locus-tag	class	description
IDM39_00025	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IDM39_00050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IDM39_00070	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IDM39_00145	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IDM39_00145	COG0551	DNA topoisomerase type I activity
IDM39_00165	COG1136	(ABC) transporter
IDM39_00210	COG2176	DNA-directed DNA polymerase activity
IDM39_00220	COG0640	Transcriptional regulator
IDM39_00225	COG3118	belongs to the thioredoxin family
IDM39_00230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IDM39_00240	COG0492	ferredoxin-NADP+ reductase activity
IDM39_00250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IDM39_00255	COG1136	(ABC) transporter
IDM39_00300	COG2176	DNA-directed DNA polymerase activity
IDM39_00310	COG0640	Transcriptional regulator
IDM39_00315	COG3118	belongs to the thioredoxin family
IDM39_00320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IDM39_00330	COG0492	ferredoxin-NADP+ reductase activity
IDM39_00355	COG1960	acyl-CoA dehydrogenase activity
IDM39_00360	COG2086	electron transfer activity
IDM39_00365	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IDM39_00395	COG5263	repeat protein
IDM39_00395	COG0366	Alpha amylase catalytic
IDM39_00425	COG1914	H( )-stimulated, divalent metal cation uptake system
IDM39_00435	COG4466	Protein conserved in bacteria
IDM39_00440	COG1253	flavin adenine dinucleotide binding
IDM39_00445	COG1253	flavin adenine dinucleotide binding
IDM39_00450	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IDM39_00455	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IDM39_00460	COG0084	hydrolase, TatD family'
IDM39_00470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IDM39_00470	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IDM39_00490	COG2826	transposase and inactivated derivatives, IS30 family
IDM39_00510	COG2801	Transposase and inactivated derivatives
IDM39_00545	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IDM39_00565	COG1368	sulfuric ester hydrolase activity
IDM39_00570	COG2153	protein acetylation
IDM39_00585	COG0187	DNA topoisomerase II activity
IDM39_00590	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IDM39_00595	COG2501	S4 domain
IDM39_00600	COG0592	DNA-directed DNA polymerase activity
IDM39_00605	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IDM39_00610	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IDM39_00615	COG0594	ribonuclease P activity
IDM39_00620	COG0706	membrane insertase activity
IDM39_00630	COG1120	ATPase activity
IDM39_00640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IDM39_00660	COG0569	domain protein
IDM39_00665	COG1113	amino acid transport
IDM39_00685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IDM39_00695	COG0446	pyridine nucleotide-disulphide oxidoreductase
IDM39_00705	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IDM39_00710	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IDM39_00720	COG1136	(ABC) transporter
IDM39_00725	COG0577	efflux transmembrane transporter activity
IDM39_00730	COG1033	growth of symbiont in host cell
IDM39_00730	COG2409	Drug exporters of the RND superfamily
IDM39_00735	COG0561	phosphatase activity
IDM39_00745	COG0328	RNA-DNA hybrid ribonuclease activity
IDM39_00765	COG3152	Membrane
IDM39_00770	COG2252	PERMEase
IDM39_00810	COG1881	PFAM PEBP family protein
IDM39_00830	COG1476	TRANSCRIPTIONal
IDM39_00865	COG2723	6-phospho-beta-galactosidase activity
IDM39_00885	COG0697	spore germination
IDM39_00895	COG2211	Major facilitator Superfamily
IDM39_00900	COG1874	Beta-galactosidase
IDM39_00915	COG0561	phosphatase activity
IDM39_00925	COG1744	ABC transporter substrate-binding protein PnrA-like
IDM39_00930	COG0137	argininosuccinate synthase activity
IDM39_00940	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IDM39_00945	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IDM39_00955	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IDM39_00965	COG0505	Belongs to the CarA family
IDM39_00970	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IDM39_00990	COG1131	(ABC) transporter
IDM39_01010	COG0789	Transcriptional regulator
IDM39_01025	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IDM39_01035	COG0697	spore germination
IDM39_01060	COG1846	Transcriptional regulator
IDM39_01075	COG0656	L-ascorbic acid biosynthetic process
IDM39_01085	COG4619	ABC transporter
IDM39_01090	COG0390	transport system, permease component
IDM39_01100	COG1131	(ABC) transporter
IDM39_01110	COG1126	abc transporter atp-binding protein
IDM39_01115	COG0765	amino acid transport
IDM39_01120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IDM39_01125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IDM39_01130	COG1254	Belongs to the acylphosphatase family
IDM39_01140	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IDM39_01140	COG0392	lysyltransferase activity
IDM39_01150	COG0628	permease
IDM39_01180	COG1113	amino acid transport
IDM39_01205	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IDM39_01210	COG0454	-acetyltransferase
IDM39_01210	COG0456	acetyltransferase
IDM39_01220	COG2855	membrane
IDM39_01225	COG3620	sequence-specific DNA binding
IDM39_01235	COG2855	membrane
IDM39_01240	COG0583	DNA-binding transcription factor activity
IDM39_01250	COG2070	2-Nitropropane dioxygenase
IDM39_01265	COG1228	amidohydrolase
IDM39_01280	COG3223	Belongs to the PsiE family
IDM39_01290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IDM39_01300	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IDM39_01310	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IDM39_01315	COG4166	transmembrane transport
IDM39_01320	COG2267	carboxylic ester hydrolase activity
IDM39_01330	COG1131	(ABC) transporter
IDM39_01350	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IDM39_01365	COG0477	Major facilitator Superfamily
IDM39_01370	COG4975	Glucose uptake
IDM39_01390	COG0531	amino acid
IDM39_01395	COG1113	amino acid transport
IDM39_01400	COG0531	amino acid
IDM39_01405	COG0252	asparaginase activity
IDM39_01410	COG4443	Transcriptional Coactivator p15 (PC4)
IDM39_01420	COG2226	methyltransferase
IDM39_01425	COG1335	isochorismatase
IDM39_01430	COG2050	protein possibly involved in aromatic compounds catabolism
IDM39_01435	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IDM39_01440	COG0318	PFAM AMP-dependent synthetase and ligase
IDM39_01460	COG0745	RESPONSE REGULATOR receiver
IDM39_01465	COG5002	protein histidine kinase activity
IDM39_01485	COG2801	Transposase and inactivated derivatives
IDM39_01515	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IDM39_01520	COG1194	a g-specific adenine glycosylase
IDM39_01530	COG0357	Ribosomal RNA small subunit methyltransferase G
IDM39_01535	COG1192	Involved in chromosome partitioning
IDM39_01540	COG1475	DNA binding
IDM39_01545	COG4481	Protein conserved in bacteria
IDM39_01550	COG0012	GTP binding
IDM39_01560	COG0745	RESPONSE REGULATOR receiver
IDM39_01570	COG1686	Belongs to the peptidase S11 family
IDM39_01625	COG3104	oligopeptide transport
IDM39_01630	COG0477	Major facilitator Superfamily
IDM39_01635	COG4975	Glucose uptake
IDM39_01680	COG3091	SprT-like family
IDM39_01685	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IDM39_01685	COG2755	lipolytic protein G-D-S-L family
IDM39_01690	COG1846	Transcriptional regulator
IDM39_01700	COG1121	(ABC) transporter
IDM39_01710	COG1373	ATPase (AAA superfamily
IDM39_01715	COG0488	(ABC) transporter
IDM39_01720	COG0534	Mate efflux family protein
IDM39_01735	COG3940	Belongs to the glycosyl hydrolase 43 family
IDM39_01755	COG2160	L-arabinose isomerase activity
IDM39_01760	COG0656	L-ascorbic acid biosynthetic process
IDM39_01790	COG0765	amino acid transport
IDM39_01835	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
