locus-tag	class	description
AUC63_00010	COG2176	DNA-directed DNA polymerase activity
AUC63_00011	COG0442	prolyl-tRNA aminoacylation
AUC63_00012	COG0750	zinc metalloprotease
AUC63_00013	COG4589	Belongs to the CDS family
AUC63_00014	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AUC63_00015	COG0561	phosphatase activity
AUC63_00016	COG2246	polysaccharide biosynthetic process
AUC63_00021	COG1811	Na channel or pump
AUC63_00022	COG1979	alcohol dehydrogenase
AUC63_00024	COG1174	glycine betaine transport
AUC63_00026	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AUC63_00028	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AUC63_00029	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AUC63_00029	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AUC63_00030	COG0307	riboflavin synthase, alpha
AUC63_00032	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AUC63_00032	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AUC63_00033	COG2076	Multidrug Resistance protein
AUC63_00034	COG2076	Multidrug Resistance protein
AUC63_00036	COG1435	thymidine kinase activity
AUC63_00039	COG1307	EDD domain protein, DegV family
AUC63_00040	COG0656	L-ascorbic acid biosynthetic process
AUC63_00041	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AUC63_00042	COG2814	Major facilitator Superfamily
AUC63_00045	COG1228	amidohydrolase
AUC63_00046	COG4166	transmembrane transport
AUC63_00047	COG0604	alcohol dehydrogenase
AUC63_00057	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AUC63_00059	COG2252	PERMEase
AUC63_00061	COG0352	thiamine-phosphate diphosphorylase activity
AUC63_00062	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AUC63_00064	COG2814	Major facilitator Superfamily
AUC63_00065	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AUC63_00069	COG1136	(ABC) transporter
AUC63_00069	COG0577	efflux transmembrane transporter activity
AUC63_00071	COG0561	phosphatase activity
AUC63_00072	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AUC63_00072	COG2169	Transcriptional regulator
AUC63_00073	COG0561	phosphatase activity
AUC63_00077	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AUC63_00078	COG0772	Belongs to the SEDS family
AUC63_00080	COG1077	Cell shape determining protein MreB Mrl
AUC63_00081	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AUC63_00086	COG0446	pyridine nucleotide-disulphide oxidoreductase
AUC63_00088	COG0640	Transcriptional regulator
AUC63_00089	COG0628	permease
AUC63_00090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AUC63_00094	COG0386	Belongs to the glutathione peroxidase family
AUC63_00095	COG0588	phosphoglycerate mutase activity
AUC63_00098	COG0492	ferredoxin-NADP+ reductase activity
AUC63_00101	COG1744	ABC transporter substrate-binding protein PnrA-like
AUC63_00104	COG2832	Protein of unknown function (DUF454)
AUC63_00109	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AUC63_00111	COG2814	Major facilitator Superfamily
AUC63_00112	COG0305	Participates in initiation and elongation during chromosome replication
AUC63_00113	COG0359	binds to the 23S rRNA
AUC63_00115	COG4608	Belongs to the ABC transporter superfamily
AUC63_00116	COG0444	Belongs to the ABC transporter superfamily
AUC63_00117	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AUC63_00118	COG0601	transmembrane transport
AUC63_00119	COG4166	transmembrane transport
AUC63_00120	COG0765	amino acid transport
AUC63_00121	COG0765	amino acid transport
AUC63_00122	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AUC63_00123	COG1126	abc transporter atp-binding protein
AUC63_00126	COG0194	GDP metabolic process
AUC63_00127	COG1268	BioY protein
AUC63_00128	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AUC63_00128	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AUC63_00133	COG2211	Major facilitator Superfamily
AUC63_00134	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AUC63_00137	COG3973	AAA domain
AUC63_00141	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AUC63_00143	COG1696	Membrane protein involved in D-alanine export
AUC63_00147	COG2337	Toxic component of a toxin-antitoxin (TA) module
AUC63_00150	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AUC63_00151	COG0504	CTP synthase activity
AUC63_00153	COG3343	RNA polymerase activity
AUC63_00154	COG0561	phosphatase activity
AUC63_00155	COG1078	dGTPase activity
AUC63_00157	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AUC63_00158	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AUC63_00162	COG0745	RESPONSE REGULATOR receiver
AUC63_00168	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AUC63_00169	COG0629	single-stranded DNA binding
AUC63_00170	COG0360	Binds together with S18 to 16S ribosomal RNA
AUC63_00173	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AUC63_00175	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AUC63_00176	COG1051	belongs to the nudix hydrolase family
AUC63_00179	COG2814	Major facilitator Superfamily
AUC63_00180	COG1064	alcohol dehydrogenase
AUC63_00181	COG1074	ATP-dependent DNA helicase activity
AUC63_00182	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AUC63_00185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AUC63_00186	COG0531	amino acid
AUC63_00188	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AUC63_00190	COG1902	pentaerythritol trinitrate reductase activity
AUC63_00191	COG0626	cystathionine gamma-synthase activity
AUC63_00195	COG2244	polysaccharide biosynthetic process
AUC63_00197	COG0438	transferase activity, transferring glycosyl groups
AUC63_00198	COG0495	leucyl-tRNA aminoacylation
AUC63_00199	COG0671	phosphoesterase, PA-phosphatase related
AUC63_00201	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AUC63_00206	COG2723	6-phospho-beta-galactosidase activity
AUC63_00210	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AUC63_00212	COG2801	Transposase and inactivated derivatives
AUC63_00214	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AUC63_00216	COG0024	Methionine aminopeptidase
AUC63_00218	COG1316	TRANSCRIPTIONal
AUC63_00220	COG2205	protein histidine kinase activity
AUC63_00221	COG0745	RESPONSE REGULATOR receiver
AUC63_00222	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AUC63_00225	COG2207	Transcriptional regulator
AUC63_00229	COG0308	aminopeptidase N
AUC63_00230	COG0833	amino acid
AUC63_00231	COG2040	homocysteine
AUC63_00232	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AUC63_00233	COG0542	response to heat
AUC63_00236	COG0395	ABC-type sugar transport system, permease component
AUC63_00237	COG1175	transmembrane transport
AUC63_00238	COG3842	ATPase activity
AUC63_00260	COG0438	transferase activity, transferring glycosyl groups
AUC63_00266	COG2084	Dehydrogenase
AUC63_00267	COG1028	Short-chain dehydrogenase reductase Sdr
AUC63_00269	COG1620	l-lactate permease
AUC63_00270	COG4989	oxidoreductase activity
AUC63_00271	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AUC63_00272	COG2233	PERMEase
AUC63_00275	COG1956	GAF domain-containing protein
AUC63_00278	COG1132	(ABC) transporter
AUC63_00279	COG1132	(ABC) transporter
AUC63_00280	COG1132	(ABC) transporter
AUC63_00281	COG0747	negative chemotaxis
AUC63_00282	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AUC63_00283	COG0601	transmembrane transport
AUC63_00284	COG4608	Belongs to the ABC transporter superfamily
AUC63_00285	COG0444	Belongs to the ABC transporter superfamily
