locus-tag	class	description
AUC65_00009	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AUC65_00013	COG1368	sulfuric ester hydrolase activity
AUC65_00014	COG2153	protein acetylation
AUC65_00017	COG0187	DNA topoisomerase II activity
AUC65_00018	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AUC65_00019	COG2501	S4 domain
AUC65_00020	COG0592	DNA-directed DNA polymerase activity
AUC65_00021	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AUC65_00022	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AUC65_00023	COG0594	ribonuclease P activity
AUC65_00024	COG0706	membrane insertase activity
AUC65_00026	COG1120	ATPase activity
AUC65_00028	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AUC65_00031	COG0569	domain protein
AUC65_00032	COG1113	amino acid transport
AUC65_00036	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AUC65_00038	COG0446	pyridine nucleotide-disulphide oxidoreductase
AUC65_00040	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AUC65_00041	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AUC65_00043	COG1136	(ABC) transporter
AUC65_00044	COG0577	efflux transmembrane transporter activity
AUC65_00045	COG1033	growth of symbiont in host cell
AUC65_00045	COG2409	Drug exporters of the RND superfamily
AUC65_00046	COG0561	phosphatase activity
AUC65_00048	COG0328	RNA-DNA hybrid ribonuclease activity
AUC65_00052	COG3152	Membrane
AUC65_00053	COG2252	PERMEase
AUC65_00061	COG1881	PFAM PEBP family protein
AUC65_00075	COG1476	TRANSCRIPTIONal
AUC65_00080	COG0517	IMP dehydrogenase activity
AUC65_00080	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AUC65_00081	COG2723	6-phospho-beta-galactosidase activity
AUC65_00085	COG0697	spore germination
AUC65_00088	COG1744	ABC transporter substrate-binding protein PnrA-like
AUC65_00089	COG0137	argininosuccinate synthase activity
AUC65_00090	COG0165	Argininosuccinate lyase
AUC65_00091	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AUC65_00092	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AUC65_00094	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AUC65_00095	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AUC65_00096	COG0505	Belongs to the CarA family
AUC65_00097	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AUC65_00101	COG1131	(ABC) transporter
AUC65_00106	COG0789	Transcriptional regulator
AUC65_00109	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AUC65_00111	COG0697	spore germination
AUC65_00112	COG1744	ABC transporter substrate-binding protein PnrA-like
AUC65_00116	COG1846	Transcriptional regulator
AUC65_00117	COG1132	(ABC) transporter
AUC65_00119	COG0656	L-ascorbic acid biosynthetic process
AUC65_00121	COG4619	ABC transporter
AUC65_00122	COG0390	transport system, permease component
AUC65_00124	COG1131	(ABC) transporter
AUC65_00126	COG1126	abc transporter atp-binding protein
AUC65_00127	COG0765	amino acid transport
AUC65_00129	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AUC65_00130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AUC65_00131	COG1254	Belongs to the acylphosphatase family
AUC65_00133	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AUC65_00133	COG0392	lysyltransferase activity
AUC65_00135	COG0628	permease
AUC65_00141	COG1113	amino acid transport
AUC65_00146	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AUC65_00149	COG2855	membrane
AUC65_00150	COG3620	sequence-specific DNA binding
AUC65_00152	COG2855	membrane
AUC65_00153	COG0583	DNA-binding transcription factor activity
AUC65_00155	COG2070	2-Nitropropane dioxygenase
AUC65_00158	COG1228	amidohydrolase
AUC65_00159	COG0531	amino acid
AUC65_00161	COG3223	Belongs to the PsiE family
AUC65_00163	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AUC65_00165	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AUC65_00167	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AUC65_00168	COG4166	transmembrane transport
AUC65_00169	COG2267	carboxylic ester hydrolase activity
AUC65_00171	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AUC65_00174	COG0477	Major facilitator Superfamily
AUC65_00175	COG4975	Glucose uptake
AUC65_00177	COG0531	amino acid
AUC65_00178	COG1113	amino acid transport
AUC65_00179	COG0531	amino acid
AUC65_00180	COG0252	asparaginase activity
AUC65_00181	COG4443	Transcriptional Coactivator p15 (PC4)
AUC65_00183	COG2226	methyltransferase
AUC65_00184	COG1335	isochorismatase
AUC65_00185	COG2050	protein possibly involved in aromatic compounds catabolism
AUC65_00186	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AUC65_00187	COG0318	PFAM AMP-dependent synthetase and ligase
AUC65_00190	COG0745	RESPONSE REGULATOR receiver
AUC65_00191	COG5002	protein histidine kinase activity
AUC65_00199	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AUC65_00200	COG1194	a g-specific adenine glycosylase
AUC65_00202	COG0357	Ribosomal RNA small subunit methyltransferase G
AUC65_00203	COG1192	Involved in chromosome partitioning
AUC65_00204	COG1475	DNA binding
AUC65_00205	COG4481	Protein conserved in bacteria
AUC65_00206	COG0012	GTP binding
AUC65_00208	COG0745	RESPONSE REGULATOR receiver
AUC65_00210	COG1686	Belongs to the peptidase S11 family
AUC65_00220	COG3104	oligopeptide transport
AUC65_00221	COG0477	Major facilitator Superfamily
AUC65_00222	COG4975	Glucose uptake
AUC65_00231	COG3091	SprT-like family
AUC65_00232	COG2755	lipolytic protein G-D-S-L family
AUC65_00232	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AUC65_00235	COG1846	Transcriptional regulator
AUC65_00237	COG1121	(ABC) transporter
AUC65_00238	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AUC65_00239	COG0488	(ABC) transporter
AUC65_00240	COG0534	Mate efflux family protein
AUC65_00243	COG3940	Belongs to the glycosyl hydrolase 43 family
AUC65_00248	COG2160	L-arabinose isomerase activity
AUC65_00249	COG0656	L-ascorbic acid biosynthetic process
AUC65_00256	COG0765	amino acid transport
AUC65_00264	COG1215	transferase activity, transferring glycosyl groups
AUC65_00265	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AUC65_00266	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AUC65_00269	COG1418	mRNA catabolic process
AUC65_00270	COG2814	Major facilitator Superfamily
AUC65_00271	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AUC65_00272	COG2188	Transcriptional regulator
AUC65_00273	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AUC65_00276	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AUC65_00276	COG0463	Glycosyl transferase, family 2
AUC65_00280	COG1442	glycosyl transferase family 8
AUC65_00280	COG1216	Glycosyl transferase, family 2
AUC65_00281	COG1215	transferase activity, transferring glycosyl groups
AUC65_00282	COG2801	Transposase and inactivated derivatives
AUC65_00285	COG5039	Polysaccharide pyruvyl transferase
AUC65_00293	COG3590	peptidase
AUC65_00294	COG1012	belongs to the aldehyde dehydrogenase family
AUC65_00294	COG1454	alcohol dehydrogenase
AUC65_00296	COG0708	Exodeoxyribonuclease III
AUC65_00300	COG0588	phosphoglycerate mutase activity
AUC65_00304	COG1132	(ABC) transporter
AUC65_00305	COG1132	(ABC) transporter
AUC65_00310	COG0110	maltose O-acetyltransferase activity
AUC65_00312	COG1482	cell wall glycoprotein biosynthetic process
AUC65_00313	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AUC65_00314	COG3442	glutamine amidotransferase
AUC65_00316	COG1435	thymidine kinase activity
AUC65_00317	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AUC65_00318	COG2890	protein-(glutamine-N5) methyltransferase activity
