locus-tag	class	description
CHR48_00006	COG0765	amino acid transport
CHR48_00007	COG1126	abc transporter atp-binding protein
CHR48_00009	COG0668	transmembrane transport
CHR48_00013	COG0741	lytic transglycosylase activity
CHR48_00014	COG0673	inositol 2-dehydrogenase activity
CHR48_00015	COG0402	S-adenosylhomocysteine deaminase activity
CHR48_00016	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CHR48_00017	COG0745	RESPONSE REGULATOR receiver
CHR48_00018	COG5002	protein histidine kinase activity
CHR48_00018	COG3850	Histidine kinase
CHR48_00019	COG4975	Glucose uptake
CHR48_00021	COG2017	converts alpha-aldose to the beta-anomer
CHR48_00023	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CHR48_00024	COG1302	Protein conserved in bacteria
CHR48_00027	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CHR48_00028	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CHR48_00031	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CHR48_00032	COG0626	cystathionine gamma-synthase activity
CHR48_00033	COG0460	homoserine dehydrogenase
CHR48_00035	COG0601	transmembrane transport
CHR48_00036	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR48_00037	COG0444	Belongs to the ABC transporter superfamily
CHR48_00038	COG4608	Belongs to the ABC transporter superfamily
CHR48_00040	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CHR48_00041	COG0049	tRNA binding
CHR48_00042	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CHR48_00044	COG3842	ATPase activity
CHR48_00045	COG1176	ABC-type spermidine putrescine transport system, permease component I
CHR48_00046	COG1177	transmembrane transport
CHR48_00048	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CHR48_00050	COG0589	response to stress
CHR48_00052	COG1950	PFAM Membrane protein of
CHR48_00053	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CHR48_00054	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CHR48_00059	COG0492	ferredoxin-NADP+ reductase activity
CHR48_00060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CHR48_00062	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHR48_00063	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHR48_00064	COG0149	triose-phosphate isomerase activity
CHR48_00068	COG0154	amidase activity
CHR48_00071	COG0557	exoribonuclease II activity
CHR48_00074	COG2814	Major facilitator Superfamily
CHR48_00075	COG0765	amino acid transport
CHR48_00076	COG1126	abc transporter atp-binding protein
CHR48_00077	COG2076	Multidrug Resistance protein
CHR48_00078	COG2076	Multidrug Resistance protein
CHR48_00080	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CHR48_00081	COG0280	phosphate acetyltransferase
CHR48_00082	COG0802	atpase or kinase
CHR48_00085	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CHR48_00088	COG4856	YbbR-like protein
CHR48_00089	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CHR48_00094	COG0540	Belongs to the ATCase OTCase family
CHR48_00095	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CHR48_00096	COG0505	Belongs to the CarA family
CHR48_00097	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CHR48_00098	COG0167	dihydroorotate dehydrogenase activity
CHR48_00099	COG0284	orotidine-5'-phosphate decarboxylase activity
CHR48_00100	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CHR48_00101	COG0438	transferase activity, transferring glycosyl groups
CHR48_00102	COG0438	transferase activity, transferring glycosyl groups
CHR48_00105	COG1368	sulfuric ester hydrolase activity
CHR48_00117	COG1397	ADP-ribosylglycohydrolase
CHR48_00120	COG3715	PTS system
CHR48_00121	COG3716	PTS system mannose fructose sorbose family IID component
CHR48_00123	COG0588	phosphoglycerate mutase activity
CHR48_00133	COG0126	phosphoglycerate kinase activity
CHR48_00134	COG0583	DNA-binding transcription factor activity
CHR48_00136	COG0105	UTP biosynthetic process
CHR48_00137	COG1454	alcohol dehydrogenase
CHR48_00137	COG1012	belongs to the aldehyde dehydrogenase family
CHR48_00139	COG0656	L-ascorbic acid biosynthetic process
CHR48_00145	COG1113	amino acid transport
CHR48_00146	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CHR48_00148	COG0328	RNA-DNA hybrid ribonuclease activity
CHR48_00150	COG0564	pseudouridine synthase activity
CHR48_00152	COG0505	Belongs to the CarA family
CHR48_00154	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CHR48_00155	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CHR48_00157	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CHR48_00158	COG1846	Transcriptional regulator
CHR48_00159	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CHR48_00160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHR48_00161	COG2070	2-Nitropropane dioxygenase
CHR48_00162	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CHR48_00163	COG1028	Short-chain dehydrogenase reductase Sdr
CHR48_00164	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CHR48_00167	COG0439	Biotin carboxylase
CHR48_00168	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CHR48_00170	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CHR48_00173	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CHR48_00174	COG4115	mRNA cleavage
CHR48_00176	COG1704	LemA family
CHR48_00177	COG0501	Belongs to the peptidase M48B family
CHR48_00179	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CHR48_00180	COG0673	inositol 2-dehydrogenase activity
CHR48_00181	COG0513	Belongs to the DEAD box helicase family
CHR48_00185	COG3764	Sortase (surface protein transpeptidase)
CHR48_00186	COG1321	iron dependent repressor
CHR48_00189	COG0083	homoserine kinase activity
CHR48_00190	COG1609	Transcriptional regulator
CHR48_00192	COG0527	aspartate kinase activity
CHR48_00193	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CHR48_00195	COG2171	N-acyltransferase activity
CHR48_00197	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHR48_00198	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CHR48_00199	COG0436	Aminotransferase
CHR48_00200	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CHR48_00201	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CHR48_00208	COG1396	sequence-specific DNA binding
CHR48_00239	COG1783	phage Terminase large subunit
CHR48_00242	COG2801	Transposase and inactivated derivatives
CHR48_00247	COG0436	Aminotransferase
CHR48_00248	COG4684	Psort location CytoplasmicMembrane, score
CHR48_00251	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CHR48_00252	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CHR48_00253	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CHR48_00254	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CHR48_00255	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CHR48_00256	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CHR48_00257	COG0710	3-dehydroquinate dehydratase activity
CHR48_00260	COG0758	DNA mediated transformation
CHR48_00263	COG1122	ATPase activity
CHR48_00264	COG4721	ABC-type cobalt transport system, permease component
CHR48_00265	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CHR48_00266	COG0667	Aldo Keto reductase
CHR48_00270	COG1914	H( )-stimulated, divalent metal cation uptake system
CHR48_00272	COG1695	Transcriptional regulator
CHR48_00275	COG2936	dipeptidyl-peptidase activity
