locus-tag	class	description
wcw_0009	ENOG410600T	transposase
wcw_0013	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
wcw_0015	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
wcw_0016	ENOG4105DJ9	glucan biosynthesis protein
wcw_0017	ENOG4105CPF	Cell wall formation (By similarity)
wcw_0020	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
wcw_0021	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
wcw_0022	ENOG4105C83	adenylosuccinate lyase
wcw_0023	ENOG4106MFV	virulence plasmid
wcw_0024	ENOG4105C2U	cobyrinic Acid a,c-diamide synthase
wcw_0025	ENOG4105C22	threonyL-tRNA synthetase
wcw_0031	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
wcw_0032	ENOG4105DSY	exodeoxyribonuclease V, gamma
wcw_0033	ENOG4107QKA	exodeoxyribonuclease V beta
wcw_0034	ENOG4107QYX	exodeoxyribonuclease v alpha
wcw_0038	ENOG4105D52	delta-aminolevulinic acid dehydratase
wcw_0039	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
wcw_0049	ENOG4105D5G	Transposase
wcw_0056	ENOG4105EAC	phosphoserine phosphatase
wcw_0057	ENOG4108JQ1	Dehydrogenase
wcw_0061	ENOG4105DAY	polysaccharide export protein
wcw_0069	ENOG4105FAW	cDP-glucose 4,6-dehydratase
wcw_0071	ENOG4105E0U	tyrosine-specific transport protein
wcw_0073	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
wcw_0074	ENOG4105W8H	transhydrogenase (subunit alpha
wcw_0075	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
wcw_0076	ENOG4108IQE	Amp-dependent synthetase and ligase
wcw_0078	ENOG4105CGF	Aromatic amino acid aminotransferase
wcw_0081	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
wcw_0082	ENOG4107U85	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
wcw_0088	ENOG4105C9B	Cysteine desulfurase
wcw_0089	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
wcw_0092	ENOG4105VS8	Flagellar biosynthetic protein fliq
wcw_0099	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
wcw_0100	ENOG4107QN2	dihydrolipoyl dehydrogenase
wcw_0106	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
wcw_0108	ENOG4105DJ4	phosphatidylserine decarboxylase
wcw_0109	ENOG4105F8V	Hydrolase, tatD family
wcw_0112	ENOG4105C0A	alcohol dehydrogenase
wcw_0120	ENOG4107RB8	Involved in the TonB-independent uptake of proteins (By similarity)
wcw_0122	ENOG4105KCK	Peptidoglycan-associated lipoprotein
wcw_0123	ENOG4107X35	defense response to bacterium
wcw_0124	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
wcw_0127	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
wcw_0128	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
wcw_0133	ENOG4106H78	methyltransferase
wcw_0147	ENOG4105CHR	reductase
wcw_0152	ENOG4107RQ5	Methylates ribosomal protein L11 (By similarity)
wcw_0159	ENOG4105D1H	recombination factor protein RarA
wcw_0162	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
wcw_0166	ENOG4105CK7	Sodium proline symporter
wcw_0167	ENOG4105J5G	Transferase hexapeptide repeat containing protein
wcw_0170	ENOG4105CI3	gtp-binding protein typa
wcw_0171	ENOG4105CN5	Metallo-Beta-Lactamase
wcw_0172	ENOG4105BZM	domain protein
wcw_0173	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
wcw_0188	ENOG4108P8V	Thymidylate synthase complementing protein ThyX
wcw_0189	ENOG4105E0U	tyrosine-specific transport protein
wcw_0190	ENOG4105E0U	tyrosine-specific transport protein
wcw_0191	ENOG4105C31	Tryptophanyl-tRNA synthetase
wcw_0192	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
wcw_0196	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
wcw_0197	ENOG4105KA0	thioesterase Superfamily protein
wcw_0200	ENOG4109015	Biopolymer transport protein exbD tolR
wcw_0203	ENOG4106AP9	histone H1-like protein
wcw_0204	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
wcw_0205	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
wcw_0206	ENOG41084RR	Preprotein translocase subunit YajC
wcw_0207	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
wcw_0212	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
wcw_0213	ENOG4105DN9	Na H antiporter
wcw_0214	ENOG4105E7T	carrier protein
wcw_0215	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
wcw_0216	ENOG4107RKJ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
wcw_0220	ENOG410600T	transposase
wcw_0227	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
wcw_0228	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
wcw_0233	ENOG4108JA2	transcriptioN-repair coupling factor
wcw_0234	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
wcw_0237	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
wcw_0238	ENOG4105CHH	sulfate transporter
wcw_0239	ENOG4105CV1	Transketolase (EC 2.2.1.1)
wcw_0240	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
wcw_0241	ENOG4105C1Q	protoporphyrinogen oxidase
wcw_0242	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
wcw_0245	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
wcw_0246	ENOG4105DM4	PTS System
wcw_0247	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
wcw_0248	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
wcw_0249	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
wcw_0250	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
wcw_0251	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
wcw_0252	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
wcw_0263	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
wcw_0264	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
wcw_0265	ENOG4108JEM	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
wcw_0266	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
wcw_0267	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
wcw_0268	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
wcw_0269	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
wcw_0270	ENOG4107UK7	na( )-translocating NADH-quinone reductase subunit b
wcw_0275	ENOG4105FJR	Lmbe family
wcw_0276	ENOG4105CPK	Glycosyl transferase (Group 1
