locus-tag	class	description
AKJ08_0001	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AKJ08_0005	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AKJ08_0006	ENOG4105K46	50S ribosomal protein l27
AKJ08_0007	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AKJ08_0010	ENOG4105ECY	inositol monophosphatase
AKJ08_0011	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AKJ08_0012	ENOG4108VPT	UPF0234 protein
AKJ08_0013	ENOG4105CN5	Metallo-Beta-Lactamase
AKJ08_0016	ENOG4105DN3	alpha-2-macroglobulin domain protein
AKJ08_0017	ENOG4105DN3	alpha-2-macroglobulin domain protein
AKJ08_0021	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AKJ08_0024	ENOG4105BZU	Histidine kinase
AKJ08_0027	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AKJ08_0028	ENOG4105C37	(CBS) domain
AKJ08_0029	ENOG4107G87	m6 family metalloprotease domain protein
AKJ08_0031	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
AKJ08_0032	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
AKJ08_0033	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AKJ08_0035	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
AKJ08_0044	ENOG4107G87	m6 family metalloprotease domain protein
AKJ08_0045	ENOG4107G87	m6 family metalloprotease domain protein
AKJ08_0053	ENOG4107R72	Ceramidase
AKJ08_0054	ENOG4105GKE	subunit e
AKJ08_0056	ENOG4105DF2	NADH dehydrogenase subunit j
AKJ08_0057	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AKJ08_0058	ENOG4105D65	subunit l
AKJ08_0059	ENOG4105C8S	subunit m
AKJ08_0062	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AKJ08_0063	ENOG4105BZU	Histidine kinase
AKJ08_0064	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AKJ08_0066	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AKJ08_0073	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AKJ08_0074	ENOG4108Z6B	deaminase
AKJ08_0075	ENOG4107QMP	dna polymerase iii subunits gamma and tau
AKJ08_0076	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AKJ08_0077	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AKJ08_0080	ENOG4105DQU	oxidoreductase, subunit beta
AKJ08_0081	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
AKJ08_0087	ENOG4105DSY	exodeoxyribonuclease V, gamma
AKJ08_0088	ENOG4107QKA	exodeoxyribonuclease V beta
AKJ08_0098	ENOG4106VK6	Flagellar motor protein
AKJ08_0099	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AKJ08_0100	ENOG4105CTD	carboxy-peptidase
AKJ08_0102	ENOG4105C26	Dehydrogenase
AKJ08_0103	ENOG4106WTF	Glycosyl transferase, family 2
AKJ08_0104	ENOG4105E0M	Sulfatase
AKJ08_0107	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
AKJ08_0116	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
AKJ08_0117	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
AKJ08_0122	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AKJ08_0125	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AKJ08_0127	ENOG4105C2J	ABC transporter
AKJ08_0129	ENOG4105CZX	twitching motility protein
AKJ08_0130	ENOG4107QX3	carboxylase
AKJ08_0133	ENOG4105DJT	lAO AO transport system ATPase
AKJ08_0134	ENOG4105C08	Histidine kinase
AKJ08_0135	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
AKJ08_0136	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AKJ08_0138	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AKJ08_0139	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
AKJ08_0150	ENOG4105C34	Pseudouridine synthase
AKJ08_0151	ENOG4105DJ0	Poly(A) Polymerase
AKJ08_0153	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AKJ08_0154	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AKJ08_0155	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AKJ08_0158	ENOG4106RGN	vegetative protein
AKJ08_0162	ENOG4105C8Y	Acetylornithine aminotransferase
AKJ08_0163	ENOG4105DBV	ornithine carbamoyltransferase
AKJ08_0165	ENOG4105E08	Glycoside hydrolase, family 9
AKJ08_0167	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AKJ08_0168	ENOG4105CFG	Acts as a chaperone (By similarity)
AKJ08_0172	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AKJ08_0173	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AKJ08_0185	ENOG4108RRZ	Transcription elongation factor GreB
AKJ08_0187	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AKJ08_0188	ENOG4105JFG	SpoIID LytB domain protein
AKJ08_0191	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AKJ08_0192	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AKJ08_0193	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AKJ08_0198	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AKJ08_0207	ENOG4105DA4	cytochrome c-type biogenesis protein
AKJ08_0208	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AKJ08_0210	ENOG41060IM	Heme exporter protein
AKJ08_0212	ENOG4105CJ1	ABC, transporter
AKJ08_0213	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AKJ08_0216	ENOG4107QNM	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
AKJ08_0217	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
AKJ08_0219	ENOG4105DVY	radical SAM domain protein
AKJ08_0220	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
AKJ08_0222	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
AKJ08_0223	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
AKJ08_0224	ENOG4105E63	Pfam:DUF178
AKJ08_0227	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AKJ08_0230	ENOG4105EXC	Acyl-transferase
AKJ08_0243	ENOG4105CEY	Amp-dependent synthetase and ligase
AKJ08_0245	ENOG4105D3Q	Sugar transferase
AKJ08_0252	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AKJ08_0253	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AKJ08_0254	ENOG4105DFA	alanine racemase domain protein
AKJ08_0260	ENOG4108IDZ	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AKJ08_0262	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AKJ08_0265	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
AKJ08_0267	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AKJ08_0268	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AKJ08_0270	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AKJ08_0272	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AKJ08_0273	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AKJ08_0277	ENOG4105MGM	doxx family
AKJ08_0280	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AKJ08_0281	ENOG4105GRZ	Ycii-related protein
AKJ08_0283	ENOG4105CHP	RNA polymerase
AKJ08_0285	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
AKJ08_0290	ENOG4105C9M	aspartyl-trna synthetase
AKJ08_0291	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
AKJ08_0294	ENOG4105D4A	Cell wall formation (By similarity)
AKJ08_0295	ENOG4105CBD	Diacylglycerol kinase
AKJ08_0296	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AKJ08_0303	ENOG4105C0D	helicase
AKJ08_0304	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AKJ08_0305	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AKJ08_0309	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
AKJ08_0311	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AKJ08_0313	ENOG4105E55	glycerol-3-phosphate acyltransferase
AKJ08_0314	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AKJ08_0315	ENOG4105BZU	Histidine kinase
AKJ08_0317	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AKJ08_0319	ENOG410801F	ribosomal-protein-alanine acetyltransferase
AKJ08_0320	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AKJ08_0323	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AKJ08_0327	ENOG410826D	Involved in DNA repair and RecF pathway recombination (By similarity)
AKJ08_0328	ENOG4108RG3	short-chain dehydrogenase reductase
AKJ08_0329	ENOG4105IQ5	FAD linked oxidase domain protein
AKJ08_0332	ENOG4105CHR	reductase
AKJ08_0334	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AKJ08_0335	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AKJ08_0339	ENOG4105EU0	Major facilitator Superfamily
AKJ08_0340	ENOG4105CVJ	phosphoglycerate mutase
AKJ08_0342	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AKJ08_0343	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AKJ08_0344	ENOG4105KTH	gatB Yqey
AKJ08_0347	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AKJ08_0348	ENOG4107S2Z	UPF0761 membrane protein
AKJ08_0349	ENOG4105C03	ribonuclease
AKJ08_0355	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AKJ08_0357	ENOG4107RN3	metallophosphoesterase
AKJ08_0358	ENOG4105EQK	-acetyltransferase
AKJ08_0360	ENOG4107R39	(ABC) transporter
AKJ08_0361	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AKJ08_0363	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AKJ08_0369	ENOG4108IXY	short-chain dehydrogenase reductase
AKJ08_0371	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AKJ08_0380	ENOG4105D82	Glutamate dehydrogenase
AKJ08_0387	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AKJ08_0390	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AKJ08_0391	ENOG4105DXX	methyltransferase
AKJ08_0392	ENOG4105HDK	L-asparaginase
AKJ08_0397	ENOG4108JUA	Transcriptional regulator
AKJ08_0398	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AKJ08_0403	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AKJ08_0404	ENOG4105CHV	Transcription elongation factor NusA
AKJ08_0406	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AKJ08_0408	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AKJ08_0409	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AKJ08_0410	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AKJ08_0411	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AKJ08_0421	ENOG4105CD8	aminopeptidase N
AKJ08_0422	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AKJ08_0424	ENOG4105C83	adenylosuccinate lyase
AKJ08_0425	ENOG4105KPY	Small multidrug resistance protein
AKJ08_0426	ENOG4105C8V	SAICAR synthetase
AKJ08_0429	ENOG4107S6Z	Na H antiporter
AKJ08_0430	ENOG4105C0H	protease
