locus-tag	class	description
AUC63_00010	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AUC63_00011	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AUC63_00012	ENOG4105DZP	Membrane-associated zinc metalloprotease
AUC63_00013	ENOG4105KNE	Phosphatidate cytidylyltransferase
AUC63_00014	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AUC63_00015	ENOG4108HCJ	Hydrolase
AUC63_00016	ENOG4105WH5	Teichoic acid glycosylation protein
AUC63_00021	ENOG4108UQV	Membrane
AUC63_00022	ENOG4107QW4	alcohol dehydrogenase
AUC63_00024	ENOG4105E90	ABC transporter
AUC63_00026	ENOG4105E0X	reductase
AUC63_00028	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AUC63_00029	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AUC63_00030	ENOG4108R6K	riboflavin synthase, subunit alpha
AUC63_00032	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AUC63_00033	ENOG41080TC	multidrug resistance protein
AUC63_00034	ENOG4105KPY	Small multidrug resistance protein
AUC63_00036	ENOG4107104	thymidine kinase
AUC63_00039	ENOG4108RCR	degv family
AUC63_00041	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AUC63_00042	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AUC63_00045	ENOG4105CI2	imidazolone-5-propionate hydrolase
AUC63_00046	ENOG4108J59	Extracellular solute-binding protein, family 5
AUC63_00047	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
AUC63_00056	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AUC63_00059	ENOG4105C7N	Xanthine uracil vitamin C permease
AUC63_00061	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AUC63_00062	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
AUC63_00064	ENOG4105F27	Major Facilitator
AUC63_00065	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AUC63_00067	ENOG4105FDP	GntR family transcriptional regulator
AUC63_00068	ENOG4105CE4	GlcNAc 6-P deacetylase
AUC63_00069	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AUC63_00071	ENOG4108HCJ	Hydrolase
AUC63_00072	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AUC63_00073	ENOG4105DQF	Hydrolase
AUC63_00077	ENOG4105II7	pyrroline-5-carboxylate reductase
AUC63_00080	ENOG4105DFF	Rod shape-determining protein mreb
AUC63_00081	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
AUC63_00083	ENOG4105UIB	(ABC) transporter
AUC63_00084	ENOG4108JQ9	ABC transporter
AUC63_00085	ENOG4105DIH	basic membrane
AUC63_00086	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AUC63_00088	ENOG41080HT	Transcriptional regulator, arsr family
AUC63_00089	ENOG4106F5Q	Membrane
AUC63_00091	ENOG4105F0I	Aminotransferase
AUC63_00094	ENOG4108V06	Glutathione peroxidase
AUC63_00095	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AUC63_00098	ENOG4105CAY	ferredoxin--nadp reductase
AUC63_00101	ENOG4105DIH	basic membrane
AUC63_00102	ENOG4105DIH	basic membrane
AUC63_00103	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AUC63_00104	ENOG4105WD1	Membrane
AUC63_00109	ENOG4107PP3	Acetylornithine deacetylase
AUC63_00111	ENOG410605W	Major Facilitator
AUC63_00112	ENOG4105CDU	Replicative dna helicase
AUC63_00113	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AUC63_00115	ENOG4108JQ7	(ABC) transporter
AUC63_00117	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AUC63_00118	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AUC63_00119	ENOG4108J59	Extracellular solute-binding protein, family 5
AUC63_00120	ENOG4105DRP	amino acid AbC transporter
AUC63_00121	ENOG4105EAD	ABC transporter
AUC63_00122	ENOG4105CT1	(ABC) transporter
AUC63_00123	ENOG4105CDA	abc transporter atp-binding protein
AUC63_00126	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AUC63_00127	ENOG4105VKD	bioY protein
AUC63_00128	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AUC63_00133	ENOG4105CT4	transporter
AUC63_00134	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AUC63_00137	ENOG4105EEM	helicase
AUC63_00141	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
AUC63_00143	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
AUC63_00147	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
AUC63_00148	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AUC63_00149	ENOG4105C1J	atp-dependent rna helicase
AUC63_00150	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AUC63_00151	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AUC63_00153	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
AUC63_00154	ENOG410667J	hydrolase
AUC63_00155	ENOG4105DCI	Phosphohydrolase
AUC63_00157	ENOG4105C0H	protease
AUC63_00158	ENOG4105Q2H	domain protein
AUC63_00162	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AUC63_00169	ENOG4108UUM	single-stranded DNA-binding protein
AUC63_00170	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AUC63_00172	ENOG4105DU0	nucleoside hydrolase
AUC63_00173	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AUC63_00175	ENOG4105DFT	pur operon repressor
AUC63_00176	ENOG4108Z4K	mutator MutT protein
AUC63_00179	ENOG410605W	Major Facilitator
AUC63_00181	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
AUC63_00182	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AUC63_00185	ENOG4107QSE	Dipeptidase
AUC63_00186	ENOG4107R7I	amino acid
AUC63_00188	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
AUC63_00190	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AUC63_00191	ENOG4105C28	cystathionine
AUC63_00197	ENOG4105CG5	Glycosyl transferase (Group 1
AUC63_00198	ENOG4105C8T	Leucyl-tRNA synthetase
AUC63_00199	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AUC63_00201	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AUC63_00206	ENOG4105CS2	ec 3.2.1.21
AUC63_00212	ENOG4105DQ6	Transposase
AUC63_00218	ENOG4108KGH	TRANSCRIPTIONal
AUC63_00221	ENOG4108STX	response regulator
AUC63_00222	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AUC63_00225	ENOG41075H3	AraC family transcriptional regulator
AUC63_00229	ENOG4105CD8	aminopeptidase N
AUC63_00230	ENOG4108IQI	permease
AUC63_00231	ENOG4107QK5	Homocysteine s-methyltransferase
AUC63_00233	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AUC63_00236	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
AUC63_00237	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
AUC63_00238	ENOG4108IJ9	(ABC) transporter
AUC63_00241	ENOG4105DC8	reductase
AUC63_00266	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AUC63_00267	ENOG4105CHR	reductase
AUC63_00269	ENOG4105DAA	L-lactate
AUC63_00270	ENOG4107RGM	aldo keto reductase
AUC63_00271	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
AUC63_00272	ENOG4105C2W	permease
AUC63_00274	ENOG4105DC8	reductase
AUC63_00275	ENOG4108ZGC	gaf domain protein
AUC63_00278	ENOG4105BZ1	(ABC) transporter
AUC63_00279	ENOG4105BZ1	(ABC) transporter
AUC63_00280	ENOG4105BZ1	(ABC) transporter
AUC63_00281	ENOG4105HJK	ABC transporter
AUC63_00282	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AUC63_00283	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AUC63_00284	ENOG4108JQ7	(ABC) transporter
AUC63_00285	ENOG4105C3U	ABC transporter
AUC63_00286	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
AUC63_00287	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
AUC63_00288	ENOG4107RBJ	symporter
AUC63_00292	ENOG4105CHM	Aminotransferase
AUC63_00294	ENOG4105CK1	PTS System
AUC63_00295	ENOG4105CS2	ec 3.2.1.21
AUC63_00296	ENOG4105CS2	ec 3.2.1.21
AUC63_00297	ENOG4105VCP	PTS System
AUC63_00298	ENOG4105VZJ	PTS System
AUC63_00299	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AUC63_00302	ENOG4107S6X	Glycosyl transferase, family 2
AUC63_00315	ENOG4106KNT	transcriptional regulator
AUC63_00318	ENOG4107BMA	Transglycosylase associated protein
AUC63_00331	ENOG4105CRK	lysyL-tRNA synthetase
AUC63_00332	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AUC63_00335	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AUC63_00337	ENOG41082I2	s4 domain protein
AUC63_00339	ENOG4108JA2	transcriptioN-repair coupling factor
AUC63_00340	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AUC63_00343	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AUC63_00344	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AUC63_00345	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AUC63_00346	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AUC63_00348	ENOG4105ECB	domain protein
AUC63_00348	ENOG4105ECB	domain protein
AUC63_00352	ENOG4105CK1	PTS System
AUC63_00353	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AUC63_00356	ENOG4105CPC	Aldo Keto reductase
AUC63_00357	ENOG4105CMG	Carbohydrate kinase
AUC63_00358	ENOG4105C93	Xylose Isomerase
AUC63_00360	ENOG4105CT4	transporter
AUC63_00361	ENOG4105DSG	hydrolase family 43
AUC63_00362	ENOG4107QNK	)-transporter
AUC63_00366	ENOG4108R3E	Dna-3-methyladenine glycosylase i
AUC63_00367	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AUC63_00371	ENOG41067S9	phage shock protein C, PspC
AUC63_00373	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
AUC63_00376	ENOG4105D5T	phosphonate abc transporter
AUC63_00378	ENOG4105CS2	ec 3.2.1.21
AUC63_00379	ENOG4105CS2	ec 3.2.1.21
AUC63_00380	ENOG4105C5Y	PTS System
AUC63_00381	ENOG4108KGH	TRANSCRIPTIONal
AUC63_00382	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AUC63_00383	ENOG4108UK2	deaminase
AUC63_00384	ENOG4105W42	Veg protein
AUC63_00385	ENOG4105C37	(CBS) domain
AUC63_00386	ENOG4105C37	(CBS) domain
AUC63_00388	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
AUC63_00389	ENOG4105F8V	Hydrolase, tatD family
AUC63_00390	ENOG4105EEQ	Na H antiporter
AUC63_00391	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AUC63_00404	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AUC63_00408	ENOG4105E0M	Sulfatase
AUC63_00411	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AUC63_00412	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AUC63_00413	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AUC63_00414	ENOG410848D	S4 domain protein YaaA
AUC63_00415	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AUC63_00416	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AUC63_00417	ENOG4105VG0	50S ribosomal protein l34
AUC63_00418	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AUC63_00419	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AUC63_00420	ENOG4105C3F	Signal peptidase i
AUC63_00421	ENOG4105E0A	ABC, transporter
AUC63_00423	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
AUC63_00426	ENOG4107ZYR	domain protein
AUC63_00427	ENOG4105C85	amino acid
AUC63_00431	ENOG4107QN2	dihydrolipoyl dehydrogenase
AUC63_00433	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AUC63_00438	ENOG4105C19	ABC transporter
AUC63_00439	ENOG4107RBB	ABC transporter, permease
AUC63_00440	ENOG4105EYF	MMPL domain protein
AUC63_00441	ENOG4105DQF	Hydrolase
AUC63_00443	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AUC63_00447	ENOG4105KAF	membrAne
AUC63_00448	ENOG4105C7N	Xanthine uracil vitamin C permease
AUC63_00450	ENOG4105CP7	Triose-phosphate isomerase
AUC63_00456	ENOG4105KIS	phospholipid-binding protein
AUC63_00470	ENOG4105VZ8	Transcriptional regulator
AUC63_00475	ENOG4105C2X	Arabinose 5-phosphate isomerase
AUC63_00476	ENOG4105CS2	ec 3.2.1.21
AUC63_00482	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AUC63_00483	ENOG4105DIH	basic membrane
AUC63_00484	ENOG4105CDH	Citrulline--aspartate ligase
AUC63_00485	ENOG4105CH7	arginosuccinase
AUC63_00486	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AUC63_00487	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AUC63_00489	ENOG4105C8Y	Acetylornithine aminotransferase
AUC63_00490	ENOG4105DBV	ornithine carbamoyltransferase
AUC63_00491	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AUC63_00492	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AUC63_00496	ENOG4105CIG	ABC transporter
AUC63_00501	ENOG4105VUF	Transcriptional regulator
AUC63_00502	ENOG4105CHR	reductase
AUC63_00504	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AUC63_00506	ENOG4108UZ3	Transporter
AUC63_00507	ENOG4105DIH	basic membrane
AUC63_00511	ENOG41067TZ	transcriptional regulator, MarR family
AUC63_00512	ENOG4105BZ1	(ABC) transporter
AUC63_00516	ENOG41083J0	(ABC) transporter
AUC63_00517	ENOG4105C4B	ABC transporter, permease
AUC63_00519	ENOG4105CZV	ABC transporter
AUC63_00521	ENOG4105CDA	abc transporter atp-binding protein
AUC63_00522	ENOG4105E5Q	amino acid AbC transporter
AUC63_00525	ENOG4105EAB	amino acid AbC transporter
AUC63_00526	ENOG410855V	Acylphosphatase
AUC63_00530	ENOG4105C02	permease
AUC63_00531	ENOG4105KVH	Transcriptional regulator
AUC63_00536	ENOG4105C85	amino acid
AUC63_00544	ENOG4105HMI	Membrane
AUC63_00545	ENOG41067QW	Transcriptional regulator
AUC63_00547	ENOG4105HMI	Membrane
AUC63_00548	ENOG4108KB2	LysR family Transcriptional regulator
AUC63_00549	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
AUC63_00550	ENOG4105EA8	2-Nitropropane dioxygenase
AUC63_00553	ENOG4105CI2	imidazolone-5-propionate hydrolase
AUC63_00554	ENOG4105CUB	amino acid
AUC63_00556	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
AUC63_00558	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AUC63_00560	ENOG4107U9W	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX (By similarity)
AUC63_00562	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AUC63_00563	ENOG4108J59	Extracellular solute-binding protein, family 5
AUC63_00564	ENOG4107T66	Releases the N-terminal proline from various substrates (By similarity)
AUC63_00566	ENOG4108W5N	phosphatidylglycerophosphatase a
AUC63_00569	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AUC63_00572	ENOG4107R7I	amino acid
AUC63_00574	ENOG4105CUB	amino acid
AUC63_00575	ENOG4105HDK	L-asparaginase
AUC63_00576	ENOG4105VEM	Conserved domain protein
AUC63_00578	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AUC63_00580	ENOG4105KA0	thioesterase Superfamily protein
AUC63_00581	ENOG4108IPT	Naphthoate synthase
AUC63_00582	ENOG4105CEY	Amp-dependent synthetase and ligase
AUC63_00585	ENOG4108STX	response regulator
AUC63_00586	ENOG4105US7	Histidine kinase
AUC63_00594	ENOG4105E66	phosphoriboisomerase A
AUC63_00595	ENOG4105CEN	a g-specific adenine glycosylase
AUC63_00598	ENOG4107QJE	Chromosome Partitioning Protein
AUC63_00599	ENOG4105FA0	parb-like partition protein
AUC63_00600	ENOG4105VDK	protein, conserved in bacteria
AUC63_00601	ENOG4105C3G	gtp-binding protein
AUC63_00603	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AUC63_00615	ENOG4105DUX	Transporter
AUC63_00617	ENOG4105CSC	Glucose uptake protein
AUC63_00618	ENOG4105EVU	fructokinase
AUC63_00619	ENOG4107QNK	)-transporter
AUC63_00626	ENOG410906U	SprT-like
AUC63_00627	ENOG4105EXC	Acyl-transferase
AUC63_00630	ENOG41067TZ	transcriptional regulator, MarR family
AUC63_00632	ENOG4105FDK	ABC transporter
AUC63_00633	ENOG4105FAV	ABC, transporter
AUC63_00634	ENOG4105C5H	ABC transporter
AUC63_00635	ENOG4107R73	Mate efflux family protein
AUC63_00638	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
AUC63_00643	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
AUC63_00644	ENOG4105CV8	reductase
AUC63_00649	ENOG4107QNK	)-transporter
AUC63_00651	ENOG4105EAD	ABC transporter
AUC63_00659	ENOG4107R8N	Glycosyl transferase, family 2
AUC63_00660	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
AUC63_00661	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
AUC63_00666	ENOG4105D3Q	Sugar transferase
AUC63_00667	ENOG4108TZY	GntR Family Transcriptional Regulator
AUC63_00668	ENOG4107QRI	Phosphoketolase
AUC63_00671	ENOG4107SJB	teichoic acid biosynthesis
AUC63_00674	ENOG4108RYC	glycosyltransferase
AUC63_00677	ENOG4105DQ6	Transposase
AUC63_00688	ENOG4105C9K	Endothelin-converting enzyme 1
AUC63_00689	ENOG4108EKI	Dehydrogenase
AUC63_00691	ENOG4105CGK	Exodeoxyribonuclease III
AUC63_00695	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AUC63_00696	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AUC63_00699	ENOG4105BZ1	(ABC) transporter
AUC63_00700	ENOG4105BZ1	(ABC) transporter
AUC63_00705	ENOG4108UW5	maltose o-acetyltransferase
AUC63_00707	ENOG4105DG6	mannose-6-phosphate isomerase
AUC63_00708	ENOG4105DMS	mur ligase
AUC63_00709	ENOG4105F1K	Glutamine amidotransferase
AUC63_00711	ENOG4107104	thymidine kinase
AUC63_00712	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AUC63_00713	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AUC63_00714	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AUC63_00715	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AUC63_00716	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AUC63_00717	ENOG4105CGD	Nad-dependent epimerase dehydratase
AUC63_00720	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
AUC63_00721	ENOG4105WS6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AUC63_00722	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
AUC63_00723	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AUC63_00724	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AUC63_00725	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AUC63_00726	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AUC63_00727	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AUC63_00728	ENOG4108VXD	carboxy-peptidase
AUC63_00729	ENOG4105ZMH	deoxynucleoside kinase
AUC63_00730	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AUC63_00735	ENOG4105KEX	transcriptional regulator, ctsr
AUC63_00737	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AUC63_00738	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AUC63_00741	ENOG4107QW4	alcohol dehydrogenase
AUC63_00745	ENOG4107Z3H	Transcriptional regulator, TetR family
AUC63_00746	ENOG4105DHI	Methyltransferase
AUC63_00755	ENOG41067QW	Transcriptional regulator
AUC63_00757	ENOG4105DJ2	Major Facilitator Superfamily
AUC63_00758	ENOG4108URH	decarboxylase
AUC63_00759	ENOG4107Y49	methyltransferase
AUC63_00760	ENOG4108Z6B	deaminase
AUC63_00761	ENOG4105C6E	dna polymerase iii
AUC63_00763	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AUC63_00766	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AUC63_00767	ENOG4105X0R	protein from nitrogen regulatory protein P-II
AUC63_00771	ENOG4105CMR	udp-glucose 4-epimerase
AUC63_00772	ENOG41072GX	Peptidase M22 Glycoprotease
AUC63_00773	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
AUC63_00777	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AUC63_00778	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AUC63_00779	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AUC63_00780	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AUC63_00781	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AUC63_00783	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AUC63_00784	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AUC63_00786	ENOG41082SA	50s ribosomal protein l29
AUC63_00787	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AUC63_00788	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AUC63_00789	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AUC63_00790	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AUC63_00791	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AUC63_00792	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AUC63_00794	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AUC63_00796	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AUC63_00797	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AUC63_00799	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AUC63_00800	ENOG41067V7	50S ribosomal protein L36
AUC63_00801	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AUC63_00802	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AUC63_00803	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AUC63_00804	ENOG4108ZT0	50S ribosomal protein l17
AUC63_00808	ENOG4108UMI	ABC transporter, permease
AUC63_00809	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AUC63_00810	ENOG4105D01	(LipO)protein
AUC63_00812	ENOG4105DAP	Nicotinate phosphoribosyltransferase
AUC63_00813	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
AUC63_00817	ENOG4107RSM	transcriptional regulator
AUC63_00818	ENOG4105C9Q	fumarate hydratase class II
AUC63_00819	ENOG4107EFR	Flavocytochrome c
AUC63_00820	ENOG4107QPK	)-transporter
AUC63_00821	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AUC63_00822	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
AUC63_00823	ENOG4105C8N	cysteinyl-tRNA synthetase
AUC63_00824	ENOG4105C28	cystathionine
AUC63_00826	ENOG4105D01	(LipO)protein
AUC63_00827	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
AUC63_00828	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AUC63_00829	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AUC63_00831	ENOG4107FTN	50S ribosomal protein L33
AUC63_00832	ENOG410683Z	Preprotein translocase SecE subunit
AUC63_00833	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AUC63_00834	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AUC63_00835	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AUC63_00836	ENOG4108VZM	50s ribosomal protein L10
AUC63_00837	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AUC63_00839	ENOG4105DIK	(ABC) transporter
AUC63_00840	ENOG4105CC5	ABC transporter
AUC63_00841	ENOG4105DSE	periplasmic solute binding protein
AUC63_00844	ENOG4108JJB	ABC transporter
AUC63_00845	ENOG4108JJB	ABC transporter
AUC63_00847	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AUC63_00848	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AUC63_00849	ENOG4108UJD	30S ribosomal protein S9
AUC63_00850	ENOG4105EMU	Dehydrogenase
AUC63_00853	ENOG4105C7K	acetolactate synthase
AUC63_00856	ENOG4108RG0	uracil-dna glycosylase
AUC63_00859	ENOG4105CG3	alpha amylase, catalytic region
AUC63_00862	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AUC63_00864	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AUC63_00865	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AUC63_00868	ENOG4105CHW	UPF0052 protein
AUC63_00869	ENOG4105CIE	May be required for sporulation (By similarity)
AUC63_00870	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AUC63_00873	ENOG4105C5Y	PTS System
AUC63_00874	ENOG41086FC	50S ribosomal protein l32
AUC63_00875	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
AUC63_00879	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AUC63_00881	ENOG4107FQX	Alpha-acetolactate decarboxylase
AUC63_00883	ENOG41068JE	domain protein
AUC63_00884	ENOG4105K4H	Nlp p60 protein
AUC63_00886	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AUC63_00888	ENOG4105CTP	PilT protein domain protein
AUC63_00889	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AUC63_00890	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AUC63_00891	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AUC63_00895	ENOG4108RWN	rrna methyltransferase
AUC63_00898	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AUC63_00899	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AUC63_00901	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AUC63_00902	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AUC63_00904	ENOG4107RF6	penicillin-binding protein
AUC63_00905	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AUC63_00909	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
AUC63_00910	ENOG41068JE	domain protein
AUC63_00914	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
AUC63_00915	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AUC63_00916	ENOG4105KV4	Transcriptional regulator
AUC63_00917	ENOG4105C5F	glutamine synthetase
AUC63_00923	ENOG4105K46	50S ribosomal protein l27
AUC63_00926	ENOG4105BZ1	(ABC) transporter
AUC63_00927	ENOG4108DBC	nitroreductase
AUC63_00928	ENOG4105E4F	Isochorismate synthase
AUC63_00929	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
AUC63_00930	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
AUC63_00931	ENOG4105DTQ	mandelate racemase muconate lactonizing
AUC63_00935	ENOG4107R8B	5'-nucleotidase
AUC63_00936	ENOG4105MMD	transcriptional regulator
AUC63_00937	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
AUC63_00938	ENOG4108J59	Extracellular solute-binding protein, family 5
AUC63_00939	ENOG4105D9R	oxidoreductase
AUC63_00943	ENOG4105CVA	phosphate
AUC63_00944	ENOG4105C8U	phosphate abc transporter
AUC63_00945	ENOG4105E2Z	phosphate ABC transporter (Permease
AUC63_00946	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AUC63_00947	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AUC63_00948	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AUC63_00949	ENOG410902V	Modulates RecA activity (By similarity)
AUC63_00954	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AUC63_00958	ENOG4105D1H	recombination factor protein RarA
AUC63_00980	ENOG4108UT2	hemolysin iii
AUC63_00987	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AUC63_00989	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AUC63_00990	ENOG4107XU6	Glycosyl transferase (Group 1
AUC63_00993	ENOG4105C5H	ABC transporter
AUC63_00994	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AUC63_00995	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AUC63_00996	ENOG4105C0X	amino acid
AUC63_00999	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
AUC63_01000	ENOG4105CQW	ribosome biogenesis GTPase YqeH
AUC63_01002	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AUC63_01003	ENOG4108WF2	Metal Dependent Phosphohydrolase
AUC63_01005	ENOG4105DXX	methyltransferase
AUC63_01006	ENOG4105CDE	UPF0348 protein
AUC63_01008	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AUC63_01009	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AUC63_01029	ENOG4105C22	threonyL-tRNA synthetase
AUC63_01031	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
AUC63_01032	ENOG4105K70	DNA-binding protein
AUC63_01034	ENOG4107WD8	ABC transporter, permease
AUC63_01038	ENOG4108V7D	UPF0397 protein
AUC63_01039	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AUC63_01040	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AUC63_01041	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AUC63_01042	ENOG4105CTB	Polyprenyl synthetase
AUC63_01043	ENOG4105DX0	Hemolysin A
AUC63_01044	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
AUC63_01045	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AUC63_01047	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AUC63_01048	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AUC63_01049	ENOG4105DQR	SNARE associated Golgi
AUC63_01050	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AUC63_01075	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AUC63_01076	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AUC63_01077	ENOG4108JJ9	ABC, transporter
AUC63_01078	ENOG4108JJ8	(ABC) transporter
AUC63_01080	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
AUC63_01084	ENOG4108YZ4	nudix hydrolase
AUC63_01086	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
AUC63_01088	ENOG4105FBA	Phospholipase Carboxylesterase
AUC63_01094	ENOG41067VN	Glutaredoxin
AUC63_01095	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AUC63_01096	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AUC63_01098	ENOG4105C7J	ABC transporter, permease
AUC63_01099	ENOG4108JJB	ABC transporter
AUC63_01100	ENOG4105CMQ	Chloride channel
AUC63_01101	ENOG41087RV	Protein CrcB homolog
AUC63_01102	ENOG4106A8V	Protein CrcB homolog
AUC63_01103	ENOG4105EPR	degv family
AUC63_01104	ENOG4105CI1	PTS System
AUC63_01107	ENOG4105W5Q	DNA repair protein (RadC
AUC63_01108	ENOG4105DFF	Rod shape-determining protein mreb
AUC63_01109	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AUC63_01110	ENOG4108UHE	carbonic anhydrase
AUC63_01112	ENOG4105E5Q	amino acid AbC transporter
AUC63_01113	ENOG4105CDA	abc transporter atp-binding protein
AUC63_01114	ENOG4108HW3	(ABC) transporter