AUC65_00319	COG0009	L-threonylcarbamoyladenylate synthase
AUC65_00320	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AUC65_00321	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AUC65_00322	COG0702	epimerase
AUC65_00324	COG2233	PERMEase
AUC65_00325	COG0356	it plays a direct role in the translocation of protons across the membrane
AUC65_00326	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AUC65_00327	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AUC65_00328	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AUC65_00329	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AUC65_00330	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AUC65_00331	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AUC65_00332	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AUC65_00333	COG1876	peptidase activity
AUC65_00334	COG1428	Deoxynucleoside kinase
AUC65_00335	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AUC65_00340	COG4463	regulation of RNA biosynthetic process
AUC65_00341	COG0542	response to heat
AUC65_00342	COG0085	RNA polymerase activity
AUC65_00346	COG1979	alcohol dehydrogenase
AUC65_00350	COG1309	transcriptional regulator
AUC65_00351	COG0500	methyltransferase
AUC65_00360	COG3620	sequence-specific DNA binding
AUC65_00362	COG2807	transmembrane transport
AUC65_00364	COG2813	Specifically methylates the guanine in position
AUC65_00365	COG0590	tRNA wobble adenosine to inosine editing
AUC65_00366	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AUC65_00371	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AUC65_00372	COG3870	Protein conserved in bacteria
AUC65_00376	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AUC65_00377	COG1214	PFAM Peptidase M22, glycoprotease
AUC65_00378	COG0456	acetyltransferase
AUC65_00380	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AUC65_00381	COG0142	geranyltranstransferase activity
AUC65_00382	COG0051	transcription antitermination factor activity, RNA binding
AUC65_00383	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AUC65_00385	COG0089	rRNA binding
AUC65_00386	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AUC65_00387	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AUC65_00388	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AUC65_00389	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AUC65_00390	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AUC65_00391	COG0255	Belongs to the universal ribosomal protein uL29 family
AUC65_00393	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AUC65_00394	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AUC65_00395	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AUC65_00396	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AUC65_00397	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AUC65_00398	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AUC65_00399	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AUC65_00400	COG1841	ribosomal large subunit assembly
AUC65_00401	COG0200	Binds to the 23S rRNA
AUC65_00404	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AUC65_00405	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AUC65_00407	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AUC65_00408	COG0202	RNA polymerase activity
AUC65_00409	COG0203	ribosomal protein L17
AUC65_00414	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AUC65_00417	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AUC65_00422	COG0583	DNA-binding transcription factor activity
AUC65_00423	COG0114	fumarate hydratase activity
AUC65_00424	COG1053	succinate dehydrogenase
AUC65_00425	COG0471	metal ion transport
AUC65_00426	COG0039	L-malate dehydrogenase activity
AUC65_00427	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AUC65_00428	COG0215	cysteine-tRNA ligase activity
AUC65_00429	COG0626	cystathionine gamma-synthase activity
AUC65_00430	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AUC65_00431	COG1464	Belongs to the NlpA lipoprotein family
AUC65_00432	COG1854	S-ribosylhomocysteine lyase activity
AUC65_00433	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AUC65_00434	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AUC65_00437	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AUC65_00438	COG0250	Participates in transcription elongation, termination and antitermination
AUC65_00439	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AUC65_00440	COG0081	regulation of translation
AUC65_00441	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AUC65_00442	COG0222	ribosome binding
AUC65_00444	COG1121	(ABC) transporter
AUC65_00445	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AUC65_00446	COG0803	Belongs to the bacterial solute-binding protein 9 family
AUC65_00447	COG1252	NADH dehydrogenase
AUC65_00449	COG1122	ATPase activity
AUC65_00450	COG1122	ATPase activity
AUC65_00452	COG0101	tRNA pseudouridine synthase activity
AUC65_00453	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AUC65_00455	COG4221	oxidoreductase activity
AUC65_00458	COG0028	Belongs to the TPP enzyme family
AUC65_00461	COG1573	uracil-dna glycosylase
AUC65_00467	COG0671	phosphoesterase, PA-phosphatase related
AUC65_00469	COG2814	Major facilitator Superfamily
AUC65_00470	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AUC65_00472	COG1660	Displays ATPase and GTPase activities
AUC65_00473	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AUC65_00474	COG1481	regulation of sporulation
AUC65_00475	COG0740	serine-type endopeptidase activity
AUC65_00478	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AUC65_00478	COG1263	PTS System
AUC65_00480	COG1914	H( )-stimulated, divalent metal cation uptake system
AUC65_00484	COG0039	L-malate dehydrogenase activity
AUC65_00485	COG0028	Belongs to the TPP enzyme family
AUC65_00486	COG3527	Alpha-acetolactate decarboxylase
AUC65_00488	COG1388	LysM domain
AUC65_00488	COG3942	CHAP domain
AUC65_00489	COG0791	NLP P60 protein
AUC65_00491	COG0756	dUTP diphosphatase activity
AUC65_00493	COG4956	integral membrane protein (PIN domain superfamily)
AUC65_00495	COG0653	protein targeting
AUC65_00496	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AUC65_00500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AUC65_00502	COG1733	regulation of RNA biosynthetic process
AUC65_00503	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AUC65_00504	COG0072	phenylalanine-tRNA ligase activity
AUC65_00504	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AUC65_00505	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AUC65_00506	COG0514	ATP-dependent DNA helicase (RecQ)
AUC65_00507	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AUC65_00509	COG0768	penicillin binding
AUC65_00510	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AUC65_00513	COG1940	carbohydrate kinase activity
AUC65_00514	COG5632	N-Acetylmuramoyl-L-alanine amidase
AUC65_00514	COG3409	Peptidoglycan-binding domain 1 protein
AUC65_00515	COG3942	CHAP domain
AUC65_00519	COG0584	glycerophosphoryl diester phosphodiesterase
AUC65_00520	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AUC65_00521	COG0789	Transcriptional regulator
AUC65_00522	COG0174	glutamine synthetase
AUC65_00527	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AUC65_00528	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AUC65_00529	COG1472	Belongs to the glycosyl hydrolase 3 family
AUC65_00531	COG1132	(ABC) transporter
AUC65_00532	COG0778	Nitroreductase
