locus-tag	class	description
WS08_0001	COG0230	Belongs to the bacterial ribosomal protein bL34 family
WS08_0003	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
WS08_0005	COG2501	S4 domain
WS08_0006	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
WS08_0007	COG0187	DNA topoisomerase II activity
WS08_0008	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
WS08_0009	COG1368	sulfuric ester hydrolase activity
WS08_0013	COG1737	Transcriptional regulator
WS08_0014	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
WS08_0019	COG2233	PERMEase
WS08_0020	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
WS08_0021	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
WS08_0022	COG2252	PERMEase
WS08_0024	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WS08_0027	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
WS08_0028	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WS08_0030	COG2818	Glycosylase
WS08_0032	COG0495	leucyl-tRNA aminoacylation
WS08_0033	COG2244	polysaccharide biosynthetic process
WS08_0036	COG0531	amino acid
WS08_0038	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
WS08_0039	COG1074	ATP-dependent DNA helicase activity
WS08_0040	COG1064	alcohol dehydrogenase
WS08_0043	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
WS08_0044	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
WS08_0045	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
WS08_0046	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WS08_0047	COG4493	Belongs to the UPF0637 family
WS08_0048	COG0360	Binds together with S18 to 16S ribosomal RNA
WS08_0049	COG0629	single-stranded DNA binding
WS08_0050	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
WS08_0051	COG0745	RESPONSE REGULATOR receiver
WS08_0052	COG5002	protein histidine kinase activity
WS08_0055	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
WS08_0056	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WS08_0058	COG1078	dGTPase activity
WS08_0059	COG0561	phosphatase activity
WS08_0060	COG3343	RNA polymerase activity
WS08_0061	COG0504	CTP synthase activity
WS08_0062	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
WS08_0066	COG2337	Toxic component of a toxin-antitoxin (TA) module
WS08_0067	COG3973	AAA domain
WS08_0074	COG0194	GDP metabolic process
WS08_0078	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WS08_0079	COG0765	amino acid transport
WS08_0080	COG0765	amino acid transport
WS08_0081	COG4166	transmembrane transport
WS08_0082	COG4166	transmembrane transport
WS08_0083	COG0601	transmembrane transport
WS08_0084	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WS08_0085	COG0444	Belongs to the ABC transporter superfamily
WS08_0086	COG4608	Belongs to the ABC transporter superfamily
WS08_0088	COG0359	binds to the 23S rRNA
WS08_0089	COG0305	Participates in initiation and elongation during chromosome replication
WS08_0090	COG2814	Major facilitator Superfamily
WS08_0093	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
WS08_0095	COG0492	ferredoxin-NADP+ reductase activity
WS08_0096	COG0588	phosphoglycerate mutase activity
WS08_0097	COG1134	teichoic acid transport
WS08_0097	COG1388	LysM domain
WS08_0100	COG0586	Pfam SNARE associated Golgi protein
WS08_0104	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WS08_0105	COG1077	Cell shape determining protein MreB Mrl
WS08_0107	COG0772	Belongs to the SEDS family
WS08_0108	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
WS08_0109	COG0561	phosphatase activity
WS08_0110	COG0577	efflux transmembrane transporter activity
WS08_0110	COG1136	(ABC) transporter
WS08_0113	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
WS08_0115	COG2252	PERMEase
WS08_0121	COG0561	phosphatase activity
WS08_0122	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
WS08_0123	COG4589	Belongs to the CDS family
WS08_0124	COG0750	zinc metalloprotease
WS08_0125	COG0442	prolyl-tRNA aminoacylation
WS08_0126	COG2176	DNA-directed DNA polymerase activity
WS08_0127	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WS08_0129	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
WS08_0134	COG2183	response to ionizing radiation
WS08_0136	COG2217	Heavy metal translocating P-type atpase
WS08_0160	COG3706	GGDEF domain
WS08_0161	COG0716	FMN binding
WS08_0162	COG2199	diguanylate cyclase activity
WS08_0167	COG1869	D-ribose catabolic process
WS08_0169	COG2076	Multidrug Resistance protein
WS08_0170	COG0668	transmembrane transport
WS08_0171	COG4975	Glucose uptake
WS08_0172	COG0166	Belongs to the GPI family
WS08_0173	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
WS08_0174	COG1302	Protein conserved in bacteria
WS08_0175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WS08_0177	COG0291	Belongs to the bacterial ribosomal protein bL35 family
WS08_0178	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
WS08_0179	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
