locus-tag	class	description
AO080_00035	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AO080_00045	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AO080_00050	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AO080_00050	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AO080_00055	COG0307	riboflavin synthase, alpha
AO080_00060	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AO080_00060	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AO080_00065	COG2076	Multidrug Resistance protein
AO080_00070	COG2076	Multidrug Resistance protein
AO080_00075	COG1435	thymidine kinase activity
AO080_00090	COG1307	EDD domain protein, DegV family
AO080_00095	COG0656	L-ascorbic acid biosynthetic process
AO080_00100	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AO080_00105	COG2814	Major facilitator Superfamily
AO080_00125	COG4166	transmembrane transport
AO080_00170	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AO080_00180	COG2252	PERMEase
AO080_00190	COG0352	thiamine-phosphate diphosphorylase activity
AO080_00195	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AO080_00210	COG2814	Major facilitator Superfamily
AO080_00215	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AO080_00235	COG0577	efflux transmembrane transporter activity
AO080_00235	COG1136	(ABC) transporter
AO080_00245	COG0561	phosphatase activity
AO080_00250	COG2169	Transcriptional regulator
AO080_00250	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AO080_00255	COG0561	phosphatase activity
AO080_00275	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AO080_00280	COG0772	Belongs to the SEDS family
AO080_00290	COG1077	Cell shape determining protein MreB Mrl
AO080_00295	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AO080_00320	COG0446	pyridine nucleotide-disulphide oxidoreductase
AO080_00330	COG0640	Transcriptional regulator
AO080_00335	COG0628	permease
AO080_00340	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AO080_00360	COG0386	Belongs to the glutathione peroxidase family
AO080_00365	COG0588	phosphoglycerate mutase activity
AO080_00380	COG0492	ferredoxin-NADP+ reductase activity
AO080_00395	COG1744	ABC transporter substrate-binding protein PnrA-like
AO080_00405	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AO080_00410	COG2832	Protein of unknown function (DUF454)
AO080_00435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AO080_00445	COG2814	Major facilitator Superfamily
AO080_00450	COG0305	Participates in initiation and elongation during chromosome replication
AO080_00455	COG0359	binds to the 23S rRNA
AO080_00465	COG4608	Belongs to the ABC transporter superfamily
AO080_00470	COG0444	Belongs to the ABC transporter superfamily
AO080_00475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AO080_00480	COG0601	transmembrane transport
AO080_00485	COG4166	transmembrane transport
AO080_00490	COG0765	amino acid transport
AO080_00495	COG0765	amino acid transport
AO080_00500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AO080_00505	COG1126	abc transporter atp-binding protein
AO080_00520	COG0194	GDP metabolic process
AO080_00525	COG1268	BioY protein
AO080_00530	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AO080_00530	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AO080_00555	COG2211	Major facilitator Superfamily
AO080_00560	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AO080_00575	COG3973	AAA domain
AO080_00595	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AO080_00605	COG1696	Membrane protein involved in D-alanine export
AO080_00625	COG2337	Toxic component of a toxin-antitoxin (TA) module
AO080_00640	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AO080_00645	COG0504	CTP synthase activity
AO080_00655	COG3343	RNA polymerase activity
AO080_00660	COG0561	phosphatase activity
AO080_00665	COG1078	dGTPase activity
AO080_00675	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AO080_00680	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AO080_00700	COG0745	RESPONSE REGULATOR receiver
AO080_00730	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AO080_00735	COG0629	single-stranded DNA binding
AO080_00740	COG0360	Binds together with S18 to 16S ribosomal RNA
AO080_00755	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AO080_00765	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AO080_00770	COG1051	belongs to the nudix hydrolase family
AO080_00785	COG2814	Major facilitator Superfamily
AO080_00790	COG1064	alcohol dehydrogenase
AO080_00795	COG1074	ATP-dependent DNA helicase activity
AO080_00800	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AO080_00815	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AO080_00820	COG0531	amino acid
AO080_00825	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AO080_00835	COG1902	pentaerythritol trinitrate reductase activity
AO080_00840	COG0626	cystathionine gamma-synthase activity
AO080_00855	COG2244	polysaccharide biosynthetic process
AO080_00865	COG0438	transferase activity, transferring glycosyl groups
AO080_00870	COG0495	leucyl-tRNA aminoacylation
AO080_00875	COG0671	phosphoesterase, PA-phosphatase related
AO080_00885	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AO080_00910	COG2723	6-phospho-beta-galactosidase activity
AO080_00915	COG2801	Transposase and inactivated derivatives
AO080_00930	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AO080_00945	COG0024	Methionine aminopeptidase
AO080_00955	COG1316	TRANSCRIPTIONal
AO080_00965	COG2205	protein histidine kinase activity
AO080_00970	COG0745	RESPONSE REGULATOR receiver
AO080_00975	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AO080_01010	COG0308	aminopeptidase N
AO080_01015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AO080_01020	COG0542	response to heat
AO080_01035	COG0395	ABC-type sugar transport system, permease component
AO080_01045	COG2801	Transposase and inactivated derivatives
AO080_01090	COG2814	Major facilitator Superfamily
AO080_01110	COG1914	H( )-stimulated, divalent metal cation uptake system
AO080_01175	COG0438	transferase activity, transferring glycosyl groups
AO080_01200	COG2084	Dehydrogenase
AO080_01205	COG1028	Short-chain dehydrogenase reductase Sdr
AO080_01215	COG1620	l-lactate permease
AO080_01220	COG4989	oxidoreductase activity
AO080_01225	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AO080_01230	COG2233	PERMEase
AO080_01245	COG1956	GAF domain-containing protein
AO080_01260	COG1132	(ABC) transporter
AO080_01265	COG1132	(ABC) transporter
AO080_01270	COG0747	negative chemotaxis
AO080_01275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AO080_01280	COG0601	transmembrane transport
AO080_01285	COG4608	Belongs to the ABC transporter superfamily
AO080_01290	COG0444	Belongs to the ABC transporter superfamily
AO080_01295	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AO080_01300	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AO080_01305	COG2190	(PTS) system
AO080_01305	COG2211	Major facilitator Superfamily
AO080_01320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AO080_01325	COG0436	Aminotransferase
AO080_01335	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AO080_01340	COG2723	6-phospho-beta-galactosidase activity
AO080_01345	COG2723	6-phospho-beta-galactosidase activity
AO080_01350	COG1447	Phosphotransferase system cellobiose-specific component IIA
AO080_01355	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AO080_01360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AO080_01375	COG1215	transferase activity, transferring glycosyl groups
AO080_01390	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AO080_01460	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AO080_01465	COG1737	Transcriptional regulator
AO080_01475	COG0656	L-ascorbic acid biosynthetic process
AO080_01480	COG2261	transglycosylase associated protein
AO080_01545	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AO080_01550	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AO080_01565	COG0037	tRNA processing
AO080_01575	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AO080_01580	COG2244	polysaccharide biosynthetic process
AO080_01585	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AO080_01590	COG0193	aminoacyl-tRNA hydrolase activity
AO080_01600	COG0058	SHG alpha-glucan phosphorylase activity
AO080_01605	COG0297	glycogen (starch) synthase activity
AO080_01610	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AO080_01620	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AO080_01630	COG1309	transcriptional regulator
AO080_01645	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AO080_01650	COG0477	Major facilitator Superfamily
AO080_01655	COG1134	teichoic acid transport
AO080_01655	COG1388	LysM domain
AO080_01670	COG2115	Belongs to the xylose isomerase family
AO080_01680	COG2211	Major facilitator Superfamily
AO080_01685	COG3507	Belongs to the glycosyl hydrolase 43 family
AO080_01715	COG2818	Glycosylase
AO080_01720	COG1968	undecaprenyl-diphosphatase activity
AO080_01735	COG1695	Transcriptional regulator
AO080_01740	COG1983	PspC domain protein
AO080_01745	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AO080_01750	COG0737	Belongs to the 5'-nucleotidase family
AO080_01765	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AO080_01780	COG1263	PTS System
AO080_01780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AO080_01785	COG1316	TRANSCRIPTIONal
AO080_01790	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AO080_01795	COG2131	deaminase
AO080_01800	COG4466	Protein conserved in bacteria
AO080_01805	COG1253	flavin adenine dinucleotide binding
AO080_01810	COG1253	flavin adenine dinucleotide binding
AO080_01815	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AO080_01820	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AO080_01825	COG0084	hydrolase, TatD family'
AO080_01835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AO080_01835	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AO080_01880	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AO080_01900	COG2801	Transposase and inactivated derivatives
AO080_01910	COG1368	sulfuric ester hydrolase activity
AO080_01915	COG2153	protein acetylation
AO080_01930	COG0187	DNA topoisomerase II activity
AO080_01935	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AO080_01940	COG2501	S4 domain
AO080_01945	COG0592	DNA-directed DNA polymerase activity
AO080_01950	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AO080_01955	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AO080_01960	COG0594	ribonuclease P activity
AO080_01965	COG0706	membrane insertase activity
AO080_01975	COG1120	ATPase activity
AO080_01985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AO080_02000	COG0569	domain protein
AO080_02005	COG1113	amino acid transport
AO080_02025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AO080_02035	COG0446	pyridine nucleotide-disulphide oxidoreductase
AO080_02045	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AO080_02050	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AO080_02060	COG1136	(ABC) transporter
AO080_02065	COG0577	efflux transmembrane transporter activity
AO080_02070	COG1033	growth of symbiont in host cell
AO080_02070	COG2409	Drug exporters of the RND superfamily
AO080_02075	COG0561	phosphatase activity
AO080_02085	COG0328	RNA-DNA hybrid ribonuclease activity
AO080_02105	COG3152	Membrane
AO080_02110	COG2252	PERMEase
AO080_02150	COG1881	PFAM PEBP family protein
AO080_02190	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AO080_02190	COG0517	IMP dehydrogenase activity
AO080_02195	COG2723	6-phospho-beta-galactosidase activity
AO080_02225	COG0697	spore germination
AO080_02240	COG0561	phosphatase activity
AO080_02250	COG1744	ABC transporter substrate-binding protein PnrA-like
AO080_02255	COG0137	argininosuccinate synthase activity
AO080_02260	COG0165	Argininosuccinate lyase
AO080_02265	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AO080_02270	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AO080_02275	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AO080_02280	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AO080_02285	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AO080_02290	COG0505	Belongs to the CarA family
AO080_02295	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AO080_02315	COG1131	(ABC) transporter
AO080_02335	COG0789	Transcriptional regulator
AO080_02340	COG1028	Short-chain dehydrogenase reductase Sdr
AO080_02350	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AO080_02360	COG0697	spore germination
AO080_02365	COG1744	ABC transporter substrate-binding protein PnrA-like
AO080_02385	COG1846	Transcriptional regulator
AO080_02390	COG1132	(ABC) transporter
AO080_02400	COG0656	L-ascorbic acid biosynthetic process
AO080_02410	COG4619	ABC transporter
AO080_02415	COG0390	transport system, permease component
AO080_02425	COG1131	(ABC) transporter
AO080_02435	COG1126	abc transporter atp-binding protein
AO080_02440	COG0765	amino acid transport
AO080_02445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AO080_02450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AO080_02455	COG1254	Belongs to the acylphosphatase family
AO080_02465	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AO080_02465	COG0392	lysyltransferase activity
AO080_02475	COG0628	permease
AO080_02505	COG1113	amino acid transport
AO080_02530	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AO080_02535	COG0454	-acetyltransferase
AO080_02535	COG0456	acetyltransferase
AO080_02545	COG2855	membrane
AO080_02555	COG2855	membrane
AO080_02560	COG0583	DNA-binding transcription factor activity
AO080_02570	COG2070	2-Nitropropane dioxygenase
AO080_02585	COG1228	amidohydrolase
AO080_02590	COG0531	amino acid
AO080_02600	COG3223	Belongs to the PsiE family
AO080_02610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AO080_02620	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AO080_02630	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AO080_02635	COG4166	transmembrane transport
AO080_02640	COG2267	carboxylic ester hydrolase activity
AO080_02645	COG1131	(ABC) transporter
AO080_02670	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AO080_02675	COG1063	alcohol dehydrogenase
AO080_02685	COG4975	Glucose uptake
AO080_02695	COG0531	amino acid
AO080_02700	COG1113	amino acid transport
AO080_02705	COG0531	amino acid
AO080_02710	COG0252	asparaginase activity
AO080_02715	COG4443	Transcriptional Coactivator p15 (PC4)
AO080_02725	COG2226	methyltransferase
AO080_02730	COG1335	isochorismatase
AO080_02735	COG2050	protein possibly involved in aromatic compounds catabolism
AO080_02740	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AO080_02745	COG0318	PFAM AMP-dependent synthetase and ligase
AO080_02760	COG0745	RESPONSE REGULATOR receiver
AO080_02765	COG5002	protein histidine kinase activity
AO080_02775	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AO080_02780	COG1194	a g-specific adenine glycosylase
AO080_02790	COG0357	Ribosomal RNA small subunit methyltransferase G
AO080_02795	COG1192	Involved in chromosome partitioning
AO080_02800	COG1475	DNA binding
AO080_02805	COG4481	Protein conserved in bacteria
AO080_02810	COG0012	GTP binding
AO080_02820	COG0745	RESPONSE REGULATOR receiver
AO080_02830	COG1686	Belongs to the peptidase S11 family
AO080_02880	COG3104	oligopeptide transport
AO080_02885	COG0477	Major facilitator Superfamily
AO080_02890	COG4975	Glucose uptake
AO080_02935	COG3091	SprT-like family
AO080_02940	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AO080_02940	COG2755	lipolytic protein G-D-S-L family
AO080_02945	COG1846	Transcriptional regulator
AO080_02955	COG1121	(ABC) transporter
AO080_02960	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AO080_02965	COG1373	ATPase (AAA superfamily
AO080_02970	COG0488	(ABC) transporter
AO080_02975	COG0534	Mate efflux family protein
AO080_02990	COG3940	Belongs to the glycosyl hydrolase 43 family
AO080_03010	COG2160	L-arabinose isomerase activity
AO080_03015	COG0656	L-ascorbic acid biosynthetic process
AO080_03045	COG0765	amino acid transport
AO080_03075	COG1215	transferase activity, transferring glycosyl groups
AO080_03085	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AO080_03100	COG1418	mRNA catabolic process
AO080_03105	COG2814	Major facilitator Superfamily
AO080_03125	COG2188	Transcriptional regulator
AO080_03130	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AO080_03150	COG1216	Glycosyl transferase, family 2
AO080_03155	COG2801	Transposase and inactivated derivatives
AO080_03165	COG0438	transferase activity, transferring glycosyl groups
AO080_03170	COG1442	glycosyl transferase family 8
AO080_03170	COG1216	Glycosyl transferase, family 2
AO080_03180	COG5039	Polysaccharide pyruvyl transferase
AO080_03230	COG3590	peptidase
AO080_03240	COG1012	belongs to the aldehyde dehydrogenase family
AO080_03240	COG1454	alcohol dehydrogenase
AO080_03255	COG1373	ATPase (AAA superfamily
AO080_03260	COG0708	Exodeoxyribonuclease III
AO080_03280	COG0588	phosphoglycerate mutase activity
AO080_03300	COG1132	(ABC) transporter
AO080_03305	COG1132	(ABC) transporter
AO080_03310	COG1373	ATPase (AAA superfamily
AO080_03335	COG0110	maltose O-acetyltransferase activity
AO080_03345	COG1482	cell wall glycoprotein biosynthetic process
AO080_03350	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AO080_03355	COG3442	glutamine amidotransferase
AO080_03365	COG1435	thymidine kinase activity
AO080_03370	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AO080_03375	COG2890	protein-(glutamine-N5) methyltransferase activity
AO080_03380	COG0009	L-threonylcarbamoyladenylate synthase
AO080_03385	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AO080_03390	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AO080_03395	COG0702	epimerase
AO080_03405	COG2233	PERMEase
AO080_03410	COG0356	it plays a direct role in the translocation of protons across the membrane
AO080_03415	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AO080_03420	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AO080_03425	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AO080_03430	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AO080_03435	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AO080_03440	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AO080_03445	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AO080_03450	COG1876	peptidase activity
AO080_03455	COG1428	Deoxynucleoside kinase
AO080_03460	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AO080_03485	COG4463	regulation of RNA biosynthetic process
AO080_03490	COG0542	response to heat
AO080_03495	COG0085	RNA polymerase activity
AO080_03515	COG1979	alcohol dehydrogenase
AO080_03535	COG1309	transcriptional regulator
AO080_03540	COG0500	methyltransferase
AO080_03570	COG1051	belongs to the nudix hydrolase family
AO080_03585	COG3620	sequence-specific DNA binding
AO080_03595	COG2807	transmembrane transport
AO080_03605	COG2813	Specifically methylates the guanine in position
AO080_03615	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AO080_03640	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AO080_03645	COG3870	Protein conserved in bacteria
AO080_03665	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AO080_03670	COG1214	PFAM Peptidase M22, glycoprotease
AO080_03685	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AO080_03690	COG0142	geranyltranstransferase activity
AO080_03695	COG0051	transcription antitermination factor activity, RNA binding
AO080_03700	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AO080_03710	COG0089	rRNA binding
AO080_03715	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AO080_03720	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AO080_03725	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AO080_03730	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AO080_03735	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AO080_03740	COG0255	Belongs to the universal ribosomal protein uL29 family
AO080_03750	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AO080_03755	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AO080_03760	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AO080_03765	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AO080_03770	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AO080_03775	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AO080_03780	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AO080_03785	COG1841	ribosomal large subunit assembly
AO080_03790	COG0200	Binds to the 23S rRNA
AO080_03805	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AO080_03810	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AO080_03820	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AO080_03825	COG0202	RNA polymerase activity
AO080_03830	COG0203	ribosomal protein L17
AO080_03855	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AO080_03870	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AO080_03895	COG0583	DNA-binding transcription factor activity
AO080_03900	COG0114	fumarate hydratase activity
AO080_03905	COG1053	succinate dehydrogenase
AO080_03910	COG0471	metal ion transport
AO080_03915	COG0039	L-malate dehydrogenase activity
AO080_03920	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AO080_03925	COG0215	cysteine-tRNA ligase activity
AO080_03930	COG0626	cystathionine gamma-synthase activity
AO080_03935	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AO080_03940	COG1464	Belongs to the NlpA lipoprotein family
AO080_03945	COG1854	S-ribosylhomocysteine lyase activity
AO080_03950	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AO080_03955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AO080_03965	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AO080_03970	COG0250	Participates in transcription elongation, termination and antitermination
AO080_03975	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AO080_03980	COG0081	regulation of translation
AO080_03985	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AO080_03990	COG0222	ribosome binding
AO080_04000	COG1121	(ABC) transporter
AO080_04005	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AO080_04010	COG0803	Belongs to the bacterial solute-binding protein 9 family
AO080_04015	COG1252	NADH dehydrogenase
AO080_04025	COG1122	ATPase activity
AO080_04030	COG1122	ATPase activity
AO080_04040	COG0101	tRNA pseudouridine synthase activity
AO080_04045	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AO080_04060	COG4221	oxidoreductase activity
AO080_04085	COG0028	Belongs to the TPP enzyme family
AO080_04095	COG1573	uracil-dna glycosylase
AO080_04120	COG0671	phosphoesterase, PA-phosphatase related
AO080_04130	COG2814	Major facilitator Superfamily
AO080_04135	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AO080_04140	COG1660	Displays ATPase and GTPase activities
AO080_04145	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AO080_04150	COG1481	regulation of sporulation
AO080_04155	COG0740	serine-type endopeptidase activity
AO080_04170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AO080_04170	COG1263	PTS System
AO080_04180	COG1914	H( )-stimulated, divalent metal cation uptake system
AO080_04200	COG4974	Belongs to the 'phage' integrase family
AO080_04260	COG0489	protein tyrosine kinase activity
AO080_04265	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AO080_04290	COG1216	Glycosyl transferase, family 2
AO080_04295	COG0438	transferase activity, transferring glycosyl groups
AO080_04300	COG0728	peptidoglycan biosynthetic process
AO080_04310	COG1316	TRANSCRIPTIONal
AO080_04315	COG4464	protein tyrosine phosphatase activity
AO080_04345	COG0039	L-malate dehydrogenase activity
AO080_04350	COG0028	Belongs to the TPP enzyme family
AO080_04355	COG3527	Alpha-acetolactate decarboxylase
AO080_04365	COG3942	CHAP domain
AO080_04365	COG1388	LysM domain
AO080_04370	COG0791	NLP P60 protein
AO080_04380	COG0756	dUTP diphosphatase activity
AO080_04390	COG4956	integral membrane protein (PIN domain superfamily)
AO080_04400	COG0653	protein targeting
AO080_04405	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AO080_04425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AO080_04435	COG1733	regulation of RNA biosynthetic process
AO080_04440	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AO080_04445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AO080_04445	COG0072	phenylalanine-tRNA ligase activity
AO080_04450	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AO080_04455	COG0514	ATP-dependent DNA helicase (RecQ)
AO080_04460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AO080_04470	COG0768	penicillin binding
AO080_04475	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AO080_04490	COG1940	carbohydrate kinase activity
AO080_04505	COG3942	CHAP domain
AO080_04525	COG0584	glycerophosphoryl diester phosphodiesterase
AO080_04530	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AO080_04535	COG0789	Transcriptional regulator
AO080_04540	COG0174	glutamine synthetase
AO080_04565	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AO080_04570	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AO080_04590	COG1132	(ABC) transporter
AO080_04595	COG0778	Nitroreductase
AO080_04600	COG1169	isochorismate synthase
AO080_04605	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AO080_04610	COG0596	Alpha beta hydrolase
AO080_04615	COG4948	Mandelate Racemase Muconate Lactonizing
AO080_04620	COG0006	proline dipeptidase activity
AO080_04635	COG0737	Belongs to the 5'-nucleotidase family
AO080_04640	COG4470	Protein conserved in bacteria
AO080_04645	COG0647	UMP catabolic process
AO080_04650	COG4166	transmembrane transport
AO080_04655	COG0673	inositol 2-dehydrogenase activity
AO080_04680	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AO080_04685	COG0573	inorganic phosphate transmembrane transporter activity
AO080_04690	COG0581	inorganic phosphate transmembrane transporter activity
AO080_04695	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AO080_04700	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AO080_04705	COG0704	Plays a role in the regulation of phosphate uptake
AO080_04710	COG2137	regulation of response to DNA damage stimulus
AO080_04745	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AO080_04755	COG5506	Protein of unknown function (DUF1694)
AO080_04765	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AO080_04885	COG1272	protein, Hemolysin III
AO080_04915	COG0525	valine-tRNA ligase activity
AO080_04925	COG0285	dihydrofolate synthase activity
AO080_04945	COG0488	(ABC) transporter
AO080_04950	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AO080_04955	COG0459	protein refolding
AO080_04960	COG0531	amino acid
AO080_04970	COG1181	Belongs to the D-alanine--D-alanine ligase family
AO080_04975	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AO080_04980	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AO080_04990	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AO080_04995	COG1713	HD superfamily hydrolase involved in NAD metabolism
AO080_05000	COG0799	negative regulation of ribosome biogenesis
AO080_05005	COG2226	methyltransferase
AO080_05010	COG1323	Belongs to the UPF0348 family
AO080_05020	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AO080_05025	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AO080_05125	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AO080_05130	COG3764	Sortase (surface protein transpeptidase)
AO080_05135	COG0363	glucosamine-6-phosphate deaminase activity
AO080_05140	COG0776	regulation of translation
AO080_05150	COG0577	efflux transmembrane transporter activity
AO080_05155	COG1136	(ABC) transporter
AO080_05170	COG4720	Psort location CytoplasmicMembrane, score
AO080_05175	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AO080_05180	COG1570	exodeoxyribonuclease VII activity
AO080_05190	COG0142	geranyltranstransferase activity
AO080_05195	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AO080_05200	COG1438	arginine binding
AO080_05205	COG0497	DNA recombination
AO080_05215	COG0194	GDP metabolic process
AO080_05225	COG0586	Pfam SNARE associated Golgi protein
AO080_05230	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AO080_05235	COG1098	S1 RNA binding domain
AO080_05350	COG4684	Psort location CytoplasmicMembrane, score
AO080_05355	COG1271	oxidase subunit
AO080_05360	COG1294	oxidase, subunit
AO080_05365	COG4988	ABC transporter
AO080_05370	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AO080_05375	COG1388	LysM domain
AO080_05375	COG1705	Flagellar rod assembly protein muramidase FlgJ
AO080_05380	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AO080_05395	COG0494	nUDIX hydrolase
AO080_05405	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AO080_05410	COG0346	lactoylglutathione lyase activity
AO080_05415	COG0400	carboxylic ester hydrolase activity
AO080_05425	COG0741	lytic transglycosylase activity
AO080_05445	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AO080_05450	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AO080_05455	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AO080_05465	COG4120	Belongs to the binding-protein-dependent transport system permease family
AO080_05475	COG0038	chloride channel
AO080_05480	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AO080_05485	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AO080_05490	COG1307	EDD domain protein, DegV family
AO080_05495	COG2190	(PTS) system
AO080_05495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AO080_05495	COG1263	PTS System
AO080_05515	COG2003	Belongs to the UPF0758 family
AO080_05520	COG1077	Cell shape determining protein MreB Mrl
AO080_05525	COG1792	Involved in formation and maintenance of cell shape
AO080_05530	COG3338	carbonate dehydratase activity
AO080_05540	COG0765	amino acid transport
AO080_05545	COG1126	abc transporter atp-binding protein
AO080_05560	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AO080_05565	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AO080_05570	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AO080_05575	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AO080_05585	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AO080_05595	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AO080_05600	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AO080_05605	COG0138	bifunctional purine biosynthesis protein purh
AO080_05610	COG0151	Belongs to the GarS family
AO080_05615	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AO080_05630	COG0446	pyridine nucleotide-disulphide oxidoreductase
AO080_05650	COG0833	amino acid
AO080_05660	COG2264	protein methyltransferase activity
AO080_05665	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AO080_05675	COG2001	Belongs to the MraZ family
AO080_05680	COG0275	rRNA processing
AO080_05695	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AO080_05700	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AO080_05705	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AO080_05710	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AO080_05715	COG0849	cell division
AO080_05725	COG1799	cell septum assembly
AO080_05740	COG3599	regulation of cell shape
AO080_05760	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AO080_05765	COG0217	transcriptional regulatory protein
AO080_05770	COG2252	PERMEase
AO080_05775	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AO080_05815	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AO080_05820	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AO080_05825	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AO080_05830	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AO080_05830	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AO080_05835	COG0631	protein serine/threonine phosphatase activity
AO080_05840	COG2815	serine threonine protein kinase
AO080_05840	COG0515	serine threonine protein kinase
AO080_05845	COG1162	GTPase activity
AO080_05850	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AO080_05860	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AO080_05870	COG1461	Dihydroxyacetone kinase
AO080_05885	COG0438	transferase activity, transferring glycosyl groups
AO080_05895	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AO080_05900	COG0416	fatty acid biosynthetic process
AO080_05905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AO080_05910	COG0571	ribonuclease III activity
AO080_05915	COG1196	nuclear chromosome segregation
AO080_05920	COG0552	protein localization to endoplasmic reticulum
AO080_05930	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AO080_05945	COG0228	four-way junction DNA binding
AO080_05950	COG0582	viral genome integration into host DNA
AO080_06210	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AO080_06215	COG0336	Belongs to the RNA methyltransferase TrmD family
AO080_06220	COG0335	large ribosomal subunit rRNA binding
AO080_06230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AO080_06235	COG1942	4-Oxalocrotonate Tautomerase
AO080_06240	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AO080_06250	COG1428	Deoxynucleoside kinase
AO080_06255	COG1970	mechanosensitive ion channel activity
AO080_06260	COG0561	phosphatase activity
AO080_06325	COG3853	Toxic anion resistance protein (TelA)
AO080_06330	COG1393	Belongs to the ArsC family
AO080_06335	COG4862	establishment of competence for transformation
AO080_06340	COG2723	6-phospho-beta-galactosidase activity
AO080_06345	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AO080_06350	COG1447	Phosphotransferase system cellobiose-specific component IIA
AO080_06355	COG2723	6-phospho-beta-galactosidase activity
AO080_06360	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AO080_06370	COG1164	Oligoendopeptidase f
AO080_06375	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AO080_06390	COG1609	Transcriptional regulator
AO080_06395	COG0006	proline dipeptidase activity
AO080_06475	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AO080_06480	COG3425	synthase
AO080_06495	COG0860	N-Acetylmuramoyl-L-alanine amidase
AO080_06500	COG0124	histidyl-tRNA synthetase
AO080_06505	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AO080_06520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AO080_06525	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AO080_06530	COG1610	YqeY-like protein
AO080_06535	COG1702	phosphate starvation-inducible protein PhoH
AO080_06540	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AO080_06545	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AO080_06550	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AO080_06555	COG1381	Involved in DNA repair and RecF pathway recombination
AO080_06565	COG0752	glycyl-tRNA synthetase alpha subunit
AO080_06570	COG0751	glycine-tRNA ligase activity
AO080_06730	COG1783	phage Terminase large subunit
AO080_06755	COG0228	four-way junction DNA binding
AO080_06840	COG2706	6-phosphogluconolactonase activity
AO080_06845	COG0628	permease
AO080_06855	COG1674	ftsk spoiiie
AO080_06865	COG4152	abc transporter atp-binding protein
AO080_06870	COG1668	transmembrane transport
AO080_06880	COG0322	excinuclease ABC activity
AO080_06885	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AO080_06890	COG1739	Uncharacterized protein family UPF0029
AO080_06910	COG0516	GMP reductase activity
AO080_06910	COG0517	IMP dehydrogenase activity
AO080_06915	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AO080_06920	COG0632	four-way junction helicase activity
AO080_06925	COG2255	four-way junction helicase activity
AO080_06930	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AO080_06965	COG0343	queuine tRNA-ribosyltransferase activity
AO080_06970	COG1862	Preprotein translocase
AO080_06975	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AO080_06980	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AO080_06985	COG0513	Belongs to the DEAD box helicase family
AO080_06990	COG1929	Belongs to the glycerate kinase type-1 family
AO080_06995	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AO080_07015	COG3906	Belongs to the UPF0473 family
AO080_07020	COG1555	photosystem II stabilization
AO080_07020	COG1596	polysaccharide export
AO080_07035	COG1466	dna polymerase III delta subunit
AO080_07040	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AO080_07045	COG0268	Binds directly to 16S ribosomal RNA
AO080_07070	COG0544	peptidyl-prolyl cis-trans isomerase activity
AO080_07075	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AO080_07080	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AO080_07100	COG1193	negative regulation of DNA recombination
AO080_07120	COG3118	belongs to the thioredoxin family
AO080_07125	COG0187	DNA topoisomerase II activity
AO080_07130	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AO080_07135	COG3527	Alpha-acetolactate decarboxylase
AO080_07140	COG1473	amidohydrolase
AO080_07155	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AO080_07175	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AO080_07180	COG3201	nicotinamide mononucleotide transporter
AO080_07215	COG0028	Belongs to the TPP enzyme family
AO080_07225	COG0277	FAD linked oxidase domain protein
AO080_07230	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AO080_07250	COG2801	Transposase and inactivated derivatives
AO080_07260	COG0277	FAD linked oxidase domain protein
AO080_07265	COG0436	Aminotransferase
AO080_07280	COG1464	Belongs to the NlpA lipoprotein family
AO080_07290	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AO080_07295	COG0351	phosphomethylpyrimidine kinase
AO080_07300	COG0352	thiamine-phosphate diphosphorylase activity
AO080_07325	COG1028	Short-chain dehydrogenase reductase Sdr
AO080_07335	COG1940	carbohydrate kinase activity
AO080_07410	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AO080_07415	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AO080_07430	COG2357	RelA SpoT domain protein
AO080_07435	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AO080_07440	COG0564	pseudouridine synthase activity
AO080_07445	COG2239	Acts as a magnesium transporter
AO080_07450	COG2814	Major facilitator Superfamily
AO080_07465	COG2801	Transposase and inactivated derivatives
AO080_07505	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AO080_07515	COG1846	Transcriptional regulator
AO080_07520	COG0456	acetyltransferase
AO080_07575	COG1279	arginine transmembrane transporter activity
AO080_07595	COG2801	Transposase and inactivated derivatives
AO080_07605	COG0384	phenazine biosynthesis protein PhzF
AO080_07615	COG1621	beta-fructofuranosidase activity
AO080_07635	COG2409	Drug exporters of the RND superfamily
AO080_07635	COG1033	growth of symbiont in host cell
AO080_07650	COG0583	DNA-binding transcription factor activity
AO080_07655	COG1063	alcohol dehydrogenase
AO080_07670	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AO080_07685	COG0738	Major facilitator superfamily
AO080_07690	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AO080_07710	COG1304	FMN binding
AO080_07725	COG0779	Required for maturation of 30S ribosomal subunits
AO080_07730	COG0195	Participates in both transcription termination and antitermination
AO080_07735	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AO080_07745	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AO080_07750	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AO080_07755	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AO080_07760	COG1252	NADH dehydrogenase
AO080_07770	COG0196	riboflavin kinase activity
AO080_07780	COG3142	Participates in the control of copper homeostasis
AO080_07800	COG1307	EDD domain protein, DegV family
AO080_07805	COG1307	EDD domain protein, DegV family
AO080_07810	COG2755	lipolytic protein G-D-S-L family
AO080_07820	COG4479	Belongs to the UPF0346 family
AO080_07830	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AO080_07835	COG0758	DNA mediated transformation
AO080_07840	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AO080_07845	COG4974	Belongs to the 'phage' integrase family
AO080_07855	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AO080_07860	COG1227	inorganic diphosphatase activity
AO080_07875	COG3448	diguanylate cyclase activity
AO080_07875	COG4175	Glycine betaine
AO080_07885	COG0446	pyridine nucleotide-disulphide oxidoreductase
AO080_07890	COG1464	Belongs to the NlpA lipoprotein family
AO080_07895	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AO080_07900	COG1597	lipid kinase activity
AO080_07905	COG1011	Hydrolase
AO080_07940	COG0242	peptide deformylase activity
AO080_07945	COG4476	Belongs to the UPF0223 family
AO080_07950	COG0483	inositol monophosphate 1-phosphatase activity
AO080_07960	COG0772	Belongs to the SEDS family
AO080_07965	COG4471	UPF0298 protein
AO080_07970	COG0742	ribosomal rna small subunit methyltransferase
AO080_07975	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AO080_07980	COG3480	Lon protease (S16) C-terminal proteolytic domain
AO080_07985	COG0477	Major facilitator Superfamily
AO080_07995	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AO080_08000	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AO080_08005	COG0358	DNA primase activity
AO080_08010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AO080_08040	COG0745	RESPONSE REGULATOR receiver
AO080_08045	COG5002	protein histidine kinase activity
AO080_08050	COG0572	uridine kinase
AO080_08055	COG1363	Peptidase, m42
AO080_08060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AO080_08070	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AO080_08075	COG0670	Belongs to the BI1 family
AO080_08080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AO080_08080	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AO080_08085	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AO080_08090	COG0237	dephospho-CoA kinase activity
AO080_08100	COG1484	DNA-dependent DNA replication
AO080_08115	COG0745	RESPONSE REGULATOR receiver
AO080_08120	COG5002	protein histidine kinase activity
AO080_08130	COG1705	Flagellar rod assembly protein muramidase FlgJ
AO080_08130	COG3942	CHAP domain
AO080_08140	COG0531	amino acid
AO080_08155	COG0706	membrane insertase activity
AO080_08165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AO080_08175	COG1304	FMN binding
AO080_08195	COG1199	ATP-dependent helicase activity
AO080_08195	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AO080_08205	COG0017	Asparaginyl-tRNA synthetase
AO080_08210	COG3935	DnaD domain protein
AO080_08220	COG3331	DNA recombination
AO080_08225	COG4474	Belongs to the UPF0398 family
AO080_08230	COG3599	regulation of cell shape
AO080_08240	COG0116	Belongs to the methyltransferase superfamily
AO080_08250	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AO080_08270	COG0556	nucleotide-excision repair
AO080_08280	COG0439	Biotin carboxylase
AO080_08285	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AO080_08290	COG0825	malonyl-CoA metabolic process
AO080_08295	COG3104	oligopeptide transport
AO080_08300	COG0363	glucosamine-6-phosphate deaminase activity
AO080_08310	COG0537	adenosine 5'-monophosphoramidase activity
AO080_08315	COG1131	(ABC) transporter
AO080_08325	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AO080_08330	COG1719	4-vinyl reductase, 4VR
AO080_08335	COG1397	ADP-ribosylglycohydrolase
AO080_08360	COG0446	pyridine nucleotide-disulphide oxidoreductase
AO080_08365	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
AO080_08370	COG1349	DNA-binding transcription factor activity
AO080_08375	COG1105	Belongs to the carbohydrate kinase PfkB family
AO080_08380	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AO080_08380	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AO080_08380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AO080_08390	COG1609	Transcriptional regulator
AO080_08410	COG0306	phosphate transporter
AO080_08425	COG2723	6-phospho-beta-galactosidase activity
AO080_08445	COG0531	amino acid
AO080_08455	COG0481	GTPase activity
AO080_08485	COG1028	Short-chain dehydrogenase reductase Sdr
AO080_08490	COG4708	membrane
AO080_08500	COG0531	amino acid
AO080_08510	COG4221	oxidoreductase activity
AO080_08520	COG0281	malic enzyme
AO080_08530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AO080_08545	COG1136	(ABC) transporter
AO080_08550	COG0577	efflux transmembrane transporter activity
AO080_08570	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AO080_08575	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AO080_08595	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AO080_08605	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AO080_08610	COG2384	SAM-dependent methyltransferase
AO080_08615	COG0071	Belongs to the small heat shock protein (HSP20) family
AO080_08620	COG0457	Tetratricopeptide repeat
AO080_08655	COG0419	ATPase involved in DNA repair
AO080_08660	COG0420	3'-5' exonuclease activity
AO080_08670	COG2807	transmembrane transport
AO080_08675	COG4720	Psort location CytoplasmicMembrane, score
AO080_08680	COG0351	phosphomethylpyrimidine kinase
AO080_08690	COG1160	GTP binding
AO080_08695	COG0539	negative regulation of cytoplasmic translation
AO080_08700	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AO080_08710	COG0514	ATP-dependent DNA helicase (RecQ)
AO080_08720	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AO080_08735	COG1187	pseudouridine synthase activity
AO080_08740	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AO080_08745	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AO080_08760	COG2996	Protein conserved in bacteria
AO080_08770	COG0475	glutathione-regulated potassium exporter activity
AO080_08780	COG1490	D-aminoacyl-tRNA deacylase activity
AO080_08785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AO080_08790	COG0587	DNA-directed DNA polymerase activity
AO080_08800	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AO080_08805	COG0488	(ABC) transporter
AO080_08810	COG0617	tRNA 3'-terminal CCA addition
AO080_08825	COG1136	(ABC) transporter
AO080_08840	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AO080_08845	COG0004	ammonium transporteR
AO080_08855	COG0366	Alpha amylase catalytic
AO080_08855	COG5263	repeat protein
AO080_08860	COG1316	TRANSCRIPTIONal
AO080_08865	COG1216	Glycosyl transferase, family 2
AO080_08880	COG1216	Glycosyl transferase, family 2
AO080_08890	COG0438	transferase activity, transferring glycosyl groups
AO080_08895	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AO080_08900	COG0489	protein tyrosine kinase activity
AO080_08915	COG0233	cytoplasmic translational termination
AO080_08925	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AO080_08930	COG0052	Belongs to the universal ribosomal protein uS2 family
AO080_08935	COG2827	Endonuclease containing a URI domain
AO080_08940	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AO080_08945	COG0204	Acyl-transferase
AO080_08950	COG3883	PFAM NLP P60 protein
AO080_08950	COG0791	NLP P60 protein
AO080_08965	COG3763	UPF0154 protein
AO080_08970	COG4224	UPF0291 protein
AO080_08975	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AO080_08995	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AO080_08995	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AO080_09000	COG1234	tRNA 3'-trailer cleavage
AO080_09015	COG0484	heat shock protein binding
AO080_09020	COG0443	Heat shock 70 kDa protein
AO080_09030	COG1420	regulation of RNA biosynthetic process
AO080_09060	COG1216	Glycosyl transferase, family 2
AO080_09070	COG0463	Glycosyl transferase, family 2
AO080_09080	COG1705	Flagellar rod assembly protein muramidase FlgJ
AO080_09095	COG0562	UDP-galactopyranose mutase
AO080_09125	COG0024	Methionine aminopeptidase
AO080_09150	COG1705	Flagellar rod assembly protein muramidase FlgJ
AO080_09150	COG1388	LysM domain
AO080_09170	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AO080_09180	COG1682	transport, permease protein
AO080_09185	COG1134	teichoic acid transport
AO080_09185	COG1388	LysM domain
AO080_09190	COG1063	alcohol dehydrogenase
AO080_09195	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AO080_09200	COG3475	LICD family
AO080_09220	COG0463	Glycosyl transferase, family 2
AO080_09225	COG2246	polysaccharide biosynthetic process
AO080_09230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AO080_09240	COG2801	Transposase and inactivated derivatives
AO080_09265	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AO080_09380	COG0463	Glycosyl transferase, family 2
AO080_09395	COG3706	GGDEF domain
AO080_09445	COG2309	aminopeptidase activity
AO080_09460	COG0564	pseudouridine synthase activity
AO080_09465	COG1278	Cold shock
AO080_09475	COG2814	Major facilitator Superfamily
AO080_09480	COG0741	lytic transglycosylase activity
AO080_09490	COG3973	AAA domain
AO080_09500	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AO080_09505	COG1546	Belongs to the CinA family
AO080_09505	COG1058	Belongs to the CinA family
AO080_09510	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AO080_09515	COG1426	Protein conserved in bacteria
AO080_09520	COG0612	Peptidase, M16
AO080_09525	COG0612	Peptidase, M16
AO080_09560	COG4717	serine-type aminopeptidase activity
AO080_09570	COG3679	Belongs to the UPF0342 family
AO080_09575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AO080_09580	COG1438	arginine binding
AO080_09605	COG0018	arginyl-trna synthetase
AO080_09620	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AO080_09630	COG1121	(ABC) transporter
AO080_09650	COG1597	lipid kinase activity
AO080_09655	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AO080_09660	COG0154	amidase activity
AO080_09665	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AO080_09670	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AO080_09670	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AO080_09695	COG1695	Transcriptional regulator
AO080_09705	COG1914	H( )-stimulated, divalent metal cation uptake system
AO080_09725	COG0667	Aldo Keto reductase
AO080_09730	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AO080_09735	COG4721	ABC-type cobalt transport system, permease component
AO080_09740	COG1122	ATPase activity
AO080_09755	COG0710	3-dehydroquinate dehydratase activity
AO080_09760	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AO080_09765	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AO080_09770	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AO080_09775	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AO080_09780	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AO080_09785	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AO080_09800	COG4684	Psort location CytoplasmicMembrane, score
AO080_09805	COG0436	Aminotransferase
AO080_09825	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AO080_09830	COG0436	Aminotransferase
AO080_09835	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AO080_09840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AO080_09850	COG2171	N-acyltransferase activity
AO080_09860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AO080_09865	COG0527	aspartate kinase activity
AO080_09875	COG1609	Transcriptional regulator
AO080_09880	COG0083	homoserine kinase activity
AO080_09895	COG1321	iron dependent repressor
AO080_09925	COG0513	Belongs to the DEAD box helicase family
AO080_09930	COG0673	inositol 2-dehydrogenase activity
AO080_09935	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AO080_09950	COG2801	Transposase and inactivated derivatives
AO080_09960	COG0501	Belongs to the peptidase M48B family
AO080_09965	COG1704	LemA family
AO080_09975	COG4115	mRNA cleavage
AO080_09980	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AO080_09995	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AO080_10005	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AO080_10010	COG0439	Biotin carboxylase
AO080_10025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AO080_10030	COG1028	Short-chain dehydrogenase reductase Sdr
AO080_10035	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AO080_10040	COG2070	2-Nitropropane dioxygenase
AO080_10045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AO080_10050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AO080_10055	COG1846	Transcriptional regulator
AO080_10060	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AO080_10070	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AO080_10075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AO080_10085	COG0505	Belongs to the CarA family
AO080_10095	COG0564	pseudouridine synthase activity
AO080_10105	COG0328	RNA-DNA hybrid ribonuclease activity
AO080_10115	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AO080_10120	COG1113	amino acid transport
AO080_10165	COG2801	Transposase and inactivated derivatives
AO080_10170	COG1396	sequence-specific DNA binding
AO080_10190	COG4974	Belongs to the 'phage' integrase family
AO080_10205	COG0656	L-ascorbic acid biosynthetic process
AO080_10215	COG1454	alcohol dehydrogenase
AO080_10215	COG1012	belongs to the aldehyde dehydrogenase family
AO080_10220	COG0105	UTP biosynthetic process
AO080_10230	COG0583	DNA-binding transcription factor activity
AO080_10235	COG0126	phosphoglycerate kinase activity
AO080_10285	COG0588	phosphoglycerate mutase activity
AO080_10295	COG3716	PTS system mannose fructose sorbose family IID component
AO080_10300	COG3715	PTS system
AO080_10315	COG1397	ADP-ribosylglycohydrolase
AO080_10380	COG1368	sulfuric ester hydrolase activity
AO080_10395	COG0438	transferase activity, transferring glycosyl groups
AO080_10400	COG0438	transferase activity, transferring glycosyl groups
AO080_10405	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AO080_10410	COG0284	orotidine-5'-phosphate decarboxylase activity
AO080_10415	COG0167	dihydroorotate dehydrogenase activity
AO080_10420	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AO080_10425	COG0505	Belongs to the CarA family
AO080_10430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AO080_10435	COG0540	Belongs to the ATCase OTCase family
AO080_10455	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AO080_10460	COG4856	YbbR-like protein
AO080_10475	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AO080_10490	COG0802	atpase or kinase
AO080_10495	COG0280	phosphate acetyltransferase
AO080_10500	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AO080_10510	COG2076	Multidrug Resistance protein
AO080_10515	COG2076	Multidrug Resistance protein
AO080_10525	COG0765	amino acid transport
AO080_10530	COG2814	Major facilitator Superfamily
AO080_10545	COG0557	exoribonuclease II activity
AO080_10560	COG0154	amidase activity
AO080_10580	COG2801	Transposase and inactivated derivatives
AO080_10590	COG0149	triose-phosphate isomerase activity
AO080_10595	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AO080_10600	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AO080_10610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AO080_10615	COG0492	ferredoxin-NADP+ reductase activity
AO080_10645	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AO080_10650	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AO080_10655	COG1950	PFAM Membrane protein of
AO080_10665	COG0589	response to stress
AO080_10675	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AO080_10685	COG1177	transmembrane transport
AO080_10690	COG1176	ABC-type spermidine putrescine transport system, permease component I
AO080_10695	COG3842	ATPase activity
AO080_10705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AO080_10710	COG0049	tRNA binding
AO080_10715	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AO080_10720	COG4608	Belongs to the ABC transporter superfamily
AO080_10725	COG0444	Belongs to the ABC transporter superfamily
AO080_10730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AO080_10735	COG0601	transmembrane transport
AO080_10745	COG0460	homoserine dehydrogenase
AO080_10750	COG0626	cystathionine gamma-synthase activity
AO080_10755	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AO080_10770	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AO080_10775	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AO080_10790	COG1302	Protein conserved in bacteria
AO080_10795	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AO080_10805	COG2017	converts alpha-aldose to the beta-anomer
AO080_10815	COG4975	Glucose uptake
AO080_10820	COG3850	Histidine kinase
AO080_10820	COG5002	protein histidine kinase activity
AO080_10825	COG0745	RESPONSE REGULATOR receiver
AO080_10830	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AO080_10835	COG0402	S-adenosylhomocysteine deaminase activity
AO080_10840	COG0673	inositol 2-dehydrogenase activity
AO080_10845	COG0741	lytic transglycosylase activity
AO080_10865	COG0668	transmembrane transport
AO080_10875	COG1126	abc transporter atp-binding protein
AO080_10995	COG0516	GMP reductase activity
AO080_11025	COG2801	Transposase and inactivated derivatives
AO080_11045	COG0738	Major facilitator superfamily
AO080_11050	COG1869	D-ribose catabolic process
AO080_11075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AO080_11090	COG1609	Transcriptional regulator
AO080_11125	COG2223	nitrite transmembrane transporter activity
AO080_11135	COG0318	PFAM AMP-dependent synthetase and ligase
AO080_11145	COG1116	anion transmembrane transporter activity
AO080_11150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AO080_11160	COG0285	dihydrofolate synthase activity
AO080_11165	COG0302	gtp cyclohydrolase
AO080_11170	COG0302	gtp cyclohydrolase
AO080_11170	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AO080_11185	COG0561	phosphatase activity
AO080_11200	COG1464	Belongs to the NlpA lipoprotein family
AO080_11205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AO080_11210	COG0800	Aldolase
AO080_11215	COG1904	glucuronate isomerase
AO080_11225	COG0246	Mannitol dehydrogenase
AO080_11240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AO080_11255	COG1609	Transcriptional regulator
AO080_11285	COG0577	efflux transmembrane transporter activity
AO080_11290	COG1136	(ABC) transporter
AO080_11295	COG3759	membrane
AO080_11315	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AO080_11320	COG2235	arginine
AO080_11330	COG2217	Heavy metal translocating P-type atpase
AO080_11400	COG0438	transferase activity, transferring glycosyl groups
AO080_11455	COG2814	Major facilitator Superfamily
AO080_11460	COG2217	Heavy metal translocating P-type atpase
AO080_11480	COG1309	transcriptional regulator
AO080_11500	COG3711	transcriptional antiterminator
AO080_11505	COG2723	6-phospho-beta-galactosidase activity
AO080_11510	COG1940	carbohydrate kinase activity
AO080_11530	COG2183	response to ionizing radiation
AO080_11545	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AO080_11550	COG1040	competence protein
AO080_11560	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AO080_11630	COG2176	DNA-directed DNA polymerase activity
AO080_11635	COG0442	prolyl-tRNA aminoacylation
AO080_11640	COG0750	zinc metalloprotease
AO080_11645	COG4589	Belongs to the CDS family
AO080_11650	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AO080_11655	COG0561	phosphatase activity
AO080_11660	COG2246	polysaccharide biosynthetic process
AO080_11685	COG1811	Na channel or pump
AO080_11690	COG1979	alcohol dehydrogenase
AO080_11700	COG1174	glycine betaine transport
AO080_11710	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AO080_11740	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AO080_11740	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AO080_11780	COG2261	transglycosylase associated protein
AO080_11810	COG0783	Belongs to the Dps family
AO080_11815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AO080_11835	COG1250	3-hydroxyacyl-CoA dehydrogenase
AO080_11855	COG2801	Transposase and inactivated derivatives
AO080_11875	COG1028	Short-chain dehydrogenase reductase Sdr
AO080_11890	COG5039	Polysaccharide pyruvyl transferase
AO080_11895	COG2814	Major facilitator Superfamily
AO080_11935	COG2261	transglycosylase associated protein
AO080_11965	COG0783	Belongs to the Dps family
AO080_12030	COG1063	alcohol dehydrogenase
AO080_12035	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AO080_12130	COG1028	Short-chain dehydrogenase reductase Sdr
AO080_12165	COG1028	Short-chain dehydrogenase reductase Sdr
AO080_12200	COG1028	Short-chain dehydrogenase reductase Sdr
AO080_12215	COG3729	General stress protein
AO080_12235	COG3729	General stress protein
AO080_12255	COG1176	ABC-type spermidine putrescine transport system, permease component I
AO080_12260	COG1177	transmembrane transport
AO080_12265	COG3842	ATPase activity