AUC65_00533	COG1169	isochorismate synthase
AUC65_00534	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AUC65_00535	COG0596	Alpha beta hydrolase
AUC65_00536	COG4948	Mandelate Racemase Muconate Lactonizing
AUC65_00540	COG0737	Belongs to the 5'-nucleotidase family
AUC65_00541	COG4470	Protein conserved in bacteria
AUC65_00542	COG0647	UMP catabolic process
AUC65_00543	COG4166	transmembrane transport
AUC65_00544	COG0673	inositol 2-dehydrogenase activity
AUC65_00548	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AUC65_00549	COG0573	inorganic phosphate transmembrane transporter activity
AUC65_00550	COG0581	inorganic phosphate transmembrane transporter activity
AUC65_00551	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AUC65_00552	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AUC65_00553	COG0704	Plays a role in the regulation of phosphate uptake
AUC65_00554	COG2137	regulation of response to DNA damage stimulus
AUC65_00559	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AUC65_00561	COG5506	Protein of unknown function (DUF1694)
AUC65_00563	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AUC65_00585	COG1272	protein, Hemolysin III
AUC65_00592	COG0525	valine-tRNA ligase activity
AUC65_00594	COG0285	dihydrofolate synthase activity
AUC65_00598	COG0488	(ABC) transporter
AUC65_00599	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AUC65_00600	COG0459	protein refolding
AUC65_00601	COG0531	amino acid
AUC65_00603	COG1181	Belongs to the D-alanine--D-alanine ligase family
AUC65_00604	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AUC65_00605	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AUC65_00607	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AUC65_00608	COG1713	HD superfamily hydrolase involved in NAD metabolism
AUC65_00609	COG0799	negative regulation of ribosome biogenesis
AUC65_00610	COG2226	methyltransferase
AUC65_00611	COG1323	Belongs to the UPF0348 family
AUC65_00613	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AUC65_00614	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AUC65_00634	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AUC65_00636	COG0363	glucosamine-6-phosphate deaminase activity
AUC65_00637	COG0776	regulation of translation
AUC65_00639	COG0577	efflux transmembrane transporter activity
AUC65_00640	COG1136	(ABC) transporter
AUC65_00643	COG4720	Psort location CytoplasmicMembrane, score
AUC65_00644	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AUC65_00645	COG1570	exodeoxyribonuclease VII activity
AUC65_00647	COG0142	geranyltranstransferase activity
AUC65_00648	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AUC65_00649	COG1438	arginine binding
AUC65_00650	COG0497	DNA recombination
AUC65_00652	COG0194	GDP metabolic process
AUC65_00654	COG0586	Pfam SNARE associated Golgi protein
AUC65_00655	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AUC65_00656	COG1098	S1 RNA binding domain
AUC65_00679	COG4684	Psort location CytoplasmicMembrane, score
AUC65_00680	COG1271	oxidase subunit
AUC65_00681	COG1294	oxidase, subunit
AUC65_00682	COG4988	ABC transporter
AUC65_00683	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AUC65_00684	COG1388	LysM domain
AUC65_00684	COG1705	Flagellar rod assembly protein muramidase FlgJ
AUC65_00685	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AUC65_00689	COG0494	nUDIX hydrolase
AUC65_00691	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AUC65_00692	COG0346	lactoylglutathione lyase activity
AUC65_00693	COG0400	carboxylic ester hydrolase activity
AUC65_00695	COG0741	lytic transglycosylase activity
AUC65_00699	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AUC65_00700	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AUC65_00701	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AUC65_00703	COG4120	Belongs to the binding-protein-dependent transport system permease family
AUC65_00705	COG0038	chloride channel
AUC65_00706	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AUC65_00707	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AUC65_00708	COG1307	EDD domain protein, DegV family
AUC65_00709	COG2190	(PTS) system
AUC65_00709	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AUC65_00709	COG1263	PTS System
AUC65_00712	COG2003	Belongs to the UPF0758 family
AUC65_00713	COG1077	Cell shape determining protein MreB Mrl
AUC65_00714	COG1792	Involved in formation and maintenance of cell shape
AUC65_00715	COG3338	carbonate dehydratase activity
AUC65_00717	COG0765	amino acid transport
AUC65_00718	COG1126	abc transporter atp-binding protein
AUC65_00721	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AUC65_00722	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AUC65_00723	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AUC65_00726	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AUC65_00728	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AUC65_00729	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AUC65_00730	COG0138	bifunctional purine biosynthesis protein purh
AUC65_00731	COG0151	Belongs to the GarS family
AUC65_00732	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AUC65_00735	COG0446	pyridine nucleotide-disulphide oxidoreductase
AUC65_00738	COG0833	amino acid
AUC65_00740	COG2264	protein methyltransferase activity
AUC65_00741	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AUC65_00743	COG2001	Belongs to the MraZ family
AUC65_00744	COG0275	rRNA processing
AUC65_00747	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AUC65_00748	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AUC65_00749	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AUC65_00750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AUC65_00751	COG0849	cell division
AUC65_00753	COG1799	cell septum assembly
AUC65_00756	COG3599	regulation of cell shape
AUC65_00760	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AUC65_00761	COG0217	transcriptional regulatory protein
AUC65_00762	COG2252	PERMEase
AUC65_00763	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AUC65_00771	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AUC65_00772	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AUC65_00773	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AUC65_00774	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AUC65_00774	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AUC65_00775	COG0631	protein serine/threonine phosphatase activity
AUC65_00776	COG0515	serine threonine protein kinase
AUC65_00776	COG2815	serine threonine protein kinase
AUC65_00777	COG1162	GTPase activity
AUC65_00778	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AUC65_00780	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AUC65_00782	COG1461	Dihydroxyacetone kinase
AUC65_00785	COG0438	transferase activity, transferring glycosyl groups
AUC65_00787	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AUC65_00788	COG0416	fatty acid biosynthetic process
AUC65_00789	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AUC65_00790	COG0571	ribonuclease III activity
AUC65_00791	COG1196	nuclear chromosome segregation
AUC65_00792	COG0552	protein localization to endoplasmic reticulum
AUC65_00794	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AUC65_00798	COG0228	four-way junction DNA binding
AUC65_00802	COG0588	phosphoglycerate mutase activity
AUC65_00803	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AUC65_00804	COG0336	Belongs to the RNA methyltransferase TrmD family