AUC63_00286	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AUC63_00287	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AUC63_00288	COG2211	Major facilitator Superfamily
AUC63_00288	COG2190	(PTS) system
AUC63_00292	COG0436	Aminotransferase
AUC63_00294	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AUC63_00295	COG2723	6-phospho-beta-galactosidase activity
AUC63_00296	COG2723	6-phospho-beta-galactosidase activity
AUC63_00297	COG1447	Phosphotransferase system cellobiose-specific component IIA
AUC63_00298	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AUC63_00299	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AUC63_00302	COG1216	Glycosyl transferase, family 2
AUC63_00305	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AUC63_00314	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AUC63_00315	COG1737	Transcriptional regulator
AUC63_00317	COG0656	L-ascorbic acid biosynthetic process
AUC63_00318	COG2261	transglycosylase associated protein
AUC63_00331	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AUC63_00332	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AUC63_00335	COG0037	tRNA processing
AUC63_00337	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AUC63_00338	COG2244	polysaccharide biosynthetic process
AUC63_00339	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AUC63_00340	COG0193	aminoacyl-tRNA hydrolase activity
AUC63_00342	COG0058	SHG alpha-glucan phosphorylase activity
AUC63_00343	COG0297	glycogen (starch) synthase activity
AUC63_00344	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AUC63_00346	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AUC63_00348	COG1511	domain protein
AUC63_00348	COG1511	domain protein
AUC63_00349	COG1309	transcriptional regulator
AUC63_00352	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AUC63_00353	COG0477	Major facilitator Superfamily
AUC63_00356	COG0667	Aldo Keto reductase
AUC63_00358	COG2115	Belongs to the xylose isomerase family
AUC63_00360	COG2211	Major facilitator Superfamily
AUC63_00361	COG3507	Belongs to the glycosyl hydrolase 43 family
AUC63_00366	COG2818	Glycosylase
AUC63_00367	COG1968	undecaprenyl-diphosphatase activity
AUC63_00370	COG1695	Transcriptional regulator
AUC63_00371	COG1983	PspC domain protein
AUC63_00372	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AUC63_00373	COG0737	Belongs to the 5'-nucleotidase family
AUC63_00376	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AUC63_00378	COG2723	6-phospho-beta-galactosidase activity
AUC63_00379	COG2723	6-phospho-beta-galactosidase activity
AUC63_00380	COG1263	PTS System
AUC63_00380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AUC63_00381	COG1316	TRANSCRIPTIONal
AUC63_00382	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AUC63_00383	COG2131	deaminase
AUC63_00384	COG4466	Protein conserved in bacteria
AUC63_00385	COG1253	flavin adenine dinucleotide binding
AUC63_00386	COG1253	flavin adenine dinucleotide binding
AUC63_00387	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AUC63_00388	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AUC63_00389	COG0084	hydrolase, TatD family'
AUC63_00391	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AUC63_00391	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AUC63_00404	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AUC63_00408	COG1368	sulfuric ester hydrolase activity
AUC63_00409	COG2153	protein acetylation
AUC63_00412	COG0187	DNA topoisomerase II activity
AUC63_00413	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AUC63_00414	COG2501	S4 domain
AUC63_00415	COG0592	DNA-directed DNA polymerase activity
AUC63_00416	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AUC63_00417	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AUC63_00418	COG0594	ribonuclease P activity
AUC63_00419	COG0706	membrane insertase activity
AUC63_00421	COG1120	ATPase activity
AUC63_00423	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AUC63_00426	COG0569	domain protein
AUC63_00427	COG1113	amino acid transport
AUC63_00431	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AUC63_00433	COG0446	pyridine nucleotide-disulphide oxidoreductase
AUC63_00435	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AUC63_00436	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AUC63_00438	COG1136	(ABC) transporter
AUC63_00439	COG0577	efflux transmembrane transporter activity
AUC63_00440	COG2409	Drug exporters of the RND superfamily
AUC63_00440	COG1033	growth of symbiont in host cell
AUC63_00441	COG0561	phosphatase activity
AUC63_00443	COG0328	RNA-DNA hybrid ribonuclease activity
AUC63_00447	COG3152	Membrane
AUC63_00448	COG2252	PERMEase
AUC63_00456	COG1881	PFAM PEBP family protein
AUC63_00470	COG1476	TRANSCRIPTIONal
AUC63_00475	COG0517	IMP dehydrogenase activity
AUC63_00475	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AUC63_00476	COG2723	6-phospho-beta-galactosidase activity
AUC63_00480	COG0697	spore germination
AUC63_00483	COG1744	ABC transporter substrate-binding protein PnrA-like
AUC63_00484	COG0137	argininosuccinate synthase activity
AUC63_00485	COG0165	Argininosuccinate lyase
AUC63_00486	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AUC63_00487	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AUC63_00489	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AUC63_00490	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AUC63_00491	COG0505	Belongs to the CarA family
AUC63_00492	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AUC63_00496	COG1131	(ABC) transporter
AUC63_00501	COG0789	Transcriptional regulator
AUC63_00504	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AUC63_00506	COG0697	spore germination
AUC63_00507	COG1744	ABC transporter substrate-binding protein PnrA-like
AUC63_00511	COG1846	Transcriptional regulator
AUC63_00512	COG1132	(ABC) transporter
AUC63_00514	COG0656	L-ascorbic acid biosynthetic process
AUC63_00516	COG4619	ABC transporter
AUC63_00517	COG0390	transport system, permease component
AUC63_00519	COG1131	(ABC) transporter
AUC63_00521	COG1126	abc transporter atp-binding protein
AUC63_00522	COG0765	amino acid transport
AUC63_00524	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AUC63_00525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AUC63_00526	COG1254	Belongs to the acylphosphatase family
AUC63_00528	COG0392	lysyltransferase activity
AUC63_00528	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AUC63_00530	COG0628	permease
AUC63_00536	COG1113	amino acid transport
AUC63_00541	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AUC63_00544	COG2855	membrane
AUC63_00545	COG3620	sequence-specific DNA binding
AUC63_00547	COG2855	membrane
AUC63_00548	COG0583	DNA-binding transcription factor activity
AUC63_00550	COG2070	2-Nitropropane dioxygenase
AUC63_00553	COG1228	amidohydrolase
AUC63_00554	COG0531	amino acid
AUC63_00556	COG3223	Belongs to the PsiE family
AUC63_00558	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AUC63_00560	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AUC63_00562	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AUC63_00563	COG4166	transmembrane transport
AUC63_00564	COG2267	carboxylic ester hydrolase activity
AUC63_00566	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AUC63_00569	COG0477	Major facilitator Superfamily
AUC63_00570	COG4975	Glucose uptake
AUC63_00572	COG0531	amino acid