wcw_0277	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
wcw_0282	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
wcw_0285	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
wcw_0287	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
wcw_0290	ENOG4105CJ3	phosphate transporter
wcw_0291	ENOG4107IX6	phosphate transport regulator
wcw_0292	ENOG4105C3U	ABC transporter
wcw_0293	ENOG4108JQ7	(ABC) transporter
wcw_0296	ENOG4105FE9	pseudouridine synthase
wcw_0297	ENOG4107XMU	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
wcw_0299	ENOG4107RIU	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity)
wcw_0300	ENOG4105K63	Thioredoxin
wcw_0301	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
wcw_0302	ENOG4105CNI	cell division protein FtsW
wcw_0305	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
wcw_0306	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
wcw_0307	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
wcw_0308	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
wcw_0312	ENOG4105CAT	Cytidine monophosphate kinase
wcw_0314	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
wcw_0315	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
wcw_0316	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
wcw_0319	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
wcw_0320	ENOG4105EE5	Membrane protein terC
wcw_0321	ENOG41081M5	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
wcw_0322	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
wcw_0323	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
wcw_0330	ENOG4107YDW	inorganic pyrophosphatase EC 3.6.1.1
wcw_0333	ENOG4105CEY	Amp-dependent synthetase and ligase
wcw_0336	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
wcw_0337	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
wcw_0339	ENOG4105CD3	dihydroorotase
wcw_0340	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
wcw_0341	ENOG4105CXT	aspartate transcarbamylase
wcw_0344	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
wcw_0350	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
wcw_0352	ENOG4105CJN	penicillin-binding protein
wcw_0353	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
wcw_0356	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
wcw_0357	ENOG4105DZP	Membrane-associated zinc metalloprotease
wcw_0361	ENOG4105BZ1	(ABC) transporter
wcw_0362	ENOG4105BZ1	(ABC) transporter
wcw_0365	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
wcw_0368	ENOG4105K5B	UPF0225 protein
wcw_0373	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
wcw_0374	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
wcw_0376	ENOG4107XAV	metallophosphoesterase
wcw_0385	ENOG4105CDY	transcriptional regulatory protein
wcw_0386	ENOG4105CRQ	synthase (Component I)
wcw_0394	ENOG4107R1M	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
wcw_0398	ENOG4107VK2	coenzyme PQQ biosynthesis protein PqqF
wcw_0401	ENOG4105C03	ribonuclease
wcw_0404	ENOG41086AQ	50s ribosomal protein l32
wcw_0405	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
wcw_0410	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
wcw_0411	ENOG4105CKK	Glycosyl transferase, family 2
wcw_0413	ENOG4105DJ0	Poly(A) Polymerase
wcw_0415	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
wcw_0416	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
wcw_0417	ENOG4105E0U	tyrosine-specific transport protein
wcw_0420	ENOG4107RH8	nuclease SbcCD subunit D
wcw_0421	ENOG4105EYH	Exonuclease
wcw_0423	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
wcw_0424	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
wcw_0425	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
wcw_0430	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
wcw_0432	ENOG4105C0H	protease
wcw_0433	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
wcw_0435	ENOG4105CK2	sodium dicarboxylate symporter
wcw_0437	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
wcw_0439	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
wcw_0442	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
wcw_0443	ENOG4105BZP	glycoside hydrolase 15-related
wcw_0447	ENOG4107QX3	carboxylase
wcw_0450	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
wcw_0451	ENOG4105C8F	Beta-lactamase domain protein
wcw_0462	ENOG4105D5P	Methylmalonyl-coA mutase
wcw_0464	ENOG4107SUU	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
wcw_0465	ENOG4105CPP	Dehydrogenase, E1 component
wcw_0467	ENOG4105K78	MarR family Transcriptional regulator
wcw_0468	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
wcw_0473	ENOG4105DR4	Methyltransferase
wcw_0475	ENOG410600T	transposase
wcw_0479	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
wcw_0483	ENOG4105D5G	Transposase
wcw_0485	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
wcw_0487	ENOG4105CCU	oxidase (Subunit III)
wcw_0488	ENOG4105BZ9	Cytochrome C oxidase, subunit I
wcw_0489	ENOG4105E2S	oxidase) subunit II
wcw_0492	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
wcw_0493	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
wcw_0498	ENOG410600T	transposase
wcw_0500	ENOG4108ZED	Transmembrane domain of unknown function (DUF3566)
wcw_0503	ENOG4108IAB	Phoh family
wcw_0504	ENOG4105C1J	atp-dependent rna helicase
wcw_0507	ENOG4105CBX	hi0933 family
wcw_0509	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
wcw_0511	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
wcw_0513	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
wcw_0514	ENOG4105DQ4	alcohol dehydrogenase
wcw_0515	ENOG4105NQN	cytochrome C
wcw_0517	ENOG4105CPN	adenine deaminase
wcw_0518	ENOG4105D7A	ATP-binding protein
wcw_0519	ENOG4107SET	aldo keto reductase
wcw_0527	ENOG4105DFS	Conserved Protein
wcw_0530	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
