSA:3.30.460.10 6 136 3.2E-28 T 23-10-2018 VMUT_1867 ef439752485659fa97c319f0d59b092e 146 Gene3D G3DSA:3.60.90.10 9 143 1.1E-38 T 23-10-2018 VMUT_1867 ef439752485659fa97c319f0d59b092e 146 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 18 129 8.2E-39 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 VMUT_1867 ef439752485659fa97c319f0d59b092e 146 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 16 133 28.92 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 VMUT_1867 ef439752485659fa97c319f0d59b092e 146 Pfam PF02675 S-adenosylmethionine decarboxylase 22 128 1.9E-34 T 23-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 VMUT_1867 ef439752485659fa97c319f0d59b092e 146 SUPERFAMILY SSF56276 19 130 8.24E-37 T 23-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 VMUT_0894 6325567d50b9dc3513e1974b65981d3f 350 Gene3D G3DSA:3.40.50.150 170 350 8.6E-39 T 23-10-2018 VMUT_0894 6325567d50b9dc3513e1974b65981d3f 350 SUPERFAMILY SSF143437 40 162 5.76E-7 T 23-10-2018 VMUT_0894 6325567d50b9dc3513e1974b65981d3f 350 Gene3D G3DSA:3.30.2130.30 1 167 1.2E-15 T 23-10-2018 VMUT_0894 6325567d50b9dc3513e1974b65981d3f 350 Pfam PF01170 Putative RNA methylase family UPF0020 171 341 5.3E-28 T 23-10-2018 IPR000241 Putative RNA methylase domain VMUT_0894 6325567d50b9dc3513e1974b65981d3f 350 SUPERFAMILY SSF53335 155 307 3.15E-28 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_2336 15ce12a387f2380aa4edc83a22fdf351 267 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 190 1.4E-8 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain VMUT_2336 15ce12a387f2380aa4edc83a22fdf351 267 SUPERFAMILY SSF52540 4 263 6.6E-25 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_2336 15ce12a387f2380aa4edc83a22fdf351 267 Gene3D G3DSA:3.40.50.300 1 253 2.8E-25 T 23-10-2018 VMUT_2139 2ad9d6d983685cdee4bc0078ba0de529 150 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 71 129 9.0E-9 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_2139 2ad9d6d983685cdee4bc0078ba0de529 150 Pfam PF00366 Ribosomal protein S17 70 130 1.2E-19 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_2139 2ad9d6d983685cdee4bc0078ba0de529 150 SUPERFAMILY SSF50249 66 136 8.14E-20 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold VMUT_2139 2ad9d6d983685cdee4bc0078ba0de529 150 PRINTS PR00973 Ribosomal protein S17 family signature 110 120 1.0E-7 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_2139 2ad9d6d983685cdee4bc0078ba0de529 150 PRINTS PR00973 Ribosomal protein S17 family signature 77 100 1.0E-7 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_2139 2ad9d6d983685cdee4bc0078ba0de529 150 PRINTS PR00973 Ribosomal protein S17 family signature 120 127 1.0E-7 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_2139 2ad9d6d983685cdee4bc0078ba0de529 150 TIGRFAM TIGR03630 uS17_arch: ribosomal protein uS17 32 132 1.2E-40 T 23-10-2018 IPR028333 Ribosomal protein S17, archaeal/eukaryotic Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_2139 2ad9d6d983685cdee4bc0078ba0de529 150 Hamap MF_01345_A 30S ribosomal protein S17 [rpsQ]. 30 134 28.23 T 23-10-2018 IPR019978 Ribosomal protein S17, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_2139 2ad9d6d983685cdee4bc0078ba0de529 150 Gene3D G3DSA:2.40.50.1000 18 145 1.9E-29 T 23-10-2018 VMUT_0508 0fab03d486744f0a4660dd8c6a895750 279 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 136 153 - T 23-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 VMUT_0508 0fab03d486744f0a4660dd8c6a895750 279 SUPERFAMILY SSF51430 15 276 1.07E-76 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VMUT_0508 0fab03d486744f0a4660dd8c6a895750 279 Gene3D G3DSA:3.20.20.100 8 275 2.2E-79 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VMUT_0508 0fab03d486744f0a4660dd8c6a895750 279 Pfam PF00248 Aldo/keto reductase family 20 275 2.0E-55 T 23-10-2018 IPR023210 NADP-dependent oxidoreductase domain VMUT_0508 0fab03d486744f0a4660dd8c6a895750 279 PRINTS PR00069 Aldo-keto reductase signature 49 73 3.2E-18 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VMUT_0508 0fab03d486744f0a4660dd8c6a895750 279 PRINTS PR00069 Aldo-keto reductase signature 136 153 3.2E-18 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VMUT_0508 0fab03d486744f0a4660dd8c6a895750 279 PRINTS PR00069 Aldo-keto reductase signature 173 202 3.2E-18 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VMUT_0508 0fab03d486744f0a4660dd8c6a895750 279 PRINTS PR00069 Aldo-keto reductase signature 105 123 3.2E-18 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VMUT_0508 0fab03d486744f0a4660dd8c6a895750 279 PRINTS PR00069 Aldo-keto reductase signature 210 234 3.2E-18 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VMUT_1066 19d94cf06aaea1c911820301d561b851 232 Pfam PF01522 Polysaccharide deacetylase 6 118 1.7E-15 T 23-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 VMUT_1066 19d94cf06aaea1c911820301d561b851 232 Gene3D G3DSA:3.20.20.370 3 157 2.5E-25 T 23-10-2018 VMUT_1066 19d94cf06aaea1c911820301d561b851 232 SUPERFAMILY SSF88713 6 193 2.72E-27 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 VMUT_2078 a91abfed72ff15408fbfcb16db41b3f9 82 Gene3D G3DSA:3.30.110.40 6 82 1.6E-9 T 23-10-2018 IPR036868 TusA-like domain superfamily VMUT_2078 a91abfed72ff15408fbfcb16db41b3f9 82 SUPERFAMILY SSF64307 4 76 1.31E-15 T 23-10-2018 IPR036868 TusA-like domain superfamily VMUT_2078 a91abfed72ff15408fbfcb16db41b3f9 82 Pfam PF01206 Sulfurtransferase TusA 7 76 6.1E-14 T 23-10-2018 IPR001455 TusA-like domain VMUT_2043 dd1d41f494d96810aca7c75c405351c9 187 Pfam PF00025 ADP-ribosylation factor family 7 149 3.9E-11 T 23-10-2018 IPR006689 Small GTPase superfamily, ARF/SAR type GO:0005525 VMUT_2043 dd1d41f494d96810aca7c75c405351c9 187 Gene3D G3DSA:3.40.50.300 5 180 3.5E-33 T 23-10-2018 VMUT_2043 dd1d41f494d96810aca7c75c405351c9 187 SUPERFAMILY SSF52540 7 172 4.12E-24 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0648 034097d922d68323c8ca59164195c903 157 Gene3D G3DSA:1.20.1260.10 6 143 1.8E-43 T 23-10-2018 IPR012347 Ferritin-like VMUT_0648 034097d922d68323c8ca59164195c903 157 SUPERFAMILY SSF47240 8 142 1.45E-36 T 23-10-2018 IPR009078 Ferritin-like superfamily VMUT_0648 034097d922d68323c8ca59164195c903 157 Pfam PF02915 Rubrerythrin 14 134 2.0E-19 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 VMUT_1569 2db287e4a7b471f569b72a9beaaff8a2 114 SUPERFAMILY SSF88723 5 105 5.89E-12 T 23-10-2018 IPR029060 PIN-like domain superfamily VMUT_1569 2db287e4a7b471f569b72a9beaaff8a2 114 Gene3D G3DSA:3.40.50.1010 1 110 1.1E-14 T 23-10-2018 VMUT_0383 dbee51aa8c21dda2c2290fbe506196bf 307 Pfam PF01012 Electron transfer flavoprotein domain 25 125 2.6E-11 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 VMUT_0383 dbee51aa8c21dda2c2290fbe506196bf 307 Gene3D G3DSA:3.40.50.1220 175 307 7.9E-49 T 23-10-2018 VMUT_0383 dbee51aa8c21dda2c2290fbe506196bf 307 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 181 263 1.5E-30 T 23-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 VMUT_0383 dbee51aa8c21dda2c2290fbe506196bf 307 PIRSF PIRSF000089 19 306 1.7E-77 T 23-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 VMUT_0383 dbee51aa8c21dda2c2290fbe506196bf 307 SUPERFAMILY SSF52467 180 301 6.0E-41 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily VMUT_0383 dbee51aa8c21dda2c2290fbe506196bf 307 Gene3D G3DSA:3.40.50.620 7 173 7.4E-16 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_0383 dbee51aa8c21dda2c2290fbe506196bf 307 SUPERFAMILY SSF52402 15 139 6.98E-14 T 23-10-2018 VMUT_0081 79736e3e281240994b6664eda9ce5b91 316 SMART SM00382 47 238 1.9E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0081 79736e3e281240994b6664eda9ce5b91 316 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 294 2.9E-19 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VMUT_0081 79736e3e281240994b6664eda9ce5b91 316 Pfam PF00005 ABC transporter 38 181 5.5E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_0081 79736e3e281240994b6664eda9ce5b91 316 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 230 313 3.8E-26 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VMUT_0081 79736e3e281240994b6664eda9ce5b91 316 SUPERFAMILY SSF52540 24 251 8.42E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0081 79736e3e281240994b6664eda9ce5b91 316 Gene3D G3DSA:3.40.50.300 24 316 4.2E-91 T 23-10-2018 VMUT_0897 75543e54e171a3972a114756c759c05c 67 Gene3D G3DSA:1.10.10.10 1 61 3.6E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_0897 75543e54e171a3972a114756c759c05c 67 Pfam PF14947 Winged helix-turn-helix 2 51 7.5E-7 T 23-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain VMUT_0897 75543e54e171a3972a114756c759c05c 67 SUPERFAMILY SSF46785 3 55 3.56E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_1251 4b08ee03658a6de26f1328148cb8ab00 401 Pfam PF13416 Bacterial extracellular solute-binding protein 25 322 1.4E-22 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein VMUT_1251 4b08ee03658a6de26f1328148cb8ab00 401 Gene3D G3DSA:3.40.190.10 117 384 6.8E-55 T 23-10-2018 VMUT_1251 4b08ee03658a6de26f1328148cb8ab00 401 Gene3D G3DSA:3.40.190.10 26 347 6.8E-55 T 23-10-2018 VMUT_1251 4b08ee03658a6de26f1328148cb8ab00 401 SUPERFAMILY SSF53850 18 385 1.6E-49 T 23-10-2018 VMUT_0373 e73d55b074e627b93c3d003a160d1ff7 275 Gene3D G3DSA:3.40.630.50 1 185 8.8E-39 T 23-10-2018 VMUT_0373 e73d55b074e627b93c3d003a160d1ff7 275 Gene3D G3DSA:3.40.50.10700 190 274 3.8E-16 T 23-10-2018 VMUT_0373 e73d55b074e627b93c3d003a160d1ff7 275 Pfam PF04414 D-aminoacyl-tRNA deacylase 68 272 3.9E-52 T 23-10-2018 IPR007508 D-aminoacyl-tRNA deacylase DtdA GO:0016788|GO:0051499 VMUT_0373 e73d55b074e627b93c3d003a160d1ff7 275 SUPERFAMILY SSF142535 1 273 7.59E-63 T 23-10-2018 VMUT_0373 e73d55b074e627b93c3d003a160d1ff7 275 PIRSF PIRSF016210 1 274 7.4E-54 T 23-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 VMUT_0534 cb75a29121109287368520e48fb553b8 250 Pfam PF06314 Acetoacetate decarboxylase (ADC) 27 247 1.1E-44 T 23-10-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 VMUT_0534 cb75a29121109287368520e48fb553b8 250 Gene3D G3DSA:2.40.400.10 15 249 6.5E-58 T 23-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 VMUT_0534 cb75a29121109287368520e48fb553b8 250 SUPERFAMILY SSF160104 10 248 7.85E-47 T 23-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 VMUT_1373 173ddb8fcff21aa40a4b47305e3c884e 318 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 291 3.1E-53 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 VMUT_1373 173ddb8fcff21aa40a4b47305e3c884e 318 SUPERFAMILY SSF51735 99 292 3.19E-52 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1373 173ddb8fcff21aa40a4b47305e3c884e 318 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 223 239 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site VMUT_1373 173ddb8fcff21aa40a4b47305e3c884e 318 SUPERFAMILY SSF52283 11 132 1.23E-30 T 23-10-2018 VMUT_1373 173ddb8fcff21aa40a4b47305e3c884e 318 Gene3D G3DSA:3.40.50.720 95 293 3.0E-98 T 23-10-2018 VMUT_1373 173ddb8fcff21aa40a4b47305e3c884e 318 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 13 313 2.2E-27 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 VMUT_1373 173ddb8fcff21aa40a4b47305e3c884e 318 Gene3D G3DSA:3.40.50.720 14 302 3.0E-98 T 23-10-2018 VMUT_1990 cc050f426d5ca34773393d91fb3788cf 135 Gene3D G3DSA:3.90.20.10 36 134 1.1E-6 T 23-10-2018 VMUT_0771 eb7a9f1105aca9d88ad69df4183633be 356 SUPERFAMILY SSF53756 24 289 4.27E-11 T 23-10-2018 VMUT_0771 eb7a9f1105aca9d88ad69df4183633be 356 Pfam PF04007 Protein of unknown function (DUF354) 4 349 8.3E-46 T 23-10-2018 IPR007152 Protein of unknown function DUF354 VMUT_0771 eb7a9f1105aca9d88ad69df4183633be 356 PIRSF PIRSF005357 3 356 9.9E-77 T 23-10-2018 IPR007152 Protein of unknown function DUF354 VMUT_1900 b3c00d18b264a7eb4793e20e6c5f4a2c 178 Pfam PF13563 2'-5' RNA ligase superfamily 26 161 3.2E-8 T 23-10-2018 VMUT_1900 b3c00d18b264a7eb4793e20e6c5f4a2c 178 SUPERFAMILY SSF55144 23 174 5.23E-13 T 23-10-2018 IPR009097 Cyclic phosphodiesterase VMUT_1900 b3c00d18b264a7eb4793e20e6c5f4a2c 178 Gene3D G3DSA:3.90.1140.10 11 177 7.8E-16 T 23-10-2018 VMUT_0962 cd80d0831b1f49c136c69c49442f3004 68 Hamap MF_00250 DNA-directed RNA polymerase subunit N [rpoN]. 1 63 21.797 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 VMUT_0962 cd80d0831b1f49c136c69c49442f3004 68 SUPERFAMILY SSF46924 1 63 9.29E-26 T 23-10-2018 IPR023580 RNA polymerase subunit RPB10 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 VMUT_0962 cd80d0831b1f49c136c69c49442f3004 68 Gene3D G3DSA:1.10.10.60 1 65 5.5E-29 T 23-10-2018 VMUT_0962 cd80d0831b1f49c136c69c49442f3004 68 PIRSF PIRSF005653 1 68 1.3E-29 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 VMUT_0962 cd80d0831b1f49c136c69c49442f3004 68 Pfam PF01194 RNA polymerases N / 8 kDa subunit 1 58 3.5E-27 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 VMUT_0962 cd80d0831b1f49c136c69c49442f3004 68 ProDom PD006539 RNA POLYMERASE DNA-DIRECTED SUBUNIT TRANSFERASE NUCLEOTIDYLTRANSFERASE METAL-BINDING ZINC TRANSCRIPTION N 10 52 7.0E-14 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 VMUT_1237 ecc33b01255b1b9b091a9e22bd9ea57d 82 SUPERFAMILY SSF81593 3 76 6.28E-14 T 23-10-2018 VMUT_1237 ecc33b01255b1b9b091a9e22bd9ea57d 82 Pfam PF05168 HEPN domain 3 76 2.1E-12 T 23-10-2018 IPR007842 HEPN domain VMUT_1237 ecc33b01255b1b9b091a9e22bd9ea57d 82 Gene3D G3DSA:1.20.120.330 1 78 1.8E-12 T 23-10-2018 VMUT_0181 614a32785fd43fb254d443ae4ee62432 297 SUPERFAMILY SSF56059 106 293 1.69E-39 T 23-10-2018 VMUT_0181 614a32785fd43fb254d443ae4ee62432 297 Gene3D G3DSA:3.30.470.80 186 296 1.1E-28 T 23-10-2018 VMUT_0181 614a32785fd43fb254d443ae4ee62432 297 Pfam PF08443 RimK-like ATP-grasp domain 104 288 4.2E-25 T 23-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 VMUT_0181 614a32785fd43fb254d443ae4ee62432 297 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 79 288 6.2E-50 T 23-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 VMUT_0181 614a32785fd43fb254d443ae4ee62432 297 Gene3D G3DSA:3.40.50.20 14 120 4.0E-8 T 23-10-2018 VMUT_1081 5f2e4d2e2e711a7c922b8f49b45a6ccb 234 SUPERFAMILY SSF52540 2 233 2.76E-15 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1081 5f2e4d2e2e711a7c922b8f49b45a6ccb 234 Gene3D G3DSA:3.40.50.300 1 234 2.2E-11 T 23-10-2018 VMUT_0628 42cd08bdefe7d42b8516d8b4de37b9b1 381 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 44 367 8.7E-19 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 VMUT_0628 42cd08bdefe7d42b8516d8b4de37b9b1 381 SUPERFAMILY SSF53649 41 379 1.26E-44 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 VMUT_0628 42cd08bdefe7d42b8516d8b4de37b9b1 381 Gene3D G3DSA:3.40.720.10 38 377 3.5E-36 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 VMUT_0646 25463a966b00ecd423b204e0f2cf11ad 397 ProSitePatterns PS00099 Thiolases active site. 378 391 - T 23-10-2018 IPR020610 Thiolase, active site GO:0016747 VMUT_0646 25463a966b00ecd423b204e0f2cf11ad 397 Gene3D G3DSA:3.40.47.10 13 280 8.2E-131 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_0646 25463a966b00ecd423b204e0f2cf11ad 397 Pfam PF00108 Thiolase, N-terminal domain 28 265 1.1E-58 T 23-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 VMUT_0646 25463a966b00ecd423b204e0f2cf11ad 397 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 14 395 4.4E-131 T 23-10-2018 IPR002155 Thiolase GO:0016747 VMUT_0646 25463a966b00ecd423b204e0f2cf11ad 397 PIRSF PIRSF000429 1 397 3.3E-122 T 23-10-2018 IPR002155 Thiolase GO:0016747 VMUT_0646 25463a966b00ecd423b204e0f2cf11ad 397 SUPERFAMILY SSF53901 8 274 9.77E-62 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_0646 25463a966b00ecd423b204e0f2cf11ad 397 ProSitePatterns PS00737 Thiolases signature 2. 343 359 - T 23-10-2018 IPR020613 Thiolase, conserved site GO:0016747 VMUT_0646 25463a966b00ecd423b204e0f2cf11ad 397 SUPERFAMILY SSF53901 275 396 7.04E-44 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_0646 25463a966b00ecd423b204e0f2cf11ad 397 Pfam PF02803 Thiolase, C-terminal domain 274 396 9.0E-48 T 23-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 VMUT_0646 25463a966b00ecd423b204e0f2cf11ad 397 Gene3D G3DSA:3.40.47.10 136 394 8.2E-131 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 VMUT_2199 1768b44aabcb3cb9f39785d2acfcdc7b 390 Gene3D G3DSA:3.40.640.10 52 278 3.0E-145 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VMUT_2199 1768b44aabcb3cb9f39785d2acfcdc7b 390 Pfam PF00155 Aminotransferase class I and II 29 379 1.1E-44 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VMUT_2199 1768b44aabcb3cb9f39785d2acfcdc7b 390 SUPERFAMILY SSF53383 6 387 3.38E-110 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VMUT_2199 1768b44aabcb3cb9f39785d2acfcdc7b 390 Gene3D G3DSA:3.90.1150.10 6 382 3.0E-145 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VMUT_1513 92862632d76d01a626d4494248557f93 353 SUPERFAMILY SSF56024 68 143 2.24E-11 T 23-10-2018 VMUT_1513 92862632d76d01a626d4494248557f93 353 Gene3D G3DSA:3.30.870.10 21 153 2.1E-12 T 23-10-2018 VMUT_1513 92862632d76d01a626d4494248557f93 353 Pfam PF13091 PLD-like domain 75 132 1.9E-11 T 23-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 VMUT_2105 57c558d8a7fa286e67255e6fef43a0b5 425 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 78 89 - T 23-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_2105 57c558d8a7fa286e67255e6fef43a0b5 425 Gene3D G3DSA:1.10.645.20 41 425 1.8E-124 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_2105 57c558d8a7fa286e67255e6fef43a0b5 425 SUPERFAMILY SSF56762 55 425 6.02E-104 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_2105 57c558d8a7fa286e67255e6fef43a0b5 425 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 156 425 8.1E-89 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_0072 71b772678a106142db0de1cf0419f770 356 Gene3D G3DSA:3.40.50.2000 1 169 1.8E-10 T 23-10-2018 VMUT_0072 71b772678a106142db0de1cf0419f770 356 Gene3D G3DSA:3.40.50.2000 170 333 5.6E-23 T 23-10-2018 VMUT_0072 71b772678a106142db0de1cf0419f770 356 Pfam PF13439 Glycosyltransferase Family 4 13 156 1.1E-8 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 VMUT_0072 71b772678a106142db0de1cf0419f770 356 SUPERFAMILY SSF53756 3 346 5.83E-33 T 23-10-2018 VMUT_0072 71b772678a106142db0de1cf0419f770 356 Pfam PF00534 Glycosyl transferases group 1 180 333 6.9E-16 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 VMUT_1732 6ed23346dfe0d92a59424060c2741c4f 94 Hamap MF_00573 50S ribosomal protein L35Ae [rpl35ae]. 8 91 18.835 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1732 6ed23346dfe0d92a59424060c2741c4f 94 SUPERFAMILY SSF50447 8 89 1.2E-10 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VMUT_1732 6ed23346dfe0d92a59424060c2741c4f 94 ProDom PD012670 RIBOSOMAL L35A 60S RIBONUCLEOPROTEIN L35A L35AE 50S RNA-BINDING TRNA-BINDING SEQUENCE 8 90 2.0E-9 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1732 6ed23346dfe0d92a59424060c2741c4f 94 Gene3D G3DSA:2.40.10.190 6 94 1.0E-14 T 23-10-2018 IPR038661 Ribosomal protein L35A superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1732 6ed23346dfe0d92a59424060c2741c4f 94 Pfam PF01247 Ribosomal protein L35Ae 8 89 1.1E-5 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_2319 2d7554ab33ecfcf7f532aa3fd0d33d37 186 SUPERFAMILY SSF53474 1 182 7.06E-34 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold VMUT_2319 2d7554ab33ecfcf7f532aa3fd0d33d37 186 Pfam PF00561 alpha/beta hydrolase fold 15 110 3.6E-10 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VMUT_2319 2d7554ab33ecfcf7f532aa3fd0d33d37 186 Gene3D G3DSA:3.40.50.1820 116 184 1.7E-13 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold VMUT_2319 2d7554ab33ecfcf7f532aa3fd0d33d37 186 Gene3D G3DSA:3.40.50.1820 1 115 5.5E-19 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold VMUT_0160 f17871c6848640dcd5b8127f2f4ab99d 126 SUPERFAMILY SSF88723 3 118 1.4E-15 T 23-10-2018 IPR029060 PIN-like domain superfamily VMUT_0160 f17871c6848640dcd5b8127f2f4ab99d 126 Pfam PF10130 PIN domain 26 113 7.4E-8 T 23-10-2018 IPR002716 PIN domain VMUT_0160 f17871c6848640dcd5b8127f2f4ab99d 126 Gene3D G3DSA:3.40.50.1010 1 126 4.6E-31 T 23-10-2018 VMUT_2006 ee0f7206ce3ea074d2853ba021331871 101 Gene3D G3DSA:3.30.70.20 6 83 1.6E-6 T 23-10-2018 VMUT_2006 ee0f7206ce3ea074d2853ba021331871 101 SUPERFAMILY SSF54862 21 84 8.37E-9 T 23-10-2018 VMUT_1539 dd1182367be00a3db7f395389767580d 58 Gene3D G3DSA:2.20.28.160 3 58 7.3E-19 T 23-10-2018 VMUT_1470 aa75c953b253209a75e7a3d795a74418 333 Pfam PF01380 SIS domain 190 283 6.9E-9 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 VMUT_1470 aa75c953b253209a75e7a3d795a74418 333 Pfam PF01380 SIS domain 21 148 6.6E-29 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 VMUT_1470 aa75c953b253209a75e7a3d795a74418 333 Gene3D G3DSA:3.40.50.10490 176 319 2.4E-88 T 23-10-2018 VMUT_1470 aa75c953b253209a75e7a3d795a74418 333 Gene3D G3DSA:3.40.50.10490 8 332 2.4E-88 T 23-10-2018 VMUT_1470 aa75c953b253209a75e7a3d795a74418 333 SUPERFAMILY SSF53697 8 332 1.95E-73 T 23-10-2018 VMUT_1850 a98fcf6efdd210a8a71cb1f452c88d54 243 SUPERFAMILY SSF56112 42 239 7.65E-17 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily VMUT_1850 a98fcf6efdd210a8a71cb1f452c88d54 243 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 50 71 - T 23-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 VMUT_1850 a98fcf6efdd210a8a71cb1f452c88d54 243 Pfam PF01163 RIO1 family 84 175 6.9E-5 T 23-10-2018 VMUT_1879 9ba31af014a8dceb4947bdbdae427314 317 SMART SM00849 37 223 7.7E-34 T 23-10-2018 IPR001279 Metallo-beta-lactamase VMUT_1879 9ba31af014a8dceb4947bdbdae427314 317 SUPERFAMILY SSF56281 21 301 1.31E-45 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_1879 9ba31af014a8dceb4947bdbdae427314 317 Gene3D G3DSA:3.60.15.10 5 245 4.2E-42 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_1879 9ba31af014a8dceb4947bdbdae427314 317 Pfam PF00753 Metallo-beta-lactamase superfamily 41 214 1.4E-28 T 23-10-2018 IPR001279 Metallo-beta-lactamase VMUT_0716 10246f1d27a4597c59115101880de0c1 64 Hamap MF_00777 30S ribosomal protein S27ae [rps27ae]. 