AKJ08_0432	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AKJ08_0436	ENOG4105NBF	ammecr1 domain protein
AKJ08_0440	ENOG4105C0D	helicase
AKJ08_0441	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AKJ08_0443	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AKJ08_0444	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AKJ08_0445	ENOG4105TNG	K13735 adhesin invasin
AKJ08_0448	ENOG4108S93	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AKJ08_0449	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AKJ08_0452	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AKJ08_0455	ENOG4105CHU	acetyl-coa acetyltransferase
AKJ08_0456	ENOG4105C26	Dehydrogenase
AKJ08_0457	ENOG4105E39	Enoyl-CoA hydratase
AKJ08_0459	ENOG4108Z9K	Osmotically inducible protein
AKJ08_0462	ENOG4105D9P	serine threonine protein kinase
AKJ08_0465	ENOG4105E39	Enoyl-CoA hydratase
AKJ08_0466	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AKJ08_0469	ENOG4105C6K	Malic enzyme
AKJ08_0486	ENOG4105E0R	Deoxyhypusine synthase
AKJ08_0489	ENOG4105BZU	Histidine kinase
AKJ08_0493	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AKJ08_0495	ENOG4105C5H	ABC transporter
AKJ08_0498	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AKJ08_0501	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AKJ08_0502	ENOG4108WBT	adenosyltransferase
AKJ08_0505	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AKJ08_0509	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AKJ08_0514	ENOG4108ZG0	Ompa motb domain protein
AKJ08_0516	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AKJ08_0517	ENOG4107QM5	aconitate hydratase
AKJ08_0519	ENOG4105NXH	GreA GreB family elongation factor
AKJ08_0522	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AKJ08_0527	ENOG4105DPX	Hydrogenase, large subunit
AKJ08_0530	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
AKJ08_0531	ENOG4105CQS	hydrogenase expression formation protein HypD
AKJ08_0534	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
AKJ08_0535	ENOG4107RSS	Hydrogenase accessory protein HypB
AKJ08_0545	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AKJ08_0546	ENOG4105BZU	Histidine kinase
AKJ08_0550	ENOG4105ED1	spovr family
AKJ08_0552	ENOG4105CYN	Serine protein kinase
AKJ08_0553	ENOG41081YB	ApbE family
AKJ08_0554	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AKJ08_0556	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
AKJ08_0560	ENOG4108Q9H	CobQ/CobB/MinD/ParA nucleotide binding domain
AKJ08_0561	ENOG4105DAP	Nicotinate phosphoribosyltransferase
AKJ08_0564	ENOG4108NVM	synthesis repressor PhaR
AKJ08_0566	ENOG4108ZX6	Electron transport protein SCO1 SenC
AKJ08_0567	ENOG4105E6M	Sulphatase-modifying factor protein
AKJ08_0568	ENOG4107B57	rieske 2fe-2S domain-containing protein
AKJ08_0572	ENOG4107RRZ	synthase
AKJ08_0576	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
AKJ08_0580	ENOG4108Z0Z	intracellular protease Pfpi family
AKJ08_0584	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AKJ08_0586	ENOG4105CN1	protease
AKJ08_0587	ENOG4105D7Z	glutathione synthase
AKJ08_0591	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AKJ08_0593	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
AKJ08_0600	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AKJ08_0602	ENOG4105CZX	twitching motility protein
AKJ08_0607	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AKJ08_0608	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AKJ08_0609	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AKJ08_0611	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AKJ08_0612	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AKJ08_0613	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AKJ08_0615	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AKJ08_0618	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
AKJ08_0620	ENOG4105BZP	glycoside hydrolase 15-related
AKJ08_0622	ENOG4105DIA	mandelate racemase muconate lactonizing
AKJ08_0624	ENOG4105CQB	FAD linked oxidase domain protein
AKJ08_0632	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AKJ08_0639	ENOG4107SFQ	iron-sulfur binding
AKJ08_0640	ENOG4107UQT	molybdopterin oxidoreductase
AKJ08_0643	ENOG4105DCG	PHP domain protein
AKJ08_0645	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AKJ08_0646	ENOG4105C7S	Dehydrogenase
AKJ08_0647	ENOG4107QN2	dihydrolipoyl dehydrogenase
AKJ08_0648	ENOG4105DQE	DNA ligase
AKJ08_0650	ENOG41086UQ	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AKJ08_0651	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
AKJ08_0652	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AKJ08_0653	ENOG4105C1Q	protoporphyrinogen oxidase
AKJ08_0656	ENOG4105D1H	recombination factor protein RarA
AKJ08_0657	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AKJ08_0658	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AKJ08_0661	ENOG4105DR5	peptidase
AKJ08_0662	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AKJ08_0663	ENOG4105CE9	30S ribosomal protein S2
AKJ08_0664	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AKJ08_0665	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AKJ08_0666	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AKJ08_0672	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AKJ08_0677	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
AKJ08_0679	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
AKJ08_0681	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
AKJ08_0682	ENOG4105KG3	cytidine deaminase
AKJ08_0684	ENOG4105DTN	riboflavin biosynthesis protein ribF
AKJ08_0685	ENOG4107QHF	type ii secretion system protein e
AKJ08_0686	ENOG4105CZX	twitching motility protein
AKJ08_0688	ENOG4105BZU	Histidine kinase
AKJ08_0689	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AKJ08_0698	ENOG4106855	Competence protein
AKJ08_0699	ENOG4105DA5	(ABC) transporter
AKJ08_0700	ENOG4106KS4	Sulfatase
AKJ08_0701	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
AKJ08_0702	ENOG4105BZU	Histidine kinase
AKJ08_0703	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AKJ08_0709	ENOG4105E4G	Type IV pilus
AKJ08_0712	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AKJ08_0713	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AKJ08_0714	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AKJ08_0725	ENOG4105M8F	Biopolymer transport protein exbD tolR
AKJ08_0726	ENOG4105E02	MotA TolQ exbB proton channel
AKJ08_0728	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AKJ08_0730	ENOG4108HHA	Transketolase
AKJ08_0732	ENOG4105CAK	Cell division ATP-binding protein ftsE
AKJ08_0733	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
AKJ08_0735	ENOG4108MUZ	hydrolase
AKJ08_0736	ENOG4105CN1	protease
AKJ08_0738	ENOG4105CFG	Acts as a chaperone (By similarity)
AKJ08_0739	ENOG4105CYN	Serine protein kinase
AKJ08_0745	ENOG4108MRH	transcriptional regulatory protein
AKJ08_0749	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AKJ08_0750	ENOG4105BZU	Histidine kinase
AKJ08_0754	ENOG4108UW5	maltose o-acetyltransferase
AKJ08_0760	ENOG4105EE1	crotonyl-CoA reductase
AKJ08_0763	ENOG4105CI0	Citrate lyase
AKJ08_0764	ENOG4105DJG	MaoC domain protein dehydratase
AKJ08_0766	ENOG4105C1G	acyl-Coa dehydrogenase
AKJ08_0768	ENOG4105C37	(CBS) domain
AKJ08_0771	ENOG4105K56	Transcriptional regulator
AKJ08_0773	ENOG4107SC1	transglycosylase
AKJ08_0777	ENOG4107QP8	phosphohexose isomerase
AKJ08_0778	ENOG4105PSQ	Acyl-transferase
AKJ08_0780	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AKJ08_0793	ENOG4105C2M	dna polymerase I
AKJ08_0800	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AKJ08_0801	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AKJ08_0802	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
AKJ08_0803	ENOG4105CDH	Citrulline--aspartate ligase
AKJ08_0804	ENOG4105CH7	arginosuccinase
AKJ08_0807	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AKJ08_0809	ENOG41068WN	
AKJ08_0810	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AKJ08_0811	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
AKJ08_0818	ENOG4105C1J	atp-dependent rna helicase
AKJ08_0822	ENOG4108JQ7	(ABC) transporter
AKJ08_0823	ENOG4105C3U	ABC transporter
AKJ08_0824	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AKJ08_0825	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AKJ08_0831	ENOG4105ERG	peptidase m48, ste24p
AKJ08_0834	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AKJ08_0836	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AKJ08_0839	ENOG4105F8V	Hydrolase, tatD family
AKJ08_0843	ENOG4105DZ0	fad dependent oxidoreductase
AKJ08_0847	ENOG4105CP7	Triose-phosphate isomerase
AKJ08_0852	ENOG4105CEY	Amp-dependent synthetase and ligase
AKJ08_0855	ENOG4105CSU	acyl-Coa dehydrogenase
AKJ08_0857	ENOG4105BZ1	(ABC) transporter
AKJ08_0858	ENOG4105W87	Cbs domain
AKJ08_0860	ENOG4105DN3	alpha-2-macroglobulin domain protein
AKJ08_0861	ENOG4108JQB	penicillin-binding protein 1C
AKJ08_0864	ENOG4108V5V	Serine Threonine protein kinase
AKJ08_0865	ENOG4105EHZ	conserved protein UCP016719
AKJ08_0866	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AKJ08_0868	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AKJ08_0870	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
AKJ08_0871	ENOG4105PGM	cation diffusion facilitator family transporter
AKJ08_0872	ENOG4105CD2	stage iii sporulation protein aa
AKJ08_0874	ENOG4106H78	methyltransferase
AKJ08_0875	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AKJ08_0877	ENOG4105VEQ	Cold shock protein
AKJ08_0879	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AKJ08_0885	ENOG41083CW	dedA protein
AKJ08_0889	ENOG4108I62	cina-like protein
AKJ08_0892	ENOG4105C84	Histidine ammonia-lyase
AKJ08_0893	ENOG4105EAC	phosphoserine phosphatase
AKJ08_0896	ENOG4105C4R	Atp-dependent dna helicase