AUC63_01115	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AUC63_01116	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AUC63_01117	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AUC63_01118	ENOG4105C8V	SAICAR synthetase
AUC63_01120	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
AUC63_01121	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
AUC63_01123	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AUC63_01124	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AUC63_01125	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AUC63_01126	ENOG4105C12	Phosphoribosylglycinamide synthetase
AUC63_01127	ENOG4105CKU	formyltetrahydrofolate synthetase
AUC63_01130	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AUC63_01133	ENOG4108IQI	permease
AUC63_01134	ENOG4105CA9	Pyruvate kinase
AUC63_01135	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AUC63_01136	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AUC63_01138	ENOG4108V6E	Cell division protein mraZ
AUC63_01141	ENOG4105CJN	penicillin-binding protein
AUC63_01142	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AUC63_01143	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AUC63_01144	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AUC63_01145	ENOG41087KY	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
AUC63_01146	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AUC63_01148	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
AUC63_01155	ENOG4105C7H	Helicase, RecD TraA family
AUC63_01156	ENOG4105CDY	transcriptional regulatory protein
AUC63_01157	ENOG4105C7N	Xanthine uracil vitamin C permease
AUC63_01166	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AUC63_01167	ENOG4105C25	Primosomal protein n'
AUC63_01168	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AUC63_01169	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AUC63_01170	ENOG4108ZF3	Phosphatase
AUC63_01171	ENOG4105D9P	serine threonine protein kinase
AUC63_01172	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AUC63_01173	ENOG4105DJV	ribulose-phosphate 3-epimerase
AUC63_01175	ENOG4105VB9	50S ribosomal protein l28
AUC63_01177	ENOG4105DP4	dak2 domain fusion protein ylov
AUC63_01180	ENOG4105E2K	Glycosyl transferase (Group 1
AUC63_01182	ENOG4105CB5	ATP-dependent DNA helicase recG
AUC63_01183	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AUC63_01184	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AUC63_01185	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AUC63_01186	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AUC63_01187	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AUC63_01189	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AUC63_01193	ENOG4105K5M	30s ribosomal protein S16
AUC63_01194	ENOG4105DU1	integral membrane protein, terc
AUC63_01197	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AUC63_01198	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AUC63_01199	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AUC63_01200	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AUC63_01202	ENOG4107AYK	membrAne
AUC63_01203	ENOG41069HH	4-oxalocrotonate tautomerase
AUC63_01206	ENOG4105ZMH	deoxynucleoside kinase
AUC63_01207	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AUC63_01208	ENOG410667J	hydrolase
AUC63_01221	ENOG4105CDW	Resistance protein
AUC63_01222	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
AUC63_01223	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
AUC63_01224	ENOG4105CS2	ec 3.2.1.21
AUC63_01225	ENOG4105VZJ	PTS System
AUC63_01226	ENOG4105VCP	PTS System
AUC63_01227	ENOG4105CS2	ec 3.2.1.21
AUC63_01228	ENOG4105CK1	PTS System
AUC63_01230	ENOG4105DPN	Oligoendopeptidase f
AUC63_01231	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AUC63_01234	ENOG4105ETE	Transcriptional regulator (LacI family
AUC63_01235	ENOG4105DC7	peptidase M24
AUC63_01249	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AUC63_01250	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
AUC63_01253	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AUC63_01254	ENOG4105CUT	histidyl-tRNA synthetase
AUC63_01255	ENOG4105C9M	aspartyl-trna synthetase
AUC63_01257	ENOG4107AYK	membrAne
AUC63_01258	ENOG4105VCC	30S ribosomal protein S21
AUC63_01259	ENOG4105KTH	gatB Yqey
AUC63_01260	ENOG4105C9A	Phoh family
AUC63_01261	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AUC63_01263	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AUC63_01267	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
AUC63_01268	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AUC63_01270	ENOG4105DU1	integral membrane protein, terc
AUC63_01272	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
AUC63_01274	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AUC63_01275	ENOG4105CNU	cell division protein FtsK
AUC63_01277	ENOG4108IUX	(ABC) transporter
AUC63_01278	ENOG4105RHA	ABC transporter, permease
AUC63_01281	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AUC63_01282	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AUC63_01283	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AUC63_01286	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AUC63_01287	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AUC63_01288	ENOG4105CPN	adenine deaminase
AUC63_01289	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AUC63_01290	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AUC63_01291	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AUC63_01298	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AUC63_01299	ENOG4105VIE	preprotein translocase, subunit YajC
AUC63_01300	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AUC63_01301	ENOG4105SFS	phosphoesterase RecJ domain protein
AUC63_01302	ENOG4105C1J	atp-dependent rna helicase
AUC63_01304	ENOG4105BZW	Glycerate kinase
AUC63_01305	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AUC63_01306	ENOG4105VBH	UPF0297 protein
AUC63_01307	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AUC63_01308	ENOG4105VPH	UPF0473 protein
AUC63_01309	ENOG4105VPH	UPF0473 protein
AUC63_01311	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
AUC63_01312	ENOG4105TQK	DNA polymerase iii, delta' subunit
AUC63_01313	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AUC63_01314	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AUC63_01317	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AUC63_01321	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AUC63_01325	ENOG4105C98	muts2 protein
AUC63_01329	ENOG4105K63	Thioredoxin
AUC63_01330	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AUC63_01331	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AUC63_01332	ENOG4107FQX	Alpha-acetolactate decarboxylase
AUC63_01337	ENOG4107QUV	Domain protein
AUC63_01341	ENOG4107DB1	DUF218 domain
AUC63_01350	ENOG4105CQB	FAD linked oxidase domain protein
AUC63_01351	ENOG4105CQB	FAD linked oxidase domain protein
