locus-tag	class	description
FGL75_00010	ENOG4105KTH	gatB Yqey
FGL75_00015	ENOG4105VCC	30S ribosomal protein S21
FGL75_00020	ENOG4107AYK	membrAne
FGL75_00025	ENOG4105C9M	aspartyl-trna synthetase
FGL75_00030	ENOG4105CUT	histidyl-tRNA synthetase
FGL75_00035	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
FGL75_00045	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
FGL75_00050	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
FGL75_00080	ENOG41082SX	arsR family transcriptional regulator
FGL75_00090	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
FGL75_00100	ENOG4105E2A	Dehydrogenase
FGL75_00105	ENOG4105VUF	Transcriptional regulator
FGL75_00140	ENOG4105MKU	Transcriptional regulator
FGL75_00145	ENOG4108JPW	Aminotransferase
FGL75_00150	ENOG4105D5Q	Arginine ornithine antiporter
FGL75_00155	ENOG4105ETE	Transcriptional regulator (LacI family
FGL75_00160	ENOG4105DC7	peptidase M24
FGL75_00175	ENOG4105DPN	Oligoendopeptidase f
FGL75_00185	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
FGL75_00190	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
FGL75_00220	ENOG410667J	hydrolase
FGL75_00225	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
FGL75_00230	ENOG4105ZMH	deoxynucleoside kinase
FGL75_00245	ENOG41069HH	4-oxalocrotonate tautomerase
FGL75_00250	ENOG4107AYK	membrAne
FGL75_00260	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
FGL75_00265	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
FGL75_00280	ENOG4105K5M	30s ribosomal protein S16
FGL75_00285	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FGL75_00295	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FGL75_00300	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
FGL75_00305	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
FGL75_00310	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FGL75_00315	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
FGL75_00320	ENOG4105CB5	ATP-dependent DNA helicase recG
FGL75_00325	ENOG4105DP4	dak2 domain fusion protein ylov
FGL75_00335	ENOG4105VB9	50S ribosomal protein l28
FGL75_00345	ENOG4105DJV	ribulose-phosphate 3-epimerase
FGL75_00355	ENOG4105D9P	serine threonine protein kinase
FGL75_00360	ENOG4108ZF3	Phosphatase
FGL75_00365	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
FGL75_00370	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
FGL75_00375	ENOG4105C25	Primosomal protein n'
FGL75_00410	ENOG4108VAU	general secretion pathway protein G
FGL75_00425	ENOG4105C7N	Xanthine uracil vitamin C permease
FGL75_00430	ENOG4105CDY	transcriptional regulatory protein
FGL75_00435	ENOG4105C7H	Helicase, RecD TraA family
FGL75_00445	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FGL75_00450	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
FGL75_00470	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
FGL75_00475	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
FGL75_00485	ENOG41087KY	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
FGL75_00490	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
FGL75_00495	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
FGL75_00500	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
FGL75_00505	ENOG4105CJN	penicillin-binding protein
FGL75_00515	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
FGL75_00520	ENOG4108V6E	Cell division protein mraZ
FGL75_00530	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
FGL75_00535	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
FGL75_00540	ENOG4105CA9	Pyruvate kinase
FGL75_00545	ENOG4108IQI	permease
FGL75_00555	ENOG4105CKU	formyltetrahydrofolate synthetase
FGL75_00560	ENOG4105EAB	amino acid AbC transporter
FGL75_00565	ENOG4105CDA	abc transporter atp-binding protein
FGL75_00570	ENOG4105E5Q	amino acid AbC transporter
FGL75_00585	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
FGL75_00590	ENOG4105DFF	Rod shape-determining protein mreb
FGL75_00595	ENOG4105W5Q	DNA repair protein (RadC
FGL75_00610	ENOG4106A8V	Protein CrcB homolog
FGL75_00615	ENOG4105WMR	Protein CrcB homolog
FGL75_00625	ENOG4105C7J	ABC transporter, permease
FGL75_00640	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FGL75_00645	ENOG4105WAZ	(Glutaredoxin-like protein) NrdH
FGL75_00675	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
FGL75_00685	ENOG4108YZ4	nudix hydrolase
FGL75_00690	ENOG4105VEQ	Cold shock protein
FGL75_00710	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
FGL75_00715	ENOG4108JJ8	(ABC) transporter
FGL75_00720	ENOG4108JJ9	ABC, transporter
FGL75_00725	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
FGL75_00730	ENOG4105C4M	(Ubiquinol oxidase) subunit I
FGL75_00845	ENOG4105BZM	domain protein
FGL75_00855	ENOG4105DQR	SNARE associated Golgi
FGL75_00860	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
FGL75_00865	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
FGL75_00870	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
FGL75_00875	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
FGL75_00880	ENOG4105DX0	Hemolysin A
FGL75_00890	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FGL75_00895	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FGL75_00900	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
FGL75_00905	ENOG4108V7D	UPF0397 protein
FGL75_00915	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
FGL75_00920	ENOG4105C22	threonyL-tRNA synthetase
FGL75_00925	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
FGL75_00930	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
FGL75_00945	ENOG4105CDE	UPF0348 protein
FGL75_00960	ENOG4108WF2	Metal Dependent Phosphohydrolase
FGL75_00965	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
FGL75_00975	ENOG4105CQW	ribosome biogenesis GTPase YqeH
FGL75_00995	ENOG4105C0X	amino acid
FGL75_01000	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
FGL75_01005	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
FGL75_01010	ENOG4105C5H	ABC transporter
FGL75_01015	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
FGL75_01020	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
FGL75_01030	ENOG4108UT2	hemolysin iii
FGL75_01045	ENOG4107YZX	Universal stress protein
FGL75_01055	ENOG4105D1H	recombination factor protein RarA
FGL75_01070	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
FGL75_01075	ENOG4105EVI	UPF0374 protein
FGL75_01080	ENOG410902V	Modulates RecA activity (By similarity)
FGL75_01085	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