AKJ08_0898	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AKJ08_0901	ENOG4105DHJ	ABC, transporter
AKJ08_0904	ENOG4105C5I	Dehydrogenase
AKJ08_0909	ENOG4105CI3	gtp-binding protein typa
AKJ08_0915	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AKJ08_0916	ENOG4105C22	threonyL-tRNA synthetase
AKJ08_0917	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AKJ08_0918	ENOG4108A8W	50s ribosomal protein L35
AKJ08_0919	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AKJ08_0920	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AKJ08_0921	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AKJ08_0923	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AKJ08_0924	ENOG4108K5P	(LipO)protein
AKJ08_0926	ENOG4108Z4T	Peptidase M50
AKJ08_0927	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AKJ08_0928	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AKJ08_0929	ENOG4105FE9	pseudouridine synthase
AKJ08_0933	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AKJ08_0934	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AKJ08_0935	ENOG41080XP	Cbs domain
AKJ08_0937	ENOG4105CRQ	synthase (Component I)
AKJ08_0939	ENOG4105FDF	Could be involved in DNA repair (By similarity)
AKJ08_0940	ENOG4105BZU	Histidine kinase
AKJ08_0946	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AKJ08_0963	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AKJ08_0964	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
AKJ08_0965	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
AKJ08_0967	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AKJ08_0972	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
AKJ08_0974	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AKJ08_0975	ENOG4107QI1	Mate efflux family protein
AKJ08_0976	ENOG4105C5S	asparaginyl-tRNA synthetase
AKJ08_0977	ENOG4105C8T	Leucyl-tRNA synthetase
AKJ08_0979	ENOG4108317	Binds directly to 16S ribosomal RNA (By similarity)
AKJ08_0980	ENOG4105DXN	mazG family
AKJ08_0984	ENOG4105CTJ	Metal Dependent Phosphohydrolase
AKJ08_0991	ENOG4105D60	lipoprotein releasing system transmembrane protein
AKJ08_0992	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AKJ08_0993	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AKJ08_0995	ENOG4105D3R	alkyl hydroperoxide reductase
AKJ08_0996	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AKJ08_0997	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AKJ08_0998	ENOG4105C5X	domain protein
AKJ08_1000	ENOG41081FY	multiple antibiotic resistance (MarC)-related
AKJ08_1001	ENOG4105BZ1	(ABC) transporter
AKJ08_1004	ENOG4105DKP	glycosyl transferase, family 9
AKJ08_1005	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
AKJ08_1007	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
AKJ08_1008	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
AKJ08_1009	ENOG4105W49	UPF0434 protein
AKJ08_1010	ENOG4105DSJ	YicC domain protein
AKJ08_1011	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AKJ08_1012	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AKJ08_1018	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AKJ08_1026	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AKJ08_1027	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AKJ08_1028	ENOG4105ETX	regulatoR
AKJ08_1029	ENOG4105CTB	Polyprenyl synthetase
AKJ08_1032	ENOG4107R3N	Filamentation induced by cAMP protein fic
AKJ08_1036	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AKJ08_1038	ENOG4107RFW	hydrolase family 57
AKJ08_1043	ENOG4108QV3	biosynthesis protein
AKJ08_1045	ENOG4105CHW	UPF0052 protein
AKJ08_1046	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AKJ08_1053	ENOG4105D7W	serine acetyltransferase
AKJ08_1057	ENOG4107QQG	Dehydrogenase
AKJ08_1059	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AKJ08_1063	ENOG4105CFG	Acts as a chaperone (By similarity)
AKJ08_1064	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AKJ08_1069	ENOG4105DB7	PHP domain protein
AKJ08_1070	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AKJ08_1071	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AKJ08_1072	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AKJ08_1073	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AKJ08_1074	ENOG4108IEH	NADH dehydrogenase subunit g
AKJ08_1075	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AKJ08_1076	ENOG41081QM	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AKJ08_1078	ENOG4105CK1	PTS System
AKJ08_1079	ENOG4105CK1	PTS System
AKJ08_1083	ENOG41067B5	Histone deacetylase superfamily protein
AKJ08_1085	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AKJ08_1090	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AKJ08_1093	ENOG4105KME	endoribonuclease L-psp
AKJ08_1095	ENOG4105EKQ	RNA-directed DNA polymerase
AKJ08_1096	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
AKJ08_1110	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AKJ08_1111	ENOG4105JFG	SpoIID LytB domain protein
AKJ08_1116	ENOG4108EC8	DNA internalization-related competence protein ComEC
AKJ08_1117	ENOG4108VJ1	Transcriptional regulator (CarD family
AKJ08_1118	ENOG4108EM8	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) (By similarity)
AKJ08_1121	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AKJ08_1122	ENOG4107VAM	peptidase, m28
AKJ08_1124	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AKJ08_1129	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AKJ08_1130	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AKJ08_1131	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
AKJ08_1132	ENOG4105VF7	tolerance protein
AKJ08_1143	ENOG4105PW4	Sugar fermentation stimulation protein homolog
AKJ08_1145	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AKJ08_1148	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
AKJ08_1153	ENOG4108KQ5	Integrase catalytic subunit
AKJ08_1165	ENOG4105DZP	Membrane-associated zinc metalloprotease
AKJ08_1169	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AKJ08_1182	ENOG4107QJQ	Mate efflux family protein
AKJ08_1186	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AKJ08_1190	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AKJ08_1198	ENOG4105CSU	acyl-Coa dehydrogenase
AKJ08_1200	ENOG4105BZU	Histidine kinase
AKJ08_1201	ENOG4107AQZ	Membrane
AKJ08_1203	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AKJ08_1204	ENOG4105CHU	acetyl-coa acetyltransferase
AKJ08_1205	ENOG4105D6N	CoA-transferase, subunit a
AKJ08_1206	ENOG4108IIH	CoA-transferase subunit B
AKJ08_1207	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AKJ08_1208	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AKJ08_1211	ENOG4105NQG	DoxX
AKJ08_1213	ENOG4105E18	UPF0276 protein
AKJ08_1216	ENOG4108BAS	reductase
AKJ08_1221	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AKJ08_1229	ENOG4108Z0R	Transferase
AKJ08_1230	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AKJ08_1231	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AKJ08_1233	ENOG4105E39	Enoyl-CoA hydratase
AKJ08_1234	ENOG4105C1G	acyl-Coa dehydrogenase
AKJ08_1236	ENOG4105C1G	acyl-Coa dehydrogenase
AKJ08_1238	ENOG4105D5P	Methylmalonyl-coA mutase
AKJ08_1240	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
AKJ08_1243	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AKJ08_1245	ENOG4105CY0	Metallo-Beta-Lactamase
AKJ08_1250	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AKJ08_1251	ENOG4105C19	ABC transporter
AKJ08_1253	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
AKJ08_1263	ENOG4105DX0	Hemolysin A
AKJ08_1264	ENOG4105ETX	regulatoR
AKJ08_1266	ENOG4108EUD	Lysophospholipase
AKJ08_1269	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AKJ08_1271	ENOG4105EYW	Ion transport protein
AKJ08_1272	ENOG4108IYU	L-aspartate oxidase
AKJ08_1273	ENOG4105E4C	Lytic transglycosylase catalytic
AKJ08_1275	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AKJ08_1276	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
AKJ08_1283	ENOG4105CBT	Fructose-1,6-bisphosphatase
AKJ08_1284	ENOG4105D07	Signal peptide peptidase, SppA
AKJ08_1285	ENOG4105D1F	ATP-binding protein
AKJ08_1288	ENOG4105IJJ	transcriptional regulator, crp fnr family
AKJ08_1293	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AKJ08_1294	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AKJ08_1299	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
AKJ08_1305	ENOG4105YCT	UPF0386 protein
AKJ08_1310	ENOG4105XEZ	This methylase recognizes the double-stranded sequence TCGA, causes specific methylation on A-4 on both strands and protects the DNA from cleavage by the
AKJ08_1313	ENOG4107WZZ	SMC domain protein
AKJ08_1314	ENOG4107QRT	dEAD DEAH box helicase
AKJ08_1315	ENOG4106H3A	restriction
AKJ08_1336	ENOG4105ENH	Sulfatase
AKJ08_1342	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AKJ08_1343	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AKJ08_1345	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AKJ08_1347	ENOG4105DJT	lAO AO transport system ATPase
AKJ08_1348	ENOG4105C1G	acyl-Coa dehydrogenase
AKJ08_1349	ENOG4107QX3	carboxylase
AKJ08_1352	ENOG4105D05	Receptor
AKJ08_1354	ENOG4106QJH	hemin transport protein
AKJ08_1355	ENOG4107R4I	Periplasmic binding protein
AKJ08_1356	ENOG4105EHG	Permease protein
AKJ08_1357	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
AKJ08_1358	ENOG4105E39	Enoyl-CoA hydratase
AKJ08_1359	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AKJ08_1360	ENOG4105BZU	Histidine kinase
AKJ08_1361	ENOG4105BZU	Histidine kinase
AKJ08_1362	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
AKJ08_1363	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AKJ08_1368	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AKJ08_1369	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AKJ08_1370	ENOG4105CQB	FAD linked oxidase domain protein
AKJ08_1371	ENOG4105EUJ	GTP cyclohydrolase i