wcw_0532	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
wcw_0533	ENOG4105C3F	Signal peptidase i
wcw_0535	ENOG4105BZW	Glycerate kinase
wcw_0536	ENOG4105DAP	Nicotinate phosphoribosyltransferase
wcw_0538	ENOG4108RWI	nicotinamidase
wcw_0540	ENOG4105VZ9	UPF0235 protein
wcw_0542	ENOG4105CHR	reductase
wcw_0547	ENOG410600T	transposase
wcw_0556	ENOG4105C5H	ABC transporter
wcw_0557	ENOG4105CR8	Transcriptional regulator
wcw_0559	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
wcw_0560	ENOG4105C37	(CBS) domain
wcw_0563	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
wcw_0572	ENOG4108KBP	metal-dependent protein hydrolase
wcw_0573	ENOG41083IP	HIT family
wcw_0576	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
wcw_0579	ENOG4105DC7	peptidase M24
wcw_0580	ENOG4105E0U	tyrosine-specific transport protein
wcw_0582	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
wcw_0584	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
wcw_0587	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
wcw_0588	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
wcw_0589	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
wcw_0590	ENOG410823K	50S ribosomal protein L10
wcw_0591	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
wcw_0592	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
wcw_0593	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
wcw_0596	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
wcw_0603	ENOG4108ZE2	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
wcw_0604	ENOG4108XKX	Protein of unknown function (DUF2764)
wcw_0605	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
wcw_0606	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
wcw_0607	ENOG4108WBK	V-type ATP synthase subunit D
wcw_0608	ENOG4107VJ3	V-type ATP synthase subunit I (EC 3.6.3.14)
wcw_0610	ENOG4105C9Q	fumarate hydratase class II
wcw_0613	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
wcw_0615	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
wcw_0617	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
wcw_0626	ENOG4105CMM	transposase
wcw_0639	ENOG4105CHR	reductase
wcw_0642	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
wcw_0645	ENOG4105KME	endoribonuclease L-psp
wcw_0647	ENOG4105DBI	uridine monophosphokinase
wcw_0650	ENOG4105EIE	fructose-bisphosphate aldolase
wcw_0653	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
wcw_0655	ENOG4105CH6	catalase
wcw_0678	ENOG4105CTD	carboxy-peptidase
wcw_0679	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
wcw_0684	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
wcw_0685	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
wcw_0687	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
wcw_0688	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
wcw_0690	ENOG4108Z6B	deaminase
wcw_0694	ENOG4105NRA	50s ribosomal protein l31 type b
wcw_0695	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
wcw_0696	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
wcw_0698	ENOG4105K5M	30s ribosomal protein S16
wcw_0699	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
wcw_0700	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
wcw_0701	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
wcw_0705	ENOG4105DSJ	YicC domain protein
wcw_0706	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
wcw_0709	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
wcw_0710	ENOG4105KDC	50s ribosomal protein l28
wcw_0715	ENOG4105VFU	Rna-binding protein
wcw_0718	ENOG4107QP3	malate synthase g
wcw_0721	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
wcw_0722	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
wcw_0723	ENOG41074B2	UPF0747 protein
wcw_0725	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
wcw_0726	ENOG4105C89	phosphohexose isomerase
wcw_0728	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
wcw_0731	ENOG4108R6K	riboflavin synthase, subunit alpha
wcw_0735	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
wcw_0737	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
wcw_0738	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
wcw_0739	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
wcw_0742	ENOG4105ECP	epimerase
wcw_0744	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
wcw_0752	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
wcw_0754	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
wcw_0757	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
wcw_0758	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
wcw_0759	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
wcw_0762	ENOG4105CHC	glucokinase (EC 2.7.1.2)
wcw_0764	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
wcw_0765	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
wcw_0766	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
wcw_0768	ENOG41066YJ	Beta-lactamase
wcw_0769	ENOG4105M08	Membrane
wcw_0771	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
wcw_0772	ENOG4105C7H	Helicase, RecD TraA family
wcw_0774	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
wcw_0781	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
wcw_0783	ENOG4105C8B	TIGR00159 family
wcw_0784	ENOG4105EEI	dihydropteroate synthase
wcw_0785	ENOG4105C4M	(Ubiquinol oxidase) subunit I
wcw_0786	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
wcw_0787	ENOG4105F9F	transposase
wcw_0790	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
wcw_0792	ENOG4105C0B	DNA polymerase III (alpha subunit)
wcw_0793	ENOG4105D4A	Cell wall formation (By similarity)
wcw_0794	ENOG41083G4	Involved in the transcription termination process (By similarity)
wcw_0797	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
wcw_0799	ENOG4105C7N	Xanthine uracil vitamin C permease
wcw_0803	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
wcw_0804	ENOG4106E9S	50S ribosomal protein L36