CHR48_00277	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CHR48_00277	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CHR48_00278	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHR48_00279	COG0154	amidase activity
CHR48_00280	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHR48_00281	COG1597	lipid kinase activity
CHR48_00285	COG1121	(ABC) transporter
CHR48_00287	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CHR48_00290	COG0018	arginyl-trna synthetase
CHR48_00294	COG1959	2 iron, 2 sulfur cluster binding
CHR48_00299	COG1438	arginine binding
CHR48_00300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CHR48_00301	COG3679	Belongs to the UPF0342 family
CHR48_00304	COG4717	serine-type aminopeptidase activity
CHR48_00308	COG0028	Belongs to the TPP enzyme family
CHR48_00311	COG0612	Peptidase, M16
CHR48_00312	COG0612	Peptidase, M16
CHR48_00313	COG1426	Protein conserved in bacteria
CHR48_00314	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CHR48_00315	COG1546	Belongs to the CinA family
CHR48_00315	COG1058	Belongs to the CinA family
CHR48_00316	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CHR48_00318	COG3973	AAA domain
CHR48_00319	COG1072	(Pantothenic acid kinase))
CHR48_00320	COG0741	lytic transglycosylase activity
CHR48_00321	COG2814	Major facilitator Superfamily
CHR48_00323	COG1278	Cold shock
CHR48_00324	COG0564	pseudouridine synthase activity
CHR48_00327	COG2309	aminopeptidase activity
CHR48_00337	COG2801	Transposase and inactivated derivatives
CHR48_00342	COG0024	Methionine aminopeptidase
CHR48_00347	COG0562	UDP-galactopyranose mutase
CHR48_00350	COG1705	Flagellar rod assembly protein muramidase FlgJ
CHR48_00352	COG0463	Glycosyl transferase, family 2
CHR48_00354	COG1216	Glycosyl transferase, family 2
CHR48_00360	COG1420	regulation of RNA biosynthetic process
CHR48_00362	COG0443	Heat shock 70 kDa protein
CHR48_00363	COG0484	heat shock protein binding
CHR48_00366	COG1234	tRNA 3'-trailer cleavage
CHR48_00367	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CHR48_00367	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CHR48_00371	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CHR48_00372	COG4224	UPF0291 protein
CHR48_00373	COG3763	UPF0154 protein
CHR48_00376	COG0791	NLP P60 protein
CHR48_00376	COG3883	PFAM NLP P60 protein
CHR48_00377	COG0204	Acyl-transferase
CHR48_00378	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CHR48_00379	COG2827	Endonuclease containing a URI domain
CHR48_00380	COG0052	Belongs to the universal ribosomal protein uS2 family
CHR48_00381	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CHR48_00383	COG0233	cytoplasmic translational termination
CHR48_00386	COG0489	protein tyrosine kinase activity
CHR48_00387	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CHR48_00388	COG0438	transferase activity, transferring glycosyl groups
CHR48_00390	COG1216	Glycosyl transferase, family 2
CHR48_00393	COG1216	Glycosyl transferase, family 2
CHR48_00396	COG1316	TRANSCRIPTIONal
CHR48_00397	COG0366	Alpha amylase catalytic
CHR48_00397	COG5263	repeat protein
CHR48_00399	COG0004	ammonium transporteR
CHR48_00401	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CHR48_00402	COG1266	CAAX protease self-immunity
CHR48_00406	COG0617	tRNA 3'-terminal CCA addition
CHR48_00407	COG0488	(ABC) transporter
CHR48_00408	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CHR48_00410	COG0587	DNA-directed DNA polymerase activity
CHR48_00411	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CHR48_00412	COG1490	D-aminoacyl-tRNA deacylase activity
CHR48_00414	COG0475	glutathione-regulated potassium exporter activity
CHR48_00416	COG2996	Protein conserved in bacteria
CHR48_00419	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CHR48_00420	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CHR48_00421	COG1187	pseudouridine synthase activity
CHR48_00424	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CHR48_00426	COG0514	ATP-dependent DNA helicase (RecQ)
CHR48_00428	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CHR48_00429	COG0539	negative regulation of cytoplasmic translation
CHR48_00430	COG1160	GTP binding
CHR48_00432	COG0351	phosphomethylpyrimidine kinase
CHR48_00433	COG4720	Psort location CytoplasmicMembrane, score
CHR48_00434	COG2807	transmembrane transport
CHR48_00436	COG0420	3'-5' exonuclease activity
CHR48_00437	COG0419	ATPase involved in DNA repair
CHR48_00446	COG0457	Tetratricopeptide repeat
CHR48_00447	COG0071	Belongs to the small heat shock protein (HSP20) family
CHR48_00448	COG2384	SAM-dependent methyltransferase
CHR48_00449	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CHR48_00451	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CHR48_00455	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CHR48_00456	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CHR48_00460	COG0577	efflux transmembrane transporter activity
CHR48_00461	COG1136	(ABC) transporter
CHR48_00465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHR48_00467	COG0281	malic enzyme
CHR48_00468	COG0583	DNA-binding transcription factor activity
CHR48_00469	COG4221	oxidoreductase activity
CHR48_00470	COG0531	amino acid
CHR48_00472	COG4708	membrane
CHR48_00473	COG1028	Short-chain dehydrogenase reductase Sdr
CHR48_00479	COG0481	GTPase activity
CHR48_00481	COG0531	amino acid
CHR48_00485	COG2723	6-phospho-beta-galactosidase activity
CHR48_00487	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CHR48_00489	COG0306	phosphate transporter
CHR48_00491	COG1609	Transcriptional regulator
CHR48_00493	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHR48_00493	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CHR48_00493	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CHR48_00494	COG1105	Belongs to the carbohydrate kinase PfkB family
CHR48_00495	COG1349	DNA-binding transcription factor activity
CHR48_00496	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CHR48_00497	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHR48_00502	COG1397	ADP-ribosylglycohydrolase
CHR48_00503	COG1719	4-vinyl reductase, 4VR
CHR48_00504	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CHR48_00506	COG1131	(ABC) transporter
CHR48_00507	COG0537	adenosine 5'-monophosphoramidase activity
CHR48_00509	COG0363	glucosamine-6-phosphate deaminase activity
CHR48_00510	COG3104	oligopeptide transport
CHR48_00511	COG0825	malonyl-CoA metabolic process
CHR48_00512	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CHR48_00513	COG0439	Biotin carboxylase
CHR48_00515	COG0556	nucleotide-excision repair
CHR48_00519	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CHR48_00521	COG0116	Belongs to the methyltransferase superfamily
CHR48_00523	COG3599	regulation of cell shape
CHR48_00524	COG4474	Belongs to the UPF0398 family
CHR48_00525	COG3331	DNA recombination
CHR48_00527	COG3935	DnaD domain protein
CHR48_00528	COG0017	Asparaginyl-tRNA synthetase
CHR48_00530	COG1199	ATP-dependent helicase activity
CHR48_00530	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CHR48_00534	COG1304	FMN binding
CHR48_00536	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CHR48_00537	COG1028	Short-chain dehydrogenase reductase Sdr
CHR48_00538	COG0706	membrane insertase activity
CHR48_00541	COG0531	amino acid
CHR48_00543	COG1705	Flagellar rod assembly protein muramidase FlgJ
CHR48_00543	COG3942	CHAP domain
CHR48_00545	COG5002	protein histidine kinase activity