AKJ08_1372	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
AKJ08_1378	ENOG4105NZG	Ferredoxin
AKJ08_1379	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AKJ08_1383	ENOG4107VGF	ig domain protein group 2 domain protein
AKJ08_1386	ENOG4105K6T	rare lipoprotein A
AKJ08_1391	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AKJ08_1394	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AKJ08_1395	ENOG4105C37	(CBS) domain
AKJ08_1397	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AKJ08_1398	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AKJ08_1399	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AKJ08_1400	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AKJ08_1401	ENOG4105E33	succinate dehydrogenase
AKJ08_1404	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AKJ08_1409	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AKJ08_1411	ENOG4105CXT	aspartate transcarbamylase
AKJ08_1412	ENOG4105DZQ	phospholipase D Transphosphatidylase
AKJ08_1414	ENOG4105C3F	Signal peptidase i
AKJ08_1415	ENOG4105C3F	Signal peptidase i
AKJ08_1416	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AKJ08_1423	ENOG4105CFV	Tetratricopeptide repeat protein
AKJ08_1425	ENOG4105D07	Signal peptide peptidase, SppA
AKJ08_1428	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AKJ08_1430	ENOG4106EEU	Response regulator receiver domain
AKJ08_1434	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
AKJ08_1435	ENOG4105CPK	Glycosyl transferase (Group 1
AKJ08_1437	ENOG4108JUA	Transcriptional regulator
AKJ08_1439	ENOG4108SJC	Membrane
AKJ08_1440	ENOG4108ZX6	Electron transport protein SCO1 SenC
AKJ08_1441	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AKJ08_1443	ENOG41077A9	carbonic anhydrase
AKJ08_1444	ENOG4108JQ7	(ABC) transporter
AKJ08_1446	ENOG4107QHF	type ii secretion system protein e
AKJ08_1447	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AKJ08_1453	ENOG4105SG9	biopolymer transport protein, ExbD
AKJ08_1458	ENOG4105K4I	Scp-like extracellular
AKJ08_1460	ENOG4105VFE	sira family
AKJ08_1462	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AKJ08_1465	ENOG4106TD9	Diguanylate cyclase
AKJ08_1466	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AKJ08_1470	ENOG4105C3Q	Glycosyl transferase, family 2
AKJ08_1480	ENOG41090R7	Ferric uptake
AKJ08_1486	ENOG4105F4G	Membrane
AKJ08_1487	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
AKJ08_1488	ENOG4105CPF	Cell wall formation (By similarity)
AKJ08_1490	ENOG4105D52	delta-aminolevulinic acid dehydratase
AKJ08_1497	ENOG4105C12	Phosphoribosylglycinamide synthetase
AKJ08_1499	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AKJ08_1501	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
AKJ08_1502	ENOG4105CFG	Acts as a chaperone (By similarity)
AKJ08_1516	ENOG4108UPT	UPF0178 protein
AKJ08_1519	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AKJ08_1524	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
AKJ08_1526	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
AKJ08_1539	ENOG4105EMN	RNA polymerase sigma factor
AKJ08_1542	ENOG4105KK4	UPF0060 membrane protein
AKJ08_1543	ENOG4105KVH	Transcriptional regulator
AKJ08_1556	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AKJ08_1559	ENOG4105CHJ	isochorismatase hydrolase
AKJ08_1563	ENOG4108SKZ	Patatin-like phospholipase
AKJ08_1567	ENOG4105CB5	ATP-dependent DNA helicase recG
AKJ08_1569	ENOG4107XZC	Restriction modification system DNA (Specificity
AKJ08_1585	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AKJ08_1586	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AKJ08_1587	ENOG4105CRE	cytochrome C
AKJ08_1589	ENOG4105K63	Thioredoxin
AKJ08_1590	ENOG4105CNI	cell division protein FtsW
AKJ08_1591	ENOG4105CJN	penicillin-binding protein
AKJ08_1594	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
AKJ08_1595	ENOG4105BZU	Histidine kinase
AKJ08_1596	ENOG4108Z03	MAF-like protein
AKJ08_1599	ENOG4105CGH	5'-nucleotidase
AKJ08_1608	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
AKJ08_1609	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
AKJ08_1617	ENOG4105CDY	transcriptional regulatory protein
AKJ08_1621	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AKJ08_1622	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AKJ08_1624	ENOG4107NTM	
AKJ08_1625	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AKJ08_1626	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AKJ08_1628	ENOG4108YZG	isomerase
AKJ08_1630	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AKJ08_1631	ENOG4105CHR	reductase
AKJ08_1632	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AKJ08_1634	ENOG41085D1	50S ribosomal protein L32
AKJ08_1638	ENOG4107RIQ	Sulfate adenylate transferase
AKJ08_1639	ENOG4105K78	MarR family Transcriptional regulator
AKJ08_1640	ENOG4107YR5	Diacylglycerol kinase
AKJ08_1641	ENOG4105C5H	ABC transporter
AKJ08_1646	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AKJ08_1654	ENOG4107ZXI	Rhomboid family
AKJ08_1656	ENOG4105D8X	mechanosensitive ion channel
AKJ08_1657	ENOG4105C34	Pseudouridine synthase
AKJ08_1659	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AKJ08_1660	ENOG4107R21	site-determining protein
AKJ08_1662	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
AKJ08_1663	ENOG4105E4C	Lytic transglycosylase catalytic
AKJ08_1664	ENOG4105BZU	Histidine kinase
AKJ08_1665	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AKJ08_1666	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
AKJ08_1667	ENOG41082RQ	UPF0102 protein
AKJ08_1669	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AKJ08_1672	ENOG4105VB6	UPF0109 protein
AKJ08_1673	ENOG4105K5M	30s ribosomal protein S16
AKJ08_1677	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AKJ08_1683	ENOG4105C34	Pseudouridine synthase
AKJ08_1684	ENOG4105C1V	Peptidase, M16
AKJ08_1687	ENOG4105CA0	peroxidase
AKJ08_1690	ENOG4105TX3	Histidine kinase
AKJ08_1691	ENOG4108UYB	regulatoR
AKJ08_1705	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AKJ08_1708	ENOG4107QHF	type ii secretion system protein e
AKJ08_1709	ENOG4105D7Q	type ii secretion system
AKJ08_1711	ENOG4108VAU	general secretion pathway protein G
AKJ08_1714	ENOG4108WWZ	General secretion pathway protein J
AKJ08_1720	ENOG4105F9F	transposase
AKJ08_1725	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AKJ08_1728	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AKJ08_1730	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AKJ08_1731	ENOG4105C31	Tryptophanyl-tRNA synthetase
AKJ08_1733	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AKJ08_1736	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AKJ08_1738	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AKJ08_1739	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AKJ08_1740	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AKJ08_1741	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
AKJ08_1747	ENOG41072GX	Peptidase M22 Glycoprotease
AKJ08_1748	ENOG4105DZP	Membrane-associated zinc metalloprotease
AKJ08_1750	ENOG4105KNE	Phosphatidate cytidylyltransferase
AKJ08_1751	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AKJ08_1752	ENOG4108PBA	serine threonine protein kinase
AKJ08_1756	ENOG4105CFH	Aspartokinase
AKJ08_1758	ENOG4105CJ1	ABC, transporter
AKJ08_1765	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AKJ08_1766	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AKJ08_1768	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AKJ08_1769	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AKJ08_1771	ENOG4105VW4	glutaredoxin 3
AKJ08_1773	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AKJ08_1778	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AKJ08_1780	ENOG4105IJJ	transcriptional regulator, crp fnr family
AKJ08_1784	ENOG4107RCI	amp-dependent synthetase and ligase
AKJ08_1787	ENOG4105EMN	RNA polymerase sigma factor
AKJ08_1788	ENOG4105CBJ	Metal-dependent enzyme
AKJ08_1789	ENOG41082DI	50s ribosomal protein l31
AKJ08_1792	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AKJ08_1793	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
AKJ08_1794	ENOG4107R19	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AKJ08_1795	ENOG4107RI4	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
AKJ08_1796	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AKJ08_1797	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AKJ08_1799	ENOG4105DR5	peptidase
AKJ08_1801	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
AKJ08_1802	ENOG4105CFG	Acts as a chaperone (By similarity)
AKJ08_1805	ENOG4105CFG	Acts as a chaperone (By similarity)
AKJ08_1808	ENOG4105C26	Dehydrogenase
AKJ08_1809	ENOG4108IJF	Heavy metal efflux pump, CzcA
AKJ08_1817	ENOG4105ECP	epimerase
AKJ08_1819	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AKJ08_1823	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
AKJ08_1824	ENOG4108RWI	nicotinamidase
AKJ08_1828	ENOG4107QI1	Mate efflux family protein
AKJ08_1829	ENOG4107QM5	aconitate hydratase
AKJ08_1836	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AKJ08_1843	ENOG4105CHM	Aminotransferase
AKJ08_1844	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AKJ08_1845	ENOG4105GYT	Protein of unknown function (DUF1009)
AKJ08_1847	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AKJ08_1848	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AKJ08_1854	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
AKJ08_1856	ENOG4105KHC	sulfurtransferase
AKJ08_1857	ENOG4105C0B	DNA polymerase III (alpha subunit)
AKJ08_1858	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AKJ08_1864	ENOG4105C7B	Threonine dehydratase
AKJ08_1878	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AKJ08_1880	ENOG4105CHU	acetyl-coa acetyltransferase