wcw_0805	ENOG4105VG0	50S ribosomal protein l34
wcw_0807	ENOG4105MH8	Thioredoxin disulfide isomerase
wcw_0809	ENOG4105BZG	amino acid carrier protein
wcw_0811	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
wcw_0814	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
wcw_0815	ENOG4108227	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
wcw_0816	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
wcw_0817	ENOG4105JDP	Binds together with S18 to 16S ribosomal RNA (By similarity)
wcw_0818	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
wcw_0819	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
wcw_0820	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
wcw_0821	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
wcw_0828	ENOG4105CQB	FAD linked oxidase domain protein
wcw_0829	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
wcw_0830	ENOG4105C26	Dehydrogenase
wcw_0840	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
wcw_0842	ENOG4108WBT	adenosyltransferase
wcw_0844	ENOG4107S1W	4-alpha-glucanotransferase
wcw_0851	ENOG4105C3G	gtp-binding protein
wcw_0855	ENOG4105DTN	riboflavin biosynthesis protein ribF
wcw_0856	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
wcw_0857	ENOG41080JB	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
wcw_0858	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
wcw_0859	ENOG4105CHV	Transcription elongation factor NusA
wcw_0860	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
wcw_0862	ENOG4105CFH	Aspartokinase
wcw_0864	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
wcw_0866	ENOG4105DJV	ribulose-phosphate 3-epimerase
wcw_0867	ENOG4108S1P	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
wcw_0868	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
wcw_0869	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
wcw_0873	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
wcw_0874	ENOG4108JYZ	YitT family
wcw_0878	ENOG4107YFT	Nadph-dependent fmn reductase
wcw_0879	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
wcw_0881	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
wcw_0882	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
wcw_0883	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
wcw_0887	ENOG4108VQJ	O-methyltransferase
wcw_0888	ENOG4105E0X	reductase
wcw_0889	ENOG4105CAY	ferredoxin--nadp reductase
wcw_0892	ENOG4107QM5	aconitate hydratase
wcw_0898	ENOG4107104	thymidine kinase
wcw_0899	ENOG4105C5H	ABC transporter
wcw_0901	ENOG4105DJ0	Poly(A) Polymerase
wcw_0902	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
wcw_0903	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
wcw_0904	ENOG4105DSF	transport protein
wcw_0910	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
wcw_0913	ENOG4105C22	threonyL-tRNA synthetase
wcw_0914	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
wcw_0915	ENOG4107MK0	50s ribosomal protein l35
wcw_0916	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
wcw_0917	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
wcw_0918	ENOG4105EI2	Pseudouridine synthase
wcw_0919	ENOG4105D16	lipopolysaccharide heptosyltransferase i
wcw_0920	ENOG4105C9U	ATP-dependent DNA helicase RecQ
wcw_0921	ENOG4107RUE	extracellular solute-binding protein family 1
wcw_0922	ENOG4105D38	putrescine abc transporter
wcw_0923	ENOG4105F38	ABC transporter, permease
wcw_0924	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
wcw_0925	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
wcw_0926	ENOG4108DNC	Involved in acetate metabolism (By similarity)
wcw_0934	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
wcw_0935	ENOG4105CAQ	asparagine synthetase
wcw_0944	ENOG410902C	phosphohistidine phosphatase, SixA
wcw_0945	ENOG4105CHR	reductase
wcw_0947	ENOG4108ZF3	Phosphatase
wcw_0948	ENOG4105C3J	Cysteine desulfurase
wcw_0950	ENOG4108JU5	Magnesium and cobalt efflux protein
wcw_0957	ENOG4105C7Z	Conserved Protein
wcw_0959	ENOG4105CJW	magnesium transporter
wcw_0965	ENOG4105C8J	)-transporter
wcw_0966	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
wcw_0968	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
wcw_0971	ENOG4108UUM	single-stranded DNA-binding protein
wcw_0972	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
wcw_0973	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
wcw_0976	ENOG4105D2T	synthase
wcw_0981	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
wcw_0983	ENOG4105CSA	Coproporphyrinogen iii oxidase
wcw_0985	ENOG4105BZU	Histidine kinase
wcw_0987	ENOG4105D8X	mechanosensitive ion channel
wcw_0988	ENOG4105C3M	thioredoxin reductase
wcw_0990	ENOG4105CRE	cytochrome C
wcw_0991	ENOG4108NIU	serine-type peptidase activity
wcw_0996	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
wcw_0997	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
wcw_0998	ENOG4105C7S	Dehydrogenase
wcw_0999	ENOG4107QN2	dihydrolipoyl dehydrogenase
wcw_1000	ENOG4105V5Z	Iron-sulfur cluster assembly accessory protein
wcw_1003	ENOG4107QZC	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
wcw_1006	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
wcw_1007	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
wcw_1008	ENOG4105E6M	Sulphatase-modifying factor protein
wcw_1011	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
wcw_1012	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
wcw_1014	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
wcw_1015	ENOG4107QRG	dna polymerase iii
wcw_1016	ENOG4105E4F	Isochorismate synthase
wcw_1017	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
wcw_1025	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
wcw_1027	ENOG4108IPT	Naphthoate synthase
wcw_1028	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
wcw_1033	ENOG4107QNM	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
wcw_1035	ENOG4108NVI	
