locus-tag	class	description
G4V46_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G4V46_00010	COG0230	Belongs to the bacterial ribosomal protein bL34 family
G4V46_00015	COG0594	ribonuclease P activity
G4V46_00030	COG1120	ATPase activity
G4V46_00035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4V46_00040	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
G4V46_00065	COG0569	domain protein
G4V46_00070	COG1113	amino acid transport
G4V46_00115	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
G4V46_00120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G4V46_00125	COG0561	phosphatase activity
G4V46_00135	COG0328	RNA-DNA hybrid ribonuclease activity
G4V46_00160	COG2252	PERMEase
G4V46_00165	COG0431	NADPH-dependent FMN reductase
G4V46_00170	COG1846	Transcriptional regulator
G4V46_00185	COG0149	triose-phosphate isomerase activity
G4V46_00225	COG1125	glycine betaine transport
G4V46_00225	COG0517	IMP dehydrogenase activity
G4V46_00230	COG1174	glycine betaine transport
G4V46_00240	COG1464	Belongs to the NlpA lipoprotein family
G4V46_00245	COG1506	peptidase
G4V46_00245	COG0823	Involved in the tonB-independent uptake of proteins
G4V46_00245	COG4946	Tricorn protease homolog
G4V46_00310	COG1744	ABC transporter substrate-binding protein PnrA-like
G4V46_00330	COG1388	LysM domain
G4V46_00350	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G4V46_00355	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G4V46_00365	COG0697	spore germination
G4V46_00385	COG1846	Transcriptional regulator
G4V46_00390	COG1132	(ABC) transporter
G4V46_00400	COG0656	L-ascorbic acid biosynthetic process
G4V46_00410	COG4619	ABC transporter
G4V46_00415	COG0390	transport system, permease component
G4V46_00420	COG1126	abc transporter atp-binding protein
G4V46_00425	COG0765	amino acid transport
G4V46_00430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4V46_00435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4V46_00440	COG1254	Belongs to the acylphosphatase family
G4V46_00455	COG2801	Transposase and inactivated derivatives
G4V46_00470	COG2801	Transposase and inactivated derivatives
G4V46_00480	COG0392	lysyltransferase activity
G4V46_00480	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
G4V46_00490	COG0628	permease
G4V46_00510	COG2801	Transposase and inactivated derivatives
G4V46_00530	COG1113	amino acid transport
G4V46_00555	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G4V46_00565	COG2855	membrane
G4V46_00585	COG1228	amidohydrolase
G4V46_00590	COG0531	amino acid
G4V46_00600	COG4975	Glucose uptake
G4V46_00615	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G4V46_00625	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G4V46_00635	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G4V46_00640	COG1063	alcohol dehydrogenase
G4V46_00645	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G4V46_00650	COG0477	Major facilitator Superfamily
G4V46_00660	COG0531	amino acid
G4V46_00700	COG1113	amino acid transport
G4V46_00705	COG0531	amino acid
G4V46_00710	COG0252	asparaginase activity
G4V46_00715	COG4443	Transcriptional Coactivator p15 (PC4)
G4V46_00725	COG2226	methyltransferase
G4V46_00730	COG1335	isochorismatase
G4V46_00735	COG2050	protein possibly involved in aromatic compounds catabolism
G4V46_00740	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G4V46_00745	COG0318	PFAM AMP-dependent synthetase and ligase
G4V46_00760	COG0745	RESPONSE REGULATOR receiver
G4V46_00765	COG5002	protein histidine kinase activity
G4V46_00770	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
G4V46_00785	COG2207	Transcriptional regulator
G4V46_00795	COG1511	domain protein
G4V46_00810	COG1194	a g-specific adenine glycosylase
G4V46_00815	COG1957	nucleoside hydrolase
G4V46_00820	COG0357	Ribosomal RNA small subunit methyltransferase G
G4V46_00825	COG1192	Involved in chromosome partitioning
G4V46_00830	COG1475	DNA binding
G4V46_00835	COG4481	Protein conserved in bacteria
G4V46_00840	COG0012	GTP binding
G4V46_00850	COG0745	RESPONSE REGULATOR receiver
G4V46_00860	COG1686	Belongs to the peptidase S11 family
G4V46_00910	COG3104	oligopeptide transport
G4V46_00915	COG0477	Major facilitator Superfamily
G4V46_00920	COG3479	Phenolic acid decarboxylase
G4V46_00955	COG3091	SprT-like family
G4V46_00960	COG1979	alcohol dehydrogenase
G4V46_00965	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G4V46_00965	COG2755	lipolytic protein G-D-S-L family
G4V46_00970	COG1846	Transcriptional regulator
G4V46_00980	COG1121	(ABC) transporter
G4V46_00990	COG0488	(ABC) transporter
G4V46_00995	COG0534	Mate efflux family protein
G4V46_01065	COG1418	mRNA catabolic process
G4V46_01070	COG2814	Major facilitator Superfamily
G4V46_01095	COG2188	Transcriptional regulator
G4V46_01100	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
G4V46_01105	COG5039	Polysaccharide pyruvyl transferase
G4V46_01140	COG3590	peptidase
G4V46_01150	COG1012	belongs to the aldehyde dehydrogenase family
G4V46_01150	COG1454	alcohol dehydrogenase
G4V46_01165	COG0708	Exodeoxyribonuclease III
G4V46_01170	COG1131	(ABC) transporter
G4V46_01190	COG0588	phosphoglycerate mutase activity
G4V46_01195	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G4V46_01205	COG1132	(ABC) transporter
G4V46_01210	COG1132	(ABC) transporter
G4V46_01225	COG2801	Transposase and inactivated derivatives
G4V46_01240	COG2801	Transposase and inactivated derivatives
G4V46_01265	COG1482	cell wall glycoprotein biosynthetic process
G4V46_01280	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G4V46_01285	COG3442	glutamine amidotransferase
G4V46_01305	COG1435	thymidine kinase activity
G4V46_01315	COG2890	protein-(glutamine-N5) methyltransferase activity
G4V46_01320	COG0009	L-threonylcarbamoyladenylate synthase
G4V46_01325	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G4V46_01330	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G4V46_01335	COG0702	epimerase
G4V46_01340	COG2233	PERMEase
G4V46_01345	COG0356	it plays a direct role in the translocation of protons across the membrane
G4V46_01350	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G4V46_01355	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G4V46_01360	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G4V46_01365	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G4V46_01370	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G4V46_01375	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G4V46_01380	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G4V46_01385	COG1876	peptidase activity
G4V46_01390	COG1428	Deoxynucleoside kinase
G4V46_01395	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G4V46_01400	COG1686	Belongs to the peptidase S11 family
G4V46_01425	COG4463	regulation of RNA biosynthetic process
G4V46_01430	COG0542	response to heat
G4V46_01435	COG0085	RNA polymerase activity
G4V46_01445	COG1979	alcohol dehydrogenase
G4V46_01465	COG0500	methyltransferase