11 59 15.477 T 23-10-2018 IPR022845 Ribosomal protein S27ae VMUT_0716 10246f1d27a4597c59115101880de0c1 64 SUPERFAMILY SSF57829 11 60 1.74E-14 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 VMUT_0716 10246f1d27a4597c59115101880de0c1 64 SMART SM01402 11 56 6.7E-21 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 VMUT_0716 10246f1d27a4597c59115101880de0c1 64 Pfam PF01599 Ribosomal protein S27a 12 56 6.5E-14 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 VMUT_0716 10246f1d27a4597c59115101880de0c1 64 Gene3D G3DSA:2.20.25.660 2 61 3.7E-10 T 23-10-2018 IPR038582 S27a-like superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 VMUT_1728 66c235209bdf0a98c734196879926212 668 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 11 423 3.9E-37 T 23-10-2018 VMUT_1728 66c235209bdf0a98c734196879926212 668 Gene3D G3DSA:2.30.310.10 7 149 8.0E-10 T 23-10-2018 VMUT_1728 66c235209bdf0a98c734196879926212 668 Pfam PF05670 Domain of unknown function (DUF814) 449 549 5.1E-23 T 23-10-2018 IPR008532 Domain of unknown function DUF814 VMUT_0786 4b881878d23c8cffde335663526bec63 135 SUPERFAMILY SSF88723 1 123 3.08E-18 T 23-10-2018 IPR029060 PIN-like domain superfamily VMUT_0786 4b881878d23c8cffde335663526bec63 135 Gene3D G3DSA:3.40.50.1010 4 133 6.5E-11 T 23-10-2018 VMUT_0786 4b881878d23c8cffde335663526bec63 135 Pfam PF01850 PIN domain 5 124 1.2E-12 T 23-10-2018 IPR002716 PIN domain VMUT_0786 4b881878d23c8cffde335663526bec63 135 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 132 10.174 T 23-10-2018 IPR022907 VapC family GO:0004540 VMUT_1390 8f9b9f8b1b4b32e693b64c9a271ba693 276 Gene3D G3DSA:3.30.70.1900 127 273 6.4E-10 T 23-10-2018 VMUT_1390 8f9b9f8b1b4b32e693b64c9a271ba693 276 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 138 265 1.6E-10 T 23-10-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal VMUT_1987 31e8e53d4f9444ace74c872a6c343020 161 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 65 82 1.2E-10 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_1987 31e8e53d4f9444ace74c872a6c343020 161 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 34 1.2E-10 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_1987 31e8e53d4f9444ace74c872a6c343020 161 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 44 63 1.2E-10 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_1987 31e8e53d4f9444ace74c872a6c343020 161 Gene3D G3DSA:3.40.50.720 1 134 1.1E-26 T 23-10-2018 VMUT_1987 31e8e53d4f9444ace74c872a6c343020 161 Pfam PF00106 short chain dehydrogenase 2 84 1.0E-18 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VMUT_1987 31e8e53d4f9444ace74c872a6c343020 161 SUPERFAMILY SSF51735 2 151 1.56E-27 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1987 31e8e53d4f9444ace74c872a6c343020 161 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 31 59 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VMUT_0805 587f8b16ed630d87a762fd86fbc01524 354 Pfam PF04055 Radical SAM superfamily 44 211 1.8E-20 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_0805 587f8b16ed630d87a762fd86fbc01524 354 SUPERFAMILY SSF102114 31 262 1.27E-37 T 23-10-2018 VMUT_0805 587f8b16ed630d87a762fd86fbc01524 354 SMART SM00729 38 255 9.2E-12 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VMUT_0805 587f8b16ed630d87a762fd86fbc01524 354 Gene3D G3DSA:3.20.20.70 33 295 3.7E-33 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_0865 08bdb2c4e75cba1d9ff7f96b6adcefd5 180 Pfam PF01931 Protein of unknown function DUF84 7 170 8.6E-43 T 23-10-2018 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 VMUT_0865 08bdb2c4e75cba1d9ff7f96b6adcefd5 180 Gene3D G3DSA:3.90.950.10 2 179 9.5E-38 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like VMUT_0865 08bdb2c4e75cba1d9ff7f96b6adcefd5 180 SUPERFAMILY SSF52972 2 173 3.31E-41 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like VMUT_0865 08bdb2c4e75cba1d9ff7f96b6adcefd5 180 TIGRFAM TIGR00258 TIGR00258: inosine/xanthosine triphosphatase 7 172 9.2E-37 T 23-10-2018 IPR002786 Non-canonical purine NTP phosphatase VMUT_0865 08bdb2c4e75cba1d9ff7f96b6adcefd5 180 Hamap MF_00648 Non-canonical purine NTP phosphatase. 2 178 29.453 T 23-10-2018 IPR002786 Non-canonical purine NTP phosphatase VMUT_1057 e577130b9c4e518e5fe55dbbe53d3885 257 Pfam PF07790 Archaeal Type IV pilin, N-terminal 5 45 3.3E-6 T 23-10-2018 IPR012859 Archaeal Type IV pilin, N-terminal VMUT_2201 4fc4513a63c9829f983971a17d8bb885 246 Gene3D G3DSA:3.20.20.220 1 243 5.1E-7 T 23-10-2018 VMUT_2201 4fc4513a63c9829f983971a17d8bb885 246 SUPERFAMILY SSF51730 2 243 9.42E-21 T 23-10-2018 IPR029041 FAD-linked oxidoreductase-like VMUT_1388 d85e0490a5a17a2cab66370309bcd07f 332 SUPERFAMILY SSF56300 4 328 5.87E-59 T 23-10-2018 VMUT_1388 d85e0490a5a17a2cab66370309bcd07f 332 Gene3D G3DSA:3.60.21.10 96 325 4.9E-20 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like VMUT_1388 d85e0490a5a17a2cab66370309bcd07f 332 Pfam PF00149 Calcineurin-like phosphoesterase 4 283 1.0E-5 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 VMUT_1795 636b82e018c70032227c6eebdcf3a146 225 Pfam PF11010 Protein of unknown function (DUF2848) 30 222 3.4E-63 T 23-10-2018 IPR021269 Protein of unknown function DUF2848 VMUT_1651 c7934e0db6757672bbeb8329ba9b98d1 162 SUPERFAMILY SSF53271 2 136 4.85E-31 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like VMUT_1651 c7934e0db6757672bbeb8329ba9b98d1 162 Gene3D G3DSA:3.40.50.2020 1 153 4.4E-36 T 23-10-2018 VMUT_1651 c7934e0db6757672bbeb8329ba9b98d1 162 Pfam PF00156 Phosphoribosyl transferase domain 3 126 1.2E-20 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 VMUT_1763 b676425a8f91d6242400a0549782d0d9 479 ProSitePatterns PS00756 Protein secY signature 2. 166 184 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 VMUT_1763 b676425a8f91d6242400a0549782d0d9 479 SUPERFAMILY SSF103491 10 459 1.7E-79 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 VMUT_1763 b676425a8f91d6242400a0549782d0d9 479 ProSitePatterns PS00755 Protein secY signature 1. 79 98 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 VMUT_1763 b676425a8f91d6242400a0549782d0d9 479 Pfam PF00344 SecY translocase 79 457 4.1E-58 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 VMUT_1763 b676425a8f91d6242400a0549782d0d9 479 PIRSF PIRSF004557 9 479 2.4E-82 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 VMUT_1763 b676425a8f91d6242400a0549782d0d9 479 Gene3D G3DSA:1.10.3370.10 9 478 2.5E-114 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 VMUT_0969 85f354707a1aca42aac54f80c422c969 190 Gene3D G3DSA:3.60.21.10 91 186 2.1E-32 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like VMUT_0969 85f354707a1aca42aac54f80c422c969 190 SUPERFAMILY SSF56300 3 181 2.19E-51 T 23-10-2018 VMUT_0969 85f354707a1aca42aac54f80c422c969 190 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 4 179 4.3E-20 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 VMUT_0969 85f354707a1aca42aac54f80c422c969 190 Gene3D G3DSA:3.60.21.10 3 86 7.0E-7 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like VMUT_0920 fb90c601743744b76ddb9b8a906c9f94 332 Pfam PF01032 FecCD transport family 19 327 7.5E-69 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 VMUT_0920 fb90c601743744b76ddb9b8a906c9f94 332 SUPERFAMILY SSF81345 10 327 5.89E-60 T 23-10-2018 IPR037294 ABC transporter, BtuC-like VMUT_0920 fb90c601743744b76ddb9b8a906c9f94 332 Gene3D G3DSA:1.10.3470.10 4 330 1.6E-74 T 23-10-2018 IPR037294 ABC transporter, BtuC-like VMUT_1410 28e4466fa0d33831667e756d2a2ac728 397 Pfam PF01458 Uncharacterized protein family (UPF0051) 154 364 5.2E-31 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 VMUT_1410 28e4466fa0d33831667e756d2a2ac728 397 SUPERFAMILY SSF101960 3 381 1.83E-48 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily VMUT_0588 79ec1eecf1b9ec18c5ee3d2d26f809fc 121 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 2 120 2.8E-41 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 VMUT_0588 79ec1eecf1b9ec18c5ee3d2d26f809fc 121 TIGRFAM TIGR00283 arch_pth2: peptidyl-tRNA hydrolase 3 120 3.5E-37 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 VMUT_0588 79ec1eecf1b9ec18c5ee3d2d26f809fc 121 Hamap MF_00628 Peptidyl-tRNA hydrolase [pth]. 2 121 30.782 T 23-10-2018 IPR034759 Peptidyl-tRNA hydrolase, archaea GO:0004045 MetaCyc: PWY-6308 VMUT_0588 79ec1eecf1b9ec18c5ee3d2d26f809fc 121 Gene3D G3DSA:3.40.1490.10 1 120 1.8E-44 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 VMUT_0588 79ec1eecf1b9ec18c5ee3d2d26f809fc 121 SUPERFAMILY SSF102462 2 120 5.58E-42 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 VMUT_2223 6ffd551b4fe4ab564575a0c74b0bbae8 358 Gene3D G3DSA:3.20.20.70 1 358 8.7E-122 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_2223 6ffd551b4fe4ab564575a0c74b0bbae8 358 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 2 337 37.128 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 VMUT_2223 6ffd551b4fe4ab564575a0c74b0bbae8 358 PIRSF PIRSF003314 1 348 2.4E-118 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 VMUT_2223 6ffd551b4fe4ab564575a0c74b0bbae8 358 SUPERFAMILY SSF51395 23 349 1.88E-76 T 23-10-2018 VMUT_2223 6ffd551b4fe4ab564575a0c74b0bbae8 358 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 4 336 5.1E-116 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 VMUT_2223 6ffd551b4fe4ab564575a0c74b0bbae8 358 Pfam PF01070 FMN-dependent dehydrogenase 14 332 2.3E-19 T 23-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 VMUT_1085 acca7d8016b4e046fd811b5042012565 353 Gene3D G3DSA:3.90.550.10 13 202 1.2E-11 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1085 acca7d8016b4e046fd811b5042012565 353 SUPERFAMILY SSF53448 25 263 3.47E-14 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1085 acca7d8016b4e046fd811b5042012565 353 Pfam PF00535 Glycosyl transferase family 2 32 138 5.3E-9 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VMUT_0914 4ce6ab62430d2a03cd989366fff95d74 387 Hamap MF_00900 GTPase HflX [hflX]. 38 387 38.537 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 VMUT_0914 4ce6ab62430d2a03cd989366fff95d74 387 PIRSF PIRSF006809 8 382 9.1E-103 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 VMUT_0914 4ce6ab62430d2a03cd989366fff95d74 387 Gene3D G3DSA:3.40.50.300 206 379 3.2E-35 T 23-10-2018 VMUT_0914 4ce6ab62430d2a03cd989366fff95d74 387 Pfam PF13167 GTP-binding GTPase N-terminal 36 121 1.5E-22 T 23-10-2018 IPR025121 GTPase HflX, N-terminal VMUT_0914 4ce6ab62430d2a03cd989366fff95d74 387 Pfam PF16360 GTP-binding GTPase Middle Region 124 200 5.5E-16 T 23-10-2018 IPR032305 GTP-binding protein, middle domain VMUT_0914 4ce6ab62430d2a03cd989366fff95d74 387 Gene3D G3DSA:3.40.50.11060 29 150 1.9E-28 T 23-10-2018 VMUT_0914 4ce6ab62430d2a03cd989366fff95d74 387 Pfam PF01926 50S ribosome-binding GTPase 208 306 3.5E-15 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 VMUT_0914 4ce6ab62430d2a03cd989366fff95d74 387 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 275 293 3.3E-5 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 VMUT_0914 4ce6ab62430d2a03cd989366fff95d74 387 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 209 229 3.3E-5 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 VMUT_0914 4ce6ab62430d2a03cd989366fff95d74 387 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 230 248 3.3E-5 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 VMUT_0914 4ce6ab62430d2a03cd989366fff95d74 387 SUPERFAMILY SSF52540 206 375 2.34E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0914 4ce6ab62430d2a03cd989366fff95d74 387 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 35 372 3.8E-90 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 VMUT_1203 3769f3715fe250f69c5380d6895cc76a 422 Pfam PF02754 Cysteine-rich domain 304 386 3.4E-8 T 23-10-2018 IPR004017 Cysteine-rich domain VMUT_1203 3769f3715fe250f69c5380d6895cc76a 422 Pfam PF02754 Cysteine-rich domain 181 262 1.9E-9 T 23-10-2018 IPR004017 Cysteine-rich domain VMUT_1203 3769f3715fe250f69c5380d6895cc76a 422 SUPERFAMILY SSF54862 18 115 1.21E-17 T 23-10-2018 VMUT_1203 3769f3715fe250f69c5380d6895cc76a 422 Pfam PF13183 4Fe-4S dicluster domain 19 86 2.2E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VMUT_1203 3769f3715fe250f69c5380d6895cc76a 422 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 72 83 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_1203 3769f3715fe250f69c5380d6895cc76a 422 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 21 32 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_1203 3769f3715fe250f69c5380d6895cc76a 422 Gene3D G3DSA:1.10.1060.10 11 98 4.7E-7 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VMUT_1203 3769f3715fe250f69c5380d6895cc76a 422 PIRSF PIRSF000139 3 419 8.2E-98 T 23-10-2018 VMUT_0911 6b615ce9cdf86a220e5913318d23fbb3 155 Hamap MF_00308 Prefoldin subunit alpha [pfdA]. 14 147 12.403 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 VMUT_0911 6b615ce9cdf86a220e5913318d23fbb3 155 TIGRFAM TIGR00293 TIGR00293: prefoldin, alpha subunit 19 138 6.1E-21 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 VMUT_0911 6b615ce9cdf86a220e5913318d23fbb3 155 Gene3D G3DSA:1.10.287.370 18 148 1.5E-26 T 23-10-2018 IPR009053 Prefoldin VMUT_0911 6b615ce9cdf86a220e5913318d23fbb3 155 Pfam PF02996 Prefoldin subunit 34 137 1.4E-15 T 23-10-2018 IPR004127 Prefoldin alpha-like VMUT_0911 6b615ce9cdf86a220e5913318d23fbb3 155 SUPERFAMILY SSF46579 19 137 1.15E-19 T 23-10-2018 VMUT_0850 1575378e8117db37de9f7351fbc08e4c 367 Gene3D G3DSA:3.40.50.10540 5 333 1.3E-118 T 23-10-2018 IPR023606 CoA-transferase family III domain superfamily VMUT_0850 1575378e8117db37de9f7351fbc08e4c 367 SUPERFAMILY SSF89796 4 361 1.96E-119 T 23-10-2018 IPR023606 CoA-transferase family III domain superfamily VMUT_0850 1575378e8117db37de9f7351fbc08e4c 367 Pfam PF02515 CoA-transferase family III 6 363 1.2E-112 T 23-10-2018 IPR003673 CoA-transferase family III GO:0003824 VMUT_0850 1575378e8117db37de9f7351fbc08e4c 367 Gene3D G3DSA:3.30.1540.10 226 319 1.3E-118 T 23-10-2018 VMUT_1194 8d1b92d4b306b6b76d95035d4391d3f8 167 Pfam PF05916 GINS complex protein 43 145 6.8E-5 T 23-10-2018 IPR021151 GINS subunit, domain A Reactome: R-HSA-176974 VMUT_1258 41ee5ccd25910ebb481e191e1575506f 287 Gene3D G3DSA:1.10.3720.10 42 281 5.8E-45 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_1258 41ee5ccd25910ebb481e191e1575506f 287 SUPERFAMILY SSF161098 48 272 5.36E-43 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_1258 41ee5ccd25910ebb481e191e1575506f 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 277 4.4E-11 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VMUT_0368 eb72bea609a88fb9a4d621e38df85754 461 SUPERFAMILY SSF53448 49 317 2.82E-31 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0368 eb72bea609a88fb9a4d621e38df85754 461 Gene3D G3DSA:3.90.550.10 40 258 2.6E-24 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0368 eb72bea609a88fb9a4d621e38df85754 461 Pfam PF13632 Glycosyl transferase family group 2 138 337 2.4E-16 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VMUT_1962 927f31e32513ba8e24f57a48e9028a4f 374 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 2 367 4.3E-126 T 23-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VMUT_1962 927f31e32513ba8e24f57a48e9028a4f 374 Gene3D G3DSA:3.30.1490.20 21 95 4.4E-72 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VMUT_1962 927f31e32513ba8e24f57a48e9028a4f 374 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 373 35.328 T 23-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VMUT_1962 927f31e32513ba8e24f57a48e9028a4f 374 Pfam PF08442 ATP-grasp domain 3 193 6.7E-52 T 23-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VMUT_1962 927f31e32513ba8e24f57a48e9028a4f 374 Pfam PF00549 CoA-ligase 252 367 1.2E-19 T 23-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VMUT_1962 927f31e32513ba8e24f57a48e9028a4f 374 PIRSF PIRSF001554 1 374 4.2E-128 T 23-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VMUT_1962 927f31e32513ba8e24f57a48e9028a4f 374 SUPERFAMILY SSF56059 3 220 2.29E-58 T 23-10-2018 VMUT_1962 927f31e32513ba8e24f57a48e9028a4f 374 SUPERFAMILY SSF52210 231 368 4.06E-46 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VMUT_1962 927f31e32513ba8e24f57a48e9028a4f 374 Gene3D G3DSA:3.40.50.261 230 372 2.7E-50 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VMUT_1962 927f31e32513ba8e24f57a48e9028a4f 374 Gene3D G3DSA:3.30.470.20 2 221 4.4E-72 T 23-10-2018 VMUT_1921 c3cbc552c2b81ca4fc8c1d3dcf50f85e 81 SUPERFAMILY SSF52540 2 73 6.59E-11 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1921 c3cbc552c2b81ca4fc8c1d3dcf50f85e 81 Gene3D G3DSA:3.40.50.300 1 71 2.1E-13 T 23-10-2018 VMUT_0328 84958a9bb24f8d7fdbd635d1edff9427 167 Pfam PF07690 Major Facilitator Superfamily 2 150 7.9E-18 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_0328 84958a9bb24f8d7fdbd635d1edff9427 167 SUPERFAMILY SSF103473 2 146 1.96E-19 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_0328 84958a9bb24f8d7fdbd635d1edff9427 167 Gene3D G3DSA:1.20.1250.20 1 167 3.7E-19 T 23-10-2018 VMUT_2133 8e97017c4f9eb2f15eaaaf7f9d185cd2 484 Gene3D G3DSA:3.40.50.300 272 484 2.6E-24 T 23-10-2018 VMUT_2133 8e97017c4f9eb2f15eaaaf7f9d185cd2 484 Gene3D G3DSA:3.40.50.300 120 225 2.8E-13 T 23-10-2018 VMUT_2133 8e97017c4f9eb2f15eaaaf7f9d185cd2 484 Pfam PF01935 Domain of unknown function DUF87 132 350 7.3E-20 T 23-10-2018 IPR002789 Helicase HerA, central domain VMUT_2133 8e97017c4f9eb2f15eaaaf7f9d185cd2 484 SMART SM00382 151 429 0.0071 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_2133 8e97017c4f9eb2f15eaaaf7f9d185cd2 484 SUPERFAMILY SSF52540 129 476 4.15E-30 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0983 81ad0e37bcaf0666b0f423067a4c0c1e 100 SUPERFAMILY SSF81333 34 99 3.01E-14 T 23-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily VMUT_0983 81ad0e37bcaf0666b0f423067a4c0c1e 100 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 51 77 3.5E-10 T 23-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 VMUT_0983 81ad0e37bcaf0666b0f423067a4c0c1e 100 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 78 100 3.5E-10 T 23-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 VMUT_0983 81ad0e37bcaf0666b0f423067a4c0c1e 100 Gene3D G3DSA:1.20.120.610 1 100 8.6E-14 T 23-10-2018 VMUT_0983 81ad0e37bcaf0666b0f423067a4c0c1e 100 Pfam PF00137 ATP synthase subunit C 40 99 7.7E-16 T 23-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 VMUT_0796 4a0eb10b3513dfae5b43216974c4c5e0 375 SUPERFAMILY SSF47240 12 140 2.54E-13 T 23-10-2018 IPR009078 Ferritin-like superfamily VMUT_0796 4a0eb10b3513dfae5b43216974c4c5e0 375 Pfam PF02915 Rubrerythrin 14 137 3.3E-6 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 VMUT_0796 4a0eb10b3513dfae5b43216974c4c5e0 375 Pfam PF01988 VIT family 149 363 1.9E-36 T 23-10-2018 IPR008217 Ccc1 family VMUT_0171 ed44eb84d3f1047d4f33c8e669e46a53 182 SUPERFAMILY SSF46785 115 178 1.17E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0171 ed44eb84d3f1047d4f33c8e669e46a53 182 Pfam PF12802 MarR family 118 166 2.8E-6 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VMUT_0171 ed44eb84d3f1047d4f33c8e669e46a53 182 Gene3D G3DSA:1.10.10.10 114 181 2.4E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_1287 21f91a1073c5466a022fa6c8d3d727f2 289 SUPERFAMILY SSF46785 221 285 4.26E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_1287 21f91a1073c5466a022fa6c8d3d727f2 289 Gene3D G3DSA:1.10.10.10 213 285 4.1E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_1287 21f91a1073c5466a022fa6c8d3d727f2 289 Pfam PF13412 Winged helix-turn-helix DNA-binding 222 270 2.0E-7 T 23-10-2018 VMUT_1092 0e0fdd271c86fb4ef5d5a255d4acb0aa 310 Gene3D G3DSA:3.90.25.10 176 301 1.5E-96 T 23-10-2018 VMUT_1092 0e0fdd271c86fb4ef5d5a255d4acb0aa 310 Gene3D G3DSA:3.40.50.720 5 237 1.5E-96 T 23-10-2018 VMUT_1092 