wcw_1036	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
wcw_1037	ENOG4105C37	(CBS) domain
wcw_1038	ENOG4107Z9E	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
wcw_1047	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
wcw_1048	ENOG4105C8T	Leucyl-tRNA synthetase
wcw_1050	ENOG4105E18	UPF0276 protein
wcw_1054	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
wcw_1056	ENOG41088SP	formiminoglutamate hydrolase
wcw_1057	ENOG4105CI2	imidazolone-5-propionate hydrolase
wcw_1058	ENOG4105CGP	Urocanate hydratase
wcw_1059	ENOG4105C84	Histidine ammonia-lyase
wcw_1062	ENOG4108V1U	phospholipid-binding protein
wcw_1063	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
wcw_1064	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
wcw_1068	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
wcw_1073	ENOG4105EGS	Mechanosensitive ion channel
wcw_1074	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
wcw_1079	ENOG4105EJQ	L-serine dehydratase
wcw_1081	ENOG4107RJF	diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90)
wcw_1084	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
wcw_1085	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
wcw_1087	ENOG4107S2Z	UPF0761 membrane protein
wcw_1091	ENOG410600T	transposase
wcw_1094	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
wcw_1098	ENOG4108IJ8	ABC transporter
wcw_1099	ENOG4105E90	ABC transporter
wcw_1100	ENOG4108V0P	LemA family
wcw_1101	ENOG4105D0M	Protease HtpX homolog
wcw_1106	ENOG41076HS	cation diffusion facilitator family transporter
wcw_1107	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
wcw_1108	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
wcw_1109	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
wcw_1112	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
wcw_1115	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
wcw_1116	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
wcw_1122	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
wcw_1123	ENOG410842R	atp synthase
wcw_1124	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
wcw_1125	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
wcw_1126	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
wcw_1127	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
wcw_1128	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
wcw_1129	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
wcw_1132	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
wcw_1134	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
wcw_1135	ENOG4105FE9	pseudouridine synthase
wcw_1136	ENOG4105BZU	Histidine kinase
wcw_1137	ENOG4105BZU	Histidine kinase
wcw_1138	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
wcw_1140	ENOG4105D60	lipoprotein releasing system transmembrane protein
wcw_1141	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
wcw_1145	ENOG4105C28	cystathionine
wcw_1147	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
wcw_1148	ENOG4105CPQ	Dehydrogenase
wcw_1153	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
wcw_1155	ENOG4105CP7	Triose-phosphate isomerase
wcw_1156	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
wcw_1157	ENOG4108877	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
wcw_1158	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
wcw_1163	ENOG4105DXX	methyltransferase
wcw_1165	ENOG4108Z03	MAF-like protein
wcw_1168	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
wcw_1169	ENOG4105CTB	Polyprenyl synthetase
wcw_1173	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
wcw_1174	ENOG4105CJ2	(LipO)protein
wcw_1179	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
wcw_1180	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
wcw_1181	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
wcw_1182	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
wcw_1184	ENOG4105CTP	PilT protein domain protein
wcw_1185	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
wcw_1186	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
wcw_1187	ENOG4105CHR	reductase
wcw_1188	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
wcw_1189	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
wcw_1190	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
wcw_1193	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
wcw_1202	ENOG4105CPP	Dehydrogenase, E1 component
wcw_1205	ENOG4105CK2	sodium dicarboxylate symporter
wcw_1209	ENOG4105DFA	alanine racemase domain protein
wcw_1211	ENOG4105DI5	UPF0365 protein
wcw_1212	ENOG4105F7J	membrane-bound serine protease
wcw_1213	ENOG4105F7J	membrane-bound serine protease
wcw_1214	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
wcw_1215	ENOG4105CFU	surface antigen
wcw_1218	ENOG4105CAQ	asparagine synthetase
wcw_1220	ENOG4105CY3	ABC transporter, permease
wcw_1223	ENOG4108UJU	UPF0301 protein
wcw_1224	ENOG4108UJD	30S ribosomal protein S9
wcw_1225	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
wcw_1226	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
wcw_1228	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
wcw_1230	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
wcw_1231	ENOG4108173	Flavin containing amine oxidoreductase
wcw_1233	ENOG4105W5Q	DNA repair protein (RadC
wcw_1234	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
wcw_1235	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
wcw_1237	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
wcw_1241	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
wcw_1242	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
wcw_1243	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
wcw_1250	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
wcw_1261	ENOG4107QPK	)-transporter
wcw_1262	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
wcw_1263	ENOG4105E5D	amino acid
