locus-tag	class	description
EQZ96_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EQZ96_00010	COG0592	DNA-directed DNA polymerase activity
EQZ96_00015	COG2501	S4 domain
EQZ96_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EQZ96_00025	COG0187	DNA topoisomerase II activity
EQZ96_00040	COG2153	protein acetylation
EQZ96_00045	COG1368	sulfuric ester hydrolase activity
EQZ96_00065	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EQZ96_00125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQZ96_00125	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQZ96_00135	COG0084	hydrolase, TatD family'
EQZ96_00140	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EQZ96_00145	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EQZ96_00150	COG1253	flavin adenine dinucleotide binding
EQZ96_00155	COG1253	flavin adenine dinucleotide binding
EQZ96_00160	COG4466	Protein conserved in bacteria
EQZ96_00165	COG2131	deaminase
EQZ96_00170	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EQZ96_00175	COG1316	TRANSCRIPTIONal
EQZ96_00180	COG1263	PTS System
EQZ96_00180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQZ96_00195	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EQZ96_00210	COG0737	Belongs to the 5'-nucleotidase family
EQZ96_00215	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EQZ96_00220	COG1983	PspC domain protein
EQZ96_00225	COG1695	Transcriptional regulator
EQZ96_00240	COG1968	undecaprenyl-diphosphatase activity
EQZ96_00245	COG2818	Glycosylase
EQZ96_00270	COG3507	Belongs to the glycosyl hydrolase 43 family
EQZ96_00275	COG2211	Major facilitator Superfamily
EQZ96_00285	COG2115	Belongs to the xylose isomerase family
EQZ96_00295	COG0667	Aldo Keto reductase
EQZ96_00310	COG0477	Major facilitator Superfamily
EQZ96_00315	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQZ96_00330	COG1309	transcriptional regulator
EQZ96_00335	COG1511	domain protein
EQZ96_00335	COG1511	domain protein
EQZ96_00350	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EQZ96_00360	COG0058	SHG alpha-glucan phosphorylase activity
EQZ96_00370	COG0193	aminoacyl-tRNA hydrolase activity
EQZ96_00375	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EQZ96_00380	COG2244	polysaccharide biosynthetic process
EQZ96_00385	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EQZ96_00395	COG0037	tRNA processing
EQZ96_00410	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EQZ96_00415	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EQZ96_00480	COG2261	transglycosylase associated protein
EQZ96_00485	COG0656	L-ascorbic acid biosynthetic process
EQZ96_00500	COG2801	Transposase and inactivated derivatives
EQZ96_00505	COG1737	Transcriptional regulator
EQZ96_00510	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EQZ96_00550	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EQZ96_00565	COG1216	Glycosyl transferase, family 2
EQZ96_00570	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EQZ96_00575	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQZ96_00580	COG1447	Phosphotransferase system cellobiose-specific component IIA
EQZ96_00585	COG2723	6-phospho-beta-galactosidase activity
EQZ96_00590	COG2723	6-phospho-beta-galactosidase activity
EQZ96_00595	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQZ96_00605	COG0436	Aminotransferase
EQZ96_00625	COG2211	Major facilitator Superfamily
EQZ96_00625	COG2190	(PTS) system
EQZ96_00630	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EQZ96_00635	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EQZ96_00640	COG0444	Belongs to the ABC transporter superfamily
EQZ96_00645	COG4608	Belongs to the ABC transporter superfamily
EQZ96_00650	COG0601	transmembrane transport
EQZ96_00655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQZ96_00660	COG0747	negative chemotaxis
EQZ96_00665	COG1132	(ABC) transporter
EQZ96_00670	COG1132	(ABC) transporter
EQZ96_00685	COG1956	GAF domain-containing protein
EQZ96_00700	COG2233	PERMEase
EQZ96_00705	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EQZ96_00710	COG4989	oxidoreductase activity
EQZ96_00715	COG1620	l-lactate permease
EQZ96_00725	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ96_00730	COG2084	Dehydrogenase
EQZ96_00755	COG0438	transferase activity, transferring glycosyl groups
EQZ96_00850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQZ96_00865	COG3842	ATPase activity
EQZ96_00870	COG1175	transmembrane transport
EQZ96_00875	COG0395	ABC-type sugar transport system, permease component
EQZ96_00890	COG0542	response to heat
EQZ96_00895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQZ96_00900	COG2040	homocysteine
EQZ96_00905	COG0833	amino acid
EQZ96_00910	COG0308	aminopeptidase N
EQZ96_00930	COG2207	Transcriptional regulator
EQZ96_00945	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EQZ96_00950	COG0745	RESPONSE REGULATOR receiver
EQZ96_00955	COG2205	protein histidine kinase activity
EQZ96_00965	COG1316	TRANSCRIPTIONal
EQZ96_00975	COG0024	Methionine aminopeptidase
EQZ96_00985	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EQZ96_01000	COG2723	6-phospho-beta-galactosidase activity
EQZ96_01020	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EQZ96_01030	COG0671	phosphoesterase, PA-phosphatase related
EQZ96_01035	COG0495	leucyl-tRNA aminoacylation
EQZ96_01040	COG0438	transferase activity, transferring glycosyl groups
EQZ96_01050	COG2244	polysaccharide biosynthetic process
EQZ96_01065	COG0626	cystathionine gamma-synthase activity
EQZ96_01070	COG1902	pentaerythritol trinitrate reductase activity
EQZ96_01080	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EQZ96_01085	COG0531	amino acid
EQZ96_01090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EQZ96_01105	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EQZ96_01110	COG1074	ATP-dependent DNA helicase activity
EQZ96_01115	COG1064	alcohol dehydrogenase
EQZ96_01120	COG2814	Major facilitator Superfamily
EQZ96_01135	COG1051	belongs to the nudix hydrolase family
EQZ96_01140	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EQZ96_01150	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EQZ96_01165	COG0360	Binds together with S18 to 16S ribosomal RNA
EQZ96_01170	COG0629	single-stranded DNA binding
EQZ96_01175	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EQZ96_01205	COG0745	RESPONSE REGULATOR receiver
EQZ96_01225	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EQZ96_01230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EQZ96_01240	COG1078	dGTPase activity
EQZ96_01245	COG0561	phosphatase activity
EQZ96_01250	COG3343	RNA polymerase activity
EQZ96_01260	COG0504	CTP synthase activity
EQZ96_01265	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EQZ96_01280	COG2337	Toxic component of a toxin-antitoxin (TA) module
EQZ96_01300	COG1696	Membrane protein involved in D-alanine export
EQZ96_01310	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EQZ96_01330	COG3973	AAA domain
EQZ96_01345	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EQZ96_01350	COG2211	Major facilitator Superfamily
EQZ96_01375	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EQZ96_01375	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EQZ96_01380	COG1268	BioY protein
EQZ96_01385	COG0194	GDP metabolic process
EQZ96_01400	COG1126	abc transporter atp-binding protein
EQZ96_01405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQZ96_01410	COG0765	amino acid transport
EQZ96_01415	COG0765	amino acid transport