WS08_0180	COG0049	tRNA binding
WS08_0181	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
WS08_0182	COG0673	inositol 2-dehydrogenase activity
WS08_0183	COG3842	ATPase activity
WS08_0184	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WS08_0185	COG1177	transmembrane transport
WS08_0186	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WS08_0187	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
WS08_0188	COG1950	PFAM Membrane protein of
WS08_0189	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
WS08_0190	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
WS08_0192	COG0492	ferredoxin-NADP+ reductase activity
WS08_0194	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WS08_0196	COG0149	triose-phosphate isomerase activity
WS08_0199	COG0557	exoribonuclease II activity
WS08_0200	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
WS08_0201	COG0765	amino acid transport
WS08_0202	COG1126	abc transporter atp-binding protein
WS08_0203	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
WS08_0204	COG0280	phosphate acetyltransferase
WS08_0205	COG0802	atpase or kinase
WS08_0208	COG0812	UDP-N-acetylmuramate dehydrogenase activity
WS08_0213	COG0540	Belongs to the ATCase OTCase family
WS08_0215	COG0505	Belongs to the CarA family
WS08_0216	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
WS08_0217	COG0284	orotidine-5'-phosphate decarboxylase activity
WS08_0218	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
WS08_0219	COG0438	transferase activity, transferring glycosyl groups
WS08_0220	COG0438	transferase activity, transferring glycosyl groups
WS08_0222	COG1368	sulfuric ester hydrolase activity
WS08_0223	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WS08_0223	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WS08_0224	COG0025	NhaP-type Na H and K H
WS08_0225	COG0084	hydrolase, TatD family'
WS08_0226	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
WS08_0227	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
WS08_0228	COG1253	flavin adenine dinucleotide binding
WS08_0229	COG4466	Protein conserved in bacteria
WS08_0230	COG2131	deaminase
WS08_0231	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
WS08_0232	COG1316	TRANSCRIPTIONal
WS08_0233	COG1983	PspC domain protein
WS08_0234	COG1968	undecaprenyl-diphosphatase activity
WS08_0235	COG1295	ribonuclease BN
WS08_0238	COG0193	aminoacyl-tRNA hydrolase activity
WS08_0239	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WS08_0240	COG2244	polysaccharide biosynthetic process
WS08_0241	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
WS08_0246	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
WS08_0247	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
WS08_0252	COG1271	oxidase subunit
WS08_0253	COG1294	oxidase, subunit
WS08_0254	COG4988	ABC transporter
WS08_0255	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
WS08_0256	COG1705	Flagellar rod assembly protein muramidase FlgJ
WS08_0262	COG1278	Cold shock
WS08_0263	COG0494	nUDIX hydrolase
WS08_0265	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WS08_0267	COG1388	LysM domain
WS08_0269	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
WS08_0270	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WS08_0271	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WS08_0273	COG4120	Belongs to the binding-protein-dependent transport system permease family
WS08_0274	COG1116	anion transmembrane transporter activity
WS08_0278	COG2003	Belongs to the UPF0758 family
WS08_0279	COG1077	Cell shape determining protein MreB Mrl
WS08_0283	COG0765	amino acid transport
WS08_0286	COG2759	Belongs to the formate--tetrahydrofolate ligase family
WS08_0291	COG0833	amino acid
WS08_0293	COG2264	protein methyltransferase activity
WS08_0294	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WS08_0295	COG2001	Belongs to the MraZ family
WS08_0296	COG0275	rRNA processing
WS08_0300	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
WS08_0301	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
WS08_0303	COG0849	cell division
WS08_0304	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
WS08_0305	COG1799	cell septum assembly
WS08_0306	COG0762	integral membrane protein
WS08_0307	COG2302	S4 RNA-binding domain
WS08_0308	COG3599	regulation of cell shape
WS08_0309	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
WS08_0312	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
WS08_0313	COG0217	transcriptional regulatory protein
WS08_0314	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WS08_0315	COG1459	type II secretion system
WS08_0316	COG4537	Required for transformation and DNA binding
WS08_0319	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
WS08_0320	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WS08_0321	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WS08_0321	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WS08_0323	COG2815	serine threonine protein kinase
