locus-tag	class	description
KHQ31_00005	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KHQ31_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KHQ31_00020	COG2501	S4 domain
KHQ31_00025	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KHQ31_00030	COG0187	DNA topoisomerase II activity
KHQ31_00040	COG1368	sulfuric ester hydrolase activity
KHQ31_00095	COG1737	Transcriptional regulator
KHQ31_00100	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KHQ31_00125	COG2233	PERMEase
KHQ31_00130	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KHQ31_00185	COG2252	PERMEase
KHQ31_00195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHQ31_00205	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KHQ31_00215	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHQ31_00230	COG0495	leucyl-tRNA aminoacylation
KHQ31_00240	COG2244	polysaccharide biosynthetic process
KHQ31_00255	COG0531	amino acid
KHQ31_00265	COG1162	GTPase activity
KHQ31_00275	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KHQ31_00280	COG1074	ATP-dependent DNA helicase activity
KHQ31_00285	COG1064	alcohol dehydrogenase
KHQ31_00295	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KHQ31_00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KHQ31_00305	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KHQ31_00310	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHQ31_00315	COG4493	Belongs to the UPF0637 family
KHQ31_00320	COG0360	Binds together with S18 to 16S ribosomal RNA
KHQ31_00325	COG0629	single-stranded DNA binding
KHQ31_00330	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KHQ31_00345	COG0745	RESPONSE REGULATOR receiver
KHQ31_00350	COG5002	protein histidine kinase activity
KHQ31_00365	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KHQ31_00370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHQ31_00380	COG1078	dGTPase activity
KHQ31_00385	COG0561	phosphatase activity
KHQ31_00390	COG3343	RNA polymerase activity
KHQ31_00395	COG0504	CTP synthase activity
KHQ31_00400	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KHQ31_00415	COG2337	Toxic component of a toxin-antitoxin (TA) module
KHQ31_00420	COG3973	AAA domain
KHQ31_00425	COG0180	Tryptophanyl-tRNA synthetase
KHQ31_00430	COG0248	Ppx GppA phosphatase
KHQ31_00450	COG0194	GDP metabolic process
KHQ31_00475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHQ31_00480	COG0765	amino acid transport
KHQ31_00485	COG0765	amino acid transport
KHQ31_00490	COG4166	transmembrane transport
KHQ31_00495	COG0601	transmembrane transport
KHQ31_00500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHQ31_00505	COG0444	Belongs to the ABC transporter superfamily
KHQ31_00510	COG4608	Belongs to the ABC transporter superfamily
KHQ31_00525	COG0359	binds to the 23S rRNA
KHQ31_00530	COG0305	Participates in initiation and elongation during chromosome replication
KHQ31_00535	COG2814	Major facilitator Superfamily
KHQ31_00550	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KHQ31_00560	COG0492	ferredoxin-NADP+ reductase activity
KHQ31_00565	COG0588	phosphoglycerate mutase activity
KHQ31_00570	COG1388	LysM domain
KHQ31_00570	COG1134	teichoic acid transport
KHQ31_00585	COG0586	Pfam SNARE associated Golgi protein
KHQ31_00600	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KHQ31_00605	COG1077	Cell shape determining protein MreB Mrl
KHQ31_00615	COG0772	Belongs to the SEDS family
KHQ31_00620	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KHQ31_00635	COG0561	phosphatase activity
KHQ31_00640	COG0577	efflux transmembrane transporter activity
KHQ31_00640	COG1136	(ABC) transporter
KHQ31_00650	COG2188	Transcriptional regulator
KHQ31_00655	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KHQ31_00665	COG2252	PERMEase
KHQ31_00675	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KHQ31_00690	COG0561	phosphatase activity
KHQ31_00695	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KHQ31_00705	COG0750	zinc metalloprotease
KHQ31_00710	COG0442	prolyl-tRNA aminoacylation
KHQ31_00715	COG2176	DNA-directed DNA polymerase activity
KHQ31_00720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHQ31_00755	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KHQ31_00785	COG2183	response to ionizing radiation
KHQ31_00795	COG2217	Heavy metal translocating P-type atpase
KHQ31_00850	COG0110	maltose O-acetyltransferase activity
KHQ31_00860	COG2199	diguanylate cyclase activity
KHQ31_00865	COG3706	GGDEF domain
KHQ31_00885	COG1869	D-ribose catabolic process
KHQ31_00890	COG2076	Multidrug Resistance protein
KHQ31_00895	COG0668	transmembrane transport
KHQ31_00900	COG4975	Glucose uptake
KHQ31_00905	COG0166	Belongs to the GPI family
KHQ31_00910	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KHQ31_00915	COG1302	Protein conserved in bacteria
KHQ31_00920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHQ31_00930	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KHQ31_00935	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KHQ31_00940	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KHQ31_00945	COG0049	tRNA binding
KHQ31_00950	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KHQ31_00955	COG0673	inositol 2-dehydrogenase activity
KHQ31_00965	COG2801	Transposase and inactivated derivatives
KHQ31_00970	COG3842	ATPase activity
