locus-tag	class	description
C6P08_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
C6P08_00010	ENOG4105VG0	50S ribosomal protein l34
C6P08_00015	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
C6P08_00020	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
C6P08_00025	ENOG4105C3F	Signal peptidase i
C6P08_00030	ENOG4105E0A	ABC, transporter
C6P08_00035	ENOG4105EHG	Permease protein
C6P08_00055	ENOG4107ZYR	domain protein
C6P08_00060	ENOG4105C85	amino acid
C6P08_00100	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
C6P08_00110	ENOG4108HCJ	Hydrolase
C6P08_00120	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C6P08_00145	ENOG4105C7N	Xanthine uracil vitamin C permease
C6P08_00150	ENOG4108YYH	Nadph-dependent fmn reductase
C6P08_00170	ENOG4105CP7	Triose-phosphate isomerase
C6P08_00190	ENOG4105KIS	phospholipid-binding protein
C6P08_00205	ENOG4108IJ8	ABC transporter
C6P08_00210	ENOG4105E90	ABC transporter
C6P08_00220	ENOG4105D01	(LipO)protein
C6P08_00225	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
C6P08_00245	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C6P08_00250	ENOG4105DIH	basic membrane
C6P08_00255	ENOG4105CDH	Citrulline--aspartate ligase
C6P08_00260	ENOG4105CH7	arginosuccinase
C6P08_00265	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
C6P08_00270	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
C6P08_00275	ENOG4105CAS	nag kinase
C6P08_00280	ENOG4105C8Y	Acetylornithine aminotransferase
C6P08_00285	ENOG4105DBV	ornithine carbamoyltransferase
C6P08_00290	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
C6P08_00330	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C6P08_00335	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C6P08_00345	ENOG4108UZ3	Transporter
C6P08_00365	ENOG4105FS7	Transcriptional regulator
C6P08_00370	ENOG4105BZ1	(ABC) transporter
C6P08_00390	ENOG41083J0	(ABC) transporter
C6P08_00395	ENOG4105C4B	ABC transporter, permease
C6P08_00400	ENOG4105CDA	abc transporter atp-binding protein
C6P08_00405	ENOG4105E5Q	amino acid AbC transporter
C6P08_00415	ENOG4105EAB	amino acid AbC transporter
C6P08_00420	ENOG410855V	Acylphosphatase
C6P08_00445	ENOG4105KVH	Transcriptional regulator
C6P08_00460	ENOG4105D9M	gamma-glutamylcysteine synthetase
C6P08_00470	ENOG4105C85	amino acid
C6P08_00505	ENOG4105HMI	Membrane
C6P08_00525	ENOG4105CI2	imidazolone-5-propionate hydrolase
C6P08_00530	ENOG4105CUB	amino acid
C6P08_00540	ENOG4105CSC	Glucose uptake protein
C6P08_00545	ENOG4105EVU	fructokinase
C6P08_00555	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C6P08_00565	ENOG4107U9W	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX (By similarity)
C6P08_00575	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
C6P08_00580	ENOG4105CPQ	Dehydrogenase
C6P08_00585	ENOG4108W5N	phosphatidylglycerophosphatase a
C6P08_00590	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C6P08_00595	ENOG4105CSC	Glucose uptake protein
C6P08_00600	ENOG4107R7I	amino acid
C6P08_00635	ENOG4105CUB	amino acid
C6P08_00640	ENOG4105HDK	L-asparaginase
C6P08_00645	ENOG4105VEM	Conserved domain protein
C6P08_00655	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C6P08_00665	ENOG4105KA0	thioesterase Superfamily protein
C6P08_00670	ENOG4108IPT	Naphthoate synthase
C6P08_00675	ENOG4105CEY	Amp-dependent synthetase and ligase
C6P08_00690	ENOG4105DU1	integral membrane protein, terc
C6P08_00695	ENOG4108STX	response regulator
C6P08_00700	ENOG4105US7	Histidine kinase
C6P08_00705	ENOG4105EK5	Glycoside hydrolase family 8
C6P08_00720	ENOG41075H3	AraC family transcriptional regulator
C6P08_00735	ENOG4105E66	phosphoriboisomerase A
C6P08_00740	ENOG4105CEN	a g-specific adenine glycosylase
C6P08_00745	ENOG4105DU0	nucleoside hydrolase
C6P08_00755	ENOG4107QJE	Chromosome Partitioning Protein
C6P08_00760	ENOG4105FA0	parb-like partition protein
C6P08_00765	ENOG4105VDK	protein, conserved in bacteria
C6P08_00770	ENOG4105C3G	gtp-binding protein
C6P08_00780	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C6P08_00845	ENOG4105DUX	Transporter
C6P08_00885	ENOG410906U	SprT-like
C6P08_00890	ENOG4107QW4	alcohol dehydrogenase
C6P08_00895	ENOG4105EXC	Acyl-transferase
C6P08_00900	ENOG4107DA6	Transcriptional regulator
C6P08_00910	ENOG4105FDK	ABC transporter
C6P08_00920	ENOG4105C5H	ABC transporter
C6P08_00925	ENOG4107R73	Mate efflux family protein
C6P08_00950	ENOG4107QNK	)-transporter
C6P08_00960	ENOG4105E5Q	amino acid AbC transporter
C6P08_00980	ENOG4107QNK	)-transporter
C6P08_01000	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C6P08_01005	ENOG4108TZY	GntR Family Transcriptional Regulator
C6P08_01010	ENOG4107QRI	Phosphoketolase
C6P08_01065	ENOG4105C9K	Endothelin-converting enzyme 1
C6P08_01075	ENOG4105C5Y	PTS System
C6P08_01080	ENOG4105C5Y	PTS System
C6P08_01085	ENOG4105CG3	alpha amylase, catalytic region
C6P08_01090	ENOG4108EKI	Dehydrogenase
C6P08_01100	ENOG4105CGK	Exodeoxyribonuclease III
C6P08_01105	ENOG4105DA5	(ABC) transporter
C6P08_01125	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C6P08_01130	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
C6P08_01140	ENOG4105BZ1	(ABC) transporter
C6P08_01145	ENOG4105BZ1	(ABC) transporter
C6P08_01175	ENOG4105DG6	mannose-6-phosphate isomerase
C6P08_01185	ENOG4105DMS	mur ligase
C6P08_01190	ENOG4105F1K	Glutamine amidotransferase
C6P08_01210	ENOG4107104	thymidine kinase
C6P08_01220	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C6P08_01225	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C6P08_01230	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
C6P08_01235	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
C6P08_01240	ENOG4105CGD	Nad-dependent epimerase dehydratase
C6P08_01250	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
C6P08_01255	ENOG4105WS6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C6P08_01260	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
C6P08_01265	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C6P08_01270	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
C6P08_01275	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
C6P08_01280	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
C6P08_01285	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
C6P08_01290	ENOG4108VXD	carboxy-peptidase
C6P08_01295	ENOG4105ZMH	deoxynucleoside kinase
C6P08_01300	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
C6P08_01335	ENOG4105KEX	transcriptional regulator, ctsr
C6P08_01340	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C6P08_01345	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C6P08_01350	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C6P08_01355	ENOG4107QW4	alcohol dehydrogenase
C6P08_01365	ENOG4105DHI	Methyltransferase
C6P08_01385	ENOG4105E4P	ATPase (AAA
C6P08_01405	ENOG4105DJ2	Major Facilitator Superfamily
C6P08_01410	ENOG4108URH	decarboxylase
C6P08_01415	ENOG4107Y49	methyltransferase