AKJ08_1882	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AKJ08_1884	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AKJ08_1886	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AKJ08_1887	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AKJ08_1888	ENOG4105DGU	Histone deacetylase
AKJ08_1891	ENOG4108JQC	penicillin-binding protein 1A
AKJ08_1892	ENOG4105CEC	DNA methylase N-4 N-6
AKJ08_1893	ENOG4105EI2	Pseudouridine synthase
AKJ08_1896	ENOG4105CYC	Transferase
AKJ08_1903	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AKJ08_1906	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AKJ08_1909	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AKJ08_1910	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
AKJ08_1913	ENOG4105GVR	general secretion pathway protein D
AKJ08_1917	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AKJ08_1918	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
AKJ08_1921	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AKJ08_1922	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AKJ08_1923	ENOG4105CAT	Cytidine monophosphate kinase
AKJ08_1924	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AKJ08_1925	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AKJ08_1927	ENOG4105EEM	helicase
AKJ08_1928	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AKJ08_1929	ENOG4105CUT	histidyl-tRNA synthetase
AKJ08_1930	ENOG4107UP5	Phosphatidylserine decarboxylase
AKJ08_1936	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AKJ08_1938	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AKJ08_1939	ENOG4108ZF3	Phosphatase
AKJ08_1948	ENOG4108ZT0	50S ribosomal protein l17
AKJ08_1951	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AKJ08_1952	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AKJ08_1953	ENOG41067V7	50S ribosomal protein L36
AKJ08_1955	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AKJ08_1956	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AKJ08_1957	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AKJ08_1958	ENOG410856V	50S ribosomal protein L30
AKJ08_1959	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AKJ08_1960	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AKJ08_1961	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AKJ08_1962	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AKJ08_1963	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AKJ08_1964	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AKJ08_1965	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AKJ08_1966	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AKJ08_1967	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AKJ08_1968	ENOG41082SA	50s ribosomal protein l29
AKJ08_1969	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AKJ08_1974	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AKJ08_1975	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AKJ08_1976	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AKJ08_1977	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AKJ08_1978	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AKJ08_1980	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AKJ08_1981	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AKJ08_1989	ENOG4105D82	Glutamate dehydrogenase
AKJ08_1993	ENOG4105C0H	protease
AKJ08_1994	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AKJ08_1999	ENOG4105CI2	imidazolone-5-propionate hydrolase
AKJ08_2003	ENOG4105BZU	Histidine kinase
AKJ08_2004	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AKJ08_2005	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AKJ08_2006	ENOG4105BZU	Histidine kinase
AKJ08_2007	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AKJ08_2008	ENOG4107EPK	O-methyltransferase, family 2
AKJ08_2009	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
AKJ08_2010	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
AKJ08_2011	ENOG4105CGP	Urocanate hydratase
AKJ08_2012	ENOG4108097	ATP-binding protein
AKJ08_2013	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AKJ08_2014	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AKJ08_2015	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
AKJ08_2016	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AKJ08_2017	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AKJ08_2019	ENOG4105C8B	TIGR00159 family
AKJ08_2020	ENOG4105EEI	dihydropteroate synthase
AKJ08_2021	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AKJ08_2022	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AKJ08_2025	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
AKJ08_2026	ENOG4108NNI	Beta-lactamase domain-containing protein
AKJ08_2030	ENOG4108UYI	beta-alanyl-CoA ammonia lyase
AKJ08_2038	ENOG4107CHF	5,6-aminomutase beta subunit
AKJ08_2039	ENOG4105EQ5	D-Lysine 5,6-aminomutase alpha subunit
AKJ08_2041	ENOG4105U0R	haloacid dehalogenase-like hydrolase
AKJ08_2044	ENOG4105FRY	Dehydrogenase
AKJ08_2045	ENOG4107QX8	SPFH domain, Band 7 family protein
AKJ08_2047	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
AKJ08_2054	ENOG4105DCF	alanine dehydrogenase
AKJ08_2055	ENOG4105EMN	RNA polymerase sigma factor
AKJ08_2058	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AKJ08_2061	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
AKJ08_2062	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AKJ08_2064	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AKJ08_2065	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AKJ08_2068	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
AKJ08_2069	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AKJ08_2070	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AKJ08_2071	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AKJ08_2072	ENOG4108VZM	50s ribosomal protein L10
AKJ08_2073	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AKJ08_2074	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AKJ08_2075	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AKJ08_2077	ENOG41084ED	50S ribosomal protein L33
AKJ08_2078	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AKJ08_2079	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AKJ08_2081	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AKJ08_2085	ENOG4105CFG	Acts as a chaperone (By similarity)
AKJ08_2091	ENOG4108UW5	maltose o-acetyltransferase
AKJ08_2104	ENOG4105CPP	Dehydrogenase, E1 component
AKJ08_2106	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AKJ08_2112	ENOG4108YBA	Histidine kinase
AKJ08_2114	ENOG4105C98	muts2 protein
AKJ08_2116	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AKJ08_2118	ENOG4107SWG	transcriptional regulator MERR family
AKJ08_2119	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AKJ08_2120	ENOG4107SUU	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
AKJ08_2122	ENOG4105CPP	Dehydrogenase, E1 component
AKJ08_2123	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AKJ08_2126	ENOG4105C26	Dehydrogenase
AKJ08_2127	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AKJ08_2128	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AKJ08_2129	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AKJ08_2132	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AKJ08_2135	ENOG4107RIQ	Sulfate adenylate transferase
AKJ08_2139	ENOG4105D06	uba thif-type nad fad binding protein
AKJ08_2140	ENOG4105BZU	Histidine kinase
AKJ08_2141	ENOG4105WH1	Two component transcriptional regulator luxr family
AKJ08_2144	ENOG4105C10	Electron transfer flavoprotein
AKJ08_2145	ENOG4105BZJ	Electron transfer flavoprotein
AKJ08_2146	ENOG4105C1G	acyl-Coa dehydrogenase
AKJ08_2147	ENOG4107Z3H	Transcriptional regulator, TetR family
AKJ08_2153	ENOG4105C2X	Arabinose 5-phosphate isomerase
AKJ08_2156	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AKJ08_2157	ENOG4105ERH	Fumarylacetoacetate hydrolase
AKJ08_2158	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AKJ08_2159	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AKJ08_2162	ENOG4108JIC	nucleoside recognition domain protein
AKJ08_2164	ENOG4107QMS	site-determining protein
AKJ08_2167	ENOG4105C34	Pseudouridine synthase
AKJ08_2172	ENOG4107QIV	Cytochrome c biogenesis protein
AKJ08_2174	ENOG4105EMN	RNA polymerase sigma factor
AKJ08_2176	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AKJ08_2177	ENOG4105C25	Primosomal protein n'
AKJ08_2178	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AKJ08_2183	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AKJ08_2184	ENOG4108ZAI	phosphatidylglycerophosphatase a
AKJ08_2185	ENOG4108I62	cina-like protein
AKJ08_2189	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
AKJ08_2191	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AKJ08_2192	ENOG4105C0P	Mg chelatase subunit ChlI
AKJ08_2194	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
AKJ08_2198	ENOG4105CXV	gliding motility protein
AKJ08_2200	ENOG4105ZMH	deoxynucleoside kinase
AKJ08_2202	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AKJ08_2203	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AKJ08_2204	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AKJ08_2205	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AKJ08_2206	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AKJ08_2207	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AKJ08_2208	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AKJ08_2212	ENOG4108ZF3	Phosphatase
AKJ08_2214	ENOG4105EHM	Aminoglycoside phosphotransferase
AKJ08_2215	ENOG4107QJZ	Glycosyl transferase, family 2
AKJ08_2223	ENOG4105C28	cystathionine
AKJ08_2225	ENOG4105DA5	(ABC) transporter
AKJ08_2232	ENOG4105DGA	Diaminopimelate dehydrogenase
AKJ08_2234	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
AKJ08_2235	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AKJ08_2238	ENOG41060WC	Enoyl-CoA hydratase
AKJ08_2239	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