IDM39_01840	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IDM39_01855	COG1418	mRNA catabolic process
IDM39_01860	COG2814	Major facilitator Superfamily
IDM39_01870	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IDM39_01875	COG2188	Transcriptional regulator
IDM39_01880	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
IDM39_01895	COG5039	Polysaccharide pyruvyl transferase
IDM39_01920	COG3944	biosynthesis protein
IDM39_01930	COG0438	transferase activity, transferring glycosyl groups
IDM39_01940	COG0438	transferase activity, transferring glycosyl groups
IDM39_01945	COG1216	Glycosyl transferase, family 2
IDM39_01950	COG1215	transferase activity, transferring glycosyl groups
IDM39_01955	COG0463	Glycosyl transferase, family 2
IDM39_01955	COG1216	Glycosyl transferase, family 2
IDM39_01975	COG5039	Polysaccharide pyruvyl transferase
IDM39_02025	COG3590	peptidase
IDM39_02030	COG1454	alcohol dehydrogenase
IDM39_02030	COG1012	belongs to the aldehyde dehydrogenase family
IDM39_02040	COG0708	Exodeoxyribonuclease III
IDM39_02060	COG0588	phosphoglycerate mutase activity
IDM39_02065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IDM39_02080	COG1132	(ABC) transporter
IDM39_02085	COG1132	(ABC) transporter
IDM39_02090	COG1373	ATPase (AAA superfamily
IDM39_02095	COG1373	ATPase (AAA superfamily
IDM39_02100	COG2801	Transposase and inactivated derivatives
IDM39_02110	COG1373	ATPase (AAA superfamily
IDM39_02145	COG0110	maltose O-acetyltransferase activity
IDM39_02155	COG1482	cell wall glycoprotein biosynthetic process
IDM39_02160	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IDM39_02165	COG3442	glutamine amidotransferase
IDM39_02175	COG1435	thymidine kinase activity
IDM39_02180	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IDM39_02185	COG2890	protein-(glutamine-N5) methyltransferase activity
IDM39_02190	COG0009	L-threonylcarbamoyladenylate synthase
IDM39_02195	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IDM39_02200	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IDM39_02205	COG0702	epimerase
IDM39_02215	COG2233	PERMEase
IDM39_02220	COG0356	it plays a direct role in the translocation of protons across the membrane
IDM39_02225	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IDM39_02230	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IDM39_02235	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IDM39_02240	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IDM39_02245	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IDM39_02250	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IDM39_02255	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IDM39_02260	COG1876	peptidase activity
IDM39_02265	COG1428	Deoxynucleoside kinase
IDM39_02270	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IDM39_02295	COG4463	regulation of RNA biosynthetic process
IDM39_02300	COG0542	response to heat
IDM39_02305	COG0085	RNA polymerase activity
IDM39_02325	COG1979	alcohol dehydrogenase
IDM39_02360	COG1309	transcriptional regulator
IDM39_02365	COG0500	methyltransferase
IDM39_02410	COG3620	sequence-specific DNA binding
IDM39_02430	COG2813	Specifically methylates the guanine in position
IDM39_02435	COG0590	tRNA wobble adenosine to inosine editing
IDM39_02445	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IDM39_02470	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IDM39_02475	COG3870	Protein conserved in bacteria
IDM39_02495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IDM39_02500	COG1214	PFAM Peptidase M22, glycoprotease
IDM39_02505	COG0456	acetyltransferase
IDM39_02515	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IDM39_02520	COG0142	geranyltranstransferase activity
IDM39_02525	COG0051	transcription antitermination factor activity, RNA binding
IDM39_02530	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IDM39_02540	COG0089	rRNA binding
IDM39_02545	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IDM39_02550	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IDM39_02555	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IDM39_02560	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IDM39_02565	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IDM39_02570	COG0255	Belongs to the universal ribosomal protein uL29 family
IDM39_02580	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IDM39_02585	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IDM39_02590	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IDM39_02595	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IDM39_02600	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IDM39_02605	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IDM39_02610	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IDM39_02615	COG1841	ribosomal large subunit assembly
IDM39_02620	COG0200	Binds to the 23S rRNA
IDM39_02635	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IDM39_02640	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IDM39_02645	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IDM39_02650	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IDM39_02655	COG0202	RNA polymerase activity
IDM39_02660	COG0203	ribosomal protein L17
IDM39_02685	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IDM39_02700	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IDM39_02725	COG0583	DNA-binding transcription factor activity
IDM39_02730	COG0114	fumarate hydratase activity
IDM39_02735	COG1053	succinate dehydrogenase
IDM39_02740	COG0471	metal ion transport
IDM39_02745	COG0039	L-malate dehydrogenase activity
IDM39_02750	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IDM39_02755	COG0215	cysteine-tRNA ligase activity
IDM39_02760	COG0626	cystathionine gamma-synthase activity
IDM39_02765	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IDM39_02770	COG1464	Belongs to the NlpA lipoprotein family
IDM39_02775	COG1854	S-ribosylhomocysteine lyase activity
IDM39_02780	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IDM39_02785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IDM39_02800	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IDM39_02805	COG0250	Participates in transcription elongation, termination and antitermination
IDM39_02810	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IDM39_02815	COG0081	regulation of translation
IDM39_02820	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IDM39_02825	COG0222	ribosome binding
IDM39_02835	COG1121	(ABC) transporter
IDM39_02840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IDM39_02845	COG0803	Belongs to the bacterial solute-binding protein 9 family
IDM39_02850	COG1252	NADH dehydrogenase
IDM39_02860	COG1122	ATPase activity
IDM39_02865	COG1122	ATPase activity
IDM39_02875	COG0101	tRNA pseudouridine synthase activity
IDM39_02880	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IDM39_02895	COG0028	Belongs to the TPP enzyme family
IDM39_02910	COG1573	uracil-dna glycosylase
IDM39_02935	COG0671	phosphoesterase, PA-phosphatase related
IDM39_02945	COG2814	Major facilitator Superfamily
IDM39_02950	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IDM39_02965	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IDM39_02970	COG1481	regulation of sporulation
IDM39_02975	COG0740	serine-type endopeptidase activity
IDM39_02990	COG1263	PTS System
IDM39_02990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IDM39_03000	COG1914	H( )-stimulated, divalent metal cation uptake system
IDM39_03020	COG0039	L-malate dehydrogenase activity
IDM39_03025	COG0028	Belongs to the TPP enzyme family
IDM39_03030	COG3527	Alpha-acetolactate decarboxylase
IDM39_03040	COG1388	LysM domain
IDM39_03040	COG3942	CHAP domain
IDM39_03045	COG0791	NLP P60 protein
IDM39_03055	COG0756	dUTP diphosphatase activity
IDM39_03065	COG4956	integral membrane protein (PIN domain superfamily)
IDM39_03070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IDM39_03075	COG0653	protein targeting