EQZ96_01420	COG4166	transmembrane transport
EQZ96_01425	COG0601	transmembrane transport
EQZ96_01430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQZ96_01435	COG0444	Belongs to the ABC transporter superfamily
EQZ96_01440	COG4608	Belongs to the ABC transporter superfamily
EQZ96_01450	COG0359	binds to the 23S rRNA
EQZ96_01455	COG0305	Participates in initiation and elongation during chromosome replication
EQZ96_01460	COG2814	Major facilitator Superfamily
EQZ96_01470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EQZ96_01495	COG2832	Protein of unknown function (DUF454)
EQZ96_01510	COG1744	ABC transporter substrate-binding protein PnrA-like
EQZ96_01525	COG0492	ferredoxin-NADP+ reductase activity
EQZ96_01540	COG0588	phosphoglycerate mutase activity
EQZ96_01545	COG0386	Belongs to the glutathione peroxidase family
EQZ96_01565	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQZ96_01570	COG0628	permease
EQZ96_01575	COG0640	Transcriptional regulator
EQZ96_01610	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EQZ96_01615	COG1077	Cell shape determining protein MreB Mrl
EQZ96_01625	COG0772	Belongs to the SEDS family
EQZ96_01630	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EQZ96_01650	COG0561	phosphatase activity
EQZ96_01655	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EQZ96_01655	COG2169	Transcriptional regulator
EQZ96_01660	COG0561	phosphatase activity
EQZ96_01670	COG0577	efflux transmembrane transporter activity
EQZ96_01670	COG1136	(ABC) transporter
EQZ96_01690	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EQZ96_01695	COG2814	Major facilitator Superfamily
EQZ96_01705	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EQZ96_01710	COG0352	thiamine-phosphate diphosphorylase activity
EQZ96_01720	COG2252	PERMEase
EQZ96_01730	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EQZ96_01745	COG2801	Transposase and inactivated derivatives
EQZ96_01765	COG1063	alcohol dehydrogenase
EQZ96_01770	COG4166	transmembrane transport
EQZ96_01775	COG1228	amidohydrolase
EQZ96_01795	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EQZ96_01800	COG0656	L-ascorbic acid biosynthetic process
EQZ96_01805	COG1307	EDD domain protein, DegV family
EQZ96_01820	COG1435	thymidine kinase activity
EQZ96_01825	COG2076	Multidrug Resistance protein
EQZ96_01830	COG2076	Multidrug Resistance protein
EQZ96_01835	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EQZ96_01835	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EQZ96_01840	COG0307	riboflavin synthase, alpha
EQZ96_01845	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EQZ96_01845	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EQZ96_01850	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EQZ96_01860	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EQZ96_01865	COG1125	glycine betaine transport
EQZ96_01865	COG0517	IMP dehydrogenase activity
EQZ96_01870	COG1174	glycine betaine transport
EQZ96_01880	COG1979	alcohol dehydrogenase
EQZ96_01885	COG1811	Na channel or pump
EQZ96_01915	COG2246	polysaccharide biosynthetic process
EQZ96_01920	COG0561	phosphatase activity
EQZ96_01925	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EQZ96_01930	COG4589	Belongs to the CDS family
EQZ96_01935	COG0750	zinc metalloprotease
EQZ96_01940	COG0442	prolyl-tRNA aminoacylation
EQZ96_01945	COG2176	DNA-directed DNA polymerase activity
EQZ96_01990	COG2801	Transposase and inactivated derivatives
EQZ96_02025	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EQZ96_02030	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EQZ96_02035	COG1040	competence protein
EQZ96_02040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EQZ96_02055	COG2183	response to ionizing radiation
EQZ96_02075	COG2801	Transposase and inactivated derivatives
EQZ96_02085	COG1940	carbohydrate kinase activity
EQZ96_02090	COG2723	6-phospho-beta-galactosidase activity
EQZ96_02095	COG3711	transcriptional antiterminator
EQZ96_02115	COG1309	transcriptional regulator
EQZ96_02135	COG2217	Heavy metal translocating P-type atpase
EQZ96_02140	COG2814	Major facilitator Superfamily
EQZ96_02190	COG0438	transferase activity, transferring glycosyl groups
EQZ96_02240	COG2217	Heavy metal translocating P-type atpase
EQZ96_02250	COG2235	arginine
EQZ96_02255	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EQZ96_02260	COG0531	amino acid
EQZ96_02280	COG3759	membrane
EQZ96_02285	COG1136	(ABC) transporter
EQZ96_02290	COG0577	efflux transmembrane transporter activity
EQZ96_02320	COG1609	Transcriptional regulator
EQZ96_02335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EQZ96_02355	COG1312	Catalyzes the dehydration of D-mannonate
EQZ96_02360	COG1904	glucuronate isomerase
EQZ96_02365	COG0800	Aldolase
EQZ96_02370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQZ96_02375	COG1464	Belongs to the NlpA lipoprotein family
EQZ96_02380	COG4946	Tricorn protease homolog
EQZ96_02380	COG0823	Involved in the tonB-independent uptake of proteins
EQZ96_02380	COG1506	peptidase
EQZ96_02395	COG0561	phosphatase activity
EQZ96_02420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EQZ96_02420	COG0302	gtp cyclohydrolase
EQZ96_02425	COG0302	gtp cyclohydrolase
EQZ96_02430	COG0285	dihydrofolate synthase activity
EQZ96_02440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EQZ96_02455	COG0318	PFAM AMP-dependent synthetase and ligase
EQZ96_02495	COG1609	Transcriptional regulator
EQZ96_02510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQZ96_02530	COG1609	Transcriptional regulator
EQZ96_02535	COG1869	D-ribose catabolic process
EQZ96_02540	COG0738	Major facilitator superfamily
EQZ96_02570	COG0494	nUDIX hydrolase
EQZ96_02650	COG0516	GMP reductase activity
EQZ96_02685	COG1126	abc transporter atp-binding protein
EQZ96_02695	COG0668	transmembrane transport
EQZ96_02715	COG0741	lytic transglycosylase activity
EQZ96_02725	COG0402	S-adenosylhomocysteine deaminase activity
EQZ96_02730	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EQZ96_02735	COG0745	RESPONSE REGULATOR receiver
EQZ96_02740	COG3850	Histidine kinase
EQZ96_02740	COG5002	protein histidine kinase activity
EQZ96_02745	COG4975	Glucose uptake
EQZ96_02755	COG2017	converts alpha-aldose to the beta-anomer
EQZ96_02765	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EQZ96_02770	COG1302	Protein conserved in bacteria
EQZ96_02785	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EQZ96_02790	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EQZ96_02805	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EQZ96_02810	COG0626	cystathionine gamma-synthase activity
EQZ96_02815	COG0460	homoserine dehydrogenase
EQZ96_02825	COG0601	transmembrane transport
EQZ96_02830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQZ96_02835	COG0444	Belongs to the ABC transporter superfamily
EQZ96_02840	COG4608	Belongs to the ABC transporter superfamily
EQZ96_02850	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EQZ96_02855	COG0049	tRNA binding
EQZ96_02860	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EQZ96_02870	COG3842	ATPase activity
EQZ96_02875	COG1176	ABC-type spermidine putrescine transport system, permease component I
EQZ96_02880	COG1177	transmembrane transport
EQZ96_02890	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EQZ96_02900	COG0589	response to stress
EQZ96_02910	COG1950	PFAM Membrane protein of
EQZ96_02915	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EQZ96_02920	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EQZ96_02955	COG0492	ferredoxin-NADP+ reductase activity