AKJ08_2240	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AKJ08_2241	ENOG4105VEQ	Cold shock protein
AKJ08_2242	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AKJ08_2243	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AKJ08_2247	ENOG4105CPF	Cell wall formation (By similarity)
AKJ08_2248	ENOG4105D4A	Cell wall formation (By similarity)
AKJ08_2250	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AKJ08_2251	ENOG4105CNI	cell division protein FtsW
AKJ08_2252	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AKJ08_2253	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AKJ08_2255	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AKJ08_2256	ENOG4105CJN	penicillin-binding protein
AKJ08_2257	ENOG41068JM	cell division protein, FtsL
AKJ08_2260	ENOG4108V6E	Cell division protein mraZ
AKJ08_2261	ENOG41088YS	Glycosyl transferase (Group 1
AKJ08_2264	ENOG4105CPT	Alpha beta hydrolase
AKJ08_2266	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AKJ08_2268	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AKJ08_2269	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AKJ08_2273	ENOG4105C0A	alcohol dehydrogenase
AKJ08_2274	ENOG4105C5F	glutamine synthetase
AKJ08_2275	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AKJ08_2280	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AKJ08_2282	ENOG4108JQC	penicillin-binding protein 1A
AKJ08_2284	ENOG4105WVQ	Fe-S assembly protein IscX
AKJ08_2285	ENOG4108ZIT	Ferredoxin, 2FE-2S
AKJ08_2286	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
AKJ08_2288	ENOG4108Z4V	iron-sulfur cluster assembly
AKJ08_2289	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
AKJ08_2290	ENOG4105C3J	Cysteine desulfurase
AKJ08_2291	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AKJ08_2292	ENOG4108SPH	protein kinase (EC 2.7.11.1)
AKJ08_2300	ENOG4105BZU	Histidine kinase
AKJ08_2301	ENOG4105C1V	Peptidase, M16
AKJ08_2306	ENOG4105CN1	protease
AKJ08_2309	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AKJ08_2310	ENOG4107Z7S	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AKJ08_2311	ENOG4105K4W	Could be involved in septation (By similarity)
AKJ08_2312	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AKJ08_2315	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AKJ08_2316	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AKJ08_2317	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AKJ08_2318	ENOG4105CDU	Replicative dna helicase
AKJ08_2324	ENOG4108Z86	Glutamine amidotransferase
AKJ08_2325	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AKJ08_2330	ENOG4105CKK	Glycosyl transferase, family 2
AKJ08_2333	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AKJ08_2337	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AKJ08_2338	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AKJ08_2338	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AKJ08_2339	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AKJ08_2340	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AKJ08_2341	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AKJ08_2346	ENOG4105VC4	domain protein
AKJ08_2349	ENOG4108M3P	Membrane
AKJ08_2350	ENOG4108K0D	peptidase, M48
AKJ08_2354	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AKJ08_2367	ENOG4107STQ	Multicopper oxidase
AKJ08_2369	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
AKJ08_2370	ENOG4108QJ2	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase
AKJ08_2372	ENOG4105ER2	Ompa motb domain protein
AKJ08_2376	ENOG4105BZU	Histidine kinase
AKJ08_2377	ENOG4105BZU	Histidine kinase
AKJ08_2383	ENOG4107VGF	ig domain protein group 2 domain protein
AKJ08_2390	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
AKJ08_2394	ENOG4105KJF	protein tyrosine phosphatase
AKJ08_2397	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AKJ08_2398	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AKJ08_2399	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AKJ08_2401	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
AKJ08_2403	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AKJ08_2404	ENOG4105BZU	Histidine kinase
AKJ08_2407	ENOG4105CJW	magnesium transporter
AKJ08_2409	ENOG4107VRP	DNA repair exonuclease
AKJ08_2410	ENOG4105BZM	domain protein
AKJ08_2411	ENOG4105CUY	Mechanosensitive ion channel
AKJ08_2412	ENOG4107QKG	PfaD family
AKJ08_2414	ENOG4105E2T	synthase III
AKJ08_2415	ENOG4108J2P	Alpha beta hydrolase fold
AKJ08_2416	ENOG410680H	amp-dependent synthetase and ligase
AKJ08_2417	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
AKJ08_2420	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
AKJ08_2426	ENOG4105C1J	atp-dependent rna helicase
AKJ08_2427	ENOG4105CGK	Exodeoxyribonuclease III
AKJ08_2430	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
AKJ08_2440	ENOG4105CJ1	ABC, transporter
AKJ08_2442	ENOG4105CHR	reductase
AKJ08_2445	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AKJ08_2446	ENOG4107VGF	ig domain protein group 2 domain protein
AKJ08_2447	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AKJ08_2453	ENOG4105D0M	Protease HtpX homolog
AKJ08_2459	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AKJ08_2460	ENOG4105BZU	Histidine kinase
AKJ08_2462	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
AKJ08_2463	ENOG4105BZU	Histidine kinase
AKJ08_2465	ENOG4105CVA	phosphate
AKJ08_2466	ENOG4105C8U	phosphate abc transporter
AKJ08_2467	ENOG4105E2Z	phosphate ABC transporter (Permease
AKJ08_2468	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AKJ08_2469	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AKJ08_2470	ENOG4105D44	asparaginase
AKJ08_2474	ENOG410642W	LysR family Transcriptional regulator
AKJ08_2481	ENOG4105CV8	reductase
AKJ08_2486	ENOG4105E02	MotA TolQ exbB proton channel
AKJ08_2487	ENOG4105M8F	Biopolymer transport protein exbD tolR
AKJ08_2491	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AKJ08_2520	ENOG4105EST	Metal Dependent Phosphohydrolase
AKJ08_2521	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AKJ08_2522	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AKJ08_2523	ENOG4108J6I	peptidase, M16
AKJ08_2527	ENOG41081HM	2'-5' rna ligase
AKJ08_2528	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AKJ08_2529	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AKJ08_2530	ENOG4105WH1	Two component transcriptional regulator luxr family
AKJ08_2534	ENOG4105C3M	thioredoxin reductase
AKJ08_2535	ENOG4105W5Q	DNA repair protein (RadC
AKJ08_2537	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AKJ08_2541	ENOG4108UUM	single-stranded DNA-binding protein
AKJ08_2542	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
AKJ08_2543	ENOG4108J59	Extracellular solute-binding protein, family 5
AKJ08_2544	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AKJ08_2545	ENOG4107U9T	Pfam:Ribonuclease_BN
AKJ08_2547	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AKJ08_2548	ENOG4105VEQ	Cold shock protein
AKJ08_2549	ENOG4108DG9	Smr protein MutS2
AKJ08_2550	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
AKJ08_2559	ENOG4106HB6	Alpha beta hydrolase
AKJ08_2561	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
AKJ08_2568	ENOG4105C19	ABC transporter
AKJ08_2570	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AKJ08_2582	ENOG4107FW0	short-chain dehydrogenase reductase
AKJ08_2584	ENOG4105DWF	phosphomethylpyrimidine kinase
AKJ08_2585	ENOG4105CHR	reductase
AKJ08_2587	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AKJ08_2588	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AKJ08_2590	ENOG4105K63	Thioredoxin
AKJ08_2595	ENOG4105F0N	pyrophosphate phospho-hydrolase
AKJ08_2604	ENOG4108Q9H	CobQ/CobB/MinD/ParA nucleotide binding domain
AKJ08_2608	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AKJ08_2609	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
AKJ08_2610	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AKJ08_2611	ENOG41080Z8	PHOSPHOCARRIER protein
AKJ08_2612	ENOG4105F3R	pts system mannose fructose sorbose family iid
AKJ08_2614	ENOG4108IQ3	PTS system
AKJ08_2615	ENOG4108EQA	pts system
AKJ08_2616	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AKJ08_2617	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
AKJ08_2618	ENOG4108KXV	response regulator
AKJ08_2619	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
AKJ08_2620	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AKJ08_2621	ENOG4108IUZ	ABC transporter
AKJ08_2624	ENOG4105D1S	lipid A biosynthesis
AKJ08_2625	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
AKJ08_2626	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AKJ08_2628	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
AKJ08_2629	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
AKJ08_2637	ENOG4105CGU	Enoyl-CoA hydratase
AKJ08_2638	ENOG4105KME	endoribonuclease L-psp
AKJ08_2647	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AKJ08_2649	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AKJ08_2651	ENOG4105C1G	acyl-Coa dehydrogenase
AKJ08_2657	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AKJ08_2660	ENOG4105MJ2	Competence protein
AKJ08_2662	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AKJ08_2663	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AKJ08_2664	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
AKJ08_2666	ENOG4105DNZ	Alpha Beta Hydrolase
AKJ08_2668	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AKJ08_2672	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
AKJ08_2673	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AKJ08_2674	ENOG4105EMU	Dehydrogenase
AKJ08_2675	ENOG4105NQG	DoxX
AKJ08_2676	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AKJ08_2679	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AKJ08_2684	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AKJ08_2687	ENOG4105EHG	Permease protein