G4V46_01500	COG2807	transmembrane transport
G4V46_01510	COG2813	Specifically methylates the guanine in position
G4V46_01525	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G4V46_01535	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G4V46_01550	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G4V46_01555	COG3870	Protein conserved in bacteria
G4V46_01575	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G4V46_01595	COG2801	Transposase and inactivated derivatives
G4V46_01610	COG1214	PFAM Peptidase M22, glycoprotease
G4V46_01625	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G4V46_01635	COG0051	transcription antitermination factor activity, RNA binding
G4V46_01640	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G4V46_01650	COG0089	rRNA binding
G4V46_01655	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G4V46_01660	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G4V46_01665	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G4V46_01670	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G4V46_01675	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G4V46_01680	COG0255	Belongs to the universal ribosomal protein uL29 family
G4V46_01690	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G4V46_01695	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G4V46_01700	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G4V46_01705	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G4V46_01710	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G4V46_01715	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G4V46_01720	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G4V46_01725	COG1841	ribosomal large subunit assembly
G4V46_01730	COG0200	Binds to the 23S rRNA
G4V46_01745	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G4V46_01750	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G4V46_01755	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G4V46_01760	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G4V46_01765	COG0202	RNA polymerase activity
G4V46_01770	COG0203	ribosomal protein L17
G4V46_01795	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G4V46_01810	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G4V46_01820	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G4V46_01835	COG0215	cysteine-tRNA ligase activity
G4V46_01845	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G4V46_01850	COG1464	Belongs to the NlpA lipoprotein family
G4V46_01855	COG1854	S-ribosylhomocysteine lyase activity
G4V46_01860	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
G4V46_01865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G4V46_01880	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G4V46_01885	COG0250	Participates in transcription elongation, termination and antitermination
G4V46_01890	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G4V46_01895	COG0081	regulation of translation
G4V46_01900	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G4V46_01905	COG0222	ribosome binding
G4V46_01915	COG1121	(ABC) transporter
G4V46_01920	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G4V46_01925	COG0803	Belongs to the bacterial solute-binding protein 9 family
G4V46_01930	COG1252	NADH dehydrogenase
G4V46_01940	COG1122	ATPase activity
G4V46_01945	COG1122	ATPase activity
G4V46_01955	COG0101	tRNA pseudouridine synthase activity
G4V46_01960	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G4V46_01980	COG2814	Major facilitator Superfamily
G4V46_01990	COG0028	Belongs to the TPP enzyme family
G4V46_01995	COG1573	uracil-dna glycosylase
G4V46_02005	COG0366	Alpha amylase catalytic
G4V46_02020	COG0671	phosphoesterase, PA-phosphatase related
G4V46_02035	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G4V46_02050	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G4V46_02055	COG1481	regulation of sporulation
G4V46_02060	COG0740	serine-type endopeptidase activity
G4V46_02075	COG2190	(PTS) system
G4V46_02075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4V46_02075	COG1263	PTS System
G4V46_02085	COG1914	H( )-stimulated, divalent metal cation uptake system
G4V46_02105	COG2514	catechol 2,3-dioxygenase activity
G4V46_02110	COG2801	Transposase and inactivated derivatives
G4V46_02125	COG1215	transferase activity, transferring glycosyl groups
G4V46_02140	COG0039	L-malate dehydrogenase activity
G4V46_02145	COG0028	Belongs to the TPP enzyme family
G4V46_02150	COG3527	Alpha-acetolactate decarboxylase
G4V46_02160	COG1388	LysM domain
G4V46_02160	COG0791	NLP P60 protein
G4V46_02175	COG0756	dUTP diphosphatase activity
G4V46_02185	COG4956	integral membrane protein (PIN domain superfamily)
G4V46_02195	COG0653	protein targeting
G4V46_02200	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
G4V46_02210	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
G4V46_02240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G4V46_02265	COG1733	regulation of RNA biosynthetic process
G4V46_02270	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G4V46_02275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G4V46_02275	COG0072	phenylalanine-tRNA ligase activity
G4V46_02280	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G4V46_02285	COG0514	ATP-dependent DNA helicase (RecQ)
G4V46_02290	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G4V46_02305	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G4V46_02320	COG1940	carbohydrate kinase activity
G4V46_02330	COG4942	peptidase
G4V46_02335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G4V46_02350	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G4V46_02355	COG0789	Transcriptional regulator
G4V46_02360	COG0174	glutamine synthetase
G4V46_02385	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G4V46_02390	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G4V46_02425	COG1396	sequence-specific DNA binding
G4V46_02660	COG1523	belongs to the glycosyl hydrolase 13 family
G4V46_02670	COG1472	Belongs to the glycosyl hydrolase 3 family
G4V46_02700	COG2801	Transposase and inactivated derivatives
G4V46_02710	COG1132	(ABC) transporter
G4V46_02715	COG1169	isochorismate synthase
G4V46_02720	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
G4V46_02725	COG0596	Alpha beta hydrolase
G4V46_02730	COG4948	Mandelate Racemase Muconate Lactonizing
G4V46_02735	COG0006	proline dipeptidase activity
G4V46_02755	COG4470	Protein conserved in bacteria
G4V46_02760	COG0647	UMP catabolic process
G4V46_02765	COG4166	transmembrane transport
G4V46_02770	COG0673	inositol 2-dehydrogenase activity
G4V46_02775	COG1957	nucleoside hydrolase
G4V46_02795	COG0573	inorganic phosphate transmembrane transporter activity
G4V46_02800	COG0581	inorganic phosphate transmembrane transporter activity
G4V46_02805	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G4V46_02810	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G4V46_02815	COG0704	Plays a role in the regulation of phosphate uptake