AUC65_00805	COG0335	large ribosomal subunit rRNA binding
AUC65_00807	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AUC65_00808	COG1942	4-Oxalocrotonate Tautomerase
AUC65_00809	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AUC65_00811	COG1428	Deoxynucleoside kinase
AUC65_00812	COG1970	mechanosensitive ion channel activity
AUC65_00813	COG0561	phosphatase activity
AUC65_00826	COG3853	Toxic anion resistance protein (TelA)
AUC65_00827	COG1393	Belongs to the ArsC family
AUC65_00828	COG4862	establishment of competence for transformation
AUC65_00829	COG2723	6-phospho-beta-galactosidase activity
AUC65_00830	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AUC65_00831	COG1447	Phosphotransferase system cellobiose-specific component IIA
AUC65_00832	COG2723	6-phospho-beta-galactosidase activity
AUC65_00833	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AUC65_00835	COG1164	Oligoendopeptidase f
AUC65_00836	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AUC65_00839	COG1609	Transcriptional regulator
AUC65_00840	COG0006	proline dipeptidase activity
AUC65_00854	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AUC65_00855	COG3425	synthase
AUC65_00858	COG0860	N-Acetylmuramoyl-L-alanine amidase
AUC65_00859	COG0124	histidyl-tRNA synthetase
AUC65_00860	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AUC65_00862	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AUC65_00863	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AUC65_00864	COG1610	YqeY-like protein
AUC65_00865	COG1702	phosphate starvation-inducible protein PhoH
AUC65_00866	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AUC65_00867	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AUC65_00868	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AUC65_00869	COG1381	Involved in DNA repair and RecF pathway recombination
AUC65_00872	COG0752	glycyl-tRNA synthetase alpha subunit
AUC65_00873	COG0751	glycine-tRNA ligase activity
AUC65_00877	COG2706	6-phosphogluconolactonase activity
AUC65_00878	COG0628	permease
AUC65_00880	COG1674	ftsk spoiiie
AUC65_00882	COG4152	abc transporter atp-binding protein
AUC65_00883	COG1668	transmembrane transport
AUC65_00886	COG0322	excinuclease ABC activity
AUC65_00887	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AUC65_00888	COG1739	Uncharacterized protein family UPF0029
AUC65_00892	COG0517	IMP dehydrogenase activity
AUC65_00892	COG0516	GMP reductase activity
AUC65_00893	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AUC65_00894	COG0632	four-way junction helicase activity
AUC65_00895	COG2255	four-way junction helicase activity
AUC65_00896	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AUC65_00903	COG0343	queuine tRNA-ribosyltransferase activity
AUC65_00904	COG1862	Preprotein translocase
AUC65_00905	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AUC65_00906	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AUC65_00907	COG0513	Belongs to the DEAD box helicase family
AUC65_00909	COG1929	Belongs to the glycerate kinase type-1 family
AUC65_00910	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AUC65_00914	COG3906	Belongs to the UPF0473 family
AUC65_00916	COG0658	competence protein
AUC65_00916	COG2333	competence protein COMEC
AUC65_00917	COG1466	dna polymerase III delta subunit
AUC65_00918	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AUC65_00919	COG0268	Binds directly to 16S ribosomal RNA
AUC65_00924	COG0544	peptidyl-prolyl cis-trans isomerase activity
AUC65_00925	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AUC65_00926	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AUC65_00930	COG1193	negative regulation of DNA recombination
AUC65_00934	COG3118	belongs to the thioredoxin family
AUC65_00935	COG0187	DNA topoisomerase II activity
AUC65_00936	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AUC65_00937	COG3527	Alpha-acetolactate decarboxylase
AUC65_00939	COG1473	amidohydrolase
AUC65_00942	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AUC65_00946	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AUC65_00947	COG3201	nicotinamide mononucleotide transporter
AUC65_00955	COG0277	FAD linked oxidase domain protein
AUC65_00956	COG0277	FAD linked oxidase domain protein
AUC65_00957	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AUC65_00959	COG0604	alcohol dehydrogenase
AUC65_00959	COG3321	synthase
AUC65_00963	COG2801	Transposase and inactivated derivatives
AUC65_00972	COG2801	Transposase and inactivated derivatives
AUC65_00978	COG0277	FAD linked oxidase domain protein
AUC65_00979	COG0436	Aminotransferase
AUC65_00982	COG1464	Belongs to the NlpA lipoprotein family
AUC65_00985	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AUC65_00986	COG0351	phosphomethylpyrimidine kinase
AUC65_00987	COG0352	thiamine-phosphate diphosphorylase activity
AUC65_00992	COG1028	Short-chain dehydrogenase reductase Sdr
AUC65_00994	COG1940	carbohydrate kinase activity
AUC65_01011	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AUC65_01012	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AUC65_01015	COG2357	RelA SpoT domain protein
AUC65_01016	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AUC65_01017	COG0564	pseudouridine synthase activity
AUC65_01018	COG2239	Acts as a magnesium transporter
AUC65_01019	COG2814	Major facilitator Superfamily
AUC65_01024	COG0488	(ABC) transporter
AUC65_01031	COG0583	DNA-binding transcription factor activity
AUC65_01033	COG0656	L-ascorbic acid biosynthetic process
AUC65_01034	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AUC65_01036	COG1846	Transcriptional regulator
AUC65_01047	COG0384	phenazine biosynthesis protein PhzF
AUC65_01049	COG1621	beta-fructofuranosidase activity
AUC65_01050	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AUC65_01051	COG0287	Prephenate dehydrogenase
AUC65_01053	COG0738	Major facilitator superfamily
AUC65_01054	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AUC65_01061	COG1304	FMN binding
AUC65_01064	COG0779	Required for maturation of 30S ribosomal subunits
AUC65_01065	COG0195	Participates in both transcription termination and antitermination
AUC65_01066	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AUC65_01068	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AUC65_01069	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AUC65_01070	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AUC65_01071	COG1252	NADH dehydrogenase
AUC65_01073	COG0196	riboflavin kinase activity
AUC65_01075	COG3142	Participates in the control of copper homeostasis
AUC65_01078	COG2270	Major facilitator Superfamily
AUC65_01079	COG1307	EDD domain protein, DegV family
AUC65_01080	COG1307	EDD domain protein, DegV family
AUC65_01081	COG2755	lipolytic protein G-D-S-L family
AUC65_01083	COG4479	Belongs to the UPF0346 family
AUC65_01085	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AUC65_01086	COG0758	DNA mediated transformation
AUC65_01087	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AUC65_01088	COG4974	Belongs to the 'phage' integrase family
AUC65_01090	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AUC65_01091	COG1227	inorganic diphosphatase activity
AUC65_01094	COG3448	diguanylate cyclase activity
AUC65_01094	COG4175	Glycine betaine
AUC65_01097	COG0446	pyridine nucleotide-disulphide oxidoreductase
AUC65_01098	COG1464	Belongs to the NlpA lipoprotein family
AUC65_01099	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AUC65_01100	COG1597	lipid kinase activity