EQZ96_02960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EQZ96_02970	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQZ96_02975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EQZ96_02980	COG0149	triose-phosphate isomerase activity
EQZ96_03000	COG0154	amidase activity
EQZ96_03015	COG0557	exoribonuclease II activity
EQZ96_03030	COG2814	Major facilitator Superfamily
EQZ96_03035	COG0765	amino acid transport
EQZ96_03040	COG1126	abc transporter atp-binding protein
EQZ96_03045	COG2076	Multidrug Resistance protein
EQZ96_03050	COG2076	Multidrug Resistance protein
EQZ96_03065	COG0280	phosphate acetyltransferase
EQZ96_03070	COG0802	atpase or kinase
EQZ96_03085	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EQZ96_03100	COG4856	YbbR-like protein
EQZ96_03105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EQZ96_03125	COG0540	Belongs to the ATCase OTCase family
EQZ96_03130	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EQZ96_03135	COG0505	Belongs to the CarA family
EQZ96_03140	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EQZ96_03145	COG0167	dihydroorotate dehydrogenase activity
EQZ96_03150	COG0284	orotidine-5'-phosphate decarboxylase activity
EQZ96_03155	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EQZ96_03160	COG0438	transferase activity, transferring glycosyl groups
EQZ96_03165	COG0438	transferase activity, transferring glycosyl groups
EQZ96_03180	COG1368	sulfuric ester hydrolase activity
EQZ96_03240	COG1397	ADP-ribosylglycohydrolase
EQZ96_03255	COG3715	PTS system
EQZ96_03260	COG3716	PTS system mannose fructose sorbose family IID component
EQZ96_03270	COG0588	phosphoglycerate mutase activity
EQZ96_03320	COG0126	phosphoglycerate kinase activity
EQZ96_03325	COG0583	DNA-binding transcription factor activity
EQZ96_03335	COG0105	UTP biosynthetic process
EQZ96_03340	COG1012	belongs to the aldehyde dehydrogenase family
EQZ96_03340	COG1454	alcohol dehydrogenase
EQZ96_03385	COG1113	amino acid transport
EQZ96_03390	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EQZ96_03400	COG0328	RNA-DNA hybrid ribonuclease activity
EQZ96_03410	COG0564	pseudouridine synthase activity
EQZ96_03420	COG0505	Belongs to the CarA family
EQZ96_03430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EQZ96_03435	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EQZ96_03445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EQZ96_03450	COG1846	Transcriptional regulator
EQZ96_03455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EQZ96_03460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EQZ96_03465	COG2070	2-Nitropropane dioxygenase
EQZ96_03470	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EQZ96_03475	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ96_03480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EQZ96_03495	COG0439	Biotin carboxylase
EQZ96_03500	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EQZ96_03510	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EQZ96_03525	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EQZ96_03530	COG4115	mRNA cleavage
EQZ96_03540	COG1704	LemA family
EQZ96_03545	COG0501	Belongs to the peptidase M48B family
EQZ96_03555	COG2801	Transposase and inactivated derivatives
EQZ96_03570	COG2801	Transposase and inactivated derivatives
EQZ96_03575	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EQZ96_03580	COG0673	inositol 2-dehydrogenase activity
EQZ96_03585	COG0513	Belongs to the DEAD box helicase family
EQZ96_03605	COG3764	Sortase (surface protein transpeptidase)
EQZ96_03610	COG1321	iron dependent repressor
EQZ96_03620	COG2801	Transposase and inactivated derivatives
EQZ96_03635	COG0083	homoserine kinase activity
EQZ96_03640	COG1609	Transcriptional regulator
EQZ96_03650	COG0527	aspartate kinase activity
EQZ96_03655	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EQZ96_03665	COG2171	N-acyltransferase activity
EQZ96_03675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EQZ96_03680	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EQZ96_03685	COG0436	Aminotransferase
EQZ96_03690	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EQZ96_03695	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EQZ96_03700	COG0582	viral genome integration into host DNA
EQZ96_03725	COG1396	sequence-specific DNA binding
EQZ96_03845	COG1783	phage Terminase large subunit
EQZ96_03870	COG0228	four-way junction DNA binding
EQZ96_03960	COG0436	Aminotransferase
EQZ96_03965	COG4684	Psort location CytoplasmicMembrane, score
EQZ96_03980	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EQZ96_03985	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EQZ96_03990	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EQZ96_03995	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EQZ96_04000	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EQZ96_04005	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EQZ96_04010	COG0710	3-dehydroquinate dehydratase activity
EQZ96_04025	COG1122	ATPase activity
EQZ96_04030	COG4721	ABC-type cobalt transport system, permease component
EQZ96_04035	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EQZ96_04040	COG0667	Aldo Keto reductase
EQZ96_04060	COG1914	H( )-stimulated, divalent metal cation uptake system
EQZ96_04070	COG1695	Transcriptional regulator
EQZ96_04095	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EQZ96_04095	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EQZ96_04100	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EQZ96_04105	COG0154	amidase activity
EQZ96_04110	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EQZ96_04115	COG1597	lipid kinase activity
EQZ96_04135	COG1121	(ABC) transporter
EQZ96_04145	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EQZ96_04160	COG0018	arginyl-trna synthetase
EQZ96_04180	COG1438	arginine binding
EQZ96_04185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EQZ96_04190	COG3679	Belongs to the UPF0342 family
EQZ96_04205	COG4717	serine-type aminopeptidase activity
EQZ96_04225	COG0028	Belongs to the TPP enzyme family
EQZ96_04240	COG0612	Peptidase, M16
EQZ96_04245	COG0612	Peptidase, M16
EQZ96_04250	COG1426	Protein conserved in bacteria
EQZ96_04255	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EQZ96_04260	COG1546	Belongs to the CinA family
EQZ96_04260	COG1058	Belongs to the CinA family
EQZ96_04265	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EQZ96_04275	COG3973	AAA domain
EQZ96_04285	COG0741	lytic transglycosylase activity
EQZ96_04290	COG2814	Major facilitator Superfamily
EQZ96_04300	COG1278	Cold shock
EQZ96_04305	COG0564	pseudouridine synthase activity
EQZ96_04330	COG2309	aminopeptidase activity
EQZ96_04360	COG2199	diguanylate cyclase activity
EQZ96_04380	COG0463	Glycosyl transferase, family 2
EQZ96_04445	COG3883	PFAM NLP P60 protein
EQZ96_04445	COG0791	NLP P60 protein
EQZ96_04485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EQZ96_04505	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EQZ96_04515	COG3475	LICD family
EQZ96_04520	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EQZ96_04525	COG1063	alcohol dehydrogenase
EQZ96_04530	COG1134	teichoic acid transport
EQZ96_04530	COG1388	LysM domain
EQZ96_04535	COG1682	transport, permease protein
EQZ96_04545	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EQZ96_04575	COG1705	Flagellar rod assembly protein muramidase FlgJ
EQZ96_04575	COG1388	LysM domain