C6P08_01430	ENOG4105C6E	dna polymerase iii
C6P08_01440	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
C6P08_01455	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
C6P08_01460	ENOG4105X0R	protein from nitrogen regulatory protein P-II
C6P08_01480	ENOG4105CMR	udp-glucose 4-epimerase
C6P08_01485	ENOG41072GX	Peptidase M22 Glycoprotease
C6P08_01510	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
C6P08_01515	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
C6P08_01520	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
C6P08_01525	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
C6P08_01530	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C6P08_01540	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
C6P08_01545	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
C6P08_01555	ENOG41082SA	50s ribosomal protein l29
C6P08_01560	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
C6P08_01565	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
C6P08_01570	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
C6P08_01575	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C6P08_01580	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
C6P08_01585	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
C6P08_01590	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
C6P08_01595	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
C6P08_01605	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
C6P08_01610	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
C6P08_01620	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
C6P08_01625	ENOG41067V7	50S ribosomal protein L36
C6P08_01630	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C6P08_01635	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
C6P08_01640	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C6P08_01645	ENOG4108ZT0	50S ribosomal protein l17
C6P08_01670	ENOG4108UMI	ABC transporter, permease
C6P08_01675	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
C6P08_01680	ENOG4105D01	(LipO)protein
C6P08_01690	ENOG4105DAP	Nicotinate phosphoribosyltransferase
C6P08_01695	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
C6P08_01700	ENOG4107VC8	ATP cone domain protein
C6P08_01715	ENOG4105C8N	cysteinyl-tRNA synthetase
C6P08_01720	ENOG4105CHR	reductase
C6P08_01735	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
C6P08_01740	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C6P08_01745	ENOG4105C2N	RNA methyltransferase TrmH family group 3
C6P08_01755	ENOG4107FTN	50S ribosomal protein L33
C6P08_01760	ENOG410683Z	Preprotein translocase SecE subunit
C6P08_01765	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
C6P08_01770	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
C6P08_01775	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
C6P08_01780	ENOG4108VZM	50s ribosomal protein L10
C6P08_01785	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
C6P08_01795	ENOG4105DIK	(ABC) transporter
C6P08_01800	ENOG4105CC5	ABC transporter
C6P08_01805	ENOG4105DSE	periplasmic solute binding protein
C6P08_01820	ENOG4108JJB	ABC transporter
C6P08_01825	ENOG4108JJB	ABC transporter
C6P08_01835	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
C6P08_01840	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
C6P08_01845	ENOG4108UJD	30S ribosomal protein S9
C6P08_01855	ENOG4106ISY	Putative cell wall binding repeat
C6P08_01860	ENOG4105F27	Major Facilitator
C6P08_01870	ENOG4105C7K	acetolactate synthase
C6P08_01875	ENOG4108RG0	uracil-dna glycosylase
C6P08_01885	ENOG4105CG3	alpha amylase, catalytic region
C6P08_01895	ENOG410841Q	phosphoesterase PA-phosphatase related protein
C6P08_01905	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C6P08_01910	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C6P08_01935	ENOG4105CHW	UPF0052 protein
C6P08_01940	ENOG4105CIE	May be required for sporulation (By similarity)
C6P08_01960	ENOG4105C5Y	PTS System
C6P08_01965	ENOG41086FC	50S ribosomal protein l32
C6P08_01970	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
C6P08_01990	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
C6P08_02000	ENOG4107QJZ	Glycosyl transferase, family 2
C6P08_02015	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
C6P08_02025	ENOG4107FQX	Alpha-acetolactate decarboxylase
C6P08_02035	ENOG4105K4H	Nlp p60 protein
C6P08_02050	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
C6P08_02060	ENOG4105CTP	PilT protein domain protein
C6P08_02065	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
C6P08_02075	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
C6P08_02080	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
C6P08_02085	ENOG4105D2N	Aldolase
C6P08_02090	ENOG4105GP2	5'(3')-deoxyribonucleotidase
C6P08_02110	ENOG4108RWN	rrna methyltransferase
C6P08_02135	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
C6P08_02140	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
C6P08_02150	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C6P08_02155	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
C6P08_02165	ENOG4107RF6	penicillin-binding protein
C6P08_02170	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
C6P08_02175	ENOG4107ZXI	Rhomboid family
C6P08_02195	ENOG4108K5P	(LipO)protein
C6P08_02200	ENOG4107YZP	Rhodanese domain protein
C6P08_02220	ENOG4105KV4	Transcriptional regulator
C6P08_02225	ENOG4105C5F	glutamine synthetase
C6P08_02255	ENOG4105K46	50S ribosomal protein l27
C6P08_02355	ENOG4108UUM	single-stranded DNA-binding protein
C6P08_02535	ENOG4105BZ1	(ABC) transporter
C6P08_02540	ENOG4105E4F	Isochorismate synthase
C6P08_02545	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
C6P08_02550	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
C6P08_02555	ENOG4105DTQ	mandelate racemase muconate lactonizing
C6P08_02560	ENOG4105DC7	peptidase M24
C6P08_02575	ENOG4107R8B	5'-nucleotidase
C6P08_02580	ENOG4105MMD	transcriptional regulator
C6P08_02585	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
C6P08_02595	ENOG4105D9R	oxidoreductase
C6P08_02600	ENOG4105DU0	nucleoside hydrolase
C6P08_02615	ENOG4105CVA	phosphate
C6P08_02620	ENOG4105C8U	phosphate abc transporter
C6P08_02625	ENOG4105E2Z	phosphate ABC transporter (Permease
C6P08_02630	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
C6P08_02635	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
C6P08_02640	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
C6P08_02645	ENOG410902V	Modulates RecA activity (By similarity)
C6P08_02660	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
C6P08_02675	ENOG4105D1H	recombination factor protein RarA
C6P08_02685	ENOG4107YZX	Universal stress protein
C6P08_02705	ENOG4108UT2	hemolysin iii
C6P08_02720	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
C6P08_02725	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
C6P08_02740	ENOG4105C5H	ABC transporter
C6P08_02760	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
C6P08_02765	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
C6P08_02770	ENOG4105C0X	amino acid
C6P08_02785	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
C6P08_02790	ENOG4105CQW	ribosome biogenesis GTPase YqeH
C6P08_02800	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
C6P08_02805	ENOG4108WF2	Metal Dependent Phosphohydrolase
C6P08_02815	ENOG4105DXX	methyltransferase
C6P08_02820	ENOG4105CDE	UPF0348 protein
C6P08_02835	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
C6P08_02845	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
C6P08_02860	ENOG4105CEY	Amp-dependent synthetase and ligase
C6P08_02885	ENOG4105C22	threonyL-tRNA synthetase
C6P08_02890	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
C6P08_02895	ENOG4105K70	DNA-binding protein
C6P08_02905	ENOG4107WD8	ABC transporter, permease
C6P08_02925	ENOG4108V7D	UPF0397 protein
C6P08_02930	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
C6P08_02940	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C6P08_02945	ENOG4105CTB	Polyprenyl synthetase
C6P08_02950	ENOG4105DX0	Hemolysin A
C6P08_02955	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
C6P08_02960	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
C6P08_02970	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
C6P08_02975	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
C6P08_02990	ENOG4105DQR	SNARE associated Golgi
C6P08_02995	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
C6P08_03110	ENOG4108JQ1	Dehydrogenase
C6P08_03120	ENOG4105C4M	(Ubiquinol oxidase) subunit I
C6P08_03125	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
C6P08_03130	ENOG4108JJ9	ABC, transporter
C6P08_03135	ENOG4108JJ8	(ABC) transporter
C6P08_03140	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
C6P08_03145	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
C6P08_03175	ENOG4105VEQ	Cold shock protein
C6P08_03180	ENOG4108YZ4	nudix hydrolase
C6P08_03190	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
C6P08_03230	ENOG41067VN	Glutaredoxin
C6P08_03235	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C6P08_03250	ENOG4105C7J	ABC transporter, permease
C6P08_03255	ENOG4108JJB	ABC transporter
C6P08_03260	ENOG4105CMQ	Chloride channel
C6P08_03265	ENOG41087RV	Protein CrcB homolog
C6P08_03270	ENOG4106A8V	Protein CrcB homolog
C6P08_03275	ENOG4105EPR	degv family
C6P08_03280	ENOG4105CI1	PTS System
C6P08_03295	ENOG4105W5Q	DNA repair protein (RadC
C6P08_03300	ENOG4105DFF	Rod shape-determining protein mreb
C6P08_03305	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
C6P08_03320	ENOG4105E5Q	amino acid AbC transporter
C6P08_03325	ENOG4105CDA	abc transporter atp-binding protein
C6P08_03330	ENOG4105EAB	amino acid AbC transporter
C6P08_03340	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
C6P08_03345	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
C6P08_03365	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
C6P08_03380	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
C6P08_03385	ENOG4105DC1	bifunctional purine biosynthesis protein purh
C6P08_03390	ENOG4105C12	Phosphoribosylglycinamide synthetase
C6P08_03395	ENOG4105CKU	formyltetrahydrofolate synthetase
C6P08_03410	ENOG4108IQI	permease
C6P08_03415	ENOG4105CA9	Pyruvate kinase
C6P08_03420	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
C6P08_03425	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
C6P08_03440	ENOG4108V6E	Cell division protein mraZ
C6P08_03455	ENOG4105CJN	penicillin-binding protein
C6P08_03460	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
C6P08_03465	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
C6P08_03470	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
C6P08_03475	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
C6P08_03480	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
C6P08_03485	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
C6P08_03490	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
C6P08_03515	ENOG4107TB6	phosphoglycerate mutase
C6P08_03525	ENOG4105C7H	Helicase, RecD TraA family
C6P08_03530	ENOG4105CDY	transcriptional regulatory protein
C6P08_03535	ENOG4105C7N	Xanthine uracil vitamin C permease
C6P08_03580	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
C6P08_03630	ENOG4105C25	Primosomal protein n'
C6P08_03635	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
C6P08_03640	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
C6P08_03650	ENOG4105D9P	serine threonine protein kinase
C6P08_03655	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
C6P08_03660	ENOG4105DJV	ribulose-phosphate 3-epimerase
C6P08_03665	ENOG4105FJ0	thiamine
C6P08_03670	ENOG4105VB9	50S ribosomal protein l28
C6P08_03680	ENOG4105DP4	dak2 domain fusion protein ylov
C6P08_03690	ENOG4105CB5	ATP-dependent DNA helicase recG
C6P08_03695	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
C6P08_03700	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C6P08_03705	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
C6P08_03710	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
C6P08_03715	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
C6P08_03725	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C6P08_03750	ENOG4105K5M	30s ribosomal protein S16
C6P08_03765	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C6P08_03770	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
C6P08_03775	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
C6P08_03780	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
C6P08_03790	ENOG4107AYK	membrAne
C6P08_03795	ENOG41069HH	4-oxalocrotonate tautomerase
C6P08_03810	ENOG4105ZMH	deoxynucleoside kinase
C6P08_03815	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
C6P08_03820	ENOG410667J	hydrolase
C6P08_03855	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C6P08_04175	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
C6P08_04185	ENOG4105CDW	Resistance protein
C6P08_04190	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
C6P08_04195	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
C6P08_04200	ENOG4105CS2	ec 3.2.1.21
C6P08_04205	ENOG4105VZJ	PTS System
C6P08_04210	ENOG4105VCP	PTS System
C6P08_04215	ENOG4105CS2	ec 3.2.1.21
C6P08_04220	ENOG4105CK1	PTS System
C6P08_04230	ENOG4105DPN	Oligoendopeptidase f
C6P08_04235	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
C6P08_04250	ENOG4105ETE	Transcriptional regulator (LacI family
C6P08_04255	ENOG4105DC7	peptidase M24
C6P08_04330	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
C6P08_04335	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
C6P08_04360	ENOG4105CUT	histidyl-tRNA synthetase
C6P08_04365	ENOG4105C9M	aspartyl-trna synthetase
C6P08_04370	ENOG4107AYK	membrAne
C6P08_04375	ENOG4105VCC	30S ribosomal protein S21
C6P08_04380	ENOG4105KTH	gatB Yqey
C6P08_04385	ENOG4105C9A	Phoh family
C6P08_04390	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
C6P08_04400	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
C6P08_04425	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
C6P08_04430	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
C6P08_04435	ENOG4105DU1	integral membrane protein, terc
C6P08_04445	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
C6P08_04455	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
C6P08_04460	ENOG4105CNU	cell division protein FtsK
C6P08_04470	ENOG4108IUX	(ABC) transporter
C6P08_04475	ENOG4105RHA	ABC transporter, permease
C6P08_04490	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
C6P08_04495	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C6P08_04500	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
C6P08_04515	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C6P08_04520	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C6P08_04525	ENOG4105CPN	adenine deaminase
C6P08_04530	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
C6P08_04535	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
C6P08_04540	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
C6P08_04580	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
C6P08_04585	ENOG4105VIE	preprotein translocase, subunit YajC
C6P08_04590	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C6P08_04595	ENOG4105SFS	phosphoesterase RecJ domain protein
C6P08_04600	ENOG4105C1J	atp-dependent rna helicase
C6P08_04605	ENOG4108MCI	Transcriptional regulator, ARAC family
C6P08_04610	ENOG4108SUT	Major Facilitator Superfamily
C6P08_04625	ENOG4105BZW	Glycerate kinase
C6P08_04630	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
C6P08_04635	ENOG4105VBH	UPF0297 protein
C6P08_04640	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
C6P08_04645	ENOG4105VPH	UPF0473 protein
C6P08_04650	ENOG4105VPH	UPF0473 protein
C6P08_04655	ENOG4105KQC	Competence protein
C6P08_04660	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
C6P08_04665	ENOG4105TQK	DNA polymerase iii, delta' subunit
C6P08_04670	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
C6P08_04675	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
C6P08_04695	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
C6P08_04710	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
C6P08_04715	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
C6P08_04720	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
C6P08_04740	ENOG4105C98	muts2 protein
C6P08_04755	ENOG4107R8N	Glycosyl transferase, family 2
C6P08_04765	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
C6P08_04775	ENOG4105K63	Thioredoxin
C6P08_04780	ENOG4108UW5	maltose o-acetyltransferase
C6P08_04785	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
C6P08_04790	ENOG4108IJ9	(ABC) transporter
C6P08_04795	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
C6P08_04800	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
C6P08_04815	ENOG4105CD8	aminopeptidase N
C6P08_04845	ENOG4105C7H	Helicase, RecD TraA family
C6P08_04855	ENOG4105CH6	catalase
C6P08_04865	ENOG4105C3F	Signal peptidase i
C6P08_04875	ENOG4105C5Y	PTS System
C6P08_04920	ENOG4105CPQ	Dehydrogenase
C6P08_04930	ENOG4108V7D	UPF0397 protein
C6P08_04935	ENOG4108JJB	ABC transporter
C6P08_04945	ENOG4108J59	Extracellular solute-binding protein, family 5
C6P08_04950	ENOG4105CI2	imidazolone-5-propionate hydrolase
C6P08_04970	ENOG4105D85	methylase
C6P08_05015	ENOG4105CS2	ec 3.2.1.21
C6P08_05050	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
C6P08_05055	ENOG4105DWF	phosphomethylpyrimidine kinase
C6P08_05060	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
C6P08_05135	ENOG4107XGZ	Hydrolase
C6P08_05140	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
C6P08_05145	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
C6P08_05165	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
C6P08_05170	ENOG4105EMS	pseudouridine synthase
C6P08_05175	ENOG4105CJW	magnesium transporter
C6P08_05180	ENOG4105C2C	drug resistance transporter, Bcr CflA
C6P08_05205	ENOG4105UNS	Pfam:DUF419
C6P08_05220	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
C6P08_05245	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
C6P08_05260	ENOG4108U05	Transcriptional regulator
C6P08_05315	ENOG4105CQB	FAD linked oxidase domain protein
C6P08_05320	ENOG4105CHM	Aminotransferase
C6P08_05330	ENOG4105D01	(LipO)protein
C6P08_05365	ENOG4108JSS	Haloalkane dehalogenase
C6P08_05370	ENOG41090U3	tautomerase
C6P08_05390	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
C6P08_05395	ENOG4105JAB	phenazine biosynthesis protein, phzf family
C6P08_05410	ENOG4105CPQ	Dehydrogenase
C6P08_05445	ENOG4105CQ4	Transcriptional regulator
C6P08_05450	ENOG4107RBJ	symporter
C6P08_05455	ENOG4105DME	alpha-galactosidase
C6P08_05485	ENOG4105GP2	5'(3')-deoxyribonucleotidase
C6P08_05490	ENOG4105E98	transcriptional regulator DeoR family
C6P08_05495	ENOG4105DE4	1-phosphofructokinase
C6P08_05500	ENOG4105DM4	PTS System
C6P08_05520	ENOG4105FCD	Major Facilitator
C6P08_05560	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
C6P08_05570	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
C6P08_05575	ENOG4105EMV	Major Facilitator
C6P08_05580	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
C6P08_05585	ENOG4105CXG	d-lactate dehydrogenase
C6P08_05605	ENOG4105CZM	Major Facilitator
C6P08_05625	ENOG4105CHV	Transcription elongation factor NusA
C6P08_05630	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
C6P08_05640	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
C6P08_05645	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
C6P08_05650	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
C6P08_05655	ENOG4105CEP	NADH dehydrogenase
C6P08_05665	ENOG4105DTN	riboflavin biosynthesis protein ribF
C6P08_05670	ENOG4105F23	Fibronectin-binding protein
C6P08_05675	ENOG4106N3A	copper homeostasis protein cutc
C6P08_05690	ENOG4105DEU	major facilitator superfamily
C6P08_05695	ENOG4105EPR	degv family
C6P08_05700	ENOG4108RCR	degv family
C6P08_05705	ENOG41090WU	lipolytic protein G-D-S-L family
C6P08_05715	ENOG4105VSD	UPF0346 protein
C6P08_05720	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
C6P08_05725	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C6P08_05730	ENOG4105C79	DNA protecting protein DprA
C6P08_05735	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
C6P08_05740	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C6P08_05750	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
C6P08_05755	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C6P08_05765	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
C6P08_05775	ENOG4108IJ7	Glycine betaine
C6P08_05785	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
C6P08_05790	ENOG4105D01	(LipO)protein
C6P08_05795	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
C6P08_05845	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C6P08_05850	ENOG4105WBI	UPF0223 protein
C6P08_05855	ENOG4105ECY	inositol monophosphatase
C6P08_05860	ENOG4105CI3	gtp-binding protein typa
C6P08_05865	ENOG4105CNI	cell division protein FtsW
C6P08_05870	ENOG4105WUC	UPF0298 protein
C6P08_05875	ENOG4106H78	methyltransferase
C6P08_05880	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
C6P08_05885	ENOG41063PX	domain protein
C6P08_05900	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
C6P08_05905	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C6P08_05910	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
C6P08_05915	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C6P08_05940	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C6P08_05945	ENOG4105BZU	Histidine kinase
C6P08_05950	ENOG4105DBI	uridine monophosphokinase
C6P08_05955	ENOG4105CN9	Peptidase m42 family protein
C6P08_05960	ENOG4108VDD	TRNA binding domain protein
C6P08_05970	ENOG4105DFU	Cell wall formation (By similarity)
C6P08_05975	ENOG4105HFZ	Membrane
C6P08_05980	ENOG4105C2M	dna polymerase I
C6P08_05985	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
C6P08_05990	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
C6P08_06015	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C6P08_06020	ENOG4105GR3	Histidine kinase
C6P08_06035	ENOG4107SC7	Inner membrane transporter yjeM
C6P08_06040	ENOG41090U3	tautomerase
C6P08_06055	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
C6P08_06060	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
C6P08_06065	ENOG4108JYZ	YitT family
C6P08_06095	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
C6P08_06100	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C6P08_06110	ENOG41080TC	multidrug resistance protein
C6P08_06120	ENOG4105DC8	reductase
C6P08_06135	ENOG4105C6K	Malic enzyme
C6P08_06140	ENOG4107ZGM	malolactic fermentation system
C6P08_06145	ENOG4105EMU	Dehydrogenase
C6P08_06150	ENOG4107QTZ	amino acid
C6P08_06160	ENOG410807C	QueT transporter
C6P08_06165	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
C6P08_06180	ENOG4106KNP	GTP-binding protein LepA C-terminus
C6P08_06190	ENOG4107R7I	amino acid
C6P08_06210	ENOG4108MK9	spermidine N(1)-acetyltransferase
C6P08_06220	ENOG4105DC8	reductase
C6P08_06225	ENOG4107QT5	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
C6P08_06230	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
C6P08_06315	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
C6P08_06330	ENOG4105K59	histidine triad (HIT) protein
C6P08_06340	ENOG4107VKM	6-phosphogluconolactonase
C6P08_06345	ENOG4105DUX	Transporter
C6P08_06380	ENOG4105D9U	N-acetyltransferase
C6P08_06385	ENOG4105EEI	dihydropteroate synthase
C6P08_06395	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
C6P08_06400	ENOG4105EUJ	GTP cyclohydrolase i
C6P08_06405	ENOG4105EUJ	GTP cyclohydrolase i
C6P08_06415	ENOG4107VKM	6-phosphogluconolactonase
C6P08_06420	ENOG4105CS2	ec 3.2.1.21
C6P08_06430	ENOG4105EBR	Carboxylesterase
C6P08_06435	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
C6P08_06440	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
C6P08_06445	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
C6P08_06455	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
C6P08_06470	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
C6P08_06475	ENOG4105C4R	Atp-dependent dna helicase
C6P08_06480	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
C6P08_06490	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
C6P08_06495	ENOG4108UKS	UPF0398 protein
C6P08_06500	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
C6P08_06505	ENOG4105BZ4	penicillin-binding protein
C6P08_06515	ENOG4105BZ1	(ABC) transporter
C6P08_06520	ENOG4105BZ1	(ABC) transporter
C6P08_06525	ENOG4105HJK	ABC transporter
C6P08_06530	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C6P08_06535	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C6P08_06540	ENOG4108JQ7	(ABC) transporter
C6P08_06545	ENOG4105C3U	ABC transporter
C6P08_06555	ENOG4105C5S	asparaginyl-tRNA synthetase
C6P08_06565	ENOG4105DVT	helicase
C6P08_06585	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
C6P08_06600	ENOG41067QW	Transcriptional regulator
C6P08_06615	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
C6P08_06620	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
C6P08_06625	ENOG4107RBJ	symporter
C6P08_06635	ENOG4105C7K	acetolactate synthase
C6P08_06640	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
C6P08_06670	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
C6P08_06685	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
C6P08_06690	ENOG4105EGD	dinuclear metal center protein, YbgI family
C6P08_06700	ENOG4107Y70	Heat shock protein
C6P08_06705	ENOG41068YB	TPR repeat-containing protein
C6P08_06735	ENOG4105EYH	Exonuclease
C6P08_06740	ENOG4107RFY	SbcCD D subunit
C6P08_06750	ENOG4105DJ2	Major Facilitator Superfamily
C6P08_06755	ENOG4105PUK	Membrane
C6P08_06960	ENOG4105K70	DNA-binding protein
C6P08_06965	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
C6P08_06970	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
C6P08_06975	ENOG4105CAT	Cytidine monophosphate kinase
C6P08_06985	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C6P08_06995	ENOG4108SAX	Membrane
C6P08_07010	ENOG4105FE9	pseudouridine synthase
C6P08_07015	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
C6P08_07020	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
C6P08_07035	ENOG4105QNR	S1 RNA binding domain protein
C6P08_07055	ENOG4107RWR	Sodium hydrogen exchanger
C6P08_07065	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
C6P08_07070	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C6P08_07075	ENOG4105C0B	DNA polymerase III (alpha subunit)
C6P08_07090	ENOG4105C5H	ABC transporter
C6P08_07095	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
C6P08_07110	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
C6P08_07115	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
C6P08_07125	ENOG4105BZU	Histidine kinase
C6P08_07130	ENOG41066F8	ROK family
C6P08_07155	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
C6P08_07160	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
C6P08_07165	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
C6P08_07170	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
C6P08_07180	ENOG4105CE9	30S ribosomal protein S2
C6P08_07185	ENOG4105VC4	domain protein
C6P08_07195	ENOG4105F6E	Acyl-transferase
C6P08_07205	ENOG4105VXM	UPF0154 protein
C6P08_07210	ENOG4105VPS	UPF0291 protein
C6P08_07215	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
C6P08_07220	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
C6P08_07225	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
C6P08_07245	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C6P08_07250	ENOG4105CFG	Acts as a chaperone (By similarity)
C6P08_07255	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C6P08_07260	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
C6P08_07310	ENOG4108RJ9	Glycosyl transferase, family 2
C6P08_07325	ENOG4105CKK	Glycosyl transferase, family 2
C6P08_07335	ENOG4105D5D	udp-galactopyranose mutase
C6P08_07365	ENOG4105D3Q	Sugar transferase
C6P08_07370	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
C6P08_07400	ENOG4107SJB	teichoic acid biosynthesis
C6P08_07410	ENOG4105EY8	ABC transporter
C6P08_07420	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
C6P08_07425	ENOG4105KPE	licD family
C6P08_07440	ENOG4107X35	defense response to bacterium
C6P08_07445	ENOG4108KGH	TRANSCRIPTIONal
C6P08_07450	ENOG4105WH5	Teichoic acid glycosylation protein
C6P08_07485	ENOG4105C88	aminopeptidase
C6P08_07505	ENOG4108YBP	pseudouridine synthase
C6P08_07520	ENOG4105PGM	cation diffusion facilitator family transporter
C6P08_07530	ENOG4105CS9	pantothenic acid kinase
C6P08_07535	ENOG4105EEM	helicase
C6P08_07545	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
C6P08_07550	ENOG4105CEV	competence damage-inducible protein
C6P08_07560	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
C6P08_07595	ENOG4105CMG	Carbohydrate kinase
C6P08_07615	ENOG4107QJZ	Glycosyl transferase, family 2
C6P08_07625	ENOG4106D4I	domain protein
C6P08_07630	ENOG4107VRP	DNA repair exonuclease
C6P08_07635	ENOG4105WZB	UPF0342 protein
C6P08_07640	ENOG4105BZ4	penicillin-binding protein
C6P08_07645	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
C6P08_07650	ENOG4105CJ3	phosphate transporter
C6P08_07655	ENOG4108Z86	Glutamine amidotransferase
C6P08_07660	ENOG4105C75	arginyL-tRNA synthetase
C6P08_07670	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
C6P08_07675	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
C6P08_07685	ENOG4105DIK	(ABC) transporter
C6P08_07690	ENOG4105CC5	ABC transporter
C6P08_07695	ENOG4108XAN	ABC transporter
C6P08_07700	ENOG4105UNS	Pfam:DUF419
C6P08_07720	ENOG4105CBD	Diacylglycerol kinase
C6P08_07725	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C6P08_07730	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C6P08_07735	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C6P08_07740	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
C6P08_07745	ENOG4108KP7	hydrolase
C6P08_07750	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
C6P08_07775	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
C6P08_07780	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
C6P08_07795	ENOG4108RVA	ribokinase
C6P08_07800	ENOG4105CPC	Aldo Keto reductase
C6P08_07805	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
C6P08_07810	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
C6P08_07820	ENOG4108JJB	ABC transporter
C6P08_07830	ENOG4105C93	Xylose Isomerase
C6P08_07835	ENOG4105FF2	Type I DHQase
C6P08_07840	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
C6P08_07845	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
C6P08_07850	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
C6P08_07855	ENOG4105D49	3-dehydroquinate synthase
C6P08_07860	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
C6P08_07865	ENOG4105E2X	shikimate dehydrogenase
C6P08_07885	ENOG4105EA8	2-Nitropropane dioxygenase
C6P08_07890	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
C6P08_07895	ENOG4108KB2	LysR family Transcriptional regulator
C6P08_07910	ENOG4105E2K	Glycosyl transferase (Group 1
C6P08_07930	ENOG4107URF	beta-phospho-glucomutase
C6P08_07940	ENOG4108IUK	alpha amylase, catalytic
C6P08_07950	ENOG4105FKQ	transcriptional regulator
C6P08_07955	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C6P08_07960	ENOG4105C19	ABC transporter
C6P08_07975	ENOG4105CZV	ABC transporter
C6P08_07980	ENOG4105FDP	GntR family transcriptional regulator
C6P08_07990	ENOG4105CHM	Aminotransferase
C6P08_08000	ENOG4107T66	Releases the N-terminal proline from various substrates (By similarity)
C6P08_08005	ENOG4108J59	Extracellular solute-binding protein, family 5
C6P08_08020	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
C6P08_08025	ENOG4105CHM	Aminotransferase
C6P08_08030	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
C6P08_08035	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C6P08_08050	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
C6P08_08055	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C6P08_08060	ENOG4105CFH	Aspartokinase
C6P08_08070	ENOG4105ETE	Transcriptional regulator (LacI family
C6P08_08090	ENOG4107RPQ	ABC transporter
C6P08_08095	ENOG4108Z6X	(sortase) family
C6P08_08100	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
C6P08_08105	ENOG4105FDU	atp-dependent rna helicase
C6P08_08110	ENOG4105EE0	oxidoreductase
C6P08_08115	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C6P08_08125	ENOG4108V0P	LemA family
C6P08_08135	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
C6P08_08145	ENOG4105E66	phosphoriboisomerase A
C6P08_08155	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
C6P08_08160	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
C6P08_08165	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
C6P08_08175	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C6P08_08180	ENOG4105CHR	reductase
C6P08_08185	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
C6P08_08190	ENOG4105EA8	2-Nitropropane dioxygenase
C6P08_08195	ENOG410854A	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C6P08_08200	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
C6P08_08205	ENOG4105NTK	Transcriptional repressor Mpra
C6P08_08210	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
C6P08_08220	ENOG4105C83	adenylosuccinate lyase
C6P08_08230	ENOG4108KGH	TRANSCRIPTIONal
C6P08_08235	ENOG4105D4A	Cell wall formation (By similarity)
C6P08_08260	ENOG4108SHN	Glycosyl transferase, family 2
C6P08_08265	ENOG4107XU6	Glycosyl transferase (Group 1
C6P08_08270	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
C6P08_08275	ENOG4105D3Q	Sugar transferase
C6P08_08280	ENOG4107YJ4	chain length determinant protein
C6P08_08290	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
C6P08_08295	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
C6P08_08300	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
C6P08_08305	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
C6P08_08310	ENOG4105C34	Pseudouridine synthase
C6P08_08320	ENOG4105VND	Ribonuclease
C6P08_08325	ENOG4105DFD	Na H antiporter
C6P08_08360	ENOG4105CTD	carboxy-peptidase
C6P08_08365	ENOG4105C85	amino acid
C6P08_08385	ENOG4108ZQX	ybak prolyl-trna synthetase
C6P08_08395	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
C6P08_08405	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
C6P08_08410	ENOG4105BZ1	(ABC) transporter
C6P08_08420	ENOG4105DND	Transcriptional regulator
C6P08_08425	ENOG4108UQV	Membrane
C6P08_08430	ENOG4105BZA	Phosphoglycerate kinase
C6P08_08435	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
C6P08_08470	ENOG4105ZT7	DNA-entry nuclease
C6P08_08490	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
C6P08_08500	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
C6P08_08515	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C6P08_08525	ENOG4105F3R	pts system mannose fructose sorbose family iid
C6P08_08530	ENOG4105ETZ	PTS System
C6P08_08540	ENOG4108IJ0	Aspartate ammonia-lyase
C6P08_08610	ENOG4105E0M	Sulfatase
C6P08_08625	ENOG4105W2C	Glycosyl transferase
C6P08_08630	ENOG4105BZF	Glycosyl transferase (Group 1
C6P08_08640	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
C6P08_08645	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
C6P08_08650	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
C6P08_08655	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
C6P08_08660	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
C6P08_08665	ENOG4105CD3	dihydroorotase
C6P08_08670	ENOG4105CXT	aspartate transcarbamylase
C6P08_08695	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
C6P08_08700	ENOG4107U5W	ybbr family
C6P08_08710	ENOG4105EEQ	Na H antiporter
C6P08_08715	ENOG4105D4A	Cell wall formation (By similarity)
C6P08_08720	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
C6P08_08725	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
C6P08_08730	ENOG4105K8N	protein family UPF0079, ATPase
C6P08_08735	ENOG4108IJ2	phosphate acetyltransferase
C6P08_08750	ENOG410839T	multidrug resistance protein
C6P08_08755	ENOG41080TC	multidrug resistance protein
C6P08_08760	ENOG4105CDA	abc transporter atp-binding protein
C6P08_08765	ENOG4105E5Q	amino acid AbC transporter
C6P08_08770	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
C6P08_08775	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
C6P08_08785	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C6P08_08795	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C6P08_08800	ENOG4105VUF	Transcriptional regulator
C6P08_08805	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
C6P08_08820	ENOG4105CP7	Triose-phosphate isomerase
C6P08_08825	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
C6P08_08830	ENOG4105KRI	phosphocarrier protein (HPr
C6P08_08840	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
C6P08_08845	ENOG4105C3M	thioredoxin reductase
C6P08_08875	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
C6P08_08885	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
C6P08_08900	ENOG4107YZX	Universal stress protein
C6P08_08910	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
C6P08_08915	ENOG4107RUE	extracellular solute-binding protein family 1
C6P08_08920	ENOG4105D38	putrescine abc transporter
C6P08_08925	ENOG4105F38	ABC transporter, permease
C6P08_08930	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C6P08_08940	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
C6P08_08945	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
C6P08_08950	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
C6P08_08965	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
C6P08_08970	ENOG4105VJV	50s ribosomal protein L35
C6P08_08975	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
C6P08_08980	ENOG4105M7K	Involved in the transcription termination process (By similarity)
C6P08_08985	ENOG4108ZSR	alkaline shock protein
C6P08_08990	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
C6P08_09000	ENOG4107QYV	phosphohexose isomerase
C6P08_09005	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
C6P08_09015	ENOG4105CSC	Glucose uptake protein
C6P08_09020	ENOG4105BZU	Histidine kinase
C6P08_09025	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C6P08_09030	ENOG4105C7H	Helicase, RecD TraA family
C6P08_09035	ENOG4105DZC	cytosine deaminase
C6P08_09050	ENOG4105DC8	reductase
C6P08_09065	ENOG4105D64	Mechanosensitive ion channel
C6P08_09070	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
C6P08_09075	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
C6P08_09090	ENOG4105CHR	reductase
C6P08_09105	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
C6P08_09115	ENOG4108R6K	riboflavin synthase, subunit alpha
C6P08_09120	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
C6P08_09150	ENOG4105C5I	Dehydrogenase
C6P08_09170	ENOG4105M6F	mutator MutT protein
C6P08_09175	ENOG4106H3A	restriction
C6P08_09235	ENOG4108HCJ	Hydrolase
C6P08_09285	ENOG4105C19	ABC transporter
C6P08_09295	ENOG4105CHM	Aminotransferase
C6P08_09300	ENOG4105KA3	membrAne
C6P08_09305	ENOG4105CS2	ec 3.2.1.21
C6P08_09310	ENOG4105C5Y	PTS System
C6P08_09315	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
C6P08_09355	ENOG4108YYH	Nadph-dependent fmn reductase
C6P08_09385	ENOG4105MS2	ribosomal subunit Interface protein
C6P08_09400	ENOG4105CVA	phosphate
C6P08_09445	ENOG4105C2N	RNA methyltransferase TrmH family group 3
C6P08_09465	ENOG4105DA5	(ABC) transporter
C6P08_09515	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
C6P08_09520	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
C6P08_09525	ENOG4105DZP	Membrane-associated zinc metalloprotease
C6P08_09530	ENOG4105KNE	Phosphatidate cytidylyltransferase
C6P08_09535	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
C6P08_09540	ENOG4108HCJ	Hydrolase
C6P08_09615	ENOG4108RCR	degv family
C6P08_09630	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
C6P08_09635	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
C6P08_09645	ENOG4105C7N	Xanthine uracil vitamin C permease
C6P08_09650	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
C6P08_09660	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
C6P08_09670	ENOG4106HWW	Acyltransferase family
C6P08_09675	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
C6P08_09685	ENOG4105FDP	GntR family transcriptional regulator
C6P08_09690	ENOG4105CE4	GlcNAc 6-P deacetylase
C6P08_09695	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C6P08_09705	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C6P08_09715	ENOG4108HCJ	Hydrolase
C6P08_09720	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
C6P08_09725	ENOG4105DQF	Hydrolase
C6P08_09740	ENOG4105II7	pyrroline-5-carboxylate reductase
C6P08_09755	ENOG4105DFF	Rod shape-determining protein mreb
C6P08_09760	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
C6P08_09780	ENOG4105UIB	(ABC) transporter
C6P08_09785	ENOG4108JQ9	ABC transporter
C6P08_09790	ENOG4105DIH	basic membrane
C6P08_09795	ENOG4105DIH	basic membrane
C6P08_09800	ENOG4105DIH	basic membrane
C6P08_09805	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
C6P08_09815	ENOG41066UM	arsR family transcriptional regulator
C6P08_09820	ENOG4106F5Q	Membrane
C6P08_09835	ENOG4105K8R	UPF0145 protein
C6P08_09840	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C6P08_09850	ENOG4105CAY	ferredoxin--nadp reductase
C6P08_09870	ENOG4105DIH	basic membrane
C6P08_09875	ENOG4105DIH	basic membrane
C6P08_09880	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
C6P08_09885	ENOG4105WD1	Membrane
C6P08_09925	ENOG410605W	Major Facilitator
C6P08_09930	ENOG4105CDU	Replicative dna helicase
C6P08_09935	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
C6P08_09945	ENOG4108JQ7	(ABC) transporter
C6P08_09955	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C6P08_09960	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C6P08_09965	ENOG4108J59	Extracellular solute-binding protein, family 5
C6P08_09975	ENOG4105DU0	nucleoside hydrolase
C6P08_10010	ENOG4105E66	phosphoriboisomerase A
C6P08_10020	ENOG4105ETE	Transcriptional regulator (LacI family
C6P08_10025	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C6P08_10035	ENOG4105DRP	amino acid AbC transporter
C6P08_10040	ENOG4105EAD	ABC transporter
C6P08_10045	ENOG4105CT1	(ABC) transporter
C6P08_10050	ENOG4105CDA	abc transporter atp-binding protein
C6P08_10065	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
C6P08_10070	ENOG4105VKD	bioY protein
C6P08_10075	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
C6P08_10095	ENOG4107QSE	Dipeptidase
C6P08_10100	ENOG4105CT4	transporter
C6P08_10105	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
C6P08_10110	ENOG4105D9R	oxidoreductase
C6P08_10125	ENOG4105EEM	helicase
C6P08_10135	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
C6P08_10140	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C6P08_10145	ENOG4105C1J	atp-dependent rna helicase
C6P08_10180	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
C6P08_10190	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
C6P08_10220	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
C6P08_10225	ENOG410667J	hydrolase
C6P08_10230	ENOG4105DCI	Phosphohydrolase
C6P08_10240	ENOG4105C0H	protease
C6P08_10245	ENOG4105Q2H	domain protein
C6P08_10260	ENOG4105BZU	Histidine kinase
C6P08_10265	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C6P08_10300	ENOG4108UUM	single-stranded DNA-binding protein
C6P08_10305	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
C6P08_10315	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
C6P08_10325	ENOG4105DFT	pur operon repressor
C6P08_10330	ENOG4108Z4K	mutator MutT protein
C6P08_10340	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
C6P08_10345	ENOG410605W	Major Facilitator
C6P08_10355	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
C6P08_10360	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
C6P08_10365	ENOG4107QSE	Dipeptidase
C6P08_10370	ENOG4107R7I	amino acid
C6P08_10380	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
C6P08_10390	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C6P08_10395	ENOG4105C28	cystathionine
C6P08_10415	ENOG4105CG5	Glycosyl transferase (Group 1
C6P08_10420	ENOG4105C8T	Leucyl-tRNA synthetase
C6P08_10425	ENOG410841Q	phosphoesterase PA-phosphatase related protein
C6P08_10435	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C6P08_10450	ENOG4105E0X	reductase
C6P08_10455	ENOG4105WH5	Teichoic acid glycosylation protein
C6P08_10460	ENOG4105DIH	basic membrane
C6P08_10475	ENOG4105E4P	ATPase (AAA
C6P08_10505	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
C6P08_10510	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
C6P08_10525	ENOG4105D5T	phosphonate abc transporter
C6P08_10540	ENOG4107104	thymidine kinase
C6P08_10550	ENOG4108KGH	TRANSCRIPTIONal
C6P08_10565	ENOG4108STX	response regulator
C6P08_10585	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
C6P08_10590	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C6P08_10595	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
C6P08_10600	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
C6P08_10605	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
C6P08_10610	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
C6P08_10615	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
C6P08_10620	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
C6P08_10625	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
C6P08_10630	ENOG4108W76	histidinol phosphate phosphatase hisj family
C6P08_10710	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
C6P08_10720	ENOG4105DAA	L-lactate
C6P08_10725	ENOG4107QM2	Aldo Keto reductase
C6P08_10730	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
C6P08_10735	ENOG4105C2W	permease
C6P08_10750	ENOG4105DC8	reductase
C6P08_10755	ENOG4108ZGC	gaf domain protein
C6P08_10775	ENOG4105CM2	brancheD-chain amino acid aminotransferase
C6P08_10785	ENOG4107S6X	Glycosyl transferase, family 2
C6P08_10820	ENOG4108RYK	Nad-dependent epimerase dehydratase
C6P08_10845	ENOG4106KNT	transcriptional regulator
C6P08_10860	ENOG4107BMA	Transglycosylase associated protein
C6P08_10925	ENOG4105CRK	lysyL-tRNA synthetase
C6P08_10930	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
C6P08_10940	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
C6P08_10955	ENOG41082I2	s4 domain protein
C6P08_10965	ENOG4108JA2	transcriptioN-repair coupling factor
C6P08_10970	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
C6P08_10980	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
C6P08_10990	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
C6P08_10995	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
C6P08_11000	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
C6P08_11005	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
C6P08_11010	ENOG4105ECB	domain protein
C6P08_11015	ENOG4105EJ2	Transcriptional regulator
C6P08_11030	ENOG4105CK1	PTS System
C6P08_11035	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C6P08_11045	ENOG4105CMG	Carbohydrate kinase
C6P08_11050	ENOG4105C93	Xylose Isomerase
C6P08_11060	ENOG4105CT4	transporter
C6P08_11065	ENOG4105DSG	hydrolase family 43
C6P08_11070	ENOG4107QNK	)-transporter
C6P08_11090	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
C6P08_11110	ENOG41067S9	phage shock protein C, PspC
C6P08_11120	ENOG4108KGH	TRANSCRIPTIONal
C6P08_11125	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
C6P08_11130	ENOG4108UK2	deaminase
C6P08_11135	ENOG4105W42	Veg protein
C6P08_11140	ENOG4105C37	(CBS) domain
C6P08_11145	ENOG4105C37	(CBS) domain
C6P08_11155	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
C6P08_11160	ENOG4105F8V	Hydrolase, tatD family
C6P08_11175	ENOG4105EEQ	Na H antiporter
C6P08_11180	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
C6P08_11210	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
C6P08_11230	ENOG4105E0M	Sulfatase
C6P08_11235	ENOG41082BV	acetyltransferase
C6P08_11245	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C6P08_11250	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C6P08_11255	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
C6P08_11260	ENOG410848D	S4 domain protein YaaA
C6P08_11265	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
C6P08_11290	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C6P08_11295	ENOG41067QW	Transcriptional regulator
C6P08_11345	ENOG4105VBF	alkaline shock protein
C6P08_11360	ENOG4107BMA	Transglycosylase associated protein