locus-tag	class	description
Weevi_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Weevi_0003	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
Weevi_0007	ENOG4107XMK	single-stranded DNA-binding protein
Weevi_0009	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
Weevi_0010	ENOG4105C1A	potassium transporter peripheral membrane
Weevi_0011	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
Weevi_0012	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
Weevi_0013	ENOG4105J0Q	Transcriptional regulator
Weevi_0014	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Weevi_0015	ENOG4105CHR	reductase
Weevi_0016	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
Weevi_0019	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Weevi_0020	ENOG4105K64	Glycosyl transferase, family 2
Weevi_0022	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
Weevi_0025	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Weevi_0033	ENOG4105CE1	Ferrous iron transport protein b
Weevi_0034	ENOG4105CE1	Ferrous iron transport protein b
Weevi_0036	ENOG4105CK2	sodium dicarboxylate symporter
Weevi_0055	ENOG4105C59	p-type ATPase
Weevi_0068	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Weevi_0070	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Weevi_0071	ENOG4105C01	Dihydroxy-acid dehydratase
Weevi_0072	ENOG4105C7K	acetolactate synthase
Weevi_0073	ENOG4108ZP8	Acetolactate synthase small subunit
Weevi_0074	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
Weevi_0075	ENOG4105C7B	Threonine dehydratase
Weevi_0081	ENOG4108KBJ	Inner membrane protein YkgB
Weevi_0086	ENOG4108A04	Beta-lactamase
Weevi_0088	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
Weevi_0091	ENOG4105DZR	Type I site-specific deoxyribonuclease
Weevi_0094	ENOG4107H6E	
Weevi_0124	ENOG4105KWG	Pfam:DUF1696
Weevi_0125	ENOG4105W5Q	DNA repair protein (RadC
Weevi_0149	ENOG4105PGM	cation diffusion facilitator family transporter
Weevi_0153	ENOG4105D85	methylase
Weevi_0160	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
Weevi_0162	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
Weevi_0163	ENOG4105CZN	Potassium uptake protein
Weevi_0164	ENOG4107ZYR	domain protein
Weevi_0171	ENOG4105D6N	CoA-transferase, subunit a
Weevi_0176	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Weevi_0177	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Weevi_0179	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
Weevi_0180	ENOG4107RZZ	dna polymerase iii epsilon subunit
Weevi_0181	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
Weevi_0183	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Weevi_0185	ENOG4105D3R	alkyl hydroperoxide reductase
Weevi_0186	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
Weevi_0188	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Weevi_0189	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Weevi_0194	ENOG4105CZH	peptidase
Weevi_0196	ENOG4105C26	Dehydrogenase
Weevi_0197	ENOG4105C1G	acyl-Coa dehydrogenase
Weevi_0200	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Weevi_0201	ENOG4105DQR	SNARE associated Golgi
Weevi_0202	ENOG4105E2X	shikimate dehydrogenase
Weevi_0204	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
Weevi_0205	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
Weevi_0207	ENOG4107XC4	flavin reductase domain protein, FMN-binding
Weevi_0209	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
Weevi_0212	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
Weevi_0217	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Weevi_0227	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
Weevi_0288	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
Weevi_0289	ENOG41086DT	Membrane protein of unknown function
Weevi_0290	ENOG4105ER2	Ompa motb domain protein
Weevi_0291	ENOG4109066	lysm domain bon superfamily protein
Weevi_0293	ENOG4105HDK	L-asparaginase
Weevi_0295	ENOG4105CUZ	uba thif-type nad fad binding protein
Weevi_0298	ENOG4107SNB	ankyrin repeat protein YahD
Weevi_0299	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Weevi_0300	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
Weevi_0301	ENOG4105C8Y	Acetylornithine aminotransferase
Weevi_0302	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Weevi_0303	ENOG4105CDH	Citrulline--aspartate ligase
Weevi_0304	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
Weevi_0306	ENOG4107T6X	nag kinase
Weevi_0312	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Weevi_0333	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
Weevi_0342	ENOG4105EYH	Exonuclease
Weevi_0343	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
Weevi_0347	ENOG4105C9B	Cysteine desulfurase
Weevi_0351	ENOG4108Z4V	iron-sulfur cluster assembly
Weevi_0352	ENOG4105C31	Tryptophanyl-tRNA synthetase
Weevi_0354	ENOG4105PWN	phosphate abc transporter
Weevi_0359	ENOG4105CV8	reductase
Weevi_0363	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Weevi_0365	ENOG4105CA0	peroxidase
Weevi_0367	ENOG4108KF3	Electron transport protein SCO1 SenC
Weevi_0370	ENOG4105CSR	polyphosphate kinase 2
Weevi_0376	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Weevi_0377	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Weevi_0378	ENOG4105DSJ	YicC domain protein
Weevi_0379	ENOG4105CI2	imidazolone-5-propionate hydrolase
Weevi_0380	ENOG4107QM5	aconitate hydratase
Weevi_0381	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
Weevi_0383	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
Weevi_0385	ENOG4105E4F	Isochorismate synthase
Weevi_0386	ENOG4105KA0	thioesterase Superfamily protein
Weevi_0391	ENOG4105C25	Primosomal protein n'
Weevi_0394	ENOG41081WG	50s ribosomal protein l31
Weevi_0396	ENOG4105IIU	Aminopeptidase
Weevi_0397	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
Weevi_0398	ENOG4105C1G	acyl-Coa dehydrogenase
Weevi_0399	ENOG4105CHU	acetyl-coa acetyltransferase
Weevi_0401	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
Weevi_0403	ENOG4108RMU	ferritin dps family protein
Weevi_0407	ENOG4105EMU	Dehydrogenase
Weevi_0409	ENOG41077A9	carbonic anhydrase
Weevi_0411	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
Weevi_0414	ENOG4105DFA	alanine racemase domain protein
Weevi_0416	ENOG4108JQ1	Dehydrogenase
Weevi_0417	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
Weevi_0418	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