EQZ96_04595	COG0024	Methionine aminopeptidase
EQZ96_04620	COG0562	UDP-galactopyranose mutase
EQZ96_04635	COG1705	Flagellar rod assembly protein muramidase FlgJ
EQZ96_04645	COG0463	Glycosyl transferase, family 2
EQZ96_04655	COG1216	Glycosyl transferase, family 2
EQZ96_04685	COG1420	regulation of RNA biosynthetic process
EQZ96_04695	COG0443	Heat shock 70 kDa protein
EQZ96_04700	COG0484	heat shock protein binding
EQZ96_04715	COG1234	tRNA 3'-trailer cleavage
EQZ96_04720	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EQZ96_04720	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EQZ96_04740	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EQZ96_04745	COG4224	UPF0291 protein
EQZ96_04750	COG3763	UPF0154 protein
EQZ96_04765	COG3883	PFAM NLP P60 protein
EQZ96_04765	COG0791	NLP P60 protein
EQZ96_04770	COG0204	Acyl-transferase
EQZ96_04775	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EQZ96_04780	COG2827	Endonuclease containing a URI domain
EQZ96_04785	COG0052	Belongs to the universal ribosomal protein uS2 family
EQZ96_04790	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EQZ96_04800	COG0233	cytoplasmic translational termination
EQZ96_04815	COG0489	protein tyrosine kinase activity
EQZ96_04825	COG0438	transferase activity, transferring glycosyl groups
EQZ96_04835	COG1216	Glycosyl transferase, family 2
EQZ96_04850	COG1216	Glycosyl transferase, family 2
EQZ96_04855	COG1316	TRANSCRIPTIONal
EQZ96_04860	COG5263	repeat protein
EQZ96_04860	COG0366	Alpha amylase catalytic
EQZ96_04870	COG0004	ammonium transporteR
EQZ96_04875	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EQZ96_04885	COG1136	(ABC) transporter
EQZ96_04895	COG0617	tRNA 3'-terminal CCA addition
EQZ96_04900	COG0488	(ABC) transporter
EQZ96_04905	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EQZ96_04915	COG0587	DNA-directed DNA polymerase activity
EQZ96_04920	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EQZ96_04925	COG1490	D-aminoacyl-tRNA deacylase activity
EQZ96_04935	COG0475	glutathione-regulated potassium exporter activity
EQZ96_04945	COG2996	Protein conserved in bacteria
EQZ96_04960	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EQZ96_04965	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EQZ96_04970	COG1187	pseudouridine synthase activity
EQZ96_04985	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EQZ96_04995	COG0514	ATP-dependent DNA helicase (RecQ)
EQZ96_05005	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EQZ96_05010	COG0539	negative regulation of cytoplasmic translation
EQZ96_05015	COG1160	GTP binding
EQZ96_05025	COG0351	phosphomethylpyrimidine kinase
EQZ96_05030	COG4720	Psort location CytoplasmicMembrane, score
EQZ96_05035	COG2807	transmembrane transport
EQZ96_05045	COG0420	3'-5' exonuclease activity
EQZ96_05050	COG0419	ATPase involved in DNA repair
EQZ96_05085	COG0457	Tetratricopeptide repeat
EQZ96_05090	COG0071	Belongs to the small heat shock protein (HSP20) family
EQZ96_05095	COG2384	SAM-dependent methyltransferase
EQZ96_05100	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EQZ96_05110	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EQZ96_05130	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EQZ96_05135	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EQZ96_05155	COG0577	efflux transmembrane transporter activity
EQZ96_05160	COG1136	(ABC) transporter
EQZ96_05175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQZ96_05185	COG0281	malic enzyme
EQZ96_05190	COG0583	DNA-binding transcription factor activity
EQZ96_05195	COG4221	oxidoreductase activity
EQZ96_05200	COG0531	amino acid
EQZ96_05210	COG4708	membrane
EQZ96_05215	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ96_05245	COG0481	GTPase activity
EQZ96_05255	COG0531	amino acid
EQZ96_05275	COG2723	6-phospho-beta-galactosidase activity
EQZ96_05285	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EQZ96_05295	COG0306	phosphate transporter
EQZ96_05305	COG1609	Transcriptional regulator
EQZ96_05315	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQZ96_05315	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQZ96_05315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQZ96_05320	COG1105	Belongs to the carbohydrate kinase PfkB family
EQZ96_05325	COG1349	DNA-binding transcription factor activity
EQZ96_05330	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
EQZ96_05335	COG0446	pyridine nucleotide-disulphide oxidoreductase
EQZ96_05365	COG1397	ADP-ribosylglycohydrolase
EQZ96_05370	COG1719	4-vinyl reductase, 4VR
EQZ96_05375	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EQZ96_05385	COG1131	(ABC) transporter
EQZ96_05390	COG0537	adenosine 5'-monophosphoramidase activity
EQZ96_05400	COG0363	glucosamine-6-phosphate deaminase activity
EQZ96_05410	COG0825	malonyl-CoA metabolic process
EQZ96_05415	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EQZ96_05420	COG0439	Biotin carboxylase
EQZ96_05430	COG0556	nucleotide-excision repair
EQZ96_05450	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EQZ96_05460	COG0116	Belongs to the methyltransferase superfamily
EQZ96_05470	COG3599	regulation of cell shape
EQZ96_05475	COG4474	Belongs to the UPF0398 family
EQZ96_05480	COG3331	DNA recombination
EQZ96_05490	COG3935	DnaD domain protein
EQZ96_05495	COG0017	Asparaginyl-tRNA synthetase
EQZ96_05505	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EQZ96_05505	COG1199	ATP-dependent helicase activity
EQZ96_05525	COG1304	FMN binding
EQZ96_05535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQZ96_05540	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ96_05545	COG0706	membrane insertase activity
EQZ96_05560	COG0531	amino acid
EQZ96_05570	COG1705	Flagellar rod assembly protein muramidase FlgJ
EQZ96_05570	COG3942	CHAP domain
EQZ96_05580	COG5002	protein histidine kinase activity
EQZ96_05585	COG0745	RESPONSE REGULATOR receiver
EQZ96_05600	COG1484	DNA-dependent DNA replication
EQZ96_05610	COG0237	dephospho-CoA kinase activity
EQZ96_05615	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EQZ96_05620	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EQZ96_05620	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EQZ96_05625	COG0670	Belongs to the BI1 family
EQZ96_05630	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EQZ96_05640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQZ96_05645	COG1363	Peptidase, m42
EQZ96_05650	COG0572	uridine kinase
EQZ96_05655	COG5002	protein histidine kinase activity
EQZ96_05660	COG0745	RESPONSE REGULATOR receiver
EQZ96_05690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EQZ96_05695	COG0358	DNA primase activity
EQZ96_05700	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EQZ96_05705	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EQZ96_05715	COG0477	Major facilitator Superfamily
EQZ96_05720	COG3480	Lon protease (S16) C-terminal proteolytic domain
EQZ96_05725	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EQZ96_05730	COG0742	ribosomal rna small subunit methyltransferase
EQZ96_05735	COG4471	UPF0298 protein
EQZ96_05740	COG0772	Belongs to the SEDS family
EQZ96_05750	COG0483	inositol monophosphate 1-phosphatase activity
EQZ96_05755	COG4476	Belongs to the UPF0223 family
EQZ96_05760	COG0242	peptide deformylase activity
EQZ96_05795	COG1011	Hydrolase
EQZ96_05800	COG1597	lipid kinase activity
EQZ96_05805	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EQZ96_05810	COG1464	Belongs to the NlpA lipoprotein family