KHQ31_00980	COG1177	transmembrane transport
KHQ31_00985	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KHQ31_00990	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KHQ31_00995	COG1950	PFAM Membrane protein of
KHQ31_01000	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KHQ31_01005	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KHQ31_01015	COG0492	ferredoxin-NADP+ reductase activity
KHQ31_01035	COG0149	triose-phosphate isomerase activity
KHQ31_01050	COG0557	exoribonuclease II activity
KHQ31_01055	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KHQ31_01060	COG0765	amino acid transport
KHQ31_01065	COG1126	abc transporter atp-binding protein
KHQ31_01070	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KHQ31_01075	COG0280	phosphate acetyltransferase
KHQ31_01080	COG0802	atpase or kinase
KHQ31_01095	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KHQ31_01120	COG0540	Belongs to the ATCase OTCase family
KHQ31_01130	COG0505	Belongs to the CarA family
KHQ31_01135	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KHQ31_01140	COG0284	orotidine-5'-phosphate decarboxylase activity
KHQ31_01145	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KHQ31_01150	COG0438	transferase activity, transferring glycosyl groups
KHQ31_01155	COG0438	transferase activity, transferring glycosyl groups
KHQ31_01165	COG1368	sulfuric ester hydrolase activity
KHQ31_01200	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHQ31_01200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHQ31_01205	COG0025	NhaP-type Na H and K H
KHQ31_01210	COG0084	hydrolase, TatD family'
KHQ31_01220	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KHQ31_01225	COG1253	flavin adenine dinucleotide binding
KHQ31_01235	COG4466	Protein conserved in bacteria
KHQ31_01240	COG2131	deaminase
KHQ31_01250	COG1316	TRANSCRIPTIONal
KHQ31_01260	COG1968	undecaprenyl-diphosphatase activity
KHQ31_01280	COG0193	aminoacyl-tRNA hydrolase activity
KHQ31_01285	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KHQ31_01290	COG2244	polysaccharide biosynthetic process
KHQ31_01295	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KHQ31_01320	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KHQ31_01325	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KHQ31_01445	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KHQ31_01455	COG1271	oxidase subunit
KHQ31_01460	COG1294	oxidase, subunit
KHQ31_01465	COG4988	ABC transporter
KHQ31_01470	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KHQ31_01475	COG1705	Flagellar rod assembly protein muramidase FlgJ
KHQ31_01480	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KHQ31_01510	COG2723	6-phospho-beta-galactosidase activity
KHQ31_01515	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KHQ31_01530	COG0494	nUDIX hydrolase
KHQ31_01540	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KHQ31_01550	COG1388	LysM domain
KHQ31_01560	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KHQ31_01565	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHQ31_01570	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHQ31_01580	COG4120	Belongs to the binding-protein-dependent transport system permease family
KHQ31_01585	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KHQ31_01590	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHQ31_01605	COG2003	Belongs to the UPF0758 family
KHQ31_01610	COG1077	Cell shape determining protein MreB Mrl
KHQ31_01630	COG0765	amino acid transport
KHQ31_01645	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KHQ31_01655	COG0730	response to heat
KHQ31_01665	COG0833	amino acid
KHQ31_01675	COG2264	protein methyltransferase activity
KHQ31_01680	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KHQ31_01685	COG2001	Belongs to the MraZ family
KHQ31_01690	COG0275	rRNA processing
KHQ31_01700	COG0768	penicillin binding
KHQ31_01710	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KHQ31_01715	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KHQ31_01735	COG1799	cell septum assembly
KHQ31_01740	COG0762	integral membrane protein
KHQ31_01745	COG2302	S4 RNA-binding domain
KHQ31_01750	COG3599	regulation of cell shape
KHQ31_01755	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KHQ31_01770	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KHQ31_01775	COG0217	transcriptional regulatory protein
KHQ31_01780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KHQ31_01790	COG4537	Required for transformation and DNA binding
KHQ31_01820	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KHQ31_01825	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KHQ31_01830	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHQ31_01830	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KHQ31_01835	COG0631	protein serine/threonine phosphatase activity
KHQ31_01840	COG2815	serine threonine protein kinase
KHQ31_01840	COG0515	serine threonine protein kinase
KHQ31_01845	COG1162	GTPase activity
KHQ31_01850	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KHQ31_01855	COG1564	THIamine pyrophosphokinase
KHQ31_01860	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KHQ31_01870	COG1461	Dihydroxyacetone kinase
KHQ31_01875	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KHQ31_01880	COG0416	fatty acid biosynthetic process