AUC65_01102	COG1011	Hydrolase
AUC65_01109	COG0242	peptide deformylase activity
AUC65_01110	COG4476	Belongs to the UPF0223 family
AUC65_01111	COG0483	inositol monophosphate 1-phosphatase activity
AUC65_01113	COG0772	Belongs to the SEDS family
AUC65_01114	COG4471	UPF0298 protein
AUC65_01115	COG0742	ribosomal rna small subunit methyltransferase
AUC65_01116	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AUC65_01117	COG3480	Lon protease (S16) C-terminal proteolytic domain
AUC65_01118	COG0477	Major facilitator Superfamily
AUC65_01120	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AUC65_01121	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AUC65_01122	COG0358	DNA primase activity
AUC65_01123	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AUC65_01129	COG0745	RESPONSE REGULATOR receiver
AUC65_01130	COG5002	protein histidine kinase activity
AUC65_01131	COG0572	uridine kinase
AUC65_01132	COG1363	Peptidase, m42
AUC65_01133	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AUC65_01135	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AUC65_01136	COG0670	Belongs to the BI1 family
AUC65_01137	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AUC65_01137	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AUC65_01138	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AUC65_01139	COG0237	dephospho-CoA kinase activity
AUC65_01141	COG1484	DNA-dependent DNA replication
AUC65_01144	COG0745	RESPONSE REGULATOR receiver
AUC65_01145	COG5002	protein histidine kinase activity
AUC65_01147	COG3942	CHAP domain
AUC65_01147	COG1705	Flagellar rod assembly protein muramidase FlgJ
AUC65_01149	COG0531	amino acid
AUC65_01152	COG0706	membrane insertase activity
AUC65_01153	COG1028	Short-chain dehydrogenase reductase Sdr
AUC65_01154	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AUC65_01156	COG1304	FMN binding
AUC65_01160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AUC65_01160	COG1199	ATP-dependent helicase activity
AUC65_01162	COG0017	Asparaginyl-tRNA synthetase
AUC65_01163	COG3935	DnaD domain protein
AUC65_01165	COG3331	DNA recombination
AUC65_01166	COG4474	Belongs to the UPF0398 family
AUC65_01167	COG3599	regulation of cell shape
AUC65_01169	COG0116	Belongs to the methyltransferase superfamily
AUC65_01171	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AUC65_01175	COG0556	nucleotide-excision repair
AUC65_01177	COG0439	Biotin carboxylase
AUC65_01178	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AUC65_01179	COG0825	malonyl-CoA metabolic process
AUC65_01180	COG3104	oligopeptide transport
AUC65_01181	COG0363	glucosamine-6-phosphate deaminase activity
AUC65_01183	COG0537	adenosine 5'-monophosphoramidase activity
AUC65_01184	COG1131	(ABC) transporter
AUC65_01186	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AUC65_01187	COG1719	4-vinyl reductase, 4VR
AUC65_01188	COG1397	ADP-ribosylglycohydrolase
AUC65_01193	COG0446	pyridine nucleotide-disulphide oxidoreductase
AUC65_01194	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
AUC65_01195	COG1349	DNA-binding transcription factor activity
AUC65_01196	COG1105	Belongs to the carbohydrate kinase PfkB family
AUC65_01197	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AUC65_01197	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AUC65_01197	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AUC65_01199	COG1609	Transcriptional regulator
AUC65_01201	COG0306	phosphate transporter
AUC65_01203	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AUC65_01205	COG2723	6-phospho-beta-galactosidase activity
AUC65_01209	COG0531	amino acid
AUC65_01211	COG0481	GTPase activity
AUC65_01217	COG1028	Short-chain dehydrogenase reductase Sdr
AUC65_01218	COG4708	membrane
AUC65_01220	COG0531	amino acid
AUC65_01221	COG4221	oxidoreductase activity
AUC65_01222	COG0583	DNA-binding transcription factor activity
AUC65_01223	COG0281	malic enzyme
AUC65_01225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AUC65_01229	COG1136	(ABC) transporter
AUC65_01230	COG0577	efflux transmembrane transporter activity
AUC65_01234	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AUC65_01235	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AUC65_01239	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AUC65_01241	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AUC65_01242	COG2384	SAM-dependent methyltransferase
AUC65_01243	COG0071	Belongs to the small heat shock protein (HSP20) family
AUC65_01244	COG0457	Tetratricopeptide repeat
AUC65_01253	COG0419	ATPase involved in DNA repair
AUC65_01254	COG0420	3'-5' exonuclease activity
AUC65_01256	COG2807	transmembrane transport
AUC65_01257	COG4720	Psort location CytoplasmicMembrane, score
AUC65_01258	COG0351	phosphomethylpyrimidine kinase
AUC65_01260	COG1160	GTP binding
AUC65_01261	COG0539	negative regulation of cytoplasmic translation
AUC65_01262	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AUC65_01264	COG0514	ATP-dependent DNA helicase (RecQ)
AUC65_01266	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AUC65_01269	COG1187	pseudouridine synthase activity
AUC65_01270	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AUC65_01271	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AUC65_01274	COG2996	Protein conserved in bacteria
AUC65_01276	COG0475	glutathione-regulated potassium exporter activity
AUC65_01278	COG1490	D-aminoacyl-tRNA deacylase activity
AUC65_01279	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AUC65_01280	COG0587	DNA-directed DNA polymerase activity
AUC65_01282	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AUC65_01283	COG0488	(ABC) transporter
AUC65_01284	COG0617	tRNA 3'-terminal CCA addition
AUC65_01288	COG1266	CAAX protease self-immunity
AUC65_01289	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AUC65_01291	COG0004	ammonium transporteR
AUC65_01293	COG5263	repeat protein
AUC65_01293	COG0366	Alpha amylase catalytic
AUC65_01294	COG1316	TRANSCRIPTIONal
AUC65_01297	COG1216	Glycosyl transferase, family 2
AUC65_01300	COG1216	Glycosyl transferase, family 2
AUC65_01302	COG0438	transferase activity, transferring glycosyl groups
AUC65_01303	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AUC65_01304	COG0489	protein tyrosine kinase activity
AUC65_01307	COG0233	cytoplasmic translational termination
AUC65_01309	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AUC65_01310	COG0052	Belongs to the universal ribosomal protein uS2 family
AUC65_01311	COG2827	Endonuclease containing a URI domain
AUC65_01312	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AUC65_01313	COG0204	Acyl-transferase
AUC65_01314	COG0791	NLP P60 protein
AUC65_01314	COG3883	PFAM NLP P60 protein
AUC65_01317	COG3763	UPF0154 protein
AUC65_01318	COG4224	UPF0291 protein
AUC65_01319	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AUC65_01323	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AUC65_01323	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AUC65_01324	COG1234	tRNA 3'-trailer cleavage
AUC65_01327	COG0484	heat shock protein binding
AUC65_01328	COG0443	Heat shock 70 kDa protein
AUC65_01330	COG1420	regulation of RNA biosynthetic process
AUC65_01336	COG1216	Glycosyl transferase, family 2
AUC65_01338	COG0463	Glycosyl transferase, family 2
AUC65_01340	COG1705	Flagellar rod assembly protein muramidase FlgJ
AUC65_01343	COG0562	UDP-galactopyranose mutase
AUC65_01348	COG0024	Methionine aminopeptidase
AUC65_01353	COG2801	Transposase and inactivated derivatives
AUC65_01363	COG2309	aminopeptidase activity
AUC65_01366	COG0564	pseudouridine synthase activity
AUC65_01367	COG1278	Cold shock
AUC65_01369	COG2814	Major facilitator Superfamily
AUC65_01370	COG0741	lytic transglycosylase activity
AUC65_01371	COG1072	(Pantothenic acid kinase))
AUC65_01372	COG3973	AAA domain
AUC65_01374	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AUC65_01375	COG1546	Belongs to the CinA family
AUC65_01375	COG1058	Belongs to the CinA family
AUC65_01376	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AUC65_01377	COG1426	Protein conserved in bacteria
AUC65_01378	COG0612	Peptidase, M16
AUC65_01379	COG0612	Peptidase, M16
AUC65_01382	COG0028	Belongs to the TPP enzyme family
AUC65_01386	COG4717	serine-type aminopeptidase activity
AUC65_01389	COG3679	Belongs to the UPF0342 family
AUC65_01390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AUC65_01391	COG1438	arginine binding
AUC65_01396	COG1959	2 iron, 2 sulfur cluster binding
AUC65_01400	COG0018	arginyl-trna synthetase
AUC65_01403	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AUC65_01405	COG1121	(ABC) transporter
AUC65_01409	COG1597	lipid kinase activity
AUC65_01410	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AUC65_01411	COG0154	amidase activity
AUC65_01412	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AUC65_01413	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AUC65_01413	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AUC65_01415	COG2936	dipeptidyl-peptidase activity
AUC65_01418	COG1695	Transcriptional regulator
AUC65_01420	COG1914	H( )-stimulated, divalent metal cation uptake system
AUC65_01424	COG0667	Aldo Keto reductase
AUC65_01425	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AUC65_01426	COG4721	ABC-type cobalt transport system, permease component
AUC65_01427	COG1122	ATPase activity
AUC65_01430	COG0758	DNA mediated transformation
AUC65_01434	COG0710	3-dehydroquinate dehydratase activity
AUC65_01435	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AUC65_01436	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AUC65_01437	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AUC65_01438	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AUC65_01439	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AUC65_01440	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AUC65_01443	COG4684	Psort location CytoplasmicMembrane, score
AUC65_01444	COG0436	Aminotransferase
AUC65_01449	COG2801	Transposase and inactivated derivatives
AUC65_01452	COG1783	phage Terminase large subunit
AUC65_01483	COG1396	sequence-specific DNA binding
AUC65_01490	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AUC65_01491	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AUC65_01492	COG0436	Aminotransferase
AUC65_01493	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AUC65_01494	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AUC65_01496	COG2171	N-acyltransferase activity
AUC65_01498	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AUC65_01499	COG0527	aspartate kinase activity
AUC65_01501	COG1609	Transcriptional regulator
AUC65_01502	COG0083	homoserine kinase activity
AUC65_01505	COG1321	iron dependent repressor
AUC65_01506	COG3764	Sortase (surface protein transpeptidase)
AUC65_01510	COG0513	Belongs to the DEAD box helicase family
AUC65_01511	COG0673	inositol 2-dehydrogenase activity
AUC65_01512	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AUC65_01514	COG0501	Belongs to the peptidase M48B family
AUC65_01515	COG1704	LemA family
AUC65_01517	COG4115	mRNA cleavage
AUC65_01518	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AUC65_01521	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AUC65_01523	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AUC65_01524	COG0439	Biotin carboxylase
AUC65_01527	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AUC65_01528	COG1028	Short-chain dehydrogenase reductase Sdr
AUC65_01529	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AUC65_01530	COG2070	2-Nitropropane dioxygenase
AUC65_01531	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AUC65_01532	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AUC65_01533	COG1846	Transcriptional regulator
AUC65_01534	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AUC65_01536	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AUC65_01537	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AUC65_01539	COG0505	Belongs to the CarA family
AUC65_01541	COG0564	pseudouridine synthase activity
AUC65_01543	COG0328	RNA-DNA hybrid ribonuclease activity
AUC65_01545	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AUC65_01546	COG1113	amino acid transport
AUC65_01552	COG0656	L-ascorbic acid biosynthetic process
AUC65_01554	COG1012	belongs to the aldehyde dehydrogenase family
AUC65_01554	COG1454	alcohol dehydrogenase
AUC65_01555	COG0105	UTP biosynthetic process
AUC65_01557	COG0583	DNA-binding transcription factor activity
AUC65_01558	COG0126	phosphoglycerate kinase activity
AUC65_01568	COG0588	phosphoglycerate mutase activity
AUC65_01570	COG3716	PTS system mannose fructose sorbose family IID component
AUC65_01571	COG3715	PTS system
AUC65_01574	COG1397	ADP-ribosylglycohydrolase
AUC65_01586	COG1368	sulfuric ester hydrolase activity
AUC65_01589	COG0438	transferase activity, transferring glycosyl groups
AUC65_01590	COG0438	transferase activity, transferring glycosyl groups
AUC65_01591	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AUC65_01592	COG0284	orotidine-5'-phosphate decarboxylase activity
AUC65_01593	COG0167	dihydroorotate dehydrogenase activity
AUC65_01594	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AUC65_01595	COG0505	Belongs to the CarA family
AUC65_01596	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AUC65_01597	COG0540	Belongs to the ATCase OTCase family
AUC65_01602	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AUC65_01603	COG4856	YbbR-like protein
AUC65_01606	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AUC65_01609	COG0802	atpase or kinase
AUC65_01610	COG0280	phosphate acetyltransferase
AUC65_01611	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AUC65_01613	COG2076	Multidrug Resistance protein
AUC65_01614	COG2076	Multidrug Resistance protein
AUC65_01615	COG1126	abc transporter atp-binding protein
AUC65_01616	COG0765	amino acid transport
AUC65_01617	COG2814	Major facilitator Superfamily
AUC65_01620	COG0557	exoribonuclease II activity
AUC65_01623	COG0154	amidase activity
AUC65_01627	COG0149	triose-phosphate isomerase activity
AUC65_01628	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AUC65_01629	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AUC65_01631	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AUC65_01632	COG0492	ferredoxin-NADP+ reductase activity
AUC65_01637	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AUC65_01638	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AUC65_01639	COG1950	PFAM Membrane protein of
AUC65_01641	COG0589	response to stress
AUC65_01643	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AUC65_01645	COG1177	transmembrane transport
AUC65_01646	COG1176	ABC-type spermidine putrescine transport system, permease component I
AUC65_01647	COG3842	ATPase activity
AUC65_01649	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AUC65_01650	COG0049	tRNA binding
AUC65_01651	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AUC65_01653	COG4608	Belongs to the ABC transporter superfamily