G4V46_02820	COG2137	regulation of response to DNA damage stimulus
G4V46_02835	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G4V46_02850	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G4V46_02880	COG1272	protein, Hemolysin III
G4V46_02895	COG0525	valine-tRNA ligase activity
G4V46_02900	COG0285	dihydrofolate synthase activity
G4V46_02915	COG0488	(ABC) transporter
G4V46_02920	COG2814	Major facilitator Superfamily
G4V46_02930	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G4V46_02935	COG0459	protein refolding
G4V46_02940	COG0531	amino acid
G4V46_02950	COG1181	Belongs to the D-alanine--D-alanine ligase family
G4V46_02955	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
G4V46_02960	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
G4V46_02970	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G4V46_02975	COG1713	HD superfamily hydrolase involved in NAD metabolism
G4V46_02980	COG0799	negative regulation of ribosome biogenesis
G4V46_02985	COG2226	methyltransferase
G4V46_02990	COG1323	Belongs to the UPF0348 family
G4V46_03000	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G4V46_03005	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G4V46_03030	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G4V46_03035	COG0363	glucosamine-6-phosphate deaminase activity
G4V46_03050	COG0577	efflux transmembrane transporter activity
G4V46_03055	COG1136	(ABC) transporter
G4V46_03070	COG4720	Psort location CytoplasmicMembrane, score
G4V46_03075	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G4V46_03090	COG0142	geranyltranstransferase activity
G4V46_03095	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
G4V46_03100	COG1438	arginine binding
G4V46_03105	COG0497	DNA recombination
G4V46_03115	COG0194	GDP metabolic process
G4V46_03120	COG1758	RNA polymerase activity
G4V46_03125	COG0586	Pfam SNARE associated Golgi protein
G4V46_03135	COG1098	S1 RNA binding domain
G4V46_03245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G4V46_03250	COG4684	Psort location CytoplasmicMembrane, score
G4V46_03255	COG1271	oxidase subunit
G4V46_03260	COG1294	oxidase, subunit
G4V46_03265	COG4988	ABC transporter
G4V46_03270	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
G4V46_03275	COG1705	Flagellar rod assembly protein muramidase FlgJ
G4V46_03280	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G4V46_03320	COG1278	Cold shock
G4V46_03325	COG0494	nUDIX hydrolase
G4V46_03335	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G4V46_03340	COG0346	lactoylglutathione lyase activity
G4V46_03345	COG0400	carboxylic ester hydrolase activity
G4V46_03355	COG0741	lytic transglycosylase activity
G4V46_03375	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G4V46_03380	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G4V46_03395	COG4120	Belongs to the binding-protein-dependent transport system permease family
G4V46_03405	COG0038	chloride channel
G4V46_03410	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G4V46_03415	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G4V46_03420	COG1307	EDD domain protein, DegV family
G4V46_03425	COG1263	PTS System
G4V46_03425	COG2190	(PTS) system
G4V46_03425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4V46_03440	COG2003	Belongs to the UPF0758 family
G4V46_03445	COG1077	Cell shape determining protein MreB Mrl
G4V46_03465	COG0765	amino acid transport
G4V46_03470	COG1126	abc transporter atp-binding protein
G4V46_03480	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G4V46_03480	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G4V46_03485	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G4V46_03490	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G4V46_03500	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G4V46_03505	COG0047	phosphoribosylformylglycinamidine synthase activity
G4V46_03510	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G4V46_03525	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G4V46_03530	COG0138	bifunctional purine biosynthesis protein purh
G4V46_03535	COG0151	Belongs to the GarS family
G4V46_03540	COG2759	Belongs to the formate--tetrahydrofolate ligase family
G4V46_03555	COG0833	amino acid
G4V46_03565	COG2264	protein methyltransferase activity
G4V46_03570	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G4V46_03580	COG2001	Belongs to the MraZ family
G4V46_03585	COG0275	rRNA processing
G4V46_03600	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G4V46_03605	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G4V46_03610	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G4V46_03615	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G4V46_03620	COG0849	cell division
G4V46_03625	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G4V46_03630	COG1799	cell septum assembly
G4V46_03645	COG3599	regulation of cell shape
G4V46_03655	COG0406	alpha-ribazole phosphatase activity
G4V46_03665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G4V46_03670	COG0217	transcriptional regulatory protein
G4V46_03675	COG2252	PERMEase
G4V46_03680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G4V46_03725	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G4V46_03750	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G4V46_03755	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G4V46_03760	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G4V46_03760	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G4V46_03770	COG2815	serine threonine protein kinase
G4V46_03770	COG0515	serine threonine protein kinase
G4V46_03775	COG1162	GTPase activity
G4V46_03780	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G4V46_03785	COG1564	THIamine pyrophosphokinase
G4V46_03790	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G4V46_03800	COG1461	Dihydroxyacetone kinase
G4V46_03820	COG2211	Major facilitator Superfamily
G4V46_03825	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G4V46_03830	COG0416	fatty acid biosynthetic process
G4V46_03835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4V46_03840	COG0571	ribonuclease III activity
G4V46_03845	COG1196	nuclear chromosome segregation
G4V46_03850	COG0552	protein localization to endoplasmic reticulum
G4V46_03855	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
G4V46_03860	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G4V46_03875	COG0228	four-way junction DNA binding
G4V46_03885	COG0588	phosphoglycerate mutase activity
G4V46_03890	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G4V46_03895	COG0336	Belongs to the RNA methyltransferase TrmD family
G4V46_03910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4V46_03915	COG1942	4-Oxalocrotonate Tautomerase
G4V46_03930	COG1428	Deoxynucleoside kinase
G4V46_03935	COG1970	mechanosensitive ion channel activity
G4V46_03940	COG0561	phosphatase activity
G4V46_03975	COG4974	Belongs to the 'phage' integrase family
G4V46_04055	COG3723	Recombinational DNA repair protein, rece pathway