FGL75_01090	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FGL75_01095	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FGL75_01100	ENOG4105E2Z	phosphate ABC transporter (Permease
FGL75_01105	ENOG4105C8U	phosphate abc transporter
FGL75_01110	ENOG4105CVA	phosphate
FGL75_01120	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
FGL75_01125	ENOG4105MMD	transcriptional regulator
FGL75_01130	ENOG4107R8B	5'-nucleotidase
FGL75_01145	ENOG4105DC7	peptidase M24
FGL75_01150	ENOG4105DTQ	mandelate racemase muconate lactonizing
FGL75_01155	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
FGL75_01160	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
FGL75_01165	ENOG4105E4F	Isochorismate synthase
FGL75_01210	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FGL75_01225	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FGL75_01230	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FGL75_01265	ENOG4105K46	50S ribosomal protein l27
FGL75_01300	ENOG4105C5F	glutamine synthetase
FGL75_01305	ENOG4105KV4	Transcriptional regulator
FGL75_01315	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
FGL75_01335	ENOG4105DKQ	ROK family
FGL75_01350	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
FGL75_01355	ENOG4107RF6	penicillin-binding protein
FGL75_01365	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
FGL75_01370	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FGL75_01380	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
FGL75_01385	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
FGL75_01400	ENOG4105CSC	Glucose uptake protein
FGL75_01410	ENOG4108RWN	rrna methyltransferase
FGL75_01420	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
FGL75_01425	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
FGL75_01430	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FGL75_01435	ENOG4105CTP	PilT protein domain protein
FGL75_01445	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
FGL75_01455	ENOG4105K4H	Nlp p60 protein
FGL75_01460	ENOG41068JE	domain protein
FGL75_01465	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FGL75_01470	ENOG4105CIS	alcohol dehydrogenase
FGL75_01475	ENOG4107FQX	Alpha-acetolactate decarboxylase
FGL75_01510	ENOG4105C5I	Dehydrogenase
FGL75_01515	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
FGL75_01520	ENOG4105CIE	May be required for sporulation (By similarity)
FGL75_01525	ENOG4105CHW	UPF0052 protein
FGL75_01530	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
FGL75_01540	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
FGL75_01565	ENOG4108RG0	uracil-dna glycosylase
FGL75_01570	ENOG4105CG3	alpha amylase, catalytic region
FGL75_01580	ENOG4105CMG	Carbohydrate kinase
FGL75_01590	ENOG4105DT3	PTS system, galactitol-specific IIc component
FGL75_01615	ENOG4105CPC	Aldo Keto reductase
FGL75_01640	ENOG4105CVA	phosphate
FGL75_01655	ENOG4105EZV	Transcriptional regulator
FGL75_01665	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
FGL75_01670	ENOG4105CP7	Triose-phosphate isomerase
FGL75_01680	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
FGL75_01685	ENOG4105C6F	GntR Family Transcriptional Regulator
FGL75_01690	ENOG4105C6Z	Gluconate
FGL75_01695	ENOG4108UHU	Aldolase
FGL75_01705	ENOG4105CXK	mandelate racemase muconate lactonizing
FGL75_01735	ENOG4107PP3	Acetylornithine deacetylase
FGL75_01760	ENOG4108UJD	30S ribosomal protein S9
FGL75_01765	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
FGL75_01770	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
FGL75_01780	ENOG4108JJB	ABC transporter
FGL75_01785	ENOG4108JJB	ABC transporter
FGL75_01800	ENOG4105DSE	periplasmic solute binding protein
FGL75_01805	ENOG4105CC5	ABC transporter
FGL75_01810	ENOG4105DIK	(ABC) transporter
FGL75_01820	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
FGL75_01825	ENOG4108VZM	50s ribosomal protein L10
FGL75_01830	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
FGL75_01835	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
FGL75_01840	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
FGL75_01850	ENOG4107FTN	50S ribosomal protein L33
FGL75_01865	ENOG4105C2N	RNA methyltransferase TrmH family group 3
FGL75_01870	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FGL75_01875	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
FGL75_01880	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
FGL75_01885	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
FGL75_01890	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
FGL75_01895	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
FGL75_01900	ENOG4105CD3	dihydroorotase
FGL75_01905	ENOG4105CXT	aspartate transcarbamylase
FGL75_01910	ENOG4105C2X	Arabinose 5-phosphate isomerase
FGL75_01915	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
FGL75_01920	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
FGL75_01925	ENOG4105C8N	cysteinyl-tRNA synthetase
FGL75_01930	ENOG4105CPC	Aldo Keto reductase
FGL75_01935	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
FGL75_01940	ENOG4105DAP	Nicotinate phosphoribosyltransferase
FGL75_01950	ENOG4105D01	(LipO)protein
FGL75_01955	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
FGL75_01960	ENOG4108UMI	ABC transporter, permease
FGL75_01985	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FGL75_01990	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
FGL75_02005	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
FGL75_02010	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
FGL75_02015	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
FGL75_02020	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
FGL75_02025	ENOG4105VPB	50S ribosomal protein L30
FGL75_02030	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
FGL75_02040	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
FGL75_02045	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
FGL75_02050	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FGL75_02055	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
FGL75_02060	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
FGL75_02065	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
FGL75_02070	ENOG41082SA	50s ribosomal protein l29
FGL75_02075	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
FGL75_02080	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
FGL75_02085	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
FGL75_02095	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FGL75_02100	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
FGL75_02105	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
FGL75_02110	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
FGL75_02115	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
FGL75_02120	ENOG4105EAH	synthase
FGL75_02125	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FGL75_02140	ENOG41072GX	Peptidase M22 Glycoprotease
FGL75_02145	ENOG4105CMR	udp-glucose 4-epimerase
FGL75_02155	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
FGL75_02165	ENOG4105X0R	protein from nitrogen regulatory protein P-II
FGL75_02170	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
FGL75_02180	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
FGL75_02190	ENOG4105C6E	dna polymerase iii
FGL75_02205	ENOG4107Y49	methyltransferase
FGL75_02215	ENOG4105C5H	ABC transporter
FGL75_02225	ENOG41082BM	Transcriptional regulator, arsr family
FGL75_02235	ENOG4107QNK	)-transporter
FGL75_02240	ENOG41067S9	phage shock protein C, PspC
FGL75_02245	ENOG4107PP3	Acetylornithine deacetylase
FGL75_02265	ENOG4105DHI	Methyltransferase
FGL75_02270	ENOG4107QW4	alcohol dehydrogenase
FGL75_02275	ENOG4107QW4	alcohol dehydrogenase
FGL75_02285	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FGL75_02290	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FGL75_02295	ENOG4105KEX	transcriptional regulator, ctsr
FGL75_02320	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
FGL75_02325	ENOG4105ZMH	deoxynucleoside kinase
FGL75_02330	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
FGL75_02335	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
FGL75_02340	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
FGL75_02345	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
FGL75_02350	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FGL75_02355	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
FGL75_02360	ENOG4105WS6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FGL75_02380	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
FGL75_02385	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FGL75_02390	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
FGL75_02400	ENOG4107104	thymidine kinase
FGL75_02405	ENOG4105F1K	Glutamine amidotransferase
FGL75_02410	ENOG4105DMS	mur ligase
FGL75_02430	ENOG4105CPN	adenine deaminase
FGL75_02435	ENOG4105C7N	Xanthine uracil vitamin C permease
FGL75_02440	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
FGL75_02445	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
FGL75_02450	ENOG4105BZ1	(ABC) transporter
FGL75_02455	ENOG4105BZ1	(ABC) transporter
FGL75_02465	ENOG4105VZJ	PTS System
FGL75_02470	ENOG4105CK1	PTS System
FGL75_02475	ENOG4105CS2	ec 3.2.1.21
FGL75_02480	ENOG4105VCP	PTS System
FGL75_02485	ENOG4105VZJ	PTS System
FGL75_02490	ENOG4105CS2	ec 3.2.1.21
FGL75_02495	ENOG4108S3Y	transcriptional regulator
FGL75_02500	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
FGL75_02520	ENOG4105CGK	Exodeoxyribonuclease III
FGL75_02525	ENOG4108EKI	Dehydrogenase
FGL75_02530	ENOG4105C59	p-type ATPase
FGL75_02545	ENOG4105NA0	Transcriptional regulator
FGL75_02550	ENOG4105C9K	Endothelin-converting enzyme 1
FGL75_02560	ENOG4107QRI	Phosphoketolase
FGL75_02565	ENOG4108TZY	GntR Family Transcriptional Regulator
FGL75_02585	ENOG4105E5Q	amino acid AbC transporter
FGL75_02610	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
FGL75_02640	ENOG4107QNK	)-transporter
FGL75_02645	ENOG4105C5H	ABC transporter
FGL75_02655	ENOG4105FDK	ABC transporter
FGL75_02670	ENOG4105EXC	Acyl-transferase
FGL75_02690	ENOG4105DUX	Transporter
FGL75_02720	ENOG410841Q	phosphoesterase PA-phosphatase related protein
FGL75_02730	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FGL75_02740	ENOG4105C3G	gtp-binding protein
FGL75_02750	ENOG4105FA0	parb-like partition protein
FGL75_02755	ENOG4107QJE	Chromosome Partitioning Protein
FGL75_02770	ENOG4105CEN	a g-specific adenine glycosylase
FGL75_02775	ENOG4105E66	phosphoriboisomerase A
FGL75_02780	ENOG4105US7	Histidine kinase
FGL75_02785	ENOG4108STX	response regulator
FGL75_02790	ENOG4107QTZ	amino acid
FGL75_02800	ENOG4105CEY	Amp-dependent synthetase and ligase
FGL75_02805	ENOG4108IPT	Naphthoate synthase
FGL75_02820	ENOG4105VEM	Conserved domain protein
FGL75_02825	ENOG4105HDK	L-asparaginase
FGL75_02845	ENOG4107R7I	amino acid
FGL75_02850	ENOG4105CPQ	Dehydrogenase
FGL75_02855	ENOG4108W5N	phosphatidylglycerophosphatase a
FGL75_02860	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
FGL75_02870	ENOG4107U9W	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX (By similarity)
FGL75_02880	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FGL75_02885	ENOG4108EQA	pts system
FGL75_02895	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
FGL75_02900	ENOG4105F3R	pts system mannose fructose sorbose family iid
FGL75_02915	ENOG4105FDP	GntR family transcriptional regulator
FGL75_02920	ENOG4105FDP	GntR family transcriptional regulator
FGL75_02925	ENOG4105CUB	amino acid
FGL75_02940	ENOG4105HMI	Membrane
FGL75_02945	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
FGL75_02960	ENOG4105C26	Dehydrogenase
FGL75_03015	ENOG4105C85	amino acid
FGL75_03030	ENOG4105C02	permease
FGL75_03045	ENOG4105EAB	amino acid AbC transporter
FGL75_03050	ENOG4105E5Q	amino acid AbC transporter
FGL75_03055	ENOG4105CDA	abc transporter atp-binding protein
FGL75_03075	ENOG4105CHM	Aminotransferase
FGL75_03080	ENOG4105CQB	FAD linked oxidase domain protein
FGL75_03085	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
FGL75_03090	ENOG4108JJB	ABC transporter
FGL75_03095	ENOG4108V7D	UPF0397 protein
FGL75_03100	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
FGL75_03110	ENOG4105DIH	basic membrane
FGL75_03115	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FGL75_03125	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
FGL75_03130	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
FGL75_03135	ENOG4105BZC	d-serine deaminase
FGL75_03150	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
FGL75_03170	ENOG4107TXC	Transcriptional regulator
FGL75_03175	ENOG41079KZ	Major Facilitator Superfamily
FGL75_03200	ENOG4105CXY	transporter
FGL75_03210	ENOG4107QUY	Guanine deaminase
FGL75_03215	ENOG41080Y5	BioY family
FGL75_03230	ENOG4105CMG	Carbohydrate kinase
FGL75_03245	ENOG4107RBJ	symporter