0e0fdd271c86fb4ef5d5a255d4acb0aa 310 SUPERFAMILY SSF51735 2 306 3.11E-90 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_1092 0e0fdd271c86fb4ef5d5a255d4acb0aa 310 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 237 3.0E-59 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 VMUT_0932 2a6018c3e1fe990876c08f51d42992f0 61 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 42 1.1E-10 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 VMUT_0932 2a6018c3e1fe990876c08f51d42992f0 61 Gene3D G3DSA:1.10.1220.10 8 44 5.0E-10 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 VMUT_0932 2a6018c3e1fe990876c08f51d42992f0 61 SUPERFAMILY SSF47598 1 44 2.08E-12 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 VMUT_0957 5789f23611c630934fc073d50fce94af 435 SUPERFAMILY SSF103473 19 426 3.4E-39 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_0957 5789f23611c630934fc073d50fce94af 435 Pfam PF00083 Sugar (and other) transporter 27 218 3.4E-14 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VMUT_0957 5789f23611c630934fc073d50fce94af 435 Gene3D G3DSA:1.20.1250.20 15 434 2.1E-41 T 23-10-2018 VMUT_1005 4a8c1ae006d738bfdbe84df9bb1f6fb7 272 SUPERFAMILY SSF52540 11 259 1.36E-18 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1005 4a8c1ae006d738bfdbe84df9bb1f6fb7 272 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 13 242 4.5E-10 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain VMUT_1005 4a8c1ae006d738bfdbe84df9bb1f6fb7 272 Gene3D G3DSA:3.40.50.300 10 264 6.4E-19 T 23-10-2018 VMUT_1070 6f817f06fd6ff69c478a7d9077315b54 428 SUPERFAMILY SSF53649 2 335 1.07E-33 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 VMUT_1070 6f817f06fd6ff69c478a7d9077315b54 428 Pfam PF00884 Sulfatase 4 332 5.1E-12 T 23-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 VMUT_1070 6f817f06fd6ff69c478a7d9077315b54 428 Gene3D G3DSA:3.40.720.10 269 345 3.2E-13 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 VMUT_1070 6f817f06fd6ff69c478a7d9077315b54 428 Gene3D G3DSA:3.40.720.10 2 259 1.8E-19 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 VMUT_1446 c6e9d59afe6ece00774b0a7be911f97e 167 Pfam PF06195 Protein of unknown function (DUF996) 26 156 1.1E-33 T 23-10-2018 IPR010397 Protein of unknown function DUF996 VMUT_0880 2c7ced53eec7464d6be5f6190ecd50eb 179 Pfam PF02926 THUMP domain 48 159 4.3E-16 T 23-10-2018 IPR004114 THUMP domain GO:0003723 VMUT_0880 2c7ced53eec7464d6be5f6190ecd50eb 179 SUPERFAMILY SSF143437 71 159 1.27E-14 T 23-10-2018 VMUT_0880 2c7ced53eec7464d6be5f6190ecd50eb 179 SMART SM00981 75 160 5.4E-13 T 23-10-2018 IPR004114 THUMP domain GO:0003723 VMUT_0880 2c7ced53eec7464d6be5f6190ecd50eb 179 Gene3D G3DSA:3.30.2300.10 84 160 2.0E-10 T 23-10-2018 VMUT_0302 dd589cefe4875759a5a2658992d70fc9 234 Pfam PF09754 PAC2 family 10 221 5.3E-37 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 VMUT_0302 dd589cefe4875759a5a2658992d70fc9 234 SUPERFAMILY SSF159659 3 225 9.68E-23 T 23-10-2018 VMUT_0302 dd589cefe4875759a5a2658992d70fc9 234 Gene3D G3DSA:3.40.50.10900 1 231 4.1E-38 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily VMUT_1259 e500457a97bf35c427990145c01a8995 290 SUPERFAMILY SSF161098 9 281 6.82E-45 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_1259 e500457a97bf35c427990145c01a8995 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 280 1.6E-17 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VMUT_1259 e500457a97bf35c427990145c01a8995 290 Gene3D G3DSA:1.10.3720.10 4 274 8.5E-40 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_1326 244d43ca5d4c187cb5b0228046949a15 178 SUPERFAMILY SSF52540 3 170 6.05E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1326 244d43ca5d4c187cb5b0228046949a15 178 Gene3D G3DSA:3.40.50.300 3 175 6.5E-39 T 23-10-2018 VMUT_1326 244d43ca5d4c187cb5b0228046949a15 178 Pfam PF13207 AAA domain 7 124 1.1E-14 T 23-10-2018 VMUT_2108 51774bbdd94f046d2e801d69a3227888 423 SUPERFAMILY SSF52540 104 216 2.1E-7 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0912 9c26c23cfb7898198d6c3df163929e30 85 ProDom PD010302 RIBOSOMAL LX 50S RIBONUCLEOPROTEIN HL32 DIRECT SEQUENCING LXA LSU 23 60 8.0E-7 T 23-10-2018 IPR002768 50S ribosomal protein L18Ae, archaea GO:0003735|GO:0005840|GO:0006412 VMUT_0912 9c26c23cfb7898198d6c3df163929e30 85 Gene3D G3DSA:3.10.20.10 6 80 1.0E-24 T 23-10-2018 VMUT_0912 9c26c23cfb7898198d6c3df163929e30 85 Hamap MF_00273 50S ribosomal protein L18Ae [rpl18a]. 6 61 16.492 T 23-10-2018 IPR028877 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0912 9c26c23cfb7898198d6c3df163929e30 85 SUPERFAMILY SSF160374 5 78 6.93E-22 T 23-10-2018 VMUT_0912 9c26c23cfb7898198d6c3df163929e30 85 Pfam PF01775 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A 5 61 5.3E-11 T 23-10-2018 IPR023573 Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0218 3a4e8a128023df826deee8b4a15dba01 81 SUPERFAMILY SSF54285 10 77 3.49E-12 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp VMUT_0218 3a4e8a128023df826deee8b4a15dba01 81 Gene3D G3DSA:3.10.20.30 1 79 3.9E-16 T 23-10-2018 IPR012675 Beta-grasp domain superfamily VMUT_0218 3a4e8a128023df826deee8b4a15dba01 81 Pfam PF02597 ThiS family 6 77 1.8E-8 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 VMUT_1208 4583c6e32f454274676470ad86ff874f 263 Pfam PF00483 Nucleotidyl transferase 4 252 9.3E-30 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 VMUT_1208 4583c6e32f454274676470ad86ff874f 263 SUPERFAMILY SSF53448 4 255 1.56E-47 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1208 4583c6e32f454274676470ad86ff874f 263 Gene3D G3DSA:3.90.550.10 4 262 1.7E-53 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1602 108ee161f4c41aa42b72221733b0edac 538 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 41 464 4.7E-61 T 23-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 VMUT_1602 108ee161f4c41aa42b72221733b0edac 538 Gene3D G3DSA:1.10.4160.10 24 521 3.0E-93 T 23-10-2018 IPR038271 Purine-cytosine permease superfamily VMUT_1147 98073c7ebb2e7bc6eb747350542e4f00 303 SUPERFAMILY SSF58100 18 109 4.18E-6 T 23-10-2018 VMUT_1147 98073c7ebb2e7bc6eb747350542e4f00 303 Gene3D G3DSA:1.20.5.340 30 115 6.9E-6 T 23-10-2018 VMUT_2049 3fafdf7d477909be065a07b6636ba88f 183 Gene3D G3DSA:3.40.630.30 26 183 4.4E-45 T 23-10-2018 VMUT_2049 3fafdf7d477909be065a07b6636ba88f 183 Pfam PF00583 Acetyltransferase (GNAT) family 49 157 1.0E-14 T 23-10-2018 IPR000182 GNAT domain VMUT_2049 3fafdf7d477909be065a07b6636ba88f 183 SUPERFAMILY SSF55729 27 181 5.23E-29 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase VMUT_1178 881b51f5d8049dda5bd85d132753170f 492 SUPERFAMILY SSF53720 12 490 1.7E-129 T 23-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VMUT_1178 881b51f5d8049dda5bd85d132753170f 492 Gene3D G3DSA:3.40.605.10 33 469 1.4E-127 T 23-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VMUT_1178 881b51f5d8049dda5bd85d132753170f 492 Pfam PF00171 Aldehyde dehydrogenase family 21 485 5.2E-119 T 23-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VMUT_1178 881b51f5d8049dda5bd85d132753170f 492 Gene3D G3DSA:3.40.309.10 258 461 1.4E-127 T 23-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VMUT_0853 0886d53f12b90d9685e943cde0fceb8e 198 SUPERFAMILY SSF55021 4 68 2.1E-8 T 23-10-2018 VMUT_0853 0886d53f12b90d9685e943cde0fceb8e 198 Gene3D G3DSA:3.30.70.260 3 71 2.9E-5 T 23-10-2018 VMUT_1860 cb06831db3e2d80158b5f8ad4b1e26bc 441 SUPERFAMILY SSF53300 277 395 5.82E-11 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily VMUT_1860 cb06831db3e2d80158b5f8ad4b1e26bc 441 Gene3D G3DSA:3.40.50.410 275 437 6.4E-8 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily VMUT_1277 d5ad8c23fdb684d2f58cdb66f676cd9b 179 Pfam PF01864 CDP-archaeol synthase 9 179 6.2E-44 T 23-10-2018 IPR032690 CDP-archaeol synthase KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 VMUT_1277 d5ad8c23fdb684d2f58cdb66f676cd9b 179 Hamap MF_01117 CDP-archaeol synthase [carS]. 14 179 26.337 T 23-10-2018 IPR002726 CDP-archaeol synthase, archaea KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 VMUT_2196 4b22a1734dc8acfbd1a95ce224c2d2e2 662 Pfam PF07670 Nucleoside recognition 500 629 3.0E-21 T 23-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 VMUT_2196 4b22a1734dc8acfbd1a95ce224c2d2e2 662 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 15 623 1.1E-126 T 23-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 VMUT_2196 4b22a1734dc8acfbd1a95ce224c2d2e2 662 SUPERFAMILY SSF52540 9 168 2.58E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_2196 4b22a1734dc8acfbd1a95ce224c2d2e2 662 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 164 1.4E-15 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 VMUT_2196 4b22a1734dc8acfbd1a95ce224c2d2e2 662 Pfam PF02421 Ferrous iron transport protein B 9 163 4.0E-43 T 23-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 VMUT_2196 4b22a1734dc8acfbd1a95ce224c2d2e2 662 Gene3D G3DSA:3.40.50.300 8 186 4.0E-33 T 23-10-2018 VMUT_1093 9f8b8be85cd5fd5efe11fad5d0aae38c 375 Pfam PF13439 Glycosyltransferase Family 4 14 178 4.3E-15 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 VMUT_1093 9f8b8be85cd5fd5efe11fad5d0aae38c 375 Pfam PF00534 Glycosyl transferases group 1 200 356 2.0E-30 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 VMUT_1093 9f8b8be85cd5fd5efe11fad5d0aae38c 375 Gene3D G3DSA:3.40.50.2000 1 185 5.5E-26 T 23-10-2018 VMUT_1093 9f8b8be85cd5fd5efe11fad5d0aae38c 375 Gene3D G3DSA:3.40.50.2000 186 358 2.3E-38 T 23-10-2018 VMUT_1093 9f8b8be85cd5fd5efe11fad5d0aae38c 375 SUPERFAMILY SSF53756 1 373 3.3E-69 T 23-10-2018 VMUT_0012 278331b95249bce9c9ad3d134a84b457 797 Pfam PF05317 Thermopsin 176 436 1.2E-64 T 23-10-2018 IPR007981 Peptidase A5, thermopsin VMUT_0704 6c23f5f17cb3458c19233d88961d516f 467 Gene3D G3DSA:3.40.50.300 25 111 1.4E-5 T 23-10-2018 VMUT_0704 6c23f5f17cb3458c19233d88961d516f 467 Gene3D G3DSA:3.40.50.300 164 351 1.8E-6 T 23-10-2018 VMUT_0704 6c23f5f17cb3458c19233d88961d516f 467 Pfam PF01935 Domain of unknown function DUF87 43 167 3.8E-9 T 23-10-2018 IPR002789 Helicase HerA, central domain VMUT_0704 6c23f5f17cb3458c19233d88961d516f 467 SUPERFAMILY SSF52540 35 269 1.14E-15 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1364 f75d2206f7d2aaf829c7e2e8faa8ac50 694 Gene3D G3DSA:3.40.720.10 48 200 5.4E-23 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 VMUT_1364 f75d2206f7d2aaf829c7e2e8faa8ac50 694 Gene3D G3DSA:3.40.720.10 251 403 1.4E-35 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 VMUT_1364 f75d2206f7d2aaf829c7e2e8faa8ac50 694 Pfam PF04185 Phosphoesterase family 59 374 8.4E-67 T 23-10-2018 IPR007312 Phosphoesterase GO:0016788 VMUT_1667 c5e886ff7e096792a905798bbefc0769 272 Gene3D G3DSA:1.10.10.10 7 85 1.3E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_1667 c5e886ff7e096792a905798bbefc0769 272 SUPERFAMILY SSF46785 15 85 2.38E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_1667 c5e886ff7e096792a905798bbefc0769 272 Pfam PF01022 Bacterial regulatory protein, arsR family 15 60 1.4E-4 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VMUT_1835 70aa959b3b326910e84f86e7b61cbc21 186 Pfam PF14321 Domain of unknown function (DUF4382) 42 176 3.2E-22 T 23-10-2018 IPR025491 Domain of unknown function DUF4382 VMUT_0246 4643d889b49541355456598aba7fc984 443 Gene3D G3DSA:3.40.1480.10 275 433 2.2E-130 T 23-10-2018 IPR037035 Glycerate kinase-like, C-terminal domain superfamily VMUT_0246 4643d889b49541355456598aba7fc984 443 Pfam PF05161 MOFRL family 331 433 4.0E-27 T 23-10-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 VMUT_0246 4643d889b49541355456598aba7fc984 443 SUPERFAMILY SSF82544 52 440 3.53E-118 T 23-10-2018 VMUT_0246 4643d889b49541355456598aba7fc984 443 Gene3D G3DSA:3.40.50.10180 40 274 2.2E-130 T 23-10-2018 IPR038614 Glycerate kinase, N-terminal domain superfamily Reactome: R-HSA-70350 VMUT_0246 4643d889b49541355456598aba7fc984 443 Pfam PF13660 Domain of unknown function (DUF4147) 46 251 4.7E-71 T 23-10-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 VMUT_2235 02115b81e8d0dd0f262c55de2faeeaf4 390 Pfam PF00083 Sugar (and other) transporter 7 203 5.2E-16 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VMUT_2235 02115b81e8d0dd0f262c55de2faeeaf4 390 Gene3D G3DSA:1.20.1250.20 2 389 1.8E-41 T 23-10-2018 VMUT_2235 02115b81e8d0dd0f262c55de2faeeaf4 390 SUPERFAMILY SSF103473 4 387 1.14E-38 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_0767 d621e49b84367da8a01336f9b30b52dc 62 ProDom PD005132 RIBOSOMAL RRNA-BINDING METAL-BINDING RNA-BINDING ZINC RIBONUCLEOPROTEIN ZINC-FINGER L37 60S L37E 9 51 4.0E-12 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0767 d621e49b84367da8a01336f9b30b52dc 62 SUPERFAMILY SSF57829 1 56 7.32E-20 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 VMUT_0767 d621e49b84367da8a01336f9b30b52dc 62 ProSitePatterns PS01077 Ribosomal protein L37e signature. 4 24 - T 23-10-2018 IPR018267 Ribosomal protein L37e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0767 d621e49b84367da8a01336f9b30b52dc 62 Pfam PF01907 Ribosomal protein L37e 3 55 5.0E-21 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0767 d621e49b84367da8a01336f9b30b52dc 62 Hamap MF_00547 50S ribosomal protein L37e [rpl37e]. 2 55 19.428 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0767 d621e49b84367da8a01336f9b30b52dc 62 Gene3D G3DSA:2.20.25.30 1 56 1.7E-19 T 23-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_1618 af097067dd898fa7fce8d046f5b7faa5 193 Pfam PF03367 ZPR1 zinc-finger domain 19 174 2.8E-32 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 VMUT_1618 af097067dd898fa7fce8d046f5b7faa5 193 TIGRFAM TIGR00340 zpr1_rel: zinc finger protein ZPR1 homolog 20 175 4.2E-38 T 23-10-2018 IPR004470 Zinc finger, ZPR1-type, subgroup GO:0008270 VMUT_1618 af097067dd898fa7fce8d046f5b7faa5 193 TIGRFAM TIGR00310 ZPR1_znf: ZPR1 zinc finger domain 19 177 2.9E-37 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 VMUT_1618 af097067dd898fa7fce8d046f5b7faa5 193 SMART SM00709 18 176 5.4E-27 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 VMUT_1618 af097067dd898fa7fce8d046f5b7faa5 193 Gene3D G3DSA:2.60.120.1040 64 190 3.3E-19 T 23-10-2018 VMUT_1951 c68e4a1624af58bfb059fdb59d277d3b 116 SUPERFAMILY SSF89447 68 96 3.31E-5 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily VMUT_1951 c68e4a1624af58bfb059fdb59d277d3b 116 Gene3D G3DSA:2.10.260.10 14 105 7.9E-12 T 23-10-2018 VMUT_0353 91fb5c9fe76ec883a85388b8982952ce 79 Pfam PF05942 Archaeal PaREP1/PaREP8 family 5 70 1.5E-10 T 23-10-2018 IPR010268 Archaeal PaREP1 VMUT_0422 7a024ef574efee08c94dae7927e4753a 209 SUPERFAMILY SSF82114 81 207 3.6E-45 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 VMUT_0422 7a024ef574efee08c94dae7927e4753a 209 Gene3D G3DSA:2.40.30.30 78 209 1.3E-47 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 VMUT_0422 7a024ef574efee08c94dae7927e4753a 209 Pfam PF01982 Domain of unknown function DUF120 87 206 7.1E-44 T 23-10-2018 IPR023602 Riboflavin kinase domain, CTP-dependent GO:0016773 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 VMUT_1285 8911b477788d7c225bc413bcb80062c0 232 Gene3D G3DSA:1.10.150.520 14 92 2.8E-18 T 23-10-2018 VMUT_1285 8911b477788d7c225bc413bcb80062c0 232 Pfam PF12710 haloacid dehalogenase-like hydrolase 3 140 4.0E-6 T 23-10-2018 VMUT_1285 8911b477788d7c225bc413bcb80062c0 232 Gene3D G3DSA:3.40.50.1000 3 187 2.8E-18 T 23-10-2018 IPR023214 HAD superfamily VMUT_1285 8911b477788d7c225bc413bcb80062c0 232 SUPERFAMILY SSF56784 3 216 4.49E-23 T 23-10-2018 IPR036412 HAD-like superfamily VMUT_0909 c313aed35074042ce554eee28fb4dc1f 91 SUPERFAMILY SSF103456 7 50 3.4E-6 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 VMUT_0909 c313aed35074042ce554eee28fb4dc1f 91 Gene3D G3DSA:1.20.5.820 1 55 5.5E-6 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 VMUT_2302 29e787e4e7efdab25638bf86ffc4c5f6 405 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 2 355 9.4E-8 T 23-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 VMUT_2302 29e787e4e7efdab25638bf86ffc4c5f6 405 Gene3D G3DSA:1.10.4160.10 1 399 4.2E-32 T 23-10-2018 IPR038271 Purine-cytosine permease superfamily VMUT_0863 102bcec2bfea5c8f33b500877f816c5c 50 SUPERFAMILY SSF46785 2 42 1.04E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0863 102bcec2bfea5c8f33b500877f816c5c 50 Gene3D G3DSA:1.10.10.10 1 43 5.4E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_2140 352d87091b24c46657b3a3f17c179314 307 Gene3D G3DSA:3.40.50.1100 55 154 2.4E-66 T 23-10-2018 VMUT_2140 352d87091b24c46657b3a3f17c179314 307 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 24 290 1.2E-49 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme VMUT_2140 352d87091b24c46657b3a3f17c179314 307 SUPERFAMILY SSF53686 20 302 1.31E-64 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme VMUT_2140 352d87091b24c46657b3a3f17c179314 307 Gene3D G3DSA:3.40.50.1100 27 297 2.4E-66 T 23-10-2018 VMUT_0306 aad6a9bc732e84b3723f4609a57e9b08 179 Hamap MF_00146 dCTP deaminase [dcd]. 2 174 26.426 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 VMUT_0306 aad6a9bc732e84b3723f4609a57e9b08 179 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 4 173 2.2E-46 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 VMUT_0306 aad6a9bc732e84b3723f4609a57e9b08 179 SUPERFAMILY SSF51283 3 174 1.44E-37 T 23-10-2018 IPR036157 dUTPase-like superfamily VMUT_0306 aad6a9bc732e84b3723f4609a57e9b08 179 Gene3D G3DSA:2.70.40.10 2 177 1.6E-38 T 23-10-2018 IPR036157 dUTPase-like superfamily VMUT_0306 aad6a9bc732e84b3723f4609a57e9b08 179 Pfam PF00692 dUTPase 73 153 6.4E-13 T 23-10-2018 IPR029054 dUTPase-like VMUT_1937 8ef7ce106aea985d972dfd5aba9a234c 402 SUPERFAMILY SSF53271 185 395 2.84E-40 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like VMUT_1937 8ef7ce106aea985d972dfd5aba9a234c 402 Gene3D G3DSA:3.60.20.10 104 395 9.2E-51 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VMUT_1937 8ef7ce106aea985d972dfd5aba9a234c 402 Pfam PF00156 Phosphoribosyl transferase domain 211 325 1.3E-9 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 VMUT_1937 8ef7ce106aea985d972dfd5aba9a234c 402 Gene3D G3DSA:3.40.50.2020 210 377 9.2E-51 T 23-10-2018 VMUT_2026 b1a7be5c907e7e417f00ed700d7e92f2 102 Gene3D G3DSA:3.30.460.10 22 102 3.2E-19 T 23-10-2018 VMUT_2026 b1a7be5c907e7e417f00ed700d7e92f2 102 Pfam PF01909 Nucleotidyltransferase domain 26 69 4.1E-10 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 VMUT_2026 b1a7be5c907e7e417f00ed700d7e92f2 102 SUPERFAMILY SSF81301 25 96 3.52E-15 T 23-10-2018 VMUT_2273 8fc8986c1b35a74fe1f7e31810eeeeb4 136 Gene3D G3DSA:3.50.50.60 34 74 6.0E-17 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_2273 8fc8986c1b35a74fe1f7e31810eeeeb4 136 Gene3D G3DSA:3.30.9.10 3 33 6.0E-17 T 23-10-2018 VMUT_2273 8fc8986c1b35a74fe1f7e31810eeeeb4 136 Pfam PF01266 FAD dependent oxidoreductase 3 66 1.7E-7 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VMUT_0824 4c4d4dcc461da74bc4b42cdb3356fea9 222 SUPERFAMILY SSF53850 59 210 5.43E-6 T 23-10-2018 VMUT_0824 4c4d4dcc461da74bc4b42cdb3356fea9 222 Pfam PF12916 Protein of unknown function (DUF3834) 1 200 3.8E-70 T 23-10-2018 IPR024533 Protein of unknown function DUF3834 VMUT_0824 4c4d4dcc461da74bc4b42cdb3356fea9 222 Gene3D G3DSA:3.40.190.200 2 190 3.6E-34 T 23-10-2018 VMUT_1105 2c0ad783fb3489825b8b0bf8eaea6588 195 Pfam PF07760 Protein of unknown function (DUF1616) 80 185 6.4E-33 T 23-10-2018 IPR011674 Domain of unknown function DUF1616 VMUT_1781 9ea6b44bf83edba1e5c28a5568e324c9 100 Hamap MF_00342 UPF0147 protein . 