G4V46_04335	COG3853	Toxic anion resistance protein (TelA)
G4V46_04340	COG1393	Belongs to the ArsC family
G4V46_04355	COG2801	Transposase and inactivated derivatives
G4V46_04385	COG1164	Oligoendopeptidase f
G4V46_04390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G4V46_04405	COG1609	Transcriptional regulator
G4V46_04410	COG0006	proline dipeptidase activity
G4V46_04490	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G4V46_04495	COG3425	synthase
G4V46_04520	COG0124	histidyl-tRNA synthetase
G4V46_04525	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G4V46_04535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4V46_04540	COG0828	Belongs to the bacterial ribosomal protein bS21 family
G4V46_04545	COG1610	YqeY-like protein
G4V46_04550	COG1702	phosphate starvation-inducible protein PhoH
G4V46_04555	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G4V46_04560	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G4V46_04565	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G4V46_04570	COG1381	Involved in DNA repair and RecF pathway recombination
G4V46_04580	COG0752	glycyl-tRNA synthetase alpha subunit
G4V46_04585	COG0751	glycine-tRNA ligase activity
G4V46_04605	COG2706	6-phosphogluconolactonase activity
G4V46_04610	COG0628	permease
G4V46_04620	COG1674	ftsk spoiiie
G4V46_04630	COG4152	abc transporter atp-binding protein
G4V46_04635	COG1668	transmembrane transport
G4V46_04645	COG0322	excinuclease ABC activity
G4V46_04655	COG1739	Uncharacterized protein family UPF0029
G4V46_04665	COG2814	Major facilitator Superfamily
G4V46_04670	COG0516	GMP reductase activity
G4V46_04670	COG0517	IMP dehydrogenase activity
G4V46_04675	COG0516	GMP reductase activity
G4V46_04675	COG0517	IMP dehydrogenase activity
G4V46_04680	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G4V46_04685	COG0632	four-way junction helicase activity
G4V46_04690	COG2255	four-way junction helicase activity
G4V46_04695	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G4V46_04730	COG0343	queuine tRNA-ribosyltransferase activity
G4V46_04735	COG1862	Preprotein translocase
G4V46_04740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G4V46_04745	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G4V46_04750	COG0513	Belongs to the DEAD box helicase family
G4V46_04765	COG1929	Belongs to the glycerate kinase type-1 family
G4V46_04770	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G4V46_04785	COG3906	Belongs to the UPF0473 family
G4V46_04790	COG3906	Belongs to the UPF0473 family
G4V46_04795	COG1596	polysaccharide export
G4V46_04795	COG1555	photosystem II stabilization
G4V46_04800	COG2333	competence protein COMEC
G4V46_04800	COG0658	competence protein
G4V46_04805	COG1466	dna polymerase III delta subunit
G4V46_04810	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G4V46_04815	COG0268	Binds directly to 16S ribosomal RNA
G4V46_04850	COG0544	peptidyl-prolyl cis-trans isomerase activity
G4V46_04855	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G4V46_04860	COG0218	Necessary for normal cell division and for the maintenance of normal septation
G4V46_04885	COG1193	negative regulation of DNA recombination
G4V46_04910	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
G4V46_04925	COG3118	belongs to the thioredoxin family
G4V46_04930	COG0110	maltose O-acetyltransferase activity
G4V46_04935	COG0737	Belongs to the 5'-nucleotidase family
G4V46_04940	COG3842	ATPase activity
G4V46_04945	COG1175	transmembrane transport
G4V46_04950	COG0395	ABC-type sugar transport system, permease component
G4V46_04980	COG2801	Transposase and inactivated derivatives
G4V46_04995	COG0308	aminopeptidase N
G4V46_05030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G4V46_05050	COG0681	Belongs to the peptidase S26 family
G4V46_05070	COG1621	beta-fructofuranosidase activity
G4V46_05075	COG1609	Transcriptional regulator
G4V46_05110	COG1131	(ABC) transporter
G4V46_05125	COG4720	Psort location CytoplasmicMembrane, score
G4V46_05130	COG1122	ATPase activity
G4V46_05145	COG2801	Transposase and inactivated derivatives
G4V46_05200	COG2723	6-phospho-beta-galactosidase activity
G4V46_05225	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
G4V46_05230	COG0351	phosphomethylpyrimidine kinase
G4V46_05235	COG0352	thiamine-phosphate diphosphorylase activity
G4V46_05310	COG0546	phosphoglycolate phosphatase activity
G4V46_05315	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G4V46_05320	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G4V46_05335	COG2357	RelA SpoT domain protein
G4V46_05340	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G4V46_05345	COG0564	pseudouridine synthase activity
G4V46_05350	COG2239	Acts as a magnesium transporter
G4V46_05355	COG2814	Major facilitator Superfamily
G4V46_05360	COG1131	(ABC) transporter
G4V46_05385	COG1869	D-ribose catabolic process
G4V46_05390	COG0738	Major facilitator superfamily
G4V46_05430	COG2315	Protein conserved in bacteria
G4V46_05455	COG0446	pyridine nucleotide-disulphide oxidoreductase
G4V46_05480	COG0656	L-ascorbic acid biosynthetic process
G4V46_05485	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G4V46_05500	COG1846	Transcriptional regulator
G4V46_05505	COG0456	acetyltransferase
G4V46_05515	COG1309	transcriptional regulator
G4V46_05560	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G4V46_05570	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G4V46_05575	COG0738	Major facilitator superfamily
G4V46_05580	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G4V46_05585	COG0277	FAD linked oxidase domain protein
G4V46_05600	COG2814	Major facilitator Superfamily
G4V46_05605	COG1304	FMN binding
G4V46_05615	COG0779	Required for maturation of 30S ribosomal subunits
G4V46_05620	COG0195	Participates in both transcription termination and antitermination
G4V46_05625	COG2740	Nucleic-acid-binding protein implicated in transcription termination
G4V46_05635	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G4V46_05640	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G4V46_05645	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G4V46_05665	COG0196	riboflavin kinase activity
G4V46_05670	COG1293	RNA-binding protein homologous to eukaryotic snRNP
G4V46_05675	COG3142	Participates in the control of copper homeostasis
G4V46_05690	COG2270	Major facilitator Superfamily
G4V46_05695	COG1307	EDD domain protein, DegV family
G4V46_05700	COG1307	EDD domain protein, DegV family
G4V46_05705	COG2755	lipolytic protein G-D-S-L family
G4V46_05715	COG4479	Belongs to the UPF0346 family
G4V46_05725	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G4V46_05735	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G4V46_05740	COG4974	Belongs to the 'phage' integrase family
G4V46_05750	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G4V46_05755	COG0187	DNA topoisomerase II activity
G4V46_05775	COG3448	diguanylate cyclase activity