IDM39_03080	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IDM39_03095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IDM39_03105	COG1733	regulation of RNA biosynthetic process
IDM39_03110	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IDM39_03115	COG0072	phenylalanine-tRNA ligase activity
IDM39_03115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IDM39_03120	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IDM39_03125	COG0514	ATP-dependent DNA helicase (RecQ)
IDM39_03130	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IDM39_03140	COG0768	penicillin binding
IDM39_03145	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IDM39_03160	COG1940	carbohydrate kinase activity
IDM39_03170	COG3409	Peptidoglycan-binding domain 1 protein
IDM39_03170	COG5632	N-Acetylmuramoyl-L-alanine amidase
IDM39_03175	COG3942	CHAP domain
IDM39_03195	COG0584	glycerophosphoryl diester phosphodiesterase
IDM39_03200	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IDM39_03205	COG0789	Transcriptional regulator
IDM39_03210	COG0174	glutamine synthetase
IDM39_03240	COG2801	Transposase and inactivated derivatives
IDM39_03255	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IDM39_03260	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IDM39_03280	COG1132	(ABC) transporter
IDM39_03285	COG0778	Nitroreductase
IDM39_03290	COG1169	isochorismate synthase
IDM39_03295	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IDM39_03300	COG0596	Alpha beta hydrolase
IDM39_03305	COG4948	Mandelate Racemase Muconate Lactonizing
IDM39_03335	COG0737	Belongs to the 5'-nucleotidase family
IDM39_03340	COG4470	Protein conserved in bacteria
IDM39_03345	COG0647	UMP catabolic process
IDM39_03355	COG4166	transmembrane transport
IDM39_03360	COG0673	inositol 2-dehydrogenase activity
IDM39_03385	COG0573	inorganic phosphate transmembrane transporter activity
IDM39_03390	COG0581	inorganic phosphate transmembrane transporter activity
IDM39_03395	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IDM39_03400	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IDM39_03405	COG0704	Plays a role in the regulation of phosphate uptake
IDM39_03410	COG2137	regulation of response to DNA damage stimulus
IDM39_03445	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IDM39_03455	COG5506	Protein of unknown function (DUF1694)
IDM39_03465	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IDM39_03570	COG1272	protein, Hemolysin III
IDM39_03605	COG0525	valine-tRNA ligase activity
IDM39_03615	COG0285	dihydrofolate synthase activity
IDM39_03635	COG0488	(ABC) transporter
IDM39_03640	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IDM39_03645	COG0459	protein refolding
IDM39_03650	COG0531	amino acid
IDM39_03660	COG1181	Belongs to the D-alanine--D-alanine ligase family
IDM39_03665	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
IDM39_03670	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IDM39_03680	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IDM39_03685	COG1713	HD superfamily hydrolase involved in NAD metabolism
IDM39_03690	COG0799	negative regulation of ribosome biogenesis
IDM39_03695	COG2226	methyltransferase
IDM39_03700	COG1323	Belongs to the UPF0348 family
IDM39_03710	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IDM39_03715	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IDM39_03815	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IDM39_03825	COG0363	glucosamine-6-phosphate deaminase activity
IDM39_03830	COG0776	regulation of translation
IDM39_03840	COG0577	efflux transmembrane transporter activity
IDM39_03845	COG1136	(ABC) transporter
IDM39_03860	COG4720	Psort location CytoplasmicMembrane, score
IDM39_03865	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IDM39_03870	COG1570	exodeoxyribonuclease VII activity
IDM39_03880	COG0142	geranyltranstransferase activity
IDM39_03885	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
IDM39_03890	COG1438	arginine binding
IDM39_03895	COG0497	DNA recombination
IDM39_03905	COG0194	GDP metabolic process
IDM39_03915	COG0586	Pfam SNARE associated Golgi protein
IDM39_03920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IDM39_03925	COG1098	S1 RNA binding domain
IDM39_04035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IDM39_04040	COG4684	Psort location CytoplasmicMembrane, score
IDM39_04045	COG1271	oxidase subunit
IDM39_04050	COG1294	oxidase, subunit
IDM39_04055	COG4988	ABC transporter
IDM39_04060	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IDM39_04065	COG1388	LysM domain
IDM39_04065	COG1705	Flagellar rod assembly protein muramidase FlgJ
IDM39_04070	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IDM39_04085	COG1278	Cold shock
IDM39_04090	COG0494	nUDIX hydrolase
IDM39_04100	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IDM39_04105	COG0346	lactoylglutathione lyase activity
IDM39_04110	COG0400	carboxylic ester hydrolase activity
IDM39_04120	COG0741	lytic transglycosylase activity
IDM39_04140	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IDM39_04145	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IDM39_04150	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IDM39_04160	COG4120	Belongs to the binding-protein-dependent transport system permease family
IDM39_04170	COG0038	chloride channel
IDM39_04175	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IDM39_04180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IDM39_04185	COG1307	EDD domain protein, DegV family
IDM39_04190	COG1263	PTS System
IDM39_04190	COG2190	(PTS) system
IDM39_04190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IDM39_04210	COG1077	Cell shape determining protein MreB Mrl
IDM39_04225	COG3338	carbonate dehydratase activity
IDM39_04235	COG0765	amino acid transport
IDM39_04240	COG1126	abc transporter atp-binding protein
IDM39_04245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IDM39_04250	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IDM39_04250	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IDM39_04255	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IDM39_04260	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IDM39_04265	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IDM39_04280	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IDM39_04290	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IDM39_04295	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IDM39_04300	COG0138	bifunctional purine biosynthesis protein purh
IDM39_04305	COG0151	Belongs to the GarS family
IDM39_04310	COG2759	Belongs to the formate--tetrahydrofolate ligase family
IDM39_04325	COG0446	pyridine nucleotide-disulphide oxidoreductase
IDM39_04340	COG0833	amino acid
IDM39_04350	COG2264	protein methyltransferase activity
IDM39_04355	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IDM39_04375	COG2001	Belongs to the MraZ family
IDM39_04380	COG0275	rRNA processing
IDM39_04390	COG0768	penicillin binding
IDM39_04395	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IDM39_04400	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IDM39_04405	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IDM39_04410	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IDM39_04415	COG0849	cell division
IDM39_04425	COG1799	cell septum assembly
IDM39_04440	COG3599	regulation of cell shape
IDM39_04460	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IDM39_04465	COG0217	transcriptional regulatory protein
IDM39_04470	COG2252	PERMEase
IDM39_04520	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IDM39_04525	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IDM39_04530	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IDM39_04535	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IDM39_04535	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IDM39_04540	COG0631	protein serine/threonine phosphatase activity