KHQ31_01885	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHQ31_01890	COG0571	ribonuclease III activity
KHQ31_01895	COG1196	nuclear chromosome segregation
KHQ31_01900	COG0552	protein localization to endoplasmic reticulum
KHQ31_01905	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KHQ31_01910	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KHQ31_01915	COG0228	four-way junction DNA binding
KHQ31_01920	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KHQ31_01925	COG0336	Belongs to the RNA methyltransferase TrmD family
KHQ31_01930	COG0335	large ribosomal subunit rRNA binding
KHQ31_01935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHQ31_01940	COG1942	4-Oxalocrotonate Tautomerase
KHQ31_01950	COG0494	nUDIX hydrolase
KHQ31_01955	COG1428	Deoxynucleoside kinase
KHQ31_01960	COG1970	mechanosensitive ion channel activity
KHQ31_01965	COG0561	phosphatase activity
KHQ31_01990	COG4862	establishment of competence for transformation
KHQ31_01995	COG2514	catechol 2,3-dioxygenase activity
KHQ31_02000	COG1164	Oligoendopeptidase f
KHQ31_02015	COG0006	proline dipeptidase activity
KHQ31_02020	COG1609	Transcriptional regulator
KHQ31_02055	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KHQ31_02060	COG3425	synthase
KHQ31_02070	COG0860	N-Acetylmuramoyl-L-alanine amidase
KHQ31_02075	COG0124	histidyl-tRNA synthetase
KHQ31_02080	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KHQ31_02085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHQ31_02090	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KHQ31_02095	COG1610	YqeY-like protein
KHQ31_02100	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KHQ31_02105	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KHQ31_02110	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KHQ31_02115	COG1381	Involved in DNA repair and RecF pathway recombination
KHQ31_02120	COG0752	glycyl-tRNA synthetase alpha subunit
KHQ31_02125	COG0751	glycine-tRNA ligase activity
KHQ31_02140	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KHQ31_02160	COG2706	6-phosphogluconolactonase activity
KHQ31_02170	COG1674	ftsk spoiiie
KHQ31_02175	COG4152	abc transporter atp-binding protein
KHQ31_02180	COG1668	transmembrane transport
KHQ31_02185	COG0584	glycerophosphoryl diester phosphodiesterase
KHQ31_02195	COG0322	excinuclease ABC activity
KHQ31_02210	COG1739	Uncharacterized protein family UPF0029
KHQ31_02215	COG0384	phenazine biosynthesis protein PhzF
KHQ31_02225	COG0516	GMP reductase activity
KHQ31_02225	COG0517	IMP dehydrogenase activity
KHQ31_02230	COG0632	four-way junction helicase activity
KHQ31_02235	COG2255	four-way junction helicase activity
KHQ31_02240	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KHQ31_02285	COG1862	Preprotein translocase
KHQ31_02290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHQ31_02295	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KHQ31_02300	COG0513	Belongs to the DEAD box helicase family
KHQ31_02305	COG0110	maltose O-acetyltransferase activity
KHQ31_02310	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KHQ31_02325	COG3906	Belongs to the UPF0473 family
KHQ31_02330	COG3906	Belongs to the UPF0473 family
KHQ31_02335	COG1555	photosystem II stabilization
KHQ31_02335	COG1596	polysaccharide export
KHQ31_02340	COG0658	competence protein
KHQ31_02340	COG2333	competence protein COMEC
KHQ31_02345	COG1466	dna polymerase III delta subunit
KHQ31_02350	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KHQ31_02355	COG0268	Binds directly to 16S ribosomal RNA
KHQ31_02390	COG3716	PTS system mannose fructose sorbose family IID component
KHQ31_02405	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KHQ31_02420	COG1193	negative regulation of DNA recombination
KHQ31_02425	COG3118	belongs to the thioredoxin family
KHQ31_02435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KHQ31_02440	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KHQ31_02450	COG2357	RelA SpoT domain protein
KHQ31_02460	COG0564	pseudouridine synthase activity
KHQ31_02465	COG2239	Acts as a magnesium transporter
KHQ31_02470	COG0779	Required for maturation of 30S ribosomal subunits
KHQ31_02475	COG0195	Participates in both transcription termination and antitermination
KHQ31_02480	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KHQ31_02490	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KHQ31_02495	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KHQ31_02505	COG0657	acetylesterase activity
KHQ31_02510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHQ31_02515	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KHQ31_02525	COG0196	riboflavin kinase activity
KHQ31_02545	COG3142	Participates in the control of copper homeostasis
KHQ31_02550	COG1307	EDD domain protein, DegV family
KHQ31_02555	COG1307	EDD domain protein, DegV family
KHQ31_02560	COG0277	FAD linked oxidase domain protein
KHQ31_02565	COG4479	Belongs to the UPF0346 family
KHQ31_02575	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHQ31_02580	COG0758	DNA mediated transformation
KHQ31_02590	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHQ31_02595	COG4974	Belongs to the 'phage' integrase family
KHQ31_02605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHQ31_02610	COG2271	Major facilitator Superfamily
KHQ31_02625	COG1940	carbohydrate kinase activity
KHQ31_02630	COG2723	6-phospho-beta-galactosidase activity