WS08_0323	COG0515	serine threonine protein kinase
WS08_0324	COG1162	GTPase activity
WS08_0325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WS08_0327	COG0227	Belongs to the bacterial ribosomal protein bL28 family
WS08_0329	COG1461	Dihydroxyacetone kinase
WS08_0330	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WS08_0331	COG0416	fatty acid biosynthetic process
WS08_0332	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WS08_0333	COG0571	ribonuclease III activity
WS08_0334	COG1196	nuclear chromosome segregation
WS08_0335	COG0552	protein localization to endoplasmic reticulum
WS08_0337	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WS08_0338	COG0228	four-way junction DNA binding
WS08_0339	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
WS08_0340	COG0336	Belongs to the RNA methyltransferase TrmD family
WS08_0341	COG0335	large ribosomal subunit rRNA binding
WS08_0342	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WS08_0343	COG1942	4-Oxalocrotonate Tautomerase
WS08_0344	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
WS08_0345	COG0494	nUDIX hydrolase
WS08_0346	COG1428	Deoxynucleoside kinase
WS08_0348	COG0561	phosphatase activity
WS08_0353	COG4862	establishment of competence for transformation
WS08_0357	COG0006	proline dipeptidase activity
WS08_0358	COG1609	Transcriptional regulator
WS08_0362	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WS08_0363	COG3425	synthase
WS08_0365	COG0860	N-Acetylmuramoyl-L-alanine amidase
WS08_0366	COG0124	histidyl-tRNA synthetase
WS08_0367	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
WS08_0368	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WS08_0369	COG0828	Belongs to the bacterial ribosomal protein bS21 family
WS08_0370	COG1610	YqeY-like protein
WS08_0371	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
WS08_0372	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
WS08_0373	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
WS08_0374	COG1381	Involved in DNA repair and RecF pathway recombination
WS08_0375	COG0752	glycyl-tRNA synthetase alpha subunit
WS08_0376	COG0751	glycine-tRNA ligase activity
WS08_0379	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WS08_0380	COG1620	l-lactate permease
WS08_0383	COG2706	6-phosphogluconolactonase activity
WS08_0385	COG1674	ftsk spoiiie
WS08_0386	COG4152	abc transporter atp-binding protein
WS08_0387	COG1668	transmembrane transport
WS08_0388	COG0584	glycerophosphoryl diester phosphodiesterase
WS08_0390	COG0322	excinuclease ABC activity
WS08_0393	COG1739	Uncharacterized protein family UPF0029
WS08_0396	COG0632	four-way junction helicase activity
WS08_0397	COG2255	four-way junction helicase activity
WS08_0398	COG1862	Preprotein translocase
WS08_0399	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WS08_0400	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
WS08_0401	COG0513	Belongs to the DEAD box helicase family
WS08_0402	COG0110	maltose O-acetyltransferase activity
WS08_0403	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WS08_0406	COG3906	Belongs to the UPF0473 family
WS08_0407	COG3906	Belongs to the UPF0473 family
WS08_0408	COG1555	photosystem II stabilization
WS08_0409	COG2333	competence protein COMEC
WS08_0409	COG0658	competence protein
WS08_0410	COG1466	dna polymerase III delta subunit
WS08_0411	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
WS08_0412	COG0268	Binds directly to 16S ribosomal RNA
WS08_0419	COG0218	Necessary for normal cell division and for the maintenance of normal septation
WS08_0422	COG1193	negative regulation of DNA recombination
WS08_0424	COG3118	belongs to the thioredoxin family
WS08_0425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
WS08_0426	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
WS08_0428	COG2357	RelA SpoT domain protein
WS08_0429	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
WS08_0430	COG0564	pseudouridine synthase activity
WS08_0431	COG2239	Acts as a magnesium transporter
WS08_0432	COG0779	Required for maturation of 30S ribosomal subunits
WS08_0433	COG0195	Participates in both transcription termination and antitermination
WS08_0434	COG2740	Nucleic-acid-binding protein implicated in transcription termination
WS08_0436	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
WS08_0437	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
WS08_0438	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WS08_0439	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
WS08_0441	COG0196	riboflavin kinase activity
WS08_0443	COG3142	Participates in the control of copper homeostasis
WS08_0444	COG1307	EDD domain protein, DegV family
WS08_0445	COG1307	EDD domain protein, DegV family
WS08_0446	COG0277	FAD linked oxidase domain protein
WS08_0447	COG4479	Belongs to the UPF0346 family