Weevi_0421	ENOG4105D49	3-dehydroquinate synthase
Weevi_0422	ENOG4105E0X	reductase
Weevi_0425	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
Weevi_0426	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Weevi_0427	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
Weevi_0429	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
Weevi_0430	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
Weevi_0432	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
Weevi_0436	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Weevi_0438	ENOG4105FJR	Lmbe family
Weevi_0439	ENOG4108V06	Glutathione peroxidase
Weevi_0440	ENOG4105CRE	cytochrome C
Weevi_0441	ENOG4108Z0Z	intracellular protease Pfpi family
Weevi_0442	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
Weevi_0445	ENOG4105CKK	Glycosyl transferase, family 2
Weevi_0450	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
Weevi_0451	ENOG4105C26	Dehydrogenase
Weevi_0457	ENOG4105K63	Thioredoxin
Weevi_0460	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
Weevi_0464	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
Weevi_0465	ENOG41087NI	Sulfite exporter TauE/SafE
Weevi_0467	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
Weevi_0468	ENOG41077A9	carbonic anhydrase
Weevi_0469	ENOG4105E33	succinate dehydrogenase
Weevi_0480	ENOG4105C7S	Dehydrogenase
Weevi_0481	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
Weevi_0482	ENOG4105BZU	Histidine kinase
Weevi_0483	ENOG4105CJW	magnesium transporter
Weevi_0484	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Weevi_0485	ENOG4107RJ9	Cell division protein FtsX
Weevi_0487	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
Weevi_0488	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Weevi_0491	ENOG4105CYC	Transferase
Weevi_0494	ENOG4106032	Glutathionylspermidine synthase
Weevi_0496	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
Weevi_0497	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Weevi_0498	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Weevi_0499	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Weevi_0500	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Weevi_0501	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Weevi_0502	ENOG4105DCI	Phosphohydrolase
Weevi_0503	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Weevi_0504	ENOG4105K8N	protein family UPF0079, ATPase
Weevi_0505	ENOG4105DCF	alanine dehydrogenase
Weevi_0507	ENOG4105QNF	Outer membrane lipoprotein
Weevi_0508	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Weevi_0509	ENOG4105CPF	Cell wall formation (By similarity)
Weevi_0511	ENOG4105C34	Pseudouridine synthase
Weevi_0512	ENOG4105CEV	competence damage-inducible protein
Weevi_0513	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
Weevi_0515	ENOG4105CMR	udp-glucose 4-epimerase
Weevi_0519	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
Weevi_0520	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Weevi_0523	ENOG4105C27	TonB-dependent Receptor Plug
Weevi_0526	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Weevi_0527	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
Weevi_0530	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Weevi_0533	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
Weevi_0534	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
Weevi_0535	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Weevi_0537	ENOG4105KNE	Phosphatidate cytidylyltransferase
Weevi_0538	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
Weevi_0541	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
Weevi_0542	ENOG4107RJ1	sodium solute
Weevi_0546	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Weevi_0551	ENOG4105E6M	Sulphatase-modifying factor protein
Weevi_0555	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Weevi_0556	ENOG4107SM7	Transcriptional regulator
Weevi_0561	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
Weevi_0562	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Weevi_0563	ENOG4105DWT	malate dehydrogenase (quinone)
Weevi_0566	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
Weevi_0567	ENOG4105CG5	Glycosyl transferase (Group 1
Weevi_0568	ENOG4107SJB	teichoic acid biosynthesis
Weevi_0569	ENOG4105CG5	Glycosyl transferase (Group 1
Weevi_0573	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Weevi_0574	ENOG4105WMR	Protein CrcB homolog
Weevi_0578	ENOG4105CKK	Glycosyl transferase, family 2
Weevi_0580	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Weevi_0581	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
Weevi_0583	ENOG4105VIE	preprotein translocase, subunit YajC
Weevi_0585	ENOG4105M7K	Involved in the transcription termination process (By similarity)
Weevi_0586	ENOG4105BZ1	(ABC) transporter
Weevi_0588	ENOG4105Y3U	Transglycosylase-associated protein
Weevi_0589	ENOG4107QKV	phosphomannomutase
Weevi_0592	ENOG4107QX3	carboxylase
Weevi_0593	ENOG4105D3Q	Sugar transferase
Weevi_0594	ENOG4108QV3	biosynthesis protein
Weevi_0596	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Weevi_0600	ENOG4107TYR	Glycosyl Transferase
Weevi_0607	ENOG4106YN8	Prenyltransferase
Weevi_0609	ENOG4107S6X	Glycosyl transferase, family 2
Weevi_0611	ENOG4105K64	Glycosyl transferase, family 2
Weevi_0613	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
Weevi_0620	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
Weevi_0622	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
Weevi_0623	ENOG4105C34	Pseudouridine synthase
Weevi_0624	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
Weevi_0626	ENOG4108RWI	nicotinamidase
Weevi_0629	ENOG4105CSM	endonuclease III
Weevi_0630	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Weevi_0633	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Weevi_0634	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Weevi_0635	ENOG4105C2X	Arabinose 5-phosphate isomerase
Weevi_0636	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
Weevi_0638	ENOG4105C10	Electron transfer flavoprotein
Weevi_0640	ENOG4105EAA	nucleoside
Weevi_0641	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
Weevi_0643	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Weevi_0644	ENOG4105D05	Receptor
Weevi_0646	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
Weevi_0647	ENOG4108Z03	MAF-like protein