16 97 29.647 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 VMUT_1781 9ea6b44bf83edba1e5c28a5568e324c9 100 Pfam PF03685 Uncharacterised protein family (UPF0147) 17 96 1.9E-30 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 VMUT_1781 9ea6b44bf83edba1e5c28a5568e324c9 100 ProDom PD029943 UPF0147 ARCHAEAL PF0239 ST0460.1 MM1385 CYTOSOLIC SACI_0891 TV0625 APES069 TA0600 20 97 2.0E-17 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 VMUT_1781 9ea6b44bf83edba1e5c28a5568e324c9 100 Gene3D G3DSA:1.20.1440.50 15 98 9.0E-27 T 23-10-2018 IPR023130 Ta0600-like superfamily VMUT_1781 9ea6b44bf83edba1e5c28a5568e324c9 100 SUPERFAMILY SSF158436 15 98 2.62E-28 T 23-10-2018 VMUT_1929 9c511346ef46b74bd79e2dda42004f72 283 Gene3D G3DSA:3.30.230.10 48 141 9.4E-7 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup VMUT_1929 9c511346ef46b74bd79e2dda42004f72 283 Pfam PF00288 GHMP kinases N terminal domain 73 135 3.2E-8 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 VMUT_1929 9c511346ef46b74bd79e2dda42004f72 283 SUPERFAMILY SSF54211 8 140 3.04E-9 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VMUT_1929 9c511346ef46b74bd79e2dda42004f72 283 PIRSF PIRSF016896 5 266 1.6E-62 T 23-10-2018 IPR012043 Pantoate kinase KEGG: 00770+2.7.1.169|MetaCyc: PWY-6654 VMUT_0498 ffeb63892c43bbc59552f9eaaad32721 250 Pfam PF02665 Nitrate reductase gamma subunit 60 245 5.1E-27 T 23-10-2018 IPR023234 NarG-like domain VMUT_0498 ffeb63892c43bbc59552f9eaaad32721 250 Gene3D G3DSA:1.20.950.20 56 238 3.1E-28 T 23-10-2018 VMUT_0498 ffeb63892c43bbc59552f9eaaad32721 250 SUPERFAMILY SSF103501 2 235 1.31E-30 T 23-10-2018 IPR036197 NarG-like superfamily VMUT_1419 86ccd57f38c04def21fdc2723ce6fc5b 215 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 5 207 1.4E-24 T 23-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 VMUT_1419 86ccd57f38c04def21fdc2723ce6fc5b 215 SUPERFAMILY SSF51366 3 211 1.15E-32 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 VMUT_1419 86ccd57f38c04def21fdc2723ce6fc5b 215 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 2 213 25.348 T 23-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 VMUT_1419 86ccd57f38c04def21fdc2723ce6fc5b 215 Gene3D G3DSA:3.20.20.70 1 214 3.1E-36 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_1999 312ff5fd0a20634afa29f70a89d6ed9a 175 Gene3D G3DSA:1.20.120.20 5 174 5.5E-7 T 23-10-2018 VMUT_0074 fc6ab98771ea5b4b06769ace3a6061ab 152 Gene3D G3DSA:1.20.5.340 15 96 3.5E-9 T 23-10-2018 VMUT_0253 c4a405af3d5f61ad385b5c045504ca65 134 Pfam PF03966 Trm112p-like protein 1 86 4.1E-13 T 23-10-2018 IPR005651 Trm112-like VMUT_0253 c4a405af3d5f61ad385b5c045504ca65 134 SUPERFAMILY SSF158997 59 102 1.57E-11 T 23-10-2018 VMUT_1472 6ad995b8cd1c259018813f9803bd176e 576 SUPERFAMILY SSF52540 145 570 1.35E-32 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1472 6ad995b8cd1c259018813f9803bd176e 576 Gene3D G3DSA:3.40.50.300 380 575 3.3E-20 T 23-10-2018 VMUT_1472 6ad995b8cd1c259018813f9803bd176e 576 Pfam PF01935 Domain of unknown function DUF87 157 336 5.5E-9 T 23-10-2018 IPR002789 Helicase HerA, central domain VMUT_1472 6ad995b8cd1c259018813f9803bd176e 576 Pfam PF05872 Bacterial protein of unknown function (DUF853) 461 517 8.3E-5 T 23-10-2018 IPR033186 Helicase HerA-like C-terminal VMUT_1472 6ad995b8cd1c259018813f9803bd176e 576 Gene3D G3DSA:3.40.50.300 129 262 1.8E-9 T 23-10-2018 VMUT_1472 6ad995b8cd1c259018813f9803bd176e 576 SMART SM00382 166 528 3.5E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_0577 68de408894e691d23e8abb8a9af0f7ea 129 Pfam PF01989 Protein of unknown function DUF126 25 99 8.1E-25 T 23-10-2018 IPR002840 Aconitase X swivel domain, putative VMUT_0577 68de408894e691d23e8abb8a9af0f7ea 129 Gene3D G3DSA:3.50.30.10 1 129 1.3E-31 T 23-10-2018 VMUT_0577 68de408894e691d23e8abb8a9af0f7ea 129 PIRSF PIRSF004966 1 129 4.0E-35 T 23-10-2018 IPR012016 Aconitase X subunit 2, putative VMUT_0577 68de408894e691d23e8abb8a9af0f7ea 129 SUPERFAMILY SSF52016 9 126 1.18E-31 T 23-10-2018 VMUT_1035 80dc331b4ad7c2a27e9d1ea0eaec9f14 319 SMART SM00382 40 172 2.9E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_1035 80dc331b4ad7c2a27e9d1ea0eaec9f14 319 SUPERFAMILY SSF52540 10 291 1.65E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1035 80dc331b4ad7c2a27e9d1ea0eaec9f14 319 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 43 173 1.5E-32 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 VMUT_1035 80dc331b4ad7c2a27e9d1ea0eaec9f14 319 PIRSF PIRSF002849 3 319 8.1E-82 T 23-10-2018 VMUT_1035 80dc331b4ad7c2a27e9d1ea0eaec9f14 319 Gene3D G3DSA:3.40.50.300 10 207 1.7E-39 T 23-10-2018 VMUT_1035 80dc331b4ad7c2a27e9d1ea0eaec9f14 319 Gene3D G3DSA:1.10.8.300 209 315 3.6E-26 T 23-10-2018 VMUT_1122 921977d057abb71e604e44047c13851b 408 Pfam PF00534 Glycosyl transferases group 1 221 386 7.6E-29 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 VMUT_1122 921977d057abb71e604e44047c13851b 408 Gene3D G3DSA:3.40.50.2000 1 214 2.8E-5 T 23-10-2018 VMUT_1122 921977d057abb71e604e44047c13851b 408 Gene3D G3DSA:3.40.50.2000 215 389 2.2E-37 T 23-10-2018 VMUT_1122 921977d057abb71e604e44047c13851b 408 SUPERFAMILY SSF53756 7 398 1.26E-51 T 23-10-2018 VMUT_1459 9f914c5f1c14494b6e907570e6aa30ac 462 SUPERFAMILY SSF81340 10 444 1.96E-74 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 VMUT_1459 9f914c5f1c14494b6e907570e6aa30ac 462 Gene3D G3DSA:1.10.3080.10 23 461 3.7E-66 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 VMUT_1459 9f914c5f1c14494b6e907570e6aa30ac 462 PRINTS PR00762 Chloride channel signature 186 205 1.4E-14 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 VMUT_1459 9f914c5f1c14494b6e907570e6aa30ac 462 PRINTS PR00762 Chloride channel signature 411 430 1.4E-14 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 VMUT_1459 9f914c5f1c14494b6e907570e6aa30ac 462 PRINTS PR00762 Chloride channel signature 393 409 1.4E-14 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 VMUT_1459 9f914c5f1c14494b6e907570e6aa30ac 462 PRINTS PR00762 Chloride channel signature 135 154 1.4E-14 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 VMUT_1459 9f914c5f1c14494b6e907570e6aa30ac 462 PRINTS PR00762 Chloride channel signature 358 378 1.4E-14 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 VMUT_1459 9f914c5f1c14494b6e907570e6aa30ac 462 Pfam PF00654 Voltage gated chloride channel 92 442 1.6E-66 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 VMUT_1200 3b34103be108a099375de7315b6d3248 424 Gene3D G3DSA:1.20.1250.20 14 207 3.0E-17 T 23-10-2018 VMUT_1200 3b34103be108a099375de7315b6d3248 424 SUPERFAMILY SSF103473 9 419 2.09E-38 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_1200 3b34103be108a099375de7315b6d3248 424 Pfam PF07690 Major Facilitator Superfamily 21 268 1.7E-17 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_1200 3b34103be108a099375de7315b6d3248 424 Gene3D G3DSA:1.20.1250.20 224 419 7.0E-8 T 23-10-2018 VMUT_0307 67a56f5ed8ff81787a1dc59a146b92c5 393 SUPERFAMILY SSF53743 106 256 1.03E-19 T 23-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 VMUT_1757 5334a20b2acdc7339261ac1980866477 438 SUPERFAMILY SSF52540 74 360 3.4E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1757 5334a20b2acdc7339261ac1980866477 438 Gene3D G3DSA:3.40.50.300 192 437 4.2E-66 T 23-10-2018 VMUT_1757 5334a20b2acdc7339261ac1980866477 438 Gene3D G3DSA:3.30.450.380 4 189 6.6E-31 T 23-10-2018 VMUT_1757 5334a20b2acdc7339261ac1980866477 438 Pfam PF00437 Type II/IV secretion system protein 140 349 3.7E-41 T 23-10-2018 IPR001482 Type II/IV secretion system protein VMUT_0547 748f871256237ef1355ef1c317312780 377 Gene3D G3DSA:1.20.1250.20 12 373 5.2E-13 T 23-10-2018 VMUT_0547 748f871256237ef1355ef1c317312780 377 SUPERFAMILY SSF103473 16 368 1.31E-15 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_1903 a32675a67a54a78dbfa41b2f3b00f8c5 285 SUPERFAMILY SSF52540 19 130 6.98E-5 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1903 a32675a67a54a78dbfa41b2f3b00f8c5 285 SUPERFAMILY SSF52540 17 240 4.6E-9 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0191 4017129cc1d2e59d256daeeb17533291 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 262 278 2.8E-7 T 23-10-2018 VMUT_0191 4017129cc1d2e59d256daeeb17533291 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 2.8E-7 T 23-10-2018 VMUT_0191 4017129cc1d2e59d256daeeb17533291 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 247 262 2.8E-7 T 23-10-2018 VMUT_0191 4017129cc1d2e59d256daeeb17533291 392 SUPERFAMILY SSF51905 4 324 3.74E-28 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0191 4017129cc1d2e59d256daeeb17533291 392 Gene3D G3DSA:3.50.50.60 2 379 1.2E-41 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_0692 63afdfab1567b5bb1df641a4cacea2fa 93 Pfam PF01998 Protein of unknown function DUF131 29 86 9.9E-22 T 23-10-2018 IPR002849 Protein of unknown function DUF131 VMUT_0247 41ec175ea96a4722de01e3796c17567d 204 SUPERFAMILY SSF74784 5 181 1.24E-36 T 23-10-2018 IPR036081 Translin superfamily GO:0043565 Reactome: R-HSA-426486 VMUT_0247 41ec175ea96a4722de01e3796c17567d 204 Pfam PF01997 Translin family 17 173 5.7E-14 T 23-10-2018 IPR002848 Translin family GO:0043565 Reactome: R-HSA-426486 VMUT_0247 41ec175ea96a4722de01e3796c17567d 204 Gene3D G3DSA:1.20.58.2140 1 184 1.4E-56 T 23-10-2018 VMUT_0114 3b96b951d9d1edd8afe4e0f91858b0a1 156 Gene3D G3DSA:3.30.530.20 3 154 7.1E-21 T 23-10-2018 IPR023393 START-like domain superfamily VMUT_0114 3b96b951d9d1edd8afe4e0f91858b0a1 156 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 9 150 5.5E-16 T 23-10-2018 IPR010419 Carbon monoxide dehydrogenase subunit G VMUT_0114 3b96b951d9d1edd8afe4e0f91858b0a1 156 SUPERFAMILY SSF55961 7 149 1.33E-16 T 23-10-2018 VMUT_0421 c67974b2ef8f59e53f2a5c9b48037809 88 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 47 1.9E-8 T 23-10-2018 VMUT_0421 c67974b2ef8f59e53f2a5c9b48037809 88 SUPERFAMILY SSF46785 4 83 8.69E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_0421 c67974b2ef8f59e53f2a5c9b48037809 88 Gene3D G3DSA:1.10.10.10 1 62 1.1E-26 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_1968 999fea3dd771f27390b665e38a75840f 760 SUPERFAMILY SSF48208 320 653 5.35E-26 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 VMUT_1968 999fea3dd771f27390b665e38a75840f 760 Gene3D G3DSA:1.50.10.10 344 666 3.5E-18 T 23-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 VMUT_0676 df020eaacc57290ba0f31217c2dabc28 361 Pfam PF07690 Major Facilitator Superfamily 11 309 9.7E-25 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_0676 df020eaacc57290ba0f31217c2dabc28 361 Gene3D G3DSA:1.20.1250.20 187 361 6.4E-6 T 23-10-2018 VMUT_0676 df020eaacc57290ba0f31217c2dabc28 361 Gene3D G3DSA:1.20.1250.20 1 180 2.5E-21 T 23-10-2018 VMUT_0676 df020eaacc57290ba0f31217c2dabc28 361 SUPERFAMILY SSF103473 3 360 6.02E-31 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_0435 281fe9ef1264387ad9f0ff33bf0bbc3a 278 Gene3D G3DSA:3.40.1010.10 2 118 1.6E-25 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 VMUT_0435 281fe9ef1264387ad9f0ff33bf0bbc3a 278 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 7 226 2.7E-26 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 VMUT_0435 281fe9ef1264387ad9f0ff33bf0bbc3a 278 Gene3D G3DSA:3.30.950.10 119 267 3.1E-34 T 23-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 VMUT_0435 281fe9ef1264387ad9f0ff33bf0bbc3a 278 PIRSF PIRSF036432 7 262 2.5E-67 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 VMUT_0435 281fe9ef1264387ad9f0ff33bf0bbc3a 278 Hamap MF_01084 Diphthine synthase [dphB]. 7 258 27.622 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 VMUT_0435 281fe9ef1264387ad9f0ff33bf0bbc3a 278 SUPERFAMILY SSF53790 7 254 2.49E-43 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 VMUT_0435 281fe9ef1264387ad9f0ff33bf0bbc3a 278 TIGRFAM TIGR00522 dph5: diphthine synthase 8 257 9.2E-49 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 VMUT_0907 3b9ca895c00e41891d356708e86f1d02 172 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 2 140 18.231 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 VMUT_0907 3b9ca895c00e41891d356708e86f1d02 172 Pfam PF03946 Ribosomal protein L11, N-terminal domain 6 62 2.7E-9 T 23-10-2018 IPR020784 Ribosomal protein L11, N-terminal VMUT_0907 3b9ca895c00e41891d356708e86f1d02 172 Gene3D G3DSA:2.10.260.30 2 68 8.4E-9 T 23-10-2018 VMUT_0907 3b9ca895c00e41891d356708e86f1d02 172 SMART SM00649 6 139 4.2E-22 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 VMUT_0907 3b9ca895c00e41891d356708e86f1d02 172 Gene3D G3DSA:1.10.10.250 74 164 4.5E-26 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily VMUT_0907 3b9ca895c00e41891d356708e86f1d02 172 SUPERFAMILY SSF46906 72 143 9.94E-15 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily VMUT_0907 3b9ca895c00e41891d356708e86f1d02 172 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 138 5.6E-14 T 23-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 VMUT_0907 3b9ca895c00e41891d356708e86f1d02 172 SUPERFAMILY SSF54747 3 83 1.16E-7 T 23-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily VMUT_0487 f45dcddeb88f567818fe542d94762c0d 458 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 7 442 1.8E-120 T 23-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 VMUT_0487 f45dcddeb88f567818fe542d94762c0d 458 Gene3D G3DSA:3.40.50.300 48 195 1.6E-11 T 23-10-2018 VMUT_0487 f45dcddeb88f567818fe542d94762c0d 458 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 8 188 6.7E-14 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain VMUT_0487 f45dcddeb88f567818fe542d94762c0d 458 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 253 439 2.5E-28 T 23-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 VMUT_0487 f45dcddeb88f567818fe542d94762c0d 458 Gene3D G3DSA:3.40.50.880 247 435 6.0E-8 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like VMUT_0487 f45dcddeb88f567818fe542d94762c0d 458 SUPERFAMILY SSF52317 249 452 2.21E-27 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like VMUT_0487 f45dcddeb88f567818fe542d94762c0d 458 SUPERFAMILY SSF52540 6 188 8.18E-28 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_2167 592becd35c1da8e9d70c70000fa2d5c9 449 SUPERFAMILY SSF53743 161 305 2.09E-13 T 23-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 VMUT_0891 0ca385a20b5af6419a3e2d92dc3093a1 274 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 5 98 4.2E-18 T 23-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 VMUT_0891 0ca385a20b5af6419a3e2d92dc3093a1 274 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 115 210 7.3E-17 T 23-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 VMUT_0891 0ca385a20b5af6419a3e2d92dc3093a1 274 Gene3D G3DSA:3.20.20.60 1 274 5.2E-87 T 23-10-2018 VMUT_0891 0ca385a20b5af6419a3e2d92dc3093a1 274 PIRSF PIRSF015582 1 274 6.8E-90 T 23-10-2018 IPR011206 Citrate lyase beta subunit-like VMUT_0891 0ca385a20b5af6419a3e2d92dc3093a1 274 SUPERFAMILY SSF51621 2 222 7.68E-57 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 VMUT_0439 1e0f858c08c08a35f010f7c9ea54c8dd 249 Gene3D G3DSA:3.50.30.50 14 245 9.7E-57 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 VMUT_0439 1e0f858c08c08a35f010f7c9ea54c8dd 249 SUPERFAMILY SSF102198 19 245 2.22E-52 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 VMUT_0439 1e0f858c08c08a35f010f7c9ea54c8dd 249 Pfam PF04199 Putative cyclase 20 170 2.7E-29 T 23-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 VMUT_1712 1ea40cdb0e27c711483ee094ae92e6db 160 Pfam PF05942 Archaeal PaREP1/PaREP8 family 35 147 3.0E-36 T 23-10-2018 IPR010268 Archaeal PaREP1 VMUT_1712 1ea40cdb0e27c711483ee094ae92e6db 160 Gene3D G3DSA:1.20.120.330 36 157 2.3E-38 T 23-10-2018 VMUT_0574 d85247c0473c743f6ac02b624355c2e3 135 Pfam PF02416 mttA/Hcf106 family 19 58 5.0E-13 T 23-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 VMUT_2248 0f390e9350f04226f052f57bf91168b1 141 Gene3D G3DSA:3.30.530.20 9 136 3.4E-10 T 23-10-2018 IPR023393 START-like domain superfamily VMUT_2248 0f390e9350f04226f052f57bf91168b1 141 SUPERFAMILY SSF55961 7 93 4.19E-12 T 23-10-2018 VMUT_2248 0f390e9350f04226f052f57bf91168b1 141 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 18 71 1.1E-5 T 23-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 VMUT_1958 4ff124359dc08efc13e574acfdab5a1b 204 Gene3D G3DSA:3.30.70.260 2 64 4.2E-5 T 23-10-2018 VMUT_1958 4ff124359dc08efc13e574acfdab5a1b 204 SUPERFAMILY SSF55021 3 41 4.58E-6 T 23-10-2018 VMUT_1492 5ca1e561c72c137371ea449acf57ce61 358 Gene3D G3DSA:3.40.50.300 1 313 2.8E-13 T 23-10-2018 VMUT_1492 5ca1e561c72c137371ea449acf57ce61 358 SUPERFAMILY SSF52540 5 299 3.49E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1212 c7d17fbbffe30c28f5ff5d6094611d8d 124 Gene3D G3DSA:3.40.50.1010 1 122 2.1E-8 T 23-10-2018 VMUT_1212 c7d17fbbffe30c28f5ff5d6094611d8d 124 SUPERFAMILY SSF88723 7 116 8.04E-5 T 23-10-2018 IPR029060 PIN-like domain superfamily VMUT_0244 d42726fd05550e30b3b3c2fad5aa989c 240 Pfam PF00583 Acetyltransferase (GNAT) family 25 124 3.8E-15 T 23-10-2018 IPR000182 GNAT domain VMUT_0244 d42726fd05550e30b3b3c2fad5aa989c 240 SUPERFAMILY SSF55729 1 127 5.48E-26 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase VMUT_0244 d42726fd05550e30b3b3c2fad5aa989c 240 Gene3D G3DSA:3.40.630.30 1 171 4.8E-33 T 23-10-2018 VMUT_0260 177f2bbc729107f82bf0e19f74a5213b 456 SUPERFAMILY SSF55003 259 414 5.89E-35 T 23-10-2018 IPR011068 Nucleotidyltransferase, class I-like, C-terminal GO:0003723|GO:0016779|GO:0031123 VMUT_0260 177f2bbc729107f82bf0e19f74a5213b 456 Gene3D G3DSA:3.30.70.590 283 408 4.6E-7 T 23-10-2018 VMUT_0260 177f2bbc729107f82bf0e19f74a5213b 456 PIRSF PIRSF005335 1 447 5.2E-123 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 VMUT_0260 177f2bbc729107f82bf0e19f74a5213b 456 SUPERFAMILY SSF81301 3 151 1.8E-24 T 23-10-2018 VMUT_0260 177f2bbc729107f82bf0e19f74a5213b 456 Gene3D G3DSA:1.10.1410.30 9 272 4.5E-83 T 23-10-2018 VMUT_0260 177f2bbc729107f82bf0e19f74a5213b 456 Pfam PF01909 Nucleotidyltransferase domain 40 141 1.0E-9 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 VMUT_0260 177f2bbc729107f82bf0e19f74a5213b 456 SUPERFAMILY SSF81631 156 273 8.24E-33 T 23-10-2018 VMUT_0260 177f2bbc729107f82bf0e19f74a5213b 456 Gene3D G3DSA:3.30.460.10 16 154 4.5E-83 T 23-10-2018 VMUT_0260 177f2bbc729107f82bf0e19f74a5213b 456 TIGRFAM TIGR03671 cca_archaeal: CCA-adding enzyme 7 407 3.7E-124 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 VMUT_0260 177f2bbc729107f82bf0e19f74a5213b 456 Hamap MF_01264 CCA-adding enzyme [cca]. 1 456 126.498 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 VMUT_0260 177f2bbc729107f82bf0e19f74a5213b 456 Pfam PF09249 tRNA nucleotidyltransferase, second domain 158 273 8.9E-41 T 23-10-2018 IPR015329 tRNA nucleotidyltransferase, substrate binding GO:0004810|GO:0016437 VMUT_0841 ce8a6a04668382c6a993250dda146994 206 Pfam PF02517 CAAX protease self-immunity 108 194 4.8E-11 T 23-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 VMUT_1357 e601da381eeb2aeb3c9134c5fd5e9351 363 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 49 357 1.2E-100 T 23-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 VMUT_1357 e601da381eeb2aeb3c9134c5fd5e9351 363 Gene3D G3DSA:3.20.20.70 4 346 1.9E-53 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_1357 e601da381eeb2aeb3c9134c5fd5e9351 363 SUPERFAMILY SSF102114 14 321 1.57E-43 T 23-10-2018 VMUT_1357 e601da381eeb2aeb3c9134c5fd5e9351 363 Pfam PF04055 Radical SAM superfamily 57 227 1.2E-10 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_1357 e601da381eeb2aeb3c9134c5fd5e9351 363 PIRSF PIRSF004762 8 362 4.9E-99 T 23-10-2018 VMUT_0582 74707f9e126ab4d1d5c233c61d98eb10 300 Pfam PF09973 Predicted membrane protein (DUF2208) 24 287 8.6E-23 T 23-10-2018 IPR009198 Uncharacterised conserved protein UCP014484, transmembrane VMUT_0545 242b0267b728c64caa5912f75a8b0959 111 Gene3D G3DSA:2.10.260.10 20 108 7.9E-9 T 23-10-2018 VMUT_0545 242b0267b728c64caa5912f75a8b0959 111 SUPERFAMILY SSF89447 75 103 9.24E-5 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily VMUT_0190 fd0aeea0832a5f1442aa3238e16bcfe1 567 SMART SM00471 52 255 4.6E-7 T 23-10-2018 IPR003607 HD/PDEase domain VMUT_0190 fd0aeea0832a5f1442aa3238e16bcfe1 567 Pfam PF01966 HD domain 56 180 2.3E-8 T 23-10-2018 IPR006674 HD domain VMUT_0190 fd0aeea0832a5f1442aa3238e16bcfe1 567 Gene3D G3DSA:1.10.3210.10 5 401 1.3E-66 T 23-10-2018 VMUT_0190 fd0aeea0832a5f1442aa3238e16bcfe1 567 SUPERFAMILY SSF109604 4 405 2.09E-59 T 23-10-2018 VMUT_0551 c138b42a684fda5a4132e9151e956f60 310 Pfam PF02754 Cysteine-rich domain 205 290 3.1E-6 T 23-10-2018 IPR004017 Cysteine-rich domain VMUT_0992 155e3a2db415dfa39cc517e004f9293a 459 Gene3D G3DSA:3.40.50.300 5 183 1.2E-13 T 23-10-2018 VMUT_0992 155e3a2db415dfa39cc517e004f9293a 459 SUPERFAMILY SSF52540 3 299 1.97E-14 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0740 2bb19b7895be2a329dc035c42e0e2492 416 Pfam PF01566 Natural resistance-associated macrophage protein 40 390 7.6E-41 T 23-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 VMUT_1748 259275a521c1a7a02f5a66dedb0d778d 158 Pfam PF00827 Ribosomal L15 100 140 8.8E-5 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1748 259275a521c1a7a02f5a66dedb0d778d 158 Hamap MF_00499 50S ribosomal protein L13e [rpl13e]. 