WS08_0448	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
WS08_0449	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
WS08_0453	COG0758	DNA mediated transformation
WS08_0454	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
WS08_0455	COG4974	Belongs to the 'phage' integrase family
WS08_0458	COG2814	Major facilitator Superfamily
WS08_0460	COG0187	DNA topoisomerase II activity
WS08_0461	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
WS08_0465	COG1227	inorganic diphosphatase activity
WS08_0467	COG4175	Glycine betaine
WS08_0467	COG3448	diguanylate cyclase activity
WS08_0473	COG1011	Hydrolase
WS08_0479	COG0242	peptide deformylase activity
WS08_0480	COG4476	Belongs to the UPF0223 family
WS08_0481	COG0483	inositol monophosphate 1-phosphatase activity
WS08_0483	COG0772	Belongs to the SEDS family
WS08_0484	COG4471	UPF0298 protein
WS08_0485	COG0742	ribosomal rna small subunit methyltransferase
WS08_0486	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
WS08_0487	COG3480	Lon protease (S16) C-terminal proteolytic domain
WS08_0488	COG0477	Major facilitator Superfamily
WS08_0489	COG0358	DNA primase activity
WS08_0490	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WS08_0492	COG0745	RESPONSE REGULATOR receiver
WS08_0493	COG5002	protein histidine kinase activity
WS08_0494	COG0572	uridine kinase
WS08_0495	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WS08_0497	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WS08_0498	COG0670	Belongs to the BI1 family
WS08_0502	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
WS08_0503	COG0237	dephospho-CoA kinase activity
WS08_0505	COG1484	DNA-dependent DNA replication
WS08_0508	COG0745	RESPONSE REGULATOR receiver
WS08_0509	COG5002	protein histidine kinase activity
WS08_0511	COG0531	amino acid
WS08_0514	COG1686	Belongs to the peptidase S11 family
WS08_0515	COG0626	cystathionine gamma-synthase activity
WS08_0520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WS08_0522	COG0488	(ABC) transporter
WS08_0532	COG1304	FMN binding
WS08_0535	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WS08_0538	COG4690	dipeptidase activity
WS08_0539	COG1266	CAAX protease self-immunity
WS08_0555	COG1216	Glycosyl transferase, family 2
WS08_0556	COG1272	protein, Hemolysin III
WS08_0557	COG1268	BioY protein
WS08_0560	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
WS08_0561	COG0439	Biotin carboxylase
WS08_0562	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WS08_0564	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WS08_0566	COG0604	alcohol dehydrogenase
WS08_0566	COG3321	synthase
WS08_0569	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WS08_0571	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WS08_0572	COG2755	lipolytic protein G-D-S-L family
WS08_0572	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
WS08_0575	COG0446	pyridine nucleotide-disulphide oxidoreductase
WS08_0579	COG0352	thiamine-phosphate diphosphorylase activity
WS08_0580	COG0351	phosphomethylpyrimidine kinase
WS08_0581	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
WS08_0582	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
WS08_0584	COG0584	glycerophosphoryl diester phosphodiesterase
WS08_0587	COG0561	phosphatase activity
WS08_0588	COG3706	GGDEF domain
WS08_0591	COG0220	tRNA (guanine-N7-)-methyltransferase activity
WS08_0593	COG1131	(ABC) transporter
WS08_0594	COG0537	adenosine 5'-monophosphoramidase activity
WS08_0596	COG0556	nucleotide-excision repair
WS08_0599	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
WS08_0605	COG0116	Belongs to the methyltransferase superfamily
WS08_0606	COG3599	regulation of cell shape
WS08_0607	COG4474	Belongs to the UPF0398 family
WS08_0608	COG3331	DNA recombination
WS08_0611	COG3935	DnaD domain protein
WS08_0614	COG0017	Asparaginyl-tRNA synthetase
WS08_0616	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WS08_0616	COG1199	ATP-dependent helicase activity
WS08_0617	COG2261	transglycosylase associated protein
WS08_0632	COG1304	FMN binding
WS08_0633	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WS08_0634	COG0706	membrane insertase activity
WS08_0636	COG0105	UTP biosynthetic process
WS08_0638	COG0531	amino acid
WS08_0640	COG2855	membrane
WS08_0642	COG1215	transferase activity, transferring glycosyl groups
WS08_0644	COG0183	Belongs to the thiolase family
WS08_0646	COG0735	belongs to the Fur family
WS08_0648	COG0390	transport system, permease component
WS08_0649	COG4619	ABC transporter
WS08_0650	COG2267	carboxylic ester hydrolase activity
WS08_0651	COG2390	Transcriptional regulator
WS08_0653	COG1136	(ABC) transporter
WS08_0659	COG0095	Lipoate-protein ligase
WS08_0664	COG0741	lytic transglycosylase activity
WS08_0667	COG1694	Mazg nucleotide pyrophosphohydrolase
WS08_0668	COG1611	Belongs to the LOG family
WS08_0673	COG1609	Transcriptional regulator