wcw_1275	ENOG4105CHU	acetyl-coa acetyltransferase
wcw_1276	ENOG4108IQE	Amp-dependent synthetase and ligase
wcw_1279	ENOG4105DEU	major facilitator superfamily
wcw_1282	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
wcw_1291	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
wcw_1295	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
wcw_1298	ENOG4105EV9	Alpha Beta Hydrolase
wcw_1300	ENOG4105CPF	Cell wall formation (By similarity)
wcw_1302	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
wcw_1303	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
wcw_1304	ENOG4105D49	3-dehydroquinate synthase
wcw_1305	ENOG4105E2X	shikimate dehydrogenase
wcw_1309	ENOG4105D9P	serine threonine protein kinase
wcw_1314	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
wcw_1316	ENOG4105BZG	amino acid carrier protein
wcw_1317	ENOG4105BZG	amino acid carrier protein
wcw_1318	ENOG4105KJM	monovalent cation h antiporter subunit g
wcw_1319	ENOG41080TA	Multiple resistance and ph regulation protein f
wcw_1320	ENOG4105SC1	monovalent cation H antiporter subunit E
wcw_1321	ENOG4108JPZ	Monovalent cation H antiporter subunit D
wcw_1322	ENOG4105MKQ	Monovalent cation H antiporter subunit C
wcw_1323	ENOG4105D65	subunit l
wcw_1325	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
wcw_1329	ENOG4105BZ1	(ABC) transporter
wcw_1331	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
wcw_1333	ENOG41082SS	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions (By similarity)
wcw_1334	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
wcw_1336	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
wcw_1337	ENOG4105E66	phosphoriboisomerase A
wcw_1339	ENOG41080Z8	PHOSPHOCARRIER protein
wcw_1341	ENOG4105DPN	Oligoendopeptidase f
wcw_1342	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
wcw_1343	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
wcw_1348	ENOG4105VUH	addiction module killer protein
wcw_1352	ENOG4105K59	histidine triad (HIT) protein
wcw_1353	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
wcw_1358	ENOG4105C25	Primosomal protein n'
wcw_1360	ENOG4105CRK	lysyL-tRNA synthetase
wcw_1369	ENOG4105C8N	cysteinyl-tRNA synthetase
wcw_1370	ENOG4105CEY	Amp-dependent synthetase and ligase
wcw_1373	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
wcw_1375	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
wcw_1376	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
wcw_1380	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
wcw_1381	ENOG4105SFS	phosphoesterase RecJ domain protein
wcw_1382	ENOG4108SP1	single-stranded DNA-binding protein
wcw_1385	ENOG4105DFU	Cell wall formation (By similarity)
wcw_1386	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
wcw_1387	ENOG4105CNI	cell division protein FtsW
wcw_1388	ENOG41069ER	domain protein
wcw_1389	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
wcw_1390	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
wcw_1393	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
wcw_1395	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
wcw_1396	ENOG4108PPE	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
wcw_1398	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
wcw_1405	ENOG4105C8J	)-transporter
wcw_1407	ENOG4105D1F	ATP-binding protein
wcw_1412	ENOG4105EMU	Dehydrogenase
wcw_1415	ENOG4105CMR	udp-glucose 4-epimerase
wcw_1423	ENOG4105C6E	dna polymerase iii
wcw_1424	ENOG41085QW	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
wcw_1425	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
wcw_1427	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
wcw_1432	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
wcw_1433	ENOG4105CNU	cell division protein FtsK
wcw_1434	ENOG4105Q2H	domain protein
wcw_1435	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
wcw_1437	ENOG41063ZQ	30S ribosomal protein S21
wcw_1438	ENOG41072GX	Peptidase M22 Glycoprotease
wcw_1439	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
wcw_1442	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
wcw_1443	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
wcw_1445	ENOG4107R1N	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
wcw_1446	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
wcw_1449	ENOG4105C5H	ABC transporter
wcw_1451	ENOG4105EUJ	GTP cyclohydrolase i
wcw_1452	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
wcw_1455	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
wcw_1457	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
wcw_1458	ENOG4108N9J	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
wcw_1459	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
wcw_1460	ENOG4107IVX	UPF0158 protein CPn_0518 CP_0235 CPj0518 CpB0539
wcw_1465	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
wcw_1466	ENOG4105C7B	Threonine dehydratase
wcw_1468	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
wcw_1469	ENOG4107QI1	Mate efflux family protein
wcw_1471	ENOG4105CHU	acetyl-coa acetyltransferase
wcw_1472	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
wcw_1473	ENOG4105E39	Enoyl-CoA hydratase
wcw_1474	ENOG4105CR4	methylisocitrate lyase
wcw_1475	ENOG4105BZN	citrate synthase
wcw_1476	ENOG4105DXD	2-methylcitrate dehydratase
wcw_1477	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
wcw_1478	ENOG4106SXF	
wcw_1479	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
wcw_1480	ENOG4108ZT0	50S ribosomal protein l17
wcw_1481	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
wcw_1482	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
wcw_1483	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
wcw_1484	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
wcw_1485	ENOG4107XE9	Binds to the 23S rRNA (By similarity)
wcw_1486	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
wcw_1487	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
wcw_1488	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
wcw_1489	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
wcw_1490	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
wcw_1491	ENOG41084J6	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
wcw_1492	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
wcw_1493	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
wcw_1494	ENOG4106GM2	50S ribosomal protein L29
wcw_1495	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
wcw_1496	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
wcw_1497	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
wcw_1498	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
wcw_1499	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
wcw_1500	ENOG4108389	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
wcw_1501	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
wcw_1502	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
wcw_1507	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
wcw_1508	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
wcw_1509	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
wcw_1510	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
wcw_1511	ENOG4107RI4	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
wcw_1515	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
wcw_1517	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
wcw_1519	ENOG4105DZ1	carboxypeptidase
wcw_1523	ENOG4105C0B	DNA polymerase III (alpha subunit)
wcw_1524	ENOG4105CXY	transporter
wcw_1526	ENOG4105CUT	histidyl-tRNA synthetase
wcw_1527	ENOG4105C9M	aspartyl-trna synthetase
wcw_1529	ENOG410801I	Peptidyl-prolyl cis-trans isomerase
wcw_1530	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
wcw_1531	ENOG4105K63	Thioredoxin
wcw_1533	ENOG4105C72	UPF0176 protein
wcw_1542	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
wcw_1543	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
wcw_1544	ENOG4105DDQ	anthranilate synthase
wcw_1545	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
wcw_1548	ENOG4108IUZ	ABC transporter
wcw_1550	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
wcw_1554	ENOG4105VB6	UPF0109 protein
wcw_1555	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
wcw_1561	ENOG4105DF5	DNA topoisomerase IV, subunit A
wcw_1562	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
wcw_1563	ENOG4105C5E	polysaccharide biosynthesis protein
wcw_1564	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
wcw_1566	ENOG4105C5S	asparaginyl-tRNA synthetase
wcw_1567	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
wcw_1568	ENOG4107X8J	Protein MurJ homolog
wcw_1570	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
wcw_1572	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
wcw_1585	ENOG4107TNS	sigma 54 modulation protein ribosomal protein S30ea
wcw_1590	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
wcw_1591	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
wcw_1592	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
wcw_1593	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
wcw_1594	ENOG4105DFF	Rod shape-determining protein mreb
wcw_1597	ENOG41081GA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity)
wcw_1598	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
wcw_1599	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
wcw_1620	ENOG4105DD5	Flagellar motor switch protein
wcw_1621	ENOG4105D9P	serine threonine protein kinase
wcw_1622	ENOG4105GVR	general secretion pathway protein D
wcw_1624	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
wcw_1626	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
wcw_1627	ENOG4105C0D	helicase
wcw_1628	ENOG4105DCF	alanine dehydrogenase
wcw_1629	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
wcw_1630	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
wcw_1636	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
wcw_1637	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
wcw_1638	ENOG4105CFG	Acts as a chaperone (By similarity)
wcw_1639	ENOG4107RA9	decarboxylase
wcw_1641	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
wcw_1643	ENOG410801I	Peptidyl-prolyl cis-trans isomerase
wcw_1644	ENOG4105D07	Signal peptide peptidase, SppA
wcw_1645	ENOG4105C2M	dna polymerase I
wcw_1646	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
wcw_1647	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
wcw_1649	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
wcw_1650	ENOG4105K46	50S ribosomal protein l27
wcw_1651	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
wcw_1652	ENOG4108JQ1	Dehydrogenase
wcw_1654	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
wcw_1655	ENOG4105DC1	bifunctional purine biosynthesis protein purh
wcw_1657	ENOG4105CP7	Triose-phosphate isomerase
wcw_1658	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
wcw_1665	ENOG4105CN1	protease
wcw_1666	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
wcw_1667	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
wcw_1669	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
wcw_1670	ENOG4107RBD	ABC, transporter
wcw_1671	ENOG4107RPQ	ABC transporter
wcw_1672	ENOG4105DIK	(ABC) transporter
wcw_1673	ENOG4107SIG	periplasmic solute binding protein
wcw_1675	ENOG4105D1F	ATP-binding protein
wcw_1678	ENOG4105E7T	carrier protein
wcw_1680	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
wcw_1681	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
wcw_1683	ENOG41090XM	Early upstream open reading frame
wcw_1684	ENOG4105CN1	protease
wcw_1685	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
wcw_1687	ENOG41083CW	dedA protein
wcw_1688	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
wcw_1692	ENOG4105D5G	Transposase
wcw_1694	ENOG4105CMM	transposase
wcw_1697	ENOG41090R7	Ferric uptake
wcw_1698	ENOG4105E7T	carrier protein
wcw_1699	ENOG4105E7T	carrier protein
wcw_1700	ENOG4105BZA	Phosphoglycerate kinase
wcw_1701	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
wcw_1702	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
wcw_1703	ENOG4105UMD	exodeoxyribonuclease X
wcw_1704	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
wcw_1705	ENOG4105K8N	protein family UPF0079, ATPase
wcw_1706	ENOG4108C2G	Protein of unknown function (DUF2709)
wcw_1708	ENOG4105C75	arginyL-tRNA synthetase
wcw_1709	ENOG4105C59	p-type ATPase
wcw_1710	ENOG4105FA0	parb-like partition protein
wcw_1713	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
wcw_1716	ENOG4107QWP	ABC-2 type transporter
wcw_1717	ENOG4107QWP	ABC-2 type transporter
wcw_1718	ENOG4105CJ1	ABC, transporter
wcw_1729	ENOG4105C2X	Arabinose 5-phosphate isomerase
wcw_1731	ENOG4105CK2	sodium dicarboxylate symporter
wcw_1732	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
wcw_1733	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
wcw_1744	ENOG4105D3G	Pseudouridine synthase
wcw_1745	ENOG4108RWN	rrna methyltransferase
wcw_1746	ENOG4105DR4	Methyltransferase
wcw_1747	ENOG4105CEV	competence damage-inducible protein
wcw_1750	ENOG4105SCY	DNAK suppressor
wcw_1751	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
wcw_1758	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
wcw_1760	ENOG4105HS1	biotin--protein ligase
wcw_1761	ENOG4105VKD	bioY protein
wcw_1767	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
wcw_1768	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
wcw_1770	ENOG4107XSR	periplasmic solute binding protein
wcw_1771	ENOG4105DIK	(ABC) transporter
wcw_1772	ENOG4107VVP	(ABC) transporter
wcw_1775	ENOG4105CDU	Replicative dna helicase
wcw_1776	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
wcw_1778	ENOG4105C2N	RNA methyltransferase TrmH family group 3
wcw_1782	ENOG4105E33	succinate dehydrogenase
wcw_1784	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
wcw_1785	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
wcw_1786	ENOG4105CSM	endonuclease III
wcw_1787	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
wcw_1788	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
wcw_1790	ENOG4105XA0	heptosyltransferase ii
wcw_1791	ENOG4108MYC	UTP-glucose-1-phosphate uridylyltransferase
wcw_1793	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
wcw_1797	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
wcw_1799	ENOG4107TVC	Glycosyl transferase, family 2
wcw_1805	ENOG4108KBE	Glycosyl transferase, family 2
wcw_1808	ENOG4105CMM	transposase
wcw_1815	ENOG4105BZS	acriflavin resistance protein
wcw_1816	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
wcw_1821	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
wcw_1822	ENOG4107QQG	Dehydrogenase
wcw_1823	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
wcw_1824	ENOG4105J5G	Transferase hexapeptide repeat containing protein
wcw_1825	ENOG4105C0D	helicase
wcw_1826	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
wcw_1831	ENOG4105QMX	Protein of unknown function (DUF1186)
wcw_1835	ENOG41083B3	HAD-superfamily subfamily IB hydrolase
wcw_1838	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
wcw_1841	ENOG4105C26	Dehydrogenase
wcw_1846	ENOG4105C26	Dehydrogenase
wcw_1847	ENOG4105EHZ	conserved protein UCP016719
wcw_1848	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
wcw_1849	ENOG4108R01	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
wcw_1854	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
wcw_1859	ENOG4105C5X	domain protein
wcw_1860	ENOG4105D3R	alkyl hydroperoxide reductase
wcw_1862	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
wcw_1863	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
wcw_1867	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
wcw_1868	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
wcw_1871	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
wcw_1878	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
wcw_1879	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
wcw_1880	ENOG4105CG3	alpha amylase, catalytic region
wcw_1881	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
wcw_1885	ENOG4105CMM	transposase
wcw_1890	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
wcw_1896	ENOG410600T	transposase
wcw_1912	ENOG4105D7Q	type ii secretion system
wcw_1913	ENOG4107QHF	type ii secretion system protein e
wcw_1914	ENOG4105E4G	Type IV pilus
wcw_1918	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
wcw_1919	ENOG4105D64	Mechanosensitive ion channel
wcw_1921	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
wcw_1923	ENOG4105C26	Dehydrogenase
wcw_1925	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
wcw_1929	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
wcw_1931	ENOG4105CJN	penicillin-binding protein
wcw_1933	ENOG4105CE9	30S ribosomal protein S2
wcw_1934	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
wcw_1935	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
wcw_1936	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
wcw_1939	ENOG4108Z0C	Uvrb UvrC protein
wcw_1940	ENOG41066A3	ATP guanido phosphotransferase
wcw_1943	ENOG4108552	Binds directly to 16S ribosomal RNA (By similarity)
wcw_1944	ENOG4105C34	Pseudouridine synthase
wcw_1949	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
wcw_1950	ENOG4105DVT	helicase
wcw_1954	ENOG4107S1W	4-alpha-glucanotransferase
wcw_1958	ENOG4105D5G	Transposase
wcw_1971	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
wcw_1973	ENOG41067XK	integral membrane protein
wcw_1977	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
wcw_1978	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
wcw_p0001	ENOG4106VZX	establishment of viral latency
wcw_p0002	ENOG4105VUH	addiction module killer protein