10 89 22.112 T 23-10-2018 IPR001380 Ribosomal protein L13e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1748 259275a521c1a7a02f5a66dedb0d778d 158 Pfam PF01294 Ribosomal protein L13e 34 85 2.7E-9 T 23-10-2018 IPR001380 Ribosomal protein L13e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_0592 42866aa9921f4c9504818bff6d9ecf35 144 SUPERFAMILY SSF52402 5 144 1.76E-40 T 23-10-2018 VMUT_0592 42866aa9921f4c9504818bff6d9ecf35 144 Pfam PF00582 Universal stress protein family 5 144 3.9E-35 T 23-10-2018 IPR006016 UspA VMUT_0592 42866aa9921f4c9504818bff6d9ecf35 144 Gene3D G3DSA:3.40.50.620 3 144 3.7E-40 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_0592 42866aa9921f4c9504818bff6d9ecf35 144 PRINTS PR01438 Universal stress protein signature 104 116 9.0E-21 T 23-10-2018 IPR006015 Universal stress protein A VMUT_0592 42866aa9921f4c9504818bff6d9ecf35 144 PRINTS PR01438 Universal stress protein signature 4 22 9.0E-21 T 23-10-2018 IPR006015 Universal stress protein A VMUT_0592 42866aa9921f4c9504818bff6d9ecf35 144 PRINTS PR01438 Universal stress protein signature 122 144 9.0E-21 T 23-10-2018 IPR006015 Universal stress protein A VMUT_1894 d4b1decece67f18cad132c6cd93daa4e 423 Pfam PF01385 Probable transposase 186 293 5.3E-31 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 VMUT_1894 d4b1decece67f18cad132c6cd93daa4e 423 Pfam PF07282 Putative transposase DNA-binding domain 309 376 9.2E-17 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal VMUT_0402 89a5156e17b3fa6edadd15f89f601046 109 Pfam PF01910 Thiamine-binding protein 17 108 4.9E-26 T 23-10-2018 IPR002767 Thiamine-binding protein VMUT_0402 89a5156e17b3fa6edadd15f89f601046 109 Gene3D G3DSA:3.30.70.930 14 109 3.0E-27 T 23-10-2018 IPR029756 MTH1187/YkoF-like VMUT_0402 89a5156e17b3fa6edadd15f89f601046 109 SUPERFAMILY SSF89957 11 108 1.22E-25 T 23-10-2018 IPR029756 MTH1187/YkoF-like VMUT_0402 89a5156e17b3fa6edadd15f89f601046 109 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 15 108 1.2E-21 T 23-10-2018 IPR002767 Thiamine-binding protein VMUT_1880 e397cb3ae9ca3f5eaf229ebd041b8d1a 389 PIRSF PIRSF001434 7 389 1.0E-127 T 23-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 VMUT_1880 e397cb3ae9ca3f5eaf229ebd041b8d1a 389 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 196 210 - T 23-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 VMUT_1880 e397cb3ae9ca3f5eaf229ebd041b8d1a 389 SUPERFAMILY SSF53383 46 387 1.65E-103 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VMUT_1880 e397cb3ae9ca3f5eaf229ebd041b8d1a 389 Gene3D G3DSA:3.90.1150.10 255 389 4.7E-50 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VMUT_1880 e397cb3ae9ca3f5eaf229ebd041b8d1a 389 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 8 386 1.5E-123 T 23-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 VMUT_1880 e397cb3ae9ca3f5eaf229ebd041b8d1a 389 Gene3D G3DSA:3.40.640.10 4 254 1.2E-73 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VMUT_0013 b60762bc0232ffb7c868009909b982b5 118 Gene3D G3DSA:2.40.70.10 4 115 3.7E-8 T 23-10-2018 IPR021109 Aspartic peptidase domain superfamily VMUT_0013 b60762bc0232ffb7c868009909b982b5 118 SUPERFAMILY SSF50630 20 101 1.31E-6 T 23-10-2018 IPR021109 Aspartic peptidase domain superfamily VMUT_2171 a8e88a99c53b669791d4d1a38e2cfd41 125 SUPERFAMILY SSF103196 9 123 2.62E-17 T 23-10-2018 VMUT_2171 a8e88a99c53b669791d4d1a38e2cfd41 125 Gene3D G3DSA:3.30.450.30 6 125 2.2E-20 T 23-10-2018 VMUT_2171 a8e88a99c53b669791d4d1a38e2cfd41 125 SMART SM00960 9 99 1.3E-4 T 23-10-2018 IPR004942 Roadblock/LAMTOR2 domain VMUT_2171 a8e88a99c53b669791d4d1a38e2cfd41 125 Pfam PF08923 Mitogen-activated protein kinase kinase 1 interacting 21 121 9.2E-5 T 23-10-2018 IPR015019 Ragulator complex protein LAMTOR3 GO:0032006 Reactome: R-HSA-1632852|Reactome: R-HSA-165159|Reactome: R-HSA-166208|Reactome: R-HSA-380972|Reactome: R-HSA-5628897|Reactome: R-HSA-5674135|Reactome: R-HSA-6798695|Reactome: R-HSA-8943724 VMUT_0169 e56c44e5f5635c56a27254c13e47f39d 283 SUPERFAMILY SSF49503 140 247 3.39E-17 T 23-10-2018 IPR008972 Cupredoxin VMUT_0169 e56c44e5f5635c56a27254c13e47f39d 283 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 154 247 2.7E-6 T 23-10-2018 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 VMUT_0169 e56c44e5f5635c56a27254c13e47f39d 283 Gene3D G3DSA:2.60.40.420 71 247 4.0E-48 T 23-10-2018 IPR008972 Cupredoxin VMUT_0169 e56c44e5f5635c56a27254c13e47f39d 283 ProSitePatterns PS00196 Type-1 copper (blue) proteins signature. 225 241 - T 23-10-2018 IPR028871 Blue (type 1) copper protein, binding site VMUT_0169 e56c44e5f5635c56a27254c13e47f39d 283 PRINTS PR00158 Rusticyanin signature 159 178 2.0E-5 T 23-10-2018 IPR001243 Rusticyanin GO:0005507|GO:0009055 VMUT_0169 e56c44e5f5635c56a27254c13e47f39d 283 PRINTS PR00158 Rusticyanin signature 138 157 2.0E-5 T 23-10-2018 IPR001243 Rusticyanin GO:0005507|GO:0009055 VMUT_0169 e56c44e5f5635c56a27254c13e47f39d 283 ProSitePatterns PS00079 Multicopper oxidases signature 1. 225 245 - T 23-10-2018 IPR033138 Multicopper oxidases, conserved site VMUT_0953 8937a9ba07ab198a7fe8acd104de84c3 646 SUPERFAMILY SSF51445 194 472 1.38E-43 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily VMUT_0953 8937a9ba07ab198a7fe8acd104de84c3 646 Gene3D G3DSA:3.20.20.70 193 477 2.0E-16 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_0953 8937a9ba07ab198a7fe8acd104de84c3 646 Pfam PF05691 Raffinose synthase or seed imbibition protein Sip1 315 517 4.2E-27 T 23-10-2018 IPR008811 Glycosyl hydrolases 36 VMUT_0953 8937a9ba07ab198a7fe8acd104de84c3 646 Pfam PF05691 Raffinose synthase or seed imbibition protein Sip1 162 247 1.5E-15 T 23-10-2018 IPR008811 Glycosyl hydrolases 36 VMUT_0517 03916320aa0c5e32d86c2db4239f651c 64 SUPERFAMILY SSF55826 4 61 1.29E-9 T 23-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 VMUT_0517 03916320aa0c5e32d86c2db4239f651c 64 Pfam PF04073 Aminoacyl-tRNA editing domain 4 61 2.0E-8 T 23-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 VMUT_0517 03916320aa0c5e32d86c2db4239f651c 64 Gene3D G3DSA:3.90.960.10 1 63 2.2E-10 T 23-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 VMUT_2240 5c7edbfa9a6c8bd5314b36daf1e21e7f 175 Pfam PF01402 Ribbon-helix-helix protein, copG family 28 63 6.5E-5 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 VMUT_0350 f307351257b3eb7d25005d38f8ab9aec 317 Gene3D G3DSA:3.40.50.970 91 316 4.0E-66 T 23-10-2018 VMUT_0350 f307351257b3eb7d25005d38f8ab9aec 317 SUPERFAMILY SSF52518 15 313 6.87E-79 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold VMUT_0350 f307351257b3eb7d25005d38f8ab9aec 317 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 52 221 3.7E-24 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 VMUT_1319 b9aa6204b6a38bd680d962c35c079f20 279 Pfam PF01925 Sulfite exporter TauE/SafE 14 270 3.2E-48 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 VMUT_2042 1d0697e3b3d342dad01736dad627ea01 93 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 9 90 6.0E-32 T 23-10-2018 VMUT_2042 1d0697e3b3d342dad01736dad627ea01 93 TIGRFAM TIGR00285 TIGR00285: DNA-binding protein Alba 6 91 2.9E-26 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 VMUT_2042 1d0697e3b3d342dad01736dad627ea01 93 Pfam PF01918 Alba 7 67 9.5E-13 T 23-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 VMUT_2042 1d0697e3b3d342dad01736dad627ea01 93 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 1 92 23.37 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 VMUT_2042 1d0697e3b3d342dad01736dad627ea01 93 SUPERFAMILY SSF82704 7 92 3.66E-20 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 VMUT_2042 1d0697e3b3d342dad01736dad627ea01 93 Gene3D G3DSA:3.30.110.20 3 92 4.0E-26 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 VMUT_2042 1d0697e3b3d342dad01736dad627ea01 93 PIRSF PIRSF028732 2 93 1.5E-30 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 VMUT_1336 95da2b2202a839d2160449552c058656 240 SMART SM00863 192 235 1.7E-10 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 VMUT_1336 95da2b2202a839d2160449552c058656 240 Gene3D G3DSA:2.40.30.130 1 88 8.7E-23 T 23-10-2018 VMUT_1336 95da2b2202a839d2160449552c058656 240 Gene3D G3DSA:3.30.980.10 89 240 1.9E-34 T 23-10-2018 VMUT_1336 95da2b2202a839d2160449552c058656 240 Pfam PF01411 tRNA synthetases class II (A) 13 92 3.7E-11 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 VMUT_1336 95da2b2202a839d2160449552c058656 240 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 193 235 9.3E-11 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 VMUT_1336 95da2b2202a839d2160449552c058656 240 SUPERFAMILY SSF50447 1 88 3.88E-15 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VMUT_1336 95da2b2202a839d2160449552c058656 240 SUPERFAMILY SSF55186 92 238 2.88E-33 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 VMUT_1428 f3f5786d5601d5b866f288979eb372d0 230 Gene3D G3DSA:3.20.20.70 25 223 1.4E-17 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VMUT_1428 f3f5786d5601d5b866f288979eb372d0 230 Pfam PF01487 Type I 3-dehydroquinase 31 211 2.3E-11 T 23-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 VMUT_1428 f3f5786d5601d5b866f288979eb372d0 230 SUPERFAMILY SSF51569 26 216 5.13E-22 T 23-10-2018 VMUT_2068 140f46dc61932544b6329dfe556faffc 110 Gene3D G3DSA:3.40.1260.10 1 110 2.7E-12 T 23-10-2018 IPR027396 DsrEFH-like VMUT_2068 140f46dc61932544b6329dfe556faffc 110 SUPERFAMILY SSF75169 1 110 8.24E-6 T 23-10-2018 IPR027396 DsrEFH-like VMUT_1986 342b91837272cae9ee94d56535a9bc6d 212 Pfam PF03070 TENA/THI-4/PQQC family 14 205 2.7E-29 T 23-10-2018 IPR004305 Thiaminase-2/PQQC VMUT_1986 342b91837272cae9ee94d56535a9bc6d 212 SUPERFAMILY SSF48613 3 203 4.9E-50 T 23-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 VMUT_1986 342b91837272cae9ee94d56535a9bc6d 212 Gene3D G3DSA:1.20.910.10 1 211 4.0E-55 T 23-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 VMUT_2291 d11e9bd6c3e6fc9f25b9b3355e400d70 289 PRINTS PR01874 DNA repair protein radA signature 58 75 1.9E-7 T 23-10-2018 VMUT_2291 d11e9bd6c3e6fc9f25b9b3355e400d70 289 PRINTS PR01874 DNA repair protein radA signature 17 45 1.9E-7 T 23-10-2018 VMUT_2291 d11e9bd6c3e6fc9f25b9b3355e400d70 289 Gene3D G3DSA:3.40.50.300 1 269 2.6E-40 T 23-10-2018 VMUT_2291 d11e9bd6c3e6fc9f25b9b3355e400d70 289 Pfam PF06745 KaiC 10 268 1.6E-28 T 23-10-2018 IPR014774 KaiC-like domain VMUT_2291 d11e9bd6c3e6fc9f25b9b3355e400d70 289 SUPERFAMILY SSF52540 3 268 2.07E-27 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1928 3437ffddda39fe15fb577bef105d7f3b 269 Pfam PF02006 Phosphopantothenate/pantothenate synthetase 72 249 1.9E-77 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase VMUT_1928 3437ffddda39fe15fb577bef105d7f3b 269 PIRSF PIRSF004853 7 261 3.2E-121 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase VMUT_1928 3437ffddda39fe15fb577bef105d7f3b 269 ProDom PD016827 ARCHAEA ST0532 APE1937 VNG0250C MM2281 PAE3406 AF0927 UNCHARACTERIZED C3_0043 MJ0209 72 257 7.0E-65 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase VMUT_1928 3437ffddda39fe15fb577bef105d7f3b 269 Gene3D G3DSA:3.40.50.12640 8 267 1.8E-105 T 23-10-2018 IPR038138 Phosphopantoate/pantothenate synthetase superfamily VMUT_2317 971e9ae88e631b65ceaeb5bcd5558283 260 Gene3D G3DSA:3.40.50.300 8 189 1.9E-7 T 23-10-2018 VMUT_2317 971e9ae88e631b65ceaeb5bcd5558283 260 SUPERFAMILY SSF52540 22 215 2.04E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_2237 98a25bfcb597df44c65eac624dfbf334 475 SUPERFAMILY SSF50475 4 308 7.06E-81 T 23-10-2018 VMUT_2237 98a25bfcb597df44c65eac624dfbf334 475 SUPERFAMILY SSF143968 323 468 3.66E-43 T 23-10-2018 VMUT_2237 98a25bfcb597df44c65eac624dfbf334 475 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 438 3.9E-99 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 VMUT_2237 98a25bfcb597df44c65eac624dfbf334 475 Gene3D G3DSA:3.40.1670.10 325 437 2.6E-35 T 23-10-2018 VMUT_2237 98a25bfcb597df44c65eac624dfbf334 475 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 413 7.2E-107 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 VMUT_0623 51d8adc6a3b40600962ce51cbf5757f0 407 Pfam PF07690 Major Facilitator Superfamily 27 264 3.6E-17 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_0623 51d8adc6a3b40600962ce51cbf5757f0 407 SUPERFAMILY SSF103473 22 403 2.22E-43 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_0623 51d8adc6a3b40600962ce51cbf5757f0 407 Gene3D G3DSA:1.20.1250.20 21 403 2.1E-38 T 23-10-2018 VMUT_0474 0bd79e2e5d9e3150d4d980b2b1429d14 136 Pfam PF05942 Archaeal PaREP1/PaREP8 family 8 122 1.2E-7 T 23-10-2018 IPR010268 Archaeal PaREP1 VMUT_0474 0bd79e2e5d9e3150d4d980b2b1429d14 136 Gene3D G3DSA:1.20.120.330 4 134 2.9E-5 T 23-10-2018 VMUT_1021 c741deed7e11d7a3ea695eb7ba227eac 611 Gene3D G3DSA:3.30.420.10 403 607 1.3E-10 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VMUT_1021 c741deed7e11d7a3ea695eb7ba227eac 611 SUPERFAMILY SSF53098 237 604 5.88E-18 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily VMUT_0399 fab1822cac58360617b656697094f5bc 91 SUPERFAMILY SSF54862 20 89 7.44E-25 T 23-10-2018 VMUT_0399 fab1822cac58360617b656697094f5bc 91 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 14 89 1.4E-35 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 VMUT_0399 fab1822cac58360617b656697094f5bc 91 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 68 79 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VMUT_0399 fab1822cac58360617b656697094f5bc 91 Gene3D G3DSA:3.30.70.20 3 91 8.0E-18 T 23-10-2018 VMUT_0399 fab1822cac58360617b656697094f5bc 91 Pfam PF14697 4Fe-4S dicluster domain 32 85 5.8E-11 T 23-10-2018 VMUT_1370 2a115aad3ba4e9d7500ca83cd3b123db 155 Gene3D G3DSA:3.30.1050.10 8 149 3.5E-39 T 23-10-2018 IPR036527 SCP2 sterol-binding domain superfamily VMUT_1370 2a115aad3ba4e9d7500ca83cd3b123db 155 SUPERFAMILY SSF55718 6 153 2.59E-26 T 23-10-2018 IPR036527 SCP2 sterol-binding domain superfamily VMUT_1915 ec4c29973602b8b8d85c9e12f2a75f03 186 Pfam PF09335 SNARE associated Golgi protein 10 135 1.5E-19 T 23-10-2018 IPR032816 SNARE associated Golgi protein VMUT_0161 fef14602beebb05fcfdf51abdbeee36c 277 SUPERFAMILY SSF103481 37 136 9.81E-11 T 23-10-2018 VMUT_0161 fef14602beebb05fcfdf51abdbeee36c 277 SUPERFAMILY SSF103481 176 276 1.27E-8 T 23-10-2018 VMUT_0161 fef14602beebb05fcfdf51abdbeee36c 277 Pfam PF00892 EamA-like transporter family 140 276 9.8E-14 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VMUT_0161 fef14602beebb05fcfdf51abdbeee36c 277 Pfam PF00892 EamA-like transporter family 8 130 8.9E-15 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VMUT_1177 a501d5847e9e57117d08dcc1d8ee5824 443 SUPERFAMILY SSF53383 21 437 1.97E-114 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VMUT_1177 a501d5847e9e57117d08dcc1d8ee5824 443 Gene3D G3DSA:3.90.1150.10 12 432 6.5E-149 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VMUT_1177 a501d5847e9e57117d08dcc1d8ee5824 443 Pfam PF00202 Aminotransferase class-III 27 434 3.9E-96 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VMUT_1177 a501d5847e9e57117d08dcc1d8ee5824 443 Gene3D G3DSA:3.40.640.10 61 325 6.5E-149 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VMUT_1307 0e1a96eb4fa3deb3cd37fdb6c6d3a598 220 Gene3D G3DSA:1.20.58.220 1 216 1.1E-27 T 23-10-2018 IPR038078 PhoU-like domain superfamily VMUT_1307 0e1a96eb4fa3deb3cd37fdb6c6d3a598 220 Pfam PF01865 Protein of unknown function DUF47 7 213 1.3E-19 T 23-10-2018 IPR018445 Putative phosphate transport regulator VMUT_1374 a4c6ae5cb099d668fe69a23584f65f64 112 Gene3D G3DSA:3.30.1050.10 3 111 3.4E-22 T 23-10-2018 IPR036527 SCP2 sterol-binding domain superfamily VMUT_1374 a4c6ae5cb099d668fe69a23584f65f64 112 SUPERFAMILY SSF55718 9 108 4.94E-18 T 23-10-2018 IPR036527 SCP2 sterol-binding domain superfamily VMUT_1374 a4c6ae5cb099d668fe69a23584f65f64 112 Pfam PF02036 SCP-2 sterol transfer family 8 106 1.6E-11 T 23-10-2018 IPR003033 SCP2 sterol-binding domain VMUT_0581 f473f5fbf28b07748b922733abd73be8 236 SUPERFAMILY SSF56281 35 208 4.4E-6 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_0544 1cb14b6c25ad2ac8225119681dd88d8a 296 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 20 264 1.5E-30 T 23-10-2018 VMUT_0544 1cb14b6c25ad2ac8225119681dd88d8a 296 Pfam PF01040 UbiA prenyltransferase family 30 261 1.3E-30 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 VMUT_0544 1cb14b6c25ad2ac8225119681dd88d8a 296 PIRSF PIRSF005355 3 296 9.7E-65 T 23-10-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 VMUT_1729 eb57e35a5efb6b3a7b871a1a3ea73b50 181 Pfam PF01927 Mut7-C RNAse domain 19 156 3.1E-28 T 23-10-2018 IPR002782 Mut7-C RNAse domain VMUT_0211 341ac09442b23cccca8b7d5fb23ce976 212 SUPERFAMILY SSF53474 4 201 3.51E-32 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold VMUT_0211 341ac09442b23cccca8b7d5fb23ce976 212 Gene3D G3DSA:3.40.50.1820 3 206 3.8E-29 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold VMUT_0211 341ac09442b23cccca8b7d5fb23ce976 212 Pfam PF00326 Prolyl oligopeptidase family 34 203 2.1E-11 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 VMUT_0812 b0671a31bbabacc90e395fcf20ea1fb3 53 Gene3D G3DSA:2.30.30.610 4 51 6.7E-17 T 23-10-2018 IPR038647 Cren7 superfamily VMUT_0812 b0671a31bbabacc90e395fcf20ea1fb3 53 Pfam PF11520 Chromatin protein Cren7 2 49 5.3E-17 T 23-10-2018 IPR020906 Double-stranded DNA-binding Cren7 GO:0003690|GO:0005737 VMUT_0812 b0671a31bbabacc90e395fcf20ea1fb3 53 Hamap MF_01387 Chromatin protein Cren7 [creN7]. 1 53 16.202 T 23-10-2018 IPR020906 Double-stranded DNA-binding Cren7 GO:0003690|GO:0005737 VMUT_1441 ecd86bbdea4834ef43c2db746453ec6e 307 Pfam PF01925 Sulfite exporter TauE/SafE 1 251 7.8E-40 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 VMUT_0599 24bac631d3516f05610461192e395b1b 209 Pfam PF01813 ATP synthase subunit D 12 199 8.2E-30 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 VMUT_1098 b983afff715737030574ebf77c8b2059 335 Gene3D G3DSA:3.40.50.300 10 176 3.0E-5 T 23-10-2018 VMUT_1098 b983afff715737030574ebf77c8b2059 335 SUPERFAMILY SSF52540 14 245 4.97E-13 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1098 b983afff715737030574ebf77c8b2059 335 Pfam PF01637 ATPase domain predominantly from Archaea 16 226 1.4E-53 T 23-10-2018 IPR011579 ATPase domain GO:0005524 VMUT_1485 45548d9fa9d7c6b487745f2163afbd43 53 TIGRFAM TIGR02549 CRISPR_DxTHG: CRISPR-associated DxTHG motif protein 20 39 3.7E-11 T 23-10-2018 IPR013383 CRISPR-associated protein DxTHG, conserved site VMUT_1485 45548d9fa9d7c6b487745f2163afbd43 53 SUPERFAMILY SSF160980 7 50 1.57E-11 T 23-10-2018 VMUT_1485 45548d9fa9d7c6b487745f2163afbd43 53 Gene3D G3DSA:3.40.50.10640 2 53 2.6E-12 T 23-10-2018 VMUT_1485 45548d9fa9d7c6b487745f2163afbd43 53 Pfam PF09455 CRISPR-associated (Cas) DxTHG family 3 45 9.8E-9 T 23-10-2018 IPR019016 CRISPR-associated DxTHG protein VMUT_1719 475e8782f5aafa70e04ebb044cadcb0c 237 Gene3D G3DSA:3.40.50.150 38 172 5.1E-9 T 23-10-2018 VMUT_1719 475e8782f5aafa70e04ebb044cadcb0c 237 SUPERFAMILY SSF53335 34 216 2.09E-18 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_0924 cd8de80834b590b9e7f7db6ae7da7510 556 SUPERFAMILY SSF51703 11 550 4.45E-196 T 23-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 VMUT_0924 cd8de80834b590b9e7f7db6ae7da7510 556 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 32 554 1.6E-228 T 23-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 VMUT_0924 cd8de80834b590b9e7f7db6ae7da7510 556 Gene3D G3DSA:3.20.20.240 1 556 1.3E-232 T 23-10-2018 VMUT_0924 cd8de80834b590b9e7f7db6ae7da7510 556 Pfam PF01642 Methylmalonyl-CoA mutase 34 548 2.7E-208 T 23-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 VMUT_1380 546c6e1699ecf91a1b8f597ae15eadc9 126 SUPERFAMILY SSF56281 35 125 9.1E-22 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_1380 546c6e1699ecf91a1b8f597ae15eadc9 126 Gene3D G3DSA:3.60.15.10 5 125 1.4E-20 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_1380 546c6e1699ecf91a1b8f597ae15eadc9 126 Pfam PF00753 Metallo-beta-lactamase superfamily 36 118 3.5E-7 T 23-10-2018 IPR001279 Metallo-beta-lactamase VMUT_0432 60b343bdbb72eecf2445f159e823c2f4 289 Gene3D G3DSA:3.40.50.620 16 283 7.5E-85 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VMUT_0432 60b343bdbb72eecf2445f159e823c2f4 289 Pfam PF02540 NAD synthase 18 261 8.2E-81 T 23-10-2018 IPR022310 NAD/GMP synthase VMUT_0432 60b343bdbb72eecf2445f159e823c2f4 289 TIGRFAM TIGR00552 nadE: NAD+ synthetase 17 262 1.1E-79 T 23-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 VMUT_0432 60b343bdbb72eecf2445f159e823c2f4 289 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 13 264 50.482 T 23-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 VMUT_0432 60b343bdbb72eecf2445f159e823c2f4 289 SUPERFAMILY SSF52402 9 264 4.63E-77 T 23-10-2018 VMUT_2051 bc67b8849da9487266d82e529ccc018f 109 Gene3D G3DSA:3.30.70.120 1 107 1.2E-38 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal VMUT_2051 bc67b8849da9487266d82e529ccc018f 109 SUPERFAMILY SSF54913 4 107 3.41E-38 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta VMUT_2051 bc67b8849da9487266d82e529ccc018f 109 Pfam PF03091 CutA1 divalent ion tolerance protein 7 104 9.9E-36 T 23-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 VMUT_0456 0d7ed7f8930b79e21db192bf06afcf6a 474 Gene3D G3DSA:1.10.3720.10 261 464 1.2E-16 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_0456 0d7ed7f8930b79e21db192bf06afcf6a 474 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 287 472 1.3E-22 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VMUT_0456 0d7ed7f8930b79e21db192bf06afcf6a 474 SUPERFAMILY SSF161098 265 455 1.09E-19 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_0848 eb9f1ac7078c8b987d10a3438631cda0 191 Gene3D G3DSA:3.30.420.10 3 144 1.6E-38 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VMUT_0848 eb9f1ac7078c8b987d10a3438631cda0 191 SUPERFAMILY SSF53098 3 138 1.77E-25 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily VMUT_0848 eb9f1ac7078c8b987d10a3438631cda0 191 Pfam PF13456 Reverse transcriptase-like 7 134 1.2E-17 T 23-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 VMUT_0027 17dc42a9eab0d55fb6e261d193866d93 555 