WS08_0675	COG2759	Belongs to the formate--tetrahydrofolate ligase family
WS08_0676	COG0151	Belongs to the GarS family
WS08_0677	COG0138	bifunctional purine biosynthesis protein purh
WS08_0678	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WS08_0679	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
WS08_0681	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WS08_0682	COG0047	phosphoribosylformylglycinamidine synthase activity
WS08_0683	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WS08_0684	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
WS08_0685	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WS08_0686	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
WS08_0687	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
WS08_0688	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WS08_0689	COG1696	Membrane protein involved in D-alanine export
WS08_0693	COG0481	GTPase activity
WS08_0697	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
WS08_0698	COG3475	LICD family
WS08_0703	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
WS08_0704	COG0267	Belongs to the bacterial ribosomal protein bL33 family
WS08_0707	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
WS08_0708	COG2195	Cleaves the N-terminal amino acid of tripeptides
WS08_0709	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
WS08_0710	COG2384	SAM-dependent methyltransferase
WS08_0711	COG0457	Tetratricopeptide repeat
WS08_0717	COG2807	transmembrane transport
WS08_0718	COG4720	Psort location CytoplasmicMembrane, score
WS08_0719	COG0351	phosphomethylpyrimidine kinase
WS08_0721	COG1160	GTP binding
WS08_0722	COG0539	negative regulation of cytoplasmic translation
WS08_0723	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
WS08_0725	COG0514	ATP-dependent DNA helicase (RecQ)
WS08_0727	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
WS08_0728	COG1187	pseudouridine synthase activity
WS08_0729	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
WS08_0730	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
WS08_0731	COG0456	acetyltransferase
WS08_0733	COG2996	Protein conserved in bacteria
WS08_0735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WS08_0736	COG0149	triose-phosphate isomerase activity
WS08_0737	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
WS08_0739	COG3835	regulator
WS08_0740	COG0475	glutathione-regulated potassium exporter activity
WS08_0742	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WS08_0743	COG0587	DNA-directed DNA polymerase activity
WS08_0746	COG0488	(ABC) transporter
WS08_0747	COG0617	tRNA 3'-terminal CCA addition
WS08_0750	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WS08_0753	COG1316	TRANSCRIPTIONal
WS08_0756	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
WS08_0758	COG0052	Belongs to the universal ribosomal protein uS2 family
WS08_0759	COG2827	Endonuclease containing a URI domain
WS08_0760	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
WS08_0761	COG0204	Acyl-transferase
WS08_0762	COG3763	UPF0154 protein
WS08_0763	COG4224	UPF0291 protein
WS08_0764	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
WS08_0765	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
WS08_0765	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
WS08_0766	COG1234	tRNA 3'-trailer cleavage
WS08_0769	COG0484	heat shock protein binding
WS08_0770	COG0443	Heat shock 70 kDa protein
WS08_0771	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
WS08_0772	COG1420	regulation of RNA biosynthetic process
WS08_0775	COG0463	Glycosyl transferase, family 2
WS08_0778	COG0024	Methionine aminopeptidase
WS08_0780	COG1682	transport, permease protein
WS08_0781	COG1388	LysM domain
WS08_0781	COG1134	teichoic acid transport
WS08_0783	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
WS08_0784	COG2309	aminopeptidase activity
WS08_0785	COG1278	Cold shock
WS08_0787	COG2814	Major facilitator Superfamily
WS08_0788	COG1388	LysM domain
WS08_0789	COG1072	(Pantothenic acid kinase))
WS08_0790	COG3973	AAA domain
WS08_0791	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
WS08_0792	COG1546	Belongs to the CinA family
WS08_0792	COG1058	Belongs to the CinA family
WS08_0793	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WS08_0794	COG1426	Protein conserved in bacteria
WS08_0796	COG0612	Peptidase, M16
WS08_0797	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WS08_0801	COG1070	Carbohydrate kinase
WS08_0802	COG3481	metal-dependent phosphohydrolase, HD sub domain
WS08_0804	COG0420	3'-5' exonuclease activity
WS08_0806	COG3679	Belongs to the UPF0342 family
WS08_0807	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WS08_0808	COG1438	arginine binding
WS08_0809	COG0018	arginyl-trna synthetase
WS08_0812	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
WS08_0814	COG1597	lipid kinase activity
WS08_0815	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WS08_0818	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WS08_0818	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
WS08_0822	COG0667	Aldo Keto reductase
WS08_0823	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WS08_0824	COG0167	dihydroorotate dehydrogenase activity
WS08_0825	COG3859	Proton-coupled thiamine transporter YuaJ
WS08_0827	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
WS08_0828	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
WS08_0829	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
WS08_0830	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
WS08_0831	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
WS08_0832	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WS08_0834	COG3706	GGDEF domain
WS08_0836	COG4684	Psort location CytoplasmicMembrane, score
WS08_0837	COG0436	Aminotransferase
WS08_0839	COG0436	Aminotransferase
WS08_0841	COG1609	Transcriptional regulator
WS08_0846	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WS08_0846	COG1321	iron dependent repressor
WS08_0848	COG3764	Sortase (surface protein transpeptidase)
WS08_0849	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
WS08_0850	COG0513	Belongs to the DEAD box helicase family
WS08_0851	COG0673	inositol 2-dehydrogenase activity
WS08_0852	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WS08_0853	COG0501	Belongs to the peptidase M48B family
WS08_0854	COG1704	LemA family
WS08_0858	COG2153	protein acetylation
WS08_0862	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WS08_0863	COG0562	UDP-galactopyranose mutase
WS08_0864	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
WS08_0865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WS08_0867	COG0505	Belongs to the CarA family
WS08_0869	COG0564	pseudouridine synthase activity
WS08_0872	COG1113	amino acid transport
WS08_0875	COG0126	phosphoglycerate kinase activity
WS08_0880	COG0737	Belongs to the 5'-nucleotidase family
WS08_0889	COG3716	PTS system mannose fructose sorbose family IID component
WS08_0890	COG3715	PTS system
WS08_0895	COG1185	polyribonucleotide nucleotidyltransferase activity
WS08_0897	COG0586	Pfam SNARE associated Golgi protein
WS08_0898	COG1758	RNA polymerase activity
WS08_0899	COG0194	GDP metabolic process
WS08_0900	COG0497	DNA recombination
WS08_0901	COG1438	arginine binding
WS08_0902	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
WS08_0904	COG1722	exodeoxyribonuclease VII activity
WS08_0905	COG1570	exodeoxyribonuclease VII activity
WS08_0906	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
WS08_0907	COG4720	Psort location CytoplasmicMembrane, score
WS08_0910	COG0363	glucosamine-6-phosphate deaminase activity
WS08_0911	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WS08_0914	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
WS08_0916	COG1323	Belongs to the UPF0348 family
WS08_0918	COG0799	negative regulation of ribosome biogenesis
WS08_0919	COG1713	HD superfamily hydrolase involved in NAD metabolism
WS08_0920	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
WS08_0922	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
WS08_0923	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
WS08_0924	COG1181	Belongs to the D-alanine--D-alanine ligase family
WS08_0926	COG0531	amino acid
WS08_0927	COG0459	protein refolding
WS08_0928	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
WS08_0929	COG0488	(ABC) transporter
WS08_0930	COG0285	dihydrofolate synthase activity
WS08_0931	COG0525	valine-tRNA ligase activity
WS08_0932	COG1279	arginine transmembrane transporter activity
WS08_0933	COG0589	response to stress
WS08_0936	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WS08_0941	COG3557	Belongs to the UPF0374 family
WS08_0942	COG2137	regulation of response to DNA damage stimulus
WS08_0944	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
WS08_0946	COG0581	inorganic phosphate transmembrane transporter activity
WS08_0947	COG0573	inorganic phosphate transmembrane transporter activity
WS08_0948	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
WS08_0952	COG0393	Putative heavy-metal-binding
WS08_0953	COG0647	UMP catabolic process
WS08_0954	COG4470	Protein conserved in bacteria
WS08_0955	COG0737	Belongs to the 5'-nucleotidase family
WS08_0957	COG0006	proline dipeptidase activity
WS08_0959	COG0596	Alpha beta hydrolase
WS08_0960	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
WS08_0961	COG1169	isochorismate synthase
WS08_0964	COG0531	amino acid
WS08_0966	COG2814	Major facilitator Superfamily
WS08_0968	COG1063	alcohol dehydrogenase
WS08_0969	COG0813	purine-nucleoside phosphorylase activity
WS08_0970	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
WS08_0972	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WS08_0974	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WS08_0975	COG1447	Phosphotransferase system cellobiose-specific component IIA
WS08_0976	COG1120	ATPase activity
WS08_0982	COG1686	Belongs to the peptidase S11 family
WS08_0983	COG0211	Belongs to the bacterial ribosomal protein bL27 family
WS08_0984	COG0261	This protein binds to 23S rRNA in the presence of protein L20
WS08_0985	COG2271	Major facilitator Superfamily
WS08_0990	COG0174	glutamine synthetase
WS08_0991	COG0789	Transcriptional regulator
WS08_0992	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
WS08_0995	COG1940	carbohydrate kinase activity
WS08_0998	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
WS08_1001	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WS08_1002	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WS08_1003	COG0072	phenylalanine-tRNA ligase activity
WS08_1003	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WS08_1004	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
WS08_1005	COG1733	regulation of RNA biosynthetic process
WS08_1007	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WS08_1010	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
WS08_1011	COG0653	protein targeting
WS08_1014	COG0756	dUTP diphosphatase activity
WS08_1016	COG0791	NLP P60 protein
WS08_1018	COG0542	response to heat
WS08_1019	COG0604	alcohol dehydrogenase
WS08_1020	COG0028	Belongs to the TPP enzyme family
WS08_1021	COG3527	Alpha-acetolactate decarboxylase
WS08_1026	COG0333	Belongs to the bacterial ribosomal protein bL32 family
WS08_1029	COG0740	serine-type endopeptidase activity
WS08_1031	COG1481	regulation of sporulation
WS08_1032	COG0391	Required for morphogenesis under gluconeogenic growth conditions
WS08_1034	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
WS08_1041	COG0101	tRNA pseudouridine synthase activity
WS08_1043	COG1122	ATPase activity
WS08_1044	COG1122	ATPase activity
WS08_1045	COG3594	Acyltransferase
WS08_1048	COG0803	Belongs to the bacterial solute-binding protein 9 family
WS08_1049	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WS08_1050	COG1121	(ABC) transporter
WS08_1052	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WS08_1053	COG0222	ribosome binding
WS08_1054	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
WS08_1055	COG0081	regulation of translation
WS08_1056	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
WS08_1057	COG0250	Participates in transcription elongation, termination and antitermination
WS08_1058	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WS08_1061	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WS08_1062	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
WS08_1063	COG0215	cysteine-tRNA ligase activity
WS08_1066	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
WS08_1068	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WS08_1070	COG0203	ribosomal protein L17
WS08_1071	COG0202	RNA polymerase activity
WS08_1072	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
WS08_1073	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
WS08_1074	COG0257	Belongs to the bacterial ribosomal protein bL36 family
WS08_1075	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
WS08_1078	COG0200	Binds to the 23S rRNA
WS08_1079	COG1841	ribosomal large subunit assembly
WS08_1080	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
WS08_1081	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
WS08_1082	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
WS08_1083	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
WS08_1084	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
WS08_1085	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
WS08_1086	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
WS08_1088	COG0255	Belongs to the universal ribosomal protein uL29 family
WS08_1089	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
WS08_1090	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
WS08_1091	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
WS08_1092	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
WS08_1093	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
WS08_1094	COG0089	rRNA binding
WS08_1096	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
WS08_1097	COG0051	transcription antitermination factor activity, RNA binding
WS08_1102	COG1214	PFAM Peptidase M22, glycoprotease
WS08_1103	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WS08_1107	COG3870	Protein conserved in bacteria
WS08_1108	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
WS08_1110	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
WS08_1111	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
WS08_1112	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WS08_1114	COG2813	Specifically methylates the guanine in position
WS08_1121	COG1979	alcohol dehydrogenase
WS08_1122	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
WS08_1123	COG0085	RNA polymerase activity
WS08_1125	COG4463	regulation of RNA biosynthetic process
WS08_1126	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
WS08_1127	COG1428	Deoxynucleoside kinase
WS08_1129	COG1686	Belongs to the peptidase S11 family
WS08_1130	COG0355	proton-transporting ATP synthase activity, rotational mechanism
WS08_1131	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
WS08_1132	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
WS08_1133	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
WS08_1134	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WS08_1135	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
WS08_1136	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WS08_1137	COG0356	it plays a direct role in the translocation of protons across the membrane
WS08_1138	COG2233	PERMEase
WS08_1141	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
WS08_1142	COG0009	L-threonylcarbamoyladenylate synthase
WS08_1143	COG2890	protein-(glutamine-N5) methyltransferase activity
WS08_1144	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
WS08_1145	COG1435	thymidine kinase activity
WS08_1146	COG3442	glutamine amidotransferase
WS08_1147	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WS08_1148	COG1482	cell wall glycoprotein biosynthetic process
WS08_1152	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WS08_1157	COG1132	(ABC) transporter
WS08_1158	COG1132	(ABC) transporter
WS08_1160	COG0588	phosphoglycerate mutase activity
WS08_1161	COG1573	uracil-dna glycosylase
WS08_1162	COG2610	gluconate transmembrane transporter activity
WS08_1163	COG0708	Exodeoxyribonuclease III
WS08_1164	COG1454	alcohol dehydrogenase
WS08_1164	COG1012	belongs to the aldehyde dehydrogenase family
WS08_1165	COG2235	arginine
WS08_1166	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WS08_1167	COG0531	amino acid
WS08_1169	COG3590	peptidase
WS08_1172	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
WS08_1173	COG2188	Transcriptional regulator
WS08_1174	COG1418	mRNA catabolic process
WS08_1180	COG0488	(ABC) transporter
WS08_1182	COG1121	(ABC) transporter
WS08_1184	COG1846	Transcriptional regulator
WS08_1187	COG3104	oligopeptide transport
WS08_1189	COG5002	protein histidine kinase activity
WS08_1190	COG0745	RESPONSE REGULATOR receiver
WS08_1192	COG0012	GTP binding
WS08_1193	COG4481	Protein conserved in bacteria
WS08_1194	COG1475	DNA binding
WS08_1195	COG1192	Involved in chromosome partitioning
WS08_1196	COG0357	Ribosomal RNA small subunit methyltransferase G
WS08_1197	COG1194	a g-specific adenine glycosylase
WS08_1199	COG5002	protein histidine kinase activity
WS08_1200	COG0745	RESPONSE REGULATOR receiver
WS08_1201	COG0318	PFAM AMP-dependent synthetase and ligase
WS08_1202	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
WS08_1204	COG1335	isochorismatase
WS08_1206	COG4443	Transcriptional Coactivator p15 (PC4)
WS08_1207	COG0252	asparaginase activity
WS08_1208	COG0531	amino acid
WS08_1211	COG2130	NADP-dependent
WS08_1213	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WS08_1221	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
WS08_1224	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WS08_1225	COG1554	hydrolase, family 65, central catalytic
WS08_1226	COG1263	PTS System
WS08_1226	COG2190	(PTS) system
WS08_1226	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WS08_1227	COG1263	PTS System
WS08_1227	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WS08_1227	COG2190	(PTS) system
WS08_1228	COG2188	Transcriptional regulator
WS08_1229	COG1511	domain protein
WS08_1230	COG1959	2 iron, 2 sulfur cluster binding
WS08_1232	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WS08_1233	COG3620	sequence-specific DNA binding
WS08_1238	COG1113	amino acid transport
WS08_1239	COG0628	permease
WS08_1241	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WS08_1242	COG0765	amino acid transport
WS08_1243	COG1126	abc transporter atp-binding protein
WS08_1246	COG0640	Transcriptional regulator
WS08_1247	COG2217	Heavy metal translocating P-type atpase
WS08_1248	COG1309	transcriptional regulator
WS08_1249	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WS08_1250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WS08_1253	COG0028	Belongs to the TPP enzyme family
WS08_1255	COG4221	oxidoreductase activity
WS08_1256	COG0346	lactoylglutathione lyase activity
WS08_1257	COG0656	L-ascorbic acid biosynthetic process
WS08_1258	COG1733	regulation of RNA biosynthetic process
WS08_1259	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WS08_1263	COG0328	RNA-DNA hybrid ribonuclease activity
WS08_1264	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WS08_1265	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
WS08_1266	COG1113	amino acid transport
WS08_1267	COG0569	domain protein
WS08_1269	COG0706	membrane insertase activity
WS08_1270	COG0594	ribonuclease P activity