locus-tag	class	description
AO080_00035	ENOG4105E0X	reductase
AO080_00045	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AO080_00050	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AO080_00055	ENOG4108R6K	riboflavin synthase, subunit alpha
AO080_00060	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AO080_00065	ENOG41080TC	multidrug resistance protein
AO080_00070	ENOG4105KPY	Small multidrug resistance protein
AO080_00075	ENOG4107104	thymidine kinase
AO080_00090	ENOG4108RCR	degv family
AO080_00100	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AO080_00105	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AO080_00125	ENOG4108J59	Extracellular solute-binding protein, family 5
AO080_00140	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
AO080_00165	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AO080_00180	ENOG4105C7N	Xanthine uracil vitamin C permease
AO080_00190	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AO080_00195	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
AO080_00210	ENOG4105F27	Major Facilitator
AO080_00215	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AO080_00225	ENOG4105FDP	GntR family transcriptional regulator
AO080_00230	ENOG4105CE4	GlcNAc 6-P deacetylase
AO080_00235	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AO080_00245	ENOG4108HCJ	Hydrolase
AO080_00250	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AO080_00255	ENOG4108HCJ	Hydrolase
AO080_00275	ENOG4105II7	pyrroline-5-carboxylate reductase
AO080_00290	ENOG4105DFF	Rod shape-determining protein mreb
AO080_00295	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
AO080_00305	ENOG4105UIB	(ABC) transporter
AO080_00310	ENOG4108JQ9	ABC transporter
AO080_00315	ENOG4105DIH	basic membrane
AO080_00320	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AO080_00330	ENOG41080HT	Transcriptional regulator, arsr family
AO080_00335	ENOG4106F5Q	Membrane
AO080_00345	ENOG4105F0I	Aminotransferase
AO080_00360	ENOG4108V06	Glutathione peroxidase
AO080_00365	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AO080_00380	ENOG4105CAY	ferredoxin--nadp reductase
AO080_00395	ENOG4105DIH	basic membrane
AO080_00400	ENOG4105DIH	basic membrane
AO080_00405	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AO080_00410	ENOG4105WD1	Membrane
AO080_00435	ENOG4107PP3	Acetylornithine deacetylase
AO080_00445	ENOG410605W	Major Facilitator
AO080_00450	ENOG4105CDU	Replicative dna helicase
AO080_00455	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AO080_00465	ENOG4108JQ7	(ABC) transporter
AO080_00475	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AO080_00480	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AO080_00485	ENOG4108J59	Extracellular solute-binding protein, family 5
AO080_00490	ENOG4105DRP	amino acid AbC transporter
AO080_00495	ENOG4105EAD	ABC transporter
AO080_00500	ENOG4105CT1	(ABC) transporter
AO080_00505	ENOG4105CDA	abc transporter atp-binding protein
AO080_00520	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AO080_00525	ENOG4105VKD	bioY protein
AO080_00530	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AO080_00555	ENOG4105CT4	transporter
AO080_00560	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AO080_00575	ENOG4105EEM	helicase
AO080_00595	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
AO080_00605	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
AO080_00625	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
AO080_00630	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AO080_00635	ENOG4105C1J	atp-dependent rna helicase
AO080_00640	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AO080_00645	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AO080_00655	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
AO080_00660	ENOG410667J	hydrolase
AO080_00665	ENOG4105DCI	Phosphohydrolase
AO080_00675	ENOG4105C0H	protease
AO080_00680	ENOG4105Q2H	domain protein
AO080_00700	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AO080_00735	ENOG4108UUM	single-stranded DNA-binding protein
AO080_00740	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AO080_00750	ENOG4105DU0	nucleoside hydrolase
AO080_00755	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AO080_00765	ENOG4105DFT	pur operon repressor
AO080_00770	ENOG4108Z4K	mutator MutT protein
AO080_00785	ENOG410605W	Major Facilitator
AO080_00795	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
AO080_00800	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AO080_00815	ENOG4107QSE	Dipeptidase
AO080_00820	ENOG4107R7I	amino acid
AO080_00825	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
AO080_00835	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AO080_00840	ENOG4105C28	cystathionine
AO080_00865	ENOG4105CG5	Glycosyl transferase (Group 1
AO080_00870	ENOG4105C8T	Leucyl-tRNA synthetase
AO080_00875	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AO080_00885	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AO080_00915	ENOG4105DQ6	Transposase
AO080_00945	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AO080_00955	ENOG4108KGH	TRANSCRIPTIONal
AO080_00965	ENOG4105BZU	Histidine kinase
AO080_00970	ENOG4108STX	response regulator
AO080_00975	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AO080_01010	ENOG4105CD8	aminopeptidase N
AO080_01020	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AO080_01035	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
AO080_01045	ENOG4105DQ6	Transposase
AO080_01060	ENOG4105DC8	reductase
AO080_01090	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AO080_01110	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
AO080_01200	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AO080_01205	ENOG4105CHR	reductase
AO080_01215	ENOG4105DAA	L-lactate
AO080_01220	ENOG4107RGM	aldo keto reductase
AO080_01225	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
AO080_01240	ENOG4105DC8	reductase
AO080_01245	ENOG4108ZGC	gaf domain protein
AO080_01260	ENOG4105BZ1	(ABC) transporter
AO080_01265	ENOG4105BZ1	(ABC) transporter
AO080_01270	ENOG4105HJK	ABC transporter
AO080_01275	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AO080_01280	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AO080_01285	ENOG4108JQ7	(ABC) transporter
AO080_01290	ENOG4105C3U	ABC transporter
AO080_01295	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
AO080_01300	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
AO080_01305	ENOG4107RBJ	symporter
AO080_01320	ENOG4105C5I	Dehydrogenase
AO080_01325	ENOG4105CHM	Aminotransferase
AO080_01335	ENOG4105CK1	PTS System
AO080_01340	ENOG4105CS2	ec 3.2.1.21
AO080_01345	ENOG4105CS2	ec 3.2.1.21
AO080_01350	ENOG4105VCP	PTS System
AO080_01355	ENOG4105VZJ	PTS System
AO080_01360	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AO080_01465	ENOG4106KNT	transcriptional regulator
AO080_01480	ENOG4107BMA	Transglycosylase associated protein
AO080_01545	ENOG4105CRK	lysyL-tRNA synthetase
AO080_01550	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AO080_01565	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AO080_01575	ENOG41082I2	s4 domain protein
AO080_01585	ENOG4108JA2	transcriptioN-repair coupling factor
AO080_01590	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AO080_01605	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AO080_01610	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AO080_01615	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AO080_01620	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AO080_01645	ENOG4105CK1	PTS System
AO080_01650	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AO080_01655	ENOG4105EY8	ABC transporter
AO080_01665	ENOG4105CMG	Carbohydrate kinase
AO080_01670	ENOG4105C93	Xylose Isomerase
AO080_01680	ENOG4105CT4	transporter
AO080_01685	ENOG4105DSG	hydrolase family 43
AO080_01695	ENOG4107QNK	)-transporter
AO080_01715	ENOG4108R3E	Dna-3-methyladenine glycosylase i
AO080_01720	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AO080_01740	ENOG41067S9	phage shock protein C, PspC
AO080_01750	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
AO080_01765	ENOG4105D5T	phosphonate abc transporter
AO080_01780	ENOG4105C5Y	PTS System
AO080_01785	ENOG4108KGH	TRANSCRIPTIONal
AO080_01790	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AO080_01795	ENOG4108UK2	deaminase
AO080_01800	ENOG4105W42	Veg protein
AO080_01805	ENOG4105C37	(CBS) domain
AO080_01810	ENOG4105C37	(CBS) domain
AO080_01820	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
AO080_01825	ENOG4105F8V	Hydrolase, tatD family
AO080_01830	ENOG4105EEQ	Na H antiporter
AO080_01835	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AO080_01880	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AO080_01900	ENOG4105DQ6	Transposase
AO080_01910	ENOG4105E0M	Sulfatase
AO080_01925	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AO080_01930	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AO080_01935	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AO080_01940	ENOG410848D	S4 domain protein YaaA
AO080_01945	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AO080_01950	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AO080_01955	ENOG4105VG0	50S ribosomal protein l34
AO080_01960	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AO080_01965	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AO080_01970	ENOG4105C3F	Signal peptidase i
AO080_01975	ENOG4105E0A	ABC, transporter
AO080_01985	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
AO080_02000	ENOG4107ZYR	domain protein
AO080_02005	ENOG4105C85	amino acid
AO080_02025	ENOG4107QN2	dihydrolipoyl dehydrogenase
AO080_02035	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AO080_02060	ENOG4105C19	ABC transporter
AO080_02065	ENOG4107RBB	ABC transporter, permease
AO080_02070	ENOG4105EYF	MMPL domain protein
AO080_02075	ENOG4105DQF	Hydrolase
AO080_02085	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AO080_02105	ENOG4105KAF	membrAne
AO080_02110	ENOG4105C7N	Xanthine uracil vitamin C permease
AO080_02120	ENOG4105CP7	Triose-phosphate isomerase
AO080_02150	ENOG4105KIS	phospholipid-binding protein
AO080_02190	ENOG4105C2X	Arabinose 5-phosphate isomerase
AO080_02195	ENOG4105CS2	ec 3.2.1.21
AO080_02235	ENOG4107VQW	regulatoR
AO080_02240	ENOG4108HCJ	Hydrolase
AO080_02245	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AO080_02250	ENOG4105DIH	basic membrane
AO080_02255	ENOG4105CDH	Citrulline--aspartate ligase
AO080_02260	ENOG4105CH7	arginosuccinase
AO080_02265	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AO080_02270	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AO080_02275	ENOG4105CAS	nag kinase
AO080_02280	ENOG4105C8Y	Acetylornithine aminotransferase
AO080_02285	ENOG4105DBV	ornithine carbamoyltransferase
AO080_02290	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AO080_02295	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AO080_02315	ENOG4105CIG	ABC transporter
AO080_02335	ENOG4105VUF	Transcriptional regulator
AO080_02340	ENOG4105CHR	reductase
AO080_02350	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AO080_02360	ENOG4108UZ3	Transporter
AO080_02365	ENOG4105DIH	basic membrane
AO080_02385	ENOG41067TZ	transcriptional regulator, MarR family
AO080_02390	ENOG4105BZ1	(ABC) transporter
AO080_02410	ENOG41083J0	(ABC) transporter
AO080_02415	ENOG4105C4B	ABC transporter, permease
AO080_02425	ENOG4105CZV	ABC transporter
AO080_02435	ENOG4105CDA	abc transporter atp-binding protein
AO080_02440	ENOG4105E5Q	amino acid AbC transporter
AO080_02450	ENOG4105EAB	amino acid AbC transporter
AO080_02455	ENOG410855V	Acylphosphatase
AO080_02475	ENOG4105C02	permease
AO080_02480	ENOG4105KVH	Transcriptional regulator
AO080_02505	ENOG4105C85	amino acid
AO080_02535	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
AO080_02545	ENOG4105HMI	Membrane
AO080_02555	ENOG4105HMI	Membrane
AO080_02560	ENOG4108KB2	LysR family Transcriptional regulator
AO080_02565	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
AO080_02570	ENOG4105EA8	2-Nitropropane dioxygenase
AO080_02585	ENOG4105CI2	imidazolone-5-propionate hydrolase
AO080_02590	ENOG4105CUB	amino acid
AO080_02600	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
AO080_02610	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AO080_02620	ENOG4107U9W	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX (By similarity)
AO080_02630	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AO080_02635	ENOG4108J59	Extracellular solute-binding protein, family 5
AO080_02640	ENOG4107T66	Releases the N-terminal proline from various substrates (By similarity)
AO080_02645	ENOG4108M15	ABC transporter
AO080_02670	ENOG4108W5N	phosphatidylglycerophosphatase a
AO080_02675	ENOG4105CPQ	Dehydrogenase
AO080_02695	ENOG4107R7I	amino acid
AO080_02705	ENOG4105CUB	amino acid
AO080_02710	ENOG4105HDK	L-asparaginase
AO080_02715	ENOG4105VEM	Conserved domain protein
AO080_02725	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AO080_02735	ENOG4105KA0	thioesterase Superfamily protein
AO080_02740	ENOG4108IPT	Naphthoate synthase
AO080_02745	ENOG4105CEY	Amp-dependent synthetase and ligase
AO080_02760	ENOG4108STX	response regulator
AO080_02765	ENOG4105US7	Histidine kinase
AO080_02775	ENOG4105E66	phosphoriboisomerase A
AO080_02780	ENOG4105CEN	a g-specific adenine glycosylase
AO080_02795	ENOG4107QJE	Chromosome Partitioning Protein
AO080_02800	ENOG4105FA0	parb-like partition protein
AO080_02805	ENOG4105VDK	protein, conserved in bacteria
AO080_02810	ENOG4105C3G	gtp-binding protein
AO080_02820	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AO080_02880	ENOG4105DUX	Transporter
AO080_02890	ENOG4105CSC	Glucose uptake protein
AO080_02895	ENOG4105EVU	fructokinase
AO080_02900	ENOG4107QNK	)-transporter
AO080_02935	ENOG410906U	SprT-like
AO080_02940	ENOG4105EXC	Acyl-transferase
AO080_02945	ENOG41067TZ	transcriptional regulator, MarR family
AO080_02955	ENOG4105FDK	ABC transporter
AO080_02960	ENOG4105FAV	ABC, transporter
AO080_02965	ENOG4105E4P	ATPase (AAA
AO080_02970	ENOG4105C5H	ABC transporter
AO080_02975	ENOG4107R73	Mate efflux family protein
AO080_02990	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
AO080_03010	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
AO080_03035	ENOG4107QNK	)-transporter
AO080_03045	ENOG4105EAD	ABC transporter
AO080_03075	ENOG4107R8N	Glycosyl transferase, family 2
AO080_03085	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
AO080_03115	ENOG4105D3Q	Sugar transferase
AO080_03120	ENOG4108RYC	glycosyltransferase
AO080_03125	ENOG4108TZY	GntR Family Transcriptional Regulator
AO080_03130	ENOG4107QRI	Phosphoketolase
AO080_03150	ENOG4108RJ9	Glycosyl transferase, family 2
AO080_03155	ENOG4105DQ6	Transposase
AO080_03165	ENOG4108KMV	Glycosyl transferase (Group 1
AO080_03230	ENOG4105C9K	Endothelin-converting enzyme 1
AO080_03240	ENOG4108EKI	Dehydrogenase
AO080_03255	ENOG4105E4P	ATPase (AAA
AO080_03260	ENOG4105CGK	Exodeoxyribonuclease III
AO080_03280	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AO080_03285	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AO080_03300	ENOG4105BZ1	(ABC) transporter
AO080_03305	ENOG4105BZ1	(ABC) transporter
AO080_03310	ENOG4105E4P	ATPase (AAA
AO080_03335	ENOG4108UW5	maltose o-acetyltransferase
AO080_03345	ENOG4105DG6	mannose-6-phosphate isomerase
AO080_03350	ENOG4105DMS	mur ligase
AO080_03355	ENOG4105F1K	Glutamine amidotransferase
AO080_03365	ENOG4107104	thymidine kinase
AO080_03370	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AO080_03375	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AO080_03380	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AO080_03385	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AO080_03390	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AO080_03395	ENOG4105CGD	Nad-dependent epimerase dehydratase
AO080_03410	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
AO080_03415	ENOG4105WS6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AO080_03420	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
AO080_03425	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AO080_03430	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AO080_03435	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AO080_03440	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AO080_03445	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AO080_03450	ENOG4108VXD	carboxy-peptidase
AO080_03455	ENOG4105ZMH	deoxynucleoside kinase
AO080_03460	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AO080_03485	ENOG4105KEX	transcriptional regulator, ctsr
AO080_03495	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AO080_03500	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AO080_03515	ENOG4107QW4	alcohol dehydrogenase
AO080_03535	ENOG4107Z3H	Transcriptional regulator, TetR family
AO080_03540	ENOG4105DHI	Methyltransferase
AO080_03570	ENOG4108Z4K	mutator MutT protein
AO080_03585	ENOG41067QW	Transcriptional regulator
AO080_03595	ENOG4105DJ2	Major Facilitator Superfamily
AO080_03600	ENOG4108URH	decarboxylase
AO080_03605	ENOG4107Y49	methyltransferase
AO080_03615	ENOG4105C6E	dna polymerase iii
AO080_03625	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AO080_03640	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AO080_03645	ENOG4105X0R	protein from nitrogen regulatory protein P-II
AO080_03665	ENOG4105CMR	udp-glucose 4-epimerase
AO080_03670	ENOG41072GX	Peptidase M22 Glycoprotease
AO080_03695	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AO080_03700	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AO080_03705	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AO080_03710	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AO080_03715	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AO080_03725	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AO080_03730	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AO080_03740	ENOG41082SA	50s ribosomal protein l29
AO080_03745	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AO080_03750	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AO080_03755	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AO080_03760	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AO080_03765	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AO080_03770	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AO080_03780	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AO080_03790	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AO080_03795	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AO080_03805	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AO080_03810	ENOG41067V7	50S ribosomal protein L36
AO080_03815	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AO080_03820	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AO080_03825	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AO080_03830	ENOG4108ZT0	50S ribosomal protein l17
AO080_03850	ENOG4108UMI	ABC transporter, permease
AO080_03855	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AO080_03860	ENOG4105D01	(LipO)protein
AO080_03870	ENOG4105DAP	Nicotinate phosphoribosyltransferase
AO080_03875	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
AO080_03895	ENOG4107RSM	transcriptional regulator
AO080_03900	ENOG4105C9Q	fumarate hydratase class II
AO080_03905	ENOG4107EFR	Flavocytochrome c
AO080_03910	ENOG4107QPK	)-transporter
AO080_03915	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AO080_03920	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
AO080_03925	ENOG4105C8N	cysteinyl-tRNA synthetase
AO080_03930	ENOG4105C28	cystathionine
AO080_03940	ENOG4105D01	(LipO)protein
AO080_03945	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
AO080_03950	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AO080_03955	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AO080_03965	ENOG410683Z	Preprotein translocase SecE subunit
AO080_03970	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AO080_03975	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AO080_03980	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AO080_03985	ENOG4108VZM	50s ribosomal protein L10
AO080_03990	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AO080_04000	ENOG4105DIK	(ABC) transporter
AO080_04005	ENOG4105CC5	ABC transporter
AO080_04010	ENOG4105DSE	periplasmic solute binding protein
AO080_04025	ENOG4108JJB	ABC transporter
AO080_04030	ENOG4108JJB	ABC transporter
AO080_04040	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AO080_04045	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AO080_04050	ENOG4108UJD	30S ribosomal protein S9
AO080_04060	ENOG4105EMU	Dehydrogenase
AO080_04085	ENOG4105C7K	acetolactate synthase
AO080_04095	ENOG4108RG0	uracil-dna glycosylase
AO080_04120	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AO080_04130	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AO080_04135	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AO080_04145	ENOG4105CHW	UPF0052 protein
AO080_04150	ENOG4105CIE	May be required for sporulation (By similarity)
AO080_04155	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AO080_04170	ENOG4105C5Y	PTS System
AO080_04175	ENOG41086FC	50S ribosomal protein l32
AO080_04180	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
AO080_04200	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AO080_04260	ENOG4107YJ4	chain length determinant protein
AO080_04265	ENOG4105D3Q	Sugar transferase
AO080_04270	ENOG4108RYC	glycosyltransferase
AO080_04290	ENOG4105K64	Glycosyl transferase, family 2
AO080_04295	ENOG4108KMV	Glycosyl transferase (Group 1
AO080_04300	ENOG4105CJR	Integral membrane protein (MviN
AO080_04310	ENOG4108KGH	TRANSCRIPTIONal
AO080_04315	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
AO080_04345	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AO080_04355	ENOG4107FQX	Alpha-acetolactate decarboxylase
AO080_04365	ENOG41068JE	domain protein
AO080_04370	ENOG4105K4H	Nlp p60 protein
AO080_04380	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AO080_04390	ENOG4105CTP	PilT protein domain protein
AO080_04395	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AO080_04400	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AO080_04405	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AO080_04425	ENOG4108RWN	rrna methyltransferase
AO080_04440	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AO080_04445	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AO080_04455	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AO080_04460	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AO080_04470	ENOG4107RF6	penicillin-binding protein
AO080_04475	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AO080_04505	ENOG41068JE	domain protein
AO080_04525	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
AO080_04530	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AO080_04535	ENOG4105KV4	Transcriptional regulator
AO080_04540	ENOG4105C5F	glutamine synthetase
AO080_04570	ENOG4105K46	50S ribosomal protein l27
AO080_04590	ENOG4105BZ1	(ABC) transporter
AO080_04595	ENOG4108DBC	nitroreductase
AO080_04600	ENOG4105E4F	Isochorismate synthase
AO080_04605	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
AO080_04610	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
AO080_04615	ENOG4105DTQ	mandelate racemase muconate lactonizing
AO080_04620	ENOG4105DC7	peptidase M24
AO080_04635	ENOG4107R8B	5'-nucleotidase
AO080_04640	ENOG4105MMD	transcriptional regulator
AO080_04645	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
AO080_04650	ENOG4108J59	Extracellular solute-binding protein, family 5
AO080_04655	ENOG4105D9R	oxidoreductase
AO080_04680	ENOG4105CVA	phosphate
AO080_04685	ENOG4105C8U	phosphate abc transporter
AO080_04690	ENOG4105E2Z	phosphate ABC transporter (Permease
AO080_04695	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AO080_04700	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AO080_04705	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AO080_04710	ENOG410902V	Modulates RecA activity (By similarity)
AO080_04745	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AO080_04765	ENOG4105D1H	recombination factor protein RarA
AO080_04885	ENOG4108UT2	hemolysin iii
AO080_04915	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AO080_04925	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AO080_04930	ENOG4107XU6	Glycosyl transferase (Group 1
AO080_04945	ENOG4105C5H	ABC transporter
AO080_04950	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AO080_04955	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AO080_04960	ENOG4105C0X	amino acid
AO080_04975	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
AO080_04980	ENOG4105CQW	ribosome biogenesis GTPase YqeH
AO080_04990	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AO080_04995	ENOG4108WF2	Metal Dependent Phosphohydrolase
AO080_05005	ENOG4105DXX	methyltransferase
AO080_05010	ENOG4105CDE	UPF0348 protein
AO080_05020	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AO080_05025	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AO080_05125	ENOG4105C22	threonyL-tRNA synthetase
AO080_05130	ENOG4108Z6X	(sortase) family
AO080_05135	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
AO080_05140	ENOG4105K70	DNA-binding protein
AO080_05150	ENOG4107WD8	ABC transporter, permease
AO080_05170	ENOG4108V7D	UPF0397 protein
AO080_05175	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AO080_05180	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AO080_05185	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AO080_05190	ENOG4105CTB	Polyprenyl synthetase
AO080_05195	ENOG4105DX0	Hemolysin A
AO080_05200	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
AO080_05205	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AO080_05215	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AO080_05220	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AO080_05225	ENOG4105DQR	SNARE associated Golgi
AO080_05230	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AO080_05355	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AO080_05360	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AO080_05365	ENOG4108JJ9	ABC, transporter
AO080_05370	ENOG4108JJ8	(ABC) transporter
AO080_05380	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
AO080_05395	ENOG4108YZ4	nudix hydrolase
AO080_05405	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
AO080_05415	ENOG4105FBA	Phospholipase Carboxylesterase
AO080_05445	ENOG41067VN	Glutaredoxin
AO080_05450	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AO080_05455	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AO080_05465	ENOG4105C7J	ABC transporter, permease
AO080_05470	ENOG4108JJB	ABC transporter
AO080_05475	ENOG4105CMQ	Chloride channel
AO080_05480	ENOG41087RV	Protein CrcB homolog
AO080_05485	ENOG4106A8V	Protein CrcB homolog
AO080_05490	ENOG4105EPR	degv family
AO080_05495	ENOG4105CI1	PTS System
AO080_05515	ENOG4105W5Q	DNA repair protein (RadC
AO080_05520	ENOG4105DFF	Rod shape-determining protein mreb
AO080_05525	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AO080_05530	ENOG4108UHE	carbonic anhydrase
AO080_05540	ENOG4105E5Q	amino acid AbC transporter
AO080_05545	ENOG4105CDA	abc transporter atp-binding protein
AO080_05550	ENOG4105EAB	amino acid AbC transporter
AO080_05555	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AO080_05560	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AO080_05565	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AO080_05570	ENOG4105C8V	SAICAR synthetase
AO080_05575	ENOG410839H	phosphoribosylformylglycinamidine synthase
AO080_05580	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
AO080_05585	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
AO080_05595	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AO080_05600	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AO080_05605	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AO080_05610	ENOG4105C12	Phosphoribosylglycinamide synthetase
AO080_05615	ENOG4105CKU	formyltetrahydrofolate synthetase
AO080_05630	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AO080_05650	ENOG4108IQI	permease
AO080_05655	ENOG4105CA9	Pyruvate kinase
AO080_05660	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AO080_05665	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AO080_05675	ENOG4108V6E	Cell division protein mraZ
AO080_05680	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AO080_05690	ENOG4105CJN	penicillin-binding protein