AKJ08_2688	ENOG4105F8J	Adenylate Guanylate cyclase
AKJ08_2689	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
AKJ08_2691	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
AKJ08_2692	ENOG4105WQ5	TonB family
AKJ08_2694	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AKJ08_2696	ENOG4105F4X	arginine
AKJ08_2700	ENOG4105CAS	nag kinase
AKJ08_2701	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AKJ08_2705	ENOG4105C7Z	Conserved Protein
AKJ08_2708	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AKJ08_2709	ENOG4107RA9	decarboxylase
AKJ08_2711	ENOG4105CFU	surface antigen
AKJ08_2717	ENOG4105E02	MotA TolQ exbB proton channel
AKJ08_2718	ENOG4105SG9	biopolymer transport protein, ExbD
AKJ08_2723	ENOG4105DKQ	ROK family
AKJ08_2729	ENOG4105BZU	Histidine kinase
AKJ08_2730	ENOG4105EFI	regulatoR
AKJ08_2733	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AKJ08_2745	ENOG4105P8F	nudix hydrolase
AKJ08_2746	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AKJ08_2747	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AKJ08_2748	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AKJ08_2749	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AKJ08_2751	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AKJ08_2757	ENOG4105C2M	dna polymerase I
AKJ08_2762	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AKJ08_2763	ENOG4105BZP	glycoside hydrolase 15-related
AKJ08_2765	ENOG4105DFH	Transport of potassium into the cell (By similarity)
AKJ08_2766	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AKJ08_2768	ENOG4105CKI	cobalamin synthesis protein
AKJ08_2770	ENOG4108Z66	YbaK ebsC protein
AKJ08_2771	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
AKJ08_2776	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AKJ08_2782	ENOG4105DUX	Transporter
AKJ08_2783	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AKJ08_2791	ENOG4106FIA	frizzy aggregation protein A
AKJ08_2793	ENOG4108QAF	Methyl-accepting chemotaxis sensory transducer
AKJ08_2794	ENOG4105CBS	Chea signal transduction histidine kinase
AKJ08_2795	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AKJ08_2796	ENOG4105BZU	Histidine kinase
AKJ08_2797	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AKJ08_2799	ENOG4105D8V	Glucose sorbosone dehydrogenase
AKJ08_2801	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AKJ08_2802	ENOG4105F9F	transposase
AKJ08_2805	ENOG4105C5H	ABC transporter
AKJ08_2807	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
AKJ08_2811	ENOG4108Z4T	Peptidase M50
AKJ08_2813	ENOG4105C34	Pseudouridine synthase
AKJ08_2815	ENOG4105E3A	(ABC) transporter
AKJ08_2816	ENOG4105DA5	(ABC) transporter
AKJ08_2819	ENOG4105BZU	Histidine kinase
AKJ08_2821	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
AKJ08_2822	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
AKJ08_2823	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
AKJ08_2824	ENOG4105CQM	Urea amidohydrolase subunit alpha
AKJ08_2825	ENOG4105KI2	Urea amidohydrolase subunit beta
AKJ08_2827	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
AKJ08_2828	ENOG4105XPP	Protein of unknown function (DUF1275)
AKJ08_2836	ENOG4108VCT	Sulfite exporter TauE/SafE
AKJ08_2837	ENOG4107S76	domain protein
AKJ08_2838	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AKJ08_2839	ENOG4106KE4	Dehydrogenase
AKJ08_2846	ENOG4105C5Q	Transcriptional regulator
AKJ08_2847	ENOG4105D3R	alkyl hydroperoxide reductase
AKJ08_2848	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
AKJ08_2851	ENOG4108Y5I	Cyclase dehydrase
AKJ08_2856	ENOG4108ZJT	translation initiation factor, Sui1
AKJ08_2858	ENOG41075H3	AraC family transcriptional regulator
AKJ08_2860	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AKJ08_2861	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
AKJ08_2870	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
AKJ08_2874	ENOG4105ETX	regulatoR
AKJ08_2875	ENOG4106F60	Histidine kinase
AKJ08_2876	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
AKJ08_2877	ENOG4107S1E	Beta-lactamase
AKJ08_2878	ENOG4105DFU	Cell wall formation (By similarity)
AKJ08_2883	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AKJ08_2888	ENOG4105NWN	ApaG protein
AKJ08_2890	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AKJ08_2895	ENOG4105F9F	transposase
AKJ08_2896	ENOG4108QEV	ribosomal RNA large subunit methyltransferase N
AKJ08_2898	ENOG4105EMN	RNA polymerase sigma factor
AKJ08_2899	ENOG4108VX5	3-methyladenine DNA glycosylase
AKJ08_2902	ENOG4105CJR	Integral membrane protein (MviN
AKJ08_2903	ENOG4105DHT	Metal Dependent Phosphohydrolase
AKJ08_2905	ENOG4105JJR	Histidine kinase
AKJ08_2906	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AKJ08_2909	ENOG4105EW9	transcriptional regulator AsnC family
AKJ08_2913	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AKJ08_2914	ENOG4105DUM	transcriptional regulator, lysR family
AKJ08_2917	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AKJ08_2918	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AKJ08_2921	ENOG4107SET	aldo keto reductase
AKJ08_2924	ENOG41080E8	Transcriptional regulator, Spx MgsR family
AKJ08_2926	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
AKJ08_2932	ENOG4105CPQ	Dehydrogenase
AKJ08_2936	ENOG4105C2C	drug resistance transporter, Bcr CflA
AKJ08_2944	ENOG4105CHP	RNA polymerase
AKJ08_2947	ENOG4108Z7F	N-acetyltransferase
AKJ08_2949	ENOG4105NPE	arsR family transcriptional regulator
AKJ08_2952	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
AKJ08_2955	ENOG4105CHR	reductase
AKJ08_2960	ENOG4105CAH	Chromate
AKJ08_2968	ENOG4108Z7F	N-acetyltransferase
AKJ08_2971	ENOG4105C26	Dehydrogenase
AKJ08_2972	ENOG4105CR4	methylisocitrate lyase
AKJ08_2974	ENOG4105RHY	Pfam:UPF0157
AKJ08_2978	ENOG4105BZ1	(ABC) transporter
AKJ08_2979	ENOG4105BZ1	(ABC) transporter
AKJ08_2980	ENOG4107Y2X	deaminase
AKJ08_2987	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AKJ08_2991	ENOG4105EUB	pirin domain protein
AKJ08_2992	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
AKJ08_2997	ENOG4105GRZ	Ycii-related protein
AKJ08_2998	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
AKJ08_3002	ENOG4105EUB	pirin domain protein
AKJ08_3004	ENOG4105EUB	pirin domain protein
AKJ08_3011	ENOG4105C9Q	fumarate hydratase class II
AKJ08_3015	ENOG4105C3M	thioredoxin reductase
AKJ08_3017	ENOG4105C0D	helicase
AKJ08_3025	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AKJ08_3033	ENOG4105C0D	helicase
AKJ08_3037	ENOG4105BZU	Histidine kinase
AKJ08_3040	ENOG4108KPJ	rna polymerase sigma factor
AKJ08_3041	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
AKJ08_3045	ENOG4108KPJ	rna polymerase sigma factor
AKJ08_3051	ENOG4108V1U	phospholipid-binding protein
AKJ08_3052	ENOG4105F9F	transposase
AKJ08_3056	ENOG4105F9F	transposase
AKJ08_3061	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AKJ08_3078	ENOG4105YA8	Transcriptional regulator
AKJ08_3079	ENOG4105CHR	reductase
AKJ08_3081	ENOG4105BZU	Histidine kinase
AKJ08_3082	ENOG4105WH1	Two component transcriptional regulator luxr family
AKJ08_3086	ENOG4105C2I	pirin domain protein
AKJ08_3090	ENOG4108IG5	Transcriptional regulator
AKJ08_3092	ENOG4108UXE	Protein tyrosine phosphatase
AKJ08_3093	ENOG4105D6J	arsenicaL-resistance protein
AKJ08_3095	ENOG4105BZU	Histidine kinase
AKJ08_3096	ENOG4108YYH	Nadph-dependent fmn reductase
AKJ08_3098	ENOG4105CC0	LysR family Transcriptional regulator
AKJ08_3103	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AKJ08_3104	ENOG4105EV9	Alpha Beta Hydrolase
AKJ08_3106	ENOG4105D7N	magnesium and cobalt transport protein CorA
AKJ08_3109	ENOG4108R3E	Dna-3-methyladenine glycosylase i
AKJ08_3116	ENOG41089UC	methyltransferase, type 11
AKJ08_3117	ENOG4107R3N	Filamentation induced by cAMP protein fic
AKJ08_3120	ENOG4105CB5	ATP-dependent DNA helicase recG
AKJ08_3136	ENOG4105MHT	Transcriptional regulator, ARSR family
AKJ08_3137	ENOG41082BM	Transcriptional regulator, arsr family
AKJ08_3139	ENOG4105E7W	lamb ycsf family protein
AKJ08_3140	ENOG4105P4J	Allophanate hydrolase, subunit 1
AKJ08_3141	ENOG4107R7A	Allophanate hydrolase subunit 2
AKJ08_3159	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AKJ08_3161	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AKJ08_3163	ENOG4105CGU	Enoyl-CoA hydratase
AKJ08_3166	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AKJ08_3167	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AKJ08_3168	ENOG4105E2X	shikimate dehydrogenase
AKJ08_3169	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AKJ08_3170	ENOG4105D49	3-dehydroquinate synthase
AKJ08_3171	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AKJ08_3172	ENOG4105DU1	integral membrane protein, terc
AKJ08_3173	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AKJ08_3174	ENOG4105EUB	pirin domain protein
AKJ08_3176	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AKJ08_3180	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AKJ08_3185	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AKJ08_3188	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AKJ08_3190	ENOG4105BZU	Histidine kinase
AKJ08_3194	ENOG4105Z4T	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
AKJ08_3201	ENOG4107SFQ	iron-sulfur binding
AKJ08_3204	ENOG4105CQ7	ATP-dependent helicase
AKJ08_3206	ENOG4105DR4	Methyltransferase
AKJ08_3207	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AKJ08_3208	ENOG4105C0X	amino acid
AKJ08_3209	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
AKJ08_3212	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AKJ08_3213	ENOG4107TEJ	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AKJ08_3214	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AKJ08_3215	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AKJ08_3219	ENOG4105DF6	Fe-S oxidoreductase