FGL75_03255	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
FGL75_03260	ENOG4105DU0	nucleoside hydrolase
FGL75_03280	ENOG4105FKQ	transcriptional regulator
FGL75_03285	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
FGL75_03290	ENOG4105KIS	phospholipid-binding protein
FGL75_03295	ENOG4105C5I	Dehydrogenase
FGL75_03300	ENOG4105CHM	Aminotransferase
FGL75_03310	ENOG4108UW5	maltose o-acetyltransferase
FGL75_03315	ENOG4108UW5	maltose o-acetyltransferase
FGL75_03320	ENOG4105F4P	)-transporter
FGL75_03330	ENOG4107QTZ	amino acid
FGL75_03345	ENOG4105CHM	Aminotransferase
FGL75_03355	ENOG4105C7N	Xanthine uracil vitamin C permease
FGL75_03370	ENOG4105CZV	ABC transporter
FGL75_03375	ENOG4107YCY	Transcriptional regulator
FGL75_03380	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FGL75_03385	ENOG4108HCJ	Hydrolase
FGL75_03395	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
FGL75_03415	ENOG4105ENX	hydrolase
FGL75_03420	ENOG4105EMU	Dehydrogenase
FGL75_03425	ENOG4105VUF	Transcriptional regulator
FGL75_03430	ENOG4105CK2	sodium dicarboxylate symporter
FGL75_03435	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
FGL75_03440	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
FGL75_03445	ENOG4105D06	uba thif-type nad fad binding protein
FGL75_03465	ENOG4105C85	amino acid
FGL75_03470	ENOG4107ZYR	domain protein
FGL75_03475	ENOG4106ST0	Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity)
FGL75_03495	ENOG4105E0A	ABC, transporter
FGL75_03505	ENOG4105C3F	Signal peptidase i
FGL75_03510	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FGL75_03515	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
FGL75_03520	ENOG4105VG0	50S ribosomal protein l34
FGL75_03525	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
FGL75_03530	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
FGL75_03535	ENOG410848D	S4 domain protein YaaA
FGL75_03540	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
FGL75_03545	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FGL75_03555	ENOG4105CHR	reductase
FGL75_03560	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
FGL75_03565	ENOG4108UMI	ABC transporter, permease
FGL75_03580	ENOG4105EYF	MMPL domain protein
FGL75_03595	ENOG4105E0M	Sulfatase
FGL75_03615	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
FGL75_03650	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
FGL75_03655	ENOG4105EEQ	Na H antiporter
FGL75_03660	ENOG4105F8V	Hydrolase, tatD family
FGL75_03665	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
FGL75_03670	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
FGL75_03675	ENOG4105C37	(CBS) domain
FGL75_03680	ENOG4105C37	(CBS) domain
FGL75_03685	ENOG4105W42	Veg protein
FGL75_03690	ENOG4108UK2	deaminase
FGL75_03695	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
FGL75_03700	ENOG4108KGH	TRANSCRIPTIONal
FGL75_03730	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
FGL75_03775	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FGL75_03785	ENOG4105E0A	ABC, transporter
FGL75_03800	ENOG410667J	hydrolase
FGL75_03840	ENOG4105ER6	polysaccharide biosynthesis protein
FGL75_03860	ENOG4105ECB	domain protein
FGL75_03865	ENOG4105DU1	integral membrane protein, terc
FGL75_03875	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
FGL75_03880	ENOG4108JA2	transcriptioN-repair coupling factor
FGL75_03890	ENOG41082I2	s4 domain protein
FGL75_03915	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
FGL75_03920	ENOG4105CRK	lysyL-tRNA synthetase
FGL75_03965	ENOG4105CB5	ATP-dependent DNA helicase recG
FGL75_04125	ENOG4105K5M	30s ribosomal protein S16
FGL75_04235	ENOG4105K56	Transcriptional regulator
FGL75_04240	ENOG4107QN2	dihydrolipoyl dehydrogenase
FGL75_04245	ENOG4105CPQ	Dehydrogenase
FGL75_04250	ENOG4105KA3	membrAne
FGL75_04260	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
FGL75_04285	ENOG4107ZGM	malolactic fermentation system
FGL75_04290	ENOG4105C6K	Malic enzyme
FGL75_04305	ENOG4107BMA	Transglycosylase associated protein
FGL75_04315	ENOG4106KNT	transcriptional regulator
FGL75_04325	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
FGL75_04335	ENOG4105CM2	brancheD-chain amino acid aminotransferase
FGL75_04355	ENOG4105DC8	reductase
FGL75_04360	ENOG4108RWP	Major Facilitator Superfamily protein
FGL75_04365	ENOG4105C2W	permease
FGL75_04370	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
FGL75_04375	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
FGL75_04465	ENOG4105CNT	hydrolase family 2
FGL75_04470	ENOG4108IJ9	(ABC) transporter
FGL75_04475	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
FGL75_04480	ENOG4105C28	cystathionine
FGL75_04485	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
FGL75_04490	ENOG4107RGM	aldo keto reductase
FGL75_04500	ENOG4108Z6X	(sortase) family
FGL75_04510	ENOG4105KVH	Transcriptional regulator
FGL75_04515	ENOG4108Z0Z	intracellular protease Pfpi family
FGL75_04520	ENOG4105CQ4	Transcriptional regulator
FGL75_04545	ENOG4105VDH	Dihydroxyacetone kinase
FGL75_04550	ENOG4105CMT	Dihydroxyacetone kinase
FGL75_04555	ENOG4108UTZ	Dihydroxyacetone kinase
FGL75_04560	ENOG4106KNT	transcriptional regulator
FGL75_04565	ENOG4105C5Y	PTS System
FGL75_04570	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FGL75_04575	ENOG4105C7K	acetolactate synthase
FGL75_04585	ENOG4105D2N	Aldolase
FGL75_04600	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
FGL75_04605	ENOG4108V06	Glutathione peroxidase
FGL75_04615	ENOG4108YYH	Nadph-dependent fmn reductase
FGL75_04620	ENOG4105DJ2	Major Facilitator Superfamily
FGL75_04625	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
FGL75_04630	ENOG4105ETE	Transcriptional regulator (LacI family
FGL75_04635	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
FGL75_04640	ENOG4108HKT	sucrose-6-phosphate hydrolase
FGL75_04645	ENOG4105EVU	fructokinase
FGL75_04655	ENOG410841Q	phosphoesterase PA-phosphatase related protein
FGL75_04660	ENOG4105C8T	Leucyl-tRNA synthetase
FGL75_04695	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
FGL75_04700	ENOG4107R7I	amino acid
FGL75_04710	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FGL75_04715	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
FGL75_04720	ENOG410605W	Major Facilitator
FGL75_04725	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
FGL75_04735	ENOG4108Z4K	mutator MutT protein
FGL75_04740	ENOG4105DFT	pur operon repressor