CHR48_00546	COG0745	RESPONSE REGULATOR receiver
CHR48_00550	COG1484	DNA-dependent DNA replication
CHR48_00552	COG0237	dephospho-CoA kinase activity
CHR48_00553	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CHR48_00554	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHR48_00554	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHR48_00555	COG0670	Belongs to the BI1 family
CHR48_00556	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CHR48_00558	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHR48_00559	COG1363	Peptidase, m42
CHR48_00560	COG0572	uridine kinase
CHR48_00561	COG5002	protein histidine kinase activity
CHR48_00562	COG0745	RESPONSE REGULATOR receiver
CHR48_00568	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CHR48_00569	COG0358	DNA primase activity
CHR48_00570	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CHR48_00571	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CHR48_00573	COG0477	Major facilitator Superfamily
CHR48_00574	COG3480	Lon protease (S16) C-terminal proteolytic domain
CHR48_00575	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CHR48_00576	COG0742	ribosomal rna small subunit methyltransferase
CHR48_00577	COG4471	UPF0298 protein
CHR48_00578	COG0772	Belongs to the SEDS family
CHR48_00580	COG0483	inositol monophosphate 1-phosphatase activity
CHR48_00581	COG4476	Belongs to the UPF0223 family
CHR48_00582	COG0242	peptide deformylase activity
CHR48_00589	COG1011	Hydrolase
CHR48_00591	COG1597	lipid kinase activity
CHR48_00592	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CHR48_00593	COG1464	Belongs to the NlpA lipoprotein family
CHR48_00594	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHR48_00597	COG4175	Glycine betaine
CHR48_00597	COG3448	diguanylate cyclase activity
CHR48_00600	COG1227	inorganic diphosphatase activity
CHR48_00601	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CHR48_00603	COG4974	Belongs to the 'phage' integrase family
CHR48_00604	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CHR48_00605	COG0758	DNA mediated transformation
CHR48_00606	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CHR48_00608	COG4479	Belongs to the UPF0346 family
CHR48_00610	COG2755	lipolytic protein G-D-S-L family
CHR48_00611	COG1307	EDD domain protein, DegV family
CHR48_00612	COG1307	EDD domain protein, DegV family
CHR48_00613	COG2270	Major facilitator Superfamily
CHR48_00616	COG3142	Participates in the control of copper homeostasis
CHR48_00618	COG0196	riboflavin kinase activity
CHR48_00620	COG1252	NADH dehydrogenase
CHR48_00621	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CHR48_00622	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CHR48_00623	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CHR48_00625	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CHR48_00626	COG0195	Participates in both transcription termination and antitermination
CHR48_00627	COG0779	Required for maturation of 30S ribosomal subunits
CHR48_00630	COG1304	FMN binding
CHR48_00637	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CHR48_00638	COG0738	Major facilitator superfamily
CHR48_00640	COG0287	Prephenate dehydrogenase
CHR48_00641	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CHR48_00642	COG4684	Psort location CytoplasmicMembrane, score
CHR48_00643	COG1621	beta-fructofuranosidase activity
CHR48_00645	COG0384	phenazine biosynthesis protein PhzF
CHR48_00656	COG1846	Transcriptional regulator
CHR48_00658	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CHR48_00659	COG0656	L-ascorbic acid biosynthetic process
CHR48_00661	COG0583	DNA-binding transcription factor activity
CHR48_00668	COG0488	(ABC) transporter
CHR48_00673	COG2814	Major facilitator Superfamily
CHR48_00674	COG2239	Acts as a magnesium transporter
CHR48_00675	COG0564	pseudouridine synthase activity
CHR48_00676	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CHR48_00677	COG2357	RelA SpoT domain protein
CHR48_00680	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CHR48_00681	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CHR48_00698	COG1940	carbohydrate kinase activity
CHR48_00700	COG1028	Short-chain dehydrogenase reductase Sdr
CHR48_00705	COG0352	thiamine-phosphate diphosphorylase activity
CHR48_00706	COG0351	phosphomethylpyrimidine kinase
CHR48_00707	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CHR48_00710	COG1464	Belongs to the NlpA lipoprotein family
CHR48_00713	COG0436	Aminotransferase
CHR48_00714	COG0277	FAD linked oxidase domain protein
CHR48_00719	COG2801	Transposase and inactivated derivatives
CHR48_00728	COG2801	Transposase and inactivated derivatives
CHR48_00732	COG0604	alcohol dehydrogenase
CHR48_00732	COG3321	synthase
CHR48_00734	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CHR48_00744	COG3201	nicotinamide mononucleotide transporter
CHR48_00745	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CHR48_00749	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CHR48_00752	COG1473	amidohydrolase
CHR48_00754	COG3527	Alpha-acetolactate decarboxylase
CHR48_00755	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CHR48_00756	COG0187	DNA topoisomerase II activity
CHR48_00757	COG3118	belongs to the thioredoxin family
CHR48_00761	COG1193	negative regulation of DNA recombination
CHR48_00765	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CHR48_00766	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CHR48_00767	COG0544	peptidyl-prolyl cis-trans isomerase activity
CHR48_00772	COG0268	Binds directly to 16S ribosomal RNA
CHR48_00773	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CHR48_00774	COG1466	dna polymerase III delta subunit
CHR48_00775	COG0658	competence protein
CHR48_00775	COG2333	competence protein COMEC
CHR48_00777	COG3906	Belongs to the UPF0473 family
CHR48_00781	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CHR48_00782	COG1929	Belongs to the glycerate kinase type-1 family
CHR48_00784	COG0513	Belongs to the DEAD box helicase family
CHR48_00785	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CHR48_00786	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CHR48_00787	COG1862	Preprotein translocase
CHR48_00788	COG0343	queuine tRNA-ribosyltransferase activity
CHR48_00795	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CHR48_00796	COG2255	four-way junction helicase activity
CHR48_00797	COG0632	four-way junction helicase activity
CHR48_00800	COG0516	GMP reductase activity
CHR48_00800	COG0517	IMP dehydrogenase activity
CHR48_00804	COG1739	Uncharacterized protein family UPF0029
CHR48_00805	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CHR48_00806	COG0322	excinuclease ABC activity
CHR48_00809	COG1668	transmembrane transport
CHR48_00810	COG4152	abc transporter atp-binding protein
CHR48_00812	COG1674	ftsk spoiiie
CHR48_00814	COG0628	permease
CHR48_00815	COG2706	6-phosphogluconolactonase activity
CHR48_00819	COG0751	glycine-tRNA ligase activity
CHR48_00820	COG0752	glycyl-tRNA synthetase alpha subunit
CHR48_00823	COG1381	Involved in DNA repair and RecF pathway recombination
CHR48_00824	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CHR48_00825	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CHR48_00826	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CHR48_00827	COG1702	phosphate starvation-inducible protein PhoH
CHR48_00828	COG1610	YqeY-like protein
CHR48_00829	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CHR48_00830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CHR48_00832	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CHR48_00833	COG0124	histidyl-tRNA synthetase
CHR48_00834	COG0860	N-Acetylmuramoyl-L-alanine amidase
CHR48_00837	COG3425	synthase
CHR48_00838	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CHR48_00852	COG0006	proline dipeptidase activity
CHR48_00853	COG1609	Transcriptional regulator
CHR48_00856	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CHR48_00857	COG1164	Oligoendopeptidase f
CHR48_00859	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CHR48_00860	COG2723	6-phospho-beta-galactosidase activity
CHR48_00861	COG1447	Phosphotransferase system cellobiose-specific component IIA
CHR48_00862	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CHR48_00863	COG2723	6-phospho-beta-galactosidase activity
CHR48_00864	COG4862	establishment of competence for transformation
CHR48_00865	COG1393	Belongs to the ArsC family
CHR48_00866	COG3853	Toxic anion resistance protein (TelA)
CHR48_00879	COG0561	phosphatase activity
CHR48_00880	COG1970	mechanosensitive ion channel activity
CHR48_00881	COG1428	Deoxynucleoside kinase
CHR48_00883	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CHR48_00884	COG1942	4-Oxalocrotonate Tautomerase
CHR48_00885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CHR48_00887	COG0335	large ribosomal subunit rRNA binding
CHR48_00888	COG0336	Belongs to the RNA methyltransferase TrmD family
CHR48_00889	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CHR48_00890	COG0588	phosphoglycerate mutase activity
CHR48_00894	COG0228	four-way junction DNA binding
CHR48_00898	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CHR48_00900	COG0552	protein localization to endoplasmic reticulum
CHR48_00901	COG1196	nuclear chromosome segregation
CHR48_00902	COG0571	ribonuclease III activity
CHR48_00903	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHR48_00904	COG0416	fatty acid biosynthetic process
CHR48_00905	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CHR48_00907	COG0438	transferase activity, transferring glycosyl groups
CHR48_00910	COG1461	Dihydroxyacetone kinase
CHR48_00912	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CHR48_00914	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CHR48_00915	COG1162	GTPase activity
CHR48_00916	COG2815	serine threonine protein kinase
CHR48_00916	COG0515	serine threonine protein kinase
CHR48_00917	COG0631	protein serine/threonine phosphatase activity
CHR48_00918	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CHR48_00918	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CHR48_00919	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CHR48_00920	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CHR48_00921	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CHR48_00929	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CHR48_00930	COG2252	PERMEase
CHR48_00931	COG0217	transcriptional regulatory protein
CHR48_00932	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CHR48_00936	COG3599	regulation of cell shape
CHR48_00939	COG1799	cell septum assembly
CHR48_00941	COG0849	cell division
CHR48_00942	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CHR48_00943	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CHR48_00944	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CHR48_00945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CHR48_00948	COG0275	rRNA processing
CHR48_00949	COG2001	Belongs to the MraZ family
CHR48_00951	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CHR48_00952	COG2264	protein methyltransferase activity
CHR48_00954	COG0833	amino acid
CHR48_00957	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHR48_00960	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CHR48_00961	COG0151	Belongs to the GarS family
CHR48_00962	COG0138	bifunctional purine biosynthesis protein purh
CHR48_00963	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CHR48_00964	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CHR48_00966	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CHR48_00969	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CHR48_00970	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CHR48_00971	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CHR48_00974	COG1126	abc transporter atp-binding protein
CHR48_00975	COG0765	amino acid transport
CHR48_00977	COG3338	carbonate dehydratase activity
CHR48_00978	COG1792	Involved in formation and maintenance of cell shape
CHR48_00979	COG1077	Cell shape determining protein MreB Mrl
CHR48_00980	COG2003	Belongs to the UPF0758 family
CHR48_00983	COG1263	PTS System
CHR48_00983	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHR48_00983	COG2190	(PTS) system
CHR48_00984	COG1307	EDD domain protein, DegV family
CHR48_00985	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CHR48_00986	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CHR48_00987	COG0038	chloride channel
CHR48_00989	COG4120	Belongs to the binding-protein-dependent transport system permease family
CHR48_00991	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHR48_00992	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHR48_00993	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CHR48_00997	COG0741	lytic transglycosylase activity
CHR48_00999	COG0400	carboxylic ester hydrolase activity
CHR48_01000	COG0346	lactoylglutathione lyase activity
CHR48_01001	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CHR48_01003	COG0494	nUDIX hydrolase
CHR48_01007	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CHR48_01008	COG1388	LysM domain
CHR48_01008	COG1705	Flagellar rod assembly protein muramidase FlgJ
CHR48_01009	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CHR48_01010	COG4988	ABC transporter
CHR48_01011	COG1294	oxidase, subunit
CHR48_01012	COG1271	oxidase subunit
CHR48_01013	COG4684	Psort location CytoplasmicMembrane, score
CHR48_01037	COG1098	S1 RNA binding domain
CHR48_01038	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CHR48_01039	COG0586	Pfam SNARE associated Golgi protein
CHR48_01041	COG0194	GDP metabolic process
CHR48_01043	COG0497	DNA recombination
CHR48_01044	COG1438	arginine binding
CHR48_01045	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CHR48_01046	COG0142	geranyltranstransferase activity
CHR48_01048	COG1570	exodeoxyribonuclease VII activity
CHR48_01049	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CHR48_01050	COG4720	Psort location CytoplasmicMembrane, score
CHR48_01053	COG1136	(ABC) transporter
CHR48_01054	COG0577	efflux transmembrane transporter activity
CHR48_01056	COG0776	regulation of translation
CHR48_01057	COG0363	glucosamine-6-phosphate deaminase activity
CHR48_01059	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CHR48_01079	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CHR48_01080	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CHR48_01082	COG1323	Belongs to the UPF0348 family
CHR48_01083	COG2226	methyltransferase
CHR48_01084	COG0799	negative regulation of ribosome biogenesis
CHR48_01085	COG1713	HD superfamily hydrolase involved in NAD metabolism
CHR48_01086	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CHR48_01088	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CHR48_01089	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CHR48_01090	COG1181	Belongs to the D-alanine--D-alanine ligase family
CHR48_01092	COG0531	amino acid
CHR48_01093	COG0459	protein refolding
CHR48_01094	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CHR48_01095	COG0488	(ABC) transporter
CHR48_01099	COG0285	dihydrofolate synthase activity
CHR48_01101	COG0525	valine-tRNA ligase activity
CHR48_01108	COG1272	protein, Hemolysin III
CHR48_01130	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CHR48_01132	COG5506	Protein of unknown function (DUF1694)
CHR48_01134	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CHR48_01139	COG2137	regulation of response to DNA damage stimulus
CHR48_01140	COG0704	Plays a role in the regulation of phosphate uptake
CHR48_01141	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CHR48_01142	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CHR48_01143	COG0581	inorganic phosphate transmembrane transporter activity
CHR48_01144	COG0573	inorganic phosphate transmembrane transporter activity
CHR48_01145	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CHR48_01149	COG0673	inositol 2-dehydrogenase activity
CHR48_01150	COG4166	transmembrane transport
CHR48_01151	COG0647	UMP catabolic process
CHR48_01152	COG4470	Protein conserved in bacteria
CHR48_01153	COG0737	Belongs to the 5'-nucleotidase family
CHR48_01157	COG4948	Mandelate Racemase Muconate Lactonizing
CHR48_01158	COG0596	Alpha beta hydrolase
CHR48_01159	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CHR48_01162	COG0778	Nitroreductase
CHR48_01163	COG1132	(ABC) transporter
CHR48_01165	COG1472	Belongs to the glycosyl hydrolase 3 family
CHR48_01166	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CHR48_01167	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CHR48_01172	COG0174	glutamine synthetase
CHR48_01173	COG0789	Transcriptional regulator
CHR48_01174	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CHR48_01175	COG0584	glycerophosphoryl diester phosphodiesterase
CHR48_01179	COG3942	CHAP domain
CHR48_01180	COG5632	N-Acetylmuramoyl-L-alanine amidase
CHR48_01180	COG3409	Peptidoglycan-binding domain 1 protein
CHR48_01181	COG1940	carbohydrate kinase activity
CHR48_01184	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CHR48_01185	COG0768	penicillin binding
CHR48_01187	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CHR48_01188	COG0514	ATP-dependent DNA helicase (RecQ)
CHR48_01189	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CHR48_01190	COG0072	phenylalanine-tRNA ligase activity
CHR48_01190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHR48_01191	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CHR48_01192	COG1733	regulation of RNA biosynthetic process
CHR48_01194	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHR48_01198	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CHR48_01199	COG0653	protein targeting
CHR48_01201	COG4956	integral membrane protein (PIN domain superfamily)
CHR48_01203	COG0756	dUTP diphosphatase activity
CHR48_01205	COG0791	NLP P60 protein
CHR48_01206	COG1388	LysM domain
CHR48_01206	COG3942	CHAP domain
CHR48_01208	COG3527	Alpha-acetolactate decarboxylase
CHR48_01209	COG0028	Belongs to the TPP enzyme family
CHR48_01210	COG0039	L-malate dehydrogenase activity
CHR48_01214	COG1914	H( )-stimulated, divalent metal cation uptake system
CHR48_01216	COG1263	PTS System
CHR48_01216	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHR48_01219	COG0740	serine-type endopeptidase activity
CHR48_01220	COG1481	regulation of sporulation
CHR48_01221	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CHR48_01222	COG1660	Displays ATPase and GTPase activities
CHR48_01224	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CHR48_01225	COG2814	Major facilitator Superfamily
CHR48_01227	COG0671	phosphoesterase, PA-phosphatase related
CHR48_01233	COG1573	uracil-dna glycosylase
CHR48_01236	COG0028	Belongs to the TPP enzyme family
CHR48_01239	COG4221	oxidoreductase activity
CHR48_01241	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CHR48_01242	COG0101	tRNA pseudouridine synthase activity
CHR48_01244	COG1122	ATPase activity
CHR48_01245	COG1122	ATPase activity
CHR48_01247	COG1252	NADH dehydrogenase
CHR48_01248	COG0803	Belongs to the bacterial solute-binding protein 9 family
CHR48_01249	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHR48_01250	COG1121	(ABC) transporter
CHR48_01252	COG0222	ribosome binding
CHR48_01253	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CHR48_01254	COG0081	regulation of translation
CHR48_01255	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CHR48_01256	COG0250	Participates in transcription elongation, termination and antitermination
CHR48_01257	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CHR48_01260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHR48_01261	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CHR48_01262	COG1854	S-ribosylhomocysteine lyase activity
CHR48_01263	COG1464	Belongs to the NlpA lipoprotein family
CHR48_01264	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CHR48_01265	COG0626	cystathionine gamma-synthase activity
CHR48_01266	COG0215	cysteine-tRNA ligase activity
CHR48_01267	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CHR48_01268	COG0039	L-malate dehydrogenase activity
CHR48_01269	COG0471	metal ion transport
CHR48_01270	COG1053	succinate dehydrogenase
CHR48_01271	COG0114	fumarate hydratase activity
CHR48_01272	COG0583	DNA-binding transcription factor activity
CHR48_01277	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CHR48_01280	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CHR48_01285	COG0203	ribosomal protein L17
CHR48_01286	COG0202	RNA polymerase activity
CHR48_01287	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CHR48_01289	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CHR48_01290	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CHR48_01293	COG0200	Binds to the 23S rRNA
CHR48_01294	COG1841	ribosomal large subunit assembly
CHR48_01295	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CHR48_01296	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CHR48_01297	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CHR48_01298	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CHR48_01299	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CHR48_01300	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CHR48_01301	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CHR48_01303	COG0255	Belongs to the universal ribosomal protein uL29 family
CHR48_01304	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CHR48_01305	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CHR48_01306	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CHR48_01307	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CHR48_01308	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CHR48_01309	COG0089	rRNA binding
CHR48_01311	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CHR48_01312	COG0051	transcription antitermination factor activity, RNA binding
CHR48_01313	COG0142	geranyltranstransferase activity
CHR48_01314	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CHR48_01316	COG0456	acetyltransferase
CHR48_01317	COG1214	PFAM Peptidase M22, glycoprotease
CHR48_01318	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CHR48_01322	COG3870	Protein conserved in bacteria
CHR48_01323	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CHR48_01328	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CHR48_01329	COG0590	tRNA wobble adenosine to inosine editing
CHR48_01330	COG2813	Specifically methylates the guanine in position
CHR48_01332	COG2807	transmembrane transport
CHR48_01334	COG3620	sequence-specific DNA binding
CHR48_01343	COG0500	methyltransferase
CHR48_01344	COG1309	transcriptional regulator
CHR48_01348	COG1979	alcohol dehydrogenase
CHR48_01352	COG0085	RNA polymerase activity
CHR48_01353	COG0542	response to heat
CHR48_01354	COG4463	regulation of RNA biosynthetic process
CHR48_01359	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CHR48_01360	COG1428	Deoxynucleoside kinase
CHR48_01361	COG1876	peptidase activity
CHR48_01362	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CHR48_01363	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CHR48_01364	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CHR48_01365	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CHR48_01366	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CHR48_01367	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CHR48_01368	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CHR48_01369	COG0356	it plays a direct role in the translocation of protons across the membrane
CHR48_01370	COG2233	PERMEase
CHR48_01372	COG0702	epimerase
CHR48_01373	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CHR48_01374	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CHR48_01375	COG0009	L-threonylcarbamoyladenylate synthase
CHR48_01376	COG2890	protein-(glutamine-N5) methyltransferase activity
CHR48_01377	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CHR48_01378	COG1435	thymidine kinase activity
CHR48_01380	COG3442	glutamine amidotransferase
CHR48_01381	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CHR48_01382	COG1482	cell wall glycoprotein biosynthetic process
CHR48_01384	COG0110	maltose O-acetyltransferase activity
CHR48_01389	COG1132	(ABC) transporter
CHR48_01390	COG1132	(ABC) transporter
CHR48_01394	COG0588	phosphoglycerate mutase activity
CHR48_01398	COG0708	Exodeoxyribonuclease III
CHR48_01400	COG1454	alcohol dehydrogenase
CHR48_01400	COG1012	belongs to the aldehyde dehydrogenase family
CHR48_01401	COG3590	peptidase
CHR48_01409	COG5039	Polysaccharide pyruvyl transferase
CHR48_01412	COG2801	Transposase and inactivated derivatives
CHR48_01413	COG1215	transferase activity, transferring glycosyl groups
CHR48_01414	COG1216	Glycosyl transferase, family 2
CHR48_01414	COG1442	glycosyl transferase family 8
CHR48_01418	COG0463	Glycosyl transferase, family 2
CHR48_01418	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CHR48_01421	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CHR48_01422	COG2188	Transcriptional regulator
CHR48_01423	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CHR48_01424	COG2814	Major facilitator Superfamily
CHR48_01425	COG1418	mRNA catabolic process
CHR48_01428	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CHR48_01429	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CHR48_01430	COG1215	transferase activity, transferring glycosyl groups
CHR48_01438	COG0765	amino acid transport
CHR48_01445	COG0656	L-ascorbic acid biosynthetic process
CHR48_01446	COG2160	L-arabinose isomerase activity
CHR48_01451	COG3940	Belongs to the glycosyl hydrolase 43 family
CHR48_01454	COG0534	Mate efflux family protein
CHR48_01455	COG0488	(ABC) transporter
CHR48_01456	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CHR48_01457	COG1121	(ABC) transporter
CHR48_01459	COG1846	Transcriptional regulator
CHR48_01462	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CHR48_01462	COG2755	lipolytic protein G-D-S-L family
CHR48_01463	COG3091	SprT-like family
CHR48_01472	COG4975	Glucose uptake
CHR48_01473	COG0477	Major facilitator Superfamily
CHR48_01474	COG3104	oligopeptide transport
CHR48_01484	COG1686	Belongs to the peptidase S11 family
CHR48_01486	COG0745	RESPONSE REGULATOR receiver
CHR48_01488	COG0012	GTP binding
CHR48_01489	COG4481	Protein conserved in bacteria
CHR48_01490	COG1475	DNA binding
CHR48_01491	COG1192	Involved in chromosome partitioning
CHR48_01492	COG0357	Ribosomal RNA small subunit methyltransferase G
CHR48_01494	COG1194	a g-specific adenine glycosylase
CHR48_01495	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CHR48_01503	COG5002	protein histidine kinase activity
CHR48_01504	COG0745	RESPONSE REGULATOR receiver
CHR48_01507	COG0318	PFAM AMP-dependent synthetase and ligase
CHR48_01508	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CHR48_01509	COG2050	protein possibly involved in aromatic compounds catabolism
CHR48_01510	COG1335	isochorismatase
CHR48_01511	COG2226	methyltransferase
CHR48_01513	COG4443	Transcriptional Coactivator p15 (PC4)
CHR48_01514	COG0252	asparaginase activity
CHR48_01515	COG0531	amino acid
CHR48_01516	COG1113	amino acid transport
CHR48_01517	COG0531	amino acid
CHR48_01519	COG4975	Glucose uptake
CHR48_01520	COG0477	Major facilitator Superfamily
CHR48_01523	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CHR48_01525	COG2267	carboxylic ester hydrolase activity
CHR48_01526	COG4166	transmembrane transport
CHR48_01527	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CHR48_01529	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CHR48_01531	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CHR48_01533	COG3223	Belongs to the PsiE family
CHR48_01535	COG0531	amino acid
CHR48_01536	COG1228	amidohydrolase
CHR48_01539	COG2070	2-Nitropropane dioxygenase
CHR48_01541	COG0583	DNA-binding transcription factor activity
CHR48_01542	COG2855	membrane
CHR48_01544	COG3620	sequence-specific DNA binding
CHR48_01545	COG2855	membrane
CHR48_01548	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CHR48_01553	COG1113	amino acid transport
CHR48_01559	COG0628	permease
CHR48_01561	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CHR48_01561	COG0392	lysyltransferase activity
CHR48_01564	COG1254	Belongs to the acylphosphatase family
CHR48_01565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR48_01566	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR48_01568	COG0765	amino acid transport
CHR48_01569	COG1126	abc transporter atp-binding protein
CHR48_01571	COG1131	(ABC) transporter
CHR48_01573	COG0390	transport system, permease component
CHR48_01574	COG4619	ABC transporter
CHR48_01576	COG0656	L-ascorbic acid biosynthetic process
CHR48_01578	COG1132	(ABC) transporter
CHR48_01579	COG1846	Transcriptional regulator
CHR48_01583	COG1744	ABC transporter substrate-binding protein PnrA-like
CHR48_01584	COG0697	spore germination
CHR48_01586	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CHR48_01589	COG0789	Transcriptional regulator
CHR48_01594	COG1131	(ABC) transporter
CHR48_01598	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CHR48_01599	COG0505	Belongs to the CarA family
CHR48_01600	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CHR48_01601	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CHR48_01603	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CHR48_01604	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CHR48_01605	COG0165	Argininosuccinate lyase
CHR48_01606	COG0137	argininosuccinate synthase activity
CHR48_01607	COG1744	ABC transporter substrate-binding protein PnrA-like
CHR48_01610	COG0697	spore germination
CHR48_01614	COG2723	6-phospho-beta-galactosidase activity
CHR48_01615	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CHR48_01615	COG0517	IMP dehydrogenase activity
CHR48_01620	COG1476	TRANSCRIPTIONal
CHR48_01634	COG1881	PFAM PEBP family protein
CHR48_01642	COG2252	PERMEase
CHR48_01643	COG3152	Membrane
CHR48_01647	COG0328	RNA-DNA hybrid ribonuclease activity
CHR48_01649	COG0561	phosphatase activity
CHR48_01650	COG2409	Drug exporters of the RND superfamily
CHR48_01650	COG1033	growth of symbiont in host cell
CHR48_01651	COG0577	efflux transmembrane transporter activity
CHR48_01652	COG1136	(ABC) transporter
CHR48_01654	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CHR48_01655	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CHR48_01657	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHR48_01659	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHR48_01663	COG1113	amino acid transport
CHR48_01664	COG0569	domain protein
CHR48_01667	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CHR48_01669	COG1120	ATPase activity
CHR48_01671	COG0706	membrane insertase activity
CHR48_01672	COG0594	ribonuclease P activity
CHR48_01673	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CHR48_01674	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CHR48_01675	COG0592	DNA-directed DNA polymerase activity
CHR48_01676	COG2501	S4 domain
CHR48_01677	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CHR48_01678	COG0187	DNA topoisomerase II activity
CHR48_01681	COG2153	protein acetylation
CHR48_01682	COG1368	sulfuric ester hydrolase activity
CHR48_01686	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CHR48_01699	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHR48_01699	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHR48_01701	COG0084	hydrolase, TatD family'
CHR48_01702	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CHR48_01703	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CHR48_01704	COG1253	flavin adenine dinucleotide binding
CHR48_01705	COG1253	flavin adenine dinucleotide binding
CHR48_01706	COG4466	Protein conserved in bacteria
CHR48_01707	COG2131	deaminase
CHR48_01708	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CHR48_01709	COG1316	TRANSCRIPTIONal
CHR48_01710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHR48_01710	COG1263	PTS System
CHR48_01711	COG2723	6-phospho-beta-galactosidase activity
CHR48_01712	COG2723	6-phospho-beta-galactosidase activity
CHR48_01714	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CHR48_01717	COG0737	Belongs to the 5'-nucleotidase family
CHR48_01718	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CHR48_01719	COG1983	PspC domain protein
CHR48_01720	COG1695	Transcriptional regulator
CHR48_01723	COG1968	undecaprenyl-diphosphatase activity
CHR48_01724	COG2818	Glycosylase
CHR48_01729	COG3507	Belongs to the glycosyl hydrolase 43 family
CHR48_01730	COG2211	Major facilitator Superfamily
CHR48_01732	COG2115	Belongs to the xylose isomerase family
CHR48_01734	COG0667	Aldo Keto reductase
CHR48_01737	COG0477	Major facilitator Superfamily
CHR48_01738	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CHR48_01741	COG1309	transcriptional regulator
CHR48_01742	COG1511	domain protein
CHR48_01742	COG1511	domain protein
CHR48_01744	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CHR48_01746	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CHR48_01747	COG0297	glycogen (starch) synthase activity
CHR48_01748	COG0058	SHG alpha-glucan phosphorylase activity
CHR48_01750	COG0193	aminoacyl-tRNA hydrolase activity
CHR48_01751	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CHR48_01752	COG2244	polysaccharide biosynthetic process
CHR48_01753	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CHR48_01755	COG0037	tRNA processing
CHR48_01758	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CHR48_01759	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CHR48_01772	COG2261	transglycosylase associated protein
CHR48_01773	COG0656	L-ascorbic acid biosynthetic process
CHR48_01775	COG1737	Transcriptional regulator
CHR48_01776	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CHR48_01786	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CHR48_01789	COG1216	Glycosyl transferase, family 2
CHR48_01792	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CHR48_01793	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CHR48_01794	COG1447	Phosphotransferase system cellobiose-specific component IIA
CHR48_01795	COG2723	6-phospho-beta-galactosidase activity
CHR48_01796	COG2723	6-phospho-beta-galactosidase activity
CHR48_01797	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CHR48_01799	COG0436	Aminotransferase
CHR48_01803	COG2190	(PTS) system
CHR48_01803	COG2211	Major facilitator Superfamily
CHR48_01804	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CHR48_01805	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CHR48_01806	COG0444	Belongs to the ABC transporter superfamily
CHR48_01807	COG4608	Belongs to the ABC transporter superfamily
CHR48_01808	COG0601	transmembrane transport
CHR48_01809	COG0601	transmembrane transport
CHR48_01810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR48_01811	COG0747	negative chemotaxis
CHR48_01812	COG1132	(ABC) transporter
CHR48_01813	COG1132	(ABC) transporter
CHR48_01814	COG1132	(ABC) transporter
CHR48_01817	COG1956	GAF domain-containing protein
CHR48_01820	COG2233	PERMEase
CHR48_01821	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CHR48_01822	COG4989	oxidoreductase activity
CHR48_01823	COG1620	l-lactate permease
CHR48_01825	COG1028	Short-chain dehydrogenase reductase Sdr
CHR48_01826	COG2084	Dehydrogenase
CHR48_01832	COG0438	transferase activity, transferring glycosyl groups
CHR48_01854	COG3842	ATPase activity
CHR48_01855	COG1175	transmembrane transport
CHR48_01856	COG0395	ABC-type sugar transport system, permease component
CHR48_01859	COG0542	response to heat
CHR48_01860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR48_01861	COG2040	homocysteine
CHR48_01862	COG0833	amino acid
CHR48_01863	COG0308	aminopeptidase N
CHR48_01867	COG2207	Transcriptional regulator
CHR48_01870	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CHR48_01871	COG0745	RESPONSE REGULATOR receiver
CHR48_01872	COG2205	protein histidine kinase activity
CHR48_01874	COG1316	TRANSCRIPTIONal
CHR48_01876	COG0024	Methionine aminopeptidase
CHR48_01878	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CHR48_01880	COG2801	Transposase and inactivated derivatives
CHR48_01882	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CHR48_01886	COG2723	6-phospho-beta-galactosidase activity
CHR48_01891	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CHR48_01893	COG0671	phosphoesterase, PA-phosphatase related
CHR48_01894	COG0495	leucyl-tRNA aminoacylation
CHR48_01895	COG0438	transferase activity, transferring glycosyl groups
CHR48_01897	COG2244	polysaccharide biosynthetic process
CHR48_01901	COG0626	cystathionine gamma-synthase activity
CHR48_01902	COG1902	pentaerythritol trinitrate reductase activity
CHR48_01904	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CHR48_01906	COG0531	amino acid
CHR48_01907	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHR48_01910	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CHR48_01913	COG1064	alcohol dehydrogenase
CHR48_01914	COG2814	Major facilitator Superfamily
CHR48_01917	COG1051	belongs to the nudix hydrolase family
CHR48_01918	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CHR48_01920	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CHR48_01923	COG0360	Binds together with S18 to 16S ribosomal RNA
CHR48_01924	COG0629	single-stranded DNA binding
CHR48_01925	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CHR48_01931	COG0745	RESPONSE REGULATOR receiver
CHR48_01935	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CHR48_01936	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CHR48_01938	COG1078	dGTPase activity
CHR48_01939	COG0561	phosphatase activity
CHR48_01940	COG3343	RNA polymerase activity
CHR48_01942	COG0504	CTP synthase activity
CHR48_01943	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CHR48_01946	COG2337	Toxic component of a toxin-antitoxin (TA) module
CHR48_01950	COG1696	Membrane protein involved in D-alanine export
CHR48_01952	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CHR48_01956	COG3973	AAA domain
CHR48_01959	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CHR48_01960	COG2211	Major facilitator Superfamily
CHR48_01965	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CHR48_01965	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CHR48_01966	COG1268	BioY protein
CHR48_01967	COG0194	GDP metabolic process
CHR48_01970	COG1126	abc transporter atp-binding protein
CHR48_01971	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CHR48_01972	COG0765	amino acid transport
CHR48_01973	COG0765	amino acid transport
CHR48_01974	COG4166	transmembrane transport
CHR48_01975	COG0601	transmembrane transport
CHR48_01976	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHR48_01977	COG0444	Belongs to the ABC transporter superfamily
CHR48_01978	COG4608	Belongs to the ABC transporter superfamily
CHR48_01980	COG0359	binds to the 23S rRNA
CHR48_01981	COG0305	Participates in initiation and elongation during chromosome replication
CHR48_01982	COG2814	Major facilitator Superfamily
CHR48_01984	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CHR48_01989	COG2832	Protein of unknown function (DUF454)
CHR48_01992	COG1744	ABC transporter substrate-binding protein PnrA-like
CHR48_01995	COG0492	ferredoxin-NADP+ reductase activity
CHR48_01998	COG0588	phosphoglycerate mutase activity
CHR48_01999	COG0386	Belongs to the glutathione peroxidase family
CHR48_02003	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CHR48_02004	COG0628	permease
CHR48_02005	COG0640	Transcriptional regulator
CHR48_02007	COG0446	pyridine nucleotide-disulphide oxidoreductase
CHR48_02012	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CHR48_02013	COG1077	Cell shape determining protein MreB Mrl
CHR48_02015	COG0772	Belongs to the SEDS family
CHR48_02016	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CHR48_02020	COG0561	phosphatase activity
CHR48_02021	COG2169	Transcriptional regulator
CHR48_02021	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CHR48_02022	COG0561	phosphatase activity
CHR48_02024	COG0577	efflux transmembrane transporter activity
CHR48_02024	COG1136	(ABC) transporter
CHR48_02029	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CHR48_02030	COG2814	Major facilitator Superfamily
CHR48_02032	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CHR48_02033	COG0352	thiamine-phosphate diphosphorylase activity
CHR48_02035	COG2252	PERMEase
CHR48_02037	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CHR48_02047	COG0604	alcohol dehydrogenase
CHR48_02048	COG4166	transmembrane transport
CHR48_02049	COG1228	amidohydrolase
CHR48_02052	COG2814	Major facilitator Superfamily
CHR48_02053	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CHR48_02054	COG0656	L-ascorbic acid biosynthetic process
CHR48_02055	COG1307	EDD domain protein, DegV family
CHR48_02058	COG1435	thymidine kinase activity
CHR48_02060	COG2076	Multidrug Resistance protein
CHR48_02061	COG2076	Multidrug Resistance protein
CHR48_02064	COG0307	riboflavin synthase, alpha
CHR48_02065	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHR48_02065	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CHR48_02066	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CHR48_02068	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CHR48_02070	COG1174	glycine betaine transport
CHR48_02072	COG1979	alcohol dehydrogenase
CHR48_02073	COG1811	Na channel or pump
CHR48_02078	COG2246	polysaccharide biosynthetic process
CHR48_02079	COG0561	phosphatase activity
CHR48_02080	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CHR48_02081	COG4589	Belongs to the CDS family
CHR48_02082	COG0750	zinc metalloprotease
CHR48_02083	COG0442	prolyl-tRNA aminoacylation
CHR48_02084	COG2176	DNA-directed DNA polymerase activity
CHR48_02085	COG2176	DNA-directed DNA polymerase activity
CHR48_02100	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CHR48_02101	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CHR48_02102	COG1040	competence protein
CHR48_02103	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CHR48_02106	COG2183	response to ionizing radiation
CHR48_02111	COG1940	carbohydrate kinase activity
CHR48_02112	COG2723	6-phospho-beta-galactosidase activity
CHR48_02113	COG3711	transcriptional antiterminator
CHR48_02117	COG1309	transcriptional regulator
CHR48_02121	COG2217	Heavy metal translocating P-type atpase
CHR48_02122	COG2814	Major facilitator Superfamily
CHR48_02131	COG0438	transferase activity, transferring glycosyl groups
CHR48_02141	COG2217	Heavy metal translocating P-type atpase
CHR48_02143	COG2235	arginine
CHR48_02144	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CHR48_02149	COG3759	membrane
CHR48_02150	COG1136	(ABC) transporter
CHR48_02151	COG0577	efflux transmembrane transporter activity
CHR48_02157	COG1609	Transcriptional regulator
CHR48_02160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CHR48_02163	COG0246	Mannitol dehydrogenase
CHR48_02164	COG1312	Catalyzes the dehydration of D-mannonate
CHR48_02165	COG1904	glucuronate isomerase
CHR48_02166	COG0800	Aldolase
CHR48_02167	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHR48_02169	COG1464	Belongs to the NlpA lipoprotein family
CHR48_02170	COG1506	peptidase
CHR48_02170	COG0823	Involved in the tonB-independent uptake of proteins
CHR48_02170	COG4946	Tricorn protease homolog
CHR48_02173	COG0561	phosphatase activity
CHR48_02183	COG0302	gtp cyclohydrolase
CHR48_02183	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CHR48_02184	COG0302	gtp cyclohydrolase
CHR48_02185	COG0285	dihydrofolate synthase activity
CHR48_02187	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CHR48_02188	COG1116	anion transmembrane transporter activity
CHR48_02190	COG0318	PFAM AMP-dependent synthetase and ligase
CHR48_02192	COG2223	nitrite transmembrane transporter activity
CHR48_02197	COG1609	Transcriptional regulator
CHR48_02200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CHR48_02204	COG1609	Transcriptional regulator
CHR48_02205	COG1869	D-ribose catabolic process
CHR48_02206	COG0738	Major facilitator superfamily
CHR48_02213	COG0494	nUDIX hydrolase
CHR48_02216	COG2801	Transposase and inactivated derivatives
CHR48_02230	COG0516	GMP reductase activity