AUC63_00573	COG1113	amino acid transport
AUC63_00574	COG0531	amino acid
AUC63_00575	COG0252	asparaginase activity
AUC63_00576	COG4443	Transcriptional Coactivator p15 (PC4)
AUC63_00578	COG2226	methyltransferase
AUC63_00579	COG1335	isochorismatase
AUC63_00580	COG2050	protein possibly involved in aromatic compounds catabolism
AUC63_00581	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AUC63_00582	COG0318	PFAM AMP-dependent synthetase and ligase
AUC63_00585	COG0745	RESPONSE REGULATOR receiver
AUC63_00586	COG5002	protein histidine kinase activity
AUC63_00594	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AUC63_00595	COG1194	a g-specific adenine glycosylase
AUC63_00597	COG0357	Ribosomal RNA small subunit methyltransferase G
AUC63_00598	COG1192	Involved in chromosome partitioning
AUC63_00599	COG1475	DNA binding
AUC63_00600	COG4481	Protein conserved in bacteria
AUC63_00601	COG0012	GTP binding
AUC63_00603	COG0745	RESPONSE REGULATOR receiver
AUC63_00605	COG1686	Belongs to the peptidase S11 family
AUC63_00615	COG3104	oligopeptide transport
AUC63_00616	COG0477	Major facilitator Superfamily
AUC63_00617	COG4975	Glucose uptake
AUC63_00626	COG3091	SprT-like family
AUC63_00627	COG2755	lipolytic protein G-D-S-L family
AUC63_00627	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AUC63_00630	COG1846	Transcriptional regulator
AUC63_00632	COG1121	(ABC) transporter
AUC63_00633	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AUC63_00634	COG0488	(ABC) transporter
AUC63_00635	COG0534	Mate efflux family protein
AUC63_00638	COG3940	Belongs to the glycosyl hydrolase 43 family
AUC63_00643	COG2160	L-arabinose isomerase activity
AUC63_00644	COG0656	L-ascorbic acid biosynthetic process
AUC63_00651	COG0765	amino acid transport
AUC63_00659	COG1215	transferase activity, transferring glycosyl groups
AUC63_00660	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AUC63_00661	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AUC63_00664	COG1418	mRNA catabolic process
AUC63_00665	COG2814	Major facilitator Superfamily
AUC63_00666	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AUC63_00667	COG2188	Transcriptional regulator
AUC63_00668	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AUC63_00671	COG0463	Glycosyl transferase, family 2
AUC63_00671	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AUC63_00675	COG1442	glycosyl transferase family 8
AUC63_00675	COG1216	Glycosyl transferase, family 2
AUC63_00676	COG1215	transferase activity, transferring glycosyl groups
AUC63_00677	COG2801	Transposase and inactivated derivatives
AUC63_00680	COG5039	Polysaccharide pyruvyl transferase
AUC63_00688	COG3590	peptidase
AUC63_00689	COG1454	alcohol dehydrogenase
AUC63_00689	COG1012	belongs to the aldehyde dehydrogenase family
AUC63_00691	COG0708	Exodeoxyribonuclease III
AUC63_00695	COG0588	phosphoglycerate mutase activity
AUC63_00699	COG1132	(ABC) transporter
AUC63_00700	COG1132	(ABC) transporter
AUC63_00705	COG0110	maltose O-acetyltransferase activity
AUC63_00707	COG1482	cell wall glycoprotein biosynthetic process
AUC63_00708	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AUC63_00709	COG3442	glutamine amidotransferase
AUC63_00711	COG1435	thymidine kinase activity
AUC63_00712	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AUC63_00713	COG2890	protein-(glutamine-N5) methyltransferase activity
AUC63_00714	COG0009	L-threonylcarbamoyladenylate synthase
AUC63_00715	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AUC63_00716	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AUC63_00717	COG0702	epimerase
AUC63_00719	COG2233	PERMEase
AUC63_00720	COG0356	it plays a direct role in the translocation of protons across the membrane
AUC63_00721	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AUC63_00722	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AUC63_00723	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AUC63_00724	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AUC63_00725	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AUC63_00726	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AUC63_00727	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AUC63_00728	COG1876	peptidase activity
AUC63_00729	COG1428	Deoxynucleoside kinase
AUC63_00730	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AUC63_00735	COG4463	regulation of RNA biosynthetic process
AUC63_00736	COG0542	response to heat
AUC63_00737	COG0085	RNA polymerase activity
AUC63_00741	COG1979	alcohol dehydrogenase
AUC63_00745	COG1309	transcriptional regulator
AUC63_00746	COG0500	methyltransferase
AUC63_00755	COG3620	sequence-specific DNA binding
AUC63_00757	COG2807	transmembrane transport
AUC63_00759	COG2813	Specifically methylates the guanine in position
AUC63_00760	COG0590	tRNA wobble adenosine to inosine editing
AUC63_00761	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AUC63_00766	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AUC63_00767	COG3870	Protein conserved in bacteria
AUC63_00771	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AUC63_00772	COG1214	PFAM Peptidase M22, glycoprotease
AUC63_00773	COG0456	acetyltransferase
AUC63_00775	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AUC63_00776	COG0142	geranyltranstransferase activity
AUC63_00777	COG0051	transcription antitermination factor activity, RNA binding
AUC63_00778	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AUC63_00780	COG0089	rRNA binding
AUC63_00781	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AUC63_00782	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AUC63_00783	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AUC63_00784	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AUC63_00785	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AUC63_00786	COG0255	Belongs to the universal ribosomal protein uL29 family
AUC63_00788	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AUC63_00789	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AUC63_00790	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AUC63_00791	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AUC63_00792	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AUC63_00793	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AUC63_00794	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AUC63_00795	COG1841	ribosomal large subunit assembly
AUC63_00796	COG0200	Binds to the 23S rRNA
AUC63_00799	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AUC63_00800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AUC63_00802	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AUC63_00803	COG0202	RNA polymerase activity
AUC63_00804	COG0203	ribosomal protein L17
AUC63_00809	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AUC63_00812	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AUC63_00817	COG0583	DNA-binding transcription factor activity
AUC63_00818	COG0114	fumarate hydratase activity
AUC63_00819	COG1053	succinate dehydrogenase
AUC63_00820	COG0471	metal ion transport
AUC63_00821	COG0039	L-malate dehydrogenase activity
AUC63_00822	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AUC63_00823	COG0215	cysteine-tRNA ligase activity
AUC63_00824	COG0626	cystathionine gamma-synthase activity
AUC63_00825	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AUC63_00826	COG1464	Belongs to the NlpA lipoprotein family
AUC63_00827	COG1854	S-ribosylhomocysteine lyase activity