FGL75_04750	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FGL75_04755	ENOG4105DU0	nucleoside hydrolase
FGL75_04760	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
FGL75_04765	ENOG4108UUM	single-stranded DNA-binding protein
FGL75_04790	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FGL75_04795	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FGL75_04805	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FGL75_04825	ENOG4105Q2H	domain protein
FGL75_04830	ENOG4105C0H	protease
FGL75_04840	ENOG4105DCI	Phosphohydrolase
FGL75_04845	ENOG410667J	hydrolase
FGL75_04850	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
FGL75_04855	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
FGL75_04860	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
FGL75_04865	ENOG4105C1J	atp-dependent rna helicase
FGL75_04870	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FGL75_04875	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
FGL75_04880	ENOG4105EEM	helicase
FGL75_04885	ENOG4105C31	Tryptophanyl-tRNA synthetase
FGL75_04895	ENOG4105D9R	oxidoreductase
FGL75_04900	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
FGL75_04910	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
FGL75_04930	ENOG4105CT1	(ABC) transporter
FGL75_04935	ENOG4105EAD	ABC transporter
FGL75_04940	ENOG4105DRP	amino acid AbC transporter
FGL75_04945	ENOG4108J59	Extracellular solute-binding protein, family 5
FGL75_04950	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FGL75_04955	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FGL75_04965	ENOG4108JQ7	(ABC) transporter
FGL75_04975	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
FGL75_04980	ENOG4105CDU	Replicative dna helicase
FGL75_04985	ENOG410605W	Major Facilitator
FGL75_04990	ENOG4107PP3	Acetylornithine deacetylase
FGL75_04995	ENOG4105WD1	Membrane
FGL75_05000	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
FGL75_05005	ENOG4105DIH	basic membrane
FGL75_05010	ENOG4105CZM	Major Facilitator
FGL75_05020	ENOG4105CAY	ferredoxin--nadp reductase
FGL75_05025	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FGL75_05085	ENOG41082JN	Transcriptional regulator
FGL75_05090	ENOG4105CH6	catalase
FGL75_05100	ENOG4105CQ4	Transcriptional regulator
FGL75_05105	ENOG4107RBJ	symporter
FGL75_05110	ENOG4105DME	alpha-galactosidase
FGL75_05120	ENOG4105CHR	reductase
FGL75_05125	ENOG4105C6Z	Gluconate
FGL75_05130	ENOG4106F5Q	Membrane
FGL75_05135	ENOG4105DIH	basic membrane
FGL75_05140	ENOG4108JQ9	ABC transporter
FGL75_05145	ENOG4105UIB	(ABC) transporter
FGL75_05155	ENOG410667J	hydrolase
FGL75_05160	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
FGL75_05165	ENOG4105DFF	Rod shape-determining protein mreb
FGL75_05180	ENOG4105II7	pyrroline-5-carboxylate reductase
FGL75_05195	ENOG4108HCJ	Hydrolase
FGL75_05205	ENOG4105CE4	GlcNAc 6-P deacetylase
FGL75_05210	ENOG4105FDP	GntR family transcriptional regulator
FGL75_05215	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
FGL75_05220	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
FGL75_05230	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
FGL75_05235	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
FGL75_05240	ENOG4105PGM	cation diffusion facilitator family transporter
FGL75_05255	ENOG4105WH5	Teichoic acid glycosylation protein
FGL75_05260	ENOG4108HCJ	Hydrolase
FGL75_05265	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
FGL75_05270	ENOG4105KNE	Phosphatidate cytidylyltransferase
FGL75_05275	ENOG4105DZP	Membrane-associated zinc metalloprotease
FGL75_05280	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
FGL75_05285	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
FGL75_05305	ENOG4105C2N	RNA methyltransferase TrmH family group 3
FGL75_05350	ENOG4105MS2	ribosomal subunit Interface protein
FGL75_05390	ENOG4105C59	p-type ATPase
FGL75_05395	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
FGL75_05405	ENOG4105C19	ABC transporter
FGL75_05415	ENOG4105EVU	fructokinase
FGL75_05460	ENOG4105VBF	alkaline shock protein
FGL75_05465	ENOG4105C6T	cysteine synthase
FGL75_05470	ENOG4105D7W	serine acetyltransferase
FGL75_05475	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
FGL75_05545	ENOG4107BMA	Transglycosylase associated protein
FGL75_05550	ENOG4105KAV	tspo and mbr like protein
FGL75_05580	ENOG4105D64	Mechanosensitive ion channel
FGL75_05595	ENOG4105DZC	cytosine deaminase
FGL75_05600	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FGL75_05605	ENOG4105BZU	Histidine kinase
FGL75_05610	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
FGL75_05615	ENOG4107QYV	phosphohexose isomerase
FGL75_05620	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
FGL75_05630	ENOG4105M7K	Involved in the transcription termination process (By similarity)
FGL75_05635	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
FGL75_05640	ENOG4105VJV	50s ribosomal protein L35
FGL75_05645	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
FGL75_05650	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
FGL75_05655	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
FGL75_05660	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FGL75_05665	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FGL75_05670	ENOG4108EG7	Binding-protein-dependent transport systems, inner membrane component
FGL75_05675	ENOG4105D38	putrescine abc transporter
FGL75_05680	ENOG4107RUE	extracellular solute-binding protein family 1
FGL75_05695	ENOG4107YZX	Universal stress protein
FGL75_05710	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
FGL75_05715	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
FGL75_05720	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
FGL75_05725	ENOG4105C3M	thioredoxin reductase
FGL75_05730	ENOG4105CVJ	phosphoglycerate mutase
FGL75_05735	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
FGL75_05745	ENOG4105KRI	phosphocarrier protein (HPr
FGL75_05750	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
FGL75_05755	ENOG4105CG3	alpha amylase, catalytic region
FGL75_05765	ENOG4105D56	permease protein
FGL75_05770	ENOG4105EG2	ABC transporter, permease
FGL75_05775	ENOG4108IJ9	(ABC) transporter
FGL75_05785	ENOG4105CP7	Triose-phosphate isomerase
FGL75_05795	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
FGL75_05805	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
FGL75_05810	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
FGL75_05815	ENOG4105E5Q	amino acid AbC transporter
FGL75_05820	ENOG4105CDA	abc transporter atp-binding protein
FGL75_05835	ENOG4108IJ2	phosphate acetyltransferase
FGL75_05845	ENOG4105K8N	protein family UPF0079, ATPase
FGL75_05850	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
FGL75_05855	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
FGL75_05860	ENOG4105D4A	Cell wall formation (By similarity)
FGL75_05865	ENOG4107SUZ	Sodium/hydrogen exchanger family
FGL75_05875	ENOG4107U5W	ybbr family
FGL75_05880	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
FGL75_05890	ENOG4105BZF	Glycosyl transferase (Group 1
FGL75_05895	ENOG4105W2C	Glycosyl transferase
FGL75_05910	ENOG4105E0M	Sulfatase
FGL75_05975	ENOG4105ETZ	PTS System
FGL75_05980	ENOG4105F3R	pts system mannose fructose sorbose family iid
FGL75_05990	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FGL75_05995	ENOG4105ZT7	DNA-entry nuclease
FGL75_06020	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FGL75_06025	ENOG4105BZA	Phosphoglycerate kinase
FGL75_06040	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
FGL75_06045	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
FGL75_06050	ENOG4108IJ8	ABC transporter
FGL75_06055	ENOG4105E90	ABC transporter
FGL75_06060	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
FGL75_06070	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
FGL75_06080	ENOG4105DFD	Na H antiporter
FGL75_06085	ENOG4105VND	Ribonuclease
FGL75_06095	ENOG4105C34	Pseudouridine synthase
FGL75_06100	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
FGL75_06105	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
FGL75_06110	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
FGL75_06115	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
FGL75_06120	ENOG4105C83	adenylosuccinate lyase
FGL75_06165	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
FGL75_06170	ENOG41067V2	Esterase lipase
FGL75_06180	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
FGL75_06190	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
FGL75_06195	ENOG410854A	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FGL75_06200	ENOG4105EA8	2-Nitropropane dioxygenase
FGL75_06205	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
FGL75_06210	ENOG4105CHR	reductase
FGL75_06215	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FGL75_06225	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
FGL75_06230	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FGL75_06235	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
FGL75_06245	ENOG4105E66	phosphoriboisomerase A
FGL75_06255	ENOG4108V0P	LemA family
FGL75_06265	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
FGL75_06275	ENOG4105EE0	oxidoreductase
FGL75_06280	ENOG4105FDU	atp-dependent rna helicase
FGL75_06285	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
FGL75_06290	ENOG4107RPQ	ABC transporter
FGL75_06305	ENOG4105ETE	Transcriptional regulator (LacI family
FGL75_06315	ENOG4105CFH	Aspartokinase
FGL75_06320	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FGL75_06325	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
FGL75_06330	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
FGL75_06340	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FGL75_06345	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
FGL75_06350	ENOG4105CHM	Aminotransferase
FGL75_06355	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
FGL75_06365	ENOG4105CHM	Aminotransferase
FGL75_06385	ENOG4105E2X	shikimate dehydrogenase
FGL75_06390	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
FGL75_06395	ENOG4105D49	3-dehydroquinate synthase
FGL75_06400	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
FGL75_06405	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
FGL75_06410	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
FGL75_06415	ENOG4105FF2	Type I DHQase
FGL75_06430	ENOG4108JJB	ABC transporter
FGL75_06435	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
FGL75_06440	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FGL75_06445	ENOG4105CPC	Aldo Keto reductase
FGL75_06450	ENOG4108W15	Protein of unknown function (DUF1456)
FGL75_06460	ENOG4105T6C	Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps
FGL75_06465	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
FGL75_06485	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
FGL75_06490	ENOG4105DQF	Hydrolase
FGL75_06495	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FGL75_06500	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
FGL75_06505	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FGL75_06510	ENOG4105CBD	Diacylglycerol kinase
FGL75_06515	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
FGL75_06535	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
FGL75_06540	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
FGL75_06545	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
FGL75_06555	ENOG4105C75	arginyL-tRNA synthetase
FGL75_06560	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
FGL75_06565	ENOG4105BZ4	penicillin-binding protein
FGL75_06570	ENOG4105WZB	UPF0342 protein
FGL75_06580	ENOG4106D4I	domain protein
FGL75_06585	ENOG4105EQI	Metal Dependent Phosphohydrolase
FGL75_06590	ENOG4105CMG	Carbohydrate kinase
FGL75_06595	ENOG410905X	membrane-flanked domain protein
FGL75_06615	ENOG4105C6Z	Gluconate
FGL75_06635	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
FGL75_06640	ENOG4105CEV	competence damage-inducible protein
FGL75_06645	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
FGL75_06650	ENOG4105EEM	helicase
FGL75_06655	ENOG4105CS9	pantothenic acid kinase
FGL75_06675	ENOG4105VEQ	Cold shock protein
FGL75_06680	ENOG4108YBP	pseudouridine synthase
FGL75_06690	ENOG4105C88	aminopeptidase
FGL75_06700	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
FGL75_06705	ENOG4105E0X	reductase
FGL75_06715	ENOG4108115	UPF0145 protein
FGL75_06720	ENOG4105KPE	licD family
FGL75_06730	ENOG4105EY8	ABC transporter
FGL75_06750	ENOG4107SJB	teichoic acid biosynthesis
FGL75_06755	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
FGL75_06775	ENOG4107SJB	teichoic acid biosynthesis
FGL75_06780	ENOG4105EQK	-acetyltransferase
FGL75_06810	ENOG4105CID	antiterminator
FGL75_06815	ENOG4105C5Y	PTS System
FGL75_06820	ENOG4105CS2	ec 3.2.1.21
FGL75_06825	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
FGL75_06840	ENOG4107RBJ	symporter
FGL75_06890	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
FGL75_06895	ENOG4105D3Q	Sugar transferase
FGL75_06915	ENOG4105D5D	udp-galactopyranose mutase
FGL75_06930	ENOG4105CKK	Glycosyl transferase, family 2
FGL75_06935	ENOG4108RJ9	Glycosyl transferase, family 2
FGL75_06960	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
FGL75_06965	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FGL75_06970	ENOG4105CFG	Acts as a chaperone (By similarity)
FGL75_06975	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FGL75_06995	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
FGL75_07000	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
FGL75_07020	ENOG4107UZV	polysaccharide biosynthesis
FGL75_07045	ENOG4108UW5	maltose o-acetyltransferase
FGL75_07050	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
FGL75_07055	ENOG4105VPS	UPF0291 protein
FGL75_07060	ENOG4105VXM	UPF0154 protein
FGL75_07065	ENOG4105F6E	Acyl-transferase
FGL75_07070	ENOG41060K3	Methyltransferase
FGL75_07075	ENOG4105VC4	domain protein
FGL75_07080	ENOG4105CE9	30S ribosomal protein S2
FGL75_07085	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
FGL75_07090	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
FGL75_07100	ENOG4108KGH	TRANSCRIPTIONal
FGL75_07105	ENOG4105BZU	Histidine kinase
FGL75_07110	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
FGL75_07120	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
FGL75_07125	ENOG4105C5H	ABC transporter
FGL75_07140	ENOG4105C0B	DNA polymerase III (alpha subunit)
FGL75_07145	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FGL75_07150	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
FGL75_07160	ENOG4107RWR	Sodium hydrogen exchanger
FGL75_07170	ENOG4105QNR	S1 RNA binding domain protein
FGL75_07185	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
FGL75_07190	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
FGL75_07195	ENOG4105FE9	pseudouridine synthase
FGL75_07200	ENOG4108SAX	Membrane
FGL75_07210	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FGL75_07220	ENOG4105CAT	Cytidine monophosphate kinase
FGL75_07225	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
FGL75_07230	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
FGL75_07235	ENOG4105K70	DNA-binding protein
FGL75_07240	ENOG4105DWF	phosphomethylpyrimidine kinase
FGL75_07245	ENOG4105PUK	Membrane
FGL75_07250	ENOG4105DJ2	Major Facilitator Superfamily
FGL75_07255	ENOG4107RH8	nuclease SbcCD subunit D
FGL75_07260	ENOG4105EYH	Exonuclease
FGL75_07275	ENOG41068YB	TPR repeat-containing protein
FGL75_07285	ENOG4105EGD	dinuclear metal center protein, YbgI family
FGL75_07295	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
FGL75_07310	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
FGL75_07315	ENOG4108NUI	synthase
FGL75_07335	ENOG4106432	Mediates binding to human platelets, possibly through a receptor-ligand interaction. Probably associated with virulence in endovascular infection (By similarity)
FGL75_07355	ENOG4108K2B	transcriptional regulator
FGL75_07360	ENOG4107RBJ	symporter
FGL75_07365	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
FGL75_07370	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
FGL75_07380	ENOG4105DC8	reductase
FGL75_07385	ENOG410807C	QueT transporter
FGL75_07390	ENOG4106KNP	GTP-binding protein LepA C-terminus
FGL75_07400	ENOG4105DME	alpha-galactosidase
FGL75_07420	ENOG4105C5I	Dehydrogenase
FGL75_07425	ENOG4105CXG	d-lactate dehydrogenase
FGL75_07435	ENOG4105EXC	Acyl-transferase
FGL75_07465	ENOG4108K79	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FGL75_07470	ENOG4105D01	(LipO)protein
FGL75_07480	ENOG4107Y70	Heat shock protein
FGL75_07485	ENOG410667J	hydrolase
FGL75_07500	ENOG4105D1Q	UPF0246 protein
FGL75_07505	ENOG4105CVJ	phosphoglycerate mutase
FGL75_07520	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
FGL75_07530	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
FGL75_07535	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
FGL75_07540	ENOG4105C8V	SAICAR synthetase
FGL75_07550	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
FGL75_07555	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
FGL75_07565	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
FGL75_07570	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
FGL75_07575	ENOG4105DC1	bifunctional purine biosynthesis protein purh
FGL75_07580	ENOG4105C12	Phosphoribosylglycinamide synthetase
FGL75_07675	ENOG4105HMI	Membrane
FGL75_07740	ENOG4105ETE	Transcriptional regulator (LacI family
FGL75_07750	ENOG4105CG3	alpha amylase, catalytic region
FGL75_07760	ENOG4105FCD	Major Facilitator
FGL75_07770	ENOG4105JH5	thiaminase II
FGL75_07775	ENOG4105DWF	phosphomethylpyrimidine kinase
FGL75_07790	ENOG41065RQ	ADP-ribosylation crystallin J1
FGL75_07800	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
FGL75_07815	ENOG4105K59	histidine triad (HIT) protein
FGL75_07825	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
FGL75_07840	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
FGL75_07845	ENOG4105C4R	Atp-dependent dna helicase
FGL75_07850	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
FGL75_07860	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
FGL75_07865	ENOG4108UKS	UPF0398 protein
FGL75_07870	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
FGL75_07885	ENOG4105C5S	asparaginyl-tRNA synthetase
FGL75_07895	ENOG4105DVT	helicase
FGL75_07900	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
FGL75_07915	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
FGL75_07920	ENOG41064MX	Tetr family transcriptional regulator
FGL75_07925	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
FGL75_07935	ENOG4105GR3	Histidine kinase
FGL75_07940	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FGL75_07965	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
FGL75_07970	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
FGL75_08020	ENOG4105KA3	membrAne
FGL75_08025	ENOG4105CIS	alcohol dehydrogenase
FGL75_08085	ENOG4105HFZ	Membrane
FGL75_08090	ENOG4105DFU	Cell wall formation (By similarity)
FGL75_08100	ENOG4108VDD	TRNA binding domain protein
FGL75_08105	ENOG4105CN9	Peptidase m42 family protein
FGL75_08115	ENOG4105BZU	Histidine kinase
FGL75_08120	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
FGL75_08130	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FGL75_08135	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
FGL75_08170	ENOG4105D85	methylase
FGL75_08235	ENOG4105EZN	Cobyrinic acid ac-diamide synthase
FGL75_08265	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FGL75_08320	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
FGL75_08330	ENOG4108IJ8	ABC transporter
FGL75_08350	ENOG4105NA0	Transcriptional regulator
FGL75_08455	ENOG4105CJ1	ABC, transporter
FGL75_08460	ENOG4105VMP	Transcriptional regulator
FGL75_08555	ENOG4107URF	beta-phospho-glucomutase
FGL75_08560	ENOG4105C71	hydrolase family 65, central catalytic
FGL75_08565	ENOG4105C5Y	PTS System
FGL75_08570	ENOG4105C5Y	PTS System
FGL75_08575	ENOG4107414	GntR family transcriptional regulator
FGL75_08580	ENOG4105ETE	Transcriptional regulator (LacI family
FGL75_08585	ENOG4108HKT	sucrose-6-phosphate hydrolase
FGL75_08590	ENOG4105C5Y	PTS System
FGL75_08600	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
FGL75_08610	ENOG4105BZU	Histidine kinase
FGL75_08635	ENOG4108J59	Extracellular solute-binding protein, family 5
FGL75_08645	ENOG4107QN2	dihydrolipoyl dehydrogenase
FGL75_08650	ENOG4105C7S	Dehydrogenase
FGL75_08660	ENOG4107RUY	(E1 component), alpha subunit
FGL75_08665	ENOG4105DF9	Lipoate-protein, ligase
FGL75_08670	ENOG41063PX	domain protein
FGL75_08675	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
FGL75_08680	ENOG4106H78	methyltransferase
FGL75_08685	ENOG4105WUC	UPF0298 protein
FGL75_08690	ENOG4105CNI	cell division protein FtsW
FGL75_08695	ENOG4105CI3	gtp-binding protein typa
FGL75_08700	ENOG4105ECY	inositol monophosphatase
FGL75_08710	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FGL75_08740	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
FGL75_08745	ENOG4105D01	(LipO)protein
FGL75_08750	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
FGL75_08765	ENOG4108IJ7	Glycine betaine
FGL75_08775	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
FGL75_08785	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FGL75_08790	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
FGL75_08800	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FGL75_08805	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
FGL75_08810	ENOG4105C79	DNA protecting protein DprA
FGL75_08815	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FGL75_08820	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
FGL75_08835	ENOG41090WU	lipolytic protein G-D-S-L family
FGL75_08840	ENOG4108RCR	degv family
FGL75_08845	ENOG4105EPR	degv family
FGL75_08855	ENOG4106N3A	copper homeostasis protein cutc
FGL75_08860	ENOG4105F23	Fibronectin-binding protein
FGL75_08865	ENOG4105DTN	riboflavin biosynthesis protein ribF
FGL75_08870	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
FGL75_08875	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
FGL75_08880	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
FGL75_08890	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
FGL75_08895	ENOG4105CHV	Transcription elongation factor NusA
FGL75_08900	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
FGL75_08905	ENOG4105CJW	magnesium transporter
FGL75_08910	ENOG4105EMS	pseudouridine synthase
FGL75_08915	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
FGL75_08935	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
FGL75_08945	ENOG4107XGZ	Hydrolase
FGL75_08995	ENOG4105K63	Thioredoxin
FGL75_09000	ENOG4105C98	muts2 protein
FGL75_09015	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
FGL75_09020	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
FGL75_09025	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
FGL75_09030	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FGL75_09045	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
FGL75_09050	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
FGL75_09055	ENOG4105TQK	DNA polymerase iii, delta' subunit
FGL75_09060	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
FGL75_09065	ENOG4105KQC	Competence protein
FGL75_09075	ENOG4105VPH	UPF0473 protein
FGL75_09080	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
FGL75_09085	ENOG4105VBH	UPF0297 protein
FGL75_09090	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
FGL75_09095	ENOG4105C1J	atp-dependent rna helicase
FGL75_09100	ENOG4105SFS	phosphoesterase RecJ domain protein
FGL75_09105	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
FGL75_09110	ENOG4105VIE	preprotein translocase, subunit YajC
FGL75_09150	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
FGL75_09160	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
FGL75_09175	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
FGL75_09180	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FGL75_09185	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
FGL75_09190	ENOG4105RHA	ABC transporter, permease
FGL75_09195	ENOG4108IUX	(ABC) transporter
FGL75_09200	ENOG4105CNU	cell division protein FtsK
FGL75_09205	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
FGL75_09215	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
FGL75_09220	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
FGL75_09225	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
FGL75_09230	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
FGL75_09235	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
FGL75_09245	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
FGL75_09270	ENOG4108C33	Resolvase
FGL75_09345	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
FGL75_09350	ENOG4108UXE	Protein tyrosine phosphatase
FGL75_09360	ENOG41083J0	(ABC) transporter
FGL75_09365	ENOG4105C4B	ABC transporter, permease
FGL75_09385	ENOG4105IJJ	transcriptional regulator, crp fnr family
FGL75_09390	ENOG4105HUF	DNA protection during starvation protein
FGL75_09430	ENOG4108UXE	Protein tyrosine phosphatase
FGL75_09455	ENOG4105KVH	Transcriptional regulator
FGL75_09460	ENOG4107RKG	DJ-1/PfpI family
FGL75_09465	ENOG4107QYV	phosphohexose isomerase
FGL75_09475	ENOG4108VA3	3-hexulose-6-phosphate synthase
FGL75_09510	ENOG4107QNK	)-transporter
FGL75_09515	ENOG4107BMA	Transglycosylase associated protein
FGL75_09530	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
FGL75_09565	ENOG4106050	phage regulatory protein, rha family
FGL75_09725	ENOG4105K63	Thioredoxin
FGL75_09735	ENOG4105CG9	aspartate racemase
FGL75_09740	ENOG4105C3M	thioredoxin reductase
FGL75_09750	ENOG4105DC8	reductase
FGL75_09805	ENOG4105HUF	DNA protection during starvation protein
FGL75_09815	ENOG4105EVU	fructokinase
FGL75_09830	ENOG4105CPQ	Dehydrogenase