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 167 265 8.0E-18 T 23-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VMUT_0027 17dc42a9eab0d55fb6e261d193866d93 555 Gene3D G3DSA:1.20.140.10 277 461 1.1E-42 T 23-10-2018 VMUT_0027 17dc42a9eab0d55fb6e261d193866d93 555 SUPERFAMILY SSF56645 100 283 7.98E-33 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VMUT_0027 17dc42a9eab0d55fb6e261d193866d93 555 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 277 435 6.8E-42 T 23-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VMUT_0027 17dc42a9eab0d55fb6e261d193866d93 555 SUPERFAMILY SSF47203 276 437 1.93E-42 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VMUT_0027 17dc42a9eab0d55fb6e261d193866d93 555 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 394 413 - T 23-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 VMUT_0027 17dc42a9eab0d55fb6e261d193866d93 555 Gene3D G3DSA:2.40.110.20 126 276 1.1E-31 T 23-10-2018 VMUT_0069 5408d13bb3634dcc172f9ec1d8981a54 864 Pfam PF09852 Predicted membrane protein (DUF2079) 103 485 2.0E-27 T 23-10-2018 IPR018650 Sulfolobus virus STSV1, Orf64 VMUT_1723 26789b54182309535bb89c61fe9a8feb 183 Gene3D G3DSA:3.90.550.10 2 178 2.6E-29 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1723 26789b54182309535bb89c61fe9a8feb 183 SUPERFAMILY SSF53448 1 177 5.63E-24 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1723 26789b54182309535bb89c61fe9a8feb 183 Pfam PF12804 MobA-like NTP transferase domain 3 112 5.2E-16 T 23-10-2018 IPR025877 MobA-like NTP transferase VMUT_0176 8668cc8bb9a5f8033040d409a422e886 146 Pfam PF03692 Putative zinc- or iron-chelating domain 5 90 8.0E-11 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein VMUT_2162 1012187d65bbac833999e120c2e636fa 246 Pfam PF13531 Bacterial extracellular solute-binding protein 49 241 7.4E-8 T 23-10-2018 VMUT_2162 1012187d65bbac833999e120c2e636fa 246 SUPERFAMILY SSF53850 67 241 1.36E-8 T 23-10-2018 VMUT_0596 2df0b901a998e0ba72d2ea006a6c696b 70 Pfam PF07754 Domain of unknown function (DUF1610) 21 44 3.9E-12 T 23-10-2018 IPR011668 Domain of unknown function DUF1610 VMUT_1721 bc6f271aa5202e99cb7389f9a911d5d1 167 Pfam PF05942 Archaeal PaREP1/PaREP8 family 44 158 8.7E-35 T 23-10-2018 IPR010268 Archaeal PaREP1 VMUT_1721 bc6f271aa5202e99cb7389f9a911d5d1 167 Gene3D G3DSA:1.20.120.330 45 166 1.4E-38 T 23-10-2018 VMUT_1831 293048f04703f1124fd6f8595020b903 357 Gene3D G3DSA:3.30.930.10 31 353 4.4E-70 T 23-10-2018 VMUT_1831 293048f04703f1124fd6f8595020b903 357 SUPERFAMILY SSF55681 42 350 4.58E-61 T 23-10-2018 VMUT_1831 293048f04703f1124fd6f8595020b903 357 Pfam PF00152 tRNA synthetases class II (D, K and N) 41 350 2.2E-57 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 VMUT_0851 dd50bcee71375145ec01bb73a2ad2a27 134 Pfam PF13279 Thioesterase-like superfamily 9 123 1.5E-6 T 23-10-2018 VMUT_0851 dd50bcee71375145ec01bb73a2ad2a27 134 Gene3D G3DSA:3.10.129.10 1 133 1.8E-25 T 23-10-2018 VMUT_0851 dd50bcee71375145ec01bb73a2ad2a27 134 SUPERFAMILY SSF54637 1 129 1.45E-24 T 23-10-2018 IPR029069 HotDog domain superfamily VMUT_1299 b606b5384da39c8778d971e9e46363ea 938 SUPERFAMILY SSF82866 406 578 3.92E-18 T 23-10-2018 VMUT_1299 b606b5384da39c8778d971e9e46363ea 938 SUPERFAMILY SSF82866 695 927 2.62E-27 T 23-10-2018 VMUT_1299 b606b5384da39c8778d971e9e46363ea 938 Pfam PF03176 MMPL family 407 612 1.9E-20 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 VMUT_1299 b606b5384da39c8778d971e9e46363ea 938 Pfam PF03176 MMPL family 690 930 2.0E-46 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 VMUT_0380 b15b5cff4c41df216bd55508d1ee096c 301 Gene3D G3DSA:1.10.472.100 213 301 9.3E-6 T 23-10-2018 VMUT_0637 d48a74e9c8529c6e977b45ff542af784 278 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 70 216 2.5E-34 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 VMUT_0637 d48a74e9c8529c6e977b45ff542af784 278 SUPERFAMILY SSF52518 32 244 8.65E-73 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold VMUT_0637 d48a74e9c8529c6e977b45ff542af784 278 Gene3D G3DSA:3.40.50.970 98 245 7.0E-34 T 23-10-2018 VMUT_1382 cf3344ca9dfb620d3cf936d1ae521719 223 SUPERFAMILY SSF53335 14 209 2.43E-27 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_1382 cf3344ca9dfb620d3cf936d1ae521719 223 Pfam PF08241 Methyltransferase domain 55 146 2.2E-14 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 VMUT_1382 cf3344ca9dfb620d3cf936d1ae521719 223 Gene3D G3DSA:3.40.50.150 37 223 7.5E-30 T 23-10-2018 VMUT_1202 ffd3ad8db69de50e7804a95c1a7c25e9 396 Gene3D G3DSA:1.10.45.10 368 393 1.6E-6 T 23-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 VMUT_1202 ffd3ad8db69de50e7804a95c1a7c25e9 396 Pfam PF01565 FAD binding domain 33 170 1.0E-19 T 23-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 VMUT_1202 ffd3ad8db69de50e7804a95c1a7c25e9 396 Gene3D G3DSA:3.30.465.40 4 222 1.3E-42 T 23-10-2018 VMUT_1202 ffd3ad8db69de50e7804a95c1a7c25e9 396 SUPERFAMILY SSF56176 26 209 4.07E-31 T 23-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VMUT_1202 ffd3ad8db69de50e7804a95c1a7c25e9 396 Pfam PF02913 FAD linked oxidases, C-terminal domain 370 391 1.3E-4 T 23-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 VMUT_1202 ffd3ad8db69de50e7804a95c1a7c25e9 396 SUPERFAMILY SSF55103 241 393 1.47E-12 T 23-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 VMUT_0084 0666aff58a7fd56bafde181c2aeddbe3 346 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 344 2.5E-38 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VMUT_0084 0666aff58a7fd56bafde181c2aeddbe3 346 SUPERFAMILY SSF161098 99 332 1.96E-15 T 23-10-2018 IPR035906 MetI-like superfamily VMUT_1844 0db9df2c8b6703391dd40a3b318f04ae 317 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 315 67.245 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 VMUT_1844 0db9df2c8b6703391dd40a3b318f04ae 317 Pfam PF03186 CobD/Cbib protein 14 279 1.4E-79 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 VMUT_1844 0db9df2c8b6703391dd40a3b318f04ae 317 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 11 307 1.0E-73 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 VMUT_0775 72c4500e619477845d960e3191bcbe60 416 SUPERFAMILY SSF51338 31 411 3.2E-13 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VMUT_0775 72c4500e619477845d960e3191bcbe60 416 Pfam PF07969 Amidohydrolase family 113 376 1.0E-15 T 23-10-2018 IPR013108 Amidohydrolase 3 VMUT_0775 72c4500e619477845d960e3191bcbe60 416 Gene3D G3DSA:3.20.20.140 72 362 4.4E-125 T 23-10-2018 VMUT_0775 72c4500e619477845d960e3191bcbe60 416 Gene3D G3DSA:2.30.40.10 11 400 4.4E-125 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VMUT_0775 72c4500e619477845d960e3191bcbe60 416 TIGRFAM TIGR01224 hutI: imidazolonepropionase 32 400 1.0E-110 T 23-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 VMUT_0775 72c4500e619477845d960e3191bcbe60 416 SUPERFAMILY SSF51556 72 361 3.12E-64 T 23-10-2018 IPR032466 Metal-dependent hydrolase VMUT_2337 fffbf396afd641baa31fafebd4d3d40d 620 Pfam PF00482 Type II secretion system (T2SS), protein F 396 523 5.4E-10 T 23-10-2018 IPR018076 Type II secretion system F domain VMUT_2337 fffbf396afd641baa31fafebd4d3d40d 620 Pfam PF00482 Type II secretion system (T2SS), protein F 134 257 4.7E-6 T 23-10-2018 IPR018076 Type II secretion system F domain VMUT_2337 fffbf396afd641baa31fafebd4d3d40d 620 Gene3D G3DSA:1.20.81.30 389 503 2.4E-5 T 23-10-2018 VMUT_0364 ee57788dcbef85564bce5f5a5de5ae14 459 Pfam PF04143 Sulphur transport 75 445 2.4E-27 T 23-10-2018 IPR007272 Sulphur transport domain VMUT_0030 800945d78caa1f1309fc9f7df5d83b3c 194 Gene3D G3DSA:3.40.920.10 1 194 5.2E-36 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 VMUT_0030 800945d78caa1f1309fc9f7df5d83b3c 194 SUPERFAMILY SSF53323 3 192 8.24E-25 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 VMUT_0030 800945d78caa1f1309fc9f7df5d83b3c 194 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 189 2.3E-21 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 VMUT_0513 f99ae75cf207a9edc054a3fba1673d4d 141 Pfam PF06146 Phosphate-starvation-inducible E 59 126 1.2E-10 T 23-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like VMUT_0813 300ba35fcea86ca14044bbcd87b51bc4 333 SUPERFAMILY SSF51735 1 144 1.71E-15 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily VMUT_0813 300ba35fcea86ca14044bbcd87b51bc4 333 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 4 77 9.6E-7 T 23-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VMUT_0813 300ba35fcea86ca14044bbcd87b51bc4 333 Gene3D G3DSA:3.40.50.720 1 160 9.1E-16 T 23-10-2018 VMUT_1067 366a4264d22c8d332f7c3279ade04e3b 289 Pfam PF00535 Glycosyl transferase family 2 6 121 2.4E-13 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VMUT_1067 366a4264d22c8d332f7c3279ade04e3b 289 Gene3D G3DSA:3.90.550.10 1 209 7.6E-26 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1067 366a4264d22c8d332f7c3279ade04e3b 289 SUPERFAMILY SSF53448 1 233 9.19E-33 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1696 2a25ef4c912315ceccd0b182b74ce017 228 Gene3D G3DSA:3.90.20.10 25 93 1.5E-11 T 23-10-2018 VMUT_2084 2aee6a6e00e592818872edbabd7e1b9c 347 Pfam PF02361 Cobalt transport protein 51 308 3.6E-14 T 23-10-2018 IPR003339 ABC/ECF transporter, transmembrane component VMUT_0549 99be4b94bcc9a90254334b599945eb2c 141 SUPERFAMILY SSF100966 11 107 8.76E-22 T 23-10-2018 IPR016189 Translation initiation factor IF2/IF5, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 VMUT_0549 99be4b94bcc9a90254334b599945eb2c 141 SUPERFAMILY SSF75689 105 138 1.16E-9 T 23-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 VMUT_0549 99be4b94bcc9a90254334b599945eb2c 141 SMART SM00653 27 134 7.4E-40 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 VMUT_0549 99be4b94bcc9a90254334b599945eb2c 141 Gene3D G3DSA:3.30.70.3150 38 128 6.1E-26 T 23-10-2018 VMUT_0549 99be4b94bcc9a90254334b599945eb2c 141 Pfam PF01873 Domain found in IF2B/IF5 27 134 5.0E-30 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 VMUT_1230 27b46481b13e701a35c8379f02d63c56 654 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 4 176 6.5E-47 T 23-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 VMUT_1230 27b46481b13e701a35c8379f02d63c56 654 Pfam PF01968 Hydantoinase/oxoprolinase 195 486 2.3E-97 T 23-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 VMUT_1230 27b46481b13e701a35c8379f02d63c56 654 SUPERFAMILY SSF53067 1 480 2.36E-7 T 23-10-2018 VMUT_1030 e48196a418e2feeb3075e4b7d211ee48 215 Pfam PF03070 TENA/THI-4/PQQC family 12 212 3.3E-23 T 23-10-2018 IPR004305 Thiaminase-2/PQQC VMUT_1030 e48196a418e2feeb3075e4b7d211ee48 215 Gene3D G3DSA:1.20.910.10 5 214 1.5E-17 T 23-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 VMUT_1030 e48196a418e2feeb3075e4b7d211ee48 215 SUPERFAMILY SSF48613 5 212 1.25E-35 T 23-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 VMUT_1204 aecf2f7d8dc0150367d8353fed3b0aa4 532 Pfam PF02652 L-lactate permease 14 515 7.5E-111 T 23-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 VMUT_1204 aecf2f7d8dc0150367d8353fed3b0aa4 532 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 13 521 1.9E-110 T 23-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 VMUT_2310 b799e55f4ee7c54603e08cc4ad40fbcd 273 SUPERFAMILY SSF53807 7 245 2.08E-27 T 23-10-2018 VMUT_2310 b799e55f4ee7c54603e08cc4ad40fbcd 273 Pfam PF01497 Periplasmic binding protein 14 125 1.2E-12 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain VMUT_2310 b799e55f4ee7c54603e08cc4ad40fbcd 273 Gene3D G3DSA:3.40.50.1980 3 126 1.7E-23 T 23-10-2018 VMUT_0977 4c88d99cde7232fa15d663585a7687ff 359 Pfam PF00534 Glycosyl transferases group 1 240 331 2.0E-20 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 VMUT_0977 4c88d99cde7232fa15d663585a7687ff 359 Gene3D G3DSA:3.40.50.2000 9 194 1.3E-5 T 23-10-2018 VMUT_0977 4c88d99cde7232fa15d663585a7687ff 359 SUPERFAMILY SSF53756 13 353 1.88E-44 T 23-10-2018 VMUT_0977 4c88d99cde7232fa15d663585a7687ff 359 Gene3D G3DSA:3.40.50.2000 195 333 4.6E-23 T 23-10-2018 VMUT_2226 ea9da27581f3a3db79d24b254b5be04d 197 Gene3D G3DSA:3.40.1350.150 52 194 3.0E-19 T 23-10-2018 VMUT_2226 ea9da27581f3a3db79d24b254b5be04d 197 SUPERFAMILY SSF53032 103 187 6.8E-14 T 23-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 VMUT_2226 ea9da27581f3a3db79d24b254b5be04d 197 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 103 185 1.7E-8 T 23-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 VMUT_1170 81ef4dd7f61a74a82f69fa7351a76c70 462 Gene3D G3DSA:3.40.640.10 83 335 7.2E-134 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VMUT_1170 81ef4dd7f61a74a82f69fa7351a76c70 462 Gene3D G3DSA:3.90.1150.10 25 438 7.2E-134 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VMUT_1170 81ef4dd7f61a74a82f69fa7351a76c70 462 SUPERFAMILY SSF53383 18 445 2.97E-94 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VMUT_1170 81ef4dd7f61a74a82f69fa7351a76c70 462 Pfam PF00202 Aminotransferase class-III 46 400 9.9E-63 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VMUT_0065 058f75b5ec3cf141f236b9ab4446d7d1 87 Gene3D G3DSA:3.30.420.40 1 87 2.7E-18 T 23-10-2018 VMUT_0065 058f75b5ec3cf141f236b9ab4446d7d1 87 Pfam PF02543 Carbamoyltransferase N-terminus 11 76 7.0E-9 T 23-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 VMUT_1604 7489677062e7f9dd2b583c7dc3849ab5 92 Gene3D G3DSA:2.40.10.230 1 78 4.1E-20 T 23-10-2018 IPR038664 H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain VMUT_1604 7489677062e7f9dd2b583c7dc3849ab5 92 SUPERFAMILY SSF50447 2 75 8.83E-13 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VMUT_1604 7489677062e7f9dd2b583c7dc3849ab5 92 ProDom PD064583 RNA-BINDING GAR1 COMPONENT RNP SNORNP HOMOLOG NUCLEOLAR PROCESSING RRNA VNG1366H 2 74 1.0E-6 T 23-10-2018 IPR020321 H/ACA ribonucleoprotein complex, subunit Gar1, archaea GO:0001522|GO:0042254 VMUT_0008 3540015f4f2d3b46b2c6298db698ff19 212 Gene3D G3DSA:3.40.50.150 19 207 7.5E-24 T 23-10-2018 VMUT_0008 3540015f4f2d3b46b2c6298db698ff19 212 Pfam PF05050 Methyltransferase FkbM domain 32 157 1.5E-8 T 23-10-2018 IPR006342 Methyltransferase FkbM VMUT_0008 3540015f4f2d3b46b2c6298db698ff19 212 SUPERFAMILY SSF53335 19 197 5.96E-33 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_0008 3540015f4f2d3b46b2c6298db698ff19 212 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 30 171 1.3E-24 T 23-10-2018 IPR006342 Methyltransferase FkbM VMUT_0500 8129ed90925d0fde8a1e7005e7b44126 118 SUPERFAMILY SSF75169 7 111 4.54E-16 T 23-10-2018 IPR027396 DsrEFH-like VMUT_0500 8129ed90925d0fde8a1e7005e7b44126 118 Gene3D G3DSA:3.40.1260.10 1 117 1.6E-19 T 23-10-2018 IPR027396 DsrEFH-like VMUT_0500 8129ed90925d0fde8a1e7005e7b44126 118 Pfam PF13686 DsrE/DsrF/DrsH-like family 50 113 5.2E-10 T 23-10-2018 IPR032836 DsrE2-like family VMUT_1952 400d98e32b33cf8e308cd6a194a74d7b 276 Pfam PF00482 Type II secretion system (T2SS), protein F 101 226 2.8E-12 T 23-10-2018 IPR018076 Type II secretion system F domain VMUT_1499 4e49564bd8f68dc869adec2e99d25ff1 262 Gene3D G3DSA:3.40.50.300 1 174 1.6E-7 T 23-10-2018 VMUT_1499 4e49564bd8f68dc869adec2e99d25ff1 262 SUPERFAMILY SSF52540 1 138 5.32E-9 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1034 051f43bbf09c70a5df533ecd29e8db20 528 Pfam PF01882 Protein of unknown function DUF58 353 422 8.5E-7 T 23-10-2018 IPR002881 Domain of unknown function DUF58 VMUT_0237 e2b6063b6994207ea19379125cdac0ac 139 Gene3D G3DSA:3.30.1740.20 7 99 3.2E-27 T 23-10-2018 IPR038551 Ribosomal protein S26e superfamily VMUT_0237 e2b6063b6994207ea19379125cdac0ac 139 Pfam PF01283 Ribosomal protein S26e 7 106 7.0E-30 T 23-10-2018 IPR000892 Ribosomal protein S26e GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_0801 96a83eaeed6e6b6e87f30252774709eb 231 PRINTS PR01217 Proline rich extensin signature 20 36 8.8E-10 T 23-10-2018 VMUT_0801 96a83eaeed6e6b6e87f30252774709eb 231 PRINTS PR01217 Proline rich extensin signature 163 188 8.8E-10 T 23-10-2018 VMUT_0801 96a83eaeed6e6b6e87f30252774709eb 231 PRINTS PR01217 Proline rich extensin signature 41 53 8.8E-10 T 23-10-2018 VMUT_0801 96a83eaeed6e6b6e87f30252774709eb 231 PRINTS PR01217 Proline rich extensin signature 62 83 8.8E-10 T 23-10-2018 VMUT_1480 689f682fe36e92ed98fc1c715684b871 287 TIGRFAM TIGR01898 cas_TM1791_cmr6: CRISPR type III-B/RAMP module RAMP protein Cmr6 157 285 3.3E-19 T 23-10-2018 IPR010172 CRISPR-associated protein, TM1791 VMUT_1480 689f682fe36e92ed98fc1c715684b871 287 Pfam PF03787 RAMP superfamily 131 285 1.3E-6 T 23-10-2018 IPR005537 CRISPR type III-associated RAMP protein VMUT_1244 97b17a5639fe89e193a241827c5d6072 231 Pfam PF04967 HTH DNA binding domain 171 222 1.4E-18 T 23-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain VMUT_1123 392407599070260aea1897f0ed3b2b67 219 SUPERFAMILY SSF82861 96 181 1.57E-6 T 23-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 VMUT_0346 01bd4bf4038f71ff08db6c80391a3409 136 SUPERFAMILY SSF53146 13 98 3.66E-6 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily VMUT_0287 d0ea473d6ef020de7104b38beb1edd60 231 SUPERFAMILY SSF53271 8 190 1.57E-34 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like VMUT_0287 d0ea473d6ef020de7104b38beb1edd60 231 Pfam PF00156 Phosphoribosyl transferase domain 17 150 3.3E-16 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 VMUT_0287 d0ea473d6ef020de7104b38beb1edd60 231 Gene3D G3DSA:3.40.50.2020 4 184 1.4E-37 T 23-10-2018 VMUT_1683 c6e88e5cbf2c2c1c4837aa962785dd34 409 Pfam PF13641 Glycosyltransferase like family 2 62 284 2.2E-23 T 23-10-2018 VMUT_1683 c6e88e5cbf2c2c1c4837aa962785dd34 409 Gene3D G3DSA:3.90.550.10 51 271 2.7E-28 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1683 c6e88e5cbf2c2c1c4837aa962785dd34 409 SUPERFAMILY SSF53448 57 323 1.59E-37 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_2161 573b47e9a67cf6b647c6d2b88199fbee 109 SUPERFAMILY SSF75169 2 108 4.71E-29 T 23-10-2018 IPR027396 DsrEFH-like VMUT_2161 573b47e9a67cf6b647c6d2b88199fbee 109 Gene3D G3DSA:3.40.1260.10 2 109 4.1E-37 T 23-10-2018 IPR027396 DsrEFH-like VMUT_2161 573b47e9a67cf6b647c6d2b88199fbee 109 Pfam PF02635 DsrE/DsrF-like family 26 108 3.5E-13 T 23-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein VMUT_1904 eea43bfc11a2d75bb0d0ecbc14a30b68 218 Pfam PF01955 Adenosylcobinamide amidohydrolase 20 198 1.1E-33 T 23-10-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ VMUT_1284 7e669728996e2c146c802bf0ee16e1e4 157 Pfam PF07884 Vitamin K epoxide reductase family 12 147 1.2E-24 T 23-10-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 VMUT_1284 7e669728996e2c146c802bf0ee16e1e4 157 SMART SM00756 6 151 2.6E-21 T 23-10-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 VMUT_1284 7e669728996e2c146c802bf0ee16e1e4 157 Gene3D G3DSA:1.20.1440.130 2 155 1.8E-17 T 23-10-2018 IPR038354 VKOR domain superfamily Reactome: R-HSA-6806664 VMUT_0679 b95886aedb5e1fc43003009e04ad1d45 577 Pfam PF13193 AMP-binding enzyme C-terminal domain 480 561 5.2E-20 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VMUT_0679 b95886aedb5e1fc43003009e04ad1d45 577 Gene3D G3DSA:3.40.50.12780 19 466 1.7E-109 T 23-10-2018 VMUT_0679 b95886aedb5e1fc43003009e04ad1d45 577 Gene3D G3DSA:3.30.300.310 467 576 7.1E-31 T 23-10-2018 VMUT_0679 b95886aedb5e1fc43003009e04ad1d45 577 Pfam PF00501 AMP-binding enzyme 41 471 6.6E-88 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VMUT_0679 b95886aedb5e1fc43003009e04ad1d45 577 ProSitePatterns PS00455 Putative AMP-binding domain signature. 212 223 - T 23-10-2018 IPR020845 AMP-binding, conserved site VMUT_0679 b95886aedb5e1fc43003009e04ad1d45 577 SUPERFAMILY SSF56801 26 574 5.1E-132 T 23-10-2018 VMUT_0950 84b841d1337ab5df38d6eee603e5f16b 395 Gene3D G3DSA:3.90.550.10 32 258 7.9E-25 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0950 84b841d1337ab5df38d6eee603e5f16b 395 SUPERFAMILY SSF53448 45 311 5.88E-31 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_0950 84b841d1337ab5df38d6eee603e5f16b 395 Pfam PF00535 Glycosyl transferase family 2 53 215 2.8E-15 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VMUT_2200 43227835690d389364dcde19118fa075 519 Pfam PF01935 Domain of unknown function DUF87 151 409 1.4E-9 T 23-10-2018 IPR002789 Helicase HerA, central domain VMUT_2200 43227835690d389364dcde19118fa075 519 Gene3D G3DSA:3.40.50.300 363 507 2.1E-7 T 23-10-2018 VMUT_2200 43227835690d389364dcde19118fa075 519 Gene3D G3DSA:3.40.50.300 134 307 3.5E-8 T 23-10-2018 VMUT_2200 43227835690d389364dcde19118fa075 519 SUPERFAMILY SSF52540 147 483 6.63E-11 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1405 8f4d2b216e008fcc0c6a61597b70861c 181 Gene3D G3DSA:3.40.50.300 2 176 7.4E-48 T 23-10-2018 VMUT_1405 8f4d2b216e008fcc0c6a61597b70861c 181 Pfam PF03266 NTPase 3 169 4.2E-45 T 23-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 VMUT_1405 8f4d2b216e008fcc0c6a61597b70861c 181 Hamap MF_00796 Nucleoside-triphosphatase . 