AKJ08_3229	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AKJ08_3230	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AKJ08_3234	ENOG4108CXZ	50S ribosomal protein l34
AKJ08_3235	ENOG41084M4	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AKJ08_3236	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AKJ08_3237	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AKJ08_3242	ENOG4105C4W	S-formylglutathione hydrolase
AKJ08_3247	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AKJ08_3249	ENOG4107QJE	Chromosome Partitioning Protein
AKJ08_3250	ENOG4105FA0	parb-like partition protein
AKJ08_3252	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AKJ08_3253	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AKJ08_3254	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AKJ08_3255	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AKJ08_3259	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AKJ08_3264	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AKJ08_3265	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AKJ08_3272	ENOG4105C8J	)-transporter
AKJ08_3273	ENOG4105CKU	formyltetrahydrofolate synthetase
AKJ08_3274	ENOG4105HMI	Membrane
AKJ08_3276	ENOG4105DUM	transcriptional regulator, lysR family
AKJ08_3277	ENOG4105DUM	transcriptional regulator, lysR family
AKJ08_3278	ENOG41080XP	Cbs domain
AKJ08_3279	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
AKJ08_3281	ENOG4108YYC	ycei family
AKJ08_3282	ENOG4105JQN	Transcriptional regulator
AKJ08_3285	ENOG4108W6C	Dehydrogenase
AKJ08_3288	ENOG4105YB8	TM2 domain containing protein
AKJ08_3289	ENOG4105C9K	Endothelin-converting enzyme 1
AKJ08_3292	ENOG4108V0P	LemA family
AKJ08_3296	ENOG410812K	response regulator receiver protein
AKJ08_3297	ENOG4105BZU	Histidine kinase
AKJ08_3305	ENOG4105CUX	Signal transduction histidine kinase
AKJ08_3309	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
AKJ08_3311	ENOG4108KJP	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AKJ08_3312	ENOG4105C3G	gtp-binding protein
AKJ08_3314	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AKJ08_3315	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AKJ08_3316	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AKJ08_3317	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
AKJ08_3318	ENOG4105DGW	oligopeptidase A
AKJ08_3322	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AKJ08_3324	ENOG4105D7W	serine acetyltransferase
AKJ08_3325	ENOG4105C6T	cysteine synthase
AKJ08_3333	ENOG4105FR1	rard protein
AKJ08_3334	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AKJ08_3339	ENOG4108JA2	transcriptioN-repair coupling factor
AKJ08_3340	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AKJ08_3341	ENOG4105CFG	Acts as a chaperone (By similarity)
AKJ08_3342	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
AKJ08_3343	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AKJ08_3356	ENOG4105R8A	Heat shock protein
AKJ08_3357	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AKJ08_3362	ENOG4105CPC	Aldo Keto reductase
AKJ08_3364	ENOG4105CIS	alcohol dehydrogenase
AKJ08_3365	ENOG4105EUB	pirin domain protein
AKJ08_3367	ENOG4108Z18	K06886 hemoglobin
AKJ08_3369	ENOG4105C59	p-type ATPase
AKJ08_3371	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
AKJ08_3373	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
AKJ08_3376	ENOG4105D4P	Coproporphyrinogen iii oxidase
AKJ08_3379	ENOG4107W9T	flagellar hook-associated
AKJ08_3380	ENOG4105I03	Flagellin
AKJ08_3386	ENOG4105DR5	peptidase
AKJ08_3390	ENOG4105CGA	flagellar basal-body rod protein FlgG
AKJ08_3391	ENOG4105KTQ	flagellar basal-body rod protein
AKJ08_3393	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AKJ08_3395	ENOG4105FZW	flagellar biosynthesis regulator FlhF
AKJ08_3396	ENOG4105D7B	Flagellar biosynthesis protein flha
AKJ08_3397	ENOG4105D00	flagellar biosynthetic protein flhB
AKJ08_3398	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
AKJ08_3399	ENOG4105VS8	Flagellar biosynthetic protein fliq
AKJ08_3400	ENOG4105CN7	Flagellar biosynthetic protein FliP
AKJ08_3402	ENOG4105DD5	Flagellar motor switch protein
AKJ08_3403	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AKJ08_3405	ENOG4106VK6	Flagellar motor protein
AKJ08_3408	ENOG4105BZE	flagellar hook protein, FlgE
AKJ08_3409	ENOG410822I	Flagellar hook capping protein
AKJ08_3412	ENOG4108JIR	Flagellum-specific ATP synthase
AKJ08_3414	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AKJ08_3415	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
AKJ08_3416	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
AKJ08_3417	ENOG4108ZC9	flagellar basal-body rod protein flgc
AKJ08_3418	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
AKJ08_3420	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AKJ08_3421	ENOG4105BZU	Histidine kinase
AKJ08_3426	ENOG4105DVT	helicase
AKJ08_3428	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AKJ08_3429	ENOG4105CXV	gliding motility protein
AKJ08_3430	ENOG4105BZU	Histidine kinase
AKJ08_3431	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AKJ08_3432	ENOG4105C8Q	Methyl-accepting chemotaxis
AKJ08_3434	ENOG4105CBS	Chea signal transduction histidine kinase
AKJ08_3435	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
AKJ08_3436	ENOG4105C8M	UPF0272 protein
AKJ08_3437	ENOG4105BZU	Histidine kinase
AKJ08_3442	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AKJ08_3445	ENOG4105ERH	Fumarylacetoacetate hydrolase
AKJ08_3446	ENOG4108RXX	maleylacetoacetate isomerase
AKJ08_3447	ENOG4105F1J	Homogentisate 1,2-dioxygenase
AKJ08_3448	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
AKJ08_3463	ENOG4108IV0	ABC, transporter
AKJ08_3464	ENOG4105C0Z	ABC transporter
AKJ08_3465	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
AKJ08_3466	ENOG4105C32	Amino acid ABC transporter (Permease)
AKJ08_3467	ENOG4105CP9	extracellular ligand-binding receptor
AKJ08_3469	ENOG4105D17	glycoside hydrolase, family 3 domain protein
AKJ08_3470	ENOG4105BZU	Histidine kinase
AKJ08_3473	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AKJ08_3476	ENOG4105EMN	RNA polymerase sigma factor
AKJ08_3484	ENOG4105ESV	Glycosyl transferase, family 4
AKJ08_3487	ENOG4106CD9	glycosyl transferase group 1
AKJ08_3492	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
AKJ08_3506	ENOG4107Y80	Major Facilitator superfamily
AKJ08_3508	ENOG4105BZU	Histidine kinase
AKJ08_3509	ENOG4105BZU	Histidine kinase
AKJ08_3510	ENOG4105BZU	Histidine kinase
AKJ08_3518	ENOG4107RH8	nuclease SbcCD subunit D
AKJ08_3519	ENOG4105EYH	Exonuclease
AKJ08_3520	ENOG4108FN7	Aldo keto reductase
AKJ08_3524	ENOG4105BZU	Histidine kinase
AKJ08_3525	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AKJ08_3537	ENOG4105DEN	Luciferase family
AKJ08_3538	ENOG4108YZN	class I peptide chain release factor
AKJ08_3545	ENOG4105CA0	peroxidase
AKJ08_3546	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AKJ08_3559	ENOG4108UVJ	appr-1-p processing domain protein
AKJ08_3562	ENOG4108VK3	Cupin 2 Conserved Barrel Domain Protein
AKJ08_3564	ENOG4105E0X	reductase
AKJ08_3567	ENOG4107T6F	Xaa-Pro aminopeptidase
AKJ08_3569	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AKJ08_3571	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AKJ08_3576	ENOG4105BZU	Histidine kinase
AKJ08_3578	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AKJ08_3580	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AKJ08_3581	ENOG4105BZS	acriflavin resistance protein
AKJ08_3582	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AKJ08_3588	ENOG4105G6Z	alkaline phosphatase
AKJ08_3589	ENOG4105G6Z	alkaline phosphatase
AKJ08_3603	ENOG4105CF1	Alkylated DNA repair protein
AKJ08_3605	ENOG4105EUB	pirin domain protein
AKJ08_3606	ENOG4105WCN	acetyltransferase
AKJ08_3614	ENOG4105CEY	Amp-dependent synthetase and ligase
AKJ08_3624	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
AKJ08_3630	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AKJ08_3632	ENOG4105CYW	agmatinase
AKJ08_3633	ENOG4105CD3	dihydroorotase
AKJ08_3634	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AKJ08_3647	ENOG4105DQ4	alcohol dehydrogenase
AKJ08_3649	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AKJ08_3650	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AKJ08_3653	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AKJ08_3656	ENOG4105F9F	transposase
AKJ08_3660	ENOG4107RDB	Major Facilitator
AKJ08_3662	ENOG4105CD3	dihydroorotase
AKJ08_3665	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AKJ08_3666	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AKJ08_3667	ENOG4108K3A	Glutathione S-transferase
AKJ08_3668	ENOG4105C5H	ABC transporter
AKJ08_3669	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AKJ08_3672	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
AKJ08_3673	ENOG4105C0H	protease
AKJ08_3676	ENOG4105KJJ	Uncharacterized ACR, COG1993
AKJ08_3677	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
AKJ08_3678	ENOG4105CG3	alpha amylase, catalytic region
AKJ08_3679	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AKJ08_3682	ENOG4107SJW	iron permease, FTR1
AKJ08_3691	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AKJ08_3692	ENOG4108TQ9	Histidine kinase
AKJ08_3703	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AKJ08_3704	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AKJ08_3705	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AKJ08_3709	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AKJ08_3710	ENOG4105K46	50S ribosomal protein l27
AKJ08_3711	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AKJ08_3714	ENOG4105ECY	inositol monophosphatase
AKJ08_3715	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AKJ08_3716	ENOG4108VPT	UPF0234 protein
AKJ08_3717	ENOG4105CN5	Metallo-Beta-Lactamase
AKJ08_3723	ENOG4105DN3	alpha-2-macroglobulin domain protein