G4V46_05775	COG4175	Glycine betaine
G4V46_05785	COG0446	pyridine nucleotide-disulphide oxidoreductase
G4V46_05790	COG1464	Belongs to the NlpA lipoprotein family
G4V46_05795	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G4V46_05800	COG1597	lipid kinase activity
G4V46_05805	COG1011	Hydrolase
G4V46_05845	COG0242	peptide deformylase activity
G4V46_05850	COG4476	Belongs to the UPF0223 family
G4V46_05855	COG0483	inositol monophosphate 1-phosphatase activity
G4V46_05865	COG0772	Belongs to the SEDS family
G4V46_05870	COG4471	UPF0298 protein
G4V46_05875	COG0742	ribosomal rna small subunit methyltransferase
G4V46_05880	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G4V46_05885	COG3480	Lon protease (S16) C-terminal proteolytic domain
G4V46_05890	COG0105	UTP biosynthetic process
G4V46_05895	COG0477	Major facilitator Superfamily
G4V46_05900	COG0358	DNA primase activity
G4V46_05905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G4V46_05930	COG0745	RESPONSE REGULATOR receiver
G4V46_05935	COG5002	protein histidine kinase activity
G4V46_05940	COG0572	uridine kinase
G4V46_05945	COG1363	Peptidase, m42
G4V46_05950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G4V46_05960	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G4V46_05970	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G4V46_05970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G4V46_05975	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G4V46_05990	COG1484	DNA-dependent DNA replication
G4V46_06005	COG0745	RESPONSE REGULATOR receiver
G4V46_06010	COG5002	protein histidine kinase activity
G4V46_06030	COG1942	4-Oxalocrotonate Tautomerase
G4V46_06045	COG0706	membrane insertase activity
G4V46_06050	COG1028	Short-chain dehydrogenase reductase Sdr
G4V46_06055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4V46_06065	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G4V46_06080	COG0577	efflux transmembrane transporter activity
G4V46_06085	COG1136	(ABC) transporter
G4V46_06090	COG2076	Multidrug Resistance protein
G4V46_06095	COG2076	Multidrug Resistance protein
G4V46_06105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G4V46_06120	COG0281	malic enzyme
G4V46_06125	COG0583	DNA-binding transcription factor activity
G4V46_06130	COG4221	oxidoreductase activity
G4V46_06135	COG0531	amino acid
G4V46_06145	COG4708	membrane
G4V46_06165	COG0481	GTPase activity
G4V46_06175	COG0531	amino acid
G4V46_06205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4V46_06215	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G4V46_06230	COG1914	H( )-stimulated, divalent metal cation uptake system
G4V46_06260	COG2801	Transposase and inactivated derivatives
G4V46_06365	COG1719	4-vinyl reductase, 4VR
G4V46_06370	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G4V46_06380	COG1131	(ABC) transporter
G4V46_06385	COG0537	adenosine 5'-monophosphoramidase activity
G4V46_06395	COG0363	glucosamine-6-phosphate deaminase activity
G4V46_06400	COG3104	oligopeptide transport
G4V46_06420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4V46_06435	COG0825	malonyl-CoA metabolic process
G4V46_06440	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G4V46_06445	COG0439	Biotin carboxylase
G4V46_06455	COG0556	nucleotide-excision repair
G4V46_06470	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G4V46_06480	COG0116	Belongs to the methyltransferase superfamily
G4V46_06490	COG3599	regulation of cell shape
G4V46_06495	COG4474	Belongs to the UPF0398 family
G4V46_06500	COG3331	DNA recombination
G4V46_06505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G4V46_06510	COG1132	(ABC) transporter
G4V46_06515	COG1132	(ABC) transporter
G4V46_06520	COG0747	negative chemotaxis
G4V46_06525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4V46_06530	COG0601	transmembrane transport
G4V46_06535	COG4608	Belongs to the ABC transporter superfamily
G4V46_06540	COG0444	Belongs to the ABC transporter superfamily
G4V46_06545	COG3935	DnaD domain protein
G4V46_06645	COG2801	Transposase and inactivated derivatives
G4V46_06785	COG1396	sequence-specific DNA binding
G4V46_06810	COG0582	viral genome integration into host DNA
G4V46_06815	COG0017	Asparaginyl-tRNA synthetase
G4V46_06820	COG5353	protein conserved in bacteria
G4V46_06825	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G4V46_06825	COG1199	ATP-dependent helicase activity
G4V46_06845	COG1304	FMN binding
G4V46_06860	COG3620	sequence-specific DNA binding
G4V46_06875	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
G4V46_06880	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G4V46_06885	COG2190	(PTS) system
G4V46_06885	COG2211	Major facilitator Superfamily
G4V46_06900	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G4V46_06905	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G4V46_06920	COG2801	Transposase and inactivated derivatives
G4V46_06935	COG2357	RelA SpoT domain protein
G4V46_06955	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G4V46_06965	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G4V46_06975	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G4V46_06980	COG2384	SAM-dependent methyltransferase
G4V46_06985	COG0071	Belongs to the small heat shock protein (HSP20) family
G4V46_07020	COG0457	Tetratricopeptide repeat
G4V46_07055	COG0419	ATPase involved in DNA repair
G4V46_07060	COG0420	3'-5' exonuclease activity
G4V46_07070	COG2807	transmembrane transport
G4V46_07075	COG4720	Psort location CytoplasmicMembrane, score
G4V46_07090	COG1160	GTP binding
G4V46_07095	COG0539	negative regulation of cytoplasmic translation
G4V46_07100	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G4V46_07110	COG0514	ATP-dependent DNA helicase (RecQ)
G4V46_07120	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
G4V46_07135	COG1187	pseudouridine synthase activity
G4V46_07140	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G4V46_07145	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
G4V46_07160	COG2996	Protein conserved in bacteria
G4V46_07175	COG0475	glutathione-regulated potassium exporter activity
G4V46_07185	COG1490	D-aminoacyl-tRNA deacylase activity
G4V46_07190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G4V46_07195	COG0587	DNA-directed DNA polymerase activity
G4V46_07210	COG0488	(ABC) transporter
G4V46_07215	COG0617	tRNA 3'-terminal CCA addition
G4V46_07235	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G4V46_07240	COG0004	ammonium transporteR
G4V46_07255	COG4464	protein tyrosine phosphatase activity
G4V46_07260	COG1316	TRANSCRIPTIONal
G4V46_07270	COG0233	cytoplasmic translational termination
G4V46_07280	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G4V46_07300	COG2827	Endonuclease containing a URI domain
G4V46_07305	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
G4V46_07310	COG0204	Acyl-transferase
G4V46_07320	COG2801	Transposase and inactivated derivatives
G4V46_07330	COG3763	UPF0154 protein