KHQ31_02650	COG2814	Major facilitator Superfamily
KHQ31_02655	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KHQ31_02660	COG0187	DNA topoisomerase II activity
KHQ31_02665	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHQ31_02685	COG1227	inorganic diphosphatase activity
KHQ31_02710	COG3448	diguanylate cyclase activity
KHQ31_02710	COG4175	Glycine betaine
KHQ31_02740	COG1011	Hydrolase
KHQ31_02755	COG5503	Protein of unknown function (DUF1447)
KHQ31_02765	COG0242	peptide deformylase activity
KHQ31_02770	COG4476	Belongs to the UPF0223 family
KHQ31_02775	COG0483	inositol monophosphate 1-phosphatase activity
KHQ31_02780	COG1217	gtp-binding protein TYPA
KHQ31_02785	COG0772	Belongs to the SEDS family
KHQ31_02790	COG4471	UPF0298 protein
KHQ31_02795	COG0742	ribosomal rna small subunit methyltransferase
KHQ31_02800	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KHQ31_02805	COG3480	Lon protease (S16) C-terminal proteolytic domain
KHQ31_02810	COG0477	Major facilitator Superfamily
KHQ31_02815	COG0358	DNA primase activity
KHQ31_02820	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KHQ31_02830	COG0745	RESPONSE REGULATOR receiver
KHQ31_02835	COG5002	protein histidine kinase activity
KHQ31_02840	COG0572	uridine kinase
KHQ31_02845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHQ31_02855	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KHQ31_02860	COG0670	Belongs to the BI1 family
KHQ31_02885	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KHQ31_02890	COG0237	dephospho-CoA kinase activity
KHQ31_02900	COG1484	DNA-dependent DNA replication
KHQ31_02915	COG0745	RESPONSE REGULATOR receiver
KHQ31_02920	COG5002	protein histidine kinase activity
KHQ31_02935	COG0626	cystathionine gamma-synthase activity
KHQ31_02945	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHQ31_02955	COG0488	(ABC) transporter
KHQ31_02970	COG2910	NAD(P)H-binding
KHQ31_02990	COG1304	FMN binding
KHQ31_03000	COG2826	transposase and inactivated derivatives, IS30 family
KHQ31_03020	COG1136	(ABC) transporter
KHQ31_03020	COG0577	efflux transmembrane transporter activity
KHQ31_03025	COG0577	efflux transmembrane transporter activity
KHQ31_03035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHQ31_03040	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KHQ31_03065	COG1705	Flagellar rod assembly protein muramidase FlgJ
KHQ31_03065	COG3942	CHAP domain
KHQ31_03105	COG0433	COG0433 Predicted ATPase
KHQ31_03150	COG1674	ftsk spoiiie
KHQ31_03165	COG2910	NAD(P)H-binding
KHQ31_03205	COG1609	Transcriptional regulator
KHQ31_03210	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KHQ31_03215	COG1272	protein, Hemolysin III
KHQ31_03235	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KHQ31_03240	COG0439	Biotin carboxylase
KHQ31_03245	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KHQ31_03250	COG0511	ligase activity, forming carbon-carbon bonds
KHQ31_03255	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KHQ31_03280	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHQ31_03290	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KHQ31_03295	COG2755	lipolytic protein G-D-S-L family
KHQ31_03295	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KHQ31_03300	COG0446	pyridine nucleotide-disulphide oxidoreductase
KHQ31_03325	COG0351	phosphomethylpyrimidine kinase
KHQ31_03330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHQ31_03335	COG2022	thiamine diphosphate biosynthetic process
KHQ31_03350	COG0352	thiamine-phosphate diphosphorylase activity
KHQ31_03360	COG0584	glycerophosphoryl diester phosphodiesterase
KHQ31_03375	COG0561	phosphatase activity
KHQ31_03380	COG2199	diguanylate cyclase activity
KHQ31_03390	COG1719	4-vinyl reductase, 4VR
KHQ31_03395	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KHQ31_03405	COG1131	(ABC) transporter
KHQ31_03410	COG0537	adenosine 5'-monophosphoramidase activity
KHQ31_03420	COG0556	nucleotide-excision repair
KHQ31_03440	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KHQ31_03480	COG3299	homolog of phage Mu protein gp47
KHQ31_03530	COG0228	four-way junction DNA binding
KHQ31_03580	COG1783	phage Terminase large subunit
KHQ31_03655	COG1484	DNA-dependent DNA replication
KHQ31_03665	COG0629	single-stranded DNA binding
KHQ31_03675	COG3723	Recombinational DNA repair protein, rece pathway
KHQ31_03700	COG1396	sequence-specific DNA binding
KHQ31_03715	COG3561	AntA/AntB antirepressor
KHQ31_03755	COG1388	LysM domain
KHQ31_03755	COG0860	N-Acetylmuramoyl-L-alanine amidase
KHQ31_03895	COG0193	aminoacyl-tRNA hydrolase activity
KHQ31_03990	COG4974	Belongs to the 'phage' integrase family
KHQ31_03995	COG0116	Belongs to the methyltransferase superfamily
KHQ31_04005	COG3599	regulation of cell shape
KHQ31_04010	COG4474	Belongs to the UPF0398 family
KHQ31_04015	COG3331	DNA recombination
KHQ31_04025	COG0366	Alpha amylase catalytic
KHQ31_04025	COG5263	repeat protein
KHQ31_04050	COG0017	Asparaginyl-tRNA synthetase
KHQ31_04060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KHQ31_04060	COG1199	ATP-dependent helicase activity
KHQ31_04065	COG0582	viral genome integration into host DNA
KHQ31_04140	COG1304	FMN binding
KHQ31_04150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHQ31_04160	COG0706	membrane insertase activity
KHQ31_04190	COG0105	UTP biosynthetic process