EQZ96_05815	COG0446	pyridine nucleotide-disulphide oxidoreductase
EQZ96_05825	COG3448	diguanylate cyclase activity
EQZ96_05825	COG4175	Glycine betaine
EQZ96_05840	COG1227	inorganic diphosphatase activity
EQZ96_05845	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EQZ96_05855	COG4974	Belongs to the 'phage' integrase family
EQZ96_05860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EQZ96_05865	COG0758	DNA mediated transformation
EQZ96_05870	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EQZ96_05880	COG4479	Belongs to the UPF0346 family
EQZ96_05890	COG2755	lipolytic protein G-D-S-L family
EQZ96_05895	COG1307	EDD domain protein, DegV family
EQZ96_05900	COG1307	EDD domain protein, DegV family
EQZ96_05905	COG2270	Major facilitator Superfamily
EQZ96_05920	COG3142	Participates in the control of copper homeostasis
EQZ96_05930	COG0196	riboflavin kinase activity
EQZ96_05940	COG1252	NADH dehydrogenase
EQZ96_05945	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EQZ96_05950	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EQZ96_05955	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EQZ96_05965	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EQZ96_05970	COG0195	Participates in both transcription termination and antitermination
EQZ96_05975	COG0779	Required for maturation of 30S ribosomal subunits
EQZ96_05990	COG1304	FMN binding
EQZ96_06010	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EQZ96_06015	COG0738	Major facilitator superfamily
EQZ96_06025	COG0287	Prephenate dehydrogenase
EQZ96_06030	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EQZ96_06035	COG4684	Psort location CytoplasmicMembrane, score
EQZ96_06040	COG0583	DNA-binding transcription factor activity
EQZ96_06055	COG1033	growth of symbiont in host cell
EQZ96_06055	COG2409	Drug exporters of the RND superfamily
EQZ96_06060	COG2409	Drug exporters of the RND superfamily
EQZ96_06060	COG1033	growth of symbiont in host cell
EQZ96_06080	COG1621	beta-fructofuranosidase activity
EQZ96_06090	COG0384	phenazine biosynthesis protein PhzF
EQZ96_06140	COG0456	acetyltransferase
EQZ96_06145	COG1846	Transcriptional regulator
EQZ96_06155	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EQZ96_06160	COG0656	L-ascorbic acid biosynthetic process
EQZ96_06175	COG4166	transmembrane transport
EQZ96_06225	COG2814	Major facilitator Superfamily
EQZ96_06230	COG2239	Acts as a magnesium transporter
EQZ96_06235	COG0564	pseudouridine synthase activity
EQZ96_06240	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EQZ96_06245	COG2357	RelA SpoT domain protein
EQZ96_06260	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EQZ96_06265	COG1518	maintenance of DNA repeat elements
EQZ96_06280	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EQZ96_06285	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EQZ96_06365	COG1940	carbohydrate kinase activity
EQZ96_06375	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ96_06405	COG0352	thiamine-phosphate diphosphorylase activity
EQZ96_06410	COG0351	phosphomethylpyrimidine kinase
EQZ96_06415	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EQZ96_06425	COG1464	Belongs to the NlpA lipoprotein family
EQZ96_06440	COG0436	Aminotransferase
EQZ96_06445	COG0277	FAD linked oxidase domain protein
EQZ96_06470	COG2801	Transposase and inactivated derivatives
EQZ96_06485	COG3321	synthase
EQZ96_06485	COG0604	alcohol dehydrogenase
EQZ96_06495	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EQZ96_06500	COG0277	FAD linked oxidase domain protein
EQZ96_06540	COG3201	nicotinamide mononucleotide transporter
EQZ96_06545	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EQZ96_06565	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EQZ96_06580	COG1473	amidohydrolase
EQZ96_06585	COG3527	Alpha-acetolactate decarboxylase
EQZ96_06590	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EQZ96_06595	COG0187	DNA topoisomerase II activity
EQZ96_06600	COG3118	belongs to the thioredoxin family
EQZ96_06620	COG1193	negative regulation of DNA recombination
EQZ96_06640	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EQZ96_06645	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EQZ96_06650	COG0544	peptidyl-prolyl cis-trans isomerase activity
EQZ96_06675	COG0268	Binds directly to 16S ribosomal RNA
EQZ96_06680	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EQZ96_06685	COG1466	dna polymerase III delta subunit
EQZ96_06700	COG3906	Belongs to the UPF0473 family
EQZ96_06720	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EQZ96_06725	COG1929	Belongs to the glycerate kinase type-1 family
EQZ96_06730	COG0513	Belongs to the DEAD box helicase family
EQZ96_06735	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EQZ96_06740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EQZ96_06745	COG1862	Preprotein translocase
EQZ96_06750	COG0343	queuine tRNA-ribosyltransferase activity
EQZ96_06785	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EQZ96_06790	COG2255	four-way junction helicase activity
EQZ96_06795	COG0632	four-way junction helicase activity
EQZ96_06800	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EQZ96_06805	COG0516	GMP reductase activity
EQZ96_06805	COG0517	IMP dehydrogenase activity
EQZ96_06825	COG1739	Uncharacterized protein family UPF0029
EQZ96_06830	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EQZ96_06835	COG0322	excinuclease ABC activity
EQZ96_06845	COG1668	transmembrane transport
EQZ96_06850	COG4152	abc transporter atp-binding protein
EQZ96_06860	COG1674	ftsk spoiiie
EQZ96_06870	COG0628	permease
EQZ96_06875	COG2706	6-phosphogluconolactonase activity
EQZ96_06895	COG0751	glycine-tRNA ligase activity
EQZ96_06900	COG0752	glycyl-tRNA synthetase alpha subunit
EQZ96_06910	COG1381	Involved in DNA repair and RecF pathway recombination
EQZ96_06915	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EQZ96_06920	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EQZ96_06925	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EQZ96_06930	COG1702	phosphate starvation-inducible protein PhoH
EQZ96_06935	COG1610	YqeY-like protein
EQZ96_06940	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EQZ96_06945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQZ96_06955	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EQZ96_06960	COG0124	histidyl-tRNA synthetase
EQZ96_06965	COG0860	N-Acetylmuramoyl-L-alanine amidase
EQZ96_06980	COG3425	synthase
EQZ96_06985	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EQZ96_07060	COG0006	proline dipeptidase activity
EQZ96_07065	COG1609	Transcriptional regulator
EQZ96_07080	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EQZ96_07085	COG1164	Oligoendopeptidase f
EQZ96_07095	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQZ96_07105	COG1447	Phosphotransferase system cellobiose-specific component IIA
EQZ96_07110	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQZ96_07115	COG2723	6-phospho-beta-galactosidase activity
EQZ96_07120	COG4862	establishment of competence for transformation
EQZ96_07125	COG1393	Belongs to the ArsC family
EQZ96_07130	COG3853	Toxic anion resistance protein (TelA)
EQZ96_07195	COG0561	phosphatase activity
EQZ96_07200	COG1970	mechanosensitive ion channel activity
EQZ96_07205	COG1428	Deoxynucleoside kinase
EQZ96_07215	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EQZ96_07220	COG1942	4-Oxalocrotonate Tautomerase
EQZ96_07225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQZ96_07235	COG0335	large ribosomal subunit rRNA binding
EQZ96_07240	COG0336	Belongs to the RNA methyltransferase TrmD family
EQZ96_07245	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EQZ96_07250	COG0588	phosphoglycerate mutase activity
EQZ96_07265	COG0228	four-way junction DNA binding
EQZ96_07280	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EQZ96_07290	COG0552	protein localization to endoplasmic reticulum
EQZ96_07295	COG1196	nuclear chromosome segregation
EQZ96_07300	COG0571	ribonuclease III activity
EQZ96_07305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EQZ96_07310	COG0416	fatty acid biosynthetic process
EQZ96_07315	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EQZ96_07325	COG0438	transferase activity, transferring glycosyl groups
EQZ96_07335	COG1461	Dihydroxyacetone kinase
EQZ96_07345	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EQZ96_07355	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EQZ96_07360	COG1162	GTPase activity
EQZ96_07365	COG0515	serine threonine protein kinase
EQZ96_07365	COG2815	serine threonine protein kinase
EQZ96_07370	COG0631	protein serine/threonine phosphatase activity
EQZ96_07375	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EQZ96_07375	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EQZ96_07380	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EQZ96_07385	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EQZ96_07390	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EQZ96_07435	COG2252	PERMEase
EQZ96_07440	COG0217	transcriptional regulatory protein
EQZ96_07445	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EQZ96_07465	COG3599	regulation of cell shape
EQZ96_07480	COG1799	cell septum assembly
EQZ96_07490	COG0849	cell division
EQZ96_07495	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EQZ96_07500	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EQZ96_07505	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EQZ96_07510	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EQZ96_07525	COG0275	rRNA processing
EQZ96_07530	COG2001	Belongs to the MraZ family
EQZ96_07540	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EQZ96_07545	COG2264	protein methyltransferase activity
EQZ96_07555	COG0833	amino acid
EQZ96_07570	COG0446	pyridine nucleotide-disulphide oxidoreductase
EQZ96_07585	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EQZ96_07590	COG0151	Belongs to the GarS family
EQZ96_07595	COG0138	bifunctional purine biosynthesis protein purh
EQZ96_07600	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EQZ96_07605	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EQZ96_07615	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EQZ96_07630	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EQZ96_07635	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EQZ96_07640	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EQZ96_07655	COG1126	abc transporter atp-binding protein
EQZ96_07660	COG0765	amino acid transport
EQZ96_07670	COG3338	carbonate dehydratase activity
EQZ96_07675	COG1792	Involved in formation and maintenance of cell shape
EQZ96_07680	COG1077	Cell shape determining protein MreB Mrl
EQZ96_07685	COG2003	Belongs to the UPF0758 family
EQZ96_07700	COG2190	(PTS) system
EQZ96_07700	COG1263	PTS System
EQZ96_07700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQZ96_07705	COG1307	EDD domain protein, DegV family
EQZ96_07710	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EQZ96_07715	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EQZ96_07720	COG0038	chloride channel
EQZ96_07730	COG4120	Belongs to the binding-protein-dependent transport system permease family
EQZ96_07740	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EQZ96_07745	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EQZ96_07750	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EQZ96_07770	COG0741	lytic transglycosylase activity
EQZ96_07780	COG0400	carboxylic ester hydrolase activity
EQZ96_07785	COG0346	lactoylglutathione lyase activity
EQZ96_07790	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EQZ96_07800	COG0494	nUDIX hydrolase
EQZ96_07820	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EQZ96_07825	COG1388	LysM domain
EQZ96_07825	COG1705	Flagellar rod assembly protein muramidase FlgJ
EQZ96_07830	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EQZ96_07835	COG4988	ABC transporter
EQZ96_07840	COG1294	oxidase, subunit
EQZ96_07845	COG1271	oxidase subunit
EQZ96_07850	COG4684	Psort location CytoplasmicMembrane, score
EQZ96_07965	COG1098	S1 RNA binding domain
EQZ96_07970	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EQZ96_07975	COG0586	Pfam SNARE associated Golgi protein
EQZ96_07985	COG0194	GDP metabolic process
EQZ96_07995	COG0497	DNA recombination
EQZ96_08000	COG1438	arginine binding
EQZ96_08005	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EQZ96_08010	COG0142	geranyltranstransferase activity
EQZ96_08020	COG1570	exodeoxyribonuclease VII activity
EQZ96_08025	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EQZ96_08030	COG4720	Psort location CytoplasmicMembrane, score
EQZ96_08045	COG1136	(ABC) transporter
EQZ96_08050	COG0577	efflux transmembrane transporter activity
EQZ96_08060	COG0776	regulation of translation
EQZ96_08065	COG0363	glucosamine-6-phosphate deaminase activity
EQZ96_08075	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EQZ96_08140	COG2801	Transposase and inactivated derivatives
EQZ96_08175	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EQZ96_08180	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EQZ96_08190	COG1323	Belongs to the UPF0348 family
EQZ96_08195	COG2226	methyltransferase
EQZ96_08200	COG0799	negative regulation of ribosome biogenesis
EQZ96_08205	COG1713	HD superfamily hydrolase involved in NAD metabolism
EQZ96_08210	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EQZ96_08220	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EQZ96_08225	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EQZ96_08230	COG1181	Belongs to the D-alanine--D-alanine ligase family
EQZ96_08240	COG0531	amino acid
EQZ96_08245	COG0459	protein refolding
EQZ96_08250	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EQZ96_08255	COG0488	(ABC) transporter
EQZ96_08275	COG0285	dihydrofolate synthase activity
EQZ96_08285	COG0525	valine-tRNA ligase activity
EQZ96_08320	COG1272	protein, Hemolysin III
EQZ96_08435	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EQZ96_08445	COG5506	Protein of unknown function (DUF1694)
EQZ96_08455	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EQZ96_08490	COG2137	regulation of response to DNA damage stimulus
EQZ96_08495	COG0704	Plays a role in the regulation of phosphate uptake
EQZ96_08500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EQZ96_08505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EQZ96_08510	COG0581	inorganic phosphate transmembrane transporter activity
EQZ96_08515	COG0573	inorganic phosphate transmembrane transporter activity
EQZ96_08520	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EQZ96_08545	COG4166	transmembrane transport
EQZ96_08550	COG0647	UMP catabolic process
EQZ96_08555	COG4470	Protein conserved in bacteria
EQZ96_08560	COG0737	Belongs to the 5'-nucleotidase family
EQZ96_08580	COG4948	Mandelate Racemase Muconate Lactonizing
EQZ96_08585	COG0596	Alpha beta hydrolase
EQZ96_08590	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EQZ96_08595	COG1169	isochorismate synthase
EQZ96_08600	COG0778	Nitroreductase
EQZ96_08605	COG1132	(ABC) transporter
EQZ96_08615	COG1472	Belongs to the glycosyl hydrolase 3 family
EQZ96_08620	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EQZ96_08625	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EQZ96_08650	COG0174	glutamine synthetase
EQZ96_08655	COG0789	Transcriptional regulator
EQZ96_08660	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EQZ96_08665	COG0584	glycerophosphoryl diester phosphodiesterase
EQZ96_08685	COG3942	CHAP domain
EQZ96_08690	COG5632	N-Acetylmuramoyl-L-alanine amidase
EQZ96_08690	COG3409	Peptidoglycan-binding domain 1 protein
EQZ96_08700	COG1940	carbohydrate kinase activity
EQZ96_08715	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EQZ96_08720	COG0768	penicillin binding
EQZ96_08730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EQZ96_08735	COG0514	ATP-dependent DNA helicase (RecQ)
EQZ96_08740	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EQZ96_08745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQZ96_08745	COG0072	phenylalanine-tRNA ligase activity
EQZ96_08750	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EQZ96_08755	COG1733	regulation of RNA biosynthetic process
EQZ96_08765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EQZ96_08785	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EQZ96_08790	COG0653	protein targeting
EQZ96_08800	COG4956	integral membrane protein (PIN domain superfamily)
EQZ96_08810	COG0756	dUTP diphosphatase activity
EQZ96_08820	COG0791	NLP P60 protein
EQZ96_08825	COG1388	LysM domain
EQZ96_08825	COG3942	CHAP domain
EQZ96_08835	COG3527	Alpha-acetolactate decarboxylase
EQZ96_08840	COG0028	Belongs to the TPP enzyme family
EQZ96_08845	COG0039	L-malate dehydrogenase activity
EQZ96_08865	COG1914	H( )-stimulated, divalent metal cation uptake system
EQZ96_08875	COG1263	PTS System
EQZ96_08875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQZ96_08890	COG0740	serine-type endopeptidase activity
EQZ96_08895	COG1481	regulation of sporulation
EQZ96_08900	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EQZ96_08905	COG1660	Displays ATPase and GTPase activities
EQZ96_08915	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EQZ96_08920	COG2814	Major facilitator Superfamily
EQZ96_08930	COG0671	phosphoesterase, PA-phosphatase related
EQZ96_08955	COG1573	uracil-dna glycosylase
EQZ96_08965	COG0028	Belongs to the TPP enzyme family
EQZ96_08980	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EQZ96_08985	COG0101	tRNA pseudouridine synthase activity
EQZ96_08995	COG1122	ATPase activity
EQZ96_09000	COG1122	ATPase activity
EQZ96_09010	COG1252	NADH dehydrogenase
EQZ96_09015	COG0803	Belongs to the bacterial solute-binding protein 9 family
EQZ96_09020	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EQZ96_09025	COG1121	(ABC) transporter
EQZ96_09035	COG0222	ribosome binding
EQZ96_09040	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EQZ96_09045	COG0081	regulation of translation
EQZ96_09050	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EQZ96_09055	COG0250	Participates in transcription elongation, termination and antitermination
EQZ96_09060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EQZ96_09075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EQZ96_09080	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EQZ96_09085	COG1854	S-ribosylhomocysteine lyase activity
EQZ96_09090	COG1464	Belongs to the NlpA lipoprotein family
EQZ96_09095	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EQZ96_09100	COG0626	cystathionine gamma-synthase activity
EQZ96_09105	COG0215	cysteine-tRNA ligase activity
EQZ96_09110	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EQZ96_09115	COG0039	L-malate dehydrogenase activity
EQZ96_09120	COG0471	metal ion transport
EQZ96_09125	COG1053	succinate dehydrogenase
EQZ96_09130	COG0114	fumarate hydratase activity
EQZ96_09135	COG0583	DNA-binding transcription factor activity
EQZ96_09160	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EQZ96_09175	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EQZ96_09200	COG0203	ribosomal protein L17
EQZ96_09205	COG0202	RNA polymerase activity
EQZ96_09210	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EQZ96_09220	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EQZ96_09225	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EQZ96_09240	COG0200	Binds to the 23S rRNA
EQZ96_09245	COG1841	ribosomal large subunit assembly
EQZ96_09250	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EQZ96_09255	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EQZ96_09260	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EQZ96_09265	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EQZ96_09270	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EQZ96_09275	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EQZ96_09280	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EQZ96_09290	COG0255	Belongs to the universal ribosomal protein uL29 family
EQZ96_09295	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EQZ96_09300	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EQZ96_09305	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EQZ96_09310	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EQZ96_09315	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EQZ96_09320	COG0089	rRNA binding
EQZ96_09330	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EQZ96_09335	COG0051	transcription antitermination factor activity, RNA binding
EQZ96_09340	COG0142	geranyltranstransferase activity
EQZ96_09345	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EQZ96_09355	COG0456	acetyltransferase
EQZ96_09360	COG1214	PFAM Peptidase M22, glycoprotease
EQZ96_09365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EQZ96_09385	COG3870	Protein conserved in bacteria
EQZ96_09390	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EQZ96_09415	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EQZ96_09425	COG0590	tRNA wobble adenosine to inosine editing
EQZ96_09430	COG2813	Specifically methylates the guanine in position
EQZ96_09440	COG2807	transmembrane transport
EQZ96_09450	COG3620	sequence-specific DNA binding
EQZ96_09490	COG0500	methyltransferase
EQZ96_09495	COG1309	transcriptional regulator
EQZ96_09510	COG1979	alcohol dehydrogenase
EQZ96_09535	COG0542	response to heat
EQZ96_09540	COG4463	regulation of RNA biosynthetic process
EQZ96_09565	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EQZ96_09570	COG1428	Deoxynucleoside kinase
EQZ96_09575	COG1876	peptidase activity
EQZ96_09580	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EQZ96_09585	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EQZ96_09590	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EQZ96_09595	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EQZ96_09600	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EQZ96_09605	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EQZ96_09610	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EQZ96_09615	COG0356	it plays a direct role in the translocation of protons across the membrane
EQZ96_09620	COG2233	PERMEase
EQZ96_09630	COG0702	epimerase
EQZ96_09635	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EQZ96_09640	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EQZ96_09645	COG0009	L-threonylcarbamoyladenylate synthase
EQZ96_09650	COG2890	protein-(glutamine-N5) methyltransferase activity
EQZ96_09655	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EQZ96_09660	COG1435	thymidine kinase activity
EQZ96_09670	COG3442	glutamine amidotransferase
EQZ96_09675	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EQZ96_09680	COG1482	cell wall glycoprotein biosynthetic process
EQZ96_09690	COG0110	maltose O-acetyltransferase activity
EQZ96_09715	COG1132	(ABC) transporter
EQZ96_09720	COG1132	(ABC) transporter
EQZ96_09740	COG0588	phosphoglycerate mutase activity
EQZ96_09760	COG0708	Exodeoxyribonuclease III
EQZ96_09770	COG1454	alcohol dehydrogenase
EQZ96_09770	COG1012	belongs to the aldehyde dehydrogenase family
EQZ96_09775	COG3590	peptidase
EQZ96_09815	COG5039	Polysaccharide pyruvyl transferase
EQZ96_09845	COG1442	glycosyl transferase family 8
EQZ96_09845	COG1216	Glycosyl transferase, family 2
EQZ96_09880	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EQZ96_09885	COG2188	Transcriptional regulator
EQZ96_09895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EQZ96_09900	COG2814	Major facilitator Superfamily
EQZ96_09905	COG1418	mRNA catabolic process
EQZ96_09920	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EQZ96_09930	COG1215	transferase activity, transferring glycosyl groups
EQZ96_09965	COG0765	amino acid transport
EQZ96_09995	COG0656	L-ascorbic acid biosynthetic process
EQZ96_10000	COG2160	L-arabinose isomerase activity
EQZ96_10020	COG3940	Belongs to the glycosyl hydrolase 43 family
EQZ96_10035	COG0534	Mate efflux family protein
EQZ96_10040	COG0488	(ABC) transporter
EQZ96_10050	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EQZ96_10055	COG1121	(ABC) transporter
EQZ96_10065	COG1846	Transcriptional regulator
EQZ96_10070	COG2755	lipolytic protein G-D-S-L family
EQZ96_10070	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EQZ96_10075	COG3091	SprT-like family
EQZ96_10120	COG4975	Glucose uptake
EQZ96_10125	COG0477	Major facilitator Superfamily
EQZ96_10130	COG3104	oligopeptide transport
EQZ96_10190	COG1686	Belongs to the peptidase S11 family
EQZ96_10200	COG0745	RESPONSE REGULATOR receiver
EQZ96_10210	COG0012	GTP binding
EQZ96_10215	COG4481	Protein conserved in bacteria
EQZ96_10220	COG1475	DNA binding
EQZ96_10225	COG1192	Involved in chromosome partitioning
EQZ96_10230	COG0357	Ribosomal RNA small subunit methyltransferase G
EQZ96_10240	COG1194	a g-specific adenine glycosylase
EQZ96_10245	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EQZ96_10285	COG5002	protein histidine kinase activity
EQZ96_10290	COG0745	RESPONSE REGULATOR receiver
EQZ96_10305	COG0318	PFAM AMP-dependent synthetase and ligase
EQZ96_10310	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EQZ96_10315	COG2050	protein possibly involved in aromatic compounds catabolism
EQZ96_10320	COG1335	isochorismatase
EQZ96_10330	COG2226	methyltransferase
EQZ96_10340	COG4443	Transcriptional Coactivator p15 (PC4)
EQZ96_10345	COG0252	asparaginase activity
EQZ96_10350	COG0531	amino acid
EQZ96_10355	COG1113	amino acid transport
EQZ96_10360	COG0531	amino acid
EQZ96_10375	COG4975	Glucose uptake
EQZ96_10380	COG0477	Major facilitator Superfamily
EQZ96_10390	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EQZ96_10395	COG2267	carboxylic ester hydrolase activity
EQZ96_10400	COG4166	transmembrane transport
EQZ96_10405	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EQZ96_10415	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EQZ96_10425	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EQZ96_10445	COG0531	amino acid
EQZ96_10470	COG2855	membrane
EQZ96_10480	COG3620	sequence-specific DNA binding
EQZ96_10485	COG2855	membrane
EQZ96_10495	COG0454	-acetyltransferase
EQZ96_10495	COG0456	acetyltransferase
EQZ96_10500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EQZ96_10525	COG1113	amino acid transport
EQZ96_10555	COG0628	permease
EQZ96_10565	COG0392	lysyltransferase activity
EQZ96_10565	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EQZ96_10585	COG2856	Zn peptidase
EQZ96_10600	COG1254	Belongs to the acylphosphatase family
EQZ96_10605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQZ96_10610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQZ96_10615	COG0765	amino acid transport
EQZ96_10620	COG1126	abc transporter atp-binding protein
EQZ96_10630	COG1131	(ABC) transporter
EQZ96_10640	COG0390	transport system, permease component
EQZ96_10645	COG4619	ABC transporter
EQZ96_10655	COG0656	L-ascorbic acid biosynthetic process
EQZ96_10665	COG1132	(ABC) transporter
EQZ96_10670	COG1846	Transcriptional regulator
EQZ96_10690	COG1744	ABC transporter substrate-binding protein PnrA-like
EQZ96_10705	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EQZ96_10720	COG0789	Transcriptional regulator
EQZ96_10730	COG1131	(ABC) transporter
EQZ96_10750	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EQZ96_10755	COG0505	Belongs to the CarA family
EQZ96_10760	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EQZ96_10765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EQZ96_10775	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EQZ96_10780	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EQZ96_10785	COG0165	Argininosuccinate lyase
EQZ96_10790	COG0137	argininosuccinate synthase activity
EQZ96_10795	COG1744	ABC transporter substrate-binding protein PnrA-like
EQZ96_10810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EQZ96_10835	COG0697	spore germination
EQZ96_10890	COG1476	TRANSCRIPTIONal
EQZ96_10905	COG1881	PFAM PEBP family protein
EQZ96_10945	COG2252	PERMEase
EQZ96_10950	COG3152	Membrane
EQZ96_10970	COG0328	RNA-DNA hybrid ribonuclease activity
EQZ96_10980	COG0561	phosphatase activity
EQZ96_10985	COG1033	growth of symbiont in host cell
EQZ96_10985	COG2409	Drug exporters of the RND superfamily
EQZ96_10990	COG0577	efflux transmembrane transporter activity
EQZ96_10995	COG1136	(ABC) transporter
EQZ96_11005	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EQZ96_11010	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EQZ96_11020	COG0446	pyridine nucleotide-disulphide oxidoreductase
EQZ96_11030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQZ96_11050	COG1113	amino acid transport
EQZ96_11055	COG0569	domain protein
EQZ96_11070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQZ96_11080	COG1120	ATPase activity
EQZ96_11090	COG0706	membrane insertase activity
EQZ96_11095	COG0594	ribonuclease P activity
EQZ96_11100	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EQZ96_11125	COG2801	Transposase and inactivated derivatives
EQZ96_11150	COG2261	transglycosylase associated protein
EQZ96_11180	COG0783	Belongs to the Dps family
EQZ96_11185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EQZ96_11255	COG2801	Transposase and inactivated derivatives
EQZ96_11260	COG1028	Short-chain dehydrogenase reductase Sdr
EQZ96_11275	COG5039	Polysaccharide pyruvyl transferase
EQZ96_11280	COG2814	Major facilitator Superfamily
EQZ96_11285	COG0640	Transcriptional regulator
EQZ96_11295	COG3118	belongs to the thioredoxin family
EQZ96_11300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQZ96_11305	COG1794	racemase activity, acting on amino acids and derivatives
EQZ96_11310	COG0492	ferredoxin-NADP+ reductase activity
EQZ96_11320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQZ96_11340	COG1063	alcohol dehydrogenase
EQZ96_11360	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EQZ96_11380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EQZ96_11420	COG2855	membrane