AUC65_01654	COG0444	Belongs to the ABC transporter superfamily
AUC65_01655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AUC65_01656	COG0601	transmembrane transport
AUC65_01658	COG0460	homoserine dehydrogenase
AUC65_01659	COG0626	cystathionine gamma-synthase activity
AUC65_01660	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AUC65_01663	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AUC65_01664	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AUC65_01667	COG1302	Protein conserved in bacteria
AUC65_01668	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AUC65_01670	COG2017	converts alpha-aldose to the beta-anomer
AUC65_01672	COG4975	Glucose uptake
AUC65_01673	COG5002	protein histidine kinase activity
AUC65_01673	COG3850	Histidine kinase
AUC65_01674	COG0745	RESPONSE REGULATOR receiver
AUC65_01675	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AUC65_01676	COG0402	S-adenosylhomocysteine deaminase activity
AUC65_01677	COG0673	inositol 2-dehydrogenase activity
AUC65_01678	COG0741	lytic transglycosylase activity
AUC65_01682	COG0668	transmembrane transport
AUC65_01684	COG1126	abc transporter atp-binding protein
AUC65_01685	COG0765	amino acid transport
AUC65_01693	COG0516	GMP reductase activity
AUC65_01707	COG2801	Transposase and inactivated derivatives
AUC65_01710	COG0494	nUDIX hydrolase
AUC65_01717	COG0738	Major facilitator superfamily
AUC65_01718	COG1869	D-ribose catabolic process
AUC65_01719	COG1609	Transcriptional regulator
AUC65_01723	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AUC65_01726	COG1609	Transcriptional regulator
AUC65_01731	COG2223	nitrite transmembrane transporter activity
AUC65_01733	COG0318	PFAM AMP-dependent synthetase and ligase
AUC65_01735	COG1116	anion transmembrane transporter activity
AUC65_01736	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AUC65_01738	COG0285	dihydrofolate synthase activity
AUC65_01739	COG0302	gtp cyclohydrolase
AUC65_01740	COG0302	gtp cyclohydrolase
AUC65_01740	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AUC65_01750	COG0561	phosphatase activity
AUC65_01753	COG0823	Involved in the tonB-independent uptake of proteins
AUC65_01753	COG1506	peptidase
AUC65_01753	COG4946	Tricorn protease homolog
AUC65_01754	COG1464	Belongs to the NlpA lipoprotein family
AUC65_01756	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AUC65_01757	COG0800	Aldolase
AUC65_01758	COG1904	glucuronate isomerase
AUC65_01759	COG1312	Catalyzes the dehydration of D-mannonate
AUC65_01760	COG0246	Mannitol dehydrogenase
AUC65_01763	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AUC65_01766	COG1609	Transcriptional regulator
AUC65_01772	COG0577	efflux transmembrane transporter activity
AUC65_01773	COG1136	(ABC) transporter
AUC65_01774	COG3759	membrane
AUC65_01779	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AUC65_01780	COG2235	arginine
AUC65_01782	COG2217	Heavy metal translocating P-type atpase
AUC65_01792	COG0438	transferase activity, transferring glycosyl groups
AUC65_01801	COG2814	Major facilitator Superfamily
AUC65_01802	COG2217	Heavy metal translocating P-type atpase
AUC65_01806	COG1309	transcriptional regulator
AUC65_01810	COG3711	transcriptional antiterminator
AUC65_01811	COG2723	6-phospho-beta-galactosidase activity
AUC65_01812	COG1940	carbohydrate kinase activity
AUC65_01817	COG2183	response to ionizing radiation
AUC65_01820	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AUC65_01821	COG1040	competence protein
AUC65_01822	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AUC65_01823	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AUC65_01838	COG2176	DNA-directed DNA polymerase activity
AUC65_01839	COG0442	prolyl-tRNA aminoacylation
AUC65_01840	COG0750	zinc metalloprotease
AUC65_01841	COG4589	Belongs to the CDS family
AUC65_01842	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AUC65_01843	COG0561	phosphatase activity
AUC65_01844	COG2246	polysaccharide biosynthetic process
AUC65_01849	COG1811	Na channel or pump
AUC65_01850	COG1979	alcohol dehydrogenase
AUC65_01852	COG1174	glycine betaine transport
AUC65_01854	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AUC65_01856	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AUC65_01857	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AUC65_01857	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AUC65_01858	COG0307	riboflavin synthase, alpha
AUC65_01860	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AUC65_01860	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AUC65_01861	COG2076	Multidrug Resistance protein
AUC65_01862	COG2076	Multidrug Resistance protein
AUC65_01864	COG1435	thymidine kinase activity
AUC65_01867	COG1307	EDD domain protein, DegV family
AUC65_01868	COG0656	L-ascorbic acid biosynthetic process
AUC65_01869	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AUC65_01870	COG2814	Major facilitator Superfamily
AUC65_01873	COG1228	amidohydrolase
AUC65_01874	COG4166	transmembrane transport
AUC65_01875	COG0604	alcohol dehydrogenase
AUC65_01885	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AUC65_01887	COG2252	PERMEase
AUC65_01889	COG0352	thiamine-phosphate diphosphorylase activity
AUC65_01890	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AUC65_01892	COG2814	Major facilitator Superfamily
AUC65_01893	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AUC65_01897	COG1136	(ABC) transporter
AUC65_01897	COG0577	efflux transmembrane transporter activity
AUC65_01899	COG0561	phosphatase activity
AUC65_01900	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AUC65_01900	COG2169	Transcriptional regulator
AUC65_01901	COG0561	phosphatase activity
AUC65_01905	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AUC65_01906	COG0772	Belongs to the SEDS family
AUC65_01908	COG1077	Cell shape determining protein MreB Mrl
AUC65_01909	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AUC65_01914	COG0446	pyridine nucleotide-disulphide oxidoreductase
AUC65_01916	COG0640	Transcriptional regulator
AUC65_01917	COG0628	permease
AUC65_01918	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AUC65_01922	COG0386	Belongs to the glutathione peroxidase family
AUC65_01923	COG0588	phosphoglycerate mutase activity
AUC65_01926	COG0492	ferredoxin-NADP+ reductase activity
AUC65_01929	COG1744	ABC transporter substrate-binding protein PnrA-like
AUC65_01932	COG2832	Protein of unknown function (DUF454)
AUC65_01937	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AUC65_01939	COG2814	Major facilitator Superfamily
AUC65_01940	COG0305	Participates in initiation and elongation during chromosome replication
AUC65_01941	COG0359	binds to the 23S rRNA
AUC65_01943	COG4608	Belongs to the ABC transporter superfamily
AUC65_01944	COG0444	Belongs to the ABC transporter superfamily
AUC65_01945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AUC65_01946	COG0601	transmembrane transport
AUC65_01947	COG4166	transmembrane transport
AUC65_01948	COG0765	amino acid transport
AUC65_01949	COG0765	amino acid transport
AUC65_01950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AUC65_01951	COG1126	abc transporter atp-binding protein
AUC65_01954	COG0194	GDP metabolic process
AUC65_01955	COG1268	BioY protein
AUC65_01956	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AUC65_01956	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AUC65_01961	COG2211	Major facilitator Superfamily
AUC65_01962	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AUC65_01965	COG3973	AAA domain