AO080_05695	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AO080_05700	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AO080_05705	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AO080_05710	ENOG41087KY	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
AO080_05715	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AO080_05725	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
AO080_05760	ENOG4105C7H	Helicase, RecD TraA family
AO080_05765	ENOG4105CDY	transcriptional regulatory protein
AO080_05770	ENOG4105C7N	Xanthine uracil vitamin C permease
AO080_05815	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AO080_05820	ENOG4105C25	Primosomal protein n'
AO080_05825	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AO080_05830	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AO080_05835	ENOG4108ZF3	Phosphatase
AO080_05840	ENOG4105D9P	serine threonine protein kinase
AO080_05845	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AO080_05850	ENOG4105DJV	ribulose-phosphate 3-epimerase
AO080_05860	ENOG4105VB9	50S ribosomal protein l28
AO080_05870	ENOG4105DP4	dak2 domain fusion protein ylov
AO080_05885	ENOG4105E2K	Glycosyl transferase (Group 1
AO080_05895	ENOG4105CB5	ATP-dependent DNA helicase recG
AO080_05900	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AO080_05905	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AO080_05910	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AO080_05915	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AO080_05920	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AO080_05930	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AO080_05945	ENOG4105K5M	30s ribosomal protein S16
AO080_05950	ENOG4105VTR	Integrase
AO080_06195	ENOG4105DU1	integral membrane protein, terc
AO080_06210	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AO080_06215	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AO080_06220	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AO080_06230	ENOG4107AYK	membrAne
AO080_06235	ENOG41069HH	4-oxalocrotonate tautomerase
AO080_06250	ENOG4105ZMH	deoxynucleoside kinase
AO080_06255	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AO080_06260	ENOG410667J	hydrolase
AO080_06325	ENOG4105CDW	Resistance protein
AO080_06330	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
AO080_06335	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
AO080_06340	ENOG4105CS2	ec 3.2.1.21
AO080_06345	ENOG4105VZJ	PTS System
AO080_06350	ENOG4105VCP	PTS System
AO080_06355	ENOG4105CS2	ec 3.2.1.21
AO080_06360	ENOG4105CK1	PTS System
AO080_06370	ENOG4105DPN	Oligoendopeptidase f
AO080_06375	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AO080_06390	ENOG4105ETE	Transcriptional regulator (LacI family
AO080_06395	ENOG4105DC7	peptidase M24
AO080_06475	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AO080_06480	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
AO080_06495	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AO080_06500	ENOG4105CUT	histidyl-tRNA synthetase
AO080_06505	ENOG4105C9M	aspartyl-trna synthetase
AO080_06520	ENOG4107AYK	membrAne
AO080_06525	ENOG4105VCC	30S ribosomal protein S21
AO080_06530	ENOG4105KTH	gatB Yqey
AO080_06535	ENOG4105C9A	Phoh family
AO080_06540	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AO080_06550	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AO080_06560	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
AO080_06565	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
AO080_06570	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AO080_06730	ENOG4105IG6	Phage terminase, large subunit
AO080_06755	ENOG4105K5M	30s ribosomal protein S16
AO080_06830	ENOG4105DU1	integral membrane protein, terc
AO080_06840	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
AO080_06850	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AO080_06855	ENOG4105CNU	cell division protein FtsK
AO080_06865	ENOG4108IUX	(ABC) transporter
AO080_06870	ENOG4105RHA	ABC transporter, permease
AO080_06880	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AO080_06885	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AO080_06890	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AO080_06905	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AO080_06910	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AO080_06915	ENOG4105CPN	adenine deaminase
AO080_06920	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AO080_06925	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AO080_06930	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AO080_06965	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AO080_06970	ENOG4105VIE	preprotein translocase, subunit YajC
AO080_06975	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AO080_06980	ENOG4105SFS	phosphoesterase RecJ domain protein
AO080_06985	ENOG4105C1J	atp-dependent rna helicase
AO080_06990	ENOG4105BZW	Glycerate kinase
AO080_06995	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AO080_07000	ENOG4105VBH	UPF0297 protein
AO080_07005	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AO080_07010	ENOG4105VPH	UPF0473 protein
AO080_07015	ENOG4105VPH	UPF0473 protein
AO080_07020	ENOG4105KQC	Competence protein
AO080_07035	ENOG4105TQK	DNA polymerase iii, delta' subunit
AO080_07040	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AO080_07045	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AO080_07060	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AO080_07080	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AO080_07100	ENOG4105C98	muts2 protein
AO080_07120	ENOG4105K63	Thioredoxin
AO080_07125	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AO080_07130	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AO080_07135	ENOG4107FQX	Alpha-acetolactate decarboxylase
AO080_07155	ENOG4107QUV	Domain protein
AO080_07175	ENOG4107DB1	DUF218 domain
AO080_07215	ENOG4105C7K	acetolactate synthase
AO080_07225	ENOG4105CQB	FAD linked oxidase domain protein
AO080_07230	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AO080_07235	ENOG4105C9X	ppx gppa phosphatase
AO080_07250	ENOG4105DQ6	Transposase
AO080_07260	ENOG4105CQB	FAD linked oxidase domain protein
AO080_07265	ENOG4105CHM	Aminotransferase
AO080_07275	ENOG4105D01	(LipO)protein
AO080_07280	ENOG4105D01	(LipO)protein
AO080_07290	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
AO080_07295	ENOG4105DWF	phosphomethylpyrimidine kinase
AO080_07300	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AO080_07335	ENOG4105EVU	fructokinase
AO080_07410	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AO080_07415	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AO080_07435	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AO080_07440	ENOG4105EMS	pseudouridine synthase
AO080_07445	ENOG4105CJW	magnesium transporter
AO080_07450	ENOG4105C2C	drug resistance transporter, Bcr CflA
AO080_07465	ENOG4105DQ6	Transposase
AO080_07505	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
AO080_07515	ENOG4108U05	Transcriptional regulator
AO080_07520	ENOG41090PH	Protease synthase and sporulation negative regulatory protein pai 1
AO080_07535	ENOG4105PGM	cation diffusion facilitator family transporter
AO080_07575	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
AO080_07595	ENOG4105DQ6	Transposase
AO080_07605	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AO080_07610	ENOG4105C5Y	PTS System
AO080_07635	ENOG4105EYF	MMPL domain protein
AO080_07650	ENOG4105SKE	transcriptional Regulator LysR family
AO080_07655	ENOG4105E2A	Dehydrogenase
AO080_07670	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AO080_07685	ENOG4105EMV	Major Facilitator
AO080_07690	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AO080_07725	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AO080_07730	ENOG4105CHV	Transcription elongation factor NusA
AO080_07735	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
AO080_07745	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AO080_07750	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AO080_07755	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AO080_07760	ENOG4105CEP	NADH dehydrogenase
AO080_07770	ENOG4105DTN	riboflavin biosynthesis protein ribF
AO080_07775	ENOG4105F23	Fibronectin-binding protein
AO080_07780	ENOG4106N3A	copper homeostasis protein cutc
AO080_07800	ENOG4105EPR	degv family
AO080_07805	ENOG4108RCR	degv family
AO080_07810	ENOG41090WU	lipolytic protein G-D-S-L family
AO080_07820	ENOG4105VSD	UPF0346 protein
AO080_07825	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
AO080_07830	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AO080_07835	ENOG4105C79	DNA protecting protein DprA
AO080_07840	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AO080_07845	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AO080_07855	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
AO080_07860	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
AO080_07875	ENOG4108IJ7	Glycine betaine
AO080_07885	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AO080_07890	ENOG4105D01	(LipO)protein
AO080_07895	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AO080_07940	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AO080_07945	ENOG4105WBI	UPF0223 protein
AO080_07950	ENOG4105ECY	inositol monophosphatase
AO080_07955	ENOG4105CI3	gtp-binding protein typa
AO080_07960	ENOG4105CNI	cell division protein FtsW
AO080_07965	ENOG4105WUC	UPF0298 protein
AO080_07970	ENOG4106H78	methyltransferase
AO080_07975	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AO080_07980	ENOG41063PX	domain protein
AO080_07985	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AO080_07995	ENOG4108VA3	3-hexulose-6-phosphate synthase
AO080_08000	ENOG41080HJ	6-phospho 3-hexuloisomerase
AO080_08005	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AO080_08010	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AO080_08040	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AO080_08045	ENOG4105BZU	Histidine kinase
AO080_08050	ENOG4105DBI	uridine monophosphokinase
AO080_08055	ENOG4105CN9	Peptidase m42 family protein
AO080_08060	ENOG4108VDD	TRNA binding domain protein
AO080_08070	ENOG4105DFU	Cell wall formation (By similarity)
AO080_08075	ENOG4105HFZ	Membrane
AO080_08080	ENOG4105C2M	dna polymerase I
AO080_08085	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AO080_08090	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AO080_08115	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AO080_08120	ENOG4105GR3	Histidine kinase
AO080_08130	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
AO080_08140	ENOG4107SC7	Inner membrane transporter yjeM
AO080_08155	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
AO080_08165	ENOG4108JYZ	YitT family
AO080_08175	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
AO080_08195	ENOG4105DVT	helicase
AO080_08205	ENOG4105C5S	asparaginyl-tRNA synthetase
AO080_08220	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
AO080_08225	ENOG4108UKS	UPF0398 protein
AO080_08230	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
AO080_08240	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AO080_08245	ENOG4105C4R	Atp-dependent dna helicase
AO080_08250	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AO080_08270	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AO080_08280	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AO080_08285	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AO080_08290	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AO080_08295	ENOG4105DUX	Transporter
AO080_08300	ENOG4107VKM	6-phosphogluconolactonase
AO080_08310	ENOG4105K59	histidine triad (HIT) protein
AO080_08325	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AO080_08335	ENOG41065RQ	ADP-ribosylation crystallin J1
AO080_08360	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AO080_08365	ENOG4105GP2	5'(3')-deoxyribonucleotidase
AO080_08370	ENOG4105E98	transcriptional regulator DeoR family
AO080_08375	ENOG4105DE4	1-phosphofructokinase
AO080_08380	ENOG4105DM4	PTS System
AO080_08395	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
AO080_08410	ENOG4105CJ3	phosphate transporter
AO080_08425	ENOG4105CS2	ec 3.2.1.21
AO080_08445	ENOG4107R7I	amino acid
AO080_08455	ENOG4106KNP	GTP-binding protein LepA C-terminus
AO080_08470	ENOG4105IKJ	beta-galactosidase small subunit
AO080_08490	ENOG410807C	QueT transporter
AO080_08500	ENOG4107QTZ	amino acid
AO080_08510	ENOG4105EMU	Dehydrogenase
AO080_08520	ENOG4105C6K	Malic enzyme
AO080_08530	ENOG4105DC8	reductase
AO080_08545	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AO080_08550	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
AO080_08570	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AO080_08595	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AO080_08605	ENOG4105EGD	dinuclear metal center protein, YbgI family
AO080_08615	ENOG4106943	Heat shock protein
AO080_08620	ENOG41068YB	TPR repeat-containing protein
AO080_08655	ENOG4105EYH	Exonuclease
AO080_08660	ENOG4107RFY	SbcCD D subunit
AO080_08670	ENOG4105DJ2	Major Facilitator Superfamily
AO080_08675	ENOG4105PUK	Membrane
AO080_08680	ENOG4105DWF	phosphomethylpyrimidine kinase
AO080_08690	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AO080_08695	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AO080_08700	ENOG4105CAT	Cytidine monophosphate kinase
AO080_08710	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AO080_08720	ENOG4108SAX	Membrane
AO080_08735	ENOG4105FE9	pseudouridine synthase
AO080_08740	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AO080_08745	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AO080_08760	ENOG4105QNR	S1 RNA binding domain protein
AO080_08770	ENOG4107RWR	Sodium hydrogen exchanger
AO080_08780	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AO080_08785	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AO080_08790	ENOG4105C0B	DNA polymerase III (alpha subunit)
AO080_08800	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
AO080_08805	ENOG4105C5H	ABC transporter
AO080_08810	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AO080_08840	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AO080_08845	ENOG4105BZU	Histidine kinase
AO080_08860	ENOG4108KGH	TRANSCRIPTIONal
AO080_08865	ENOG4105K64	Glycosyl transferase, family 2
AO080_08880	ENOG4107QRS	glycosyltransferase group 2 family protein
AO080_08890	ENOG4108PQP	glycosyl transferase group 1
AO080_08895	ENOG4105D3Q	Sugar transferase
AO080_08900	ENOG4107YJ4	chain length determinant protein
AO080_08915	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AO080_08920	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AO080_08925	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AO080_08930	ENOG4105CE9	30S ribosomal protein S2
AO080_08935	ENOG4105VC4	domain protein
AO080_08940	ENOG41060K3	Methyltransferase
AO080_08945	ENOG4105F6E	Acyl-transferase
AO080_08950	ENOG4105Z8B	NlpC/P60 family
AO080_08965	ENOG4105VXM	UPF0154 protein
AO080_08970	ENOG4105VPS	UPF0291 protein
AO080_08975	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AO080_08990	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AO080_08995	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AO080_09015	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AO080_09020	ENOG4105CFG	Acts as a chaperone (By similarity)
AO080_09025	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AO080_09030	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AO080_09060	ENOG4108RJ9	Glycosyl transferase, family 2
AO080_09070	ENOG4105CKK	Glycosyl transferase, family 2
AO080_09080	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
AO080_09095	ENOG4105D5D	udp-galactopyranose mutase
AO080_09120	ENOG4105D3Q	Sugar transferase
AO080_09125	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AO080_09150	ENOG4107X35	defense response to bacterium
AO080_09170	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
AO080_09185	ENOG4105EY8	ABC transporter
AO080_09190	ENOG4105EJJ	Dehydrogenase
AO080_09195	ENOG4108QHG	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
AO080_09200	ENOG4105KPE	licD family
AO080_09225	ENOG4105WH5	Teichoic acid glycosylation protein
AO080_09230	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AO080_09240	ENOG4105DQ6	Transposase
AO080_09265	ENOG4107PBV	potassium channel
AO080_09380	ENOG4105K64	Glycosyl transferase, family 2
AO080_09395	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
AO080_09445	ENOG4105C88	aminopeptidase
AO080_09460	ENOG4108YBP	pseudouridine synthase
AO080_09485	ENOG4105CS9	pantothenic acid kinase
AO080_09490	ENOG4105EEM	helicase
AO080_09500	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AO080_09505	ENOG4105CEV	competence damage-inducible protein
AO080_09510	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AO080_09550	ENOG4105CMG	Carbohydrate kinase
AO080_09560	ENOG4106D4I	domain protein
AO080_09570	ENOG4105WZB	UPF0342 protein
AO080_09575	ENOG4105BZ4	penicillin-binding protein
AO080_09580	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
AO080_09605	ENOG4105C75	arginyL-tRNA synthetase
AO080_09615	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AO080_09620	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AO080_09630	ENOG4105DIK	(ABC) transporter
AO080_09635	ENOG4105CC5	ABC transporter
AO080_09640	ENOG4108XAN	ABC transporter
AO080_09650	ENOG4105CBD	Diacylglycerol kinase
AO080_09655	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AO080_09660	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AO080_09665	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AO080_09670	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AO080_09675	ENOG4108KP7	hydrolase
AO080_09680	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
AO080_09695	ENOG4105K7K	Transcriptional regulator
AO080_09705	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
AO080_09725	ENOG4105CPC	Aldo Keto reductase
AO080_09730	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AO080_09735	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
AO080_09740	ENOG4108JJB	ABC transporter
AO080_09755	ENOG4105FF2	Type I DHQase
AO080_09760	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AO080_09765	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AO080_09770	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AO080_09775	ENOG4105D49	3-dehydroquinate synthase
AO080_09780	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
AO080_09785	ENOG4105E2X	shikimate dehydrogenase
AO080_09805	ENOG4105CHM	Aminotransferase
AO080_09825	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AO080_09830	ENOG4105CHM	Aminotransferase
AO080_09835	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AO080_09840	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AO080_09845	ENOG4105CH2	amidohydrolase
AO080_09860	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AO080_09865	ENOG4105CFH	Aspartokinase
AO080_09875	ENOG4105ETE	Transcriptional regulator (LacI family
AO080_09880	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AO080_09895	ENOG41080S5	HTH_DTXR
AO080_09915	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
AO080_09925	ENOG4105FDU	atp-dependent rna helicase
AO080_09930	ENOG4105EE0	oxidoreductase
AO080_09935	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AO080_09950	ENOG4105DQ6	Transposase
AO080_09965	ENOG4108V0P	LemA family
AO080_09975	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
AO080_09995	ENOG4105E66	phosphoriboisomerase A
AO080_10005	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AO080_10010	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AO080_10015	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AO080_10025	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AO080_10030	ENOG4105CHR	reductase
AO080_10035	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AO080_10040	ENOG4105EA8	2-Nitropropane dioxygenase
AO080_10045	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AO080_10050	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AO080_10055	ENOG41067TZ	transcriptional regulator, MarR family
AO080_10060	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AO080_10070	ENOG4105C83	adenylosuccinate lyase
AO080_10075	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
AO080_10080	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AO080_10085	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AO080_10090	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
AO080_10095	ENOG4105C34	Pseudouridine synthase
AO080_10105	ENOG4105VND	Ribonuclease
AO080_10110	ENOG4105DFD	Na H antiporter
AO080_10115	ENOG4105CTD	carboxy-peptidase
AO080_10120	ENOG4105C85	amino acid
AO080_10140	ENOG4105CHR	reductase
AO080_10165	ENOG4105DQ6	Transposase
AO080_10170	ENOG4108IMY	Transcriptional regulator
AO080_10190	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AO080_10200	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AO080_10205	ENOG4105CV8	reductase
AO080_10215	ENOG4108EKI	Dehydrogenase
AO080_10220	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AO080_10230	ENOG4105C5Q	Transcriptional regulator
AO080_10235	ENOG4105BZA	Phosphoglycerate kinase
AO080_10240	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AO080_10275	ENOG4105ZT7	DNA-entry nuclease
AO080_10285	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AO080_10295	ENOG4105F3R	pts system mannose fructose sorbose family iid
AO080_10300	ENOG4105ETZ	PTS System
AO080_10315	ENOG41065RQ	ADP-ribosylation crystallin J1
AO080_10380	ENOG4105E0M	Sulfatase
AO080_10395	ENOG4105W2C	Glycosyl transferase
AO080_10400	ENOG4105BZF	Glycosyl transferase (Group 1
AO080_10405	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AO080_10410	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AO080_10415	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
AO080_10420	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AO080_10425	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AO080_10430	ENOG4105CD3	dihydroorotase
AO080_10435	ENOG4105CXT	aspartate transcarbamylase
AO080_10455	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AO080_10460	ENOG4107U5W	ybbr family
AO080_10470	ENOG4105EEQ	Na H antiporter
AO080_10475	ENOG4105D4A	Cell wall formation (By similarity)
AO080_10480	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AO080_10490	ENOG4105K8N	protein family UPF0079, ATPase
AO080_10495	ENOG4108IJ2	phosphate acetyltransferase
AO080_10500	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AO080_10510	ENOG410839T	multidrug resistance protein
AO080_10515	ENOG41080TC	multidrug resistance protein
AO080_10525	ENOG4105E5Q	amino acid AbC transporter
AO080_10530	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AO080_10540	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AO080_10545	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AO080_10555	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AO080_10560	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AO080_10565	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AO080_10580	ENOG4105DQ6	Transposase
AO080_10590	ENOG4105CP7	Triose-phosphate isomerase
AO080_10595	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AO080_10600	ENOG4105KRI	phosphocarrier protein (HPr
AO080_10610	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AO080_10615	ENOG4105C3M	thioredoxin reductase
AO080_10650	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
AO080_10655	ENOG41086DT	Membrane protein of unknown function
AO080_10665	ENOG4107YZX	Universal stress protein
AO080_10675	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AO080_10680	ENOG4108HM4	ABC transporter
AO080_10685	ENOG4105D38	putrescine abc transporter
AO080_10690	ENOG4105F38	ABC transporter, permease
AO080_10695	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AO080_10705	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AO080_10710	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AO080_10715	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AO080_10720	ENOG4108JQ7	(ABC) transporter
AO080_10725	ENOG4105C3U	ABC transporter
AO080_10730	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AO080_10745	ENOG4105D6E	homoserine dehydrogenase
AO080_10750	ENOG4105C28	cystathionine
AO080_10755	ENOG4105CVG	Homoserine O-transsuccinylase
AO080_10765	ENOG4105DIH	basic membrane
AO080_10770	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AO080_10775	ENOG4105VJV	50s ribosomal protein L35
AO080_10780	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AO080_10785	ENOG4105M7K	Involved in the transcription termination process (By similarity)
AO080_10790	ENOG4108ZSR	alkaline shock protein
AO080_10795	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AO080_10800	ENOG4107QYV	phosphohexose isomerase
AO080_10805	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
AO080_10815	ENOG4105CSC	Glucose uptake protein
AO080_10820	ENOG4105BZU	Histidine kinase
AO080_10825	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AO080_10835	ENOG4105DZC	cytosine deaminase
AO080_10840	ENOG4105D9R	oxidoreductase
AO080_10865	ENOG4105D64	Mechanosensitive ion channel
AO080_10875	ENOG4105CDA	abc transporter atp-binding protein
AO080_11005	ENOG4105CHR	reductase
AO080_11025	ENOG4105DQ6	Transposase
AO080_11035	ENOG4105E66	phosphoriboisomerase A
AO080_11045	ENOG4105EDR	glucose galactose transporter
AO080_11050	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
AO080_11055	ENOG4105ETE	Transcriptional regulator (LacI family
AO080_11075	ENOG4105D7K	pfkb domain protein
AO080_11090	ENOG4108M60	Transcriptional regulator
AO080_11125	ENOG4105FCD	Major Facilitator
AO080_11135	ENOG4105CEY	Amp-dependent synthetase and ligase
AO080_11150	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AO080_11160	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AO080_11165	ENOG4105EUJ	GTP cyclohydrolase i
AO080_11170	ENOG4105EUJ	GTP cyclohydrolase i
AO080_11185	ENOG4108HCJ	Hydrolase
AO080_11200	ENOG4105D01	(LipO)protein
AO080_11205	ENOG4105D7K	pfkb domain protein
AO080_11210	ENOG4108UHU	Aldolase
AO080_11215	ENOG4105D2H	Uronic isomerase
AO080_11225	ENOG4105DEI	Mannitol dehydrogenase
AO080_11240	ENOG4107URF	beta-phospho-glucomutase
AO080_11255	ENOG4105FKQ	transcriptional regulator
AO080_11290	ENOG4105C19	ABC transporter
AO080_11295	ENOG4105KA3	membrAne
AO080_11310	ENOG4105D5Q	Arginine ornithine antiporter
AO080_11315	ENOG4105DBV	ornithine carbamoyltransferase
AO080_11320	ENOG4105CEU	Arginine dihydrolase
AO080_11325	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
AO080_11330	ENOG4105C59	p-type ATPase
AO080_11480	ENOG4108XFH	Transcriptional regulator
AO080_11500	ENOG4105CID	antiterminator
AO080_11505	ENOG4105CS2	ec 3.2.1.21
AO080_11510	ENOG41066F8	ROK family
AO080_11545	ENOG4105MS2	ribosomal subunit Interface protein
AO080_11550	ENOG41081UC	Inherit from COG: Competence protein
AO080_11560	ENOG4105CVA	phosphate
AO080_11630	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AO080_11635	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AO080_11640	ENOG4105DZP	Membrane-associated zinc metalloprotease
AO080_11645	ENOG4105KNE	Phosphatidate cytidylyltransferase
AO080_11650	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AO080_11655	ENOG4108HCJ	Hydrolase
AO080_11660	ENOG4105WH5	Teichoic acid glycosylation protein
AO080_11685	ENOG4108UQV	Membrane
AO080_11690	ENOG4107QW4	alcohol dehydrogenase
AO080_11700	ENOG4105E90	ABC transporter
AO080_11710	ENOG4105E0X	reductase
AO080_11740	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AO080_11780	ENOG4107BMA	Transglycosylase associated protein
AO080_11810	ENOG4105HUF	DNA protection during starvation protein
AO080_11815	ENOG4105IJJ	transcriptional regulator, crp fnr family
AO080_11835	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AO080_11855	ENOG4105DQ6	Transposase
AO080_11875	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AO080_11895	ENOG4107QNK	)-transporter
AO080_11920	ENOG4105VBF	alkaline shock protein
AO080_11935	ENOG4107BMA	Transglycosylase associated protein
AO080_11965	ENOG4105HUF	DNA protection during starvation protein
AO080_12030	ENOG4105E2A	Dehydrogenase
AO080_12035	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AO080_12130	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AO080_12165	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AO080_12200	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AO080_12215	ENOG4105QVS	general stress protein
AO080_12235	ENOG4105QVS	general stress protein
AO080_12255	ENOG4105F38	ABC transporter, permease
AO080_12260	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
AO080_12265	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)