2 177 27.071 T 23-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 VMUT_1405 8f4d2b216e008fcc0c6a61597b70861c 181 SUPERFAMILY SSF52540 4 171 2.18E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_1503 6184a7e3336e9a9d22a23b597a8f808d 495 Gene3D G3DSA:3.40.50.300 221 485 6.3E-38 T 23-10-2018 VMUT_1503 6184a7e3336e9a9d22a23b597a8f808d 495 Pfam PF00437 Type II/IV secretion system protein 207 388 2.2E-17 T 23-10-2018 IPR001482 Type II/IV secretion system protein VMUT_1503 6184a7e3336e9a9d22a23b597a8f808d 495 SUPERFAMILY SSF52540 107 375 1.19E-23 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_2288 2e75ac05a83253fb472a72d170f186e6 305 SUPERFAMILY SSF103481 203 300 1.7E-9 T 23-10-2018 VMUT_2288 2e75ac05a83253fb472a72d170f186e6 305 Pfam PF00892 EamA-like transporter family 169 298 2.3E-10 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VMUT_1664 680dbe85065523504fbc61bd89cd05b7 141 SUPERFAMILY SSF49764 32 134 1.05E-21 T 23-10-2018 IPR008978 HSP20-like chaperone VMUT_1664 680dbe85065523504fbc61bd89cd05b7 141 Pfam PF00011 Hsp20/alpha crystallin family 44 139 3.3E-10 T 23-10-2018 IPR002068 Alpha crystallin/Hsp20 domain VMUT_1664 680dbe85065523504fbc61bd89cd05b7 141 Gene3D G3DSA:2.60.40.790 11 132 1.3E-21 T 23-10-2018 IPR008978 HSP20-like chaperone VMUT_1063 7dd891a8589d8374fbdb114b2a687d65 377 SUPERFAMILY SSF53756 15 365 5.84E-15 T 23-10-2018 VMUT_1063 7dd891a8589d8374fbdb114b2a687d65 377 Gene3D G3DSA:3.40.50.2000 204 359 3.2E-6 T 23-10-2018 VMUT_1063 7dd891a8589d8374fbdb114b2a687d65 377 Pfam PF13692 Glycosyl transferases group 1 205 299 1.1E-6 T 23-10-2018 VMUT_1463 b19979a5c833e58d8d6cb732be61c6a3 246 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VMUT_1463 b19979a5c833e58d8d6cb732be61c6a3 246 Pfam PF00005 ABC transporter 21 158 1.1E-22 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_1463 b19979a5c833e58d8d6cb732be61c6a3 246 Gene3D G3DSA:3.40.50.300 2 238 2.8E-52 T 23-10-2018 VMUT_1463 b19979a5c833e58d8d6cb732be61c6a3 246 SMART SM00382 29 205 1.9E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain VMUT_1463 b19979a5c833e58d8d6cb732be61c6a3 246 SUPERFAMILY SSF52540 4 219 3.81E-51 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0338 b59bceb47250fdfad53108d2a3238a74 367 SUPERFAMILY SSF53850 175 344 3.11E-18 T 23-10-2018 VMUT_0338 b59bceb47250fdfad53108d2a3238a74 367 Pfam PF13531 Bacterial extracellular solute-binding protein 57 334 6.1E-18 T 23-10-2018 VMUT_0338 b59bceb47250fdfad53108d2a3238a74 367 Gene3D G3DSA:3.40.190.10 178 303 2.7E-30 T 23-10-2018 VMUT_0338 b59bceb47250fdfad53108d2a3238a74 367 Gene3D G3DSA:3.40.190.10 304 348 2.7E-30 T 23-10-2018 VMUT_0338 b59bceb47250fdfad53108d2a3238a74 367 Gene3D G3DSA:3.40.190.10 56 115 4.7E-8 T 23-10-2018 VMUT_1415 5b6f14b75d4d4f92e5847ae757464412 118 Gene3D G3DSA:2.10.260.10 16 104 2.5E-11 T 23-10-2018 VMUT_0626 a95fd02901873d256654b7f3c0b8012d 351 SUPERFAMILY SSF52540 69 311 7.27E-32 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0626 a95fd02901873d256654b7f3c0b8012d 351 Gene3D G3DSA:3.40.50.300 65 306 3.0E-45 T 23-10-2018 VMUT_0626 a95fd02901873d256654b7f3c0b8012d 351 Pfam PF06745 KaiC 69 307 7.3E-61 T 23-10-2018 IPR014774 KaiC-like domain VMUT_2110 428f8ca58a4c941b3bbe2ab1d55f10ff 232 Gene3D G3DSA:3.50.40.10 70 194 5.2E-11 T 23-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 VMUT_2110 428f8ca58a4c941b3bbe2ab1d55f10ff 232 Pfam PF03483 B3/4 domain 64 192 8.8E-25 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 VMUT_2110 428f8ca58a4c941b3bbe2ab1d55f10ff 232 SMART SM00873 61 214 2.2E-22 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 VMUT_2110 428f8ca58a4c941b3bbe2ab1d55f10ff 232 SUPERFAMILY SSF56037 46 223 1.15E-32 T 23-10-2018 VMUT_1514 c41f107a57ed276100aab5ec4ab5c9ba 176 SUPERFAMILY SSF88697 2 154 1.24E-9 T 23-10-2018 IPR015947 PUA-like superfamily VMUT_1514 c41f107a57ed276100aab5ec4ab5c9ba 176 Pfam PF01878 EVE domain 2 152 2.4E-5 T 23-10-2018 IPR002740 EVE domain VMUT_1514 c41f107a57ed276100aab5ec4ab5c9ba 176 Gene3D G3DSA:3.10.590.10 1 154 1.8E-24 T 23-10-2018 VMUT_0946 165e4b73adc5d4a76d763c23a00fdc75 628 Gene3D G3DSA:1.20.1740.10 21 478 1.6E-58 T 23-10-2018 VMUT_0946 165e4b73adc5d4a76d763c23a00fdc75 628 Pfam PF13520 Amino acid permease 27 442 6.1E-39 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_2205 81218ce01100038d9e354372b0b8f38e 229 Gene3D G3DSA:3.60.15.10 125 226 1.4E-18 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_2205 81218ce01100038d9e354372b0b8f38e 229 SUPERFAMILY SSF56281 6 200 1.44E-25 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_2205 81218ce01100038d9e354372b0b8f38e 229 Pfam PF00753 Metallo-beta-lactamase superfamily 25 126 7.8E-13 T 23-10-2018 IPR001279 Metallo-beta-lactamase VMUT_2205 81218ce01100038d9e354372b0b8f38e 229 Gene3D G3DSA:3.60.15.10 1 100 1.2E-19 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VMUT_2282 bb065726ec340f9c14b6a84b742eaa43 94 Gene3D G3DSA:2.40.70.10 2 90 5.4E-5 T 23-10-2018 IPR021109 Aspartic peptidase domain superfamily VMUT_2282 bb065726ec340f9c14b6a84b742eaa43 94 Pfam PF13650 Aspartyl protease 20 62 3.6E-5 T 23-10-2018 VMUT_1949 8469d462657e4e0a4dcd53ab3f4839fa 110 Gene3D G3DSA:2.10.260.10 10 96 1.5E-11 T 23-10-2018 VMUT_0731 208dc152edd98237744c909a94161425 354 Pfam PF06626 Protein of unknown function (DUF1152) 14 311 4.9E-100 T 23-10-2018 IPR010581 Protein of unknown function DUF1152 VMUT_1027 ad17e31d9dfeeca664dc13cfd341993e 394 Pfam PF05317 Thermopsin 143 370 2.3E-32 T 23-10-2018 IPR007981 Peptidase A5, thermopsin VMUT_0694 dbfc7c90d9440089392a63f760b84a32 374 Pfam PF00155 Aminotransferase class I and II 51 353 3.8E-23 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VMUT_0694 dbfc7c90d9440089392a63f760b84a32 374 Gene3D G3DSA:3.40.640.10 55 269 1.5E-88 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VMUT_0694 dbfc7c90d9440089392a63f760b84a32 374 Gene3D G3DSA:3.90.1150.10 18 369 1.5E-88 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VMUT_0694 dbfc7c90d9440089392a63f760b84a32 374 SUPERFAMILY SSF53383 17 369 9.94E-77 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VMUT_1591 93e50ff4a937e6b8a48c50bf1939b44c 117 Pfam PF07282 Putative transposase DNA-binding domain 24 90 3.7E-19 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal VMUT_1591 93e50ff4a937e6b8a48c50bf1939b44c 117 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 2 51 1.2E-6 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal VMUT_0765 9836da42189fe99e4a429ca0b0f3b0fb 443 Pfam PF01385 Probable transposase 174 289 4.5E-34 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 VMUT_0765 9836da42189fe99e4a429ca0b0f3b0fb 443 Pfam PF07282 Putative transposase DNA-binding domain 305 371 3.8E-18 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal VMUT_2103 bf326ae7225a7dcd8a9e15af20de5633 147 Gene3D G3DSA:1.20.58.1610 8 135 2.1E-9 T 23-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_2103 bf326ae7225a7dcd8a9e15af20de5633 147 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 41 130 2.2E-9 T 23-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_1733 f4d160ed1e62ca364d8ac68e7e09bbcc 840 Pfam PF01496 V-type ATPase 116kDa subunit family 461 574 1.3E-16 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 VMUT_1793 2d7b975ff0dd5d4aaf9616dfe560783e 297 SUPERFAMILY SSF51713 17 242 2.22E-28 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 VMUT_1793 2d7b975ff0dd5d4aaf9616dfe560783e 297 Gene3D G3DSA:3.20.20.105 1 228 9.3E-15 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 VMUT_0563 90b3a186880cec8846bff5b1e1f9dca8 124 Pfam PF01022 Bacterial regulatory protein, arsR family 40 82 4.3E-8 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VMUT_0563 90b3a186880cec8846bff5b1e1f9dca8 124 Gene3D G3DSA:1.10.10.10 38 104 3.6E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_0563 90b3a186880cec8846bff5b1e1f9dca8 124 SUPERFAMILY SSF46785 40 110 5.74E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_1946 d4b104593d0e6e492d92fb9fb543fd57 204 Pfam PF00156 Phosphoribosyl transferase domain 73 182 6.4E-12 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 VMUT_1946 d4b104593d0e6e492d92fb9fb543fd57 204 SUPERFAMILY SSF53271 23 182 3.02E-24 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like VMUT_1946 d4b104593d0e6e492d92fb9fb543fd57 204 Gene3D G3DSA:3.40.50.2020 15 202 8.4E-38 T 23-10-2018 VMUT_0639 416ae0d48c29d271423361d10e24ed07 290 SMART SM00090 24 262 6.6E-65 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 VMUT_0639 416ae0d48c29d271423361d10e24ed07 290 Gene3D G3DSA:1.10.510.10 163 263 7.2E-22 T 23-10-2018 VMUT_0639 416ae0d48c29d271423361d10e24ed07 290 SUPERFAMILY SSF56112 55 249 4.53E-22 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily VMUT_0639 416ae0d48c29d271423361d10e24ed07 290 Pfam PF01163 RIO1 family 67 247 2.5E-51 T 23-10-2018 VMUT_0639 416ae0d48c29d271423361d10e24ed07 290 Gene3D G3DSA:3.30.200.20 52 154 1.3E-12 T 23-10-2018 VMUT_0618 174e4b0ae4c087a5965dcc11a97e3956 244 Pfam PF01061 ABC-2 type transporter 16 201 3.8E-12 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 VMUT_0138 f0a3bffa124597cff82a9e33fc14ca5a 356 PIRSF PIRSF016495 1 356 1.4E-108 T 23-10-2018 IPR009995 Protein of unknown function DUF1512 VMUT_0138 f0a3bffa124597cff82a9e33fc14ca5a 356 Pfam PF07431 Protein of unknown function (DUF1512) 5 355 1.3E-123 T 23-10-2018 IPR009995 Protein of unknown function DUF1512 VMUT_2186 800fa2daf01174e816208688cdc63182 477 SUPERFAMILY SSF111283 4 472 2.09E-91 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 VMUT_2186 800fa2daf01174e816208688cdc63182 477 Pfam PF01523 Putative modulator of DNA gyrase 22 327 6.7E-50 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 VMUT_2186 800fa2daf01174e816208688cdc63182 477 Gene3D G3DSA:3.30.2290.10 2 210 6.6E-16 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal VMUT_2186 800fa2daf01174e816208688cdc63182 477 PIRSF PIRSF004919 1 475 2.2E-133 T 23-10-2018 IPR025502 TldD VMUT_1065 27ffe558d20d488301f34b2b6e3110b2 344 Pfam PF13641 Glycosyltransferase like family 2 5 196 6.4E-12 T 23-10-2018 VMUT_1065 27ffe558d20d488301f34b2b6e3110b2 344 SUPERFAMILY SSF53448 3 254 1.13E-28 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1065 27ffe558d20d488301f34b2b6e3110b2 344 Gene3D G3DSA:3.90.550.10 2 219 5.2E-26 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1368 819c6c8dbf4bbb04b57726a5ae44e908 262 SUPERFAMILY SSF160104 9 254 2.09E-38 T 23-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 VMUT_1368 819c6c8dbf4bbb04b57726a5ae44e908 262 Pfam PF06314 Acetoacetate decarboxylase (ADC) 13 254 3.5E-42 T 23-10-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 VMUT_1368 819c6c8dbf4bbb04b57726a5ae44e908 262 Gene3D G3DSA:2.40.400.10 13 257 2.8E-52 T 23-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 VMUT_0668 55f38b11febe667ba975a7df7d556e75 127 SUPERFAMILY SSF50630 26 108 7.5E-6 T 23-10-2018 IPR021109 Aspartic peptidase domain superfamily VMUT_0668 55f38b11febe667ba975a7df7d556e75 127 Gene3D G3DSA:2.40.70.10 13 122 1.2E-6 T 23-10-2018 IPR021109 Aspartic peptidase domain superfamily VMUT_0668 55f38b11febe667ba975a7df7d556e75 127 Pfam PF13650 Aspartyl protease 18 66 1.0E-6 T 23-10-2018 VMUT_1350 a6a6dc73aecab5b08a17515576c70c0e 329 Gene3D G3DSA:3.50.30.60 168 327 5.5E-33 T 23-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily VMUT_1350 a6a6dc73aecab5b08a17515576c70c0e 329 SUPERFAMILY SSF52317 8 162 5.95E-40 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like VMUT_1350 a6a6dc73aecab5b08a17515576c70c0e 329 SUPERFAMILY SSF141986 184 320 1.31E-31 T 23-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily VMUT_1350 a6a6dc73aecab5b08a17515576c70c0e 329 Gene3D G3DSA:3.40.50.10740 7 164 7.7E-43 T 23-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal VMUT_1350 a6a6dc73aecab5b08a17515576c70c0e 329 PIRSF PIRSF028757 8 329 2.3E-80 T 23-10-2018 IPR003507 Peptidase family S66 VMUT_1350 a6a6dc73aecab5b08a17515576c70c0e 329 Pfam PF02016 LD-carboxypeptidase 20 310 3.9E-63 T 23-10-2018 IPR003507 Peptidase family S66 VMUT_2041 d769b7673bef69d448a2d533c92b9bfc 119 SUPERFAMILY SSF50891 16 116 1.35E-10 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily VMUT_2041 d769b7673bef69d448a2d533c92b9bfc 119 Gene3D G3DSA:2.40.100.20 6 117 3.4E-11 T 23-10-2018 VMUT_1735 d28248400a3494491503d16f10a1be5e 308 Pfam PF03956 Lysine exporter LysO 118 305 6.9E-43 T 23-10-2018 IPR005642 Lysine exporter LysO VMUT_1735 d28248400a3494491503d16f10a1be5e 308 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 199 291 3.0E-19 T 23-10-2018 IPR005642 Lysine exporter LysO VMUT_1601 020f1f32b7fc96a2936d8dd2bdd29a42 247 SUPERFAMILY SSF52096 11 247 3.18E-43 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VMUT_1601 020f1f32b7fc96a2936d8dd2bdd29a42 247 Gene3D G3DSA:3.90.226.10 5 247 1.9E-39 T 23-10-2018 VMUT_1601 020f1f32b7fc96a2936d8dd2bdd29a42 247 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 210 9.4E-26 T 23-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VMUT_0272 8bb42de5aa07d8ec15fb73939c63325b 397 Pfam PF04412 Protein of unknown function (DUF521) 1 388 1.7E-101 T 23-10-2018 IPR007506 Aconitase X catalytic domain, putative VMUT_0822 eb33458a50126eb8d6de5e44a2d2055e 696 Pfam PF09852 Predicted membrane protein (DUF2079) 95 512 6.9E-51 T 23-10-2018 IPR018650 Sulfolobus virus STSV1, Orf64 VMUT_2123 d4604ee8ae956512f7201be331c35af2 200 SUPERFAMILY SSF81301 13 158 1.21E-23 T 23-10-2018 VMUT_2123 d4604ee8ae956512f7201be331c35af2 200 Gene3D G3DSA:3.30.460.40 5 161 3.7E-10 T 23-10-2018 VMUT_2123 d4604ee8ae956512f7201be331c35af2 200 Pfam PF09970 Nucleotidyl transferase of unknown function (DUF2204) 15 193 3.7E-50 T 23-10-2018 IPR018700 Protein of unknown function DUF2204 VMUT_2086 99c26aeca35f31cbd78258d1faa04b3f 484 Gene3D G3DSA:2.40.380.10 367 474 1.0E-8 T 23-10-2018 IPR035930 FomD-like superfamily VMUT_2086 99c26aeca35f31cbd78258d1faa04b3f 484 Pfam PF04167 Protein of unknown function (DUF402) 375 440 1.6E-12 T 23-10-2018 IPR007295 Domain of unknown function DUF402 VMUT_2086 99c26aeca35f31cbd78258d1faa04b3f 484 SUPERFAMILY SSF159234 317 472 1.83E-19 T 23-10-2018 IPR035930 FomD-like superfamily VMUT_2044 9649f09f2b147d45b03d6811c9665a2e 165 SUPERFAMILY SSF103196 24 130 2.27E-8 T 23-10-2018 VMUT_2044 9649f09f2b147d45b03d6811c9665a2e 165 Gene3D G3DSA:3.30.450.30 6 133 5.3E-8 T 23-10-2018 VMUT_1379 c99b45d7fe8d687c3d8d29e7388354f2 310 Gene3D G3DSA:3.20.20.140 67 302 4.9E-29 T 23-10-2018 VMUT_1379 c99b45d7fe8d687c3d8d29e7388354f2 310 Pfam PF04909 Amidohydrolase 97 298 3.7E-18 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VMUT_1379 c99b45d7fe8d687c3d8d29e7388354f2 310 SUPERFAMILY SSF51556 4 298 8.32E-20 T 23-10-2018 IPR032466 Metal-dependent hydrolase VMUT_0059 aa5a196b6a9bd67ea677eea1a6e0e36d 257 Gene3D G3DSA:3.30.2170.10 13 239 1.5E-51 T 23-10-2018 VMUT_0059 aa5a196b6a9bd67ea677eea1a6e0e36d 257 Hamap MF_00801 Endonuclease V [nfi]. 21 232 27.702 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 VMUT_0059 aa5a196b6a9bd67ea677eea1a6e0e36d 257 Pfam PF04493 Endonuclease V 32 222 1.1E-50 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 VMUT_1519 256aea69ebf06a4ae953a76e169fb490 115 PIRSF PIRSF029883 1 112 1.4E-26 T 23-10-2018 IPR025499 Pectin degradation protein KdgF VMUT_1519 256aea69ebf06a4ae953a76e169fb490 115 SUPERFAMILY SSF51182 17 114 2.87E-24 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily VMUT_1519 256aea69ebf06a4ae953a76e169fb490 115 Pfam PF07883 Cupin domain 34 92 1.2E-14 T 23-10-2018 IPR013096 Cupin 2, conserved barrel VMUT_1519 256aea69ebf06a4ae953a76e169fb490 115 Gene3D G3DSA:2.60.120.10 2 109 3.2E-30 T 23-10-2018 IPR014710 RmlC-like jelly roll fold VMUT_1814 1d73b9e7743712a4e44b913bb5700102 493 Pfam PF00361 Proton-conducting membrane transporter 136 405 2.0E-30 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_2146 85792486170ddfaf04251ca8276b85b7 466 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 13 403 7.7E-59 T 23-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 VMUT_1461 e2975d0f77a17529c53bad8bdef5962b 152 Gene3D G3DSA:3.40.50.150 12 146 3.2E-16 T 23-10-2018 VMUT_1461 e2975d0f77a17529c53bad8bdef5962b 152 SUPERFAMILY SSF53335 20 127 5.63E-17 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VMUT_1461 e2975d0f77a17529c53bad8bdef5962b 152 Pfam PF08241 Methyltransferase domain 46 123 2.3E-10 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 VMUT_2224 e02a4cffe807372057fd867ac30c9446 140 SUPERFAMILY SSF57783 6 38 5.95E-6 T 23-10-2018 VMUT_0554 fef0139ac3e3288aceb8ca1e63da776f 188 Pfam PF06197 Protein of unknown function (DUF998) 12 178 5.0E-26 T 23-10-2018 IPR009339 Protein of unknown function DUF998 VMUT_0354 d7f891bb7464a5d2aa3c4133d95c6777 97 SUPERFAMILY SSF74853 13 59 1.96E-5 T 23-10-2018 IPR036415 Lamin tail domain superfamily VMUT_0436 ca1b036e1e5316a4f92b26d615cf0f62 87 Pfam PF04457 Protein of unknown function (DUF504) 25 83 8.9E-15 T 23-10-2018 IPR007547 Uncharacterised protein family UPF0248 VMUT_2152 30df3e36578cdfed20da77cc4133901d 274 Pfam PF04055 Radical SAM superfamily 34 199 1.0E-7 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VMUT_0954 567fe1f99e85da072abc3ba5f63e4665 308 Pfam PF00924 Mechanosensitive ion channel 97 231 4.4E-16 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 VMUT_0954 567fe1f99e85da072abc3ba5f63e4665 308 SUPERFAMILY SSF50182 137 217 1.08E-7 T 23-10-2018 IPR010920 LSM domain superfamily VMUT_0684 c2844f84c112b35d205278dd3672702c 383 Pfam PF01882 Protein of unknown function DUF58 189 258 5.8E-6 T 23-10-2018 IPR002881 Domain of unknown function DUF58 VMUT_1126 f415f526798b5c5244f208a9404c713d 186 Hamap MF_01116 Probable ribosome biogenesis protein . 4 174 29.495 T 23-10-2018 IPR022968 Ribosome biogenesis protein Reactome: R-HSA-6790901 VMUT_1126 f415f526798b5c5244f208a9404c713d 186 Pfam PF04034 Ribosome biogenesis protein, C-terminal 44 156 2.1E-36 T 23-10-2018 IPR007177 Ribosome biogenesis protein, C-terminal Reactome: R-HSA-6790901 VMUT_1126 f415f526798b5c5244f208a9404c713d 186 ProDom PD016638 UPF0293 SIMILAR RNASE YOR006C RNA COMPONENT SACCHAROMYCES P RIKEN CERVISIAE 31 162 2.0E-28 T 23-10-2018 IPR007177 Ribosome biogenesis protein, C-terminal Reactome: R-HSA-6790901 VMUT_0143 2ff74bca02ed7260de8ea7b0f2145af8 63 Pfam PF11520 Chromatin protein Cren7 16 53 5.4E-13 T 23-10-2018 IPR020906 Double-stranded DNA-binding Cren7 GO:0003690|GO:0005737 VMUT_0143 2ff74bca02ed7260de8ea7b0f2145af8 63 Hamap MF_01387 Chromatin protein Cren7 [creN7]. 4 57 15.667 T 23-10-2018 IPR020906 Double-stranded DNA-binding Cren7 GO:0003690|GO:0005737 VMUT_0143 2ff74bca02ed7260de8ea7b0f2145af8 63 Gene3D G3DSA:2.30.30.610 10 55 1.1E-9 T 23-10-2018 IPR038647 Cren7 superfamily VMUT_0178 2ff74bca02ed7260de8ea7b0f2145af8 63 Pfam PF11520 Chromatin protein Cren7 16 53 5.4E-13 T 23-10-2018 IPR020906 Double-stranded DNA-binding Cren7 GO:0003690|GO:0005737 VMUT_0178 2ff74bca02ed7260de8ea7b0f2145af8 63 Hamap MF_01387 Chromatin protein Cren7 [creN7]. 4 57 15.667 T 23-10-2018 IPR020906 Double-stranded DNA-binding Cren7 GO:0003690|GO:0005737 VMUT_0178 2ff74bca02ed7260de8ea7b0f2145af8 63 Gene3D G3DSA:2.30.30.610 10 55 1.1E-9 T 23-10-2018 IPR038647 Cren7 superfamily VMUT_1922 77d863b4f69056168887ddcc259bf9af 177 Pfam PF05942 Archaeal PaREP1/PaREP8 family 24 138 1.2E-20 T 23-10-2018 IPR010268 Archaeal PaREP1 VMUT_1088 e4dbefd144e33529a184f3e63d9225e5 292 Pfam PF01522 Polysaccharide deacetylase 49 249 1.7E-23 T 23-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 VMUT_1088 e4dbefd144e33529a184f3e63d9225e5 292 SUPERFAMILY SSF88713 13 252 1.25E-33 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 VMUT_1061 1136ff7fb308a616633d7d637ebb3e84 385 Gene3D G3DSA:3.40.50.2000 3 205 4.3E-9 T 23-10-2018 VMUT_1061 1136ff7fb308a616633d7d637ebb3e84 385 Gene3D G3DSA:3.40.50.2000 206 357 3.1E-5 T 23-10-2018 VMUT_1061 1136ff7fb308a616633d7d637ebb3e84 385 SUPERFAMILY SSF53756 4 381 3.34E-19 T 23-10-2018 VMUT_1061 1136ff7fb308a616633d7d637ebb3e84 385 Pfam PF13439 Glycosyltransferase Family 4 17 190 1.0E-10 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 VMUT_2303 cb95875b6764a0bcfd83eb224a4c4337 484 Gene3D G3DSA:1.20.1250.20 272 484 4.9E-18 T 23-10-2018 VMUT_2303 cb95875b6764a0bcfd83eb224a4c4337 484 Pfam PF07690 Major Facilitator Superfamily 33 422 8.8E-40 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VMUT_2303 cb95875b6764a0bcfd83eb224a4c4337 484 SUPERFAMILY SSF103473 19 448 5.75E-53 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_2303 cb95875b6764a0bcfd83eb224a4c4337 484 Gene3D G3DSA:1.20.1250.20 22 216 7.5E-33 T 23-10-2018 VMUT_0049 c267cc4ea6e1687c8efd80201b7c8b89 163 Pfam PF05942 Archaeal PaREP1/PaREP8 family 42 152 1.0E-26 T 23-10-2018 IPR010268 Archaeal PaREP1 VMUT_0049 c267cc4ea6e1687c8efd80201b7c8b89 163 Gene3D G3DSA:1.20.120.330 36 162 3.0E-36 T 23-10-2018 VMUT_1270 85538225f79f35384ca83771405381fc 82 SUPERFAMILY SSF101744 9 73 9.77E-16 T 23-10-2018 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 VMUT_1270 85538225f79f35384ca83771405381fc 82 Pfam PF01868 Domain of unknown function UPF0086 10 72 9.0E-12 T 23-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 VMUT_1270 85538225f79f35384ca83771405381fc 82 Gene3D G3DSA:2.30.30.210 8 68 2.6E-11 T 23-10-2018 IPR036980 Ribonuclease P/MRP, subunit p29 superfamily GO:0003723|GO:0004540|GO:0008033|GO:0030677 Reactome: R-HSA-6784531 VMUT_1868 acf3387ad4e959b68e02d1677546e66d 204 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 14 202 1.4E-64 T 23-10-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 VMUT_1868 acf3387ad4e959b68e02d1677546e66d 204 Gene3D G3DSA:3.40.50.10490 7 202 6.3E-56 T 23-10-2018 VMUT_1868 acf3387ad4e959b68e02d1677546e66d 204 Pfam PF01380 SIS domain 43 142 8.8E-18 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 VMUT_1868 acf3387ad4e959b68e02d1677546e66d 204 SUPERFAMILY SSF53697 6 201 1.38E-40 T 23-10-2018 VMUT_1724 e6b995d1bc1a4edbd37e11c65c62e1f7 288 Gene3D G3DSA:3.90.550.10 1 200 1.5E-31 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_1724 e6b995d1bc1a4edbd37e11c65c62e1f7 288 Pfam PF12804 MobA-like NTP transferase domain 4 140 2.1E-22 T 23-10-2018 IPR025877 MobA-like NTP transferase VMUT_1724 e6b995d1bc1a4edbd37e11c65c62e1f7 288 SUPERFAMILY SSF53448 1 196 3.68E-25 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VMUT_2004 7473439fbc66bb837253c69e58d574de 169 Pfam PF05942 Archaeal PaREP1/PaREP8 family 14 141 1.5E-21 T 23-10-2018 IPR010268 Archaeal PaREP1 VMUT_1886 9283d4901228f3a930717994b9bd25ab 177 Pfam PF05942 Archaeal PaREP1/PaREP8 family 17 145 5.0E-20 T 23-10-2018 IPR010268 Archaeal PaREP1 VMUT_1129 f3486b087ab1857e013466acd9621fad 133 Gene3D G3DSA:3.30.70.3370 16 133 6.7E-26 T 23-10-2018 VMUT_1129 f3486b087ab1857e013466acd9621fad 133 ProDom PD006052 RIBOSOMAL S24 40S RIBONUCLEOPROTEIN S24E 30S S24 CDNA RIKEN ACETYLATION 27 81 3.0E-8 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1129 f3486b087ab1857e013466acd9621fad 133 Hamap MF_00545 30S ribosomal protein S24e [rps24e]. 