Weevi_0648	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
Weevi_0649	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Weevi_0650	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
Weevi_0655	ENOG4105VRS	hydrolase family 18
Weevi_0656	ENOG41074B2	UPF0747 protein
Weevi_0657	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
Weevi_0660	ENOG4105FQP	Beta-lactamase
Weevi_0666	ENOG4108RWN	rrna methyltransferase
Weevi_0668	ENOG4105D2N	Aldolase
Weevi_0669	ENOG4108IDZ	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
Weevi_0673	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Weevi_0675	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
Weevi_0679	ENOG4105KTH	gatB Yqey
Weevi_0680	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Weevi_0681	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
Weevi_0683	ENOG4105DFU	Cell wall formation (By similarity)
Weevi_0684	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Weevi_0686	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
Weevi_0687	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Weevi_0688	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Weevi_0689	ENOG4107XRG	penicillin-binding protein
Weevi_0691	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
Weevi_0692	ENOG4107YM1	mraZ protein
Weevi_0693	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
Weevi_0694	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
Weevi_0695	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
Weevi_0697	ENOG4105EHG	Permease protein
Weevi_0698	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
Weevi_0699	ENOG4106QJH	hemin transport protein
Weevi_0703	ENOG4105D1H	recombination factor protein RarA
Weevi_0707	ENOG4107QZC	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
Weevi_0708	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
Weevi_0711	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Weevi_0713	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
Weevi_0714	ENOG4105C0H	protease
Weevi_0719	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Weevi_0720	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Weevi_0721	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Weevi_0722	ENOG4107VNI	ribosomal protein l10
Weevi_0723	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
Weevi_0724	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Weevi_0727	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Weevi_0729	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Weevi_0730	ENOG41083X6	30S ribosomal protein S21
Weevi_0731	ENOG4105C1G	acyl-Coa dehydrogenase
Weevi_0732	ENOG41076HS	cation diffusion facilitator family transporter
Weevi_0733	ENOG4105C26	Dehydrogenase
Weevi_0736	ENOG4105CPP	Dehydrogenase, E1 component
Weevi_0742	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
Weevi_0743	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
Weevi_0744	ENOG4105RA3	Binds directly to 16S ribosomal RNA (By similarity)
Weevi_0745	ENOG4107TT5	NLP P60 protein
Weevi_0750	ENOG4108URH	decarboxylase
Weevi_0752	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
Weevi_0754	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
Weevi_0755	ENOG4108V1T	peptidylprolyl cis-trans isomerase
Weevi_0757	ENOG4105C6E	dna polymerase iii
Weevi_0758	ENOG4105CNU	cell division protein FtsK
Weevi_0760	ENOG4108M8S	permease YjgP YjgQ family protein
Weevi_0761	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
Weevi_0763	ENOG4105CGK	Exodeoxyribonuclease III
Weevi_0765	ENOG4105KNA	-acetyltransferase
Weevi_0768	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Weevi_0769	ENOG4105CN1	protease
Weevi_0774	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
Weevi_0776	ENOG4106H78	methyltransferase
Weevi_0779	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Weevi_0787	ENOG4105C5Z	peptidase
Weevi_0788	ENOG4105DUX	Transporter
Weevi_0789	ENOG4105DUX	Transporter
Weevi_0790	ENOG4105DUX	Transporter
Weevi_0792	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
Weevi_0797	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
Weevi_0798	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
Weevi_0802	ENOG4108JA2	transcriptioN-repair coupling factor
Weevi_0803	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Weevi_0804	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Weevi_0805	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Weevi_0806	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Weevi_0807	ENOG4105GKE	subunit e
Weevi_0808	ENOG4107EEP	NADH dehydrogenase (quinone) (EC 1.6.99.5)
Weevi_0810	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
Weevi_0811	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Weevi_0812	ENOG4105DF2	NADH dehydrogenase subunit j
Weevi_0813	ENOG4108373	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Weevi_0814	ENOG4105D65	subunit l
Weevi_0815	ENOG4105C8S	subunit m
Weevi_0816	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Weevi_0818	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
Weevi_0819	ENOG4105CGP	Urocanate hydratase
Weevi_0820	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
Weevi_0822	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
Weevi_0824	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Weevi_0827	ENOG4105C58	cytochrome c oxidase accessory protein ccog
Weevi_0828	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
Weevi_0832	ENOG4105C59	p-type ATPase
Weevi_0836	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
Weevi_0840	ENOG4105K5M	30s ribosomal protein S16
Weevi_0841	ENOG4107YAY	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Weevi_0843	ENOG4105CX6	glutaminyL-tRNA synthetase
Weevi_0845	ENOG4105W5Q	DNA repair protein (RadC
Weevi_0848	ENOG4107XGZ	Hydrolase
Weevi_0849	ENOG4107QP8	phosphohexose isomerase
Weevi_0851	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Weevi_0855	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
Weevi_0856	ENOG4105DJT	lAO AO transport system ATPase
Weevi_0872	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
Weevi_0877	ENOG4105DTN	riboflavin biosynthesis protein ribF
Weevi_0878	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
Weevi_0879	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Weevi_0880	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
Weevi_0881	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Weevi_0882	ENOG4105CDV	Ompa motb domain protein
Weevi_0883	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Weevi_0884	ENOG4105C8F	Beta-lactamase domain protein
Weevi_0885	ENOG4105MA4	psp1 domain protein
Weevi_0887	ENOG4108JQC	penicillin-binding protein 1A
Weevi_0888	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
Weevi_0889	ENOG4108IYU	L-aspartate oxidase
Weevi_0891	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
Weevi_0893	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
Weevi_0894	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
Weevi_0895	ENOG41080R2	UPF0102 protein
Weevi_0896	ENOG4105DQR	SNARE associated Golgi
Weevi_0897	ENOG4105DQR	SNARE associated Golgi
Weevi_0902	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
Weevi_0904	ENOG4105CFP	Peptidase U32
Weevi_0905	ENOG4105C2N	RNA methyltransferase TrmH family group 3
Weevi_0910	ENOG41060VI	Involved in DNA repair and RecF pathway recombination (By similarity)
Weevi_0912	ENOG4105C79	DNA protecting protein DprA
Weevi_0914	ENOG4108S4H	thioesterase Superfamily protein
Weevi_0917	ENOG4105D7Z	glutathione synthase
Weevi_0919	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
Weevi_0920	ENOG41082J7	Rhodanese domain protein
Weevi_0921	ENOG4105VRT	cytoplasmic protein
Weevi_0922	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
Weevi_0923	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Weevi_0925	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Weevi_0926	ENOG4105E39	Enoyl-CoA hydratase
Weevi_0928	ENOG4105CRQ	synthase (Component I)
Weevi_0929	ENOG4105DDQ	anthranilate synthase
Weevi_0930	ENOG4107RI6	Anthranilate phosphoribosyltransferase
Weevi_0931	ENOG4105DK0	Indole-3-glycerol phosphate synthase
Weevi_0932	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
Weevi_0933	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Weevi_0951	ENOG4105D7W	serine acetyltransferase
Weevi_0952	ENOG4105D3Q	Sugar transferase
Weevi_0962	ENOG4107QQG	Dehydrogenase
Weevi_0963	ENOG4108IAJ	Nad-dependent epimerase dehydratase
Weevi_0964	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
Weevi_0966	ENOG4105F0N	pyrophosphate phospho-hydrolase
Weevi_0968	ENOG4105CPP	Dehydrogenase, E1 component
Weevi_0971	ENOG4105C37	(CBS) domain
Weevi_0978	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Weevi_0979	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Weevi_0981	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
Weevi_0982	ENOG4107RWD	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
Weevi_0983	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
Weevi_0985	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
Weevi_0988	ENOG4105MJ2	Competence protein
Weevi_0989	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
Weevi_0998	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Weevi_1000	ENOG4107T8J	thymidine kinase
Weevi_1001	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Weevi_1002	ENOG4105D78	K07001 NTE family protein
Weevi_1003	ENOG41080AX	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
Weevi_1004	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Weevi_1007	ENOG4108ZG0	Ompa motb domain protein
Weevi_1009	ENOG4105CMQ	Chloride channel
Weevi_1010	ENOG4105C2I	pirin domain protein
Weevi_1011	ENOG4108JQ1	Dehydrogenase
Weevi_1012	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
Weevi_1015	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
Weevi_1017	ENOG4108YZG	isomerase
Weevi_1018	ENOG4105BZA	Phosphoglycerate kinase
Weevi_1020	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Weevi_1024	ENOG4107QVM	von Willebrand factor, type A
Weevi_1027	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
Weevi_1029	ENOG4105WG6	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
Weevi_1030	ENOG4108Y6J	UPF0403 protein
Weevi_1032	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
Weevi_1036	ENOG4105C85	amino acid
Weevi_1038	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Weevi_1041	ENOG4105Q26	Siderophore-interacting protein
Weevi_1043	ENOG4108IPW	abc transporter atp-binding protein
Weevi_1044	ENOG4105CM4	permease protein
Weevi_1045	ENOG4105DHS	permease protein
Weevi_1046	ENOG4105FA2	dna polymerase iii
Weevi_1047	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
Weevi_1051	ENOG4108IJ0	Aspartate ammonia-lyase
Weevi_1053	ENOG4105DNZ	Alpha Beta Hydrolase
Weevi_1055	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Weevi_1056	ENOG4105CUT	histidyl-tRNA synthetase
Weevi_1059	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
Weevi_1060	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Weevi_1061	ENOG4105CBX	hi0933 family
Weevi_1067	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Weevi_1070	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Weevi_1071	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Weevi_1072	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Weevi_1073	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
Weevi_1074	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
Weevi_1076	ENOG4108R6K	riboflavin synthase, subunit alpha
Weevi_1079	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
Weevi_1081	ENOG4105D75	Capsular exopolysaccharide family
Weevi_1084	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Weevi_1087	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Weevi_1088	ENOG4105KRF	dihydroneopterin aldolase
Weevi_1089	ENOG4108Z6B	deaminase
Weevi_1093	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
Weevi_1094	ENOG4105C0F	tryptophanase EC 4.1.99.1
Weevi_1096	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Weevi_1097	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Weevi_1098	ENOG4105D7N	magnesium and cobalt transport protein CorA
Weevi_1100	ENOG4105C27	TonB-dependent Receptor Plug
Weevi_1104	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
Weevi_1108	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Weevi_1110	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Weevi_1115	ENOG4105FE9	pseudouridine synthase
Weevi_1116	ENOG4105K46	50S ribosomal protein l27
Weevi_1117	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
Weevi_1119	ENOG4105CE1	Ferrous iron transport protein b
Weevi_1121	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
Weevi_1123	ENOG4105EN6	Membrane
Weevi_1124	ENOG41088SP	formiminoglutamate hydrolase
Weevi_1125	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Weevi_1126	ENOG4105DJV	ribulose-phosphate 3-epimerase
Weevi_1129	ENOG4105CRQ	synthase (Component I)
Weevi_1133	ENOG41083MR	nifu domain-containing protein
Weevi_1135	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
Weevi_1139	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Weevi_1140	ENOG4105CFH	Aspartokinase
Weevi_1144	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
Weevi_1146	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
Weevi_1150	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
Weevi_1152	ENOG4105C28	cystathionine
Weevi_1154	ENOG4105FE9	pseudouridine synthase
Weevi_1156	ENOG4105C5Z	peptidase
Weevi_1157	ENOG4105C03	ribonuclease
Weevi_1158	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
Weevi_1160	ENOG4108UUM	single-stranded DNA-binding protein
Weevi_1164	ENOG41080RH	Thioredoxin
Weevi_1165	ENOG4105D3R	alkyl hydroperoxide reductase
Weevi_1170	ENOG4105VG1	fes assembly suf system protein
Weevi_1173	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Weevi_1174	ENOG4105BZU	Histidine kinase
Weevi_1176	ENOG4105C8T	Leucyl-tRNA synthetase
Weevi_1183	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Weevi_1184	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
Weevi_1185	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
Weevi_1186	ENOG4105E9K	Isocitrate dehydrogenase
Weevi_1189	ENOG4105C84	Histidine ammonia-lyase
Weevi_1190	ENOG4105EUJ	GTP cyclohydrolase i
Weevi_1191	ENOG4105C8N	cysteinyl-tRNA synthetase
Weevi_1192	ENOG4105C27	TonB-dependent Receptor Plug
Weevi_1197	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
Weevi_1200	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
Weevi_1201	ENOG4105VHG	atp synthase
Weevi_1202	ENOG4107Z65	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
Weevi_1203	ENOG4107Z4P	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Weevi_1204	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
Weevi_1205	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
Weevi_1208	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
Weevi_1210	ENOG4105C5H	ABC transporter
Weevi_1212	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
Weevi_1216	ENOG4105CHM	Aminotransferase
Weevi_1227	ENOG4105CAY	ferredoxin--nadp reductase
Weevi_1229	ENOG4105C2M	dna polymerase I
Weevi_1233	ENOG4105DHJ	ABC, transporter
Weevi_1236	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
Weevi_1239	ENOG4105CAT	Cytidine monophosphate kinase
Weevi_1242	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
Weevi_1243	ENOG4105C5H	ABC transporter
Weevi_1244	ENOG4108DJF	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Weevi_1246	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
Weevi_1247	ENOG4105C2N	RNA methyltransferase TrmH family group 3
Weevi_1252	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Weevi_1253	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Weevi_1255	ENOG4108I0Z	Aconitate hydratase
Weevi_1257	ENOG4107UGT	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
Weevi_1261	ENOG4105D64	Mechanosensitive ion channel
Weevi_1263	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Weevi_1265	ENOG4105C22	threonyL-tRNA synthetase
Weevi_1266	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
Weevi_1267	ENOG4105VJV	50s ribosomal protein L35
Weevi_1268	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Weevi_1269	ENOG4105D5P	Methylmalonyl-coA mutase
Weevi_1271	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Weevi_1273	ENOG4106BRA	Membrane
Weevi_1275	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
Weevi_1278	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
Weevi_1281	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Weevi_1284	ENOG4105D9R	oxidoreductase
Weevi_1285	ENOG4108S4H	thioesterase Superfamily protein
Weevi_1286	ENOG4107RW9	nh(3)-dependent nad( ) synthetase
Weevi_1290	ENOG41072GX	Peptidase M22 Glycoprotease
Weevi_1294	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Weevi_1296	ENOG4105EV9	Alpha Beta Hydrolase
Weevi_1297	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
Weevi_1298	ENOG4105CUY	Mechanosensitive ion channel
Weevi_1300	ENOG41090IP	Required for maturation of 30S ribosomal subunits (By similarity)
Weevi_1301	ENOG4105CHV	Transcription elongation factor NusA
Weevi_1302	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Weevi_1303	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Weevi_1304	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
Weevi_1305	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
Weevi_1306	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Weevi_1309	ENOG4105D7W	serine acetyltransferase
Weevi_1311	ENOG4105BZ1	(ABC) transporter
Weevi_1315	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
Weevi_1316	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
Weevi_1317	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
Weevi_1318	ENOG4105CJ1	ABC, transporter
Weevi_1319	ENOG4105C3G	gtp-binding protein
Weevi_1320	ENOG41061HS	cysteine-type endopeptidase activity
Weevi_1321	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
Weevi_1323	ENOG4105DF5	DNA topoisomerase IV, subunit A
Weevi_1328	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Weevi_1329	ENOG4105DR5	peptidase
Weevi_1330	ENOG4108Z5V	transcriptional regulator, merr family
Weevi_1331	ENOG4105C0B	DNA polymerase III (alpha subunit)
Weevi_1332	ENOG4105K63	Thioredoxin
Weevi_1334	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Weevi_1335	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Weevi_1337	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
Weevi_1343	ENOG41080WS	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
Weevi_1347	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Weevi_1348	ENOG4105CN1	protease
Weevi_1349	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
Weevi_1351	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Weevi_1352	ENOG4105VG0	50S ribosomal protein l34
Weevi_1353	ENOG4105CAK	Cell division ATP-binding protein ftsE
Weevi_1356	ENOG4107TYR	Glycosyl Transferase
Weevi_1358	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
Weevi_1359	ENOG4105D4P	Coproporphyrinogen iii oxidase
Weevi_1360	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
Weevi_1361	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Weevi_1369	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Weevi_1370	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Weevi_1371	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Weevi_1372	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Weevi_1373	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Weevi_1374	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Weevi_1375	ENOG41082S5	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Weevi_1376	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Weevi_1377	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Weevi_1378	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Weevi_1379	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Weevi_1380	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Weevi_1382	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Weevi_1383	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Weevi_1384	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
Weevi_1385	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Weevi_1386	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Weevi_1387	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
Weevi_1388	ENOG4105ETU	transcriptional activator (TenA
Weevi_1389	ENOG4105DWF	phosphomethylpyrimidine kinase
Weevi_1390	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Weevi_1391	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
Weevi_1392	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Weevi_1393	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
Weevi_1394	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
Weevi_1395	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Weevi_1396	ENOG41084HK	50S ribosomal protein L30
Weevi_1397	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Weevi_1398	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Weevi_1399	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
Weevi_1400	ENOG410864M	50S ribosomal protein L36
Weevi_1401	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Weevi_1402	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Weevi_1403	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Weevi_1404	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Weevi_1405	ENOG4108ZT0	50S ribosomal protein l17
Weevi_1413	ENOG4105CFG	Acts as a chaperone (By similarity)
Weevi_1416	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Weevi_1421	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Weevi_1423	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Weevi_1425	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
Weevi_1426	ENOG4105E1F	short-chain dehydrogenase reductase
Weevi_1428	ENOG4105FDR	Membrane
Weevi_1429	ENOG4105CK7	Sodium proline symporter
Weevi_1430	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Weevi_1434	ENOG4105D7A	ATP-binding protein
Weevi_1435	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Weevi_1441	ENOG4105DF6	Fe-S oxidoreductase
Weevi_1442	ENOG4105DF6	Fe-S oxidoreductase
Weevi_1444	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Weevi_1446	ENOG4105KME	endoribonuclease L-psp
Weevi_1448	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
Weevi_1450	ENOG4105WXV	50S ribosomal protein L32
Weevi_1451	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
Weevi_1452	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Weevi_1453	ENOG4107V87	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity)
Weevi_1455	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Weevi_1459	ENOG4105CNI	cell division protein FtsW
Weevi_1460	ENOG4107RVG	penicillin-binding protein
Weevi_1463	ENOG4105DFF	Rod shape-determining protein mreb
Weevi_1464	ENOG4105D07	Signal peptide peptidase, SppA
Weevi_1465	ENOG4105EEI	dihydropteroate synthase
Weevi_1466	ENOG4105CDV	Ompa motb domain protein
Weevi_1468	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Weevi_1470	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Weevi_1472	ENOG4107SN7	NLP P60 protein
Weevi_1473	ENOG4105DGW	oligopeptidase A
Weevi_1475	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
Weevi_1476	ENOG4105KDC	50s ribosomal protein l28
Weevi_1477	ENOG41083ND	50S ribosomal protein L33
Weevi_1479	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
Weevi_1484	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
Weevi_1489	ENOG4105C9A	Phoh family
Weevi_1490	ENOG4105C0P	Mg chelatase subunit ChlI
Weevi_1492	ENOG4107R0V	Pyruvate dehydrogenase
Weevi_1498	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Weevi_1499	ENOG4105CP7	Triose-phosphate isomerase
Weevi_1500	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Weevi_1503	ENOG4105EEI	dihydropteroate synthase
Weevi_1505	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Weevi_1506	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
Weevi_1507	ENOG4105E09	nadh pyrophosphatase
Weevi_1510	ENOG41083IP	HIT family
Weevi_1511	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Weevi_1513	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Weevi_1516	ENOG4105C02	permease
Weevi_1518	ENOG4108IUX	(ABC) transporter
Weevi_1519	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
Weevi_1523	ENOG4105C75	arginyL-tRNA synthetase
Weevi_1525	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
Weevi_1527	ENOG4105CIN	aminoacyl-histidine dipeptidase
Weevi_1529	ENOG4108WQI	RNA Polymerase
Weevi_1531	ENOG4105CTQ	phosphohexokinase
Weevi_1533	ENOG4105CN9	Peptidase m42 family protein
Weevi_1534	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Weevi_1536	ENOG4105C12	Phosphoribosylglycinamide synthetase
Weevi_1538	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Weevi_1539	ENOG4108UJD	30S ribosomal protein S9
Weevi_1540	ENOG4105CE9	30S ribosomal protein S2
Weevi_1541	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Weevi_1542	ENOG4105C5Q	Transcriptional regulator
Weevi_1544	ENOG4105BZ1	(ABC) transporter
Weevi_1545	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Weevi_1549	ENOG4105CHR	reductase
Weevi_1550	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Weevi_1551	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Weevi_1554	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Weevi_1559	ENOG4105CJ1	ABC, transporter
Weevi_1562	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Weevi_1564	ENOG4107IQ5	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Weevi_1565	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Weevi_1571	ENOG4105K64	Glycosyl transferase, family 2
Weevi_1573	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
Weevi_1577	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Weevi_1581	ENOG4107RAQ	aminopeptidase
Weevi_1582	ENOG41080B9	Binds together with S18 to 16S ribosomal RNA (By similarity)
Weevi_1583	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
Weevi_1584	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Weevi_1586	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
Weevi_1587	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Weevi_1589	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
Weevi_1590	ENOG4107U9T	Pfam:Ribonuclease_BN
Weevi_1591	ENOG4105EYW	Ion transport protein
Weevi_1592	ENOG4105ECP	epimerase
Weevi_1595	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
Weevi_1596	ENOG4107REN	Carbamoyltransferase
Weevi_1598	ENOG4107QI1	Mate efflux family protein
Weevi_1600	ENOG4105CJ1	ABC, transporter
Weevi_1602	ENOG4105SFS	phosphoesterase RecJ domain protein
Weevi_1604	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
Weevi_1608	ENOG4105CDY	transcriptional regulatory protein
Weevi_1611	ENOG4105DFU	Cell wall formation (By similarity)
Weevi_1613	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Weevi_1614	ENOG4107TE5	Lipid kinase
Weevi_1616	ENOG4108ETH	Formylglycinamide ribotide synthetase
Weevi_1619	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
Weevi_1620	ENOG4107QUV	Domain protein
Weevi_1621	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
Weevi_1622	ENOG4105D1Q	UPF0246 protein
Weevi_1624	ENOG4105BZM	domain protein
Weevi_1626	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Weevi_1627	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Weevi_1628	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
Weevi_1630	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
Weevi_1637	ENOG4107QN2	dihydrolipoyl dehydrogenase
Weevi_1640	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Weevi_1646	ENOG4108UJU	UPF0301 protein
Weevi_1647	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
Weevi_1648	ENOG4105K70	DNA-binding protein
Weevi_1649	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Weevi_1650	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Weevi_1651	ENOG4105CUG	Oligopeptidase b
Weevi_1653	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Weevi_1654	ENOG4108HCJ	Hydrolase
Weevi_1655	ENOG4105EE5	Membrane protein terC
Weevi_1658	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Weevi_1660	ENOG4105DR9	pseudouridine synthase
Weevi_1661	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Weevi_1663	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Weevi_1665	ENOG4105DU6	RNA polymerase
Weevi_1666	ENOG4108QBX	(LipO)protein
Weevi_1671	ENOG4105C9M	aspartyl-trna synthetase
Weevi_1672	ENOG4105CUB	amino acid
Weevi_1673	ENOG4105IIU	Aminopeptidase
Weevi_1674	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
Weevi_1675	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
Weevi_1682	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Weevi_1684	ENOG4105C5X	domain protein
Weevi_1685	ENOG4105EA8	2-Nitropropane dioxygenase
Weevi_1687	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Weevi_1692	ENOG4105CHM	Aminotransferase
Weevi_1693	ENOG4107R0I	Cell wall formation (By similarity)
Weevi_1694	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
Weevi_1695	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
Weevi_1696	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
Weevi_1697	ENOG4105CBC	glutamate synthase
Weevi_1698	ENOG4105DEF	Extracellular solute-binding protein, family 5
Weevi_1699	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Weevi_1703	ENOG4105DU1	integral membrane protein, terc
Weevi_1704	ENOG4105D17	glycoside hydrolase, family 3 domain protein
Weevi_1705	ENOG4105CPK	Glycosyl transferase (Group 1
Weevi_1706	ENOG4105MIR	Phenylalanine 4-monooxygenase
Weevi_1707	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Weevi_1708	ENOG4105EHZ	conserved protein UCP016719
Weevi_1711	ENOG4108IUZ	ABC transporter
Weevi_1712	ENOG4107RH7	Nicotinate phosphoribosyltransferase
Weevi_1714	ENOG4105VEJ	Heat shock protein
Weevi_1715	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Weevi_1719	ENOG4105M6F	mutator MutT protein
Weevi_1724	ENOG4108D64	Protein of unknown function (DUF493)
Weevi_1726	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Weevi_1728	ENOG4108VVK	transcriptional Regulator, AsnC
Weevi_1731	ENOG4105EJQ	L-serine dehydratase
Weevi_1736	ENOG4107TPS	domain protein
Weevi_1744	ENOG4107SFQ	iron-sulfur binding
Weevi_1751	ENOG4105DR5	peptidase
Weevi_1754	ENOG4105MGM	doxx family
Weevi_1759	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Weevi_1760	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Weevi_1762	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
Weevi_1764	ENOG4105DHU	Bile acid
Weevi_1765	ENOG4108K8S	endonuclease I
Weevi_1766	ENOG4105F32	YngK protein
Weevi_1776	ENOG4105EUB	pirin domain protein
Weevi_1777	ENOG4105C59	p-type ATPase
Weevi_1780	ENOG41083MR	nifu domain-containing protein
Weevi_1781	ENOG4108Z0R	Transferase
Weevi_1785	ENOG4105DWY	Agmatine deiminase
Weevi_1786	ENOG4105C1G	acyl-Coa dehydrogenase
Weevi_1788	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Weevi_1790	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Weevi_1791	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Weevi_1795	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
Weevi_1797	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
Weevi_1799	ENOG4105DFG	type I secretion outer membrane protein
Weevi_1802	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Weevi_1803	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
Weevi_1804	ENOG4105C5H	ABC transporter
Weevi_1806	ENOG4107KET	secretion protein, HlyD family
Weevi_1813	ENOG4105DBI	uridine monophosphokinase
Weevi_1815	ENOG4105C29	acyl-CoA thioesterase
Weevi_1817	ENOG4107QI1	Mate efflux family protein
Weevi_1819	ENOG4108IQE	Amp-dependent synthetase and ligase
Weevi_1828	ENOG4105C6X	Major Facilitator
Weevi_1830	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Weevi_1840	ENOG4105CRK	lysyL-tRNA synthetase
Weevi_1843	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
Weevi_1844	ENOG4105E0A	ABC, transporter
Weevi_1845	ENOG4105TVJ	transport system, permease
Weevi_1848	ENOG4105C27	TonB-dependent Receptor Plug
Weevi_1851	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
Weevi_1853	ENOG4105E9M	CRISPR-associated protein, Csn1 family
Weevi_1854	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Weevi_1855	ENOG4105KT5	UmuD protein
Weevi_1856	ENOG4108RAV	Conserved protein
Weevi_1857	ENOG4105C98	muts2 protein
Weevi_1858	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
Weevi_1863	ENOG4105D05	Receptor
Weevi_1864	ENOG4107RPQ	ABC transporter
Weevi_1865	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Weevi_1866	ENOG4107TPS	domain protein
Weevi_1868	ENOG4105C9Q	fumarate hydratase class II
Weevi_1871	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Weevi_1876	ENOG4107ZXU	DSBA oxidoreductase
Weevi_1877	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Weevi_1880	ENOG4105EN6	Membrane
Weevi_1881	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Weevi_1882	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Weevi_1884	ENOG4105DR5	peptidase
Weevi_1887	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
Weevi_1888	ENOG4105DC7	peptidase M24
Weevi_1890	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
Weevi_1891	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Weevi_1900	ENOG4108Z66	YbaK ebsC protein
Weevi_1903	ENOG41090A1	ferritin
Weevi_1905	ENOG4108S4H	thioesterase Superfamily protein
Weevi_1906	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
Weevi_1908	ENOG4105K6H	D-cysteine desulfhydrase
Weevi_1911	ENOG4107QI6	Cysteine desulfurase
Weevi_1913	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Weevi_1914	ENOG4105DXN	mazG family
Weevi_1916	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Weevi_1917	ENOG4107ZNS	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
Weevi_1918	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
Weevi_1919	ENOG4105KPY	Small multidrug resistance protein
Weevi_1920	ENOG4105CKI	cobalamin synthesis protein
Weevi_1922	ENOG4105EAH	synthase
Weevi_1924	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Weevi_1925	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
Weevi_1927	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
Weevi_1931	ENOG4108K8S	endonuclease I
Weevi_1932	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
Weevi_1935	ENOG4105H4N	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
Weevi_1938	ENOG4105CHU	acetyl-coa acetyltransferase
Weevi_1939	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
Weevi_1940	ENOG4105CDU	Replicative dna helicase
Weevi_1943	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Weevi_1944	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
Weevi_1951	ENOG4105C27	TonB-dependent Receptor Plug
Weevi_1960	ENOG4108C33	Resolvase
Weevi_1963	ENOG4105C0D	helicase
Weevi_1963	ENOG4105C0D	helicase
Weevi_1969	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
Weevi_1970	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
Weevi_1972	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Weevi_1975	ENOG4106WTF	Glycosyl transferase, family 2
Weevi_1976	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
Weevi_1979	ENOG4107SJB	teichoic acid biosynthesis
Weevi_1981	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Weevi_1982	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Weevi_1986	ENOG4108D32	Methyltransferase
Weevi_1990	ENOG4105C3M	thioredoxin reductase
Weevi_1992	ENOG4105C59	p-type ATPase
Weevi_1994	ENOG4107TUM	Amidinotransferase
Weevi_1998	ENOG4108DBC	nitroreductase
Weevi_1999	ENOG4108Z5K	methylglyoxal synthase
Weevi_2001	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Weevi_2002	ENOG4105D52	delta-aminolevulinic acid dehydratase
Weevi_2003	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
Weevi_2005	ENOG4105D3G	Pseudouridine synthase
Weevi_2006	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
Weevi_2011	ENOG41090A1	ferritin
Weevi_2012	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Weevi_2014	ENOG4105CGH	5'-nucleotidase
Weevi_2015	ENOG4105C1G	acyl-Coa dehydrogenase
Weevi_2016	ENOG4105EXW	epimerase dehydratase
Weevi_2017	ENOG4105C9K	Endothelin-converting enzyme 1
Weevi_2018	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
Weevi_2019	ENOG4105C9K	Endothelin-converting enzyme 1
Weevi_2021	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Weevi_2023	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
Weevi_2024	ENOG4107W2A	UPF0173 metal-dependent hydrolase
Weevi_2029	ENOG4105D5P	Methylmalonyl-coA mutase
Weevi_2031	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Weevi_2037	ENOG4105CZH	peptidase
Weevi_2038	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Weevi_2039	ENOG4105C5S	asparaginyl-tRNA synthetase
Weevi_2041	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
Weevi_2042	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Weevi_2043	ENOG4105F8V	Hydrolase, tatD family
Weevi_2046	ENOG4105DEN	Luciferase family
Weevi_2054	ENOG4105DGW	oligopeptidase A
Weevi_2062	ENOG4105KHC	sulfurtransferase
Weevi_2063	ENOG4105DEU	major facilitator superfamily
Weevi_2065	ENOG4105C8Y	Acetylornithine aminotransferase
Weevi_2066	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Weevi_2067	ENOG4105CSA	Coproporphyrinogen iii oxidase
Weevi_2069	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Weevi_2074	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
Weevi_2076	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
Weevi_2081	ENOG4105CPC	Aldo Keto reductase
Weevi_2082	ENOG4105F27	Major Facilitator
Weevi_2083	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Weevi_2084	ENOG4105CEP	NADH dehydrogenase
Weevi_2085	ENOG4105C8Y	Acetylornithine aminotransferase
Weevi_2088	ENOG4105I3K	Ferric uptake regulator, Fur family
Weevi_2089	ENOG4105C4R	Atp-dependent dna helicase
Weevi_2090	ENOG4105BZG	amino acid carrier protein
Weevi_2095	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
Weevi_2097	ENOG4105FA0	parb-like partition protein
Weevi_2098	ENOG4107QJE	Chromosome Partitioning Protein
Weevi_2101	ENOG4105CSV	Glutaminase
Weevi_2105	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
Weevi_R0033	ENOG4105C26	Dehydrogenase