AUC63_00828	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AUC63_00829	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AUC63_00832	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AUC63_00833	COG0250	Participates in transcription elongation, termination and antitermination
AUC63_00834	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AUC63_00835	COG0081	regulation of translation
AUC63_00836	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AUC63_00837	COG0222	ribosome binding
AUC63_00839	COG1121	(ABC) transporter
AUC63_00840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AUC63_00841	COG0803	Belongs to the bacterial solute-binding protein 9 family
AUC63_00842	COG1252	NADH dehydrogenase
AUC63_00844	COG1122	ATPase activity
AUC63_00845	COG1122	ATPase activity
AUC63_00847	COG0101	tRNA pseudouridine synthase activity
AUC63_00848	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AUC63_00850	COG4221	oxidoreductase activity
AUC63_00853	COG0028	Belongs to the TPP enzyme family
AUC63_00856	COG1573	uracil-dna glycosylase
AUC63_00862	COG0671	phosphoesterase, PA-phosphatase related
AUC63_00864	COG2814	Major facilitator Superfamily
AUC63_00865	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AUC63_00867	COG1660	Displays ATPase and GTPase activities
AUC63_00868	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AUC63_00869	COG1481	regulation of sporulation
AUC63_00870	COG0740	serine-type endopeptidase activity
AUC63_00873	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AUC63_00873	COG1263	PTS System
AUC63_00875	COG1914	H( )-stimulated, divalent metal cation uptake system
AUC63_00879	COG0039	L-malate dehydrogenase activity
AUC63_00880	COG0028	Belongs to the TPP enzyme family
AUC63_00881	COG3527	Alpha-acetolactate decarboxylase
AUC63_00883	COG1388	LysM domain
AUC63_00883	COG3942	CHAP domain
AUC63_00884	COG0791	NLP P60 protein
AUC63_00886	COG0756	dUTP diphosphatase activity
AUC63_00888	COG4956	integral membrane protein (PIN domain superfamily)
AUC63_00890	COG0653	protein targeting
AUC63_00891	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AUC63_00895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AUC63_00897	COG1733	regulation of RNA biosynthetic process
AUC63_00898	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AUC63_00899	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AUC63_00899	COG0072	phenylalanine-tRNA ligase activity
AUC63_00900	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AUC63_00901	COG0514	ATP-dependent DNA helicase (RecQ)
AUC63_00902	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AUC63_00904	COG0768	penicillin binding
AUC63_00905	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AUC63_00908	COG1940	carbohydrate kinase activity
AUC63_00909	COG3409	Peptidoglycan-binding domain 1 protein
AUC63_00909	COG5632	N-Acetylmuramoyl-L-alanine amidase
AUC63_00910	COG3942	CHAP domain
AUC63_00914	COG0584	glycerophosphoryl diester phosphodiesterase
AUC63_00915	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AUC63_00916	COG0789	Transcriptional regulator
AUC63_00917	COG0174	glutamine synthetase
AUC63_00922	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AUC63_00923	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AUC63_00924	COG1472	Belongs to the glycosyl hydrolase 3 family
AUC63_00926	COG1132	(ABC) transporter
AUC63_00927	COG0778	Nitroreductase
AUC63_00928	COG1169	isochorismate synthase
AUC63_00929	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AUC63_00930	COG0596	Alpha beta hydrolase
AUC63_00931	COG4948	Mandelate Racemase Muconate Lactonizing
AUC63_00935	COG0737	Belongs to the 5'-nucleotidase family
AUC63_00936	COG4470	Protein conserved in bacteria
AUC63_00937	COG0647	UMP catabolic process
AUC63_00938	COG4166	transmembrane transport
AUC63_00939	COG0673	inositol 2-dehydrogenase activity
AUC63_00943	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AUC63_00944	COG0573	inorganic phosphate transmembrane transporter activity
AUC63_00945	COG0581	inorganic phosphate transmembrane transporter activity
AUC63_00946	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AUC63_00947	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AUC63_00948	COG0704	Plays a role in the regulation of phosphate uptake
AUC63_00949	COG2137	regulation of response to DNA damage stimulus
AUC63_00954	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AUC63_00956	COG5506	Protein of unknown function (DUF1694)
AUC63_00958	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AUC63_00980	COG1272	protein, Hemolysin III
AUC63_00987	COG0525	valine-tRNA ligase activity
AUC63_00989	COG0285	dihydrofolate synthase activity
AUC63_00993	COG0488	(ABC) transporter
AUC63_00994	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AUC63_00995	COG0459	protein refolding
AUC63_00996	COG0531	amino acid
AUC63_00998	COG1181	Belongs to the D-alanine--D-alanine ligase family
AUC63_00999	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AUC63_01000	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AUC63_01002	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AUC63_01003	COG1713	HD superfamily hydrolase involved in NAD metabolism
AUC63_01004	COG0799	negative regulation of ribosome biogenesis
AUC63_01005	COG2226	methyltransferase
AUC63_01006	COG1323	Belongs to the UPF0348 family
AUC63_01008	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AUC63_01009	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AUC63_01029	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AUC63_01031	COG0363	glucosamine-6-phosphate deaminase activity
AUC63_01032	COG0776	regulation of translation
AUC63_01034	COG0577	efflux transmembrane transporter activity
AUC63_01035	COG1136	(ABC) transporter
AUC63_01038	COG4720	Psort location CytoplasmicMembrane, score
AUC63_01039	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AUC63_01040	COG1570	exodeoxyribonuclease VII activity
AUC63_01042	COG0142	geranyltranstransferase activity
AUC63_01043	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AUC63_01044	COG1438	arginine binding
AUC63_01045	COG0497	DNA recombination
AUC63_01047	COG0194	GDP metabolic process
AUC63_01049	COG0586	Pfam SNARE associated Golgi protein
AUC63_01050	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AUC63_01051	COG1098	S1 RNA binding domain
AUC63_01074	COG4684	Psort location CytoplasmicMembrane, score
AUC63_01075	COG1271	oxidase subunit
AUC63_01076	COG1294	oxidase, subunit
AUC63_01077	COG4988	ABC transporter
AUC63_01078	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AUC63_01079	COG1388	LysM domain
AUC63_01079	COG1705	Flagellar rod assembly protein muramidase FlgJ
AUC63_01080	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AUC63_01084	COG0494	nUDIX hydrolase
AUC63_01086	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AUC63_01087	COG0346	lactoylglutathione lyase activity
AUC63_01088	COG0400	carboxylic ester hydrolase activity
AUC63_01090	COG0741	lytic transglycosylase activity
AUC63_01094	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AUC63_01095	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AUC63_01096	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AUC63_01098	COG4120	Belongs to the binding-protein-dependent transport system permease family
AUC63_01100	COG0038	chloride channel
AUC63_01101	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AUC63_01102	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AUC63_01103	COG1307	EDD domain protein, DegV family
AUC63_01104	COG2190	(PTS) system
AUC63_01104	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AUC63_01104	COG1263	PTS System
AUC63_01107	COG2003	Belongs to the UPF0758 family
AUC63_01108	COG1077	Cell shape determining protein MreB Mrl
AUC63_01109	COG1792	Involved in formation and maintenance of cell shape
AUC63_01110	COG3338	carbonate dehydratase activity
AUC63_01112	COG0765	amino acid transport
AUC63_01113	COG1126	abc transporter atp-binding protein
AUC63_01114	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AUC63_01116	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AUC63_01117	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AUC63_01118	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AUC63_01121	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AUC63_01123	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AUC63_01124	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AUC63_01125	COG0138	bifunctional purine biosynthesis protein purh
AUC63_01126	COG0151	Belongs to the GarS family
AUC63_01127	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AUC63_01130	COG0446	pyridine nucleotide-disulphide oxidoreductase
AUC63_01133	COG0833	amino acid
AUC63_01135	COG2264	protein methyltransferase activity
AUC63_01136	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AUC63_01138	COG2001	Belongs to the MraZ family
AUC63_01139	COG0275	rRNA processing
AUC63_01142	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AUC63_01143	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AUC63_01144	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AUC63_01145	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AUC63_01146	COG0849	cell division
AUC63_01148	COG1799	cell septum assembly
AUC63_01151	COG3599	regulation of cell shape
AUC63_01155	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AUC63_01156	COG0217	transcriptional regulatory protein
AUC63_01157	COG2252	PERMEase
AUC63_01158	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AUC63_01166	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AUC63_01167	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AUC63_01168	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AUC63_01169	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AUC63_01169	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AUC63_01170	COG0631	protein serine/threonine phosphatase activity
AUC63_01171	COG0515	serine threonine protein kinase
AUC63_01171	COG2815	serine threonine protein kinase
AUC63_01172	COG1162	GTPase activity
AUC63_01173	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AUC63_01175	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AUC63_01177	COG1461	Dihydroxyacetone kinase
AUC63_01180	COG0438	transferase activity, transferring glycosyl groups
AUC63_01182	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AUC63_01183	COG0416	fatty acid biosynthetic process
AUC63_01184	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AUC63_01185	COG0571	ribonuclease III activity
AUC63_01186	COG1196	nuclear chromosome segregation
AUC63_01187	COG0552	protein localization to endoplasmic reticulum
AUC63_01189	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AUC63_01193	COG0228	four-way junction DNA binding
AUC63_01197	COG0588	phosphoglycerate mutase activity
AUC63_01198	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AUC63_01199	COG0336	Belongs to the RNA methyltransferase TrmD family
AUC63_01200	COG0335	large ribosomal subunit rRNA binding
AUC63_01202	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AUC63_01203	COG1942	4-Oxalocrotonate Tautomerase
AUC63_01204	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AUC63_01206	COG1428	Deoxynucleoside kinase
AUC63_01207	COG1970	mechanosensitive ion channel activity
AUC63_01208	COG0561	phosphatase activity
AUC63_01221	COG3853	Toxic anion resistance protein (TelA)
AUC63_01222	COG1393	Belongs to the ArsC family
AUC63_01223	COG4862	establishment of competence for transformation
AUC63_01224	COG2723	6-phospho-beta-galactosidase activity
AUC63_01225	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AUC63_01226	COG1447	Phosphotransferase system cellobiose-specific component IIA
AUC63_01227	COG2723	6-phospho-beta-galactosidase activity
AUC63_01228	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AUC63_01230	COG1164	Oligoendopeptidase f
AUC63_01231	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AUC63_01234	COG1609	Transcriptional regulator
AUC63_01235	COG0006	proline dipeptidase activity
AUC63_01249	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AUC63_01250	COG3425	synthase
AUC63_01253	COG0860	N-Acetylmuramoyl-L-alanine amidase
AUC63_01254	COG0124	histidyl-tRNA synthetase
AUC63_01255	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AUC63_01257	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AUC63_01258	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AUC63_01259	COG1610	YqeY-like protein
AUC63_01260	COG1702	phosphate starvation-inducible protein PhoH
AUC63_01261	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AUC63_01262	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AUC63_01263	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AUC63_01264	COG1381	Involved in DNA repair and RecF pathway recombination
AUC63_01267	COG0752	glycyl-tRNA synthetase alpha subunit
AUC63_01268	COG0751	glycine-tRNA ligase activity
AUC63_01272	COG2706	6-phosphogluconolactonase activity
AUC63_01273	COG0628	permease
AUC63_01275	COG1674	ftsk spoiiie
AUC63_01277	COG4152	abc transporter atp-binding protein
AUC63_01278	COG1668	transmembrane transport
AUC63_01281	COG0322	excinuclease ABC activity
AUC63_01282	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AUC63_01283	COG1739	Uncharacterized protein family UPF0029
AUC63_01287	COG0517	IMP dehydrogenase activity
AUC63_01287	COG0516	GMP reductase activity
AUC63_01288	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AUC63_01289	COG0632	four-way junction helicase activity
AUC63_01290	COG2255	four-way junction helicase activity
AUC63_01291	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AUC63_01298	COG0343	queuine tRNA-ribosyltransferase activity
AUC63_01299	COG1862	Preprotein translocase
AUC63_01300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AUC63_01301	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AUC63_01302	COG0513	Belongs to the DEAD box helicase family
AUC63_01304	COG1929	Belongs to the glycerate kinase type-1 family
AUC63_01305	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AUC63_01309	COG3906	Belongs to the UPF0473 family
AUC63_01311	COG2333	competence protein COMEC
AUC63_01311	COG0658	competence protein
AUC63_01312	COG1466	dna polymerase III delta subunit
AUC63_01313	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AUC63_01314	COG0268	Binds directly to 16S ribosomal RNA
AUC63_01319	COG0544	peptidyl-prolyl cis-trans isomerase activity
AUC63_01320	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AUC63_01321	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AUC63_01325	COG1193	negative regulation of DNA recombination
AUC63_01329	COG3118	belongs to the thioredoxin family
AUC63_01330	COG0187	DNA topoisomerase II activity
AUC63_01331	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AUC63_01332	COG3527	Alpha-acetolactate decarboxylase
AUC63_01334	COG1473	amidohydrolase
AUC63_01337	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AUC63_01341	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AUC63_01342	COG3201	nicotinamide mononucleotide transporter
AUC63_01350	COG0277	FAD linked oxidase domain protein
AUC63_01351	COG0277	FAD linked oxidase domain protein
AUC63_01352	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AUC63_01354	COG3321	synthase
AUC63_01354	COG0604	alcohol dehydrogenase
AUC63_01358	COG2801	Transposase and inactivated derivatives
AUC63_01367	COG2801	Transposase and inactivated derivatives
AUC63_01372	COG0277	FAD linked oxidase domain protein
AUC63_01373	COG0436	Aminotransferase
AUC63_01376	COG1464	Belongs to the NlpA lipoprotein family
AUC63_01379	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AUC63_01380	COG0351	phosphomethylpyrimidine kinase
AUC63_01381	COG0352	thiamine-phosphate diphosphorylase activity
AUC63_01386	COG1028	Short-chain dehydrogenase reductase Sdr
AUC63_01388	COG1940	carbohydrate kinase activity
AUC63_01405	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AUC63_01406	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AUC63_01409	COG2357	RelA SpoT domain protein
AUC63_01410	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AUC63_01411	COG0564	pseudouridine synthase activity
AUC63_01412	COG2239	Acts as a magnesium transporter
AUC63_01413	COG2814	Major facilitator Superfamily
AUC63_01418	COG0488	(ABC) transporter
AUC63_01425	COG0583	DNA-binding transcription factor activity
AUC63_01427	COG0656	L-ascorbic acid biosynthetic process
AUC63_01428	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AUC63_01430	COG1846	Transcriptional regulator
AUC63_01441	COG0384	phenazine biosynthesis protein PhzF
AUC63_01443	COG1621	beta-fructofuranosidase activity
AUC63_01444	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AUC63_01445	COG0287	Prephenate dehydrogenase
AUC63_01447	COG0738	Major facilitator superfamily
AUC63_01448	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AUC63_01455	COG1304	FMN binding
AUC63_01458	COG0779	Required for maturation of 30S ribosomal subunits
AUC63_01459	COG0195	Participates in both transcription termination and antitermination
AUC63_01460	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AUC63_01462	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AUC63_01463	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AUC63_01464	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AUC63_01465	COG1252	NADH dehydrogenase
AUC63_01467	COG0196	riboflavin kinase activity
AUC63_01469	COG3142	Participates in the control of copper homeostasis
AUC63_01472	COG2270	Major facilitator Superfamily
AUC63_01473	COG1307	EDD domain protein, DegV family
AUC63_01474	COG1307	EDD domain protein, DegV family
AUC63_01475	COG2755	lipolytic protein G-D-S-L family
AUC63_01477	COG4479	Belongs to the UPF0346 family
AUC63_01479	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AUC63_01480	COG0758	DNA mediated transformation
AUC63_01481	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AUC63_01482	COG4974	Belongs to the 'phage' integrase family
AUC63_01484	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AUC63_01485	COG1227	inorganic diphosphatase activity
AUC63_01488	COG4175	Glycine betaine
AUC63_01488	COG3448	diguanylate cyclase activity
AUC63_01491	COG0446	pyridine nucleotide-disulphide oxidoreductase
AUC63_01492	COG1464	Belongs to the NlpA lipoprotein family
AUC63_01493	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AUC63_01494	COG1597	lipid kinase activity
AUC63_01496	COG1011	Hydrolase
AUC63_01503	COG0242	peptide deformylase activity
AUC63_01504	COG4476	Belongs to the UPF0223 family
AUC63_01505	COG0483	inositol monophosphate 1-phosphatase activity
AUC63_01507	COG0772	Belongs to the SEDS family
AUC63_01508	COG4471	UPF0298 protein
AUC63_01509	COG0742	ribosomal rna small subunit methyltransferase
AUC63_01510	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AUC63_01511	COG3480	Lon protease (S16) C-terminal proteolytic domain
AUC63_01512	COG0477	Major facilitator Superfamily
AUC63_01514	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AUC63_01515	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AUC63_01516	COG0358	DNA primase activity
AUC63_01517	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AUC63_01523	COG0745	RESPONSE REGULATOR receiver
AUC63_01524	COG5002	protein histidine kinase activity
AUC63_01525	COG0572	uridine kinase
AUC63_01526	COG1363	Peptidase, m42
AUC63_01527	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AUC63_01529	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AUC63_01530	COG0670	Belongs to the BI1 family
AUC63_01531	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AUC63_01531	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AUC63_01532	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AUC63_01533	COG0237	dephospho-CoA kinase activity
AUC63_01535	COG1484	DNA-dependent DNA replication
AUC63_01538	COG0745	RESPONSE REGULATOR receiver
AUC63_01539	COG5002	protein histidine kinase activity
AUC63_01541	COG3942	CHAP domain
AUC63_01541	COG1705	Flagellar rod assembly protein muramidase FlgJ
AUC63_01543	COG0531	amino acid
AUC63_01546	COG0706	membrane insertase activity
AUC63_01547	COG1028	Short-chain dehydrogenase reductase Sdr
AUC63_01548	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AUC63_01550	COG1304	FMN binding
AUC63_01554	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AUC63_01554	COG1199	ATP-dependent helicase activity
AUC63_01556	COG0017	Asparaginyl-tRNA synthetase
AUC63_01557	COG3935	DnaD domain protein
AUC63_01559	COG3331	DNA recombination
AUC63_01560	COG4474	Belongs to the UPF0398 family
AUC63_01561	COG3599	regulation of cell shape
AUC63_01563	COG0116	Belongs to the methyltransferase superfamily
AUC63_01565	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AUC63_01569	COG0556	nucleotide-excision repair
AUC63_01571	COG0439	Biotin carboxylase
AUC63_01572	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AUC63_01573	COG0825	malonyl-CoA metabolic process
AUC63_01574	COG3104	oligopeptide transport
AUC63_01575	COG0363	glucosamine-6-phosphate deaminase activity
AUC63_01577	COG0537	adenosine 5'-monophosphoramidase activity
AUC63_01578	COG1131	(ABC) transporter
AUC63_01580	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AUC63_01581	COG1719	4-vinyl reductase, 4VR
AUC63_01582	COG1397	ADP-ribosylglycohydrolase
AUC63_01587	COG0446	pyridine nucleotide-disulphide oxidoreductase
AUC63_01588	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
AUC63_01589	COG1349	DNA-binding transcription factor activity
AUC63_01590	COG1105	Belongs to the carbohydrate kinase PfkB family
AUC63_01591	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AUC63_01591	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AUC63_01591	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AUC63_01593	COG1609	Transcriptional regulator
AUC63_01595	COG0306	phosphate transporter
AUC63_01597	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AUC63_01599	COG2723	6-phospho-beta-galactosidase activity
AUC63_01603	COG0531	amino acid
AUC63_01605	COG0481	GTPase activity
AUC63_01611	COG1028	Short-chain dehydrogenase reductase Sdr
AUC63_01612	COG4708	membrane
AUC63_01614	COG0531	amino acid
AUC63_01615	COG4221	oxidoreductase activity
AUC63_01616	COG0583	DNA-binding transcription factor activity
AUC63_01617	COG0281	malic enzyme
AUC63_01619	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AUC63_01623	COG1136	(ABC) transporter
AUC63_01624	COG0577	efflux transmembrane transporter activity
AUC63_01628	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AUC63_01629	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AUC63_01633	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AUC63_01635	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AUC63_01636	COG2384	SAM-dependent methyltransferase
AUC63_01637	COG0071	Belongs to the small heat shock protein (HSP20) family
AUC63_01638	COG0457	Tetratricopeptide repeat
AUC63_01647	COG0419	ATPase involved in DNA repair
AUC63_01648	COG0420	3'-5' exonuclease activity
AUC63_01650	COG2807	transmembrane transport
AUC63_01651	COG4720	Psort location CytoplasmicMembrane, score
AUC63_01652	COG0351	phosphomethylpyrimidine kinase
AUC63_01654	COG1160	GTP binding
AUC63_01655	COG0539	negative regulation of cytoplasmic translation
AUC63_01656	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AUC63_01658	COG0514	ATP-dependent DNA helicase (RecQ)
AUC63_01660	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AUC63_01663	COG1187	pseudouridine synthase activity
AUC63_01664	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AUC63_01665	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AUC63_01668	COG2996	Protein conserved in bacteria
AUC63_01670	COG0475	glutathione-regulated potassium exporter activity
AUC63_01672	COG1490	D-aminoacyl-tRNA deacylase activity
AUC63_01673	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AUC63_01674	COG0587	DNA-directed DNA polymerase activity
AUC63_01676	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AUC63_01677	COG0488	(ABC) transporter
AUC63_01678	COG0617	tRNA 3'-terminal CCA addition
AUC63_01682	COG1266	CAAX protease self-immunity
AUC63_01683	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AUC63_01685	COG0004	ammonium transporteR
AUC63_01687	COG5263	repeat protein
AUC63_01687	COG0366	Alpha amylase catalytic
AUC63_01688	COG1316	TRANSCRIPTIONal
AUC63_01691	COG1216	Glycosyl transferase, family 2
AUC63_01694	COG1216	Glycosyl transferase, family 2
AUC63_01696	COG0438	transferase activity, transferring glycosyl groups
AUC63_01697	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AUC63_01698	COG0489	protein tyrosine kinase activity
AUC63_01701	COG0233	cytoplasmic translational termination
AUC63_01703	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AUC63_01704	COG0052	Belongs to the universal ribosomal protein uS2 family
AUC63_01705	COG2827	Endonuclease containing a URI domain
AUC63_01706	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AUC63_01707	COG0204	Acyl-transferase
AUC63_01708	COG0791	NLP P60 protein
AUC63_01708	COG3883	PFAM NLP P60 protein
AUC63_01711	COG3763	UPF0154 protein
AUC63_01712	COG4224	UPF0291 protein
AUC63_01713	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AUC63_01717	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AUC63_01717	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AUC63_01718	COG1234	tRNA 3'-trailer cleavage
AUC63_01721	COG0484	heat shock protein binding
AUC63_01722	COG0443	Heat shock 70 kDa protein
AUC63_01724	COG1420	regulation of RNA biosynthetic process
AUC63_01730	COG1216	Glycosyl transferase, family 2
AUC63_01732	COG0463	Glycosyl transferase, family 2
AUC63_01734	COG1705	Flagellar rod assembly protein muramidase FlgJ
AUC63_01737	COG0562	UDP-galactopyranose mutase
AUC63_01742	COG0024	Methionine aminopeptidase
AUC63_01747	COG2801	Transposase and inactivated derivatives
AUC63_01757	COG2309	aminopeptidase activity
AUC63_01760	COG0564	pseudouridine synthase activity
AUC63_01761	COG1278	Cold shock
AUC63_01763	COG2814	Major facilitator Superfamily
AUC63_01764	COG0741	lytic transglycosylase activity
AUC63_01765	COG1072	(Pantothenic acid kinase))
AUC63_01766	COG3973	AAA domain
AUC63_01768	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AUC63_01769	COG1058	Belongs to the CinA family
AUC63_01769	COG1546	Belongs to the CinA family
AUC63_01770	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AUC63_01771	COG1426	Protein conserved in bacteria
AUC63_01772	COG0612	Peptidase, M16
AUC63_01773	COG0612	Peptidase, M16
AUC63_01776	COG0028	Belongs to the TPP enzyme family
AUC63_01780	COG4717	serine-type aminopeptidase activity
AUC63_01783	COG3679	Belongs to the UPF0342 family
AUC63_01784	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AUC63_01785	COG1438	arginine binding
AUC63_01790	COG1959	2 iron, 2 sulfur cluster binding
AUC63_01794	COG0018	arginyl-trna synthetase
AUC63_01797	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AUC63_01799	COG1121	(ABC) transporter
AUC63_01803	COG1597	lipid kinase activity
AUC63_01804	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AUC63_01805	COG0154	amidase activity
AUC63_01806	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AUC63_01807	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AUC63_01807	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AUC63_01809	COG2936	dipeptidyl-peptidase activity
AUC63_01812	COG1695	Transcriptional regulator
AUC63_01814	COG1914	H( )-stimulated, divalent metal cation uptake system
AUC63_01818	COG0667	Aldo Keto reductase
AUC63_01819	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AUC63_01820	COG4721	ABC-type cobalt transport system, permease component
AUC63_01821	COG1122	ATPase activity
AUC63_01824	COG0758	DNA mediated transformation
AUC63_01827	COG0710	3-dehydroquinate dehydratase activity
AUC63_01828	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AUC63_01829	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AUC63_01830	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AUC63_01831	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AUC63_01832	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AUC63_01833	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AUC63_01836	COG4684	Psort location CytoplasmicMembrane, score
AUC63_01837	COG0436	Aminotransferase
AUC63_01842	COG2801	Transposase and inactivated derivatives
AUC63_01845	COG1783	phage Terminase large subunit
AUC63_01876	COG1396	sequence-specific DNA binding
AUC63_01883	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AUC63_01884	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AUC63_01885	COG0436	Aminotransferase
AUC63_01886	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AUC63_01887	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AUC63_01889	COG2171	N-acyltransferase activity
AUC63_01891	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AUC63_01892	COG0527	aspartate kinase activity
AUC63_01894	COG1609	Transcriptional regulator
AUC63_01895	COG0083	homoserine kinase activity
AUC63_01898	COG1321	iron dependent repressor
AUC63_01899	COG3764	Sortase (surface protein transpeptidase)
AUC63_01903	COG0513	Belongs to the DEAD box helicase family
AUC63_01904	COG0673	inositol 2-dehydrogenase activity
AUC63_01905	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AUC63_01907	COG0501	Belongs to the peptidase M48B family
AUC63_01908	COG1704	LemA family
AUC63_01910	COG4115	mRNA cleavage
AUC63_01911	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AUC63_01914	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AUC63_01916	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AUC63_01917	COG0439	Biotin carboxylase
AUC63_01920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AUC63_01921	COG1028	Short-chain dehydrogenase reductase Sdr
AUC63_01922	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AUC63_01923	COG2070	2-Nitropropane dioxygenase
AUC63_01924	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AUC63_01925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AUC63_01926	COG1846	Transcriptional regulator
AUC63_01927	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AUC63_01929	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AUC63_01930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AUC63_01932	COG0505	Belongs to the CarA family
AUC63_01934	COG0564	pseudouridine synthase activity
AUC63_01936	COG0328	RNA-DNA hybrid ribonuclease activity
AUC63_01938	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AUC63_01939	COG1113	amino acid transport
AUC63_01945	COG0656	L-ascorbic acid biosynthetic process
AUC63_01947	COG1012	belongs to the aldehyde dehydrogenase family
AUC63_01947	COG1454	alcohol dehydrogenase
AUC63_01948	COG0105	UTP biosynthetic process
AUC63_01950	COG0583	DNA-binding transcription factor activity
AUC63_01951	COG0126	phosphoglycerate kinase activity
AUC63_01961	COG0588	phosphoglycerate mutase activity
AUC63_01963	COG3716	PTS system mannose fructose sorbose family IID component
AUC63_01964	COG3715	PTS system
AUC63_01967	COG1397	ADP-ribosylglycohydrolase
AUC63_01979	COG1368	sulfuric ester hydrolase activity
AUC63_01982	COG0438	transferase activity, transferring glycosyl groups
AUC63_01983	COG0438	transferase activity, transferring glycosyl groups
AUC63_01984	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AUC63_01985	COG0284	orotidine-5'-phosphate decarboxylase activity
AUC63_01986	COG0167	dihydroorotate dehydrogenase activity
AUC63_01987	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AUC63_01988	COG0505	Belongs to the CarA family
AUC63_01989	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AUC63_01990	COG0540	Belongs to the ATCase OTCase family
AUC63_01995	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AUC63_01996	COG4856	YbbR-like protein
AUC63_01999	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AUC63_02002	COG0802	atpase or kinase
AUC63_02003	COG0280	phosphate acetyltransferase
AUC63_02004	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AUC63_02006	COG2076	Multidrug Resistance protein
AUC63_02007	COG2076	Multidrug Resistance protein
AUC63_02008	COG1126	abc transporter atp-binding protein
AUC63_02009	COG0765	amino acid transport
AUC63_02010	COG2814	Major facilitator Superfamily
AUC63_02013	COG0557	exoribonuclease II activity
AUC63_02016	COG0154	amidase activity
AUC63_02020	COG0149	triose-phosphate isomerase activity
AUC63_02021	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AUC63_02022	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AUC63_02024	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AUC63_02025	COG0492	ferredoxin-NADP+ reductase activity
AUC63_02030	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AUC63_02031	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AUC63_02032	COG1950	PFAM Membrane protein of
AUC63_02034	COG0589	response to stress
AUC63_02036	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AUC63_02038	COG1177	transmembrane transport
AUC63_02039	COG1176	ABC-type spermidine putrescine transport system, permease component I
AUC63_02040	COG3842	ATPase activity
AUC63_02042	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AUC63_02043	COG0049	tRNA binding
AUC63_02044	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AUC63_02046	COG4608	Belongs to the ABC transporter superfamily
AUC63_02047	COG0444	Belongs to the ABC transporter superfamily
AUC63_02048	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AUC63_02049	COG0601	transmembrane transport
AUC63_02051	COG0460	homoserine dehydrogenase
AUC63_02052	COG0626	cystathionine gamma-synthase activity
AUC63_02053	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AUC63_02056	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AUC63_02057	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AUC63_02060	COG1302	Protein conserved in bacteria
AUC63_02061	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AUC63_02063	COG2017	converts alpha-aldose to the beta-anomer
AUC63_02065	COG4975	Glucose uptake
AUC63_02066	COG5002	protein histidine kinase activity
AUC63_02066	COG3850	Histidine kinase
AUC63_02067	COG0745	RESPONSE REGULATOR receiver
AUC63_02068	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AUC63_02069	COG0402	S-adenosylhomocysteine deaminase activity
AUC63_02070	COG0673	inositol 2-dehydrogenase activity
AUC63_02071	COG0741	lytic transglycosylase activity
AUC63_02075	COG0668	transmembrane transport
AUC63_02077	COG1126	abc transporter atp-binding protein
AUC63_02078	COG0765	amino acid transport
AUC63_02086	COG0516	GMP reductase activity
AUC63_02100	COG2801	Transposase and inactivated derivatives
AUC63_02103	COG0494	nUDIX hydrolase
AUC63_02110	COG0738	Major facilitator superfamily
AUC63_02111	COG1869	D-ribose catabolic process
AUC63_02112	COG1609	Transcriptional regulator
AUC63_02116	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AUC63_02119	COG1609	Transcriptional regulator
AUC63_02124	COG2223	nitrite transmembrane transporter activity
AUC63_02126	COG0318	PFAM AMP-dependent synthetase and ligase
AUC63_02128	COG1116	anion transmembrane transporter activity
AUC63_02129	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AUC63_02131	COG0285	dihydrofolate synthase activity
AUC63_02132	COG0302	gtp cyclohydrolase
AUC63_02133	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AUC63_02133	COG0302	gtp cyclohydrolase
AUC63_02143	COG0561	phosphatase activity
AUC63_02146	COG4946	Tricorn protease homolog
AUC63_02146	COG1506	peptidase
AUC63_02146	COG0823	Involved in the tonB-independent uptake of proteins
AUC63_02147	COG1464	Belongs to the NlpA lipoprotein family
AUC63_02149	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AUC63_02150	COG0800	Aldolase
AUC63_02151	COG1904	glucuronate isomerase
AUC63_02152	COG1312	Catalyzes the dehydration of D-mannonate
AUC63_02153	COG0246	Mannitol dehydrogenase
AUC63_02156	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AUC63_02159	COG1609	Transcriptional regulator
AUC63_02165	COG0577	efflux transmembrane transporter activity
AUC63_02166	COG1136	(ABC) transporter
AUC63_02167	COG3759	membrane
AUC63_02172	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AUC63_02173	COG2235	arginine
AUC63_02175	COG2217	Heavy metal translocating P-type atpase
AUC63_02185	COG0438	transferase activity, transferring glycosyl groups
AUC63_02194	COG2814	Major facilitator Superfamily
AUC63_02195	COG2217	Heavy metal translocating P-type atpase
AUC63_02199	COG1309	transcriptional regulator
AUC63_02203	COG3711	transcriptional antiterminator
AUC63_02204	COG2723	6-phospho-beta-galactosidase activity
AUC63_02205	COG1940	carbohydrate kinase activity
AUC63_02210	COG2183	response to ionizing radiation
AUC63_02213	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AUC63_02214	COG1040	competence protein
AUC63_02215	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AUC63_02216	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import