G4V46_07335	COG4224	UPF0291 protein
G4V46_07340	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G4V46_07355	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G4V46_07355	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
G4V46_07360	COG1234	tRNA 3'-trailer cleavage
G4V46_07380	COG0484	heat shock protein binding
G4V46_07385	COG0443	Heat shock 70 kDa protein
G4V46_07395	COG1420	regulation of RNA biosynthetic process
G4V46_07405	COG1682	transport, permease protein
G4V46_07410	COG1388	LysM domain
G4V46_07410	COG1134	teichoic acid transport
G4V46_07420	COG1216	Glycosyl transferase, family 2
G4V46_07425	COG0562	UDP-galactopyranose mutase
G4V46_07435	COG0463	Glycosyl transferase, family 2
G4V46_07445	COG0024	Methionine aminopeptidase
G4V46_07470	COG2801	Transposase and inactivated derivatives
G4V46_07500	COG1705	Flagellar rod assembly protein muramidase FlgJ
G4V46_07500	COG1388	LysM domain
G4V46_07520	COG2235	arginine
G4V46_07540	COG2309	aminopeptidase activity
G4V46_07555	COG0564	pseudouridine synthase activity
G4V46_07560	COG1278	Cold shock
G4V46_07575	COG0741	lytic transglycosylase activity
G4V46_07585	COG3973	AAA domain
G4V46_07600	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G4V46_07605	COG1058	Belongs to the CinA family
G4V46_07605	COG1546	Belongs to the CinA family
G4V46_07610	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G4V46_07615	COG1426	Protein conserved in bacteria
G4V46_07620	COG0612	Peptidase, M16
G4V46_07625	COG0612	Peptidase, M16
G4V46_07645	COG1070	Carbohydrate kinase
G4V46_07675	COG0420	3'-5' exonuclease activity
G4V46_07680	COG3679	Belongs to the UPF0342 family
G4V46_07685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G4V46_07690	COG1438	arginine binding
G4V46_07695	COG0306	phosphate transporter
G4V46_07700	COG0519	Catalyzes the synthesis of GMP from XMP
G4V46_07705	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G4V46_07710	COG0018	arginyl-trna synthetase
G4V46_07725	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G4V46_07735	COG1121	(ABC) transporter
G4V46_07755	COG1597	lipid kinase activity
G4V46_07760	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G4V46_07765	COG0154	amidase activity
G4V46_07770	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G4V46_07775	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G4V46_07775	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
G4V46_07805	COG1914	H( )-stimulated, divalent metal cation uptake system
G4V46_07810	COG0456	acetyltransferase
G4V46_07830	COG0667	Aldo Keto reductase
G4V46_07835	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G4V46_07840	COG0167	dihydroorotate dehydrogenase activity
G4V46_07850	COG1122	ATPase activity
G4V46_07860	COG2115	Belongs to the xylose isomerase family
G4V46_07865	COG0710	3-dehydroquinate dehydratase activity
G4V46_07870	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G4V46_07875	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G4V46_07880	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G4V46_07885	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G4V46_07890	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
G4V46_07895	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G4V46_07915	COG0438	transferase activity, transferring glycosyl groups
G4V46_07930	COG4684	Psort location CytoplasmicMembrane, score
G4V46_07935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G4V46_07955	COG1609	Transcriptional regulator
G4V46_07960	COG0577	efflux transmembrane transporter activity
G4V46_07960	COG1136	(ABC) transporter
G4V46_07965	COG1136	(ABC) transporter
G4V46_07980	COG1131	(ABC) transporter
G4V46_07985	COG2188	Transcriptional regulator
G4V46_07995	COG0436	Aminotransferase
G4V46_08005	COG0596	Alpha beta hydrolase
G4V46_08010	COG4166	transmembrane transport
G4V46_08020	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G4V46_08025	COG0436	Aminotransferase
G4V46_08030	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G4V46_08035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G4V46_08040	COG1473	amidohydrolase
G4V46_08045	COG2171	N-acyltransferase activity
G4V46_08055	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G4V46_08060	COG0527	aspartate kinase activity
G4V46_08070	COG1609	Transcriptional regulator
G4V46_08075	COG0083	homoserine kinase activity
G4V46_08090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G4V46_08090	COG1321	iron dependent repressor
G4V46_08100	COG2801	Transposase and inactivated derivatives
G4V46_08105	COG3764	Sortase (surface protein transpeptidase)
G4V46_08110	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
G4V46_08115	COG0513	Belongs to the DEAD box helicase family
G4V46_08120	COG0673	inositol 2-dehydrogenase activity
G4V46_08125	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G4V46_08130	COG0501	Belongs to the peptidase M48B family
G4V46_08135	COG1704	LemA family
G4V46_08140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G4V46_08145	COG4115	mRNA cleavage
G4V46_08150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G4V46_08165	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G4V46_08170	COG0439	Biotin carboxylase
G4V46_08185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G4V46_08190	COG1028	Short-chain dehydrogenase reductase Sdr
G4V46_08195	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G4V46_08200	COG2070	2-Nitropropane dioxygenase
G4V46_08205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4V46_08210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G4V46_08215	COG1846	Transcriptional regulator
G4V46_08220	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G4V46_08230	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G4V46_08235	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G4V46_08245	COG0505	Belongs to the CarA family
G4V46_08255	COG0564	pseudouridine synthase activity
G4V46_08265	COG0328	RNA-DNA hybrid ribonuclease activity
G4V46_08305	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
G4V46_08310	COG1113	amino acid transport
G4V46_08325	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
G4V46_08345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G4V46_08350	COG1132	(ABC) transporter
G4V46_08355	COG1132	(ABC) transporter
G4V46_08360	COG0583	DNA-binding transcription factor activity
G4V46_08365	COG1811	Na channel or pump
G4V46_08370	COG0126	phosphoglycerate kinase activity
G4V46_08430	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
G4V46_08440	COG1696	Membrane protein involved in D-alanine export
G4V46_08455	COG0588	phosphoglycerate mutase activity
G4V46_08465	COG3716	PTS system mannose fructose sorbose family IID component
G4V46_08470	COG3715	PTS system
G4V46_08480	COG1027	Aspartate ammonia-lyase
G4V46_08490	COG1397	ADP-ribosylglycohydrolase
G4V46_08550	COG1368	sulfuric ester hydrolase activity
G4V46_08565	COG0438	transferase activity, transferring glycosyl groups
G4V46_08570	COG0438	transferase activity, transferring glycosyl groups
G4V46_08575	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G4V46_08580	COG0284	orotidine-5'-phosphate decarboxylase activity
G4V46_08585	COG0167	dihydroorotate dehydrogenase activity
G4V46_08590	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G4V46_08595	COG0505	Belongs to the CarA family
G4V46_08605	COG0540	Belongs to the ATCase OTCase family
G4V46_08630	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G4V46_08635	COG4856	YbbR-like protein
G4V46_08650	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G4V46_08660	COG0456	acetyltransferase
G4V46_08665	COG0802	atpase or kinase
G4V46_08670	COG0280	phosphate acetyltransferase
G4V46_08685	COG2076	Multidrug Resistance protein
G4V46_08690	COG2076	Multidrug Resistance protein
G4V46_08695	COG1126	abc transporter atp-binding protein
G4V46_08700	COG0765	amino acid transport
G4V46_08710	COG0557	exoribonuclease II activity
G4V46_08720	COG2814	Major facilitator Superfamily
G4V46_08730	COG2801	Transposase and inactivated derivatives
G4V46_08755	COG0149	triose-phosphate isomerase activity
G4V46_08760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G4V46_08765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G4V46_08775	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G4V46_08780	COG0492	ferredoxin-NADP+ reductase activity
G4V46_08795	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G4V46_08800	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G4V46_08805	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
G4V46_08820	COG0589	response to stress
G4V46_08830	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G4V46_08840	COG1177	transmembrane transport
G4V46_08850	COG3842	ATPase activity
G4V46_08860	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G4V46_08865	COG0049	tRNA binding
G4V46_08870	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G4V46_08885	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G4V46_08890	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G4V46_08895	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G4V46_08905	COG1302	Protein conserved in bacteria
G4V46_08910	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G4V46_08920	COG2017	converts alpha-aldose to the beta-anomer
G4V46_08930	COG4975	Glucose uptake
G4V46_08935	COG3850	Histidine kinase
G4V46_08935	COG5002	protein histidine kinase activity
G4V46_08940	COG0745	RESPONSE REGULATOR receiver
G4V46_08945	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G4V46_08950	COG0402	S-adenosylhomocysteine deaminase activity
G4V46_08965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G4V46_08980	COG0668	transmembrane transport
G4V46_08985	COG0516	GMP reductase activity
G4V46_08990	COG0446	pyridine nucleotide-disulphide oxidoreductase
G4V46_09070	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G4V46_09075	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G4V46_09075	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G4V46_09085	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G4V46_09085	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G4V46_09105	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G4V46_09130	COG2801	Transposase and inactivated derivatives
G4V46_09150	COG2801	Transposase and inactivated derivatives
G4V46_09165	COG1266	CAAX protease self-immunity
G4V46_09180	COG4166	transmembrane transport
G4V46_09200	COG0561	phosphatase activity
G4V46_09235	COG0577	efflux transmembrane transporter activity
G4V46_09240	COG1136	(ABC) transporter
G4V46_09250	COG0436	Aminotransferase
G4V46_09255	COG3759	membrane
G4V46_09260	COG2723	6-phospho-beta-galactosidase activity
G4V46_09265	COG1263	PTS System
G4V46_09265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4V46_09280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G4V46_09295	COG1609	Transcriptional regulator
G4V46_09325	COG2814	Major facilitator Superfamily
G4V46_09330	COG2217	Heavy metal translocating P-type atpase
G4V46_09340	COG0431	NADPH-dependent FMN reductase
G4V46_09355	COG2409	Drug exporters of the RND superfamily
G4V46_09355	COG1033	growth of symbiont in host cell
G4V46_09370	COG2183	response to ionizing radiation
G4V46_09380	COG2873	o-acetylhomoserine
G4V46_09385	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G4V46_09395	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
G4V46_09440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G4V46_09460	COG1131	(ABC) transporter
G4V46_09510	COG2176	DNA-directed DNA polymerase activity
G4V46_09515	COG0442	prolyl-tRNA aminoacylation
G4V46_09520	COG0750	zinc metalloprotease
G4V46_09525	COG4589	Belongs to the CDS family
G4V46_09530	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G4V46_09535	COG0561	phosphatase activity
G4V46_09585	COG0656	L-ascorbic acid biosynthetic process
G4V46_09595	COG2814	Major facilitator Superfamily
G4V46_09615	COG1307	EDD domain protein, DegV family
G4V46_09645	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G4V46_09655	COG2252	PERMEase
G4V46_09660	COG0352	thiamine-phosphate diphosphorylase activity
G4V46_09670	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
G4V46_09695	COG2801	Transposase and inactivated derivatives
G4V46_09705	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G4V46_09715	COG2188	Transcriptional regulator
G4V46_09725	COG1250	3-hydroxyacyl-CoA dehydrogenase
G4V46_09730	COG1136	(ABC) transporter
G4V46_09730	COG0577	efflux transmembrane transporter activity
G4V46_09740	COG0561	phosphatase activity
G4V46_09745	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G4V46_09750	COG0561	phosphatase activity
G4V46_09765	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G4V46_09770	COG0772	Belongs to the SEDS family
G4V46_09780	COG1077	Cell shape determining protein MreB Mrl
G4V46_09785	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G4V46_09810	COG1744	ABC transporter substrate-binding protein PnrA-like
G4V46_09815	COG1744	ABC transporter substrate-binding protein PnrA-like
G4V46_09820	COG1744	ABC transporter substrate-binding protein PnrA-like
G4V46_09825	COG0446	pyridine nucleotide-disulphide oxidoreductase
G4V46_09835	COG0640	Transcriptional regulator
G4V46_09840	COG0628	permease
G4V46_09845	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4V46_09860	COG0588	phosphoglycerate mutase activity
G4V46_09865	COG0492	ferredoxin-NADP+ reductase activity
G4V46_09885	COG1744	ABC transporter substrate-binding protein PnrA-like
G4V46_09895	COG2832	Protein of unknown function (DUF454)
G4V46_09930	COG2814	Major facilitator Superfamily
G4V46_09935	COG0305	Participates in initiation and elongation during chromosome replication
G4V46_09940	COG0359	binds to the 23S rRNA
G4V46_09950	COG4608	Belongs to the ABC transporter superfamily
G4V46_09955	COG0444	Belongs to the ABC transporter superfamily
G4V46_09960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4V46_09965	COG0601	transmembrane transport
G4V46_09970	COG4166	transmembrane transport
G4V46_09975	COG1957	nucleoside hydrolase
G4V46_09985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G4V46_10005	COG2801	Transposase and inactivated derivatives
G4V46_10035	COG1609	Transcriptional regulator
G4V46_10045	COG2814	Major facilitator Superfamily
G4V46_10055	COG0765	amino acid transport
G4V46_10060	COG0765	amino acid transport
G4V46_10065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4V46_10070	COG1126	abc transporter atp-binding protein
G4V46_10085	COG0194	GDP metabolic process
G4V46_10090	COG1268	BioY protein
G4V46_10120	COG2211	Major facilitator Superfamily
G4V46_10125	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G4V46_10130	COG0673	inositol 2-dehydrogenase activity
G4V46_10145	COG3973	AAA domain
G4V46_10155	COG2337	Toxic component of a toxin-antitoxin (TA) module
G4V46_10160	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G4V46_10170	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G4V46_10175	COG0504	CTP synthase activity
G4V46_10195	COG3343	RNA polymerase activity
G4V46_10200	COG0561	phosphatase activity
G4V46_10205	COG1078	dGTPase activity
G4V46_10215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G4V46_10220	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
G4V46_10235	COG5002	protein histidine kinase activity
G4V46_10240	COG0745	RESPONSE REGULATOR receiver
G4V46_10270	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G4V46_10275	COG0629	single-stranded DNA binding
G4V46_10280	COG0360	Binds together with S18 to 16S ribosomal RNA
G4V46_10290	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G4V46_10300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G4V46_10305	COG1051	belongs to the nudix hydrolase family
G4V46_10315	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G4V46_10320	COG2814	Major facilitator Superfamily
G4V46_10325	COG1064	alcohol dehydrogenase
G4V46_10330	COG1074	ATP-dependent DNA helicase activity
G4V46_10335	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
G4V46_10340	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G4V46_10345	COG0531	amino acid
G4V46_10350	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G4V46_10360	COG1902	pentaerythritol trinitrate reductase activity
G4V46_10365	COG0626	cystathionine gamma-synthase activity
G4V46_10375	COG2244	polysaccharide biosynthetic process
G4V46_10385	COG0438	transferase activity, transferring glycosyl groups
G4V46_10390	COG0495	leucyl-tRNA aminoacylation
G4V46_10395	COG0671	phosphoesterase, PA-phosphatase related
G4V46_10405	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G4V46_10425	COG1744	ABC transporter substrate-binding protein PnrA-like
G4V46_10470	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
G4V46_10500	COG2801	Transposase and inactivated derivatives
G4V46_10510	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G4V46_10520	COG0024	Methionine aminopeptidase
G4V46_10530	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G4V46_10535	COG0737	Belongs to the 5'-nucleotidase family
G4V46_10540	COG3639	organic phosphonate transmembrane transporter activity
G4V46_10550	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
G4V46_10570	COG0604	alcohol dehydrogenase
G4V46_10575	COG1435	thymidine kinase activity
G4V46_10580	COG1316	TRANSCRIPTIONal
G4V46_10590	COG2205	protein histidine kinase activity
G4V46_10595	COG0745	RESPONSE REGULATOR receiver
G4V46_10615	COG1914	H( )-stimulated, divalent metal cation uptake system
G4V46_10680	COG0438	transferase activity, transferring glycosyl groups
G4V46_10685	COG2084	Dehydrogenase
G4V46_10700	COG4989	oxidoreductase activity
G4V46_10705	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G4V46_10710	COG2233	PERMEase
G4V46_10725	COG1956	GAF domain-containing protein
G4V46_10735	COG1216	Glycosyl transferase, family 2
G4V46_10750	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G4V46_10775	COG0531	amino acid
G4V46_10780	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G4V46_10785	COG2235	arginine
G4V46_10790	COG2910	NAD(P)H-binding
G4V46_10810	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
G4V46_10815	COG1737	Transcriptional regulator
G4V46_10825	COG0656	L-ascorbic acid biosynthetic process
G4V46_10830	COG2261	transglycosylase associated protein
G4V46_10895	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G4V46_10900	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G4V46_10925	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
G4V46_10930	COG2244	polysaccharide biosynthetic process
G4V46_10935	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G4V46_10940	COG0193	aminoacyl-tRNA hydrolase activity
G4V46_10950	COG3103	Sh3 type 3 domain protein
G4V46_10950	COG0366	Alpha amylase catalytic
G4V46_10955	COG0058	SHG alpha-glucan phosphorylase activity
G4V46_10965	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G4V46_10975	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G4V46_10980	COG1511	domain protein
G4V46_10985	COG1309	transcriptional regulator
G4V46_11005	COG0477	Major facilitator Superfamily
G4V46_11020	COG2115	Belongs to the xylose isomerase family
G4V46_11025	COG1940	carbohydrate kinase activity
G4V46_11025	COG1846	Transcriptional regulator
G4V46_11030	COG2211	Major facilitator Superfamily
G4V46_11035	COG3507	Belongs to the glycosyl hydrolase 43 family
G4V46_11060	COG1968	undecaprenyl-diphosphatase activity
G4V46_11075	COG1695	Transcriptional regulator
G4V46_11080	COG1983	PspC domain protein
G4V46_11085	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G4V46_11090	COG1316	TRANSCRIPTIONal
G4V46_11100	COG2131	deaminase
G4V46_11105	COG4466	Protein conserved in bacteria
G4V46_11110	COG1253	flavin adenine dinucleotide binding
G4V46_11115	COG1253	flavin adenine dinucleotide binding
G4V46_11120	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G4V46_11125	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
G4V46_11130	COG0084	hydrolase, TatD family'
G4V46_11140	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G4V46_11140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G4V46_11170	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G4V46_11190	COG1368	sulfuric ester hydrolase activity
G4V46_11210	COG0187	DNA topoisomerase II activity
G4V46_11215	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G4V46_11220	COG2501	S4 domain
G4V46_11225	COG0592	DNA-directed DNA polymerase activity
G4V46_11360	COG1396	sequence-specific DNA binding
G4V46_11385	COG2801	Transposase and inactivated derivatives
G4V46_11390	COG1573	uracil-dna glycosylase
G4V46_11435	COG2217	Heavy metal translocating P-type atpase
G4V46_11440	COG2217	Heavy metal translocating P-type atpase
G4V46_11445	COG3682	Transcriptional regulator
G4V46_11450	COG1573	uracil-dna glycosylase
G4V46_11485	COG0783	Belongs to the Dps family
G4V46_11490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein