locus-tag	class	description
FGL75_00010	COG1610	YqeY-like protein
FGL75_00015	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FGL75_00020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FGL75_00025	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FGL75_00030	COG0124	histidyl-tRNA synthetase
FGL75_00035	COG0860	N-Acetylmuramoyl-L-alanine amidase
FGL75_00045	COG3425	synthase
FGL75_00050	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FGL75_00080	COG0640	Transcriptional regulator
FGL75_00090	COG1028	Short-chain dehydrogenase reductase Sdr
FGL75_00100	COG1063	alcohol dehydrogenase
FGL75_00105	COG0789	Transcriptional regulator
FGL75_00110	COG0656	L-ascorbic acid biosynthetic process
FGL75_00140	COG1309	transcriptional regulator
FGL75_00150	COG0531	amino acid
FGL75_00155	COG1609	Transcriptional regulator
FGL75_00160	COG0006	proline dipeptidase activity
FGL75_00175	COG1164	Oligoendopeptidase f
FGL75_00185	COG4862	establishment of competence for transformation
FGL75_00190	COG1393	Belongs to the ArsC family
FGL75_00220	COG0561	phosphatase activity
FGL75_00225	COG1970	mechanosensitive ion channel activity
FGL75_00230	COG1428	Deoxynucleoside kinase
FGL75_00245	COG1942	4-Oxalocrotonate Tautomerase
FGL75_00250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FGL75_00260	COG0335	large ribosomal subunit rRNA binding
FGL75_00265	COG0336	Belongs to the RNA methyltransferase TrmD family
FGL75_00270	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FGL75_00275	COG0588	phosphoglycerate mutase activity
FGL75_00280	COG0228	four-way junction DNA binding
FGL75_00285	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FGL75_00295	COG0552	protein localization to endoplasmic reticulum
FGL75_00300	COG1196	nuclear chromosome segregation
FGL75_00305	COG0571	ribonuclease III activity
FGL75_00310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGL75_00315	COG0416	fatty acid biosynthetic process
FGL75_00320	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FGL75_00325	COG1461	Dihydroxyacetone kinase
FGL75_00335	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FGL75_00345	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FGL75_00350	COG1162	GTPase activity
FGL75_00355	COG2815	serine threonine protein kinase
FGL75_00355	COG0515	serine threonine protein kinase
FGL75_00360	COG0631	protein serine/threonine phosphatase activity
FGL75_00365	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FGL75_00365	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FGL75_00370	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FGL75_00375	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FGL75_00380	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FGL75_00410	COG2165	general secretion pathway protein
FGL75_00415	COG1459	type II secretion system
FGL75_00420	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FGL75_00425	COG2252	PERMEase
FGL75_00430	COG0217	transcriptional regulatory protein
FGL75_00435	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FGL75_00445	COG0588	phosphoglycerate mutase activity
FGL75_00450	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FGL75_00455	COG3599	regulation of cell shape
FGL75_00470	COG1799	cell septum assembly
FGL75_00475	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FGL75_00485	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FGL75_00490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FGL75_00495	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FGL75_00500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FGL75_00515	COG0275	rRNA processing
FGL75_00520	COG2001	Belongs to the MraZ family
FGL75_00530	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FGL75_00535	COG2264	protein methyltransferase activity
FGL75_00545	COG0833	amino acid
FGL75_00555	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FGL75_00565	COG1126	abc transporter atp-binding protein
FGL75_00570	COG0765	amino acid transport
FGL75_00585	COG1792	Involved in formation and maintenance of cell shape
FGL75_00590	COG1077	Cell shape determining protein MreB Mrl
FGL75_00595	COG2003	Belongs to the UPF0758 family
FGL75_00610	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FGL75_00615	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FGL75_00625	COG4120	Belongs to the binding-protein-dependent transport system permease family
FGL75_00640	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FGL75_00645	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FGL75_00665	COG1388	LysM domain
FGL75_00675	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FGL75_00685	COG0494	nUDIX hydrolase
FGL75_00690	COG1278	Cold shock
FGL75_00710	COG1705	Flagellar rod assembly protein muramidase FlgJ
FGL75_00710	COG3951	Flagellar rod assembly protein muramidase FlgJ
FGL75_00715	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FGL75_00720	COG4988	ABC transporter
FGL75_00725	COG1294	oxidase, subunit
FGL75_00730	COG1271	oxidase subunit
FGL75_00845	COG2183	response to ionizing radiation
FGL75_00855	COG0586	Pfam SNARE associated Golgi protein
FGL75_00865	COG0194	GDP metabolic process
FGL75_00870	COG0497	DNA recombination
FGL75_00875	COG1438	arginine binding
FGL75_00880	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FGL75_00890	COG1722	exodeoxyribonuclease VII activity
FGL75_00895	COG1570	exodeoxyribonuclease VII activity
FGL75_00900	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FGL75_00905	COG4720	Psort location CytoplasmicMembrane, score
FGL75_00915	COG0363	glucosamine-6-phosphate deaminase activity
FGL75_00920	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FGL75_00925	COG0716	FMN binding
FGL75_00930	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FGL75_00935	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FGL75_00945	COG1323	Belongs to the UPF0348 family
FGL75_00955	COG0799	negative regulation of ribosome biogenesis
FGL75_00960	COG1713	HD superfamily hydrolase involved in NAD metabolism
FGL75_00965	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FGL75_00975	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FGL75_00985	COG1181	Belongs to the D-alanine--D-alanine ligase family
FGL75_00995	COG0531	amino acid
FGL75_01000	COG0459	protein refolding
FGL75_01005	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FGL75_01010	COG0488	(ABC) transporter
FGL75_01015	COG0285	dihydrofolate synthase activity
FGL75_01020	COG0525	valine-tRNA ligase activity
FGL75_01030	COG1272	protein, Hemolysin III
FGL75_01045	COG0589	response to stress
FGL75_01055	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FGL75_01070	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FGL75_01075	COG3557	Belongs to the UPF0374 family
FGL75_01090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FGL75_01095	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FGL75_01100	COG0581	inorganic phosphate transmembrane transporter activity
FGL75_01105	COG0573	inorganic phosphate transmembrane transporter activity
FGL75_01110	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FGL75_01120	COG0647	UMP catabolic process
FGL75_01125	COG4470	Protein conserved in bacteria
FGL75_01130	COG0737	Belongs to the 5'-nucleotidase family
FGL75_01145	COG0006	proline dipeptidase activity
FGL75_01150	COG4948	Mandelate Racemase Muconate Lactonizing
FGL75_01160	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FGL75_01165	COG1169	isochorismate synthase
FGL75_01225	COG0514	ATP-dependent DNA helicase (RecQ)
FGL75_01230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FGL75_01265	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FGL75_01270	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FGL75_01300	COG0174	glutamine synthetase
FGL75_01305	COG0789	Transcriptional regulator
FGL75_01310	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FGL75_01315	COG0584	glycerophosphoryl diester phosphodiesterase
FGL75_01335	COG1940	carbohydrate kinase activity
FGL75_01345	COG0705	Rhomboid family
FGL75_01350	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FGL75_01355	COG0768	penicillin binding
FGL75_01365	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FGL75_01370	COG0514	ATP-dependent DNA helicase (RecQ)
FGL75_01375	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FGL75_01380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGL75_01380	COG0072	phenylalanine-tRNA ligase activity
FGL75_01385	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FGL75_01390	COG1733	regulation of RNA biosynthetic process
FGL75_01400	COG4975	Glucose uptake
FGL75_01410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGL75_01420	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FGL75_01435	COG4956	integral membrane protein (PIN domain superfamily)
FGL75_01445	COG0756	dUTP diphosphatase activity
FGL75_01455	COG0791	NLP P60 protein
FGL75_01460	COG1388	LysM domain
FGL75_01460	COG3942	CHAP domain
FGL75_01465	COG0542	response to heat
FGL75_01470	COG0604	alcohol dehydrogenase
FGL75_01475	COG3527	Alpha-acetolactate decarboxylase
FGL75_01480	COG0028	Belongs to the TPP enzyme family
FGL75_01510	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGL75_01515	COG0740	serine-type endopeptidase activity
FGL75_01520	COG1481	regulation of sporulation
FGL75_01525	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FGL75_01530	COG1660	Displays ATPase and GTPase activities
FGL75_01540	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FGL75_01565	COG1573	uracil-dna glycosylase
FGL75_01590	COG3775	system Galactitol-specific IIC component
FGL75_01605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGL75_01605	COG3711	transcriptional antiterminator
FGL75_01615	COG0667	Aldo Keto reductase
FGL75_01640	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FGL75_01655	COG2169	Transcriptional regulator
FGL75_01655	COG1917	Cupin 2, conserved barrel domain protein
FGL75_01665	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FGL75_01670	COG0149	triose-phosphate isomerase activity
FGL75_01680	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FGL75_01685	COG2186	Transcriptional regulator
FGL75_01690	COG2610	gluconate transmembrane transporter activity
FGL75_01695	COG0800	Aldolase
FGL75_01705	COG4948	Mandelate Racemase Muconate Lactonizing
FGL75_01720	COG4166	transmembrane transport
FGL75_01735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FGL75_01760	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FGL75_01765	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FGL75_01770	COG0101	tRNA pseudouridine synthase activity
FGL75_01780	COG1122	ATPase activity
FGL75_01785	COG1122	ATPase activity
FGL75_01795	COG1252	NADH dehydrogenase
FGL75_01800	COG0803	Belongs to the bacterial solute-binding protein 9 family
FGL75_01805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FGL75_01810	COG1121	(ABC) transporter
FGL75_01820	COG0222	ribosome binding
FGL75_01825	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FGL75_01830	COG0081	regulation of translation
FGL75_01835	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FGL75_01840	COG0250	Participates in transcription elongation, termination and antitermination
FGL75_01850	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FGL75_01865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGL75_01870	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FGL75_01875	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FGL75_01880	COG0284	orotidine-5'-phosphate decarboxylase activity
FGL75_01885	COG0167	dihydroorotate dehydrogenase activity
FGL75_01890	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FGL75_01895	COG0505	Belongs to the CarA family
FGL75_01905	COG0540	Belongs to the ATCase OTCase family
FGL75_01910	COG0517	IMP dehydrogenase activity
FGL75_01910	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FGL75_01915	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FGL75_01920	COG1854	S-ribosylhomocysteine lyase activity
FGL75_01925	COG0215	cysteine-tRNA ligase activity
FGL75_01930	COG0667	Aldo Keto reductase
FGL75_01935	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FGL75_01940	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FGL75_01950	COG1464	Belongs to the NlpA lipoprotein family
FGL75_01955	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FGL75_01980	COG0203	ribosomal protein L17
FGL75_01985	COG0202	RNA polymerase activity
FGL75_01990	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FGL75_01995	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FGL75_02000	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FGL75_02005	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FGL75_02010	COG0563	adenylate kinase activity
FGL75_02020	COG0200	Binds to the 23S rRNA
FGL75_02030	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FGL75_02035	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FGL75_02040	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FGL75_02045	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FGL75_02050	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FGL75_02055	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FGL75_02060	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FGL75_02070	COG0255	Belongs to the universal ribosomal protein uL29 family
FGL75_02075	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FGL75_02080	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FGL75_02085	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FGL75_02090	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FGL75_02095	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FGL75_02100	COG0089	rRNA binding
FGL75_02110	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FGL75_02115	COG0051	transcription antitermination factor activity, RNA binding
FGL75_02120	COG0142	geranyltranstransferase activity
FGL75_02125	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FGL75_02140	COG1214	PFAM Peptidase M22, glycoprotease
FGL75_02145	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FGL75_02165	COG3870	Protein conserved in bacteria
FGL75_02170	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FGL75_02180	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FGL75_02190	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FGL75_02205	COG2813	Specifically methylates the guanine in position
FGL75_02215	COG0488	(ABC) transporter
FGL75_02225	COG0640	Transcriptional regulator
FGL75_02235	COG2814	Major facilitator Superfamily
FGL75_02240	COG1983	PspC domain protein
FGL75_02245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FGL75_02265	COG0500	methyltransferase
FGL75_02270	COG1979	alcohol dehydrogenase
FGL75_02275	COG1979	alcohol dehydrogenase
FGL75_02280	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FGL75_02285	COG0085	RNA polymerase activity
FGL75_02290	COG0542	response to heat
FGL75_02295	COG4463	regulation of RNA biosynthetic process
FGL75_02320	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FGL75_02325	COG1428	Deoxynucleoside kinase
FGL75_02335	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FGL75_02340	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FGL75_02345	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FGL75_02350	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FGL75_02355	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FGL75_02360	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FGL75_02365	COG0356	it plays a direct role in the translocation of protons across the membrane
FGL75_02370	COG2233	PERMEase
FGL75_02380	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FGL75_02385	COG0009	L-threonylcarbamoyladenylate synthase
FGL75_02390	COG2890	protein-(glutamine-N5) methyltransferase activity
FGL75_02400	COG1435	thymidine kinase activity
FGL75_02405	COG3442	glutamine amidotransferase
FGL75_02410	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FGL75_02430	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FGL75_02435	COG2252	PERMEase
FGL75_02440	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FGL75_02450	COG1132	(ABC) transporter
FGL75_02455	COG1132	(ABC) transporter
FGL75_02465	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FGL75_02470	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FGL75_02475	COG2723	6-phospho-beta-galactosidase activity
FGL75_02480	COG1447	Phosphotransferase system cellobiose-specific component IIA
FGL75_02485	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FGL75_02490	COG2723	6-phospho-beta-galactosidase activity
FGL75_02495	COG2188	Transcriptional regulator
FGL75_02520	COG0708	Exodeoxyribonuclease III
FGL75_02525	COG1454	alcohol dehydrogenase
FGL75_02525	COG1012	belongs to the aldehyde dehydrogenase family
FGL75_02530	COG2217	Heavy metal translocating P-type atpase
FGL75_02550	COG3590	peptidase
FGL75_02560	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FGL75_02565	COG2188	Transcriptional regulator
FGL75_02570	COG1418	mRNA catabolic process
FGL75_02605	COG0656	L-ascorbic acid biosynthetic process
FGL75_02610	COG2160	L-arabinose isomerase activity
FGL75_02635	COG0534	Mate efflux family protein
FGL75_02645	COG0488	(ABC) transporter
FGL75_02655	COG1121	(ABC) transporter
FGL75_02670	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FGL75_02670	COG2755	lipolytic protein G-D-S-L family
FGL75_02690	COG3104	oligopeptide transport
FGL75_02720	COG0671	phosphoesterase, PA-phosphatase related
FGL75_02730	COG0745	RESPONSE REGULATOR receiver
FGL75_02740	COG0012	GTP binding
FGL75_02750	COG1475	DNA binding
FGL75_02755	COG1192	Involved in chromosome partitioning
FGL75_02760	COG0357	Ribosomal RNA small subunit methyltransferase G
FGL75_02770	COG1194	a g-specific adenine glycosylase
FGL75_02780	COG5002	protein histidine kinase activity
FGL75_02785	COG0745	RESPONSE REGULATOR receiver
FGL75_02790	COG0531	amino acid
FGL75_02800	COG0318	PFAM AMP-dependent synthetase and ligase
FGL75_02805	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FGL75_02820	COG4443	Transcriptional Coactivator p15 (PC4)
FGL75_02825	COG0252	asparaginase activity
FGL75_02835	COG1113	amino acid transport
FGL75_02845	COG0531	amino acid
FGL75_02855	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FGL75_02860	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FGL75_02870	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FGL75_02880	COG0477	Major facilitator Superfamily
FGL75_02885	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGL75_02885	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGL75_02900	COG3716	PTS system mannose fructose sorbose family IID component
FGL75_02915	COG2188	Transcriptional regulator
FGL75_02920	COG2188	Transcriptional regulator
FGL75_02925	COG0531	amino acid
FGL75_02940	COG2855	membrane
FGL75_02945	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FGL75_02960	COG1012	belongs to the aldehyde dehydrogenase family
FGL75_03015	COG1113	amino acid transport
FGL75_03030	COG0628	permease
FGL75_03045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGL75_03050	COG0765	amino acid transport
FGL75_03055	COG1126	abc transporter atp-binding protein
FGL75_03065	COG0656	L-ascorbic acid biosynthetic process
FGL75_03075	COG0436	Aminotransferase
FGL75_03080	COG0277	FAD linked oxidase domain protein
FGL75_03085	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FGL75_03090	COG1122	ATPase activity
FGL75_03095	COG4720	Psort location CytoplasmicMembrane, score
FGL75_03100	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGL75_03105	COG2357	RelA SpoT domain protein
FGL75_03110	COG1744	ABC transporter substrate-binding protein PnrA-like
FGL75_03135	COG3048	D-serine ammonia-lyase activity
FGL75_03150	COG1136	(ABC) transporter
FGL75_03170	COG0789	Transcriptional regulator
FGL75_03175	COG0477	Major facilitator Superfamily
FGL75_03180	COG1827	regulation of RNA biosynthetic process
FGL75_03190	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FGL75_03210	COG0402	S-adenosylhomocysteine deaminase activity
FGL75_03215	COG1268	BioY protein
FGL75_03230	COG1070	Carbohydrate kinase
FGL75_03245	COG2190	(PTS) system
FGL75_03245	COG2211	Major facilitator Superfamily
FGL75_03255	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FGL75_03280	COG1609	Transcriptional regulator
FGL75_03285	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FGL75_03290	COG1881	PFAM PEBP family protein
FGL75_03295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGL75_03300	COG0436	Aminotransferase
FGL75_03310	COG0110	maltose O-acetyltransferase activity
FGL75_03315	COG0110	maltose O-acetyltransferase activity
FGL75_03320	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FGL75_03330	COG0531	amino acid
FGL75_03355	COG2252	PERMEase
FGL75_03370	COG1131	(ABC) transporter
FGL75_03375	COG2186	Transcriptional regulator
FGL75_03380	COG0328	RNA-DNA hybrid ribonuclease activity
FGL75_03385	COG0561	phosphatase activity
FGL75_03390	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FGL75_03405	COG0028	Belongs to the TPP enzyme family
FGL75_03420	COG4221	oxidoreductase activity
FGL75_03425	COG0789	Transcriptional regulator
FGL75_03430	COG1301	dicarboxylic acid transport
FGL75_03435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FGL75_03440	COG2022	thiamine diphosphate biosynthetic process
FGL75_03445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FGL75_03465	COG1113	amino acid transport
FGL75_03470	COG0569	domain protein
FGL75_03475	COG5386	Cell surface protein
FGL75_03495	COG1120	ATPase activity
FGL75_03510	COG0706	membrane insertase activity
FGL75_03515	COG0594	ribonuclease P activity
FGL75_03520	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FGL75_03525	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FGL75_03530	COG0592	DNA-directed DNA polymerase activity
FGL75_03535	COG2501	S4 domain
FGL75_03540	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FGL75_03545	COG0187	DNA topoisomerase II activity
FGL75_03560	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FGL75_03565	COG2011	ABC-type metal ion transport system permease component
FGL75_03570	COG1464	Belongs to the NlpA lipoprotein family
FGL75_03580	COG2409	Drug exporters of the RND superfamily
FGL75_03595	COG1368	sulfuric ester hydrolase activity
FGL75_03615	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FGL75_03650	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGL75_03650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGL75_03655	COG0025	NhaP-type Na H and K H
FGL75_03660	COG0084	hydrolase, TatD family'
FGL75_03665	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FGL75_03670	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FGL75_03675	COG1253	flavin adenine dinucleotide binding
FGL75_03680	COG1253	flavin adenine dinucleotide binding
FGL75_03685	COG4466	Protein conserved in bacteria
FGL75_03690	COG2131	deaminase
FGL75_03695	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FGL75_03700	COG1316	TRANSCRIPTIONal
FGL75_03730	COG0737	Belongs to the 5'-nucleotidase family
FGL75_03785	COG1120	ATPase activity
FGL75_03800	COG0561	phosphatase activity
FGL75_03840	COG2244	polysaccharide biosynthetic process
FGL75_03860	COG1511	domain protein
FGL75_03875	COG0193	aminoacyl-tRNA hydrolase activity
FGL75_03880	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FGL75_03885	COG2244	polysaccharide biosynthetic process
FGL75_03890	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FGL75_03915	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FGL75_03920	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FGL75_04125	COG0228	four-way junction DNA binding
FGL75_04235	COG1846	Transcriptional regulator
FGL75_04240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGL75_04245	COG1063	alcohol dehydrogenase
FGL75_04250	COG3759	membrane
FGL75_04260	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FGL75_04285	COG0583	DNA-binding transcription factor activity
FGL75_04305	COG2261	transglycosylase associated protein
FGL75_04315	COG1737	Transcriptional regulator
FGL75_04320	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FGL75_04330	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FGL75_04335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FGL75_04345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FGL75_04350	COG1956	GAF domain-containing protein
FGL75_04360	COG2814	Major facilitator Superfamily
FGL75_04365	COG2233	PERMEase
FGL75_04370	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FGL75_04375	COG2084	Dehydrogenase
FGL75_04380	COG0438	transferase activity, transferring glycosyl groups
FGL75_04450	COG1175	transmembrane transport
FGL75_04465	COG3250	beta-galactosidase activity
FGL75_04470	COG3842	ATPase activity
FGL75_04475	COG1250	3-hydroxyacyl-CoA dehydrogenase
FGL75_04480	COG0626	cystathionine gamma-synthase activity
FGL75_04485	COG1088	dTDP-glucose 4,6-dehydratase activity
FGL75_04490	COG4989	oxidoreductase activity
FGL75_04500	COG3764	Sortase (surface protein transpeptidase)
FGL75_04505	COG0702	epimerase
FGL75_04510	COG1733	regulation of RNA biosynthetic process
FGL75_04515	COG0693	protein deglycase activity
FGL75_04520	COG1609	Transcriptional regulator
FGL75_04525	COG1874	Beta-galactosidase
FGL75_04540	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FGL75_04545	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FGL75_04550	COG2376	Dihydroxyacetone kinase
FGL75_04555	COG1461	Dihydroxyacetone kinase
FGL75_04560	COG1737	Transcriptional regulator
FGL75_04565	COG1263	PTS System
FGL75_04565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGL75_04570	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FGL75_04575	COG0028	Belongs to the TPP enzyme family
FGL75_04600	COG2514	catechol 2,3-dioxygenase activity
FGL75_04605	COG0386	Belongs to the glutathione peroxidase family
FGL75_04610	COG1063	alcohol dehydrogenase
FGL75_04615	COG0431	NADPH-dependent FMN reductase
FGL75_04620	COG2807	transmembrane transport
FGL75_04625	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGL75_04655	COG0671	phosphoesterase, PA-phosphatase related
FGL75_04660	COG0495	leucyl-tRNA aminoacylation
FGL75_04670	COG2244	polysaccharide biosynthetic process
FGL75_04695	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FGL75_04700	COG0531	amino acid
FGL75_04710	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FGL75_04715	COG1074	ATP-dependent DNA helicase activity
FGL75_04720	COG2814	Major facilitator Superfamily
FGL75_04725	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FGL75_04735	COG1051	belongs to the nudix hydrolase family
FGL75_04740	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FGL75_04750	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FGL75_04755	COG1957	nucleoside hydrolase
FGL75_04760	COG0360	Binds together with S18 to 16S ribosomal RNA
FGL75_04765	COG0629	single-stranded DNA binding
FGL75_04770	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FGL75_04795	COG0516	GMP reductase activity
FGL75_04795	COG0517	IMP dehydrogenase activity
FGL75_04805	COG0745	RESPONSE REGULATOR receiver
FGL75_04825	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FGL75_04830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FGL75_04840	COG1078	dGTPase activity
FGL75_04845	COG0561	phosphatase activity
FGL75_04850	COG3343	RNA polymerase activity
FGL75_04855	COG0504	CTP synthase activity
FGL75_04860	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FGL75_04875	COG2337	Toxic component of a toxin-antitoxin (TA) module
FGL75_04880	COG3973	AAA domain
FGL75_04895	COG0673	inositol 2-dehydrogenase activity
FGL75_04900	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FGL75_04910	COG0194	GDP metabolic process
FGL75_04930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGL75_04935	COG0765	amino acid transport
FGL75_04940	COG0765	amino acid transport
FGL75_04945	COG4166	transmembrane transport
FGL75_04950	COG0601	transmembrane transport
FGL75_04955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGL75_04960	COG0444	Belongs to the ABC transporter superfamily
FGL75_04965	COG4608	Belongs to the ABC transporter superfamily
FGL75_04975	COG0359	binds to the 23S rRNA
FGL75_04980	COG0305	Participates in initiation and elongation during chromosome replication
FGL75_04985	COG2814	Major facilitator Superfamily
FGL75_04990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FGL75_04995	COG2832	Protein of unknown function (DUF454)
FGL75_05005	COG1744	ABC transporter substrate-binding protein PnrA-like
FGL75_05010	COG2814	Major facilitator Superfamily
FGL75_05020	COG0492	ferredoxin-NADP+ reductase activity
FGL75_05025	COG0588	phosphoglycerate mutase activity
FGL75_05085	COG1309	transcriptional regulator
FGL75_05095	COG1064	alcohol dehydrogenase
FGL75_05100	COG1609	Transcriptional regulator
FGL75_05120	COG1028	Short-chain dehydrogenase reductase Sdr
FGL75_05125	COG2610	gluconate transmembrane transporter activity
FGL75_05130	COG0628	permease
FGL75_05135	COG1744	ABC transporter substrate-binding protein PnrA-like
FGL75_05155	COG0561	phosphatase activity
FGL75_05160	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FGL75_05165	COG1077	Cell shape determining protein MreB Mrl
FGL75_05175	COG0772	Belongs to the SEDS family
FGL75_05180	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FGL75_05195	COG0561	phosphatase activity
FGL75_05200	COG1136	(ABC) transporter
FGL75_05200	COG0577	efflux transmembrane transporter activity
FGL75_05215	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FGL75_05220	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FGL75_05230	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FGL75_05245	COG0640	Transcriptional regulator
FGL75_05255	COG2246	polysaccharide biosynthetic process
FGL75_05260	COG0561	phosphatase activity
FGL75_05265	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FGL75_05270	COG4589	Belongs to the CDS family
FGL75_05275	COG0750	zinc metalloprotease
FGL75_05280	COG0442	prolyl-tRNA aminoacylation
FGL75_05285	COG2176	DNA-directed DNA polymerase activity
FGL75_05305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGL75_05340	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FGL75_05350	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FGL75_05360	COG2183	response to ionizing radiation
FGL75_05390	COG2217	Heavy metal translocating P-type atpase
FGL75_05405	COG1136	(ABC) transporter
FGL75_05415	COG1940	carbohydrate kinase activity
FGL75_05465	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FGL75_05470	COG1045	serine acetyltransferase
FGL75_05475	COG0582	viral genome integration into host DNA
FGL75_05545	COG2261	transglycosylase associated protein
FGL75_05550	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FGL75_05575	COG0516	GMP reductase activity
FGL75_05580	COG0668	transmembrane transport
FGL75_05595	COG0402	S-adenosylhomocysteine deaminase activity
FGL75_05600	COG0745	RESPONSE REGULATOR receiver
FGL75_05605	COG5002	protein histidine kinase activity
FGL75_05605	COG3850	Histidine kinase
FGL75_05610	COG2017	converts alpha-aldose to the beta-anomer
FGL75_05620	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FGL75_05635	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FGL75_05640	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FGL75_05645	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FGL75_05650	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FGL75_05655	COG0049	tRNA binding
FGL75_05660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FGL75_05665	COG3842	ATPase activity
FGL75_05675	COG1177	transmembrane transport
FGL75_05680	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FGL75_05695	COG0589	response to stress
FGL75_05710	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FGL75_05715	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FGL75_05720	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FGL75_05725	COG0492	ferredoxin-NADP+ reductase activity
FGL75_05730	COG0406	alpha-ribazole phosphatase activity
FGL75_05735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FGL75_05745	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGL75_05765	COG1175	transmembrane transport
FGL75_05770	COG3833	ABC-type maltose transport systems, permease component
FGL75_05775	COG3842	ATPase activity
FGL75_05785	COG0149	triose-phosphate isomerase activity
FGL75_05805	COG0557	exoribonuclease II activity
FGL75_05810	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FGL75_05815	COG0765	amino acid transport
FGL75_05820	COG1126	abc transporter atp-binding protein
FGL75_05835	COG0280	phosphate acetyltransferase
FGL75_05845	COG0802	atpase or kinase
FGL75_05860	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FGL75_05865	COG0025	NhaP-type Na H and K H
FGL75_05875	COG4856	YbbR-like protein
FGL75_05880	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FGL75_05890	COG0438	transferase activity, transferring glycosyl groups
FGL75_05895	COG0438	transferase activity, transferring glycosyl groups
FGL75_05910	COG1368	sulfuric ester hydrolase activity
FGL75_05975	COG3715	PTS system
FGL75_05980	COG3716	PTS system mannose fructose sorbose family IID component
FGL75_05990	COG0588	phosphoglycerate mutase activity
FGL75_06025	COG0126	phosphoglycerate kinase activity
FGL75_06040	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FGL75_06050	COG0517	IMP dehydrogenase activity
FGL75_06050	COG1125	glycine betaine transport
FGL75_06055	COG1174	glycine betaine transport
FGL75_06060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FGL75_06085	COG0328	RNA-DNA hybrid ribonuclease activity
FGL75_06095	COG0564	pseudouridine synthase activity
FGL75_06100	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FGL75_06105	COG0505	Belongs to the CarA family
FGL75_06115	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FGL75_06120	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FGL75_06165	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FGL75_06170	COG2267	carboxylic ester hydrolase activity
FGL75_06180	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FGL75_06185	COG1846	Transcriptional regulator
FGL75_06190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FGL75_06195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGL75_06200	COG2070	2-Nitropropane dioxygenase
FGL75_06210	COG1028	Short-chain dehydrogenase reductase Sdr
FGL75_06215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGL75_06230	COG0439	Biotin carboxylase
FGL75_06235	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FGL75_06250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FGL75_06255	COG1704	LemA family
FGL75_06260	COG0501	Belongs to the peptidase M48B family
FGL75_06265	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGL75_06270	COG1335	isochorismatase
FGL75_06275	COG0673	inositol 2-dehydrogenase activity
FGL75_06280	COG0513	Belongs to the DEAD box helicase family
FGL75_06285	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FGL75_06290	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FGL75_06290	COG1321	iron dependent repressor
FGL75_06315	COG0527	aspartate kinase activity
FGL75_06320	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FGL75_06325	COG0019	diaminopimelate decarboxylase activity
FGL75_06330	COG2171	N-acyltransferase activity
FGL75_06335	COG1473	amidohydrolase
FGL75_06340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGL75_06350	COG0436	Aminotransferase
FGL75_06355	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FGL75_06365	COG0436	Aminotransferase
FGL75_06370	COG4684	Psort location CytoplasmicMembrane, score
FGL75_06385	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FGL75_06390	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FGL75_06395	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FGL75_06400	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FGL75_06405	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FGL75_06410	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FGL75_06415	COG0710	3-dehydroquinate dehydratase activity
FGL75_06430	COG1122	ATPase activity
FGL75_06435	COG4721	ABC-type cobalt transport system, permease component
FGL75_06440	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FGL75_06445	COG0667	Aldo Keto reductase
FGL75_06450	COG4807	Protein conserved in bacteria
FGL75_06460	COG4886	Leucine-rich repeat (LRR) protein
FGL75_06460	COG4932	domain protein
FGL75_06465	COG1914	H( )-stimulated, divalent metal cation uptake system
FGL75_06485	COG2936	dipeptidyl-peptidase activity
FGL75_06490	COG0561	phosphatase activity
FGL75_06495	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FGL75_06500	COG0154	amidase activity
FGL75_06505	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FGL75_06510	COG1597	lipid kinase activity
FGL75_06515	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FGL75_06535	COG0285	dihydrofolate synthase activity
FGL75_06540	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FGL75_06555	COG0018	arginyl-trna synthetase
FGL75_06560	COG1438	arginine binding
FGL75_06565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FGL75_06570	COG3679	Belongs to the UPF0342 family
FGL75_06580	COG4717	serine-type aminopeptidase activity
FGL75_06585	COG3481	metal-dependent phosphohydrolase, HD sub domain
FGL75_06590	COG1070	Carbohydrate kinase
FGL75_06595	COG3402	PFAM membrane-flanked domain
FGL75_06615	COG2610	gluconate transmembrane transporter activity
FGL75_06625	COG0612	Peptidase, M16
FGL75_06630	COG1426	Protein conserved in bacteria
FGL75_06635	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FGL75_06640	COG1546	Belongs to the CinA family
FGL75_06640	COG1058	Belongs to the CinA family
FGL75_06645	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FGL75_06650	COG3973	AAA domain
FGL75_06660	COG0741	lytic transglycosylase activity
FGL75_06665	COG2814	Major facilitator Superfamily
FGL75_06675	COG1278	Cold shock
FGL75_06680	COG0564	pseudouridine synthase activity
FGL75_06690	COG2309	aminopeptidase activity
FGL75_06705	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FGL75_06715	COG0393	Putative heavy-metal-binding
FGL75_06720	COG3475	LICD family
FGL75_06730	COG1388	LysM domain
FGL75_06730	COG1134	teichoic acid transport
FGL75_06735	COG1682	transport, permease protein
FGL75_06750	COG0463	Glycosyl transferase, family 2
FGL75_06750	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FGL75_06755	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FGL75_06775	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FGL75_06780	COG0110	maltose O-acetyltransferase activity
FGL75_06810	COG3711	transcriptional antiterminator
FGL75_06815	COG1263	PTS System
FGL75_06815	COG2190	(PTS) system
FGL75_06815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGL75_06820	COG2723	6-phospho-beta-galactosidase activity
FGL75_06865	COG1501	Belongs to the glycosyl hydrolase 31 family
FGL75_06885	COG0366	Alpha amylase catalytic
FGL75_06885	COG5263	repeat protein
FGL75_06890	COG0024	Methionine aminopeptidase
FGL75_06915	COG0562	UDP-galactopyranose mutase
FGL75_06930	COG0463	Glycosyl transferase, family 2
FGL75_06935	COG1216	Glycosyl transferase, family 2
FGL75_06960	COG1420	regulation of RNA biosynthetic process
FGL75_06970	COG0443	Heat shock 70 kDa protein
FGL75_06975	COG0484	heat shock protein binding
FGL75_06990	COG1234	tRNA 3'-trailer cleavage
FGL75_06995	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FGL75_06995	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FGL75_07000	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FGL75_07020	COG1368	sulfuric ester hydrolase activity
FGL75_07045	COG0110	maltose O-acetyltransferase activity
FGL75_07050	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FGL75_07055	COG4224	UPF0291 protein
FGL75_07060	COG3763	UPF0154 protein
FGL75_07065	COG0204	Acyl-transferase
FGL75_07070	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FGL75_07075	COG2827	Endonuclease containing a URI domain
FGL75_07080	COG0052	Belongs to the universal ribosomal protein uS2 family
FGL75_07085	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FGL75_07105	COG0004	ammonium transporteR
FGL75_07110	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FGL75_07120	COG0617	tRNA 3'-terminal CCA addition
FGL75_07125	COG0488	(ABC) transporter
FGL75_07140	COG0587	DNA-directed DNA polymerase activity
FGL75_07145	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FGL75_07150	COG1490	D-aminoacyl-tRNA deacylase activity
FGL75_07160	COG0475	glutathione-regulated potassium exporter activity
FGL75_07170	COG2996	Protein conserved in bacteria
FGL75_07185	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FGL75_07190	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FGL75_07195	COG1187	pseudouridine synthase activity
FGL75_07200	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FGL75_07210	COG0514	ATP-dependent DNA helicase (RecQ)
FGL75_07220	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FGL75_07225	COG0539	negative regulation of cytoplasmic translation
FGL75_07230	COG1160	GTP binding
FGL75_07235	COG0776	regulation of translation
FGL75_07240	COG0351	phosphomethylpyrimidine kinase
FGL75_07245	COG4720	Psort location CytoplasmicMembrane, score
FGL75_07250	COG2807	transmembrane transport
FGL75_07255	COG0420	3'-5' exonuclease activity
FGL75_07260	COG0419	ATPase involved in DNA repair
FGL75_07275	COG0457	Tetratricopeptide repeat
FGL75_07280	COG2384	SAM-dependent methyltransferase
FGL75_07285	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FGL75_07290	COG2195	Cleaves the N-terminal amino acid of tripeptides
FGL75_07295	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FGL75_07305	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FGL75_07310	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FGL75_07315	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FGL75_07355	COG2169	Transcriptional regulator
FGL75_07360	COG2190	(PTS) system
FGL75_07360	COG2211	Major facilitator Superfamily
FGL75_07370	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FGL75_07380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGL75_07385	COG4708	membrane
FGL75_07390	COG0481	GTPase activity
FGL75_07420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGL75_07425	COG0277	FAD linked oxidase domain protein
FGL75_07465	COG0588	phosphoglycerate mutase activity
FGL75_07470	COG1464	Belongs to the NlpA lipoprotein family
FGL75_07480	COG0071	Belongs to the small heat shock protein (HSP20) family
FGL75_07485	COG0561	phosphatase activity
FGL75_07500	COG3022	response to hydroperoxide
FGL75_07505	COG0406	alpha-ribazole phosphatase activity
FGL75_07520	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FGL75_07530	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FGL75_07540	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FGL75_07550	COG0047	phosphoribosylformylglycinamidine synthase activity
FGL75_07555	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FGL75_07565	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FGL75_07570	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FGL75_07575	COG0138	bifunctional purine biosynthesis protein purh
FGL75_07580	COG0151	Belongs to the GarS family
FGL75_07675	COG2855	membrane
FGL75_07700	COG0640	Transcriptional regulator
FGL75_07740	COG1609	Transcriptional regulator
FGL75_07750	COG0366	Alpha amylase catalytic
FGL75_07760	COG2223	nitrite transmembrane transporter activity
FGL75_07770	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FGL75_07775	COG0351	phosphomethylpyrimidine kinase
FGL75_07790	COG1397	ADP-ribosylglycohydrolase
FGL75_07795	COG1719	4-vinyl reductase, 4VR
FGL75_07800	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FGL75_07810	COG1131	(ABC) transporter
FGL75_07815	COG0537	adenosine 5'-monophosphoramidase activity
FGL75_07825	COG0556	nucleotide-excision repair
FGL75_07840	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FGL75_07850	COG0116	Belongs to the methyltransferase superfamily
FGL75_07860	COG3599	regulation of cell shape
FGL75_07865	COG4474	Belongs to the UPF0398 family
FGL75_07870	COG3331	DNA recombination
FGL75_07880	COG3935	DnaD domain protein
FGL75_07885	COG0017	Asparaginyl-tRNA synthetase
FGL75_07895	COG1199	ATP-dependent helicase activity
FGL75_07895	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FGL75_07900	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FGL75_07915	COG1304	FMN binding
FGL75_07925	COG0706	membrane insertase activity
FGL75_07935	COG5002	protein histidine kinase activity
FGL75_07940	COG0745	RESPONSE REGULATOR receiver
FGL75_07955	COG1484	DNA-dependent DNA replication
FGL75_07965	COG0237	dephospho-CoA kinase activity
FGL75_07970	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FGL75_08020	COG3759	membrane
FGL75_08025	COG0604	alcohol dehydrogenase
FGL75_08085	COG0670	Belongs to the BI1 family
FGL75_08090	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FGL75_08100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGL75_08105	COG1363	Peptidase, m42
FGL75_08110	COG0572	uridine kinase
FGL75_08115	COG5002	protein histidine kinase activity
FGL75_08120	COG0745	RESPONSE REGULATOR receiver
FGL75_08130	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FGL75_08135	COG0358	DNA primase activity
FGL75_08170	COG1002	Type II restriction enzyme, methylase subunits
FGL75_08235	COG1192	Involved in chromosome partitioning
FGL75_08265	COG0542	response to heat
FGL75_08320	COG0446	pyridine nucleotide-disulphide oxidoreductase
FGL75_08330	COG1125	glycine betaine transport
FGL75_08340	COG2217	Heavy metal translocating P-type atpase
FGL75_08455	COG1131	(ABC) transporter
FGL75_08460	COG3655	Transcriptional regulator
FGL75_08495	COG1619	proteins homologs of microcin C7 resistance protein MccF
FGL75_08535	COG1304	FMN binding
FGL75_08540	COG1611	Belongs to the LOG family
FGL75_08555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGL75_08560	COG1554	hydrolase, family 65, central catalytic
FGL75_08565	COG2190	(PTS) system
FGL75_08565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGL75_08565	COG1263	PTS System
FGL75_08575	COG2188	Transcriptional regulator
FGL75_08590	COG2190	(PTS) system
FGL75_08590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGL75_08590	COG1263	PTS System
FGL75_08600	COG0024	Methionine aminopeptidase
FGL75_08610	COG3706	GGDEF domain
FGL75_08635	COG4166	transmembrane transport
FGL75_08650	COG0508	dehydrogenase complex catalyzes the overall conversion of
FGL75_08665	COG0095	Lipoate-protein ligase
FGL75_08670	COG3480	Lon protease (S16) C-terminal proteolytic domain
FGL75_08675	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FGL75_08680	COG0742	ribosomal rna small subunit methyltransferase
FGL75_08685	COG4471	UPF0298 protein
FGL75_08690	COG0772	Belongs to the SEDS family
FGL75_08700	COG0483	inositol monophosphate 1-phosphatase activity
FGL75_08730	COG1597	lipid kinase activity
FGL75_08735	COG1597	lipid kinase activity
FGL75_08745	COG1464	Belongs to the NlpA lipoprotein family
FGL75_08750	COG0446	pyridine nucleotide-disulphide oxidoreductase
FGL75_08765	COG4175	Glycine betaine
FGL75_08765	COG3448	diguanylate cyclase activity
FGL75_08775	COG1227	inorganic diphosphatase activity
FGL75_08785	COG0187	DNA topoisomerase II activity
FGL75_08790	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FGL75_08800	COG4974	Belongs to the 'phage' integrase family
FGL75_08805	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FGL75_08810	COG0758	DNA mediated transformation
FGL75_08815	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FGL75_08835	COG2755	lipolytic protein G-D-S-L family
FGL75_08840	COG1307	EDD domain protein, DegV family
FGL75_08845	COG1307	EDD domain protein, DegV family
FGL75_08855	COG3142	Participates in the control of copper homeostasis
FGL75_08865	COG0196	riboflavin kinase activity
FGL75_08870	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FGL75_08875	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FGL75_08880	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FGL75_08890	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FGL75_08895	COG0195	Participates in both transcription termination and antitermination
FGL75_08900	COG0779	Required for maturation of 30S ribosomal subunits
FGL75_08905	COG2239	Acts as a magnesium transporter
FGL75_08910	COG0564	pseudouridine synthase activity
FGL75_08915	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FGL75_08920	COG2357	RelA SpoT domain protein
FGL75_08935	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FGL75_08945	COG0546	phosphoglycolate phosphatase activity
FGL75_08995	COG3118	belongs to the thioredoxin family
FGL75_09000	COG1193	negative regulation of DNA recombination
FGL75_09005	COG1286	toxin biosynthetic process
FGL75_09015	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FGL75_09020	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FGL75_09025	COG0544	peptidyl-prolyl cis-trans isomerase activity
FGL75_09030	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FGL75_09045	COG0268	Binds directly to 16S ribosomal RNA
FGL75_09050	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FGL75_09055	COG1466	dna polymerase III delta subunit
FGL75_09060	COG0658	competence protein
FGL75_09060	COG2333	competence protein COMEC
FGL75_09065	COG1555	photosystem II stabilization
FGL75_09065	COG1596	polysaccharide export
FGL75_09085	COG4472	Bacterial protein of unknown function (DUF965)
FGL75_09090	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FGL75_09095	COG0513	Belongs to the DEAD box helicase family
FGL75_09100	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FGL75_09105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FGL75_09110	COG1862	Preprotein translocase
FGL75_09150	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FGL75_09155	COG2255	four-way junction helicase activity
FGL75_09160	COG0632	four-way junction helicase activity
FGL75_09175	COG1739	Uncharacterized protein family UPF0029
FGL75_09180	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FGL75_09185	COG0322	excinuclease ABC activity
FGL75_09190	COG1668	transmembrane transport
FGL75_09195	COG4152	abc transporter atp-binding protein
FGL75_09200	COG1674	ftsk spoiiie
FGL75_09210	COG0628	permease
FGL75_09215	COG2706	6-phosphogluconolactonase activity
FGL75_09220	COG0751	glycine-tRNA ligase activity
FGL75_09225	COG0752	glycyl-tRNA synthetase alpha subunit
FGL75_09230	COG1381	Involved in DNA repair and RecF pathway recombination
FGL75_09235	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FGL75_09240	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FGL75_09245	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FGL75_09270	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FGL75_09300	COG0668	transmembrane transport
FGL75_09345	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FGL75_09350	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FGL75_09360	COG4619	ABC transporter
FGL75_09365	COG0390	transport system, permease component
FGL75_09385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGL75_09390	COG0783	Belongs to the Dps family
FGL75_09415	COG0604	alcohol dehydrogenase
FGL75_09430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FGL75_09455	COG1733	regulation of RNA biosynthetic process
FGL75_09460	COG0693	protein deglycase activity
FGL75_09475	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FGL75_09505	COG5039	Polysaccharide pyruvyl transferase
FGL75_09510	COG2814	Major facilitator Superfamily
FGL75_09515	COG2261	transglycosylase associated protein
FGL75_09525	COG2801	Transposase and inactivated derivatives
FGL75_09530	COG1028	Short-chain dehydrogenase reductase Sdr
FGL75_09565	COG3646	Phage regulatory protein
FGL75_09655	COG2801	Transposase and inactivated derivatives
FGL75_09715	COG0640	Transcriptional regulator
FGL75_09725	COG3118	belongs to the thioredoxin family
FGL75_09730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FGL75_09735	COG1794	racemase activity, acting on amino acids and derivatives
FGL75_09740	COG0492	ferredoxin-NADP+ reductase activity
FGL75_09750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGL75_09805	COG0783	Belongs to the Dps family
FGL75_09815	COG1940	carbohydrate kinase activity
FGL75_09830	COG1063	alcohol dehydrogenase