AUC65_01969	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AUC65_01971	COG1696	Membrane protein involved in D-alanine export
AUC65_01975	COG2337	Toxic component of a toxin-antitoxin (TA) module
AUC65_01978	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AUC65_01979	COG0504	CTP synthase activity
AUC65_01981	COG3343	RNA polymerase activity
AUC65_01982	COG0561	phosphatase activity
AUC65_01983	COG1078	dGTPase activity
AUC65_01985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AUC65_01986	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AUC65_01990	COG0745	RESPONSE REGULATOR receiver
AUC65_01996	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AUC65_01997	COG0629	single-stranded DNA binding
AUC65_01998	COG0360	Binds together with S18 to 16S ribosomal RNA
AUC65_02001	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AUC65_02003	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AUC65_02004	COG1051	belongs to the nudix hydrolase family
AUC65_02007	COG2814	Major facilitator Superfamily
AUC65_02008	COG1064	alcohol dehydrogenase
AUC65_02009	COG1074	ATP-dependent DNA helicase activity
AUC65_02010	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AUC65_02013	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AUC65_02014	COG0531	amino acid
AUC65_02016	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AUC65_02018	COG1902	pentaerythritol trinitrate reductase activity
AUC65_02019	COG0626	cystathionine gamma-synthase activity
AUC65_02023	COG2244	polysaccharide biosynthetic process
AUC65_02025	COG0438	transferase activity, transferring glycosyl groups
AUC65_02026	COG0495	leucyl-tRNA aminoacylation
AUC65_02027	COG0671	phosphoesterase, PA-phosphatase related
AUC65_02029	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AUC65_02034	COG2723	6-phospho-beta-galactosidase activity
AUC65_02038	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AUC65_02040	COG2801	Transposase and inactivated derivatives
AUC65_02042	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AUC65_02044	COG0024	Methionine aminopeptidase
AUC65_02046	COG1316	TRANSCRIPTIONal
AUC65_02048	COG2205	protein histidine kinase activity
AUC65_02049	COG0745	RESPONSE REGULATOR receiver
AUC65_02050	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AUC65_02053	COG2207	Transcriptional regulator
AUC65_02057	COG0308	aminopeptidase N
AUC65_02058	COG0833	amino acid
AUC65_02059	COG2040	homocysteine
AUC65_02060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AUC65_02061	COG0542	response to heat
AUC65_02064	COG0395	ABC-type sugar transport system, permease component
AUC65_02065	COG1175	transmembrane transport
AUC65_02066	COG3842	ATPase activity
AUC65_02088	COG0438	transferase activity, transferring glycosyl groups
AUC65_02094	COG2084	Dehydrogenase
AUC65_02095	COG1028	Short-chain dehydrogenase reductase Sdr
AUC65_02097	COG1620	l-lactate permease
AUC65_02098	COG4989	oxidoreductase activity
AUC65_02099	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AUC65_02100	COG2233	PERMEase
AUC65_02103	COG1956	GAF domain-containing protein
AUC65_02106	COG1132	(ABC) transporter
AUC65_02107	COG1132	(ABC) transporter
AUC65_02108	COG1132	(ABC) transporter
AUC65_02109	COG0747	negative chemotaxis
AUC65_02110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AUC65_02111	COG0601	transmembrane transport
AUC65_02112	COG4608	Belongs to the ABC transporter superfamily
AUC65_02113	COG0444	Belongs to the ABC transporter superfamily
AUC65_02114	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AUC65_02115	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AUC65_02116	COG2211	Major facilitator Superfamily
AUC65_02116	COG2190	(PTS) system
AUC65_02120	COG0436	Aminotransferase
AUC65_02122	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AUC65_02123	COG2723	6-phospho-beta-galactosidase activity
AUC65_02124	COG2723	6-phospho-beta-galactosidase activity
AUC65_02125	COG1447	Phosphotransferase system cellobiose-specific component IIA
AUC65_02126	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AUC65_02127	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AUC65_02130	COG1216	Glycosyl transferase, family 2
AUC65_02133	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AUC65_02142	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AUC65_02143	COG1737	Transcriptional regulator
AUC65_02145	COG0656	L-ascorbic acid biosynthetic process
AUC65_02146	COG2261	transglycosylase associated protein
AUC65_02159	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AUC65_02160	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AUC65_02163	COG0037	tRNA processing
AUC65_02165	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AUC65_02166	COG2244	polysaccharide biosynthetic process
AUC65_02167	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AUC65_02168	COG0193	aminoacyl-tRNA hydrolase activity
AUC65_02170	COG0058	SHG alpha-glucan phosphorylase activity
AUC65_02171	COG0297	glycogen (starch) synthase activity
AUC65_02172	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AUC65_02174	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AUC65_02176	COG1511	domain protein
AUC65_02176	COG1511	domain protein
AUC65_02177	COG1309	transcriptional regulator
AUC65_02180	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AUC65_02181	COG0477	Major facilitator Superfamily
AUC65_02184	COG0667	Aldo Keto reductase
AUC65_02186	COG2115	Belongs to the xylose isomerase family
AUC65_02188	COG2211	Major facilitator Superfamily
AUC65_02189	COG3507	Belongs to the glycosyl hydrolase 43 family
AUC65_02194	COG2818	Glycosylase
AUC65_02195	COG1968	undecaprenyl-diphosphatase activity
AUC65_02198	COG1695	Transcriptional regulator
AUC65_02199	COG1983	PspC domain protein
AUC65_02200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AUC65_02201	COG0737	Belongs to the 5'-nucleotidase family
AUC65_02204	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AUC65_02206	COG2723	6-phospho-beta-galactosidase activity
AUC65_02207	COG2723	6-phospho-beta-galactosidase activity
AUC65_02208	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AUC65_02208	COG1263	PTS System
AUC65_02209	COG1316	TRANSCRIPTIONal
AUC65_02210	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AUC65_02211	COG2131	deaminase
AUC65_02212	COG4466	Protein conserved in bacteria
AUC65_02213	COG1253	flavin adenine dinucleotide binding
AUC65_02214	COG1253	flavin adenine dinucleotide binding
AUC65_02215	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AUC65_02216	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AUC65_02217	COG0084	hydrolase, TatD family'
AUC65_02219	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AUC65_02219	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AUC65_02232	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AUC65_02242	COG1368	sulfuric ester hydrolase activity
AUC65_02243	COG1368	sulfuric ester hydrolase activity
AUC65_02248	COG2153	protein acetylation
AUC65_02251	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AUC65_02253	COG2801	Transposase and inactivated derivatives
AUC65_02254	COG2910	NAD(P)H-binding
AUC65_02255	COG1733	regulation of RNA biosynthetic process
AUC65_02256	COG2801	Transposase and inactivated derivatives
AUC65_02258	COG1573	uracil-dna glycosylase
AUC65_02259	COG2801	Transposase and inactivated derivatives
AUC65_02268	COG0783	Belongs to the Dps family
AUC65_02269	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein