locus-tag	class	description
C6N67_00075	COG0629	single-stranded DNA binding
C6N67_00130	COG1783	phage Terminase large subunit
C6N67_00240	COG0588	phosphoglycerate mutase activity
C6N67_00245	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C6N67_00250	COG0336	Belongs to the RNA methyltransferase TrmD family
C6N67_00255	COG0335	large ribosomal subunit rRNA binding
C6N67_00265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C6N67_00270	COG1942	4-Oxalocrotonate Tautomerase
C6N67_00275	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C6N67_00285	COG1428	Deoxynucleoside kinase
C6N67_00290	COG1970	mechanosensitive ion channel activity
C6N67_00295	COG0561	phosphatase activity
C6N67_00360	COG3853	Toxic anion resistance protein (TelA)
C6N67_00365	COG1393	Belongs to the ArsC family
C6N67_00370	COG4862	establishment of competence for transformation
C6N67_00375	COG2723	6-phospho-beta-galactosidase activity
C6N67_00380	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6N67_00385	COG1447	Phosphotransferase system cellobiose-specific component IIA
C6N67_00390	COG2723	6-phospho-beta-galactosidase activity
C6N67_00395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6N67_00405	COG1164	Oligoendopeptidase f
C6N67_00410	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C6N67_00425	COG1609	Transcriptional regulator
C6N67_00430	COG0006	proline dipeptidase activity
C6N67_00505	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C6N67_00510	COG3425	synthase
C6N67_00525	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6N67_00530	COG0124	histidyl-tRNA synthetase
C6N67_00535	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C6N67_00545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C6N67_00550	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C6N67_00555	COG1610	YqeY-like protein
C6N67_00560	COG1702	phosphate starvation-inducible protein PhoH
C6N67_00565	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C6N67_00570	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C6N67_00575	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C6N67_00580	COG1381	Involved in DNA repair and RecF pathway recombination
C6N67_00590	COG0752	glycyl-tRNA synthetase alpha subunit
C6N67_00595	COG0751	glycine-tRNA ligase activity
C6N67_00615	COG2706	6-phosphogluconolactonase activity
C6N67_00620	COG0628	permease
C6N67_00630	COG1674	ftsk spoiiie
C6N67_00640	COG4152	abc transporter atp-binding protein
C6N67_00645	COG1668	transmembrane transport
C6N67_00655	COG0322	excinuclease ABC activity
C6N67_00660	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C6N67_00665	COG1739	Uncharacterized protein family UPF0029
C6N67_00685	COG0517	IMP dehydrogenase activity
C6N67_00685	COG0516	GMP reductase activity
C6N67_00690	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C6N67_00695	COG0632	four-way junction helicase activity
C6N67_00700	COG2255	four-way junction helicase activity
C6N67_00740	COG0343	queuine tRNA-ribosyltransferase activity
C6N67_00745	COG1862	Preprotein translocase
C6N67_00750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C6N67_00755	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C6N67_00760	COG0513	Belongs to the DEAD box helicase family
C6N67_00775	COG1929	Belongs to the glycerate kinase type-1 family
C6N67_00780	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C6N67_00800	COG3906	Belongs to the UPF0473 family
C6N67_00810	COG2333	competence protein COMEC
C6N67_00810	COG0658	competence protein
C6N67_00815	COG1466	dna polymerase III delta subunit
C6N67_00820	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C6N67_00825	COG0268	Binds directly to 16S ribosomal RNA
C6N67_00850	COG0544	peptidyl-prolyl cis-trans isomerase activity
C6N67_00855	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C6N67_00860	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C6N67_00880	COG1193	negative regulation of DNA recombination
C6N67_00900	COG3118	belongs to the thioredoxin family
C6N67_00905	COG0187	DNA topoisomerase II activity
C6N67_00910	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C6N67_00915	COG3527	Alpha-acetolactate decarboxylase
C6N67_00925	COG1473	amidohydrolase
C6N67_00940	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C6N67_00960	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C6N67_00965	COG3201	nicotinamide mononucleotide transporter
C6N67_01005	COG0028	Belongs to the TPP enzyme family
C6N67_01020	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C6N67_01035	COG2801	Transposase and inactivated derivatives
C6N67_01070	COG0277	FAD linked oxidase domain protein
C6N67_01075	COG0436	Aminotransferase
C6N67_01090	COG1464	Belongs to the NlpA lipoprotein family
C6N67_01100	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
C6N67_01105	COG0351	phosphomethylpyrimidine kinase
C6N67_01110	COG0352	thiamine-phosphate diphosphorylase activity
C6N67_01130	COG1028	Short-chain dehydrogenase reductase Sdr
C6N67_01140	COG1940	carbohydrate kinase activity
C6N67_01220	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C6N67_01225	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C6N67_01255	COG2801	Transposase and inactivated derivatives
C6N67_01260	COG5290	Psort location Cytoplasmic, score
C6N67_01270	COG2357	RelA SpoT domain protein
C6N67_01275	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C6N67_01280	COG0564	pseudouridine synthase activity
C6N67_01285	COG2239	Acts as a magnesium transporter
C6N67_01290	COG2814	Major facilitator Superfamily
C6N67_01350	COG0656	L-ascorbic acid biosynthetic process
C6N67_01355	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6N67_01365	COG1846	Transcriptional regulator
C6N67_01370	COG0456	acetyltransferase
C6N67_01435	COG4684	Psort location CytoplasmicMembrane, score
C6N67_01445	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C6N67_01455	COG0596	Alpha beta hydrolase
C6N67_01485	COG0384	phenazine biosynthesis protein PhzF
C6N67_01495	COG1621	beta-fructofuranosidase activity
C6N67_01515	COG2409	Drug exporters of the RND superfamily
C6N67_01515	COG1033	growth of symbiont in host cell
C6N67_01530	COG0583	DNA-binding transcription factor activity
C6N67_01550	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C6N67_01555	COG0287	Prephenate dehydrogenase
C6N67_01565	COG0738	Major facilitator superfamily
C6N67_01570	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C6N67_01590	COG1304	FMN binding
C6N67_01605	COG0779	Required for maturation of 30S ribosomal subunits
C6N67_01610	COG0195	Participates in both transcription termination and antitermination
C6N67_01615	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C6N67_01625	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C6N67_01630	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C6N67_01635	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C6N67_01640	COG1252	NADH dehydrogenase
C6N67_01650	COG0196	riboflavin kinase activity
C6N67_01660	COG3142	Participates in the control of copper homeostasis
C6N67_01675	COG2270	Major facilitator Superfamily
C6N67_01680	COG1307	EDD domain protein, DegV family
C6N67_01685	COG1307	EDD domain protein, DegV family
C6N67_01690	COG2755	lipolytic protein G-D-S-L family
C6N67_01700	COG4479	Belongs to the UPF0346 family
C6N67_01710	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C6N67_01715	COG0758	DNA mediated transformation
C6N67_01720	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C6N67_01725	COG4974	Belongs to the 'phage' integrase family
C6N67_01735	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C6N67_01740	COG1227	inorganic diphosphatase activity
C6N67_01755	COG3448	diguanylate cyclase activity
C6N67_01755	COG4175	Glycine betaine
C6N67_01770	COG1464	Belongs to the NlpA lipoprotein family
C6N67_01775	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C6N67_01780	COG1597	lipid kinase activity
C6N67_01785	COG1011	Hydrolase
C6N67_01820	COG0242	peptide deformylase activity
C6N67_01825	COG4476	Belongs to the UPF0223 family
C6N67_01830	COG0483	inositol monophosphate 1-phosphatase activity
C6N67_01840	COG0772	Belongs to the SEDS family
C6N67_01845	COG4471	UPF0298 protein
C6N67_01850	COG0742	ribosomal rna small subunit methyltransferase
C6N67_01855	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C6N67_01860	COG3480	Lon protease (S16) C-terminal proteolytic domain
C6N67_01865	COG0477	Major facilitator Superfamily
C6N67_01875	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C6N67_01880	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C6N67_01950	COG2801	Transposase and inactivated derivatives
C6N67_01970	COG0358	DNA primase activity
C6N67_01975	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C6N67_02005	COG0745	RESPONSE REGULATOR receiver
C6N67_02010	COG5002	protein histidine kinase activity
C6N67_02015	COG0572	uridine kinase
C6N67_02020	COG1363	Peptidase, m42
C6N67_02025	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6N67_02035	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C6N67_02040	COG0670	Belongs to the BI1 family
C6N67_02045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C6N67_02045	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C6N67_02050	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C6N67_02055	COG0237	dephospho-CoA kinase activity
C6N67_02065	COG1484	DNA-dependent DNA replication
C6N67_02080	COG0745	RESPONSE REGULATOR receiver
C6N67_02085	COG5002	protein histidine kinase activity
C6N67_02095	COG1705	Flagellar rod assembly protein muramidase FlgJ
C6N67_02095	COG3942	CHAP domain
C6N67_02105	COG2801	Transposase and inactivated derivatives
C6N67_02115	COG0531	amino acid
C6N67_02130	COG0706	membrane insertase activity
C6N67_02135	COG1028	Short-chain dehydrogenase reductase Sdr
C6N67_02140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C6N67_02150	COG1304	FMN binding
C6N67_02170	COG1199	ATP-dependent helicase activity
C6N67_02170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6N67_02180	COG0017	Asparaginyl-tRNA synthetase
C6N67_02185	COG3935	DnaD domain protein
C6N67_02195	COG3331	DNA recombination
C6N67_02200	COG4474	Belongs to the UPF0398 family
C6N67_02205	COG3599	regulation of cell shape
C6N67_02215	COG0116	Belongs to the methyltransferase superfamily
C6N67_02225	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C6N67_02245	COG0556	nucleotide-excision repair
C6N67_02255	COG0439	Biotin carboxylase
C6N67_02260	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C6N67_02270	COG3104	oligopeptide transport
C6N67_02275	COG0363	glucosamine-6-phosphate deaminase activity
C6N67_02285	COG0537	adenosine 5'-monophosphoramidase activity
C6N67_02290	COG1131	(ABC) transporter
C6N67_02300	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C6N67_02305	COG1719	4-vinyl reductase, 4VR
C6N67_02310	COG1397	ADP-ribosylglycohydrolase
C6N67_02340	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6N67_02345	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
C6N67_02350	COG1349	DNA-binding transcription factor activity
C6N67_02360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N67_02360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6N67_02360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6N67_02370	COG1609	Transcriptional regulator
C6N67_02380	COG0306	phosphate transporter
C6N67_02415	COG0531	amino acid
C6N67_02425	COG0481	GTPase activity
C6N67_02455	COG1028	Short-chain dehydrogenase reductase Sdr
C6N67_02460	COG4708	membrane
C6N67_02470	COG0531	amino acid
C6N67_02480	COG0583	DNA-binding transcription factor activity
C6N67_02495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6N67_02510	COG1136	(ABC) transporter
C6N67_02515	COG0577	efflux transmembrane transporter activity
C6N67_02535	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C6N67_02540	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C6N67_02560	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C6N67_02570	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C6N67_02575	COG2384	SAM-dependent methyltransferase
C6N67_02580	COG0071	Belongs to the small heat shock protein (HSP20) family
C6N67_02585	COG0457	Tetratricopeptide repeat
C6N67_02620	COG0419	ATPase involved in DNA repair
C6N67_02625	COG0420	3'-5' exonuclease activity
C6N67_02635	COG2807	transmembrane transport
C6N67_02640	COG4720	Psort location CytoplasmicMembrane, score
C6N67_02645	COG0351	phosphomethylpyrimidine kinase
C6N67_02655	COG1160	GTP binding
C6N67_02660	COG0539	negative regulation of cytoplasmic translation
C6N67_02665	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C6N67_02675	COG0514	ATP-dependent DNA helicase (RecQ)
C6N67_02685	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C6N67_02700	COG1187	pseudouridine synthase activity
C6N67_02705	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C6N67_02710	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C6N67_02725	COG2996	Protein conserved in bacteria
C6N67_02735	COG0475	glutathione-regulated potassium exporter activity
C6N67_02745	COG1490	D-aminoacyl-tRNA deacylase activity
C6N67_02750	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C6N67_02755	COG0587	DNA-directed DNA polymerase activity
C6N67_02765	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C6N67_02770	COG0488	(ABC) transporter
C6N67_02775	COG0617	tRNA 3'-terminal CCA addition
C6N67_02785	COG2801	Transposase and inactivated derivatives
C6N67_02805	COG1136	(ABC) transporter
C6N67_02815	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C6N67_02820	COG0004	ammonium transporteR
C6N67_02830	COG0366	Alpha amylase catalytic
C6N67_02830	COG5263	repeat protein
C6N67_02835	COG1316	TRANSCRIPTIONal
C6N67_02840	COG1216	Glycosyl transferase, family 2
C6N67_02855	COG1216	Glycosyl transferase, family 2
C6N67_02865	COG0438	transferase activity, transferring glycosyl groups
C6N67_02870	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C6N67_02875	COG0489	protein tyrosine kinase activity
C6N67_02890	COG0233	cytoplasmic translational termination
C6N67_02900	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C6N67_02905	COG0052	Belongs to the universal ribosomal protein uS2 family
C6N67_02910	COG2827	Endonuclease containing a URI domain
C6N67_02915	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C6N67_02920	COG0204	Acyl-transferase
C6N67_02925	COG3883	PFAM NLP P60 protein
C6N67_02925	COG0791	NLP P60 protein
C6N67_02940	COG3763	UPF0154 protein
C6N67_02945	COG4224	UPF0291 protein
C6N67_02950	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C6N67_02970	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C6N67_02970	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C6N67_02975	COG1234	tRNA 3'-trailer cleavage
C6N67_02990	COG0484	heat shock protein binding
C6N67_02995	COG0443	Heat shock 70 kDa protein
C6N67_03005	COG1420	regulation of RNA biosynthetic process
C6N67_03035	COG1216	Glycosyl transferase, family 2
C6N67_03045	COG0463	Glycosyl transferase, family 2
C6N67_03055	COG1705	Flagellar rod assembly protein muramidase FlgJ
C6N67_03070	COG0562	UDP-galactopyranose mutase
C6N67_03095	COG0024	Methionine aminopeptidase
C6N67_03115	COG1388	LysM domain
C6N67_03115	COG1705	Flagellar rod assembly protein muramidase FlgJ
C6N67_03150	COG1682	transport, permease protein
C6N67_03155	COG1388	LysM domain
C6N67_03155	COG1134	teichoic acid transport
C6N67_03160	COG0463	Glycosyl transferase, family 2
C6N67_03160	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C6N67_03165	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C6N67_03165	COG0463	Glycosyl transferase, family 2
C6N67_03170	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C6N67_03190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6N67_03240	COG3883	PFAM NLP P60 protein
C6N67_03240	COG0791	NLP P60 protein
C6N67_03335	COG2199	diguanylate cyclase activity
C6N67_03345	COG2801	Transposase and inactivated derivatives
C6N67_03380	COG2309	aminopeptidase activity
C6N67_03395	COG0564	pseudouridine synthase activity
C6N67_03400	COG1278	Cold shock
C6N67_03410	COG2814	Major facilitator Superfamily
C6N67_03415	COG0741	lytic transglycosylase activity
C6N67_03425	COG3973	AAA domain
C6N67_03435	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C6N67_03440	COG1058	Belongs to the CinA family
C6N67_03440	COG1546	Belongs to the CinA family
C6N67_03445	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C6N67_03450	COG1426	Protein conserved in bacteria
C6N67_03455	COG0612	Peptidase, M16
C6N67_03460	COG0612	Peptidase, M16
C6N67_03475	COG0028	Belongs to the TPP enzyme family
C6N67_03495	COG4717	serine-type aminopeptidase activity
C6N67_03515	COG3679	Belongs to the UPF0342 family
C6N67_03520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C6N67_03525	COG1438	arginine binding
C6N67_03545	COG0018	arginyl-trna synthetase
C6N67_03560	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C6N67_03570	COG1121	(ABC) transporter
C6N67_03585	COG2826	transposase and inactivated derivatives, IS30 family
C6N67_03595	COG1597	lipid kinase activity
C6N67_03600	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C6N67_03605	COG0154	amidase activity
C6N67_03610	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C6N67_03615	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C6N67_03615	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
C6N67_03640	COG1695	Transcriptional regulator
C6N67_03650	COG1914	H( )-stimulated, divalent metal cation uptake system
C6N67_03670	COG0667	Aldo Keto reductase
C6N67_03675	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C6N67_03680	COG4721	ABC-type cobalt transport system, permease component
C6N67_03685	COG1122	ATPase activity
C6N67_03700	COG0710	3-dehydroquinate dehydratase activity
C6N67_03705	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C6N67_03710	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C6N67_03715	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C6N67_03720	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C6N67_03725	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C6N67_03730	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C6N67_03745	COG4684	Psort location CytoplasmicMembrane, score
C6N67_03750	COG0436	Aminotransferase
C6N67_03765	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C6N67_03770	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C6N67_03775	COG0436	Aminotransferase
C6N67_03780	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C6N67_03785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C6N67_03795	COG2171	N-acyltransferase activity
C6N67_03805	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C6N67_03810	COG0527	aspartate kinase activity
C6N67_03820	COG1609	Transcriptional regulator
C6N67_03825	COG0083	homoserine kinase activity
C6N67_03840	COG1321	iron dependent repressor
C6N67_03845	COG3764	Sortase (surface protein transpeptidase)
C6N67_03865	COG0513	Belongs to the DEAD box helicase family
C6N67_03870	COG0673	inositol 2-dehydrogenase activity
C6N67_03875	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C6N67_03885	COG0501	Belongs to the peptidase M48B family
C6N67_03890	COG1704	LemA family
C6N67_03900	COG4115	mRNA cleavage
C6N67_03905	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C6N67_03920	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C6N67_03930	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C6N67_03935	COG0439	Biotin carboxylase
C6N67_03950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C6N67_03955	COG1028	Short-chain dehydrogenase reductase Sdr
C6N67_03960	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C6N67_03965	COG2070	2-Nitropropane dioxygenase
C6N67_03970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C6N67_03975	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C6N67_03980	COG1846	Transcriptional regulator
C6N67_03985	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C6N67_03995	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C6N67_04000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6N67_04010	COG0505	Belongs to the CarA family
C6N67_04020	COG0564	pseudouridine synthase activity
C6N67_04030	COG0328	RNA-DNA hybrid ribonuclease activity
C6N67_04040	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C6N67_04045	COG1113	amino acid transport
C6N67_04190	COG2801	Transposase and inactivated derivatives
C6N67_04205	COG1396	sequence-specific DNA binding
C6N67_04225	COG4974	Belongs to the 'phage' integrase family
C6N67_04250	COG1454	alcohol dehydrogenase
C6N67_04250	COG1012	belongs to the aldehyde dehydrogenase family
C6N67_04255	COG0105	UTP biosynthetic process
C6N67_04265	COG0583	DNA-binding transcription factor activity
C6N67_04270	COG0126	phosphoglycerate kinase activity
C6N67_04320	COG0588	phosphoglycerate mutase activity
C6N67_04330	COG3716	PTS system mannose fructose sorbose family IID component
C6N67_04335	COG3715	PTS system
C6N67_04350	COG1397	ADP-ribosylglycohydrolase
C6N67_04410	COG1368	sulfuric ester hydrolase activity
C6N67_04425	COG0438	transferase activity, transferring glycosyl groups
C6N67_04430	COG0438	transferase activity, transferring glycosyl groups
C6N67_04435	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C6N67_04440	COG0284	orotidine-5'-phosphate decarboxylase activity
C6N67_04445	COG0167	dihydroorotate dehydrogenase activity
C6N67_04450	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C6N67_04460	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C6N67_04465	COG0540	Belongs to the ATCase OTCase family
C6N67_04485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C6N67_04490	COG4856	YbbR-like protein
C6N67_04505	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C6N67_04520	COG0802	atpase or kinase
C6N67_04525	COG0280	phosphate acetyltransferase
C6N67_04540	COG2076	Multidrug Resistance protein
C6N67_04545	COG2076	Multidrug Resistance protein
C6N67_04550	COG1126	abc transporter atp-binding protein
C6N67_04555	COG0765	amino acid transport
C6N67_04575	COG0557	exoribonuclease II activity
C6N67_04590	COG0154	amidase activity
C6N67_04610	COG0149	triose-phosphate isomerase activity
C6N67_04615	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C6N67_04620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N67_04630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C6N67_04635	COG0492	ferredoxin-NADP+ reductase activity
C6N67_04665	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C6N67_04670	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C6N67_04675	COG1950	PFAM Membrane protein of
C6N67_04685	COG0589	response to stress
C6N67_04695	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C6N67_04705	COG1177	transmembrane transport
C6N67_04710	COG1176	ABC-type spermidine putrescine transport system, permease component I
C6N67_04715	COG3842	ATPase activity
C6N67_04725	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C6N67_04730	COG0049	tRNA binding
C6N67_04735	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C6N67_04750	COG4608	Belongs to the ABC transporter superfamily
C6N67_04755	COG0444	Belongs to the ABC transporter superfamily
C6N67_04760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6N67_04765	COG0601	transmembrane transport
C6N67_04775	COG0460	homoserine dehydrogenase
C6N67_04780	COG0626	cystathionine gamma-synthase activity
C6N67_04785	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C6N67_04800	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C6N67_04805	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C6N67_04820	COG1302	Protein conserved in bacteria
C6N67_04825	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C6N67_04835	COG2017	converts alpha-aldose to the beta-anomer
C6N67_04845	COG4975	Glucose uptake
C6N67_04850	COG5002	protein histidine kinase activity
C6N67_04850	COG3850	Histidine kinase
C6N67_04855	COG0745	RESPONSE REGULATOR receiver
C6N67_04860	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C6N67_04865	COG0402	S-adenosylhomocysteine deaminase activity
C6N67_04870	COG0673	inositol 2-dehydrogenase activity
C6N67_04895	COG0668	transmembrane transport
C6N67_04905	COG1126	abc transporter atp-binding protein
C6N67_04940	COG0516	GMP reductase activity
C6N67_05005	COG0494	nUDIX hydrolase
C6N67_05040	COG0738	Major facilitator superfamily
C6N67_05045	COG1869	D-ribose catabolic process
C6N67_05050	COG1609	Transcriptional regulator
C6N67_05070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6N67_05085	COG1609	Transcriptional regulator
C6N67_05105	COG2223	nitrite transmembrane transporter activity
C6N67_05125	COG1116	anion transmembrane transporter activity
C6N67_05130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6N67_05140	COG0285	dihydrofolate synthase activity
C6N67_05145	COG0302	gtp cyclohydrolase
C6N67_05150	COG0302	gtp cyclohydrolase
C6N67_05150	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C6N67_05165	COG0561	phosphatase activity
C6N67_05185	COG1464	Belongs to the NlpA lipoprotein family
C6N67_05190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6N67_05195	COG0800	Aldolase
C6N67_05200	COG1904	glucuronate isomerase
C6N67_05205	COG1312	Catalyzes the dehydration of D-mannonate
C6N67_05210	COG0246	Mannitol dehydrogenase
C6N67_05225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6N67_05240	COG1609	Transcriptional regulator
C6N67_05270	COG0577	efflux transmembrane transporter activity
C6N67_05275	COG1136	(ABC) transporter
C6N67_05280	COG3759	membrane
C6N67_05300	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C6N67_05305	COG2235	arginine
C6N67_05315	COG2217	Heavy metal translocating P-type atpase
C6N67_05370	COG0438	transferase activity, transferring glycosyl groups
C6N67_05425	COG2814	Major facilitator Superfamily
C6N67_05430	COG2217	Heavy metal translocating P-type atpase
C6N67_05470	COG3711	transcriptional antiterminator
C6N67_05475	COG2723	6-phospho-beta-galactosidase activity
C6N67_05480	COG1940	carbohydrate kinase activity
C6N67_05505	COG2183	response to ionizing radiation
C6N67_05520	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C6N67_05525	COG1040	competence protein
C6N67_05530	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C6N67_05535	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C6N67_05610	COG2176	DNA-directed DNA polymerase activity
C6N67_05615	COG0442	prolyl-tRNA aminoacylation
C6N67_05620	COG0750	zinc metalloprotease
C6N67_05625	COG4589	Belongs to the CDS family
C6N67_05630	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C6N67_05635	COG0561	phosphatase activity
C6N67_05640	COG2246	polysaccharide biosynthetic process
C6N67_05665	COG1811	Na channel or pump
C6N67_05670	COG1979	alcohol dehydrogenase
C6N67_05685	COG0517	IMP dehydrogenase activity
C6N67_05685	COG1125	glycine betaine transport
C6N67_05690	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C6N67_05700	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C6N67_05710	COG0307	riboflavin synthase, alpha
C6N67_05715	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6N67_05715	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6N67_05720	COG2076	Multidrug Resistance protein
C6N67_05725	COG2076	Multidrug Resistance protein
C6N67_05730	COG1435	thymidine kinase activity
C6N67_05750	COG0656	L-ascorbic acid biosynthetic process
C6N67_05755	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C6N67_05780	COG4166	transmembrane transport
C6N67_05830	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C6N67_05840	COG2252	PERMEase
C6N67_05850	COG0352	thiamine-phosphate diphosphorylase activity
C6N67_05855	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
C6N67_05870	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C6N67_05890	COG0577	efflux transmembrane transporter activity
C6N67_05890	COG1136	(ABC) transporter
C6N67_05900	COG0561	phosphatase activity
C6N67_05905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C6N67_05905	COG2169	Transcriptional regulator
C6N67_05910	COG0561	phosphatase activity
C6N67_05930	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C6N67_05935	COG0772	Belongs to the SEDS family
C6N67_05945	COG1077	Cell shape determining protein MreB Mrl
C6N67_05950	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C6N67_05975	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6N67_05985	COG0640	Transcriptional regulator
C6N67_05990	COG0628	permease
C6N67_05995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C6N67_06015	COG0386	Belongs to the glutathione peroxidase family
C6N67_06020	COG2357	RelA SpoT domain protein
C6N67_06025	COG0588	phosphoglycerate mutase activity
C6N67_06035	COG0492	ferredoxin-NADP+ reductase activity
C6N67_06050	COG1744	ABC transporter substrate-binding protein PnrA-like
C6N67_06065	COG2832	Protein of unknown function (DUF454)
C6N67_06090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C6N67_06100	COG2814	Major facilitator Superfamily
C6N67_06105	COG0305	Participates in initiation and elongation during chromosome replication
C6N67_06110	COG0359	binds to the 23S rRNA
C6N67_06120	COG4608	Belongs to the ABC transporter superfamily
C6N67_06125	COG0444	Belongs to the ABC transporter superfamily
C6N67_06130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6N67_06135	COG0601	transmembrane transport
C6N67_06140	COG4166	transmembrane transport
C6N67_06145	COG0765	amino acid transport
C6N67_06150	COG0765	amino acid transport
C6N67_06155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N67_06175	COG0194	GDP metabolic process
C6N67_06180	COG1268	BioY protein
C6N67_06210	COG2211	Major facilitator Superfamily
C6N67_06215	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C6N67_06230	COG3973	AAA domain
C6N67_06255	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C6N67_06265	COG1696	Membrane protein involved in D-alanine export
C6N67_06285	COG2337	Toxic component of a toxin-antitoxin (TA) module
C6N67_06300	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C6N67_06305	COG0504	CTP synthase activity
C6N67_06315	COG3343	RNA polymerase activity
C6N67_06320	COG0561	phosphatase activity
C6N67_06325	COG1078	dGTPase activity
C6N67_06335	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6N67_06340	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C6N67_06360	COG0745	RESPONSE REGULATOR receiver
C6N67_06385	COG2826	transposase and inactivated derivatives, IS30 family
C6N67_06395	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C6N67_06400	COG0629	single-stranded DNA binding
C6N67_06405	COG0360	Binds together with S18 to 16S ribosomal RNA
C6N67_06415	COG1957	nucleoside hydrolase
C6N67_06420	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C6N67_06430	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C6N67_06435	COG1051	belongs to the nudix hydrolase family
C6N67_06450	COG2814	Major facilitator Superfamily
C6N67_06455	COG1064	alcohol dehydrogenase
C6N67_06460	COG1074	ATP-dependent DNA helicase activity
C6N67_06465	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
C6N67_06480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C6N67_06485	COG2197	response regulator
C6N67_06490	COG4585	Histidine kinase
C6N67_06500	COG2409	Drug exporters of the RND superfamily
C6N67_06505	COG2801	Transposase and inactivated derivatives
C6N67_06515	COG2409	Drug exporters of the RND superfamily
C6N67_06520	COG0531	amino acid
C6N67_06525	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C6N67_06535	COG1902	pentaerythritol trinitrate reductase activity
C6N67_06540	COG0626	cystathionine gamma-synthase activity
C6N67_06555	COG2244	polysaccharide biosynthetic process
C6N67_06565	COG0438	transferase activity, transferring glycosyl groups
C6N67_06570	COG0495	leucyl-tRNA aminoacylation
C6N67_06575	COG0671	phosphoesterase, PA-phosphatase related
C6N67_06585	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C6N67_06610	COG2723	6-phospho-beta-galactosidase activity
C6N67_06635	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C6N67_06650	COG0024	Methionine aminopeptidase
C6N67_06660	COG1316	TRANSCRIPTIONal
C6N67_06670	COG2205	protein histidine kinase activity
C6N67_06675	COG0745	RESPONSE REGULATOR receiver
C6N67_06680	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C6N67_06695	COG2207	Transcriptional regulator
C6N67_06715	COG0308	aminopeptidase N
C6N67_06720	COG0833	amino acid
C6N67_06725	COG2040	homocysteine
C6N67_06730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N67_06735	COG0542	response to heat
C6N67_06750	COG0395	ABC-type sugar transport system, permease component
C6N67_06755	COG1175	transmembrane transport
C6N67_06805	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C6N67_06815	COG0107	imidazoleglycerol-phosphate synthase activity
C6N67_06820	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C6N67_06830	COG0131	Imidazoleglycerol-phosphate dehydratase
C6N67_06835	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C6N67_06845	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C6N67_06965	COG0438	transferase activity, transferring glycosyl groups
C6N67_06990	COG2084	Dehydrogenase
C6N67_06995	COG1028	Short-chain dehydrogenase reductase Sdr
C6N67_07005	COG1620	l-lactate permease
C6N67_07010	COG4989	oxidoreductase activity
C6N67_07015	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C6N67_07020	COG2233	PERMEase
C6N67_07035	COG1956	GAF domain-containing protein
C6N67_07060	COG0747	negative chemotaxis
C6N67_07065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6N67_07070	COG0601	transmembrane transport
C6N67_07075	COG4608	Belongs to the ABC transporter superfamily
C6N67_07080	COG0444	Belongs to the ABC transporter superfamily
C6N67_07090	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C6N67_07095	COG2211	Major facilitator Superfamily
C6N67_07095	COG2190	(PTS) system
C6N67_07115	COG0436	Aminotransferase
C6N67_07125	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6N67_07130	COG2801	Transposase and inactivated derivatives
C6N67_07140	COG2723	6-phospho-beta-galactosidase activity
C6N67_07145	COG2723	6-phospho-beta-galactosidase activity
C6N67_07150	COG1447	Phosphotransferase system cellobiose-specific component IIA
C6N67_07155	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6N67_07160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C6N67_07165	COG1216	Glycosyl transferase, family 2
C6N67_07180	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C6N67_07240	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C6N67_07245	COG1737	Transcriptional regulator
C6N67_07255	COG0656	L-ascorbic acid biosynthetic process
C6N67_07260	COG2261	transglycosylase associated protein
C6N67_07325	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C6N67_07345	COG0037	tRNA processing
C6N67_07355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C6N67_07360	COG2244	polysaccharide biosynthetic process
C6N67_07365	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C6N67_07370	COG0193	aminoacyl-tRNA hydrolase activity
C6N67_07380	COG0058	SHG alpha-glucan phosphorylase activity
C6N67_07385	COG0297	glycogen (starch) synthase activity
C6N67_07390	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C6N67_07400	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C6N67_07405	COG1511	domain protein
C6N67_07405	COG1511	domain protein
C6N67_07410	COG1309	transcriptional regulator
C6N67_07425	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6N67_07430	COG0477	Major facilitator Superfamily
C6N67_07445	COG0667	Aldo Keto reductase
C6N67_07455	COG2115	Belongs to the xylose isomerase family
C6N67_07465	COG2211	Major facilitator Superfamily
C6N67_07470	COG3507	Belongs to the glycosyl hydrolase 43 family
C6N67_07495	COG2818	Glycosylase
C6N67_07500	COG1968	undecaprenyl-diphosphatase activity
C6N67_07515	COG1695	Transcriptional regulator
C6N67_07520	COG1983	PspC domain protein
C6N67_07525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6N67_07530	COG0737	Belongs to the 5'-nucleotidase family
C6N67_07545	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
C6N67_07555	COG2723	6-phospho-beta-galactosidase activity
C6N67_07565	COG1316	TRANSCRIPTIONal
C6N67_07570	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C6N67_07575	COG2131	deaminase
C6N67_07580	COG4466	Protein conserved in bacteria
C6N67_07585	COG1253	flavin adenine dinucleotide binding
C6N67_07590	COG1253	flavin adenine dinucleotide binding
C6N67_07595	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C6N67_07600	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C6N67_07605	COG0084	hydrolase, TatD family'
C6N67_07615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6N67_07615	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6N67_07635	COG2826	transposase and inactivated derivatives, IS30 family
C6N67_07680	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C6N67_07700	COG1368	sulfuric ester hydrolase activity
C6N67_07705	COG2153	protein acetylation
C6N67_07720	COG0187	DNA topoisomerase II activity
C6N67_07725	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C6N67_07730	COG2501	S4 domain
C6N67_07735	COG0592	DNA-directed DNA polymerase activity
C6N67_07740	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C6N67_07745	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C6N67_07750	COG0594	ribonuclease P activity
C6N67_07755	COG0706	membrane insertase activity
C6N67_07765	COG1120	ATPase activity
C6N67_07775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C6N67_07790	COG0569	domain protein
C6N67_07795	COG1113	amino acid transport
C6N67_07815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6N67_07825	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6N67_07835	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C6N67_07840	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C6N67_07850	COG1136	(ABC) transporter
C6N67_07855	COG0577	efflux transmembrane transporter activity
C6N67_07860	COG2409	Drug exporters of the RND superfamily
C6N67_07860	COG1033	growth of symbiont in host cell
C6N67_07865	COG0561	phosphatase activity
C6N67_07875	COG0328	RNA-DNA hybrid ribonuclease activity
C6N67_07895	COG3152	Membrane
C6N67_07900	COG2252	PERMEase
C6N67_07940	COG1881	PFAM PEBP family protein
C6N67_07960	COG1476	TRANSCRIPTIONal
C6N67_08015	COG0697	spore germination
C6N67_08030	COG1874	Beta-galactosidase
C6N67_08045	COG0561	phosphatase activity
C6N67_08055	COG1744	ABC transporter substrate-binding protein PnrA-like
C6N67_08060	COG0137	argininosuccinate synthase activity
C6N67_08065	COG0165	Argininosuccinate lyase
C6N67_08070	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C6N67_08075	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C6N67_08090	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C6N67_08095	COG0505	Belongs to the CarA family
C6N67_08100	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C6N67_08120	COG1131	(ABC) transporter
C6N67_08145	COG0789	Transcriptional regulator
C6N67_08150	COG1028	Short-chain dehydrogenase reductase Sdr
C6N67_08160	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C6N67_08170	COG0697	spore germination
C6N67_08175	COG1744	ABC transporter substrate-binding protein PnrA-like
C6N67_08195	COG1846	Transcriptional regulator
C6N67_08210	COG0656	L-ascorbic acid biosynthetic process
C6N67_08220	COG4619	ABC transporter
C6N67_08225	COG0390	transport system, permease component
C6N67_08235	COG1131	(ABC) transporter
C6N67_08245	COG1126	abc transporter atp-binding protein
C6N67_08250	COG0765	amino acid transport
C6N67_08255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N67_08260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N67_08265	COG1254	Belongs to the acylphosphatase family
C6N67_08275	COG0392	lysyltransferase activity
C6N67_08275	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C6N67_08285	COG0628	permease
C6N67_08315	COG1113	amino acid transport
C6N67_08340	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6N67_08345	COG0454	-acetyltransferase
C6N67_08345	COG0456	acetyltransferase
C6N67_08355	COG2855	membrane
C6N67_08360	COG3620	sequence-specific DNA binding
C6N67_08370	COG2855	membrane
C6N67_08375	COG0583	DNA-binding transcription factor activity
C6N67_08385	COG2070	2-Nitropropane dioxygenase
C6N67_08400	COG1228	amidohydrolase
C6N67_08405	COG0531	amino acid
C6N67_08415	COG3223	Belongs to the PsiE family
C6N67_08425	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C6N67_08435	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C6N67_08445	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C6N67_08450	COG4166	transmembrane transport
C6N67_08455	COG2267	carboxylic ester hydrolase activity
C6N67_08460	COG1131	(ABC) transporter
C6N67_08480	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C6N67_08490	COG0477	Major facilitator Superfamily
C6N67_08495	COG4975	Glucose uptake
C6N67_08510	COG0531	amino acid
C6N67_08515	COG1113	amino acid transport
C6N67_08520	COG0531	amino acid
C6N67_08525	COG0252	asparaginase activity
C6N67_08530	COG4443	Transcriptional Coactivator p15 (PC4)
C6N67_08540	COG2226	methyltransferase
C6N67_08545	COG1335	isochorismatase
C6N67_08550	COG2050	protein possibly involved in aromatic compounds catabolism
C6N67_08555	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C6N67_08560	COG0318	PFAM AMP-dependent synthetase and ligase
C6N67_08575	COG0745	RESPONSE REGULATOR receiver
C6N67_08580	COG5002	protein histidine kinase activity
C6N67_08620	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C6N67_08625	COG1194	a g-specific adenine glycosylase
C6N67_08635	COG0357	Ribosomal RNA small subunit methyltransferase G
C6N67_08640	COG1192	Involved in chromosome partitioning
C6N67_08645	COG1475	DNA binding
C6N67_08650	COG4481	Protein conserved in bacteria
C6N67_08655	COG0012	GTP binding
C6N67_08665	COG0745	RESPONSE REGULATOR receiver
C6N67_08675	COG1686	Belongs to the peptidase S11 family
C6N67_08725	COG3104	oligopeptide transport
C6N67_08730	COG0477	Major facilitator Superfamily
C6N67_08735	COG4975	Glucose uptake
C6N67_08785	COG2755	lipolytic protein G-D-S-L family
C6N67_08785	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C6N67_08790	COG1846	Transcriptional regulator
C6N67_08800	COG1121	(ABC) transporter
C6N67_08805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C6N67_08810	COG1373	ATPase (AAA superfamily
C6N67_08815	COG0488	(ABC) transporter
C6N67_08820	COG0534	Mate efflux family protein
C6N67_08835	COG3940	Belongs to the glycosyl hydrolase 43 family
C6N67_08855	COG2160	L-arabinose isomerase activity
C6N67_08860	COG0656	L-ascorbic acid biosynthetic process
C6N67_08890	COG0765	amino acid transport
C6N67_08925	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C6N67_08930	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C6N67_08945	COG1418	mRNA catabolic process
C6N67_08950	COG2814	Major facilitator Superfamily
C6N67_08960	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C6N67_08965	COG2188	Transcriptional regulator
C6N67_08970	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
C6N67_08985	COG5039	Polysaccharide pyruvyl transferase
C6N67_08995	COG2801	Transposase and inactivated derivatives
C6N67_09050	COG3590	peptidase
C6N67_09055	COG1454	alcohol dehydrogenase
C6N67_09055	COG1012	belongs to the aldehyde dehydrogenase family
C6N67_09065	COG0708	Exodeoxyribonuclease III
C6N67_09085	COG0588	phosphoglycerate mutase activity
C6N67_09105	COG1132	(ABC) transporter
C6N67_09110	COG1132	(ABC) transporter
C6N67_09115	COG1373	ATPase (AAA superfamily
C6N67_09140	COG0110	maltose O-acetyltransferase activity
C6N67_09150	COG1482	cell wall glycoprotein biosynthetic process
C6N67_09155	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C6N67_09160	COG3442	glutamine amidotransferase
C6N67_09170	COG1435	thymidine kinase activity
C6N67_09175	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C6N67_09180	COG2890	protein-(glutamine-N5) methyltransferase activity
C6N67_09190	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C6N67_09195	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C6N67_09200	COG0702	epimerase
C6N67_09210	COG2233	PERMEase
C6N67_09215	COG0356	it plays a direct role in the translocation of protons across the membrane
C6N67_09220	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C6N67_09225	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C6N67_09230	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C6N67_09235	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C6N67_09240	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C6N67_09245	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C6N67_09250	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C6N67_09255	COG1876	peptidase activity
C6N67_09260	COG1428	Deoxynucleoside kinase
C6N67_09265	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C6N67_09290	COG4463	regulation of RNA biosynthetic process
C6N67_09295	COG0542	response to heat
C6N67_09300	COG0085	RNA polymerase activity
C6N67_09320	COG1979	alcohol dehydrogenase
C6N67_09355	COG1309	transcriptional regulator
C6N67_09360	COG0500	methyltransferase
C6N67_09405	COG3620	sequence-specific DNA binding
C6N67_09415	COG2807	transmembrane transport
C6N67_09425	COG2813	Specifically methylates the guanine in position
C6N67_09430	COG0590	tRNA wobble adenosine to inosine editing
C6N67_09440	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C6N67_09465	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C6N67_09470	COG3870	Protein conserved in bacteria
C6N67_09490	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C6N67_09495	COG1214	PFAM Peptidase M22, glycoprotease
C6N67_09500	COG0456	acetyltransferase
C6N67_09510	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C6N67_09515	COG0142	geranyltranstransferase activity
C6N67_09520	COG0051	transcription antitermination factor activity, RNA binding
C6N67_09525	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C6N67_09535	COG0089	rRNA binding
C6N67_09540	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C6N67_09545	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C6N67_09550	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C6N67_09555	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C6N67_09560	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C6N67_09565	COG0255	Belongs to the universal ribosomal protein uL29 family
C6N67_09575	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C6N67_09580	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C6N67_09585	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C6N67_09590	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C6N67_09595	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C6N67_09600	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C6N67_09605	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C6N67_09610	COG1841	ribosomal large subunit assembly
C6N67_09615	COG0200	Binds to the 23S rRNA
C6N67_09630	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C6N67_09635	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C6N67_09645	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C6N67_09650	COG0202	RNA polymerase activity
C6N67_09655	COG0203	ribosomal protein L17
C6N67_09680	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C6N67_09695	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C6N67_09720	COG0583	DNA-binding transcription factor activity
C6N67_09725	COG0114	fumarate hydratase activity
C6N67_09730	COG1053	succinate dehydrogenase
C6N67_09735	COG0471	metal ion transport
C6N67_09740	COG0039	L-malate dehydrogenase activity
C6N67_09745	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C6N67_09750	COG0215	cysteine-tRNA ligase activity
C6N67_09760	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C6N67_09765	COG1464	Belongs to the NlpA lipoprotein family
C6N67_09770	COG1854	S-ribosylhomocysteine lyase activity
C6N67_09775	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C6N67_09780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6N67_09795	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C6N67_09800	COG0250	Participates in transcription elongation, termination and antitermination
C6N67_09805	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C6N67_09810	COG0081	regulation of translation
C6N67_09815	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C6N67_09820	COG0222	ribosome binding
C6N67_09830	COG1121	(ABC) transporter
C6N67_09835	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C6N67_09845	COG1252	NADH dehydrogenase
C6N67_09855	COG1122	ATPase activity
C6N67_09860	COG1122	ATPase activity
C6N67_09870	COG0101	tRNA pseudouridine synthase activity
C6N67_09875	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C6N67_09890	COG0028	Belongs to the TPP enzyme family
C6N67_09900	COG1573	uracil-dna glycosylase
C6N67_09925	COG0671	phosphoesterase, PA-phosphatase related
C6N67_09930	COG2226	methyltransferase
C6N67_09940	COG2814	Major facilitator Superfamily
C6N67_09945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C6N67_09955	COG1660	Displays ATPase and GTPase activities
C6N67_09960	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C6N67_09965	COG1481	regulation of sporulation
C6N67_09970	COG0740	serine-type endopeptidase activity
C6N67_09985	COG1263	PTS System
C6N67_09985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6N67_09995	COG1914	H( )-stimulated, divalent metal cation uptake system
C6N67_10015	COG0039	L-malate dehydrogenase activity
C6N67_10020	COG0028	Belongs to the TPP enzyme family
C6N67_10025	COG3527	Alpha-acetolactate decarboxylase
C6N67_10035	COG1388	LysM domain
C6N67_10035	COG3942	CHAP domain
C6N67_10040	COG0791	NLP P60 protein
C6N67_10050	COG0756	dUTP diphosphatase activity
C6N67_10060	COG4956	integral membrane protein (PIN domain superfamily)
C6N67_10070	COG0653	protein targeting
C6N67_10075	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C6N67_10095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6N67_10105	COG1733	regulation of RNA biosynthetic process
C6N67_10110	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C6N67_10115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6N67_10115	COG0072	phenylalanine-tRNA ligase activity
C6N67_10120	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C6N67_10125	COG0514	ATP-dependent DNA helicase (RecQ)
C6N67_10130	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C6N67_10140	COG0768	penicillin binding
C6N67_10145	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C6N67_10160	COG1940	carbohydrate kinase activity
C6N67_10170	COG3409	Peptidoglycan-binding domain 1 protein
C6N67_10170	COG5632	N-Acetylmuramoyl-L-alanine amidase
C6N67_10175	COG3942	CHAP domain
C6N67_10195	COG0584	glycerophosphoryl diester phosphodiesterase
C6N67_10200	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C6N67_10205	COG0789	Transcriptional regulator
C6N67_10210	COG0174	glutamine synthetase
C6N67_10240	COG2801	Transposase and inactivated derivatives
C6N67_10255	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C6N67_10260	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C6N67_10285	COG0778	Nitroreductase
C6N67_10290	COG1169	isochorismate synthase
C6N67_10295	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C6N67_10300	COG0596	Alpha beta hydrolase
C6N67_10305	COG4948	Mandelate Racemase Muconate Lactonizing
C6N67_10330	COG0737	Belongs to the 5'-nucleotidase family
C6N67_10335	COG4470	Protein conserved in bacteria
C6N67_10340	COG0647	UMP catabolic process
C6N67_10350	COG4166	transmembrane transport
C6N67_10355	COG0673	inositol 2-dehydrogenase activity
C6N67_10380	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C6N67_10385	COG0573	inorganic phosphate transmembrane transporter activity
C6N67_10390	COG0581	inorganic phosphate transmembrane transporter activity
C6N67_10395	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C6N67_10400	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C6N67_10405	COG0704	Plays a role in the regulation of phosphate uptake
C6N67_10410	COG2137	regulation of response to DNA damage stimulus
C6N67_10450	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C6N67_10460	COG5506	Protein of unknown function (DUF1694)
C6N67_10470	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C6N67_10575	COG1272	protein, Hemolysin III
C6N67_10610	COG0525	valine-tRNA ligase activity
C6N67_10620	COG0285	dihydrofolate synthase activity
C6N67_10640	COG0488	(ABC) transporter
C6N67_10645	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C6N67_10650	COG0459	protein refolding
C6N67_10655	COG0531	amino acid
C6N67_10665	COG1181	Belongs to the D-alanine--D-alanine ligase family
C6N67_10670	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C6N67_10675	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C6N67_10685	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C6N67_10690	COG1713	HD superfamily hydrolase involved in NAD metabolism
C6N67_10695	COG0799	negative regulation of ribosome biogenesis
C6N67_10700	COG2226	methyltransferase
C6N67_10705	COG1323	Belongs to the UPF0348 family
C6N67_10715	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C6N67_10720	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C6N67_10815	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C6N67_10825	COG0363	glucosamine-6-phosphate deaminase activity
C6N67_10830	COG0776	regulation of translation
C6N67_10845	COG1136	(ABC) transporter
C6N67_10860	COG4720	Psort location CytoplasmicMembrane, score
C6N67_10865	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C6N67_10870	COG1570	exodeoxyribonuclease VII activity
C6N67_10880	COG0142	geranyltranstransferase activity
C6N67_10885	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C6N67_10890	COG1438	arginine binding
C6N67_10895	COG0497	DNA recombination
C6N67_10905	COG0194	GDP metabolic process
C6N67_10915	COG0586	Pfam SNARE associated Golgi protein
C6N67_10920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C6N67_10925	COG1098	S1 RNA binding domain
C6N67_11035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C6N67_11045	COG1271	oxidase subunit
C6N67_11050	COG1294	oxidase, subunit
C6N67_11055	COG4988	ABC transporter
C6N67_11060	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C6N67_11065	COG1388	LysM domain
C6N67_11065	COG1705	Flagellar rod assembly protein muramidase FlgJ
C6N67_11070	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C6N67_11090	COG0494	nUDIX hydrolase
C6N67_11100	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C6N67_11105	COG0346	lactoylglutathione lyase activity
C6N67_11110	COG0400	carboxylic ester hydrolase activity
C6N67_11120	COG0741	lytic transglycosylase activity
C6N67_11140	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C6N67_11145	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6N67_11150	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6N67_11160	COG4120	Belongs to the binding-protein-dependent transport system permease family
C6N67_11170	COG0038	chloride channel
C6N67_11175	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C6N67_11180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C6N67_11185	COG1307	EDD domain protein, DegV family
C6N67_11190	COG2190	(PTS) system
C6N67_11190	COG1263	PTS System
C6N67_11190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6N67_11205	COG2003	Belongs to the UPF0758 family
C6N67_11210	COG1077	Cell shape determining protein MreB Mrl
C6N67_11215	COG1792	Involved in formation and maintenance of cell shape
C6N67_11220	COG3338	carbonate dehydratase activity
C6N67_11230	COG0765	amino acid transport
C6N67_11235	COG1126	abc transporter atp-binding protein
C6N67_11250	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C6N67_11255	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C6N67_11260	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C6N67_11275	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C6N67_11285	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C6N67_11290	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C6N67_11295	COG0138	bifunctional purine biosynthesis protein purh
C6N67_11300	COG0151	Belongs to the GarS family
C6N67_11305	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C6N67_11320	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6N67_11335	COG0833	amino acid
C6N67_11345	COG2264	protein methyltransferase activity
C6N67_11350	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C6N67_11365	COG2001	Belongs to the MraZ family
C6N67_11370	COG0275	rRNA processing
C6N67_11385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C6N67_11390	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C6N67_11395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C6N67_11400	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C6N67_11405	COG0849	cell division
C6N67_11415	COG1799	cell septum assembly
C6N67_11430	COG3599	regulation of cell shape
C6N67_11450	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C6N67_11455	COG0217	transcriptional regulatory protein
C6N67_11460	COG2252	PERMEase
C6N67_11505	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C6N67_11510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C6N67_11515	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C6N67_11520	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C6N67_11520	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C6N67_11525	COG0631	protein serine/threonine phosphatase activity
C6N67_11530	COG2815	serine threonine protein kinase
C6N67_11530	COG0515	serine threonine protein kinase
C6N67_11535	COG1162	GTPase activity
C6N67_11540	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C6N67_11550	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C6N67_11560	COG1461	Dihydroxyacetone kinase
C6N67_11580	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C6N67_11585	COG0416	fatty acid biosynthetic process
C6N67_11590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C6N67_11595	COG0571	ribonuclease III activity
C6N67_11600	COG1196	nuclear chromosome segregation
C6N67_11605	COG0552	protein localization to endoplasmic reticulum
C6N67_11615	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C6N67_11630	COG0228	four-way junction DNA binding
C6N67_11635	COG0582	viral genome integration into host DNA