KHQ31_04195	COG0531	amino acid
KHQ31_04205	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KHQ31_04210	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KHQ31_04215	COG2855	membrane
KHQ31_04225	COG1215	transferase activity, transferring glycosyl groups
KHQ31_04235	COG0183	Belongs to the thiolase family
KHQ31_04255	COG0390	transport system, permease component
KHQ31_04260	COG4619	ABC transporter
KHQ31_04265	COG2267	carboxylic ester hydrolase activity
KHQ31_04270	COG2390	Transcriptional regulator
KHQ31_04280	COG1136	(ABC) transporter
KHQ31_04285	COG0366	Alpha amylase catalytic
KHQ31_04295	COG1609	Transcriptional regulator
KHQ31_04300	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KHQ31_04305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHQ31_04310	COG1696	Membrane protein involved in D-alanine export
KHQ31_04335	COG0481	GTPase activity
KHQ31_04355	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KHQ31_04360	COG3475	LICD family
KHQ31_04375	COG4708	membrane
KHQ31_04395	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KHQ31_04400	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KHQ31_04415	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHQ31_04420	COG2195	Cleaves the N-terminal amino acid of tripeptides
KHQ31_04425	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KHQ31_04430	COG2384	SAM-dependent methyltransferase
KHQ31_04450	COG0457	Tetratricopeptide repeat
KHQ31_04470	COG2807	transmembrane transport
KHQ31_04475	COG4720	Psort location CytoplasmicMembrane, score
KHQ31_04480	COG0351	phosphomethylpyrimidine kinase
KHQ31_04500	COG1215	transferase activity, transferring glycosyl groups
KHQ31_04500	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KHQ31_04505	COG1215	transferase activity, transferring glycosyl groups
KHQ31_04505	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KHQ31_04510	COG0438	transferase activity, transferring glycosyl groups
KHQ31_04525	COG1160	GTP binding
KHQ31_04530	COG0539	negative regulation of cytoplasmic translation
KHQ31_04535	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KHQ31_04545	COG0514	ATP-dependent DNA helicase (RecQ)
KHQ31_04555	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KHQ31_04560	COG1187	pseudouridine synthase activity
KHQ31_04565	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KHQ31_04570	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KHQ31_04575	COG0456	acetyltransferase
KHQ31_04585	COG2996	Protein conserved in bacteria
KHQ31_04595	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KHQ31_04600	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KHQ31_04605	COG0149	triose-phosphate isomerase activity
KHQ31_04620	COG3835	regulator
KHQ31_04625	COG0475	glutathione-regulated potassium exporter activity
KHQ31_04635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KHQ31_04640	COG0587	DNA-directed DNA polymerase activity
KHQ31_04655	COG0488	(ABC) transporter
KHQ31_04660	COG0617	tRNA 3'-terminal CCA addition
KHQ31_04675	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KHQ31_04705	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KHQ31_04725	COG1316	TRANSCRIPTIONal
KHQ31_04740	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KHQ31_05005	COG1396	sequence-specific DNA binding
KHQ31_05050	COG0052	Belongs to the universal ribosomal protein uS2 family
KHQ31_05055	COG2827	Endonuclease containing a URI domain
KHQ31_05060	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KHQ31_05065	COG0204	Acyl-transferase
KHQ31_05070	COG3763	UPF0154 protein
KHQ31_05075	COG4224	UPF0291 protein
KHQ31_05080	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KHQ31_05085	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KHQ31_05085	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KHQ31_05090	COG1234	tRNA 3'-trailer cleavage
KHQ31_05105	COG0484	heat shock protein binding
KHQ31_05110	COG0443	Heat shock 70 kDa protein
KHQ31_05115	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KHQ31_05120	COG1420	regulation of RNA biosynthetic process
KHQ31_05135	COG0463	Glycosyl transferase, family 2
KHQ31_05150	COG0024	Methionine aminopeptidase
KHQ31_05155	COG0463	Glycosyl transferase, family 2
KHQ31_05155	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KHQ31_05160	COG1682	transport, permease protein
KHQ31_05165	COG1388	LysM domain
KHQ31_05165	COG1134	teichoic acid transport
KHQ31_05175	COG2309	aminopeptidase activity
KHQ31_05180	COG1278	Cold shock
KHQ31_05190	COG2814	Major facilitator Superfamily
KHQ31_05195	COG1388	LysM domain
KHQ31_05200	COG1072	(Pantothenic acid kinase))
KHQ31_05205	COG3973	AAA domain
KHQ31_05210	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KHQ31_05215	COG1058	Belongs to the CinA family
KHQ31_05215	COG1546	Belongs to the CinA family
KHQ31_05220	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KHQ31_05225	COG1426	Protein conserved in bacteria
KHQ31_05235	COG0612	Peptidase, M16
KHQ31_05240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHQ31_05255	COG0789	Transcriptional regulator
KHQ31_05260	COG1070	Carbohydrate kinase
KHQ31_05265	COG3481	metal-dependent phosphohydrolase, HD sub domain
KHQ31_05270	COG4717	serine-type aminopeptidase activity
KHQ31_05270	COG4717	serine-type aminopeptidase activity
KHQ31_05280	COG3679	Belongs to the UPF0342 family
KHQ31_05285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KHQ31_05290	COG1438	arginine binding
KHQ31_05295	COG0018	arginyl-trna synthetase
KHQ31_05310	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KHQ31_05320	COG1597	lipid kinase activity
KHQ31_05325	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHQ31_05335	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHQ31_05340	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KHQ31_05340	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KHQ31_05385	COG0667	Aldo Keto reductase
KHQ31_05390	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHQ31_05395	COG0167	dihydroorotate dehydrogenase activity
KHQ31_05400	COG3859	Proton-coupled thiamine transporter YuaJ
KHQ31_05410	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KHQ31_05415	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KHQ31_05420	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KHQ31_05425	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KHQ31_05430	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KHQ31_05435	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KHQ31_05455	COG4684	Psort location CytoplasmicMembrane, score
KHQ31_05460	COG0436	Aminotransferase
KHQ31_05470	COG0436	Aminotransferase
KHQ31_05485	COG0083	homoserine kinase activity
KHQ31_05505	COG1321	iron dependent repressor
KHQ31_05505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KHQ31_05515	COG3764	Sortase (surface protein transpeptidase)
KHQ31_05520	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KHQ31_05525	COG0513	Belongs to the DEAD box helicase family
KHQ31_05530	COG0673	inositol 2-dehydrogenase activity
KHQ31_05535	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHQ31_05540	COG0501	Belongs to the peptidase M48B family
KHQ31_05545	COG1704	LemA family
KHQ31_05565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KHQ31_05570	COG0562	UDP-galactopyranose mutase
KHQ31_05575	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KHQ31_05585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KHQ31_05595	COG0505	Belongs to the CarA family
KHQ31_05600	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KHQ31_05605	COG0564	pseudouridine synthase activity
KHQ31_05615	COG1757	Na H antiporter
KHQ31_05620	COG1113	amino acid transport
KHQ31_05635	COG0126	phosphoglycerate kinase activity
KHQ31_05665	COG0737	Belongs to the 5'-nucleotidase family
KHQ31_05710	COG3716	PTS system mannose fructose sorbose family IID component
KHQ31_05715	COG3715	PTS system
KHQ31_05795	COG1098	S1 RNA binding domain
KHQ31_05805	COG0586	Pfam SNARE associated Golgi protein
KHQ31_05810	COG1758	RNA polymerase activity
KHQ31_05815	COG0194	GDP metabolic process
KHQ31_05820	COG0497	DNA recombination
KHQ31_05825	COG1438	arginine binding
KHQ31_05830	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KHQ31_05840	COG1722	exodeoxyribonuclease VII activity
KHQ31_05845	COG1570	exodeoxyribonuclease VII activity
KHQ31_05850	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KHQ31_05855	COG4720	Psort location CytoplasmicMembrane, score
KHQ31_05865	COG2348	transferase activity, transferring amino-acyl groups
KHQ31_05885	COG0363	glucosamine-6-phosphate deaminase activity
KHQ31_05890	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KHQ31_05900	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KHQ31_05905	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KHQ31_05915	COG1323	Belongs to the UPF0348 family
KHQ31_05925	COG0799	negative regulation of ribosome biogenesis
KHQ31_05930	COG1713	HD superfamily hydrolase involved in NAD metabolism
KHQ31_05935	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KHQ31_05945	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KHQ31_05955	COG1181	Belongs to the D-alanine--D-alanine ligase family
KHQ31_05965	COG0531	amino acid
KHQ31_05970	COG0459	protein refolding
KHQ31_05975	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KHQ31_05980	COG0488	(ABC) transporter
KHQ31_05990	COG0525	valine-tRNA ligase activity
KHQ31_05995	COG1279	arginine transmembrane transporter activity
KHQ31_06000	COG0589	response to stress
KHQ31_06015	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KHQ31_06030	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KHQ31_06040	COG3557	Belongs to the UPF0374 family
KHQ31_06045	COG2137	regulation of response to DNA damage stimulus
KHQ31_06050	COG0704	Plays a role in the regulation of phosphate uptake
KHQ31_06055	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KHQ31_06065	COG0581	inorganic phosphate transmembrane transporter activity
KHQ31_06070	COG0573	inorganic phosphate transmembrane transporter activity
KHQ31_06075	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KHQ31_06090	COG0393	Putative heavy-metal-binding
KHQ31_06100	COG4470	Protein conserved in bacteria
KHQ31_06105	COG0737	Belongs to the 5'-nucleotidase family
KHQ31_06115	COG0006	proline dipeptidase activity
KHQ31_06135	COG0596	Alpha beta hydrolase
KHQ31_06140	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KHQ31_06145	COG1169	isochorismate synthase
KHQ31_06160	COG0531	amino acid
KHQ31_06170	COG2814	Major facilitator Superfamily
KHQ31_06180	COG1063	alcohol dehydrogenase
KHQ31_06185	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KHQ31_06190	COG0813	purine-nucleoside phosphorylase activity
KHQ31_06195	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KHQ31_06200	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KHQ31_06205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KHQ31_06215	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KHQ31_06220	COG1447	Phosphotransferase system cellobiose-specific component IIA
KHQ31_06245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHQ31_06265	COG4608	Belongs to the ABC transporter superfamily
KHQ31_06270	COG0444	Belongs to the ABC transporter superfamily
KHQ31_06275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHQ31_06280	COG0601	transmembrane transport
KHQ31_06285	COG4166	transmembrane transport
KHQ31_06300	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KHQ31_06305	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KHQ31_06310	COG2271	Major facilitator Superfamily
KHQ31_06345	COG0174	glutamine synthetase
KHQ31_06350	COG0789	Transcriptional regulator
KHQ31_06355	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KHQ31_06370	COG1940	carbohydrate kinase activity
KHQ31_06390	COG0768	penicillin binding
KHQ31_06400	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KHQ31_06405	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KHQ31_06410	COG0072	phenylalanine-tRNA ligase activity
KHQ31_06410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHQ31_06415	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KHQ31_06420	COG1733	regulation of RNA biosynthetic process
KHQ31_06430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHQ31_06450	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KHQ31_06460	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KHQ31_06465	COG0653	protein targeting
KHQ31_06480	COG0756	dUTP diphosphatase activity
KHQ31_06485	COG2388	GCN5-related N-acetyl-transferase
KHQ31_06495	COG3942	CHAP domain
KHQ31_06495	COG1388	LysM domain
KHQ31_06500	COG0542	response to heat
KHQ31_06505	COG0604	alcohol dehydrogenase
KHQ31_06510	COG0028	Belongs to the TPP enzyme family
KHQ31_06545	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KHQ31_06560	COG0740	serine-type endopeptidase activity
KHQ31_06565	COG1481	regulation of sporulation
KHQ31_06570	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KHQ31_06580	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KHQ31_06620	COG0101	tRNA pseudouridine synthase activity
KHQ31_06630	COG1122	ATPase activity
KHQ31_06640	COG3594	Acyltransferase
KHQ31_06660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KHQ31_06665	COG1121	(ABC) transporter
KHQ31_06670	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KHQ31_06675	COG0222	ribosome binding
KHQ31_06680	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KHQ31_06685	COG0081	regulation of translation
KHQ31_06690	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KHQ31_06695	COG0250	Participates in transcription elongation, termination and antitermination
KHQ31_06715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHQ31_06720	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KHQ31_06725	COG0215	cysteine-tRNA ligase activity
KHQ31_06730	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KHQ31_06735	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KHQ31_06740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KHQ31_06750	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KHQ31_06760	COG0203	ribosomal protein L17
KHQ31_06765	COG0202	RNA polymerase activity
KHQ31_06770	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KHQ31_06775	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KHQ31_06780	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KHQ31_06785	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KHQ31_06800	COG0200	Binds to the 23S rRNA
KHQ31_06805	COG1841	ribosomal large subunit assembly
KHQ31_06810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KHQ31_06815	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KHQ31_06820	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KHQ31_06825	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KHQ31_06830	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KHQ31_06835	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KHQ31_06840	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KHQ31_06850	COG0255	Belongs to the universal ribosomal protein uL29 family
KHQ31_06855	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KHQ31_06860	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KHQ31_06865	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KHQ31_06870	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KHQ31_06875	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KHQ31_06880	COG0089	rRNA binding
KHQ31_06890	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KHQ31_06895	COG0051	transcription antitermination factor activity, RNA binding
KHQ31_06905	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KHQ31_06920	COG1214	PFAM Peptidase M22, glycoprotease
KHQ31_06925	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KHQ31_06945	COG3870	Protein conserved in bacteria
KHQ31_06950	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KHQ31_06960	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KHQ31_06965	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KHQ31_06970	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KHQ31_06985	COG2813	Specifically methylates the guanine in position
KHQ31_07020	COG1979	alcohol dehydrogenase
KHQ31_07025	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHQ31_07030	COG0085	RNA polymerase activity
KHQ31_07035	COG0542	response to heat
KHQ31_07040	COG4463	regulation of RNA biosynthetic process
KHQ31_07060	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KHQ31_07065	COG1428	Deoxynucleoside kinase
KHQ31_07080	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KHQ31_07085	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KHQ31_07090	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KHQ31_07095	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KHQ31_07100	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHQ31_07105	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KHQ31_07110	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHQ31_07115	COG0356	it plays a direct role in the translocation of protons across the membrane
KHQ31_07120	COG2233	PERMEase
KHQ31_07130	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KHQ31_07135	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KHQ31_07140	COG0009	L-threonylcarbamoyladenylate synthase
KHQ31_07145	COG2890	protein-(glutamine-N5) methyltransferase activity
KHQ31_07155	COG1435	thymidine kinase activity
KHQ31_07160	COG3442	glutamine amidotransferase
KHQ31_07165	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KHQ31_07170	COG1482	cell wall glycoprotein biosynthetic process
KHQ31_07190	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KHQ31_07220	COG1132	(ABC) transporter
KHQ31_07225	COG1132	(ABC) transporter
KHQ31_07230	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KHQ31_07235	COG0588	phosphoglycerate mutase activity
KHQ31_07265	COG0454	-acetyltransferase
KHQ31_07275	COG2610	gluconate transmembrane transporter activity
KHQ31_07280	COG0708	Exodeoxyribonuclease III
KHQ31_07290	COG1012	belongs to the aldehyde dehydrogenase family
KHQ31_07290	COG1454	alcohol dehydrogenase
KHQ31_07295	COG2235	arginine
KHQ31_07300	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KHQ31_07305	COG0531	amino acid
KHQ31_07320	COG3590	peptidase
KHQ31_07335	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
KHQ31_07340	COG2188	Transcriptional regulator
KHQ31_07345	COG1418	mRNA catabolic process
KHQ31_07360	COG0488	(ABC) transporter
KHQ31_07375	COG1121	(ABC) transporter
KHQ31_07385	COG1846	Transcriptional regulator
KHQ31_07390	COG3091	SprT-like family
KHQ31_07425	COG3104	oligopeptide transport
KHQ31_07435	COG5002	protein histidine kinase activity
KHQ31_07440	COG0745	RESPONSE REGULATOR receiver
KHQ31_07450	COG0012	GTP binding
KHQ31_07455	COG4481	Protein conserved in bacteria
KHQ31_07460	COG1475	DNA binding
KHQ31_07465	COG1192	Involved in chromosome partitioning
KHQ31_07470	COG0357	Ribosomal RNA small subunit methyltransferase G
KHQ31_07475	COG1194	a g-specific adenine glycosylase
KHQ31_07490	COG5002	protein histidine kinase activity
KHQ31_07495	COG0745	RESPONSE REGULATOR receiver
KHQ31_07500	COG0318	PFAM AMP-dependent synthetase and ligase
KHQ31_07505	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KHQ31_07515	COG1335	isochorismatase
KHQ31_07525	COG4443	Transcriptional Coactivator p15 (PC4)
KHQ31_07530	COG0252	asparaginase activity
KHQ31_07535	COG0531	amino acid
KHQ31_07545	COG1063	alcohol dehydrogenase
KHQ31_07550	COG1682	transport, permease protein
KHQ31_07555	COG1388	LysM domain
KHQ31_07555	COG1134	teichoic acid transport
KHQ31_07570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KHQ31_07595	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KHQ31_07605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KHQ31_07610	COG1554	hydrolase, family 65, central catalytic
KHQ31_07615	COG1263	PTS System
KHQ31_07615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHQ31_07615	COG2190	(PTS) system
KHQ31_07620	COG2190	(PTS) system
KHQ31_07625	COG2188	Transcriptional regulator
KHQ31_07630	COG1511	domain protein
KHQ31_07630	COG1511	domain protein
KHQ31_07635	COG1959	2 iron, 2 sulfur cluster binding
KHQ31_07645	COG2153	protein acetylation
KHQ31_07660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHQ31_07685	COG0657	acetylesterase activity
KHQ31_07690	COG1113	amino acid transport
KHQ31_07695	COG0628	permease
KHQ31_07715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHQ31_07720	COG0765	amino acid transport
KHQ31_07725	COG1126	abc transporter atp-binding protein
KHQ31_07735	COG0640	Transcriptional regulator
KHQ31_07740	COG2217	Heavy metal translocating P-type atpase
KHQ31_07750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHQ31_07755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KHQ31_07775	COG0028	Belongs to the TPP enzyme family
KHQ31_07785	COG0656	L-ascorbic acid biosynthetic process
KHQ31_07790	COG1733	regulation of RNA biosynthetic process
KHQ31_07795	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KHQ31_07815	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KHQ31_07820	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KHQ31_07825	COG1113	amino acid transport
KHQ31_07830	COG0569	domain protein
KHQ31_07840	COG0706	membrane insertase activity
KHQ31_07845	COG0594	ribonuclease P activity