17 117 16.078 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1129 f3486b087ab1857e013466acd9621fad 133 SUPERFAMILY SSF54189 20 117 2.81E-24 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 VMUT_1129 f3486b087ab1857e013466acd9621fad 133 ProSitePatterns PS00529 Ribosomal protein S24e signature. 76 98 - T 23-10-2018 IPR018098 Ribosomal S24e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1129 f3486b087ab1857e013466acd9621fad 133 Pfam PF01282 Ribosomal protein S24e 38 114 5.8E-19 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VMUT_1082 9bdfb7e237849d4c71a7434e2c2ce8a8 359 SUPERFAMILY SSF53756 55 287 6.28E-10 T 23-10-2018 VMUT_1859 a26fa78f759e574b28d96609d4b265cd 361 SUPERFAMILY SSF51905 1 107 1.83E-5 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VMUT_1631 d95caa7b3c1cc5045f97807a9d802969 201 SUPERFAMILY SSF53323 4 193 1.83E-34 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 VMUT_1631 d95caa7b3c1cc5045f97807a9d802969 201 Gene3D G3DSA:3.40.920.10 2 201 2.3E-43 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 VMUT_1631 d95caa7b3c1cc5045f97807a9d802969 201 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 191 1.8E-33 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 VMUT_1332 e5ac9eb560c86a5047c5e5f635152d75 344 Gene3D G3DSA:3.40.50.300 3 157 1.5E-10 T 23-10-2018 VMUT_1332 e5ac9eb560c86a5047c5e5f635152d75 344 SUPERFAMILY SSF52540 6 333 3.38E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_0743 52ef224742724e6ffbc79a4c1643cca5 196 Pfam PF01914 MarC family integral membrane protein 10 194 2.6E-31 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 VMUT_0604 4dd18b2431b68d14b5056069041d5b7c 238 SUPERFAMILY SSF52980 96 157 1.05E-9 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 VMUT_0425 bb8d5a5177e3292921d02a72b40d4797 255 Pfam PF05552 Conserved TM helix 1 37 3.5E-7 T 23-10-2018 IPR008910 Conserved TM helix VMUT_1424 26a281ca2f483814c08b394b899c63ca 145 SUPERFAMILY SSF53323 4 98 6.54E-15 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 VMUT_1424 26a281ca2f483814c08b394b899c63ca 145 Gene3D G3DSA:3.40.920.10 3 144 1.7E-22 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 VMUT_1424 26a281ca2f483814c08b394b899c63ca 145 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 13 98 8.0E-12 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 VMUT_0514 1aa3fb18fcdcfcef716c180bc1d98b68 325 Gene3D G3DSA:3.30.70.3460 196 318 1.4E-16 T 23-10-2018 VMUT_0514 1aa3fb18fcdcfcef716c180bc1d98b68 325 Gene3D G3DSA:3.30.70.3460 66 174 1.8E-16 T 23-10-2018 VMUT_1477 b5766012bb448d90af0e8f775bb5bc90 356 Pfam PF03787 RAMP superfamily 23 350 7.2E-22 T 23-10-2018 IPR005537 CRISPR type III-associated RAMP protein VMUT_1477 b5766012bb448d90af0e8f775bb5bc90 356 TIGRFAM TIGR02580 cas_RAMP_Cmr4: CRISPR type III-B/RAMP module RAMP protein Cmr4 21 352 2.4E-62 T 23-10-2018 IPR013410 CRISPR-associated RAMP Cmr4 VMUT_0744 660d9e8db09c4ef9f7a4300d623e4e94 111 Gene3D G3DSA:2.10.260.10 25 109 2.0E-13 T 23-10-2018 VMUT_1346 959162ec69f3676f3e70b200ef14b16e 138 SUPERFAMILY SSF81593 19 133 2.9E-5 T 23-10-2018 VMUT_1346 959162ec69f3676f3e70b200ef14b16e 138 Gene3D G3DSA:1.20.120.580 2 136 1.6E-11 T 23-10-2018 IPR037038 Bsu32300-like superfamily VMUT_1346 959162ec69f3676f3e70b200ef14b16e 138 Pfam PF01934 Protein of unknown function DUF86 16 131 1.2E-18 T 23-10-2018 IPR008201 Protein of unknown function DUF86 VMUT_1557 42baa75c21b9cfb10055d33c0f9e459f 272 Pfam PF13478 XdhC Rossmann domain 90 228 5.6E-23 T 23-10-2018 IPR027051 XdhC Rossmann domain VMUT_1557 42baa75c21b9cfb10055d33c0f9e459f 272 Gene3D G3DSA:3.40.50.720 88 250 2.0E-27 T 23-10-2018 VMUT_0709 9bd03a072b3c25a48cd0337141b3f39b 161 Pfam PF09821 C-terminal AAA-associated domain 35 151 5.0E-29 T 23-10-2018 IPR018632 C-terminal AAA-associated domain VMUT_1965 0eb7a5998a41081052a59d02320d66e2 264 SUPERFAMILY SSF46785 196 256 1.17E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VMUT_1965 0eb7a5998a41081052a59d02320d66e2 264 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 197 253 3.7E-9 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal VMUT_1965 0eb7a5998a41081052a59d02320d66e2 264 Gene3D G3DSA:1.10.10.10 188 263 5.3E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VMUT_0750 dc5a05818d42485d54bdfd8d33e614af 100 Hamap MF_00305 Signal recognition particle 19 kDa protein [srp19]. 1 89 25.204 T 23-10-2018 IPR022938 Signal recognition particle, SRP19 subunit, archaeal-type VMUT_0750 dc5a05818d42485d54bdfd8d33e614af 100 Pfam PF01922 SRP19 protein 1 88 5.5E-20 T 23-10-2018 IPR002778 Signal recognition particle, SRP19 subunit GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 VMUT_0750 dc5a05818d42485d54bdfd8d33e614af 100 SUPERFAMILY SSF69695 1 96 1.14E-18 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 VMUT_0750 dc5a05818d42485d54bdfd8d33e614af 100 Gene3D G3DSA:3.30.56.30 1 99 1.5E-24 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 VMUT_1416 1e89a679e45bb3b92d84aae64eb944ee 206 Pfam PF01810 LysE type translocator 16 200 3.9E-31 T 23-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 VMUT_2347 9fcf71391cfbf93748f69d44b9fe9e95 49 Gene3D G3DSA:3.40.50.300 1 49 4.3E-13 T 23-10-2018 VMUT_2347 9fcf71391cfbf93748f69d44b9fe9e95 49 SUPERFAMILY SSF52540 3 49 6.21E-14 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VMUT_2347 9fcf71391cfbf93748f69d44b9fe9e95 49 Pfam PF00005 ABC transporter 20 49 1.8E-6 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VMUT_0685 7193ffc137af276739ee22f8dfe2efba 438 Gene3D G3DSA:3.10.620.30 301 412 4.2E-12 T 23-10-2018 VMUT_0685 7193ffc137af276739ee22f8dfe2efba 438 SUPERFAMILY SSF54001 303 400 9.32E-12 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily VMUT_0685 7193ffc137af276739ee22f8dfe2efba 438 Pfam PF01841 Transglutaminase-like superfamily 319 394 4.8E-10 T 23-10-2018 IPR002931 Transglutaminase-like VMUT_0685 7193ffc137af276739ee22f8dfe2efba 438 SMART SM00460 327 396 1.6E-4 T 23-10-2018 IPR002931 Transglutaminase-like VMUT_1917 0129acae5e63f80669bc4e40fbe94c28 247 SUPERFAMILY SSF51658 30 207 4.97E-9 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily VMUT_1917 0129acae5e63f80669bc4e40fbe94c28 247 Gene3D G3DSA:3.20.20.150 21 222 7.6E-10 T 23-10-2018 VMUT_1653 374633410c70d28d1bc9f66e261516aa 276 PRINTS PR00721 Stomatin signature 86 107 2.3E-44 T 23-10-2018 IPR001972 Stomatin family GO:0016020 VMUT_1653 374633410c70d28d1bc9f66e261516aa 276 PRINTS PR00721 Stomatin signature 165 183 2.3E-44 T 23-10-2018 IPR001972 Stomatin family GO:0016020 VMUT_1653 374633410c70d28d1bc9f66e261516aa 276 PRINTS PR00721 Stomatin signature 141 164 2.3E-44 T 23-10-2018 IPR001972 Stomatin family GO:0016020 VMUT_1653 374633410c70d28d1bc9f66e261516aa 276 PRINTS PR00721 Stomatin signature 184 205 2.3E-44 T 23-10-2018 IPR001972 Stomatin family GO:0016020 VMUT_1653 374633410c70d28d1bc9f66e261516aa 276 PRINTS PR00721 Stomatin signature 39 61 2.3E-44 T 23-10-2018 IPR001972 Stomatin family GO:0016020 VMUT_1653 374633410c70d28d1bc9f66e261516aa 276 PRINTS PR00721 Stomatin signature 121 138 2.3E-44 T 23-10-2018 IPR001972 Stomatin family GO:0016020 VMUT_1653 374633410c70d28d1bc9f66e261516aa 276 PRINTS PR00721 Stomatin signature 209 232 2.3E-44 T 23-10-2018 IPR001972 Stomatin family GO:0016020 VMUT_1653 374633410c70d28d1bc9f66e261516aa 276 Pfam PF01145 SPFH domain / Band 7 family 36 205 2.3E-34 T 23-10-2018 IPR001107 Band 7 domain VMUT_1653 374633410c70d28d1bc9f66e261516aa 276 Gene3D G3DSA:3.30.479.30 60 191 4.6E-40 T 23-10-2018 VMUT_1653 374633410c70d28d1bc9f66e261516aa 276 SUPERFAMILY SSF117892 63 196 6.67E-37 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily VMUT_1653 374633410c70d28d1bc9f66e261516aa 276 SMART SM00244 32 189 1.5E-50 T 23-10-2018 IPR001107 Band 7 domain VMUT_2010 f86d5222320262f565e9cb06b25678f3 137 Gene3D G3DSA:3.30.460.10 2 92 3.7E-6 T 23-10-2018 VMUT_2010 f86d5222320262f565e9cb06b25678f3 137 SUPERFAMILY SSF81301 4 92 1.25E-9 T 23-10-2018 VMUT_0044 f2bf23cec92282454612c8498a242155 357 Pfam PF07282 Putative transposase DNA-binding domain 292 348 1.2E-10 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal VMUT_1087 5c4603095acb51a7b6d79e4e8f5dc26b 390 SUPERFAMILY SSF53756 68 382 3.86E-8 T 23-10-2018 VMUT_1087 5c4603095acb51a7b6d79e4e8f5dc26b 390 Gene3D G3DSA:3.40.50.2000 212 373 6.1E-8 T 23-10-2018 VMUT_1140 45b6231c16e016ecc852d43148a7fa18 94 Pfam PF07788 PD-(D/E)XK nuclease superfamily 23 87 7.0E-15 T 23-10-2018 IPR012431 PD-(D/E)XK nuclease VMUT_1821 f7244c8a4c1e2e2ba8ba20bbbdbe00dc 154 PIRSF PIRSF014422 4 153 2.2E-49 T 23-10-2018 IPR016618 Uncharacterised conserved protein UCP014422 VMUT_2134 751f44a62e682aaef4d0b53a5fe6db9c 631 PIRSF PIRSF006060 478 613 1000.0 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_2134 751f44a62e682aaef4d0b53a5fe6db9c 631 PIRSF PIRSF006060 1 503 4.5E-67 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_2134 751f44a62e682aaef4d0b53a5fe6db9c 631 Pfam PF13520 Amino acid permease 27 454 1.1E-43 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VMUT_2134 751f44a62e682aaef4d0b53a5fe6db9c 631 Gene3D G3DSA:1.20.1740.10 21 483 2.5E-67 T 23-10-2018 VMUT_2247 444615ce474604058e09df392b75355a 488 SUPERFAMILY SSF103473 32 483 1.57E-75 T 23-10-2018 IPR036259 MFS transporter superfamily VMUT_2247 444615ce474604058e09df392b75355a 488 Gene3D G3DSA:1.10.286.90 230 259 5.2E-7 T 23-10-2018 VMUT_2247 444615ce474604058e09df392b75355a 488 Pfam PF00083 Sugar (and other) transporter 78 485 3.3E-48 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VMUT_1290 21d0f620a09a33973fcbbe588ce6d4be 232 Pfam PF03692 Putative zinc- or iron-chelating domain 9 103 5.6E-8 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein VMUT_1040 8411a451022dd9acf03bed182eefe343 203 Pfam PF07760 Protein of unknown function (DUF1616) 86 190 1.6E-19 T 23-10-2018 IPR011674 Domain of unknown function DUF1616 VMUT_1522 ddbf6e404b8e519cd84876e9880f5db4 94 Pfam PF13710 ACT domain 20 77 2.6E-11 T 23-10-2018 VMUT_0941 84a9e6e2b462434c415298206efd64aa 395 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 55 395 18.66 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_0941 84a9e6e2b462434c415298206efd64aa 395 Pfam PF00146 NADH dehydrogenase 79 388 2.7E-84 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VMUT_2187 39233d0e30fcdc49506ca41e00bce72a 140 Pfam PF03703 Bacterial PH domain 57 128 2.8E-4 T 23-10-2018 IPR005182 Domain of unknown function DUF304 VMUT_1104 f7344a50191fcf73f12595046e8b3ddd 299 Pfam PF07760 Protein of unknown function (DUF1616) 143 291 7.8E-14 T 23-10-2018 IPR011674 Domain of unknown function DUF1616 VMUT_0649 3c665a21fcab85ff5419506f9e1e1c70 202 Pfam PF12007 Protein of unknown function (DUF3501) 10 191 9.7E-47 T 23-10-2018 IPR021890 Protein of unknown function DUF3501 VMUT_1574 8fe8905da4744281d9d65bd2fd426756 355 Gene3D G3DSA:3.40.1280.30 90 272 1.1E-7 T 23-10-2018 IPR038459 tRNA methyltransferase TRM10-type domain superfamily VMUT_1574 8fe8905da4744281d9d65bd2fd426756 355 PIRSF PIRSF018978 2 344 8.5E-48 T 23-10-2018 IPR016742 tRNA methyltransferase, archaea GO:0008175|GO:0030488 VMUT_1292 fa15bc126402a1affeae2faef74d8a11 289 Pfam PF01061 ABC-2 type transporter 13 252 1.5E-33 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 VMUT_1292 fa15bc126402a1affeae2faef74d8a11 289 PIRSF PIRSF006648 1 287 2.3E-80 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 VMUT_1713 8cbb6a4d57e64f2f07d00f6060eef02f 159 Pfam PF05942 Archaeal PaREP1/PaREP8 family 24 147 3.4E-27 T 23-10-2018 IPR010268 Archaeal PaREP1 VMUT_1138 b3341e61050f6e58f8d1edc951db6603 120 Gene3D G3DSA:2.10.260.10 20 106 1.3E-11 T 23-10-2018 VMUT_1138 b3341e61050f6e58f8d1edc951db6603 120 SUPERFAMILY SSF89447 72 100 3.14E-5 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily VMUT_1546 ca64c0bca1f69aeee2bbc43a583a00a3 149 Pfam PF05942 Archaeal PaREP1/PaREP8 family 17 65 5.1E-16 T 23-10-2018 IPR010268 Archaeal PaREP1 VMUT_0569 ed60b03b60ab9e9a8f48a7e7f51bbe93 171 Pfam PF07680 TQO small subunit DoxA 30 158 1.5E-38 T 23-10-2018 IPR011636 Thiosulphate:quinone oxidoreductase small subunit DoxA KEGG: 00920+1.8.5.2|MetaCyc: PWY-5303 VMUT_0073 fdfa6ab7b80a76bdc44aa90cf8fe99fb 186 Pfam PF05942 Archaeal PaREP1/PaREP8 family 21 146 3.5E-31 T 23-10-2018 IPR010268 Archaeal PaREP1 VMUT_0199 169ddcaa31618e3783d4b7bc3fbaa735 316 SUPERFAMILY SSF56235 24 310 5.66E-78 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VMUT_0199 169ddcaa31618e3783d4b7bc3fbaa735 316 Pfam PF01112 Asparaginase 6 304 2.1E-85 T 23-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 VMUT_0199 169ddcaa31618e3783d4b7bc3fbaa735 316 Gene3D G3DSA:3.60.20.30 177 313 4.3E-43 T 23-10-2018 VMUT_1353 b467ae548f33ee4256af1b20daa6cee2 169 Gene3D G3DSA:3.10.129.10 33 169 2.2E-34 T 23-10-2018 VMUT_1353 b467ae548f33ee4256af1b20daa6cee2 169 Pfam PF03061 Thioesterase superfamily 74 150 8.4E-16 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 VMUT_1353 b467ae548f33ee4256af1b20daa6cee2 169 SUPERFAMILY SSF54637 33 162 9.91E-32 T 23-10-2018 IPR029069 HotDog domain superfamily VMUT_1353 b467ae548f33ee4256af1b20daa6cee2 169 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 44 155 2.3E-23 T 23-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 VMUT_0042 c744a2f43378a1622a814f110249f315 114 Gene3D G3DSA:3.40.50.1010 1 111 1.6E-18 T 23-10-2018 VMUT_0042 c744a2f43378a1622a814f110249f315 114 Pfam PF01850 PIN domain 2 109 9.6E-7 T 23-10-2018 IPR002716 PIN domain VMUT_0042 c744a2f43378a1622a814f110249f315 114 SUPERFAMILY SSF88723 2 109 3.27E-13 T 23-10-2018 IPR029060 PIN-like domain superfamily VMUT_1882 d7759d992699cec43b4aba97aa0b35cd 235 SUPERFAMILY SSF56300 43 226 1.27E-9 T 23-10-2018 VMUT_1925 349097a2f11f759bd5f5bcb8bfc9feb5 107 Gene3D G3DSA:2.10.260.10 6 94 3.9E-14 T 23-10-2018 VMUT_1119 7542ad415534c9a2ab9c224e4e00426b 48 SUPERFAMILY SSF88723 3 40 3.08E-6 T 23-10-2018 IPR029060 PIN-like domain superfamily VMUT_1068 8c6ab3cabdd218694f2c9a8893d9aeae 122 Gene3D G3DSA:2.40.70.10 1 118 3.3E-6 T 23-10-2018 IPR021109 Aspartic peptidase domain superfamily VMUT_0591 f2fe6e724b012d610d6813742f673751 252 Pfam PF01930 Domain of unknown function DUF83 79 229 8.0E-10 T 23-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 VMUT_0591 f2fe6e724b012d610d6813742f673751 252 Gene3D G3DSA:3.90.320.10 56 231 1.9E-9 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal VMUT_0250 33c0dae5a5355e7ba312e1d8efe38005 149 Pfam PF10015 Uncharacterized protein conserved in archaea (DUF2258) 36 108 2.5E-23 T 23-10-2018 IPR017140 Uncharacterised conserved protein UCP037214 VMUT_0722 fb8beb7ea2297c943878b90b7866c875 296 Pfam PF01384 Phosphate transporter family 22 289 6.6E-18 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 VMUT_2236 7da1cb067c52d549f5408fad4c95df7c 312 PIRSF PIRSF005355 1 305 2.3E-51 T 23-10-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 VMUT_2236 7da1cb067c52d549f5408fad4c95df7c 312 Pfam PF01040 UbiA prenyltransferase family 22 255 4.5E-23 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 VMUT_2131 d168f1de58b1c854a9c96e3977b87d5e 136 SUPERFAMILY SSF81301 11 90 2.78E-7 T 23-10-2018 VMUT_2116 6d584b73de39181748ca1e2dca82a3bc 92 Pfam PF03477 ATP cone domain 4 69 2.8E-7 T 23-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 VMUT_0416 8d967a109a5b2656cdde29b6d0b4382d 486 SUPERFAMILY SSF58104 8 246 2.48E-8 T 23-10-2018 VMUT_0219 830c7d0e57c6628c4447bc46a6886990 158 Pfam PF07849 Protein of unknown function (DUF1641) 115 153 1.9E-16 T 23-10-2018 IPR012440 Protein of unknown function DUF1641 VMUT_1486 cb19920c694fbbfe1d8897ab35769aa1 226 SUPERFAMILY SSF160980 4 223 1.15E-11 T 23-10-2018 VMUT_0261 ba01be1b57fa6ab88613f9cb902813fd 479 Gene3D G3DSA:1.25.40.10 116 395 2.0E-5 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VMUT_0159 59fb56098724753dd6cacb3efbe127c0 80 Pfam PF07362 Post-segregation antitoxin CcdA 7 61 1.3E-7 T 23-10-2018 IPR009956 Post-segregation antitoxin CcdA VMUT_1279 58964796785263956a26a276813cca77 291 Gene3D G3DSA:1.10.357.140 9 161 1.4E-10 T 23-10-2018 VMUT_1279 58964796785263956a26a276813cca77 291 Pfam PF01040 UbiA prenyltransferase family 22 269 3.3E-25 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 VMUT_0050 3193f91a7b7da97dd6299330b0d67bb8 210 Pfam PF16955 Ferrous iron uptake permease, iron-lead transporter 2 209 1.5E-102 T 23-10-2018 IPR031594 Putative iron/lead transporter VMUT_0481 8a1557f4da21db3e95cf06bbd44dcf93 326 Pfam PF01925 Sulfite exporter TauE/SafE 15 284 2.4E-41 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 VMUT_1710 1bb11b1ba097812e73206091c758fa7e 98 Pfam PF05942 Archaeal PaREP1/PaREP8 family 12 66 4.3E-9 T 23-10-2018 IPR010268 Archaeal PaREP1 VMUT_1231 9477b30d314c9d8605eeda65f5232f60 308 SUPERFAMILY SSF58104 30 189 1.86E-6 T 23-10-2018 VMUT_0207 a0aa82164487b0afe2a7bf1a907ef9de 100 SUPERFAMILY SSF103196 2 87 4.19E-6 T 23-10-2018 VMUT_1614 17b3434b57c0de06a3213b666a0f50d2 303 Pfam PF01940 Integral membrane protein DUF92 25 282 1.4E-56 T 23-10-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 VMUT_0630 8908ef9c6f2a90b48136ece9b2513bb0 311 Pfam PF04981 NMD3 family 5 227 4.2E-37 T 23-10-2018 IPR007064 Nmd3, N-terminal VMUT_0480 ca0d92ab89e9cc4a1e32db865e1cf6d9 313 Pfam PF01925 Sulfite exporter TauE/SafE 29 300 1.1E-38 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 VMUT_1394 8d16358e8e03952e3681eddc6fdb1e5c 241 Gene3D G3DSA:3.30.70.3120 70 237 6.4E-7 T 23-10-2018 VMUT_1983 5bb60f168bbed3f79c4fe1ee43095ba0 98 Gene3D G3DSA:1.20.120.580 2 84 6.3E-6 T 23-10-2018 IPR037038 Bsu32300-like superfamily VMUT_0593 dc4a09aca4315cb3732800f0c370b7bd 272 Pfam PF00924 Mechanosensitive ion channel 74 253 1.7E-8 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 VMUT_1509 57a558d215735b8a321d621f34f23369 372 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 12 236 5.8E-14 T 23-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 VMUT_1475 a1a359d4c8ffd4437799752eba53845d 321 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 33 50 6.9E-4 T 23-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal VMUT_0321 7a8ac4e8b7a3a683c41eb2da3f7e1647 141 Pfam PF01986 Domain of unknown function DUF123 26 109 2.5E-12 T 23-10-2018 IPR002837 Protein of unknown function DUF123 VMUT_1739 44e04a032073d37d43c7a660df87252c 175 Pfam PF01385 Probable transposase 82 146 6.0E-10 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 VMUT_1874 f12194bb4ee793075233fecf4957f1db 609 Pfam PF09852 Predicted membrane protein (DUF2079) 31 436 1.8E-51 T 23-10-2018 IPR018650 Sulfolobus virus STSV1, Orf64 VMUT_1108 40ba3f7e156cef414dfe6fcc43481be9 619 SUPERFAMILY SSF49464 206 256 1.49E-6 T 23-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily VMUT_0959 3a82f74648d0aa7c24813c992f1b805d 652 Pfam PF04312 Protein of unknown function (DUF460) 217 365 3.9E-47 T 23-10-2018 IPR007408 Protein of unknown function DUF460 VMUT_0331 226a1248f02f3723af9b3e226912c084 265 Pfam PF01061 ABC-2 type transporter 16 219 3.9E-15 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062