IDM39_04545	COG0515	serine threonine protein kinase
IDM39_04545	COG2815	serine threonine protein kinase
IDM39_04550	COG1162	GTPase activity
IDM39_04555	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IDM39_04565	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IDM39_04575	COG1461	Dihydroxyacetone kinase
IDM39_04615	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IDM39_04620	COG0416	fatty acid biosynthetic process
IDM39_04625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IDM39_04630	COG0571	ribonuclease III activity
IDM39_04635	COG1196	nuclear chromosome segregation
IDM39_04640	COG0552	protein localization to endoplasmic reticulum
IDM39_04645	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IDM39_04650	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IDM39_04670	COG0228	four-way junction DNA binding
IDM39_04675	COG0582	viral genome integration into host DNA
IDM39_04690	COG1396	sequence-specific DNA binding
IDM39_04855	COG2801	Transposase and inactivated derivatives
IDM39_04875	COG1002	Type II restriction enzyme, methylase subunits
IDM39_04880	COG1061	Type III restriction enzyme res subunit
IDM39_04885	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IDM39_04890	COG2801	Transposase and inactivated derivatives
IDM39_04930	COG0588	phosphoglycerate mutase activity
IDM39_04935	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IDM39_04940	COG0336	Belongs to the RNA methyltransferase TrmD family
IDM39_04945	COG0335	large ribosomal subunit rRNA binding
IDM39_04955	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IDM39_04960	COG1942	4-Oxalocrotonate Tautomerase
IDM39_04965	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IDM39_04975	COG1428	Deoxynucleoside kinase
IDM39_04980	COG1970	mechanosensitive ion channel activity
IDM39_04985	COG0561	phosphatase activity
IDM39_05050	COG3853	Toxic anion resistance protein (TelA)
IDM39_05055	COG1393	Belongs to the ArsC family
IDM39_05060	COG4862	establishment of competence for transformation
IDM39_05065	COG2723	6-phospho-beta-galactosidase activity
IDM39_05070	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IDM39_05075	COG1447	Phosphotransferase system cellobiose-specific component IIA
IDM39_05080	COG2723	6-phospho-beta-galactosidase activity
IDM39_05085	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IDM39_05095	COG1164	Oligoendopeptidase f
IDM39_05100	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IDM39_05115	COG1609	Transcriptional regulator
IDM39_05120	COG0006	proline dipeptidase activity
IDM39_05200	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IDM39_05205	COG3425	synthase
IDM39_05220	COG0860	N-Acetylmuramoyl-L-alanine amidase
IDM39_05225	COG0124	histidyl-tRNA synthetase
IDM39_05230	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IDM39_05240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IDM39_05245	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IDM39_05250	COG1610	YqeY-like protein
IDM39_05255	COG1702	phosphate starvation-inducible protein PhoH
IDM39_05260	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IDM39_05265	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IDM39_05270	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IDM39_05275	COG1381	Involved in DNA repair and RecF pathway recombination
IDM39_05290	COG0752	glycyl-tRNA synthetase alpha subunit
IDM39_05295	COG0751	glycine-tRNA ligase activity
IDM39_05315	COG2706	6-phosphogluconolactonase activity
IDM39_05320	COG0628	permease
IDM39_05330	COG1674	ftsk spoiiie
IDM39_05340	COG4152	abc transporter atp-binding protein
IDM39_05345	COG1668	transmembrane transport
IDM39_05355	COG0322	excinuclease ABC activity
IDM39_05360	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IDM39_05365	COG1739	Uncharacterized protein family UPF0029
IDM39_05380	COG0516	GMP reductase activity
IDM39_05380	COG0517	IMP dehydrogenase activity
IDM39_05385	COG0516	GMP reductase activity
IDM39_05385	COG0517	IMP dehydrogenase activity
IDM39_05390	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IDM39_05395	COG0632	four-way junction helicase activity
IDM39_05400	COG2255	four-way junction helicase activity
IDM39_05405	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IDM39_05440	COG0343	queuine tRNA-ribosyltransferase activity
IDM39_05445	COG1862	Preprotein translocase
IDM39_05450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IDM39_05455	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IDM39_05460	COG0513	Belongs to the DEAD box helicase family
IDM39_05475	COG1929	Belongs to the glycerate kinase type-1 family
IDM39_05480	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IDM39_05500	COG3906	Belongs to the UPF0473 family
IDM39_05510	COG0658	competence protein
IDM39_05510	COG2333	competence protein COMEC
IDM39_05515	COG1466	dna polymerase III delta subunit
IDM39_05520	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IDM39_05525	COG0268	Binds directly to 16S ribosomal RNA
IDM39_05555	COG0544	peptidyl-prolyl cis-trans isomerase activity
IDM39_05560	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IDM39_05565	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IDM39_05585	COG1193	negative regulation of DNA recombination
IDM39_05605	COG3118	belongs to the thioredoxin family
IDM39_05610	COG0187	DNA topoisomerase II activity
IDM39_05615	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IDM39_05620	COG3527	Alpha-acetolactate decarboxylase
IDM39_05630	COG1473	amidohydrolase
IDM39_05645	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IDM39_05665	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IDM39_05670	COG3201	nicotinamide mononucleotide transporter
IDM39_05705	COG0028	Belongs to the TPP enzyme family
IDM39_05715	COG0277	FAD linked oxidase domain protein
IDM39_05720	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IDM39_05725	COG0248	Ppx GppA phosphatase
IDM39_05740	COG2801	Transposase and inactivated derivatives
IDM39_05775	COG0277	FAD linked oxidase domain protein
IDM39_05780	COG0436	Aminotransferase
IDM39_05795	COG1464	Belongs to the NlpA lipoprotein family
IDM39_05810	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IDM39_05820	COG0352	thiamine-phosphate diphosphorylase activity
IDM39_05840	COG1028	Short-chain dehydrogenase reductase Sdr
IDM39_05850	COG1940	carbohydrate kinase activity
IDM39_05935	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IDM39_05940	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IDM39_05960	COG5290	Psort location Cytoplasmic, score
IDM39_05970	COG2357	RelA SpoT domain protein
IDM39_05975	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IDM39_05980	COG0564	pseudouridine synthase activity
IDM39_05985	COG2239	Acts as a magnesium transporter
IDM39_05990	COG2814	Major facilitator Superfamily
IDM39_06015	COG0488	(ABC) transporter
IDM39_06060	COG0656	L-ascorbic acid biosynthetic process
IDM39_06065	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IDM39_06075	COG1846	Transcriptional regulator
IDM39_06080	COG0456	acetyltransferase
IDM39_06145	COG4684	Psort location CytoplasmicMembrane, score
IDM39_06155	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IDM39_06175	COG1942	4-Oxalocrotonate Tautomerase
IDM39_06200	COG0384	phenazine biosynthesis protein PhzF
IDM39_06210	COG1621	beta-fructofuranosidase activity
IDM39_06230	COG2409	Drug exporters of the RND superfamily
IDM39_06230	COG1033	growth of symbiont in host cell
IDM39_06245	COG0583	DNA-binding transcription factor activity
IDM39_06265	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IDM39_06270	COG0287	Prephenate dehydrogenase
IDM39_06280	COG0738	Major facilitator superfamily
IDM39_06285	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IDM39_06315	COG1304	FMN binding
IDM39_06330	COG0779	Required for maturation of 30S ribosomal subunits
IDM39_06335	COG0195	Participates in both transcription termination and antitermination
IDM39_06340	COG2740	Nucleic-acid-binding protein implicated in transcription termination
IDM39_06350	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IDM39_06355	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IDM39_06360	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IDM39_06365	COG1252	NADH dehydrogenase
IDM39_06375	COG0196	riboflavin kinase activity
IDM39_06380	COG1293	RNA-binding protein homologous to eukaryotic snRNP
IDM39_06385	COG3142	Participates in the control of copper homeostasis
IDM39_06400	COG2270	Major facilitator Superfamily
IDM39_06405	COG1307	EDD domain protein, DegV family
IDM39_06410	COG1307	EDD domain protein, DegV family
IDM39_06415	COG2755	lipolytic protein G-D-S-L family
IDM39_06425	COG4479	Belongs to the UPF0346 family
IDM39_06435	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IDM39_06440	COG0758	DNA mediated transformation
IDM39_06445	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IDM39_06450	COG4974	Belongs to the 'phage' integrase family
IDM39_06470	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IDM39_06490	COG3448	diguanylate cyclase activity
IDM39_06490	COG4175	Glycine betaine
IDM39_06505	COG0446	pyridine nucleotide-disulphide oxidoreductase
IDM39_06510	COG1464	Belongs to the NlpA lipoprotein family
IDM39_06515	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IDM39_06520	COG1597	lipid kinase activity
IDM39_06525	COG1011	Hydrolase
IDM39_06555	COG5503	Protein of unknown function (DUF1447)
IDM39_06570	COG0242	peptide deformylase activity
IDM39_06575	COG4476	Belongs to the UPF0223 family
IDM39_06580	COG0483	inositol monophosphate 1-phosphatase activity
IDM39_06585	COG1217	gtp-binding protein TYPA
IDM39_06590	COG0772	Belongs to the SEDS family
IDM39_06595	COG4471	UPF0298 protein
IDM39_06600	COG0742	ribosomal rna small subunit methyltransferase
IDM39_06605	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IDM39_06610	COG3480	Lon protease (S16) C-terminal proteolytic domain
IDM39_06615	COG0477	Major facilitator Superfamily
IDM39_06625	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
IDM39_06630	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IDM39_06695	COG2801	Transposase and inactivated derivatives
IDM39_06715	COG2017	converts alpha-aldose to the beta-anomer
IDM39_06720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IDM39_06735	COG2801	Transposase and inactivated derivatives
IDM39_06745	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IDM39_06750	COG0459	protein refolding
IDM39_06760	COG1134	teichoic acid transport
IDM39_06760	COG1388	LysM domain
IDM39_06790	COG0358	DNA primase activity
IDM39_06795	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IDM39_06825	COG0745	RESPONSE REGULATOR receiver
IDM39_06830	COG5002	protein histidine kinase activity
IDM39_06835	COG0572	uridine kinase
IDM39_06840	COG1363	Peptidase, m42
IDM39_06845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IDM39_06855	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IDM39_06860	COG0670	Belongs to the BI1 family
IDM39_06865	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IDM39_06865	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IDM39_06870	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IDM39_06875	COG0237	dephospho-CoA kinase activity
IDM39_06885	COG1484	DNA-dependent DNA replication
IDM39_06900	COG0745	RESPONSE REGULATOR receiver
IDM39_06905	COG5002	protein histidine kinase activity
IDM39_06915	COG3942	CHAP domain
IDM39_06915	COG1705	Flagellar rod assembly protein muramidase FlgJ
IDM39_06925	COG2801	Transposase and inactivated derivatives
IDM39_06950	COG0706	membrane insertase activity
IDM39_06955	COG1028	Short-chain dehydrogenase reductase Sdr
IDM39_06960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IDM39_06970	COG1304	FMN binding
IDM39_06990	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IDM39_06990	COG1199	ATP-dependent helicase activity
IDM39_07000	COG0017	Asparaginyl-tRNA synthetase
IDM39_07005	COG3935	DnaD domain protein
IDM39_07015	COG3331	DNA recombination
IDM39_07020	COG4474	Belongs to the UPF0398 family
IDM39_07025	COG3599	regulation of cell shape
IDM39_07035	COG0116	Belongs to the methyltransferase superfamily
IDM39_07045	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IDM39_07065	COG0556	nucleotide-excision repair
IDM39_07075	COG0439	Biotin carboxylase
IDM39_07080	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IDM39_07090	COG3104	oligopeptide transport
IDM39_07095	COG0363	glucosamine-6-phosphate deaminase activity
IDM39_07105	COG0537	adenosine 5'-monophosphoramidase activity
IDM39_07110	COG1131	(ABC) transporter
IDM39_07120	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IDM39_07125	COG1719	4-vinyl reductase, 4VR
IDM39_07130	COG1397	ADP-ribosylglycohydrolase
IDM39_07160	COG0446	pyridine nucleotide-disulphide oxidoreductase
IDM39_07165	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
IDM39_07170	COG1349	DNA-binding transcription factor activity
IDM39_07175	COG1105	Belongs to the carbohydrate kinase PfkB family
IDM39_07180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IDM39_07180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IDM39_07180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IDM39_07190	COG1609	Transcriptional regulator
IDM39_07200	COG0306	phosphate transporter
IDM39_07215	COG2723	6-phospho-beta-galactosidase activity
IDM39_07235	COG0531	amino acid
IDM39_07245	COG0481	GTPase activity
IDM39_07280	COG1028	Short-chain dehydrogenase reductase Sdr
IDM39_07285	COG4708	membrane
IDM39_07295	COG0531	amino acid
IDM39_07300	COG4221	oxidoreductase activity
IDM39_07305	COG0583	DNA-binding transcription factor activity
IDM39_07310	COG0281	malic enzyme
IDM39_07320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IDM39_07335	COG1136	(ABC) transporter
IDM39_07340	COG0577	efflux transmembrane transporter activity
IDM39_07350	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IDM39_07360	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IDM39_07365	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IDM39_07395	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IDM39_07400	COG2384	SAM-dependent methyltransferase
IDM39_07405	COG0071	Belongs to the small heat shock protein (HSP20) family
IDM39_07410	COG0457	Tetratricopeptide repeat
IDM39_07455	COG0419	ATPase involved in DNA repair
IDM39_07460	COG0420	3'-5' exonuclease activity
IDM39_07475	COG4720	Psort location CytoplasmicMembrane, score
IDM39_07480	COG0351	phosphomethylpyrimidine kinase
IDM39_07490	COG1160	GTP binding
IDM39_07495	COG0539	negative regulation of cytoplasmic translation
IDM39_07500	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IDM39_07510	COG0514	ATP-dependent DNA helicase (RecQ)
IDM39_07520	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IDM39_07535	COG1187	pseudouridine synthase activity
IDM39_07540	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IDM39_07545	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IDM39_07560	COG2996	Protein conserved in bacteria
IDM39_07570	COG0475	glutathione-regulated potassium exporter activity
IDM39_07580	COG1490	D-aminoacyl-tRNA deacylase activity
IDM39_07585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IDM39_07590	COG0587	DNA-directed DNA polymerase activity
IDM39_07600	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IDM39_07605	COG0488	(ABC) transporter
IDM39_07610	COG0617	tRNA 3'-terminal CCA addition
IDM39_07620	COG1266	CAAX protease self-immunity
IDM39_07625	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IDM39_07630	COG0004	ammonium transporteR
IDM39_07640	COG0366	Alpha amylase catalytic
IDM39_07640	COG5263	repeat protein
IDM39_07645	COG1316	TRANSCRIPTIONal
IDM39_07650	COG1216	Glycosyl transferase, family 2
IDM39_07665	COG1216	Glycosyl transferase, family 2
IDM39_07675	COG0438	transferase activity, transferring glycosyl groups
IDM39_07680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IDM39_07685	COG0489	protein tyrosine kinase activity
IDM39_07700	COG0233	cytoplasmic translational termination
IDM39_07710	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IDM39_07715	COG0052	Belongs to the universal ribosomal protein uS2 family
IDM39_07720	COG2827	Endonuclease containing a URI domain
IDM39_07725	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IDM39_07730	COG0204	Acyl-transferase
IDM39_07735	COG3883	PFAM NLP P60 protein
IDM39_07735	COG0791	NLP P60 protein
IDM39_07750	COG3763	UPF0154 protein
IDM39_07755	COG4224	UPF0291 protein
IDM39_07760	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IDM39_07780	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IDM39_07780	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
IDM39_07785	COG1234	tRNA 3'-trailer cleavage
IDM39_07800	COG0484	heat shock protein binding
IDM39_07805	COG0443	Heat shock 70 kDa protein
IDM39_07815	COG1420	regulation of RNA biosynthetic process
IDM39_07845	COG1216	Glycosyl transferase, family 2
IDM39_07855	COG0463	Glycosyl transferase, family 2
IDM39_07865	COG1705	Flagellar rod assembly protein muramidase FlgJ
IDM39_07880	COG0562	UDP-galactopyranose mutase
IDM39_07905	COG0024	Methionine aminopeptidase
IDM39_07925	COG1705	Flagellar rod assembly protein muramidase FlgJ
IDM39_07925	COG1388	LysM domain
IDM39_07950	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IDM39_07955	COG1682	transport, permease protein
IDM39_07960	COG1134	teichoic acid transport
IDM39_07960	COG1388	LysM domain
IDM39_07990	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IDM39_07995	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IDM39_08000	COG1216	Glycosyl transferase, family 2
IDM39_08005	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IDM39_08030	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IDM39_08085	COG3883	PFAM NLP P60 protein
IDM39_08085	COG0791	NLP P60 protein
IDM39_08150	COG0463	Glycosyl transferase, family 2
IDM39_08165	COG3706	GGDEF domain
IDM39_08200	COG2309	aminopeptidase activity
IDM39_08215	COG0564	pseudouridine synthase activity
IDM39_08220	COG1278	Cold shock
IDM39_08230	COG2814	Major facilitator Superfamily
IDM39_08240	COG0741	lytic transglycosylase activity
IDM39_08245	COG1072	(Pantothenic acid kinase))
IDM39_08250	COG3973	AAA domain
IDM39_08260	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IDM39_08265	COG1058	Belongs to the CinA family
IDM39_08265	COG1546	Belongs to the CinA family
IDM39_08270	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IDM39_08275	COG1426	Protein conserved in bacteria
IDM39_08280	COG0612	Peptidase, M16
IDM39_08285	COG0612	Peptidase, M16
IDM39_08300	COG0028	Belongs to the TPP enzyme family
IDM39_08320	COG4717	serine-type aminopeptidase activity
IDM39_08340	COG3679	Belongs to the UPF0342 family
IDM39_08345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IDM39_08350	COG1438	arginine binding
IDM39_08370	COG0018	arginyl-trna synthetase
IDM39_08385	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IDM39_08395	COG1121	(ABC) transporter
IDM39_08410	COG2826	transposase and inactivated derivatives, IS30 family
IDM39_08420	COG1597	lipid kinase activity
IDM39_08425	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IDM39_08430	COG0154	amidase activity
IDM39_08435	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IDM39_08440	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
IDM39_08440	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IDM39_08450	COG2936	dipeptidyl-peptidase activity
IDM39_08465	COG1695	Transcriptional regulator
IDM39_08475	COG1914	H( )-stimulated, divalent metal cation uptake system
IDM39_08495	COG0667	Aldo Keto reductase
IDM39_08500	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IDM39_08505	COG4721	ABC-type cobalt transport system, permease component
IDM39_08510	COG1122	ATPase activity
IDM39_08525	COG0710	3-dehydroquinate dehydratase activity
IDM39_08530	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IDM39_08535	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IDM39_08540	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IDM39_08545	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IDM39_08550	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
IDM39_08555	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IDM39_08570	COG4684	Psort location CytoplasmicMembrane, score
IDM39_08575	COG0436	Aminotransferase
IDM39_08590	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IDM39_08595	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IDM39_08600	COG0436	Aminotransferase
IDM39_08605	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IDM39_08610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IDM39_08620	COG2171	N-acyltransferase activity
IDM39_08630	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IDM39_08635	COG0527	aspartate kinase activity
IDM39_08645	COG1609	Transcriptional regulator
IDM39_08650	COG0083	homoserine kinase activity
IDM39_08665	COG1321	iron dependent repressor
IDM39_08670	COG3764	Sortase (surface protein transpeptidase)
IDM39_08690	COG0513	Belongs to the DEAD box helicase family
IDM39_08695	COG0673	inositol 2-dehydrogenase activity
IDM39_08700	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IDM39_08710	COG0501	Belongs to the peptidase M48B family
IDM39_08715	COG1704	LemA family
IDM39_08725	COG4115	mRNA cleavage
IDM39_08730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IDM39_08745	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IDM39_08755	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IDM39_08760	COG0439	Biotin carboxylase
IDM39_08775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IDM39_08780	COG1028	Short-chain dehydrogenase reductase Sdr
IDM39_08785	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IDM39_08790	COG2070	2-Nitropropane dioxygenase
IDM39_08795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IDM39_08800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IDM39_08805	COG1846	Transcriptional regulator
IDM39_08810	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IDM39_08820	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IDM39_08825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IDM39_08835	COG0505	Belongs to the CarA family
IDM39_08845	COG0564	pseudouridine synthase activity
IDM39_08855	COG0328	RNA-DNA hybrid ribonuclease activity
IDM39_08860	COG1757	Na H antiporter
IDM39_08865	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IDM39_08870	COG1113	amino acid transport
IDM39_09090	COG0629	single-stranded DNA binding
IDM39_09150	COG1396	sequence-specific DNA binding
IDM39_09170	COG4974	Belongs to the 'phage' integrase family
IDM39_09185	COG0656	L-ascorbic acid biosynthetic process
IDM39_09200	COG0105	UTP biosynthetic process
IDM39_09210	COG0583	DNA-binding transcription factor activity
IDM39_09215	COG0126	phosphoglycerate kinase activity
IDM39_09265	COG0588	phosphoglycerate mutase activity
IDM39_09275	COG3716	PTS system mannose fructose sorbose family IID component
IDM39_09280	COG3715	PTS system
IDM39_09295	COG1397	ADP-ribosylglycohydrolase
IDM39_09355	COG1368	sulfuric ester hydrolase activity
IDM39_09370	COG0438	transferase activity, transferring glycosyl groups
IDM39_09375	COG0438	transferase activity, transferring glycosyl groups
IDM39_09380	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IDM39_09385	COG0284	orotidine-5'-phosphate decarboxylase activity
IDM39_09390	COG0167	dihydroorotate dehydrogenase activity
IDM39_09395	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IDM39_09400	COG0505	Belongs to the CarA family
IDM39_09405	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IDM39_09410	COG0540	Belongs to the ATCase OTCase family
IDM39_09430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IDM39_09435	COG4856	YbbR-like protein
IDM39_09450	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IDM39_09455	COG2176	DNA-directed DNA polymerase activity
IDM39_09465	COG0802	atpase or kinase
IDM39_09470	COG0280	phosphate acetyltransferase
IDM39_09475	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IDM39_09485	COG2076	Multidrug Resistance protein
IDM39_09490	COG2076	Multidrug Resistance protein
IDM39_09495	COG1126	abc transporter atp-binding protein
IDM39_09500	COG0765	amino acid transport
IDM39_09505	COG2814	Major facilitator Superfamily
IDM39_09525	COG0557	exoribonuclease II activity
IDM39_09535	COG2814	Major facilitator Superfamily
IDM39_09540	COG0154	amidase activity
IDM39_09560	COG0149	triose-phosphate isomerase activity
IDM39_09565	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IDM39_09570	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IDM39_09580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IDM39_09585	COG0492	ferredoxin-NADP+ reductase activity
IDM39_09610	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IDM39_09615	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IDM39_09620	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IDM39_09625	COG1950	PFAM Membrane protein of
IDM39_09635	COG0589	response to stress
IDM39_09645	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IDM39_09655	COG1177	transmembrane transport
IDM39_09665	COG3842	ATPase activity
IDM39_09680	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IDM39_09685	COG0049	tRNA binding
IDM39_09690	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IDM39_09700	COG4608	Belongs to the ABC transporter superfamily
IDM39_09705	COG0444	Belongs to the ABC transporter superfamily
IDM39_09710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IDM39_09715	COG0601	transmembrane transport
IDM39_09725	COG0460	homoserine dehydrogenase
IDM39_09730	COG0626	cystathionine gamma-synthase activity
IDM39_09735	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IDM39_09745	COG1744	ABC transporter substrate-binding protein PnrA-like
IDM39_09750	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IDM39_09755	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IDM39_09770	COG1302	Protein conserved in bacteria
IDM39_09775	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IDM39_09785	COG2017	converts alpha-aldose to the beta-anomer
IDM39_09800	COG4975	Glucose uptake
IDM39_09805	COG3850	Histidine kinase
IDM39_09805	COG5002	protein histidine kinase activity
IDM39_09810	COG0745	RESPONSE REGULATOR receiver
IDM39_09815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IDM39_09820	COG0402	S-adenosylhomocysteine deaminase activity
IDM39_09825	COG0673	inositol 2-dehydrogenase activity
IDM39_09830	COG0741	lytic transglycosylase activity
IDM39_09850	COG0668	transmembrane transport
IDM39_09860	COG1126	abc transporter atp-binding protein
IDM39_09865	COG0765	amino acid transport
IDM39_09900	COG0516	GMP reductase activity
IDM39_09980	COG0494	nUDIX hydrolase
IDM39_10030	COG1869	D-ribose catabolic process
IDM39_10035	COG1609	Transcriptional regulator
IDM39_10055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IDM39_10070	COG1609	Transcriptional regulator
IDM39_10085	COG2223	nitrite transmembrane transporter activity
IDM39_10095	COG0318	PFAM AMP-dependent synthetase and ligase
IDM39_10105	COG1116	anion transmembrane transporter activity
IDM39_10110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IDM39_10115	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IDM39_10120	COG0285	dihydrofolate synthase activity
IDM39_10125	COG0302	gtp cyclohydrolase
IDM39_10130	COG0302	gtp cyclohydrolase
IDM39_10130	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IDM39_10150	COG0561	phosphatase activity
IDM39_10160	COG0823	Involved in the tonB-independent uptake of proteins
IDM39_10160	COG1506	peptidase
IDM39_10160	COG4946	Tricorn protease homolog
IDM39_10165	COG1464	Belongs to the NlpA lipoprotein family
IDM39_10180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IDM39_10195	COG1609	Transcriptional regulator
IDM39_10225	COG0577	efflux transmembrane transporter activity
IDM39_10230	COG1136	(ABC) transporter
IDM39_10235	COG3759	membrane
IDM39_10270	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IDM39_10275	COG2235	arginine
IDM39_10285	COG2217	Heavy metal translocating P-type atpase
IDM39_10330	COG2217	Heavy metal translocating P-type atpase
IDM39_10350	COG1309	transcriptional regulator
IDM39_10375	COG3711	transcriptional antiterminator
IDM39_10380	COG2723	6-phospho-beta-galactosidase activity
IDM39_10385	COG1940	carbohydrate kinase activity
IDM39_10410	COG2183	response to ionizing radiation
IDM39_10420	COG2873	o-acetylhomoserine
IDM39_10425	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IDM39_10430	COG1040	competence protein
IDM39_10435	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IDM39_10515	COG2176	DNA-directed DNA polymerase activity
IDM39_10520	COG0442	prolyl-tRNA aminoacylation
IDM39_10525	COG0750	zinc metalloprotease
IDM39_10530	COG4589	Belongs to the CDS family
IDM39_10535	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IDM39_10540	COG0561	phosphatase activity
IDM39_10545	COG2246	polysaccharide biosynthetic process
IDM39_10570	COG1811	Na channel or pump
IDM39_10585	COG1174	glycine betaine transport
IDM39_10605	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IDM39_10610	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IDM39_10610	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IDM39_10615	COG0307	riboflavin synthase, alpha
IDM39_10620	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IDM39_10620	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IDM39_10625	COG2076	Multidrug Resistance protein
IDM39_10630	COG2076	Multidrug Resistance protein
IDM39_10640	COG1435	thymidine kinase activity
IDM39_10655	COG1307	EDD domain protein, DegV family
IDM39_10660	COG0656	L-ascorbic acid biosynthetic process
IDM39_10665	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IDM39_10690	COG4166	transmembrane transport
IDM39_10710	COG2826	transposase and inactivated derivatives, IS30 family
IDM39_10750	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IDM39_10755	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IDM39_10765	COG2252	PERMEase
IDM39_10775	COG0352	thiamine-phosphate diphosphorylase activity
IDM39_10780	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IDM39_10790	COG2814	Major facilitator Superfamily
IDM39_10795	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IDM39_10805	COG2188	Transcriptional regulator
IDM39_10815	COG0577	efflux transmembrane transporter activity
IDM39_10815	COG1136	(ABC) transporter
IDM39_10825	COG0561	phosphatase activity
IDM39_10830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IDM39_10830	COG2169	Transcriptional regulator
IDM39_10840	COG0561	phosphatase activity
IDM39_10860	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IDM39_10865	COG0772	Belongs to the SEDS family
IDM39_10875	COG1077	Cell shape determining protein MreB Mrl
IDM39_10880	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IDM39_10885	COG1079	Belongs to the binding-protein-dependent transport system permease family
IDM39_10890	COG4603	Belongs to the binding-protein-dependent transport system permease family
IDM39_10895	COG3845	ABC transporter
IDM39_10900	COG1744	ABC transporter substrate-binding protein PnrA-like
IDM39_10915	COG0640	Transcriptional regulator
IDM39_10920	COG0628	permease
IDM39_10925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IDM39_10945	COG0386	Belongs to the glutathione peroxidase family
IDM39_10955	COG0588	phosphoglycerate mutase activity
IDM39_10965	COG0492	ferredoxin-NADP+ reductase activity
IDM39_10980	COG1744	ABC transporter substrate-binding protein PnrA-like
IDM39_10985	COG1744	ABC transporter substrate-binding protein PnrA-like
IDM39_10995	COG2832	Protein of unknown function (DUF454)
IDM39_11030	COG2814	Major facilitator Superfamily
IDM39_11035	COG0305	Participates in initiation and elongation during chromosome replication
IDM39_11040	COG0359	binds to the 23S rRNA
IDM39_11050	COG4608	Belongs to the ABC transporter superfamily
IDM39_11055	COG0444	Belongs to the ABC transporter superfamily
IDM39_11060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IDM39_11065	COG0601	transmembrane transport
IDM39_11070	COG4166	transmembrane transport
IDM39_11075	COG0765	amino acid transport
IDM39_11080	COG0765	amino acid transport
IDM39_11085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IDM39_11090	COG1126	abc transporter atp-binding protein
IDM39_11105	COG0194	GDP metabolic process
IDM39_11110	COG1268	BioY protein
IDM39_11145	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IDM39_11160	COG3973	AAA domain
IDM39_11180	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IDM39_11190	COG1696	Membrane protein involved in D-alanine export
IDM39_11210	COG2337	Toxic component of a toxin-antitoxin (TA) module
IDM39_11225	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IDM39_11230	COG0504	CTP synthase activity
IDM39_11245	COG3343	RNA polymerase activity
IDM39_11250	COG0561	phosphatase activity
IDM39_11255	COG1078	dGTPase activity
IDM39_11265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IDM39_11270	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IDM39_11290	COG0745	RESPONSE REGULATOR receiver
IDM39_11325	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IDM39_11330	COG0629	single-stranded DNA binding
IDM39_11335	COG0360	Binds together with S18 to 16S ribosomal RNA
IDM39_11350	COG1957	nucleoside hydrolase
IDM39_11355	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IDM39_11365	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IDM39_11370	COG1051	belongs to the nudix hydrolase family
IDM39_11385	COG2814	Major facilitator Superfamily
IDM39_11390	COG1064	alcohol dehydrogenase
IDM39_11395	COG1074	ATP-dependent DNA helicase activity
IDM39_11400	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IDM39_11420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IDM39_11425	COG2197	response regulator
IDM39_11430	COG4585	Histidine kinase
IDM39_11440	COG2409	Drug exporters of the RND superfamily
IDM39_11445	COG0531	amino acid
IDM39_11450	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IDM39_11460	COG1902	pentaerythritol trinitrate reductase activity
IDM39_11465	COG0626	cystathionine gamma-synthase activity
IDM39_11490	COG2244	polysaccharide biosynthetic process
IDM39_11500	COG0438	transferase activity, transferring glycosyl groups
IDM39_11505	COG0495	leucyl-tRNA aminoacylation
IDM39_11510	COG0671	phosphoesterase, PA-phosphatase related
IDM39_11520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IDM39_11545	COG2723	6-phospho-beta-galactosidase activity
IDM39_11575	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IDM39_11590	COG0024	Methionine aminopeptidase
IDM39_11600	COG1316	TRANSCRIPTIONal
IDM39_11610	COG2205	protein histidine kinase activity
IDM39_11615	COG0745	RESPONSE REGULATOR receiver
IDM39_11620	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IDM39_11635	COG2207	Transcriptional regulator
IDM39_11655	COG0308	aminopeptidase N
IDM39_11660	COG0833	amino acid
IDM39_11665	COG2040	homocysteine
IDM39_11670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IDM39_11675	COG0542	response to heat
IDM39_11690	COG0395	ABC-type sugar transport system, permease component
IDM39_11695	COG1175	transmembrane transport
IDM39_11700	COG3842	ATPase activity
IDM39_11755	COG0107	imidazoleglycerol-phosphate synthase activity
IDM39_11760	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IDM39_11770	COG0131	Imidazoleglycerol-phosphate dehydratase
IDM39_11775	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IDM39_11785	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IDM39_11895	COG0438	transferase activity, transferring glycosyl groups
IDM39_11920	COG2084	Dehydrogenase
IDM39_11925	COG1028	Short-chain dehydrogenase reductase Sdr
IDM39_11935	COG1620	l-lactate permease
IDM39_11940	COG4989	oxidoreductase activity
IDM39_11945	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IDM39_11950	COG2233	PERMEase
IDM39_11965	COG1956	GAF domain-containing protein
IDM39_11980	COG1132	(ABC) transporter
IDM39_11985	COG1132	(ABC) transporter
IDM39_11990	COG0747	negative chemotaxis
IDM39_11995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IDM39_12000	COG0601	transmembrane transport
IDM39_12005	COG4608	Belongs to the ABC transporter superfamily
IDM39_12010	COG0444	Belongs to the ABC transporter superfamily
IDM39_12015	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
IDM39_12020	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IDM39_12025	COG2211	Major facilitator Superfamily
IDM39_12025	COG2190	(PTS) system
IDM39_12045	COG0436	Aminotransferase
IDM39_12055	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IDM39_12060	COG2801	Transposase and inactivated derivatives
IDM39_12070	COG2723	6-phospho-beta-galactosidase activity
IDM39_12075	COG2723	6-phospho-beta-galactosidase activity
IDM39_12080	COG1447	Phosphotransferase system cellobiose-specific component IIA
IDM39_12085	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IDM39_12090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IDM39_12100	COG1216	Glycosyl transferase, family 2
IDM39_12115	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IDM39_12175	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IDM39_12180	COG1737	Transcriptional regulator
IDM39_12190	COG0656	L-ascorbic acid biosynthetic process
IDM39_12195	COG2261	transglycosylase associated protein
IDM39_12260	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IDM39_12265	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IDM39_12280	COG0037	tRNA processing
IDM39_12290	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IDM39_12295	COG2244	polysaccharide biosynthetic process
IDM39_12300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IDM39_12305	COG0193	aminoacyl-tRNA hydrolase activity
IDM39_12315	COG0058	SHG alpha-glucan phosphorylase activity
IDM39_12320	COG0297	glycogen (starch) synthase activity
IDM39_12325	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IDM39_12345	COG1511	domain protein
IDM39_12345	COG1511	domain protein
IDM39_12350	COG1309	transcriptional regulator
IDM39_12365	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IDM39_12370	COG0477	Major facilitator Superfamily
IDM39_12385	COG0667	Aldo Keto reductase
IDM39_12395	COG2115	Belongs to the xylose isomerase family
IDM39_12405	COG2211	Major facilitator Superfamily
IDM39_12435	COG2818	Glycosylase
IDM39_12440	COG1968	undecaprenyl-diphosphatase activity
IDM39_12455	COG1695	Transcriptional regulator
IDM39_12460	COG1983	PspC domain protein
IDM39_12465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IDM39_12470	COG0737	Belongs to the 5'-nucleotidase family
IDM39_12485	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IDM39_12495	COG2723	6-phospho-beta-galactosidase activity
IDM39_12500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IDM39_12500	COG1263	PTS System
IDM39_12505	COG1316	TRANSCRIPTIONal
IDM39_12510	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IDM39_12515	COG2131	deaminase
IDM39_12520	COG4466	Protein conserved in bacteria
IDM39_12525	COG1253	flavin adenine dinucleotide binding
IDM39_12530	COG1253	flavin adenine dinucleotide binding
IDM39_12535	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IDM39_12540	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IDM39_12545	COG0084	hydrolase, TatD family'