AUC63_01352	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AUC63_01353	ENOG4105C9X	ppx gppa phosphatase
AUC63_01354	ENOG4108JA1	polyketide synthase
AUC63_01358	ENOG4105DQ6	Transposase
AUC63_01367	ENOG4105DQ6	Transposase
AUC63_01372	ENOG4105CQB	FAD linked oxidase domain protein
AUC63_01373	ENOG4105CHM	Aminotransferase
AUC63_01375	ENOG4105D01	(LipO)protein
AUC63_01376	ENOG4105D01	(LipO)protein
AUC63_01379	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
AUC63_01380	ENOG4105DWF	phosphomethylpyrimidine kinase
AUC63_01381	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AUC63_01388	ENOG4105EVU	fructokinase
AUC63_01405	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AUC63_01406	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AUC63_01410	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AUC63_01411	ENOG4105EMS	pseudouridine synthase
AUC63_01412	ENOG4105CJW	magnesium transporter
AUC63_01413	ENOG4105C2C	drug resistance transporter, Bcr CflA
AUC63_01418	ENOG4105C5H	ABC transporter
AUC63_01425	ENOG4106NZI	LysR family Transcriptional regulator
AUC63_01428	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
AUC63_01430	ENOG4108U05	Transcriptional regulator
AUC63_01434	ENOG4105PGM	cation diffusion facilitator family transporter
AUC63_01441	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AUC63_01442	ENOG4105C5Y	PTS System
AUC63_01444	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AUC63_01445	ENOG4105EVN	Prephenate dehydrogenase
AUC63_01447	ENOG4105EMV	Major Facilitator
AUC63_01448	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AUC63_01458	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AUC63_01459	ENOG4105CHV	Transcription elongation factor NusA
AUC63_01460	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
AUC63_01462	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AUC63_01463	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AUC63_01464	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AUC63_01465	ENOG4105CEP	NADH dehydrogenase
AUC63_01467	ENOG4105DTN	riboflavin biosynthesis protein ribF
AUC63_01468	ENOG4105F23	Fibronectin-binding protein
AUC63_01469	ENOG4106N3A	copper homeostasis protein cutc
AUC63_01472	ENOG4105DEU	major facilitator superfamily
AUC63_01473	ENOG4105EPR	degv family
AUC63_01474	ENOG4108RCR	degv family
AUC63_01475	ENOG41090WU	lipolytic protein G-D-S-L family
AUC63_01477	ENOG4105VSD	UPF0346 protein
AUC63_01478	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
AUC63_01479	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AUC63_01480	ENOG4105C79	DNA protecting protein DprA
AUC63_01481	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AUC63_01482	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AUC63_01484	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
AUC63_01485	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
AUC63_01488	ENOG4108IJ7	Glycine betaine
AUC63_01491	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AUC63_01492	ENOG4105D01	(LipO)protein
AUC63_01493	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AUC63_01503	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AUC63_01504	ENOG4105WBI	UPF0223 protein
AUC63_01505	ENOG4105ECY	inositol monophosphatase
AUC63_01506	ENOG4105CI3	gtp-binding protein typa
AUC63_01507	ENOG4105CNI	cell division protein FtsW
AUC63_01508	ENOG4105WUC	UPF0298 protein
AUC63_01509	ENOG4106H78	methyltransferase
AUC63_01510	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AUC63_01511	ENOG41063PX	domain protein
AUC63_01512	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AUC63_01514	ENOG4108VA3	3-hexulose-6-phosphate synthase
AUC63_01515	ENOG41080HJ	6-phospho 3-hexuloisomerase
AUC63_01516	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AUC63_01517	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AUC63_01523	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AUC63_01524	ENOG4105BZU	Histidine kinase
AUC63_01525	ENOG4105DBI	uridine monophosphokinase
AUC63_01526	ENOG4105CN9	Peptidase m42 family protein
AUC63_01527	ENOG4108VDD	TRNA binding domain protein
AUC63_01529	ENOG4105DFU	Cell wall formation (By similarity)
AUC63_01530	ENOG4105HFZ	Membrane
AUC63_01531	ENOG4105C2M	dna polymerase I
AUC63_01532	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AUC63_01533	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AUC63_01538	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AUC63_01539	ENOG4105GR3	Histidine kinase
AUC63_01541	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
AUC63_01543	ENOG4107SC7	Inner membrane transporter yjeM
AUC63_01546	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
AUC63_01547	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
AUC63_01548	ENOG4108JYZ	YitT family
AUC63_01550	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
AUC63_01554	ENOG4105DVT	helicase
AUC63_01556	ENOG4105C5S	asparaginyl-tRNA synthetase
AUC63_01559	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
AUC63_01560	ENOG4108UKS	UPF0398 protein
AUC63_01561	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
AUC63_01563	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AUC63_01564	ENOG4105C4R	Atp-dependent dna helicase
AUC63_01565	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AUC63_01569	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AUC63_01571	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AUC63_01572	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AUC63_01574	ENOG4105DUX	Transporter
AUC63_01575	ENOG4107VKM	6-phosphogluconolactonase
AUC63_01577	ENOG4105K59	histidine triad (HIT) protein
AUC63_01580	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AUC63_01582	ENOG41065RQ	ADP-ribosylation crystallin J1
AUC63_01587	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AUC63_01588	ENOG4105GP2	5'(3')-deoxyribonucleotidase
AUC63_01589	ENOG4105E98	transcriptional regulator DeoR family
AUC63_01590	ENOG4105DE4	1-phosphofructokinase
AUC63_01591	ENOG4105DM4	PTS System
AUC63_01595	ENOG4105CJ3	phosphate transporter
AUC63_01597	ENOG4108XXK	NUDIX hydrolase
AUC63_01599	ENOG4105CS2	ec 3.2.1.21
AUC63_01603	ENOG4107R7I	amino acid
AUC63_01605	ENOG4106KNP	GTP-binding protein LepA C-terminus
AUC63_01606	ENOG4107QNK	)-transporter
AUC63_01608	ENOG4105IKJ	beta-galactosidase small subunit
AUC63_01612	ENOG410807C	QueT transporter
AUC63_01614	ENOG4107QTZ	amino acid
AUC63_01615	ENOG4105EMU	Dehydrogenase
AUC63_01616	ENOG4107ZGM	malolactic fermentation system
AUC63_01617	ENOG4105C6K	Malic enzyme
AUC63_01619	ENOG4105DC8	reductase
AUC63_01623	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AUC63_01624	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
AUC63_01628	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AUC63_01633	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AUC63_01635	ENOG4105EGD	dinuclear metal center protein, YbgI family
AUC63_01637	ENOG4106943	Heat shock protein
AUC63_01638	ENOG41068YB	TPR repeat-containing protein
AUC63_01647	ENOG4105EYH	Exonuclease
AUC63_01648	ENOG4107RFY	SbcCD D subunit
AUC63_01650	ENOG4105DJ2	Major Facilitator Superfamily
AUC63_01651	ENOG4105PUK	Membrane
AUC63_01652	ENOG4105DWF	phosphomethylpyrimidine kinase
AUC63_01654	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AUC63_01655	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AUC63_01656	ENOG4105CAT	Cytidine monophosphate kinase
AUC63_01658	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AUC63_01660	ENOG4108SAX	Membrane
AUC63_01663	ENOG4105FE9	pseudouridine synthase
AUC63_01664	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AUC63_01665	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AUC63_01668	ENOG4105QNR	S1 RNA binding domain protein
AUC63_01670	ENOG4107RWR	Sodium hydrogen exchanger
AUC63_01672	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AUC63_01673	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AUC63_01674	ENOG4105C0B	DNA polymerase III (alpha subunit)
AUC63_01676	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
AUC63_01677	ENOG4105C5H	ABC transporter
AUC63_01678	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AUC63_01683	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AUC63_01685	ENOG4105BZU	Histidine kinase
AUC63_01688	ENOG4108KGH	TRANSCRIPTIONal
AUC63_01691	ENOG4105K64	Glycosyl transferase, family 2
AUC63_01694	ENOG4107QRS	glycosyltransferase group 2 family protein
AUC63_01696	ENOG4108PQP	glycosyl transferase group 1
AUC63_01697	ENOG4105D3Q	Sugar transferase
AUC63_01698	ENOG4107YJ4	chain length determinant protein
AUC63_01701	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AUC63_01702	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AUC63_01703	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AUC63_01704	ENOG4105CE9	30S ribosomal protein S2
AUC63_01705	ENOG4105VC4	domain protein
AUC63_01706	ENOG41060K3	Methyltransferase
AUC63_01707	ENOG4105F6E	Acyl-transferase
AUC63_01708	ENOG4105Z8B	NlpC/P60 family
AUC63_01711	ENOG4105VXM	UPF0154 protein
AUC63_01712	ENOG4105VPS	UPF0291 protein
AUC63_01713	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AUC63_01716	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AUC63_01717	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AUC63_01721	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AUC63_01722	ENOG4105CFG	Acts as a chaperone (By similarity)
AUC63_01723	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AUC63_01724	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AUC63_01730	ENOG4108RJ9	Glycosyl transferase, family 2
AUC63_01732	ENOG4105CKK	Glycosyl transferase, family 2
AUC63_01734	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
AUC63_01737	ENOG4105D5D	udp-galactopyranose mutase
AUC63_01741	ENOG4105D3Q	Sugar transferase
AUC63_01742	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AUC63_01747	ENOG4105DQ6	Transposase
AUC63_01757	ENOG4105C88	aminopeptidase
AUC63_01760	ENOG4108YBP	pseudouridine synthase
AUC63_01765	ENOG4105CS9	pantothenic acid kinase
AUC63_01766	ENOG4105EEM	helicase
AUC63_01768	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AUC63_01769	ENOG4105CEV	competence damage-inducible protein
AUC63_01770	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AUC63_01776	ENOG4105C7K	acetolactate synthase
AUC63_01778	ENOG4105CMG	Carbohydrate kinase
AUC63_01780	ENOG4106D4I	domain protein
AUC63_01783	ENOG4105WZB	UPF0342 protein
AUC63_01784	ENOG4105BZ4	penicillin-binding protein
AUC63_01785	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
AUC63_01790	ENOG41062ES	Transcriptional regulator
AUC63_01794	ENOG4105C75	arginyL-tRNA synthetase
AUC63_01796	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AUC63_01797	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AUC63_01799	ENOG4105DIK	(ABC) transporter
AUC63_01800	ENOG4105CC5	ABC transporter
AUC63_01801	ENOG4108XAN	ABC transporter
AUC63_01803	ENOG4105CBD	Diacylglycerol kinase
AUC63_01804	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AUC63_01805	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AUC63_01806	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AUC63_01807	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AUC63_01808	ENOG4108KP7	hydrolase
AUC63_01809	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
AUC63_01812	ENOG4105K7K	Transcriptional regulator
AUC63_01814	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
AUC63_01818	ENOG4105CPC	Aldo Keto reductase
AUC63_01819	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AUC63_01820	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
AUC63_01821	ENOG4108JJB	ABC transporter
AUC63_01824	ENOG4105C79	DNA protecting protein DprA
AUC63_01827	ENOG4105FF2	Type I DHQase
AUC63_01828	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AUC63_01829	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AUC63_01830	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AUC63_01831	ENOG4105D49	3-dehydroquinate synthase
AUC63_01832	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
AUC63_01833	ENOG4105E2X	shikimate dehydrogenase
AUC63_01837	ENOG4105CHM	Aminotransferase
AUC63_01842	ENOG4105DQ6	Transposase
AUC63_01845	ENOG4105IG6	Phage terminase, large subunit
AUC63_01876	ENOG4108IMY	Transcriptional regulator
AUC63_01884	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AUC63_01885	ENOG4105CHM	Aminotransferase
AUC63_01886	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AUC63_01887	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AUC63_01888	ENOG4105CH2	amidohydrolase
AUC63_01891	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AUC63_01892	ENOG4105CFH	Aspartokinase
AUC63_01894	ENOG4105ETE	Transcriptional regulator (LacI family
AUC63_01895	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AUC63_01898	ENOG41080S5	HTH_DTXR
AUC63_01899	ENOG4108Z6X	(sortase) family
AUC63_01902	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
AUC63_01903	ENOG4105FDU	atp-dependent rna helicase
AUC63_01904	ENOG4105EE0	oxidoreductase
AUC63_01905	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AUC63_01908	ENOG4108V0P	LemA family
AUC63_01910	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
AUC63_01914	ENOG4105E66	phosphoriboisomerase A
AUC63_01916	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AUC63_01917	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AUC63_01918	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AUC63_01920	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AUC63_01921	ENOG4105CHR	reductase
AUC63_01922	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AUC63_01923	ENOG4105EA8	2-Nitropropane dioxygenase
AUC63_01924	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AUC63_01925	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AUC63_01926	ENOG41067TZ	transcriptional regulator, MarR family
AUC63_01927	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AUC63_01929	ENOG4105C83	adenylosuccinate lyase
AUC63_01930	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
AUC63_01932	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AUC63_01933	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
AUC63_01934	ENOG4105C34	Pseudouridine synthase
AUC63_01936	ENOG4105VND	Ribonuclease
AUC63_01937	ENOG4105DFD	Na H antiporter
AUC63_01938	ENOG4105CTD	carboxy-peptidase
AUC63_01939	ENOG4105C85	amino acid
AUC63_01941	ENOG4105CHR	reductase
AUC63_01943	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AUC63_01945	ENOG4105CV8	reductase
AUC63_01947	ENOG4108EKI	Dehydrogenase
AUC63_01948	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AUC63_01950	ENOG4105C5Q	Transcriptional regulator
AUC63_01951	ENOG4105BZA	Phosphoglycerate kinase
AUC63_01952	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AUC63_01959	ENOG4105ZT7	DNA-entry nuclease
AUC63_01961	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AUC63_01963	ENOG4105F3R	pts system mannose fructose sorbose family iid
AUC63_01964	ENOG4105ETZ	PTS System
AUC63_01967	ENOG41065RQ	ADP-ribosylation crystallin J1
AUC63_01979	ENOG4105E0M	Sulfatase
AUC63_01982	ENOG4105W2C	Glycosyl transferase
AUC63_01983	ENOG4105BZF	Glycosyl transferase (Group 1
AUC63_01984	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AUC63_01985	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AUC63_01986	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
AUC63_01987	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AUC63_01988	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AUC63_01989	ENOG4105CD3	dihydroorotase
AUC63_01990	ENOG4105CXT	aspartate transcarbamylase
AUC63_01995	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AUC63_01996	ENOG4107U5W	ybbr family
AUC63_01998	ENOG4105EEQ	Na H antiporter
AUC63_01999	ENOG4105D4A	Cell wall formation (By similarity)
AUC63_02000	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
AUC63_02002	ENOG4105K8N	protein family UPF0079, ATPase
AUC63_02003	ENOG4108IJ2	phosphate acetyltransferase
AUC63_02004	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AUC63_02006	ENOG410839T	multidrug resistance protein
AUC63_02007	ENOG41080TC	multidrug resistance protein
AUC63_02008	ENOG4105CDA	abc transporter atp-binding protein
AUC63_02009	ENOG4105E5Q	amino acid AbC transporter
AUC63_02010	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AUC63_02012	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AUC63_02013	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AUC63_02015	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AUC63_02016	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AUC63_02017	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AUC63_02020	ENOG4105CP7	Triose-phosphate isomerase
AUC63_02021	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AUC63_02022	ENOG4105KRI	phosphocarrier protein (HPr
AUC63_02024	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AUC63_02025	ENOG4105C3M	thioredoxin reductase
AUC63_02031	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
AUC63_02032	ENOG41086DT	Membrane protein of unknown function
AUC63_02034	ENOG4107YZX	Universal stress protein
AUC63_02036	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AUC63_02037	ENOG4108HM4	ABC transporter
AUC63_02038	ENOG4105D38	putrescine abc transporter
AUC63_02039	ENOG4105F38	ABC transporter, permease
AUC63_02040	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AUC63_02042	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AUC63_02043	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AUC63_02044	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AUC63_02046	ENOG4108JQ7	(ABC) transporter
AUC63_02047	ENOG4105C3U	ABC transporter
AUC63_02048	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AUC63_02051	ENOG4105D6E	homoserine dehydrogenase
AUC63_02052	ENOG4105C28	cystathionine
AUC63_02053	ENOG4105CVG	Homoserine O-transsuccinylase
AUC63_02055	ENOG4105DIH	basic membrane
AUC63_02056	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AUC63_02057	ENOG4105VJV	50s ribosomal protein L35
AUC63_02058	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AUC63_02059	ENOG4105M7K	Involved in the transcription termination process (By similarity)
AUC63_02060	ENOG4108ZSR	alkaline shock protein
AUC63_02061	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AUC63_02062	ENOG4107QYV	phosphohexose isomerase
AUC63_02063	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
AUC63_02065	ENOG4105CSC	Glucose uptake protein
AUC63_02066	ENOG4105BZU	Histidine kinase
AUC63_02067	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AUC63_02069	ENOG4105DZC	cytosine deaminase
AUC63_02070	ENOG4105D9R	oxidoreductase
AUC63_02075	ENOG4105D64	Mechanosensitive ion channel
AUC63_02077	ENOG4105CDA	abc transporter atp-binding protein
AUC63_02078	ENOG4108HW4	amino acid AbC transporter
AUC63_02081	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
AUC63_02088	ENOG4105CHR	reductase
AUC63_02100	ENOG4105DQ6	Transposase
AUC63_02103	ENOG4105M6F	mutator MutT protein
AUC63_02108	ENOG4105E66	phosphoriboisomerase A
AUC63_02110	ENOG4105EDR	glucose galactose transporter
AUC63_02111	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
AUC63_02112	ENOG4105ETE	Transcriptional regulator (LacI family
AUC63_02116	ENOG4105D7K	pfkb domain protein
AUC63_02119	ENOG4108M60	Transcriptional regulator
AUC63_02124	ENOG4105FCD	Major Facilitator
AUC63_02126	ENOG4105CEY	Amp-dependent synthetase and ligase
AUC63_02129	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AUC63_02131	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AUC63_02132	ENOG4105EUJ	GTP cyclohydrolase i
AUC63_02133	ENOG4105EUJ	GTP cyclohydrolase i
AUC63_02143	ENOG4108HCJ	Hydrolase
AUC63_02146	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AUC63_02147	ENOG4105D01	(LipO)protein
AUC63_02149	ENOG4105D7K	pfkb domain protein
AUC63_02150	ENOG4108UHU	Aldolase
AUC63_02151	ENOG4105D2H	Uronic isomerase
AUC63_02152	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
AUC63_02153	ENOG4105DEI	Mannitol dehydrogenase
AUC63_02156	ENOG4107URF	beta-phospho-glucomutase
AUC63_02159	ENOG4105FKQ	transcriptional regulator
AUC63_02166	ENOG4105C19	ABC transporter
AUC63_02167	ENOG4105KA3	membrAne
AUC63_02171	ENOG4105D5Q	Arginine ornithine antiporter
AUC63_02172	ENOG4105DBV	ornithine carbamoyltransferase
AUC63_02173	ENOG4105CEU	Arginine dihydrolase
AUC63_02174	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
AUC63_02175	ENOG4105C59	p-type ATPase
AUC63_02199	ENOG4108XFH	Transcriptional regulator
AUC63_02203	ENOG4105CID	antiterminator
AUC63_02204	ENOG4105CS2	ec 3.2.1.21
AUC63_02205	ENOG41066F8	ROK family
AUC63_02213	ENOG4105MS2	ribosomal subunit Interface protein
AUC63_02214	ENOG41081UC	Inherit from COG: Competence protein
AUC63_02216	ENOG4105CVA	phosphate